locus-tag	class	description
HN018_RS00005	ENOG4105CR4	methylisocitrate lyase
HN018_RS00010	ENOG4105BZN	citrate synthase
HN018_RS00035	ENOG4105KXX	peptidase s58 dmpa
HN018_RS00040	ENOG4105EB3	Histidine kinase
HN018_RS00045	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HN018_RS00050	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HN018_RS00055	ENOG4105CFG	Acts as a chaperone (By similarity)
HN018_RS00060	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HN018_RS00065	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HN018_RS00070	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HN018_RS00075	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HN018_RS00085	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_RS00090	ENOG4105DSF	transport protein
HN018_RS00140	ENOG4105EWU	Squalene--hopene cyclase
HN018_RS00145	ENOG4107S11	squalene-associated FAD-dependent desaturase
HN018_RS00150	ENOG4105FE1	phytoene synthase
HN018_RS00155	ENOG4105FBD	synthase
HN018_RS00180	ENOG4105CHR	reductase
HN018_RS00185	ENOG4105CHR	reductase
HN018_RS00190	ENOG4105CMG	Carbohydrate kinase
HN018_RS00195	ENOG4105CNN	ABC, transporter
HN018_RS00205	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS00210	ENOG4108Y83	glucose-6-phosphate isomerase
HN018_RS00215	ENOG4108UHU	Aldolase
HN018_RS00225	ENOG4108JQ1	Dehydrogenase
HN018_RS00230	ENOG4107T8T	UPF0173 metal-dependent hydrolase
HN018_RS00235	ENOG4106KNT	transcriptional regulator
HN018_RS00265	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
HN018_RS00270	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
HN018_RS00275	ENOG4105Z85	coenzyme PQQ synthesis
HN018_RS00280	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
HN018_RS00335	ENOG4108SHN	Glycosyl transferase, family 2
HN018_RS00350	ENOG4108JQB	penicillin-binding protein 1C
HN018_RS00365	ENOG4108ZZ3	UPF0260 protein
HN018_RS00380	ENOG4108IJ6	ABC transporter
HN018_RS00410	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HN018_RS00430	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HN018_RS00435	ENOG4105D7B	Flagellar biosynthesis protein flha
HN018_RS00440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN018_RS00445	ENOG4105DD5	Flagellar motor switch protein
HN018_RS00455	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HN018_RS00475	ENOG4105BZE	flagellar hook protein, FlgE
HN018_RS00510	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HN018_RS00550	ENOG4105M74	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HN018_RS00625	ENOG4105C3Q	Glycosyl transferase, family 2
HN018_RS00635	ENOG410609C	Acyl carrier protein
HN018_RS00665	ENOG4105D3Q	Sugar transferase
HN018_RS00675	ENOG4105K64	Glycosyl transferase, family 2
HN018_RS00700	ENOG4105BZU	Histidine kinase
HN018_RS00765	ENOG4108IJ6	ABC transporter
HN018_RS00770	ENOG4105DHQ	Histidine kinase
HN018_RS00775	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HN018_RS00820	ENOG4105ECM	Sensor protein basS pmrB
HN018_RS00825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS00855	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_RS00865	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN018_RS00880	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HN018_RS00885	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HN018_RS00925	ENOG4105C2J	ABC transporter
HN018_RS00930	ENOG4105CNN	ABC, transporter
HN018_RS00935	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS00945	ENOG4105CTU	Proline racemase
HN018_RS00950	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HN018_RS00960	ENOG4107QTZ	amino acid
HN018_RS00995	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_RS01015	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS01020	ENOG4105BZU	Histidine kinase
HN018_RS01030	ENOG4105C32	Amino acid ABC transporter (Permease)
HN018_RS01040	ENOG4105C0Z	ABC transporter
HN018_RS01045	ENOG4108IV0	ABC, transporter
HN018_RS01060	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_RS01085	ENOG4105CHR	reductase
HN018_RS01090	ENOG4105C87	Aminotransferase class I and II
HN018_RS01095	ENOG4105C3U	ABC transporter
HN018_RS01110	ENOG4105DKT	Transcriptional regulator
HN018_RS01125	ENOG4105E6M	Sulphatase-modifying factor protein
HN018_RS01135	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HN018_RS01140	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_RS01145	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HN018_RS01160	ENOG4105CDA	abc transporter atp-binding protein
HN018_RS01165	ENOG4105E5Q	amino acid AbC transporter
HN018_RS01180	ENOG4105E1J	oxidoreductase
HN018_RS01195	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_RS01205	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HN018_RS01210	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HN018_RS01215	ENOG4105KI2	Urea amidohydrolase subunit beta
HN018_RS01220	ENOG4105CQM	Urea amidohydrolase subunit alpha
HN018_RS01225	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HN018_RS01230	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HN018_RS01235	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HN018_RS01240	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
HN018_RS01245	ENOG4105CPQ	Dehydrogenase
HN018_RS01265	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HN018_RS01275	ENOG4105CHR	reductase
HN018_RS01295	ENOG4105CMT	Dihydroxyacetone kinase
HN018_RS01300	ENOG4107YVI	ribose 5-phosphate isomerase
HN018_RS01305	ENOG4105CP7	Triose-phosphate isomerase
HN018_RS01310	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HN018_RS01315	ENOG4105E39	Enoyl-CoA hydratase
HN018_RS01320	ENOG4107Z7P	Ferredoxin
HN018_RS01345	ENOG4108URH	decarboxylase
HN018_RS01355	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HN018_RS01360	ENOG4105CH6	catalase
HN018_RS01365	ENOG4105C5Q	Transcriptional regulator
HN018_RS01420	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
HN018_RS01425	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HN018_RS01440	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HN018_RS01450	ENOG4105CMR	udp-glucose 4-epimerase
HN018_RS01485	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HN018_RS01490	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HN018_RS01495	ENOG4105C2X	Arabinose 5-phosphate isomerase
HN018_RS01515	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
HN018_RS01525	ENOG410903C	(LipO)protein
HN018_RS01550	ENOG4105DTI	Phosphonopyruvate decarboxylase
HN018_RS01565	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HN018_RS01570	ENOG4105C5W	Aldolase
HN018_RS01580	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HN018_RS01600	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HN018_RS01605	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HN018_RS01625	ENOG4105EEQ	Na H antiporter
HN018_RS01635	ENOG4105CNN	ABC, transporter
HN018_RS01640	ENOG4105C2J	ABC transporter
HN018_RS01650	ENOG4105CPQ	Dehydrogenase
HN018_RS01655	ENOG4108UTZ	Dihydroxyacetone kinase
HN018_RS01660	ENOG4105CMT	Dihydroxyacetone kinase
HN018_RS01670	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HN018_RS01680	ENOG4108Z9K	Osmotically inducible protein
HN018_RS01685	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HN018_RS01700	ENOG4105CAU	Arsenical resistance protein, ArsH
HN018_RS01725	ENOG4107QRI	Phosphoketolase
HN018_RS01745	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HN018_RS01750	ENOG4105DQE	DNA ligase
HN018_RS01770	ENOG4108DT4	serine threonine protein kinase
HN018_RS01780	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HN018_RS01790	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HN018_RS01800	ENOG4105F7F	Chaperone
HN018_RS01815	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_RS01820	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HN018_RS01845	ENOG4107SC1	transglycosylase
HN018_RS01850	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN018_RS01870	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN018_RS01875	ENOG4105BZU	Histidine kinase
HN018_RS01900	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
HN018_RS01905	ENOG4108R6K	riboflavin synthase, subunit alpha
HN018_RS01910	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HN018_RS01915	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HN018_RS01920	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HN018_RS01935	ENOG4105BZU	Histidine kinase
HN018_RS01955	ENOG4107S2Z	UPF0761 membrane protein
HN018_RS02005	ENOG4105CZQ	inner membrane transport protein YdhC
HN018_RS02015	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HN018_RS02025	ENOG4107SZR	mannose-6-phosphate isomerase
HN018_RS02035	ENOG4105D06	uba thif-type nad fad binding protein
HN018_RS02050	ENOG4105CA9	Pyruvate kinase
HN018_RS02065	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HN018_RS02070	ENOG4105CYM	Glutathione S-transferase
HN018_RS02075	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HN018_RS02080	ENOG4105CAY	ferredoxin--nadp reductase
HN018_RS02090	ENOG4108S0S	Nucleotidyl transferase
HN018_RS02100	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HN018_RS02120	ENOG410901P	UPF0249 protein
HN018_RS02140	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HN018_RS02145	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN018_RS02155	ENOG4105DIQ	Transcriptional regulator
HN018_RS02160	ENOG4105C2J	ABC transporter
HN018_RS02170	ENOG4105CNN	ABC, transporter
HN018_RS02175	ENOG4105D4B	ABC, transporter
HN018_RS02180	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HN018_RS02195	ENOG4105ZXK	Dehydrogenase
HN018_RS02200	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HN018_RS02205	ENOG4105G63	Type III effector Hrp-dependent
HN018_RS02295	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HN018_RS02300	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HN018_RS02305	ENOG4107QM5	aconitate hydratase
HN018_RS02315	ENOG4105E5Q	amino acid AbC transporter
HN018_RS02320	ENOG4105K56	Transcriptional regulator
HN018_RS02325	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HN018_RS02330	ENOG4108MX3	Polysaccharide Biosynthesis Protein
HN018_RS02340	ENOG4105C26	Dehydrogenase
HN018_RS02350	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HN018_RS02355	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HN018_RS02375	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HN018_RS02390	ENOG4105DIA	mandelate racemase muconate lactonizing
HN018_RS02395	ENOG4105CHR	reductase
HN018_RS02400	ENOG4105C2J	ABC transporter
HN018_RS02405	ENOG4105CNN	ABC, transporter
HN018_RS02420	ENOG4105NWF	RbsD or FucU transport
HN018_RS02425	ENOG4105DGW	oligopeptidase A
HN018_RS02460	ENOG4105BZU	Histidine kinase
HN018_RS02465	ENOG4107S5I	aldo keto reductase
HN018_RS02470	ENOG4108JQC	penicillin-binding protein 1A
HN018_RS02510	ENOG4105E0F	Histidine kinase
HN018_RS02520	ENOG4107B2H	carbonic anhydrase
HN018_RS02525	ENOG4105CHH	sulfate transporter
HN018_RS02545	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
HN018_RS02570	ENOG41090R7	Ferric uptake
HN018_RS02580	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HN018_RS02585	ENOG4108WRK	Transcriptional regulator
HN018_RS02595	ENOG4105E33	succinate dehydrogenase
HN018_RS02600	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HN018_RS02610	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
HN018_RS02625	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HN018_RS02635	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HN018_RS02650	ENOG4105D6Z	AFG1 family ATPase
HN018_RS02655	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HN018_RS02660	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HN018_RS02665	ENOG4105C7S	Dehydrogenase
HN018_RS02670	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN018_RS02675	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HN018_RS02680	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HN018_RS02685	ENOG4105CPC	Aldo Keto reductase
HN018_RS02695	ENOG4105CSH	Transporter
HN018_RS02740	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS02755	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HN018_RS02775	ENOG4108WUH	Transcriptional regulator, TetR family
HN018_RS02785	ENOG4105F1S	paraquat-inducible protein a
HN018_RS02790	ENOG4105DY2	Paraquat-inducible protein b
HN018_RS02945	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_RS02955	ENOG4105C2J	ABC transporter
HN018_RS02960	ENOG4107SDZ	Galactoside transport system permease protein mglC
HN018_RS02965	ENOG4105CNN	ABC, transporter
HN018_RS02975	ENOG4108QDE	fad dependent oxidoreductase
HN018_RS02985	ENOG4105D7W	serine acetyltransferase
HN018_RS02995	ENOG4108YZA	Nitrogen regulatory protein pii
HN018_RS03000	ENOG4105BZU	Histidine kinase
HN018_RS03010	ENOG4105D05	Receptor
HN018_RS03020	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_RS03030	ENOG4105C25	Primosomal protein n'
HN018_RS03045	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HN018_RS03055	ENOG4107RE3	peptidase, S41
HN018_RS03070	ENOG4108VAC	response regulator
HN018_RS03075	ENOG4108HRK	Histidine kinase
HN018_RS03085	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HN018_RS03095	ENOG4105DE4	1-phosphofructokinase
HN018_RS03105	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HN018_RS03110	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HN018_RS03115	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HN018_RS03120	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HN018_RS03125	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HN018_RS03135	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HN018_RS03145	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HN018_RS03150	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HN018_RS03160	ENOG4105CPC	Aldo Keto reductase
HN018_RS03195	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HN018_RS03245	ENOG4105C5X	domain protein
HN018_RS03260	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HN018_RS03330	ENOG4105FXM	Copper resistance protein
HN018_RS03350	ENOG4105E3B	Multicopper oxidase
HN018_RS03385	ENOG4105RQF	LysR family Transcriptional regulator
HN018_RS03390	ENOG4105CD3	dihydroorotase
HN018_RS03410	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_RS03415	ENOG4105C3U	ABC transporter
HN018_RS03420	ENOG4108JQ7	(ABC) transporter
HN018_RS03425	ENOG4105E1J	oxidoreductase
HN018_RS03430	ENOG4105MP9	class II Aldolase
HN018_RS03435	ENOG4105GAV	receptor
HN018_RS03455	ENOG4105C5I	Dehydrogenase
HN018_RS03470	ENOG4108BUD	transposase
HN018_RS03505	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HN018_RS03510	ENOG4105E98	transcriptional regulator DeoR family
HN018_RS03515	ENOG4105DEF	Extracellular solute-binding protein, family 5
HN018_RS03525	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_RS03530	ENOG4105C3U	ABC transporter
