locus-tag	class	description
DB34_RS00010	COG0004	ammonium transporteR
DB34_RS00030	COG4974	Belongs to the 'phage' integrase family
DB34_RS00040	COG1862	Preprotein translocase
DB34_RS00055	COG0494	nUDIX hydrolase
DB34_RS00075	COG2967	ApaG domain
DB34_RS00080	COG0302	gtp cyclohydrolase
DB34_RS00090	COG0521	Mo-molybdopterin cofactor biosynthetic process
DB34_RS00120	COG1566	PFAM secretion protein HlyD family protein
DB34_RS00155	COG3293	Transposase
DB34_RS00160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DB34_RS00165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DB34_RS00165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DB34_RS00170	COG0307	riboflavin synthase, alpha
DB34_RS00180	COG2857	Cytochrome c1
DB34_RS00180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DB34_RS00185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DB34_RS00185	COG2857	Cytochrome c1
DB34_RS00190	COG0723	plastoquinol--plastocyanin reductase activity
DB34_RS00210	COG2252	PERMEase
DB34_RS00285	COG2963	transposase activity
DB34_RS00310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DB34_RS00315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DB34_RS00320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DB34_RS00325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DB34_RS00335	COG3750	Belongs to the UPF0335 family
DB34_RS00340	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DB34_RS00355	COG2001	Belongs to the MraZ family
DB34_RS00360	COG0275	rRNA processing
DB34_RS00375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DB34_RS00385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DB34_RS00390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DB34_RS00400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DB34_RS00405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DB34_RS00410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DB34_RS00415	COG1181	Belongs to the D-alanine--D-alanine ligase family
DB34_RS00420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DB34_RS00425	COG0849	cell division
DB34_RS00440	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DB34_RS00445	COG0497	DNA recombination
DB34_RS00450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DB34_RS00455	COG0574	Belongs to the PEP-utilizing enzyme family
DB34_RS00455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DB34_RS00460	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DB34_RS00480	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DB34_RS00495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DB34_RS00500	COG1335	isochorismatase
DB34_RS00520	COG2132	Multicopper oxidase
DB34_RS00530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DB34_RS00540	COG0028	Belongs to the TPP enzyme family
DB34_RS00545	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DB34_RS00550	COG0560	Phosphoserine phosphatase
DB34_RS00565	COG0513	Belongs to the DEAD box helicase family
DB34_RS00580	COG2988	succinylglutamate desuccinylase activity
DB34_RS00585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DB34_RS00590	COG0531	amino acid
DB34_RS00595	COG0113	porphobilinogen synthase activity
DB34_RS00600	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DB34_RS00605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DB34_RS00610	COG1381	Involved in DNA repair and RecF pathway recombination
DB34_RS00615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DB34_RS00620	COG0052	Belongs to the universal ribosomal protein uS2 family
DB34_RS00660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DB34_RS00665	COG0251	oxidation-reduction process
DB34_RS00680	COG0436	Aminotransferase
DB34_RS00685	COG0436	Aminotransferase
DB34_RS00690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DB34_RS00710	COG3161	chorismate lyase activity
DB34_RS00715	COG1032	radical SAM domain protein
DB34_RS00720	COG0105	UTP biosynthetic process
DB34_RS00725	COG0488	(ABC) transporter
DB34_RS00735	COG0745	RESPONSE REGULATOR receiver
DB34_RS00750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DB34_RS00755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DB34_RS00775	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DB34_RS00790	COG0328	RNA-DNA hybrid ribonuclease activity
DB34_RS00795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DB34_RS00800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DB34_RS00850	COG1530	ribonuclease E activity
DB34_RS00855	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DB34_RS00860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DB34_RS00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DB34_RS00870	COG0424	maF-like protein
DB34_RS00880	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DB34_RS00965	COG0277	FAD linked oxidase domain protein
DB34_RS00980	COG2308	Evidence 4 Homologs of previously reported genes of
DB34_RS01010	COG1309	transcriptional regulator
DB34_RS01015	COG1252	NADH dehydrogenase
DB34_RS01020	COG1012	belongs to the aldehyde dehydrogenase family
DB34_RS01035	COG2814	Major facilitator Superfamily
DB34_RS01045	COG0431	NADPH-dependent FMN reductase
DB34_RS01055	COG0583	DNA-binding transcription factor activity
DB34_RS01090	COG0697	spore germination
DB34_RS01095	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DB34_RS01100	COG1984	allophanate hydrolase subunit 2
DB34_RS01110	COG4221	oxidoreductase activity
DB34_RS01120	COG0439	Biotin carboxylase
DB34_RS01130	COG0436	Aminotransferase
DB34_RS01145	COG0300	oxidoreductase activity
DB34_RS01155	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DB34_RS01160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DB34_RS01165	COG0297	glycogen (starch) synthase activity
DB34_RS01180	COG1028	Short-chain dehydrogenase reductase Sdr
DB34_RS01185	COG0028	Belongs to the TPP enzyme family
DB34_RS01195	COG1999	signal sequence binding
DB34_RS01250	COG0583	DNA-binding transcription factor activity
DB34_RS01280	COG4232	protein-disulfide reductase activity
DB34_RS01290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DB34_RS01295	COG0805	protein transport
DB34_RS01300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DB34_RS01305	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DB34_RS01310	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DB34_RS01320	COG0018	arginyl-trna synthetase
DB34_RS01325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DB34_RS01330	COG0316	Belongs to the HesB IscA family
DB34_RS01335	COG0708	Exodeoxyribonuclease III
DB34_RS01340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DB34_RS01360	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DB34_RS01365	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
DB34_RS01375	COG0535	radical SAM domain protein
DB34_RS01385	COG0740	serine-type endopeptidase activity
DB34_RS01395	COG0436	Aminotransferase
DB34_RS01405	COG1494	fructose-1,6-bisphosphatase
DB34_RS01420	COG0564	pseudouridine synthase activity
DB34_RS01425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB34_RS01430	COG1120	ATPase activity
DB34_RS01435	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DB34_RS01445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DB34_RS01450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DB34_RS01450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DB34_RS01470	COG1294	oxidase, subunit
DB34_RS01475	COG1271	oxidase subunit
DB34_RS01490	COG1113	amino acid transport
DB34_RS01500	COG4993	Dehydrogenase
DB34_RS01510	COG3293	Transposase
DB34_RS01515	COG1942	4-Oxalocrotonate Tautomerase
DB34_RS01520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DB34_RS01525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DB34_RS01540	COG0493	'glutamate synthase
DB34_RS01560	COG1953	Uracil, thiamine, allantoin
DB34_RS01580	COG0284	orotidine-5'-phosphate decarboxylase activity
