locus-tag	class	description
CBI36_RS00005	COG1671	Belongs to the UPF0178 family
CBI36_RS00015	COG2814	Major facilitator Superfamily
CBI36_RS00025	COG2835	tetraacyldisaccharide 4'-kinase activity
CBI36_RS00030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBI36_RS00040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CBI36_RS00065	COG0778	Nitroreductase
CBI36_RS00075	COG0456	acetyltransferase
CBI36_RS00085	COG1570	exodeoxyribonuclease VII activity
CBI36_RS00100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CBI36_RS00105	COG1012	belongs to the aldehyde dehydrogenase family
CBI36_RS00115	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CBI36_RS00130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CBI36_RS00140	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CBI36_RS00145	COG1053	succinate dehydrogenase
CBI36_RS00150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CBI36_RS00165	COG0126	phosphoglycerate kinase activity
CBI36_RS00175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBI36_RS00185	COG0156	8-amino-7-oxononanoate synthase activity
CBI36_RS00195	COG0405	Gamma-glutamyltransferase
CBI36_RS00215	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CBI36_RS00225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CBI36_RS00250	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CBI36_RS00255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CBI36_RS00265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CBI36_RS00275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CBI36_RS00280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CBI36_RS00285	COG0539	negative regulation of cytoplasmic translation
CBI36_RS00300	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CBI36_RS00305	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CBI36_RS00310	COG1420	regulation of RNA biosynthetic process
CBI36_RS00315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CBI36_RS00350	COG0772	Belongs to the SEDS family
CBI36_RS00355	COG0768	penicillin binding
CBI36_RS00375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBI36_RS00380	COG1612	heme a metabolic process
CBI36_RS00390	COG2814	Major facilitator Superfamily
CBI36_RS00400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBI36_RS00405	COG1289	transmembrane transporter activity
CBI36_RS00415	COG1573	uracil-dna glycosylase
CBI36_RS00435	COG0670	Belongs to the BI1 family
CBI36_RS00460	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CBI36_RS00475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CBI36_RS00490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBI36_RS00510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CBI36_RS00535	COG1028	Short-chain dehydrogenase reductase Sdr
CBI36_RS00540	COG0586	Pfam SNARE associated Golgi protein
CBI36_RS00550	COG0281	malic enzyme
CBI36_RS00580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBI36_RS00585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CBI36_RS00590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CBI36_RS00595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CBI36_RS00600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CBI36_RS00605	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBI36_RS00610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CBI36_RS00615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBI36_RS00630	COG1113	amino acid transport
CBI36_RS00635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBI36_RS00640	COG4208	sulfate ABC transporter
CBI36_RS00660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CBI36_RS00665	COG2207	Transcriptional regulator
CBI36_RS00670	COG4303	Ethanolamine ammonia lyase large subunit
CBI36_RS00675	COG4302	ethanolamine ammonia-lyase activity
CBI36_RS00680	COG1113	amino acid transport
CBI36_RS00690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBI36_RS00705	COG1278	Cold shock
CBI36_RS00745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBI36_RS00755	COG0784	Response regulator, receiver
CBI36_RS00755	COG2205	protein histidine kinase activity
CBI36_RS00780	COG3842	ATPase activity
CBI36_RS00900	COG1475	DNA binding
CBI36_RS00920	COG3177	Filamentation induced by cAMP protein fic
CBI36_RS00965	COG2983	Belongs to the UPF0260 family
CBI36_RS01005	COG1566	PFAM secretion protein HlyD family protein
CBI36_RS01025	COG1657	PFAM Prenyltransferase squalene oxidase
CBI36_RS01030	COG1233	COG1233 Phytoene dehydrogenase and related
CBI36_RS01035	COG1562	ergosterol biosynthetic process
CBI36_RS01040	COG1562	ergosterol biosynthetic process
CBI36_RS01045	COG1215	transferase activity, transferring glycosyl groups
CBI36_RS01050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBI36_RS01060	COG0287	Prephenate dehydrogenase
CBI36_RS01070	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CBI36_RS01080	COG0450	alkyl hydroperoxide reductase
CBI36_RS01085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBI36_RS01095	COG2353	YceI-like domain
CBI36_RS01105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CBI36_RS01115	COG0488	(ABC) transporter
CBI36_RS01135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CBI36_RS01145	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CBI36_RS01150	COG0343	queuine tRNA-ribosyltransferase activity
CBI36_RS01165	COG1881	PFAM PEBP family protein
CBI36_RS01180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CBI36_RS01195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBI36_RS01225	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CBI36_RS01230	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CBI36_RS01245	COG0667	Aldo Keto reductase
CBI36_RS01255	COG0556	nucleotide-excision repair
CBI36_RS01265	COG0612	Peptidase, M16
CBI36_RS01285	COG0463	Glycosyl transferase, family 2
CBI36_RS01300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBI36_RS01310	COG0167	dihydroorotate dehydrogenase activity
CBI36_RS01325	COG1692	metallophosphoesterase
CBI36_RS01330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CBI36_RS01360	COG0352	thiamine-phosphate diphosphorylase activity
CBI36_RS01385	COG1509	lysine 2,3-aminomutase activity
CBI36_RS01395	COG0024	Methionine aminopeptidase
CBI36_RS01400	COG1686	Belongs to the peptidase S11 family
CBI36_RS01405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CBI36_RS01420	COG2326	polyphosphate kinase activity
CBI36_RS01425	COG1678	Uncharacterized ACR, COG1678
CBI36_RS01430	COG1660	Displays ATPase and GTPase activities
CBI36_RS01440	COG2205	protein histidine kinase activity
CBI36_RS01445	COG0745	RESPONSE REGULATOR receiver
CBI36_RS01450	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CBI36_RS01455	COG0443	Heat shock 70 kDa protein
CBI36_RS01460	COG0484	heat shock protein binding
CBI36_RS01465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CBI36_RS01470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CBI36_RS01475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CBI36_RS01480	COG0138	bifunctional purine biosynthesis protein purh
CBI36_RS01495	COG0697	spore germination
CBI36_RS01505	COG0752	glycyl-tRNA synthetase alpha subunit
CBI36_RS01515	COG1396	sequence-specific DNA binding
CBI36_RS01520	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CBI36_RS01540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CBI36_RS01550	COG0598	Magnesium transport protein CorA
CBI36_RS01555	COG0133	tryptophan synthase activity
CBI36_RS01560	COG0159	tryptophan synthase activity
CBI36_RS01565	COG0493	'glutamate synthase
CBI36_RS01575	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CBI36_RS01580	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CBI36_RS01585	COG0745	RESPONSE REGULATOR receiver
CBI36_RS01595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CBI36_RS01625	COG1253	flavin adenine dinucleotide binding
CBI36_RS01630	COG0604	alcohol dehydrogenase
CBI36_RS01640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBI36_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
CBI36_RS01660	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBI36_RS01665	COG3956	TIGRFAM MazG family protein
CBI36_RS01675	COG0326	Molecular chaperone. Has ATPase activity
CBI36_RS01780	COG1396	sequence-specific DNA binding
CBI36_RS01805	COG0629	single-stranded DNA binding
CBI36_RS02100	COG2755	lipolytic protein G-D-S-L family
CBI36_RS02100	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CBI36_RS02125	COG1396	sequence-specific DNA binding
CBI36_RS02125	COG3800	Transcriptional regulator
CBI36_RS02130	COG2079	MmgE PrpD family protein
CBI36_RS02135	COG0372	Belongs to the citrate synthase family