HN018_RS03535	ENOG4108JQ7	(ABC) transporter
HN018_RS03545	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HN018_RS03555	ENOG4107ZSV	Receptor
HN018_RS03560	ENOG4105F38	ABC transporter, permease
HN018_RS03565	ENOG4105D38	putrescine abc transporter
HN018_RS03570	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN018_RS03605	ENOG4105ETX	regulatoR
HN018_RS03625	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HN018_RS03630	ENOG4105HMI	Membrane
HN018_RS03635	ENOG4105DUM	transcriptional regulator, lysR family
HN018_RS03700	ENOG4105BZU	Histidine kinase
HN018_RS03715	ENOG4105E0X	reductase
HN018_RS03720	ENOG4105NCT	RNA Polymerase
HN018_RS03735	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HN018_RS03760	ENOG4105F5W	AtP-binding protein
HN018_RS03770	ENOG4108KSA	LysR family transcriptional regulator
HN018_RS03775	ENOG4105EEQ	Na H antiporter
HN018_RS03785	ENOG41082A2	Alpha beta hydrolase
HN018_RS03800	ENOG4108KBJ	Inner membrane protein YkgB
HN018_RS03830	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_RS03840	ENOG4105F9F	transposase
HN018_RS03880	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HN018_RS03890	ENOG4108KDQ	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity)
HN018_RS03900	ENOG4105CR8	Transcriptional regulator
HN018_RS03905	ENOG4105F9F	transposase
HN018_RS03915	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_RS03920	ENOG4105F9F	transposase
HN018_RS03925	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_RS03935	ENOG4105C3U	ABC transporter
HN018_RS03945	ENOG4105CK5	oxidoreductase
HN018_RS03960	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_RS03975	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HN018_RS04025	ENOG4105F9F	transposase
HN018_RS04045	ENOG4105CHM	Aminotransferase
HN018_RS04075	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HN018_RS04080	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HN018_RS04105	ENOG4105EJC	lysr family transcriptional regulator
HN018_RS04110	ENOG4105EXG	Transcriptional regulator
HN018_RS04125	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HN018_RS04130	ENOG4105CHU	acetyl-coa acetyltransferase
HN018_RS04135	ENOG4107QNJ	CoA-transferase subunit B
HN018_RS04145	ENOG4107HP6	Transcriptional regulator
HN018_RS04150	ENOG4105CHR	reductase
HN018_RS04170	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HN018_RS04185	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS04190	ENOG4105C2J	ABC transporter
HN018_RS04195	ENOG4105CNN	ABC, transporter
HN018_RS04200	ENOG4107R9N	ABC transporter
HN018_RS04205	ENOG4105CHR	reductase
HN018_RS04215	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HN018_RS04225	ENOG4105CHR	reductase
HN018_RS04235	ENOG4105C2J	ABC transporter
HN018_RS04240	ENOG4105CNN	ABC, transporter
HN018_RS04245	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
HN018_RS04250	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HN018_RS04255	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_RS04285	ENOG4108RXX	maleylacetoacetate isomerase
HN018_RS04295	ENOG4108WYP	Transcriptional regulator
HN018_RS04300	ENOG4105CHR	reductase
HN018_RS04325	ENOG4108Z0R	Transferase
HN018_RS04330	ENOG4105CHU	acetyl-coa acetyltransferase
HN018_RS04365	ENOG4105C2J	ABC transporter
HN018_RS04370	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS04380	ENOG4105CPQ	Dehydrogenase
HN018_RS04395	ENOG4108RVA	ribokinase
HN018_RS04400	ENOG4108UHU	Aldolase
HN018_RS04475	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HN018_RS04490	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HN018_RS04495	ENOG4108IND	Tetr family transcriptional regulator
HN018_RS04520	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HN018_RS04525	ENOG4105CHR	reductase
HN018_RS04530	ENOG4105KVH	Transcriptional regulator
HN018_RS04535	ENOG4105DJB	Major Facilitator Superfamily
HN018_RS04550	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
HN018_RS04555	ENOG4105CHF	Glutathione S-transferase
HN018_RS04560	ENOG4105F4R	Transcriptional regulator mode
HN018_RS04575	ENOG4105D2S	major facilitator superfamily
HN018_RS04590	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HN018_RS04605	ENOG4108UJU	UPF0301 protein
HN018_RS04615	ENOG4105EMU	Dehydrogenase
HN018_RS04620	ENOG4105CSR	polyphosphate kinase 2
HN018_RS04650	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HN018_RS04655	ENOG4105DZ1	carboxypeptidase
HN018_RS04660	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HN018_RS04670	ENOG4108ZCF	integral membrane protein
HN018_RS04685	ENOG4107QPR	SAICAR synthetase
HN018_RS04700	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HN018_RS04705	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HN018_RS04715	ENOG4105M2J	Glutaredoxin
HN018_RS04725	ENOG41082FP	UPF0102 protein
HN018_RS04730	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN018_RS04740	ENOG4105IPI	Membrane
HN018_RS04750	ENOG4105KHC	sulfurtransferase
HN018_RS04755	ENOG4105C28	cystathionine
HN018_RS04770	ENOG4105C0P	Mg chelatase subunit ChlI
HN018_RS04775	ENOG4108JQ1	Dehydrogenase
HN018_RS04780	ENOG4105KVH	Transcriptional regulator
HN018_RS04795	ENOG4105G9V	cytochrome C
HN018_RS04810	ENOG4105E0K	tonB-dependent siderophore receptor
HN018_RS04815	ENOG4105E09	nadh pyrophosphatase
HN018_RS04825	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HN018_RS04830	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HN018_RS04835	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HN018_RS04845	ENOG4105KRF	dihydroneopterin aldolase
HN018_RS04850	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN018_RS04855	ENOG4105WEF	catalase
HN018_RS04860	ENOG4108N8X	transition metal ion binding
HN018_RS04875	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HN018_RS04880	ENOG4105CAT	Cytidine monophosphate kinase
HN018_RS04885	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HN018_RS04910	ENOG4105KWW	Biogenesis protein
HN018_RS04915	ENOG4107QX9	Thiol disulfide interChange protein
HN018_RS04920	ENOG4105DA4	cytochrome c-type biogenesis protein
HN018_RS04925	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HN018_RS04935	ENOG41060IM	Heme exporter protein
HN018_RS04970	ENOG4105C5I	Dehydrogenase
HN018_RS04975	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HN018_RS04990	ENOG4105F0F	Oxalate decarboxylase
HN018_RS04995	ENOG4105CR8	Transcriptional regulator
HN018_RS05005	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN018_RS05010	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HN018_RS05040	ENOG4105CHR	reductase
HN018_RS05065	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS05070	ENOG4105EB3	Histidine kinase
HN018_RS05095	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_RS05115	ENOG4105CMT	Dihydroxyacetone kinase
HN018_RS05120	ENOG4105C2J	ABC transporter
HN018_RS05125	ENOG4105CNN	ABC, transporter
HN018_RS05130	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS05135	ENOG4105MVE	transcriptional regulator
HN018_RS05140	ENOG4105CHR	reductase
HN018_RS05150	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HN018_RS05155	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HN018_RS05160	ENOG4108VZM	50s ribosomal protein L10
HN018_RS05165	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HN018_RS05170	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN018_RS05175	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN018_RS05180	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HN018_RS05185	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HN018_RS05190	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HN018_RS05195	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HN018_RS05200	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HN018_RS05205	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HN018_RS05210	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HN018_RS05215	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HN018_RS05220	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HN018_RS05225	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HN018_RS05230	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HN018_RS05235	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HN018_RS05240	ENOG41083MP	50s ribosomal protein l29
HN018_RS05245	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HN018_RS05250	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HN018_RS05255	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HN018_RS05260	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HN018_RS05265	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HN018_RS05270	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HN018_RS05275	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HN018_RS05280	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HN018_RS05285	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HN018_RS05290	ENOG41084HQ	50S ribosomal protein L30
HN018_RS05295	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HN018_RS05300	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HN018_RS05305	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HN018_RS05310	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HN018_RS05315	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HN018_RS05320	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN018_RS05325	ENOG4108ZT0	50S ribosomal protein l17
HN018_RS05335	ENOG4107QJR	hflk protein
HN018_RS05355	ENOG4107FSV	UPF0391 membrane protein
HN018_RS05375	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
HN018_RS05385	ENOG4105C8M	UPF0272 protein
HN018_RS05400	ENOG4105CV8	reductase
HN018_RS05415	ENOG4105BZS	acriflavin resistance protein
HN018_RS05420	ENOG4105BZS	acriflavin resistance protein
HN018_RS05425	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HN018_RS05440	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HN018_RS05445	ENOG4105CEC	DNA methylase N-4 N-6
HN018_RS05465	ENOG4105KAV	tspo and mbr like protein
HN018_RS05485	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HN018_RS05520	ENOG4105DU0	nucleoside hydrolase
HN018_RS05525	ENOG4105BZ1	(ABC) transporter
HN018_RS05540	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_RS05550	ENOG4108IXY	short-chain dehydrogenase reductase
HN018_RS05555	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HN018_RS05560	ENOG4107S2Z	UPF0761 membrane protein
HN018_RS05570	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HN018_RS05580	ENOG4105CN1	protease
HN018_RS05590	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HN018_RS05600	ENOG4105E0X	reductase
HN018_RS05615	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HN018_RS05635	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HN018_RS05650	ENOG4105C7B	Threonine dehydratase
HN018_RS05655	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HN018_RS05660	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HN018_RS05670	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HN018_RS05680	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HN018_RS05685	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HN018_RS05735	ENOG4105CYM	Glutathione S-transferase
HN018_RS05740	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HN018_RS05745	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HN018_RS05750	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HN018_RS05755	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HN018_RS05760	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HN018_RS05770	ENOG4107U2T	alpha beta
HN018_RS05790	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HN018_RS05795	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HN018_RS05815	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN018_RS05825	ENOG4105QVC	MOSC domain-containing protein
HN018_RS05840	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HN018_RS05845	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HN018_RS05850	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HN018_RS05875	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HN018_RS05880	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HN018_RS05885	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HN018_RS05890	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
HN018_RS05980	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HN018_RS05990	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HN018_RS06005	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HN018_RS06015	ENOG4106TD9	Diguanylate cyclase
HN018_RS06040	ENOG4105CV8	reductase
HN018_RS06065	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS06070	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS06075	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HN018_RS06080	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HN018_RS06090	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HN018_RS06105	ENOG4105DQ4	alcohol dehydrogenase
HN018_RS06110	ENOG4108NVM	synthesis repressor PhaR
HN018_RS06115	ENOG4107E2E	PKHD-type hydroxylase
HN018_RS06120	ENOG4108ESX	Receptor
HN018_RS06130	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HN018_RS06135	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HN018_RS06185	ENOG4105MVE	transcriptional regulator
HN018_RS06190	ENOG4106UW1	Major Facilitator superfamily
HN018_RS06215	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_RS06230	ENOG4105BZU	Histidine kinase
HN018_RS06235	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS06240	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HN018_RS06245	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HN018_RS06250	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_RS06255	ENOG4105CW7	secretion protein, HlyD family
HN018_RS06270	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HN018_RS06285	ENOG410856B	UPF0235 protein
HN018_RS06290	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HN018_RS06300	ENOG41090U3	tautomerase
HN018_RS06315	ENOG4107WI4	Aldose-1-epimerase
HN018_RS06325	ENOG4108RRZ	Transcription elongation factor GreB
HN018_RS06330	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HN018_RS06350	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_RS06355	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HN018_RS06370	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HN018_RS06380	ENOG4105D98	threonine synthase
HN018_RS06390	ENOG4105CTD	carboxy-peptidase
HN018_RS06400	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HN018_RS06405	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HN018_RS06415	ENOG4105CHR	reductase
HN018_RS06420	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HN018_RS06440	ENOG4105CPN	adenine deaminase
HN018_RS06490	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HN018_RS06515	ENOG4105CRQ	synthase (Component I)
