locus-tag	class	description
EC609_RS00020	COG4783	chaperone-mediated protein folding
EC609_RS00025	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EC609_RS00040	COG2205	protein histidine kinase activity
EC609_RS00050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EC609_RS00060	COG1295	ribonuclease BN
EC609_RS00070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EC609_RS00135	COG2030	dehydratase
EC609_RS00140	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS00155	COG0439	Biotin carboxylase
EC609_RS00160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EC609_RS00165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC609_RS00255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EC609_RS00260	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EC609_RS00265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EC609_RS00270	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EC609_RS00275	COG3344	reverse transcriptase
EC609_RS00285	COG0330	HflC and HflK could
EC609_RS00290	COG0330	HflC and HflK could
EC609_RS00295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EC609_RS00300	COG1923	regulation of RNA biosynthetic process
EC609_RS00305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EC609_RS00310	COG1160	GTP binding
EC609_RS00315	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC609_RS00320	COG2976	Protein conserved in bacteria
EC609_RS00340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EC609_RS00345	COG0105	UTP biosynthetic process
EC609_RS00350	COG0525	valine-tRNA ligase activity
EC609_RS00355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS00360	COG1126	abc transporter atp-binding protein
EC609_RS00365	COG0765	amino acid transport
EC609_RS00370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS00375	COG1396	sequence-specific DNA binding
EC609_RS00380	COG0336	Belongs to the RNA methyltransferase TrmD family
EC609_RS00385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EC609_RS00390	COG0228	four-way junction DNA binding
EC609_RS00400	COG0425	Belongs to the sulfur carrier protein TusA family
EC609_RS00405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EC609_RS00460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS00470	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EC609_RS00480	COG5285	phytanoyl-CoA dioxygenase
EC609_RS00485	COG0662	Cupin 2, conserved barrel domain protein
EC609_RS00510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EC609_RS00515	COG2358	TRAP transporter, solute receptor (TAXI family
EC609_RS00525	COG2311	Membrane
EC609_RS00550	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EC609_RS00560	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EC609_RS00565	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EC609_RS00585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EC609_RS00595	COG3391	amine dehydrogenase activity
EC609_RS00625	COG1846	Transcriptional regulator
EC609_RS00635	COG1566	PFAM secretion protein HlyD family protein
EC609_RS00640	COG2814	Major facilitator Superfamily
EC609_RS00650	COG0473	3-isopropylmalate dehydrogenase activity
EC609_RS00655	COG0433	COG0433 Predicted ATPase
EC609_RS00660	COG0217	transcriptional regulatory protein
EC609_RS00665	COG0151	Belongs to the GarS family
EC609_RS00675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EC609_RS00680	COG0799	negative regulation of ribosome biogenesis
EC609_RS00685	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EC609_RS00690	COG0424	maF-like protein
EC609_RS00695	COG1301	dicarboxylic acid transport
EC609_RS00700	COG4191	Histidine kinase
EC609_RS00705	COG2204	response regulator
EC609_RS00735	COG1530	ribonuclease E activity
EC609_RS00750	COG0475	glutathione-regulated potassium exporter activity
EC609_RS00750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC609_RS00755	COG1132	(ABC) transporter
EC609_RS00775	COG0124	histidyl-tRNA synthetase
EC609_RS00785	COG0726	polysaccharide deacetylase
EC609_RS00805	COG0726	polysaccharide deacetylase
EC609_RS00825	COG1116	anion transmembrane transporter activity
EC609_RS00830	COG0395	ABC-type sugar transport system, permease component
EC609_RS00835	COG1643	Atp-dependent helicase
EC609_RS00840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EC609_RS00840	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EC609_RS00845	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EC609_RS00855	COG0704	Plays a role in the regulation of phosphate uptake
EC609_RS00860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EC609_RS00895	COG1177	transmembrane transport
EC609_RS00900	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC609_RS00905	COG3842	ATPase activity
EC609_RS00915	COG3642	lipopolysaccharide core region biosynthetic process
EC609_RS00925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EC609_RS00945	COG4608	Belongs to the ABC transporter superfamily
EC609_RS00950	COG0444	Belongs to the ABC transporter superfamily
EC609_RS00955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EC609_RS00965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS00970	COG0601	transmembrane transport
EC609_RS00975	COG0747	negative chemotaxis
EC609_RS00995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EC609_RS01000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EC609_RS01040	COG0137	argininosuccinate synthase activity
EC609_RS01050	COG3158	transport of potassium into the cell
EC609_RS01055	COG0642	Histidine kinase
EC609_RS01085	COG0776	regulation of translation
EC609_RS01090	COG3128	pkhd-type hydroxylase
EC609_RS01095	COG0626	cystathionine gamma-synthase activity
EC609_RS01100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC609_RS01105	COG0557	exoribonuclease II activity
EC609_RS01140	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EC609_RS01145	COG2391	methyltransferase activity
EC609_RS01150	COG0069	glutamate synthase activity
EC609_RS01155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC609_RS01165	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EC609_RS01300	COG3909	cytochrome
EC609_RS01310	COG0625	glutathione transferase activity
EC609_RS01315	COG0730	response to heat
EC609_RS01320	COG0482	sulfurtransferase activity
EC609_RS01325	COG0583	DNA-binding transcription factor activity
EC609_RS01365	COG0277	FAD linked oxidase domain protein
EC609_RS01370	COG0277	FAD linked oxidase domain protein
EC609_RS01375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EC609_RS01380	COG0312	modulator of DNA gyrase
EC609_RS01420	COG0436	Aminotransferase
EC609_RS01455	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC609_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS01515	COG0181	hydroxymethylbilane synthase activity
EC609_RS01520	COG0861	Integral membrane protein TerC family
EC609_RS01525	COG0861	Integral membrane protein TerC family
EC609_RS01535	COG0045	succinate-CoA ligase (ADP-forming) activity
EC609_RS01550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EC609_RS01565	COG2137	regulation of response to DNA damage stimulus
EC609_RS01570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EC609_RS01605	COG0540	Belongs to the ATCase OTCase family
EC609_RS01655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC609_RS01690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EC609_RS01700	COG0305	Participates in initiation and elongation during chromosome replication
EC609_RS01710	COG0359	binds to the 23S rRNA
EC609_RS01715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EC609_RS01720	COG2965	DNA replication, synthesis of RNA primer
EC609_RS01725	COG0360	Binds together with S18 to 16S ribosomal RNA
EC609_RS01735	COG1469	GTP cyclohydrolase I activity
EC609_RS01745	COG0142	geranyltranstransferase activity
EC609_RS01750	COG1722	exodeoxyribonuclease VII activity
EC609_RS01760	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS01785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC609_RS01795	COG3842	ATPase activity
EC609_RS01815	COG0583	DNA-binding transcription factor activity
EC609_RS01830	COG0501	Belongs to the peptidase M48B family
EC609_RS01835	COG1760	l-serine dehydratase
EC609_RS01840	COG1283	sodium-dependent phosphate transmembrane transporter activity
EC609_RS01850	COG0428	transporter
EC609_RS01860	COG1611	Belongs to the LOG family
EC609_RS01865	COG1473	amidohydrolase
EC609_RS01870	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS01880	COG0583	DNA-binding transcription factor activity
EC609_RS01890	COG1217	gtp-binding protein TYPA
EC609_RS01895	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EC609_RS01900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EC609_RS01905	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EC609_RS01910	COG2251	uridine kinase activity
EC609_RS01910	COG0195	Participates in both transcription termination and antitermination
EC609_RS01915	COG0779	Required for maturation of 30S ribosomal subunits
EC609_RS01920	COG1187	pseudouridine synthase activity
EC609_RS01945	COG0583	DNA-binding transcription factor activity
EC609_RS01950	COG0523	cobalamin synthesis protein
EC609_RS01985	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS01995	COG0642	Histidine kinase
EC609_RS02005	COG0625	glutathione transferase activity
EC609_RS02010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EC609_RS02015	COG1047	Peptidyl-prolyl cis-trans
EC609_RS02020	COG2003	Belongs to the UPF0758 family
EC609_RS02025	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EC609_RS02030	COG3483	tryptophan 2,3-dioxygenase activity
EC609_RS02045	COG0534	Mate efflux family protein
EC609_RS02055	COG2050	protein possibly involved in aromatic compounds catabolism
EC609_RS02060	COG1024	Enoyl-CoA hydratase
EC609_RS02065	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS02070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC609_RS02075	COG2151	metal-sulfur cluster biosynthetic enzyme
EC609_RS02080	COG3396	Phenylacetate-CoA oxygenase
EC609_RS02085	COG3460	Phenylacetate-CoA oxygenase
EC609_RS02090	COG3396	Phenylacetate-CoA oxygenase
EC609_RS02095	COG3327	negative regulation of DNA-templated transcription, initiation
EC609_RS02100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EC609_RS02125	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EC609_RS02130	COG0501	Belongs to the peptidase M48B family
EC609_RS02135	COG1162	GTPase activity
EC609_RS02145	COG0335	large ribosomal subunit rRNA binding
EC609_RS02175	COG0175	sulfate reduction
EC609_RS02180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EC609_RS02185	COG4208	sulfate ABC transporter
EC609_RS02195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EC609_RS02200	COG0450	alkyl hydroperoxide reductase
EC609_RS02205	COG1960	acyl-CoA dehydrogenase activity
EC609_RS02215	COG1024	Enoyl-CoA hydratase
EC609_RS02215	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS02220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS02230	COG2985	domain, Protein
EC609_RS02255	COG0123	including yeast histone deacetylase and acetoin utilization protein
EC609_RS02260	COG2951	lytic endotransglycosylase activity
EC609_RS02290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC609_RS02295	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EC609_RS02300	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EC609_RS02320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EC609_RS02325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EC609_RS02330	COG0287	Prephenate dehydrogenase
EC609_RS02335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EC609_RS02340	COG0077	Prephenate dehydratase
EC609_RS02340	COG1605	Chorismate mutase
EC609_RS02345	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EC609_RS02360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EC609_RS02415	COG2833	Protein of unknown function (DUF455)
EC609_RS02430	COG1132	(ABC) transporter
EC609_RS02435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EC609_RS02435	COG0189	ligase activity
EC609_RS02445	COG3237	CsbD-like
EC609_RS02485	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
EC609_RS02490	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS02495	COG3243	poly(R)-hydroxyalkanoic acid synthase
EC609_RS02500	COG1496	oxidoreductase activity
EC609_RS02505	COG0564	pseudouridine synthase activity
EC609_RS02525	COG1199	ATP-dependent helicase activity
EC609_RS02530	COG2183	response to ionizing radiation
EC609_RS02535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS02540	COG1116	anion transmembrane transporter activity
EC609_RS02555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC609_RS02565	COG1414	Transcriptional regulator
EC609_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS02575	COG0028	Belongs to the TPP enzyme family
EC609_RS02580	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
EC609_RS02585	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS02615	COG4774	siderophore transport
EC609_RS02620	COG3712	iron ion homeostasis
EC609_RS02625	COG1595	DNA-templated transcription, initiation
EC609_RS02630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EC609_RS02635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC609_RS02640	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC609_RS02645	COG0567	Dehydrogenase, E1 component
EC609_RS02675	COG1297	OPT oligopeptide transporter protein
EC609_RS02685	COG0281	malic enzyme
EC609_RS02685	COG0280	phosphate acetyltransferase
EC609_RS02740	COG0372	Belongs to the citrate synthase family
EC609_RS02745	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EC609_RS02750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EC609_RS02755	COG1053	succinate dehydrogenase
EC609_RS02760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EC609_RS02765	COG2009	succinate dehydrogenase
EC609_RS02770	COG2188	Transcriptional regulator
EC609_RS02795	COG1981	membrane
EC609_RS02840	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EC609_RS02855	COG0148	phosphopyruvate hydratase activity
EC609_RS02870	COG0504	CTP synthase activity
EC609_RS02895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS02905	COG0747	negative chemotaxis
EC609_RS02910	COG4172	Belongs to the ABC transporter superfamily
EC609_RS02915	COG1446	asparaginase
EC609_RS02925	COG2153	protein acetylation
EC609_RS02970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EC609_RS02975	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EC609_RS02980	COG0697	spore germination
EC609_RS02985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EC609_RS03005	COG0791	NLP P60 protein
EC609_RS03015	COG0583	DNA-binding transcription factor activity
EC609_RS03040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EC609_RS03070	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS03080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EC609_RS03090	COG1381	Involved in DNA repair and RecF pathway recombination
EC609_RS03095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EC609_RS03100	COG0571	ribonuclease III activity
EC609_RS03105	COG0681	Belongs to the peptidase S26 family
EC609_RS03115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC609_RS03140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EC609_RS03145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EC609_RS03150	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS03155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EC609_RS03160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EC609_RS03165	COG0416	fatty acid biosynthetic process
EC609_RS03170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EC609_RS03175	COG1399	metal-binding, possibly nucleic acid-binding protein
EC609_RS03180	COG0424	maF-like protein
EC609_RS03190	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC609_RS03195	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EC609_RS03200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EC609_RS03205	COG0546	phosphoglycolate phosphatase activity
EC609_RS03215	COG1530	ribonuclease E activity
EC609_RS03230	COG2721	sulfolactate sulfo-lyase activity
EC609_RS03240	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EC609_RS03245	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EC609_RS03250	COG0159	tryptophan synthase activity
EC609_RS03270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC609_RS03275	COG3228	Belongs to the MtfA family
EC609_RS03280	COG0655	NAD(P)H dehydrogenase (quinone) activity
EC609_RS03285	COG0251	oxidation-reduction process
EC609_RS03310	COG2878	Part of a membrane complex involved in electron transport
EC609_RS03315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EC609_RS03385	COG1268	BioY protein
EC609_RS03390	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EC609_RS03395	COG1122	ATPase activity
EC609_RS03400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EC609_RS03405	COG2917	probably involved in intracellular septation
EC609_RS03415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC609_RS03420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EC609_RS03430	COG1196	nuclear chromosome segregation
EC609_RS03435	COG0477	Major facilitator Superfamily
EC609_RS03440	COG1573	uracil-dna glycosylase
EC609_RS03460	COG0450	alkyl hydroperoxide reductase
EC609_RS03465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC609_RS03470	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EC609_RS03475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EC609_RS03485	COG0560	Phosphoserine phosphatase
EC609_RS03490	COG4774	siderophore transport
EC609_RS03500	COG1007	ATP synthesis coupled electron transport
EC609_RS03515	COG0713	ATP synthesis coupled electron transport
EC609_RS03525	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC609_RS03530	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EC609_RS03535	COG1034	ATP synthesis coupled electron transport
EC609_RS03545	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EC609_RS03555	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC609_RS03560	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC609_RS03565	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC609_RS03570	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC609_RS03595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EC609_RS03600	COG1597	lipid kinase activity
EC609_RS03630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC609_RS03650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC609_RS03655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC609_RS03660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EC609_RS03710	COG4172	Belongs to the ABC transporter superfamily
EC609_RS03730	COG2354	Protein conserved in bacteria
EC609_RS03735	COG3813	Protein conserved in bacteria
EC609_RS03745	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EC609_RS03750	COG3604	Transcriptional regulator