CBI36_RS02140	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CBI36_RS02145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBI36_RS02150	COG2814	Major facilitator Superfamily
CBI36_RS02155	COG2319	Wd-40 repeat
CBI36_RS02165	COG2309	aminopeptidase activity
CBI36_RS02180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CBI36_RS02190	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CBI36_RS02195	COG0193	aminoacyl-tRNA hydrolase activity
CBI36_RS02200	COG0012	GTP binding
CBI36_RS02205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CBI36_RS02210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CBI36_RS02215	COG0799	negative regulation of ribosome biogenesis
CBI36_RS02220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CBI36_RS02255	COG0247	lactate metabolic process
CBI36_RS02260	COG1139	Iron-sulfur cluster binding protein
CBI36_RS02270	COG0697	spore germination
CBI36_RS02275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBI36_RS02280	COG0717	Belongs to the dCTP deaminase family
CBI36_RS02295	COG3394	polysaccharide catabolic process
CBI36_RS02315	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CBI36_RS02330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CBI36_RS02335	COG1253	flavin adenine dinucleotide binding
CBI36_RS02340	COG0741	lytic transglycosylase activity
CBI36_RS02345	COG1573	uracil-dna glycosylase
CBI36_RS02355	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CBI36_RS02365	COG4221	oxidoreductase activity
CBI36_RS02395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CBI36_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
CBI36_RS02445	COG0025	NhaP-type Na H and K H
CBI36_RS02450	COG4771	TonB-dependent receptor
CBI36_RS02460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBI36_RS02465	COG1120	ATPase activity
CBI36_RS02470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CBI36_RS02475	COG2971	BadF BadG BcrA BcrD
CBI36_RS02480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CBI36_RS02500	COG0415	Belongs to the DNA photolyase family
CBI36_RS02505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBI36_RS02535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CBI36_RS02620	COG1012	belongs to the aldehyde dehydrogenase family
CBI36_RS02785	COG4626	Terminase
CBI36_RS02785	COG1802	Transcriptional regulator
CBI36_RS02995	COG4774	siderophore transport
CBI36_RS03110	COG1054	Belongs to the UPF0176 family
CBI36_RS03265	COG1959	2 iron, 2 sulfur cluster binding
CBI36_RS03270	COG4221	oxidoreductase activity
CBI36_RS03275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CBI36_RS03310	COG1607	acyl-coa hydrolase
CBI36_RS03350	COG0306	phosphate transporter
CBI36_RS03360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CBI36_RS03365	COG0022	dehydrogenase e1 component
CBI36_RS03375	COG0071	Belongs to the small heat shock protein (HSP20) family
CBI36_RS03385	COG1252	NADH dehydrogenase
CBI36_RS03395	COG0523	cobalamin synthesis protein
CBI36_RS03405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CBI36_RS03415	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CBI36_RS03420	COG0596	Alpha beta hydrolase
CBI36_RS03435	COG1297	OPT oligopeptide transporter protein
CBI36_RS03470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CBI36_RS03480	COG0469	pyruvate kinase activity
CBI36_RS03500	COG1217	gtp-binding protein TYPA
CBI36_RS03510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBI36_RS03515	COG0492	ferredoxin-NADP+ reductase activity
CBI36_RS03520	COG0538	isocitrate dehydrogenase activity
CBI36_RS03560	COG4993	Dehydrogenase
CBI36_RS03575	COG0481	GTPase activity
CBI36_RS03580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBI36_RS03585	COG2813	Specifically methylates the guanine in position
CBI36_RS03585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBI36_RS03590	COG0513	Belongs to the DEAD box helicase family
CBI36_RS03615	COG1758	RNA polymerase activity
CBI36_RS03620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBI36_RS03625	COG0736	holo-[acyl-carrier-protein] synthase activity
CBI36_RS03630	COG0681	Belongs to the peptidase S26 family
CBI36_RS03635	COG0571	ribonuclease III activity
CBI36_RS03645	COG0528	UMP kinase activity
CBI36_RS03650	COG0233	cytoplasmic translational termination
CBI36_RS03655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CBI36_RS03665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CBI36_RS03670	COG0750	zinc metalloprotease
CBI36_RS03685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBI36_RS03690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CBI36_RS03695	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBI36_RS03700	COG3494	Protein of unknown function (DUF1009)
CBI36_RS03705	COG0346	lactoylglutathione lyase activity
CBI36_RS03715	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CBI36_RS03720	COG0594	ribonuclease P activity
CBI36_RS03725	COG0706	membrane insertase activity
CBI36_RS03730	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CBI36_RS03735	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBI36_RS03740	COG2171	N-acyltransferase activity
CBI36_RS03745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBI36_RS03755	COG0101	tRNA pseudouridine synthase activity
CBI36_RS03760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBI36_RS03765	COG0242	peptide deformylase activity
CBI36_RS03785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CBI36_RS03795	COG0633	Ferredoxin
CBI36_RS03795	COG3217	Mosc domain protein beta barrel domain protein
CBI36_RS03800	COG1137	ATPase activity
CBI36_RS03815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CBI36_RS03815	COG0517	IMP dehydrogenase activity
CBI36_RS03825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBI36_RS03840	COG0194	GDP metabolic process
CBI36_RS03845	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CBI36_RS03845	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CBI36_RS03850	COG2942	2-epimerase
CBI36_RS03855	COG0305	Participates in initiation and elongation during chromosome replication
CBI36_RS03860	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CBI36_RS03860	COG3264	Mechanosensitive ion channel
CBI36_RS03865	COG1127	ABC transporter
CBI36_RS03870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBI36_RS03900	COG1113	amino acid transport
CBI36_RS03910	COG0506	proline dehydrogenase activity
CBI36_RS03910	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBI36_RS03910	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBI36_RS03925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBI36_RS03955	COG2096	Adenosyltransferase
CBI36_RS03970	COG0277	FAD linked oxidase domain protein
CBI36_RS03980	COG0009	L-threonylcarbamoyladenylate synthase
CBI36_RS03990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CBI36_RS04000	COG0656	L-ascorbic acid biosynthetic process
CBI36_RS04010	COG1643	Atp-dependent helicase
CBI36_RS04030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CBI36_RS04035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBI36_RS04055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBI36_RS04060	COG0235	Class ii aldolase
CBI36_RS04065	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CBI36_RS04070	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CBI36_RS04075	COG0196	riboflavin kinase activity
CBI36_RS04080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CBI36_RS04085	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CBI36_RS04095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CBI36_RS04105	COG5006	permease, DMT superfamily
CBI36_RS04110	COG0187	DNA topoisomerase II activity
CBI36_RS04125	COG1959	2 iron, 2 sulfur cluster binding
CBI36_RS04130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CBI36_RS04135	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CBI36_RS04135	COG2885	chlorophyll binding
CBI36_RS04145	COG0793	Belongs to the peptidase S41A family
CBI36_RS04150	COG0557	exoribonuclease II activity
CBI36_RS04155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CBI36_RS04160	COG0758	DNA mediated transformation
CBI36_RS04165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CBI36_RS04170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CBI36_RS04175	COG0540	Belongs to the ATCase OTCase family
CBI36_RS04180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBI36_RS04185	COG0658	competence protein
CBI36_RS04185	COG2333	competence protein COMEC
