locus-tag	class	description
FLP30_RS00010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLP30_RS00010	COG0072	phenylalanine-tRNA ligase activity
FLP30_RS00015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FLP30_RS00020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FLP30_RS00025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FLP30_RS00035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FLP30_RS00040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FLP30_RS00065	COG2884	Cell division ATP-binding protein ftsE
FLP30_RS00080	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FLP30_RS00085	COG3781	membrane
FLP30_RS00105	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FLP30_RS00110	COG2081	HI0933 family
FLP30_RS00120	COG0850	regulation of cytokinetic process
FLP30_RS00125	COG2894	cell division
FLP30_RS00130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FLP30_RS00135	COG1802	Transcriptional regulator
FLP30_RS00140	COG1132	(ABC) transporter
FLP30_RS00160	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FLP30_RS00170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FLP30_RS00175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FLP30_RS00180	COG0359	binds to the 23S rRNA
FLP30_RS00185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FLP30_RS00190	COG0360	Binds together with S18 to 16S ribosomal RNA
FLP30_RS00200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLP30_RS00215	COG0505	Belongs to the CarA family
FLP30_RS00220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FLP30_RS00225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLP30_RS00230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FLP30_RS00275	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FLP30_RS00300	COG0438	transferase activity, transferring glycosyl groups
FLP30_RS00340	COG3706	GGDEF domain
FLP30_RS00345	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FLP30_RS00355	COG0793	Belongs to the peptidase S41A family
FLP30_RS00365	COG1051	belongs to the nudix hydrolase family
FLP30_RS00370	COG2814	Major facilitator Superfamily
FLP30_RS00375	COG1566	PFAM secretion protein HlyD family protein
FLP30_RS00380	COG1132	(ABC) transporter
FLP30_RS00385	COG0617	tRNA 3'-terminal CCA addition
FLP30_RS00395	COG0714	Associated with various cellular activities
FLP30_RS00420	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FLP30_RS00425	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLP30_RS00435	COG0477	Major facilitator Superfamily
FLP30_RS00440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLP30_RS00445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLP30_RS00460	COG5487	UPF0391 membrane protein
FLP30_RS00470	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FLP30_RS00485	COG0203	ribosomal protein L17
FLP30_RS00490	COG0202	RNA polymerase activity
FLP30_RS00495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FLP30_RS00500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FLP30_RS00505	COG0563	adenylate kinase activity
FLP30_RS00510	COG0201	protein transport
FLP30_RS00515	COG0200	Binds to the 23S rRNA
FLP30_RS00520	COG1841	ribosomal large subunit assembly
FLP30_RS00525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FLP30_RS00530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FLP30_RS00535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FLP30_RS00540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FLP30_RS00545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLP30_RS00550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FLP30_RS00555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FLP30_RS00560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FLP30_RS00565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FLP30_RS00570	COG0255	Belongs to the universal ribosomal protein uL29 family
FLP30_RS00575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FLP30_RS00580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FLP30_RS00585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FLP30_RS00590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLP30_RS00595	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FLP30_RS00600	COG0089	rRNA binding
FLP30_RS00605	COG0088	Forms part of the polypeptide exit tunnel
FLP30_RS00610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FLP30_RS00615	COG0051	transcription antitermination factor activity, RNA binding
FLP30_RS00620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FLP30_RS00625	COG0049	tRNA binding
FLP30_RS00630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FLP30_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLP30_RS00640	COG0085	RNA polymerase activity
FLP30_RS00645	COG0222	ribosome binding
FLP30_RS00650	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FLP30_RS00655	COG0081	regulation of translation
FLP30_RS00660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FLP30_RS00685	COG0745	RESPONSE REGULATOR receiver
FLP30_RS00695	COG0477	Major facilitator Superfamily
FLP30_RS00700	COG2202	Pas domain
FLP30_RS00700	COG2200	EAL domain
FLP30_RS00700	COG2199	diguanylate cyclase activity
FLP30_RS00750	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FLP30_RS00800	COG0306	phosphate transporter
FLP30_RS00815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FLP30_RS00850	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FLP30_RS00890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLP30_RS00900	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FLP30_RS00905	COG1138	Cytochrome C-type biogenesis protein
FLP30_RS00910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLP30_RS00915	COG3088	subunit of a heme lyase
FLP30_RS00935	COG1289	transmembrane transporter activity
FLP30_RS00970	COG0248	Ppx GppA phosphatase
FLP30_RS00975	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FLP30_RS00985	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FLP30_RS00990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FLP30_RS01000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLP30_RS01010	COG0438	transferase activity, transferring glycosyl groups
FLP30_RS01020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FLP30_RS01030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FLP30_RS01045	COG0165	Argininosuccinate lyase
FLP30_RS01050	COG0019	diaminopimelate decarboxylase activity
FLP30_RS01060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FLP30_RS01075	COG0640	Transcriptional regulator
FLP30_RS01080	COG1902	pentaerythritol trinitrate reductase activity
FLP30_RS01085	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FLP30_RS01095	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FLP30_RS01100	COG2857	Cytochrome c1
FLP30_RS01100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLP30_RS01105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLP30_RS01110	COG0408	coproporphyrinogen oxidase activity
FLP30_RS01125	COG1858	cytochrome C peroxidase
FLP30_RS01145	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FLP30_RS01155	COG0181	hydroxymethylbilane synthase activity
FLP30_RS01160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FLP30_RS01165	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FLP30_RS01170	COG2095	MarC family integral membrane protein
FLP30_RS01185	COG1546	Belongs to the CinA family
FLP30_RS01185	COG1058	Belongs to the CinA family
FLP30_RS01190	COG0825	malonyl-CoA metabolic process
FLP30_RS01195	COG4974	Belongs to the 'phage' integrase family
FLP30_RS01205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FLP30_RS01210	COG2885	chlorophyll binding
FLP30_RS01210	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FLP30_RS01220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FLP30_RS01225	COG0688	phosphatidylethanolamine metabolic process
FLP30_RS01230	COG1183	phosphatidylcholine synthase activity
FLP30_RS01235	COG3260	NADH ubiquinone oxidoreductase 20
FLP30_RS01265	COG2226	methyltransferase
FLP30_RS01270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLP30_RS01285	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FLP30_RS01290	COG0415	Belongs to the DNA photolyase family
FLP30_RS01305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLP30_RS01310	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLP30_RS01320	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FLP30_RS01325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLP30_RS01335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLP30_RS01340	COG0540	Belongs to the ATCase OTCase family
FLP30_RS01345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FLP30_RS01350	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FLP30_RS01360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLP30_RS01365	COG0557	exoribonuclease II activity
FLP30_RS01370	COG0793	Belongs to the peptidase S41A family
FLP30_RS01380	COG2885	chlorophyll binding