DB34_RS01590	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DB34_RS01600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DB34_RS01605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DB34_RS01615	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DB34_RS01635	COG3145	DNA-N1-methyladenine dioxygenase activity
DB34_RS01645	COG3620	sequence-specific DNA binding
DB34_RS01655	COG2011	ABC-type metal ion transport system permease component
DB34_RS01660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DB34_RS01670	COG0277	FAD linked oxidase domain protein
DB34_RS01675	COG1648	precorrin-2 dehydrogenase activity
DB34_RS01675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DB34_RS01685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DB34_RS01720	COG2814	Major facilitator Superfamily
DB34_RS01730	COG3128	pkhd-type hydroxylase
DB34_RS01745	COG4774	siderophore transport
DB34_RS01755	COG3293	Transposase
DB34_RS01765	COG0848	biopolymer transport protein
DB34_RS01785	COG1301	dicarboxylic acid transport
DB34_RS01820	COG2814	Major facilitator Superfamily
DB34_RS01830	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DB34_RS01835	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DB34_RS01850	COG0778	Nitroreductase
DB34_RS01855	COG1492	cobalamin metabolic process
DB34_RS01870	COG1797	cobyrinic acid a,c-diamide synthase activity
DB34_RS01895	COG1289	transmembrane transporter activity
DB34_RS01900	COG1584	GPR1 FUN34 yaaH family protein
DB34_RS01905	COG1024	Enoyl-CoA hydratase
DB34_RS01910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DB34_RS01915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DB34_RS01920	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DB34_RS01930	COG0735	belongs to the Fur family
DB34_RS01945	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DB34_RS01965	COG0519	Catalyzes the synthesis of GMP from XMP
DB34_RS01965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DB34_RS01980	COG2814	Major facilitator Superfamily
DB34_RS01985	COG0739	heme binding
DB34_RS01985	COG0741	lytic transglycosylase activity
DB34_RS01985	COG1196	nuclear chromosome segregation
DB34_RS02005	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DB34_RS02015	COG1496	oxidoreductase activity
DB34_RS02045	COG1742	UPF0060 membrane protein
DB34_RS02060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DB34_RS02075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DB34_RS02080	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DB34_RS02090	COG0363	glucosamine-6-phosphate deaminase activity
DB34_RS02095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DB34_RS02100	COG3265	gluconokinase activity
DB34_RS02125	COG0604	alcohol dehydrogenase
DB34_RS02135	COG3158	transport of potassium into the cell
DB34_RS02140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DB34_RS02165	COG0411	ABC transporter
DB34_RS02185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DB34_RS02185	COG2198	Histidine kinase
DB34_RS02185	COG2205	protein histidine kinase activity
DB34_RS02185	COG0784	Response regulator, receiver
DB34_RS02190	COG0745	RESPONSE REGULATOR receiver
DB34_RS02230	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DB34_RS02235	COG0830	nickel cation binding
DB34_RS02240	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DB34_RS02245	COG0804	urea catabolic process
DB34_RS02250	COG0832	Belongs to the urease beta subunit family
DB34_RS02255	COG0831	urea catabolic process
DB34_RS02260	COG0829	nickel cation binding
DB34_RS02265	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DB34_RS02270	COG3961	Belongs to the TPP enzyme family
DB34_RS02295	COG1393	Belongs to the ArsC family
DB34_RS02305	COG2818	Glycosylase
DB34_RS02315	COG0450	alkyl hydroperoxide reductase
DB34_RS02365	COG0583	DNA-binding transcription factor activity
DB34_RS02375	COG2271	Major facilitator Superfamily
DB34_RS02380	COG3473	Maleate cis-trans isomerase
DB34_RS02385	COG0596	Alpha beta hydrolase
DB34_RS02390	COG1335	isochorismatase
DB34_RS02395	COG2309	aminopeptidase activity
DB34_RS02400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DB34_RS02400	COG2010	Cytochrome c
DB34_RS02405	COG2080	2 iron, 2 sulfur cluster binding
DB34_RS02410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DB34_RS02415	COG1846	Transcriptional regulator
DB34_RS02460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DB34_RS02470	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DB34_RS02490	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DB34_RS02490	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DB34_RS02495	COG0509	glycine decarboxylation via glycine cleavage system
DB34_RS02500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DB34_RS02505	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DB34_RS02510	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DB34_RS02520	COG0583	DNA-binding transcription factor activity
DB34_RS02535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DB34_RS02540	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DB34_RS02555	COG1185	polyribonucleotide nucleotidyltransferase activity
DB34_RS02560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DB34_RS02565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DB34_RS02570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DB34_RS02575	COG1127	ABC transporter
DB34_RS02580	COG3008	intermembrane lipid transfer
DB34_RS02580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DB34_RS02625	COG0646	methionine synthase
DB34_RS02625	COG1410	methionine synthase
DB34_RS02640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DB34_RS02650	COG3008	intermembrane lipid transfer
DB34_RS02655	COG2995	paraquat-inducible protein a
DB34_RS02665	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DB34_RS02670	COG0463	Glycosyl transferase, family 2
DB34_RS02675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DB34_RS02680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DB34_RS02685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DB34_RS02690	COG0356	it plays a direct role in the translocation of protons across the membrane
DB34_RS02700	COG0552	protein localization to endoplasmic reticulum
DB34_RS02705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DB34_RS02710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DB34_RS02715	COG0346	lactoylglutathione lyase activity
DB34_RS02725	COG0513	Belongs to the DEAD box helicase family
DB34_RS02745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DB34_RS02760	COG0704	Plays a role in the regulation of phosphate uptake
DB34_RS02765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DB34_RS02775	COG0573	inorganic phosphate transmembrane transporter activity
DB34_RS02780	COG0129	dihydroxy-acid dehydratase activity
DB34_RS02815	COG0489	protein tyrosine kinase activity
DB34_RS02830	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DB34_RS02840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DB34_RS02840	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DB34_RS02855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DB34_RS02860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DB34_RS02865	COG1522	sequence-specific DNA binding
DB34_RS02870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DB34_RS02875	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DB34_RS02890	COG0779	Required for maturation of 30S ribosomal subunits
DB34_RS02900	COG0542	response to heat
DB34_RS02915	COG0765	amino acid transport
DB34_RS02920	COG1126	abc transporter atp-binding protein
DB34_RS02935	COG4133	protoheme IX ABC transporter activity
DB34_RS02955	COG1295	ribonuclease BN
DB34_RS02965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DB34_RS02970	COG0511	ligase activity, forming carbon-carbon bonds
DB34_RS02975	COG0439	Biotin carboxylase
DB34_RS02980	COG2814	Major facilitator Superfamily
DB34_RS02985	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DB34_RS03030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DB34_RS03040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DB34_RS03045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DB34_RS03050	COG0154	amidase activity