EC609_RS03760	COG0604	alcohol dehydrogenase
EC609_RS03765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS03770	COG0583	DNA-binding transcription factor activity
EC609_RS03775	COG0583	DNA-binding transcription factor activity
EC609_RS03790	COG4172	Belongs to the ABC transporter superfamily
EC609_RS03795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS03800	COG0601	transmembrane transport
EC609_RS03810	COG3119	arylsulfatase activity
EC609_RS03815	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS03820	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS03825	COG2851	Citrate transporter
EC609_RS03865	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS03880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EC609_RS03955	COG1116	anion transmembrane transporter activity
EC609_RS04020	COG0006	proline dipeptidase activity
EC609_RS04030	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC609_RS04040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EC609_RS04045	COG0583	DNA-binding transcription factor activity
EC609_RS04055	COG0583	DNA-binding transcription factor activity
EC609_RS04070	COG2814	Major facilitator Superfamily
EC609_RS04075	COG1335	isochorismatase
EC609_RS04085	COG1802	Transcriptional regulator
EC609_RS04100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS04105	COG1024	Enoyl-CoA hydratase
EC609_RS04115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS04145	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS04155	COG2267	carboxylic ester hydrolase activity
EC609_RS04165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EC609_RS04165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EC609_RS04170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EC609_RS04170	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EC609_RS04175	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS04210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EC609_RS04230	COG1024	Enoyl-CoA hydratase
EC609_RS04250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EC609_RS04260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS04265	COG2030	dehydratase
EC609_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS04290	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS04300	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS04345	COG0583	DNA-binding transcription factor activity
EC609_RS04360	COG0251	oxidation-reduction process
EC609_RS04365	COG0583	DNA-binding transcription factor activity
EC609_RS04380	COG2084	Dehydrogenase
EC609_RS04405	COG0583	DNA-binding transcription factor activity
EC609_RS04415	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS04420	COG0028	Belongs to the TPP enzyme family
EC609_RS04425	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS04430	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS04440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC609_RS04475	COG5383	Protein conserved in bacteria
EC609_RS04480	COG0583	DNA-binding transcription factor activity
EC609_RS04510	COG0647	UMP catabolic process
EC609_RS04515	COG1737	Transcriptional regulator
EC609_RS04520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EC609_RS04525	COG0149	triose-phosphate isomerase activity
EC609_RS04540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC609_RS04545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC609_RS04550	COG2010	Cytochrome c
EC609_RS04570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EC609_RS04595	COG2010	Cytochrome c
EC609_RS04600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EC609_RS04600	COG1648	precorrin-2 dehydrogenase activity
EC609_RS04635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EC609_RS04645	COG1185	polyribonucleotide nucleotidyltransferase activity
EC609_RS04650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EC609_RS04660	COG1183	phosphatidylcholine synthase activity
EC609_RS04665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EC609_RS04670	COG0440	acetolactate synthase activity
EC609_RS04675	COG0028	Belongs to the TPP enzyme family
EC609_RS04680	COG1289	transmembrane transporter activity
EC609_RS04685	COG3022	response to hydroperoxide
EC609_RS04705	COG0582	viral genome integration into host DNA
EC609_RS04720	COG4983	Phage plasmid primase, P4 family domain protein
EC609_RS04785	COG1196	nuclear chromosome segregation
EC609_RS04810	COG5377	YqaJ viral recombinase family
EC609_RS04845	COG2885	chlorophyll binding
EC609_RS04850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC609_RS04855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC609_RS04860	COG0477	Major facilitator Superfamily
EC609_RS04870	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EC609_RS04920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EC609_RS04925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EC609_RS04930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC609_RS04965	COG0517	IMP dehydrogenase activity
EC609_RS04965	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EC609_RS04970	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EC609_RS04980	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EC609_RS04985	COG1674	ftsk spoiiie
EC609_RS04990	COG0492	ferredoxin-NADP+ reductase activity
EC609_RS04995	COG1193	negative regulation of DNA recombination
EC609_RS05005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC609_RS05020	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EC609_RS05025	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EC609_RS05030	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EC609_RS05035	COG2205	protein histidine kinase activity
EC609_RS05040	COG0745	RESPONSE REGULATOR receiver
EC609_RS05055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC609_RS05060	COG0840	transmembrane signaling receptor activity
EC609_RS05090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EC609_RS05115	COG0612	Peptidase, M16
EC609_RS05125	COG0484	heat shock protein binding
EC609_RS05130	COG0443	Heat shock 70 kDa protein
EC609_RS05140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EC609_RS05150	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EC609_RS05165	COG0497	DNA recombination
EC609_RS05170	COG0735	belongs to the Fur family
EC609_RS05175	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC609_RS05205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS05220	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS05230	COG1063	alcohol dehydrogenase
EC609_RS05235	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
EC609_RS05235	COG0028	Belongs to the TPP enzyme family
EC609_RS05260	COG0583	DNA-binding transcription factor activity
EC609_RS05270	COG1473	amidohydrolase
EC609_RS05305	COG1304	FMN binding
EC609_RS05320	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EC609_RS05325	COG0463	Glycosyl transferase, family 2
EC609_RS05335	COG1368	sulfuric ester hydrolase activity
EC609_RS05350	COG0586	Pfam SNARE associated Golgi protein
EC609_RS05360	COG0463	Glycosyl transferase, family 2
EC609_RS05385	COG1396	sequence-specific DNA binding
EC609_RS05390	COG0583	DNA-binding transcription factor activity
EC609_RS05430	COG2132	Multicopper oxidase
EC609_RS05435	COG0745	RESPONSE REGULATOR receiver
EC609_RS05440	COG5002	protein histidine kinase activity
EC609_RS05445	COG2433	Pfam Transposase IS66
EC609_RS05465	COG0640	Transcriptional regulator
EC609_RS05480	COG0798	PFAM Bile acid sodium symporter
EC609_RS05490	COG1695	Transcriptional regulator
EC609_RS05570	COG2003	Belongs to the UPF0758 family
EC609_RS05625	COG3311	Transcriptional regulator
EC609_RS05630	COG1569	PIN domain
EC609_RS05635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EC609_RS05705	COG3344	reverse transcriptase
EC609_RS05795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EC609_RS05805	COG0789	Transcriptional regulator
EC609_RS05825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC609_RS05830	COG0629	single-stranded DNA binding
EC609_RS05925	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EC609_RS05930	COG0167	dihydroorotate dehydrogenase activity
EC609_RS05945	COG1414	Transcriptional regulator
EC609_RS05950	COG1058	Belongs to the CinA family
EC609_RS05950	COG1546	Belongs to the CinA family
EC609_RS05965	COG0513	Belongs to the DEAD box helicase family
EC609_RS05995	COG0429	hydrolase of the alpha beta-hydrolase fold
EC609_RS06000	COG4783	chaperone-mediated protein folding
EC609_RS06015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC609_RS06020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EC609_RS06040	COG0006	proline dipeptidase activity
EC609_RS06050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC609_RS06070	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EC609_RS06075	COG0632	four-way junction helicase activity
EC609_RS06080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC609_RS06110	COG0514	ATP-dependent DNA helicase (RecQ)
EC609_RS06115	COG1294	oxidase, subunit
EC609_RS06125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EC609_RS06135	COG0850	regulation of cytokinetic process
EC609_RS06140	COG2894	cell division
EC609_RS06145	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EC609_RS06160	COG0488	(ABC) transporter
EC609_RS06180	COG4608	Belongs to the ABC transporter superfamily
EC609_RS06185	COG0444	Belongs to the ABC transporter superfamily
EC609_RS06190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS06195	COG0601	transmembrane transport
EC609_RS06200	COG0747	negative chemotaxis
EC609_RS06225	COG4638	Rieske (2fe-2S)
EC609_RS06250	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EC609_RS06255	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS06280	COG1216	Glycosyl transferase, family 2
EC609_RS06280	COG0463	Glycosyl transferase, family 2
EC609_RS06305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EC609_RS06350	COG0577	efflux transmembrane transporter activity
EC609_RS06350	COG1136	(ABC) transporter
EC609_RS06355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC609_RS06370	COG0259	pyridoxamine-phosphate oxidase activity
EC609_RS06380	COG0579	oxidoreductase
EC609_RS06390	COG0659	secondary active sulfate transmembrane transporter activity
EC609_RS06395	COG0583	DNA-binding transcription factor activity
EC609_RS06400	COG1960	acyl-CoA dehydrogenase activity
EC609_RS06405	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS06425	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS06450	COG0860	N-Acetylmuramoyl-L-alanine amidase
EC609_RS06455	COG0586	Pfam SNARE associated Golgi protein
EC609_RS06465	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EC609_RS06470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EC609_RS06485	COG0617	tRNA 3'-terminal CCA addition
EC609_RS06495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC609_RS06500	COG2301	Belongs to the HpcH HpaI aldolase family
EC609_RS06505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS06510	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
EC609_RS06520	COG1024	Enoyl-CoA hydratase
EC609_RS06530	COG1960	acyl-CoA dehydrogenase activity
EC609_RS06540	COG0183	Belongs to the thiolase family
EC609_RS06545	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS06565	COG0583	DNA-binding transcription factor activity
EC609_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS06575	COG2030	dehydratase
EC609_RS06590	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS06595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC609_RS06600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC609_RS06610	COG1024	Enoyl-CoA hydratase
EC609_RS06615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EC609_RS06620	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS06635	COG0752	glycyl-tRNA synthetase alpha subunit
EC609_RS06640	COG0751	glycine-tRNA ligase activity
EC609_RS06645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EC609_RS06650	COG0204	Acyl-transferase
EC609_RS06670	COG0242	peptide deformylase activity
EC609_RS06675	COG1960	acyl-CoA dehydrogenase activity
EC609_RS06680	COG0700	Nucleoside recognition
EC609_RS06685	COG0469	pyruvate kinase activity
EC609_RS06690	COG1929	Belongs to the glycerate kinase type-1 family
EC609_RS06700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC609_RS06715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EC609_RS06740	COG2154	pterin-4-alpha-carbinolamine dehydratase
EC609_RS06775	COG2814	Major facilitator Superfamily
EC609_RS06800	COG0601	transmembrane transport
EC609_RS06810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EC609_RS06815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EC609_RS06820	COG1802	Transcriptional regulator
EC609_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS06865	COG2982	Protein involved in outer membrane biogenesis
EC609_RS06870	COG1368	sulfuric ester hydrolase activity
EC609_RS06875	COG2818	Glycosylase
EC609_RS06890	COG0735	belongs to the Fur family
EC609_RS06905	COG1335	isochorismatase
EC609_RS06910	COG0583	DNA-binding transcription factor activity
EC609_RS06920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC609_RS06925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EC609_RS06930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EC609_RS06930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EC609_RS06940	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS06960	COG2011	ABC-type metal ion transport system permease component
EC609_RS06965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EC609_RS06970	COG1501	Belongs to the glycosyl hydrolase 31 family
EC609_RS06975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS06975	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EC609_RS06985	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS06990	COG1473	amidohydrolase
EC609_RS07000	COG2855	membrane
EC609_RS07010	COG2239	Acts as a magnesium transporter
EC609_RS07025	COG1522	sequence-specific DNA binding
EC609_RS07030	COG0300	oxidoreductase activity
EC609_RS07040	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS07055	COG0653	protein targeting
EC609_RS07060	COG0739	heme binding
EC609_RS07070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EC609_RS07075	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EC609_RS07095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EC609_RS07110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EC609_RS07115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC609_RS07120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EC609_RS07130	COG3116	cell division
EC609_RS07135	COG0275	rRNA processing
EC609_RS07140	COG2001	Belongs to the MraZ family
EC609_RS07150	COG0488	(ABC) transporter
EC609_RS07160	COG0418	dihydroorotase activity
EC609_RS07165	COG1473	amidohydrolase
EC609_RS07175	COG0583	DNA-binding transcription factor activity
EC609_RS07245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EC609_RS07250	COG4654	Cytochrome c, class I
EC609_RS07255	COG0129	dihydroxy-acid dehydratase activity
EC609_RS07300	COG2084	Dehydrogenase
EC609_RS07315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC609_RS07350	COG0824	Thioesterase
EC609_RS07360	COG0848	biopolymer transport protein
EC609_RS07370	COG0823	Involved in the tonB-independent uptake of proteins
EC609_RS07385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC609_RS07390	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EC609_RS07405	COG1522	sequence-specific DNA binding
EC609_RS07415	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EC609_RS07435	COG0697	spore germination
EC609_RS07445	COG1346	cytolysis
EC609_RS07455	COG0583	DNA-binding transcription factor activity
EC609_RS07470	COG0583	DNA-binding transcription factor activity
EC609_RS07485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EC609_RS07490	COG0463	Glycosyl transferase, family 2
EC609_RS07500	COG0786	glutamate:sodium symporter activity
EC609_RS07515	COG1671	Belongs to the UPF0178 family
EC609_RS07525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC609_RS07530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC609_RS07540	COG0328	RNA-DNA hybrid ribonuclease activity
EC609_RS07545	COG2226	methyltransferase
EC609_RS07550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EC609_RS07575	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS07595	COG1366	Belongs to the anti-sigma-factor antagonist family
EC609_RS07600	COG2172	sigma factor antagonist activity
EC609_RS07615	COG2208	phosphoserine phosphatase activity
EC609_RS07615	COG2770	Histidine kinase
EC609_RS07645	COG4792	protein secretion
EC609_RS07650	COG4791	protein targeting
EC609_RS07655	COG4794	Type iii secretion
EC609_RS07660	COG4790	Type iii secretion
EC609_RS07665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EC609_RS07765	COG4789	Type iii secretion
EC609_RS07800	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS07820	COG2719	SpoVR family
EC609_RS07825	COG2718	Belongs to the UPF0229 family
EC609_RS07830	COG2766	serine protein kinase
EC609_RS07835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC609_RS07835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC609_RS07845	COG2207	Transcriptional regulator
EC609_RS07850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EC609_RS07855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EC609_RS07860	COG1280	lysine exporter protein (LysE YggA)
EC609_RS07870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EC609_RS07880	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EC609_RS07885	COG0316	Belongs to the HesB IscA family
EC609_RS07895	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EC609_RS07900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EC609_RS07905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EC609_RS07920	COG4177	L-phenylalanine transmembrane transporter activity
EC609_RS07925	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC609_RS07940	COG0312	modulator of DNA gyrase
EC609_RS07945	COG3028	Belongs to the UPF0307 family
EC609_RS07960	COG1116	anion transmembrane transporter activity
EC609_RS07965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS07970	COG1335	isochorismatase
EC609_RS07980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EC609_RS07985	COG0477	Major facilitator Superfamily
EC609_RS08010	COG1522	sequence-specific DNA binding
EC609_RS08035	COG0762	integral membrane protein
EC609_RS08040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EC609_RS08045	COG1696	Membrane protein involved in D-alanine export
EC609_RS08070	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EC609_RS08070	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EC609_RS08080	COG2264	protein methyltransferase activity
EC609_RS08085	COG0439	Biotin carboxylase
EC609_RS08090	COG0511	ligase activity, forming carbon-carbon bonds