HN018_RS06520	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HN018_RS06525	ENOG4105BZU	Histidine kinase
HN018_RS06530	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HN018_RS06535	ENOG4108VYJ	response regulator receiver protein
HN018_RS06555	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN018_RS06570	ENOG4105MJ2	Competence protein
HN018_RS06575	ENOG4105VW4	glutaredoxin 3
HN018_RS06595	ENOG4105CFH	Aspartokinase
HN018_RS06610	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HN018_RS06615	ENOG4105CUT	histidyl-tRNA synthetase
HN018_RS06620	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HN018_RS06640	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HN018_RS06660	ENOG4106VZX	establishment of viral latency
HN018_RS06745	ENOG4105Y2X	UPF0335 protein
HN018_RS06795	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_RS06830	ENOG4105CAR	Terminase, large subunit
HN018_RS06980	ENOG4105FAT	Acyl-transferase
HN018_RS07035	ENOG4105C37	(CBS) domain
HN018_RS07045	ENOG4108RAV	Conserved protein
HN018_RS07065	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HN018_RS07070	ENOG4105DC7	peptidase M24
HN018_RS07080	ENOG4108Z7F	N-acetyltransferase
HN018_RS07085	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HN018_RS07090	ENOG4105C4R	Atp-dependent dna helicase
HN018_RS07095	ENOG4105W5Q	DNA repair protein (RadC
HN018_RS07100	ENOG4105BZU	Histidine kinase
HN018_RS07105	ENOG4108Y50	Glutathione-dependent formaldehyde-activating Gfa
HN018_RS07120	ENOG4107QZ7	Cellulose synthase catalytic subunit
HN018_RS07125	ENOG4105D1F	ATP-binding protein
HN018_RS07135	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HN018_RS07145	ENOG4105W5Q	DNA repair protein (RadC
HN018_RS07150	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HN018_RS07155	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HN018_RS07180	ENOG41082FS	50S ribosomal protein L31
HN018_RS07190	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HN018_RS07195	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HN018_RS07210	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HN018_RS07215	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HN018_RS07220	ENOG4107TYG	Oxidoreductase domain-containing protein
HN018_RS07230	ENOG4107SQD	Transcriptional regulator, GntR family
HN018_RS07260	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_RS07270	ENOG4105H3G	oxidoreductase
HN018_RS07280	ENOG4105C5H	ABC transporter
HN018_RS07290	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HN018_RS07295	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HN018_RS07305	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HN018_RS07310	ENOG41074H6	response regulator
HN018_RS07335	ENOG4108JJ9	ABC, transporter
HN018_RS07340	ENOG4108JJ8	(ABC) transporter
HN018_RS07350	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN018_RS07355	ENOG4107S5I	aldo keto reductase
HN018_RS07360	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_RS07370	ENOG4105E98	transcriptional regulator DeoR family
HN018_RS07375	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HN018_RS07380	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN018_RS07385	ENOG4108IJ9	(ABC) transporter
HN018_RS07395	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
HN018_RS07410	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HN018_RS07435	ENOG4105E0F	Histidine kinase
HN018_RS07445	ENOG410903C	(LipO)protein
HN018_RS07460	ENOG4105C2J	ABC transporter
HN018_RS07465	ENOG4105CNN	ABC, transporter
HN018_RS07470	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HN018_RS07475	ENOG4107XZX	Involved in the transcription termination process (By similarity)
HN018_RS07480	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HN018_RS07520	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HN018_RS07535	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HN018_RS07540	ENOG4105C01	Dihydroxy-acid dehydratase
HN018_RS07570	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HN018_RS07575	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HN018_RS07580	ENOG4105C7W	Xanthine dehydrogenase
HN018_RS07590	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
HN018_RS07600	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HN018_RS07605	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HN018_RS07615	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HN018_RS07630	ENOG4105C2J	ABC transporter
HN018_RS07650	ENOG4108RTU	Aldolase
HN018_RS07655	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
HN018_RS07660	ENOG4107EJG	GntR family transcriptional regulator
HN018_RS07675	ENOG41082W1	Cupin 2, conserved barrel domain protein
HN018_RS07685	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_RS07690	ENOG4105BZ1	(ABC) transporter
HN018_RS07695	ENOG4108WYP	Transcriptional regulator
HN018_RS07700	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HN018_RS07705	ENOG4107QMS	site-determining protein
HN018_RS07710	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HN018_RS07720	ENOG4105CBX	hi0933 family
HN018_RS07735	ENOG4107SRH	Nad-dependent epimerase dehydratase
HN018_RS07755	ENOG4105S64	Formate nitrite transporter
HN018_RS07795	ENOG4105C22	threonyL-tRNA synthetase
HN018_RS07800	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HN018_RS07820	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HN018_RS07835	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HN018_RS07840	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HN018_RS07845	ENOG4105K4P	CoA-binding domain protein
HN018_RS07860	ENOG4107B2H	carbonic anhydrase
HN018_RS07865	ENOG4105BZU	Histidine kinase
HN018_RS07875	ENOG4105CQZ	Histidine kinase
HN018_RS07885	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HN018_RS07890	ENOG4105BZU	Histidine kinase
HN018_RS07900	ENOG4108IYU	L-aspartate oxidase
HN018_RS07905	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HN018_RS07910	ENOG4105BZP	glycoside hydrolase 15-related
HN018_RS07925	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HN018_RS07965	ENOG4105D49	3-dehydroquinate synthase
HN018_RS07975	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_RS07980	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HN018_RS08000	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
HN018_RS08010	ENOG4105CPC	Aldo Keto reductase
HN018_RS08015	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS08045	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HN018_RS08050	ENOG4105C08	Histidine kinase
HN018_RS08055	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HN018_RS08060	ENOG4107SFI	Major Facilitator superfamily
HN018_RS08065	ENOG4105D3W	isochorismatase
HN018_RS08075	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HN018_RS08085	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HN018_RS08090	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HN018_RS08095	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HN018_RS08105	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HN018_RS08110	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HN018_RS08115	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HN018_RS08120	ENOG4105M6F	mutator MutT protein
HN018_RS08130	ENOG4105VK3	rdd domain containing protein
HN018_RS08135	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HN018_RS08140	ENOG4107TF3	peptidylprolyl cis-trans isomerase
HN018_RS08145	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HN018_RS08150	ENOG4105CDY	transcriptional regulatory protein
HN018_RS08155	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HN018_RS08170	ENOG4105F9F	transposase
HN018_RS08180	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS08185	ENOG4105CR8	Transcriptional regulator
HN018_RS08200	ENOG4105F9E	Shikimate 5-dehydrogenase
HN018_RS08230	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HN018_RS08235	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HN018_RS08240	ENOG4107YD3	Thioesterase
HN018_RS08245	ENOG4105E02	MotA TolQ exbB proton channel
HN018_RS08250	ENOG4108ZZF	transport protein (ExbD)
HN018_RS08260	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HN018_RS08265	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HN018_RS08275	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HN018_RS08285	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_RS08295	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HN018_RS08300	ENOG4105DWF	phosphomethylpyrimidine kinase
HN018_RS08310	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HN018_RS08315	ENOG4105D3R	alkyl hydroperoxide reductase
HN018_RS08325	ENOG4105YK5	50S ribosomal protein L36
HN018_RS08335	ENOG4106VK6	Flagellar motor protein
HN018_RS08350	ENOG4105ECY	inositol monophosphatase
HN018_RS08355	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HN018_RS08380	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HN018_RS08405	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HN018_RS08410	ENOG4105D48	metallophosphoesterase
HN018_RS08425	ENOG4105E2A	Dehydrogenase
HN018_RS08430	ENOG4105FYV	Amp nucleosidase
HN018_RS08435	ENOG4105EEQ	Na H antiporter
HN018_RS08450	ENOG4108IND	Tetr family transcriptional regulator
HN018_RS08465	ENOG4105CHR	reductase
HN018_RS08470	ENOG4105CPQ	Dehydrogenase
HN018_RS08475	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HN018_RS08480	ENOG4108UYE	Lactoylglutathione lyase
HN018_RS08510	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HN018_RS08530	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HN018_RS08535	ENOG4107SZR	mannose-6-phosphate isomerase
HN018_RS08545	ENOG4107S6X	Glycosyl transferase, family 2
HN018_RS08560	ENOG4105C5F	glutamine synthetase
HN018_RS08565	ENOG4108YZA	Nitrogen regulatory protein pii
HN018_RS08570	ENOG4105CHM	Aminotransferase
HN018_RS08580	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HN018_RS08590	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HN018_RS08595	ENOG4108UJD	30S ribosomal protein S9
HN018_RS08600	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HN018_RS08610	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HN018_RS08615	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HN018_RS08625	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HN018_RS08635	ENOG4105CHM	Aminotransferase
HN018_RS08640	ENOG4105D6E	homoserine dehydrogenase
HN018_RS08645	ENOG4105CBT	Fructose-1,6-bisphosphatase
HN018_RS08650	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HN018_RS08675	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_RS08700	ENOG4105EG2	ABC transporter, permease
HN018_RS08725	ENOG4105CGN	Glycosyl transferase (Group 1
HN018_RS08790	ENOG4108UT2	hemolysin iii
HN018_RS08825	ENOG4105BZU	Histidine kinase
HN018_RS08830	ENOG4105CB5	ATP-dependent DNA helicase recG
HN018_RS08835	ENOG4107NKQ	Flavinator of succinate dehydrogenase
HN018_RS08845	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HN018_RS08880	ENOG4105DHU	Bile acid
HN018_RS08885	ENOG4105D05	Receptor
HN018_RS08910	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HN018_RS08920	ENOG4105CNN	ABC, transporter
HN018_RS08925	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS08990	ENOG4105EY8	ABC transporter
HN018_RS08995	ENOG4108RDB	capsule polysaccharide export inner-membrane protein
HN018_RS09025	ENOG41084CK	capsule polysaccharide
HN018_RS09045	ENOG4105CUB	amino acid
HN018_RS09075	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HN018_RS09080	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HN018_RS09085	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HN018_RS09090	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HN018_RS09095	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HN018_RS09100	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HN018_RS09110	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HN018_RS09145	ENOG4105C4R	Atp-dependent dna helicase
HN018_RS09150	ENOG4105CEV	competence damage-inducible protein
HN018_RS09160	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS09165	ENOG4105C2J	ABC transporter
HN018_RS09170	ENOG4105CNN	ABC, transporter
HN018_RS09175	ENOG4105CNN	ABC, transporter
HN018_RS09190	ENOG4105CHR	reductase
HN018_RS09195	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_RS09220	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN018_RS09245	ENOG4105DEN	Luciferase family
HN018_RS09255	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_RS09295	ENOG4105CNN	ABC, transporter
HN018_RS09300	ENOG4105C2J	ABC transporter
HN018_RS09310	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HN018_RS09335	ENOG4105CHR	reductase
HN018_RS09340	ENOG4106N3A	copper homeostasis protein cutc
HN018_RS09345	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HN018_RS09395	ENOG4105EMN	RNA polymerase sigma factor
HN018_RS09405	ENOG4107Z3H	Transcriptional regulator, TetR family
HN018_RS09410	ENOG4105CHR	reductase
HN018_RS09435	ENOG4105CHU	acetyl-coa acetyltransferase
HN018_RS09440	ENOG41079KZ	Major Facilitator Superfamily
HN018_RS09470	ENOG4108REK	sugar kinase
HN018_RS09485	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_RS09490	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HN018_RS09520	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HN018_RS09550	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HN018_RS09580	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HN018_RS09590	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HN018_RS09600	ENOG4105M00	molybdopterin converting factor, subunit 1
HN018_RS09605	ENOG4108ZAF	Molybdopterin
HN018_RS09615	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN018_RS09625	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HN018_RS09630	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HN018_RS09635	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HN018_RS09640	ENOG4105W0E	50S ribosomal protein L33
HN018_RS09655	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HN018_RS09665	ENOG4105EBR	Carboxylesterase
HN018_RS09675	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HN018_RS09680	ENOG4105EIG	urea carboxylase-associated protein 1
HN018_RS09690	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HN018_RS09700	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HN018_RS09715	ENOG4105CP7	Triose-phosphate isomerase
HN018_RS09725	ENOG4105CRQ	synthase (Component I)
HN018_RS09730	ENOG4105DDQ	anthranilate synthase
HN018_RS09735	ENOG4107QYG	anthranilate phosphoribosyltransferase
HN018_RS09740	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HN018_RS09745	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN018_RS09750	ENOG4108JYK	Dehydrogenase
HN018_RS09755	ENOG4105CPP	Dehydrogenase, E1 component
HN018_RS09760	ENOG4105C7S	Dehydrogenase
HN018_RS09765	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN018_RS09770	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HN018_RS09775	ENOG4108Z1B	Cyclase dehydrase
