locus-tag	class	description
CHL1_RS00005	COG0592	DNA-directed DNA polymerase activity
CHL1_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHL1_RS00020	COG0187	DNA topoisomerase II activity
CHL1_RS00025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHL1_RS00035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHL1_RS00040	COG3414	Phosphotransferase system galactitol-specific IIB component
CHL1_RS00045	COG0534	Mate efflux family protein
CHL1_RS00050	COG1073	alpha beta
CHL1_RS00050	COG2226	methyltransferase
CHL1_RS00055	COG3608	succinylglutamate desuccinylase aspartoacylase
CHL1_RS00060	COG0583	DNA-binding transcription factor activity
CHL1_RS00065	COG0601	transmembrane transport
CHL1_RS00070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHL1_RS00075	COG0747	negative chemotaxis
CHL1_RS00085	COG4608	Belongs to the ABC transporter superfamily
CHL1_RS00100	COG0747	negative chemotaxis
CHL1_RS00105	COG0601	transmembrane transport
CHL1_RS00110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHL1_RS00115	COG0444	Belongs to the ABC transporter superfamily
CHL1_RS00120	COG1124	(ABC) transporter
CHL1_RS00125	COG2119	membrane
CHL1_RS00145	COG2022	thiamine diphosphate biosynthetic process
CHL1_RS00150	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHL1_RS00155	COG0352	thiamine-phosphate diphosphorylase activity
CHL1_RS00160	COG5001	Diguanylate cyclase
CHL1_RS00160	COG3300	MHYT domain
CHL1_RS00175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHL1_RS00175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHL1_RS00190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHL1_RS00205	COG2205	protein histidine kinase activity
CHL1_RS00210	COG0745	RESPONSE REGULATOR receiver
CHL1_RS00230	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_RS00235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHL1_RS00240	COG0095	Lipoate-protein ligase
CHL1_RS00250	COG1393	Belongs to the ArsC family
CHL1_RS00285	COG1741	Belongs to the pirin family
CHL1_RS00320	COG1733	regulation of RNA biosynthetic process
CHL1_RS00325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHL1_RS00330	COG1803	Methylglyoxal synthase
CHL1_RS00340	COG4895	conserved protein (DUF2196)
CHL1_RS00365	COG1737	Transcriptional regulator
CHL1_RS00370	COG1063	alcohol dehydrogenase
CHL1_RS00375	COG1069	ribulokinase activity
CHL1_RS00395	COG1131	(ABC) transporter
CHL1_RS00400	COG0778	Nitroreductase
CHL1_RS00405	COG3706	GGDEF domain
CHL1_RS00410	COG5002	protein histidine kinase activity
CHL1_RS00420	COG0745	RESPONSE REGULATOR receiver
CHL1_RS00445	COG3620	sequence-specific DNA binding
CHL1_RS00450	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
CHL1_RS00500	COG0708	Exodeoxyribonuclease III
CHL1_RS00505	COG0708	Exodeoxyribonuclease III
CHL1_RS00525	COG1132	(ABC) transporter
CHL1_RS00530	COG2207	Transcriptional regulator
CHL1_RS00530	COG3708	Transcriptional regulator
CHL1_RS00545	COG0484	heat shock protein binding
CHL1_RS00565	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_RS00605	COG3383	formate dehydrogenase (NAD+) activity
CHL1_RS00630	COG5002	protein histidine kinase activity
CHL1_RS00630	COG3850	Histidine kinase
CHL1_RS00635	COG1136	(ABC) transporter
CHL1_RS00645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CHL1_RS00660	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_RS00665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_RS00670	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_RS00675	COG0022	dehydrogenase e1 component
CHL1_RS00680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_RS00700	COG2199	diguanylate cyclase activity
CHL1_RS00715	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CHL1_RS00720	COG5001	Diguanylate cyclase
CHL1_RS00725	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_RS00725	COG2199	diguanylate cyclase activity
CHL1_RS00730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHL1_RS00745	COG1233	COG1233 Phytoene dehydrogenase and related
CHL1_RS00750	COG1562	ergosterol biosynthetic process
CHL1_RS00755	COG0170	dolichyl monophosphate biosynthetic process
CHL1_RS00770	COG1063	alcohol dehydrogenase
CHL1_RS00790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHL1_RS00810	COG0004	ammonium transporteR
CHL1_RS00815	COG0347	Belongs to the P(II) protein family
CHL1_RS00840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHL1_RS00850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHL1_RS00855	COG4251	negative regulation of phosphorylation
CHL1_RS00855	COG3706	GGDEF domain
CHL1_RS00855	COG2203	Gaf domain
CHL1_RS00855	COG5001	Diguanylate cyclase
CHL1_RS00860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHL1_RS00880	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CHL1_RS00885	COG1459	type II secretion system
CHL1_RS00920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHL1_RS00925	COG0009	L-threonylcarbamoyladenylate synthase
CHL1_RS00930	COG0698	ribose 5-phosphate isomerase
CHL1_RS00970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHL1_RS00975	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHL1_RS00980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHL1_RS00985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHL1_RS00990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHL1_RS00995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHL1_RS01000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHL1_RS01005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHL1_RS01035	COG1682	transport, permease protein
CHL1_RS01040	COG1134	teichoic acid transport
CHL1_RS01045	COG0438	transferase activity, transferring glycosyl groups
CHL1_RS01045	COG1216	Glycosyl transferase, family 2
CHL1_RS01050	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHL1_RS01140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_RS01145	COG0765	amino acid transport
CHL1_RS01150	COG1126	abc transporter atp-binding protein
CHL1_RS01180	COG1136	(ABC) transporter
CHL1_RS01185	COG0577	efflux transmembrane transporter activity
CHL1_RS01185	COG1136	(ABC) transporter
CHL1_RS01195	COG3850	Histidine kinase
CHL1_RS01195	COG5002	protein histidine kinase activity
CHL1_RS01200	COG2770	Histidine kinase
CHL1_RS01200	COG3437	response regulator, receiver
CHL1_RS01220	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHL1_RS01225	COG1687	branched-chain amino acid
CHL1_RS01235	COG1733	regulation of RNA biosynthetic process
CHL1_RS01245	COG1720	tRNA m6t6A37 methyltransferase activity
CHL1_RS01250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHL1_RS01255	COG0488	(ABC) transporter
CHL1_RS01285	COG0460	homoserine dehydrogenase
CHL1_RS01295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHL1_RS01300	COG0569	domain protein
CHL1_RS01305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHL1_RS01310	COG1459	type II secretion system
CHL1_RS01325	COG0482	sulfurtransferase activity
CHL1_RS01335	COG0745	RESPONSE REGULATOR receiver
CHL1_RS01340	COG3850	Histidine kinase
CHL1_RS01340	COG5002	protein histidine kinase activity
CHL1_RS01360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHL1_RS01370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHL1_RS01375	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CHL1_RS01390	COG1131	(ABC) transporter
CHL1_RS01395	COG0842	Transport permease protein
CHL1_RS01425	COG2267	carboxylic ester hydrolase activity
CHL1_RS01435	COG3304	Inner membrane component domain
CHL1_RS01440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHL1_RS01445	COG2011	ABC-type metal ion transport system permease component
CHL1_RS01450	COG1464	Belongs to the NlpA lipoprotein family
CHL1_RS01455	COG1115	amino acid carrier protein
CHL1_RS01465	COG0745	RESPONSE REGULATOR receiver
CHL1_RS01470	COG5002	protein histidine kinase activity
CHL1_RS01475	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CHL1_RS01485	COG1121	(ABC) transporter
CHL1_RS01490	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CHL1_RS01515	COG1349	DNA-binding transcription factor activity
CHL1_RS01520	COG1105	Belongs to the carbohydrate kinase PfkB family
CHL1_RS01525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHL1_RS01525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHL1_RS01525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_RS01545	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CHL1_RS01565	COG0058	SHG alpha-glucan phosphorylase activity
CHL1_RS01570	COG0366	Alpha amylase catalytic
CHL1_RS01570	COG3103	Sh3 type 3 domain protein
CHL1_RS01580	COG0297	glycogen (starch) synthase activity
CHL1_RS01590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CHL1_RS01595	COG0058	SHG alpha-glucan phosphorylase activity
CHL1_RS01600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHL1_RS01615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHL1_RS01625	COG1307	EDD domain protein, DegV family
CHL1_RS01630	COG2183	response to ionizing radiation
CHL1_RS01635	COG1329	Transcriptional regulator
CHL1_RS01640	COG4956	integral membrane protein (PIN domain superfamily)
CHL1_RS01645	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CHL1_RS01645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHL1_RS01655	COG1683	Conserved Protein
CHL1_RS01660	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHL1_RS01670	COG0018	arginyl-trna synthetase
CHL1_RS01675	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHL1_RS01685	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHL1_RS01690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHL1_RS01695	COG3959	Transketolase, thiamine diphosphate binding domain
CHL1_RS01700	COG3958	Transketolase
CHL1_RS01715	COG1122	ATPase activity
CHL1_RS01720	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHL1_RS01770	COG2378	regulation of single-species biofilm formation
CHL1_RS01785	COG1131	(ABC) transporter
CHL1_RS01820	COG0509	glycine decarboxylation via glycine cleavage system
CHL1_RS01825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHL1_RS01830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHL1_RS01835	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHL1_RS01840	COG1760	l-serine dehydratase
CHL1_RS01845	COG1760	l-serine dehydratase
CHL1_RS01865	COG1522	sequence-specific DNA binding
CHL1_RS01870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHL1_RS01880	COG1309	transcriptional regulator
CHL1_RS01885	COG0840	transmembrane signaling receptor activity
CHL1_RS01895	COG2814	Major facilitator Superfamily
CHL1_RS01900	COG3706	GGDEF domain
CHL1_RS01905	COG0683	leucine binding
CHL1_RS01910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHL1_RS01930	COG1846	Transcriptional regulator
CHL1_RS01935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHL1_RS01940	COG0432	Pfam Uncharacterised protein family UPF0047
CHL1_RS01950	COG1335	isochorismatase
CHL1_RS01955	COG1733	regulation of RNA biosynthetic process
CHL1_RS01985	COG2378	regulation of single-species biofilm formation
CHL1_RS02040	COG0667	Aldo Keto reductase
CHL1_RS02065	COG4115	mRNA cleavage
CHL1_RS02105	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CHL1_RS02110	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CHL1_RS02130	COG0463	Glycosyl transferase, family 2