FLP30_RS01380	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FLP30_RS01385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLP30_RS01390	COG1959	2 iron, 2 sulfur cluster binding
FLP30_RS01405	COG0187	DNA topoisomerase II activity
FLP30_RS01415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FLP30_RS01425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FLP30_RS01430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FLP30_RS01435	COG0196	riboflavin kinase activity
FLP30_RS01440	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FLP30_RS01445	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FLP30_RS01450	COG0235	Class ii aldolase
FLP30_RS01455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLP30_RS01470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLP30_RS01475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FLP30_RS01495	COG1643	Atp-dependent helicase
FLP30_RS01500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLP30_RS01510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLP30_RS01520	COG0009	L-threonylcarbamoyladenylate synthase
FLP30_RS01530	COG0277	FAD linked oxidase domain protein
FLP30_RS01545	COG2096	Adenosyltransferase
FLP30_RS01565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLP30_RS01580	COG2855	membrane
FLP30_RS01600	COG0842	Transport permease protein
FLP30_RS01605	COG1129	ABC transporter
FLP30_RS01605	COG0842	Transport permease protein
FLP30_RS01625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FLP30_RS01630	COG1127	ABC transporter
FLP30_RS01635	COG3264	Mechanosensitive ion channel
FLP30_RS01635	COG1196	nuclear chromosome segregation
FLP30_RS01640	COG2985	domain, Protein
FLP30_RS01645	COG0076	glutamate decarboxylase activity
FLP30_RS01655	COG0305	Participates in initiation and elongation during chromosome replication
FLP30_RS01660	COG2942	2-epimerase
FLP30_RS01665	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FLP30_RS01665	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FLP30_RS01670	COG0194	GDP metabolic process
FLP30_RS01675	COG0300	oxidoreductase activity
FLP30_RS01680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FLP30_RS01685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLP30_RS01695	COG0517	IMP dehydrogenase activity
FLP30_RS01695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FLP30_RS01710	COG1137	ATPase activity
FLP30_RS01725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLP30_RS01740	COG0242	peptide deformylase activity
FLP30_RS01745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FLP30_RS01750	COG0101	tRNA pseudouridine synthase activity
FLP30_RS01760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLP30_RS01765	COG2171	N-acyltransferase activity
FLP30_RS01770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FLP30_RS01775	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FLP30_RS01780	COG0706	membrane insertase activity
FLP30_RS01785	COG0594	ribonuclease P activity
FLP30_RS01790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FLP30_RS01800	COG0346	lactoylglutathione lyase activity
FLP30_RS01805	COG3494	Protein of unknown function (DUF1009)
FLP30_RS01810	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FLP30_RS01815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FLP30_RS01820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FLP30_RS01830	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLP30_RS01835	COG0750	zinc metalloprotease
FLP30_RS01840	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FLP30_RS01850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FLP30_RS01855	COG0233	cytoplasmic translational termination
FLP30_RS01860	COG0528	UMP kinase activity
FLP30_RS01865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FLP30_RS01875	COG0681	Belongs to the peptidase S26 family
FLP30_RS01880	COG0736	holo-[acyl-carrier-protein] synthase activity
FLP30_RS01890	COG1758	RNA polymerase activity
FLP30_RS01915	COG0513	Belongs to the DEAD box helicase family
FLP30_RS01920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FLP30_RS01920	COG2813	Specifically methylates the guanine in position
FLP30_RS01925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FLP30_RS01930	COG0481	GTPase activity
FLP30_RS01955	COG0436	Aminotransferase
FLP30_RS01965	COG0538	isocitrate dehydrogenase activity
FLP30_RS01970	COG0492	ferredoxin-NADP+ reductase activity
FLP30_RS01990	COG1217	gtp-binding protein TYPA
FLP30_RS02015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLP30_RS02035	COG1297	OPT oligopeptide transporter protein
FLP30_RS02055	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FLP30_RS02065	COG1230	cation diffusion facilitator family transporter
FLP30_RS02085	COG0596	Alpha beta hydrolase
FLP30_RS02085	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLP30_RS02090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLP30_RS02095	COG3590	peptidase
FLP30_RS02105	COG1607	acyl-coa hydrolase
FLP30_RS02125	COG1054	Belongs to the UPF0176 family
FLP30_RS02210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FLP30_RS02225	COG1309	transcriptional regulator
FLP30_RS02230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLP30_RS02235	COG2971	BadF BadG BcrA BcrD
FLP30_RS02240	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FLP30_RS02245	COG1120	ATPase activity
FLP30_RS02250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLP30_RS02260	COG4206	TonB-dependent receptor
FLP30_RS02275	COG0025	NhaP-type Na H and K H
FLP30_RS02280	COG3956	TIGRFAM MazG family protein
FLP30_RS02285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FLP30_RS02290	COG1028	Short-chain dehydrogenase reductase Sdr
FLP30_RS02295	COG0604	alcohol dehydrogenase
FLP30_RS02310	COG1253	flavin adenine dinucleotide binding
FLP30_RS02320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FLP30_RS02330	COG0745	RESPONSE REGULATOR receiver
FLP30_RS02335	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FLP30_RS02340	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FLP30_RS02355	COG0159	tryptophan synthase activity
FLP30_RS02360	COG0133	tryptophan synthase activity
FLP30_RS02370	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FLP30_RS02390	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FLP30_RS02395	COG1396	sequence-specific DNA binding
FLP30_RS02400	COG3416	Protein conserved in bacteria
FLP30_RS02405	COG0752	glycyl-tRNA synthetase alpha subunit
FLP30_RS02415	COG5487	UPF0391 membrane protein
FLP30_RS02425	COG0138	bifunctional purine biosynthesis protein purh
FLP30_RS02430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FLP30_RS02435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FLP30_RS02440	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FLP30_RS02445	COG0484	heat shock protein binding
FLP30_RS02450	COG0443	Heat shock 70 kDa protein
FLP30_RS02455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FLP30_RS02460	COG0745	RESPONSE REGULATOR receiver
FLP30_RS02465	COG2205	protein histidine kinase activity
FLP30_RS02475	COG1660	Displays ATPase and GTPase activities
FLP30_RS02480	COG1678	Uncharacterized ACR, COG1678
FLP30_RS02485	COG2326	polyphosphate kinase activity
FLP30_RS02500	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FLP30_RS02505	COG1686	Belongs to the peptidase S11 family
FLP30_RS02510	COG0024	Methionine aminopeptidase
FLP30_RS02520	COG1509	lysine 2,3-aminomutase activity
FLP30_RS02540	COG0352	thiamine-phosphate diphosphorylase activity
FLP30_RS02570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLP30_RS02575	COG1692	metallophosphoesterase
FLP30_RS02585	COG0167	dihydroorotate dehydrogenase activity
FLP30_RS02595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLP30_RS02605	COG1121	(ABC) transporter
FLP30_RS02615	COG0735	belongs to the Fur family
FLP30_RS02635	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FLP30_RS02685	COG2814	Major facilitator Superfamily
FLP30_RS02690	COG0840	transmembrane signaling receptor activity
FLP30_RS02700	COG1064	alcohol dehydrogenase
FLP30_RS02705	COG2814	Major facilitator Superfamily
FLP30_RS02715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS02720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS02725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS02740	COG0747	negative chemotaxis
FLP30_RS02750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLP30_RS02760	COG4172	Belongs to the ABC transporter superfamily
FLP30_RS02765	COG3191	aminopeptidase activity
FLP30_RS02785	COG0697	spore germination
FLP30_RS02795	COG1289	transmembrane transporter activity
FLP30_RS02810	COG2985	domain, Protein
FLP30_RS02825	COG0583	DNA-binding transcription factor activity
FLP30_RS02830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLP30_RS02875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS02910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS02960	COG1252	NADH dehydrogenase
