locus-tag	class	description
FAI40_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FAI40_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FAI40_RS00025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FAI40_RS00030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FAI40_RS00045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FAI40_RS00050	COG0318	PFAM AMP-dependent synthetase and ligase
FAI40_RS00055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FAI40_RS00090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FAI40_RS00095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FAI40_RS00100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FAI40_RS00110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FAI40_RS00115	COG3590	peptidase
FAI40_RS00120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FAI40_RS00140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FAI40_RS00165	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_RS00175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FAI40_RS00180	COG1702	phosphate starvation-inducible protein PhoH
FAI40_RS00185	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FAI40_RS00195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FAI40_RS00200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FAI40_RS00205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FAI40_RS00210	COG0142	geranyltranstransferase activity
FAI40_RS00215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FAI40_RS00220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FAI40_RS00220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FAI40_RS00225	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FAI40_RS00230	COG0259	pyridoxamine-phosphate oxidase activity
FAI40_RS00240	COG1663	tetraacyldisaccharide 4'-kinase activity
FAI40_RS00255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FAI40_RS00260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FAI40_RS00275	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FAI40_RS00280	COG1160	GTP binding
FAI40_RS00295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FAI40_RS00300	COG0859	PFAM glycosyl transferase family 9
FAI40_RS00305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FAI40_RS00310	COG0237	dephospho-CoA kinase activity
FAI40_RS00325	COG0084	hydrolase, TatD family'
FAI40_RS00330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FAI40_RS00335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FAI40_RS00340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FAI40_RS00345	COG1686	Belongs to the peptidase S11 family
FAI40_RS00365	COG1968	undecaprenyl-diphosphatase activity
FAI40_RS00380	COG2890	protein-(glutamine-N5) methyltransferase activity
FAI40_RS00385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FAI40_RS00390	COG0124	histidyl-tRNA synthetase
FAI40_RS00395	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FAI40_RS00410	COG0527	aspartate kinase activity
FAI40_RS00415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FAI40_RS00450	COG0321	lipoyl(octanoyl) transferase activity
FAI40_RS00480	COG1136	(ABC) transporter
FAI40_RS00485	COG4591	ABC-type transport system involved in lipoprotein release permease component
FAI40_RS00490	COG0442	prolyl-tRNA aminoacylation
FAI40_RS00500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FAI40_RS00515	COG0776	regulation of translation
FAI40_RS00525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FAI40_RS00530	COG0740	serine-type endopeptidase activity
FAI40_RS00535	COG0544	peptidyl-prolyl cis-trans isomerase activity
FAI40_RS00550	COG0513	Belongs to the DEAD box helicase family
FAI40_RS00555	COG0316	Belongs to the HesB IscA family
FAI40_RS00560	COG2151	metal-sulfur cluster biosynthetic enzyme
FAI40_RS00565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FAI40_RS00570	COG0719	Fe-S assembly protein
FAI40_RS00575	COG0396	ATPase activity
FAI40_RS00580	COG0719	Fe-S assembly protein
FAI40_RS00590	COG2733	membrane
FAI40_RS00590	COG2733	membrane
FAI40_RS00600	COG1335	isochorismatase
FAI40_RS00605	COG0436	Aminotransferase
FAI40_RS00615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FAI40_RS00620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FAI40_RS00625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FAI40_RS00630	COG3750	Belongs to the UPF0335 family
FAI40_RS00635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FAI40_RS00645	COG2001	Belongs to the MraZ family
FAI40_RS00650	COG0275	rRNA processing
FAI40_RS00665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FAI40_RS00675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FAI40_RS00680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FAI40_RS00690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FAI40_RS00695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FAI40_RS00700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FAI40_RS00705	COG1181	Belongs to the D-alanine--D-alanine ligase family
FAI40_RS00710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FAI40_RS00735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FAI40_RS00740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FAI40_RS00745	COG0497	DNA recombination
FAI40_RS00750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FAI40_RS00755	COG1253	flavin adenine dinucleotide binding
FAI40_RS00770	COG2824	Alkylphosphonate utilization operon protein PhnA
FAI40_RS00800	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FAI40_RS00835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FAI40_RS00840	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FAI40_RS00845	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FAI40_RS00850	COG0861	Integral membrane protein TerC family
FAI40_RS00855	COG0588	phosphoglycerate mutase activity
