locus-tag	class	description
CJF59_RS00100	COG4626	Terminase
CJF59_RS00100	COG1802	Transcriptional regulator
CJF59_RS00220	COG0582	viral genome integration into host DNA
CJF59_RS00235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJF59_RS00240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CJF59_RS00245	COG0445	tRNA wobble uridine modification
CJF59_RS00250	COG0357	Ribosomal RNA small subunit methyltransferase G
CJF59_RS00290	COG0778	Nitroreductase
CJF59_RS00300	COG0140	phosphoribosyl-ATP diphosphatase activity
CJF59_RS00305	COG0107	imidazoleglycerol-phosphate synthase activity
CJF59_RS00310	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CJF59_RS00315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CJF59_RS00320	COG0131	Imidazoleglycerol-phosphate dehydratase
CJF59_RS00335	COG1216	Glycosyl transferase, family 2
CJF59_RS00355	COG0776	regulation of translation
CJF59_RS00390	COG0484	heat shock protein binding
CJF59_RS00415	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CJF59_RS00420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJF59_RS00425	COG0653	protein targeting
CJF59_RS00430	COG0217	transcriptional regulatory protein
CJF59_RS00435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CJF59_RS00440	COG0632	four-way junction helicase activity
CJF59_RS00445	COG2255	four-way junction helicase activity
CJF59_RS00450	COG0824	Thioesterase
CJF59_RS00460	COG0848	biopolymer transport protein
CJF59_RS00470	COG0823	Involved in the tonB-independent uptake of proteins
CJF59_RS00475	COG2885	chlorophyll binding
CJF59_RS00485	COG0037	tRNA processing
CJF59_RS00490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJF59_RS00500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJF59_RS00505	COG0745	RESPONSE REGULATOR receiver
CJF59_RS00510	COG0802	atpase or kinase
CJF59_RS00515	COG2887	Belongs to the helicase family. UvrD subfamily
CJF59_RS00530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CJF59_RS00535	COG0285	dihydrofolate synthase activity
CJF59_RS00545	COG0215	cysteine-tRNA ligase activity
CJF59_RS00555	COG2945	thiolester hydrolase activity
CJF59_RS00560	COG1104	cysteine desulfurase activity
CJF59_RS00565	COG1104	cysteine desulfurase activity
CJF59_RS00575	COG0482	sulfurtransferase activity
CJF59_RS00590	COG0564	pseudouridine synthase activity
CJF59_RS00595	COG1674	ftsk spoiiie
CJF59_RS00605	COG1091	dTDP-4-dehydrorhamnose reductase activity
CJF59_RS00610	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CJF59_RS00630	COG0406	alpha-ribazole phosphatase activity
CJF59_RS00635	COG0312	modulator of DNA gyrase
CJF59_RS00640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJF59_RS00670	COG0629	single-stranded DNA binding
CJF59_RS00675	COG0742	ribosomal rna small subunit methyltransferase
CJF59_RS00680	COG1187	pseudouridine synthase activity
CJF59_RS00685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CJF59_RS00690	COG0590	tRNA wobble adenosine to inosine editing
CJF59_RS00700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF59_RS00710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJF59_RS00870	COG0495	leucyl-tRNA aminoacylation
CJF59_RS00895	COG1194	a g-specific adenine glycosylase
CJF59_RS00900	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CJF59_RS00910	COG1132	(ABC) transporter
CJF59_RS00920	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJF59_RS00925	COG0154	amidase activity
CJF59_RS00930	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJF59_RS00935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CJF59_RS00945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CJF59_RS00980	COG0672	)-iron permease
CJF59_RS00995	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CJF59_RS01000	COG2814	Major facilitator Superfamily
CJF59_RS01005	COG0439	Biotin carboxylase
CJF59_RS01010	COG0511	ligase activity, forming carbon-carbon bonds
CJF59_RS01015	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJF59_RS01025	COG1295	ribonuclease BN
CJF59_RS01045	COG4133	protoheme IX ABC transporter activity
CJF59_RS01055	COG1126	abc transporter atp-binding protein
CJF59_RS01060	COG0765	amino acid transport
CJF59_RS01075	COG0542	response to heat
CJF59_RS01085	COG0779	Required for maturation of 30S ribosomal subunits
CJF59_RS01100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CJF59_RS01105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CJF59_RS01110	COG1522	sequence-specific DNA binding
CJF59_RS01115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJF59_RS01120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJF59_RS01135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CJF59_RS01135	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CJF59_RS01150	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CJF59_RS01165	COG0489	protein tyrosine kinase activity
CJF59_RS01200	COG0129	dihydroxy-acid dehydratase activity
CJF59_RS01205	COG0573	inorganic phosphate transmembrane transporter activity
CJF59_RS01210	COG0581	inorganic phosphate transmembrane transporter activity
CJF59_RS01215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CJF59_RS01220	COG0704	Plays a role in the regulation of phosphate uptake
CJF59_RS01235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CJF59_RS01255	COG0513	Belongs to the DEAD box helicase family
CJF59_RS01270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJF59_RS01275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJF59_RS01280	COG0552	protein localization to endoplasmic reticulum
CJF59_RS01290	COG0356	it plays a direct role in the translocation of protons across the membrane
CJF59_RS01295	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJF59_RS01300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJF59_RS01305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJF59_RS01310	COG0463	Glycosyl transferase, family 2
CJF59_RS01315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CJF59_RS01325	COG2995	paraquat-inducible protein a
CJF59_RS01330	COG3008	intermembrane lipid transfer
CJF59_RS01340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CJF59_RS01355	COG0646	methionine synthase
CJF59_RS01355	COG1410	methionine synthase
CJF59_RS01365	COG2274	protein secretion by the type I secretion system
CJF59_RS01400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CJF59_RS01400	COG3008	intermembrane lipid transfer
CJF59_RS01405	COG1127	ABC transporter
CJF59_RS01410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJF59_RS01415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CJF59_RS01420	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CJF59_RS01425	COG1185	polyribonucleotide nucleotidyltransferase activity
CJF59_RS01440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJF59_RS01445	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CJF59_RS01505	COG1199	ATP-dependent helicase activity
CJF59_RS01505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CJF59_RS01595	COG0740	serine-type endopeptidase activity
CJF59_RS01710	COG0583	DNA-binding transcription factor activity
CJF59_RS01720	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CJF59_RS01725	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CJF59_RS01730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CJF59_RS01735	COG0509	glycine decarboxylation via glycine cleavage system
CJF59_RS01740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJF59_RS01740	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJF59_RS01770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF59_RS01815	COG1846	Transcriptional regulator
CJF59_RS01820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJF59_RS01825	COG2080	2 iron, 2 sulfur cluster binding
CJF59_RS01830	COG2010	Cytochrome c
CJF59_RS01830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CJF59_RS01835	COG2309	aminopeptidase activity
CJF59_RS01840	COG1335	isochorismatase
CJF59_RS01845	COG0596	Alpha beta hydrolase
CJF59_RS01850	COG3473	Maleate cis-trans isomerase
CJF59_RS01855	COG2271	Major facilitator Superfamily
CJF59_RS01910	COG0450	alkyl hydroperoxide reductase
CJF59_RS01920	COG2818	Glycosylase
CJF59_RS01930	COG1393	Belongs to the ArsC family
CJF59_RS01955	COG3961	Belongs to the TPP enzyme family
CJF59_RS01960	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CJF59_RS01965	COG0829	nickel cation binding
CJF59_RS01970	COG0831	urea catabolic process
CJF59_RS01975	COG0832	Belongs to the urease beta subunit family
CJF59_RS01980	COG0804	urea catabolic process
CJF59_RS01985	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CJF59_RS01990	COG0830	nickel cation binding
