locus-tag	class	description
DS739_RS00055	COG1611	Belongs to the LOG family
DS739_RS00070	COG1981	membrane
DS739_RS00080	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DS739_RS00085	COG0424	maF-like protein
DS739_RS00100	COG1671	Belongs to the UPF0178 family
DS739_RS00110	COG2814	Major facilitator Superfamily
DS739_RS00120	COG2835	tetraacyldisaccharide 4'-kinase activity
DS739_RS00125	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DS739_RS00135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DS739_RS00160	COG0778	Nitroreductase
DS739_RS00170	COG0456	acetyltransferase
DS739_RS00180	COG1570	exodeoxyribonuclease VII activity
DS739_RS00195	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DS739_RS00200	COG1012	belongs to the aldehyde dehydrogenase family
DS739_RS00210	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DS739_RS00225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DS739_RS00235	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DS739_RS00240	COG1053	succinate dehydrogenase
DS739_RS00245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DS739_RS00260	COG0126	phosphoglycerate kinase activity
DS739_RS00270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DS739_RS00280	COG0156	8-amino-7-oxononanoate synthase activity
DS739_RS00285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DS739_RS00290	COG0405	Gamma-glutamyltransferase
DS739_RS00310	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DS739_RS00320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DS739_RS00345	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DS739_RS00350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DS739_RS00360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DS739_RS00370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DS739_RS00375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DS739_RS00380	COG0539	negative regulation of cytoplasmic translation
DS739_RS00395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DS739_RS00400	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DS739_RS00405	COG1420	regulation of RNA biosynthetic process
DS739_RS00445	COG0772	Belongs to the SEDS family
DS739_RS00450	COG0768	penicillin binding
DS739_RS00470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DS739_RS00475	COG1612	heme a metabolic process
DS739_RS00485	COG2814	Major facilitator Superfamily
DS739_RS00495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DS739_RS00500	COG1289	transmembrane transporter activity
DS739_RS00510	COG1573	uracil-dna glycosylase
DS739_RS00530	COG0670	Belongs to the BI1 family
DS739_RS00555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DS739_RS00570	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DS739_RS00585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DS739_RS00605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DS739_RS00630	COG1028	Short-chain dehydrogenase reductase Sdr
DS739_RS00635	COG0586	Pfam SNARE associated Golgi protein
DS739_RS00645	COG0281	malic enzyme
DS739_RS00675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DS739_RS00680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DS739_RS00685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DS739_RS00690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DS739_RS00695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DS739_RS00700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DS739_RS00705	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DS739_RS00710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DS739_RS00725	COG1113	amino acid transport
DS739_RS00730	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DS739_RS00735	COG4208	sulfate ABC transporter
DS739_RS00755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DS739_RS00760	COG2207	Transcriptional regulator
DS739_RS00765	COG4303	Ethanolamine ammonia lyase large subunit
DS739_RS00770	COG4302	ethanolamine ammonia-lyase activity
DS739_RS00775	COG1113	amino acid transport
DS739_RS00780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DS739_RS00795	COG1278	Cold shock
DS739_RS00835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DS739_RS00840	COG0745	RESPONSE REGULATOR receiver
DS739_RS00845	COG0745	RESPONSE REGULATOR receiver
DS739_RS00880	COG3842	ATPase activity
DS739_RS00925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DS739_RS00985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DS739_RS01055	COG2983	Belongs to the UPF0260 family
DS739_RS01095	COG1566	PFAM secretion protein HlyD family protein
DS739_RS01115	COG1657	PFAM Prenyltransferase squalene oxidase
DS739_RS01120	COG1233	COG1233 Phytoene dehydrogenase and related
DS739_RS01125	COG1562	ergosterol biosynthetic process
DS739_RS01130	COG1562	ergosterol biosynthetic process
DS739_RS01135	COG1215	transferase activity, transferring glycosyl groups
DS739_RS01140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DS739_RS01150	COG0287	Prephenate dehydrogenase
DS739_RS01160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DS739_RS01170	COG0450	alkyl hydroperoxide reductase
DS739_RS01175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DS739_RS01185	COG2353	YceI-like domain
DS739_RS01195	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DS739_RS01205	COG0488	(ABC) transporter
DS739_RS01225	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DS739_RS01235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DS739_RS01240	COG0343	queuine tRNA-ribosyltransferase activity
DS739_RS01245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DS739_RS01255	COG1881	PFAM PEBP family protein
DS739_RS01270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DS739_RS01285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS739_RS01315	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DS739_RS01335	COG0667	Aldo Keto reductase
DS739_RS01345	COG0556	nucleotide-excision repair
DS739_RS01355	COG0612	Peptidase, M16
DS739_RS01375	COG0463	Glycosyl transferase, family 2
DS739_RS01390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DS739_RS01400	COG0167	dihydroorotate dehydrogenase activity
DS739_RS01415	COG1692	metallophosphoesterase
DS739_RS01420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DS739_RS01450	COG0352	thiamine-phosphate diphosphorylase activity
DS739_RS01475	COG1509	lysine 2,3-aminomutase activity
DS739_RS01485	COG0024	Methionine aminopeptidase
DS739_RS01490	COG1686	Belongs to the peptidase S11 family
DS739_RS01495	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DS739_RS01510	COG2326	polyphosphate kinase activity
DS739_RS01515	COG1678	Uncharacterized ACR, COG1678
DS739_RS01520	COG1660	Displays ATPase and GTPase activities
DS739_RS01530	COG2205	protein histidine kinase activity
DS739_RS01535	COG0745	RESPONSE REGULATOR receiver
DS739_RS01540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DS739_RS01545	COG0443	Heat shock 70 kDa protein
DS739_RS01550	COG0484	heat shock protein binding
DS739_RS01555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DS739_RS01565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DS739_RS01570	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DS739_RS01575	COG0138	bifunctional purine biosynthesis protein purh
DS739_RS01590	COG0697	spore germination
DS739_RS01600	COG0752	glycyl-tRNA synthetase alpha subunit
DS739_RS01610	COG1396	sequence-specific DNA binding
DS739_RS01615	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DS739_RS01635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DS739_RS01645	COG0598	Magnesium transport protein CorA
DS739_RS01650	COG0133	tryptophan synthase activity
DS739_RS01655	COG0159	tryptophan synthase activity
DS739_RS01660	COG0493	'glutamate synthase
DS739_RS01670	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DS739_RS01675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DS739_RS01680	COG0745	RESPONSE REGULATOR receiver
DS739_RS01690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DS739_RS01715	COG1253	flavin adenine dinucleotide binding
DS739_RS01720	COG0604	alcohol dehydrogenase
DS739_RS01730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DS739_RS01745	COG1028	Short-chain dehydrogenase reductase Sdr
DS739_RS01750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DS739_RS01755	COG3956	TIGRFAM MazG family protein
DS739_RS01765	COG0326	Molecular chaperone. Has ATPase activity