FAI40_RS00890	COG0513	Belongs to the DEAD box helicase family
FAI40_RS00895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FAI40_RS00905	COG0113	porphobilinogen synthase activity
FAI40_RS00910	COG0792	nuclease activity
FAI40_RS00920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FAI40_RS00935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FAI40_RS00940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FAI40_RS00945	COG0861	Integral membrane protein TerC family
FAI40_RS00955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FAI40_RS00960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FAI40_RS00965	COG0508	dehydrogenase complex catalyzes the overall conversion of
FAI40_RS00975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FAI40_RS00985	COG0149	triose-phosphate isomerase activity
FAI40_RS00995	COG0504	CTP synthase activity
FAI40_RS01000	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FAI40_RS01015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FAI40_RS01025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FAI40_RS01030	COG0322	excinuclease ABC activity
FAI40_RS01040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FAI40_RS01040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FAI40_RS01060	COG0837	glucose binding
FAI40_RS01065	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_RS01075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FAI40_RS01080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FAI40_RS01090	COG0673	inositol 2-dehydrogenase activity
FAI40_RS01095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FAI40_RS01110	COG0254	rRNA binding
FAI40_RS01120	COG0210	DNA helicase
FAI40_RS01125	COG2264	protein methyltransferase activity
FAI40_RS01135	COG0006	proline dipeptidase activity
FAI40_RS01155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FAI40_RS01165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FAI40_RS01170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FAI40_RS01180	COG0284	orotidine-5'-phosphate decarboxylase activity
FAI40_RS01210	COG4221	oxidoreductase activity
FAI40_RS01250	COG4993	Dehydrogenase
FAI40_RS01260	COG0149	triose-phosphate isomerase activity
FAI40_RS01270	COG0488	(ABC) transporter
FAI40_RS01280	COG0513	Belongs to the DEAD box helicase family
FAI40_RS01290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FAI40_RS01295	COG0154	amidase activity
FAI40_RS01300	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FAI40_RS01305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FAI40_RS01315	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FAI40_RS01320	COG0667	Aldo Keto reductase
FAI40_RS01340	COG2814	Major facilitator Superfamily
FAI40_RS01345	COG1566	PFAM secretion protein HlyD family protein
FAI40_RS01355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FAI40_RS01360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FAI40_RS01370	COG1185	polyribonucleotide nucleotidyltransferase activity
FAI40_RS01375	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FAI40_RS01380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FAI40_RS01385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FAI40_RS01390	COG5373	membrane
FAI40_RS01390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FAI40_RS01390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FAI40_RS01390	COG5373	membrane
FAI40_RS01405	COG0779	Required for maturation of 30S ribosomal subunits
FAI40_RS01420	COG0765	amino acid transport
FAI40_RS01425	COG1126	abc transporter atp-binding protein
FAI40_RS01430	COG4133	protoheme IX ABC transporter activity
FAI40_RS01435	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FAI40_RS01440	COG0439	Biotin carboxylase
FAI40_RS01445	COG0511	ligase activity, forming carbon-carbon bonds
FAI40_RS01465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FAI40_RS01470	COG0540	Belongs to the ATCase OTCase family
FAI40_RS01475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FAI40_RS01480	COG0758	DNA mediated transformation
FAI40_RS01485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FAI40_RS01490	COG2885	chlorophyll binding
FAI40_RS01490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FAI40_RS01505	COG0187	DNA topoisomerase II activity
FAI40_RS01520	COG1432	Conserved Protein
FAI40_RS01595	COG4381	Mu-like prophage protein gp46
FAI40_RS01835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FAI40_RS01840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FAI40_RS01860	COG2194	sulfuric ester hydrolase activity
FAI40_RS01865	COG2194	sulfuric ester hydrolase activity
FAI40_RS01885	COG0673	inositol 2-dehydrogenase activity
FAI40_RS01920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FAI40_RS01925	COG4716	Myosin-crossreactive antigen
FAI40_RS01930	COG4716	Myosin-crossreactive antigen
FAI40_RS01950	COG1692	metallophosphoesterase
FAI40_RS01955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FAI40_RS01975	COG4774	siderophore transport
FAI40_RS01990	COG1509	lysine 2,3-aminomutase activity
FAI40_RS01995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FAI40_RS02000	COG0483	inositol monophosphate 1-phosphatase activity
FAI40_RS02010	COG0481	GTPase activity
FAI40_RS02020	COG2252	PERMEase
FAI40_RS02035	COG0142	geranyltranstransferase activity
FAI40_RS02040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FAI40_RS02045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FAI40_RS02050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FAI40_RS02065	COG0180	Tryptophanyl-tRNA synthetase
FAI40_RS02070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FAI40_RS02080	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FAI40_RS02085	COG0072	phenylalanine-tRNA ligase activity