CHL1_RS02145	COG1082	Xylose isomerase domain protein TIM barrel
CHL1_RS02150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHL1_RS02155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_RS02165	COG1797	cobyrinic acid a,c-diamide synthase activity
CHL1_RS02185	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CHL1_RS02235	COG0745	RESPONSE REGULATOR receiver
CHL1_RS02240	COG5002	protein histidine kinase activity
CHL1_RS02245	COG1136	(ABC) transporter
CHL1_RS02250	COG0577	efflux transmembrane transporter activity
CHL1_RS02255	COG5001	Diguanylate cyclase
CHL1_RS02255	COG3300	MHYT domain
CHL1_RS02260	COG0310	cobalt ion transport
CHL1_RS02275	COG1122	ATPase activity
CHL1_RS02280	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CHL1_RS02285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHL1_RS02285	COG1648	precorrin-2 dehydrogenase activity
CHL1_RS02295	COG0113	porphobilinogen synthase activity
CHL1_RS02300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHL1_RS02325	COG2099	Precorrin-6x reductase
CHL1_RS02330	COG1492	cobalamin metabolic process
CHL1_RS02335	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CHL1_RS02340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHL1_RS02345	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CHL1_RS02390	COG1136	(ABC) transporter
CHL1_RS02410	COG0653	protein targeting
CHL1_RS02435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHL1_RS02440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHL1_RS02450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHL1_RS02460	COG0193	aminoacyl-tRNA hydrolase activity
CHL1_RS02465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHL1_RS02470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHL1_RS02475	COG2244	polysaccharide biosynthetic process
CHL1_RS02480	COG3956	TIGRFAM MazG family protein
CHL1_RS02485	COG0776	regulation of translation
CHL1_RS02490	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHL1_RS02500	COG0248	Ppx GppA phosphatase
CHL1_RS02500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHL1_RS02530	COG0037	tRNA processing
CHL1_RS02535	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CHL1_RS02555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHL1_RS02580	COG0504	CTP synthase activity
CHL1_RS02585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHL1_RS02585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CHL1_RS02595	COG0513	Belongs to the DEAD box helicase family
CHL1_RS02600	COG0534	Mate efflux family protein
CHL1_RS02605	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CHL1_RS02610	COG0215	cysteine-tRNA ligase activity
CHL1_RS02615	COG4496	protein, YerC YecD
CHL1_RS02620	COG0436	Aminotransferase
CHL1_RS02630	COG0802	atpase or kinase
CHL1_RS02635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHL1_RS02640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_RS02645	COG0022	dehydrogenase e1 component
CHL1_RS02645	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_RS02655	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_RS02660	COG0516	GMP reductase activity
CHL1_RS02660	COG0517	IMP dehydrogenase activity
CHL1_RS02725	COG2801	Transposase and inactivated derivatives
CHL1_RS02740	COG2268	Band 7 protein
CHL1_RS02870	COG0281	malic enzyme
CHL1_RS02875	COG0322	excinuclease ABC activity
CHL1_RS02895	COG1131	(ABC) transporter
CHL1_RS02935	COG0697	spore germination
CHL1_RS02995	COG4974	Belongs to the 'phage' integrase family
CHL1_RS03005	COG2176	DNA-directed DNA polymerase activity
CHL1_RS03070	COG3409	Peptidoglycan-binding domain 1 protein
CHL1_RS03070	COG3757	hydrolase, family 25
CHL1_RS03090	COG3383	formate dehydrogenase (NAD+) activity
CHL1_RS03095	COG0746	molybdenum cofactor guanylyltransferase activity
CHL1_RS03130	COG0671	phosphoesterase, PA-phosphatase related
CHL1_RS03135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHL1_RS03145	COG1802	Transcriptional regulator
CHL1_RS03150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHL1_RS03155	COG0628	permease
CHL1_RS03160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHL1_RS03165	COG0124	histidyl-tRNA synthetase
CHL1_RS03170	COG0116	Belongs to the methyltransferase superfamily
CHL1_RS03175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHL1_RS03200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHL1_RS03205	COG1307	EDD domain protein, DegV family
CHL1_RS03220	COG0088	Forms part of the polypeptide exit tunnel
CHL1_RS03225	COG0089	rRNA binding
CHL1_RS03230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHL1_RS03235	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHL1_RS03240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHL1_RS03245	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHL1_RS03250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHL1_RS03255	COG0255	Belongs to the universal ribosomal protein uL29 family
CHL1_RS03260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHL1_RS03265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHL1_RS03275	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHL1_RS03280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHL1_RS03285	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHL1_RS03295	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHL1_RS03300	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHL1_RS03305	COG1841	ribosomal large subunit assembly
CHL1_RS03310	COG0200	Binds to the 23S rRNA
CHL1_RS03315	COG0201	protein transport
CHL1_RS03320	COG0563	adenylate kinase activity
CHL1_RS03335	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHL1_RS03340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHL1_RS03350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHL1_RS03355	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHL1_RS03360	COG0202	RNA polymerase activity
CHL1_RS03370	COG1122	ATPase activity
CHL1_RS03375	COG1122	ATPase activity
CHL1_RS03380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHL1_RS03385	COG0101	tRNA pseudouridine synthase activity
CHL1_RS03390	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHL1_RS03395	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHL1_RS03400	COG1217	gtp-binding protein TYPA
CHL1_RS03410	COG0628	permease
CHL1_RS03440	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CHL1_RS03455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHL1_RS03470	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHL1_RS03480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHL1_RS03485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHL1_RS03495	COG0653	protein targeting
CHL1_RS03500	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHL1_RS03520	COG0646	methionine synthase
CHL1_RS03520	COG1410	methionine synthase
CHL1_RS03530	COG1773	rubredoxin
CHL1_RS03530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHL1_RS03535	COG1309	transcriptional regulator
CHL1_RS03545	COG2204	response regulator
CHL1_RS03550	COG3829	transcription factor binding
CHL1_RS03555	COG5598	trimethylamine methyltransferase
CHL1_RS03560	COG5598	trimethylamine methyltransferase
CHL1_RS03570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_RS03575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHL1_RS03580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHL1_RS03585	COG5012	cobalamin binding
CHL1_RS03600	COG5012	cobalamin binding
CHL1_RS03610	COG0523	cobalamin synthesis protein
CHL1_RS03620	COG0531	amino acid
CHL1_RS03625	COG5001	Diguanylate cyclase
CHL1_RS03630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHL1_RS03645	COG1910	domain protein
CHL1_RS03655	COG0725	ABC transporter, periplasmic molybdate-binding protein
CHL1_RS03660	COG4149	molybdate abc transporter
CHL1_RS03665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHL1_RS03675	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CHL1_RS03695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHL1_RS03720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHL1_RS03725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHL1_RS03730	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CHL1_RS03745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_RS03750	COG0022	dehydrogenase e1 component
CHL1_RS03755	COG3199	ATP-NAD kinase
CHL1_RS03760	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_RS03765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_RS03775	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHL1_RS03790	COG0598	Magnesium transport protein CorA
CHL1_RS03815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHL1_RS03840	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHL1_RS03885	COG0739	heme binding
CHL1_RS03885	COG0741	lytic transglycosylase activity
CHL1_RS03885	COG1196	nuclear chromosome segregation
CHL1_RS03950	COG5484	DNA packaging
CHL1_RS04095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHL1_RS04105	COG0582	viral genome integration into host DNA
CHL1_RS04115	COG1151	hydroxylamine reductase activity
CHL1_RS04130	COG4717	serine-type aminopeptidase activity
CHL1_RS04145	COG2878	Part of a membrane complex involved in electron transport
CHL1_RS04185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHL1_RS04190	COG1040	competence protein
CHL1_RS04205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CHL1_RS04210	COG1660	Displays ATPase and GTPase activities
CHL1_RS04215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CHL1_RS04220	COG1481	regulation of sporulation
CHL1_RS04250	COG0840	transmembrane signaling receptor activity
CHL1_RS04280	COG4974	Belongs to the 'phage' integrase family
CHL1_RS04285	COG2003	Belongs to the UPF0758 family
CHL1_RS04300	COG4974	Belongs to the 'phage' integrase family
CHL1_RS04330	COG1484	DNA-dependent DNA replication
CHL1_RS04365	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHL1_RS04370	COG2365	Tyrosine phosphatase family
CHL1_RS04375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHL1_RS04380	COG1420	regulation of RNA biosynthetic process
CHL1_RS04385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHL1_RS04390	COG0443	Heat shock 70 kDa protein
CHL1_RS04395	COG0484	heat shock protein binding
CHL1_RS04400	COG1959	2 iron, 2 sulfur cluster binding
CHL1_RS04410	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CHL1_RS04415	COG4917	ethanolamine utilization protein
CHL1_RS04425	COG2264	protein methyltransferase activity
CHL1_RS04430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHL1_RS04435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHL1_RS04440	COG0537	adenosine 5'-monophosphoramidase activity
CHL1_RS04445	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHL1_RS04450	COG1610	YqeY-like protein
CHL1_RS04455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHL1_RS04490	COG2137	regulation of response to DNA damage stimulus
CHL1_RS04505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHL1_RS04575	COG3845	ABC transporter
CHL1_RS04580	COG4603	Belongs to the binding-protein-dependent transport system permease family
CHL1_RS04585	COG1079	Belongs to the binding-protein-dependent transport system permease family