CJF59_RS01995	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CJF59_RS02010	COG0745	RESPONSE REGULATOR receiver
CJF59_RS02015	COG5002	protein histidine kinase activity
CJF59_RS02015	COG2198	Histidine kinase
CJF59_RS02015	COG0784	Response regulator, receiver
CJF59_RS02035	COG0411	ABC transporter
CJF59_RS02055	COG2814	Major facilitator Superfamily
CJF59_RS02065	COG0583	DNA-binding transcription factor activity
CJF59_RS02090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF59_RS02115	COG2144	transferase activity, transferring acyl groups
CJF59_RS02130	COG2072	flavoprotein involved in K transport
CJF59_RS02140	COG2223	nitrite transmembrane transporter activity
CJF59_RS02160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF59_RS02170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJF59_RS02190	COG1917	Cupin 2, conserved barrel domain protein
CJF59_RS02190	COG2207	Transcriptional regulator
CJF59_RS02195	COG2375	cellular response to nickel ion
CJF59_RS02195	COG1132	(ABC) transporter
CJF59_RS02200	COG1132	(ABC) transporter
CJF59_RS02240	COG0789	Transcriptional regulator
CJF59_RS02445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJF59_RS02450	COG3158	transport of potassium into the cell
CJF59_RS02460	COG1063	alcohol dehydrogenase
CJF59_RS02485	COG3265	gluconokinase activity
CJF59_RS02490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CJF59_RS02495	COG0363	glucosamine-6-phosphate deaminase activity
CJF59_RS02505	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CJF59_RS02510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJF59_RS02525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJF59_RS02540	COG1742	UPF0060 membrane protein
CJF59_RS02565	COG1496	oxidoreductase activity
CJF59_RS02575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CJF59_RS02595	COG1196	nuclear chromosome segregation
CJF59_RS02595	COG0739	heme binding
CJF59_RS02595	COG0741	lytic transglycosylase activity
CJF59_RS02600	COG2814	Major facilitator Superfamily
CJF59_RS02615	COG0519	Catalyzes the synthesis of GMP from XMP
CJF59_RS02615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJF59_RS02620	COG0582	viral genome integration into host DNA
CJF59_RS02655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CJF59_RS02685	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CJF59_RS02700	COG0735	belongs to the Fur family
CJF59_RS02715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CJF59_RS02720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CJF59_RS02725	COG1024	Enoyl-CoA hydratase
CJF59_RS02730	COG1584	GPR1 FUN34 yaaH family protein
CJF59_RS02735	COG1289	transmembrane transporter activity
CJF59_RS02760	COG1797	cobyrinic acid a,c-diamide synthase activity
CJF59_RS02775	COG1492	cobalamin metabolic process
CJF59_RS02780	COG0778	Nitroreductase
CJF59_RS02795	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CJF59_RS02800	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CJF59_RS02810	COG2814	Major facilitator Superfamily
CJF59_RS02845	COG1301	dicarboxylic acid transport
CJF59_RS02865	COG0848	biopolymer transport protein
CJF59_RS02940	COG1648	precorrin-2 dehydrogenase activity
CJF59_RS02940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJF59_RS02945	COG0277	FAD linked oxidase domain protein
CJF59_RS02955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJF59_RS02960	COG2011	ABC-type metal ion transport system permease component
CJF59_RS02970	COG3620	sequence-specific DNA binding
CJF59_RS02980	COG3145	DNA-N1-methyladenine dioxygenase activity
CJF59_RS03005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CJF59_RS03015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CJF59_RS03020	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CJF59_RS03030	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CJF59_RS03040	COG0284	orotidine-5'-phosphate decarboxylase activity
CJF59_RS03045	COG0135	phosphoribosylanthranilate isomerase activity
CJF59_RS03070	COG1113	amino acid transport
CJF59_RS03085	COG1271	oxidase subunit
CJF59_RS03090	COG1294	oxidase, subunit
CJF59_RS03105	COG0477	Major facilitator Superfamily
CJF59_RS03120	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJF59_RS03120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJF59_RS03125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJF59_RS03130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CJF59_RS03135	COG1120	ATPase activity
CJF59_RS03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJF59_RS03145	COG0564	pseudouridine synthase activity
CJF59_RS03160	COG1494	fructose-1,6-bisphosphatase
CJF59_RS03170	COG0436	Aminotransferase
CJF59_RS03180	COG0740	serine-type endopeptidase activity
CJF59_RS03190	COG0535	radical SAM domain protein
CJF59_RS03200	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CJF59_RS03205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CJF59_RS03230	COG0708	Exodeoxyribonuclease III
CJF59_RS03235	COG0316	Belongs to the HesB IscA family
CJF59_RS03240	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CJF59_RS03245	COG0018	arginyl-trna synthetase
CJF59_RS03255	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CJF59_RS03260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CJF59_RS03265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJF59_RS03270	COG0805	protein transport
CJF59_RS03275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CJF59_RS03285	COG4232	protein-disulfide reductase activity
CJF59_RS03310	COG1289	transmembrane transporter activity
CJF59_RS03315	COG0583	DNA-binding transcription factor activity
CJF59_RS03320	COG1051	belongs to the nudix hydrolase family
CJF59_RS03425	COG0741	lytic transglycosylase activity
CJF59_RS03470	COG2176	DNA-directed DNA polymerase activity
CJF59_RS03495	COG4962	Type ii secretion system protein e
CJF59_RS03500	COG3838	Conjugal transfer protein Trbc
CJF59_RS03535	COG2186	Transcriptional regulator
CJF59_RS03575	COG4774	siderophore transport
CJF59_RS03580	COG1538	Outer membrane efflux protein
CJF59_RS03590	COG2814	Major facilitator Superfamily
CJF59_RS03625	COG1562	ergosterol biosynthetic process
CJF59_RS03670	COG4774	siderophore transport
CJF59_RS03730	COG4977	sequence-specific DNA binding
CJF59_RS03735	COG2808	Putative FMN-binding domain
CJF59_RS03755	COG2197	response regulator
CJF59_RS03765	COG2084	Dehydrogenase
CJF59_RS03885	COG1045	serine acetyltransferase
CJF59_RS03890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF59_RS03895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CJF59_RS03940	COG0583	DNA-binding transcription factor activity
CJF59_RS04010	COG0583	DNA-binding transcription factor activity
CJF59_RS04020	COG0431	NADPH-dependent FMN reductase
CJF59_RS04030	COG2814	Major facilitator Superfamily
CJF59_RS04035	COG1012	belongs to the aldehyde dehydrogenase family
CJF59_RS04045	COG1252	NADH dehydrogenase
CJF59_RS04050	COG1309	transcriptional regulator
CJF59_RS04075	COG2308	Evidence 4 Homologs of previously reported genes of
CJF59_RS04090	COG0277	FAD linked oxidase domain protein
CJF59_RS04180	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CJF59_RS04190	COG0424	maF-like protein
CJF59_RS04195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJF59_RS04200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CJF59_RS04205	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CJF59_RS04210	COG1530	ribonuclease E activity
CJF59_RS04260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CJF59_RS04265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CJF59_RS04270	COG0328	RNA-DNA hybrid ribonuclease activity
CJF59_RS04305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJF59_RS04310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJF59_RS04325	COG0745	RESPONSE REGULATOR receiver
CJF59_RS04335	COG0488	(ABC) transporter
CJF59_RS04340	COG0105	UTP biosynthetic process
CJF59_RS04345	COG1032	radical SAM domain protein
CJF59_RS04350	COG3161	chorismate lyase activity
CJF59_RS04370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJF59_RS04375	COG0436	Aminotransferase
CJF59_RS04380	COG0436	Aminotransferase
CJF59_RS04395	COG0251	oxidation-reduction process
CJF59_RS04400	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CJF59_RS04435	COG0052	Belongs to the universal ribosomal protein uS2 family
CJF59_RS04440	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CJF59_RS04445	COG1381	Involved in DNA repair and RecF pathway recombination
CJF59_RS04450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJF59_RS04455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CJF59_RS04460	COG0113	porphobilinogen synthase activity