CBI36_RS04190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBI36_RS04195	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CBI36_RS04205	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBI36_RS04225	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CBI36_RS04240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBI36_RS04275	COG3260	NADH ubiquinone oxidoreductase 20
CBI36_RS04280	COG1183	phosphatidylcholine synthase activity
CBI36_RS04285	COG0688	phosphatidylethanolamine metabolic process
CBI36_RS04290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBI36_RS04300	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CBI36_RS04300	COG2885	chlorophyll binding
CBI36_RS04305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CBI36_RS04315	COG4974	Belongs to the 'phage' integrase family
CBI36_RS04320	COG0825	malonyl-CoA metabolic process
CBI36_RS04325	COG1546	Belongs to the CinA family
CBI36_RS04325	COG1058	Belongs to the CinA family
CBI36_RS04345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CBI36_RS04350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CBI36_RS04355	COG0181	hydroxymethylbilane synthase activity
CBI36_RS04365	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CBI36_RS04370	COG0406	alpha-ribazole phosphatase activity
CBI36_RS04380	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CBI36_RS04400	COG0408	coproporphyrinogen oxidase activity
CBI36_RS04405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CBI36_RS04405	COG2857	Cytochrome c1
CBI36_RS04410	COG2857	Cytochrome c1
CBI36_RS04410	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CBI36_RS04415	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CBI36_RS04435	COG0778	Nitroreductase
CBI36_RS04465	COG3551	Protein conserved in bacteria
CBI36_RS04560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBI36_RS04650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CBI36_RS04655	COG1902	pentaerythritol trinitrate reductase activity
CBI36_RS04660	COG0640	Transcriptional regulator
CBI36_RS04670	COG3591	Belongs to the peptidase S1B family
CBI36_RS04675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBI36_RS04685	COG0019	diaminopimelate decarboxylase activity
CBI36_RS04690	COG0165	Argininosuccinate lyase
CBI36_RS04710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CBI36_RS04715	COG0237	dephospho-CoA kinase activity
CBI36_RS04720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CBI36_RS04740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBI36_RS04750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CBI36_RS04755	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CBI36_RS04765	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CBI36_RS04770	COG0248	Ppx GppA phosphatase
CBI36_RS04785	COG1121	(ABC) transporter
CBI36_RS04810	COG1289	transmembrane transporter activity
CBI36_RS04815	COG1289	transmembrane transporter activity
CBI36_RS04835	COG3088	subunit of a heme lyase
CBI36_RS04840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBI36_RS04845	COG1138	Cytochrome C-type biogenesis protein
CBI36_RS04855	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBI36_RS04890	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CBI36_RS04920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CBI36_RS04930	COG0477	Major facilitator Superfamily
CBI36_RS04935	COG1322	Protein conserved in bacteria
CBI36_RS04965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CBI36_RS04970	COG0081	regulation of translation
CBI36_RS04975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CBI36_RS04980	COG0222	ribosome binding
CBI36_RS04990	COG0085	RNA polymerase activity
CBI36_RS04995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CBI36_RS05000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CBI36_RS05005	COG0049	tRNA binding
CBI36_RS05010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBI36_RS05015	COG0051	transcription antitermination factor activity, RNA binding
CBI36_RS05020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CBI36_RS05025	COG0088	Forms part of the polypeptide exit tunnel
CBI36_RS05030	COG0089	rRNA binding
CBI36_RS05035	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CBI36_RS05040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CBI36_RS05045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CBI36_RS05050	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CBI36_RS05055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CBI36_RS05060	COG0255	Belongs to the universal ribosomal protein uL29 family
CBI36_RS05065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CBI36_RS05070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CBI36_RS05075	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CBI36_RS05080	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CBI36_RS05085	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CBI36_RS05090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CBI36_RS05095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CBI36_RS05100	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CBI36_RS05105	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CBI36_RS05110	COG1841	ribosomal large subunit assembly
CBI36_RS05115	COG0200	Binds to the 23S rRNA
CBI36_RS05125	COG0563	adenylate kinase activity
CBI36_RS05130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CBI36_RS05135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CBI36_RS05140	COG0202	RNA polymerase activity
CBI36_RS05145	COG0203	ribosomal protein L17
CBI36_RS05155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBI36_RS05160	COG1116	anion transmembrane transporter activity
CBI36_RS05170	COG5487	UPF0391 membrane protein
CBI36_RS05190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBI36_RS05200	COG3237	CsbD-like
CBI36_RS05205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CBI36_RS05210	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CBI36_RS05235	COG0714	Associated with various cellular activities
CBI36_RS05245	COG0617	tRNA 3'-terminal CCA addition
CBI36_RS05250	COG1132	(ABC) transporter
CBI36_RS05265	COG1051	belongs to the nudix hydrolase family
CBI36_RS05275	COG0793	Belongs to the peptidase S41A family
CBI36_RS05290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CBI36_RS05295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBI36_RS05300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBI36_RS05305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBI36_RS05310	COG0505	Belongs to the CarA family
CBI36_RS05320	COG0358	DNA primase activity
CBI36_RS05325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CBI36_RS05335	COG0360	Binds together with S18 to 16S ribosomal RNA
CBI36_RS05340	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CBI36_RS05345	COG0359	binds to the 23S rRNA
CBI36_RS05350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBI36_RS05355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CBI36_RS05385	COG1132	(ABC) transporter
CBI36_RS05390	COG1802	Transcriptional regulator
CBI36_RS05395	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CBI36_RS05405	COG0850	regulation of cytokinetic process
CBI36_RS05415	COG2081	HI0933 family
CBI36_RS05420	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CBI36_RS05430	COG0859	PFAM glycosyl transferase family 9
CBI36_RS05430	COG0457	Tetratricopeptide repeat
CBI36_RS05440	COG3781	membrane
CBI36_RS05445	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CBI36_RS05460	COG2884	Cell division ATP-binding protein ftsE
CBI36_RS05485	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CBI36_RS05490	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CBI36_RS05495	COG2166	iron-sulfur cluster assembly
CBI36_RS05510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CBI36_RS05510	COG2010	Cytochrome c
CBI36_RS05515	COG0246	Mannitol dehydrogenase
CBI36_RS05520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CBI36_RS05525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CBI36_RS05530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CBI36_RS05535	COG0072	phenylalanine-tRNA ligase activity
CBI36_RS05535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBI36_RS05540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CBI36_RS05545	COG0747	negative chemotaxis
CBI36_RS05570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CBI36_RS05585	COG0473	3-isopropylmalate dehydrogenase activity
CBI36_RS05590	COG0006	proline dipeptidase activity
CBI36_RS05595	COG2264	protein methyltransferase activity
CBI36_RS05605	COG2003	Belongs to the UPF0758 family
CBI36_RS05610	COG2003	Belongs to the UPF0758 family
CBI36_RS05615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CBI36_RS05640	COG0071	Belongs to the small heat shock protein (HSP20) family