CHL1_RS04595	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHL1_RS04600	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHL1_RS04615	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CHL1_RS04625	COG1366	Belongs to the anti-sigma-factor antagonist family
CHL1_RS04650	COG0189	ligase activity
CHL1_RS04655	COG0189	ligase activity
CHL1_RS04665	COG5001	Diguanylate cyclase
CHL1_RS04665	COG4251	negative regulation of phosphorylation
CHL1_RS04665	COG3706	GGDEF domain
CHL1_RS04665	COG2203	Gaf domain
CHL1_RS04675	COG2972	Histidine kinase
CHL1_RS04680	COG2201	protein-glutamate methylesterase activity
CHL1_RS04725	COG4869	propanediol catabolic process
CHL1_RS04740	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CHL1_RS04780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHL1_RS04785	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHL1_RS04790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHL1_RS04795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHL1_RS04800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_RS04815	COG1366	Belongs to the anti-sigma-factor antagonist family
CHL1_RS04820	COG2172	sigma factor antagonist activity
CHL1_RS04825	COG1191	sigma factor activity
CHL1_RS04830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHL1_RS04840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHL1_RS04850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CHL1_RS04855	COG1074	ATP-dependent DNA helicase activity
CHL1_RS04895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHL1_RS04915	COG4589	Belongs to the CDS family
CHL1_RS04920	COG0750	zinc metalloprotease
CHL1_RS04925	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHL1_RS04935	COG2176	DNA-directed DNA polymerase activity
CHL1_RS04950	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHL1_RS04955	COG1454	alcohol dehydrogenase
CHL1_RS04960	COG0741	lytic transglycosylase activity
CHL1_RS04960	COG0739	heme binding
CHL1_RS04960	COG1196	nuclear chromosome segregation
CHL1_RS04965	COG2884	Cell division ATP-binding protein ftsE
CHL1_RS04970	COG2177	Part of the ABC transporter FtsEX involved in
CHL1_RS04975	COG0739	heme binding
CHL1_RS04975	COG0741	lytic transglycosylase activity
CHL1_RS04975	COG1196	nuclear chromosome segregation
CHL1_RS04980	COG3409	Peptidoglycan-binding domain 1 protein
CHL1_RS04980	COG0793	Belongs to the peptidase S41A family
CHL1_RS04985	COG0556	nucleotide-excision repair
CHL1_RS05000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CHL1_RS05015	COG1278	Cold shock
CHL1_RS05025	COG0322	excinuclease ABC activity
CHL1_RS05030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CHL1_RS05045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHL1_RS05055	COG0423	glycine-tRNA ligase activity
CHL1_RS05060	COG1283	sodium-dependent phosphate transmembrane transporter activity
CHL1_RS05070	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CHL1_RS05100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHL1_RS05105	COG1776	CheC inhibitor of MCP methylation
CHL1_RS05105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHL1_RS05115	COG2201	protein-glutamate methylesterase activity
CHL1_RS05120	COG1338	Plays a role in the flagellum-specific transport system
CHL1_RS05120	COG3190	flagellar
CHL1_RS05125	COG1338	Plays a role in the flagellum-specific transport system
CHL1_RS05135	COG1684	flagellar biosynthetic protein fliR
CHL1_RS05140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHL1_RS05145	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHL1_RS05150	COG1191	sigma factor activity
CHL1_RS05155	COG4786	Flagellar basal body rod
CHL1_RS05160	COG4786	Flagellar basal body rod
CHL1_RS05170	COG1776	CheC inhibitor of MCP methylation
CHL1_RS05175	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CHL1_RS05180	COG0835	chemotaxis
CHL1_RS05185	COG2201	protein-glutamate methylesterase activity
CHL1_RS05200	COG4786	Flagellar basal body rod
CHL1_RS05200	COG1256	bacterial-type flagellum assembly
CHL1_RS05205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHL1_RS05220	COG0463	Glycosyl transferase, family 2
CHL1_RS05245	COG1216	Glycosyl transferase, family 2
CHL1_RS05250	COG0110	maltose O-acetyltransferase activity
CHL1_RS05260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_RS05270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_RS05280	COG1216	Glycosyl transferase, family 2
CHL1_RS05280	COG1442	glycosyl transferase family 8
CHL1_RS05290	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHL1_RS05310	COG2198	Histidine kinase
CHL1_RS05310	COG0643	Histidine kinase
CHL1_RS05320	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CHL1_RS05335	COG1815	bacterial-type flagellum-dependent cell motility
CHL1_RS05340	COG1558	bacterial-type flagellum-dependent cell motility
CHL1_RS05345	COG1677	Flagellar hook-basal body complex protein FliE
CHL1_RS05355	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHL1_RS05365	COG1157	protein secretion by the type III secretion system
CHL1_RS05380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CHL1_RS05390	COG2390	Transcriptional regulator
CHL1_RS05400	COG0126	phosphoglycerate kinase activity
CHL1_RS05410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CHL1_RS05415	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHL1_RS05430	COG0542	response to heat
CHL1_RS05445	COG0166	Belongs to the GPI family
CHL1_RS05450	COG3300	MHYT domain
CHL1_RS05450	COG5001	Diguanylate cyclase
CHL1_RS05465	COG0473	3-isopropylmalate dehydrogenase activity
CHL1_RS05475	COG1522	sequence-specific DNA binding
CHL1_RS05480	COG0686	Belongs to the AlaDH PNT family
CHL1_RS05485	COG1115	amino acid carrier protein
CHL1_RS05490	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHL1_RS05490	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHL1_RS05490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHL1_RS05490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL1_RS05500	COG0358	DNA primase activity
CHL1_RS05505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHL1_RS05510	COG2384	SAM-dependent methyltransferase
CHL1_RS05515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CHL1_RS05525	COG2204	response regulator
CHL1_RS05535	COG5564	TIM-barrel signal transduction protein
CHL1_RS05540	COG1070	Carbohydrate kinase
CHL1_RS05550	COG0745	RESPONSE REGULATOR receiver
CHL1_RS05570	COG1477	protein flavinylation
CHL1_RS05580	COG2226	methyltransferase
CHL1_RS05665	COG1937	Protein conserved in bacteria
CHL1_RS05675	COG2217	Heavy metal translocating P-type atpase
CHL1_RS05720	COG1394	ATPase activity, coupled to movement of substances
CHL1_RS05775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHL1_RS05820	COG5012	cobalamin binding
CHL1_RS05825	COG0840	transmembrane signaling receptor activity
CHL1_RS05830	COG0583	DNA-binding transcription factor activity
CHL1_RS05835	COG0583	DNA-binding transcription factor activity
CHL1_RS05860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHL1_RS05890	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_RS05895	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL1_RS05900	COG2414	aldehyde ferredoxin oxidoreductase
CHL1_RS05905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CHL1_RS05935	COG2508	Transcriptional regulator
CHL1_RS05955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHL1_RS05965	COG0601	transmembrane transport
CHL1_RS05970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHL1_RS05975	COG0444	Belongs to the ABC transporter superfamily
CHL1_RS05980	COG1124	(ABC) transporter
CHL1_RS05985	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHL1_RS05990	COG0573	inorganic phosphate transmembrane transporter activity
CHL1_RS06000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHL1_RS06005	COG0704	Plays a role in the regulation of phosphate uptake
CHL1_RS06015	COG3706	GGDEF domain
CHL1_RS06025	COG0840	transmembrane signaling receptor activity
CHL1_RS06080	COG2212	antiporter activity
CHL1_RS06090	COG0840	transmembrane signaling receptor activity
CHL1_RS06095	COG0840	transmembrane signaling receptor activity
CHL1_RS06100	COG1842	Phage shock protein A
CHL1_RS06110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHL1_RS06120	COG3300	MHYT domain
CHL1_RS06120	COG5001	Diguanylate cyclase
CHL1_RS06135	COG2217	Heavy metal translocating P-type atpase
CHL1_RS06140	COG0789	Transcriptional regulator
CHL1_RS06150	COG1131	(ABC) transporter
CHL1_RS06155	COG3237	CsbD-like
CHL1_RS06160	COG3942	CHAP domain
CHL1_RS06160	COG1388	LysM domain
CHL1_RS06165	COG0306	phosphate transporter
CHL1_RS06180	COG3706	GGDEF domain
CHL1_RS06185	COG3437	response regulator, receiver
CHL1_RS06185	COG0784	Response regulator, receiver
CHL1_RS06200	COG1408	metallophosphoesterase
CHL1_RS06210	COG0003	Pfam Anion-transporting ATPase
CHL1_RS06220	COG0003	Pfam Anion-transporting ATPase
CHL1_RS06225	COG3426	butyrate kinase activity
CHL1_RS06230	COG2309	aminopeptidase activity
CHL1_RS06235	COG0840	transmembrane signaling receptor activity
CHL1_RS06275	COG1595	DNA-templated transcription, initiation
CHL1_RS06290	COG0840	transmembrane signaling receptor activity
CHL1_RS06295	COG0840	transmembrane signaling receptor activity
CHL1_RS06305	COG5001	Diguanylate cyclase
CHL1_RS06305	COG1716	ATPase activity
CHL1_RS06310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHL1_RS06330	COG1732	Glycine betaine
CHL1_RS06335	COG0517	IMP dehydrogenase activity
CHL1_RS06335	COG1125	glycine betaine transport
CHL1_RS06355	COG0765	amino acid transport
CHL1_RS06360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_RS06370	COG3620	sequence-specific DNA binding
CHL1_RS06380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHL1_RS06385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHL1_RS06390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHL1_RS06395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHL1_RS06420	COG3706	GGDEF domain
CHL1_RS06445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHL1_RS06450	COG3706	GGDEF domain
CHL1_RS06460	COG0071	Belongs to the small heat shock protein (HSP20) family
CHL1_RS06465	COG0348	domain, Protein
CHL1_RS06485	COG2827	Endonuclease containing a URI domain
CHL1_RS06490	COG0732	type I restriction modification DNA specificity domain
CHL1_RS06530	COG4824	toxin secretion phage lysis holin
CHL1_RS06570	COG0789	Transcriptional regulator
CHL1_RS06575	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_RS06575	COG1902	pentaerythritol trinitrate reductase activity
CHL1_RS06600	COG3290	protein histidine kinase activity
CHL1_RS06600	COG3829	transcription factor binding
CHL1_RS06635	COG5012	cobalamin binding
CHL1_RS06660	COG2188	Transcriptional regulator
CHL1_RS06695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHL1_RS06715	COG3706	GGDEF domain
CHL1_RS06745	COG0789	Transcriptional regulator
CHL1_RS06750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHL1_RS06755	COG0066	3-isopropylmalate dehydratase activity
CHL1_RS06775	COG0784	Response regulator, receiver
CHL1_RS06775	COG2205	protein histidine kinase activity
CHL1_RS06775	COG5002	protein histidine kinase activity
CHL1_RS06790	COG0596	Alpha beta hydrolase
CHL1_RS06795	COG3706	GGDEF domain