EC609_RS08095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EC609_RS08105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EC609_RS08110	COG3150	esterase
EC609_RS08115	COG0557	exoribonuclease II activity
EC609_RS08135	COG1175	transmembrane transport
EC609_RS08150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EC609_RS08155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EC609_RS08170	COG1126	abc transporter atp-binding protein
EC609_RS08175	COG0765	amino acid transport
EC609_RS08185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS08195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC609_RS08215	COG0540	Belongs to the ATCase OTCase family
EC609_RS08220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EC609_RS08225	COG1678	Uncharacterized ACR, COG1678
EC609_RS08235	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EC609_RS08235	COG0352	thiamine-phosphate diphosphorylase activity
EC609_RS08235	COG0351	phosphomethylpyrimidine kinase
EC609_RS08240	COG0352	thiamine-phosphate diphosphorylase activity
EC609_RS08250	COG0741	lytic transglycosylase activity
EC609_RS08260	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS08265	COG1335	isochorismatase
EC609_RS08275	COG4638	Rieske (2fe-2S)
EC609_RS08290	COG2207	Transcriptional regulator
EC609_RS08315	COG1024	Enoyl-CoA hydratase
EC609_RS08320	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS08430	COG0583	DNA-binding transcription factor activity
EC609_RS08440	COG0154	amidase activity
EC609_RS08460	COG4774	siderophore transport
EC609_RS08475	COG0583	DNA-binding transcription factor activity
EC609_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS08495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC609_RS08510	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EC609_RS08535	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EC609_RS08540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EC609_RS08600	COG4214	carbohydrate transport
EC609_RS08615	COG0028	Belongs to the TPP enzyme family
EC609_RS08620	COG1802	Transcriptional regulator
EC609_RS08645	COG4771	TonB-dependent receptor
EC609_RS08650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EC609_RS08655	COG2022	thiamine diphosphate biosynthetic process
EC609_RS08660	COG0351	phosphomethylpyrimidine kinase
EC609_RS08665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EC609_RS08675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EC609_RS08685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EC609_RS08700	COG2226	methyltransferase
EC609_RS08705	COG0745	RESPONSE REGULATOR receiver
EC609_RS08710	COG5002	protein histidine kinase activity
EC609_RS08725	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EC609_RS08730	COG2132	Multicopper oxidase
EC609_RS08765	COG1984	allophanate hydrolase subunit 2
EC609_RS08775	COG1802	Transcriptional regulator
EC609_RS08780	COG2860	membrane
EC609_RS08790	COG2223	nitrite transmembrane transporter activity
EC609_RS08795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EC609_RS08795	COG2813	Specifically methylates the guanine in position
EC609_RS08800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EC609_RS08805	COG2188	Transcriptional regulator
EC609_RS08810	COG2721	sulfolactate sulfo-lyase activity
EC609_RS08815	COG2721	sulfolactate sulfo-lyase activity
EC609_RS08825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC609_RS08830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EC609_RS08855	COG2918	glutathione biosynthetic process
EC609_RS08875	COG0583	DNA-binding transcription factor activity
EC609_RS08880	COG1802	Transcriptional regulator
EC609_RS08885	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC609_RS08900	COG2197	response regulator
EC609_RS08905	COG0784	Response regulator, receiver
EC609_RS08905	COG2205	protein histidine kinase activity
EC609_RS08915	COG0784	Response regulator, receiver
EC609_RS08915	COG2205	protein histidine kinase activity
EC609_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS08935	COG3246	L-lysine catabolic process to acetate
EC609_RS08965	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS09065	COG3504	Conjugal transfer protein
EC609_RS09105	COG1674	ftsk spoiiie
EC609_RS09120	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EC609_RS09140	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS09145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC609_RS09155	COG0583	DNA-binding transcription factor activity
EC609_RS09200	COG3093	addiction module antidote protein HigA
EC609_RS09265	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EC609_RS09280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EC609_RS09290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EC609_RS09295	COG0581	inorganic phosphate transmembrane transporter activity
EC609_RS09300	COG0573	inorganic phosphate transmembrane transporter activity
EC609_RS09305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EC609_RS09315	COG0640	Transcriptional regulator
EC609_RS09335	COG0431	NADPH-dependent FMN reductase
EC609_RS09345	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
EC609_RS09360	COG4191	Histidine kinase
EC609_RS09445	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS09460	COG1309	transcriptional regulator
EC609_RS09470	COG1024	Enoyl-CoA hydratase
EC609_RS09475	COG1024	Enoyl-CoA hydratase
EC609_RS09490	COG0747	negative chemotaxis
EC609_RS09495	COG0583	DNA-binding transcription factor activity
EC609_RS09500	COG2988	succinylglutamate desuccinylase activity
EC609_RS09505	COG0747	negative chemotaxis
EC609_RS09510	COG0601	transmembrane transport
EC609_RS09515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS09520	COG0444	Belongs to the ABC transporter superfamily
EC609_RS09525	COG4608	Belongs to the ABC transporter superfamily
EC609_RS09535	COG2195	Cleaves the N-terminal amino acid of tripeptides
EC609_RS09545	COG2171	N-acyltransferase activity
EC609_RS09555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EC609_RS09560	COG0210	DNA helicase
EC609_RS09565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EC609_RS09570	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EC609_RS09580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EC609_RS09590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EC609_RS09595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EC609_RS09600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EC609_RS09615	COG0356	it plays a direct role in the translocation of protons across the membrane
EC609_RS09635	COG1024	Enoyl-CoA hydratase
EC609_RS09645	COG0583	DNA-binding transcription factor activity
EC609_RS09650	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS09655	COG3473	Maleate cis-trans isomerase
EC609_RS09660	COG0583	DNA-binding transcription factor activity
EC609_RS09665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EC609_RS09675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC609_RS09700	COG0037	tRNA processing
EC609_RS09705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC609_RS09715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC609_RS09720	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EC609_RS09725	COG2967	ApaG domain
EC609_RS09730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EC609_RS09735	COG0546	phosphoglycolate phosphatase activity
EC609_RS09745	COG0512	Glutamine amidotransferase of anthranilate synthase
EC609_RS09750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EC609_RS09755	COG0134	indole-3-glycerol-phosphate synthase activity
EC609_RS09760	COG3284	Transcriptional regulator
EC609_RS09765	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS09785	COG0583	DNA-binding transcription factor activity
EC609_RS09795	COG1305	Transglutaminase-like
EC609_RS09800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC609_RS09825	COG2864	formate dehydrogenase
EC609_RS09830	COG0437	4 iron, 4 sulfur cluster binding
EC609_RS09835	COG0243	molybdopterin cofactor binding
EC609_RS09835	COG3383	formate dehydrogenase (NAD+) activity
EC609_RS09840	COG0243	molybdopterin cofactor binding
EC609_RS09840	COG3383	formate dehydrogenase (NAD+) activity
EC609_RS09850	COG1607	acyl-coa hydrolase
EC609_RS09885	COG3064	Membrane
EC609_RS09890	COG3585	molybdate ion transport
EC609_RS09915	COG3069	C4-dicarboxylate transmembrane transporter activity
EC609_RS09925	COG1802	Transcriptional regulator
EC609_RS09975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EC609_RS09980	COG1473	amidohydrolase
EC609_RS09985	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS09990	COG0583	DNA-binding transcription factor activity
EC609_RS09995	COG2814	Major facilitator Superfamily
EC609_RS10035	COG2188	Transcriptional regulator
EC609_RS10050	COG0438	transferase activity, transferring glycosyl groups
EC609_RS10060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EC609_RS10065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EC609_RS10085	COG2423	ornithine cyclodeaminase activity
EC609_RS10090	COG1522	sequence-specific DNA binding
EC609_RS10100	COG2423	ornithine cyclodeaminase activity
EC609_RS10110	COG0583	DNA-binding transcription factor activity
EC609_RS10120	COG0583	DNA-binding transcription factor activity
EC609_RS10125	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS10130	COG0154	amidase activity
EC609_RS10160	COG0484	heat shock protein binding
EC609_RS10170	COG0861	Integral membrane protein TerC family
EC609_RS10175	COG0477	Major facilitator Superfamily
EC609_RS10185	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS10190	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS10200	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS10210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC609_RS10220	COG2188	Transcriptional regulator
EC609_RS10250	COG1522	sequence-specific DNA binding
EC609_RS10265	COG2814	Major facilitator Superfamily
EC609_RS10270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EC609_RS10290	COG1999	signal sequence binding
EC609_RS10300	COG1612	heme a metabolic process
EC609_RS10330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EC609_RS10355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EC609_RS10380	COG0070	glutamate synthase
EC609_RS10380	COG0069	glutamate synthase activity
EC609_RS10380	COG0067	glutamate synthase
EC609_RS10395	COG0583	DNA-binding transcription factor activity
EC609_RS10400	COG0477	Major facilitator Superfamily
EC609_RS10410	COG2070	2-Nitropropane dioxygenase
EC609_RS10415	COG1127	ABC transporter
EC609_RS10420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EC609_RS10425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EC609_RS10430	COG2853	Lipoprotein
EC609_RS10440	COG1131	(ABC) transporter
EC609_RS10445	COG0842	Transport permease protein
EC609_RS10450	COG0271	Belongs to the BolA IbaG family
EC609_RS10455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EC609_RS10460	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EC609_RS10465	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EC609_RS10470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EC609_RS10475	COG0131	Imidazoleglycerol-phosphate dehydratase
EC609_RS10480	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EC609_RS10485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EC609_RS10490	COG0107	imidazoleglycerol-phosphate synthase activity
EC609_RS10500	COG0140	phosphoribosyl-ATP diphosphatase activity
EC609_RS10505	COG0537	adenosine 5'-monophosphoramidase activity
EC609_RS10510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EC609_RS10515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EC609_RS10545	COG0477	Major facilitator Superfamily
EC609_RS10555	COG0235	Class ii aldolase
EC609_RS10560	COG1970	mechanosensitive ion channel activity
EC609_RS10565	COG0723	plastoquinol--plastocyanin reductase activity
EC609_RS10570	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EC609_RS10575	COG2857	Cytochrome c1
EC609_RS10580	COG0625	glutathione transferase activity
EC609_RS10585	COG2969	positive regulation of protein catabolic process
EC609_RS10655	COG0747	negative chemotaxis
EC609_RS10660	COG0601	transmembrane transport
EC609_RS10670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS10680	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EC609_RS10685	COG5339	Protein conserved in bacteria
EC609_RS10690	COG0513	Belongs to the DEAD box helicase family
EC609_RS10695	COG1280	lysine exporter protein (LysE YggA)
EC609_RS10700	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EC609_RS10720	COG0583	DNA-binding transcription factor activity
EC609_RS10730	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EC609_RS10740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EC609_RS10750	COG1609	Transcriptional regulator
EC609_RS10755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EC609_RS10760	COG3842	ATPase activity
EC609_RS10765	COG1653	transport
EC609_RS10770	COG1175	transmembrane transport
EC609_RS10775	COG0395	ABC-type sugar transport system, permease component
EC609_RS10780	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS10790	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EC609_RS10820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EC609_RS10830	COG0778	Nitroreductase
EC609_RS10855	COG1473	amidohydrolase
EC609_RS10860	COG1960	acyl-CoA dehydrogenase activity
EC609_RS10865	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EC609_RS10870	COG0183	Belongs to the thiolase family
EC609_RS10875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EC609_RS10895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS10905	COG0492	ferredoxin-NADP+ reductase activity
EC609_RS10910	COG0583	DNA-binding transcription factor activity
EC609_RS10945	COG2985	domain, Protein
EC609_RS10960	COG0668	transmembrane transport
EC609_RS10975	COG0693	protein deglycase activity
EC609_RS11050	COG1595	DNA-templated transcription, initiation
EC609_RS11055	COG3712	iron ion homeostasis
EC609_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS11155	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS11160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EC609_RS11190	COG2358	TRAP transporter, solute receptor (TAXI family
EC609_RS11200	COG2922	Belongs to the Smg family
EC609_RS11225	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EC609_RS11230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS11240	COG0028	Belongs to the TPP enzyme family
EC609_RS11245	COG1522	sequence-specific DNA binding
EC609_RS11250	COG3781	membrane
EC609_RS11265	COG2814	Major facilitator Superfamily
EC609_RS11280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC609_RS11295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EC609_RS11305	COG1744	ABC transporter substrate-binding protein PnrA-like
EC609_RS11310	COG3845	ABC transporter
EC609_RS11315	COG4603	Belongs to the binding-protein-dependent transport system permease family
EC609_RS11325	COG0402	S-adenosylhomocysteine deaminase activity
EC609_RS11330	COG0251	oxidation-reduction process
EC609_RS11355	COG1177	transmembrane transport
EC609_RS11360	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC609_RS11365	COG3842	ATPase activity
EC609_RS11390	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS11415	COG1304	FMN binding
EC609_RS11445	COG0765	amino acid transport
EC609_RS11450	COG0765	amino acid transport
EC609_RS11455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS11465	COG2186	Transcriptional regulator
EC609_RS11470	COG0129	dihydroxy-acid dehydratase activity
EC609_RS11475	COG0477	Major facilitator Superfamily
EC609_RS11485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC609_RS11510	COG1917	Cupin 2, conserved barrel domain protein
EC609_RS11515	COG0154	amidase activity
EC609_RS11520	COG1126	abc transporter atp-binding protein
EC609_RS11535	COG0592	DNA-directed DNA polymerase activity
EC609_RS11540	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EC609_RS11545	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EC609_RS11550	COG0594	ribonuclease P activity
EC609_RS11555	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EC609_RS11565	COG0753	catalase activity
EC609_RS11575	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EC609_RS11585	COG2175	clavaminate synthase activity
EC609_RS11595	COG4608	Belongs to the ABC transporter superfamily
EC609_RS11600	COG0444	Belongs to the ABC transporter superfamily
EC609_RS11605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS11610	COG0601	transmembrane transport
EC609_RS11620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EC609_RS11655	COG0038	chloride channel
EC609_RS11685	COG0436	Aminotransferase
EC609_RS11690	COG3180	Ammonia monooxygenase
EC609_RS11695	COG1278	Cold shock
EC609_RS11700	COG0445	tRNA wobble uridine modification
EC609_RS11705	COG0357	Ribosomal RNA small subunit methyltransferase G
EC609_RS11710	COG1192	Involved in chromosome partitioning
EC609_RS11720	COG1475	DNA binding
EC609_RS11725	COG0252	asparaginase activity
EC609_RS11730	COG0583	DNA-binding transcription factor activity
EC609_RS11755	COG1349	DNA-binding transcription factor activity
EC609_RS11765	COG3842	ATPase activity
EC609_RS11770	COG1840	ABC-type Fe3 transport system, periplasmic component
EC609_RS11785	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS11810	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EC609_RS11820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EC609_RS11835	COG0081	regulation of translation
EC609_RS11840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EC609_RS11845	COG0222	ribosome binding
EC609_RS11850	COG0085	RNA polymerase activity
EC609_RS11855	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EC609_RS11885	COG0745	RESPONSE REGULATOR receiver
EC609_RS11890	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EC609_RS11895	COG0049	tRNA binding
EC609_RS11905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EC609_RS11910	COG0051	transcription antitermination factor activity, RNA binding
EC609_RS11915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EC609_RS11925	COG0089	rRNA binding
EC609_RS11930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EC609_RS11935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EC609_RS11940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EC609_RS11945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EC609_RS11950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EC609_RS11955	COG0255	Belongs to the universal ribosomal protein uL29 family
EC609_RS11960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EC609_RS11975	COG4177	L-phenylalanine transmembrane transporter activity
EC609_RS11980	COG1126	abc transporter atp-binding protein
EC609_RS12000	COG2207	Transcriptional regulator