CJF59_RS04465	COG0531	amino acid
CJF59_RS04470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CJF59_RS04490	COG0513	Belongs to the DEAD box helicase family
CJF59_RS04505	COG0560	Phosphoserine phosphatase
CJF59_RS04510	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJF59_RS04515	COG0028	Belongs to the TPP enzyme family
CJF59_RS04525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CJF59_RS04535	COG2132	Multicopper oxidase
CJF59_RS04545	COG2217	Heavy metal translocating P-type atpase
CJF59_RS04555	COG1335	isochorismatase
CJF59_RS04560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJF59_RS04575	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CJF59_RS04595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CJF59_RS04600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJF59_RS04600	COG0574	Belongs to the PEP-utilizing enzyme family
CJF59_RS04605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CJF59_RS04610	COG0497	DNA recombination
CJF59_RS04615	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CJF59_RS04620	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CJF59_RS04630	COG0849	cell division
CJF59_RS04635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CJF59_RS04640	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJF59_RS04645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJF59_RS04650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJF59_RS04655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJF59_RS04665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJF59_RS04670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJF59_RS04680	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CJF59_RS04695	COG0275	rRNA processing
CJF59_RS04700	COG2001	Belongs to the MraZ family
CJF59_RS04710	COG0657	acetylesterase activity
CJF59_RS04720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CJF59_RS04725	COG3750	Belongs to the UPF0335 family
CJF59_RS04735	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CJF59_RS04740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CJF59_RS04745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CJF59_RS04750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJF59_RS04810	COG2252	PERMEase
CJF59_RS04830	COG0723	plastoquinol--plastocyanin reductase activity
CJF59_RS04835	COG2857	Cytochrome c1
CJF59_RS04835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJF59_RS04840	COG2857	Cytochrome c1
CJF59_RS04840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJF59_RS04850	COG0307	riboflavin synthase, alpha
CJF59_RS04855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF59_RS04855	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF59_RS04860	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CJF59_RS04890	COG1566	PFAM secretion protein HlyD family protein
CJF59_RS04920	COG0521	Mo-molybdopterin cofactor biosynthetic process
CJF59_RS04930	COG0302	gtp cyclohydrolase
CJF59_RS04950	COG0494	nUDIX hydrolase
CJF59_RS04965	COG1862	Preprotein translocase
CJF59_RS04975	COG4974	Belongs to the 'phage' integrase family
CJF59_RS04995	COG0004	ammonium transporteR
CJF59_RS05010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF59_RS05045	COG0459	protein refolding
CJF59_RS05050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CJF59_RS05055	COG0412	Dienelactone hydrolase
CJF59_RS05060	COG1278	Cold shock
CJF59_RS05065	COG1199	ATP-dependent helicase activity
CJF59_RS05070	COG0483	inositol monophosphate 1-phosphatase activity
CJF59_RS05075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CJF59_RS05095	COG0586	Pfam SNARE associated Golgi protein
CJF59_RS05100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJF59_RS05110	COG0347	Belongs to the P(II) protein family
CJF59_RS05115	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CJF59_RS05130	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CJF59_RS05145	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CJF59_RS05185	COG0463	Glycosyl transferase, family 2
CJF59_RS05190	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CJF59_RS05190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CJF59_RS05215	COG2204	response regulator
CJF59_RS05220	COG1923	regulation of RNA biosynthetic process
CJF59_RS05225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJF59_RS05230	COG1051	belongs to the nudix hydrolase family
CJF59_RS05240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJF59_RS05265	COG0659	secondary active sulfate transmembrane transporter activity
CJF59_RS05270	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF59_RS05275	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJF59_RS05280	COG0354	folic acid binding
CJF59_RS05285	COG0367	asparagine synthase
CJF59_RS05290	COG0438	transferase activity, transferring glycosyl groups
CJF59_RS05315	COG1160	GTP binding
CJF59_RS05320	COG2814	Major facilitator Superfamily
CJF59_RS05325	COG3572	ergothioneine biosynthetic process
CJF59_RS05345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CJF59_RS05350	COG0564	pseudouridine synthase activity
CJF59_RS05375	COG0228	four-way junction DNA binding
CJF59_RS05380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CJF59_RS05385	COG0336	Belongs to the RNA methyltransferase TrmD family
CJF59_RS05390	COG0335	large ribosomal subunit rRNA binding
CJF59_RS05395	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJF59_RS05400	COG0066	3-isopropylmalate dehydratase activity
CJF59_RS05405	COG0473	3-isopropylmalate dehydrogenase activity
CJF59_RS05410	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CJF59_RS05415	COG0242	peptide deformylase activity
CJF59_RS05425	COG1846	Transcriptional regulator
CJF59_RS05430	COG0745	RESPONSE REGULATOR receiver
CJF59_RS05450	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CJF59_RS05455	COG0416	fatty acid biosynthetic process
CJF59_RS05460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF59_RS05465	COG0776	regulation of translation
CJF59_RS05495	COG0776	regulation of translation
CJF59_RS05500	COG4957	zinc ion binding
CJF59_RS05505	COG0583	DNA-binding transcription factor activity
CJF59_RS05510	COG0492	ferredoxin-NADP+ reductase activity
CJF59_RS05515	COG1522	sequence-specific DNA binding
CJF59_RS05520	COG0463	Glycosyl transferase, family 2
CJF59_RS05540	COG2226	methyltransferase
CJF59_RS05550	COG0109	protoheme IX farnesyltransferase activity
CJF59_RS05565	COG0312	modulator of DNA gyrase
CJF59_RS05570	COG0612	Peptidase, M16
CJF59_RS05595	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CJF59_RS05600	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CJF59_RS05610	COG5265	(ABC) transporter
CJF59_RS05620	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJF59_RS05630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJF59_RS05640	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CJF59_RS05645	COG2733	membrane
CJF59_RS05655	COG0719	Fe-S assembly protein
CJF59_RS05660	COG0396	ATPase activity
CJF59_RS05665	COG0719	Fe-S assembly protein
CJF59_RS05670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CJF59_RS05680	COG2151	metal-sulfur cluster biosynthetic enzyme
CJF59_RS05685	COG0316	Belongs to the HesB IscA family
CJF59_RS05695	COG0513	Belongs to the DEAD box helicase family
CJF59_RS05705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CJF59_RS05705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CJF59_RS05715	COG0544	peptidyl-prolyl cis-trans isomerase activity
CJF59_RS05720	COG0740	serine-type endopeptidase activity
CJF59_RS05725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CJF59_RS05735	COG0776	regulation of translation
CJF59_RS05750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF59_RS05755	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF59_RS05760	COG0649	NAD binding
CJF59_RS05765	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CJF59_RS05775	COG1034	ATP synthesis coupled electron transport
CJF59_RS05780	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CJF59_RS05785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF59_RS05795	COG0713	ATP synthesis coupled electron transport
CJF59_RS05805	COG1007	ATP synthesis coupled electron transport
CJF59_RS05815	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CJF59_RS05825	COG0442	prolyl-tRNA aminoacylation
CJF59_RS05835	COG1136	(ABC) transporter
CJF59_RS05840	COG0386	Belongs to the glutathione peroxidase family
CJF59_RS05855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJF59_RS05860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CJF59_RS05865	COG0546	phosphoglycolate phosphatase activity
