locus-tag	class	description
WG31_RS00005	COG0424	maF-like protein
WG31_RS00020	COG1671	Belongs to the UPF0178 family
WG31_RS00030	COG2814	Major facilitator Superfamily
WG31_RS00040	COG2835	tetraacyldisaccharide 4'-kinase activity
WG31_RS00045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WG31_RS00055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WG31_RS00080	COG0778	Nitroreductase
WG31_RS00090	COG0456	acetyltransferase
WG31_RS00100	COG1570	exodeoxyribonuclease VII activity
WG31_RS00115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WG31_RS00120	COG1012	belongs to the aldehyde dehydrogenase family
WG31_RS00130	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WG31_RS00145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WG31_RS00155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WG31_RS00160	COG1053	succinate dehydrogenase
WG31_RS00165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WG31_RS00180	COG0126	phosphoglycerate kinase activity
WG31_RS00190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WG31_RS00200	COG0156	8-amino-7-oxononanoate synthase activity
WG31_RS00210	COG0405	Gamma-glutamyltransferase
WG31_RS00230	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
WG31_RS00240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WG31_RS00265	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WG31_RS00270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WG31_RS00280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WG31_RS00290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WG31_RS00295	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WG31_RS00300	COG0539	negative regulation of cytoplasmic translation
WG31_RS00310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WG31_RS00315	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WG31_RS00320	COG1420	regulation of RNA biosynthetic process
WG31_RS00325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WG31_RS00360	COG0772	Belongs to the SEDS family
WG31_RS00365	COG0768	penicillin binding
WG31_RS00385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WG31_RS00390	COG1612	heme a metabolic process
WG31_RS00400	COG2814	Major facilitator Superfamily
WG31_RS00410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WG31_RS00415	COG1289	transmembrane transporter activity
WG31_RS00425	COG1573	uracil-dna glycosylase
WG31_RS00445	COG0670	Belongs to the BI1 family
WG31_RS00470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WG31_RS00485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WG31_RS00500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WG31_RS00520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WG31_RS00540	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_RS00545	COG0586	Pfam SNARE associated Golgi protein
WG31_RS00555	COG0281	malic enzyme
WG31_RS00580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WG31_RS00585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WG31_RS00590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WG31_RS00595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WG31_RS00600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WG31_RS00605	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WG31_RS00610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WG31_RS00615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WG31_RS00630	COG1113	amino acid transport
WG31_RS00635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WG31_RS00640	COG4208	sulfate ABC transporter
WG31_RS00660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WG31_RS00665	COG2207	Transcriptional regulator
WG31_RS00670	COG4303	Ethanolamine ammonia lyase large subunit
WG31_RS00675	COG4302	ethanolamine ammonia-lyase activity
WG31_RS00680	COG1113	amino acid transport
WG31_RS00685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG31_RS00700	COG1278	Cold shock
WG31_RS00730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WG31_RS00735	COG0745	RESPONSE REGULATOR receiver
WG31_RS00740	COG0784	Response regulator, receiver
WG31_RS00740	COG2205	protein histidine kinase activity
WG31_RS00765	COG3842	ATPase activity
WG31_RS00805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WG31_RS00860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WG31_RS00865	COG4372	Transposase
WG31_RS00875	COG2963	transposase activity
WG31_RS00880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WG31_RS00955	COG2983	Belongs to the UPF0260 family
WG31_RS00995	COG1566	PFAM secretion protein HlyD family protein
WG31_RS01015	COG1657	PFAM Prenyltransferase squalene oxidase
WG31_RS01020	COG1233	COG1233 Phytoene dehydrogenase and related
WG31_RS01025	COG1562	ergosterol biosynthetic process
WG31_RS01030	COG1562	ergosterol biosynthetic process
WG31_RS01035	COG1215	transferase activity, transferring glycosyl groups
WG31_RS01040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WG31_RS01050	COG0287	Prephenate dehydrogenase
WG31_RS01065	COG0450	alkyl hydroperoxide reductase
WG31_RS01070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WG31_RS01080	COG2353	YceI-like domain
WG31_RS01090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WG31_RS01100	COG0488	(ABC) transporter
WG31_RS01120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WG31_RS01130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WG31_RS01135	COG0343	queuine tRNA-ribosyltransferase activity
WG31_RS01140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WG31_RS01150	COG1881	PFAM PEBP family protein
WG31_RS01165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WG31_RS01180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WG31_RS01210	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WG31_RS01215	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WG31_RS01230	COG0667	Aldo Keto reductase
WG31_RS01240	COG0556	nucleotide-excision repair
WG31_RS01250	COG0612	Peptidase, M16
WG31_RS01270	COG0463	Glycosyl transferase, family 2
WG31_RS01285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WG31_RS01295	COG0167	dihydroorotate dehydrogenase activity
WG31_RS01310	COG1692	metallophosphoesterase
WG31_RS01315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WG31_RS01345	COG0352	thiamine-phosphate diphosphorylase activity
WG31_RS01370	COG1509	lysine 2,3-aminomutase activity
WG31_RS01380	COG0024	Methionine aminopeptidase
WG31_RS01385	COG1686	Belongs to the peptidase S11 family
WG31_RS01390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WG31_RS01405	COG2326	polyphosphate kinase activity
WG31_RS01410	COG1678	Uncharacterized ACR, COG1678
WG31_RS01415	COG1660	Displays ATPase and GTPase activities
WG31_RS01425	COG2205	protein histidine kinase activity
WG31_RS01430	COG0745	RESPONSE REGULATOR receiver
WG31_RS01435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WG31_RS01440	COG0443	Heat shock 70 kDa protein
WG31_RS01445	COG0484	heat shock protein binding
WG31_RS01450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WG31_RS01455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WG31_RS01460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WG31_RS01465	COG0138	bifunctional purine biosynthesis protein purh
WG31_RS01475	COG0697	spore germination
WG31_RS01485	COG0752	glycyl-tRNA synthetase alpha subunit
WG31_RS01495	COG1396	sequence-specific DNA binding
WG31_RS01500	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WG31_RS01520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WG31_RS01530	COG0598	Magnesium transport protein CorA
WG31_RS01535	COG0133	tryptophan synthase activity
WG31_RS01540	COG0159	tryptophan synthase activity
WG31_RS01545	COG0493	'glutamate synthase
WG31_RS01555	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
WG31_RS01560	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WG31_RS01565	COG0745	RESPONSE REGULATOR receiver
WG31_RS01575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WG31_RS01600	COG1253	flavin adenine dinucleotide binding
WG31_RS01605	COG0604	alcohol dehydrogenase