HN018_RS09790	ENOG4105CEV	competence damage-inducible protein
HN018_RS09795	ENOG4108ZAI	phosphatidylglycerophosphatase a
HN018_RS09805	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HN018_RS09810	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HN018_RS09815	ENOG4105CFG	Acts as a chaperone (By similarity)
HN018_RS09820	ENOG4105E50	uracil-dna glycosylase
HN018_RS09835	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS09845	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HN018_RS09855	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HN018_RS09860	ENOG4105C3F	Signal peptidase i
HN018_RS09865	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HN018_RS09875	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HN018_RS09880	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HN018_RS09885	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HN018_RS09895	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HN018_RS09900	ENOG4105DZP	Membrane-associated zinc metalloprotease
HN018_RS09905	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HN018_RS09915	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_RS09920	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HN018_RS09925	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_RS09935	ENOG4108UYE	Lactoylglutathione lyase
HN018_RS09945	ENOG4105VG0	50S ribosomal protein l34
HN018_RS09950	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HN018_RS09960	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HN018_RS09965	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HN018_RS09970	ENOG4105CAS	nag kinase
HN018_RS09980	ENOG4105BZU	Histidine kinase
HN018_RS09985	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HN018_RS09990	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HN018_RS10000	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HN018_RS10005	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HN018_RS10010	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HN018_RS10015	ENOG4108ZNX	Heat shock protein
HN018_RS10025	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
HN018_RS10030	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HN018_RS10035	ENOG4108IUZ	ABC transporter
HN018_RS10085	ENOG4105CJ3	phosphate transporter
HN018_RS10105	ENOG4107EJG	GntR family transcriptional regulator
HN018_RS10110	ENOG41062B0	ABC transporter, permease
HN018_RS10115	ENOG4107R9N	ABC transporter
HN018_RS10120	ENOG4105C2J	ABC transporter
HN018_RS10125	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
HN018_RS10135	ENOG4105CGK	Exodeoxyribonuclease III
HN018_RS10140	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HN018_RS10145	ENOG4105C75	arginyL-tRNA synthetase
HN018_RS10160	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HN018_RS10165	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HN018_RS10170	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HN018_RS10175	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HN018_RS10180	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HN018_RS10205	ENOG4105VIE	preprotein translocase, subunit YajC
HN018_RS10210	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HN018_RS10220	ENOG4105CHR	reductase
HN018_RS10240	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HN018_RS10245	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HN018_RS10250	ENOG4108UUM	single-stranded DNA-binding protein
HN018_RS10255	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN018_RS10260	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HN018_RS10285	ENOG4105D3R	alkyl hydroperoxide reductase
HN018_RS10300	ENOG4107QPB	Beta-lactamase domain protein
HN018_RS10310	ENOG4105EY8	ABC transporter
HN018_RS10335	ENOG4108Z03	MAF-like protein
HN018_RS10340	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HN018_RS10345	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HN018_RS10350	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HN018_RS10355	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HN018_RS10360	ENOG4105DHP	deoxycytidine triphosphate deaminase
HN018_RS10380	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HN018_RS10420	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_RS10445	ENOG4105CPQ	Dehydrogenase
HN018_RS10450	ENOG4105CHR	reductase
HN018_RS10455	ENOG4105C5I	Dehydrogenase
HN018_RS10465	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS10470	ENOG4105C8S	subunit m
HN018_RS10475	ENOG4105D65	subunit l
HN018_RS10480	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS10485	ENOG4107UFS	subunit j
HN018_RS10490	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS10495	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HN018_RS10500	ENOG4108IEH	NADH dehydrogenase subunit g
HN018_RS10505	ENOG4107QIZ	NADH dehydrogenase
HN018_RS10510	ENOG4105GKE	subunit e
HN018_RS10515	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS10520	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS10525	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HN018_RS10555	ENOG4105D1H	recombination factor protein RarA
HN018_RS10560	ENOG4105EI2	Pseudouridine synthase
HN018_RS10570	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
HN018_RS10585	ENOG4108J2P	Alpha beta hydrolase fold
HN018_RS10590	ENOG4105EJC	lysr family transcriptional regulator
HN018_RS10595	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HN018_RS10610	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HN018_RS10635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN018_RS10640	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HN018_RS10645	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HN018_RS10650	ENOG4105DXN	mazG family
HN018_RS10665	ENOG4105ED1	spovr family
HN018_RS10670	ENOG4106AKX	UPF0229 protein
HN018_RS10675	ENOG4105CYN	Serine protein kinase
HN018_RS10680	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HN018_RS10685	ENOG4105F8V	Hydrolase, tatD family
HN018_RS10700	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HN018_RS10705	ENOG4105DZ1	carboxypeptidase
HN018_RS10710	ENOG4105K6T	rare lipoprotein A
HN018_RS10715	ENOG4105CVE	Lytic murein transglycosylase
HN018_RS10745	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HN018_RS10900	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HN018_RS10905	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HN018_RS10910	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HN018_RS10915	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HN018_RS10940	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HN018_RS10975	ENOG4105C1J	atp-dependent rna helicase
HN018_RS10990	ENOG4105CWC	Acetylornithine deacetylase
HN018_RS11000	ENOG4105CUB	amino acid
HN018_RS11005	ENOG4105D52	delta-aminolevulinic acid dehydratase
HN018_RS11010	ENOG4105CUJ	penicillin amidase
HN018_RS11015	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HN018_RS11020	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN018_RS11025	ENOG4108I5G	Major Facilitator superfamily
HN018_RS11030	ENOG4106KE4	Dehydrogenase
HN018_RS11035	ENOG4107R5B	glutamine synthetase
HN018_RS11045	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
HN018_RS11050	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HN018_RS11055	ENOG4105CE9	30S ribosomal protein S2
HN018_RS11060	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_RS11065	ENOG4108IXY	short-chain dehydrogenase reductase
HN018_RS11080	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HN018_RS11090	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HN018_RS11100	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HN018_RS11105	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HN018_RS11110	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS11115	ENOG4105D65	subunit l
HN018_RS11120	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS11125	ENOG4105DF2	NADH dehydrogenase subunit j
HN018_RS11130	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS11135	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HN018_RS11140	ENOG4108IEH	NADH dehydrogenase subunit g
HN018_RS11145	ENOG4107QIZ	NADH dehydrogenase
HN018_RS11155	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS11160	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HN018_RS11165	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_RS11170	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HN018_RS11190	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HN018_RS11195	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HN018_RS11200	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HN018_RS11205	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HN018_RS11215	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HN018_RS11225	ENOG4105BZP	glycoside hydrolase 15-related
HN018_RS11230	ENOG4105C1J	atp-dependent rna helicase
HN018_RS11240	ENOG4105T0Z	Conserved Protein
HN018_RS11250	ENOG4105VG1	fes assembly suf system protein
HN018_RS11260	ENOG4105C9B	Cysteine desulfurase
HN018_RS11265	ENOG4105JRK	feS assembly protein SufD
HN018_RS11270	ENOG4105C3K	feS assembly ATPase SufC
HN018_RS11285	ENOG4106BRA	Membrane
HN018_RS11295	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HN018_RS11305	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HN018_RS11310	ENOG4105KDC	50s ribosomal protein l28
HN018_RS11320	ENOG4108JJ7	ABC transporter
HN018_RS11350	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
HN018_RS11360	ENOG4107ENK	receptor
HN018_RS11365	ENOG4105D94	Major Facilitator Superfamily
HN018_RS11390	ENOG4107SCA	Formamidase (EC 3.5.1.49)
HN018_RS11400	ENOG4105IPI	Membrane
HN018_RS11410	ENOG4105WJX	transcriptional regulator MERR family
HN018_RS11415	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HN018_RS11420	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN018_RS11425	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HN018_RS11430	ENOG41082R8	50S ribosomal protein l32
HN018_RS11445	ENOG4105E0F	Histidine kinase
HN018_RS11450	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HN018_RS11455	ENOG41090HR	transcriptional regulator
HN018_RS11460	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HN018_RS11470	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HN018_RS11475	ENOG4105K5G	30S ribosomal protein S21
HN018_RS11485	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HN018_RS11490	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HN018_RS11495	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HN018_RS11500	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HN018_RS11505	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HN018_RS11510	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HN018_RS11515	ENOG4105K5M	30s ribosomal protein S16
HN018_RS11535	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HN018_RS11540	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HN018_RS11570	ENOG4105F27	Major Facilitator
HN018_RS11580	ENOG4105CD3	dihydroorotase
HN018_RS11585	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HN018_RS11590	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_RS11600	ENOG4108KK1	membrane protein AbrB duplication
HN018_RS11605	ENOG4105D3W	isochorismatase
HN018_RS11610	ENOG4108RZE	Tetr family transcriptional regulator
HN018_RS11620	ENOG4107TYR	Glycosyl Transferase
HN018_RS11635	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HN018_RS11640	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_RS11715	ENOG4105RK9	auxin efflux carrier
HN018_RS11730	ENOG4105EEQ	Na H antiporter
HN018_RS11750	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HN018_RS11770	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HN018_RS11775	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HN018_RS11780	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HN018_RS11790	ENOG4105BZU	Histidine kinase
HN018_RS11795	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HN018_RS11810	ENOG4105C09	Bile acid
HN018_RS11815	ENOG4105DGU	Histone deacetylase
HN018_RS11835	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HN018_RS11890	ENOG4106VK6	Flagellar motor protein
HN018_RS11910	ENOG4105CS6	Rhs element vgr protein
HN018_RS11975	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HN018_RS11990	ENOG4105HFZ	Membrane
HN018_RS11995	ENOG4105M7V	2'-5' rna ligase
HN018_RS12005	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HN018_RS12010	ENOG4108RG0	uracil-dna glycosylase
HN018_RS12035	ENOG4105CHR	reductase
HN018_RS12040	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_RS12055	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HN018_RS12070	ENOG4105C7W	Xanthine dehydrogenase
HN018_RS12075	ENOG4108ZFD	Antibiotic biosynthesis monooxygenase
HN018_RS12080	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HN018_RS12105	ENOG4105CHR	reductase
HN018_RS12120	ENOG4105EW9	transcriptional regulator AsnC family
HN018_RS12135	ENOG4105DK7	lysyl-tRNA synthetase
HN018_RS12140	ENOG4105DVT	helicase
HN018_RS12145	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
HN018_RS12155	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HN018_RS12160	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HN018_RS12165	ENOG4105P0T	Usg family
HN018_RS12190	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HN018_RS12195	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HN018_RS12200	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HN018_RS12225	ENOG4105DYC	esterase
HN018_RS12255	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HN018_RS12275	ENOG4105BZS	acriflavin resistance protein
HN018_RS12280	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HN018_RS12290	ENOG4105VMP	Transcriptional regulator
HN018_RS12320	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HN018_RS12330	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HN018_RS12335	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HN018_RS12340	ENOG4105D6S	protein involved in catabolism of external DNA
HN018_RS12345	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HN018_RS12375	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HN018_RS12380	ENOG4107SJI	Dehydrogenase
HN018_RS12385	ENOG4105BZ8	glutamate synthase
HN018_RS12390	ENOG4107XGZ	Hydrolase
HN018_RS12400	ENOG4105BZU	Histidine kinase
HN018_RS12405	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_RS12415	ENOG4105F9F	transposase
HN018_RS12425	ENOG4105ECQ	AraC Family Transcriptional Regulator
HN018_RS12430	ENOG41062QD	Membrane
HN018_RS12435	ENOG4107QN1	sodium solute
HN018_RS12445	ENOG4105CNN	ABC, transporter
HN018_RS12450	ENOG4105C2J	ABC transporter
HN018_RS12455	ENOG4105DDV	Transcriptional regulator (LacI family
HN018_RS12460	ENOG4105BZU	Histidine kinase
HN018_RS12465	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HN018_RS12470	ENOG4105D9N	nucleoside