FAI40_RS02085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FAI40_RS02090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FAI40_RS02095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FAI40_RS02100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FAI40_RS02105	COG2166	iron-sulfur cluster assembly
FAI40_RS02130	COG0688	phosphatidylethanolamine metabolic process
FAI40_RS02150	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FAI40_RS02155	COG1218	3'(2'),5'-bisphosphate nucleotidase
FAI40_RS02160	COG0009	L-threonylcarbamoyladenylate synthase
FAI40_RS02165	COG0795	lipopolysaccharide-transporting ATPase activity
FAI40_RS02185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FAI40_RS02195	COG0359	binds to the 23S rRNA
FAI40_RS02200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FAI40_RS02205	COG0360	Binds together with S18 to 16S ribosomal RNA
FAI40_RS02215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FAI40_RS02220	COG0358	DNA primase activity
FAI40_RS02230	COG0505	Belongs to the CarA family
FAI40_RS02235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FAI40_RS02240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FAI40_RS02245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FAI40_RS02265	COG1902	pentaerythritol trinitrate reductase activity
FAI40_RS02280	COG0793	Belongs to the peptidase S41A family
FAI40_RS02285	COG0494	nUDIX hydrolase
FAI40_RS02290	COG1132	(ABC) transporter
FAI40_RS02295	COG0617	tRNA 3'-terminal CCA addition
FAI40_RS02310	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FAI40_RS02315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FAI40_RS02340	COG0203	ribosomal protein L17
FAI40_RS02345	COG0202	RNA polymerase activity
FAI40_RS02350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FAI40_RS02355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FAI40_RS02360	COG0563	adenylate kinase activity
FAI40_RS02365	COG0201	protein transport
FAI40_RS02370	COG0200	Binds to the 23S rRNA
FAI40_RS02375	COG1841	ribosomal large subunit assembly
FAI40_RS02380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FAI40_RS02385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FAI40_RS02390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FAI40_RS02395	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FAI40_RS02400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FAI40_RS02405	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FAI40_RS02410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FAI40_RS02415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FAI40_RS02420	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FAI40_RS02425	COG0255	Belongs to the universal ribosomal protein uL29 family
FAI40_RS02430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FAI40_RS02435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FAI40_RS02440	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FAI40_RS02445	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FAI40_RS02450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FAI40_RS02455	COG0089	rRNA binding
FAI40_RS02460	COG0088	Forms part of the polypeptide exit tunnel
FAI40_RS02465	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FAI40_RS02470	COG0051	transcription antitermination factor activity, RNA binding
FAI40_RS02475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FAI40_RS02480	COG0049	tRNA binding
FAI40_RS02485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FAI40_RS02490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FAI40_RS02495	COG0085	RNA polymerase activity
FAI40_RS02505	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FAI40_RS02510	COG0081	regulation of translation
FAI40_RS02515	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FAI40_RS02520	COG0850	regulation of cytokinetic process
FAI40_RS02530	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FAI40_RS02545	COG0495	leucyl-tRNA aminoacylation
FAI40_RS02575	COG1956	GAF domain-containing protein
FAI40_RS02590	COG1280	lysine exporter protein (LysE YggA)
FAI40_RS02605	COG0167	dihydroorotate dehydrogenase activity
FAI40_RS02610	COG0246	Mannitol dehydrogenase
FAI40_RS02615	COG3265	gluconokinase activity
FAI40_RS02625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FAI40_RS02635	COG0513	Belongs to the DEAD box helicase family
FAI40_RS02645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FAI40_RS02650	COG1061	Type III restriction enzyme res subunit
FAI40_RS02660	COG1002	Type II restriction enzyme, methylase subunits
FAI40_RS02680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FAI40_RS02685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FAI40_RS02690	COG0590	tRNA wobble adenosine to inosine editing
FAI40_RS02695	COG1187	pseudouridine synthase activity
FAI40_RS02700	COG0742	ribosomal rna small subunit methyltransferase
FAI40_RS02705	COG1674	ftsk spoiiie
FAI40_RS02710	COG0564	pseudouridine synthase activity
FAI40_RS02775	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FAI40_RS02785	COG4245	von Willebrand factor, type A
FAI40_RS02790	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FAI40_RS02805	COG1763	Mo-molybdopterin cofactor biosynthetic process
FAI40_RS02825	COG4221	oxidoreductase activity
FAI40_RS02830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FAI40_RS02845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FAI40_RS02850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FAI40_RS02855	COG0713	ATP synthesis coupled electron transport
FAI40_RS02860	COG0839	Belongs to the complex I subunit 6 family
FAI40_RS02895	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FAI40_RS02940	COG0564	pseudouridine synthase activity
FAI40_RS02960	COG0126	phosphoglycerate kinase activity
FAI40_RS03000	COG0582	viral genome integration into host DNA