FLP30_RS02965	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS02975	COG1185	polyribonucleotide nucleotidyltransferase activity
FLP30_RS02980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FLP30_RS02985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FLP30_RS02995	COG1127	ABC transporter
FLP30_RS03000	COG3008	intermembrane lipid transfer
FLP30_RS03000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FLP30_RS03015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FLP30_RS03025	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FLP30_RS03035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLP30_RS03060	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS03070	COG0494	nUDIX hydrolase
FLP30_RS03075	COG2271	Major facilitator Superfamily
FLP30_RS03080	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FLP30_RS03095	COG1570	exodeoxyribonuclease VII activity
FLP30_RS03115	COG0778	Nitroreductase
FLP30_RS03135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FLP30_RS03140	COG3118	belongs to the thioredoxin family
FLP30_RS03150	COG2835	tetraacyldisaccharide 4'-kinase activity
FLP30_RS03160	COG2814	Major facilitator Superfamily
FLP30_RS03175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLP30_RS03180	COG1766	The M ring may be actively involved in energy transduction
FLP30_RS03185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLP30_RS03195	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLP30_RS03205	COG1338	Plays a role in the flagellum-specific transport system
FLP30_RS03230	COG1749	Flagellar hook protein flgE
FLP30_RS03235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLP30_RS03245	COG1987	bacterial-type flagellum assembly
FLP30_RS03250	COG1677	Flagellar hook-basal body complex protein FliE
FLP30_RS03260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLP30_RS03265	COG5006	permease, DMT superfamily
FLP30_RS03270	COG1558	bacterial-type flagellum-dependent cell motility
FLP30_RS03275	COG1815	bacterial-type flagellum-dependent cell motility
FLP30_RS03295	COG0745	RESPONSE REGULATOR receiver
FLP30_RS03305	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FLP30_RS03315	COG4786	Flagellar basal body rod
FLP30_RS03320	COG4786	Flagellar basal body rod
FLP30_RS03360	COG1360	Flagellar Motor Protein
FLP30_RS03365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FLP30_RS03400	COG1706	bacterial-type flagellum-dependent cell motility
FLP30_RS03425	COG1674	ftsk spoiiie
FLP30_RS03430	COG0564	pseudouridine synthase activity
FLP30_RS03445	COG0482	sulfurtransferase activity
FLP30_RS03460	COG1104	cysteine desulfurase activity
FLP30_RS03465	COG2945	thiolester hydrolase activity
FLP30_RS03470	COG1053	succinate dehydrogenase
FLP30_RS03470	COG3976	FMN-binding domain protein
FLP30_RS03480	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FLP30_RS03485	COG0745	RESPONSE REGULATOR receiver
FLP30_RS03490	COG2201	protein-glutamate methylesterase activity
FLP30_RS03495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FLP30_RS03500	COG0835	chemotaxis
FLP30_RS03505	COG0643	Histidine kinase
FLP30_RS03505	COG2198	Histidine kinase
FLP30_RS03510	COG0643	Histidine kinase
FLP30_RS03510	COG2198	Histidine kinase
FLP30_RS03510	COG0784	Response regulator, receiver
FLP30_RS03520	COG0840	transmembrane signaling receptor activity
FLP30_RS03535	COG0776	regulation of translation
FLP30_RS03540	COG3754	Rhamnan synthesis protein F
FLP30_RS03555	COG1215	transferase activity, transferring glycosyl groups
FLP30_RS03590	COG2999	glutathione oxidoreductase activity
FLP30_RS03595	COG0444	Belongs to the ABC transporter superfamily
FLP30_RS03600	COG4608	Belongs to the ABC transporter superfamily
FLP30_RS03615	COG5001	Diguanylate cyclase
FLP30_RS03615	COG3300	MHYT domain
FLP30_RS03620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FLP30_RS03635	COG5001	Diguanylate cyclase
FLP30_RS03635	COG3300	MHYT domain
FLP30_RS03645	COG0671	phosphoesterase, PA-phosphatase related
FLP30_RS03650	COG3128	pkhd-type hydroxylase
FLP30_RS03655	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FLP30_RS03655	COG2199	diguanylate cyclase activity
FLP30_RS03670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLP30_RS03675	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FLP30_RS03680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FLP30_RS03685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FLP30_RS03690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FLP30_RS03695	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FLP30_RS03700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FLP30_RS03705	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLP30_RS03735	COG0281	malic enzyme
FLP30_RS03745	COG0586	Pfam SNARE associated Golgi protein
FLP30_RS03750	COG1028	Short-chain dehydrogenase reductase Sdr
FLP30_RS03770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FLP30_RS03790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLP30_RS03800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLP30_RS03835	COG0670	Belongs to the BI1 family
FLP30_RS03855	COG1573	uracil-dna glycosylase
FLP30_RS03860	COG1289	transmembrane transporter activity
FLP30_RS03865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLP30_RS03880	COG1612	heme a metabolic process
FLP30_RS03905	COG0768	penicillin binding
FLP30_RS03910	COG0772	Belongs to the SEDS family
FLP30_RS03960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FLP30_RS03965	COG1420	regulation of RNA biosynthetic process
FLP30_RS03970	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FLP30_RS03975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FLP30_RS03980	COG0539	negative regulation of cytoplasmic translation
FLP30_RS03985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FLP30_RS03990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FLP30_RS04010	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FLP30_RS04015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FLP30_RS04040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLP30_RS04055	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FLP30_RS04070	COG0405	Gamma-glutamyltransferase
FLP30_RS04075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLP30_RS04075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FLP30_RS04120	COG0022	dehydrogenase e1 component
FLP30_RS04125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLP30_RS04145	COG2373	Large extracellular alpha-helical protein
FLP30_RS04150	COG4953	penicillin-binding protein 1C
FLP30_RS04160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLP30_RS04205	COG3189	MarR family transcriptional regulator
FLP30_RS04210	COG1017	nitric oxide dioxygenase activity
FLP30_RS04210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLP30_RS04215	COG1959	2 iron, 2 sulfur cluster binding
FLP30_RS04230	COG1607	acyl-coa hydrolase
FLP30_RS04250	COG0495	leucyl-tRNA aminoacylation
FLP30_RS04270	COG4774	siderophore transport
FLP30_RS04280	COG1595	DNA-templated transcription, initiation
FLP30_RS04295	COG4774	siderophore transport
FLP30_RS04315	COG0848	biopolymer transport protein
FLP30_RS04335	COG4303	Ethanolamine ammonia lyase large subunit
FLP30_RS04360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FLP30_RS04365	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLP30_RS04380	COG1346	cytolysis
FLP30_RS04385	COG4774	siderophore transport
FLP30_RS04435	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FLP30_RS04450	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS04455	COG0583	DNA-binding transcription factor activity
FLP30_RS04460	COG2072	flavoprotein involved in K transport
FLP30_RS04485	COG1999	signal sequence binding
FLP30_RS04550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLP30_RS04560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLP30_RS04570	COG0590	tRNA wobble adenosine to inosine editing
FLP30_RS04575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FLP30_RS04580	COG1187	pseudouridine synthase activity
FLP30_RS04585	COG0742	ribosomal rna small subunit methyltransferase
FLP30_RS04590	COG0629	single-stranded DNA binding
FLP30_RS04635	COG0312	modulator of DNA gyrase
FLP30_RS04640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLP30_RS04685	COG0484	heat shock protein binding
FLP30_RS04705	COG0668	transmembrane transport
FLP30_RS04710	COG1714	RDD family
FLP30_RS04715	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FLP30_RS04720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLP30_RS04725	COG0653	protein targeting
FLP30_RS04730	COG0217	transcriptional regulatory protein
FLP30_RS04735	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FLP30_RS04740	COG0632	four-way junction helicase activity
FLP30_RS04745	COG2255	four-way junction helicase activity
FLP30_RS04750	COG0824	Thioesterase
FLP30_RS04760	COG0848	biopolymer transport protein
FLP30_RS04770	COG0823	Involved in the tonB-independent uptake of proteins
FLP30_RS04775	COG2885	chlorophyll binding