CJF59_RS05890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CJF59_RS05905	COG0156	8-amino-7-oxononanoate synthase activity
CJF59_RS05915	COG0318	PFAM AMP-dependent synthetase and ligase
CJF59_RS05970	COG0667	Aldo Keto reductase
CJF59_RS05975	COG0667	Aldo Keto reductase
CJF59_RS05980	COG0583	DNA-binding transcription factor activity
CJF59_RS05985	COG0655	NAD(P)H dehydrogenase (quinone) activity
CJF59_RS05995	COG2814	Major facilitator Superfamily
CJF59_RS06000	COG4221	oxidoreductase activity
CJF59_RS06005	COG2315	Protein conserved in bacteria
CJF59_RS06025	COG0789	Transcriptional regulator
CJF59_RS06030	COG1028	Short-chain dehydrogenase reductase Sdr
CJF59_RS06065	COG0583	DNA-binding transcription factor activity
CJF59_RS06075	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJF59_RS06105	COG1203	CRISPR-associated helicase, Cas3
CJF59_RS06120	COG1857	crispr-associated protein
CJF59_RS06135	COG1518	maintenance of DNA repeat elements
CJF59_RS06140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CJF59_RS06145	COG1902	pentaerythritol trinitrate reductase activity
CJF59_RS06160	COG2814	Major facilitator Superfamily
CJF59_RS06175	COG1064	alcohol dehydrogenase
CJF59_RS06195	COG0488	(ABC) transporter
CJF59_RS06210	COG2985	domain, Protein
CJF59_RS06220	COG0252	asparaginase activity
CJF59_RS06235	COG4774	siderophore transport
CJF59_RS06240	COG3128	pkhd-type hydroxylase
CJF59_RS06245	COG4988	ABC transporter
CJF59_RS06250	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CJF59_RS06255	COG1271	oxidase subunit
CJF59_RS06260	COG1294	oxidase, subunit
CJF59_RS06275	COG0668	transmembrane transport
CJF59_RS06290	COG1032	radical SAM domain protein
CJF59_RS06300	COG1695	Transcriptional regulator
CJF59_RS06320	COG3511	phospholipase C
CJF59_RS06330	COG0671	phosphoesterase, PA-phosphatase related
CJF59_RS06335	COG2070	2-Nitropropane dioxygenase
CJF59_RS06340	COG4608	Belongs to the ABC transporter superfamily
CJF59_RS06355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJF59_RS06360	COG0747	negative chemotaxis
CJF59_RS06370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CJF59_RS06370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJF59_RS06385	COG0745	RESPONSE REGULATOR receiver
CJF59_RS06400	COG0180	Tryptophanyl-tRNA synthetase
CJF59_RS06410	COG0545	Peptidyl-prolyl cis-trans isomerase
CJF59_RS06415	COG0137	argininosuccinate synthase activity
CJF59_RS06420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CJF59_RS06430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CJF59_RS06435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJF59_RS06440	COG0142	geranyltranstransferase activity
CJF59_RS06445	COG1722	exodeoxyribonuclease VII activity
CJF59_RS06450	COG0425	Belongs to the sulfur carrier protein TusA family
CJF59_RS06455	COG1940	carbohydrate kinase activity
CJF59_RS06460	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CJF59_RS06465	COG0248	Ppx GppA phosphatase
CJF59_RS06475	COG3383	formate dehydrogenase (NAD+) activity
CJF59_RS06475	COG0243	molybdopterin cofactor binding
CJF59_RS06480	COG0437	4 iron, 4 sulfur cluster binding
CJF59_RS06485	COG2864	formate dehydrogenase
CJF59_RS06490	COG3058	Necessary for formate dehydrogenase activity
CJF59_RS06495	COG0303	'Molybdopterin
CJF59_RS06500	COG1763	Mo-molybdopterin cofactor biosynthetic process
CJF59_RS06505	COG0746	molybdenum cofactor guanylyltransferase activity
CJF59_RS06510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJF59_RS06520	COG1971	Probably functions as a manganese efflux pump
CJF59_RS06530	COG0493	'glutamate synthase
CJF59_RS06535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CJF59_RS06535	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CJF59_RS06535	COG1013	pyruvate-flavodoxin oxidoreductase activity
CJF59_RS06535	COG0674	pyruvate-flavodoxin oxidoreductase activity
CJF59_RS06540	COG0167	dihydroorotate dehydrogenase activity
CJF59_RS06560	COG0628	permease
CJF59_RS06620	COG0114	fumarate hydratase activity
CJF59_RS06670	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CJF59_RS06675	COG2814	Major facilitator Superfamily
CJF59_RS06680	COG2999	glutathione oxidoreductase activity
CJF59_RS06685	COG0500	methyltransferase
CJF59_RS06690	COG1301	dicarboxylic acid transport
CJF59_RS06735	COG0640	Transcriptional regulator
CJF59_RS06745	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJF59_RS06750	COG0735	belongs to the Fur family
CJF59_RS06765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJF59_RS06770	COG0523	cobalamin synthesis protein
CJF59_RS06775	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CJF59_RS06810	COG0583	DNA-binding transcription factor activity
CJF59_RS06815	COG1309	transcriptional regulator
CJF59_RS06820	COG0667	Aldo Keto reductase
CJF59_RS06825	COG1028	Short-chain dehydrogenase reductase Sdr
CJF59_RS06835	COG1028	Short-chain dehydrogenase reductase Sdr
CJF59_RS06845	COG2814	Major facilitator Superfamily
CJF59_RS06855	COG4774	siderophore transport
CJF59_RS06865	COG0583	DNA-binding transcription factor activity
CJF59_RS06910	COG4953	penicillin-binding protein 1C
CJF59_RS06915	COG2373	Large extracellular alpha-helical protein
CJF59_RS06985	COG2175	clavaminate synthase activity
CJF59_RS06995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJF59_RS07000	COG1116	anion transmembrane transporter activity
CJF59_RS07005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJF59_RS07010	COG1191	sigma factor activity
CJF59_RS07020	COG4774	siderophore transport
CJF59_RS07035	COG4774	siderophore transport
CJF59_RS07055	COG0848	biopolymer transport protein
CJF59_RS07070	COG1914	H( )-stimulated, divalent metal cation uptake system
CJF59_RS07075	COG1321	iron dependent repressor
CJF59_RS07085	COG4558	Periplasmic binding protein
CJF59_RS07090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJF59_RS07095	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CJF59_RS07120	COG1960	acyl-CoA dehydrogenase activity
CJF59_RS07130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJF59_RS07155	COG3665	Urea carboxylase-associated protein
CJF59_RS07160	COG3665	Urea carboxylase-associated protein
CJF59_RS07165	COG0864	Transcriptional regulator
CJF59_RS07170	COG1116	anion transmembrane transporter activity
CJF59_RS07175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJF59_RS07190	COG0477	Major facilitator Superfamily
CJF59_RS07255	COG4178	(ABC) transporter
CJF59_RS07290	COG3459	Glycosyltransferase 36 associated
CJF59_RS07305	COG0753	catalase activity
CJF59_RS07310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CJF59_RS07330	COG1657	PFAM Prenyltransferase squalene oxidase
CJF59_RS07345	COG0842	Transport permease protein
CJF59_RS07350	COG1129	ABC transporter
CJF59_RS07350	COG0842	Transport permease protein
CJF59_RS07355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF59_RS07395	COG0402	S-adenosylhomocysteine deaminase activity
CJF59_RS07405	COG2072	flavoprotein involved in K transport
CJF59_RS07420	COG2351	hydroxyisourate hydrolase activity
CJF59_RS07425	COG2233	PERMEase
CJF59_RS07435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CJF59_RS07460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CJF59_RS07470	COG4206	TonB-dependent receptor
CJF59_RS07510	COG0384	phenazine biosynthesis protein PhzF
CJF59_RS07520	COG0814	amino acid
CJF59_RS07525	COG2824	Alkylphosphonate utilization operon protein PhnA
CJF59_RS07540	COG0488	(ABC) transporter
CJF59_RS07545	COG0784	Response regulator, receiver
CJF59_RS07570	COG4988	ABC transporter
CJF59_RS07575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CJF59_RS07590	COG1349	DNA-binding transcription factor activity
CJF59_RS07600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJF59_RS07605	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CJF59_RS07615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CJF59_RS07620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJF59_RS07625	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CJF59_RS07630	COG0456	acetyltransferase
CJF59_RS07635	COG1028	Short-chain dehydrogenase reductase Sdr
CJF59_RS07660	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CJF59_RS07675	COG0525	valine-tRNA ligase activity
CJF59_RS07680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJF59_RS07685	COG1116	anion transmembrane transporter activity
CJF59_RS07690	COG1176	ABC-type spermidine putrescine transport system, permease component I
CJF59_RS07695	COG0756	dUTP diphosphatase activity
CJF59_RS07700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CJF59_RS07705	COG2226	methyltransferase
CJF59_RS07710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CJF59_RS07715	COG0268	Binds directly to 16S ribosomal RNA