DB34_RS03055	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DB34_RS03155	COG2856	Zn peptidase
DB34_RS03210	COG5265	(ABC) transporter
DB34_RS03215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DB34_RS03220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DB34_RS03250	COG0495	leucyl-tRNA aminoacylation
DB34_RS03325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DB34_RS03335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DB34_RS03340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DB34_RS03345	COG0590	tRNA wobble adenosine to inosine editing
DB34_RS03350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DB34_RS03355	COG1187	pseudouridine synthase activity
DB34_RS03360	COG0742	ribosomal rna small subunit methyltransferase
DB34_RS03405	COG0438	transferase activity, transferring glycosyl groups
DB34_RS03415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DB34_RS03420	COG0312	modulator of DNA gyrase
DB34_RS03425	COG0406	alpha-ribazole phosphatase activity
DB34_RS03445	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DB34_RS03450	COG1091	dTDP-4-dehydrorhamnose reductase activity
DB34_RS03460	COG1674	ftsk spoiiie
DB34_RS03465	COG0564	pseudouridine synthase activity
DB34_RS03470	COG3293	Transposase
DB34_RS03490	COG0482	sulfurtransferase activity
DB34_RS03500	COG1104	cysteine desulfurase activity
DB34_RS03505	COG1104	cysteine desulfurase activity
DB34_RS03510	COG2945	thiolester hydrolase activity
DB34_RS03520	COG0215	cysteine-tRNA ligase activity
DB34_RS03530	COG0285	dihydrofolate synthase activity
DB34_RS03535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DB34_RS03550	COG2887	Belongs to the helicase family. UvrD subfamily
DB34_RS03555	COG0802	atpase or kinase
DB34_RS03565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DB34_RS03575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DB34_RS03580	COG0037	tRNA processing
DB34_RS03590	COG2885	chlorophyll binding
DB34_RS03595	COG0823	Involved in the tonB-independent uptake of proteins
DB34_RS03605	COG0848	biopolymer transport protein
DB34_RS03615	COG0824	Thioesterase
DB34_RS03620	COG2255	four-way junction helicase activity
DB34_RS03625	COG0632	four-way junction helicase activity
DB34_RS03630	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DB34_RS03635	COG0217	transcriptional regulatory protein
DB34_RS03640	COG0653	protein targeting
DB34_RS03645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DB34_RS03650	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DB34_RS03660	COG0668	transmembrane transport
DB34_RS03675	COG0484	heat shock protein binding
DB34_RS03715	COG3293	Transposase
DB34_RS03725	COG0776	regulation of translation
DB34_RS03745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DB34_RS03745	COG0463	Glycosyl transferase, family 2
DB34_RS03760	COG0131	Imidazoleglycerol-phosphate dehydratase
DB34_RS03765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DB34_RS03770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DB34_RS03775	COG0107	imidazoleglycerol-phosphate synthase activity
DB34_RS03780	COG0140	phosphoribosyl-ATP diphosphatase activity
DB34_RS03790	COG0778	Nitroreductase
DB34_RS03830	COG0357	Ribosomal RNA small subunit methyltransferase G
DB34_RS03835	COG0445	tRNA wobble uridine modification
DB34_RS03840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DB34_RS03845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DB34_RS03865	COG1611	Belongs to the LOG family
DB34_RS03880	COG1981	membrane
DB34_RS03885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DB34_RS03890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DB34_RS03980	COG0582	viral genome integration into host DNA
DB34_RS03985	COG1671	Belongs to the UPF0178 family
DB34_RS03995	COG2814	Major facilitator Superfamily
DB34_RS04005	COG2835	tetraacyldisaccharide 4'-kinase activity
DB34_RS04010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DB34_RS04045	COG0778	Nitroreductase
DB34_RS04055	COG0456	acetyltransferase
DB34_RS04065	COG1570	exodeoxyribonuclease VII activity
DB34_RS04110	COG1012	belongs to the aldehyde dehydrogenase family
DB34_RS04120	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DB34_RS04135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DB34_RS04145	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DB34_RS04155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DB34_RS04170	COG0126	phosphoglycerate kinase activity
DB34_RS04180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DB34_RS04190	COG0156	8-amino-7-oxononanoate synthase activity
DB34_RS04195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DB34_RS04200	COG0405	Gamma-glutamyltransferase
DB34_RS04220	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DB34_RS04230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DB34_RS04250	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DB34_RS04255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DB34_RS04265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DB34_RS04275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DB34_RS04280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DB34_RS04290	COG0539	negative regulation of cytoplasmic translation
DB34_RS04305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DB34_RS04310	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DB34_RS04315	COG1420	regulation of RNA biosynthetic process
DB34_RS04320	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DB34_RS04355	COG0772	Belongs to the SEDS family
DB34_RS04360	COG0768	penicillin binding
DB34_RS04380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DB34_RS04385	COG1612	heme a metabolic process
DB34_RS04395	COG2814	Major facilitator Superfamily
DB34_RS04405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DB34_RS04410	COG1289	transmembrane transporter activity
DB34_RS04420	COG1573	uracil-dna glycosylase
DB34_RS04440	COG0670	Belongs to the BI1 family
DB34_RS04465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DB34_RS04480	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DB34_RS04495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DB34_RS04515	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DB34_RS04535	COG1028	Short-chain dehydrogenase reductase Sdr
DB34_RS04540	COG0586	Pfam SNARE associated Golgi protein
DB34_RS04555	COG0281	malic enzyme
DB34_RS04585	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DB34_RS04590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DB34_RS04595	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DB34_RS04600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DB34_RS04605	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DB34_RS04610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DB34_RS04615	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DB34_RS04620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DB34_RS04635	COG1113	amino acid transport
DB34_RS04640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DB34_RS04645	COG4208	sulfate ABC transporter
DB34_RS04665	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DB34_RS04670	COG2207	Transcriptional regulator
DB34_RS04675	COG4303	Ethanolamine ammonia lyase large subunit
DB34_RS04680	COG4302	ethanolamine ammonia-lyase activity
DB34_RS04690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DB34_RS04705	COG1278	Cold shock
DB34_RS04735	COG3293	Transposase
DB34_RS04775	COG2983	Belongs to the UPF0260 family
DB34_RS04790	COG3842	ATPase activity
DB34_RS04815	COG1566	PFAM secretion protein HlyD family protein
DB34_RS04835	COG1657	PFAM Prenyltransferase squalene oxidase
DB34_RS04840	COG1233	COG1233 Phytoene dehydrogenase and related
DB34_RS04845	COG1562	ergosterol biosynthetic process
DB34_RS04850	COG1562	ergosterol biosynthetic process
DB34_RS04860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DB34_RS04870	COG0287	Prephenate dehydrogenase