WG31_RS01615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG31_RS01630	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_RS01635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WG31_RS01640	COG3956	TIGRFAM MazG family protein
WG31_RS01650	COG0326	Molecular chaperone. Has ATPase activity
WG31_RS01775	COG0629	single-stranded DNA binding
WG31_RS01865	COG1783	phage Terminase large subunit
WG31_RS02095	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WG31_RS02120	COG0318	PFAM AMP-dependent synthetase and ligase
WG31_RS02125	COG3321	synthase
WG31_RS02125	COG0604	alcohol dehydrogenase
WG31_RS02125	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_RS02130	COG0318	PFAM AMP-dependent synthetase and ligase
WG31_RS02140	COG4372	Transposase
WG31_RS02150	COG2963	transposase activity
WG31_RS02155	COG2223	nitrite transmembrane transporter activity
WG31_RS02240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WG31_RS02240	COG2755	lipolytic protein G-D-S-L family
WG31_RS02265	COG1396	sequence-specific DNA binding
WG31_RS02265	COG3800	Transcriptional regulator
WG31_RS02270	COG2079	MmgE PrpD family protein
WG31_RS02275	COG0372	Belongs to the citrate synthase family
WG31_RS02280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WG31_RS02285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WG31_RS02290	COG2814	Major facilitator Superfamily
WG31_RS02295	COG2319	Wd-40 repeat
WG31_RS02305	COG2309	aminopeptidase activity
WG31_RS02320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WG31_RS02330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WG31_RS02335	COG0193	aminoacyl-tRNA hydrolase activity
WG31_RS02340	COG0012	GTP binding
WG31_RS02345	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WG31_RS02350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WG31_RS02355	COG0799	negative regulation of ribosome biogenesis
WG31_RS02360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WG31_RS02395	COG0247	lactate metabolic process
WG31_RS02400	COG1139	Iron-sulfur cluster binding protein
WG31_RS02410	COG0697	spore germination
WG31_RS02415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WG31_RS02420	COG0717	Belongs to the dCTP deaminase family
WG31_RS02435	COG3394	polysaccharide catabolic process
WG31_RS02455	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WG31_RS02465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WG31_RS02470	COG1253	flavin adenine dinucleotide binding
WG31_RS02475	COG0741	lytic transglycosylase activity
WG31_RS02480	COG1573	uracil-dna glycosylase
WG31_RS02490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WG31_RS02530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WG31_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_RS02575	COG0583	DNA-binding transcription factor activity
WG31_RS02580	COG0025	NhaP-type Na H and K H
WG31_RS02585	COG4771	TonB-dependent receptor
WG31_RS02595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WG31_RS02600	COG1120	ATPase activity
WG31_RS02605	COG3525	Glycosyl hydrolase, family 20, catalytic domain
WG31_RS02610	COG2971	BadF BadG BcrA BcrD
WG31_RS02615	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
WG31_RS02635	COG0415	Belongs to the DNA photolyase family
WG31_RS02640	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WG31_RS02670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WG31_RS02755	COG1012	belongs to the aldehyde dehydrogenase family
WG31_RS02925	COG1802	Transcriptional regulator
WG31_RS02925	COG4626	Terminase
WG31_RS02955	COG0305	Participates in initiation and elongation during chromosome replication
WG31_RS03125	COG4774	siderophore transport
WG31_RS03240	COG1054	Belongs to the UPF0176 family
WG31_RS03395	COG1959	2 iron, 2 sulfur cluster binding
WG31_RS03400	COG4221	oxidoreductase activity
WG31_RS03405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WG31_RS03425	COG1607	acyl-coa hydrolase
WG31_RS03465	COG0306	phosphate transporter
WG31_RS03475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WG31_RS03480	COG0022	dehydrogenase e1 component
WG31_RS03490	COG0071	Belongs to the small heat shock protein (HSP20) family
WG31_RS03495	COG1252	NADH dehydrogenase
WG31_RS03505	COG0523	cobalamin synthesis protein
WG31_RS03515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WG31_RS03530	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
WG31_RS03535	COG0596	Alpha beta hydrolase
WG31_RS03550	COG1297	OPT oligopeptide transporter protein
WG31_RS03585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WG31_RS03595	COG0469	pyruvate kinase activity
WG31_RS03615	COG1217	gtp-binding protein TYPA
WG31_RS03625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG31_RS03630	COG0492	ferredoxin-NADP+ reductase activity
WG31_RS03635	COG0538	isocitrate dehydrogenase activity
WG31_RS03670	COG4993	Dehydrogenase
WG31_RS03685	COG0481	GTPase activity
WG31_RS03690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WG31_RS03695	COG2813	Specifically methylates the guanine in position
WG31_RS03695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WG31_RS03700	COG0513	Belongs to the DEAD box helicase family
WG31_RS03725	COG1758	RNA polymerase activity
WG31_RS03730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WG31_RS03735	COG0736	holo-[acyl-carrier-protein] synthase activity
WG31_RS03740	COG0681	Belongs to the peptidase S26 family
WG31_RS03745	COG0571	ribonuclease III activity
WG31_RS03750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WG31_RS03755	COG0528	UMP kinase activity
WG31_RS03760	COG0233	cytoplasmic translational termination
WG31_RS03765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WG31_RS03775	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WG31_RS03780	COG0750	zinc metalloprotease
WG31_RS03795	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WG31_RS03800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WG31_RS03805	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WG31_RS03810	COG3494	Protein of unknown function (DUF1009)
WG31_RS03815	COG0346	lactoylglutathione lyase activity
WG31_RS03825	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WG31_RS03830	COG0594	ribonuclease P activity
WG31_RS03835	COG0706	membrane insertase activity
WG31_RS03840	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WG31_RS03845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WG31_RS03850	COG2171	N-acyltransferase activity
WG31_RS03855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WG31_RS03865	COG0101	tRNA pseudouridine synthase activity
WG31_RS03870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WG31_RS03875	COG0242	peptide deformylase activity
WG31_RS03890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WG31_RS03905	COG0633	Ferredoxin
WG31_RS03905	COG3217	Mosc domain protein beta barrel domain protein
WG31_RS03910	COG1137	ATPase activity
WG31_RS03925	COG0517	IMP dehydrogenase activity
WG31_RS03925	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WG31_RS03935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WG31_RS03940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WG31_RS03945	COG4221	oxidoreductase activity
WG31_RS03950	COG0194	GDP metabolic process
WG31_RS03955	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WG31_RS03955	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WG31_RS03960	COG2942	2-epimerase
WG31_RS03965	COG0305	Participates in initiation and elongation during chromosome replication
WG31_RS03970	COG1196	nuclear chromosome segregation
WG31_RS03970	COG3264	Mechanosensitive ion channel
WG31_RS03975	COG1127	ABC transporter
WG31_RS03980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WG31_RS04010	COG1113	amino acid transport
WG31_RS04020	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WG31_RS04020	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WG31_RS04020	COG0506	proline dehydrogenase activity
WG31_RS04035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WG31_RS04065	COG2096	Adenosyltransferase
WG31_RS04080	COG0277	FAD linked oxidase domain protein
WG31_RS04090	COG0009	L-threonylcarbamoyladenylate synthase
WG31_RS04100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WG31_RS04110	COG0656	L-ascorbic acid biosynthetic process