FAI40_RS03120	COG1253	flavin adenine dinucleotide binding
FAI40_RS03125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FAI40_RS03175	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FAI40_RS03185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FAI40_RS03195	COG1074	ATP-dependent DNA helicase activity
FAI40_RS03200	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FAI40_RS03220	COG0802	atpase or kinase
FAI40_RS03225	COG0492	ferredoxin-NADP+ reductase activity
FAI40_RS03230	COG1247	-acetyltransferase
FAI40_RS03285	COG1217	gtp-binding protein TYPA
FAI40_RS03290	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FAI40_RS03350	COG2244	polysaccharide biosynthetic process
FAI40_RS03355	COG1012	belongs to the aldehyde dehydrogenase family
FAI40_RS03360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FAI40_RS03375	COG2194	sulfuric ester hydrolase activity
FAI40_RS03380	COG2194	sulfuric ester hydrolase activity
FAI40_RS03385	COG1597	lipid kinase activity
FAI40_RS03475	COG0646	methionine synthase
FAI40_RS03475	COG1410	methionine synthase
FAI40_RS03490	COG0659	secondary active sulfate transmembrane transporter activity
FAI40_RS03510	COG2226	methyltransferase
FAI40_RS03545	COG1073	alpha beta
FAI40_RS03555	COG0309	Hydrogenase expression formation protein (HypE)
FAI40_RS03560	COG0409	Hydrogenase expression formation protein
FAI40_RS03565	COG0298	carbon dioxide binding
FAI40_RS03570	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FAI40_RS03580	COG0375	protein maturation
FAI40_RS03585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FAI40_RS03590	COG0651	ATP synthesis coupled electron transport
FAI40_RS03595	COG0650	Formate hydrogenlyase subunit 4
FAI40_RS03600	COG3261	NADH dehydrogenase
FAI40_RS03600	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FAI40_RS03610	COG3260	NADH ubiquinone oxidoreductase 20
FAI40_RS03620	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FAI40_RS03625	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FAI40_RS03630	COG3383	formate dehydrogenase (NAD+) activity
FAI40_RS03635	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FAI40_RS03650	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FAI40_RS03690	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FAI40_RS03695	COG0303	'Molybdopterin
FAI40_RS03710	COG0756	dUTP diphosphatase activity
FAI40_RS03805	COG1063	alcohol dehydrogenase
FAI40_RS03840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FAI40_RS03845	COG3177	Filamentation induced by cAMP protein fic
FAI40_RS03960	COG0657	acetylesterase activity
FAI40_RS04095	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FAI40_RS04105	COG0732	type I restriction modification DNA specificity domain
FAI40_RS04210	COG1063	alcohol dehydrogenase
FAI40_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_RS04275	COG0667	Aldo Keto reductase
FAI40_RS04515	COG0602	queuosine metabolic process
FAI40_RS04860	COG1979	alcohol dehydrogenase
FAI40_RS04885	COG1401	restriction endodeoxyribonuclease activity
FAI40_RS04900	COG0038	chloride channel
FAI40_RS04905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FAI40_RS04915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FAI40_RS04915	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FAI40_RS04920	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FAI40_RS04925	COG0405	Gamma-glutamyltransferase
FAI40_RS04955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FAI40_RS04975	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FAI40_RS04985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FAI40_RS04990	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FAI40_RS05000	COG4774	siderophore transport
FAI40_RS05005	COG3118	belongs to the thioredoxin family
FAI40_RS05015	COG0445	tRNA wobble uridine modification
FAI40_RS05020	COG0357	Ribosomal RNA small subunit methyltransferase G
FAI40_RS05030	COG1475	DNA binding
FAI40_RS05055	COG2154	pterin-4-alpha-carbinolamine dehydratase
FAI40_RS05060	COG3186	Phenylalanine-4-hydroxylase
FAI40_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_RS05075	COG0438	transferase activity, transferring glycosyl groups
FAI40_RS05080	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FAI40_RS05080	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FAI40_RS05085	COG0307	riboflavin synthase, alpha
FAI40_RS05090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FAI40_RS05090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FAI40_RS05095	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FAI40_RS05110	COG0740	serine-type endopeptidase activity
FAI40_RS05130	COG0534	Mate efflux family protein
FAI40_RS05145	COG1981	membrane
FAI40_RS05150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FAI40_RS05155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FAI40_RS05160	COG0424	maF-like protein
FAI40_RS05220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FAI40_RS05255	COG4774	siderophore transport
FAI40_RS05280	COG4232	protein-disulfide reductase activity
FAI40_RS05300	COG0756	dUTP diphosphatase activity
FAI40_RS05325	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FAI40_RS05330	COG4974	Belongs to the 'phage' integrase family
FAI40_RS05340	COG0629	single-stranded DNA binding
FAI40_RS05355	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FAI40_RS05360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FAI40_RS05360	COG1017	nitric oxide dioxygenase activity
FAI40_RS05370	COG0602	queuosine metabolic process
FAI40_RS05380	COG0753	catalase activity
FAI40_RS05385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FAI40_RS05395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FAI40_RS05400	COG1127	ABC transporter
FAI40_RS05415	COG4774	siderophore transport