DS739_RS01795	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DS739_RS01825	COG0318	PFAM AMP-dependent synthetase and ligase
DS739_RS01840	COG1028	Short-chain dehydrogenase reductase Sdr
DS739_RS01840	COG3321	synthase
DS739_RS01840	COG0604	alcohol dehydrogenase
DS739_RS01845	COG0318	PFAM AMP-dependent synthetase and ligase
DS739_RS01855	COG2223	nitrite transmembrane transporter activity
DS739_RS01915	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DS739_RS01915	COG2755	lipolytic protein G-D-S-L family
DS739_RS01940	COG1396	sequence-specific DNA binding
DS739_RS01940	COG3800	Transcriptional regulator
DS739_RS01945	COG2079	MmgE PrpD family protein
DS739_RS01950	COG0372	Belongs to the citrate synthase family
DS739_RS01955	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DS739_RS01960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DS739_RS01965	COG2814	Major facilitator Superfamily
DS739_RS01970	COG2319	Wd-40 repeat
DS739_RS01980	COG2309	aminopeptidase activity
DS739_RS01995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DS739_RS02005	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DS739_RS02010	COG0193	aminoacyl-tRNA hydrolase activity
DS739_RS02015	COG0012	GTP binding
DS739_RS02020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DS739_RS02025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DS739_RS02030	COG0799	negative regulation of ribosome biogenesis
DS739_RS02035	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DS739_RS02070	COG0247	lactate metabolic process
DS739_RS02075	COG1139	Iron-sulfur cluster binding protein
DS739_RS02090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DS739_RS02095	COG0717	Belongs to the dCTP deaminase family
DS739_RS02110	COG3394	polysaccharide catabolic process
DS739_RS02130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DS739_RS02145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DS739_RS02150	COG1253	flavin adenine dinucleotide binding
DS739_RS02155	COG0741	lytic transglycosylase activity
DS739_RS02160	COG1573	uracil-dna glycosylase
DS739_RS02170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DS739_RS02210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DS739_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
DS739_RS02255	COG0583	DNA-binding transcription factor activity
DS739_RS02260	COG0025	NhaP-type Na H and K H
DS739_RS02265	COG4771	TonB-dependent receptor
DS739_RS02275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS739_RS02280	COG1120	ATPase activity
DS739_RS02285	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DS739_RS02290	COG2971	BadF BadG BcrA BcrD
DS739_RS02295	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DS739_RS02315	COG0415	Belongs to the DNA photolyase family
DS739_RS02320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DS739_RS02360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DS739_RS02405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS739_RS02445	COG1012	belongs to the aldehyde dehydrogenase family
DS739_RS02580	COG4774	siderophore transport
DS739_RS02695	COG1054	Belongs to the UPF0176 family
DS739_RS02850	COG1959	2 iron, 2 sulfur cluster binding
DS739_RS02855	COG4221	oxidoreductase activity
DS739_RS02860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DS739_RS02880	COG1607	acyl-coa hydrolase
DS739_RS02925	COG0306	phosphate transporter
DS739_RS02935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DS739_RS02940	COG0022	dehydrogenase e1 component
DS739_RS02950	COG0071	Belongs to the small heat shock protein (HSP20) family
DS739_RS02960	COG1252	NADH dehydrogenase
DS739_RS02970	COG0523	cobalamin synthesis protein
DS739_RS02980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DS739_RS02990	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DS739_RS02995	COG0596	Alpha beta hydrolase
DS739_RS03010	COG1297	OPT oligopeptide transporter protein
DS739_RS03045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DS739_RS03055	COG0469	pyruvate kinase activity
DS739_RS03075	COG1217	gtp-binding protein TYPA
DS739_RS03085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DS739_RS03090	COG0492	ferredoxin-NADP+ reductase activity
DS739_RS03095	COG0538	isocitrate dehydrogenase activity
DS739_RS03140	COG4993	Dehydrogenase
DS739_RS03155	COG0481	GTPase activity
DS739_RS03160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DS739_RS03165	COG2813	Specifically methylates the guanine in position
DS739_RS03165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DS739_RS03180	COG0582	viral genome integration into host DNA
DS739_RS03305	COG4626	Terminase
DS739_RS03305	COG1802	Transcriptional regulator
DS739_RS03435	COG1758	RNA polymerase activity
DS739_RS03440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DS739_RS03450	COG0681	Belongs to the peptidase S26 family
DS739_RS03455	COG0571	ribonuclease III activity
DS739_RS03465	COG0528	UMP kinase activity
DS739_RS03470	COG0233	cytoplasmic translational termination
DS739_RS03475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DS739_RS03485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DS739_RS03490	COG0750	zinc metalloprotease
DS739_RS03505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DS739_RS03510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DS739_RS03515	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DS739_RS03520	COG3494	Protein of unknown function (DUF1009)
DS739_RS03525	COG0346	lactoylglutathione lyase activity
DS739_RS03535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DS739_RS03540	COG0594	ribonuclease P activity
DS739_RS03545	COG0706	membrane insertase activity
DS739_RS03550	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DS739_RS03555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DS739_RS03560	COG2171	N-acyltransferase activity
DS739_RS03565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DS739_RS03575	COG0101	tRNA pseudouridine synthase activity
DS739_RS03580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DS739_RS03585	COG0242	peptide deformylase activity
DS739_RS03605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DS739_RS03615	COG0633	Ferredoxin
DS739_RS03615	COG3217	Mosc domain protein beta barrel domain protein
DS739_RS03620	COG1137	ATPase activity
DS739_RS03635	COG0517	IMP dehydrogenase activity
DS739_RS03635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DS739_RS03645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DS739_RS03650	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DS739_RS03660	COG0194	GDP metabolic process
DS739_RS03665	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DS739_RS03665	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DS739_RS03670	COG2942	2-epimerase
DS739_RS03675	COG0305	Participates in initiation and elongation during chromosome replication
DS739_RS03680	COG3264	Mechanosensitive ion channel
DS739_RS03680	COG1196	nuclear chromosome segregation
DS739_RS03685	COG1127	ABC transporter
DS739_RS03690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DS739_RS03720	COG1113	amino acid transport
DS739_RS03730	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DS739_RS03730	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DS739_RS03730	COG0506	proline dehydrogenase activity
DS739_RS03745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DS739_RS03775	COG2096	Adenosyltransferase
DS739_RS03790	COG0277	FAD linked oxidase domain protein
DS739_RS03800	COG0009	L-threonylcarbamoyladenylate synthase
DS739_RS03810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DS739_RS03820	COG0656	L-ascorbic acid biosynthetic process
DS739_RS03830	COG1643	Atp-dependent helicase
DS739_RS03850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DS739_RS03855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DS739_RS03875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DS739_RS03880	COG0235	Class ii aldolase
DS739_RS03885	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DS739_RS03890	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DS739_RS03895	COG0196	riboflavin kinase activity
DS739_RS03900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DS739_RS03905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DS739_RS03915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DS739_RS03925	COG5006	permease, DMT superfamily