WG31_RS04120	COG1643	Atp-dependent helicase
WG31_RS04140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WG31_RS04145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WG31_RS04165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WG31_RS04170	COG0235	Class ii aldolase
WG31_RS04175	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
WG31_RS04180	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
WG31_RS04185	COG0196	riboflavin kinase activity
WG31_RS04190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WG31_RS04195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WG31_RS04205	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WG31_RS04215	COG5006	permease, DMT superfamily
WG31_RS04220	COG0187	DNA topoisomerase II activity
WG31_RS04235	COG1959	2 iron, 2 sulfur cluster binding
WG31_RS04240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WG31_RS04245	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WG31_RS04245	COG2885	chlorophyll binding
WG31_RS04255	COG0793	Belongs to the peptidase S41A family
WG31_RS04260	COG0557	exoribonuclease II activity
WG31_RS04265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WG31_RS04270	COG0758	DNA mediated transformation
WG31_RS04275	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WG31_RS04280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WG31_RS04285	COG0540	Belongs to the ATCase OTCase family
WG31_RS04290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WG31_RS04295	COG2333	competence protein COMEC
WG31_RS04295	COG0658	competence protein
WG31_RS04300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WG31_RS04305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WG31_RS04315	COG0508	dehydrogenase complex catalyzes the overall conversion of
WG31_RS04335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WG31_RS04350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WG31_RS04385	COG3260	NADH ubiquinone oxidoreductase 20
WG31_RS04390	COG1183	phosphatidylcholine synthase activity
WG31_RS04395	COG0688	phosphatidylethanolamine metabolic process
WG31_RS04400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WG31_RS04410	COG2885	chlorophyll binding
WG31_RS04410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WG31_RS04415	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WG31_RS04425	COG4974	Belongs to the 'phage' integrase family
WG31_RS04430	COG0825	malonyl-CoA metabolic process
WG31_RS04435	COG1058	Belongs to the CinA family
WG31_RS04435	COG1546	Belongs to the CinA family
WG31_RS04455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WG31_RS04460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WG31_RS04465	COG0181	hydroxymethylbilane synthase activity
WG31_RS04475	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WG31_RS04480	COG0406	alpha-ribazole phosphatase activity
WG31_RS04490	COG2189	Belongs to the N(4) N(6)-methyltransferase family
WG31_RS04510	COG0408	coproporphyrinogen oxidase activity
WG31_RS04515	COG2857	Cytochrome c1
WG31_RS04515	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WG31_RS04520	COG2857	Cytochrome c1
WG31_RS04520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WG31_RS04525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
WG31_RS04545	COG0778	Nitroreductase
WG31_RS04625	COG1518	maintenance of DNA repeat elements
WG31_RS04805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WG31_RS04810	COG1902	pentaerythritol trinitrate reductase activity
WG31_RS04815	COG0640	Transcriptional regulator
WG31_RS04825	COG3591	Belongs to the peptidase S1B family
WG31_RS04830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WG31_RS04840	COG0019	diaminopimelate decarboxylase activity
WG31_RS04845	COG0165	Argininosuccinate lyase
WG31_RS04865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WG31_RS04870	COG0237	dephospho-CoA kinase activity
WG31_RS04875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WG31_RS04895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WG31_RS04905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WG31_RS04910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WG31_RS04920	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WG31_RS04925	COG0248	Ppx GppA phosphatase
WG31_RS04940	COG1121	(ABC) transporter
WG31_RS04965	COG1289	transmembrane transporter activity
WG31_RS04970	COG1289	transmembrane transporter activity
WG31_RS04990	COG3088	subunit of a heme lyase
WG31_RS04995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WG31_RS05000	COG1138	Cytochrome C-type biogenesis protein
WG31_RS05005	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
WG31_RS05010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WG31_RS05045	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WG31_RS05075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WG31_RS05085	COG0477	Major facilitator Superfamily
WG31_RS05090	COG1322	Protein conserved in bacteria
WG31_RS05120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WG31_RS05125	COG0081	regulation of translation
WG31_RS05130	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WG31_RS05135	COG0222	ribosome binding
WG31_RS05145	COG0085	RNA polymerase activity
WG31_RS05150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WG31_RS05155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WG31_RS05160	COG0049	tRNA binding
WG31_RS05165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WG31_RS05170	COG0051	transcription antitermination factor activity, RNA binding
WG31_RS05175	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WG31_RS05180	COG0088	Forms part of the polypeptide exit tunnel
WG31_RS05185	COG0089	rRNA binding
WG31_RS05190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WG31_RS05195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WG31_RS05200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WG31_RS05205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WG31_RS05210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WG31_RS05215	COG0255	Belongs to the universal ribosomal protein uL29 family
WG31_RS05220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WG31_RS05225	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WG31_RS05230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WG31_RS05235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WG31_RS05240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WG31_RS05245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WG31_RS05250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WG31_RS05255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WG31_RS05260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WG31_RS05265	COG1841	ribosomal large subunit assembly
WG31_RS05270	COG0200	Binds to the 23S rRNA
WG31_RS05280	COG0563	adenylate kinase activity
WG31_RS05285	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WG31_RS05290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WG31_RS05295	COG0202	RNA polymerase activity
WG31_RS05300	COG0203	ribosomal protein L17
WG31_RS05310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG31_RS05315	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WG31_RS05340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG31_RS05350	COG3237	CsbD-like
WG31_RS05355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WG31_RS05360	COG2189	Belongs to the N(4) N(6)-methyltransferase family
WG31_RS05385	COG0714	Associated with various cellular activities
WG31_RS05395	COG0617	tRNA 3'-terminal CCA addition
WG31_RS05400	COG1132	(ABC) transporter
WG31_RS05410	COG2814	Major facilitator Superfamily
WG31_RS05415	COG1051	belongs to the nudix hydrolase family
WG31_RS05425	COG0793	Belongs to the peptidase S41A family
WG31_RS05440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WG31_RS05445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WG31_RS05450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WG31_RS05455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WG31_RS05460	COG0505	Belongs to the CarA family
WG31_RS05470	COG0358	DNA primase activity
WG31_RS05475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WG31_RS05485	COG0360	Binds together with S18 to 16S ribosomal RNA