CHL1_RS06830	COG0789	Transcriptional regulator
CHL1_RS06840	COG2226	methyltransferase
CHL1_RS06850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHL1_RS06865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHL1_RS06900	COG0840	transmembrane signaling receptor activity
CHL1_RS06935	COG2814	Major facilitator Superfamily
CHL1_RS06940	COG0488	(ABC) transporter
CHL1_RS06950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHL1_RS06955	COG0275	rRNA processing
CHL1_RS07030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHL1_RS07035	COG1131	(ABC) transporter
CHL1_RS07045	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHL1_RS07055	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CHL1_RS07060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHL1_RS07065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHL1_RS07070	COG0284	orotidine-5'-phosphate decarboxylase activity
CHL1_RS07075	COG0543	2 iron, 2 sulfur cluster binding
CHL1_RS07080	COG0167	dihydroorotate dehydrogenase activity
CHL1_RS07085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHL1_RS07090	COG0693	protein deglycase activity
CHL1_RS07095	COG2203	Gaf domain
CHL1_RS07095	COG3706	GGDEF domain
CHL1_RS07095	COG4251	negative regulation of phosphorylation
CHL1_RS07095	COG5001	Diguanylate cyclase
CHL1_RS07120	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_RS07120	COG2199	diguanylate cyclase activity
CHL1_RS07125	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_RS07130	COG0840	transmembrane signaling receptor activity
CHL1_RS07135	COG0840	transmembrane signaling receptor activity
CHL1_RS07155	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CHL1_RS07170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHL1_RS07175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHL1_RS07180	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHL1_RS07185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHL1_RS07190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHL1_RS07195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHL1_RS07200	COG0138	bifunctional purine biosynthesis protein purh
CHL1_RS07205	COG0151	Belongs to the GarS family
CHL1_RS07210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHL1_RS07215	COG1472	Belongs to the glycosyl hydrolase 3 family
CHL1_RS07220	COG1214	PFAM Peptidase M22, glycoprotease
CHL1_RS07235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHL1_RS07245	COG0459	protein refolding
CHL1_RS07255	COG0488	(ABC) transporter
CHL1_RS07260	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CHL1_RS07265	COG1396	sequence-specific DNA binding
CHL1_RS07290	COG2333	competence protein COMEC
CHL1_RS07290	COG0658	competence protein
CHL1_RS07295	COG1466	dna polymerase III delta subunit
CHL1_RS07300	COG0268	Binds directly to 16S ribosomal RNA
CHL1_RS07305	COG0481	GTPase activity
CHL1_RS07315	COG2376	Dihydroxyacetone kinase
CHL1_RS07335	COG1349	DNA-binding transcription factor activity
CHL1_RS07345	COG5012	cobalamin binding
CHL1_RS07360	COG2376	Dihydroxyacetone kinase
CHL1_RS07385	COG1704	LemA family
CHL1_RS07410	COG3457	Alanine racemase
CHL1_RS07415	COG0495	leucyl-tRNA aminoacylation
CHL1_RS07445	COG1242	4 iron, 4 sulfur cluster binding
CHL1_RS07450	COG2357	RelA SpoT domain protein
CHL1_RS07455	COG0217	transcriptional regulatory protein
CHL1_RS07465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHL1_RS07465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHL1_RS07470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHL1_RS07500	COG3620	sequence-specific DNA binding
CHL1_RS07515	COG3617	BRO family, N-terminal domain
CHL1_RS07525	COG1396	sequence-specific DNA binding
CHL1_RS07575	COG0629	single-stranded DNA binding
CHL1_RS07585	COG1484	DNA-dependent DNA replication
CHL1_RS07680	COG3728	DNA packaging
CHL1_RS07680	COG5484	DNA packaging
CHL1_RS07745	COG2801	Transposase and inactivated derivatives
CHL1_RS07840	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHL1_RS07875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHL1_RS07880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHL1_RS07885	COG0557	exoribonuclease II activity
CHL1_RS07890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHL1_RS07930	COG3706	GGDEF domain
CHL1_RS07935	COG2199	diguanylate cyclase activity
CHL1_RS07935	COG2203	Gaf domain
CHL1_RS07940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHL1_RS07945	COG2508	Transcriptional regulator
CHL1_RS07945	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CHL1_RS07960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHL1_RS07965	COG1454	alcohol dehydrogenase
CHL1_RS07970	COG1396	sequence-specific DNA binding
CHL1_RS07975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHL1_RS07980	COG0531	amino acid
CHL1_RS07985	COG1454	alcohol dehydrogenase
CHL1_RS08005	COG2200	EAL domain
CHL1_RS08040	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CHL1_RS08045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CHL1_RS08060	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CHL1_RS08065	COG1301	dicarboxylic acid transport
CHL1_RS08090	COG5001	Diguanylate cyclase
CHL1_RS08090	COG3300	MHYT domain
CHL1_RS08095	COG1966	Carbon starvation protein
CHL1_RS08100	COG3527	Alpha-acetolactate decarboxylase
CHL1_RS08105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHL1_RS08110	COG0697	spore germination
CHL1_RS08125	COG0425	Belongs to the sulfur carrier protein TusA family
CHL1_RS08130	COG2210	Belongs to the sulfur carrier protein TusA family
CHL1_RS08135	COG1104	cysteine desulfurase activity
CHL1_RS08155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHL1_RS08160	COG4399	Belongs to the UPF0754 family
CHL1_RS08175	COG1136	(ABC) transporter
CHL1_RS08190	COG0500	methyltransferase
CHL1_RS08200	COG1757	Na H antiporter
CHL1_RS08220	COG1115	amino acid carrier protein
CHL1_RS08230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHL1_RS08235	COG2868	ribosomal protein
CHL1_RS08240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHL1_RS08245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHL1_RS08255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHL1_RS08260	COG1713	HD superfamily hydrolase involved in NAD metabolism
CHL1_RS08265	COG0799	negative regulation of ribosome biogenesis
CHL1_RS08270	COG0012	GTP binding
CHL1_RS08280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHL1_RS08290	COG4120	Belongs to the binding-protein-dependent transport system permease family
CHL1_RS08295	COG3842	ATPase activity
CHL1_RS08300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHL1_RS08315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHL1_RS08320	COG0569	domain protein
CHL1_RS08325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHL1_RS08330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHL1_RS08335	COG0072	phenylalanine-tRNA ligase activity
CHL1_RS08335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHL1_RS08355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHL1_RS08360	COG4974	Belongs to the 'phage' integrase family
CHL1_RS08385	COG2217	Heavy metal translocating P-type atpase
CHL1_RS08425	COG0701	Predicted permease
CHL1_RS08430	COG0640	Transcriptional regulator
CHL1_RS08470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_RS08475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHL1_RS08495	COG0509	glycine decarboxylation via glycine cleavage system
CHL1_RS08510	COG0640	Transcriptional regulator
CHL1_RS08515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHL1_RS08520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHL1_RS08555	COG1126	abc transporter atp-binding protein
CHL1_RS08560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_RS08565	COG0765	amino acid transport
CHL1_RS08570	COG0765	amino acid transport
CHL1_RS08585	COG3706	GGDEF domain
CHL1_RS08600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHL1_RS08635	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CHL1_RS08670	COG0525	valine-tRNA ligase activity
CHL1_RS08675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHL1_RS08690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHL1_RS08695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHL1_RS08720	COG0372	Belongs to the citrate synthase family
CHL1_RS08735	COG1692	metallophosphoesterase
CHL1_RS08740	COG1418	mRNA catabolic process
CHL1_RS08745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHL1_RS08750	COG1546	Belongs to the CinA family
CHL1_RS08750	COG1058	Belongs to the CinA family
CHL1_RS08755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHL1_RS08760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHL1_RS08765	COG1674	ftsk spoiiie
CHL1_RS08770	COG0756	dUTP diphosphatase activity
CHL1_RS08775	COG1185	polyribonucleotide nucleotidyltransferase activity
CHL1_RS08780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHL1_RS08785	COG0196	riboflavin kinase activity
CHL1_RS08790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHL1_RS08795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CHL1_RS08800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHL1_RS08805	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHL1_RS08810	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CHL1_RS08815	COG0195	Participates in both transcription termination and antitermination
CHL1_RS08820	COG0779	Required for maturation of 30S ribosomal subunits
CHL1_RS08825	COG0233	cytoplasmic translational termination
CHL1_RS08830	COG0528	UMP kinase activity
CHL1_RS08835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHL1_RS08840	COG0052	Belongs to the universal ribosomal protein uS2 family
CHL1_RS08845	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHL1_RS08850	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHL1_RS08855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHL1_RS08860	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CHL1_RS08865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHL1_RS08870	COG0758	DNA mediated transformation
CHL1_RS08875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_RS08910	COG2894	cell division
CHL1_RS08965	COG5001	Diguanylate cyclase
CHL1_RS08965	COG3300	MHYT domain
CHL1_RS08980	COG1381	Involved in DNA repair and RecF pathway recombination
CHL1_RS08985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHL1_RS08990	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CHL1_RS08995	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHL1_RS09020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHL1_RS09025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHL1_RS09035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHL1_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_RS09045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHL1_RS09050	COG0511	ligase activity, forming carbon-carbon bonds
CHL1_RS09060	COG0439	Biotin carboxylase
CHL1_RS09065	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHL1_RS09070	COG0825	malonyl-CoA metabolic process
CHL1_RS09090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHL1_RS09095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHL1_RS09120	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_RS09130	COG1846	Transcriptional regulator