DS739_RS03930	COG0187	DNA topoisomerase II activity
DS739_RS03945	COG1959	2 iron, 2 sulfur cluster binding
DS739_RS03950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DS739_RS03955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DS739_RS03955	COG2885	chlorophyll binding
DS739_RS03965	COG0793	Belongs to the peptidase S41A family
DS739_RS03970	COG0557	exoribonuclease II activity
DS739_RS03975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DS739_RS03980	COG0758	DNA mediated transformation
DS739_RS03985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DS739_RS03990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DS739_RS03995	COG0540	Belongs to the ATCase OTCase family
DS739_RS04000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DS739_RS04005	COG2333	competence protein COMEC
DS739_RS04005	COG0658	competence protein
DS739_RS04010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DS739_RS04015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DS739_RS04025	COG0508	dehydrogenase complex catalyzes the overall conversion of
DS739_RS04045	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DS739_RS04060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS739_RS04095	COG3260	NADH ubiquinone oxidoreductase 20
DS739_RS04100	COG1183	phosphatidylcholine synthase activity
DS739_RS04105	COG0688	phosphatidylethanolamine metabolic process
DS739_RS04110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DS739_RS04120	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DS739_RS04120	COG2885	chlorophyll binding
DS739_RS04125	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DS739_RS04135	COG4974	Belongs to the 'phage' integrase family
DS739_RS04140	COG0825	malonyl-CoA metabolic process
DS739_RS04165	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DS739_RS04170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DS739_RS04175	COG0181	hydroxymethylbilane synthase activity
DS739_RS04185	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DS739_RS04190	COG0406	alpha-ribazole phosphatase activity
DS739_RS04200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DS739_RS04220	COG0408	coproporphyrinogen oxidase activity
DS739_RS04225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DS739_RS04225	COG2857	Cytochrome c1
DS739_RS04230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DS739_RS04230	COG2857	Cytochrome c1
DS739_RS04235	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DS739_RS04255	COG0778	Nitroreductase
DS739_RS04340	COG1518	maintenance of DNA repeat elements
DS739_RS04430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DS739_RS04520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DS739_RS04525	COG1902	pentaerythritol trinitrate reductase activity
DS739_RS04530	COG0640	Transcriptional regulator
DS739_RS04545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DS739_RS04555	COG0019	diaminopimelate decarboxylase activity
DS739_RS04560	COG0165	Argininosuccinate lyase
DS739_RS04580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DS739_RS04585	COG0237	dephospho-CoA kinase activity
DS739_RS04590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DS739_RS04610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DS739_RS04620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DS739_RS04625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DS739_RS04635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DS739_RS04640	COG0248	Ppx GppA phosphatase
DS739_RS04655	COG1121	(ABC) transporter
DS739_RS04680	COG1289	transmembrane transporter activity
DS739_RS04685	COG1289	transmembrane transporter activity
DS739_RS04705	COG3088	subunit of a heme lyase
DS739_RS04710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS739_RS04715	COG1138	Cytochrome C-type biogenesis protein
DS739_RS04720	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DS739_RS04725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DS739_RS04790	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DS739_RS04800	COG0477	Major facilitator Superfamily
DS739_RS04805	COG1322	Protein conserved in bacteria
DS739_RS04835	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DS739_RS04840	COG0081	regulation of translation
DS739_RS04845	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DS739_RS04850	COG0222	ribosome binding
DS739_RS04860	COG0085	RNA polymerase activity
DS739_RS04865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DS739_RS04870	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DS739_RS04875	COG0049	tRNA binding
DS739_RS04880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DS739_RS04885	COG0051	transcription antitermination factor activity, RNA binding
DS739_RS04890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DS739_RS04895	COG0088	Forms part of the polypeptide exit tunnel
DS739_RS04900	COG0089	rRNA binding
DS739_RS04905	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DS739_RS04910	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DS739_RS04915	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DS739_RS04920	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DS739_RS04925	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DS739_RS04930	COG0255	Belongs to the universal ribosomal protein uL29 family
DS739_RS04935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DS739_RS04940	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DS739_RS04945	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DS739_RS04950	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DS739_RS04955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DS739_RS04960	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DS739_RS04965	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DS739_RS04970	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DS739_RS04975	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DS739_RS04980	COG1841	ribosomal large subunit assembly
DS739_RS04985	COG0200	Binds to the 23S rRNA
DS739_RS04990	COG0201	protein transport
DS739_RS04995	COG0563	adenylate kinase activity
DS739_RS05000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DS739_RS05005	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DS739_RS05010	COG0202	RNA polymerase activity
DS739_RS05015	COG0203	ribosomal protein L17
DS739_RS05025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DS739_RS05030	COG1116	anion transmembrane transporter activity
DS739_RS05040	COG5487	UPF0391 membrane protein
DS739_RS05060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DS739_RS05070	COG3237	CsbD-like
DS739_RS05075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DS739_RS05080	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DS739_RS05105	COG0714	Associated with various cellular activities
DS739_RS05115	COG0617	tRNA 3'-terminal CCA addition
DS739_RS05120	COG1132	(ABC) transporter
DS739_RS05130	COG2814	Major facilitator Superfamily
DS739_RS05135	COG1051	belongs to the nudix hydrolase family
DS739_RS05145	COG0793	Belongs to the peptidase S41A family
DS739_RS05160	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DS739_RS05165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DS739_RS05170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DS739_RS05175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DS739_RS05180	COG0505	Belongs to the CarA family
DS739_RS05190	COG0358	DNA primase activity
DS739_RS05195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DS739_RS05205	COG0360	Binds together with S18 to 16S ribosomal RNA
DS739_RS05210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DS739_RS05215	COG0359	binds to the 23S rRNA
DS739_RS05220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DS739_RS05225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DS739_RS05255	COG1132	(ABC) transporter
DS739_RS05260	COG1802	Transcriptional regulator
DS739_RS05265	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DS739_RS05275	COG0850	regulation of cytokinetic process
DS739_RS05285	COG2081	HI0933 family
DS739_RS05290	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DS739_RS05300	COG0457	Tetratricopeptide repeat
DS739_RS05300	COG0859	PFAM glycosyl transferase family 9
DS739_RS05310	COG3781	membrane
DS739_RS05315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DS739_RS05330	COG2884	Cell division ATP-binding protein ftsE
