locus-tag	class	description
BN854_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BN854_RS00015	COG0592	DNA-directed DNA polymerase activity
BN854_RS00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BN854_RS00035	COG0187	DNA topoisomerase II activity
BN854_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BN854_RS00115	COG0534	Mate efflux family protein
BN854_RS00215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BN854_RS00235	COG1136	(ABC) transporter
BN854_RS00235	COG0577	efflux transmembrane transporter activity
BN854_RS00245	COG1733	regulation of RNA biosynthetic process
BN854_RS00250	COG1373	ATPase (AAA superfamily
BN854_RS00260	COG0431	NADPH-dependent FMN reductase
BN854_RS00265	COG0656	L-ascorbic acid biosynthetic process
BN854_RS00285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BN854_RS00290	COG2011	ABC-type metal ion transport system permease component
BN854_RS00295	COG1464	Belongs to the NlpA lipoprotein family
BN854_RS00300	COG3340	Belongs to the peptidase S51 family
BN854_RS00305	COG1136	(ABC) transporter
BN854_RS00310	COG1136	(ABC) transporter
BN854_RS00310	COG0577	efflux transmembrane transporter activity
BN854_RS00325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BN854_RS00340	COG0537	adenosine 5'-monophosphoramidase activity
BN854_RS00345	COG4869	propanediol catabolic process
BN854_RS00485	COG1078	dGTPase activity
BN854_RS00490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BN854_RS00495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BN854_RS00500	COG2088	sporulation resulting in formation of a cellular spore
BN854_RS00505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BN854_RS00510	COG0193	aminoacyl-tRNA hydrolase activity
BN854_RS00515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BN854_RS00520	COG1448	Aminotransferase
BN854_RS00540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BN854_RS00545	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BN854_RS00565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BN854_RS00570	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BN854_RS00580	COG1307	EDD domain protein, DegV family
BN854_RS00595	COG1098	S1 RNA binding domain
BN854_RS00600	COG0166	Belongs to the GPI family
BN854_RS00605	COG0802	atpase or kinase
BN854_RS00615	COG0456	acetyltransferase
BN854_RS00620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BN854_RS00635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BN854_RS00670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BN854_RS00675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BN854_RS00685	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BN854_RS00690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BN854_RS00695	COG0492	ferredoxin-NADP+ reductase activity
BN854_RS00705	COG0736	holo-[acyl-carrier-protein] synthase activity
BN854_RS00715	COG2183	response to ionizing radiation
BN854_RS00760	COG1982	Orn Lys Arg decarboxylase major
BN854_RS00765	COG0010	Belongs to the arginase family
BN854_RS00775	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BN854_RS00815	COG1609	Transcriptional regulator
BN854_RS00825	COG0095	Lipoate-protein ligase
BN854_RS00865	COG0581	inorganic phosphate transmembrane transporter activity
BN854_RS00875	COG0704	Plays a role in the regulation of phosphate uptake
BN854_RS00880	COG0745	RESPONSE REGULATOR receiver
BN854_RS00885	COG5002	protein histidine kinase activity
BN854_RS00890	COG1328	CTP reductase activity
BN854_RS00890	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BN854_RS00895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BN854_RS00900	COG1780	Probably involved in ribonucleotide reductase function
BN854_RS00905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BN854_RS00910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BN854_RS00930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BN854_RS00945	COG2801	Transposase and inactivated derivatives
BN854_RS01005	COG4974	Belongs to the 'phage' integrase family
BN854_RS01090	COG1454	alcohol dehydrogenase
BN854_RS01100	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BN854_RS01140	COG0601	transmembrane transport
BN854_RS01150	COG0444	Belongs to the ABC transporter superfamily
BN854_RS01155	COG4608	Belongs to the ABC transporter superfamily
BN854_RS01165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BN854_RS01170	COG0396	ATPase activity
BN854_RS01175	COG0719	Fe-S assembly protein
BN854_RS01180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BN854_RS01185	COG0822	iron-sulfur transferase activity
BN854_RS01200	COG2508	Transcriptional regulator
BN854_RS01205	COG3842	ATPase activity
BN854_RS01215	COG0126	phosphoglycerate kinase activity
BN854_RS01230	COG0149	triose-phosphate isomerase activity
BN854_RS01240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN854_RS01245	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BN854_RS01250	COG1956	GAF domain-containing protein
BN854_RS01255	COG0301	tRNA thio-modification