FLP30_RS04785	COG0037	tRNA processing
FLP30_RS04800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLP30_RS04805	COG0351	phosphomethylpyrimidine kinase
FLP30_RS04805	COG0352	thiamine-phosphate diphosphorylase activity
FLP30_RS04810	COG0745	RESPONSE REGULATOR receiver
FLP30_RS04815	COG0802	atpase or kinase
FLP30_RS04820	COG2887	Belongs to the helicase family. UvrD subfamily
FLP30_RS04825	COG1074	ATP-dependent DNA helicase activity
FLP30_RS04835	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FLP30_RS04840	COG0285	dihydrofolate synthase activity
FLP30_RS04850	COG0215	cysteine-tRNA ligase activity
FLP30_RS04855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FLP30_RS04865	COG0424	maF-like protein
FLP30_RS04870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FLP30_RS04880	COG1981	membrane
FLP30_RS04915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLP30_RS04920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FLP30_RS04925	COG0445	tRNA wobble uridine modification
FLP30_RS04930	COG0357	Ribosomal RNA small subunit methyltransferase G
FLP30_RS04970	COG5265	(ABC) transporter
FLP30_RS04975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FLP30_RS04980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FLP30_RS05000	COG0038	chloride channel
FLP30_RS05005	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLP30_RS05005	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLP30_RS05010	COG0509	glycine decarboxylation via glycine cleavage system
FLP30_RS05015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FLP30_RS05025	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FLP30_RS05040	COG5001	Diguanylate cyclase
FLP30_RS05040	COG3300	MHYT domain
FLP30_RS05060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLP30_RS05105	COG0583	DNA-binding transcription factor activity
FLP30_RS05130	COG0513	Belongs to the DEAD box helicase family
FLP30_RS05145	COG0523	cobalamin synthesis protein
FLP30_RS05160	COG2824	Alkylphosphonate utilization operon protein PhnA
FLP30_RS05330	COG1301	dicarboxylic acid transport
FLP30_RS05345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLP30_RS05350	COG0154	amidase activity
FLP30_RS05355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLP30_RS05360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FLP30_RS05370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLP30_RS05385	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FLP30_RS05390	COG2814	Major facilitator Superfamily
FLP30_RS05395	COG0439	Biotin carboxylase
FLP30_RS05400	COG0511	ligase activity, forming carbon-carbon bonds
FLP30_RS05405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FLP30_RS05420	COG1295	ribonuclease BN
FLP30_RS05425	COG0019	diaminopimelate decarboxylase activity
FLP30_RS05435	COG4133	protoheme IX ABC transporter activity
FLP30_RS05445	COG1126	abc transporter atp-binding protein
FLP30_RS05450	COG0765	amino acid transport
FLP30_RS05475	COG0640	Transcriptional regulator
FLP30_RS05495	COG1028	Short-chain dehydrogenase reductase Sdr
FLP30_RS05500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLP30_RS05525	COG0542	response to heat
FLP30_RS05535	COG0779	Required for maturation of 30S ribosomal subunits
FLP30_RS05550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FLP30_RS05550	COG5373	membrane
FLP30_RS05555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FLP30_RS05560	COG1309	transcriptional regulator
FLP30_RS05565	COG1979	alcohol dehydrogenase
FLP30_RS05570	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS05575	COG1028	Short-chain dehydrogenase reductase Sdr
FLP30_RS05580	COG0583	DNA-binding transcription factor activity
FLP30_RS05590	COG4774	siderophore transport
FLP30_RS05600	COG0848	biopolymer transport protein
FLP30_RS05615	COG0129	dihydroxy-acid dehydratase activity
FLP30_RS05620	COG0573	inorganic phosphate transmembrane transporter activity
FLP30_RS05630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLP30_RS05635	COG0704	Plays a role in the regulation of phosphate uptake
FLP30_RS05650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FLP30_RS05680	COG0346	lactoylglutathione lyase activity
FLP30_RS05685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FLP30_RS05690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLP30_RS05695	COG0552	protein localization to endoplasmic reticulum
FLP30_RS05705	COG0356	it plays a direct role in the translocation of protons across the membrane
FLP30_RS05710	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLP30_RS05715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FLP30_RS05720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FLP30_RS05725	COG0463	Glycosyl transferase, family 2
FLP30_RS05745	COG2995	paraquat-inducible protein a
FLP30_RS05760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLP30_RS05765	COG1286	toxin biosynthetic process
FLP30_RS05775	COG1410	methionine synthase
FLP30_RS05775	COG0646	methionine synthase
FLP30_RS05820	COG0697	spore germination
FLP30_RS05825	COG0126	phosphoglycerate kinase activity
FLP30_RS05845	COG0156	8-amino-7-oxononanoate synthase activity
FLP30_RS05850	COG1522	sequence-specific DNA binding
FLP30_RS05855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLP30_RS05860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLP30_RS05875	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FLP30_RS05875	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FLP30_RS05890	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FLP30_RS05900	COG0489	protein tyrosine kinase activity
FLP30_RS05910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLP30_RS05930	COG0246	Mannitol dehydrogenase
FLP30_RS05940	COG0116	Belongs to the methyltransferase superfamily
FLP30_RS05940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FLP30_RS05945	COG0840	transmembrane signaling receptor activity
FLP30_RS05955	COG0753	catalase activity
FLP30_RS05960	COG4221	oxidoreductase activity
FLP30_RS05975	COG1742	UPF0060 membrane protein
FLP30_RS05990	COG1695	Transcriptional regulator
FLP30_RS05995	COG1301	dicarboxylic acid transport
FLP30_RS06005	COG0204	Acyl-transferase
FLP30_RS06015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLP30_RS06015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLP30_RS06025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLP30_RS06030	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FLP30_RS06040	COG0564	pseudouridine synthase activity
FLP30_RS06050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FLP30_RS06055	COG1494	fructose-1,6-bisphosphatase
FLP30_RS06065	COG0436	Aminotransferase
FLP30_RS06075	COG0740	serine-type endopeptidase activity
FLP30_RS06085	COG0697	spore germination
FLP30_RS06100	COG4772	TonB-dependent receptor
FLP30_RS06115	COG0488	(ABC) transporter
FLP30_RS06120	COG0535	radical SAM domain protein
FLP30_RS06130	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
FLP30_RS06135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FLP30_RS06145	COG0708	Exodeoxyribonuclease III
FLP30_RS06150	COG0316	Belongs to the HesB IscA family
FLP30_RS06155	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FLP30_RS06160	COG0018	arginyl-trna synthetase
FLP30_RS06170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FLP30_RS06175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FLP30_RS06180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLP30_RS06185	COG0805	protein transport
FLP30_RS06190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FLP30_RS06225	COG1764	response to oxidative stress
FLP30_RS06230	COG1846	Transcriptional regulator
FLP30_RS06240	COG2814	Major facilitator Superfamily
FLP30_RS06265	COG4993	Dehydrogenase
FLP30_RS06270	COG1741	Belongs to the pirin family
FLP30_RS06275	COG0583	DNA-binding transcription factor activity
FLP30_RS06285	COG1091	dTDP-4-dehydrorhamnose reductase activity
FLP30_RS06290	COG0583	DNA-binding transcription factor activity
FLP30_RS06315	COG3321	synthase
FLP30_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
FLP30_RS06315	COG0604	alcohol dehydrogenase
FLP30_RS06325	COG0131	Imidazoleglycerol-phosphate dehydratase
FLP30_RS06330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FLP30_RS06340	COG0107	imidazoleglycerol-phosphate synthase activity
FLP30_RS06345	COG0140	phosphoribosyl-ATP diphosphatase activity
FLP30_RS06405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLP30_RS06410	COG3158	transport of potassium into the cell
FLP30_RS06415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FLP30_RS06425	COG0604	alcohol dehydrogenase
FLP30_RS06440	COG3265	gluconokinase activity
FLP30_RS06445	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FLP30_RS06450	COG0363	glucosamine-6-phosphate deaminase activity