DS739_RS05355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DS739_RS05360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DS739_RS05365	COG2166	iron-sulfur cluster assembly
DS739_RS05380	COG2010	Cytochrome c
DS739_RS05380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DS739_RS05385	COG0246	Mannitol dehydrogenase
DS739_RS05390	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DS739_RS05395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DS739_RS05400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DS739_RS05405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DS739_RS05405	COG0072	phenylalanine-tRNA ligase activity
DS739_RS05410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DS739_RS05415	COG0747	negative chemotaxis
DS739_RS05440	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DS739_RS05455	COG0473	3-isopropylmalate dehydrogenase activity
DS739_RS05460	COG0006	proline dipeptidase activity
DS739_RS05465	COG2264	protein methyltransferase activity
DS739_RS05470	COG0210	DNA helicase
DS739_RS05475	COG2003	Belongs to the UPF0758 family
DS739_RS05480	COG2003	Belongs to the UPF0758 family
DS739_RS05485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DS739_RS05510	COG0071	Belongs to the small heat shock protein (HSP20) family
DS739_RS05515	COG0254	rRNA binding
DS739_RS05520	COG1970	mechanosensitive ion channel activity
DS739_RS05530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DS739_RS05535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DS739_RS05545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS739_RS05545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DS739_RS05550	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS739_RS05560	COG0142	geranyltranstransferase activity
DS739_RS05565	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DS739_RS05570	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DS739_RS05585	COG2062	phosphohistidine phosphatase, SixA
DS739_RS05590	COG0287	Prephenate dehydrogenase
DS739_RS05590	COG1605	Chorismate mutase
DS739_RS05615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DS739_RS05625	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DS739_RS05635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DS739_RS05645	COG0729	surface antigen
DS739_RS05665	COG0322	excinuclease ABC activity
DS739_RS05680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DS739_RS05685	COG0314	molybdopterin synthase activity
DS739_RS05690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DS739_RS05695	COG0156	8-amino-7-oxononanoate synthase activity
DS739_RS05705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DS739_RS05705	COG4106	trans-aconitate 2-methyltransferase activity
DS739_RS05710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DS739_RS05715	COG0303	'Molybdopterin
DS739_RS05720	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DS739_RS05730	COG0148	phosphopyruvate hydratase activity
DS739_RS05750	COG2022	thiamine diphosphate biosynthetic process
DS739_RS05765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DS739_RS05770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DS739_RS05785	COG0076	glutamate decarboxylase activity
DS739_RS05800	COG0484	heat shock protein binding
DS739_RS05805	COG0271	Belongs to the BolA IbaG family
DS739_RS05815	COG0321	lipoyl(octanoyl) transferase activity
DS739_RS05835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DS739_RS05840	COG2226	methyltransferase
DS739_RS05865	COG2706	6-phosphogluconolactonase activity
DS739_RS05870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DS739_RS05875	COG0527	aspartate kinase activity
DS739_RS05880	COG2070	2-Nitropropane dioxygenase
DS739_RS05890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DS739_RS05900	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DS739_RS05910	COG2890	protein-(glutamine-N5) methyltransferase activity
DS739_RS05935	COG1968	undecaprenyl-diphosphatase activity
DS739_RS05940	COG0531	amino acid
DS739_RS05955	COG2951	lytic endotransglycosylase activity
DS739_RS05960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DS739_RS05965	COG1686	Belongs to the peptidase S11 family
DS739_RS05970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DS739_RS05985	COG0084	hydrolase, TatD family'
DS739_RS06000	COG0259	pyridoxamine-phosphate oxidase activity
DS739_RS06005	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DS739_RS06010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DS739_RS06015	COG1764	response to oxidative stress
DS739_RS06020	COG0579	oxidoreductase
DS739_RS06030	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DS739_RS06035	COG0602	queuosine metabolic process
DS739_RS06040	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DS739_RS06050	COG0175	sulfate reduction
DS739_RS06055	COG0175	sulfate reduction
DS739_RS06070	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DS739_RS06080	COG1519	Transferase
DS739_RS06085	COG1663	tetraacyldisaccharide 4'-kinase activity
DS739_RS06105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DS739_RS06110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DS739_RS06115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DS739_RS06125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DS739_RS06155	COG1278	Cold shock
DS739_RS06160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DS739_RS06165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DS739_RS06170	COG1605	Chorismate mutase
DS739_RS06170	COG0077	Prephenate dehydratase
DS739_RS06175	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DS739_RS06180	COG3474	cytochrome
DS739_RS06190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DS739_RS06195	COG0606	chelatase, subunit chli
DS739_RS06200	COG0626	cystathionine gamma-synthase activity
DS739_RS06205	COG2897	thiosulfate sulfurtransferase activity
DS739_RS06210	COG0628	permease
DS739_RS06220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DS739_RS06225	COG0792	nuclease activity
DS739_RS06235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DS739_RS06240	COG0271	Belongs to the BolA IbaG family
DS739_RS06245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DS739_RS06250	COG0047	phosphoribosylformylglycinamidine synthase activity
DS739_RS06260	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DS739_RS06265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DS739_RS06270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DS739_RS06275	COG0861	Integral membrane protein TerC family
DS739_RS06290	COG1546	Belongs to the CinA family
DS739_RS06305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DS739_RS06310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DS739_RS06315	COG0508	dehydrogenase complex catalyzes the overall conversion of
DS739_RS06320	COG0508	dehydrogenase complex catalyzes the overall conversion of
DS739_RS06320	COG0022	dehydrogenase e1 component
DS739_RS06325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DS739_RS06330	COG0315	cyclic pyranopterin monophosphate synthase activity
DS739_RS06335	COG0134	indole-3-glycerol-phosphate synthase activity
DS739_RS06340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DS739_RS06350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DS739_RS06360	COG0149	triose-phosphate isomerase activity
DS739_RS06370	COG0504	CTP synthase activity
DS739_RS06375	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DS739_RS06385	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DS739_RS06395	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DS739_RS06400	COG0268	Binds directly to 16S ribosomal RNA
DS739_RS06405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DS739_RS06410	COG2226	methyltransferase
DS739_RS06415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DS739_RS06420	COG0756	dUTP diphosphatase activity
DS739_RS06425	COG1176	ABC-type spermidine putrescine transport system, permease component I
DS739_RS06430	COG1116	anion transmembrane transporter activity
DS739_RS06435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DS739_RS06440	COG0525	valine-tRNA ligase activity
DS739_RS06455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DS739_RS06480	COG1028	Short-chain dehydrogenase reductase Sdr
DS739_RS06485	COG0456	acetyltransferase