HN018_RS12475	ENOG4108R86	Transcriptional regulator
HN018_RS12480	ENOG4105CD3	dihydroorotase
HN018_RS12485	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HN018_RS12495	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HN018_RS12505	ENOG4105CCU	oxidase (Subunit III)
HN018_RS12510	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_RS12515	ENOG4105E2S	oxidase) subunit II
HN018_RS12530	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_RS12560	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HN018_RS12600	ENOG4105DY8	decarboxylase
HN018_RS12605	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
HN018_RS12640	ENOG4105D9R	oxidoreductase
HN018_RS12670	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HN018_RS12675	ENOG4105DZG	Dehydrogenase
HN018_RS12690	ENOG4108M3R	transcriptional activator CadC
HN018_RS12710	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HN018_RS12715	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HN018_RS12750	ENOG4105DSF	transport protein
HN018_RS12760	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN018_RS12765	ENOG4108W6C	Dehydrogenase
HN018_RS12775	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HN018_RS12780	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HN018_RS12800	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HN018_RS12815	ENOG4108Z7R	Chaperone CsaA
HN018_RS12820	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HN018_RS12825	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HN018_RS12855	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HN018_RS12860	ENOG4105C26	Dehydrogenase
HN018_RS12875	ENOG4107QRT	dEAD DEAH box helicase
HN018_RS12885	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HN018_RS12890	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HN018_RS12895	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HN018_RS12920	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HN018_RS12925	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HN018_RS12965	ENOG4105EAH	synthase
HN018_RS12985	ENOG4105BZU	Histidine kinase
HN018_RS12995	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_RS13000	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HN018_RS13010	ENOG4105E3A	(ABC) transporter
HN018_RS13015	ENOG4105DA5	(ABC) transporter
HN018_RS13020	ENOG4105C01	Dihydroxy-acid dehydratase
HN018_RS13030	ENOG4105CEY	Amp-dependent synthetase and ligase
HN018_RS13035	ENOG4105CUJ	penicillin amidase
HN018_RS13070	ENOG4108XFH	Transcriptional regulator
HN018_RS13080	ENOG4105CSH	Transporter
HN018_RS13165	ENOG4105F9F	transposase
HN018_RS13205	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HN018_RS13210	ENOG4105K46	50S ribosomal protein l27
HN018_RS13215	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HN018_RS13220	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HN018_RS13255	ENOG4107QX3	carboxylase
HN018_RS13260	ENOG4105C1G	acyl-Coa dehydrogenase
HN018_RS13265	ENOG4107QSN	dihydrolipoamide acetyltransferase
HN018_RS13270	ENOG4105CPP	Dehydrogenase, E1 component
HN018_RS13275	ENOG4107R0V	Pyruvate dehydrogenase
HN018_RS13280	ENOG4108YXU	transcriptional regulator AsnC family
HN018_RS13295	ENOG4105DNH	Major Facilitator
HN018_RS13310	ENOG4107ZSV	Receptor
HN018_RS13320	ENOG4105D82	Glutamate dehydrogenase
HN018_RS13330	ENOG4107S8C	mandelate racemase muconate lactonizing
HN018_RS13335	ENOG4105DUX	Transporter
HN018_RS13355	ENOG4105DJB	Major Facilitator Superfamily
HN018_RS13360	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HN018_RS13370	ENOG4105JXH	GntR family transcriptional regulator
HN018_RS13380	ENOG4105DJB	Major Facilitator Superfamily
HN018_RS13390	ENOG4105JSC	dimethylmenaquinone methyltransferase
HN018_RS13405	ENOG4105Y2X	UPF0335 protein
HN018_RS13410	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HN018_RS13430	ENOG4105QUH	Domain of unknown function (DUF2088)
HN018_RS13440	ENOG4105CPC	Aldo Keto reductase
HN018_RS13445	ENOG4105CNN	ABC, transporter
HN018_RS13465	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HN018_RS13475	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HN018_RS13480	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HN018_RS13485	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HN018_RS13490	ENOG4105C8N	cysteinyl-tRNA synthetase
HN018_RS13495	ENOG4107QI1	Mate efflux family protein
HN018_RS13500	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HN018_RS13505	ENOG4105CCU	oxidase (Subunit III)
HN018_RS13510	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_RS13515	ENOG4105E2S	oxidase) subunit II
HN018_RS13520	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HN018_RS13535	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HN018_RS13540	ENOG4105CF1	Alkylated DNA repair protein
HN018_RS13550	ENOG4105VPX	protein, conserved in bacteria
HN018_RS13595	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HN018_RS13615	ENOG4107T8Q	Glycosyl transferase (Group 1
HN018_RS13635	ENOG4105CHH	sulfate transporter
HN018_RS13640	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HN018_RS13655	ENOG4105DY2	Paraquat-inducible protein b
HN018_RS13685	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HN018_RS13705	ENOG4105DP0	ferredoxin-NADP reductase
HN018_RS13725	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_RS13730	ENOG4105F27	Major Facilitator
HN018_RS13740	ENOG4105CPC	Aldo Keto reductase
HN018_RS13745	ENOG4105E98	transcriptional regulator DeoR family
HN018_RS13755	ENOG4105C2J	ABC transporter
HN018_RS13760	ENOG4105CNN	ABC, transporter
HN018_RS13765	ENOG4107UEK	pfkb domain protein
HN018_RS13770	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HN018_RS13775	ENOG4105CHR	reductase
HN018_RS13790	ENOG4105EXG	Transcriptional regulator
HN018_RS13795	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HN018_RS13800	ENOG4107S2N	Type III effector Hrp-dependent
HN018_RS13805	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HN018_RS13820	ENOG4105KPV	Transcriptional regulator
HN018_RS13830	ENOG4105EA8	2-Nitropropane dioxygenase
HN018_RS13840	ENOG4108WBT	adenosyltransferase
HN018_RS13865	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HN018_RS13885	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_RS13890	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_RS13935	ENOG4105F27	Major Facilitator
HN018_RS13940	ENOG4108XFH	Transcriptional regulator
HN018_RS13960	ENOG4105CYM	Glutathione S-transferase
HN018_RS13965	ENOG4105CHR	reductase
HN018_RS13990	ENOG4105C7W	Xanthine dehydrogenase
HN018_RS13995	ENOG4105D25	secreted protein
HN018_RS14005	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HN018_RS14015	ENOG4107YUR	Cell division protein mraZ
HN018_RS14020	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HN018_RS14035	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HN018_RS14045	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HN018_RS14050	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HN018_RS14060	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HN018_RS14065	ENOG4105DFU	Cell wall formation (By similarity)
HN018_RS14070	ENOG4105D4A	Cell wall formation (By similarity)
HN018_RS14075	ENOG4105CPF	Cell wall formation (By similarity)
HN018_RS14080	ENOG4108UFP	Essential cell division protein (By similarity)
HN018_RS14085	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HN018_RS14090	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HN018_RS14100	ENOG4108IV0	ABC, transporter
HN018_RS14105	ENOG4105C0Z	ABC transporter
HN018_RS14115	ENOG4105C32	Amino acid ABC transporter (Permease)
HN018_RS14130	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HN018_RS14135	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HN018_RS14140	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_RS14145	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HN018_RS14150	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HN018_RS14155	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HN018_RS14160	ENOG4105BZU	Histidine kinase
HN018_RS14175	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HN018_RS14180	ENOG4105E2X	shikimate dehydrogenase
HN018_RS14200	ENOG4107ZT5	Thiol disulfide interchange protein
HN018_RS14205	ENOG4105CH7	arginosuccinase
HN018_RS14255	ENOG4108RVA	ribokinase
HN018_RS14280	ENOG4105CIS	alcohol dehydrogenase
HN018_RS14285	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HN018_RS14295	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_RS14310	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
HN018_RS14315	ENOG4105C9X	ppx gppa phosphatase
HN018_RS14320	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HN018_RS14345	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HN018_RS14350	ENOG4105CQZ	Histidine kinase
HN018_RS14355	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HN018_RS14360	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HN018_RS14365	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HN018_RS14380	ENOG4105CSH	Transporter
HN018_RS14385	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HN018_RS14390	ENOG4105C5H	ABC transporter
HN018_RS14395	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS14405	ENOG4105CWX	Alpha-1,2-mannosidase
HN018_RS14415	ENOG4105DU0	nucleoside hydrolase
HN018_RS14425	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_RS14430	ENOG4108UQ8	endoribonuclease L-psp
HN018_RS14440	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HN018_RS14445	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HN018_RS14455	ENOG4105FTV	AraC Family Transcriptional Regulator
HN018_RS14480	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HN018_RS14490	ENOG4105ESV	Glycosyl transferase, family 4
HN018_RS14505	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HN018_RS14550	ENOG4105C93	Xylose Isomerase
HN018_RS14555	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_RS14565	ENOG4105DFW	ABC transporter
HN018_RS14575	ENOG4108HWW	ABC transporter
HN018_RS14595	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HN018_RS14600	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HN018_RS14615	ENOG4108VYJ	response regulator receiver protein
HN018_RS14640	ENOG4105KTQ	flagellar basal-body rod protein
HN018_RS14645	ENOG4105CGA	flagellar basal-body rod protein FlgG
HN018_RS14655	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HN018_RS14670	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HN018_RS14690	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HN018_RS14720	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HN018_RS14730	ENOG4105E0F	Histidine kinase
HN018_RS14740	ENOG4108UM1	dedA family
HN018_RS14750	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HN018_RS14765	ENOG4105E4C	Lytic transglycosylase catalytic
HN018_RS14790	ENOG4105FXM	Copper resistance protein
HN018_RS14800	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HN018_RS14805	ENOG4107U9T	Pfam:Ribonuclease_BN
HN018_RS14815	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HN018_RS14825	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HN018_RS14835	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HN018_RS14850	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HN018_RS14855	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HN018_RS14860	ENOG4105C2C	drug resistance transporter, Bcr CflA
HN018_RS14870	ENOG4105CPC	Aldo Keto reductase
HN018_RS14890	ENOG4105DHJ	ABC, transporter
HN018_RS14905	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HN018_RS14945	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HN018_RS14950	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HN018_RS14965	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HN018_RS14975	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HN018_RS14990	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HN018_RS15020	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HN018_RS15040	ENOG4105CSP	Major Facilitator Superfamily
HN018_RS15045	ENOG4105EXW	epimerase dehydratase
HN018_RS15050	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN018_RS15065	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HN018_RS15070	ENOG4105BZA	Phosphoglycerate kinase
HN018_RS15105	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN018_RS15110	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HN018_RS15120	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HN018_RS15130	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HN018_RS15135	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HN018_RS15140	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HN018_RS15145	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HN018_RS15150	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HN018_RS15155	ENOG4105CQB	FAD linked oxidase domain protein
HN018_RS15165	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HN018_RS15180	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS15185	ENOG4105BZU	Histidine kinase
HN018_RS15200	ENOG4108YZN	class I peptide chain release factor
HN018_RS15205	ENOG4105TMB	Formate nitrite transporter
HN018_RS15220	ENOG41067HS	methyltransferase
HN018_RS15225	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HN018_RS15230	ENOG4105CEY	Amp-dependent synthetase and ligase
HN018_RS15235	ENOG4105CPC	Aldo Keto reductase
HN018_RS15255	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS15260	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_RS15265	ENOG4105C2I	pirin domain protein
HN018_RS15310	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HN018_RS15320	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HN018_RS15355	ENOG4105C2D	reductase
HN018_RS15380	ENOG4107QWE	)-transporter
HN018_RS15395	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN018_RS15400	ENOG4108TQ9	Histidine kinase
HN018_RS15410	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HN018_RS15445	ENOG4107QZW	Altronate oxidoreductase
HN018_RS15450	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS15460	ENOG4105EQN	UPF0261 protein
HN018_RS15485	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HN018_RS15500	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HN018_RS15505	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HN018_RS15510	ENOG4105C2J	ABC transporter
HN018_RS15515	ENOG4105F5R	ABC transporter
HN018_RS15525	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_RS15530	ENOG4105CG3	alpha amylase, catalytic region
HN018_RS15535	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HN018_RS15540	ENOG41082BR	50S ribosomal protein L35
HN018_RS15560	ENOG4105C5H	ABC transporter
HN018_RS15565	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HN018_RS15570	ENOG4108I5D	sulfate abc transporter
HN018_RS15575	ENOG4105ECW	sulfate abc transporter