BN854_RS01260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BN854_RS01270	COG0242	peptide deformylase activity
BN854_RS01295	COG0228	four-way junction DNA binding
BN854_RS01300	COG1837	Belongs to the UPF0109 family
BN854_RS01305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BN854_RS01310	COG0336	Belongs to the RNA methyltransferase TrmD family
BN854_RS01315	COG0335	large ribosomal subunit rRNA binding
BN854_RS01325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BN854_RS01345	COG0686	Belongs to the AlaDH PNT family
BN854_RS01355	COG0180	Tryptophanyl-tRNA synthetase
BN854_RS01360	COG1164	Oligoendopeptidase f
BN854_RS01365	COG1393	Belongs to the ArsC family
BN854_RS01385	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BN854_RS01395	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BN854_RS01400	COG4974	Belongs to the 'phage' integrase family
BN854_RS01405	COG0756	dUTP diphosphatase activity
BN854_RS01410	COG0052	Belongs to the universal ribosomal protein uS2 family
BN854_RS01415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BN854_RS01420	COG0528	UMP kinase activity
BN854_RS01425	COG0233	cytoplasmic translational termination
BN854_RS01430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BN854_RS01435	COG4589	Belongs to the CDS family
BN854_RS01470	COG0572	uridine kinase
BN854_RS01475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BN854_RS01525	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BN854_RS01570	COG1054	Belongs to the UPF0176 family
BN854_RS01585	COG2610	gluconate transmembrane transporter activity
BN854_RS01590	COG1929	Belongs to the glycerate kinase type-1 family
BN854_RS01610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BN854_RS01630	COG0732	type I restriction modification DNA specificity domain
BN854_RS01635	COG0582	viral genome integration into host DNA
BN854_RS01690	COG1694	Mazg nucleotide pyrophosphohydrolase
BN854_RS01695	COG1611	Belongs to the LOG family
BN854_RS01715	COG0501	Belongs to the peptidase M48B family
BN854_RS01725	COG0488	(ABC) transporter
BN854_RS01735	COG1827	regulation of RNA biosynthetic process
BN854_RS01780	COG0194	GDP metabolic process
BN854_RS01785	COG0450	alkyl hydroperoxide reductase
BN854_RS01825	COG1131	(ABC) transporter
BN854_RS01835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BN854_RS01845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BN854_RS01850	COG1959	2 iron, 2 sulfur cluster binding
BN854_RS01860	COG1132	(ABC) transporter
BN854_RS01890	COG1346	cytolysis
BN854_RS01900	COG1132	(ABC) transporter
BN854_RS01905	COG1902	pentaerythritol trinitrate reductase activity
BN854_RS01925	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BN854_RS01935	COG1609	Transcriptional regulator
BN854_RS01945	COG1312	Catalyzes the dehydration of D-mannonate
BN854_RS01950	COG0246	Mannitol dehydrogenase
BN854_RS01995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BN854_RS02000	COG1126	abc transporter atp-binding protein
BN854_RS02005	COG0765	amino acid transport
BN854_RS02015	COG0038	chloride channel
BN854_RS02020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BN854_RS02030	COG0495	leucyl-tRNA aminoacylation
BN854_RS02035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BN854_RS02040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BN854_RS02045	COG1242	4 iron, 4 sulfur cluster binding
BN854_RS02055	COG2176	DNA-directed DNA polymerase activity
BN854_RS02065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BN854_RS02070	COG0072	phenylalanine-tRNA ligase activity
BN854_RS02070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BN854_RS02075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BN854_RS02080	COG1162	GTPase activity
BN854_RS02085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BN854_RS02095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BN854_RS02100	COG1461	Dihydroxyacetone kinase
BN854_RS02115	COG1132	(ABC) transporter
BN854_RS02120	COG3557	Belongs to the UPF0374 family
BN854_RS02140	COG0519	Catalyzes the synthesis of GMP from XMP
BN854_RS02155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN854_RS02160	COG0765	amino acid transport
BN854_RS02165	COG1126	abc transporter atp-binding protein
BN854_RS02175	COG2996	Protein conserved in bacteria
BN854_RS02180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BN854_RS02200	COG1269	ATP hydrolysis coupled proton transport
BN854_RS02230	COG1394	ATPase activity, coupled to movement of substances
BN854_RS02235	COG1823	symporter activity
BN854_RS02275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BN854_RS02285	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BN854_RS02290	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BN854_RS02305	COG0195	Participates in both transcription termination and antitermination