DS739_RS06490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DS739_RS06495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DS739_RS06500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DS739_RS06510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DS739_RS06515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DS739_RS06525	COG1349	DNA-binding transcription factor activity
DS739_RS06540	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DS739_RS06545	COG4988	ABC transporter
DS739_RS06575	COG0488	(ABC) transporter
DS739_RS06590	COG2824	Alkylphosphonate utilization operon protein PhnA
DS739_RS06595	COG0814	amino acid
DS739_RS06605	COG0384	phenazine biosynthesis protein PhzF
DS739_RS06645	COG4206	TonB-dependent receptor
DS739_RS06655	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DS739_RS06680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DS739_RS06690	COG2233	PERMEase
DS739_RS06695	COG2351	hydroxyisourate hydrolase activity
DS739_RS06710	COG2072	flavoprotein involved in K transport
DS739_RS06720	COG0402	S-adenosylhomocysteine deaminase activity
DS739_RS06755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DS739_RS06760	COG1129	ABC transporter
DS739_RS06760	COG0842	Transport permease protein
DS739_RS06765	COG0842	Transport permease protein
DS739_RS06780	COG1657	PFAM Prenyltransferase squalene oxidase
DS739_RS06800	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DS739_RS06805	COG0753	catalase activity
DS739_RS06820	COG3459	Glycosyltransferase 36 associated
DS739_RS06855	COG4178	(ABC) transporter
DS739_RS06920	COG0477	Major facilitator Superfamily
DS739_RS06925	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DS739_RS06935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DS739_RS06940	COG1116	anion transmembrane transporter activity
DS739_RS06945	COG0864	Transcriptional regulator
DS739_RS06950	COG3665	Urea carboxylase-associated protein
DS739_RS06955	COG3665	Urea carboxylase-associated protein
DS739_RS06980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DS739_RS06990	COG1960	acyl-CoA dehydrogenase activity
DS739_RS07015	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DS739_RS07020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS739_RS07025	COG4558	Periplasmic binding protein
DS739_RS07035	COG1321	iron dependent repressor
DS739_RS07040	COG1914	H( )-stimulated, divalent metal cation uptake system
DS739_RS07055	COG0848	biopolymer transport protein
DS739_RS07175	COG4397	Mu-like prophage major head subunit gpT
DS739_RS07215	COG4373	Mu-like prophage FluMu protein gp28
DS739_RS07285	COG2842	Transposition protein
DS739_RS07290	COG2801	Transposase and inactivated derivatives
DS739_RS07330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DS739_RS07335	COG0384	phenazine biosynthesis protein PhzF
DS739_RS07340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DS739_RS07345	COG4974	Belongs to the 'phage' integrase family
DS739_RS07405	COG0523	cobalamin synthesis protein
DS739_RS07410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DS739_RS07415	COG0302	gtp cyclohydrolase
DS739_RS07425	COG0735	belongs to the Fur family
DS739_RS07430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DS739_RS07440	COG0640	Transcriptional regulator
DS739_RS07485	COG1301	dicarboxylic acid transport
DS739_RS07490	COG0500	methyltransferase
DS739_RS07495	COG2999	glutathione oxidoreductase activity
DS739_RS07500	COG2814	Major facilitator Superfamily
DS739_RS07505	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DS739_RS07555	COG0114	fumarate hydratase activity
DS739_RS07610	COG0628	permease
DS739_RS07630	COG0167	dihydroorotate dehydrogenase activity
DS739_RS07635	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DS739_RS07635	COG0674	pyruvate-flavodoxin oxidoreductase activity
DS739_RS07635	COG1013	pyruvate-flavodoxin oxidoreductase activity
DS739_RS07635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DS739_RS07640	COG0493	'glutamate synthase
DS739_RS07650	COG1971	Probably functions as a manganese efflux pump
DS739_RS07660	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DS739_RS07665	COG0746	molybdenum cofactor guanylyltransferase activity
DS739_RS07670	COG1763	Mo-molybdopterin cofactor biosynthetic process
DS739_RS07675	COG0303	'Molybdopterin
DS739_RS07680	COG3058	Necessary for formate dehydrogenase activity
DS739_RS07685	COG2864	formate dehydrogenase
DS739_RS07690	COG0437	4 iron, 4 sulfur cluster binding
DS739_RS07695	COG0243	molybdopterin cofactor binding
DS739_RS07695	COG3383	formate dehydrogenase (NAD+) activity
DS739_RS07705	COG0248	Ppx GppA phosphatase
DS739_RS07710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DS739_RS07715	COG1940	carbohydrate kinase activity
DS739_RS07720	COG0425	Belongs to the sulfur carrier protein TusA family
DS739_RS07725	COG1722	exodeoxyribonuclease VII activity
DS739_RS07730	COG0142	geranyltranstransferase activity
DS739_RS07735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DS739_RS07740	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DS739_RS07750	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DS739_RS07755	COG0137	argininosuccinate synthase activity
DS739_RS07760	COG0545	Peptidyl-prolyl cis-trans isomerase
DS739_RS07770	COG0180	Tryptophanyl-tRNA synthetase
DS739_RS07785	COG0745	RESPONSE REGULATOR receiver
DS739_RS07800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DS739_RS07800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DS739_RS07810	COG0747	negative chemotaxis
DS739_RS07815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DS739_RS07830	COG4608	Belongs to the ABC transporter superfamily
DS739_RS07835	COG2070	2-Nitropropane dioxygenase
DS739_RS07840	COG0671	phosphoesterase, PA-phosphatase related
DS739_RS07850	COG3511	phospholipase C
DS739_RS07870	COG1695	Transcriptional regulator
DS739_RS07880	COG1032	radical SAM domain protein
DS739_RS07895	COG0668	transmembrane transport
DS739_RS07910	COG1294	oxidase, subunit
DS739_RS07915	COG1271	oxidase subunit
DS739_RS07925	COG4988	ABC transporter
DS739_RS07930	COG3128	pkhd-type hydroxylase
DS739_RS07935	COG4774	siderophore transport
DS739_RS07950	COG0252	asparaginase activity
DS739_RS07960	COG2985	domain, Protein
DS739_RS07975	COG0488	(ABC) transporter
DS739_RS07990	COG1064	alcohol dehydrogenase
DS739_RS08005	COG2814	Major facilitator Superfamily
DS739_RS08020	COG1902	pentaerythritol trinitrate reductase activity
DS739_RS08070	COG0583	DNA-binding transcription factor activity
DS739_RS08100	COG1028	Short-chain dehydrogenase reductase Sdr
DS739_RS08105	COG0789	Transcriptional regulator
DS739_RS08125	COG2315	Protein conserved in bacteria
DS739_RS08130	COG4221	oxidoreductase activity
DS739_RS08185	COG0318	PFAM AMP-dependent synthetase and ligase
DS739_RS08195	COG0156	8-amino-7-oxononanoate synthase activity
DS739_RS08210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DS739_RS08235	COG0546	phosphoglycolate phosphatase activity
DS739_RS08240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DS739_RS08245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DS739_RS08260	COG0386	Belongs to the glutathione peroxidase family
DS739_RS08265	COG1136	(ABC) transporter
DS739_RS08275	COG0442	prolyl-tRNA aminoacylation
DS739_RS08285	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DS739_RS08295	COG1007	ATP synthesis coupled electron transport
DS739_RS08305	COG0713	ATP synthesis coupled electron transport
DS739_RS08315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DS739_RS08320	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DS739_RS08325	COG1034	ATP synthesis coupled electron transport
DS739_RS08335	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DS739_RS08340	COG0649	NAD binding
DS739_RS08345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DS739_RS08350	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DS739_RS08365	COG0776	regulation of translation
DS739_RS08375	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DS739_RS08380	COG0740	serine-type endopeptidase activity
DS739_RS08385	COG0544	peptidyl-prolyl cis-trans isomerase activity
DS739_RS08395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DS739_RS08395	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DS739_RS08405	COG0513	Belongs to the DEAD box helicase family
DS739_RS08415	COG0316	Belongs to the HesB IscA family
DS739_RS08420	COG2151	metal-sulfur cluster biosynthetic enzyme