CBI36_RS05645	COG0254	rRNA binding
CBI36_RS05650	COG1970	mechanosensitive ion channel activity
CBI36_RS05660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBI36_RS05665	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBI36_RS05675	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CBI36_RS05675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBI36_RS05680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBI36_RS05690	COG0142	geranyltranstransferase activity
CBI36_RS05695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CBI36_RS05700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CBI36_RS05715	COG2062	phosphohistidine phosphatase, SixA
CBI36_RS05720	COG0287	Prephenate dehydrogenase
CBI36_RS05720	COG1605	Chorismate mutase
CBI36_RS05750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CBI36_RS05760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CBI36_RS05770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBI36_RS05780	COG0729	surface antigen
CBI36_RS05800	COG0322	excinuclease ABC activity
CBI36_RS05815	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CBI36_RS05820	COG0314	molybdopterin synthase activity
CBI36_RS05825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBI36_RS05830	COG0156	8-amino-7-oxononanoate synthase activity
CBI36_RS05840	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CBI36_RS05840	COG4106	trans-aconitate 2-methyltransferase activity
CBI36_RS05845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBI36_RS05850	COG0303	'Molybdopterin
CBI36_RS05855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CBI36_RS05865	COG0148	phosphopyruvate hydratase activity
CBI36_RS05885	COG2022	thiamine diphosphate biosynthetic process
CBI36_RS05900	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CBI36_RS05905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CBI36_RS05920	COG0076	glutamate decarboxylase activity
CBI36_RS05935	COG0484	heat shock protein binding
CBI36_RS05940	COG0271	Belongs to the BolA IbaG family
CBI36_RS05950	COG0321	lipoyl(octanoyl) transferase activity
CBI36_RS05970	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CBI36_RS05975	COG2226	methyltransferase
CBI36_RS06000	COG2706	6-phosphogluconolactonase activity
CBI36_RS06005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CBI36_RS06010	COG0527	aspartate kinase activity
CBI36_RS06015	COG2070	2-Nitropropane dioxygenase
CBI36_RS06025	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CBI36_RS06030	COG0124	histidyl-tRNA synthetase
CBI36_RS06035	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CBI36_RS06045	COG2890	protein-(glutamine-N5) methyltransferase activity
CBI36_RS06070	COG1968	undecaprenyl-diphosphatase activity
CBI36_RS06075	COG0531	amino acid
CBI36_RS06090	COG2951	lytic endotransglycosylase activity
CBI36_RS06095	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CBI36_RS06100	COG1686	Belongs to the peptidase S11 family
CBI36_RS06105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CBI36_RS06120	COG0084	hydrolase, TatD family'
CBI36_RS06135	COG0259	pyridoxamine-phosphate oxidase activity
CBI36_RS06140	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CBI36_RS06145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CBI36_RS06150	COG1764	response to oxidative stress
CBI36_RS06155	COG0579	oxidoreductase
CBI36_RS06165	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CBI36_RS06170	COG0602	queuosine metabolic process
CBI36_RS06175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CBI36_RS06185	COG0175	sulfate reduction
CBI36_RS06190	COG0175	sulfate reduction
CBI36_RS06205	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CBI36_RS06215	COG1519	Transferase
CBI36_RS06220	COG1663	tetraacyldisaccharide 4'-kinase activity
CBI36_RS06240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CBI36_RS06245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CBI36_RS06250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBI36_RS06260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CBI36_RS06295	COG1278	Cold shock
CBI36_RS06300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CBI36_RS06305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBI36_RS06310	COG0077	Prephenate dehydratase
CBI36_RS06310	COG1605	Chorismate mutase
CBI36_RS06315	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CBI36_RS06320	COG3474	cytochrome
CBI36_RS06330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBI36_RS06335	COG0606	chelatase, subunit chli
CBI36_RS06340	COG0626	cystathionine gamma-synthase activity
CBI36_RS06345	COG2897	thiosulfate sulfurtransferase activity
CBI36_RS06350	COG0628	permease
CBI36_RS06360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBI36_RS06365	COG0792	nuclease activity
CBI36_RS06375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CBI36_RS06380	COG0271	Belongs to the BolA IbaG family
CBI36_RS06385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBI36_RS06390	COG0047	phosphoribosylformylglycinamidine synthase activity
CBI36_RS06400	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBI36_RS06405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CBI36_RS06410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CBI36_RS06415	COG0861	Integral membrane protein TerC family
CBI36_RS06430	COG1546	Belongs to the CinA family
CBI36_RS06445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CBI36_RS06450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBI36_RS06455	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBI36_RS06460	COG0022	dehydrogenase e1 component
CBI36_RS06460	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBI36_RS06465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CBI36_RS06470	COG0315	cyclic pyranopterin monophosphate synthase activity
CBI36_RS06475	COG0134	indole-3-glycerol-phosphate synthase activity
CBI36_RS06480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBI36_RS06490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CBI36_RS06500	COG0149	triose-phosphate isomerase activity
CBI36_RS06510	COG0504	CTP synthase activity
CBI36_RS06515	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CBI36_RS06525	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CBI36_RS06535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CBI36_RS06540	COG0268	Binds directly to 16S ribosomal RNA
CBI36_RS06545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CBI36_RS06550	COG2226	methyltransferase
CBI36_RS06555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CBI36_RS06560	COG0756	dUTP diphosphatase activity
CBI36_RS06565	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBI36_RS06570	COG1116	anion transmembrane transporter activity
CBI36_RS06575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBI36_RS06580	COG0525	valine-tRNA ligase activity
CBI36_RS06595	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBI36_RS06620	COG1028	Short-chain dehydrogenase reductase Sdr
CBI36_RS06625	COG0456	acetyltransferase
CBI36_RS06630	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CBI36_RS06635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBI36_RS06640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CBI36_RS06650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CBI36_RS06655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CBI36_RS06665	COG1349	DNA-binding transcription factor activity
CBI36_RS06680	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CBI36_RS06685	COG4988	ABC transporter
CBI36_RS06710	COG0784	Response regulator, receiver
CBI36_RS06715	COG0488	(ABC) transporter
CBI36_RS06730	COG2824	Alkylphosphonate utilization operon protein PhnA
CBI36_RS06735	COG0814	amino acid
CBI36_RS06745	COG0384	phenazine biosynthesis protein PhzF
CBI36_RS06785	COG4206	TonB-dependent receptor
CBI36_RS06795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CBI36_RS06820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CBI36_RS06830	COG2233	PERMEase
CBI36_RS06835	COG2351	hydroxyisourate hydrolase activity
CBI36_RS06850	COG2072	flavoprotein involved in K transport
CBI36_RS06860	COG0402	S-adenosylhomocysteine deaminase activity
CBI36_RS06905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBI36_RS06910	COG0842	Transport permease protein
CBI36_RS06910	COG1129	ABC transporter
CBI36_RS06915	COG0842	Transport permease protein
CBI36_RS06930	COG1657	PFAM Prenyltransferase squalene oxidase
CBI36_RS06950	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CBI36_RS06955	COG0753	catalase activity