CJF59_RS07720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJF59_RS07730	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CJF59_RS07740	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CJF59_RS07745	COG0504	CTP synthase activity
CJF59_RS07755	COG0149	triose-phosphate isomerase activity
CJF59_RS07765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJF59_RS07775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJF59_RS07780	COG0134	indole-3-glycerol-phosphate synthase activity
CJF59_RS07785	COG0315	cyclic pyranopterin monophosphate synthase activity
CJF59_RS07790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJF59_RS07795	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJF59_RS07795	COG0022	dehydrogenase e1 component
CJF59_RS07800	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJF59_RS07805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJF59_RS07810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CJF59_RS07825	COG1546	Belongs to the CinA family
CJF59_RS07840	COG0861	Integral membrane protein TerC family
CJF59_RS07845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CJF59_RS07850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CJF59_RS07855	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJF59_RS07865	COG0047	phosphoribosylformylglycinamidine synthase activity
CJF59_RS07870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJF59_RS07875	COG0271	Belongs to the BolA IbaG family
CJF59_RS07880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CJF59_RS07890	COG0792	nuclease activity
CJF59_RS07895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CJF59_RS07910	COG2897	thiosulfate sulfurtransferase activity
CJF59_RS07915	COG0626	cystathionine gamma-synthase activity
CJF59_RS07920	COG0606	chelatase, subunit chli
CJF59_RS07925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJF59_RS07935	COG3474	cytochrome
CJF59_RS07940	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CJF59_RS07945	COG1605	Chorismate mutase
CJF59_RS07945	COG0077	Prephenate dehydratase
CJF59_RS07950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJF59_RS07955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CJF59_RS07960	COG1278	Cold shock
CJF59_RS07990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CJF59_RS08000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJF59_RS08005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJF59_RS08010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJF59_RS08030	COG1663	tetraacyldisaccharide 4'-kinase activity
CJF59_RS08035	COG1519	Transferase
CJF59_RS08045	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJF59_RS08060	COG0175	sulfate reduction
CJF59_RS08065	COG0175	sulfate reduction
CJF59_RS08075	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJF59_RS08080	COG0602	queuosine metabolic process
CJF59_RS08085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CJF59_RS08095	COG0579	oxidoreductase
CJF59_RS08100	COG1764	response to oxidative stress
CJF59_RS08105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CJF59_RS08110	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CJF59_RS08115	COG0259	pyridoxamine-phosphate oxidase activity
CJF59_RS08130	COG0084	hydrolase, TatD family'
CJF59_RS08145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CJF59_RS08150	COG1686	Belongs to the peptidase S11 family
CJF59_RS08155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CJF59_RS08160	COG2951	lytic endotransglycosylase activity
CJF59_RS08175	COG0531	amino acid
CJF59_RS08180	COG1968	undecaprenyl-diphosphatase activity
CJF59_RS08205	COG2890	protein-(glutamine-N5) methyltransferase activity
CJF59_RS08215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CJF59_RS08220	COG0124	histidyl-tRNA synthetase
CJF59_RS08225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CJF59_RS08235	COG2070	2-Nitropropane dioxygenase
CJF59_RS08240	COG0527	aspartate kinase activity
CJF59_RS08245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJF59_RS08250	COG2706	6-phosphogluconolactonase activity
CJF59_RS08275	COG2226	methyltransferase
CJF59_RS08280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CJF59_RS08300	COG0321	lipoyl(octanoyl) transferase activity
CJF59_RS08310	COG0271	Belongs to the BolA IbaG family
CJF59_RS08315	COG0484	heat shock protein binding
CJF59_RS08330	COG0076	glutamate decarboxylase activity
CJF59_RS08345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CJF59_RS08350	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CJF59_RS08365	COG2022	thiamine diphosphate biosynthetic process
CJF59_RS08385	COG0148	phosphopyruvate hydratase activity
CJF59_RS08395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJF59_RS08400	COG0303	'Molybdopterin
CJF59_RS08405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CJF59_RS08410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CJF59_RS08410	COG4106	trans-aconitate 2-methyltransferase activity
CJF59_RS08420	COG0156	8-amino-7-oxononanoate synthase activity
CJF59_RS08425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJF59_RS08430	COG0314	molybdopterin synthase activity
CJF59_RS08435	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CJF59_RS08450	COG0322	excinuclease ABC activity
CJF59_RS08470	COG0729	surface antigen
CJF59_RS08480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJF59_RS08490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CJF59_RS08500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CJF59_RS08530	COG0287	Prephenate dehydrogenase
CJF59_RS08530	COG1605	Chorismate mutase
CJF59_RS08535	COG2062	phosphohistidine phosphatase, SixA
CJF59_RS08550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CJF59_RS08555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CJF59_RS08560	COG0142	geranyltranstransferase activity
CJF59_RS08570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJF59_RS08575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CJF59_RS08575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJF59_RS08585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJF59_RS08590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJF59_RS08600	COG1970	mechanosensitive ion channel activity
CJF59_RS08605	COG0254	rRNA binding
CJF59_RS08610	COG0071	Belongs to the small heat shock protein (HSP20) family
CJF59_RS08635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJF59_RS08640	COG2003	Belongs to the UPF0758 family
CJF59_RS08645	COG2003	Belongs to the UPF0758 family
CJF59_RS08655	COG2264	protein methyltransferase activity
CJF59_RS08660	COG0006	proline dipeptidase activity
CJF59_RS08665	COG0473	3-isopropylmalate dehydrogenase activity
CJF59_RS08680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CJF59_RS08705	COG0747	negative chemotaxis
CJF59_RS08710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CJF59_RS08715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJF59_RS08715	COG0072	phenylalanine-tRNA ligase activity
CJF59_RS08720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CJF59_RS08725	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CJF59_RS08730	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CJF59_RS08735	COG0246	Mannitol dehydrogenase
CJF59_RS08740	COG2010	Cytochrome c
CJF59_RS08740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CJF59_RS08755	COG2166	iron-sulfur cluster assembly
CJF59_RS08760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CJF59_RS08765	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CJF59_RS08790	COG2884	Cell division ATP-binding protein ftsE
CJF59_RS08805	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CJF59_RS08810	COG3781	membrane
CJF59_RS08820	COG0859	PFAM glycosyl transferase family 9
CJF59_RS08820	COG0457	Tetratricopeptide repeat
CJF59_RS08830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CJF59_RS08835	COG2081	HI0933 family
CJF59_RS08845	COG0850	regulation of cytokinetic process
CJF59_RS08855	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CJF59_RS08860	COG1802	Transcriptional regulator
CJF59_RS08865	COG1132	(ABC) transporter
CJF59_RS08895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CJF59_RS08900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJF59_RS08905	COG0359	binds to the 23S rRNA
CJF59_RS08910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CJF59_RS08915	COG0360	Binds together with S18 to 16S ribosomal RNA
CJF59_RS08925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJF59_RS08930	COG0358	DNA primase activity
CJF59_RS08940	COG0505	Belongs to the CarA family