DS739_RS08430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DS739_RS08435	COG0719	Fe-S assembly protein
DS739_RS08440	COG0396	ATPase activity
DS739_RS08445	COG0719	Fe-S assembly protein
DS739_RS08455	COG2733	membrane
DS739_RS08460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DS739_RS08470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DS739_RS08475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DS739_RS08485	COG5265	(ABC) transporter
DS739_RS08495	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DS739_RS08500	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DS739_RS08525	COG0612	Peptidase, M16
DS739_RS08530	COG0312	modulator of DNA gyrase
DS739_RS08545	COG0109	protoheme IX farnesyltransferase activity
DS739_RS08555	COG2226	methyltransferase
DS739_RS08575	COG0463	Glycosyl transferase, family 2
DS739_RS08580	COG1522	sequence-specific DNA binding
DS739_RS08585	COG0492	ferredoxin-NADP+ reductase activity
DS739_RS08590	COG0583	DNA-binding transcription factor activity
DS739_RS08595	COG4957	zinc ion binding
DS739_RS08600	COG0776	regulation of translation
DS739_RS08630	COG0776	regulation of translation
DS739_RS08635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DS739_RS08640	COG0416	fatty acid biosynthetic process
DS739_RS08645	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DS739_RS08665	COG0745	RESPONSE REGULATOR receiver
DS739_RS08670	COG1846	Transcriptional regulator
DS739_RS08680	COG0242	peptide deformylase activity
DS739_RS08685	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DS739_RS08690	COG0473	3-isopropylmalate dehydrogenase activity
DS739_RS08695	COG0066	3-isopropylmalate dehydratase activity
DS739_RS08700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DS739_RS08705	COG0335	large ribosomal subunit rRNA binding
DS739_RS08710	COG0336	Belongs to the RNA methyltransferase TrmD family
DS739_RS08715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DS739_RS08720	COG0228	four-way junction DNA binding
DS739_RS08745	COG0564	pseudouridine synthase activity
DS739_RS08750	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DS739_RS08760	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DS739_RS08770	COG3572	ergothioneine biosynthetic process
DS739_RS08775	COG2814	Major facilitator Superfamily
DS739_RS08780	COG1160	GTP binding
DS739_RS08805	COG0438	transferase activity, transferring glycosyl groups
DS739_RS08810	COG0367	asparagine synthase
DS739_RS08815	COG0354	folic acid binding
DS739_RS08820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DS739_RS08825	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DS739_RS08830	COG0659	secondary active sulfate transmembrane transporter activity
DS739_RS08855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DS739_RS08865	COG1051	belongs to the nudix hydrolase family
DS739_RS08870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DS739_RS08875	COG1923	regulation of RNA biosynthetic process
DS739_RS08880	COG2204	response regulator
DS739_RS08905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DS739_RS08905	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DS739_RS08910	COG0463	Glycosyl transferase, family 2
DS739_RS08955	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DS739_RS08970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DS739_RS08985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DS739_RS08990	COG0347	Belongs to the P(II) protein family
DS739_RS09000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DS739_RS09005	COG0586	Pfam SNARE associated Golgi protein
DS739_RS09015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DS739_RS09025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DS739_RS09030	COG0483	inositol monophosphate 1-phosphatase activity
DS739_RS09035	COG1199	ATP-dependent helicase activity
DS739_RS09040	COG1278	Cold shock
DS739_RS09045	COG0412	Dienelactone hydrolase
DS739_RS09050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DS739_RS09055	COG0459	protein refolding
DS739_RS09120	COG0004	ammonium transporteR
DS739_RS09140	COG4974	Belongs to the 'phage' integrase family
DS739_RS09150	COG1862	Preprotein translocase
DS739_RS09165	COG0494	nUDIX hydrolase
DS739_RS09185	COG0302	gtp cyclohydrolase
DS739_RS09195	COG0521	Mo-molybdopterin cofactor biosynthetic process
DS739_RS09225	COG1566	PFAM secretion protein HlyD family protein
DS739_RS09255	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DS739_RS09260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DS739_RS09260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DS739_RS09265	COG0307	riboflavin synthase, alpha
DS739_RS09275	COG2857	Cytochrome c1
DS739_RS09275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DS739_RS09280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DS739_RS09280	COG2857	Cytochrome c1
DS739_RS09285	COG0723	plastoquinol--plastocyanin reductase activity
DS739_RS09305	COG2252	PERMEase
DS739_RS09395	COG2026	Addiction module toxin, RelE StbE family
DS739_RS09540	COG2826	transposase and inactivated derivatives, IS30 family
DS739_RS09570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DS739_RS09575	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DS739_RS09580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DS739_RS09585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DS739_RS09595	COG3750	Belongs to the UPF0335 family
DS739_RS09600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DS739_RS09620	COG2001	Belongs to the MraZ family
DS739_RS09625	COG0275	rRNA processing
DS739_RS09640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DS739_RS09655	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DS739_RS09665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DS739_RS09670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DS739_RS09675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DS739_RS09680	COG1181	Belongs to the D-alanine--D-alanine ligase family
DS739_RS09685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DS739_RS09690	COG0849	cell division
DS739_RS09700	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DS739_RS09705	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DS739_RS09710	COG0497	DNA recombination
DS739_RS09715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DS739_RS09720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DS739_RS09720	COG0574	Belongs to the PEP-utilizing enzyme family
DS739_RS09725	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DS739_RS09745	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DS739_RS09760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DS739_RS09765	COG1335	isochorismatase
DS739_RS09775	COG2217	Heavy metal translocating P-type atpase
DS739_RS09785	COG2132	Multicopper oxidase
DS739_RS09795	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DS739_RS09805	COG0028	Belongs to the TPP enzyme family
DS739_RS09810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DS739_RS09815	COG0560	Phosphoserine phosphatase
DS739_RS09850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DS739_RS09855	COG0531	amino acid
DS739_RS09860	COG0113	porphobilinogen synthase activity
DS739_RS09865	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DS739_RS09870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DS739_RS09875	COG1381	Involved in DNA repair and RecF pathway recombination
DS739_RS09880	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DS739_RS09885	COG0052	Belongs to the universal ribosomal protein uS2 family
DS739_RS09910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DS739_RS09925	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DS739_RS09930	COG0251	oxidation-reduction process
DS739_RS09945	COG0436	Aminotransferase
DS739_RS09950	COG0436	Aminotransferase
DS739_RS09955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DS739_RS09975	COG3161	chorismate lyase activity
DS739_RS09980	COG1032	radical SAM domain protein
DS739_RS09985	COG0105	UTP biosynthetic process
DS739_RS09990	COG0488	(ABC) transporter
DS739_RS10000	COG0745	RESPONSE REGULATOR receiver
DS739_RS10015	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DS739_RS10020	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DS739_RS10055	COG0328	RNA-DNA hybrid ribonuclease activity