EC609_RS12025	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EC609_RS12030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EC609_RS12035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EC609_RS12040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EC609_RS12045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EC609_RS12050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EC609_RS12055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EC609_RS12060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EC609_RS12065	COG1841	ribosomal large subunit assembly
EC609_RS12070	COG0200	Binds to the 23S rRNA
EC609_RS12075	COG0201	protein transport
EC609_RS12080	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EC609_RS12085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EC609_RS12090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EC609_RS12095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EC609_RS12100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EC609_RS12105	COG0202	RNA polymerase activity
EC609_RS12110	COG0203	ribosomal protein L17
EC609_RS12120	COG1324	tolerance protein
EC609_RS12125	COG4232	protein-disulfide reductase activity
EC609_RS12135	COG1053	succinate dehydrogenase
EC609_RS12140	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS12175	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EC609_RS12185	COG1333	cytochrome c biogenesis protein
EC609_RS12190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC609_RS12195	COG0019	diaminopimelate decarboxylase activity
EC609_RS12205	COG1965	Belongs to the frataxin family
EC609_RS12215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EC609_RS12220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EC609_RS12225	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EC609_RS12230	COG1473	amidohydrolase
EC609_RS12240	COG0583	DNA-binding transcription factor activity
EC609_RS12245	COG0625	glutathione transferase activity
EC609_RS12255	COG2814	Major facilitator Superfamily
EC609_RS12285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EC609_RS12320	COG2186	Transcriptional regulator
EC609_RS12345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC609_RS12355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC609_RS12395	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EC609_RS12400	COG3568	Endonuclease Exonuclease Phosphatase
EC609_RS12410	COG0697	spore germination
EC609_RS12415	COG2814	Major facilitator Superfamily
EC609_RS12430	COG0166	Belongs to the GPI family
EC609_RS12435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC609_RS12440	COG0859	PFAM glycosyl transferase family 9
EC609_RS12450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EC609_RS12460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EC609_RS12485	COG1686	Belongs to the peptidase S11 family
EC609_RS12500	COG0321	lipoyl(octanoyl) transferase activity
EC609_RS12515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EC609_RS12520	COG2076	Multidrug Resistance protein
EC609_RS12530	COG1216	Glycosyl transferase, family 2
EC609_RS12555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC609_RS12560	COG1216	Glycosyl transferase, family 2
EC609_RS12560	COG0438	transferase activity, transferring glycosyl groups
EC609_RS12580	COG3754	Rhamnan synthesis protein F
EC609_RS12610	COG2096	Adenosyltransferase
EC609_RS12620	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EC609_RS12625	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EC609_RS12635	COG0523	cobalamin synthesis protein
EC609_RS12640	COG0735	belongs to the Fur family
EC609_RS12665	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EC609_RS12670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EC609_RS12680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EC609_RS12685	COG1560	Kdo2-lipid A biosynthetic process
EC609_RS12695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EC609_RS12745	COG0477	Major facilitator Superfamily
EC609_RS12755	COG0583	DNA-binding transcription factor activity
EC609_RS12760	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS12765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EC609_RS12770	COG0066	3-isopropylmalate dehydratase activity
EC609_RS12775	COG0596	Alpha beta hydrolase
EC609_RS12785	COG0438	transferase activity, transferring glycosyl groups
EC609_RS12790	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EC609_RS12795	COG1950	PFAM Membrane protein of
EC609_RS12815	COG1305	Transglutaminase-like
EC609_RS12825	COG2308	Evidence 4 Homologs of previously reported genes of
EC609_RS12830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EC609_RS12870	COG0513	Belongs to the DEAD box helicase family
EC609_RS12875	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EC609_RS12885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EC609_RS12890	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS12895	COG3189	MarR family transcriptional regulator
EC609_RS12925	COG0640	Transcriptional regulator
EC609_RS12945	COG0730	response to heat
EC609_RS12990	COG1846	Transcriptional regulator
EC609_RS12995	COG1764	response to oxidative stress
EC609_RS13020	COG0583	DNA-binding transcription factor activity
EC609_RS13035	COG0583	DNA-binding transcription factor activity
EC609_RS13045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EC609_RS13050	COG1280	lysine exporter protein (LysE YggA)
EC609_RS13060	COG0708	Exodeoxyribonuclease III
EC609_RS13065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EC609_RS13080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EC609_RS13090	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EC609_RS13095	COG1077	Cell shape determining protein MreB Mrl
EC609_RS13110	COG0768	penicillin binding
EC609_RS13115	COG0772	Belongs to the SEDS family
EC609_RS13120	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EC609_RS13125	COG0471	metal ion transport
EC609_RS13130	COG1309	transcriptional regulator
EC609_RS13140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EC609_RS13155	COG2823	Periplasmic or secreted lipoprotein
EC609_RS13160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EC609_RS13175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC609_RS13200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC609_RS13205	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EC609_RS13215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EC609_RS13220	COG1137	ATPase activity
EC609_RS13235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EC609_RS13245	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EC609_RS13255	COG1271	oxidase subunit
EC609_RS13260	COG1294	oxidase, subunit
EC609_RS13270	COG4988	ABC transporter
EC609_RS13275	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EC609_RS13295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC609_RS13300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EC609_RS13320	COG0071	Belongs to the small heat shock protein (HSP20) family
EC609_RS13330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EC609_RS13335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC609_RS13340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS13355	COG0758	DNA mediated transformation
EC609_RS13360	COG0242	peptide deformylase activity
EC609_RS13365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EC609_RS13380	COG0546	phosphoglycolate phosphatase activity
EC609_RS13400	COG1733	regulation of RNA biosynthetic process
EC609_RS13410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EC609_RS13425	COG0840	transmembrane signaling receptor activity
EC609_RS13450	COG1280	lysine exporter protein (LysE YggA)
EC609_RS13455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EC609_RS13465	COG5000	phosphorelay sensor kinase activity
EC609_RS13470	COG2204	response regulator
EC609_RS13475	COG0569	domain protein
EC609_RS13480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EC609_RS13485	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EC609_RS13490	COG2226	methyltransferase
EC609_RS13500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EC609_RS13510	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EC609_RS13515	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EC609_RS13520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EC609_RS13525	COG1054	Belongs to the UPF0176 family
EC609_RS13530	COG0588	phosphoglycerate mutase activity
EC609_RS13535	COG4942	peptidase
EC609_RS13540	COG0793	Belongs to the peptidase S41A family
EC609_RS13545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EC609_RS13570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EC609_RS13585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EC609_RS13590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EC609_RS13595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EC609_RS13600	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EC609_RS13605	COG0142	geranyltranstransferase activity
EC609_RS13615	COG2814	Major facilitator Superfamily
EC609_RS13620	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC609_RS13630	COG2188	Transcriptional regulator
EC609_RS13635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS13640	COG1024	Enoyl-CoA hydratase
EC609_RS13645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EC609_RS13675	COG1960	acyl-CoA dehydrogenase activity
EC609_RS13685	COG0583	DNA-binding transcription factor activity
EC609_RS13690	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS13695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS13710	COG4585	Histidine kinase
EC609_RS13730	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS13740	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EC609_RS13745	COG1802	Transcriptional regulator
EC609_RS13750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EC609_RS13755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EC609_RS13760	COG1335	isochorismatase
EC609_RS13765	COG0523	cobalamin synthesis protein
EC609_RS13780	COG2188	Transcriptional regulator
EC609_RS13805	COG0683	leucine binding
EC609_RS13810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC609_RS13815	COG2084	Dehydrogenase
EC609_RS13825	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EC609_RS13845	COG0235	Class ii aldolase
EC609_RS13850	COG2271	Major facilitator Superfamily
EC609_RS13855	COG3622	Belongs to the hyi family
EC609_RS13860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC609_RS13865	COG2084	Dehydrogenase
EC609_RS13870	COG3395	kinase activity
EC609_RS13875	COG2186	Transcriptional regulator
EC609_RS13880	COG0583	DNA-binding transcription factor activity
EC609_RS13900	COG3842	ATPase activity
EC609_RS13910	COG0402	S-adenosylhomocysteine deaminase activity
EC609_RS13920	COG0523	cobalamin synthesis protein
EC609_RS13935	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS13940	COG0022	dehydrogenase e1 component
EC609_RS13955	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC609_RS13965	COG0583	DNA-binding transcription factor activity
EC609_RS13975	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EC609_RS14000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS14005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EC609_RS14010	COG3622	Belongs to the hyi family
EC609_RS14015	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS14025	COG5006	permease, DMT superfamily
EC609_RS14035	COG1522	sequence-specific DNA binding
EC609_RS14050	COG1473	amidohydrolase
EC609_RS14065	COG1595	DNA-templated transcription, initiation
EC609_RS14070	COG2217	Heavy metal translocating P-type atpase
EC609_RS14085	COG1132	(ABC) transporter
EC609_RS14095	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EC609_RS14095	COG3264	Mechanosensitive ion channel
EC609_RS14110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EC609_RS14120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EC609_RS14140	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS14170	COG0583	DNA-binding transcription factor activity
EC609_RS14185	COG0625	glutathione transferase activity
EC609_RS14200	COG0288	reversible hydration of carbon dioxide
EC609_RS14220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EC609_RS14230	COG4829	muconolactone delta-isomerase
EC609_RS14235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC609_RS14245	COG1414	Transcriptional regulator
EC609_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS14255	COG2031	fatty acid transporter
EC609_RS14260	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS14265	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EC609_RS14270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EC609_RS14285	COG0583	DNA-binding transcription factor activity
EC609_RS14290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EC609_RS14300	COG0129	dihydroxy-acid dehydratase activity
EC609_RS14305	COG0583	DNA-binding transcription factor activity
EC609_RS14310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC609_RS14315	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC609_RS14325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EC609_RS14330	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS14360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EC609_RS14370	COG2186	Transcriptional regulator
EC609_RS14380	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EC609_RS14395	COG2177	Part of the ABC transporter FtsEX involved in
EC609_RS14400	COG2884	Cell division ATP-binding protein ftsE
EC609_RS14405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS14410	COG4597	amino acid ABC transporter
EC609_RS14415	COG0765	amino acid transport
EC609_RS14420	COG1126	abc transporter atp-binding protein
EC609_RS14435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS14455	COG1414	Transcriptional regulator
EC609_RS14480	COG1129	ABC transporter
EC609_RS14485	COG4177	L-phenylalanine transmembrane transporter activity
EC609_RS14500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC609_RS14505	COG2081	HI0933 family
EC609_RS14515	COG0077	Prephenate dehydratase
EC609_RS14515	COG1605	Chorismate mutase
EC609_RS14565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC609_RS14570	COG0583	DNA-binding transcription factor activity
EC609_RS14575	COG0628	permease
EC609_RS14580	COG5285	phytanoyl-CoA dioxygenase
EC609_RS14595	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC609_RS14600	COG3842	ATPase activity
EC609_RS14610	COG0277	FAD linked oxidase domain protein
EC609_RS14625	COG0477	Major facilitator Superfamily
EC609_RS14640	COG1695	Transcriptional regulator
EC609_RS14675	COG2197	response regulator
EC609_RS14720	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS14730	COG3246	L-lysine catabolic process to acetate
EC609_RS14735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EC609_RS14740	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC609_RS14755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC609_RS14765	COG0583	DNA-binding transcription factor activity
EC609_RS14775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC609_RS14815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS14835	COG1595	DNA-templated transcription, initiation
EC609_RS14845	COG4774	siderophore transport
EC609_RS14855	COG4221	oxidoreductase activity
EC609_RS14905	COG2233	PERMEase
EC609_RS14910	COG0326	Molecular chaperone. Has ATPase activity
EC609_RS14920	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS14935	COG0604	alcohol dehydrogenase
EC609_RS14945	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS14970	COG2814	Major facilitator Superfamily
EC609_RS14975	COG2271	Major facilitator Superfamily
EC609_RS14980	COG4948	Mandelate Racemase Muconate Lactonizing
EC609_RS14985	COG0800	Aldolase
EC609_RS14990	COG3734	2-keto-3-deoxy-galactonokinase
EC609_RS14995	COG1414	Transcriptional regulator
EC609_RS15000	COG0625	glutathione transferase activity
EC609_RS15015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC609_RS15020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EC609_RS15025	COG1652	LysM domain
EC609_RS15045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EC609_RS15075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EC609_RS15080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EC609_RS15090	COG0387	Pfam Sodium calcium exchanger
EC609_RS15100	COG1595	DNA-templated transcription, initiation
EC609_RS15105	COG3712	iron ion homeostasis
EC609_RS15110	COG4774	siderophore transport
EC609_RS15115	COG1595	DNA-templated transcription, initiation
EC609_RS15120	COG4774	siderophore transport
EC609_RS15125	COG0583	DNA-binding transcription factor activity
EC609_RS15140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS15155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS15195	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS15200	COG0583	DNA-binding transcription factor activity
EC609_RS15205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC609_RS15210	COG2079	MmgE PrpD family protein
EC609_RS15220	COG0583	DNA-binding transcription factor activity
EC609_RS15235	COG1522	sequence-specific DNA binding
EC609_RS15245	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EC609_RS15255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS15260	COG0006	proline dipeptidase activity
EC609_RS15285	COG0688	phosphatidylethanolamine metabolic process
EC609_RS15320	COG0519	Catalyzes the synthesis of GMP from XMP
EC609_RS15320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EC609_RS15325	COG1802	Transcriptional regulator
EC609_RS15330	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS15340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC609_RS15350	COG0583	DNA-binding transcription factor activity
EC609_RS15355	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EC609_RS15370	COG3135	benzoate transporter
EC609_RS15375	COG0583	DNA-binding transcription factor activity
EC609_RS15380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EC609_RS15390	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EC609_RS15400	COG0625	glutathione transferase activity
EC609_RS15405	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS15415	COG2986	histidine ammonia-lyase
EC609_RS15420	COG0165	Argininosuccinate lyase
EC609_RS15440	COG0583	DNA-binding transcription factor activity
EC609_RS15470	COG3284	Transcriptional regulator
EC609_RS15475	COG0583	DNA-binding transcription factor activity
EC609_RS15485	COG0583	DNA-binding transcription factor activity
EC609_RS15495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EC609_RS15500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC609_RS15505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EC609_RS15510	COG1131	(ABC) transporter
EC609_RS15530	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC609_RS15540	COG1129	ABC transporter