CJF59_RS08945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CJF59_RS08950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJF59_RS08955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJF59_RS08960	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CJF59_RS08975	COG0793	Belongs to the peptidase S41A family
CJF59_RS08985	COG1051	belongs to the nudix hydrolase family
CJF59_RS08990	COG2814	Major facilitator Superfamily
CJF59_RS09000	COG1132	(ABC) transporter
CJF59_RS09005	COG0617	tRNA 3'-terminal CCA addition
CJF59_RS09015	COG0714	Associated with various cellular activities
CJF59_RS09040	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CJF59_RS09045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJF59_RS09050	COG3237	CsbD-like
CJF59_RS09060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF59_RS09080	COG5487	UPF0391 membrane protein
CJF59_RS09090	COG1116	anion transmembrane transporter activity
CJF59_RS09095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJF59_RS09105	COG0203	ribosomal protein L17
CJF59_RS09110	COG0202	RNA polymerase activity
CJF59_RS09115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CJF59_RS09120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CJF59_RS09125	COG0563	adenylate kinase activity
CJF59_RS09135	COG0200	Binds to the 23S rRNA
CJF59_RS09140	COG1841	ribosomal large subunit assembly
CJF59_RS09145	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CJF59_RS09150	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CJF59_RS09155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CJF59_RS09160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CJF59_RS09165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJF59_RS09170	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CJF59_RS09175	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CJF59_RS09180	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CJF59_RS09185	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CJF59_RS09190	COG0255	Belongs to the universal ribosomal protein uL29 family
CJF59_RS09195	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CJF59_RS09200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CJF59_RS09205	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CJF59_RS09210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CJF59_RS09215	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CJF59_RS09220	COG0089	rRNA binding
CJF59_RS09225	COG0088	Forms part of the polypeptide exit tunnel
CJF59_RS09230	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CJF59_RS09235	COG0051	transcription antitermination factor activity, RNA binding
CJF59_RS09240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJF59_RS09245	COG0049	tRNA binding
CJF59_RS09250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CJF59_RS09255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CJF59_RS09260	COG0085	RNA polymerase activity
CJF59_RS09270	COG0222	ribosome binding
CJF59_RS09275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CJF59_RS09280	COG0081	regulation of translation
CJF59_RS09285	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CJF59_RS09315	COG1322	Protein conserved in bacteria
CJF59_RS09320	COG0477	Major facilitator Superfamily
CJF59_RS09330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CJF59_RS09360	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CJF59_RS09395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJF59_RS09400	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CJF59_RS09405	COG1138	Cytochrome C-type biogenesis protein
CJF59_RS09410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJF59_RS09415	COG3088	subunit of a heme lyase
CJF59_RS09435	COG1289	transmembrane transporter activity
CJF59_RS09440	COG1289	transmembrane transporter activity
CJF59_RS09465	COG1121	(ABC) transporter
CJF59_RS09480	COG0248	Ppx GppA phosphatase
CJF59_RS09485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CJF59_RS09495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CJF59_RS09500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CJF59_RS09510	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJF59_RS09530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CJF59_RS09535	COG0237	dephospho-CoA kinase activity
CJF59_RS09540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJF59_RS09560	COG0165	Argininosuccinate lyase
CJF59_RS09565	COG0019	diaminopimelate decarboxylase activity
CJF59_RS09575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJF59_RS09580	COG3591	Belongs to the peptidase S1B family
CJF59_RS09590	COG0640	Transcriptional regulator
CJF59_RS09595	COG1902	pentaerythritol trinitrate reductase activity
CJF59_RS09600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CJF59_RS09690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJF59_RS09715	COG1201	RNA secondary structure unwinding
CJF59_RS09795	COG3551	Protein conserved in bacteria
CJF59_RS09825	COG0778	Nitroreductase
CJF59_RS09845	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CJF59_RS09850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJF59_RS09850	COG2857	Cytochrome c1
CJF59_RS09855	COG2857	Cytochrome c1
CJF59_RS09855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJF59_RS09860	COG0408	coproporphyrinogen oxidase activity
CJF59_RS09880	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CJF59_RS09890	COG0406	alpha-ribazole phosphatase activity
CJF59_RS09895	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CJF59_RS09905	COG0181	hydroxymethylbilane synthase activity
CJF59_RS09910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CJF59_RS09915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CJF59_RS09935	COG1058	Belongs to the CinA family
CJF59_RS09935	COG1546	Belongs to the CinA family
CJF59_RS09940	COG0825	malonyl-CoA metabolic process
CJF59_RS09945	COG4974	Belongs to the 'phage' integrase family
CJF59_RS09955	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CJF59_RS09960	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CJF59_RS09960	COG2885	chlorophyll binding
CJF59_RS09970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJF59_RS09975	COG0688	phosphatidylethanolamine metabolic process
CJF59_RS09980	COG1183	phosphatidylcholine synthase activity
CJF59_RS09985	COG3260	NADH ubiquinone oxidoreductase 20
CJF59_RS10020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF59_RS10035	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CJF59_RS10055	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJF59_RS10065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CJF59_RS10070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJF59_RS10075	COG2333	competence protein COMEC
CJF59_RS10075	COG0658	competence protein
CJF59_RS10080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJF59_RS10085	COG0540	Belongs to the ATCase OTCase family
CJF59_RS10090	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJF59_RS10095	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CJF59_RS10100	COG0758	DNA mediated transformation
CJF59_RS10105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJF59_RS10110	COG0557	exoribonuclease II activity
CJF59_RS10115	COG0793	Belongs to the peptidase S41A family
CJF59_RS10125	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CJF59_RS10125	COG2885	chlorophyll binding
CJF59_RS10130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJF59_RS10135	COG1959	2 iron, 2 sulfur cluster binding
CJF59_RS10150	COG0187	DNA topoisomerase II activity
CJF59_RS10155	COG5006	permease, DMT superfamily
CJF59_RS10165	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CJF59_RS10175	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CJF59_RS10180	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CJF59_RS10185	COG0196	riboflavin kinase activity
CJF59_RS10190	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CJF59_RS10195	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CJF59_RS10200	COG0235	Class ii aldolase
CJF59_RS10205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJF59_RS10220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJF59_RS10225	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CJF59_RS10245	COG1643	Atp-dependent helicase
CJF59_RS10255	COG0656	L-ascorbic acid biosynthetic process
CJF59_RS10265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJF59_RS10275	COG0009	L-threonylcarbamoyladenylate synthase
CJF59_RS10285	COG0277	FAD linked oxidase domain protein
CJF59_RS10300	COG2096	Adenosyltransferase
CJF59_RS10330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJF59_RS10345	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CJF59_RS10345	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CJF59_RS10345	COG0506	proline dehydrogenase activity