CHL1_RS09135	COG0386	Belongs to the glutathione peroxidase family
CHL1_RS09145	COG3706	GGDEF domain
CHL1_RS09170	COG0745	RESPONSE REGULATOR receiver
CHL1_RS09175	COG2205	protein histidine kinase activity
CHL1_RS09175	COG3437	response regulator, receiver
CHL1_RS09175	COG3850	Histidine kinase
CHL1_RS09175	COG4999	Histidine kinase
CHL1_RS09190	COG0835	chemotaxis
CHL1_RS09195	COG2198	Histidine kinase
CHL1_RS09195	COG0643	Histidine kinase
CHL1_RS09210	COG2207	Transcriptional regulator
CHL1_RS09210	COG3708	Transcriptional regulator
CHL1_RS09230	COG3041	Addiction module toxin RelE StbE family
CHL1_RS09255	COG4584	PFAM Integrase catalytic
CHL1_RS09290	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CHL1_RS09295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_RS09305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHL1_RS09310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHL1_RS09315	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHL1_RS09335	COG3706	GGDEF domain
CHL1_RS09345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHL1_RS09365	COG1744	ABC transporter substrate-binding protein PnrA-like
CHL1_RS09375	COG3706	GGDEF domain
CHL1_RS09450	COG0494	nUDIX hydrolase
CHL1_RS09470	COG0556	nucleotide-excision repair
CHL1_RS09515	COG2198	Histidine kinase
CHL1_RS09515	COG5002	protein histidine kinase activity
CHL1_RS09515	COG0784	Response regulator, receiver
CHL1_RS09520	COG2003	Belongs to the UPF0758 family
CHL1_RS09560	COG0428	transporter
CHL1_RS09570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHL1_RS09570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_RS09570	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CHL1_RS09580	COG2376	Dihydroxyacetone kinase
CHL1_RS09585	COG0159	tryptophan synthase activity
CHL1_RS09590	COG0133	tryptophan synthase activity
CHL1_RS09600	COG0134	indole-3-glycerol-phosphate synthase activity
CHL1_RS09605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHL1_RS09610	COG0512	Glutamine amidotransferase of anthranilate synthase
CHL1_RS09610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHL1_RS09630	COG1162	GTPase activity
CHL1_RS09635	COG1695	Transcriptional regulator
CHL1_RS09650	COG0840	transmembrane signaling receptor activity
CHL1_RS09660	COG2201	protein-glutamate methylesterase activity
CHL1_RS09665	COG0513	Belongs to the DEAD box helicase family
CHL1_RS09675	COG1278	Cold shock
CHL1_RS09690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHL1_RS09705	COG0514	ATP-dependent DNA helicase (RecQ)
CHL1_RS09725	COG0424	maF-like protein
CHL1_RS09730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHL1_RS09740	COG0025	NhaP-type Na H and K H
CHL1_RS09745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHL1_RS09810	COG0688	phosphatidylethanolamine metabolic process
CHL1_RS09820	COG3706	GGDEF domain
CHL1_RS09825	COG3706	GGDEF domain
CHL1_RS09840	COG0259	pyridoxamine-phosphate oxidase activity
CHL1_RS09845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHL1_RS09855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CHL1_RS09865	COG2188	Transcriptional regulator
CHL1_RS09880	COG0784	Response regulator, receiver
CHL1_RS09880	COG3437	response regulator, receiver
CHL1_RS09900	COG2176	DNA-directed DNA polymerase activity
CHL1_RS09905	COG3706	GGDEF domain
CHL1_RS09925	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_RS09930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHL1_RS09935	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_RS09940	COG1070	Carbohydrate kinase
CHL1_RS09950	COG0596	Alpha beta hydrolase
CHL1_RS09975	COG1151	hydroxylamine reductase activity
CHL1_RS10000	COG2909	trisaccharide binding
CHL1_RS10005	COG0488	(ABC) transporter
CHL1_RS10010	COG0326	Molecular chaperone. Has ATPase activity
CHL1_RS10015	COG0436	Aminotransferase
CHL1_RS10040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHL1_RS10045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHL1_RS10050	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CHL1_RS10055	COG1067	ATP-dependent peptidase activity
CHL1_RS10075	COG4443	Transcriptional Coactivator p15 (PC4)
CHL1_RS10080	COG1475	DNA binding
CHL1_RS10125	COG0840	transmembrane signaling receptor activity
CHL1_RS10130	COG0840	transmembrane signaling receptor activity
CHL1_RS10135	COG0840	transmembrane signaling receptor activity
CHL1_RS10160	COG2364	Membrane
CHL1_RS10165	COG3447	MASE1 domain protein
CHL1_RS10165	COG5001	Diguanylate cyclase
CHL1_RS10165	COG5002	protein histidine kinase activity
CHL1_RS10180	COG0488	(ABC) transporter
CHL1_RS10185	COG3119	arylsulfatase activity
CHL1_RS10190	COG0641	radical SAM
CHL1_RS10200	COG3944	biosynthesis protein
CHL1_RS10205	COG1316	TRANSCRIPTIONal
CHL1_RS10210	COG1086	Polysaccharide biosynthesis protein
CHL1_RS10240	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CHL1_RS10260	COG2244	polysaccharide biosynthetic process
CHL1_RS10265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHL1_RS10275	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CHL1_RS10300	COG0438	transferase activity, transferring glycosyl groups
CHL1_RS10305	COG0438	transferase activity, transferring glycosyl groups
CHL1_RS10345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHL1_RS10350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHL1_RS10365	COG0792	nuclease activity
CHL1_RS10370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHL1_RS10380	COG0681	Belongs to the peptidase S26 family
CHL1_RS10385	COG0335	large ribosomal subunit rRNA binding
CHL1_RS10390	COG0336	Belongs to the RNA methyltransferase TrmD family
CHL1_RS10395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHL1_RS10400	COG1837	Belongs to the UPF0109 family
CHL1_RS10405	COG0228	four-way junction DNA binding
CHL1_RS10410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHL1_RS10415	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CHL1_RS10420	COG0552	protein localization to endoplasmic reticulum
CHL1_RS10425	COG1196	nuclear chromosome segregation
CHL1_RS10430	COG1196	nuclear chromosome segregation
CHL1_RS10440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHL1_RS10445	COG0416	fatty acid biosynthetic process
CHL1_RS10450	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CHL1_RS10460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHL1_RS10470	COG2272	Belongs to the type-B carboxylesterase lipase family
CHL1_RS10490	COG0563	adenylate kinase activity
CHL1_RS10500	COG4086	secreted protein
CHL1_RS10515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL1_RS10515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL1_RS10520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL1_RS10520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL1_RS10525	COG1476	TRANSCRIPTIONal
CHL1_RS10555	COG0440	acetolactate synthase activity
CHL1_RS10560	COG3962	Belongs to the TPP enzyme family
CHL1_RS10565	COG0028	Belongs to the TPP enzyme family
CHL1_RS10585	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHL1_RS10590	COG0742	ribosomal rna small subunit methyltransferase
CHL1_RS10595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHL1_RS10600	COG1461	Dihydroxyacetone kinase
CHL1_RS10605	COG1302	Protein conserved in bacteria
CHL1_RS10610	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHL1_RS10620	COG1162	GTPase activity
CHL1_RS10625	COG2815	serine threonine protein kinase
CHL1_RS10625	COG0515	serine threonine protein kinase
CHL1_RS10630	COG0631	protein serine/threonine phosphatase activity
CHL1_RS10635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHL1_RS10640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHL1_RS10640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHL1_RS10645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHL1_RS10645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHL1_RS10650	COG2738	Putative neutral zinc metallopeptidase
CHL1_RS10655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHL1_RS10660	COG0242	peptide deformylase activity
CHL1_RS10665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHL1_RS10680	COG1561	YicC-like family, N-terminal region
CHL1_RS10690	COG0564	pseudouridine synthase activity
CHL1_RS10700	COG1799	cell septum assembly
CHL1_RS10710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHL1_RS10735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHL1_RS10750	COG1215	transferase activity, transferring glycosyl groups
CHL1_RS10770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHL1_RS10775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHL1_RS10780	COG1490	D-aminoacyl-tRNA deacylase activity
CHL1_RS10785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHL1_RS10795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CHL1_RS10795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHL1_RS10800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHL1_RS10805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHL1_RS10810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHL1_RS10815	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHL1_RS10820	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHL1_RS10825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHL1_RS10835	COG0740	serine-type endopeptidase activity
CHL1_RS10840	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHL1_RS10850	COG0411	ABC transporter
CHL1_RS10860	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHL1_RS10865	COG0683	leucine binding
CHL1_RS10870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHL1_RS10875	COG0662	Cupin 2, conserved barrel domain protein
CHL1_RS10880	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHL1_RS10885	COG0564	pseudouridine synthase activity
CHL1_RS10890	COG2878	Part of a membrane complex involved in electron transport
CHL1_RS10890	COG1245	4Fe-4S binding domain
CHL1_RS10895	COG4657	Part of a membrane complex involved in electron transport
CHL1_RS10900	COG4660	Part of a membrane complex involved in electron transport
CHL1_RS10905	COG4659	FMN binding
CHL1_RS10910	COG4658	electron transport chain
CHL1_RS10915	COG4656	Part of a membrane complex involved in electron transport
CHL1_RS10920	COG1362	aminopeptidase activity
CHL1_RS10925	COG4224	UPF0291 protein
CHL1_RS10930	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CHL1_RS10935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHL1_RS10940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHL1_RS10950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHL1_RS10955	COG1846	Transcriptional regulator
CHL1_RS10955	COG0456	acetyltransferase
CHL1_RS10960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHL1_RS10975	COG2610	gluconate transmembrane transporter activity
CHL1_RS11005	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CHL1_RS11010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHL1_RS11015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHL1_RS11025	COG0131	Imidazoleglycerol-phosphate dehydratase
CHL1_RS11030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHL1_RS11035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHL1_RS11040	COG0107	imidazoleglycerol-phosphate synthase activity