CBI36_RS06970	COG3459	Glycosyltransferase 36 associated
CBI36_RS07005	COG4178	(ABC) transporter
CBI36_RS07070	COG0477	Major facilitator Superfamily
CBI36_RS07085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBI36_RS07090	COG1116	anion transmembrane transporter activity
CBI36_RS07095	COG0864	Transcriptional regulator
CBI36_RS07100	COG3665	Urea carboxylase-associated protein
CBI36_RS07105	COG3665	Urea carboxylase-associated protein
CBI36_RS07130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBI36_RS07140	COG1960	acyl-CoA dehydrogenase activity
CBI36_RS07165	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CBI36_RS07170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBI36_RS07175	COG4558	Periplasmic binding protein
CBI36_RS07185	COG1321	iron dependent repressor
CBI36_RS07190	COG1914	H( )-stimulated, divalent metal cation uptake system
CBI36_RS07205	COG0848	biopolymer transport protein
CBI36_RS07225	COG4774	siderophore transport
CBI36_RS07240	COG4774	siderophore transport
CBI36_RS07250	COG1191	sigma factor activity
CBI36_RS07255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBI36_RS07265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBI36_RS07275	COG2175	clavaminate synthase activity
CBI36_RS07345	COG2373	Large extracellular alpha-helical protein
CBI36_RS07350	COG4953	penicillin-binding protein 1C
CBI36_RS07395	COG0583	DNA-binding transcription factor activity
CBI36_RS07405	COG4774	siderophore transport
CBI36_RS07415	COG2814	Major facilitator Superfamily
CBI36_RS07425	COG1028	Short-chain dehydrogenase reductase Sdr
CBI36_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
CBI36_RS07440	COG0667	Aldo Keto reductase
CBI36_RS07445	COG1309	transcriptional regulator
CBI36_RS07450	COG0583	DNA-binding transcription factor activity
CBI36_RS07480	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CBI36_RS07485	COG0523	cobalamin synthesis protein
CBI36_RS07490	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CBI36_RS07495	COG0302	gtp cyclohydrolase
CBI36_RS07505	COG0735	belongs to the Fur family
CBI36_RS07510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CBI36_RS07520	COG0640	Transcriptional regulator
CBI36_RS07555	COG1902	pentaerythritol trinitrate reductase activity
CBI36_RS07560	COG0583	DNA-binding transcription factor activity
CBI36_RS07590	COG0655	NAD(P)H dehydrogenase (quinone) activity
CBI36_RS07610	COG1741	Belongs to the pirin family
CBI36_RS07635	COG2807	transmembrane transport
CBI36_RS07640	COG0640	Transcriptional regulator
CBI36_RS07670	COG1012	belongs to the aldehyde dehydrogenase family
CBI36_RS07675	COG1309	transcriptional regulator
CBI36_RS07680	COG2130	NADP-dependent
CBI36_RS07685	COG1764	response to oxidative stress
CBI36_RS07700	COG1309	transcriptional regulator
CBI36_RS07775	COG0741	lytic transglycosylase activity
CBI36_RS07825	COG5489	Protein of unknown function (DUF736)
CBI36_RS07885	COG4372	Transposase
CBI36_RS07920	COG2746	aminoglycoside 3-N-acetyltransferase activity
CBI36_RS07930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CBI36_RS07940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CBI36_RS07980	COG0625	glutathione transferase activity
CBI36_RS07985	COG0587	DNA-directed DNA polymerase activity
CBI36_RS08010	COG0697	spore germination
CBI36_RS08035	COG3701	Conjugal transfer protein
CBI36_RS08050	COG3451	type IV secretory pathway VirB4
CBI36_RS08060	COG3838	Conjugal transfer protein Trbc
CBI36_RS08065	COG4962	Type ii secretion system protein e
CBI36_RS08140	COG1301	dicarboxylic acid transport
CBI36_RS08145	COG0500	methyltransferase
CBI36_RS08150	COG2999	glutathione oxidoreductase activity
CBI36_RS08155	COG2814	Major facilitator Superfamily
CBI36_RS08160	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CBI36_RS08210	COG0114	fumarate hydratase activity
CBI36_RS08270	COG0628	permease
CBI36_RS08290	COG0167	dihydroorotate dehydrogenase activity
CBI36_RS08295	COG0674	pyruvate-flavodoxin oxidoreductase activity
CBI36_RS08295	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CBI36_RS08295	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CBI36_RS08295	COG1013	pyruvate-flavodoxin oxidoreductase activity
CBI36_RS08300	COG0493	'glutamate synthase
CBI36_RS08310	COG1971	Probably functions as a manganese efflux pump
CBI36_RS08320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CBI36_RS08325	COG0746	molybdenum cofactor guanylyltransferase activity
CBI36_RS08330	COG1763	Mo-molybdopterin cofactor biosynthetic process
CBI36_RS08335	COG0303	'Molybdopterin
CBI36_RS08340	COG3058	Necessary for formate dehydrogenase activity
CBI36_RS08345	COG2864	formate dehydrogenase
CBI36_RS08350	COG0437	4 iron, 4 sulfur cluster binding
CBI36_RS08355	COG0243	molybdopterin cofactor binding
CBI36_RS08355	COG3383	formate dehydrogenase (NAD+) activity
CBI36_RS08365	COG0248	Ppx GppA phosphatase
CBI36_RS08370	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CBI36_RS08375	COG1940	carbohydrate kinase activity
CBI36_RS08380	COG0425	Belongs to the sulfur carrier protein TusA family
CBI36_RS08385	COG1722	exodeoxyribonuclease VII activity
CBI36_RS08390	COG0142	geranyltranstransferase activity
CBI36_RS08395	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CBI36_RS08400	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CBI36_RS08410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBI36_RS08415	COG0137	argininosuccinate synthase activity
CBI36_RS08420	COG0545	Peptidyl-prolyl cis-trans isomerase
CBI36_RS08430	COG0180	Tryptophanyl-tRNA synthetase
CBI36_RS08445	COG0745	RESPONSE REGULATOR receiver
CBI36_RS08460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBI36_RS08460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBI36_RS08470	COG0747	negative chemotaxis
CBI36_RS08485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBI36_RS08500	COG4608	Belongs to the ABC transporter superfamily
CBI36_RS08505	COG2070	2-Nitropropane dioxygenase
CBI36_RS08510	COG0671	phosphoesterase, PA-phosphatase related
CBI36_RS08520	COG3511	phospholipase C
CBI36_RS08540	COG1695	Transcriptional regulator
CBI36_RS08550	COG1032	radical SAM domain protein
CBI36_RS08570	COG0668	transmembrane transport
CBI36_RS08585	COG1294	oxidase, subunit
CBI36_RS08590	COG1271	oxidase subunit
CBI36_RS08595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CBI36_RS08600	COG4988	ABC transporter
CBI36_RS08605	COG3128	pkhd-type hydroxylase
CBI36_RS08610	COG4774	siderophore transport
CBI36_RS08625	COG0252	asparaginase activity
CBI36_RS08635	COG2985	domain, Protein
CBI36_RS08650	COG0488	(ABC) transporter
CBI36_RS08660	COG1064	alcohol dehydrogenase
CBI36_RS08675	COG2814	Major facilitator Superfamily
CBI36_RS08685	COG1902	pentaerythritol trinitrate reductase activity
CBI36_RS08690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CBI36_RS08695	COG1518	maintenance of DNA repeat elements
CBI36_RS08710	COG1857	crispr-associated protein
CBI36_RS08725	COG1203	CRISPR-associated helicase, Cas3
CBI36_RS08755	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CBI36_RS08765	COG0583	DNA-binding transcription factor activity
CBI36_RS08800	COG1028	Short-chain dehydrogenase reductase Sdr
CBI36_RS08805	COG0789	Transcriptional regulator
CBI36_RS08825	COG2315	Protein conserved in bacteria
CBI36_RS08830	COG4221	oxidoreductase activity
CBI36_RS08835	COG2814	Major facilitator Superfamily
CBI36_RS08845	COG0655	NAD(P)H dehydrogenase (quinone) activity
CBI36_RS08850	COG0583	DNA-binding transcription factor activity
CBI36_RS08855	COG0667	Aldo Keto reductase
CBI36_RS08860	COG0667	Aldo Keto reductase
CBI36_RS08915	COG0318	PFAM AMP-dependent synthetase and ligase
CBI36_RS08925	COG0156	8-amino-7-oxononanoate synthase activity
CBI36_RS08940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CBI36_RS08965	COG0546	phosphoglycolate phosphatase activity
CBI36_RS08970	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBI36_RS08975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CBI36_RS08990	COG0386	Belongs to the glutathione peroxidase family
CBI36_RS08995	COG1136	(ABC) transporter
CBI36_RS09005	COG0442	prolyl-tRNA aminoacylation
CBI36_RS09015	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CBI36_RS09025	COG1007	ATP synthesis coupled electron transport
CBI36_RS09035	COG0713	ATP synthesis coupled electron transport
CBI36_RS09045	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBI36_RS09050	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CBI36_RS09055	COG1034	ATP synthesis coupled electron transport
CBI36_RS09065	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CBI36_RS09070	COG0649	NAD binding