FAI40_RS05435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FAI40_RS05440	COG0601	transmembrane transport
FAI40_RS05445	COG0747	negative chemotaxis
FAI40_RS05470	COG4988	ABC transporter
FAI40_RS05475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FAI40_RS05480	COG1271	oxidase subunit
FAI40_RS05485	COG1294	oxidase, subunit
FAI40_RS05500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FAI40_RS05500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FAI40_RS05505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FAI40_RS05540	COG2267	carboxylic ester hydrolase activity
FAI40_RS05565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FAI40_RS05575	COG0326	Molecular chaperone. Has ATPase activity
FAI40_RS05580	COG3961	Belongs to the TPP enzyme family
FAI40_RS05585	COG1064	alcohol dehydrogenase
FAI40_RS05590	COG1012	belongs to the aldehyde dehydrogenase family
FAI40_RS05635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FAI40_RS05645	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FAI40_RS05650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FAI40_RS05685	COG4774	siderophore transport
FAI40_RS05690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FAI40_RS05695	COG0285	dihydrofolate synthase activity
FAI40_RS05700	COG0305	Participates in initiation and elongation during chromosome replication
FAI40_RS05715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FAI40_RS05720	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FAI40_RS05730	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FAI40_RS05765	COG0668	transmembrane transport
FAI40_RS05775	COG1194	a g-specific adenine glycosylase
FAI40_RS05785	COG0560	Phosphoserine phosphatase
FAI40_RS05790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FAI40_RS05795	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FAI40_RS05800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FAI40_RS05810	COG1940	carbohydrate kinase activity
FAI40_RS05820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FAI40_RS05825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FAI40_RS05835	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FAI40_RS05840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FAI40_RS05845	COG0424	maF-like protein
FAI40_RS05855	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FAI40_RS05865	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FAI40_RS05880	COG0656	L-ascorbic acid biosynthetic process
FAI40_RS05900	COG2134	cdp-diacylglycerol pyrophosphatase
FAI40_RS05980	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FAI40_RS05985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FAI40_RS06005	COG2995	paraquat-inducible protein a
FAI40_RS06010	COG3008	intermembrane lipid transfer
FAI40_RS06020	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FAI40_RS06050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FAI40_RS06055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FAI40_RS06060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FAI40_RS06065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FAI40_RS06130	COG4957	zinc ion binding
FAI40_RS06160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FAI40_RS06175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FAI40_RS06180	COG1496	oxidoreductase activity
FAI40_RS06195	COG0193	aminoacyl-tRNA hydrolase activity
FAI40_RS06210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FAI40_RS06215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FAI40_RS06220	COG0799	negative regulation of ribosome biogenesis
FAI40_RS06225	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FAI40_RS06275	COG4957	zinc ion binding
FAI40_RS06305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FAI40_RS06320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FAI40_RS06325	COG1496	oxidoreductase activity
FAI40_RS06330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FAI40_RS06335	COG0193	aminoacyl-tRNA hydrolase activity
FAI40_RS06340	COG0012	GTP binding
FAI40_RS06345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FAI40_RS06350	COG0799	negative regulation of ribosome biogenesis
FAI40_RS06355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FAI40_RS06365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FAI40_RS06430	COG1686	Belongs to the peptidase S11 family
FAI40_RS06435	COG0024	Methionine aminopeptidase
FAI40_RS06440	COG0405	Gamma-glutamyltransferase
FAI40_RS06455	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FAI40_RS06460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FAI40_RS06465	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_RS06475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FAI40_RS06480	COG0539	negative regulation of cytoplasmic translation
FAI40_RS06485	COG2837	iron assimilation
FAI40_RS06505	COG0612	Peptidase, M16
FAI40_RS06515	COG1304	FMN binding
FAI40_RS06520	COG2011	ABC-type metal ion transport system permease component
FAI40_RS06530	COG1464	Belongs to the NlpA lipoprotein family
FAI40_RS06535	COG0531	amino acid
FAI40_RS06550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FAI40_RS06555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FAI40_RS06570	COG1660	Displays ATPase and GTPase activities
FAI40_RS06575	COG3264	Mechanosensitive ion channel
FAI40_RS06575	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FAI40_RS06590	COG5000	phosphorelay sensor kinase activity
FAI40_RS06595	COG2204	response regulator
FAI40_RS06600	COG1923	regulation of RNA biosynthetic process
FAI40_RS06605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FAI40_RS06615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FAI40_RS06625	COG0604	alcohol dehydrogenase
FAI40_RS06625	COG3321	synthase
FAI40_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_RS06630	COG0318	PFAM AMP-dependent synthetase and ligase