HN018_RS15580	ENOG4108IJ6	ABC transporter
HN018_RS15590	ENOG4105E32	cytoplasmic protein
HN018_RS15595	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HN018_RS15605	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS15610	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_RS15645	ENOG4105C54	Major Facilitator superfamily
HN018_RS15650	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HN018_RS15675	ENOG4107T0X	DNA ligase
HN018_RS15720	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HN018_RS15730	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_RS15740	ENOG4105BZU	Histidine kinase
HN018_RS15755	ENOG4105CFU	surface antigen
HN018_RS15765	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HN018_RS15770	ENOG4105C9A	Phoh family
HN018_RS15775	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HN018_RS15780	ENOG4107RCQ	(CBS) domain
HN018_RS15785	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HN018_RS15800	ENOG4108UQY	Iron-storage protein
HN018_RS15810	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
HN018_RS15815	ENOG4105DJ9	glucan biosynthesis protein
HN018_RS15830	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS15840	ENOG4105CPQ	Dehydrogenase
HN018_RS15845	ENOG4105CNN	ABC, transporter
HN018_RS15855	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS15865	ENOG4108YZG	isomerase
HN018_RS15910	ENOG41067RQ	csbd family
HN018_RS15935	ENOG4105Y3U	Transglycosylase-associated protein
HN018_RS15940	ENOG4105ERH	Fumarylacetoacetate hydrolase
HN018_RS15950	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
HN018_RS15965	ENOG4107GFK	fumarate
HN018_RS15980	ENOG4107QJQ	Mate efflux family protein
HN018_RS15985	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HN018_RS15990	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HN018_RS15995	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HN018_RS16005	ENOG4105BZU	Histidine kinase
HN018_RS16015	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HN018_RS16020	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HN018_RS16035	ENOG4105SYT	Methylenetetrahydrofolate reductase
HN018_RS16055	ENOG4105C5H	ABC transporter
HN018_RS16065	ENOG4105F0N	pyrophosphate phospho-hydrolase
HN018_RS16105	ENOG4105C3R	Methionine synthase
HN018_RS16120	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HN018_RS16130	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HN018_RS16140	ENOG41089UC	methyltransferase, type 11
HN018_RS16155	ENOG4105DZ0	fad dependent oxidoreductase
HN018_RS16160	ENOG4105PGM	cation diffusion facilitator family transporter
HN018_RS16165	ENOG4105C2W	permease
HN018_RS16180	ENOG4105BZU	Histidine kinase
HN018_RS16185	ENOG4105BZU	Histidine kinase
HN018_RS16190	ENOG4105E39	Enoyl-CoA hydratase
HN018_RS16200	ENOG4105CKI	cobalamin synthesis protein
HN018_RS16210	ENOG4107STW	synthase
HN018_RS16215	ENOG4108RXX	maleylacetoacetate isomerase
HN018_RS16220	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HN018_RS16230	ENOG4105C3J	Cysteine desulfurase
HN018_RS16240	ENOG4105DHZ	alpha beta
HN018_RS16245	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HN018_RS16250	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HN018_RS16255	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS16270	ENOG4108Z40	Transcriptional regulator
HN018_RS16290	ENOG4105DQ4	alcohol dehydrogenase
HN018_RS16335	ENOG4105HHA	aminodeoxychorismate lyase
HN018_RS16340	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HN018_RS16345	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HN018_RS16355	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HN018_RS16360	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HN018_RS16370	ENOG4108I0C	methyltransferase
HN018_RS16385	ENOG4107SWE	Methyltransferase
HN018_RS16395	ENOG4105BZU	Histidine kinase
HN018_RS16410	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HN018_RS16415	ENOG4105KST	dependent repressor
HN018_RS16420	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HN018_RS16425	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HN018_RS16430	ENOG4105BZU	Histidine kinase
HN018_RS16435	ENOG4105C9K	Endothelin-converting enzyme 1
HN018_RS16445	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HN018_RS16470	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HN018_RS16480	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HN018_RS16485	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HN018_RS16490	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HN018_RS16505	ENOG4105EXC	Acyl-transferase
HN018_RS16510	ENOG4105C3G	gtp-binding protein
HN018_RS16515	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HN018_RS16520	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HN018_RS16530	ENOG4107TB6	phosphoglycerate mutase
HN018_RS16535	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HN018_RS16545	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HN018_RS16555	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HN018_RS16575	ENOG4105II7	pyrroline-5-carboxylate reductase
HN018_RS16590	ENOG4105K70	DNA-binding protein
HN018_RS16595	ENOG4106IQQ	
HN018_RS16615	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HN018_RS16620	ENOG4105DWV	Homoserine O-trans-acetylase
HN018_RS16625	ENOG4108N2Y	auxin Efflux
HN018_RS16635	ENOG4108459	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
HN018_RS16655	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HN018_RS16665	ENOG4108UQ8	endoribonuclease L-psp
HN018_RS16670	ENOG4105D64	Mechanosensitive ion channel
HN018_RS16690	ENOG4105F2M	alpha beta hydrolase fold-3 domain protein
HN018_RS16695	ENOG4105CUB	amino acid
HN018_RS16700	ENOG4105CUG	Oligopeptidase b
HN018_RS16710	ENOG4105E0K	tonB-dependent siderophore receptor
HN018_RS16745	ENOG4105CND	Glycosyl transferase, family 2
HN018_RS16760	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HN018_RS16820	ENOG4108K4C	ec 3.1.3.12
HN018_RS16845	ENOG4107RTZ	reductase
HN018_RS16870	ENOG4105D00	flagellar biosynthetic protein flhB
HN018_RS16875	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HN018_RS16885	ENOG4105UVF	flagellar hook-basal body complex protein fliE
HN018_RS16890	ENOG4108ZC9	flagellar basal-body rod protein flgc
HN018_RS16905	ENOG4105CN7	Flagellar biosynthetic protein FliP
HN018_RS16920	ENOG4105CXN	decarboxylase
HN018_RS16925	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HN018_RS16935	ENOG4105C9Q	fumarate hydratase class II
HN018_RS16945	ENOG4105C26	Dehydrogenase
HN018_RS16955	ENOG4105CQZ	Histidine kinase
HN018_RS16970	ENOG4108R85	Short chain dehydrogenase
HN018_RS16975	ENOG4105CXK	mandelate racemase muconate lactonizing
HN018_RS16985	ENOG4105CPQ	Dehydrogenase
HN018_RS16990	ENOG4105CNN	ABC, transporter
HN018_RS16995	ENOG4108F37	ATP-binding component of a transport system
HN018_RS17000	ENOG4105FCA	ABC transporter periplasmic-binding protein YphF
HN018_RS17005	ENOG4107EJG	GntR family transcriptional regulator
HN018_RS17010	ENOG4108JQ1	Dehydrogenase
HN018_RS17025	ENOG41069NU	Nitroreductase
HN018_RS17035	ENOG4108V06	Glutathione peroxidase
HN018_RS17045	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HN018_RS17050	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HN018_RS17055	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HN018_RS17060	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HN018_RS17065	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HN018_RS17070	ENOG4105K59	histidine triad (HIT) protein
HN018_RS17080	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_RS17085	ENOG4105BZU	Histidine kinase
HN018_RS17110	ENOG4108JJ7	ABC transporter
HN018_RS17115	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HN018_RS17125	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HN018_RS17130	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HN018_RS17135	ENOG4105CXT	aspartate transcarbamylase
HN018_RS17140	ENOG4105CD3	dihydroorotase
HN018_RS17145	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HN018_RS17150	ENOG4105C79	DNA protecting protein DprA
HN018_RS17160	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HN018_RS17165	ENOG4105CN1	protease
HN018_RS17185	ENOG4107RDJ	Sulfotransferase
HN018_RS17190	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_RS17205	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HN018_RS17210	ENOG4105D3R	alkyl hydroperoxide reductase
HN018_RS17215	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HN018_RS17230	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HN018_RS17235	ENOG4105BZS	acriflavin resistance protein
HN018_RS17240	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN018_RS17250	ENOG4105JZI	cytochrome P450
HN018_RS17255	ENOG4105C8S	subunit m
HN018_RS17260	ENOG4105VGJ	Virulence-associated protein
HN018_RS17265	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HN018_RS17270	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HN018_RS17280	ENOG4105CV8	reductase
HN018_RS17285	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HN018_RS17290	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HN018_RS17300	ENOG4105DTN	riboflavin biosynthesis protein ribF
HN018_RS17305	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
HN018_RS17310	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
HN018_RS17315	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HN018_RS17335	ENOG4105C8Y	Acetylornithine aminotransferase
HN018_RS17340	ENOG4105DBV	ornithine carbamoyltransferase
HN018_RS17365	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HN018_RS17370	ENOG4105CQ7	ATP-dependent helicase
HN018_RS17380	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS17385	ENOG4106F60	Histidine kinase
HN018_RS17405	ENOG4106WTF	Glycosyl transferase, family 2
HN018_RS17415	ENOG4105CNI	cell division protein FtsW
HN018_RS17425	ENOG4105C7K	acetolactate synthase
HN018_RS17435	ENOG4106K28	UPF0283 membrane protein
HN018_RS17440	ENOG4105CM6	amino acid regulated cytosolic protein
HN018_RS17455	ENOG4105CJN	penicillin-binding protein
HN018_RS17465	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HN018_RS17490	ENOG4105C12	Phosphoribosylglycinamide synthetase
HN018_RS17495	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HN018_RS17530	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HN018_RS17535	ENOG4105C9M	aspartyl-trna synthetase
HN018_RS17560	ENOG4105C1J	atp-dependent rna helicase
HN018_RS17575	ENOG4105DKQ	ROK family
HN018_RS17585	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HN018_RS17590	ENOG4105CTB	Polyprenyl synthetase
HN018_RS17595	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HN018_RS17600	ENOG4105DX0	Hemolysin A
HN018_RS17610	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HN018_RS17620	ENOG4105DEI	Mannitol dehydrogenase
HN018_RS17625	ENOG4105CMG	Carbohydrate kinase
HN018_RS17660	ENOG4105CDH	Citrulline--aspartate ligase
HN018_RS17675	ENOG4107T8J	thymidine kinase
HN018_RS17680	ENOG4105C31	Tryptophanyl-tRNA synthetase
HN018_RS17710	ENOG4105DRS	transport system, permease
HN018_RS17725	ENOG4105C4W	S-formylglutathione hydrolase
HN018_RS17730	ENOG4107QPD	alcohol dehydrogenase
HN018_RS17735	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HN018_RS17740	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HN018_RS17750	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
HN018_RS17755	ENOG4105CK2	sodium dicarboxylate symporter
HN018_RS17765	ENOG4105C2J	ABC transporter
HN018_RS17770	ENOG4105CNN	ABC, transporter
HN018_RS17775	ENOG4105C7W	Xanthine dehydrogenase
HN018_RS17780	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HN018_RS17785	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HN018_RS17790	ENOG4105C3F	Signal peptidase i
HN018_RS17810	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HN018_RS17815	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HN018_RS17820	ENOG4105E0X	reductase
HN018_RS17825	ENOG4105NCT	RNA Polymerase
HN018_RS17845	ENOG4105C2J	ABC transporter
HN018_RS17850	ENOG4105DIH	basic membrane
HN018_RS17865	ENOG4105FFC	UPF0187 protein
HN018_RS17875	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HN018_RS17880	ENOG4106TD9	Diguanylate cyclase
HN018_RS17895	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HN018_RS17900	ENOG4105CHR	reductase
HN018_RS17910	ENOG4105CHR	reductase
HN018_RS17915	ENOG4105C2J	ABC transporter
HN018_RS17925	ENOG4105CNN	ABC, transporter
HN018_RS17930	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HN018_RS17935	ENOG4108IUS	Transketolase
HN018_RS17940	ENOG4108HHA	Transketolase
HN018_RS17945	ENOG4105BZU	Histidine kinase
HN018_RS17965	ENOG4108I0Y	(ABC) transporter
HN018_RS17970	ENOG4108UJV	acyl-CoA thioesterase i
HN018_RS17980	ENOG4105ETU	transcriptional activator (TenA
HN018_RS17985	ENOG4108YI8	ABC transporter
HN018_RS17990	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HN018_RS17995	ENOG4105C8Q	Methyl-accepting chemotaxis
HN018_RS18010	ENOG4105BZ1	(ABC) transporter
HN018_RS18015	ENOG4107RE3	peptidase, S41
HN018_RS18030	ENOG41073TP	transcriptional regulator
HN018_RS18040	ENOG4105C2J	ABC transporter
HN018_RS18045	ENOG4105CNN	ABC, transporter
HN018_RS18055	ENOG4105CHR	reductase
HN018_RS18060	ENOG4105CNN	ABC, transporter
HN018_RS18065	ENOG4105C2J	ABC transporter
HN018_RS18070	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS18080	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HN018_RS18085	ENOG4105C0A	alcohol dehydrogenase
HN018_RS18095	ENOG4105C2J	ABC transporter
HN018_RS18100	ENOG4105CNN	ABC, transporter
HN018_RS18120	ENOG4105CMG	Carbohydrate kinase
HN018_RS18130	ENOG4106KNT	transcriptional regulator
HN018_RS18140	ENOG4105CHR	reductase
HN018_RS18150	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
HN018_RS18155	ENOG4105F5R	ABC transporter
HN018_RS18160	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
HN018_RS18175	ENOG4105E98	transcriptional regulator DeoR family
HN018_RS18185	ENOG4105C9F	isomerase
HN018_RS18190	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HN018_RS18195	ENOG4107QR9	Iron-sulfur cluster binding protein
HN018_RS18210	ENOG4108HRK	Histidine kinase
HN018_RS18215	ENOG4108VAC	response regulator
HN018_RS18320	ENOG4105D75	Capsular exopolysaccharide family
HN018_RS18330	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HN018_RS18335	ENOG4108UM1	dedA family
HN018_RS18340	ENOG4105WH1	Two component transcriptional regulator luxr family
HN018_RS18345	ENOG4105D3Q	Sugar transferase
HN018_RS18385	ENOG4108VX5	3-methyladenine DNA glycosylase
HN018_RS18400	ENOG4108KSB	HipA-like N-terminal domain
HN018_RS18410	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HN018_RS18425	ENOG4105K63	Thioredoxin
HN018_RS18430	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HN018_RS18435	ENOG4105W49	UPF0434 protein
HN018_RS18440	ENOG41080VW	acetyltransferase