CBI36_RS09075	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBI36_RS09080	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBI36_RS09095	COG0776	regulation of translation
CBI36_RS09105	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CBI36_RS09110	COG0740	serine-type endopeptidase activity
CBI36_RS09115	COG0544	peptidyl-prolyl cis-trans isomerase activity
CBI36_RS09125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CBI36_RS09125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CBI36_RS09135	COG0513	Belongs to the DEAD box helicase family
CBI36_RS09145	COG0316	Belongs to the HesB IscA family
CBI36_RS09150	COG2151	metal-sulfur cluster biosynthetic enzyme
CBI36_RS09160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CBI36_RS09165	COG0719	Fe-S assembly protein
CBI36_RS09170	COG0396	ATPase activity
CBI36_RS09175	COG0719	Fe-S assembly protein
CBI36_RS09185	COG2733	membrane
CBI36_RS09190	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CBI36_RS09200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBI36_RS09205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CBI36_RS09215	COG5265	(ABC) transporter
CBI36_RS09225	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CBI36_RS09230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CBI36_RS09255	COG0612	Peptidase, M16
CBI36_RS09260	COG0312	modulator of DNA gyrase
CBI36_RS09275	COG0109	protoheme IX farnesyltransferase activity
CBI36_RS09285	COG2226	methyltransferase
CBI36_RS09305	COG0463	Glycosyl transferase, family 2
CBI36_RS09310	COG1522	sequence-specific DNA binding
CBI36_RS09315	COG0492	ferredoxin-NADP+ reductase activity
CBI36_RS09320	COG0583	DNA-binding transcription factor activity
CBI36_RS09325	COG4957	zinc ion binding
CBI36_RS09330	COG0776	regulation of translation
CBI36_RS09360	COG0776	regulation of translation
CBI36_RS09365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBI36_RS09370	COG0416	fatty acid biosynthetic process
CBI36_RS09375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CBI36_RS09395	COG0745	RESPONSE REGULATOR receiver
CBI36_RS09400	COG1846	Transcriptional regulator
CBI36_RS09410	COG0242	peptide deformylase activity
CBI36_RS09415	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CBI36_RS09420	COG0473	3-isopropylmalate dehydrogenase activity
CBI36_RS09425	COG0066	3-isopropylmalate dehydratase activity
CBI36_RS09430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CBI36_RS09435	COG0335	large ribosomal subunit rRNA binding
CBI36_RS09440	COG0336	Belongs to the RNA methyltransferase TrmD family
CBI36_RS09445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CBI36_RS09450	COG0228	four-way junction DNA binding
CBI36_RS09475	COG0564	pseudouridine synthase activity
CBI36_RS09480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBI36_RS09500	COG3572	ergothioneine biosynthetic process
CBI36_RS09505	COG2814	Major facilitator Superfamily
CBI36_RS09510	COG1160	GTP binding
CBI36_RS09535	COG0438	transferase activity, transferring glycosyl groups
CBI36_RS09540	COG0367	asparagine synthase
CBI36_RS09545	COG0354	folic acid binding
CBI36_RS09550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CBI36_RS09555	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBI36_RS09560	COG0659	secondary active sulfate transmembrane transporter activity
CBI36_RS09585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CBI36_RS09595	COG1051	belongs to the nudix hydrolase family
CBI36_RS09600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CBI36_RS09605	COG1923	regulation of RNA biosynthetic process
CBI36_RS09610	COG2204	response regulator
CBI36_RS09635	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CBI36_RS09635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CBI36_RS09640	COG0463	Glycosyl transferase, family 2
CBI36_RS09680	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CBI36_RS09690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CBI36_RS09705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CBI36_RS09710	COG0347	Belongs to the P(II) protein family
CBI36_RS09720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBI36_RS09725	COG0586	Pfam SNARE associated Golgi protein
CBI36_RS09745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CBI36_RS09750	COG0483	inositol monophosphate 1-phosphatase activity
CBI36_RS09755	COG1199	ATP-dependent helicase activity
CBI36_RS09760	COG1278	Cold shock
CBI36_RS09765	COG0412	Dienelactone hydrolase
CBI36_RS09770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CBI36_RS09775	COG0459	protein refolding
CBI36_RS09810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBI36_RS09825	COG0004	ammonium transporteR
CBI36_RS09845	COG4974	Belongs to the 'phage' integrase family
CBI36_RS09855	COG1862	Preprotein translocase
CBI36_RS09870	COG0494	nUDIX hydrolase
CBI36_RS09890	COG0302	gtp cyclohydrolase
CBI36_RS09900	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBI36_RS09930	COG1566	PFAM secretion protein HlyD family protein
CBI36_RS09960	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CBI36_RS09965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CBI36_RS09965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CBI36_RS09970	COG0307	riboflavin synthase, alpha
CBI36_RS09980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CBI36_RS09980	COG2857	Cytochrome c1
CBI36_RS09985	COG2857	Cytochrome c1
CBI36_RS09985	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CBI36_RS09990	COG0723	plastoquinol--plastocyanin reductase activity
CBI36_RS10010	COG2252	PERMEase
CBI36_RS10065	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CBI36_RS10070	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CBI36_RS10075	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CBI36_RS10080	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CBI36_RS10090	COG3750	Belongs to the UPF0335 family
CBI36_RS10095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CBI36_RS10105	COG0657	acetylesterase activity
CBI36_RS10115	COG2001	Belongs to the MraZ family
CBI36_RS10120	COG0275	rRNA processing
CBI36_RS10135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBI36_RS10145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBI36_RS10150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CBI36_RS10160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBI36_RS10165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBI36_RS10170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CBI36_RS10175	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBI36_RS10180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CBI36_RS10185	COG0849	cell division
CBI36_RS10195	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CBI36_RS10200	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBI36_RS10205	COG0497	DNA recombination
CBI36_RS10210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CBI36_RS10215	COG0574	Belongs to the PEP-utilizing enzyme family
CBI36_RS10215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CBI36_RS10220	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CBI36_RS10240	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CBI36_RS10255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBI36_RS10260	COG1335	isochorismatase
CBI36_RS10270	COG2217	Heavy metal translocating P-type atpase
CBI36_RS10280	COG2132	Multicopper oxidase
CBI36_RS10290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CBI36_RS10300	COG0028	Belongs to the TPP enzyme family
CBI36_RS10305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CBI36_RS10310	COG0560	Phosphoserine phosphatase
CBI36_RS10325	COG0513	Belongs to the DEAD box helicase family
CBI36_RS10345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CBI36_RS10350	COG0531	amino acid
CBI36_RS10355	COG0113	porphobilinogen synthase activity
CBI36_RS10360	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CBI36_RS10365	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CBI36_RS10370	COG1381	Involved in DNA repair and RecF pathway recombination
CBI36_RS10375	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CBI36_RS10380	COG0052	Belongs to the universal ribosomal protein uS2 family
CBI36_RS10415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CBI36_RS10420	COG0251	oxidation-reduction process
CBI36_RS10435	COG0436	Aminotransferase
CBI36_RS10440	COG0436	Aminotransferase
CBI36_RS10445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBI36_RS10465	COG3161	chorismate lyase activity
CBI36_RS10470	COG1032	radical SAM domain protein
CBI36_RS10475	COG0105	UTP biosynthetic process