FLP30_RS06455	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FLP30_RS06460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FLP30_RS06475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLP30_RS06520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FLP30_RS06535	COG1196	nuclear chromosome segregation
FLP30_RS06535	COG0741	lytic transglycosylase activity
FLP30_RS06535	COG0739	heme binding
FLP30_RS06560	COG0519	Catalyzes the synthesis of GMP from XMP
FLP30_RS06560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FLP30_RS06585	COG2818	Glycosylase
FLP30_RS06590	COG0640	Transcriptional regulator
FLP30_RS06595	COG0450	alkyl hydroperoxide reductase
FLP30_RS06605	COG0730	response to heat
FLP30_RS06610	COG0659	secondary active sulfate transmembrane transporter activity
FLP30_RS06615	COG1393	Belongs to the ArsC family
FLP30_RS06620	COG0326	Molecular chaperone. Has ATPase activity
FLP30_RS06645	COG2267	carboxylic ester hydrolase activity
FLP30_RS06650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS06655	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS06670	COG1176	ABC-type spermidine putrescine transport system, permease component I
FLP30_RS06675	COG1177	transmembrane transport
FLP30_RS06680	COG3842	ATPase activity
FLP30_RS06690	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS06695	COG3842	ATPase activity
FLP30_RS06700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FLP30_RS06705	COG1176	ABC-type spermidine putrescine transport system, permease component I
FLP30_RS06710	COG1177	transmembrane transport
FLP30_RS06725	COG1393	Belongs to the ArsC family
FLP30_RS06745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FLP30_RS06745	COG1648	precorrin-2 dehydrogenase activity
FLP30_RS06755	COG2207	Transcriptional regulator
FLP30_RS06760	COG4303	Ethanolamine ammonia lyase large subunit
FLP30_RS06765	COG4302	ethanolamine ammonia-lyase activity
FLP30_RS06785	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLP30_RS06785	COG1024	Enoyl-CoA hydratase
FLP30_RS06790	COG1584	GPR1 FUN34 yaaH family protein
FLP30_RS06795	COG1289	transmembrane transporter activity
FLP30_RS06805	COG0406	alpha-ribazole phosphatase activity
FLP30_RS06815	COG0778	Nitroreductase
FLP30_RS06820	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FLP30_RS06825	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FLP30_RS06865	COG0110	maltose O-acetyltransferase activity
FLP30_RS06870	COG0384	phenazine biosynthesis protein PhzF
FLP30_RS06880	COG1671	Belongs to the UPF0178 family
FLP30_RS06905	COG0583	DNA-binding transcription factor activity
FLP30_RS06920	COG4774	siderophore transport
FLP30_RS06945	COG2983	Belongs to the UPF0260 family
FLP30_RS06960	COG3842	ATPase activity
FLP30_RS06975	COG1846	Transcriptional regulator
FLP30_RS06985	COG1566	PFAM secretion protein HlyD family protein
FLP30_RS06990	COG1538	Outer membrane efflux protein
FLP30_RS07000	COG1657	PFAM Prenyltransferase squalene oxidase
FLP30_RS07005	COG1233	COG1233 Phytoene dehydrogenase and related
FLP30_RS07010	COG1562	ergosterol biosynthetic process
FLP30_RS07015	COG1562	ergosterol biosynthetic process
FLP30_RS07025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLP30_RS07035	COG0287	Prephenate dehydrogenase
FLP30_RS07045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FLP30_RS07055	COG0450	alkyl hydroperoxide reductase
FLP30_RS07060	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLP30_RS07070	COG2353	YceI-like domain
FLP30_RS07075	COG3384	dioxygenase
FLP30_RS07080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FLP30_RS07090	COG0488	(ABC) transporter
FLP30_RS07110	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FLP30_RS07120	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FLP30_RS07125	COG0343	queuine tRNA-ribosyltransferase activity
FLP30_RS07130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FLP30_RS07140	COG1881	PFAM PEBP family protein
FLP30_RS07150	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FLP30_RS07190	COG1877	trehalose-phosphatase activity
FLP30_RS07195	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FLP30_RS07205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLP30_RS07210	COG2218	PFAM glutamate synthase alpha subunit domain protein
FLP30_RS07215	COG0069	glutamate synthase activity
FLP30_RS07225	COG0004	ammonium transporteR
FLP30_RS07250	COG0840	transmembrane signaling receptor activity
FLP30_RS07260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLP30_RS07265	COG4311	Sarcosine oxidase, delta subunit
FLP30_RS07270	COG0446	pyridine nucleotide-disulphide oxidoreductase
FLP30_RS07270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FLP30_RS07285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FLP30_RS07300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FLP30_RS07310	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FLP30_RS07345	COG0556	nucleotide-excision repair
FLP30_RS07355	COG0612	Peptidase, M16
FLP30_RS07370	COG1215	transferase activity, transferring glycosyl groups
FLP30_RS07380	COG1396	sequence-specific DNA binding
FLP30_RS07380	COG3800	Transcriptional regulator
FLP30_RS07385	COG2079	MmgE PrpD family protein
FLP30_RS07390	COG0372	Belongs to the citrate synthase family
FLP30_RS07395	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FLP30_RS07400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLP30_RS07410	COG2309	aminopeptidase activity
FLP30_RS07425	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FLP30_RS07430	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FLP30_RS07435	COG0193	aminoacyl-tRNA hydrolase activity
FLP30_RS07440	COG0012	GTP binding
FLP30_RS07445	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FLP30_RS07450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FLP30_RS07455	COG0799	negative regulation of ribosome biogenesis
FLP30_RS07460	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FLP30_RS07465	COG0277	FAD linked oxidase domain protein
FLP30_RS07470	COG0277	FAD linked oxidase domain protein
FLP30_RS07475	COG0247	lactate metabolic process
FLP30_RS07480	COG0247	lactate metabolic process
FLP30_RS07485	COG1139	Iron-sulfur cluster binding protein
FLP30_RS07495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLP30_RS07500	COG0717	Belongs to the dCTP deaminase family
FLP30_RS07515	COG3394	polysaccharide catabolic process
FLP30_RS07535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FLP30_RS07540	COG0535	radical SAM domain protein
FLP30_RS07545	COG1253	flavin adenine dinucleotide binding
FLP30_RS07550	COG0741	lytic transglycosylase activity
FLP30_RS07555	COG1573	uracil-dna glycosylase
FLP30_RS07565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FLP30_RS07570	COG3290	protein histidine kinase activity
FLP30_RS07570	COG0840	transmembrane signaling receptor activity
FLP30_RS07590	COG0534	Mate efflux family protein
FLP30_RS07605	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLP30_RS07630	COG4964	Belongs to the GSP D family
FLP30_RS07675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLP30_RS07680	COG4771	TonB-dependent receptor
FLP30_RS07690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLP30_RS07700	COG0864	Transcriptional regulator
FLP30_RS07710	COG3665	Urea carboxylase-associated protein
FLP30_RS07715	COG0439	Biotin carboxylase
FLP30_RS07730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FLP30_RS07735	COG0840	transmembrane signaling receptor activity
FLP30_RS07740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FLP30_RS07770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FLP30_RS07775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FLP30_RS07790	COG0284	orotidine-5'-phosphate decarboxylase activity
FLP30_RS07795	COG0135	phosphoribosylanthranilate isomerase activity
FLP30_RS07835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLP30_RS07860	COG2144	transferase activity, transferring acyl groups
FLP30_RS07875	COG2072	flavoprotein involved in K transport
FLP30_RS07890	COG4774	siderophore transport
FLP30_RS07900	COG0778	Nitroreductase
FLP30_RS07920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FLP30_RS07930	COG0424	maF-like protein
FLP30_RS07935	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FLP30_RS07940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FLP30_RS07945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FLP30_RS07950	COG1530	ribonuclease E activity
FLP30_RS08000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FLP30_RS08005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLP30_RS08010	COG0328	RNA-DNA hybrid ribonuclease activity
FLP30_RS08020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLP30_RS08035	COG0859	PFAM glycosyl transferase family 9
FLP30_RS08040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLP30_RS08045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FLP30_RS08060	COG2205	protein histidine kinase activity
FLP30_RS08075	COG2814	Major facilitator Superfamily
FLP30_RS08080	COG0488	(ABC) transporter
FLP30_RS08085	COG0105	UTP biosynthetic process
FLP30_RS08090	COG1032	radical SAM domain protein