BN854_RS02310	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BN854_RS02320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BN854_RS02325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BN854_RS02330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BN854_RS02335	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BN854_RS02340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BN854_RS02350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BN854_RS02360	COG2816	NAD+ diphosphatase activity
BN854_RS02365	COG0653	protein targeting
BN854_RS02370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BN854_RS02375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BN854_RS02380	COG0793	Belongs to the peptidase S41A family
BN854_RS02380	COG3409	Peptidoglycan-binding domain 1 protein
BN854_RS02390	COG0561	phosphatase activity
BN854_RS02400	COG1674	ftsk spoiiie
BN854_RS02405	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BN854_RS02410	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BN854_RS02420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BN854_RS02425	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BN854_RS02430	COG0552	protein localization to endoplasmic reticulum
BN854_RS02435	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BN854_RS02440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BN854_RS02445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BN854_RS02445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BN854_RS02450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BN854_RS02455	COG0237	dephospho-CoA kinase activity
BN854_RS02465	COG1484	DNA-dependent DNA replication
BN854_RS02475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BN854_RS02480	COG4152	abc transporter atp-binding protein
BN854_RS02490	COG0489	protein tyrosine kinase activity
BN854_RS02510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BN854_RS02520	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BN854_RS02525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BN854_RS02540	COG0632	four-way junction helicase activity
BN854_RS02545	COG2255	four-way junction helicase activity
BN854_RS02555	COG1968	undecaprenyl-diphosphatase activity
BN854_RS02565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN854_RS02575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BN854_RS02580	COG1363	Peptidase, m42
BN854_RS02585	COG0656	L-ascorbic acid biosynthetic process
BN854_RS02595	COG0246	Mannitol dehydrogenase
BN854_RS02600	COG2721	sulfolactate sulfo-lyase activity
BN854_RS02605	COG1904	glucuronate isomerase
BN854_RS02615	COG4209	transmembrane transport
BN854_RS02620	COG0395	ABC-type sugar transport system, permease component
BN854_RS02635	COG3842	ATPase activity
BN854_RS02665	COG0363	glucosamine-6-phosphate deaminase activity
BN854_RS02670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BN854_RS02675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BN854_RS02685	COG0174	glutamine synthetase
BN854_RS02705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BN854_RS02715	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN854_RS02720	COG5001	Diguanylate cyclase
BN854_RS02720	COG3300	MHYT domain
BN854_RS02775	COG5001	Diguanylate cyclase
BN854_RS02780	COG1464	Belongs to the NlpA lipoprotein family
BN854_RS02785	COG2011	ABC-type metal ion transport system permease component
BN854_RS02805	COG2195	Cleaves the N-terminal amino acid of tripeptides
BN854_RS02810	COG1012	belongs to the aldehyde dehydrogenase family
BN854_RS02815	COG1132	(ABC) transporter
BN854_RS02820	COG1132	(ABC) transporter
BN854_RS02825	COG0312	modulator of DNA gyrase
BN854_RS02830	COG0312	modulator of DNA gyrase
BN854_RS02855	COG0803	Belongs to the bacterial solute-binding protein 9 family
BN854_RS02860	COG1121	(ABC) transporter
BN854_RS02865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BN854_RS02870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BN854_RS02875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BN854_RS02875	COG1321	iron dependent repressor
BN854_RS02880	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BN854_RS02890	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BN854_RS02895	COG1760	l-serine dehydratase
BN854_RS02900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BN854_RS02905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BN854_RS02910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BN854_RS02920	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BN854_RS02925	COG4605	iron ion homeostasis
BN854_RS02930	COG4604	ABC transporter, ATP-binding protein
BN854_RS02955	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BN854_RS02960	COG1702	phosphate starvation-inducible protein PhoH
BN854_RS02965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BN854_RS02970	COG0295	cytidine deaminase activity
BN854_RS02990	COG0358	DNA primase activity
BN854_RS02995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BN854_RS03010	COG1132	(ABC) transporter
BN854_RS03030	COG0523	cobalamin synthesis protein
BN854_RS03040	COG2824	Alkylphosphonate utilization operon protein PhnA
BN854_RS03045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BN854_RS03050	COG1121	(ABC) transporter