DB34_RS04885	COG0450	alkyl hydroperoxide reductase
DB34_RS04890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DB34_RS04910	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DB34_RS04920	COG0488	(ABC) transporter
DB34_RS04940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DB34_RS04950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DB34_RS04955	COG0343	queuine tRNA-ribosyltransferase activity
DB34_RS04960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DB34_RS04970	COG1881	PFAM PEBP family protein
DB34_RS04995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DB34_RS05010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DB34_RS05040	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DB34_RS05045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DB34_RS05060	COG0667	Aldo Keto reductase
DB34_RS05070	COG0556	nucleotide-excision repair
DB34_RS05080	COG0612	Peptidase, M16
DB34_RS05125	COG3547	Transposase (IS116 IS110 IS902 family)
DB34_RS05145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DB34_RS05160	COG0167	dihydroorotate dehydrogenase activity
DB34_RS05170	COG1051	belongs to the nudix hydrolase family
DB34_RS05175	COG1692	metallophosphoesterase
DB34_RS05180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DB34_RS05205	COG0352	thiamine-phosphate diphosphorylase activity
DB34_RS05230	COG1509	lysine 2,3-aminomutase activity
DB34_RS05240	COG0024	Methionine aminopeptidase
DB34_RS05245	COG1686	Belongs to the peptidase S11 family
DB34_RS05250	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DB34_RS05265	COG2326	polyphosphate kinase activity
DB34_RS05270	COG1678	Uncharacterized ACR, COG1678
DB34_RS05275	COG1660	Displays ATPase and GTPase activities
DB34_RS05285	COG2205	protein histidine kinase activity
DB34_RS05290	COG0745	RESPONSE REGULATOR receiver
DB34_RS05295	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DB34_RS05300	COG0443	Heat shock 70 kDa protein
DB34_RS05305	COG0484	heat shock protein binding
DB34_RS05310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DB34_RS05315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DB34_RS05320	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DB34_RS05325	COG0138	bifunctional purine biosynthesis protein purh
DB34_RS05335	COG0697	spore germination
DB34_RS05345	COG0752	glycyl-tRNA synthetase alpha subunit
DB34_RS05355	COG1396	sequence-specific DNA binding
DB34_RS05365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DB34_RS05385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DB34_RS05395	COG0598	Magnesium transport protein CorA
DB34_RS05400	COG0133	tryptophan synthase activity
DB34_RS05405	COG0159	tryptophan synthase activity
DB34_RS05410	COG0431	NADPH-dependent FMN reductase
DB34_RS05410	COG3976	FMN-binding domain protein
DB34_RS05410	COG1053	succinate dehydrogenase
DB34_RS05420	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DB34_RS05425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DB34_RS05430	COG0745	RESPONSE REGULATOR receiver
DB34_RS05440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DB34_RS05465	COG1253	flavin adenine dinucleotide binding
DB34_RS05470	COG0604	alcohol dehydrogenase
DB34_RS05480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DB34_RS05495	COG1028	Short-chain dehydrogenase reductase Sdr
DB34_RS05500	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DB34_RS05505	COG3956	TIGRFAM MazG family protein
DB34_RS05515	COG0326	Molecular chaperone. Has ATPase activity
DB34_RS05700	COG2079	MmgE PrpD family protein
DB34_RS05705	COG0372	Belongs to the citrate synthase family
DB34_RS05710	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DB34_RS05715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DB34_RS05720	COG2814	Major facilitator Superfamily
DB34_RS05725	COG2319	Wd-40 repeat
DB34_RS05735	COG2309	aminopeptidase activity
DB34_RS05750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DB34_RS05760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DB34_RS05765	COG0193	aminoacyl-tRNA hydrolase activity
DB34_RS05770	COG0012	GTP binding
DB34_RS05775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DB34_RS05780	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DB34_RS05785	COG0799	negative regulation of ribosome biogenesis
DB34_RS05790	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DB34_RS05825	COG0247	lactate metabolic process
DB34_RS05830	COG1139	Iron-sulfur cluster binding protein
DB34_RS05840	COG0697	spore germination
DB34_RS05845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DB34_RS05850	COG0717	Belongs to the dCTP deaminase family
DB34_RS05865	COG3394	polysaccharide catabolic process
DB34_RS05895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DB34_RS05900	COG1253	flavin adenine dinucleotide binding
DB34_RS05905	COG0741	lytic transglycosylase activity
DB34_RS05910	COG1573	uracil-dna glycosylase
DB34_RS05920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DB34_RS05960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DB34_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
DB34_RS06010	COG0025	NhaP-type Na H and K H
DB34_RS06020	COG4771	TonB-dependent receptor
DB34_RS06030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB34_RS06035	COG1120	ATPase activity
DB34_RS06040	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DB34_RS06045	COG2971	BadF BadG BcrA BcrD
DB34_RS06050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DB34_RS06065	COG0415	Belongs to the DNA photolyase family
DB34_RS06070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DB34_RS06095	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DB34_RS06170	COG1012	belongs to the aldehyde dehydrogenase family
DB34_RS06245	COG3293	Transposase
DB34_RS06475	COG2963	transposase activity
DB34_RS06485	COG4372	Transposase
DB34_RS06495	COG2963	transposase activity
DB34_RS06505	COG4372	Transposase
DB34_RS06615	COG4774	siderophore transport
DB34_RS06740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DB34_RS06740	COG2755	lipolytic protein G-D-S-L family
DB34_RS06765	COG1054	Belongs to the UPF0176 family
DB34_RS06935	COG1959	2 iron, 2 sulfur cluster binding
DB34_RS06940	COG4221	oxidoreductase activity
DB34_RS06945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DB34_RS06960	COG1607	acyl-coa hydrolase
DB34_RS06995	COG3293	Transposase
DB34_RS07035	COG0306	phosphate transporter
DB34_RS07045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DB34_RS07050	COG0022	dehydrogenase e1 component
DB34_RS07060	COG0071	Belongs to the small heat shock protein (HSP20) family
DB34_RS07075	COG1252	NADH dehydrogenase
DB34_RS07085	COG0523	cobalamin synthesis protein
DB34_RS07095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DB34_RS07105	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DB34_RS07110	COG0596	Alpha beta hydrolase
DB34_RS07125	COG1297	OPT oligopeptide transporter protein
DB34_RS07155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DB34_RS07170	COG0469	pyruvate kinase activity
DB34_RS07190	COG1217	gtp-binding protein TYPA
DB34_RS07200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DB34_RS07210	COG0492	ferredoxin-NADP+ reductase activity
DB34_RS07215	COG0538	isocitrate dehydrogenase activity
DB34_RS07255	COG4993	Dehydrogenase
DB34_RS07270	COG0481	GTPase activity
DB34_RS07275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DB34_RS07280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DB34_RS07280	COG2813	Specifically methylates the guanine in position
DB34_RS07285	COG0513	Belongs to the DEAD box helicase family
DB34_RS07310	COG1758	RNA polymerase activity
DB34_RS07315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DB34_RS07320	COG0736	holo-[acyl-carrier-protein] synthase activity
DB34_RS07325	COG0681	Belongs to the peptidase S26 family
DB34_RS07330	COG0571	ribonuclease III activity
DB34_RS07335	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DB34_RS07340	COG0528	UMP kinase activity