WG31_RS05490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WG31_RS05495	COG0359	binds to the 23S rRNA
WG31_RS05500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WG31_RS05505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WG31_RS05535	COG1132	(ABC) transporter
WG31_RS05540	COG1802	Transcriptional regulator
WG31_RS05545	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WG31_RS05555	COG0850	regulation of cytokinetic process
WG31_RS05565	COG2081	HI0933 family
WG31_RS05570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WG31_RS05580	COG0457	Tetratricopeptide repeat
WG31_RS05580	COG0859	PFAM glycosyl transferase family 9
WG31_RS05590	COG3781	membrane
WG31_RS05595	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WG31_RS05610	COG2884	Cell division ATP-binding protein ftsE
WG31_RS05635	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WG31_RS05640	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WG31_RS05645	COG2166	iron-sulfur cluster assembly
WG31_RS05660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WG31_RS05660	COG2010	Cytochrome c
WG31_RS05665	COG0246	Mannitol dehydrogenase
WG31_RS05670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WG31_RS05675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WG31_RS05680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WG31_RS05685	COG0072	phenylalanine-tRNA ligase activity
WG31_RS05685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WG31_RS05690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WG31_RS05695	COG0747	negative chemotaxis
WG31_RS05715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WG31_RS05730	COG0473	3-isopropylmalate dehydrogenase activity
WG31_RS05735	COG0006	proline dipeptidase activity
WG31_RS05740	COG2264	protein methyltransferase activity
WG31_RS05745	COG0210	DNA helicase
WG31_RS05750	COG2003	Belongs to the UPF0758 family
WG31_RS05755	COG2003	Belongs to the UPF0758 family
WG31_RS05760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WG31_RS05785	COG0071	Belongs to the small heat shock protein (HSP20) family
WG31_RS05790	COG0254	rRNA binding
WG31_RS05795	COG1970	mechanosensitive ion channel activity
WG31_RS05805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WG31_RS05810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WG31_RS05820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WG31_RS05820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WG31_RS05825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WG31_RS05835	COG0142	geranyltranstransferase activity
WG31_RS05840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WG31_RS05845	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WG31_RS05860	COG2062	phosphohistidine phosphatase, SixA
WG31_RS05865	COG1605	Chorismate mutase
WG31_RS05865	COG0287	Prephenate dehydrogenase
WG31_RS05895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WG31_RS05905	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WG31_RS05915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WG31_RS05925	COG0729	surface antigen
WG31_RS05945	COG0322	excinuclease ABC activity
WG31_RS05960	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WG31_RS05965	COG0314	molybdopterin synthase activity
WG31_RS05970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WG31_RS05975	COG0156	8-amino-7-oxononanoate synthase activity
WG31_RS05985	COG4106	trans-aconitate 2-methyltransferase activity
WG31_RS05985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WG31_RS05990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WG31_RS05995	COG0303	'Molybdopterin
WG31_RS06000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WG31_RS06010	COG0148	phosphopyruvate hydratase activity
WG31_RS06030	COG2022	thiamine diphosphate biosynthetic process
WG31_RS06045	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WG31_RS06050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WG31_RS06060	COG0385	Bile acid
WG31_RS06065	COG0076	glutamate decarboxylase activity
WG31_RS06080	COG0484	heat shock protein binding
WG31_RS06085	COG0271	Belongs to the BolA IbaG family
WG31_RS06095	COG0321	lipoyl(octanoyl) transferase activity
WG31_RS06115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WG31_RS06120	COG2226	methyltransferase
WG31_RS06145	COG2706	6-phosphogluconolactonase activity
WG31_RS06150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WG31_RS06155	COG0527	aspartate kinase activity
WG31_RS06160	COG2070	2-Nitropropane dioxygenase
WG31_RS06170	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WG31_RS06175	COG0124	histidyl-tRNA synthetase
WG31_RS06180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WG31_RS06190	COG2890	protein-(glutamine-N5) methyltransferase activity
WG31_RS06210	COG1968	undecaprenyl-diphosphatase activity
WG31_RS06215	COG0531	amino acid
WG31_RS06230	COG2951	lytic endotransglycosylase activity
WG31_RS06235	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WG31_RS06240	COG1686	Belongs to the peptidase S11 family
WG31_RS06245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WG31_RS06260	COG0084	hydrolase, TatD family'
WG31_RS06275	COG0259	pyridoxamine-phosphate oxidase activity
WG31_RS06280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WG31_RS06285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WG31_RS06290	COG1764	response to oxidative stress
WG31_RS06295	COG0579	oxidoreductase
WG31_RS06305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WG31_RS06310	COG0602	queuosine metabolic process
WG31_RS06315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WG31_RS06325	COG0175	sulfate reduction
WG31_RS06330	COG0175	sulfate reduction
WG31_RS06345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WG31_RS06355	COG1519	Transferase
WG31_RS06360	COG1663	tetraacyldisaccharide 4'-kinase activity
WG31_RS06380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WG31_RS06385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WG31_RS06390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WG31_RS06400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WG31_RS06430	COG1278	Cold shock
WG31_RS06435	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WG31_RS06440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WG31_RS06445	COG0077	Prephenate dehydratase
WG31_RS06445	COG1605	Chorismate mutase
WG31_RS06450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WG31_RS06455	COG3474	cytochrome
WG31_RS06465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WG31_RS06470	COG0606	chelatase, subunit chli
WG31_RS06475	COG0626	cystathionine gamma-synthase activity
WG31_RS06480	COG2897	thiosulfate sulfurtransferase activity
WG31_RS06485	COG0628	permease
WG31_RS06495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WG31_RS06500	COG0792	nuclease activity
WG31_RS06510	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WG31_RS06515	COG0271	Belongs to the BolA IbaG family
WG31_RS06520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WG31_RS06525	COG0047	phosphoribosylformylglycinamidine synthase activity
WG31_RS06535	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WG31_RS06540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WG31_RS06545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WG31_RS06550	COG0861	Integral membrane protein TerC family
WG31_RS06565	COG1546	Belongs to the CinA family
WG31_RS06580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WG31_RS06585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WG31_RS06590	COG0508	dehydrogenase complex catalyzes the overall conversion of
WG31_RS06595	COG0508	dehydrogenase complex catalyzes the overall conversion of
WG31_RS06595	COG0022	dehydrogenase e1 component
WG31_RS06600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WG31_RS06605	COG0315	cyclic pyranopterin monophosphate synthase activity
WG31_RS06610	COG0134	indole-3-glycerol-phosphate synthase activity
WG31_RS06615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WG31_RS06625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WG31_RS06635	COG0149	triose-phosphate isomerase activity