BN854_RS03075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN854_RS03075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN854_RS03075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN854_RS03080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN854_RS03080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN854_RS03080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN854_RS03085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN854_RS03085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN854_RS03085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN854_RS03115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BN854_RS03155	COG0584	glycerophosphoryl diester phosphodiesterase
BN854_RS03160	COG1573	uracil-dna glycosylase
BN854_RS03165	COG0800	Aldolase
BN854_RS03175	COG2731	YhcH YjgK YiaL family protein
BN854_RS03200	COG1028	Short-chain dehydrogenase reductase Sdr
BN854_RS03205	COG1420	regulation of RNA biosynthetic process
BN854_RS03210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BN854_RS03215	COG0443	Heat shock 70 kDa protein
BN854_RS03235	COG4209	transmembrane transport
BN854_RS03240	COG0395	ABC-type sugar transport system, permease component
BN854_RS03265	COG3842	ATPase activity
BN854_RS03275	COG3507	Belongs to the glycosyl hydrolase 43 family
BN854_RS03280	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BN854_RS03290	COG1070	Carbohydrate kinase
BN854_RS03305	COG1012	belongs to the aldehyde dehydrogenase family
BN854_RS03305	COG1454	alcohol dehydrogenase
BN854_RS03310	COG0095	Lipoate-protein ligase
BN854_RS03315	COG0509	glycine decarboxylation via glycine cleavage system
BN854_RS03325	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BN854_RS03335	COG0577	efflux transmembrane transporter activity
BN854_RS03345	COG2239	Acts as a magnesium transporter
BN854_RS03350	COG2239	Acts as a magnesium transporter
BN854_RS03440	COG0531	amino acid
BN854_RS03460	COG4974	Belongs to the 'phage' integrase family
BN854_RS03470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BN854_RS03480	COG0322	excinuclease ABC activity
BN854_RS03490	COG1132	(ABC) transporter
BN854_RS03495	COG1132	(ABC) transporter
BN854_RS03500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BN854_RS03505	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BN854_RS03515	COG4122	O-methyltransferase activity
BN854_RS03525	COG0826	peptidase U32
BN854_RS03535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BN854_RS03540	COG1011	Hydrolase
BN854_RS03560	COG0799	negative regulation of ribosome biogenesis
BN854_RS03575	COG0658	competence protein
BN854_RS03575	COG2333	competence protein COMEC
BN854_RS03585	COG1466	dna polymerase III delta subunit
BN854_RS03595	COG0268	Binds directly to 16S ribosomal RNA
BN854_RS03605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BN854_RS03615	COG4372	Transposase
BN854_RS03615	COG1418	mRNA catabolic process
BN854_RS03620	COG1418	mRNA catabolic process
BN854_RS03625	COG1692	metallophosphoesterase
BN854_RS03640	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BN854_RS03645	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BN854_RS03650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BN854_RS03655	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BN854_RS03660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BN854_RS03665	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BN854_RS03670	COG1187	pseudouridine synthase activity
BN854_RS03675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BN854_RS03680	COG0539	negative regulation of cytoplasmic translation
BN854_RS03685	COG1160	GTP binding
BN854_RS03690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BN854_RS03695	COG0776	regulation of translation
BN854_RS03710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BN854_RS03830	COG4974	Belongs to the 'phage' integrase family
BN854_RS03860	COG0488	(ABC) transporter
BN854_RS03865	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BN854_RS03870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BN854_RS03880	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BN854_RS03885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BN854_RS03890	COG0006	proline dipeptidase activity
BN854_RS03910	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BN854_RS03915	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BN854_RS03920	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BN854_RS03930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BN854_RS03940	COG1363	Peptidase, m42
BN854_RS03985	COG3331	DNA recombination
BN854_RS03995	COG0488	(ABC) transporter
BN854_RS04010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BN854_RS04015	COG0346	lactoylglutathione lyase activity
BN854_RS04020	COG0346	lactoylglutathione lyase activity
BN854_RS04025	COG1846	Transcriptional regulator
BN854_RS04040	COG2755	lipolytic protein G-D-S-L family
BN854_RS04045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BN854_RS04050	COG1132	(ABC) transporter