CJF59_RS10355	COG1113	amino acid transport
CJF59_RS10385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJF59_RS10390	COG1127	ABC transporter
CJF59_RS10395	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CJF59_RS10395	COG3264	Mechanosensitive ion channel
CJF59_RS10400	COG0305	Participates in initiation and elongation during chromosome replication
CJF59_RS10405	COG2942	2-epimerase
CJF59_RS10410	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CJF59_RS10410	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CJF59_RS10415	COG0194	GDP metabolic process
CJF59_RS10430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJF59_RS10440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CJF59_RS10440	COG0517	IMP dehydrogenase activity
CJF59_RS10455	COG1137	ATPase activity
CJF59_RS10460	COG0633	Ferredoxin
CJF59_RS10460	COG3217	Mosc domain protein beta barrel domain protein
CJF59_RS10470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CJF59_RS10490	COG0242	peptide deformylase activity
CJF59_RS10495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJF59_RS10500	COG0101	tRNA pseudouridine synthase activity
CJF59_RS10510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJF59_RS10515	COG2171	N-acyltransferase activity
CJF59_RS10520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJF59_RS10525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CJF59_RS10530	COG0706	membrane insertase activity
CJF59_RS10535	COG0594	ribonuclease P activity
CJF59_RS10540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CJF59_RS10550	COG0346	lactoylglutathione lyase activity
CJF59_RS10555	COG3494	Protein of unknown function (DUF1009)
CJF59_RS10560	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF59_RS10565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJF59_RS10570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF59_RS10585	COG0750	zinc metalloprotease
CJF59_RS10590	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CJF59_RS10600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CJF59_RS10605	COG0233	cytoplasmic translational termination
CJF59_RS10610	COG0528	UMP kinase activity
CJF59_RS10620	COG0571	ribonuclease III activity
CJF59_RS10625	COG0681	Belongs to the peptidase S26 family
CJF59_RS10630	COG0736	holo-[acyl-carrier-protein] synthase activity
CJF59_RS10635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJF59_RS10640	COG1758	RNA polymerase activity
CJF59_RS10665	COG0513	Belongs to the DEAD box helicase family
CJF59_RS10670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJF59_RS10670	COG2813	Specifically methylates the guanine in position
CJF59_RS10675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJF59_RS10680	COG0481	GTPase activity
CJF59_RS10695	COG4993	Dehydrogenase
CJF59_RS10735	COG0538	isocitrate dehydrogenase activity
CJF59_RS10740	COG0492	ferredoxin-NADP+ reductase activity
CJF59_RS10745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJF59_RS10755	COG1217	gtp-binding protein TYPA
CJF59_RS10775	COG0469	pyruvate kinase activity
CJF59_RS10785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CJF59_RS10820	COG1297	OPT oligopeptide transporter protein
CJF59_RS10835	COG0596	Alpha beta hydrolase
CJF59_RS10840	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CJF59_RS10850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CJF59_RS10860	COG0523	cobalamin synthesis protein
CJF59_RS10870	COG1252	NADH dehydrogenase
CJF59_RS10880	COG0071	Belongs to the small heat shock protein (HSP20) family
CJF59_RS10890	COG0022	dehydrogenase e1 component
CJF59_RS10895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJF59_RS10905	COG0306	phosphate transporter
CJF59_RS10950	COG1607	acyl-coa hydrolase
CJF59_RS10970	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJF59_RS10975	COG4221	oxidoreductase activity
CJF59_RS10980	COG1959	2 iron, 2 sulfur cluster binding
CJF59_RS11135	COG1054	Belongs to the UPF0176 family
CJF59_RS11250	COG4774	siderophore transport
CJF59_RS11465	COG1802	Transcriptional regulator
CJF59_RS11465	COG4626	Terminase
CJF59_RS11580	COG1611	Belongs to the LOG family
CJF59_RS11595	COG1981	membrane
CJF59_RS11600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJF59_RS11605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CJF59_RS11610	COG0424	maF-like protein
CJF59_RS11625	COG1671	Belongs to the UPF0178 family
CJF59_RS11635	COG2814	Major facilitator Superfamily
CJF59_RS11645	COG2835	tetraacyldisaccharide 4'-kinase activity
CJF59_RS11650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CJF59_RS11660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJF59_RS11685	COG0778	Nitroreductase
CJF59_RS11695	COG0456	acetyltransferase
CJF59_RS11705	COG1570	exodeoxyribonuclease VII activity
CJF59_RS11720	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJF59_RS11725	COG1012	belongs to the aldehyde dehydrogenase family
CJF59_RS11735	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CJF59_RS11750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CJF59_RS11760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CJF59_RS11765	COG1053	succinate dehydrogenase
CJF59_RS11770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJF59_RS11785	COG0126	phosphoglycerate kinase activity
CJF59_RS11795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CJF59_RS11805	COG0156	8-amino-7-oxononanoate synthase activity
CJF59_RS11815	COG0405	Gamma-glutamyltransferase
CJF59_RS11835	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CJF59_RS11845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CJF59_RS11870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CJF59_RS11875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CJF59_RS11885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CJF59_RS11895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CJF59_RS11900	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CJF59_RS11905	COG0539	negative regulation of cytoplasmic translation
CJF59_RS11920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CJF59_RS11925	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CJF59_RS11930	COG1420	regulation of RNA biosynthetic process
CJF59_RS11935	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CJF59_RS11970	COG0772	Belongs to the SEDS family
CJF59_RS11975	COG0768	penicillin binding
CJF59_RS11995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJF59_RS12000	COG1612	heme a metabolic process
CJF59_RS12010	COG2814	Major facilitator Superfamily
CJF59_RS12020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJF59_RS12025	COG1289	transmembrane transporter activity
CJF59_RS12035	COG1573	uracil-dna glycosylase
CJF59_RS12055	COG0670	Belongs to the BI1 family
CJF59_RS12080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CJF59_RS12095	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJF59_RS12110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJF59_RS12130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJF59_RS12155	COG1028	Short-chain dehydrogenase reductase Sdr
CJF59_RS12160	COG0586	Pfam SNARE associated Golgi protein
CJF59_RS12170	COG0281	malic enzyme
CJF59_RS12200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJF59_RS12205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CJF59_RS12210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CJF59_RS12215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CJF59_RS12220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJF59_RS12225	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CJF59_RS12230	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CJF59_RS12235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJF59_RS12250	COG1113	amino acid transport
CJF59_RS12255	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CJF59_RS12260	COG4208	sulfate ABC transporter
CJF59_RS12280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CJF59_RS12285	COG2207	Transcriptional regulator
CJF59_RS12290	COG4303	Ethanolamine ammonia lyase large subunit
CJF59_RS12295	COG4302	ethanolamine ammonia-lyase activity
CJF59_RS12300	COG1113	amino acid transport
CJF59_RS12310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF59_RS12325	COG1278	Cold shock
CJF59_RS12365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJF59_RS12375	COG0784	Response regulator, receiver
CJF59_RS12375	COG2205	protein histidine kinase activity
CJF59_RS12400	COG3842	ATPase activity
CJF59_RS12540	COG3177	Filamentation induced by cAMP protein fic
CJF59_RS12585	COG2983	Belongs to the UPF0260 family