WG31_RS06645	COG0504	CTP synthase activity
WG31_RS06650	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WG31_RS06660	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WG31_RS06670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WG31_RS06675	COG0268	Binds directly to 16S ribosomal RNA
WG31_RS06680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WG31_RS06685	COG2226	methyltransferase
WG31_RS06690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WG31_RS06695	COG0756	dUTP diphosphatase activity
WG31_RS06700	COG1176	ABC-type spermidine putrescine transport system, permease component I
WG31_RS06705	COG1116	anion transmembrane transporter activity
WG31_RS06710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WG31_RS06715	COG0525	valine-tRNA ligase activity
WG31_RS06730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WG31_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_RS06760	COG0456	acetyltransferase
WG31_RS06765	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
WG31_RS06770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WG31_RS06775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WG31_RS06785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WG31_RS06790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WG31_RS06800	COG1349	DNA-binding transcription factor activity
WG31_RS06815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WG31_RS06820	COG4988	ABC transporter
WG31_RS06845	COG0784	Response regulator, receiver
WG31_RS06850	COG0488	(ABC) transporter
WG31_RS06865	COG2824	Alkylphosphonate utilization operon protein PhnA
WG31_RS06870	COG0814	amino acid
WG31_RS06880	COG0384	phenazine biosynthesis protein PhzF
WG31_RS06920	COG4206	TonB-dependent receptor
WG31_RS06930	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WG31_RS06955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WG31_RS06965	COG2233	PERMEase
WG31_RS06970	COG2351	hydroxyisourate hydrolase activity
WG31_RS06985	COG2072	flavoprotein involved in K transport
WG31_RS06995	COG0402	S-adenosylhomocysteine deaminase activity
WG31_RS07030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG31_RS07035	COG0842	Transport permease protein
WG31_RS07035	COG1129	ABC transporter
WG31_RS07040	COG0842	Transport permease protein
WG31_RS07055	COG1657	PFAM Prenyltransferase squalene oxidase
WG31_RS07075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WG31_RS07080	COG0753	catalase activity
WG31_RS07095	COG3459	Glycosyltransferase 36 associated
WG31_RS07130	COG4178	(ABC) transporter
WG31_RS07190	COG0477	Major facilitator Superfamily
WG31_RS07205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG31_RS07210	COG1116	anion transmembrane transporter activity
WG31_RS07215	COG0864	Transcriptional regulator
WG31_RS07220	COG3665	Urea carboxylase-associated protein
WG31_RS07225	COG3665	Urea carboxylase-associated protein
WG31_RS07250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WG31_RS07260	COG1960	acyl-CoA dehydrogenase activity
WG31_RS07285	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
WG31_RS07290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WG31_RS07295	COG4558	Periplasmic binding protein
WG31_RS07300	COG1321	iron dependent repressor
WG31_RS07305	COG1914	H( )-stimulated, divalent metal cation uptake system
WG31_RS07320	COG0848	biopolymer transport protein
WG31_RS07340	COG4372	Transposase
WG31_RS07350	COG2963	transposase activity
WG31_RS07355	COG4774	siderophore transport
WG31_RS07370	COG4774	siderophore transport
WG31_RS07380	COG1191	sigma factor activity
WG31_RS07385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WG31_RS07390	COG1116	anion transmembrane transporter activity
WG31_RS07395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG31_RS07405	COG2175	clavaminate synthase activity
WG31_RS07485	COG2373	Large extracellular alpha-helical protein
WG31_RS07490	COG4953	penicillin-binding protein 1C
WG31_RS07535	COG4774	siderophore transport
WG31_RS07600	COG1301	dicarboxylic acid transport
WG31_RS07605	COG0500	methyltransferase
WG31_RS07610	COG2999	glutathione oxidoreductase activity
WG31_RS07615	COG2814	Major facilitator Superfamily
WG31_RS07620	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
WG31_RS07670	COG0114	fumarate hydratase activity
WG31_RS07720	COG0628	permease
WG31_RS07740	COG0167	dihydroorotate dehydrogenase activity
WG31_RS07745	COG0674	pyruvate-flavodoxin oxidoreductase activity
WG31_RS07745	COG1013	pyruvate-flavodoxin oxidoreductase activity
WG31_RS07745	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WG31_RS07745	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WG31_RS07750	COG0493	'glutamate synthase
WG31_RS07760	COG1971	Probably functions as a manganese efflux pump
WG31_RS07770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WG31_RS07775	COG0746	molybdenum cofactor guanylyltransferase activity
WG31_RS07780	COG1763	Mo-molybdopterin cofactor biosynthetic process
WG31_RS07785	COG0303	'Molybdopterin
WG31_RS07790	COG3058	Necessary for formate dehydrogenase activity
WG31_RS07795	COG2864	formate dehydrogenase
WG31_RS07800	COG0437	4 iron, 4 sulfur cluster binding
WG31_RS07805	COG0243	molybdopterin cofactor binding
WG31_RS07805	COG3383	formate dehydrogenase (NAD+) activity
WG31_RS07815	COG0248	Ppx GppA phosphatase
WG31_RS07820	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WG31_RS07825	COG1940	carbohydrate kinase activity
WG31_RS07830	COG0425	Belongs to the sulfur carrier protein TusA family
WG31_RS07835	COG1722	exodeoxyribonuclease VII activity
WG31_RS07840	COG0142	geranyltranstransferase activity
WG31_RS07845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WG31_RS07850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
WG31_RS07860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WG31_RS07865	COG0137	argininosuccinate synthase activity
WG31_RS07870	COG0545	Peptidyl-prolyl cis-trans isomerase
WG31_RS07880	COG0180	Tryptophanyl-tRNA synthetase
WG31_RS07895	COG0745	RESPONSE REGULATOR receiver
WG31_RS07910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WG31_RS07910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WG31_RS07920	COG0747	negative chemotaxis
WG31_RS07925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG31_RS07940	COG4608	Belongs to the ABC transporter superfamily
WG31_RS07945	COG2070	2-Nitropropane dioxygenase
WG31_RS07950	COG0671	phosphoesterase, PA-phosphatase related
WG31_RS07960	COG3511	phospholipase C
WG31_RS07975	COG1695	Transcriptional regulator
WG31_RS07985	COG1032	radical SAM domain protein
WG31_RS08000	COG0668	transmembrane transport
WG31_RS08015	COG1294	oxidase, subunit
WG31_RS08020	COG1271	oxidase subunit
WG31_RS08025	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WG31_RS08030	COG4988	ABC transporter
WG31_RS08035	COG3128	pkhd-type hydroxylase
WG31_RS08040	COG4774	siderophore transport
WG31_RS08055	COG0252	asparaginase activity
WG31_RS08065	COG2985	domain, Protein
WG31_RS08080	COG3293	Transposase
WG31_RS08085	COG0488	(ABC) transporter
WG31_RS08100	COG1064	alcohol dehydrogenase
WG31_RS08125	COG2814	Major facilitator Superfamily
WG31_RS08135	COG1902	pentaerythritol trinitrate reductase activity
WG31_RS08165	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WG31_RS08175	COG0583	DNA-binding transcription factor activity
WG31_RS08180	COG0789	Transcriptional regulator
WG31_RS08195	COG4221	oxidoreductase activity
WG31_RS08240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WG31_RS08280	COG0789	Transcriptional regulator
WG31_RS08325	COG0318	PFAM AMP-dependent synthetase and ligase
WG31_RS08335	COG0156	8-amino-7-oxononanoate synthase activity
WG31_RS08350	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WG31_RS08375	COG0546	phosphoglycolate phosphatase activity
WG31_RS08380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WG31_RS08385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WG31_RS08400	COG0386	Belongs to the glutathione peroxidase family
WG31_RS08405	COG1136	(ABC) transporter
WG31_RS08415	COG0442	prolyl-tRNA aminoacylation
WG31_RS08425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