EC609_RS15575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EC609_RS15590	COG0625	glutathione transferase activity
EC609_RS15600	COG1053	succinate dehydrogenase
EC609_RS15600	COG3976	FMN-binding domain protein
EC609_RS15620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC609_RS15630	COG1294	oxidase, subunit
EC609_RS15635	COG1271	oxidase subunit
EC609_RS15640	COG0697	spore germination
EC609_RS15655	COG0842	Transport permease protein
EC609_RS15660	COG1129	ABC transporter
EC609_RS15660	COG0842	Transport permease protein
EC609_RS15665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC609_RS15680	COG2200	EAL domain
EC609_RS15685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC609_RS15690	COG0745	RESPONSE REGULATOR receiver
EC609_RS15715	COG1054	Belongs to the UPF0176 family
EC609_RS15720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EC609_RS15720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EC609_RS15745	COG0717	Belongs to the dCTP deaminase family
EC609_RS15755	COG2199	diguanylate cyclase activity
EC609_RS15760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC609_RS15760	COG0456	acetyltransferase
EC609_RS15775	COG2081	HI0933 family
EC609_RS15790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EC609_RS15795	COG0509	glycine decarboxylation via glycine cleavage system
EC609_RS15800	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EC609_RS15800	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EC609_RS15815	COG0154	amidase activity
EC609_RS15820	COG4172	Belongs to the ABC transporter superfamily
EC609_RS15825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS15830	COG0601	transmembrane transport
EC609_RS15850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EC609_RS15855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC609_RS15880	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EC609_RS15890	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EC609_RS15905	COG0438	transferase activity, transferring glycosyl groups
EC609_RS15915	COG0438	transferase activity, transferring glycosyl groups
EC609_RS15920	COG0438	transferase activity, transferring glycosyl groups
EC609_RS15930	COG0166	Belongs to the GPI family
EC609_RS15945	COG0277	FAD linked oxidase domain protein
EC609_RS15950	COG0745	RESPONSE REGULATOR receiver
EC609_RS15955	COG2205	protein histidine kinase activity
EC609_RS15965	COG2186	Transcriptional regulator
EC609_RS15970	COG1368	sulfuric ester hydrolase activity
EC609_RS16015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EC609_RS16025	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EC609_RS16030	COG0840	transmembrane signaling receptor activity
EC609_RS16035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EC609_RS16055	COG0193	aminoacyl-tRNA hydrolase activity
EC609_RS16065	COG0012	GTP binding
EC609_RS16070	COG0582	viral genome integration into host DNA
EC609_RS16080	COG1111	helicase
EC609_RS16080	COG1205	dead DEAH box helicase
EC609_RS16085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EC609_RS16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC609_RS16135	COG0625	glutathione transferase activity
EC609_RS16155	COG2814	Major facilitator Superfamily
EC609_RS16170	COG3135	benzoate transporter
EC609_RS16175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC609_RS16180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EC609_RS16185	COG0742	ribosomal rna small subunit methyltransferase
EC609_RS16210	COG3639	organic phosphonate transmembrane transporter activity
EC609_RS16215	COG3639	organic phosphonate transmembrane transporter activity
EC609_RS16220	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EC609_RS16245	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EC609_RS16250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EC609_RS16265	COG1546	Belongs to the CinA family
EC609_RS16270	COG0284	orotidine-5'-phosphate decarboxylase activity
EC609_RS16275	COG1252	NADH dehydrogenase
EC609_RS16280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EC609_RS16285	COG0246	Mannitol dehydrogenase
EC609_RS16295	COG1917	Cupin 2, conserved barrel domain protein
EC609_RS16325	COG0459	protein refolding
EC609_RS16330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EC609_RS16350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EC609_RS16435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS16440	COG0601	transmembrane transport
EC609_RS16445	COG0747	negative chemotaxis
EC609_RS16465	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS16470	COG0583	DNA-binding transcription factor activity
EC609_RS16510	COG1053	succinate dehydrogenase
EC609_RS16530	COG1960	acyl-CoA dehydrogenase activity
EC609_RS16535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC609_RS16600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EC609_RS16605	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS16645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EC609_RS16655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS16665	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS16670	COG1024	Enoyl-CoA hydratase
EC609_RS16675	COG1024	Enoyl-CoA hydratase
EC609_RS16695	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS16735	COG0583	DNA-binding transcription factor activity
EC609_RS16755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EC609_RS16760	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EC609_RS16765	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EC609_RS16780	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS16785	COG3246	L-lysine catabolic process to acetate
EC609_RS16805	COG0456	acetyltransferase
EC609_RS16810	COG2814	Major facilitator Superfamily
EC609_RS16815	COG0583	DNA-binding transcription factor activity
EC609_RS16835	COG0583	DNA-binding transcription factor activity
EC609_RS16850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC609_RS16855	COG1902	pentaerythritol trinitrate reductase activity
EC609_RS16880	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC609_RS16910	COG0133	tryptophan synthase activity
EC609_RS16920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS16925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS16930	COG1126	abc transporter atp-binding protein
EC609_RS16935	COG0765	amino acid transport
EC609_RS16940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS16955	COG1024	Enoyl-CoA hydratase
EC609_RS16975	COG0444	Belongs to the ABC transporter superfamily
EC609_RS16985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS16995	COG1024	Enoyl-CoA hydratase
EC609_RS17025	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS17030	COG1802	Transcriptional regulator
EC609_RS17050	COG1280	lysine exporter protein (LysE YggA)
EC609_RS17065	COG0165	Argininosuccinate lyase
EC609_RS17075	COG1960	acyl-CoA dehydrogenase activity
EC609_RS17085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC609_RS17095	COG2030	dehydratase
EC609_RS17100	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS17105	COG0183	Belongs to the thiolase family
EC609_RS17115	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS17125	COG1024	Enoyl-CoA hydratase
EC609_RS17140	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS17155	COG2188	Transcriptional regulator
EC609_RS17160	COG0730	response to heat
EC609_RS17185	COG2837	iron assimilation
EC609_RS17190	COG1960	acyl-CoA dehydrogenase activity
EC609_RS17195	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS17200	COG1024	Enoyl-CoA hydratase
EC609_RS17205	COG1024	Enoyl-CoA hydratase
EC609_RS17225	COG4773	Receptor
EC609_RS17235	COG0667	Aldo Keto reductase
EC609_RS17240	COG3795	YCII-related domain
EC609_RS17260	COG2818	Glycosylase
EC609_RS17275	COG0590	tRNA wobble adenosine to inosine editing
EC609_RS17280	COG2814	Major facilitator Superfamily
EC609_RS17285	COG2207	Transcriptional regulator
EC609_RS17290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC609_RS17300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EC609_RS17305	COG1845	cytochrome c oxidase, subunit III
EC609_RS17310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EC609_RS17315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EC609_RS17320	COG0477	Major facilitator Superfamily
EC609_RS17325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS17330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EC609_RS17365	COG0583	DNA-binding transcription factor activity
EC609_RS17370	COG0861	Integral membrane protein TerC family
EC609_RS17375	COG4106	trans-aconitate 2-methyltransferase activity
EC609_RS17380	COG2207	Transcriptional regulator
EC609_RS17385	COG2807	transmembrane transport
EC609_RS17405	COG0330	HflC and HflK could
EC609_RS17415	COG1595	DNA-templated transcription, initiation
EC609_RS17420	COG3712	iron ion homeostasis
EC609_RS17430	COG2706	6-phosphogluconolactonase activity
EC609_RS17440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EC609_RS17450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC609_RS17455	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS17460	COG1285	pathogenesis
EC609_RS17465	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS17485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC609_RS17490	COG1396	sequence-specific DNA binding
EC609_RS17495	COG0456	acetyltransferase
EC609_RS17530	COG0697	spore germination
EC609_RS17555	COG0280	phosphate acetyltransferase
EC609_RS17555	COG0281	malic enzyme
EC609_RS17580	COG4772	TonB-dependent receptor
EC609_RS17595	COG1845	cytochrome c oxidase, subunit III
EC609_RS17600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EC609_RS17610	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EC609_RS17630	COG1999	signal sequence binding
EC609_RS17655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC609_RS17660	COG1120	ATPase activity
EC609_RS17675	COG4771	TonB-dependent receptor
EC609_RS17685	COG1126	abc transporter atp-binding protein
EC609_RS17690	COG0765	amino acid transport
EC609_RS17695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS17700	COG3191	aminopeptidase activity
EC609_RS17705	COG1272	protein, Hemolysin III
EC609_RS17710	COG1522	sequence-specific DNA binding
EC609_RS17725	COG2378	regulation of single-species biofilm formation
EC609_RS17740	COG1595	DNA-templated transcription, initiation
EC609_RS17745	COG3712	iron ion homeostasis
EC609_RS17755	COG3720	iron ion transport
EC609_RS17760	COG4558	Periplasmic binding protein
EC609_RS17765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC609_RS17775	COG1666	GTP binding
EC609_RS17785	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EC609_RS17805	COG0671	phosphoesterase, PA-phosphatase related
EC609_RS17885	COG0456	acetyltransferase
EC609_RS17890	COG1943	Transposase
EC609_RS17910	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS17950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EC609_RS17955	COG0583	DNA-binding transcription factor activity
EC609_RS17980	COG2223	nitrite transmembrane transporter activity
EC609_RS17995	COG3383	formate dehydrogenase (NAD+) activity
EC609_RS18005	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EC609_RS18015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EC609_RS18025	COG0303	'Molybdopterin
EC609_RS18030	COG0521	Mo-molybdopterin cofactor biosynthetic process
EC609_RS18045	COG0315	cyclic pyranopterin monophosphate synthase activity
EC609_RS18065	COG0678	peroxiredoxin activity
EC609_RS18075	COG0697	spore germination
EC609_RS18080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EC609_RS18120	COG0667	Aldo Keto reductase
EC609_RS18125	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EC609_RS18130	COG4535	Mg2 and Co2 transporter CorC
EC609_RS18135	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EC609_RS18140	COG1702	phosphate starvation-inducible protein PhoH
EC609_RS18145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EC609_RS18155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EC609_RS18165	COG0740	serine-type endopeptidase activity
EC609_RS18175	COG0640	Transcriptional regulator
EC609_RS18180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EC609_RS18190	COG1862	Preprotein translocase
EC609_RS18195	COG0343	queuine tRNA-ribosyltransferase activity
EC609_RS18200	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EC609_RS18220	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EC609_RS18235	COG4575	ribosome binding
EC609_RS18250	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EC609_RS18255	COG0741	lytic transglycosylase activity
EC609_RS18260	COG0436	Aminotransferase
EC609_RS18270	COG0281	malic enzyme
EC609_RS18270	COG0280	phosphate acetyltransferase
EC609_RS18280	COG2732	(Barnase) inhibitor
EC609_RS18285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EC609_RS18290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EC609_RS18295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EC609_RS18300	COG0126	phosphoglycerate kinase activity
EC609_RS18315	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EC609_RS18320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EC609_RS18340	COG0625	glutathione transferase activity
EC609_RS18380	COG0306	phosphate transporter
EC609_RS18390	COG0521	Mo-molybdopterin cofactor biosynthetic process
EC609_RS18400	COG0739	heme binding
EC609_RS18410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EC609_RS18430	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EC609_RS18435	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EC609_RS18440	COG3639	organic phosphonate transmembrane transporter activity
EC609_RS18455	COG0405	Gamma-glutamyltransferase
EC609_RS18460	COG0583	DNA-binding transcription factor activity
EC609_RS18465	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EC609_RS18470	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EC609_RS18475	COG3454	Phosphonate metabolism
EC609_RS18480	COG2188	Transcriptional regulator
EC609_RS18485	COG3624	Phosphonate C-P lyase system protein PhnG
EC609_RS18495	COG3626	phosphonate metabolism
EC609_RS18500	COG3627	carbon phosphorus lyase activity
EC609_RS18505	COG4107	phosphonate C-P lyase system protein PhnK
EC609_RS18510	COG4778	phosphonate C-P lyase system protein PhnL
EC609_RS18515	COG3454	Phosphonate metabolism
EC609_RS18555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EC609_RS18560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EC609_RS18565	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EC609_RS18570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EC609_RS18575	COG0009	L-threonylcarbamoyladenylate synthase
EC609_RS18580	COG1414	Transcriptional regulator
EC609_RS18585	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC609_RS18600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS18615	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS18630	COG0028	Belongs to the TPP enzyme family
EC609_RS18635	COG0583	DNA-binding transcription factor activity
EC609_RS18650	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC609_RS18655	COG2011	ABC-type metal ion transport system permease component
EC609_RS18660	COG3842	ATPase activity
EC609_RS18705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EC609_RS18725	COG2030	dehydratase
EC609_RS18740	COG1960	acyl-CoA dehydrogenase activity
EC609_RS18745	COG0028	Belongs to the TPP enzyme family
EC609_RS18750	COG0583	DNA-binding transcription factor activity
EC609_RS18755	COG4974	Belongs to the 'phage' integrase family
EC609_RS18780	COG1686	Belongs to the peptidase S11 family
EC609_RS18805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC609_RS18825	COG1074	ATP-dependent DNA helicase activity
EC609_RS18835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EC609_RS18850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS18855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EC609_RS18865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS18875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EC609_RS18880	COG0505	Belongs to the CarA family
EC609_RS18885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EC609_RS18890	COG4221	oxidoreductase activity
EC609_RS18895	COG0406	alpha-ribazole phosphatase activity
EC609_RS18905	COG3842	ATPase activity
EC609_RS18925	COG2233	PERMEase
EC609_RS18930	COG0840	transmembrane signaling receptor activity
EC609_RS18935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EC609_RS18940	COG1534	Rna-binding protein
EC609_RS18945	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EC609_RS18950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EC609_RS18960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EC609_RS18995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EC609_RS19010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EC609_RS19215	COG4386	tail sheath protein
EC609_RS19230	COG1196	nuclear chromosome segregation
EC609_RS19230	COG0739	heme binding
EC609_RS19230	COG0741	lytic transglycosylase activity
EC609_RS19325	COG0582	viral genome integration into host DNA
EC609_RS19345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EC609_RS19355	COG0583	DNA-binding transcription factor activity
EC609_RS19360	COG3485	protocatechuate 3,4-dioxygenase
EC609_RS19365	COG3485	protocatechuate 3,4-dioxygenase
EC609_RS19375	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC609_RS19485	COG4638	Rieske (2fe-2S)
EC609_RS19505	COG2963	transposase activity
EC609_RS19510	COG2801	Transposase and inactivated derivatives
EC609_RS19580	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS19600	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS19605	COG4948	Mandelate Racemase Muconate Lactonizing
EC609_RS19630	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS19685	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS19695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC609_RS19720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EC609_RS19740	COG2003	Belongs to the UPF0758 family
EC609_RS19785	COG3384	dioxygenase
EC609_RS19795	COG1802	Transcriptional regulator
EC609_RS19810	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC609_RS19815	COG1802	Transcriptional regulator
EC609_RS19820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EC609_RS19835	COG0840	transmembrane signaling receptor activity
EC609_RS19850	COG2841	Protein conserved in bacteria
EC609_RS19860	COG1335	isochorismatase
EC609_RS19865	COG1335	isochorismatase
EC609_RS19880	COG2207	Transcriptional regulator
EC609_RS19885	COG0667	Aldo Keto reductase
EC609_RS19900	COG0500	methyltransferase
EC609_RS19905	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS19910	COG3321	synthase
EC609_RS19910	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS19910	COG0604	alcohol dehydrogenase
EC609_RS19925	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC609_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS19940	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS19945	COG3246	L-lysine catabolic process to acetate