FAI40_RS06660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FAI40_RS06670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FAI40_RS06675	COG0303	'Molybdopterin
FAI40_RS06690	COG0315	cyclic pyranopterin monophosphate synthase activity
FAI40_RS06690	COG0746	molybdenum cofactor guanylyltransferase activity
FAI40_RS06700	COG0314	molybdopterin synthase activity
FAI40_RS06715	COG2983	Belongs to the UPF0260 family
FAI40_RS06730	COG1566	PFAM secretion protein HlyD family protein
FAI40_RS06735	COG1538	Outer membrane efflux protein
FAI40_RS06835	COG0831	urea catabolic process
FAI40_RS06845	COG0804	urea catabolic process
FAI40_RS06855	COG0830	nickel cation binding
FAI40_RS06860	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FAI40_RS06865	COG0829	nickel cation binding
FAI40_RS06870	COG4413	Urea transporter
FAI40_RS06885	COG1280	lysine exporter protein (LysE YggA)
FAI40_RS06900	COG3038	cytochrome b561
FAI40_RS06910	COG4106	trans-aconitate 2-methyltransferase activity
FAI40_RS06910	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FAI40_RS06915	COG2226	methyltransferase
FAI40_RS06925	COG0156	8-amino-7-oxononanoate synthase activity
FAI40_RS06930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FAI40_RS06940	COG2274	protein secretion by the type I secretion system
FAI40_RS06975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FAI40_RS06980	COG1216	Glycosyl transferase, family 2
FAI40_RS06980	COG0438	transferase activity, transferring glycosyl groups
FAI40_RS06990	COG0581	inorganic phosphate transmembrane transporter activity
FAI40_RS06995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FAI40_RS07005	COG1113	amino acid transport
FAI40_RS07015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FAI40_RS07040	COG1942	4-Oxalocrotonate Tautomerase
FAI40_RS07070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FAI40_RS07075	COG2945	thiolester hydrolase activity
FAI40_RS07080	COG1104	cysteine desulfurase activity
FAI40_RS07085	COG1104	cysteine desulfurase activity
FAI40_RS07095	COG0482	sulfurtransferase activity
FAI40_RS07105	COG3634	alkyl hydroperoxide reductase activity
FAI40_RS07165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FAI40_RS07170	COG0251	oxidation-reduction process
FAI40_RS07175	COG0384	phenazine biosynthesis protein PhzF
FAI40_RS07185	COG2957	Belongs to the agmatine deiminase family
FAI40_RS07190	COG1741	Belongs to the pirin family
FAI40_RS07210	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FAI40_RS07210	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FAI40_RS07245	COG0174	glutamine synthetase
FAI40_RS07250	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FAI40_RS07255	COG0406	alpha-ribazole phosphatase activity
FAI40_RS07260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FAI40_RS07275	COG1091	dTDP-4-dehydrorhamnose reductase activity
FAI40_RS07280	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FAI40_RS07285	COG2249	NAD(P)H dehydrogenase (quinone) activity
FAI40_RS07295	COG0194	GDP metabolic process
FAI40_RS07325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FAI40_RS07330	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FAI40_RS07335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FAI40_RS07340	COG0484	heat shock protein binding
FAI40_RS07345	COG0443	Heat shock 70 kDa protein
FAI40_RS07365	COG0717	Belongs to the dCTP deaminase family
FAI40_RS07370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FAI40_RS07390	COG2814	Major facilitator Superfamily
FAI40_RS07395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FAI40_RS07415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FAI40_RS07420	COG0552	protein localization to endoplasmic reticulum
FAI40_RS07425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FAI40_RS07430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FAI40_RS07435	COG0513	Belongs to the DEAD box helicase family
FAI40_RS07440	COG1678	Uncharacterized ACR, COG1678
FAI40_RS07445	COG0542	response to heat
FAI40_RS07490	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FAI40_RS07560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FAI40_RS07565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FAI40_RS07575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FAI40_RS07580	COG0196	riboflavin kinase activity
FAI40_RS07585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FAI40_RS07590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FAI40_RS07600	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FAI40_RS07610	COG0741	lytic transglycosylase activity
FAI40_RS07620	COG3180	Ammonia monooxygenase
FAI40_RS07630	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FAI40_RS07630	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FAI40_RS07635	COG2942	2-epimerase
FAI40_RS07645	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FAI40_RS07655	COG0778	Nitroreductase
FAI40_RS07660	COG1214	PFAM Peptidase M22, glycoprotease
FAI40_RS07685	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FAI40_RS07715	COG2835	tetraacyldisaccharide 4'-kinase activity
FAI40_RS07755	COG4771	TonB-dependent receptor
FAI40_RS07760	COG0628	permease
FAI40_RS07765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FAI40_RS07775	COG0488	(ABC) transporter
FAI40_RS07785	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FAI40_RS07815	COG1088	dTDP-glucose 4,6-dehydratase activity
FAI40_RS07820	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FAI40_RS07845	COG2864	formate dehydrogenase
FAI40_RS07850	COG0437	4 iron, 4 sulfur cluster binding
FAI40_RS07855	COG3383	formate dehydrogenase (NAD+) activity
FAI40_RS07855	COG0243	molybdopterin cofactor binding
FAI40_RS07875	COG0723	plastoquinol--plastocyanin reductase activity