HN018_RS18445	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN018_RS18455	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HN018_RS18465	ENOG4105CPQ	Dehydrogenase
HN018_RS18470	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HN018_RS18475	ENOG4108ZP8	Acetolactate synthase small subunit
HN018_RS18480	ENOG4105C7K	acetolactate synthase
HN018_RS18485	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HN018_RS18490	ENOG4105EAC	phosphoserine phosphatase
HN018_RS18500	ENOG4105C8Y	Acetylornithine aminotransferase
HN018_RS18520	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HN018_RS18525	ENOG410904N	short-chain dehydrogenase reductase
HN018_RS18530	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HN018_RS18535	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HN018_RS18580	ENOG4107RCI	amp-dependent synthetase and ligase
HN018_RS18620	ENOG4107TE5	Lipid kinase
HN018_RS18630	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN018_RS18655	ENOG4105ECK	Fatty Acid Desaturase
HN018_RS18660	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HN018_RS18665	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN018_RS18735	ENOG4107RD7	Flagellar Motor Protein, MotA
HN018_RS18740	ENOG4105ER2	Ompa motb domain protein
HN018_RS18755	ENOG4105F7P	transcriptional regulator AsnC family
HN018_RS18760	ENOG4105C3M	thioredoxin reductase
HN018_RS18765	ENOG4105GZI	Transcriptional regulator
HN018_RS18785	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HN018_RS18790	ENOG4105D07	Signal peptide peptidase, SppA
HN018_RS18795	ENOG4107RGH	Aldehyde dehydrogenase
HN018_RS18815	ENOG41087AY	ADP-Ribose pyrophosphatase
HN018_RS18830	ENOG4107XR4	alpha beta
HN018_RS18835	ENOG4105CEY	Amp-dependent synthetase and ligase
HN018_RS18855	ENOG4105DFP	Integrase
HN018_RS18890	ENOG4107TTQ	Alpha beta hydrolase fold
HN018_RS18900	ENOG4105C2M	dna polymerase I
HN018_RS18910	ENOG4105DEF	Extracellular solute-binding protein, family 5
HN018_RS18915	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_RS18920	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HN018_RS18935	ENOG4108UPT	UPF0178 protein
HN018_RS18945	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HN018_RS18955	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HN018_RS18965	ENOG4108K4B	hydrolase
HN018_RS18970	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HN018_RS18975	ENOG4108J5G	6-phosphogluconate dehydrogenase
HN018_RS18980	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HN018_RS19015	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HN018_RS19030	ENOG410642W	LysR family Transcriptional regulator
HN018_RS19035	ENOG4105CHR	reductase
HN018_RS19040	ENOG4105CPQ	Dehydrogenase
HN018_RS19055	ENOG4105E1J	oxidoreductase
HN018_RS19070	ENOG4105E45	Histidinol-phosphate aminotransferase
HN018_RS19085	ENOG4105CPW	cytochrome b561
HN018_RS19090	ENOG4105X1Q	TOBE domain protein
HN018_RS19115	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HN018_RS19120	ENOG4105E0C	molybdate abc transporter
HN018_RS19125	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HN018_RS19130	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HN018_RS19145	ENOG4105D8X	mechanosensitive ion channel
HN018_RS19155	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HN018_RS19175	ENOG4105CNV	Aldolase
HN018_RS19195	ENOG4105DWV	Homoserine O-trans-acetylase
HN018_RS19245	ENOG4105E4C	Lytic transglycosylase catalytic
HN018_RS19340	ENOG4105F9F	transposase
HN018_RS19400	ENOG4105F9F	transposase
HN018_RS19430	ENOG4105F5W	AtP-binding protein
HN018_RS19455	ENOG410903D	sensor protein
HN018_RS19460	ENOG4105CQZ	Histidine kinase
HN018_RS19470	ENOG4105E5H	Transposase
HN018_RS19475	ENOG4105E5H	Transposase
HN018_RS19480	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS19495	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS19610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_RS19615	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_RS19640	ENOG4105NWN	ApaG protein
HN018_RS19650	ENOG4105EUJ	GTP cyclohydrolase i
HN018_RS19660	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HN018_RS19685	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HN018_RS19690	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HN018_RS19695	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HN018_RS19710	ENOG4105EXC	Acyl-transferase
HN018_RS19720	ENOG4105EXC	Acyl-transferase
HN018_RS19735	ENOG4106A3M	Cytochrome p-450
HN018_RS19740	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN018_RS19765	ENOG4108RXX	maleylacetoacetate isomerase
HN018_RS19785	ENOG4105BZU	Histidine kinase
HN018_RS19805	ENOG4108R9S	DSBA oxidoreductase
HN018_RS19840	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN018_RS19845	ENOG4108HRK	Histidine kinase
HN018_RS19850	ENOG4105CIR	epoxide hydrolase
HN018_RS19865	ENOG4105C84	Histidine ammonia-lyase
HN018_RS19870	ENOG4105CIF	Ornithine Cyclodeaminase
HN018_RS19875	ENOG4105DJB	Major Facilitator Superfamily
HN018_RS19890	ENOG4107QUY	Guanine deaminase
HN018_RS19895	ENOG4105C1J	atp-dependent rna helicase
HN018_RS19910	ENOG4105BZU	Histidine kinase
HN018_RS19915	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS19925	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HN018_RS19930	ENOG4105E2Z	phosphate ABC transporter (Permease
HN018_RS19935	ENOG4105C8U	phosphate abc transporter
HN018_RS19940	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HN018_RS19955	ENOG41062B0	ABC transporter, permease
HN018_RS19960	ENOG4105C2J	ABC transporter
HN018_RS19975	ENOG4105EXG	Transcriptional regulator
HN018_RS19995	ENOG4106G6Q	Transcriptional regulator
HN018_RS20015	ENOG4105BZU	Histidine kinase
HN018_RS20020	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HN018_RS20025	ENOG4105CUV	Homoserine Kinase
HN018_RS20030	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HN018_RS20040	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HN018_RS20055	ENOG4105C6X	Major Facilitator
HN018_RS20060	ENOG4105EPD	Oligopeptide transporter, Opt family
HN018_RS20065	ENOG4105DEN	Luciferase family
HN018_RS20070	ENOG4107Z6I	Thiamine biosynthesis protein
HN018_RS20110	ENOG4108VNY	MOSC domain protein
HN018_RS20135	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_RS20150	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HN018_RS20165	ENOG4105CKK	Glycosyl transferase, family 2
HN018_RS20175	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HN018_RS20190	ENOG4107PQ6	Inherit from NOG: atp synthase
HN018_RS20195	ENOG4105DBE	peroxidase
HN018_RS20210	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HN018_RS20215	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HN018_RS20220	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HN018_RS20230	ENOG4105EQ0	Major Facilitator superfamily
HN018_RS20235	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HN018_RS20240	ENOG4105E1F	short-chain dehydrogenase reductase
HN018_RS20245	ENOG4105WMT	general secretion pathway protein h
HN018_RS20250	ENOG410602S	Transferase
HN018_RS20275	ENOG41090VX	general secretion pathway protein L
HN018_RS20290	ENOG4105GVR	general secretion pathway protein D
HN018_RS20300	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HN018_RS20305	ENOG4108DMA	Nad-dependent epimerase dehydratase
HN018_RS20315	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HN018_RS20320	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HN018_RS20325	ENOG4105BZS	acriflavin resistance protein
HN018_RS20330	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HN018_RS20335	ENOG4108IG5	Transcriptional regulator
HN018_RS20345	ENOG4105C26	Dehydrogenase
HN018_RS20350	ENOG4108RVA	ribokinase
HN018_RS20360	ENOG4107R9N	ABC transporter
HN018_RS20365	ENOG4105CNN	ABC, transporter
HN018_RS20380	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HN018_RS20385	ENOG4105E98	transcriptional regulator DeoR family
HN018_RS20390	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS20395	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
HN018_RS20405	ENOG4105DKT	Transcriptional regulator
HN018_RS20415	ENOG4105CNN	ABC, transporter
HN018_RS20435	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HN018_RS20440	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HN018_RS20445	ENOG4105ECK	Fatty Acid Desaturase
HN018_RS20455	ENOG4105C26	Dehydrogenase
HN018_RS20460	ENOG4105DH8	myo-inositol catabolism
HN018_RS20465	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
HN018_RS20470	ENOG4105D7K	pfkb domain protein
HN018_RS20475	ENOG4105D7Q	type ii secretion system
HN018_RS20480	ENOG4107QHF	type ii secretion system protein e
HN018_RS20490	ENOG4108VAU	general secretion pathway protein G
HN018_RS20510	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_RS20530	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HN018_RS20535	ENOG4105D01	(LipO)protein
HN018_RS20540	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HN018_RS20545	ENOG4108UMI	ABC transporter, permease
HN018_RS20560	ENOG4105K70	DNA-binding protein
HN018_RS20565	ENOG4105C5R	Aminotransferase
HN018_RS20570	ENOG4105C88	aminopeptidase
HN018_RS20575	ENOG4107STW	synthase
HN018_RS20585	ENOG4105DJV	ribulose-phosphate 3-epimerase
HN018_RS20590	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HN018_RS20605	ENOG4105DFA	alanine racemase domain protein
HN018_RS20610	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HN018_RS20615	ENOG4105CSA	Coproporphyrinogen iii oxidase
HN018_RS20625	ENOG4108RU0	short-chain dehydrogenase reductase
HN018_RS20635	ENOG4105E4C	Lytic transglycosylase catalytic
HN018_RS20645	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_RS20655	ENOG4105TXM	Domain of unknown function (DUF3576)
HN018_RS20660	ENOG4105C8T	Leucyl-tRNA synthetase
HN018_RS20685	ENOG4105BZP	glycoside hydrolase 15-related
HN018_RS20695	ENOG4107SFQ	iron-sulfur binding
HN018_RS20725	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_RS20750	ENOG4108RH0	Crea protein
HN018_RS20780	ENOG4105C6K	Malic enzyme
HN018_RS20785	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HN018_RS20815	ENOG41087YS	Phage shock protein A
HN018_RS20820	ENOG4105E51	psp operon transcriptional activator
HN018_RS20825	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HN018_RS20830	ENOG4105E0X	reductase
HN018_RS20860	ENOG4105CTX	dehydratase
HN018_RS20865	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS20870	ENOG4105C2J	ABC transporter
HN018_RS20875	ENOG4105CNN	ABC, transporter
HN018_RS20880	ENOG4105CNN	ABC, transporter
HN018_RS20885	ENOG4105EMU	Dehydrogenase
HN018_RS20890	ENOG4105DUX	Transporter
HN018_RS20900	ENOG4105C34	Pseudouridine synthase
HN018_RS20905	ENOG4105EU0	Major facilitator Superfamily
HN018_RS20925	ENOG4105C2J	ABC transporter
HN018_RS20930	ENOG4105CNN	ABC, transporter
HN018_RS20935	ENOG4105CNN	ABC, transporter
HN018_RS20950	ENOG4105CMG	Carbohydrate kinase
HN018_RS20955	ENOG4107RUY	(E1 component), alpha subunit
HN018_RS20960	ENOG4105CPP	Dehydrogenase, E1 component
HN018_RS20965	ENOG4107TTQ	Alpha beta hydrolase fold
HN018_RS20975	ENOG4105C2J	ABC transporter
HN018_RS20980	ENOG4105CNN	ABC, transporter
HN018_RS20985	ENOG4105CHR	reductase
HN018_RS20990	ENOG4105CHR	reductase
HN018_RS21000	ENOG4106H78	methyltransferase
HN018_RS21005	ENOG4105FE9	pseudouridine synthase
HN018_RS21010	ENOG4108Z86	Glutamine amidotransferase
HN018_RS21015	ENOG4108Z6B	deaminase
HN018_RS21030	ENOG4107QNK	)-transporter
HN018_RS21080	ENOG4105GVF	(ABC) transporter
HN018_RS21085	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HN018_RS21090	ENOG4105E2Y	ABC, transporter
HN018_RS21095	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HN018_RS21115	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HN018_RS21145	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HN018_RS21150	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HN018_RS21155	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HN018_RS21160	ENOG4105KB8	(LipO)protein
HN018_RS21165	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HN018_RS21170	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HN018_RS21185	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HN018_RS21190	ENOG4105CE4	GlcNAc 6-P deacetylase
HN018_RS21195	ENOG41067RQ	csbd family
HN018_RS21210	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HN018_RS21215	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HN018_RS21220	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HN018_RS21225	ENOG4105DAS	pts system
HN018_RS21250	ENOG4105FAV	ABC, transporter
HN018_RS21255	ENOG4105FDK	ABC transporter
HN018_RS21265	ENOG4105MYN	Zinc uptake regulation protein
HN018_RS21280	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HN018_RS21290	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HN018_RS21295	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HN018_RS21300	ENOG4107QUT	magnesium and cobalt transport protein CorA
HN018_RS21315	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HN018_RS21320	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HN018_RS21325	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HN018_RS21330	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HN018_RS21335	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
HN018_RS21355	ENOG4108YXA	Membrane
HN018_RS21360	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HN018_RS21365	ENOG4108UHJ	MAF-like protein
HN018_RS21380	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
HN018_RS21385	ENOG4107Y2X	deaminase
HN018_RS21410	ENOG4105WMR	Protein CrcB homolog
HN018_RS21420	ENOG4105Y49	secretion protein, HlyD family
HN018_RS21430	ENOG4105DSW	Fusaric acid resistance protein
HN018_RS21445	ENOG4105F9F	transposase
HN018_RS21470	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HN018_RS21480	ENOG4108MP6	LysR family Transcriptional regulator
HN018_RS21505	ENOG4105CBN	LysR family transcriptional regulator
HN018_RS21515	ENOG4108W6C	Dehydrogenase
HN018_RS21530	ENOG4105F5W	AtP-binding protein
HN018_RS21550	ENOG4105C0B	DNA polymerase III (alpha subunit)
HN018_RS21575	ENOG4106J7G	oxidoreductase
HN018_RS21585	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HN018_RS21595	ENOG4105CP7	Triose-phosphate isomerase
HN018_RS21600	ENOG4108YZG	isomerase
HN018_RS21610	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS21620	ENOG4105C2J	ABC transporter
HN018_RS21625	ENOG4105CNN	ABC, transporter
HN018_RS21630	ENOG41089GP	Oxidoreductase domain protein
HN018_RS21640	ENOG4108QBF	Transcriptional regulator
HN018_RS21645	ENOG4105CPC	Aldo Keto reductase
HN018_RS21655	ENOG4105D7T	ABC transporter
HN018_RS21690	ENOG4105CSU	acyl-Coa dehydrogenase
HN018_RS21700	ENOG4105CHU	acetyl-coa acetyltransferase
HN018_RS21710	ENOG4105CEY	Amp-dependent synthetase and ligase
HN018_RS21715	ENOG4108Z6Z	Transcriptional regulator