EC609_RS19950	COG0371	Dehydrogenase
EC609_RS19955	COG1802	Transcriptional regulator
EC609_RS19960	COG3959	Transketolase, thiamine diphosphate binding domain
EC609_RS19965	COG3958	Transketolase
EC609_RS19970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EC609_RS19980	COG3938	Belongs to the proline racemase family
EC609_RS19985	COG1177	transmembrane transport
EC609_RS19990	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC609_RS19995	COG3842	ATPase activity
EC609_RS20000	COG1840	ABC-type Fe3 transport system, periplasmic component
EC609_RS20050	COG0583	DNA-binding transcription factor activity
EC609_RS20055	COG0427	acetyl-CoA hydrolase
EC609_RS20060	COG0583	DNA-binding transcription factor activity
EC609_RS20105	COG0583	DNA-binding transcription factor activity
EC609_RS20120	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS20130	COG0477	Major facilitator Superfamily
EC609_RS20140	COG0154	amidase activity
EC609_RS20155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EC609_RS20170	COG0495	leucyl-tRNA aminoacylation
EC609_RS20175	COG2814	Major facilitator Superfamily
EC609_RS20190	COG1686	Belongs to the peptidase S11 family
EC609_RS20225	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EC609_RS20230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EC609_RS20235	COG2814	Major facilitator Superfamily
EC609_RS20240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EC609_RS20250	COG4176	ABC-type proline glycine betaine transport system permease component
EC609_RS20260	COG1942	4-Oxalocrotonate Tautomerase
EC609_RS20275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS20280	COG0583	DNA-binding transcription factor activity
EC609_RS20290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS20310	COG2030	dehydratase
EC609_RS20325	COG1960	acyl-CoA dehydrogenase activity
EC609_RS20330	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS20335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC609_RS20350	COG0439	Biotin carboxylase
EC609_RS20385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS20390	COG0601	transmembrane transport
EC609_RS20400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EC609_RS20410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EC609_RS20415	COG0436	Aminotransferase
EC609_RS20425	COG0330	HflC and HflK could
EC609_RS20445	COG1024	Enoyl-CoA hydratase
EC609_RS20450	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS20455	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS20460	COG0583	DNA-binding transcription factor activity
EC609_RS20465	COG1960	acyl-CoA dehydrogenase activity
EC609_RS20475	COG0183	Belongs to the thiolase family
EC609_RS20480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS20485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EC609_RS20490	COG3608	succinylglutamate desuccinylase aspartoacylase
EC609_RS20500	COG2814	Major facilitator Superfamily
EC609_RS20510	COG0633	Ferredoxin
EC609_RS20580	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS20595	COG1396	sequence-specific DNA binding
EC609_RS20615	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS20635	COG0765	amino acid transport
EC609_RS20640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS20670	COG0625	glutathione transferase activity
EC609_RS20675	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS20685	COG2186	Transcriptional regulator
EC609_RS20695	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EC609_RS20710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS20760	COG2323	membrane
EC609_RS20810	COG5265	(ABC) transporter
EC609_RS20820	COG0297	glycogen (starch) synthase activity
EC609_RS20825	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS20830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EC609_RS20840	COG2192	nodulation
EC609_RS20875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EC609_RS20890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EC609_RS20890	COG2010	Cytochrome c
EC609_RS20895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EC609_RS20915	COG0166	Belongs to the GPI family
EC609_RS20925	COG0668	transmembrane transport
EC609_RS20945	COG1546	Belongs to the CinA family
EC609_RS20945	COG1058	Belongs to the CinA family
EC609_RS20960	COG0247	lactate metabolic process
EC609_RS20980	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS20990	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS21035	COG1802	Transcriptional regulator
EC609_RS21055	COG2084	Dehydrogenase
EC609_RS21065	COG0183	Belongs to the thiolase family
EC609_RS21075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC609_RS21080	COG1960	acyl-CoA dehydrogenase activity
EC609_RS21085	COG1024	Enoyl-CoA hydratase
EC609_RS21085	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS21110	COG1024	Enoyl-CoA hydratase
EC609_RS21135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC609_RS21150	COG0784	Response regulator, receiver
EC609_RS21150	COG4191	Histidine kinase
EC609_RS21175	COG0583	DNA-binding transcription factor activity
EC609_RS21185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS21205	COG2084	Dehydrogenase
EC609_RS21210	COG1304	FMN binding
EC609_RS21220	COG2205	protein histidine kinase activity
EC609_RS21220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS21225	COG3706	GGDEF domain
EC609_RS21225	COG4251	negative regulation of phosphorylation
EC609_RS21225	COG2203	Gaf domain
EC609_RS21225	COG5001	Diguanylate cyclase
EC609_RS21250	COG2197	response regulator
EC609_RS21255	COG0784	Response regulator, receiver
EC609_RS21255	COG2205	protein histidine kinase activity
EC609_RS21280	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS21290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EC609_RS21315	COG0583	DNA-binding transcription factor activity
EC609_RS21330	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EC609_RS21340	COG2808	Putative FMN-binding domain
EC609_RS21370	COG2321	neutral zinc metallopeptidase
EC609_RS21375	COG0009	L-threonylcarbamoyladenylate synthase
EC609_RS21380	COG1994	Peptidase M50
EC609_RS21385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC609_RS21400	COG2850	peptidyl-arginine hydroxylation
EC609_RS21405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EC609_RS21420	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS21425	COG0583	DNA-binding transcription factor activity
EC609_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS21465	COG3360	Dodecin
EC609_RS21485	COG1802	Transcriptional regulator
EC609_RS21510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EC609_RS21530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC609_RS21570	COG0668	transmembrane transport
EC609_RS21590	COG0483	inositol monophosphate 1-phosphatase activity
EC609_RS21605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EC609_RS21620	COG4263	nitrous-oxide reductase activity
EC609_RS21640	COG1968	undecaprenyl-diphosphatase activity
EC609_RS21645	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC609_RS21660	COG0215	cysteine-tRNA ligase activity
EC609_RS21670	COG0825	malonyl-CoA metabolic process
EC609_RS21680	COG0527	aspartate kinase activity
EC609_RS21690	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EC609_RS21715	COG1414	Transcriptional regulator
EC609_RS21760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EC609_RS21775	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS21790	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EC609_RS21795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC609_RS21800	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS21810	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC609_RS21815	COG2186	Transcriptional regulator
EC609_RS21825	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EC609_RS21830	COG3395	kinase activity
EC609_RS21840	COG4774	siderophore transport
EC609_RS21845	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS21860	COG0183	Belongs to the thiolase family
EC609_RS21885	COG1960	acyl-CoA dehydrogenase activity
EC609_RS21900	COG2197	response regulator
EC609_RS21905	COG2197	response regulator
EC609_RS21915	COG0297	glycogen (starch) synthase activity
EC609_RS21920	COG0110	maltose O-acetyltransferase activity
EC609_RS21925	COG0463	Glycosyl transferase, family 2
EC609_RS21955	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EC609_RS21970	COG1051	belongs to the nudix hydrolase family
EC609_RS21995	COG0166	Belongs to the GPI family
EC609_RS22000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EC609_RS22005	COG1045	serine acetyltransferase
EC609_RS22010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EC609_RS22025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EC609_RS22045	COG0598	Magnesium transport protein CorA
EC609_RS22065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS22070	COG4172	Belongs to the ABC transporter superfamily
EC609_RS22080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EC609_RS22095	COG3384	dioxygenase
EC609_RS22100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EC609_RS22105	COG1802	Transcriptional regulator
EC609_RS22155	COG3842	ATPase activity
EC609_RS22165	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS22170	COG0395	ABC-type sugar transport system, permease component
EC609_RS22185	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS22190	COG0583	DNA-binding transcription factor activity
EC609_RS22220	COG0517	IMP dehydrogenase activity
EC609_RS22220	COG0516	GMP reductase activity
EC609_RS22260	COG4948	Mandelate Racemase Muconate Lactonizing
EC609_RS22280	COG1960	acyl-CoA dehydrogenase activity
EC609_RS22285	COG1024	Enoyl-CoA hydratase
EC609_RS22295	COG2197	response regulator
EC609_RS22310	COG0517	IMP dehydrogenase activity
EC609_RS22310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EC609_RS22310	COG0617	tRNA 3'-terminal CCA addition
EC609_RS22315	COG0589	response to stress
EC609_RS22320	COG0589	response to stress
EC609_RS22325	COG0071	Belongs to the small heat shock protein (HSP20) family
EC609_RS22355	COG1024	Enoyl-CoA hydratase
EC609_RS22370	COG1960	acyl-CoA dehydrogenase activity
EC609_RS22385	COG1802	Transcriptional regulator
EC609_RS22395	COG1024	Enoyl-CoA hydratase
EC609_RS22400	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS22410	COG0667	Aldo Keto reductase
EC609_RS22420	COG4120	Belongs to the binding-protein-dependent transport system permease family
EC609_RS22425	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EC609_RS22430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS22440	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EC609_RS22460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EC609_RS22465	COG0725	ABC transporter, periplasmic molybdate-binding protein
EC609_RS22470	COG4149	molybdate abc transporter
EC609_RS22505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC609_RS22515	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EC609_RS22520	COG0736	holo-[acyl-carrier-protein] synthase activity
EC609_RS22535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EC609_RS22545	COG1858	cytochrome C peroxidase
EC609_RS22550	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EC609_RS22550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EC609_RS22555	COG2224	Isocitrate lyase
EC609_RS22565	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS22570	COG2301	Belongs to the HpcH HpaI aldolase family
EC609_RS22600	COG0156	8-amino-7-oxononanoate synthase activity
EC609_RS22620	COG3278	Belongs to the heme-copper respiratory oxidase family
EC609_RS22640	COG0348	domain, Protein
EC609_RS22655	COG2824	Alkylphosphonate utilization operon protein PhnA
EC609_RS22665	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS22685	COG1131	(ABC) transporter
EC609_RS22690	COG0842	Transport permease protein
EC609_RS22715	COG1272	protein, Hemolysin III
EC609_RS22755	COG0251	oxidation-reduction process
EC609_RS22765	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EC609_RS22775	COG0583	DNA-binding transcription factor activity
EC609_RS22785	COG0861	Integral membrane protein TerC family
EC609_RS22805	COG1566	PFAM secretion protein HlyD family protein
EC609_RS22820	COG0583	DNA-binding transcription factor activity
EC609_RS22835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS22850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EC609_RS22855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EC609_RS22865	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC609_RS22870	COG0596	Alpha beta hydrolase
EC609_RS22875	COG1228	amidohydrolase
EC609_RS22900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EC609_RS22905	COG2011	ABC-type metal ion transport system permease component
EC609_RS22940	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS22960	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
EC609_RS22970	COG1473	amidohydrolase
EC609_RS22975	COG0477	Major facilitator Superfamily
EC609_RS22995	COG2951	lytic endotransglycosylase activity
EC609_RS23000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EC609_RS23015	COG0519	Catalyzes the synthesis of GMP from XMP
EC609_RS23025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS23040	COG4172	Belongs to the ABC transporter superfamily
EC609_RS23055	COG3210	domain, Protein
EC609_RS23150	COG2801	Transposase and inactivated derivatives
EC609_RS23180	COG0443	Heat shock 70 kDa protein
EC609_RS23200	COG1522	sequence-specific DNA binding
EC609_RS23240	COG1846	Transcriptional regulator
EC609_RS23250	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EC609_RS23290	COG3530	Putative quorum-sensing-regulated virulence factor
EC609_RS23320	COG0443	Heat shock 70 kDa protein
EC609_RS23325	COG0494	nUDIX hydrolase
EC609_RS23355	COG0477	Major facilitator Superfamily
EC609_RS23365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC609_RS23375	COG0542	response to heat
EC609_RS23380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC609_RS23390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS23400	COG0747	negative chemotaxis
EC609_RS23405	COG0235	Class ii aldolase
EC609_RS23420	COG3485	protocatechuate 3,4-dioxygenase
EC609_RS23425	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS23460	COG5441	Belongs to the UPF0261 family
EC609_RS23465	COG5564	TIM-barrel signal transduction protein
EC609_RS23480	COG0583	DNA-binding transcription factor activity
EC609_RS23485	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EC609_RS23500	COG1477	protein flavinylation
EC609_RS23535	COG1562	ergosterol biosynthetic process
EC609_RS23545	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EC609_RS23550	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS23555	COG0583	DNA-binding transcription factor activity
EC609_RS23560	COG1942	4-Oxalocrotonate Tautomerase
EC609_RS23570	COG3971	2-oxopent-4-enoate hydratase activity
EC609_RS23580	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC609_RS23585	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS23590	COG3384	dioxygenase
EC609_RS23620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC609_RS23625	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS23630	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS23640	COG2186	Transcriptional regulator
EC609_RS23670	COG0583	DNA-binding transcription factor activity
EC609_RS23675	COG0268	Binds directly to 16S ribosomal RNA
EC609_RS23685	COG0728	peptidoglycan biosynthetic process
EC609_RS23695	COG0563	adenylate kinase activity
EC609_RS23700	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EC609_RS23705	COG2835	tetraacyldisaccharide 4'-kinase activity
EC609_RS23715	COG1663	tetraacyldisaccharide 4'-kinase activity
EC609_RS23725	COG0811	peptide transport
EC609_RS23735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EC609_RS23745	COG0038	chloride channel
EC609_RS23750	COG0183	Belongs to the thiolase family
EC609_RS23765	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EC609_RS23770	COG2373	Large extracellular alpha-helical protein
EC609_RS23775	COG4953	penicillin-binding protein 1C
EC609_RS23785	COG2995	paraquat-inducible protein a
EC609_RS23790	COG3008	intermembrane lipid transfer
EC609_RS23810	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC609_RS23830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS23835	COG1024	Enoyl-CoA hydratase
EC609_RS23845	COG1802	Transcriptional regulator
EC609_RS23850	COG2271	Major facilitator Superfamily
EC609_RS23870	COG0640	Transcriptional regulator
EC609_RS23880	COG1914	H( )-stimulated, divalent metal cation uptake system
EC609_RS23885	COG1764	response to oxidative stress
EC609_RS23895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS23900	COG0765	amino acid transport
EC609_RS23905	COG0765	amino acid transport
EC609_RS23910	COG1126	abc transporter atp-binding protein
EC609_RS23915	COG1902	pentaerythritol trinitrate reductase activity
EC609_RS23930	COG0583	DNA-binding transcription factor activity
EC609_RS23955	COG3121	Chaperone
EC609_RS23960	COG3188	usher protein
EC609_RS23970	COG3188	usher protein
EC609_RS23990	COG2831	hemolysin activation secretion protein
EC609_RS23995	COG2197	response regulator
EC609_RS24025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EC609_RS24030	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EC609_RS24035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EC609_RS24050	COG0196	riboflavin kinase activity
EC609_RS24055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EC609_RS24065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EC609_RS24065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EC609_RS24080	COG0210	DNA helicase
EC609_RS24090	COG0488	(ABC) transporter
EC609_RS24095	COG2890	protein-(glutamine-N5) methyltransferase activity
EC609_RS24105	COG2171	N-acyltransferase activity
EC609_RS24110	COG0436	Aminotransferase
EC609_RS24150	COG2271	Major facilitator Superfamily
EC609_RS24155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EC609_RS24160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EC609_RS24165	COG0277	FAD linked oxidase domain protein
EC609_RS24185	COG3038	cytochrome b561
EC609_RS24190	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EC609_RS24200	COG3008	intermembrane lipid transfer
EC609_RS24235	COG0583	DNA-binding transcription factor activity
EC609_RS24245	COG0251	oxidation-reduction process
EC609_RS24275	COG1278	Cold shock
EC609_RS24285	COG1278	Cold shock
EC609_RS24300	COG0544	peptidyl-prolyl cis-trans isomerase activity
EC609_RS24305	COG0740	serine-type endopeptidase activity
EC609_RS24310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EC609_RS24320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EC609_RS24325	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS24330	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS24350	COG0556	nucleotide-excision repair