DS739_RS10060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DS739_RS10065	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DS739_RS10115	COG1530	ribonuclease E activity
DS739_RS10120	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DS739_RS10125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DS739_RS10130	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DS739_RS10135	COG0424	maF-like protein
DS739_RS10145	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DS739_RS10175	COG0277	FAD linked oxidase domain protein
DS739_RS10190	COG2308	Evidence 4 Homologs of previously reported genes of
DS739_RS10215	COG1309	transcriptional regulator
DS739_RS10220	COG1252	NADH dehydrogenase
DS739_RS10230	COG1012	belongs to the aldehyde dehydrogenase family
DS739_RS10235	COG2814	Major facilitator Superfamily
DS739_RS10245	COG0431	NADPH-dependent FMN reductase
DS739_RS10255	COG0583	DNA-binding transcription factor activity
DS739_RS10330	COG0583	DNA-binding transcription factor activity
DS739_RS10335	COG1289	transmembrane transporter activity
DS739_RS10360	COG4232	protein-disulfide reductase activity
DS739_RS10370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DS739_RS10375	COG0805	protein transport
DS739_RS10380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DS739_RS10385	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DS739_RS10390	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DS739_RS10400	COG0018	arginyl-trna synthetase
DS739_RS10405	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DS739_RS10410	COG0316	Belongs to the HesB IscA family
DS739_RS10415	COG0708	Exodeoxyribonuclease III
DS739_RS10440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DS739_RS10445	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
DS739_RS10455	COG0535	radical SAM domain protein
DS739_RS10465	COG0740	serine-type endopeptidase activity
DS739_RS10475	COG0436	Aminotransferase
DS739_RS10485	COG1494	fructose-1,6-bisphosphatase
DS739_RS10500	COG0564	pseudouridine synthase activity
DS739_RS10505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS739_RS10510	COG1120	ATPase activity
DS739_RS10515	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DS739_RS10520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DS739_RS10525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DS739_RS10525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DS739_RS10555	COG1294	oxidase, subunit
DS739_RS10560	COG1271	oxidase subunit
DS739_RS10575	COG1113	amino acid transport
DS739_RS10600	COG0135	phosphoribosylanthranilate isomerase activity
DS739_RS10605	COG0284	orotidine-5'-phosphate decarboxylase activity
DS739_RS10615	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DS739_RS10625	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DS739_RS10630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DS739_RS10640	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DS739_RS10665	COG3145	DNA-N1-methyladenine dioxygenase activity
DS739_RS10675	COG3620	sequence-specific DNA binding
DS739_RS10685	COG2011	ABC-type metal ion transport system permease component
DS739_RS10690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DS739_RS10700	COG0277	FAD linked oxidase domain protein
DS739_RS10705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DS739_RS10705	COG1648	precorrin-2 dehydrogenase activity
DS739_RS10735	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DS739_RS10800	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DS739_RS10810	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
DS739_RS10815	COG0732	type I restriction modification DNA specificity domain
DS739_RS10820	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DS739_RS10860	COG2337	Toxic component of a toxin-antitoxin (TA) module
DS739_RS10865	COG2336	PFAM SpoVT AbrB
DS739_RS10940	COG0848	biopolymer transport protein
DS739_RS10960	COG1301	dicarboxylic acid transport
DS739_RS10995	COG2814	Major facilitator Superfamily
DS739_RS11005	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DS739_RS11010	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DS739_RS11025	COG0778	Nitroreductase
DS739_RS11030	COG1492	cobalamin metabolic process
DS739_RS11045	COG1797	cobyrinic acid a,c-diamide synthase activity
DS739_RS11070	COG1289	transmembrane transporter activity
DS739_RS11075	COG1584	GPR1 FUN34 yaaH family protein
DS739_RS11080	COG1024	Enoyl-CoA hydratase
DS739_RS11085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DS739_RS11090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DS739_RS11105	COG0735	belongs to the Fur family
DS739_RS11120	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DS739_RS11140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DS739_RS11140	COG0519	Catalyzes the synthesis of GMP from XMP
DS739_RS11225	COG2814	Major facilitator Superfamily
DS739_RS11230	COG1196	nuclear chromosome segregation
DS739_RS11230	COG0739	heme binding
DS739_RS11230	COG0741	lytic transglycosylase activity
DS739_RS11250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DS739_RS11260	COG1496	oxidoreductase activity
DS739_RS11285	COG1742	UPF0060 membrane protein
DS739_RS11300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DS739_RS11315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DS739_RS11320	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DS739_RS11330	COG0363	glucosamine-6-phosphate deaminase activity
DS739_RS11335	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DS739_RS11340	COG3265	gluconokinase activity
DS739_RS11365	COG1063	alcohol dehydrogenase
DS739_RS11375	COG3158	transport of potassium into the cell
DS739_RS11380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DS739_RS11405	COG0583	DNA-binding transcription factor activity
DS739_RS11415	COG2814	Major facilitator Superfamily
DS739_RS11435	COG0411	ABC transporter
DS739_RS11455	COG0784	Response regulator, receiver
DS739_RS11455	COG2198	Histidine kinase
DS739_RS11455	COG5002	protein histidine kinase activity
DS739_RS11460	COG0745	RESPONSE REGULATOR receiver
DS739_RS11475	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DS739_RS11480	COG0830	nickel cation binding
DS739_RS11485	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DS739_RS11490	COG0804	urea catabolic process
DS739_RS11495	COG0832	Belongs to the urease beta subunit family
DS739_RS11500	COG0831	urea catabolic process
DS739_RS11505	COG0829	nickel cation binding
DS739_RS11510	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DS739_RS11515	COG3961	Belongs to the TPP enzyme family
DS739_RS11540	COG1393	Belongs to the ArsC family
DS739_RS11550	COG2818	Glycosylase
DS739_RS11560	COG0450	alkyl hydroperoxide reductase
DS739_RS11615	COG2271	Major facilitator Superfamily
DS739_RS11620	COG3473	Maleate cis-trans isomerase
DS739_RS11625	COG0596	Alpha beta hydrolase
DS739_RS11630	COG1335	isochorismatase
DS739_RS11635	COG2309	aminopeptidase activity
DS739_RS11640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DS739_RS11640	COG2010	Cytochrome c
DS739_RS11645	COG2080	2 iron, 2 sulfur cluster binding
DS739_RS11650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DS739_RS11655	COG1846	Transcriptional regulator
DS739_RS11665	COG4974	Belongs to the 'phage' integrase family
DS739_RS11695	COG4774	siderophore transport
DS739_RS11750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS739_RS11760	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DS739_RS11780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DS739_RS11780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DS739_RS11785	COG0509	glycine decarboxylation via glycine cleavage system
DS739_RS11790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DS739_RS11795	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DS739_RS11800	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DS739_RS11810	COG0583	DNA-binding transcription factor activity
DS739_RS11825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DS739_RS11830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DS739_RS11845	COG1185	polyribonucleotide nucleotidyltransferase activity
DS739_RS11850	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DS739_RS11855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DS739_RS11860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DS739_RS11865	COG1127	ABC transporter
DS739_RS11870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DS739_RS11870	COG3008	intermembrane lipid transfer