CJF59_RS12625	COG1566	PFAM secretion protein HlyD family protein
CJF59_RS12645	COG1657	PFAM Prenyltransferase squalene oxidase
CJF59_RS12650	COG1233	COG1233 Phytoene dehydrogenase and related
CJF59_RS12655	COG1562	ergosterol biosynthetic process
CJF59_RS12660	COG1562	ergosterol biosynthetic process
CJF59_RS12665	COG1215	transferase activity, transferring glycosyl groups
CJF59_RS12670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF59_RS12680	COG0287	Prephenate dehydrogenase
CJF59_RS12690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJF59_RS12700	COG0450	alkyl hydroperoxide reductase
CJF59_RS12705	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJF59_RS12715	COG2353	YceI-like domain
CJF59_RS12725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CJF59_RS12735	COG0488	(ABC) transporter
CJF59_RS12755	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CJF59_RS12765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJF59_RS12770	COG0343	queuine tRNA-ribosyltransferase activity
CJF59_RS12775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CJF59_RS12785	COG1881	PFAM PEBP family protein
CJF59_RS12800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CJF59_RS12815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJF59_RS12845	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CJF59_RS12850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CJF59_RS12865	COG0667	Aldo Keto reductase
CJF59_RS12875	COG0556	nucleotide-excision repair
CJF59_RS12885	COG0612	Peptidase, M16
CJF59_RS12905	COG0463	Glycosyl transferase, family 2
CJF59_RS12920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJF59_RS12930	COG0167	dihydroorotate dehydrogenase activity
CJF59_RS12945	COG1692	metallophosphoesterase
CJF59_RS12950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CJF59_RS12980	COG0352	thiamine-phosphate diphosphorylase activity
CJF59_RS13005	COG1509	lysine 2,3-aminomutase activity
CJF59_RS13015	COG0024	Methionine aminopeptidase
CJF59_RS13020	COG1686	Belongs to the peptidase S11 family
CJF59_RS13025	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CJF59_RS13040	COG2326	polyphosphate kinase activity
CJF59_RS13045	COG1678	Uncharacterized ACR, COG1678
CJF59_RS13050	COG1660	Displays ATPase and GTPase activities
CJF59_RS13060	COG2205	protein histidine kinase activity
CJF59_RS13065	COG0745	RESPONSE REGULATOR receiver
CJF59_RS13070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CJF59_RS13075	COG0443	Heat shock 70 kDa protein
CJF59_RS13080	COG0484	heat shock protein binding
CJF59_RS13085	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJF59_RS13090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CJF59_RS13095	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJF59_RS13100	COG0138	bifunctional purine biosynthesis protein purh
CJF59_RS13115	COG0697	spore germination
CJF59_RS13125	COG0752	glycyl-tRNA synthetase alpha subunit
CJF59_RS13135	COG1396	sequence-specific DNA binding
CJF59_RS13140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CJF59_RS13160	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CJF59_RS13170	COG0598	Magnesium transport protein CorA
CJF59_RS13175	COG0133	tryptophan synthase activity
CJF59_RS13180	COG0159	tryptophan synthase activity
CJF59_RS13185	COG0493	'glutamate synthase
CJF59_RS13195	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CJF59_RS13200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJF59_RS13205	COG0745	RESPONSE REGULATOR receiver
CJF59_RS13215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CJF59_RS13240	COG1253	flavin adenine dinucleotide binding
CJF59_RS13245	COG0604	alcohol dehydrogenase
CJF59_RS13255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF59_RS13270	COG1028	Short-chain dehydrogenase reductase Sdr
CJF59_RS13275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CJF59_RS13280	COG3956	TIGRFAM MazG family protein
CJF59_RS13290	COG0326	Molecular chaperone. Has ATPase activity
CJF59_RS13395	COG1396	sequence-specific DNA binding
CJF59_RS13420	COG0629	single-stranded DNA binding
CJF59_RS13715	COG2755	lipolytic protein G-D-S-L family
CJF59_RS13715	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CJF59_RS13740	COG1396	sequence-specific DNA binding
CJF59_RS13740	COG3800	Transcriptional regulator
CJF59_RS13745	COG2079	MmgE PrpD family protein
CJF59_RS13750	COG0372	Belongs to the citrate synthase family
CJF59_RS13755	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CJF59_RS13760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJF59_RS13765	COG2814	Major facilitator Superfamily
CJF59_RS13770	COG2319	Wd-40 repeat
CJF59_RS13780	COG2309	aminopeptidase activity
CJF59_RS13795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CJF59_RS13805	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CJF59_RS13810	COG0193	aminoacyl-tRNA hydrolase activity
CJF59_RS13815	COG0012	GTP binding
CJF59_RS13820	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CJF59_RS13825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CJF59_RS13830	COG0799	negative regulation of ribosome biogenesis
CJF59_RS13835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CJF59_RS13870	COG0247	lactate metabolic process
CJF59_RS13875	COG1139	Iron-sulfur cluster binding protein
CJF59_RS13885	COG0697	spore germination
CJF59_RS13890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJF59_RS13895	COG0717	Belongs to the dCTP deaminase family
CJF59_RS13910	COG3394	polysaccharide catabolic process
CJF59_RS13945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CJF59_RS13950	COG1253	flavin adenine dinucleotide binding
CJF59_RS13955	COG0741	lytic transglycosylase activity
CJF59_RS13960	COG1573	uracil-dna glycosylase
CJF59_RS13970	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CJF59_RS13980	COG4221	oxidoreductase activity
CJF59_RS14010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CJF59_RS14050	COG1028	Short-chain dehydrogenase reductase Sdr
CJF59_RS14060	COG0025	NhaP-type Na H and K H
CJF59_RS14065	COG4771	TonB-dependent receptor
CJF59_RS14075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJF59_RS14080	COG1120	ATPase activity
CJF59_RS14085	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CJF59_RS14090	COG2971	BadF BadG BcrA BcrD
CJF59_RS14095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CJF59_RS14115	COG0415	Belongs to the DNA photolyase family
CJF59_RS14120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJF59_RS14150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CJF59_RS14235	COG1012	belongs to the aldehyde dehydrogenase family
CJF59_RS14425	COG2963	transposase activity
CJF59_RS14440	COG0438	transferase activity, transferring glycosyl groups
CJF59_RS14455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CJF59_RS14475	COG4372	Transposase
CJF59_RS14485	COG2963	transposase activity
CJF59_RS14610	COG0735	belongs to the Fur family
CJF59_RS14620	COG0302	gtp cyclohydrolase
CJF59_RS14625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJF59_RS14630	COG0523	cobalamin synthesis protein
CJF59_RS14645	COG0640	Transcriptional regulator
CJF59_RS14675	COG0679	Auxin Efflux Carrier
CJF59_RS14685	COG3293	Transposase
CJF59_RS14720	COG0028	Belongs to the TPP enzyme family
CJF59_RS14785	COG1959	2 iron, 2 sulfur cluster binding
CJF59_RS14800	COG4221	oxidoreductase activity
CJF59_RS14845	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CJF59_RS14850	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CJF59_RS14860	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CJF59_RS14910	COG1475	DNA binding
CJF59_RS14945	COG4227	nucleotidyltransferase activity
CJF59_RS14960	COG0629	single-stranded DNA binding
CJF59_RS14975	COG0210	DNA helicase
CJF59_RS15010	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CJF59_RS15025	COG0732	type I restriction modification DNA specificity domain
CJF59_RS15030	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CJF59_RS15040	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CJF59_RS15065	COG3093	addiction module antidote protein HigA
CJF59_RS15265	COG1216	Glycosyl transferase, family 2
CJF59_RS15270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CJF59_RS15295	COG2026	Addiction module toxin, RelE StbE family
CJF59_RS15315	COG0640	Transcriptional regulator
CJF59_RS15325	COG3750	Belongs to the UPF0335 family
CJF59_RS15330	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CJF59_RS15385	COG1476	TRANSCRIPTIONal
CJF59_RS15405	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CJF59_RS15415	COG2336	PFAM SpoVT AbrB
CJF59_RS15420	COG2337	Toxic component of a toxin-antitoxin (TA) module