EC609_RS24355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EC609_RS24365	COG1104	cysteine desulfurase activity
EC609_RS24370	COG0822	iron-sulfur transferase activity
EC609_RS24375	COG0316	Belongs to the HesB IscA family
EC609_RS24380	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EC609_RS24385	COG0443	Heat shock 70 kDa protein
EC609_RS24395	COG2975	iron-sulfur cluster assembly
EC609_RS24400	COG1803	Methylglyoxal synthase
EC609_RS24425	COG1024	Enoyl-CoA hydratase
EC609_RS24460	COG0183	Belongs to the thiolase family
EC609_RS24465	COG1309	transcriptional regulator
EC609_RS24490	COG1454	alcohol dehydrogenase
EC609_RS24495	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS24530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EC609_RS24535	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS24550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EC609_RS24565	COG1136	(ABC) transporter
EC609_RS24570	COG0084	hydrolase, TatD family'
EC609_RS24575	COG4771	TonB-dependent receptor
EC609_RS24580	COG2205	protein histidine kinase activity
EC609_RS24585	COG0745	RESPONSE REGULATOR receiver
EC609_RS24595	COG4607	ABC-type enterochelin transport system periplasmic component
EC609_RS24600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC609_RS24605	COG4605	iron ion homeostasis
EC609_RS24610	COG4604	ABC transporter, ATP-binding protein
EC609_RS24625	COG0583	DNA-binding transcription factor activity
EC609_RS24635	COG1960	acyl-CoA dehydrogenase activity
EC609_RS24640	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS24650	COG0028	Belongs to the TPP enzyme family
EC609_RS24670	COG0625	glutathione transferase activity
EC609_RS24675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS24710	COG1454	alcohol dehydrogenase
EC609_RS24715	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EC609_RS24730	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS24740	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS24760	COG1850	ribulose-bisphosphate carboxylase activity
EC609_RS24770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EC609_RS24775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EC609_RS24795	COG3707	response regulator
EC609_RS24815	COG0515	serine threonine protein kinase
EC609_RS24815	COG2815	serine threonine protein kinase
EC609_RS24820	COG2116	formate transmembrane transporter activity
EC609_RS24825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EC609_RS24825	COG2146	nitrite reductase [NAD(P)H] activity
EC609_RS24835	COG0583	DNA-binding transcription factor activity
EC609_RS24845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EC609_RS24855	COG0613	PHP domain protein
EC609_RS24865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EC609_RS24880	COG0047	phosphoribosylformylglycinamidine synthase activity
EC609_RS24880	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EC609_RS24890	COG0583	DNA-binding transcription factor activity
EC609_RS24910	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS24925	COG3712	iron ion homeostasis
EC609_RS24955	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS25005	COG0583	DNA-binding transcription factor activity
EC609_RS25015	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS25025	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS25030	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
EC609_RS25040	COG1335	isochorismatase
EC609_RS25075	COG3468	outer membrane autotransporter barrel domain protein
EC609_RS25090	COG2084	Dehydrogenase
EC609_RS25105	COG2271	Major facilitator Superfamily
EC609_RS25110	COG0583	DNA-binding transcription factor activity
EC609_RS25115	COG4692	amylo-alpha-1,6-glucosidase activity
EC609_RS25150	COG3706	GGDEF domain
EC609_RS25160	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EC609_RS25200	COG2963	transposase activity
EC609_RS25230	COG1396	sequence-specific DNA binding
EC609_RS25265	COG0747	negative chemotaxis
EC609_RS25275	COG0444	Belongs to the ABC transporter superfamily
EC609_RS25280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS25285	COG0601	transmembrane transport
EC609_RS25290	COG2072	flavoprotein involved in K transport
EC609_RS25355	COG0519	Catalyzes the synthesis of GMP from XMP
EC609_RS25355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EC609_RS25360	COG0582	viral genome integration into host DNA
EC609_RS25465	COG1960	acyl-CoA dehydrogenase activity
EC609_RS25480	COG0583	DNA-binding transcription factor activity
EC609_RS25490	COG3384	dioxygenase
EC609_RS25500	COG0583	DNA-binding transcription factor activity
EC609_RS25505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS25510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EC609_RS25525	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EC609_RS25615	COG2003	Belongs to the UPF0758 family
EC609_RS25640	COG1475	DNA binding
EC609_RS25660	COG1695	Transcriptional regulator
EC609_RS25670	COG0798	PFAM Bile acid sodium symporter
EC609_RS25685	COG0640	Transcriptional regulator
EC609_RS25690	COG5489	Protein of unknown function (DUF736)
EC609_RS25735	COG1192	Involved in chromosome partitioning
EC609_RS25750	COG4959	Type IV secretory pathway protease TraF
EC609_RS25775	COG0642	Histidine kinase
EC609_RS25785	COG3038	cytochrome b561
EC609_RS25810	COG0583	DNA-binding transcription factor activity
EC609_RS25830	COG4962	Type ii secretion system protein e
EC609_RS25835	COG3838	Conjugal transfer protein Trbc
EC609_RS25845	COG3451	type IV secretory pathway VirB4
EC609_RS25860	COG3846	protein secretion by the type IV secretion system
EC609_RS25890	COG1278	Cold shock
EC609_RS25945	COG2186	Transcriptional regulator
EC609_RS25965	COG0583	DNA-binding transcription factor activity
EC609_RS25990	COG3842	ATPase activity
EC609_RS25995	COG1178	ABC-type Fe3 transport system permease component
EC609_RS26010	COG0753	catalase activity
EC609_RS26020	COG3550	peptidyl-serine autophosphorylation
EC609_RS26035	COG1063	alcohol dehydrogenase
EC609_RS26040	COG3284	Transcriptional regulator
EC609_RS26045	COG4647	ligase activity
EC609_RS26050	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
EC609_RS26055	COG0145	ligase activity
EC609_RS26080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS26125	COG1199	ATP-dependent helicase activity
EC609_RS26135	COG0154	amidase activity
EC609_RS26140	COG0840	transmembrane signaling receptor activity
EC609_RS26145	COG0835	chemotaxis
EC609_RS26165	COG2201	protein-glutamate methylesterase activity
EC609_RS26170	COG3706	GGDEF domain
EC609_RS26170	COG2203	Gaf domain
EC609_RS26170	COG5001	Diguanylate cyclase
EC609_RS26170	COG4251	negative regulation of phosphorylation
EC609_RS26175	COG1522	sequence-specific DNA binding
EC609_RS26200	COG0583	DNA-binding transcription factor activity
EC609_RS26225	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS26230	COG1960	acyl-CoA dehydrogenase activity
EC609_RS26235	COG1960	acyl-CoA dehydrogenase activity
EC609_RS26240	COG0183	Belongs to the thiolase family
EC609_RS26245	COG1024	Enoyl-CoA hydratase
EC609_RS26245	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS26250	COG0583	DNA-binding transcription factor activity
EC609_RS26260	COG2733	membrane
EC609_RS26265	COG2032	superoxide dismutase activity
EC609_RS26295	COG2885	chlorophyll binding
EC609_RS26355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EC609_RS26380	COG1846	Transcriptional regulator
EC609_RS26395	COG0583	DNA-binding transcription factor activity
EC609_RS26405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC609_RS26410	COG0697	spore germination
EC609_RS26420	COG4941	Belongs to the sigma-70 factor family
EC609_RS26430	COG3795	YCII-related domain
EC609_RS26435	COG3795	YCII-related domain
EC609_RS26450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EC609_RS26495	COG2885	chlorophyll binding
EC609_RS26495	COG3047	cAMP biosynthetic process
EC609_RS26515	COG2207	Transcriptional regulator
EC609_RS26525	COG1683	Conserved Protein
EC609_RS26550	COG1309	transcriptional regulator
EC609_RS26560	COG3655	Transcriptional regulator
EC609_RS26575	COG4608	Belongs to the ABC transporter superfamily
EC609_RS26580	COG0444	Belongs to the ABC transporter superfamily
EC609_RS26585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS26590	COG0601	transmembrane transport
EC609_RS26600	COG1802	Transcriptional regulator
EC609_RS26605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EC609_RS26615	COG0667	Aldo Keto reductase
EC609_RS26620	COG0477	Major facilitator Superfamily
EC609_RS26630	COG1414	Transcriptional regulator
EC609_RS26635	COG1802	Transcriptional regulator
EC609_RS26645	COG1473	amidohydrolase
EC609_RS26660	COG1595	DNA-templated transcription, initiation
EC609_RS26670	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EC609_RS26750	COG3045	CreA protein
EC609_RS26760	COG2264	protein methyltransferase activity
EC609_RS26765	COG4771	TonB-dependent receptor
EC609_RS26800	COG0583	DNA-binding transcription factor activity
EC609_RS26805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC609_RS26815	COG1959	2 iron, 2 sulfur cluster binding
EC609_RS26830	COG4774	siderophore transport
EC609_RS26835	COG4774	siderophore transport
EC609_RS26875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC609_RS26885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS26890	COG0765	amino acid transport
EC609_RS26895	COG0765	amino acid transport
EC609_RS26900	COG1126	abc transporter atp-binding protein
EC609_RS26915	COG0494	nUDIX hydrolase
EC609_RS26920	COG0587	DNA-directed DNA polymerase activity
EC609_RS26940	COG0833	amino acid
EC609_RS26945	COG0400	carboxylic ester hydrolase activity
EC609_RS26955	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS26960	COG0251	oxidation-reduction process
EC609_RS26965	COG0251	oxidation-reduction process
EC609_RS26975	COG0154	amidase activity
EC609_RS26985	COG0411	ABC transporter
EC609_RS27010	COG1566	PFAM secretion protein HlyD family protein
EC609_RS27030	COG0720	synthase
EC609_RS27035	COG0602	queuosine metabolic process
EC609_RS27050	COG0583	DNA-binding transcription factor activity
EC609_RS27055	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS27060	COG0154	amidase activity
EC609_RS27115	COG0842	Transport permease protein
EC609_RS27120	COG1131	(ABC) transporter
EC609_RS27130	COG1309	transcriptional regulator
EC609_RS27135	COG2130	NADP-dependent
EC609_RS27160	COG3842	ATPase activity
EC609_RS27165	COG3842	ATPase activity
EC609_RS27175	COG0395	ABC-type sugar transport system, permease component
EC609_RS27190	COG3634	alkyl hydroperoxide reductase activity
EC609_RS27200	COG3387	PFAM Glycoside hydrolase 15-related
EC609_RS27235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS27240	COG0420	3'-5' exonuclease activity
EC609_RS27270	COG2111	Na H antiporter
EC609_RS27270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EC609_RS27275	COG1006	Multisubunit Na H antiporter MnhC subunit
EC609_RS27280	COG0651	ATP synthesis coupled electron transport
EC609_RS27285	COG1863	multisubunit Na H antiporter MnhE subunit
EC609_RS27290	COG2212	antiporter activity
EC609_RS27310	COG0590	tRNA wobble adenosine to inosine editing
EC609_RS27315	COG1619	proteins homologs of microcin C7 resistance protein MccF
EC609_RS27320	COG0583	DNA-binding transcription factor activity
EC609_RS27335	COG0604	alcohol dehydrogenase
EC609_RS27340	COG0488	(ABC) transporter
EC609_RS27375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC609_RS27380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC609_RS27385	COG2252	PERMEase
EC609_RS27390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EC609_RS27395	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EC609_RS27405	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EC609_RS27430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EC609_RS27435	COG0789	Transcriptional regulator
EC609_RS27445	COG0678	peroxiredoxin activity
EC609_RS27445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EC609_RS27455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EC609_RS27460	COG0584	glycerophosphoryl diester phosphodiesterase
EC609_RS27470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC609_RS27480	COG4181	ATPase activity
EC609_RS27490	COG1178	ABC-type Fe3 transport system permease component
EC609_RS27495	COG3842	ATPase activity
EC609_RS27500	COG0583	DNA-binding transcription factor activity
EC609_RS27505	COG0560	Phosphoserine phosphatase
EC609_RS27515	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EC609_RS27525	COG0583	DNA-binding transcription factor activity
EC609_RS27555	COG0583	DNA-binding transcription factor activity
EC609_RS27560	COG4336	lyase activity
EC609_RS27590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC609_RS27630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS27635	COG0765	amino acid transport
EC609_RS27645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC609_RS27650	COG1758	RNA polymerase activity
EC609_RS27655	COG0194	GDP metabolic process
EC609_RS27660	COG3258	Cytochrome c
EC609_RS27665	COG2863	cytochrome
EC609_RS27670	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS27675	COG0791	NLP P60 protein
EC609_RS27680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EC609_RS27685	COG0833	amino acid
EC609_RS27695	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
EC609_RS27700	COG1561	YicC-like family, N-terminal region
EC609_RS27705	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EC609_RS27710	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS27735	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS27745	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS27770	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EC609_RS27780	COG0174	glutamine synthetase
EC609_RS27790	COG2204	response regulator
EC609_RS27795	COG0583	DNA-binding transcription factor activity
EC609_RS27800	COG1741	Belongs to the pirin family
EC609_RS27805	COG1741	Belongs to the pirin family
EC609_RS27810	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS27815	COG3842	ATPase activity
EC609_RS27825	COG1840	ABC-type Fe3 transport system, periplasmic component
EC609_RS27840	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS27845	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS27850	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS27885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EC609_RS27890	COG0583	DNA-binding transcription factor activity
EC609_RS27895	COG0783	Belongs to the Dps family
EC609_RS27910	COG0463	Glycosyl transferase, family 2
EC609_RS27930	COG0438	transferase activity, transferring glycosyl groups
EC609_RS27955	COG0300	oxidoreductase activity
EC609_RS27965	COG0156	8-amino-7-oxononanoate synthase activity
EC609_RS27970	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS27970	COG3321	synthase
EC609_RS27970	COG0604	alcohol dehydrogenase
EC609_RS27985	COG0745	RESPONSE REGULATOR receiver
EC609_RS27990	COG2205	protein histidine kinase activity
EC609_RS27995	COG3842	ATPase activity
EC609_RS28000	COG0395	ABC-type sugar transport system, permease component
EC609_RS28005	COG1175	transmembrane transport
EC609_RS28010	COG1653	transport
EC609_RS28020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EC609_RS28035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS28040	COG0583	DNA-binding transcription factor activity
EC609_RS28050	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC609_RS28070	COG1794	racemase activity, acting on amino acids and derivatives
EC609_RS28075	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EC609_RS28090	COG0625	glutathione transferase activity
EC609_RS28095	COG2133	pyrroloquinoline quinone binding
EC609_RS28105	COG0697	spore germination
EC609_RS28110	COG2363	Small membrane protein
EC609_RS28140	COG0010	Belongs to the arginase family
EC609_RS28145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EC609_RS28150	COG1464	Belongs to the NlpA lipoprotein family
EC609_RS28170	COG1408	metallophosphoesterase
EC609_RS28180	COG0688	phosphatidylethanolamine metabolic process
EC609_RS28195	COG0488	(ABC) transporter
EC609_RS28200	COG1686	Belongs to the peptidase S11 family
EC609_RS28225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS28230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EC609_RS28235	COG2203	Gaf domain
EC609_RS28235	COG2200	EAL domain
EC609_RS28235	COG2199	diguanylate cyclase activity
EC609_RS28240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC609_RS28255	COG2814	Major facilitator Superfamily
EC609_RS28275	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EC609_RS28280	COG2204	response regulator
EC609_RS28315	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS28325	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EC609_RS28360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC609_RS28375	COG5001	Diguanylate cyclase
EC609_RS28375	COG3300	MHYT domain
EC609_RS28385	COG1640	4-alpha-glucanotransferase
EC609_RS28390	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EC609_RS28400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EC609_RS28405	COG0366	Alpha amylase catalytic
EC609_RS28410	COG0366	Alpha amylase catalytic
EC609_RS28415	COG0297	glycogen (starch) synthase activity
EC609_RS28420	COG0028	Belongs to the TPP enzyme family
EC609_RS28440	COG0392	lysyltransferase activity
EC609_RS28445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC609_RS28450	COG3568	Endonuclease Exonuclease Phosphatase
EC609_RS28470	COG1253	flavin adenine dinucleotide binding
EC609_RS28480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EC609_RS28495	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC609_RS28505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EC609_RS28555	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EC609_RS28565	COG0628	permease
EC609_RS28585	COG1522	sequence-specific DNA binding
EC609_RS28600	COG1619	proteins homologs of microcin C7 resistance protein MccF
EC609_RS28615	COG0583	DNA-binding transcription factor activity
EC609_RS28730	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS28735	COG1024	Enoyl-CoA hydratase
EC609_RS28740	COG1414	Transcriptional regulator
EC609_RS28750	COG0625	glutathione transferase activity
EC609_RS28775	COG1937	Protein conserved in bacteria
EC609_RS28790	COG0698	ribose 5-phosphate isomerase
EC609_RS28795	COG0431	NADPH-dependent FMN reductase
EC609_RS28805	COG0798	PFAM Bile acid sodium symporter
EC609_RS28825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC609_RS28835	COG3284	Transcriptional regulator
EC609_RS28845	COG0583	DNA-binding transcription factor activity
EC609_RS28860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC609_RS28895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC609_RS28910	COG0277	FAD linked oxidase domain protein