HN018_RS21720	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN018_RS21755	ENOG4105CI3	gtp-binding protein typa
HN018_RS21765	ENOG4105EYM	Major Facilitator superfamily
HN018_RS21770	ENOG4105CNG	UPF0061 protein
HN018_RS21780	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
HN018_RS21795	ENOG4105C10	Electron transfer flavoprotein
HN018_RS21800	ENOG4105TPV	
HN018_RS21805	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HN018_RS21810	ENOG4105JSC	dimethylmenaquinone methyltransferase
HN018_RS21815	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_RS21820	ENOG4105E2S	oxidase) subunit II
HN018_RS21830	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HN018_RS21845	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN018_RS21880	ENOG4105E5H	Transposase
HN018_RS21890	ENOG4105E5H	Transposase
HN018_RS21940	ENOG4105BZU	Histidine kinase
HN018_RS21965	ENOG4105E5H	Transposase
HN018_RS21970	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS21975	ENOG41061A5	transposase
HN018_RS22050	ENOG4105BZU	Histidine kinase
HN018_RS22055	ENOG4108VYJ	response regulator receiver protein
HN018_RS22060	ENOG4105BZU	Histidine kinase
HN018_RS22085	ENOG4105F5W	AtP-binding protein
HN018_RS22225	ENOG4105BZP	glycoside hydrolase 15-related
HN018_RS22240	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HN018_RS22245	ENOG4105CCU	oxidase (Subunit III)
HN018_RS22280	ENOG4105CW7	secretion protein, HlyD family
HN018_RS22305	ENOG4105VUF	Transcriptional regulator
HN018_RS22315	ENOG4105E5H	Transposase
HN018_RS22320	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS22330	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
HN018_RS22370	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_RS22375	ENOG4108KEZ	Dehydrogenase
HN018_RS22385	ENOG4105CC0	LysR family Transcriptional regulator
HN018_RS22390	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HN018_RS22410	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS22415	ENOG4105E5H	Transposase
HN018_RS22460	ENOG4105UMD	exodeoxyribonuclease X
HN018_RS22475	ENOG4105K70	DNA-binding protein
HN018_RS22495	ENOG4106TD9	Diguanylate cyclase
HN018_RS22500	ENOG4105BZU	Histidine kinase
HN018_RS22545	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HN018_RS22550	ENOG4105BZU	Histidine kinase
HN018_RS22555	ENOG4105CQZ	Histidine kinase
HN018_RS22585	ENOG4105F5W	AtP-binding protein
HN018_RS22590	ENOG4105M74	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HN018_RS22595	ENOG4105BZU	Histidine kinase
HN018_RS22630	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HN018_RS22645	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_RS22660	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HN018_RS22670	ENOG4105C3U	ABC transporter
HN018_RS22680	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_RS22700	ENOG4105C0B	DNA polymerase III (alpha subunit)
HN018_RS22735	ENOG4105VTR	Integrase
HN018_RS22790	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS22825	ENOG4105CHR	reductase
HN018_RS22830	ENOG4105DRR	Transcriptional regulator, GntR family
HN018_RS22835	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_RS22870	ENOG4105E1J	oxidoreductase
HN018_RS22885	ENOG4105DRP	amino acid AbC transporter
HN018_RS22890	ENOG4105EZ7	amino acid ABC transporter
HN018_RS22900	ENOG4105CD3	dihydroorotase
HN018_RS22915	ENOG4105CDA	abc transporter atp-binding protein
HN018_RS22920	ENOG41080HI	glycine oxidase
HN018_RS22935	ENOG4105FDP	GntR family transcriptional regulator
HN018_RS22945	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HN018_RS22960	ENOG4105C26	Dehydrogenase
HN018_RS22985	ENOG4108JQ1	Dehydrogenase
HN018_RS22990	ENOG4107F9Y	LysR family transcriptional regulator
HN018_RS22995	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HN018_RS23000	ENOG4108BAS	reductase
HN018_RS23010	ENOG4105F0F	Oxalate decarboxylase
HN018_RS23035	ENOG4105DJB	Major Facilitator Superfamily
HN018_RS23045	ENOG4105DG4	malate L-lactate dehydrogenase
HN018_RS23060	ENOG4108BAS	reductase
HN018_RS23075	ENOG4105E5H	Transposase
HN018_RS23080	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS23115	ENOG4108BUD	transposase
HN018_RS23155	ENOG4105F5W	AtP-binding protein
HN018_RS23160	ENOG4105D70	Integrase catalytic subunit
HN018_RS23185	ENOG4105GAK	amidohydrolase 2
HN018_RS23195	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HN018_RS23200	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HN018_RS23215	ENOG4108BUD	transposase
HN018_RS23510	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HN018_RS23515	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HN018_RS23540	ENOG4108RAV	Conserved protein
HN018_RS23565	ENOG4108UUM	single-stranded DNA-binding protein
HN018_RS23600	ENOG4105FA0	parb-like partition protein
HN018_RS23615	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_RS23705	ENOG4105C0D	helicase
HN018_RS23735	ENOG4105C4R	Atp-dependent dna helicase
HN018_RS23760	ENOG4105XMH	SpoVT AbrB domain protein
HN018_RS23825	ENOG4105EGS	Mechanosensitive ion channel
HN018_RS23830	ENOG4105E5H	Transposase
HN018_RS23835	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS23995	ENOG4107U9T	Pfam:Ribonuclease_BN
HN018_RS24045	ENOG4105BZP	glycoside hydrolase 15-related
HN018_RS24055	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HN018_RS24060	ENOG4105CCU	oxidase (Subunit III)
HN018_RS24095	ENOG4107QJE	Chromosome Partitioning Protein
HN018_RS24135	ENOG4108C33	Resolvase
HN018_RS24230	ENOG4108UUM	single-stranded DNA-binding protein
HN018_RS24280	ENOG4105F5W	AtP-binding protein
HN018_RS24300	ENOG4105CHR	reductase
HN018_RS24335	ENOG4108UHU	Aldolase
HN018_RS24340	ENOG4108Y83	glucose-6-phosphate isomerase
HN018_RS24345	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS24355	ENOG4105CNN	ABC, transporter
HN018_RS24360	ENOG4105CMG	Carbohydrate kinase
HN018_RS24365	ENOG4105CHR	reductase
HN018_RS24380	ENOG4105CR8	Transcriptional regulator
HN018_RS24385	ENOG4108JA1	polyketide synthase
HN018_RS24395	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HN018_RS24405	ENOG4105CF7	AraC family transcriptional regulator
HN018_RS24430	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS24480	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HN018_RS24485	ENOG4105K6T	rare lipoprotein A
HN018_RS24515	ENOG4105F5W	AtP-binding protein
HN018_RS24570	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
HN018_RS24575	ENOG4105C26	Dehydrogenase
HN018_RS24585	ENOG4105F9F	transposase
HN018_RS24615	ENOG4105C57	major facilitator superfamily
HN018_RS24630	ENOG4105C7K	acetolactate synthase
HN018_RS24640	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HN018_RS24650	ENOG4108RMU	ferritin dps family protein
HN018_RS24670	ENOG4105BZU	Histidine kinase
HN018_RS24700	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HN018_RS24735	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS24770	ENOG4105F5W	AtP-binding protein
HN018_RS24865	ENOG4108BUD	transposase
HN018_RS24890	ENOG4106TD9	Diguanylate cyclase
HN018_RS24910	ENOG4105K70	DNA-binding protein
HN018_RS24920	ENOG4105UMD	exodeoxyribonuclease X
HN018_RS25080	ENOG4105EMU	Dehydrogenase
HN018_RS25105	ENOG4108BUD	transposase
HN018_RS25155	ENOG4105BZU	Histidine kinase
HN018_RS25230	ENOG4105CXN	decarboxylase
HN018_RS25245	ENOG4108PHJ	Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response
HN018_RS25255	ENOG4105DWY	Agmatine deiminase
HN018_RS25270	ENOG4105BZU	Histidine kinase
HN018_RS25290	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
HN018_RS25295	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HN018_RS25300	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HN018_RS25315	ENOG4107EFR	Flavocytochrome c
HN018_RS25320	ENOG4105C3M	thioredoxin reductase
HN018_RS25325	ENOG41080XP	Cbs domain
HN018_RS25335	ENOG4105CQZ	Histidine kinase
HN018_RS25360	ENOG4105VP2	Transcriptional regulator, Crp Fnr family
HN018_RS25375	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_RS25380	ENOG4105CFG	Acts as a chaperone (By similarity)
HN018_RS25410	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HN018_RS25415	ENOG4105R5N	Phosphoribosyl-dephospho-CoA transferase
HN018_RS25430	ENOG4108459	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
HN018_RS25440	ENOG4108N2Y	auxin Efflux
HN018_RS25450	ENOG4105C71	hydrolase family 65, central catalytic
HN018_RS25455	ENOG4107URF	beta-phospho-glucomutase
HN018_RS25480	ENOG4107QX8	SPFH domain, Band 7 family protein
HN018_RS25510	ENOG4105CSR	polyphosphate kinase 2
HN018_RS25545	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HN018_RS25550	ENOG4105CP7	Triose-phosphate isomerase
HN018_RS25570	ENOG4105E2V	Glycosyltransferase 36
HN018_RS25605	ENOG4108ZM9	phosphoglycerate mutase
HN018_RS25610	ENOG4107R1Y	fructose-bisphosphate aldolase
HN018_RS25615	ENOG4107QRI	Phosphoketolase
HN018_RS25620	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HN018_RS25630	ENOG4105CP7	Triose-phosphate isomerase
HN018_RS25645	ENOG4108BUD	transposase
HN018_RS25655	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HN018_RS25700	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HN018_RS25715	ENOG4105E5H	Transposase
HN018_RS25720	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS25735	ENOG4108YZG	isomerase
HN018_RS25740	ENOG4105BZU	Histidine kinase
HN018_RS25775	ENOG4105DQ4	alcohol dehydrogenase
HN018_RS25790	ENOG4105IPI	Membrane
HN018_RS25845	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HN018_RS25870	ENOG4107R0R	NADH dehydrogenase subunit g
HN018_RS25885	ENOG4107QRI	Phosphoketolase
HN018_RS25930	ENOG4105YES	addiction module antidote protein
HN018_RS25960	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
HN018_RS25965	ENOG4107QJE	Chromosome Partitioning Protein
HN018_RS25975	ENOG4105F5W	AtP-binding protein
HN018_RS26010	ENOG4107QMS	site-determining protein
HN018_RS26025	ENOG4105CDU	Replicative dna helicase
HN018_RS26040	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HN018_RS26065	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HN018_RS26090	ENOG4107GRR	phosphate transport regulator
HN018_RS26125	ENOG4105CNN	ABC, transporter
HN018_RS26130	ENOG4105CNN	ABC, transporter
HN018_RS26135	ENOG4105C2J	ABC transporter
HN018_RS26140	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_RS26180	ENOG4108BUD	transposase
HN018_RS26210	ENOG4105C2J	ABC transporter
HN018_RS26215	ENOG4108HWW	ABC transporter
HN018_RS26255	ENOG4105F5W	AtP-binding protein
HN018_RS26295	ENOG4105E0F	Histidine kinase
HN018_RS26305	ENOG410903C	(LipO)protein
HN018_RS26315	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_RS26330	ENOG4105D70	Integrase catalytic subunit
HN018_RS26355	ENOG4105BZU	Histidine kinase
HN018_RS26370	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
HN018_RS26420	ENOG4105E5H	Transposase
HN018_RS26425	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS26430	ENOG4105F9F	transposase
HN018_RS26465	ENOG4105E5H	Transposase
HN018_RS26470	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS26475	ENOG41061A5	transposase
HN018_RS26480	ENOG4105BZU	Histidine kinase
HN018_RS26515	ENOG4105F5W	AtP-binding protein
HN018_RS26520	ENOG4105DQ6	Transposase
HN018_RS26530	ENOG4105BZU	Histidine kinase
HN018_RS26545	ENOG4105KVH	Transcriptional regulator
HN018_RS26570	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_RS26590	ENOG4105E5H	Transposase
HN018_RS26595	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS26615	ENOG4105EEQ	Na H antiporter
HN018_RS26645	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_RS26650	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HN018_RS26655	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HN018_RS26660	ENOG4105DUM	transcriptional regulator, lysR family
HN018_RS26785	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS26800	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HN018_RS26805	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HN018_RS26810	ENOG4105BZU	Histidine kinase
HN018_RS26835	ENOG4105CW7	secretion protein, HlyD family
HN018_RS26840	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_RS26890	ENOG4105BZU	Histidine kinase
HN018_RS26940	ENOG4105EGS	Mechanosensitive ion channel
HN018_RS27005	ENOG4108V42	Type IV secretion system protein VirB8
HN018_RS27020	ENOG4108EHY	type IV secretion system
HN018_RS27120	ENOG4105WMR	Protein CrcB homolog
HN018_RS27145	ENOG4108BUD	transposase
HN018_RS27165	ENOG4105EEQ	Na H antiporter
HN018_RS27185	ENOG4108YXQ	IS66 Orf2 family protein
HN018_RS27190	ENOG4105E5H	Transposase
HN018_RS27225	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HN018_RS27250	ENOG4108XM1	transcriptional regulator AsnC family
HN018_RS27255	ENOG4108BUD	transposase
HN018_RS27260	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HN018_RS27265	ENOG4108BUD	transposase
HN018_RS27275	ENOG4105BZU	Histidine kinase
HN018_RS27295	ENOG4105EKQ	RNA-directed DNA polymerase
HN018_RS27300	ENOG4108BUD	transposase
HN018_RS27305	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS27335	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HN018_RS27340	ENOG4105C08	Histidine kinase
HN018_RS27345	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HN018_RS27435	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
HN018_RS27490	ENOG4105F5W	AtP-binding protein
HN018_RS27515	ENOG4105CDU	Replicative dna helicase
HN018_RS27565	ENOG4105CHR	reductase
HN018_RS27575	ENOG4105CMT	Dihydroxyacetone kinase
HN018_RS27585	ENOG4105DKT	Transcriptional regulator
HN018_RS27595	ENOG4105C0A	alcohol dehydrogenase
HN018_RS27605	ENOG4105C26	Dehydrogenase
HN018_RS27615	ENOG4105CC0	LysR family Transcriptional regulator
HN018_RS27675	ENOG4105K70	DNA-binding protein
HN018_RS27705	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_RS27740	ENOG4108BUD	transposase
HN018_RS27745	ENOG4105BZU	Histidine kinase
HN018_RS27760	ENOG4105BZU	Histidine kinase
HN018_RS27765	ENOG4108BUD	transposase
HN018_RS27790	ENOG4108HWW	ABC transporter
HN018_RS27795	ENOG4105C2J	ABC transporter
HN018_RS27835	ENOG4105F5W	AtP-binding protein
HN018_RS27845	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_RS27850	ENOG4105E1F	short-chain dehydrogenase reductase
HN018_RS27875	ENOG4105C54	Major Facilitator superfamily
HN018_RS27895	ENOG4105C7H	Helicase, RecD TraA family
HN018_RS27915	ENOG4105BZU	Histidine kinase
HN018_RS27920	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HN018_RS28025	ENOG4105DIA	mandelate racemase muconate lactonizing
HN018_RS28050	ENOG4105EQR	Transposase IS116 IS110 IS902
HN018_RS28115	ENOG4108EHY	type IV secretion system
HN018_RS28170	ENOG4108C33	Resolvase
HN018_RS28190	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
HN018_RS28195	ENOG4107QJE	Chromosome Partitioning Protein
HN018_RS28215	ENOG4108HFV	
HN018_RS28220	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_RS28265	ENOG4105C26	Dehydrogenase
HN018_RS28310	ENOG4105F9F	transposase