DB34_RS07345	COG0233	cytoplasmic translational termination
DB34_RS07350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DB34_RS07360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DB34_RS07365	COG0750	zinc metalloprotease
DB34_RS07380	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DB34_RS07385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DB34_RS07390	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DB34_RS07395	COG3494	Protein of unknown function (DUF1009)
DB34_RS07400	COG0346	lactoylglutathione lyase activity
DB34_RS07410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DB34_RS07415	COG0594	ribonuclease P activity
DB34_RS07420	COG0706	membrane insertase activity
DB34_RS07425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DB34_RS07430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DB34_RS07435	COG2171	N-acyltransferase activity
DB34_RS07440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB34_RS07450	COG0101	tRNA pseudouridine synthase activity
DB34_RS07455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DB34_RS07460	COG0242	peptide deformylase activity
DB34_RS07475	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DB34_RS07490	COG1137	ATPase activity
DB34_RS07505	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DB34_RS07505	COG0517	IMP dehydrogenase activity
DB34_RS07515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DB34_RS07530	COG0194	GDP metabolic process
DB34_RS07535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DB34_RS07535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DB34_RS07540	COG2942	2-epimerase
DB34_RS07545	COG0305	Participates in initiation and elongation during chromosome replication
DB34_RS07555	COG1196	nuclear chromosome segregation
DB34_RS07555	COG3264	Mechanosensitive ion channel
DB34_RS07560	COG1127	ABC transporter
DB34_RS07565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DB34_RS07605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DB34_RS07620	COG1113	amino acid transport
DB34_RS07630	COG0506	proline dehydrogenase activity
DB34_RS07630	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DB34_RS07630	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DB34_RS07645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DB34_RS07675	COG2096	Adenosyltransferase
DB34_RS07700	COG0009	L-threonylcarbamoyladenylate synthase
DB34_RS07710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DB34_RS07720	COG0656	L-ascorbic acid biosynthetic process
DB34_RS07730	COG1643	Atp-dependent helicase
DB34_RS07750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DB34_RS07755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DB34_RS07775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DB34_RS07780	COG0235	Class ii aldolase
DB34_RS07785	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DB34_RS07790	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DB34_RS07795	COG0196	riboflavin kinase activity
DB34_RS07800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DB34_RS07805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DB34_RS07815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DB34_RS07825	COG5006	permease, DMT superfamily
DB34_RS07830	COG0187	DNA topoisomerase II activity
DB34_RS07845	COG1959	2 iron, 2 sulfur cluster binding
DB34_RS07850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DB34_RS07855	COG2885	chlorophyll binding
DB34_RS07855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DB34_RS07865	COG0793	Belongs to the peptidase S41A family
DB34_RS07870	COG0557	exoribonuclease II activity
DB34_RS07875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DB34_RS07880	COG0758	DNA mediated transformation
DB34_RS07885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DB34_RS07890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DB34_RS07895	COG0540	Belongs to the ATCase OTCase family
DB34_RS07900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DB34_RS07905	COG2333	competence protein COMEC
DB34_RS07905	COG0658	competence protein
DB34_RS07910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DB34_RS07915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DB34_RS07925	COG0508	dehydrogenase complex catalyzes the overall conversion of
DB34_RS07945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DB34_RS07960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DB34_RS07995	COG3260	NADH ubiquinone oxidoreductase 20
DB34_RS08000	COG1183	phosphatidylcholine synthase activity
DB34_RS08005	COG0688	phosphatidylethanolamine metabolic process
DB34_RS08010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DB34_RS08020	COG2885	chlorophyll binding
DB34_RS08020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DB34_RS08025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DB34_RS08035	COG4974	Belongs to the 'phage' integrase family
DB34_RS08040	COG0825	malonyl-CoA metabolic process
DB34_RS08045	COG1058	Belongs to the CinA family
DB34_RS08045	COG1546	Belongs to the CinA family
DB34_RS08065	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DB34_RS08070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DB34_RS08075	COG0181	hydroxymethylbilane synthase activity
DB34_RS08085	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DB34_RS08090	COG0406	alpha-ribazole phosphatase activity
DB34_RS08100	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DB34_RS08120	COG0408	coproporphyrinogen oxidase activity
DB34_RS08125	COG2857	Cytochrome c1
DB34_RS08125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DB34_RS08130	COG2857	Cytochrome c1
DB34_RS08130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DB34_RS08135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DB34_RS08145	COG3293	Transposase
DB34_RS08165	COG0778	Nitroreductase
DB34_RS08180	COG3547	Transposase (IS116 IS110 IS902 family)
DB34_RS08225	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DB34_RS08230	COG1902	pentaerythritol trinitrate reductase activity
DB34_RS08235	COG0640	Transcriptional regulator
DB34_RS08245	COG3591	Belongs to the peptidase S1B family
DB34_RS08250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DB34_RS08260	COG0019	diaminopimelate decarboxylase activity
DB34_RS08265	COG0165	Argininosuccinate lyase
DB34_RS08280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DB34_RS08285	COG0237	dephospho-CoA kinase activity
DB34_RS08290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DB34_RS08310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DB34_RS08320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DB34_RS08325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DB34_RS08335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DB34_RS08340	COG0248	Ppx GppA phosphatase
DB34_RS08355	COG1121	(ABC) transporter
DB34_RS08380	COG1289	transmembrane transporter activity
DB34_RS08385	COG1289	transmembrane transporter activity
DB34_RS08405	COG3088	subunit of a heme lyase
DB34_RS08410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DB34_RS08415	COG1138	Cytochrome C-type biogenesis protein
DB34_RS08420	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DB34_RS08425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DB34_RS08460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DB34_RS08490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DB34_RS08505	COG3293	Transposase
DB34_RS08515	COG3293	Transposase
DB34_RS08520	COG0477	Major facilitator Superfamily
DB34_RS08555	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DB34_RS08560	COG0081	regulation of translation
DB34_RS08565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DB34_RS08570	COG0222	ribosome binding
DB34_RS08575	COG0085	RNA polymerase activity
DB34_RS08580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DB34_RS08585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DB34_RS08590	COG0049	tRNA binding