EC609_RS28915	COG1414	Transcriptional regulator
EC609_RS28940	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS28945	COG0477	Major facilitator Superfamily
EC609_RS28955	COG0583	DNA-binding transcription factor activity
EC609_RS28960	COG2353	YceI-like domain
EC609_RS28965	COG1335	isochorismatase
EC609_RS29000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS29025	COG2271	Major facilitator Superfamily
EC609_RS29050	COG0747	negative chemotaxis
EC609_RS29060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS29065	COG0444	Belongs to the ABC transporter superfamily
EC609_RS29070	COG4608	Belongs to the ABC transporter superfamily
EC609_RS29080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EC609_RS29090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EC609_RS29090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EC609_RS29100	COG0028	Belongs to the TPP enzyme family
EC609_RS29110	COG1012	belongs to the aldehyde dehydrogenase family
EC609_RS29120	COG0235	Class ii aldolase
EC609_RS29130	COG0583	DNA-binding transcription factor activity
EC609_RS29140	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS29155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EC609_RS29175	COG0390	transport system, permease component
EC609_RS29180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EC609_RS29185	COG1126	abc transporter atp-binding protein
EC609_RS29190	COG0765	amino acid transport
EC609_RS29215	COG0765	amino acid transport
EC609_RS29220	COG0010	Belongs to the arginase family
EC609_RS29225	COG1126	abc transporter atp-binding protein
EC609_RS29235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EC609_RS29240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC609_RS29275	COG4566	intracellular signal transduction
EC609_RS29280	COG1960	acyl-CoA dehydrogenase activity
EC609_RS29285	COG1024	Enoyl-CoA hydratase
EC609_RS29290	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS29300	COG0583	DNA-binding transcription factor activity
EC609_RS29320	COG0583	DNA-binding transcription factor activity
EC609_RS29350	COG0765	amino acid transport
EC609_RS29380	COG1304	FMN binding
EC609_RS29395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC609_RS29400	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS29415	COG1764	response to oxidative stress
EC609_RS29420	COG0583	DNA-binding transcription factor activity
EC609_RS29430	COG1595	DNA-templated transcription, initiation
EC609_RS29440	COG4948	Mandelate Racemase Muconate Lactonizing
EC609_RS29455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC609_RS29475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS29480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EC609_RS29485	COG1116	anion transmembrane transporter activity
EC609_RS29515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EC609_RS29520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS29525	COG4597	amino acid ABC transporter
EC609_RS29530	COG3154	lipid carrier protein
EC609_RS29535	COG0826	peptidase U32
EC609_RS29540	COG0826	peptidase U32
EC609_RS29545	COG2197	response regulator
EC609_RS29550	COG1763	Mo-molybdopterin cofactor biosynthetic process
EC609_RS29555	COG0288	reversible hydration of carbon dioxide
EC609_RS29560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EC609_RS29565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC609_RS29570	COG2181	nitrate reductase activity
EC609_RS29575	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EC609_RS29580	COG1140	nitrate reductase beta subunit
EC609_RS29585	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EC609_RS29660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC609_RS29700	COG1328	CTP reductase activity
EC609_RS29715	COG2070	2-Nitropropane dioxygenase
EC609_RS29725	COG0574	Belongs to the PEP-utilizing enzyme family
EC609_RS29725	COG3848	Pyruvate phosphate dikinase
EC609_RS29730	COG2205	protein histidine kinase activity
EC609_RS29735	COG0745	RESPONSE REGULATOR receiver
EC609_RS29740	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EC609_RS29745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EC609_RS29760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EC609_RS29775	COG0410	ABC transporter
EC609_RS29790	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC609_RS29805	COG0583	DNA-binding transcription factor activity
EC609_RS29815	COG0783	Belongs to the Dps family
EC609_RS29825	COG2879	small protein
EC609_RS29830	COG1966	Carbon starvation protein
EC609_RS29855	COG4521	taurine ABC transporter
EC609_RS29860	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EC609_RS29865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS29875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS29905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS29910	COG0601	transmembrane transport
EC609_RS29915	COG0747	negative chemotaxis
EC609_RS29930	COG1414	Transcriptional regulator
EC609_RS29935	COG0513	Belongs to the DEAD box helicase family
EC609_RS29960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS29985	COG2814	Major facilitator Superfamily
EC609_RS29990	COG0386	Belongs to the glutathione peroxidase family
EC609_RS29995	COG1522	sequence-specific DNA binding
EC609_RS30005	COG0625	glutathione transferase activity
EC609_RS30030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC609_RS30035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EC609_RS30040	COG0010	Belongs to the arginase family
EC609_RS30045	COG1126	abc transporter atp-binding protein
EC609_RS30050	COG0765	amino acid transport
EC609_RS30055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC609_RS30065	COG0154	amidase activity
EC609_RS30095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS30100	COG1024	Enoyl-CoA hydratase
EC609_RS30110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EC609_RS30125	COG0084	hydrolase, TatD family'
EC609_RS30130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EC609_RS30135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EC609_RS30140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EC609_RS30165	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS30165	COG1024	Enoyl-CoA hydratase
EC609_RS30170	COG1960	acyl-CoA dehydrogenase activity
EC609_RS30175	COG2914	Belongs to the UPF0125 (RnfH) family
EC609_RS30180	COG2867	negative regulation of translational initiation
EC609_RS30185	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EC609_RS30195	COG0330	HflC and HflK could
EC609_RS30205	COG0519	Catalyzes the synthesis of GMP from XMP
EC609_RS30205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EC609_RS30210	COG2169	Transcriptional regulator
EC609_RS30210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC609_RS30235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC609_RS30240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EC609_RS30255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EC609_RS30260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC609_RS30265	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EC609_RS30270	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC609_RS30275	COG0750	zinc metalloprotease
EC609_RS30280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EC609_RS30285	COG0575	Belongs to the CDS family
EC609_RS30290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EC609_RS30295	COG0233	cytoplasmic translational termination
EC609_RS30300	COG0528	UMP kinase activity
EC609_RS30305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EC609_RS30310	COG0052	Belongs to the universal ribosomal protein uS2 family
EC609_RS30315	COG0024	Methionine aminopeptidase
EC609_RS30320	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EC609_RS30330	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EC609_RS30335	COG1451	nucleotide metabolic process
EC609_RS30355	COG1286	toxin biosynthetic process
EC609_RS30365	COG0285	dihydrofolate synthase activity
EC609_RS30375	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS30380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS30395	COG1334	flagellar protein FlaG
EC609_RS30420	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EC609_RS30430	COG1677	Flagellar hook-basal body complex protein FliE
EC609_RS30440	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EC609_RS30445	COG1317	bacterial-type flagellum organization
EC609_RS30450	COG1157	protein secretion by the type III secretion system
EC609_RS30465	COG1580	Controls the rotational direction of flagella during chemotaxis
EC609_RS30475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EC609_RS30500	COG0840	transmembrane signaling receptor activity
EC609_RS30505	COG0840	transmembrane signaling receptor activity
EC609_RS30515	COG0840	transmembrane signaling receptor activity
EC609_RS30520	COG0840	transmembrane signaling receptor activity
EC609_RS30530	COG1256	bacterial-type flagellum assembly
EC609_RS30555	COG4787	bacterial-type flagellum-dependent cell motility
EC609_RS30570	COG1558	bacterial-type flagellum-dependent cell motility
EC609_RS30575	COG1815	bacterial-type flagellum-dependent cell motility
EC609_RS30585	COG2747	anti-sigma28 factor FlgM
EC609_RS30600	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EC609_RS30615	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EC609_RS30625	COG2201	protein-glutamate methylesterase activity
EC609_RS30630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EC609_RS30635	COG0840	transmembrane signaling receptor activity
EC609_RS30640	COG0835	chemotaxis
EC609_RS30650	COG0745	RESPONSE REGULATOR receiver
EC609_RS30675	COG1191	sigma factor activity
EC609_RS30700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC609_RS30705	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC609_RS30720	COG4566	intracellular signal transduction
EC609_RS30725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EC609_RS30730	COG0339	signal peptide processing
EC609_RS30735	COG1999	signal sequence binding
EC609_RS30765	COG1187	pseudouridine synthase activity
EC609_RS30770	COG3161	chorismate lyase activity
EC609_RS30795	COG1335	isochorismatase
EC609_RS30810	COG0066	3-isopropylmalate dehydratase activity
EC609_RS30815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EC609_RS30845	COG2188	Transcriptional regulator
EC609_RS30880	COG4681	YaeQ
EC609_RS30885	COG1280	lysine exporter protein (LysE YggA)
EC609_RS30895	COG4172	Belongs to the ABC transporter superfamily
EC609_RS30900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS30905	COG0601	transmembrane transport
EC609_RS30910	COG0747	negative chemotaxis
EC609_RS30920	COG0583	DNA-binding transcription factor activity
EC609_RS31010	COG0668	transmembrane transport
EC609_RS31015	COG0165	Argininosuccinate lyase
EC609_RS31020	COG0583	DNA-binding transcription factor activity
EC609_RS31025	COG2814	Major facilitator Superfamily
EC609_RS31040	COG0154	amidase activity
EC609_RS31045	COG0583	DNA-binding transcription factor activity
EC609_RS31060	COG0022	dehydrogenase e1 component
EC609_RS31065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EC609_RS31070	COG1960	acyl-CoA dehydrogenase activity
EC609_RS31075	COG1309	transcriptional regulator
EC609_RS31085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS31095	COG0154	amidase activity
EC609_RS31100	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS31105	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS31120	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC609_RS31125	COG3842	ATPase activity
EC609_RS31145	COG0789	Transcriptional regulator
EC609_RS31165	COG0840	transmembrane signaling receptor activity
EC609_RS31190	COG0307	riboflavin synthase, alpha
EC609_RS31200	COG2186	Transcriptional regulator
EC609_RS31205	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS31230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EC609_RS31235	COG0560	Phosphoserine phosphatase
EC609_RS31245	COG1609	Transcriptional regulator
EC609_RS31265	COG0411	ABC transporter
EC609_RS31275	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC609_RS31285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EC609_RS31290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EC609_RS31295	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS31355	COG2814	Major facilitator Superfamily
EC609_RS31370	COG0583	DNA-binding transcription factor activity
EC609_RS31400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC609_RS31485	COG1309	transcriptional regulator
EC609_RS31495	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS31500	COG3706	GGDEF domain
EC609_RS31505	COG0387	Pfam Sodium calcium exchanger
EC609_RS31515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EC609_RS31545	COG0697	spore germination
EC609_RS31550	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS31555	COG4977	sequence-specific DNA binding
EC609_RS31560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC609_RS31575	COG0583	DNA-binding transcription factor activity
EC609_RS31580	COG0109	protoheme IX farnesyltransferase activity
EC609_RS31590	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS31645	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS31665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EC609_RS31675	COG1802	Transcriptional regulator
EC609_RS31680	COG5265	(ABC) transporter
EC609_RS31685	COG1280	lysine exporter protein (LysE YggA)
EC609_RS31700	COG4977	sequence-specific DNA binding
EC609_RS31720	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS31725	COG2188	Transcriptional regulator
EC609_RS31740	COG0477	Major facilitator Superfamily
EC609_RS31745	COG0235	Class ii aldolase
EC609_RS31755	COG1051	belongs to the nudix hydrolase family
EC609_RS31770	COG2223	nitrite transmembrane transporter activity
EC609_RS31780	COG2610	gluconate transmembrane transporter activity
EC609_RS31785	COG0583	DNA-binding transcription factor activity
EC609_RS31790	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS31795	COG1024	Enoyl-CoA hydratase
EC609_RS31800	COG5001	Diguanylate cyclase
EC609_RS31805	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS31810	COG0129	dihydroxy-acid dehydratase activity
EC609_RS31835	COG0765	amino acid transport
EC609_RS31870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC609_RS31880	COG4771	TonB-dependent receptor
EC609_RS31885	COG1429	ligase activity, forming nitrogen-metal bonds
EC609_RS31950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EC609_RS31955	COG0583	DNA-binding transcription factor activity
EC609_RS31960	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC609_RS31965	COG3246	L-lysine catabolic process to acetate
EC609_RS31990	COG3005	denitrification pathway
EC609_RS31995	COG4133	protoheme IX ABC transporter activity
EC609_RS32015	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EC609_RS32025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC609_RS32075	COG2207	Transcriptional regulator
EC609_RS32080	COG1064	alcohol dehydrogenase
EC609_RS32120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC609_RS32130	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS32145	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS32155	COG2188	Transcriptional regulator
EC609_RS32185	COG1137	ATPase activity
EC609_RS32190	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EC609_RS32205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EC609_RS32215	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS32220	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EC609_RS32235	COG0697	spore germination
EC609_RS32260	COG1280	lysine exporter protein (LysE YggA)
EC609_RS32275	COG1280	lysine exporter protein (LysE YggA)
EC609_RS32285	COG3245	cytochrome
EC609_RS32295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC609_RS32325	COG0318	PFAM AMP-dependent synthetase and ligase
EC609_RS32330	COG1960	acyl-CoA dehydrogenase activity
EC609_RS32335	COG2814	Major facilitator Superfamily
EC609_RS32350	COG0625	glutathione transferase activity
EC609_RS32375	COG0506	proline dehydrogenase activity
EC609_RS32380	COG0697	spore germination
EC609_RS32385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC609_RS32390	COG1959	2 iron, 2 sulfur cluster binding
EC609_RS32400	COG1610	YqeY-like protein
EC609_RS32435	COG0457	Tetratricopeptide repeat
EC609_RS32440	COG1649	PFAM Uncharacterised BCR, COG1649
EC609_RS32440	COG0726	polysaccharide deacetylase
EC609_RS32450	COG3658	cytochrome
EC609_RS32455	COG2223	nitrite transmembrane transporter activity
EC609_RS32460	COG4977	sequence-specific DNA binding
EC609_RS32460	COG1917	Cupin 2, conserved barrel domain protein
EC609_RS32470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EC609_RS32485	COG0656	L-ascorbic acid biosynthetic process
EC609_RS32520	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS32560	COG1522	sequence-specific DNA binding
EC609_RS32585	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS32595	COG0456	acetyltransferase
EC609_RS32600	COG0384	phenazine biosynthesis protein PhzF
EC609_RS32605	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS32610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC609_RS32630	COG3181	Tripartite tricarboxylate transporter family receptor
EC609_RS32635	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EC609_RS32670	COG5002	protein histidine kinase activity
EC609_RS32695	COG1028	Short-chain dehydrogenase reductase Sdr
EC609_RS32720	COG0776	regulation of translation
EC609_RS32725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EC609_RS32725	COG0072	phenylalanine-tRNA ligase activity
EC609_RS32730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EC609_RS32735	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EC609_RS32740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EC609_RS32750	COG2960	long-chain fatty acid transporting porin activity
EC609_RS32770	COG0640	Transcriptional regulator
EC609_RS32775	COG0347	Belongs to the P(II) protein family
EC609_RS32785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EC609_RS32790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC609_RS32805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EC609_RS32820	COG2197	response regulator
EC609_RS32825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC609_RS32850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC609_RS32865	COG0129	dihydroxy-acid dehydratase activity
EC609_RS32910	COG1278	Cold shock
EC609_RS32920	COG0135	phosphoribosylanthranilate isomerase activity
EC609_RS32925	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EC609_RS32930	COG0101	tRNA pseudouridine synthase activity
EC609_RS32940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EC609_RS32960	COG1538	Outer membrane efflux protein
EC609_RS32975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family