BN854_RS04055	COG1132	(ABC) transporter
BN854_RS04075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BN854_RS04080	COG0459	protein refolding
BN854_RS04100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BN854_RS04120	COG0519	Catalyzes the synthesis of GMP from XMP
BN854_RS04135	COG0492	ferredoxin-NADP+ reductase activity
BN854_RS04160	COG1028	Short-chain dehydrogenase reductase Sdr
BN854_RS04180	COG3279	Response regulator of the LytR AlgR family
BN854_RS04195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BN854_RS04230	COG1305	Transglutaminase-like
BN854_RS04265	COG1253	flavin adenine dinucleotide binding
BN854_RS04310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BN854_RS04320	COG1744	ABC transporter substrate-binding protein PnrA-like
BN854_RS04325	COG3845	ABC transporter
BN854_RS04330	COG4603	Belongs to the binding-protein-dependent transport system permease family
BN854_RS04335	COG1079	Belongs to the binding-protein-dependent transport system permease family
BN854_RS04350	COG0561	phosphatase activity
BN854_RS04360	COG0546	phosphoglycolate phosphatase activity
BN854_RS04365	COG3022	response to hydroperoxide
BN854_RS04370	COG0778	Nitroreductase
BN854_RS04375	COG1194	a g-specific adenine glycosylase
BN854_RS04385	COG0343	queuine tRNA-ribosyltransferase activity
BN854_RS04390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BN854_RS04395	COG0012	GTP binding
BN854_RS04400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BN854_RS04410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BN854_RS04430	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BN854_RS04435	COG0813	purine-nucleoside phosphorylase activity
BN854_RS04450	COG0629	single-stranded DNA binding
BN854_RS04455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BN854_RS04460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BN854_RS04465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BN854_RS04475	COG0588	phosphoglycerate mutase activity
BN854_RS04490	COG0640	Transcriptional regulator
BN854_RS04495	COG2217	Heavy metal translocating P-type atpase
BN854_RS04505	COG0742	ribosomal rna small subunit methyltransferase
BN854_RS04510	COG3763	UPF0154 protein
BN854_RS04520	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BN854_RS04525	COG4974	Belongs to the 'phage' integrase family
BN854_RS04530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BN854_RS04545	COG0481	GTPase activity
BN854_RS04560	COG2267	carboxylic ester hydrolase activity
BN854_RS04565	COG0285	dihydrofolate synthase activity
BN854_RS04575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BN854_RS04600	COG2502	aspartate--ammonia ligase
BN854_RS04610	COG0039	L-malate dehydrogenase activity
BN854_RS04615	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BN854_RS04625	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BN854_RS04630	COG0544	peptidyl-prolyl cis-trans isomerase activity
BN854_RS04645	COG1136	(ABC) transporter
BN854_RS04660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BN854_RS04665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BN854_RS04670	COG2746	aminoglycoside 3-N-acetyltransferase activity
BN854_RS04675	COG1185	polyribonucleotide nucleotidyltransferase activity
BN854_RS04685	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BN854_RS04690	COG3870	Protein conserved in bacteria
BN854_RS04695	COG0196	riboflavin kinase activity
BN854_RS04700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BN854_RS04715	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BN854_RS04720	COG1472	Belongs to the glycosyl hydrolase 3 family
BN854_RS04725	COG3842	ATPase activity
BN854_RS04760	COG4555	ABC transporter
BN854_RS04775	COG0516	GMP reductase activity
BN854_RS04785	COG1304	FMN binding
BN854_RS04800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BN854_RS04805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BN854_RS04815	COG0386	Belongs to the glutathione peroxidase family
BN854_RS04825	COG3459	Glycosyltransferase 36 associated
BN854_RS04830	COG0395	ABC-type sugar transport system, permease component
BN854_RS04835	COG1175	transmembrane transport
BN854_RS04860	COG0564	pseudouridine synthase activity
BN854_RS04865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BN854_RS04885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BN854_RS04890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BN854_RS04895	COG0124	histidyl-tRNA synthetase
BN854_RS04910	COG1490	D-aminoacyl-tRNA deacylase activity
BN854_RS04915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BN854_RS04920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BN854_RS04925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BN854_RS04940	COG0673	inositol 2-dehydrogenase activity
BN854_RS04950	COG2017	converts alpha-aldose to the beta-anomer
BN854_RS04955	COG4948	Mandelate Racemase Muconate Lactonizing
BN854_RS04960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BN854_RS04965	COG0482	sulfurtransferase activity