FAI40_RS07880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FAI40_RS07890	COG0473	3-isopropylmalate dehydrogenase activity
FAI40_RS07940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FAI40_RS07955	COG0583	DNA-binding transcription factor activity
FAI40_RS07985	COG0277	FAD linked oxidase domain protein
FAI40_RS07990	COG0604	alcohol dehydrogenase
FAI40_RS08005	COG0477	Major facilitator Superfamily
FAI40_RS08040	COG1475	DNA binding
FAI40_RS08125	COG2815	serine threonine protein kinase
FAI40_RS08125	COG0515	serine threonine protein kinase
FAI40_RS08140	COG1360	Flagellar Motor Protein
FAI40_RS08240	COG2986	histidine ammonia-lyase
FAI40_RS08265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FAI40_RS08280	COG3041	Addiction module toxin RelE StbE family
FAI40_RS08285	COG3077	Addiction module antitoxin, RelB DinJ family
FAI40_RS08335	COG3504	Conjugal transfer protein
FAI40_RS08340	COG3701	Conjugal transfer protein
FAI40_RS08345	COG3451	type IV secretory pathway VirB4
FAI40_RS08360	COG4962	Type ii secretion system protein e
FAI40_RS08385	COG0347	Belongs to the P(II) protein family
FAI40_RS08395	COG0004	ammonium transporteR
FAI40_RS08400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FAI40_RS08405	COG0228	four-way junction DNA binding
FAI40_RS08410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FAI40_RS08415	COG0336	Belongs to the RNA methyltransferase TrmD family
FAI40_RS08420	COG0335	large ribosomal subunit rRNA binding
FAI40_RS08450	COG1297	OPT oligopeptide transporter protein
FAI40_RS08470	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FAI40_RS08475	COG0328	RNA-DNA hybrid ribonuclease activity
FAI40_RS08580	COG0583	DNA-binding transcription factor activity
FAI40_RS08585	COG0655	NAD(P)H dehydrogenase (quinone) activity
FAI40_RS08600	COG0531	amino acid
FAI40_RS08615	COG1045	serine acetyltransferase
FAI40_RS08670	COG0156	8-amino-7-oxononanoate synthase activity
FAI40_RS08680	COG0281	malic enzyme
FAI40_RS08690	COG3088	subunit of a heme lyase
FAI40_RS08700	COG1138	Cytochrome C-type biogenesis protein
FAI40_RS08705	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FAI40_RS08740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FAI40_RS08745	COG0564	pseudouridine synthase activity
FAI40_RS08755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FAI40_RS08755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FAI40_RS08770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FAI40_RS08775	COG0463	Glycosyl transferase, family 2
FAI40_RS08805	COG0489	protein tyrosine kinase activity
FAI40_RS08815	COG0484	heat shock protein binding
FAI40_RS08850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FAI40_RS08880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FAI40_RS08890	COG0356	it plays a direct role in the translocation of protons across the membrane
FAI40_RS08895	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FAI40_RS08905	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FAI40_RS08915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FAI40_RS08930	COG0343	queuine tRNA-ribosyltransferase activity
FAI40_RS08935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FAI40_RS08960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FAI40_RS08965	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FAI40_RS08975	COG0129	dihydroxy-acid dehydratase activity
FAI40_RS08980	COG0800	Aldolase
FAI40_RS08990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FAI40_RS08995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FAI40_RS09000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FAI40_RS09015	COG1959	2 iron, 2 sulfur cluster binding
FAI40_RS09030	COG1252	NADH dehydrogenase
FAI40_RS09035	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FAI40_RS09040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FAI40_RS09045	COG0653	protein targeting
FAI40_RS09050	COG0217	transcriptional regulatory protein
FAI40_RS09055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FAI40_RS09060	COG0632	four-way junction helicase activity
FAI40_RS09065	COG2255	four-way junction helicase activity
FAI40_RS09070	COG0824	Thioesterase
FAI40_RS09080	COG0848	biopolymer transport protein
FAI40_RS09090	COG0823	Involved in the tonB-independent uptake of proteins
FAI40_RS09095	COG2885	chlorophyll binding
FAI40_RS09105	COG0037	tRNA processing
FAI40_RS09110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FAI40_RS09115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FAI40_RS09120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FAI40_RS09125	COG0166	Belongs to the GPI family
FAI40_RS09130	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FAI40_RS09135	COG0363	glucosamine-6-phosphate deaminase activity
FAI40_RS09140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FAI40_RS09145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FAI40_RS09175	COG0352	thiamine-phosphate diphosphorylase activity
FAI40_RS09180	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FAI40_RS09195	COG1570	exodeoxyribonuclease VII activity
FAI40_RS09200	COG1530	ribonuclease E activity
FAI40_RS09205	COG1388	LysM domain
FAI40_RS09205	COG0860	N-Acetylmuramoyl-L-alanine amidase
FAI40_RS09225	COG0768	penicillin binding
FAI40_RS09230	COG0772	Belongs to the SEDS family
FAI40_RS09235	COG3961	Belongs to the TPP enzyme family
FAI40_RS09240	COG3961	Belongs to the TPP enzyme family
FAI40_RS09245	COG0751	glycine-tRNA ligase activity
FAI40_RS09250	COG0752	glycyl-tRNA synthetase alpha subunit
FAI40_RS09260	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FAI40_RS09280	COG0708	Exodeoxyribonuclease III
FAI40_RS09285	COG0316	Belongs to the HesB IscA family
FAI40_RS09290	COG0018	arginyl-trna synthetase
FAI40_RS09300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FAI40_RS09305	COG0805	protein transport