CHL1_RS11045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CHL1_RS11045	COG0140	phosphoribosyl-ATP diphosphatase activity
CHL1_RS11065	COG2414	aldehyde ferredoxin oxidoreductase
CHL1_RS11070	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHL1_RS11070	COG2918	glutathione biosynthetic process
CHL1_RS11100	COG1842	Phage shock protein A
CHL1_RS11115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHL1_RS11120	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_RS11150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHL1_RS11155	COG0300	oxidoreductase activity
CHL1_RS11215	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CHL1_RS11250	COG0248	Ppx GppA phosphatase
CHL1_RS11255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CHL1_RS11265	COG1811	Na channel or pump
CHL1_RS11275	COG1940	carbohydrate kinase activity
CHL1_RS11285	COG0577	efflux transmembrane transporter activity
CHL1_RS11295	COG1136	(ABC) transporter
CHL1_RS11305	COG1131	(ABC) transporter
CHL1_RS11310	COG1725	Transcriptional regulator
CHL1_RS11315	COG0840	transmembrane signaling receptor activity
CHL1_RS11325	COG0142	geranyltranstransferase activity
CHL1_RS11330	COG1252	NADH dehydrogenase
CHL1_RS11350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHL1_RS11355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CHL1_RS11360	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL1_RS11370	COG0321	lipoyl(octanoyl) transferase activity
CHL1_RS11375	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_RS11390	COG1691	(AIR) carboxylase
CHL1_RS11395	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CHL1_RS11400	COG0840	transmembrane signaling receptor activity
CHL1_RS11400	COG3290	protein histidine kinase activity
CHL1_RS11420	COG1606	tRNA processing
CHL1_RS11425	COG0519	Catalyzes the synthesis of GMP from XMP
CHL1_RS11435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHL1_RS11440	COG2011	ABC-type metal ion transport system permease component
CHL1_RS11450	COG1144	Oxidoreductase
CHL1_RS11455	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHL1_RS11460	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHL1_RS11470	COG0436	Aminotransferase
CHL1_RS11475	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CHL1_RS11480	COG0626	cystathionine gamma-synthase activity
CHL1_RS11490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHL1_RS11500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHL1_RS11505	COG0626	cystathionine gamma-synthase activity
CHL1_RS11510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHL1_RS11515	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CHL1_RS11525	COG2871	sodium ion transport
CHL1_RS11530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHL1_RS11550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHL1_RS11555	COG5012	cobalamin binding
CHL1_RS11560	COG1959	2 iron, 2 sulfur cluster binding
CHL1_RS11580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHL1_RS11595	COG2205	protein histidine kinase activity
CHL1_RS11600	COG2608	mercury ion transmembrane transporter activity
CHL1_RS11615	COG2217	Heavy metal translocating P-type atpase
CHL1_RS11630	COG3608	succinylglutamate desuccinylase aspartoacylase
CHL1_RS11630	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHL1_RS11645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHL1_RS11650	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHL1_RS11655	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CHL1_RS11660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_RS11745	COG5001	Diguanylate cyclase
CHL1_RS11745	COG3447	MASE1 domain protein
CHL1_RS11745	COG5002	protein histidine kinase activity
CHL1_RS11760	COG0745	RESPONSE REGULATOR receiver
CHL1_RS11765	COG0784	Response regulator, receiver
CHL1_RS11765	COG2205	protein histidine kinase activity
CHL1_RS11770	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CHL1_RS11775	COG2201	protein-glutamate methylesterase activity
CHL1_RS11780	COG0840	transmembrane signaling receptor activity
CHL1_RS11785	COG0835	chemotaxis
CHL1_RS11790	COG0643	Histidine kinase
CHL1_RS11790	COG2198	Histidine kinase
CHL1_RS11800	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CHL1_RS11825	COG2211	Major facilitator Superfamily
CHL1_RS11835	COG5012	cobalamin binding
CHL1_RS11840	COG2211	Major facilitator Superfamily
CHL1_RS11850	COG1199	ATP-dependent helicase activity
CHL1_RS11865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHL1_RS11965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_RS11970	COG1120	ATPase activity
CHL1_RS11980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHL1_RS11990	COG1051	belongs to the nudix hydrolase family
CHL1_RS11995	COG2033	superoxide reductase activity
CHL1_RS12000	COG3757	hydrolase, family 25
CHL1_RS12005	COG1606	tRNA processing
CHL1_RS12010	COG1132	(ABC) transporter
CHL1_RS12035	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CHL1_RS12050	COG1032	radical SAM domain protein
CHL1_RS12055	COG4536	flavin adenine dinucleotide binding
CHL1_RS12060	COG3835	regulator
CHL1_RS12065	COG1929	Belongs to the glycerate kinase type-1 family
CHL1_RS12075	COG3853	Toxic anion resistance protein (TelA)
CHL1_RS12085	COG1122	ATPase activity
CHL1_RS12095	COG0310	cobalt ion transport
CHL1_RS12100	COG1686	Belongs to the peptidase S11 family
CHL1_RS12110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHL1_RS12135	COG3326	Membrane
CHL1_RS12150	COG5012	cobalamin binding
CHL1_RS12165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_RS12175	COG5012	cobalamin binding
CHL1_RS12190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHL1_RS12210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_RS12215	COG1910	domain protein
CHL1_RS12220	COG0303	'Molybdopterin
CHL1_RS12225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHL1_RS12230	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHL1_RS12245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHL1_RS12250	COG0531	amino acid
CHL1_RS12270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CHL1_RS12295	COG3842	ATPase activity
CHL1_RS12305	COG1177	transmembrane transport
CHL1_RS12350	COG0840	transmembrane signaling receptor activity
CHL1_RS12355	COG0028	Belongs to the TPP enzyme family
CHL1_RS12360	COG0129	dihydroxy-acid dehydratase activity
CHL1_RS12365	COG0473	3-isopropylmalate dehydrogenase activity
CHL1_RS12370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHL1_RS12375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHL1_RS12380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHL1_RS12395	COG0737	Belongs to the 5'-nucleotidase family
CHL1_RS12400	COG4684	Psort location CytoplasmicMembrane, score
CHL1_RS12405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHL1_RS12425	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHL1_RS12440	COG1215	transferase activity, transferring glycosyl groups
CHL1_RS12465	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_RS12470	COG1054	Belongs to the UPF0176 family
CHL1_RS12475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHL1_RS12480	COG0574	Belongs to the PEP-utilizing enzyme family
CHL1_RS12480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHL1_RS12485	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CHL1_RS12490	COG0517	IMP dehydrogenase activity
CHL1_RS12495	COG1596	polysaccharide export
CHL1_RS12495	COG1555	photosystem II stabilization
CHL1_RS12510	COG0765	amino acid transport
CHL1_RS12515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_RS12525	COG0095	Lipoate-protein ligase
CHL1_RS12560	COG5002	protein histidine kinase activity
CHL1_RS12565	COG0745	RESPONSE REGULATOR receiver
CHL1_RS12570	COG0745	RESPONSE REGULATOR receiver
CHL1_RS12575	COG5002	protein histidine kinase activity
CHL1_RS12580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHL1_RS12585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHL1_RS12590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHL1_RS12595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHL1_RS12600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHL1_RS12605	COG0137	argininosuccinate synthase activity
CHL1_RS12610	COG0165	Argininosuccinate lyase
CHL1_RS12635	COG0606	chelatase, subunit chli
CHL1_RS12640	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CHL1_RS12645	COG4869	propanediol catabolic process
CHL1_RS12650	COG0497	DNA recombination
CHL1_RS12655	COG0497	DNA recombination
CHL1_RS12660	COG1438	arginine binding
CHL1_RS12665	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHL1_RS12670	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CHL1_RS12680	COG1722	exodeoxyribonuclease VII activity
CHL1_RS12685	COG1570	exodeoxyribonuclease VII activity
CHL1_RS12690	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHL1_RS12715	COG2890	protein-(glutamine-N5) methyltransferase activity
CHL1_RS12720	COG0254	rRNA binding
CHL1_RS12725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CHL1_RS12745	COG0343	queuine tRNA-ribosyltransferase activity
CHL1_RS12750	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHL1_RS12760	COG0632	four-way junction helicase activity
CHL1_RS12770	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CHL1_RS12780	COG1739	Uncharacterized protein family UPF0029
CHL1_RS12785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHL1_RS12790	COG0301	tRNA thio-modification
CHL1_RS12795	COG1104	cysteine desulfurase activity
CHL1_RS12800	COG0717	Belongs to the dCTP deaminase family
CHL1_RS12805	COG1193	negative regulation of DNA recombination
CHL1_RS12810	COG0826	peptidase U32
CHL1_RS12815	COG1819	glycosyl
CHL1_RS12830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHL1_RS12835	COG0006	proline dipeptidase activity
CHL1_RS12845	COG0037	tRNA processing
CHL1_RS12850	COG0745	RESPONSE REGULATOR receiver
CHL1_RS12855	COG5002	protein histidine kinase activity
CHL1_RS12885	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CHL1_RS12890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHL1_RS12925	COG2188	Transcriptional regulator
CHL1_RS12940	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHL1_RS12945	COG0546	phosphoglycolate phosphatase activity
CHL1_RS12950	COG0613	PHP domain protein
CHL1_RS12960	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_RS12965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHL1_RS12970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHL1_RS12975	COG0095	Lipoate-protein ligase
CHL1_RS12980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_RS12990	COG0022	dehydrogenase e1 component
CHL1_RS12990	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_RS12995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_RS13000	COG0191	fructose-bisphosphate aldolase activity
CHL1_RS13010	COG3958	Transketolase
CHL1_RS13015	COG3959	Transketolase, thiamine diphosphate binding domain
CHL1_RS13110	COG0739	heme binding
CHL1_RS13155	COG0740	serine-type endopeptidase activity
CHL1_RS13290	COG1396	sequence-specific DNA binding
CHL1_RS13295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHL1_RS13300	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CHL1_RS13310	COG0582	viral genome integration into host DNA