BN854_RS04975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BN854_RS04985	COG1803	Methylglyoxal synthase
BN854_RS04990	COG0275	rRNA processing
BN854_RS05000	COG0194	GDP metabolic process
BN854_RS05005	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BN854_RS05010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BN854_RS05035	COG1131	(ABC) transporter
BN854_RS05040	COG1725	Transcriptional regulator
BN854_RS05055	COG2153	protein acetylation
BN854_RS05060	COG0671	phosphoesterase, PA-phosphatase related
BN854_RS05070	COG0557	exoribonuclease II activity
BN854_RS05075	COG0148	phosphopyruvate hydratase activity
BN854_RS05090	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BN854_RS05110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BN854_RS05115	COG0187	DNA topoisomerase II activity
BN854_RS05130	COG2249	NAD(P)H dehydrogenase (quinone) activity
BN854_RS05135	COG0668	transmembrane transport
BN854_RS05150	COG2217	Heavy metal translocating P-type atpase
BN854_RS05155	COG0640	Transcriptional regulator
BN854_RS05160	COG1132	(ABC) transporter
BN854_RS05165	COG1132	(ABC) transporter
BN854_RS05170	COG1846	Transcriptional regulator
BN854_RS05195	COG2081	HI0933 family
BN854_RS05205	COG1192	Involved in chromosome partitioning
BN854_RS05230	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN854_RS05240	COG0438	transferase activity, transferring glycosyl groups
BN854_RS05255	COG0513	Belongs to the DEAD box helicase family
BN854_RS05270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN854_RS05275	COG0745	RESPONSE REGULATOR receiver
BN854_RS05280	COG2205	protein histidine kinase activity
BN854_RS05295	COG0513	Belongs to the DEAD box helicase family
BN854_RS05300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BN854_RS05310	COG3590	peptidase
BN854_RS05325	COG0170	dolichyl monophosphate biosynthetic process
BN854_RS05330	COG1562	ergosterol biosynthetic process
BN854_RS05335	COG1233	COG1233 Phytoene dehydrogenase and related
BN854_RS05355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BN854_RS05360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BN854_RS05365	COG1272	protein, Hemolysin III
BN854_RS05385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BN854_RS05400	COG0018	arginyl-trna synthetase
BN854_RS05410	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BN854_RS05420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BN854_RS05425	COG0497	DNA recombination
BN854_RS05430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BN854_RS05435	COG1722	exodeoxyribonuclease VII activity
BN854_RS05440	COG1570	exodeoxyribonuclease VII activity
BN854_RS05445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BN854_RS05460	COG1177	transmembrane transport
BN854_RS05465	COG1176	ABC-type spermidine putrescine transport system, permease component I
BN854_RS05470	COG3839	Belongs to the ABC transporter superfamily
BN854_RS05485	COG1177	transmembrane transport
BN854_RS05490	COG1176	ABC-type spermidine putrescine transport system, permease component I
BN854_RS05495	COG3842	ATPase activity
BN854_RS05500	COG1307	EDD domain protein, DegV family
BN854_RS05510	COG0492	ferredoxin-NADP+ reductase activity
BN854_RS05515	COG1268	BioY protein
BN854_RS05520	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BN854_RS05520	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BN854_RS05530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BN854_RS05535	COG1028	Short-chain dehydrogenase reductase Sdr
BN854_RS05540	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BN854_RS05550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BN854_RS05560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BN854_RS05565	COG0439	Biotin carboxylase
BN854_RS05575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BN854_RS05590	COG1584	GPR1 FUN34 yaaH family protein
BN854_RS05600	COG0745	RESPONSE REGULATOR receiver
BN854_RS05605	COG5002	protein histidine kinase activity
BN854_RS05610	COG0438	transferase activity, transferring glycosyl groups
BN854_RS05630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BN854_RS05635	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BN854_RS05650	COG1216	Glycosyl transferase, family 2
BN854_RS05650	COG1442	glycosyl transferase family 8
BN854_RS05660	COG1442	glycosyl transferase family 8
BN854_RS05660	COG1216	Glycosyl transferase, family 2
BN854_RS05665	COG0438	transferase activity, transferring glycosyl groups
BN854_RS05670	COG0438	transferase activity, transferring glycosyl groups
BN854_RS05680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BN854_RS05780	COG1164	Oligoendopeptidase f
BN854_RS05785	COG0556	nucleotide-excision repair
BN854_RS05825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BN854_RS05840	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BN854_RS05860	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BN854_RS05945	COG1132	(ABC) transporter
BN854_RS05950	COG1132	(ABC) transporter
BN854_RS05965	COG0205	6-phosphofructokinase activity