FAI40_RS09310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FAI40_RS09365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FAI40_RS09385	COG0215	cysteine-tRNA ligase activity
FAI40_RS09395	COG2814	Major facilitator Superfamily
FAI40_RS09400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FAI40_RS09405	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FAI40_RS09415	COG0288	reversible hydration of carbon dioxide
FAI40_RS09420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FAI40_RS09430	COG4974	Belongs to the 'phage' integrase family
FAI40_RS09435	COG0825	malonyl-CoA metabolic process
FAI40_RS09440	COG1546	Belongs to the CinA family
FAI40_RS09440	COG1058	Belongs to the CinA family
FAI40_RS09445	COG0494	nUDIX hydrolase
FAI40_RS09450	COG1862	Preprotein translocase
FAI40_RS09460	COG1758	RNA polymerase activity
FAI40_RS09465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FAI40_RS09470	COG0736	holo-[acyl-carrier-protein] synthase activity
FAI40_RS09475	COG0681	Belongs to the peptidase S26 family
FAI40_RS09480	COG0571	ribonuclease III activity
FAI40_RS09485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FAI40_RS09490	COG0528	UMP kinase activity
FAI40_RS09495	COG0233	cytoplasmic translational termination
FAI40_RS09500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FAI40_RS09505	COG0575	Belongs to the CDS family
FAI40_RS09510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FAI40_RS09515	COG0750	zinc metalloprotease
FAI40_RS09520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FAI40_RS09530	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FAI40_RS09535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FAI40_RS09540	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FAI40_RS09550	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FAI40_RS09555	COG0594	ribonuclease P activity
FAI40_RS09560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FAI40_RS09565	COG0706	membrane insertase activity
FAI40_RS09570	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FAI40_RS09575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FAI40_RS09580	COG2171	N-acyltransferase activity
FAI40_RS09585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FAI40_RS09595	COG0101	tRNA pseudouridine synthase activity
FAI40_RS09600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FAI40_RS09605	COG0242	peptide deformylase activity
FAI40_RS09610	COG1137	ATPase activity
FAI40_RS09625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FAI40_RS09625	COG0517	IMP dehydrogenase activity
FAI40_RS09650	COG0556	nucleotide-excision repair
FAI40_RS09660	COG0189	ligase activity
FAI40_RS09665	COG2226	methyltransferase
FAI40_RS09670	COG0612	Peptidase, M16
FAI40_RS09675	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FAI40_RS09680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FAI40_RS09690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FAI40_RS09695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FAI40_RS09710	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FAI40_RS09730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FAI40_RS09735	COG1120	ATPase activity
FAI40_RS09740	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FAI40_RS09745	COG0459	protein refolding
FAI40_RS09760	COG0392	lysyltransferase activity
FAI40_RS09765	COG0670	Belongs to the BI1 family
FAI40_RS09775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FAI40_RS09790	COG0105	UTP biosynthetic process
FAI40_RS09800	COG0019	diaminopimelate decarboxylase activity
FAI40_RS09820	COG0519	Catalyzes the synthesis of GMP from XMP
FAI40_RS09820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FAI40_RS09830	COG0469	pyruvate kinase activity
FAI40_RS09840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FAI40_RS09855	COG1562	ergosterol biosynthetic process
FAI40_RS09860	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FAI40_RS09865	COG1657	PFAM Prenyltransferase squalene oxidase
FAI40_RS09875	COG0052	Belongs to the universal ribosomal protein uS2 family
FAI40_RS09880	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FAI40_RS09885	COG1381	Involved in DNA repair and RecF pathway recombination
FAI40_RS09890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FAI40_RS09895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FAI40_RS09905	COG0606	chelatase, subunit chli
FAI40_RS09910	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FAI40_RS09915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FAI40_RS09920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FAI40_RS09925	COG1278	Cold shock
FAI40_RS09930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FAI40_RS09935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FAI40_RS09940	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FAI40_RS10130	COG3750	Belongs to the UPF0335 family
FAI40_RS10240	COG0582	viral genome integration into host DNA
FAI40_RS10255	COG0525	valine-tRNA ligase activity
FAI40_RS10260	COG0492	ferredoxin-NADP+ reductase activity
FAI40_RS10270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FAI40_RS10285	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FAI40_RS10290	COG0416	fatty acid biosynthetic process
FAI40_RS10295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FAI40_RS10315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FAI40_RS10320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FAI40_RS10325	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FAI40_RS10330	COG2226	methyltransferase
FAI40_RS10335	COG0268	Binds directly to 16S ribosomal RNA
FAI40_RS10390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FAI40_RS10410	COG3657	addiction module killer protein
FAI40_RS10425	COG1192	Involved in chromosome partitioning