CHL1_RS13330	COG0191	fructose-bisphosphate aldolase activity
CHL1_RS13335	COG0564	pseudouridine synthase activity
CHL1_RS13340	COG3331	DNA recombination
CHL1_RS13345	COG1854	S-ribosylhomocysteine lyase activity
CHL1_RS13365	COG2223	nitrite transmembrane transporter activity
CHL1_RS13370	COG2223	nitrite transmembrane transporter activity
CHL1_RS13380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CHL1_RS13405	COG0302	gtp cyclohydrolase
CHL1_RS13410	COG1418	mRNA catabolic process
CHL1_RS13415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHL1_RS13420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CHL1_RS13420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHL1_RS13430	COG0442	prolyl-tRNA aminoacylation
CHL1_RS13435	COG0222	ribosome binding
CHL1_RS13440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHL1_RS13445	COG0081	regulation of translation
CHL1_RS13455	COG0250	Participates in transcription elongation, termination and antitermination
CHL1_RS13470	COG0456	acetyltransferase
CHL1_RS13485	COG1876	peptidase activity
CHL1_RS13520	COG1151	hydroxylamine reductase activity
CHL1_RS13550	COG2871	sodium ion transport
CHL1_RS13565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHL1_RS13575	COG1120	ATPase activity
CHL1_RS13580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_RS13595	COG1120	ATPase activity
CHL1_RS13600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_RS13620	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CHL1_RS13650	COG1342	Belongs to the UPF0251 family
CHL1_RS13705	COG0157	Belongs to the NadC ModD family
CHL1_RS13710	COG2608	mercury ion transmembrane transporter activity
CHL1_RS13715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHL1_RS13720	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CHL1_RS13730	COG3585	molybdate ion transport
CHL1_RS13750	COG0310	cobalt ion transport
CHL1_RS13755	COG1122	ATPase activity
CHL1_RS13790	COG1331	Highly conserved protein containing a thioredoxin domain
CHL1_RS13800	COG1131	(ABC) transporter
CHL1_RS13815	COG1131	(ABC) transporter
CHL1_RS13820	COG1725	Transcriptional regulator
CHL1_RS13830	COG0419	ATPase involved in DNA repair
CHL1_RS13835	COG0419	ATPase involved in DNA repair
CHL1_RS13840	COG0420	3'-5' exonuclease activity
CHL1_RS13865	COG2801	Transposase and inactivated derivatives
CHL1_RS13880	COG3279	Response regulator of the LytR AlgR family
CHL1_RS13895	COG0826	peptidase U32
CHL1_RS13900	COG4122	O-methyltransferase activity
CHL1_RS13905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHL1_RS13910	COG3679	Belongs to the UPF0342 family
CHL1_RS13915	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CHL1_RS13920	COG0735	belongs to the Fur family
CHL1_RS13925	COG1489	DNA binding
CHL1_RS13930	COG3906	Belongs to the UPF0473 family
CHL1_RS13940	COG0667	Aldo Keto reductase
CHL1_RS13945	COG4472	Bacterial protein of unknown function (DUF965)
CHL1_RS13950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHL1_RS13955	COG0628	permease
CHL1_RS13980	COG1959	2 iron, 2 sulfur cluster binding
CHL1_RS13985	COG0539	negative regulation of cytoplasmic translation
CHL1_RS13985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHL1_RS13990	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHL1_RS14000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CHL1_RS14010	COG2081	HI0933 family
CHL1_RS14015	COG1737	Transcriptional regulator
CHL1_RS14020	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CHL1_RS14030	COG1187	pseudouridine synthase activity
CHL1_RS14035	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHL1_RS14040	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CHL1_RS14045	COG1994	Peptidase M50
CHL1_RS14050	COG0494	nUDIX hydrolase
CHL1_RS14055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHL1_RS14060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHL1_RS14070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHL1_RS14075	COG0772	Belongs to the SEDS family
CHL1_RS14080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHL1_RS14085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHL1_RS14090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHL1_RS14095	COG0768	penicillin binding
CHL1_RS14105	COG0275	rRNA processing
CHL1_RS14110	COG2001	Belongs to the MraZ family
CHL1_RS14115	COG3830	Belongs to the UPF0237 family
CHL1_RS14120	COG2848	UPF0210 protein
CHL1_RS14140	COG3835	regulator
CHL1_RS14180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHL1_RS14190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHL1_RS14195	COG1615	UPF0182 protein
CHL1_RS14200	COG1615	UPF0182 protein
CHL1_RS14205	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CHL1_RS14210	COG1136	(ABC) transporter
CHL1_RS14215	COG0577	efflux transmembrane transporter activity
CHL1_RS14215	COG1136	(ABC) transporter
CHL1_RS14240	COG4656	Part of a membrane complex involved in electron transport
CHL1_RS14245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHL1_RS14250	COG3404	Formiminotransferase-cyclodeaminase
CHL1_RS14255	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CHL1_RS14265	COG0252	asparaginase activity
CHL1_RS14285	COG5012	cobalamin binding
CHL1_RS14290	COG0471	metal ion transport
CHL1_RS14295	COG2211	Major facilitator Superfamily
CHL1_RS14310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHL1_RS14315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHL1_RS14320	COG0049	tRNA binding
CHL1_RS14325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHL1_RS14330	COG1358	cellular component organization or biogenesis
CHL1_RS14335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHL1_RS14340	COG0085	RNA polymerase activity
CHL1_RS14350	COG0765	amino acid transport
CHL1_RS14355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_RS14380	COG1461	Dihydroxyacetone kinase
CHL1_RS14385	COG2376	Dihydroxyacetone kinase
CHL1_RS14390	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CHL1_RS14395	COG3829	transcription factor binding
CHL1_RS14395	COG3290	protein histidine kinase activity
CHL1_RS14400	COG0698	ribose 5-phosphate isomerase
CHL1_RS14500	COG0732	type I restriction modification DNA specificity domain
CHL1_RS14505	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CHL1_RS14510	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CHL1_RS14525	COG3620	sequence-specific DNA binding
CHL1_RS14530	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
CHL1_RS14535	COG3875	lactate racemase activity
CHL1_RS14540	COG1620	l-lactate permease
CHL1_RS14545	COG0277	FAD linked oxidase domain protein
CHL1_RS14550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHL1_RS14555	COG2086	electron transfer activity
CHL1_RS14560	COG2188	Transcriptional regulator
CHL1_RS14575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHL1_RS14580	COG2235	arginine
CHL1_RS14585	COG4466	Protein conserved in bacteria
CHL1_RS14590	COG0546	phosphoglycolate phosphatase activity
CHL1_RS14600	COG0077	Prephenate dehydratase
CHL1_RS14600	COG1605	Chorismate mutase
CHL1_RS14605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CHL1_RS14625	COG0488	(ABC) transporter
CHL1_RS14640	COG2188	Transcriptional regulator
CHL1_RS14645	COG5012	cobalamin binding
CHL1_RS14650	COG2116	formate transmembrane transporter activity
CHL1_RS14655	COG2116	formate transmembrane transporter activity
CHL1_RS14660	COG5012	cobalamin binding
CHL1_RS14665	COG2217	Heavy metal translocating P-type atpase
CHL1_RS14670	COG2217	Heavy metal translocating P-type atpase
CHL1_RS14675	COG0640	Transcriptional regulator
CHL1_RS14690	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CHL1_RS14755	COG2188	Transcriptional regulator
CHL1_RS14760	COG5012	cobalamin binding
CHL1_RS14765	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CHL1_RS14770	COG2116	formate transmembrane transporter activity
CHL1_RS14775	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CHL1_RS14785	COG3481	metal-dependent phosphohydrolase, HD sub domain
CHL1_RS14790	COG0436	Aminotransferase
CHL1_RS14830	COG0347	Belongs to the P(II) protein family
CHL1_RS14835	COG0347	Belongs to the P(II) protein family
CHL1_RS14875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_RS14890	COG0347	Belongs to the P(II) protein family
CHL1_RS14900	COG0347	Belongs to the P(II) protein family
CHL1_RS14905	COG0004	ammonium transporteR
CHL1_RS14910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHL1_RS14915	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHL1_RS14920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHL1_RS14935	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHL1_RS14940	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CHL1_RS14960	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CHL1_RS14970	COG1054	Belongs to the UPF0176 family
CHL1_RS14975	COG0745	RESPONSE REGULATOR receiver
CHL1_RS14980	COG5002	protein histidine kinase activity
CHL1_RS15010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_RS15015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_RS15020	COG5012	cobalamin binding
CHL1_RS15025	COG5598	trimethylamine methyltransferase
CHL1_RS15030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_RS15035	COG1962	PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit
CHL1_RS15070	COG0306	phosphate transporter
CHL1_RS15085	COG5012	cobalamin binding
CHL1_RS15095	COG0070	glutamate synthase
CHL1_RS15095	COG0069	glutamate synthase activity
CHL1_RS15095	COG0067	glutamate synthase
CHL1_RS15100	COG0493	'glutamate synthase
CHL1_RS15120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHL1_RS15125	COG3290	protein histidine kinase activity
CHL1_RS15140	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHL1_RS15145	COG5012	cobalamin binding
CHL1_RS15165	COG3706	GGDEF domain
CHL1_RS15170	COG1454	alcohol dehydrogenase
CHL1_RS15195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHL1_RS15200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHL1_RS15220	COG1785	Belongs to the alkaline phosphatase family
CHL1_RS15230	COG4585	Histidine kinase
CHL1_RS15235	COG1131	(ABC) transporter
CHL1_RS15250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHL1_RS15260	COG1902	pentaerythritol trinitrate reductase activity
CHL1_RS15260	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_RS15280	COG4251	negative regulation of phosphorylation
CHL1_RS15280	COG3706	GGDEF domain
CHL1_RS15280	COG2203	Gaf domain
CHL1_RS15280	COG5001	Diguanylate cyclase
CHL1_RS15285	COG0076	glutamate decarboxylase activity
CHL1_RS15435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHL1_RS15450	COG2078	PFAM AMMECR1 domain protein
CHL1_RS15450	COG3885	ferrous iron binding
CHL1_RS15455	COG0148	phosphopyruvate hydratase activity
CHL1_RS15470	COG0210	DNA helicase
CHL1_RS15490	COG4106	trans-aconitate 2-methyltransferase activity
CHL1_RS15495	COG0583	DNA-binding transcription factor activity
CHL1_RS15515	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHL1_RS15515	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHL1_RS15520	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHL1_RS15525	COG2033	superoxide reductase activity