DB34_RS08595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DB34_RS08600	COG0051	transcription antitermination factor activity, RNA binding
DB34_RS08605	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DB34_RS08610	COG0088	Forms part of the polypeptide exit tunnel
DB34_RS08615	COG0089	rRNA binding
DB34_RS08620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DB34_RS08625	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DB34_RS08630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DB34_RS08635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DB34_RS08640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DB34_RS08645	COG0255	Belongs to the universal ribosomal protein uL29 family
DB34_RS08650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DB34_RS08655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DB34_RS08660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DB34_RS08665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DB34_RS08670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DB34_RS08675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DB34_RS08680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DB34_RS08685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DB34_RS08690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DB34_RS08695	COG1841	ribosomal large subunit assembly
DB34_RS08700	COG0200	Binds to the 23S rRNA
DB34_RS08710	COG0563	adenylate kinase activity
DB34_RS08715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DB34_RS08720	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DB34_RS08725	COG0202	RNA polymerase activity
DB34_RS08730	COG0203	ribosomal protein L17
DB34_RS08740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DB34_RS08745	COG1116	anion transmembrane transporter activity
DB34_RS08765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DB34_RS08770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DB34_RS08775	COG0477	Major facilitator Superfamily
DB34_RS08780	COG3237	CsbD-like
DB34_RS08785	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DB34_RS08790	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DB34_RS08815	COG0714	Associated with various cellular activities
DB34_RS08825	COG0617	tRNA 3'-terminal CCA addition
DB34_RS08830	COG1132	(ABC) transporter
DB34_RS08840	COG2814	Major facilitator Superfamily
DB34_RS08845	COG1051	belongs to the nudix hydrolase family
DB34_RS08855	COG0793	Belongs to the peptidase S41A family
DB34_RS08865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DB34_RS08870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DB34_RS08875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DB34_RS08880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DB34_RS08885	COG0505	Belongs to the CarA family
DB34_RS08895	COG0358	DNA primase activity
DB34_RS08900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DB34_RS08910	COG0360	Binds together with S18 to 16S ribosomal RNA
DB34_RS08915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DB34_RS08920	COG0359	binds to the 23S rRNA
DB34_RS08925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DB34_RS08930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DB34_RS08940	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DB34_RS08960	COG1132	(ABC) transporter
DB34_RS08965	COG1802	Transcriptional regulator
DB34_RS08970	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DB34_RS08980	COG0850	regulation of cytokinetic process
DB34_RS08990	COG2081	HI0933 family
DB34_RS08995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DB34_RS09005	COG0457	Tetratricopeptide repeat
DB34_RS09005	COG0859	PFAM glycosyl transferase family 9
DB34_RS09010	COG1329	Transcriptional regulator
DB34_RS09015	COG3781	membrane
DB34_RS09020	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DB34_RS09035	COG2884	Cell division ATP-binding protein ftsE
DB34_RS09060	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DB34_RS09065	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DB34_RS09085	COG2010	Cytochrome c
DB34_RS09085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DB34_RS09090	COG0246	Mannitol dehydrogenase
DB34_RS09095	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DB34_RS09100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DB34_RS09105	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DB34_RS09110	COG0072	phenylalanine-tRNA ligase activity
DB34_RS09110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DB34_RS09120	COG0747	negative chemotaxis
DB34_RS09140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DB34_RS09155	COG0473	3-isopropylmalate dehydrogenase activity
DB34_RS09160	COG0006	proline dipeptidase activity
DB34_RS09165	COG2264	protein methyltransferase activity
DB34_RS09170	COG0210	DNA helicase
DB34_RS09180	COG2003	Belongs to the UPF0758 family
DB34_RS09185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DB34_RS09210	COG0071	Belongs to the small heat shock protein (HSP20) family
DB34_RS09215	COG0254	rRNA binding
DB34_RS09220	COG1970	mechanosensitive ion channel activity
DB34_RS09230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DB34_RS09235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DB34_RS09250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DB34_RS09250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DB34_RS09255	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DB34_RS09265	COG0142	geranyltranstransferase activity
DB34_RS09270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DB34_RS09275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DB34_RS09290	COG2062	phosphohistidine phosphatase, SixA
DB34_RS09295	COG1605	Chorismate mutase
DB34_RS09295	COG0287	Prephenate dehydrogenase
DB34_RS09320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DB34_RS09330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DB34_RS09340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DB34_RS09350	COG0729	surface antigen
DB34_RS09370	COG0322	excinuclease ABC activity
DB34_RS09385	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DB34_RS09390	COG0314	molybdopterin synthase activity
DB34_RS09395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DB34_RS09400	COG0156	8-amino-7-oxononanoate synthase activity
DB34_RS09410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DB34_RS09410	COG4106	trans-aconitate 2-methyltransferase activity
DB34_RS09415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DB34_RS09420	COG0303	'Molybdopterin
DB34_RS09425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DB34_RS09435	COG0148	phosphopyruvate hydratase activity
DB34_RS09455	COG2022	thiamine diphosphate biosynthetic process
DB34_RS09470	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DB34_RS09475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DB34_RS09490	COG0076	glutamate decarboxylase activity
DB34_RS09505	COG0484	heat shock protein binding
DB34_RS09510	COG0271	Belongs to the BolA IbaG family
DB34_RS09520	COG0321	lipoyl(octanoyl) transferase activity
DB34_RS09540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DB34_RS09545	COG2226	methyltransferase
DB34_RS09570	COG2706	6-phosphogluconolactonase activity
DB34_RS09575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DB34_RS09580	COG0527	aspartate kinase activity
DB34_RS09585	COG2070	2-Nitropropane dioxygenase
DB34_RS09595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DB34_RS09600	COG0124	histidyl-tRNA synthetase
DB34_RS09605	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DB34_RS09615	COG2890	protein-(glutamine-N5) methyltransferase activity
DB34_RS09635	COG1968	undecaprenyl-diphosphatase activity
DB34_RS09640	COG0531	amino acid
DB34_RS09650	COG0586	Pfam SNARE associated Golgi protein
DB34_RS09655	COG2951	lytic endotransglycosylase activity
DB34_RS09665	COG1686	Belongs to the peptidase S11 family
DB34_RS09670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DB34_RS09685	COG0084	hydrolase, TatD family'