WG31_RS08435	COG1007	ATP synthesis coupled electron transport
WG31_RS08445	COG0713	ATP synthesis coupled electron transport
WG31_RS08455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG31_RS08460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WG31_RS08465	COG1034	ATP synthesis coupled electron transport
WG31_RS08475	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WG31_RS08480	COG0649	NAD binding
WG31_RS08485	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG31_RS08490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG31_RS08505	COG0776	regulation of translation
WG31_RS08515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WG31_RS08520	COG0740	serine-type endopeptidase activity
WG31_RS08525	COG0544	peptidyl-prolyl cis-trans isomerase activity
WG31_RS08535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WG31_RS08535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WG31_RS08545	COG0513	Belongs to the DEAD box helicase family
WG31_RS08555	COG0316	Belongs to the HesB IscA family
WG31_RS08560	COG2151	metal-sulfur cluster biosynthetic enzyme
WG31_RS08570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WG31_RS08575	COG0719	Fe-S assembly protein
WG31_RS08580	COG0396	ATPase activity
WG31_RS08585	COG0719	Fe-S assembly protein
WG31_RS08595	COG2733	membrane
WG31_RS08600	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WG31_RS08610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WG31_RS08615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WG31_RS08625	COG5265	(ABC) transporter
WG31_RS08635	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WG31_RS08640	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WG31_RS08665	COG0612	Peptidase, M16
WG31_RS08670	COG0312	modulator of DNA gyrase
WG31_RS08685	COG0109	protoheme IX farnesyltransferase activity
WG31_RS08695	COG2226	methyltransferase
WG31_RS08715	COG0463	Glycosyl transferase, family 2
WG31_RS08720	COG1522	sequence-specific DNA binding
WG31_RS08725	COG0492	ferredoxin-NADP+ reductase activity
WG31_RS08730	COG0583	DNA-binding transcription factor activity
WG31_RS08735	COG4957	zinc ion binding
WG31_RS08740	COG0776	regulation of translation
WG31_RS08770	COG0776	regulation of translation
WG31_RS08775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WG31_RS08780	COG0416	fatty acid biosynthetic process
WG31_RS08785	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WG31_RS08805	COG0745	RESPONSE REGULATOR receiver
WG31_RS08810	COG1846	Transcriptional regulator
WG31_RS08820	COG0242	peptide deformylase activity
WG31_RS08825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WG31_RS08830	COG0473	3-isopropylmalate dehydrogenase activity
WG31_RS08835	COG0066	3-isopropylmalate dehydratase activity
WG31_RS08840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WG31_RS08845	COG0335	large ribosomal subunit rRNA binding
WG31_RS08850	COG0336	Belongs to the RNA methyltransferase TrmD family
WG31_RS08855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WG31_RS08860	COG0228	four-way junction DNA binding
WG31_RS08885	COG0564	pseudouridine synthase activity
WG31_RS08890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WG31_RS08900	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WG31_RS08910	COG3572	ergothioneine biosynthetic process
WG31_RS08915	COG2814	Major facilitator Superfamily
WG31_RS08920	COG1160	GTP binding
WG31_RS08945	COG0438	transferase activity, transferring glycosyl groups
WG31_RS08950	COG0367	asparagine synthase
WG31_RS08955	COG0354	folic acid binding
WG31_RS08960	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WG31_RS08965	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WG31_RS08970	COG0659	secondary active sulfate transmembrane transporter activity
WG31_RS08990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WG31_RS09000	COG1051	belongs to the nudix hydrolase family
WG31_RS09005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WG31_RS09010	COG1923	regulation of RNA biosynthetic process
WG31_RS09015	COG2204	response regulator
WG31_RS09040	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WG31_RS09040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WG31_RS09045	COG0463	Glycosyl transferase, family 2
WG31_RS09090	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WG31_RS09100	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WG31_RS09115	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WG31_RS09120	COG0347	Belongs to the P(II) protein family
WG31_RS09130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WG31_RS09135	COG0586	Pfam SNARE associated Golgi protein
WG31_RS09140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WG31_RS09260	COG4386	tail sheath protein
WG31_RS09300	COG0616	signal peptide processing
WG31_RS09340	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WG31_RS09465	COG0582	viral genome integration into host DNA
WG31_RS09475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WG31_RS09480	COG0483	inositol monophosphate 1-phosphatase activity
WG31_RS09485	COG1199	ATP-dependent helicase activity
WG31_RS09490	COG1278	Cold shock
WG31_RS09495	COG0412	Dienelactone hydrolase
WG31_RS09500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WG31_RS09505	COG0459	protein refolding
WG31_RS09560	COG0004	ammonium transporteR
WG31_RS09580	COG4974	Belongs to the 'phage' integrase family
WG31_RS09590	COG1862	Preprotein translocase
WG31_RS09605	COG0494	nUDIX hydrolase
WG31_RS09625	COG0302	gtp cyclohydrolase
WG31_RS09635	COG0521	Mo-molybdopterin cofactor biosynthetic process
WG31_RS09665	COG1566	PFAM secretion protein HlyD family protein
WG31_RS09695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WG31_RS09700	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WG31_RS09700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WG31_RS09705	COG0307	riboflavin synthase, alpha
WG31_RS09715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WG31_RS09715	COG2857	Cytochrome c1
WG31_RS09720	COG2857	Cytochrome c1
WG31_RS09720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WG31_RS09725	COG0723	plastoquinol--plastocyanin reductase activity
WG31_RS09745	COG2252	PERMEase
WG31_RS09805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WG31_RS09810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WG31_RS09815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WG31_RS09820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
WG31_RS09830	COG3750	Belongs to the UPF0335 family
WG31_RS09835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WG31_RS09845	COG0657	acetylesterase activity
WG31_RS09855	COG2001	Belongs to the MraZ family
WG31_RS09860	COG0275	rRNA processing
WG31_RS09875	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WG31_RS09885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WG31_RS09890	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WG31_RS09900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WG31_RS09905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WG31_RS09910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WG31_RS09915	COG1181	Belongs to the D-alanine--D-alanine ligase family
WG31_RS09920	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WG31_RS09925	COG0849	cell division
WG31_RS09935	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WG31_RS09940	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WG31_RS09945	COG0497	DNA recombination
WG31_RS09950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WG31_RS09955	COG0574	Belongs to the PEP-utilizing enzyme family
WG31_RS09955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WG31_RS09960	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WG31_RS09985	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
WG31_RS10000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WG31_RS10005	COG1335	isochorismatase
WG31_RS10025	COG2132	Multicopper oxidase
WG31_RS10035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WG31_RS10045	COG0028	Belongs to the TPP enzyme family
WG31_RS10050	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WG31_RS10055	COG0560	Phosphoserine phosphatase