FLP30_RS08115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLP30_RS08120	COG0436	Aminotransferase
FLP30_RS08125	COG0436	Aminotransferase
FLP30_RS08140	COG0251	oxidation-reduction process
FLP30_RS08145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FLP30_RS08170	COG0052	Belongs to the universal ribosomal protein uS2 family
FLP30_RS08175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FLP30_RS08180	COG1381	Involved in DNA repair and RecF pathway recombination
FLP30_RS08185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLP30_RS08210	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FLP30_RS08215	COG0113	porphobilinogen synthase activity
FLP30_RS08220	COG0531	amino acid
FLP30_RS08225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FLP30_RS08235	COG0513	Belongs to the DEAD box helicase family
FLP30_RS08250	COG0560	Phosphoserine phosphatase
FLP30_RS08255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FLP30_RS08260	COG0028	Belongs to the TPP enzyme family
FLP30_RS08270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FLP30_RS08275	COG1937	Protein conserved in bacteria
FLP30_RS08285	COG2132	Multicopper oxidase
FLP30_RS08305	COG1335	isochorismatase
FLP30_RS08310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLP30_RS08325	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FLP30_RS08345	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FLP30_RS08350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLP30_RS08350	COG0574	Belongs to the PEP-utilizing enzyme family
FLP30_RS08355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FLP30_RS08365	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLP30_RS08370	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FLP30_RS08380	COG0849	cell division
FLP30_RS08385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FLP30_RS08390	COG1181	Belongs to the D-alanine--D-alanine ligase family
FLP30_RS08395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FLP30_RS08400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FLP30_RS08405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FLP30_RS08415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLP30_RS08420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLP30_RS08425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FLP30_RS08430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLP30_RS08445	COG0275	rRNA processing
FLP30_RS08450	COG2001	Belongs to the MraZ family
FLP30_RS08460	COG0657	acetylesterase activity
FLP30_RS08470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FLP30_RS08475	COG3750	Belongs to the UPF0335 family
FLP30_RS08490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FLP30_RS08495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FLP30_RS08500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FLP30_RS08505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FLP30_RS08520	COG4977	sequence-specific DNA binding
FLP30_RS08520	COG1917	Cupin 2, conserved barrel domain protein
FLP30_RS08525	COG4221	oxidoreductase activity
FLP30_RS08530	COG0583	DNA-binding transcription factor activity
FLP30_RS08540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLP30_RS08550	COG4771	TonB-dependent receptor
FLP30_RS08555	COG2375	cellular response to nickel ion
FLP30_RS08555	COG1132	(ABC) transporter
FLP30_RS08570	COG1321	iron dependent repressor
FLP30_RS08575	COG1914	H( )-stimulated, divalent metal cation uptake system
FLP30_RS08600	COG4988	ABC transporter
FLP30_RS08605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FLP30_RS08610	COG1271	oxidase subunit
FLP30_RS08615	COG1294	oxidase, subunit
FLP30_RS08630	COG2308	Evidence 4 Homologs of previously reported genes of
FLP30_RS08650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLP30_RS08665	COG0436	Aminotransferase
FLP30_RS08675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLP30_RS08675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FLP30_RS08690	COG0745	RESPONSE REGULATOR receiver
FLP30_RS08695	COG0745	RESPONSE REGULATOR receiver
FLP30_RS08700	COG2205	protein histidine kinase activity
FLP30_RS08705	COG4774	siderophore transport
FLP30_RS08725	COG0235	Class ii aldolase
FLP30_RS08730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLP30_RS08755	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS08765	COG4638	Rieske (2fe-2S)
FLP30_RS08790	COG0154	amidase activity
FLP30_RS08810	COG2326	polyphosphate kinase activity
FLP30_RS08880	COG0629	single-stranded DNA binding
FLP30_RS08910	COG3750	Belongs to the UPF0335 family
FLP30_RS09130	COG0180	Tryptophanyl-tRNA synthetase
FLP30_RS09140	COG0545	Peptidyl-prolyl cis-trans isomerase
FLP30_RS09145	COG0137	argininosuccinate synthase activity
FLP30_RS09150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FLP30_RS09160	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FLP30_RS09165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FLP30_RS09170	COG0142	geranyltranstransferase activity
FLP30_RS09175	COG1722	exodeoxyribonuclease VII activity
FLP30_RS09180	COG0425	Belongs to the sulfur carrier protein TusA family
FLP30_RS09185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FLP30_RS09215	COG0438	transferase activity, transferring glycosyl groups
FLP30_RS09235	COG1137	ATPase activity
FLP30_RS09240	COG0438	transferase activity, transferring glycosyl groups
FLP30_RS09255	COG0667	Aldo Keto reductase
FLP30_RS09260	COG1741	Belongs to the pirin family
FLP30_RS09280	COG0583	DNA-binding transcription factor activity
FLP30_RS09295	COG1113	amino acid transport
FLP30_RS09310	COG1929	Belongs to the glycerate kinase type-1 family
FLP30_RS09325	COG0723	plastoquinol--plastocyanin reductase activity
FLP30_RS09335	COG0307	riboflavin synthase, alpha
FLP30_RS09340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLP30_RS09340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLP30_RS09345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FLP30_RS09380	COG1566	PFAM secretion protein HlyD family protein
FLP30_RS09400	COG0302	gtp cyclohydrolase
FLP30_RS09415	COG0494	nUDIX hydrolase
FLP30_RS09430	COG1862	Preprotein translocase
FLP30_RS09440	COG4974	Belongs to the 'phage' integrase family
FLP30_RS09460	COG0004	ammonium transporteR
FLP30_RS09465	COG0347	Belongs to the P(II) protein family
FLP30_RS09470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLP30_RS09475	COG1045	serine acetyltransferase
FLP30_RS09480	COG0459	protein refolding
FLP30_RS09485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FLP30_RS09490	COG1278	Cold shock
FLP30_RS09495	COG1199	ATP-dependent helicase activity
FLP30_RS09500	COG0483	inositol monophosphate 1-phosphatase activity
FLP30_RS09505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FLP30_RS09545	COG4774	siderophore transport
FLP30_RS09555	COG0640	Transcriptional regulator
FLP30_RS09585	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS09615	COG1408	metallophosphoesterase
FLP30_RS09635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLP30_RS09640	COG0402	S-adenosylhomocysteine deaminase activity
FLP30_RS09650	COG1414	Transcriptional regulator
FLP30_RS09665	COG0633	Ferredoxin
FLP30_RS09690	COG4948	Mandelate Racemase Muconate Lactonizing
FLP30_RS09705	COG2124	cytochrome p450
FLP30_RS09710	COG1028	Short-chain dehydrogenase reductase Sdr
FLP30_RS09720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FLP30_RS09725	COG1304	FMN binding
FLP30_RS09730	COG1304	FMN binding
FLP30_RS09735	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FLP30_RS09740	COG0747	negative chemotaxis
FLP30_RS09745	COG1414	Transcriptional regulator
FLP30_RS09785	COG0667	Aldo Keto reductase
FLP30_RS09790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS09805	COG4771	TonB-dependent receptor
FLP30_RS09815	COG3961	Belongs to the TPP enzyme family
FLP30_RS09830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLP30_RS09835	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FLP30_RS09855	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FLP30_RS09855	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FLP30_RS09880	COG2204	response regulator
FLP30_RS09885	COG1923	regulation of RNA biosynthetic process
FLP30_RS09890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FLP30_RS09895	COG0542	response to heat
FLP30_RS09900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FLP30_RS09915	COG0659	secondary active sulfate transmembrane transporter activity
FLP30_RS09920	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FLP30_RS09925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FLP30_RS09930	COG0354	folic acid binding
FLP30_RS09935	COG0367	asparagine synthase
FLP30_RS09965	COG1160	GTP binding
FLP30_RS09970	COG2814	Major facilitator Superfamily
FLP30_RS09995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FLP30_RS10000	COG0564	pseudouridine synthase activity
FLP30_RS10020	COG0228	four-way junction DNA binding