DB34_RS09690	COG1234	tRNA 3'-trailer cleavage
DB34_RS09700	COG0259	pyridoxamine-phosphate oxidase activity
DB34_RS09705	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DB34_RS09710	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DB34_RS09715	COG1764	response to oxidative stress
DB34_RS09720	COG0579	oxidoreductase
DB34_RS09730	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DB34_RS09735	COG0602	queuosine metabolic process
DB34_RS09740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DB34_RS09750	COG0175	sulfate reduction
DB34_RS09755	COG0175	sulfate reduction
DB34_RS09770	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DB34_RS09780	COG1519	Transferase
DB34_RS09785	COG1663	tetraacyldisaccharide 4'-kinase activity
DB34_RS09805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DB34_RS09810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DB34_RS09815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DB34_RS09825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DB34_RS09860	COG1278	Cold shock
DB34_RS09865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DB34_RS09870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DB34_RS09875	COG1605	Chorismate mutase
DB34_RS09875	COG0077	Prephenate dehydratase
DB34_RS09880	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DB34_RS09885	COG3474	cytochrome
DB34_RS09895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DB34_RS09900	COG0606	chelatase, subunit chli
DB34_RS09905	COG0626	cystathionine gamma-synthase activity
DB34_RS09910	COG2897	thiosulfate sulfurtransferase activity
DB34_RS09915	COG0628	permease
DB34_RS09925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DB34_RS09930	COG0792	nuclease activity
DB34_RS09940	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DB34_RS09945	COG0271	Belongs to the BolA IbaG family
DB34_RS09950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DB34_RS09955	COG0047	phosphoribosylformylglycinamidine synthase activity
DB34_RS09965	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DB34_RS09970	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DB34_RS09975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DB34_RS09980	COG0861	Integral membrane protein TerC family
DB34_RS09995	COG1546	Belongs to the CinA family
DB34_RS10010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DB34_RS10015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DB34_RS10020	COG0508	dehydrogenase complex catalyzes the overall conversion of
DB34_RS10025	COG0022	dehydrogenase e1 component
DB34_RS10025	COG0508	dehydrogenase complex catalyzes the overall conversion of
DB34_RS10030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DB34_RS10035	COG0315	cyclic pyranopterin monophosphate synthase activity
DB34_RS10040	COG0134	indole-3-glycerol-phosphate synthase activity
DB34_RS10045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DB34_RS10055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DB34_RS10065	COG0149	triose-phosphate isomerase activity
DB34_RS10075	COG0504	CTP synthase activity
DB34_RS10080	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DB34_RS10090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DB34_RS10100	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DB34_RS10105	COG0268	Binds directly to 16S ribosomal RNA
DB34_RS10110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DB34_RS10115	COG2226	methyltransferase
DB34_RS10120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DB34_RS10125	COG0756	dUTP diphosphatase activity
DB34_RS10130	COG1176	ABC-type spermidine putrescine transport system, permease component I
DB34_RS10135	COG1116	anion transmembrane transporter activity
DB34_RS10140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DB34_RS10145	COG0525	valine-tRNA ligase activity
DB34_RS10160	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DB34_RS10180	COG1028	Short-chain dehydrogenase reductase Sdr
DB34_RS10185	COG0456	acetyltransferase
DB34_RS10190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DB34_RS10195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DB34_RS10200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DB34_RS10210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DB34_RS10215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DB34_RS10225	COG1349	DNA-binding transcription factor activity
DB34_RS10240	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DB34_RS10245	COG4988	ABC transporter
DB34_RS10270	COG0784	Response regulator, receiver
DB34_RS10275	COG0488	(ABC) transporter
DB34_RS10290	COG2824	Alkylphosphonate utilization operon protein PhnA
DB34_RS10295	COG0814	amino acid
DB34_RS10305	COG0384	phenazine biosynthesis protein PhzF
DB34_RS10325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DB34_RS10325	COG1116	anion transmembrane transporter activity
DB34_RS10355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DB34_RS10380	COG3293	Transposase
DB34_RS10390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DB34_RS10400	COG2233	PERMEase
DB34_RS10405	COG2351	hydroxyisourate hydrolase activity
DB34_RS10420	COG2072	flavoprotein involved in K transport
DB34_RS10450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DB34_RS10455	COG0842	Transport permease protein
DB34_RS10455	COG1129	ABC transporter
DB34_RS10460	COG0842	Transport permease protein
DB34_RS10485	COG3293	Transposase
DB34_RS10495	COG2855	membrane
DB34_RS10505	COG1657	PFAM Prenyltransferase squalene oxidase
DB34_RS10525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DB34_RS10530	COG1012	belongs to the aldehyde dehydrogenase family
DB34_RS10535	COG1902	pentaerythritol trinitrate reductase activity
DB34_RS10540	COG1733	regulation of RNA biosynthetic process
DB34_RS10545	COG0753	catalase activity
DB34_RS10560	COG3459	Glycosyltransferase 36 associated
DB34_RS10585	COG4773	Receptor
DB34_RS10625	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DB34_RS10640	COG3293	Transposase
DB34_RS10665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DB34_RS10680	COG0210	DNA helicase
DB34_RS10700	COG1960	acyl-CoA dehydrogenase activity
DB34_RS10720	COG1231	oxidoreductase activity
DB34_RS10775	COG0625	glutathione transferase activity
DB34_RS10805	COG4977	sequence-specific DNA binding
DB34_RS10855	COG1301	dicarboxylic acid transport
DB34_RS10860	COG0500	methyltransferase
DB34_RS10865	COG2999	glutathione oxidoreductase activity
DB34_RS10870	COG2814	Major facilitator Superfamily
DB34_RS10875	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DB34_RS10925	COG0114	fumarate hydratase activity
DB34_RS10955	COG3547	Transposase (IS116 IS110 IS902 family)
DB34_RS10980	COG3293	Transposase
DB34_RS11005	COG0628	permease
DB34_RS11030	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DB34_RS11030	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DB34_RS11030	COG1013	pyruvate-flavodoxin oxidoreductase activity
DB34_RS11030	COG0674	pyruvate-flavodoxin oxidoreductase activity
DB34_RS11035	COG0493	'glutamate synthase
DB34_RS11050	COG1971	Probably functions as a manganese efflux pump
DB34_RS11060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DB34_RS11075	COG3293	Transposase
DB34_RS11085	COG0303	'Molybdopterin
DB34_RS11090	COG3058	Necessary for formate dehydrogenase activity
DB34_RS11095	COG2864	formate dehydrogenase
DB34_RS11100	COG0437	4 iron, 4 sulfur cluster binding
DB34_RS11105	COG3383	formate dehydrogenase (NAD+) activity
DB34_RS11105	COG0243	molybdopterin cofactor binding
DB34_RS11115	COG0248	Ppx GppA phosphatase
DB34_RS11120	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DB34_RS11125	COG1940	carbohydrate kinase activity
DB34_RS11130	COG0425	Belongs to the sulfur carrier protein TusA family
DB34_RS11135	COG1722	exodeoxyribonuclease VII activity
DB34_RS11140	COG0142	geranyltranstransferase activity
DB34_RS11145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DB34_RS11150	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DB34_RS11160	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DB34_RS11165	COG0137	argininosuccinate synthase activity