WG31_RS10070	COG0513	Belongs to the DEAD box helicase family
WG31_RS10090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WG31_RS10095	COG0531	amino acid
WG31_RS10100	COG0113	porphobilinogen synthase activity
WG31_RS10105	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WG31_RS10110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WG31_RS10115	COG1381	Involved in DNA repair and RecF pathway recombination
WG31_RS10120	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WG31_RS10125	COG0052	Belongs to the universal ribosomal protein uS2 family
WG31_RS10145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WG31_RS10155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WG31_RS10160	COG0251	oxidation-reduction process
WG31_RS10175	COG0436	Aminotransferase
WG31_RS10180	COG0436	Aminotransferase
WG31_RS10185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WG31_RS10205	COG3161	chorismate lyase activity
WG31_RS10210	COG1032	radical SAM domain protein
WG31_RS10215	COG0105	UTP biosynthetic process
WG31_RS10220	COG0488	(ABC) transporter
WG31_RS10230	COG0745	RESPONSE REGULATOR receiver
WG31_RS10245	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WG31_RS10250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WG31_RS10285	COG0328	RNA-DNA hybrid ribonuclease activity
WG31_RS10290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WG31_RS10295	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WG31_RS10345	COG1530	ribonuclease E activity
WG31_RS10350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WG31_RS10355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WG31_RS10360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WG31_RS10365	COG0424	maF-like protein
WG31_RS10375	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WG31_RS10405	COG0277	FAD linked oxidase domain protein
WG31_RS10420	COG2308	Evidence 4 Homologs of previously reported genes of
WG31_RS10440	COG1309	transcriptional regulator
WG31_RS10445	COG1252	NADH dehydrogenase
WG31_RS10450	COG1012	belongs to the aldehyde dehydrogenase family
WG31_RS10455	COG2814	Major facilitator Superfamily
WG31_RS10465	COG0431	NADPH-dependent FMN reductase
WG31_RS10475	COG0583	DNA-binding transcription factor activity
WG31_RS10485	COG1999	signal sequence binding
WG31_RS10530	COG0436	Aminotransferase
WG31_RS10535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WG31_RS10540	COG0384	phenazine biosynthesis protein PhzF
WG31_RS10545	COG1309	transcriptional regulator
WG31_RS10550	COG4221	oxidoreductase activity
WG31_RS10560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WG31_RS10565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WG31_RS10590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WG31_RS10630	COG0583	DNA-binding transcription factor activity
WG31_RS10635	COG1289	transmembrane transporter activity
WG31_RS10660	COG4232	protein-disulfide reductase activity
WG31_RS10670	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WG31_RS10675	COG0805	protein transport
WG31_RS10680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WG31_RS10685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WG31_RS10690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WG31_RS10700	COG0018	arginyl-trna synthetase
WG31_RS10705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WG31_RS10710	COG0316	Belongs to the HesB IscA family
WG31_RS10715	COG0708	Exodeoxyribonuclease III
WG31_RS10735	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WG31_RS10740	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
WG31_RS10750	COG0535	radical SAM domain protein
WG31_RS10760	COG0740	serine-type endopeptidase activity
WG31_RS10770	COG0436	Aminotransferase
WG31_RS10780	COG1494	fructose-1,6-bisphosphatase
WG31_RS10795	COG0564	pseudouridine synthase activity
WG31_RS10800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WG31_RS10805	COG1120	ATPase activity
WG31_RS10810	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WG31_RS10815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WG31_RS10820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WG31_RS10820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WG31_RS10845	COG1294	oxidase, subunit
WG31_RS10850	COG1271	oxidase subunit
WG31_RS10870	COG1113	amino acid transport
WG31_RS10890	COG0135	phosphoribosylanthranilate isomerase activity
WG31_RS10895	COG0284	orotidine-5'-phosphate decarboxylase activity
WG31_RS10905	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WG31_RS10915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WG31_RS10920	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WG31_RS10930	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WG31_RS10955	COG3145	DNA-N1-methyladenine dioxygenase activity
WG31_RS10965	COG3620	sequence-specific DNA binding
WG31_RS10975	COG2011	ABC-type metal ion transport system permease component
WG31_RS10980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WG31_RS10990	COG0277	FAD linked oxidase domain protein
WG31_RS10995	COG1648	precorrin-2 dehydrogenase activity
WG31_RS10995	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WG31_RS11015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WG31_RS11020	COG0477	Major facilitator Superfamily
WG31_RS11025	COG1335	isochorismatase
WG31_RS11040	COG0071	Belongs to the small heat shock protein (HSP20) family
WG31_RS11085	COG1522	sequence-specific DNA binding
WG31_RS11090	COG2515	1-aminocyclopropane-1-carboxylate deaminase
WG31_RS11095	COG1522	sequence-specific DNA binding
WG31_RS11200	COG4372	Transposase
WG31_RS11225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WG31_RS11275	COG0848	biopolymer transport protein
WG31_RS11295	COG1301	dicarboxylic acid transport
WG31_RS11330	COG2814	Major facilitator Superfamily
WG31_RS11340	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
WG31_RS11345	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
WG31_RS11360	COG0778	Nitroreductase
WG31_RS11365	COG1492	cobalamin metabolic process
WG31_RS11380	COG1797	cobyrinic acid a,c-diamide synthase activity
WG31_RS11405	COG1289	transmembrane transporter activity
WG31_RS11410	COG1584	GPR1 FUN34 yaaH family protein
WG31_RS11415	COG1024	Enoyl-CoA hydratase
WG31_RS11420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WG31_RS11425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WG31_RS11440	COG0735	belongs to the Fur family
WG31_RS11455	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
WG31_RS11475	COG0519	Catalyzes the synthesis of GMP from XMP
WG31_RS11475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WG31_RS11490	COG2814	Major facilitator Superfamily
WG31_RS11495	COG0739	heme binding
WG31_RS11495	COG0741	lytic transglycosylase activity
WG31_RS11495	COG1196	nuclear chromosome segregation
WG31_RS11515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WG31_RS11525	COG1496	oxidoreductase activity
WG31_RS11550	COG1742	UPF0060 membrane protein
WG31_RS11565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WG31_RS11580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WG31_RS11585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WG31_RS11595	COG0363	glucosamine-6-phosphate deaminase activity
WG31_RS11600	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WG31_RS11605	COG3265	gluconokinase activity
WG31_RS11630	COG0604	alcohol dehydrogenase
WG31_RS11640	COG3158	transport of potassium into the cell
WG31_RS11645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WG31_RS11665	COG0583	DNA-binding transcription factor activity
WG31_RS11700	COG0411	ABC transporter
WG31_RS11720	COG0784	Response regulator, receiver
WG31_RS11720	COG2198	Histidine kinase
WG31_RS11720	COG5002	protein histidine kinase activity
WG31_RS11725	COG0745	RESPONSE REGULATOR receiver
WG31_RS11740	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WG31_RS11745	COG0830	nickel cation binding
WG31_RS11750	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
WG31_RS11755	COG0804	urea catabolic process
WG31_RS11760	COG0832	Belongs to the urease beta subunit family
WG31_RS11765	COG0831	urea catabolic process