BN854_RS05980	COG0205	6-phosphofructokinase activity
BN854_RS05995	COG3300	MHYT domain
BN854_RS05995	COG5001	Diguanylate cyclase
BN854_RS06000	COG1132	(ABC) transporter
BN854_RS06005	COG0587	DNA-directed DNA polymerase activity
BN854_RS06020	COG1132	(ABC) transporter
BN854_RS06025	COG1132	(ABC) transporter
BN854_RS06035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BN854_RS06040	COG3935	DnaD domain protein
BN854_RS06045	COG0571	ribonuclease III activity
BN854_RS06050	COG0416	fatty acid biosynthetic process
BN854_RS06060	COG3425	synthase
BN854_RS06100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BN854_RS06105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BN854_RS06140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BN854_RS06150	COG0287	Prephenate dehydrogenase
BN854_RS06155	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BN854_RS06165	COG1970	mechanosensitive ion channel activity
BN854_RS06175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BN854_RS06180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BN854_RS06190	COG3481	metal-dependent phosphohydrolase, HD sub domain
BN854_RS06195	COG0617	tRNA 3'-terminal CCA addition
BN854_RS06205	COG1739	Uncharacterized protein family UPF0029
BN854_RS06220	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BN854_RS06225	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BN854_RS06230	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BN854_RS06235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BN854_RS06240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BN854_RS06245	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BN854_RS06250	COG0356	it plays a direct role in the translocation of protons across the membrane
BN854_RS06265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BN854_RS06285	COG1217	gtp-binding protein TYPA
BN854_RS06290	COG0009	L-threonylcarbamoyladenylate synthase
BN854_RS06295	COG2890	protein-(glutamine-N5) methyltransferase activity
BN854_RS06300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BN854_RS06305	COG1132	(ABC) transporter
BN854_RS06310	COG1132	(ABC) transporter
BN854_RS06315	COG0783	Belongs to the Dps family
BN854_RS06320	COG0305	Participates in initiation and elongation during chromosome replication
BN854_RS06325	COG0359	binds to the 23S rRNA
BN854_RS06325	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BN854_RS06330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BN854_RS06335	COG0629	single-stranded DNA binding
BN854_RS06340	COG0360	Binds together with S18 to 16S ribosomal RNA
BN854_RS06345	COG1546	Belongs to the CinA family
BN854_RS06345	COG1058	Belongs to the CinA family
BN854_RS06350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BN854_RS06355	COG0084	hydrolase, TatD family'
BN854_RS06360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BN854_RS06365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BN854_RS06370	COG0049	tRNA binding
BN854_RS06375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BN854_RS06385	COG0569	domain protein
BN854_RS06390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BN854_RS06415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BN854_RS06420	COG0085	RNA polymerase activity
BN854_RS06425	COG2813	Specifically methylates the guanine in position
BN854_RS06430	COG0222	ribosome binding
BN854_RS06435	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BN854_RS06440	COG0081	regulation of translation
BN854_RS06445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BN854_RS06450	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BN854_RS06455	COG2514	catechol 2,3-dioxygenase activity
BN854_RS06460	COG0250	Participates in transcription elongation, termination and antitermination
BN854_RS06475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BN854_RS06480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN854_RS06485	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BN854_RS06490	COG0215	cysteine-tRNA ligase activity
BN854_RS06500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BN854_RS06505	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BN854_RS06510	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BN854_RS06520	COG2233	PERMEase
BN854_RS06550	COG3279	Response regulator of the LytR AlgR family
BN854_RS06570	COG2252	PERMEase
BN854_RS06580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BN854_RS06585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BN854_RS06585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BN854_RS06590	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BN854_RS06595	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BN854_RS06600	COG1774	PSP1 C-terminal conserved region
BN854_RS06605	COG0470	DNA polymerase III
BN854_RS06610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BN854_RS06615	COG0101	tRNA pseudouridine synthase activity
BN854_RS06630	COG1122	ATPase activity
BN854_RS06635	COG3118	belongs to the thioredoxin family