FLP30_RS10025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FLP30_RS10030	COG0336	Belongs to the RNA methyltransferase TrmD family
FLP30_RS10035	COG0335	large ribosomal subunit rRNA binding
FLP30_RS10040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FLP30_RS10045	COG0066	3-isopropylmalate dehydratase activity
FLP30_RS10050	COG0473	3-isopropylmalate dehydrogenase activity
FLP30_RS10055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FLP30_RS10060	COG0242	peptide deformylase activity
FLP30_RS10075	COG0745	RESPONSE REGULATOR receiver
FLP30_RS10095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FLP30_RS10100	COG0416	fatty acid biosynthetic process
FLP30_RS10105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLP30_RS10125	COG0628	permease
FLP30_RS10130	COG0728	peptidoglycan biosynthetic process
FLP30_RS10135	COG1573	uracil-dna glycosylase
FLP30_RS10140	COG0776	regulation of translation
FLP30_RS10145	COG4957	zinc ion binding
FLP30_RS10150	COG0583	DNA-binding transcription factor activity
FLP30_RS10155	COG0492	ferredoxin-NADP+ reductase activity
FLP30_RS10160	COG1522	sequence-specific DNA binding
FLP30_RS10165	COG0463	Glycosyl transferase, family 2
FLP30_RS10190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLP30_RS10195	COG0109	protoheme IX farnesyltransferase activity
FLP30_RS10205	COG0312	modulator of DNA gyrase
FLP30_RS10210	COG0612	Peptidase, M16
FLP30_RS10225	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FLP30_RS10235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FLP30_RS10240	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FLP30_RS10250	COG5265	(ABC) transporter
FLP30_RS10260	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FLP30_RS10270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FLP30_RS10280	COG2733	membrane
FLP30_RS10290	COG0719	Fe-S assembly protein
FLP30_RS10295	COG0396	ATPase activity
FLP30_RS10300	COG0719	Fe-S assembly protein
FLP30_RS10305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLP30_RS10310	COG2151	metal-sulfur cluster biosynthetic enzyme
FLP30_RS10315	COG0316	Belongs to the HesB IscA family
FLP30_RS10320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLP30_RS10325	COG0513	Belongs to the DEAD box helicase family
FLP30_RS10335	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FLP30_RS10335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FLP30_RS10345	COG0544	peptidyl-prolyl cis-trans isomerase activity
FLP30_RS10350	COG0740	serine-type endopeptidase activity
FLP30_RS10355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FLP30_RS10365	COG0776	regulation of translation
FLP30_RS10375	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FLP30_RS10380	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FLP30_RS10385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FLP30_RS10390	COG0649	NAD binding
FLP30_RS10395	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FLP30_RS10405	COG1034	ATP synthesis coupled electron transport
FLP30_RS10410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FLP30_RS10425	COG0713	ATP synthesis coupled electron transport
FLP30_RS10435	COG1007	ATP synthesis coupled electron transport
FLP30_RS10445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FLP30_RS10455	COG0442	prolyl-tRNA aminoacylation
FLP30_RS10465	COG1136	(ABC) transporter
FLP30_RS10470	COG0386	Belongs to the glutathione peroxidase family
FLP30_RS10490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLP30_RS10495	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLP30_RS10515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FLP30_RS10540	COG0318	PFAM AMP-dependent synthetase and ligase
FLP30_RS10585	COG0640	Transcriptional regulator
FLP30_RS10595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLP30_RS10600	COG0735	belongs to the Fur family
FLP30_RS10610	COG0302	gtp cyclohydrolase
FLP30_RS10615	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FLP30_RS10620	COG0523	cobalamin synthesis protein
FLP30_RS10625	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FLP30_RS10640	COG0215	cysteine-tRNA ligase activity
FLP30_RS10670	COG0776	regulation of translation
FLP30_RS10690	COG4974	Belongs to the 'phage' integrase family
FLP30_RS10695	COG1595	DNA-templated transcription, initiation
FLP30_RS10705	COG4774	siderophore transport
FLP30_RS10730	COG0583	DNA-binding transcription factor activity
FLP30_RS10745	COG2130	NADP-dependent
FLP30_RS10750	COG1234	tRNA 3'-trailer cleavage
FLP30_RS10755	COG0300	oxidoreductase activity
FLP30_RS10760	COG0583	DNA-binding transcription factor activity
FLP30_RS10795	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FLP30_RS10835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLP30_RS10865	COG4206	TonB-dependent receptor
FLP30_RS10890	COG4774	siderophore transport
FLP30_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
FLP30_RS10900	COG2207	Transcriptional regulator
FLP30_RS10925	COG3145	DNA-N1-methyladenine dioxygenase activity
FLP30_RS10940	COG0697	spore germination
FLP30_RS10945	COG1522	sequence-specific DNA binding
FLP30_RS10950	COG1960	acyl-CoA dehydrogenase activity
FLP30_RS10955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLP30_RS10960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLP30_RS10965	COG1116	anion transmembrane transporter activity
FLP30_RS10970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS10975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS10980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS11035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLP30_RS11040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP30_RS11045	COG0583	DNA-binding transcription factor activity
FLP30_RS11090	COG0443	Heat shock 70 kDa protein
FLP30_RS11095	COG0840	transmembrane signaling receptor activity
FLP30_RS11100	COG1090	epimerase
FLP30_RS11110	COG1959	2 iron, 2 sulfur cluster binding
FLP30_RS11135	COG1464	Belongs to the NlpA lipoprotein family
FLP30_RS11140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLP30_RS11145	COG2011	ABC-type metal ion transport system permease component
FLP30_RS11160	COG2188	Transcriptional regulator
FLP30_RS11175	COG0583	DNA-binding transcription factor activity
FLP30_RS11180	COG1028	Short-chain dehydrogenase reductase Sdr
FLP30_RS11220	COG3052	prosthetic group binding
FLP30_RS11230	COG0583	DNA-binding transcription factor activity
FLP30_RS11260	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FLP30_RS11275	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FLP30_RS11335	COG2875	Belongs to the precorrin methyltransferase family
FLP30_RS11350	COG2099	Precorrin-6x reductase
FLP30_RS11395	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FLP30_RS11400	COG4191	Histidine kinase
FLP30_RS11400	COG0784	Response regulator, receiver
FLP30_RS11410	COG0784	Response regulator, receiver
FLP30_RS11460	COG0625	glutathione transferase activity
FLP30_RS11470	COG1797	cobyrinic acid a,c-diamide synthase activity
FLP30_RS11480	COG1492	cobalamin metabolic process
FLP30_RS11490	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FLP30_RS11495	COG2095	MarC family integral membrane protein
FLP30_RS11500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FLP30_RS11505	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FLP30_RS11515	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FLP30_RS11530	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS11535	COG0488	(ABC) transporter
FLP30_RS11540	COG0784	Response regulator, receiver
FLP30_RS11565	COG4988	ABC transporter
FLP30_RS11570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FLP30_RS11590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FLP30_RS11595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLP30_RS11600	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FLP30_RS11605	COG0456	acetyltransferase
FLP30_RS11610	COG1028	Short-chain dehydrogenase reductase Sdr
FLP30_RS11620	COG0242	peptide deformylase activity
FLP30_RS11625	COG2226	methyltransferase
FLP30_RS11635	COG1012	belongs to the aldehyde dehydrogenase family
FLP30_RS11640	COG2207	Transcriptional regulator
FLP30_RS11650	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FLP30_RS11665	COG0525	valine-tRNA ligase activity
FLP30_RS11670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLP30_RS11675	COG1116	anion transmembrane transporter activity
FLP30_RS11675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLP30_RS11685	COG0756	dUTP diphosphatase activity
FLP30_RS11690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLP30_RS11695	COG2226	methyltransferase
FLP30_RS11700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FLP30_RS11705	COG0268	Binds directly to 16S ribosomal RNA
FLP30_RS11710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FLP30_RS11720	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLP30_RS11730	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FLP30_RS11735	COG0504	CTP synthase activity