CHL1_RS15545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHL1_RS15670	COG0739	heme binding
CHL1_RS15670	COG0741	lytic transglycosylase activity
CHL1_RS15670	COG1196	nuclear chromosome segregation
CHL1_RS15905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHL1_RS15915	COG0582	viral genome integration into host DNA
CHL1_RS15925	COG0084	hydrolase, TatD family'
CHL1_RS15930	COG0617	tRNA 3'-terminal CCA addition
CHL1_RS15945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHL1_RS15965	COG4129	membrane
CHL1_RS15975	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CHL1_RS15980	COG2873	o-acetylhomoserine
CHL1_RS15985	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CHL1_RS15995	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CHL1_RS16000	COG0390	transport system, permease component
CHL1_RS16005	COG1122	ATPase activity
CHL1_RS16010	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CHL1_RS16010	COG0778	Nitroreductase
CHL1_RS16035	COG4999	Histidine kinase
CHL1_RS16035	COG3437	response regulator, receiver
CHL1_RS16035	COG2205	protein histidine kinase activity
CHL1_RS16035	COG3850	Histidine kinase
CHL1_RS16050	COG3706	GGDEF domain
CHL1_RS16075	COG1126	abc transporter atp-binding protein
CHL1_RS16080	COG0765	amino acid transport
CHL1_RS16085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_RS16100	COG2200	EAL domain
CHL1_RS16110	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_RS16110	COG2199	diguanylate cyclase activity
CHL1_RS16140	COG2226	methyltransferase
CHL1_RS16155	COG0010	Belongs to the arginase family
CHL1_RS16160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CHL1_RS16165	COG1982	Orn Lys Arg decarboxylase major
CHL1_RS16180	COG4999	Histidine kinase
CHL1_RS16180	COG3850	Histidine kinase
CHL1_RS16180	COG3437	response regulator, receiver
CHL1_RS16180	COG2205	protein histidine kinase activity
CHL1_RS16185	COG3437	response regulator, receiver
CHL1_RS16195	COG0569	domain protein
CHL1_RS16200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHL1_RS16210	COG3973	AAA domain
CHL1_RS16220	COG5012	cobalamin binding
CHL1_RS16245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHL1_RS16250	COG1121	(ABC) transporter
CHL1_RS16270	COG0352	thiamine-phosphate diphosphorylase activity
CHL1_RS16270	COG0351	phosphomethylpyrimidine kinase
CHL1_RS16275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHL1_RS16285	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CHL1_RS16290	COG2878	Part of a membrane complex involved in electron transport
CHL1_RS16290	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL1_RS16295	COG4657	Part of a membrane complex involved in electron transport
CHL1_RS16300	COG4660	Part of a membrane complex involved in electron transport
CHL1_RS16305	COG4659	FMN binding
CHL1_RS16310	COG4658	electron transport chain
CHL1_RS16315	COG4656	Part of a membrane complex involved in electron transport
CHL1_RS16325	COG0785	Cytochrome C biogenesis protein
CHL1_RS16330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHL1_RS16340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHL1_RS16345	COG3118	belongs to the thioredoxin family
CHL1_RS16355	COG1132	(ABC) transporter
CHL1_RS16360	COG1132	(ABC) transporter
CHL1_RS16365	COG1132	(ABC) transporter
CHL1_RS16370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHL1_RS16375	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CHL1_RS16380	COG0733	neurotransmitter:sodium symporter activity
CHL1_RS16405	COG2801	Transposase and inactivated derivatives
CHL1_RS16415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHL1_RS16430	COG1086	Polysaccharide biosynthesis protein
CHL1_RS16470	COG0438	transferase activity, transferring glycosyl groups
CHL1_RS16475	COG1216	Glycosyl transferase, family 2
CHL1_RS16485	COG0438	transferase activity, transferring glycosyl groups
CHL1_RS16490	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CHL1_RS16515	COG3206	protein involved in exopolysaccharide biosynthesis
CHL1_RS16515	COG0489	protein tyrosine kinase activity
CHL1_RS16530	COG1328	CTP reductase activity
CHL1_RS16530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHL1_RS16550	COG0477	Major facilitator Superfamily
CHL1_RS16560	COG3437	response regulator, receiver
CHL1_RS16565	COG1045	serine acetyltransferase
CHL1_RS16580	COG1027	Aspartate ammonia-lyase
CHL1_RS16590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_RS16595	COG1120	ATPase activity
CHL1_RS16605	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHL1_RS16640	COG1876	peptidase activity
CHL1_RS16645	COG0697	spore germination
CHL1_RS16650	COG1917	Cupin 2, conserved barrel domain protein
CHL1_RS16650	COG2207	Transcriptional regulator
CHL1_RS16660	COG3835	regulator
CHL1_RS16665	COG1454	alcohol dehydrogenase
CHL1_RS16675	COG2199	diguanylate cyclase activity
CHL1_RS16695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHL1_RS16705	COG0387	Pfam Sodium calcium exchanger
CHL1_RS16710	COG3706	GGDEF domain
CHL1_RS16730	COG2261	transglycosylase associated protein
CHL1_RS16735	COG2357	RelA SpoT domain protein
CHL1_RS16740	COG1592	Rubrerythrin
CHL1_RS16755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_RS16760	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHL1_RS16760	COG3608	succinylglutamate desuccinylase aspartoacylase
CHL1_RS16790	COG3875	lactate racemase activity
CHL1_RS16795	COG0281	malic enzyme
CHL1_RS16800	COG0126	phosphoglycerate kinase activity
CHL1_RS16815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_RS16825	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_RS16825	COG0022	dehydrogenase e1 component
CHL1_RS16830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_RS16835	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHL1_RS16870	COG0840	transmembrane signaling receptor activity
CHL1_RS16875	COG2274	protein secretion by the type I secretion system
CHL1_RS16930	COG1247	-acetyltransferase
CHL1_RS16940	COG2378	regulation of single-species biofilm formation
CHL1_RS16945	COG0584	glycerophosphoryl diester phosphodiesterase
CHL1_RS16950	COG0584	glycerophosphoryl diester phosphodiesterase
CHL1_RS16960	COG1611	Belongs to the LOG family
CHL1_RS16970	COG1733	regulation of RNA biosynthetic process
CHL1_RS16985	COG3620	sequence-specific DNA binding
CHL1_RS16995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHL1_RS16995	COG0574	Belongs to the PEP-utilizing enzyme family
CHL1_RS17010	COG0765	amino acid transport
CHL1_RS17035	COG2770	Histidine kinase
CHL1_RS17035	COG2208	phosphoserine phosphatase activity
CHL1_RS17040	COG0534	Mate efflux family protein
CHL1_RS17045	COG0745	RESPONSE REGULATOR receiver
CHL1_RS17080	COG0534	Mate efflux family protein
CHL1_RS17090	COG3384	dioxygenase
CHL1_RS17100	COG5012	cobalamin binding
CHL1_RS17105	COG2824	Alkylphosphonate utilization operon protein PhnA
CHL1_RS17110	COG0745	RESPONSE REGULATOR receiver
CHL1_RS17110	COG2972	Histidine kinase
CHL1_RS17115	COG3279	Response regulator of the LytR AlgR family
CHL1_RS17120	COG3706	GGDEF domain
CHL1_RS17145	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_RS17165	COG0667	Aldo Keto reductase
CHL1_RS17175	COG0110	maltose O-acetyltransferase activity
CHL1_RS17185	COG0656	L-ascorbic acid biosynthetic process
CHL1_RS17190	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CHL1_RS17195	COG1691	(AIR) carboxylase
CHL1_RS17210	COG0789	Transcriptional regulator
CHL1_RS17240	COG0667	Aldo Keto reductase
CHL1_RS17250	COG3706	GGDEF domain
CHL1_RS17280	COG3850	Histidine kinase
CHL1_RS17280	COG5002	protein histidine kinase activity
CHL1_RS17285	COG0745	RESPONSE REGULATOR receiver
CHL1_RS17305	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_RS17330	COG2814	Major facilitator Superfamily
CHL1_RS17335	COG1309	transcriptional regulator
CHL1_RS17345	COG2814	Major facilitator Superfamily
CHL1_RS17355	COG2200	EAL domain
CHL1_RS17355	COG2199	diguanylate cyclase activity
CHL1_RS17360	COG2199	diguanylate cyclase activity
CHL1_RS17375	COG2199	diguanylate cyclase activity
CHL1_RS17375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_RS17400	COG2801	Transposase and inactivated derivatives
CHL1_RS17415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHL1_RS17425	COG3588	fructose-bisphosphate aldolase
CHL1_RS17435	COG3973	AAA domain
CHL1_RS17440	COG2801	Transposase and inactivated derivatives
CHL1_RS17460	COG3620	sequence-specific DNA binding
CHL1_RS17500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHL1_RS17505	COG1357	PFAM Pentapeptide repeats (8 copies)
CHL1_RS17560	COG1595	DNA-templated transcription, initiation
CHL1_RS17580	COG3706	GGDEF domain
CHL1_RS17590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHL1_RS17600	COG1131	(ABC) transporter
CHL1_RS17625	COG4716	Myosin-crossreactive antigen
CHL1_RS17630	COG1309	transcriptional regulator
CHL1_RS17640	COG0477	Major facilitator Superfamily
CHL1_RS17655	COG2801	Transposase and inactivated derivatives
CHL1_RS17670	COG1136	(ABC) transporter
CHL1_RS17670	COG0577	efflux transmembrane transporter activity
CHL1_RS17685	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CHL1_RS17700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHL1_RS17705	COG0697	spore germination
CHL1_RS17715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CHL1_RS17735	COG4443	Transcriptional Coactivator p15 (PC4)
CHL1_RS17740	COG1475	DNA binding
CHL1_RS17845	COG0384	phenazine biosynthesis protein PhzF
CHL1_RS17895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHL1_RS17900	COG2217	Heavy metal translocating P-type atpase
CHL1_RS17915	COG2770	Histidine kinase
CHL1_RS17915	COG3437	response regulator, receiver
CHL1_RS17945	COG1846	Transcriptional regulator
CHL1_RS17950	COG1024	Enoyl-CoA hydratase
CHL1_RS17955	COG0583	DNA-binding transcription factor activity
CHL1_RS18045	COG2207	Transcriptional regulator
CHL1_RS18045	COG3708	Transcriptional regulator
CHL1_RS18070	COG0488	(ABC) transporter
CHL1_RS18085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHL1_RS18095	COG1511	domain protein
CHL1_RS18100	COG3118	belongs to the thioredoxin family
CHL1_RS18130	COG1774	PSP1 C-terminal conserved region
CHL1_RS18145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHL1_RS18155	COG1982	Orn Lys Arg decarboxylase major
CHL1_RS18160	COG3118	belongs to the thioredoxin family
CHL1_RS18170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHL1_RS18175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_RS18180	COG0305	Participates in initiation and elongation during chromosome replication
CHL1_RS18190	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CHL1_RS18195	COG4241	membrane
CHL1_RS18205	COG0629	single-stranded DNA binding
CHL1_RS18210	COG0360	Binds together with S18 to 16S ribosomal RNA
CHL1_RS18225	COG0668	transmembrane transport
CHL1_RS18240	COG1475	DNA binding
CHL1_RS18245	COG1192	Involved in chromosome partitioning
CHL1_RS18250	COG0357	Ribosomal RNA small subunit methyltransferase G
CHL1_RS18260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHL1_RS18265	COG1847	R3H domain protein
CHL1_RS18270	COG0706	membrane insertase activity
CHL1_RS18275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CHL1_RS18280	COG0594	ribonuclease P activity