WG31_RS11770	COG0829	nickel cation binding
WG31_RS11775	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WG31_RS11780	COG3961	Belongs to the TPP enzyme family
WG31_RS11805	COG1393	Belongs to the ArsC family
WG31_RS11815	COG2818	Glycosylase
WG31_RS11825	COG0450	alkyl hydroperoxide reductase
WG31_RS11880	COG2271	Major facilitator Superfamily
WG31_RS11885	COG3473	Maleate cis-trans isomerase
WG31_RS11890	COG0596	Alpha beta hydrolase
WG31_RS11895	COG1335	isochorismatase
WG31_RS11900	COG2309	aminopeptidase activity
WG31_RS11905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WG31_RS11905	COG2010	Cytochrome c
WG31_RS11910	COG2080	2 iron, 2 sulfur cluster binding
WG31_RS11915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WG31_RS11920	COG1846	Transcriptional regulator
WG31_RS11965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WG31_RS11975	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
WG31_RS11995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WG31_RS11995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WG31_RS12000	COG0509	glycine decarboxylation via glycine cleavage system
WG31_RS12005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WG31_RS12010	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WG31_RS12015	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
WG31_RS12025	COG0583	DNA-binding transcription factor activity
WG31_RS12040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WG31_RS12045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WG31_RS12060	COG1185	polyribonucleotide nucleotidyltransferase activity
WG31_RS12065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WG31_RS12070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WG31_RS12075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WG31_RS12080	COG1127	ABC transporter
WG31_RS12085	COG3008	intermembrane lipid transfer
WG31_RS12085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WG31_RS12120	COG2274	protein secretion by the type I secretion system
WG31_RS12130	COG1410	methionine synthase
WG31_RS12130	COG0646	methionine synthase
WG31_RS12145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WG31_RS12155	COG3008	intermembrane lipid transfer
WG31_RS12160	COG2995	paraquat-inducible protein a
WG31_RS12170	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WG31_RS12175	COG0463	Glycosyl transferase, family 2
WG31_RS12180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WG31_RS12185	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WG31_RS12190	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WG31_RS12195	COG0356	it plays a direct role in the translocation of protons across the membrane
WG31_RS12205	COG0552	protein localization to endoplasmic reticulum
WG31_RS12210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WG31_RS12215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WG31_RS12220	COG0346	lactoylglutathione lyase activity
WG31_RS12230	COG0513	Belongs to the DEAD box helicase family
WG31_RS12250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WG31_RS12265	COG0704	Plays a role in the regulation of phosphate uptake
WG31_RS12270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WG31_RS12280	COG0573	inorganic phosphate transmembrane transporter activity
WG31_RS12285	COG0129	dihydroxy-acid dehydratase activity
WG31_RS12320	COG0489	protein tyrosine kinase activity
WG31_RS12335	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
WG31_RS12350	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WG31_RS12350	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WG31_RS12370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG31_RS12375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WG31_RS12380	COG1522	sequence-specific DNA binding
WG31_RS12385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WG31_RS12390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WG31_RS12405	COG0779	Required for maturation of 30S ribosomal subunits
WG31_RS12415	COG0542	response to heat
WG31_RS12430	COG0765	amino acid transport
WG31_RS12435	COG1126	abc transporter atp-binding protein
WG31_RS12445	COG4133	protoheme IX ABC transporter activity
WG31_RS12465	COG1295	ribonuclease BN
WG31_RS12475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WG31_RS12480	COG0511	ligase activity, forming carbon-carbon bonds
WG31_RS12485	COG0439	Biotin carboxylase
WG31_RS12490	COG2814	Major facilitator Superfamily
WG31_RS12495	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WG31_RS12510	COG0672	)-iron permease
WG31_RS12545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WG31_RS12555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WG31_RS12560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WG31_RS12565	COG0154	amidase activity
WG31_RS12570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WG31_RS12580	COG1132	(ABC) transporter
WG31_RS12590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WG31_RS12595	COG1194	a g-specific adenine glycosylase
WG31_RS12620	COG0495	leucyl-tRNA aminoacylation
WG31_RS12695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WG31_RS12705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WG31_RS12715	COG0590	tRNA wobble adenosine to inosine editing
WG31_RS12720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WG31_RS12725	COG1187	pseudouridine synthase activity
WG31_RS12730	COG0742	ribosomal rna small subunit methyltransferase
WG31_RS12735	COG0629	single-stranded DNA binding
WG31_RS12765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WG31_RS12770	COG0312	modulator of DNA gyrase
WG31_RS12775	COG0406	alpha-ribazole phosphatase activity
WG31_RS12795	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
WG31_RS12800	COG1091	dTDP-4-dehydrorhamnose reductase activity
WG31_RS12810	COG1674	ftsk spoiiie
WG31_RS12815	COG0564	pseudouridine synthase activity
WG31_RS12830	COG0482	sulfurtransferase activity
WG31_RS12840	COG1104	cysteine desulfurase activity
WG31_RS12845	COG1104	cysteine desulfurase activity
WG31_RS12850	COG2945	thiolester hydrolase activity
WG31_RS12860	COG0215	cysteine-tRNA ligase activity
WG31_RS12870	COG0285	dihydrofolate synthase activity
WG31_RS12875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WG31_RS12885	COG1074	ATP-dependent DNA helicase activity
WG31_RS12890	COG2887	Belongs to the helicase family. UvrD subfamily
WG31_RS12895	COG0802	atpase or kinase
WG31_RS12900	COG0745	RESPONSE REGULATOR receiver
WG31_RS12905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WG31_RS12915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WG31_RS12920	COG0037	tRNA processing
WG31_RS12930	COG2885	chlorophyll binding
WG31_RS12935	COG0823	Involved in the tonB-independent uptake of proteins
WG31_RS12955	COG0824	Thioesterase
WG31_RS12960	COG2255	four-way junction helicase activity
WG31_RS12965	COG0632	four-way junction helicase activity
WG31_RS12970	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WG31_RS12975	COG0217	transcriptional regulatory protein
WG31_RS12980	COG0653	protein targeting
WG31_RS12985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WG31_RS12990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
WG31_RS13000	COG0668	transmembrane transport
WG31_RS13015	COG0484	heat shock protein binding
WG31_RS13050	COG0776	regulation of translation
WG31_RS13070	COG1216	Glycosyl transferase, family 2
WG31_RS13085	COG0131	Imidazoleglycerol-phosphate dehydratase
WG31_RS13090	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WG31_RS13095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WG31_RS13100	COG0107	imidazoleglycerol-phosphate synthase activity
WG31_RS13105	COG0140	phosphoribosyl-ATP diphosphatase activity
WG31_RS13115	COG0778	Nitroreductase
WG31_RS13155	COG0357	Ribosomal RNA small subunit methyltransferase G
WG31_RS13160	COG0445	tRNA wobble uridine modification
WG31_RS13165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WG31_RS13195	COG1611	Belongs to the LOG family
WG31_RS13210	COG1981	membrane
WG31_RS13215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WG31_RS13220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III