CBI36_RS10480	COG0488	(ABC) transporter
CBI36_RS10490	COG0745	RESPONSE REGULATOR receiver
CBI36_RS10505	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CBI36_RS10510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CBI36_RS10545	COG0328	RNA-DNA hybrid ribonuclease activity
CBI36_RS10550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CBI36_RS10555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CBI36_RS10605	COG1530	ribonuclease E activity
CBI36_RS10610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CBI36_RS10615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CBI36_RS10620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBI36_RS10625	COG0424	maF-like protein
CBI36_RS10635	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CBI36_RS10725	COG0277	FAD linked oxidase domain protein
CBI36_RS10740	COG2308	Evidence 4 Homologs of previously reported genes of
CBI36_RS10765	COG1309	transcriptional regulator
CBI36_RS10770	COG1252	NADH dehydrogenase
CBI36_RS10775	COG1012	belongs to the aldehyde dehydrogenase family
CBI36_RS10780	COG2814	Major facilitator Superfamily
CBI36_RS10790	COG0431	NADPH-dependent FMN reductase
CBI36_RS10800	COG0583	DNA-binding transcription factor activity
CBI36_RS10870	COG0583	DNA-binding transcription factor activity
CBI36_RS10925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CBI36_RS10930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBI36_RS10935	COG1045	serine acetyltransferase
CBI36_RS11050	COG2197	response regulator
CBI36_RS11075	COG4977	sequence-specific DNA binding
CBI36_RS11125	COG4774	siderophore transport
CBI36_RS11170	COG1562	ergosterol biosynthetic process
CBI36_RS11175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CBI36_RS11175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CBI36_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
CBI36_RS11255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBI36_RS11260	COG2814	Major facilitator Superfamily
CBI36_RS11265	COG0583	DNA-binding transcription factor activity
CBI36_RS11270	COG3328	transposase activity
CBI36_RS11285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CBI36_RS11290	COG1414	Transcriptional regulator
CBI36_RS11305	COG0741	lytic transglycosylase activity
CBI36_RS11370	COG5489	Protein of unknown function (DUF736)
CBI36_RS11445	COG0625	glutathione transferase activity
CBI36_RS11450	COG0587	DNA-directed DNA polymerase activity
CBI36_RS11475	COG0697	spore germination
CBI36_RS11500	COG3701	Conjugal transfer protein
CBI36_RS11505	COG3846	protein secretion by the type IV secretion system
CBI36_RS11515	COG3451	type IV secretory pathway VirB4
CBI36_RS11525	COG3838	Conjugal transfer protein Trbc
CBI36_RS11530	COG4962	Type ii secretion system protein e
CBI36_RS11595	COG1051	belongs to the nudix hydrolase family
CBI36_RS11600	COG0583	DNA-binding transcription factor activity
CBI36_RS11605	COG1289	transmembrane transporter activity
CBI36_RS11630	COG4232	protein-disulfide reductase activity
CBI36_RS11640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CBI36_RS11645	COG0805	protein transport
CBI36_RS11650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBI36_RS11655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CBI36_RS11660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CBI36_RS11670	COG0018	arginyl-trna synthetase
CBI36_RS11675	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CBI36_RS11680	COG0316	Belongs to the HesB IscA family
CBI36_RS11685	COG0708	Exodeoxyribonuclease III
CBI36_RS11710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CBI36_RS11715	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CBI36_RS11725	COG0535	radical SAM domain protein
CBI36_RS11735	COG0740	serine-type endopeptidase activity
CBI36_RS11745	COG0436	Aminotransferase
CBI36_RS11755	COG1494	fructose-1,6-bisphosphatase
CBI36_RS11770	COG0564	pseudouridine synthase activity
CBI36_RS11775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBI36_RS11780	COG1120	ATPase activity
CBI36_RS11785	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CBI36_RS11790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBI36_RS11795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBI36_RS11795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBI36_RS11820	COG0477	Major facilitator Superfamily
CBI36_RS11835	COG1294	oxidase, subunit
CBI36_RS11840	COG1271	oxidase subunit
CBI36_RS11855	COG1113	amino acid transport
CBI36_RS11880	COG0135	phosphoribosylanthranilate isomerase activity
CBI36_RS11885	COG0284	orotidine-5'-phosphate decarboxylase activity
CBI36_RS11895	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CBI36_RS11905	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CBI36_RS11910	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CBI36_RS11920	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CBI36_RS11945	COG3145	DNA-N1-methyladenine dioxygenase activity
CBI36_RS11955	COG3620	sequence-specific DNA binding
CBI36_RS11965	COG2011	ABC-type metal ion transport system permease component
CBI36_RS11970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBI36_RS11980	COG0277	FAD linked oxidase domain protein
CBI36_RS11985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CBI36_RS11985	COG1648	precorrin-2 dehydrogenase activity
CBI36_RS12045	COG0848	biopolymer transport protein
CBI36_RS12065	COG1301	dicarboxylic acid transport
CBI36_RS12100	COG2814	Major facilitator Superfamily
CBI36_RS12110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CBI36_RS12115	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CBI36_RS12130	COG0778	Nitroreductase
CBI36_RS12135	COG1492	cobalamin metabolic process
CBI36_RS12150	COG1797	cobyrinic acid a,c-diamide synthase activity
CBI36_RS12175	COG1289	transmembrane transporter activity
CBI36_RS12180	COG1584	GPR1 FUN34 yaaH family protein
CBI36_RS12185	COG1024	Enoyl-CoA hydratase
CBI36_RS12190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBI36_RS12195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CBI36_RS12210	COG0735	belongs to the Fur family
CBI36_RS12225	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CBI36_RS12255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CBI36_RS12290	COG0582	viral genome integration into host DNA
CBI36_RS12295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBI36_RS12295	COG0519	Catalyzes the synthesis of GMP from XMP
CBI36_RS12310	COG2814	Major facilitator Superfamily
CBI36_RS12315	COG0741	lytic transglycosylase activity
CBI36_RS12315	COG1196	nuclear chromosome segregation
CBI36_RS12315	COG0739	heme binding
CBI36_RS12335	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CBI36_RS12345	COG1496	oxidoreductase activity
CBI36_RS12370	COG1742	UPF0060 membrane protein
CBI36_RS12385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBI36_RS12400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CBI36_RS12405	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CBI36_RS12415	COG0363	glucosamine-6-phosphate deaminase activity
CBI36_RS12420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CBI36_RS12425	COG3265	gluconokinase activity
CBI36_RS12450	COG1063	alcohol dehydrogenase
CBI36_RS12460	COG3158	transport of potassium into the cell
CBI36_RS12465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBI36_RS12625	COG2963	transposase activity
CBI36_RS12635	COG4372	Transposase
CBI36_RS12685	COG0789	Transcriptional regulator
CBI36_RS12725	COG1132	(ABC) transporter
CBI36_RS12730	COG1132	(ABC) transporter
CBI36_RS12730	COG2375	cellular response to nickel ion
CBI36_RS12735	COG1917	Cupin 2, conserved barrel domain protein
CBI36_RS12735	COG2207	Transcriptional regulator
CBI36_RS12755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBI36_RS12765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBI36_RS12785	COG2223	nitrite transmembrane transporter activity
CBI36_RS12795	COG2072	flavoprotein involved in K transport
CBI36_RS12810	COG2144	transferase activity, transferring acyl groups
CBI36_RS12835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBI36_RS12840	COG3328	transposase activity
CBI36_RS12855	COG0583	DNA-binding transcription factor activity
CBI36_RS12865	COG2814	Major facilitator Superfamily
CBI36_RS12885	COG0411	ABC transporter
CBI36_RS12905	COG5002	protein histidine kinase activity
CBI36_RS12905	COG2198	Histidine kinase
CBI36_RS12905	COG0784	Response regulator, receiver
CBI36_RS12910	COG0745	RESPONSE REGULATOR receiver
CBI36_RS12925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CBI36_RS12930	COG0830	nickel cation binding