DB34_RS11170	COG0545	Peptidyl-prolyl cis-trans isomerase
DB34_RS11180	COG0180	Tryptophanyl-tRNA synthetase
DB34_RS11205	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DB34_RS11215	COG1914	H( )-stimulated, divalent metal cation uptake system
DB34_RS11385	COG3293	Transposase
DB34_RS11485	COG1783	phage Terminase large subunit
DB34_RS11565	COG0629	single-stranded DNA binding
DB34_RS11585	COG1396	sequence-specific DNA binding
DB34_RS11675	COG0745	RESPONSE REGULATOR receiver
DB34_RS11690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DB34_RS11690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DB34_RS11705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DB34_RS11720	COG4608	Belongs to the ABC transporter superfamily
DB34_RS11725	COG2070	2-Nitropropane dioxygenase
DB34_RS11730	COG0671	phosphoesterase, PA-phosphatase related
DB34_RS11745	COG3511	phospholipase C
DB34_RS11810	COG1695	Transcriptional regulator
DB34_RS11825	COG1289	transmembrane transporter activity
DB34_RS11835	COG1032	radical SAM domain protein
DB34_RS11850	COG0668	transmembrane transport
DB34_RS11865	COG1294	oxidase, subunit
DB34_RS11870	COG1271	oxidase subunit
DB34_RS11875	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DB34_RS11880	COG4988	ABC transporter
DB34_RS11885	COG3293	Transposase
DB34_RS11895	COG3128	pkhd-type hydroxylase
DB34_RS11900	COG4774	siderophore transport
DB34_RS11925	COG0252	asparaginase activity
DB34_RS11935	COG2985	domain, Protein
DB34_RS11940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DB34_RS11965	COG0488	(ABC) transporter
DB34_RS11970	COG0583	DNA-binding transcription factor activity
DB34_RS12005	COG3547	Transposase (IS116 IS110 IS902 family)
DB34_RS12020	COG1064	alcohol dehydrogenase
DB34_RS12035	COG2814	Major facilitator Superfamily
DB34_RS12045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DB34_RS12050	COG1834	amidinotransferase
DB34_RS12060	COG0765	amino acid transport
DB34_RS12065	COG1126	abc transporter atp-binding protein
DB34_RS12130	COG0318	PFAM AMP-dependent synthetase and ligase
DB34_RS12140	COG0156	8-amino-7-oxononanoate synthase activity
DB34_RS12155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DB34_RS12180	COG0546	phosphoglycolate phosphatase activity
DB34_RS12185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DB34_RS12190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DB34_RS12205	COG0386	Belongs to the glutathione peroxidase family
DB34_RS12210	COG1136	(ABC) transporter
DB34_RS12220	COG0442	prolyl-tRNA aminoacylation
DB34_RS12230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DB34_RS12240	COG1007	ATP synthesis coupled electron transport
DB34_RS12250	COG0713	ATP synthesis coupled electron transport
DB34_RS12260	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DB34_RS12265	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DB34_RS12270	COG1034	ATP synthesis coupled electron transport
DB34_RS12280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DB34_RS12285	COG0649	NAD binding
DB34_RS12290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DB34_RS12295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DB34_RS12320	COG0776	regulation of translation
DB34_RS12330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DB34_RS12335	COG0740	serine-type endopeptidase activity
DB34_RS12340	COG0544	peptidyl-prolyl cis-trans isomerase activity
DB34_RS12350	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DB34_RS12350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DB34_RS12360	COG0513	Belongs to the DEAD box helicase family
DB34_RS12365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DB34_RS12370	COG0316	Belongs to the HesB IscA family
DB34_RS12375	COG2151	metal-sulfur cluster biosynthetic enzyme
DB34_RS12385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DB34_RS12390	COG0719	Fe-S assembly protein
DB34_RS12395	COG0396	ATPase activity
DB34_RS12400	COG0719	Fe-S assembly protein
DB34_RS12410	COG2733	membrane
DB34_RS12415	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DB34_RS12425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DB34_RS12430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DB34_RS12440	COG5265	(ABC) transporter
DB34_RS12450	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DB34_RS12455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DB34_RS12480	COG0612	Peptidase, M16
DB34_RS12485	COG0312	modulator of DNA gyrase
DB34_RS12500	COG0109	protoheme IX farnesyltransferase activity
DB34_RS12510	COG2226	methyltransferase
DB34_RS12530	COG1522	sequence-specific DNA binding
DB34_RS12535	COG0492	ferredoxin-NADP+ reductase activity
DB34_RS12540	COG0583	DNA-binding transcription factor activity
DB34_RS12545	COG4957	zinc ion binding
DB34_RS12550	COG0776	regulation of translation
DB34_RS12565	COG0628	permease
DB34_RS12580	COG0776	regulation of translation
DB34_RS12585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DB34_RS12590	COG0416	fatty acid biosynthetic process
DB34_RS12595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DB34_RS12615	COG0745	RESPONSE REGULATOR receiver
DB34_RS12620	COG1846	Transcriptional regulator
DB34_RS12630	COG0242	peptide deformylase activity
DB34_RS12635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DB34_RS12640	COG0473	3-isopropylmalate dehydrogenase activity
DB34_RS12645	COG0066	3-isopropylmalate dehydratase activity
DB34_RS12650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DB34_RS12655	COG0335	large ribosomal subunit rRNA binding
DB34_RS12660	COG0336	Belongs to the RNA methyltransferase TrmD family
DB34_RS12665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DB34_RS12670	COG0228	four-way junction DNA binding
DB34_RS12695	COG0564	pseudouridine synthase activity
DB34_RS12700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DB34_RS12720	COG3572	ergothioneine biosynthetic process
DB34_RS12725	COG2814	Major facilitator Superfamily
DB34_RS12730	COG1160	GTP binding
DB34_RS12755	COG0438	transferase activity, transferring glycosyl groups
DB34_RS12770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DB34_RS12775	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DB34_RS12780	COG0659	secondary active sulfate transmembrane transporter activity
DB34_RS12810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DB34_RS12820	COG1051	belongs to the nudix hydrolase family
DB34_RS12825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DB34_RS12830	COG1923	regulation of RNA biosynthetic process
DB34_RS12835	COG2204	response regulator
DB34_RS12860	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DB34_RS12860	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DB34_RS12865	COG0463	Glycosyl transferase, family 2
DB34_RS12920	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DB34_RS12930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DB34_RS12945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DB34_RS12955	COG0347	Belongs to the P(II) protein family
DB34_RS12965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DB34_RS12970	COG0586	Pfam SNARE associated Golgi protein
DB34_RS13015	COG3547	Transposase (IS116 IS110 IS902 family)
DB34_RS13095	COG4381	Mu-like prophage protein gp46
DB34_RS13130	COG4386	tail sheath protein
DB34_RS13170	COG0616	signal peptide processing
DB34_RS13215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DB34_RS13350	COG0582	viral genome integration into host DNA
DB34_RS13360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DB34_RS13365	COG0483	inositol monophosphate 1-phosphatase activity
DB34_RS13370	COG1199	ATP-dependent helicase activity
DB34_RS13375	COG1278	Cold shock
DB34_RS13380	COG0412	Dienelactone hydrolase
DB34_RS13385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DB34_RS13390	COG0459	protein refolding
DB34_RS13430	COG3293	Transposase