FLP30_RS11745	COG0149	triose-phosphate isomerase activity
FLP30_RS11755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLP30_RS11765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FLP30_RS11770	COG0134	indole-3-glycerol-phosphate synthase activity
FLP30_RS11775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLP30_RS11780	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLP30_RS11780	COG0022	dehydrogenase e1 component
FLP30_RS11785	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLP30_RS11790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLP30_RS11795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FLP30_RS11815	COG0741	lytic transglycosylase activity
FLP30_RS11820	COG0861	Integral membrane protein TerC family
FLP30_RS11825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLP30_RS11830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FLP30_RS11835	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLP30_RS11845	COG0047	phosphoribosylformylglycinamidine synthase activity
FLP30_RS11850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLP30_RS11860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FLP30_RS11870	COG0792	nuclease activity
FLP30_RS11875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLP30_RS11885	COG0628	permease
FLP30_RS11890	COG2897	thiosulfate sulfurtransferase activity
FLP30_RS11895	COG0626	cystathionine gamma-synthase activity
FLP30_RS11900	COG0606	chelatase, subunit chli
FLP30_RS11905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLP30_RS11915	COG3474	cytochrome
FLP30_RS11920	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FLP30_RS11925	COG0077	Prephenate dehydratase
FLP30_RS11925	COG1605	Chorismate mutase
FLP30_RS11930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLP30_RS11935	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FLP30_RS11940	COG1278	Cold shock
FLP30_RS11965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLP30_RS11975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLP30_RS11980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLP30_RS11985	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FLP30_RS12005	COG1663	tetraacyldisaccharide 4'-kinase activity
FLP30_RS12010	COG1519	Transferase
FLP30_RS12020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FLP30_RS12030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FLP30_RS12035	COG4208	sulfate ABC transporter
FLP30_RS12040	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FLP30_RS12055	COG0175	sulfate reduction
FLP30_RS12060	COG3042	response to heat
FLP30_RS12065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FLP30_RS12070	COG0602	queuosine metabolic process
FLP30_RS12075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FLP30_RS12090	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FLP30_RS12095	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FLP30_RS12100	COG0259	pyridoxamine-phosphate oxidase activity
FLP30_RS12115	COG0084	hydrolase, TatD family'
FLP30_RS12130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FLP30_RS12135	COG1686	Belongs to the peptidase S11 family
FLP30_RS12145	COG2951	lytic endotransglycosylase activity
FLP30_RS12150	COG0586	Pfam SNARE associated Golgi protein
FLP30_RS12160	COG1968	undecaprenyl-diphosphatase activity
FLP30_RS12180	COG2890	protein-(glutamine-N5) methyltransferase activity
FLP30_RS12190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FLP30_RS12195	COG0124	histidyl-tRNA synthetase
FLP30_RS12200	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FLP30_RS12210	COG2070	2-Nitropropane dioxygenase
FLP30_RS12215	COG0527	aspartate kinase activity
FLP30_RS12220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FLP30_RS12235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FLP30_RS12240	COG1040	competence protein
FLP30_RS12265	COG0321	lipoyl(octanoyl) transferase activity
FLP30_RS12280	COG0484	heat shock protein binding
FLP30_RS12310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FLP30_RS12315	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FLP30_RS12330	COG2022	thiamine diphosphate biosynthetic process
FLP30_RS12350	COG0148	phosphopyruvate hydratase activity
FLP30_RS12360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FLP30_RS12365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FLP30_RS12370	COG4106	trans-aconitate 2-methyltransferase activity
FLP30_RS12370	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FLP30_RS12380	COG0156	8-amino-7-oxononanoate synthase activity
FLP30_RS12385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLP30_RS12400	COG0322	excinuclease ABC activity
FLP30_RS12420	COG0729	surface antigen
FLP30_RS12430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLP30_RS12440	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FLP30_RS12450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLP30_RS12470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FLP30_RS12475	COG0287	Prephenate dehydrogenase
FLP30_RS12475	COG1605	Chorismate mutase
FLP30_RS12495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FLP30_RS12500	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FLP30_RS12505	COG0142	geranyltranstransferase activity
FLP30_RS12530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLP30_RS12545	COG1970	mechanosensitive ion channel activity
FLP30_RS12550	COG0254	rRNA binding
FLP30_RS12555	COG0071	Belongs to the small heat shock protein (HSP20) family
FLP30_RS12575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLP30_RS12580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLP30_RS12585	COG2003	Belongs to the UPF0758 family
FLP30_RS12590	COG2003	Belongs to the UPF0758 family
FLP30_RS12595	COG0210	DNA helicase
FLP30_RS12600	COG2264	protein methyltransferase activity
FLP30_RS12605	COG0006	proline dipeptidase activity
FLP30_RS12610	COG0473	3-isopropylmalate dehydrogenase activity
FLP30_RS12615	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FLP30_RS12620	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FLP30_RS12635	COG0114	fumarate hydratase activity
FLP30_RS12710	COG2805	Type II/IV secretion system protein
FLP30_RS12735	COG4957	zinc ion binding
FLP30_RS12755	COG4566	intracellular signal transduction
FLP30_RS12760	COG4191	Histidine kinase
FLP30_RS12785	COG0281	malic enzyme
FLP30_RS12830	COG0840	transmembrane signaling receptor activity
FLP30_RS12835	COG2161	toxin-antitoxin pair type II binding
FLP30_RS12840	COG4115	mRNA cleavage
FLP30_RS12860	COG3654	unkown
FLP30_RS12955	COG3437	response regulator, receiver
FLP30_RS12955	COG0784	Response regulator, receiver
FLP30_RS12985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FLP30_RS13020	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FLP30_RS13045	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FLP30_RS13115	COG4974	Belongs to the 'phage' integrase family
FLP30_RS13135	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FLP30_RS13140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FLP30_RS13150	COG1715	Restriction endonuclease
FLP30_RS13180	COG1733	regulation of RNA biosynthetic process
FLP30_RS13220	COG4221	oxidoreductase activity
FLP30_RS13225	COG0583	DNA-binding transcription factor activity
FLP30_RS13235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLP30_RS13305	COG2336	PFAM SpoVT AbrB
FLP30_RS13310	COG2337	Toxic component of a toxin-antitoxin (TA) module
FLP30_RS13380	COG1278	Cold shock
FLP30_RS13485	COG2161	toxin-antitoxin pair type II binding
FLP30_RS13505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FLP30_RS13530	COG4372	Transposase
FLP30_RS13535	COG3436	PFAM IS66 Orf2 family protein
FLP30_RS13575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLP30_RS13585	COG1160	GTP binding
FLP30_RS13595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLP30_RS13655	COG4227	nucleotidyltransferase activity
FLP30_RS13715	COG3831	ATPase activity
FLP30_RS13725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLP30_RS13735	COG0583	DNA-binding transcription factor activity
FLP30_RS13740	COG4221	oxidoreductase activity
FLP30_RS13755	COG1959	2 iron, 2 sulfur cluster binding
FLP30_RS13780	COG1733	regulation of RNA biosynthetic process
FLP30_RS13790	COG1335	isochorismatase
FLP30_RS13795	COG0477	Major facilitator Superfamily
FLP30_RS13810	COG0583	DNA-binding transcription factor activity
FLP30_RS13815	COG2814	Major facilitator Superfamily
FLP30_RS13860	COG0071	Belongs to the small heat shock protein (HSP20) family
FLP30_RS13925	COG1475	DNA binding
FLP30_RS13930	COG4774	siderophore transport
FLP30_RS13940	COG1192	Involved in chromosome partitioning
FLP30_RS13945	COG1475	DNA binding
FLP30_RS13955	COG2026	Addiction module toxin, RelE StbE family
FLP30_RS14005	COG0840	transmembrane signaling receptor activity
FLP30_RS14005	COG2972	Histidine kinase
FLP30_RS14025	COG2805	Type II/IV secretion system protein