CBI36_RS12935	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CBI36_RS12940	COG0804	urea catabolic process
CBI36_RS12945	COG0832	Belongs to the urease beta subunit family
CBI36_RS12950	COG0831	urea catabolic process
CBI36_RS12955	COG0829	nickel cation binding
CBI36_RS12960	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CBI36_RS12965	COG3961	Belongs to the TPP enzyme family
CBI36_RS12990	COG1393	Belongs to the ArsC family
CBI36_RS13000	COG2818	Glycosylase
CBI36_RS13010	COG0450	alkyl hydroperoxide reductase
CBI36_RS13065	COG2271	Major facilitator Superfamily
CBI36_RS13070	COG3473	Maleate cis-trans isomerase
CBI36_RS13075	COG0596	Alpha beta hydrolase
CBI36_RS13080	COG1335	isochorismatase
CBI36_RS13085	COG2309	aminopeptidase activity
CBI36_RS13090	COG2010	Cytochrome c
CBI36_RS13090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CBI36_RS13095	COG2080	2 iron, 2 sulfur cluster binding
CBI36_RS13100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBI36_RS13105	COG1846	Transcriptional regulator
CBI36_RS13150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBI36_RS13160	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CBI36_RS13180	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CBI36_RS13180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CBI36_RS13185	COG0509	glycine decarboxylation via glycine cleavage system
CBI36_RS13190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CBI36_RS13195	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CBI36_RS13200	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CBI36_RS13210	COG0583	DNA-binding transcription factor activity
CBI36_RS13325	COG0740	serine-type endopeptidase activity
CBI36_RS13415	COG2176	DNA-directed DNA polymerase activity
CBI36_RS13475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CBI36_RS13480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CBI36_RS13495	COG1185	polyribonucleotide nucleotidyltransferase activity
CBI36_RS13500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CBI36_RS13505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CBI36_RS13510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBI36_RS13515	COG1127	ABC transporter
CBI36_RS13520	COG3008	intermembrane lipid transfer
CBI36_RS13520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CBI36_RS13555	COG2274	protein secretion by the type I secretion system
CBI36_RS13565	COG0646	methionine synthase
CBI36_RS13565	COG1410	methionine synthase
CBI36_RS13580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CBI36_RS13590	COG3008	intermembrane lipid transfer
CBI36_RS13595	COG2995	paraquat-inducible protein a
CBI36_RS13605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CBI36_RS13610	COG0463	Glycosyl transferase, family 2
CBI36_RS13615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CBI36_RS13620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CBI36_RS13625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBI36_RS13630	COG0356	it plays a direct role in the translocation of protons across the membrane
CBI36_RS13640	COG0552	protein localization to endoplasmic reticulum
CBI36_RS13645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBI36_RS13650	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CBI36_RS13665	COG0513	Belongs to the DEAD box helicase family
CBI36_RS13685	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CBI36_RS13700	COG0704	Plays a role in the regulation of phosphate uptake
CBI36_RS13705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBI36_RS13710	COG0581	inorganic phosphate transmembrane transporter activity
CBI36_RS13715	COG0573	inorganic phosphate transmembrane transporter activity
CBI36_RS13720	COG0129	dihydroxy-acid dehydratase activity
CBI36_RS13755	COG0489	protein tyrosine kinase activity
CBI36_RS13770	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CBI36_RS13800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBI36_RS13805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CBI36_RS13810	COG1522	sequence-specific DNA binding
CBI36_RS13815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CBI36_RS13820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CBI36_RS13835	COG0779	Required for maturation of 30S ribosomal subunits
CBI36_RS13845	COG0542	response to heat
CBI36_RS13860	COG0765	amino acid transport
CBI36_RS13865	COG1126	abc transporter atp-binding protein
CBI36_RS13875	COG4133	protoheme IX ABC transporter activity
CBI36_RS13895	COG1295	ribonuclease BN
CBI36_RS13905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBI36_RS13910	COG0511	ligase activity, forming carbon-carbon bonds
CBI36_RS13915	COG0439	Biotin carboxylase
CBI36_RS13920	COG2814	Major facilitator Superfamily
CBI36_RS13925	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CBI36_RS13975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBI36_RS13985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CBI36_RS13990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBI36_RS13995	COG0154	amidase activity
CBI36_RS14000	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBI36_RS14010	COG1132	(ABC) transporter
CBI36_RS14020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CBI36_RS14025	COG1194	a g-specific adenine glycosylase
CBI36_RS14050	COG0495	leucyl-tRNA aminoacylation
CBI36_RS14210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBI36_RS14220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBI36_RS14230	COG0590	tRNA wobble adenosine to inosine editing
CBI36_RS14235	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CBI36_RS14240	COG1187	pseudouridine synthase activity
CBI36_RS14245	COG0742	ribosomal rna small subunit methyltransferase
CBI36_RS14250	COG0629	single-stranded DNA binding
CBI36_RS14280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CBI36_RS14290	COG0406	alpha-ribazole phosphatase activity
CBI36_RS14310	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CBI36_RS14315	COG1091	dTDP-4-dehydrorhamnose reductase activity
CBI36_RS14325	COG1674	ftsk spoiiie
CBI36_RS14330	COG0564	pseudouridine synthase activity
CBI36_RS14345	COG0482	sulfurtransferase activity
CBI36_RS14355	COG1104	cysteine desulfurase activity
CBI36_RS14360	COG1104	cysteine desulfurase activity
CBI36_RS14365	COG2945	thiolester hydrolase activity
CBI36_RS14375	COG0215	cysteine-tRNA ligase activity
CBI36_RS14385	COG0285	dihydrofolate synthase activity
CBI36_RS14390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CBI36_RS14405	COG2887	Belongs to the helicase family. UvrD subfamily
CBI36_RS14410	COG0802	atpase or kinase
CBI36_RS14415	COG0745	RESPONSE REGULATOR receiver
CBI36_RS14420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBI36_RS14430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBI36_RS14435	COG0037	tRNA processing
CBI36_RS14445	COG2885	chlorophyll binding
CBI36_RS14450	COG0823	Involved in the tonB-independent uptake of proteins
CBI36_RS14460	COG0848	biopolymer transport protein
CBI36_RS14470	COG0824	Thioesterase
CBI36_RS14475	COG2255	four-way junction helicase activity
CBI36_RS14480	COG0632	four-way junction helicase activity
CBI36_RS14485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CBI36_RS14490	COG0217	transcriptional regulatory protein
CBI36_RS14495	COG0653	protein targeting
CBI36_RS14500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBI36_RS14505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CBI36_RS14530	COG0484	heat shock protein binding
CBI36_RS14565	COG0776	regulation of translation
CBI36_RS14585	COG1216	Glycosyl transferase, family 2
CBI36_RS14600	COG0131	Imidazoleglycerol-phosphate dehydratase
CBI36_RS14605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CBI36_RS14610	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CBI36_RS14615	COG0107	imidazoleglycerol-phosphate synthase activity
CBI36_RS14620	COG0140	phosphoribosyl-ATP diphosphatase activity
CBI36_RS14630	COG0778	Nitroreductase
CBI36_RS14670	COG0357	Ribosomal RNA small subunit methyltransferase G
CBI36_RS14675	COG0445	tRNA wobble uridine modification
CBI36_RS14680	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBI36_RS14685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CBI36_RS14700	COG0582	viral genome integration into host DNA
CBI36_RS14820	COG1802	Transcriptional regulator
CBI36_RS14820	COG4626	Terminase
CBI36_RS14935	COG1611	Belongs to the LOG family
CBI36_RS14950	COG1981	membrane
CBI36_RS14955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBI36_RS14960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CBI36_RS14965	COG0424	maF-like protein