BN854_RS06640	COG0492	ferredoxin-NADP+ reductase activity
BN854_RS06660	COG0203	ribosomal protein L17
BN854_RS06665	COG0202	RNA polymerase activity
BN854_RS06670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BN854_RS06675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BN854_RS06680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BN854_RS06685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BN854_RS06690	COG0024	Methionine aminopeptidase
BN854_RS06695	COG0563	adenylate kinase activity
BN854_RS06700	COG0201	protein transport
BN854_RS06705	COG0200	Binds to the 23S rRNA
BN854_RS06710	COG1841	ribosomal large subunit assembly
BN854_RS06715	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BN854_RS06720	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BN854_RS06725	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BN854_RS06730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BN854_RS06735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BN854_RS06740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BN854_RS06745	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BN854_RS06750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BN854_RS06755	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BN854_RS06760	COG0255	Belongs to the universal ribosomal protein uL29 family
BN854_RS06765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BN854_RS06775	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BN854_RS06780	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BN854_RS06785	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BN854_RS06790	COG0089	rRNA binding
BN854_RS06795	COG0088	Forms part of the polypeptide exit tunnel
BN854_RS06800	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BN854_RS06805	COG0051	transcription antitermination factor activity, RNA binding
BN854_RS06815	COG1846	Transcriptional regulator
BN854_RS06830	COG2084	Dehydrogenase
BN854_RS06920	COG1475	DNA binding
BN854_RS06925	COG1192	Involved in chromosome partitioning
BN854_RS06930	COG0357	Ribosomal RNA small subunit methyltransferase G
BN854_RS06935	COG0445	tRNA wobble uridine modification
BN854_RS06940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BN854_RS06955	COG0590	tRNA wobble adenosine to inosine editing
BN854_RS06960	COG1435	thymidine kinase activity
BN854_RS06965	COG0254	rRNA binding
BN854_RS06970	COG2226	methyltransferase
BN854_RS07015	COG1805	sodium ion transport
BN854_RS07020	COG4656	Part of a membrane complex involved in electron transport
BN854_RS07025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BN854_RS07030	COG0217	transcriptional regulatory protein
BN854_RS07050	COG1131	(ABC) transporter
BN854_RS07060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BN854_RS07065	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BN854_RS07075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BN854_RS07080	COG1882	Formate acetyltransferase
BN854_RS07095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BN854_RS07100	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BN854_RS07105	COG0424	maF-like protein
BN854_RS07110	COG0037	tRNA processing
BN854_RS07115	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BN854_RS07120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BN854_RS07125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BN854_RS07130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BN854_RS07155	COG0504	CTP synthase activity
BN854_RS07165	COG0688	phosphatidylethanolamine metabolic process
BN854_RS07170	COG1183	phosphatidylcholine synthase activity
BN854_RS07190	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BN854_RS07195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BN854_RS07200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BN854_RS07205	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BN854_RS07210	COG1285	pathogenesis
BN854_RS07215	COG0037	tRNA processing
BN854_RS07220	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BN854_RS07225	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BN854_RS07245	COG0395	ABC-type sugar transport system, permease component
BN854_RS07250	COG1175	transmembrane transport
BN854_RS07255	COG3842	ATPase activity
BN854_RS07265	COG1132	(ABC) transporter
BN854_RS07270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BN854_RS07310	COG0017	Asparaginyl-tRNA synthetase
BN854_RS07340	COG0594	ribonuclease P activity
BN854_RS07345	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BN854_RS07360	COG0494	nUDIX hydrolase
BN854_RS07370	COG1597	lipid kinase activity
BN854_RS07375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BN854_RS07425	COG0560	Phosphoserine phosphatase
BN854_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
BN854_RS07495	COG1269	ATP hydrolysis coupled proton transport
BN854_RS07500	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BN854_RS07510	COG1136	(ABC) transporter
BN854_RS07510	COG0577	efflux transmembrane transporter activity
BN854_RS07520	COG0706	membrane insertase activity