DS739_RS11905	COG2274	protein secretion by the type I secretion system
DS739_RS11915	COG1410	methionine synthase
DS739_RS11915	COG0646	methionine synthase
DS739_RS11930	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DS739_RS11940	COG3008	intermembrane lipid transfer
DS739_RS11945	COG2995	paraquat-inducible protein a
DS739_RS11955	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DS739_RS11960	COG0463	Glycosyl transferase, family 2
DS739_RS11965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DS739_RS11970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DS739_RS11975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DS739_RS11980	COG0356	it plays a direct role in the translocation of protons across the membrane
DS739_RS11990	COG0552	protein localization to endoplasmic reticulum
DS739_RS11995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DS739_RS12000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DS739_RS12005	COG0346	lactoylglutathione lyase activity
DS739_RS12015	COG0513	Belongs to the DEAD box helicase family
DS739_RS12035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DS739_RS12050	COG0704	Plays a role in the regulation of phosphate uptake
DS739_RS12055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DS739_RS12060	COG0581	inorganic phosphate transmembrane transporter activity
DS739_RS12065	COG0573	inorganic phosphate transmembrane transporter activity
DS739_RS12070	COG0129	dihydroxy-acid dehydratase activity
DS739_RS12105	COG0489	protein tyrosine kinase activity
DS739_RS12120	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DS739_RS12135	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DS739_RS12135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DS739_RS12150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DS739_RS12155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DS739_RS12160	COG1522	sequence-specific DNA binding
DS739_RS12165	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DS739_RS12170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DS739_RS12185	COG0779	Required for maturation of 30S ribosomal subunits
DS739_RS12195	COG0542	response to heat
DS739_RS12210	COG0765	amino acid transport
DS739_RS12215	COG1126	abc transporter atp-binding protein
DS739_RS12225	COG4133	protoheme IX ABC transporter activity
DS739_RS12245	COG1295	ribonuclease BN
DS739_RS12255	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DS739_RS12260	COG0511	ligase activity, forming carbon-carbon bonds
DS739_RS12265	COG0439	Biotin carboxylase
DS739_RS12270	COG2814	Major facilitator Superfamily
DS739_RS12275	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DS739_RS12325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DS739_RS12335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DS739_RS12340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DS739_RS12345	COG0154	amidase activity
DS739_RS12350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DS739_RS12360	COG1132	(ABC) transporter
DS739_RS12370	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DS739_RS12375	COG1194	a g-specific adenine glycosylase
DS739_RS12400	COG0495	leucyl-tRNA aminoacylation
DS739_RS12475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DS739_RS12485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DS739_RS12495	COG0590	tRNA wobble adenosine to inosine editing
DS739_RS12500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DS739_RS12505	COG1187	pseudouridine synthase activity
DS739_RS12510	COG0742	ribosomal rna small subunit methyltransferase
DS739_RS12515	COG0629	single-stranded DNA binding
DS739_RS12545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DS739_RS12550	COG0312	modulator of DNA gyrase
DS739_RS12555	COG0406	alpha-ribazole phosphatase activity
DS739_RS12575	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DS739_RS12580	COG1091	dTDP-4-dehydrorhamnose reductase activity
DS739_RS12590	COG1674	ftsk spoiiie
DS739_RS12595	COG0564	pseudouridine synthase activity
DS739_RS12610	COG0482	sulfurtransferase activity
DS739_RS12620	COG1104	cysteine desulfurase activity
DS739_RS12625	COG1104	cysteine desulfurase activity
DS739_RS12630	COG2945	thiolester hydrolase activity
DS739_RS12640	COG0215	cysteine-tRNA ligase activity
DS739_RS12650	COG0285	dihydrofolate synthase activity
DS739_RS12655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DS739_RS12665	COG1074	ATP-dependent DNA helicase activity
DS739_RS12670	COG2887	Belongs to the helicase family. UvrD subfamily
DS739_RS12675	COG0802	atpase or kinase
DS739_RS12680	COG0745	RESPONSE REGULATOR receiver
DS739_RS12695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DS739_RS12700	COG0037	tRNA processing
DS739_RS12710	COG2885	chlorophyll binding
DS739_RS12715	COG0823	Involved in the tonB-independent uptake of proteins
DS739_RS12725	COG0848	biopolymer transport protein
DS739_RS12735	COG0824	Thioesterase
DS739_RS12740	COG2255	four-way junction helicase activity
DS739_RS12745	COG0632	four-way junction helicase activity
DS739_RS12750	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DS739_RS12755	COG0217	transcriptional regulatory protein
DS739_RS12760	COG0653	protein targeting
DS739_RS12765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DS739_RS12770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DS739_RS12795	COG0484	heat shock protein binding
DS739_RS12830	COG0776	regulation of translation
DS739_RS12850	COG1216	Glycosyl transferase, family 2
DS739_RS12865	COG0131	Imidazoleglycerol-phosphate dehydratase
DS739_RS12870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DS739_RS12875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DS739_RS12880	COG0107	imidazoleglycerol-phosphate synthase activity
DS739_RS12885	COG0140	phosphoribosyl-ATP diphosphatase activity
DS739_RS12895	COG0778	Nitroreductase
DS739_RS13005	COG0357	Ribosomal RNA small subunit methyltransferase G
DS739_RS13010	COG0445	tRNA wobble uridine modification
DS739_RS13015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DS739_RS13020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DS739_RS13035	COG0582	viral genome integration into host DNA
DS739_RS13165	COG4626	Terminase
DS739_RS13165	COG1802	Transcriptional regulator
DS739_RS13255	COG4974	Belongs to the 'phage' integrase family
DS739_RS13290	COG4716	Myosin-crossreactive antigen
DS739_RS13300	COG2026	Addiction module toxin, RelE StbE family
DS739_RS13305	COG3077	Addiction module antitoxin, RelB DinJ family
DS739_RS13350	COG3189	MarR family transcriptional regulator
DS739_RS13380	COG4372	Transposase
DS739_RS13390	COG2963	transposase activity
DS739_RS13405	COG2026	Addiction module toxin, RelE StbE family
DS739_RS13410	COG3077	Addiction module antitoxin, RelB DinJ family
DS739_RS13415	COG1902	pentaerythritol trinitrate reductase activity
DS739_RS13455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DS739_RS13530	COG0642	Histidine kinase
DS739_RS13540	COG2223	nitrite transmembrane transporter activity
DS739_RS13550	COG2146	nitrite reductase [NAD(P)H] activity
DS739_RS13550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DS739_RS13570	COG2072	flavoprotein involved in K transport
DS739_RS13575	COG1012	belongs to the aldehyde dehydrogenase family
DS739_RS13585	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DS739_RS13660	COG1294	oxidase, subunit
DS739_RS13665	COG1271	oxidase subunit
DS739_RS13695	COG2336	PFAM SpoVT AbrB
DS739_RS13700	COG2337	Toxic component of a toxin-antitoxin (TA) module
DS739_RS13815	COG3189	MarR family transcriptional regulator
DS739_RS13820	COG3256	nitric oxide reductase
DS739_RS13830	COG1959	2 iron, 2 sulfur cluster binding
DS739_RS13905	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
DS739_RS13915	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DS739_RS13930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DS739_RS13935	COG0431	NADPH-dependent FMN reductase
DS739_RS13940	COG2072	flavoprotein involved in K transport
DS739_RS13945	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
DS739_RS13960	COG0583	DNA-binding transcription factor activity
DS739_RS13985	COG4115	mRNA cleavage
DS739_RS13990	COG2161	toxin-antitoxin pair type II binding
DS739_RS14010	COG1487	ribonuclease activity
DS739_RS14070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs