locus-tag	class	description
MC81_RS00010	COG1530	ribonuclease E activity
MC81_RS00025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MC81_RS00030	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MC81_RS00035	COG3023	N-Acetylmuramoyl-L-alanine amidase
MC81_RS00045	COG0424	maF-like protein
MC81_RS00050	COG1399	metal-binding, possibly nucleic acid-binding protein
MC81_RS00055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MC81_RS00060	COG0416	fatty acid biosynthetic process
MC81_RS00065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MC81_RS00070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MC81_RS00080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MC81_RS00085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MC81_RS00110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MC81_RS00120	COG0681	Belongs to the peptidase S26 family
MC81_RS00125	COG0571	ribonuclease III activity
MC81_RS00130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MC81_RS00135	COG1381	Involved in DNA repair and RecF pathway recombination
MC81_RS00145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MC81_RS00155	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS00185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MC81_RS00210	COG0583	DNA-binding transcription factor activity
MC81_RS00220	COG0791	NLP P60 protein
MC81_RS00225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MC81_RS00230	COG3193	protein, possibly involved in utilization of glycolate and propanediol
MC81_RS00240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MC81_RS00245	COG0697	spore germination
MC81_RS00250	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
MC81_RS00255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MC81_RS00270	COG0747	negative chemotaxis
MC81_RS00300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MC81_RS00325	COG2153	protein acetylation
MC81_RS00335	COG1446	asparaginase
MC81_RS00340	COG4172	Belongs to the ABC transporter superfamily
MC81_RS00345	COG0747	negative chemotaxis
MC81_RS00355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS00380	COG0504	CTP synthase activity
MC81_RS00395	COG0148	phosphopyruvate hydratase activity
MC81_RS00410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MC81_RS00420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MC81_RS00450	COG1981	membrane
MC81_RS00470	COG0039	L-malate dehydrogenase activity
MC81_RS00475	COG2188	Transcriptional regulator
MC81_RS00480	COG2009	succinate dehydrogenase
MC81_RS00485	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MC81_RS00490	COG1053	succinate dehydrogenase
MC81_RS00495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MC81_RS00505	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MC81_RS00510	COG0372	Belongs to the citrate synthase family
MC81_RS00525	COG0281	malic enzyme
MC81_RS00525	COG0280	phosphate acetyltransferase
MC81_RS00535	COG1297	OPT oligopeptide transporter protein
MC81_RS00540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_RS00555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MC81_RS00560	COG1522	sequence-specific DNA binding
MC81_RS00565	COG0567	Dehydrogenase, E1 component
MC81_RS00570	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_RS00575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_RS00580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MC81_RS00585	COG1595	DNA-templated transcription, initiation
MC81_RS00590	COG3712	iron ion homeostasis
MC81_RS00595	COG4774	siderophore transport
MC81_RS00630	COG2183	response to ionizing radiation
MC81_RS00635	COG1199	ATP-dependent helicase activity
MC81_RS00655	COG0564	pseudouridine synthase activity
MC81_RS00660	COG1496	oxidoreductase activity
MC81_RS00665	COG3243	poly(R)-hydroxyalkanoic acid synthase
MC81_RS00670	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS00675	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
MC81_RS00695	COG0672	)-iron permease
MC81_RS00710	COG2823	Periplasmic or secreted lipoprotein
MC81_RS00720	COG3237	CsbD-like
MC81_RS00725	COG0189	ligase activity
MC81_RS00725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MC81_RS00730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MC81_RS00730	COG0189	ligase activity
MC81_RS00735	COG1132	(ABC) transporter
MC81_RS00750	COG2833	Protein of unknown function (DUF455)
MC81_RS00755	COG2951	lytic endotransglycosylase activity
MC81_RS00775	COG1215	transferase activity, transferring glycosyl groups
MC81_RS00785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MC81_RS00790	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS00810	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS00815	COG1024	Enoyl-CoA hydratase
MC81_RS00820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS00830	COG1960	acyl-CoA dehydrogenase activity
MC81_RS00835	COG0045	succinate-CoA ligase (ADP-forming) activity
MC81_RS00845	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS00855	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS00860	COG2030	dehydratase
MC81_RS00870	COG1960	acyl-CoA dehydrogenase activity
MC81_RS00900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MC81_RS00915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MC81_RS00920	COG0077	Prephenate dehydratase
MC81_RS00920	COG1605	Chorismate mutase
MC81_RS00925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MC81_RS00930	COG0287	Prephenate dehydrogenase
MC81_RS00935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MC81_RS00940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MC81_RS00960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MC81_RS00965	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MC81_RS00970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC81_RS01000	COG2951	lytic endotransglycosylase activity
MC81_RS01005	COG0123	including yeast histone deacetylase and acetoin utilization protein
MC81_RS01030	COG2985	domain, Protein
MC81_RS01040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS01045	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS01045	COG1024	Enoyl-CoA hydratase
MC81_RS01055	COG1960	acyl-CoA dehydrogenase activity
MC81_RS01060	COG0450	alkyl hydroperoxide reductase
MC81_RS01065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MC81_RS01070	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MC81_RS01075	COG4208	sulfate ABC transporter
MC81_RS01080	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MC81_RS01085	COG0175	sulfate reduction
MC81_RS01115	COG0335	large ribosomal subunit rRNA binding
MC81_RS01125	COG1162	GTPase activity
MC81_RS01130	COG0501	Belongs to the peptidase M48B family
MC81_RS01135	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MC81_RS01140	COG2204	response regulator
MC81_RS01160	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MC81_RS01165	COG3327	negative regulation of DNA-templated transcription, initiation
MC81_RS01170	COG3396	Phenylacetate-CoA oxygenase
MC81_RS01175	COG3460	Phenylacetate-CoA oxygenase
MC81_RS01180	COG3396	Phenylacetate-CoA oxygenase
MC81_RS01185	COG2151	metal-sulfur cluster biosynthetic enzyme
MC81_RS01190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_RS01195	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS01200	COG1024	Enoyl-CoA hydratase
MC81_RS01205	COG2050	protein possibly involved in aromatic compounds catabolism
MC81_RS01230	COG3483	tryptophan 2,3-dioxygenase activity
MC81_RS01235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MC81_RS01240	COG2003	Belongs to the UPF0758 family
MC81_RS01245	COG1047	Peptidyl-prolyl cis-trans
MC81_RS01250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MC81_RS01255	COG0625	glutathione transferase activity
MC81_RS01260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MC81_RS01265	COG0642	Histidine kinase
MC81_RS01285	COG0523	cobalamin synthesis protein
MC81_RS01290	COG0583	DNA-binding transcription factor activity
MC81_RS01300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MC81_RS01305	COG1187	pseudouridine synthase activity
MC81_RS01310	COG0779	Required for maturation of 30S ribosomal subunits
MC81_RS01315	COG0195	Participates in both transcription termination and antitermination
MC81_RS01315	COG2251	uridine kinase activity
MC81_RS01320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MC81_RS01325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MC81_RS01330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MC81_RS01335	COG1217	gtp-binding protein TYPA
MC81_RS01345	COG0583	DNA-binding transcription factor activity
MC81_RS01350	COG0583	DNA-binding transcription factor activity
MC81_RS01365	COG2271	Major facilitator Superfamily
MC81_RS01370	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS01385	COG1473	amidohydrolase
MC81_RS01400	COG0428	transporter
MC81_RS01405	COG0412	Dienelactone hydrolase
MC81_RS01410	COG1283	sodium-dependent phosphate transmembrane transporter activity
MC81_RS01415	COG1760	l-serine dehydratase
MC81_RS01420	COG0501	Belongs to the peptidase M48B family
MC81_RS01435	COG0583	DNA-binding transcription factor activity
MC81_RS01455	COG3842	ATPase activity
MC81_RS01465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC81_RS01470	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_RS01500	COG1722	exodeoxyribonuclease VII activity
MC81_RS01505	COG0142	geranyltranstransferase activity
MC81_RS01515	COG1469	GTP cyclohydrolase I activity
MC81_RS01520	COG3739	integral membrane protein
MC81_RS01525	COG0360	Binds together with S18 to 16S ribosomal RNA
MC81_RS01530	COG2965	DNA replication, synthesis of RNA primer
MC81_RS01535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MC81_RS01540	COG0359	binds to the 23S rRNA
MC81_RS01550	COG0305	Participates in initiation and elongation during chromosome replication
MC81_RS01560	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MC81_RS01595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS01615	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
MC81_RS01645	COG0540	Belongs to the ATCase OTCase family
MC81_RS01680	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MC81_RS01685	COG2137	regulation of response to DNA damage stimulus
MC81_RS01695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MC81_RS01710	COG0045	succinate-CoA ligase (ADP-forming) activity
MC81_RS01715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MC81_RS01720	COG0861	Integral membrane protein TerC family
MC81_RS01725	COG0861	Integral membrane protein TerC family
MC81_RS01730	COG0181	hydroxymethylbilane synthase activity
MC81_RS01750	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MC81_RS01760	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS01790	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_RS01810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MC81_RS01815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MC81_RS01825	COG0436	Aminotransferase
MC81_RS01845	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MC81_RS01850	COG0308	aminopeptidase N
MC81_RS01865	COG0312	modulator of DNA gyrase
MC81_RS01870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MC81_RS01875	COG0277	FAD linked oxidase domain protein
MC81_RS01880	COG0277	FAD linked oxidase domain protein
MC81_RS01885	COG0277	FAD linked oxidase domain protein
MC81_RS01890	COG0247	lactate metabolic process
MC81_RS01920	COG0583	DNA-binding transcription factor activity
MC81_RS01925	COG0482	sulfurtransferase activity
MC81_RS01930	COG0730	response to heat
MC81_RS01935	COG0625	glutathione transferase activity
MC81_RS01945	COG3909	cytochrome
MC81_RS02005	COG0697	spore germination
MC81_RS02050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC81_RS02055	COG0069	glutamate synthase activity
MC81_RS02060	COG2391	methyltransferase activity
MC81_RS02065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MC81_RS02100	COG0557	exoribonuclease II activity
MC81_RS02105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MC81_RS02110	COG0626	cystathionine gamma-synthase activity
MC81_RS02115	COG3128	pkhd-type hydroxylase
MC81_RS02120	COG0776	regulation of translation
MC81_RS02150	COG0642	Histidine kinase
MC81_RS02155	COG3158	transport of potassium into the cell
MC81_RS02160	COG0137	argininosuccinate synthase activity
MC81_RS02165	COG0583	DNA-binding transcription factor activity
MC81_RS02190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MC81_RS02195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MC81_RS02215	COG0747	negative chemotaxis
MC81_RS02220	COG0601	transmembrane transport
MC81_RS02225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS02235	COG1228	amidohydrolase
MC81_RS02240	COG0444	Belongs to the ABC transporter superfamily
MC81_RS02245	COG4608	Belongs to the ABC transporter superfamily
MC81_RS02250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MC81_RS02250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_RS02260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_RS02265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MC81_RS02275	COG3642	lipopolysaccharide core region biosynthetic process
MC81_RS02285	COG3842	ATPase activity
MC81_RS02290	COG1176	ABC-type spermidine putrescine transport system, permease component I
MC81_RS02295	COG1177	transmembrane transport
MC81_RS02305	COG2094	Belongs to the DNA glycosylase MPG family
MC81_RS02325	COG1960	acyl-CoA dehydrogenase activity
MC81_RS02330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MC81_RS02335	COG0704	Plays a role in the regulation of phosphate uptake
MC81_RS02345	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MC81_RS02350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MC81_RS02350	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MC81_RS02355	COG1643	Atp-dependent helicase
MC81_RS02370	COG0438	transferase activity, transferring glycosyl groups
MC81_RS02375	COG0726	polysaccharide deacetylase
MC81_RS02390	COG0726	polysaccharide deacetylase
MC81_RS02415	COG1132	(ABC) transporter
MC81_RS02420	COG0475	glutathione-regulated potassium exporter activity
MC81_RS02420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MC81_RS02430	COG2203	Gaf domain
MC81_RS02430	COG4251	negative regulation of phosphorylation
MC81_RS02430	COG5001	Diguanylate cyclase
MC81_RS02430	COG3706	GGDEF domain
MC81_RS02450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_RS02450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MC81_RS02455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_RS02460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC81_RS02520	COG3723	Recombinational DNA repair protein, rece pathway
MC81_RS02740	COG1530	ribonuclease E activity
MC81_RS02770	COG2204	response regulator
MC81_RS02775	COG4191	Histidine kinase
MC81_RS02780	COG1301	dicarboxylic acid transport
MC81_RS02790	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MC81_RS02795	COG0799	negative regulation of ribosome biogenesis
MC81_RS02800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MC81_RS02810	COG0151	Belongs to the GarS family
MC81_RS02815	COG0217	transcriptional regulatory protein
MC81_RS02820	COG0433	COG0433 Predicted ATPase
MC81_RS02825	COG0473	3-isopropylmalate dehydrogenase activity
MC81_RS02835	COG2814	Major facilitator Superfamily
MC81_RS02840	COG1566	PFAM secretion protein HlyD family protein
MC81_RS02850	COG1846	Transcriptional regulator
MC81_RS02880	COG3391	amine dehydrogenase activity
MC81_RS02890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MC81_RS02910	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MC81_RS02915	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MC81_RS02925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MC81_RS02955	COG2311	Membrane
MC81_RS02965	COG2358	TRAP transporter, solute receptor (TAXI family
MC81_RS02970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MC81_RS02995	COG0662	Cupin 2, conserved barrel domain protein
MC81_RS03000	COG5285	phytanoyl-CoA dioxygenase
MC81_RS03005	COG0633	Ferredoxin
MC81_RS03005	COG3217	Mosc domain protein beta barrel domain protein
MC81_RS03010	COG2076	Multidrug Resistance protein
MC81_RS03025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS03075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MC81_RS03080	COG0425	Belongs to the sulfur carrier protein TusA family
MC81_RS03090	COG0228	four-way junction DNA binding
MC81_RS03095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MC81_RS03100	COG0336	Belongs to the RNA methyltransferase TrmD family
MC81_RS03105	COG0525	valine-tRNA ligase activity
MC81_RS03110	COG0105	UTP biosynthetic process
MC81_RS03115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MC81_RS03135	COG2976	Protein conserved in bacteria
MC81_RS03140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC81_RS03145	COG1160	GTP binding
MC81_RS03150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MC81_RS03155	COG1923	regulation of RNA biosynthetic process
MC81_RS03160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MC81_RS03165	COG0330	HflC and HflK could
MC81_RS03170	COG0330	HflC and HflK could
MC81_RS03175	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MC81_RS03180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MC81_RS03185	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
MC81_RS03190	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MC81_RS03200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MC81_RS03230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MC81_RS03245	COG0583	DNA-binding transcription factor activity
MC81_RS03285	COG4964	Belongs to the GSP D family
MC81_RS03320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MC81_RS03330	COG1295	ribonuclease BN
MC81_RS03340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MC81_RS03365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MC81_RS03435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_RS03440	COG2274	protein secretion by the type I secretion system
MC81_RS03450	COG1538	Outer membrane efflux protein
MC81_RS03470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MC81_RS03485	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MC81_RS03490	COG0135	phosphoribosylanthranilate isomerase activity
MC81_RS03500	COG0582	viral genome integration into host DNA
MC81_RS03660	COG3728	DNA packaging
MC81_RS03665	COG1783	phage Terminase large subunit
MC81_RS03820	COG2203	Gaf domain
MC81_RS03820	COG2199	diguanylate cyclase activity
MC81_RS03830	COG0840	transmembrane signaling receptor activity
MC81_RS03840	COG0129	dihydroxy-acid dehydratase activity
MC81_RS03845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_RS03850	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_RS03855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MC81_RS03860	COG1609	Transcriptional regulator
MC81_RS03885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS03890	COG0601	transmembrane transport
MC81_RS03915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MC81_RS03925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MC81_RS03930	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MC81_RS03945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC81_RS03950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MC81_RS03955	COG0004	ammonium transporteR
MC81_RS03960	COG0347	Belongs to the P(II) protein family
MC81_RS03970	COG2960	long-chain fatty acid transporting porin activity
MC81_RS03975	COG0606	chelatase, subunit chli
MC81_RS03980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MC81_RS03985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MC81_RS03990	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MC81_RS03995	COG0072	phenylalanine-tRNA ligase activity
MC81_RS03995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MC81_RS04000	COG0776	regulation of translation
MC81_RS04015	COG0789	Transcriptional regulator
MC81_RS04020	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MC81_RS04045	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS04050	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS04055	COG0129	dihydroxy-acid dehydratase activity
MC81_RS04060	COG0583	DNA-binding transcription factor activity
MC81_RS04065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MC81_RS04075	COG0384	phenazine biosynthesis protein PhzF
MC81_RS04080	COG0456	acetyltransferase
MC81_RS04090	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS04115	COG1522	sequence-specific DNA binding
MC81_RS04155	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS04180	COG1116	anion transmembrane transporter activity
MC81_RS04195	COG0583	DNA-binding transcription factor activity
MC81_RS04210	COG5265	(ABC) transporter
MC81_RS04215	COG0656	L-ascorbic acid biosynthetic process
MC81_RS04230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MC81_RS04240	COG4977	sequence-specific DNA binding
MC81_RS04240	COG1917	Cupin 2, conserved barrel domain protein
MC81_RS04245	COG2223	nitrite transmembrane transporter activity
MC81_RS04255	COG1215	transferase activity, transferring glycosyl groups
MC81_RS04260	COG1649	PFAM Uncharacterised BCR, COG1649
MC81_RS04260	COG0726	polysaccharide deacetylase
MC81_RS04265	COG0457	Tetratricopeptide repeat
MC81_RS04310	COG1610	YqeY-like protein
MC81_RS04325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS04330	COG0697	spore germination
MC81_RS04335	COG0506	proline dehydrogenase activity
MC81_RS04350	COG0583	DNA-binding transcription factor activity
MC81_RS04355	COG0583	DNA-binding transcription factor activity
MC81_RS04360	COG0625	glutathione transferase activity
MC81_RS04375	COG2814	Major facilitator Superfamily
MC81_RS04380	COG3328	transposase activity
MC81_RS04385	COG1960	acyl-CoA dehydrogenase activity
MC81_RS04390	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS04415	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MC81_RS04435	COG1280	lysine exporter protein (LysE YggA)
MC81_RS04445	COG0583	DNA-binding transcription factor activity
MC81_RS04455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS04460	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS04465	COG0183	Belongs to the thiolase family
MC81_RS04485	COG0697	spore germination
MC81_RS04490	COG0697	spore germination
MC81_RS04505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MC81_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS04520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MC81_RS04525	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MC81_RS04535	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MC81_RS04540	COG1129	ABC transporter
MC81_RS04565	COG0154	amidase activity
MC81_RS04570	COG2186	Transcriptional regulator
MC81_RS04580	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS04585	COG2084	Dehydrogenase
MC81_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS04605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_RS04695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_RS04705	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MC81_RS04725	COG4133	protoheme IX ABC transporter activity
MC81_RS04730	COG3005	denitrification pathway
MC81_RS04735	COG3043	anaerobic respiration
MC81_RS04755	COG3246	L-lysine catabolic process to acetate
MC81_RS04760	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS04765	COG0583	DNA-binding transcription factor activity
MC81_RS04780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MC81_RS04790	COG0596	Alpha beta hydrolase
MC81_RS04795	COG2309	aminopeptidase activity
MC81_RS04800	COG1335	isochorismatase
MC81_RS04805	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MC81_RS04825	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MC81_RS04850	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_RS04855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS04870	COG2226	methyltransferase
MC81_RS04890	COG0129	dihydroxy-acid dehydratase activity
MC81_RS04895	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS04900	COG5001	Diguanylate cyclase
MC81_RS04905	COG1024	Enoyl-CoA hydratase
MC81_RS04910	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS04915	COG0583	DNA-binding transcription factor activity
MC81_RS04920	COG2610	gluconate transmembrane transporter activity
MC81_RS04940	COG0583	DNA-binding transcription factor activity
MC81_RS04945	COG1051	belongs to the nudix hydrolase family
MC81_RS04955	COG0235	Class ii aldolase
MC81_RS04960	COG0477	Major facilitator Superfamily
MC81_RS04980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MC81_RS04995	COG2188	Transcriptional regulator
MC81_RS05040	COG1280	lysine exporter protein (LysE YggA)
MC81_RS05045	COG5265	(ABC) transporter
MC81_RS05050	COG1802	Transcriptional regulator
MC81_RS05085	COG0411	ABC transporter
MC81_RS05095	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS05115	COG0640	Transcriptional regulator
MC81_RS05130	COG0251	oxidation-reduction process
MC81_RS05135	COG0583	DNA-binding transcription factor activity
MC81_RS05145	COG3712	iron ion homeostasis
MC81_RS05150	COG1595	DNA-templated transcription, initiation
MC81_RS05180	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS05185	COG0183	Belongs to the thiolase family
MC81_RS05255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MC81_RS05265	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS05270	COG0183	Belongs to the thiolase family
MC81_RS05280	COG0583	DNA-binding transcription factor activity
MC81_RS05345	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS05350	COG2186	Transcriptional regulator
MC81_RS05360	COG0307	riboflavin synthase, alpha
MC81_RS05375	COG2271	Major facilitator Superfamily
MC81_RS05385	COG0840	transmembrane signaling receptor activity
MC81_RS05410	COG0789	Transcriptional regulator
MC81_RS05415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS05420	COG2186	Transcriptional regulator
MC81_RS05425	COG1024	Enoyl-CoA hydratase
MC81_RS05450	COG0022	dehydrogenase e1 component
MC81_RS05465	COG0583	DNA-binding transcription factor activity
MC81_RS05470	COG0154	amidase activity
MC81_RS05500	COG0477	Major facilitator Superfamily
MC81_RS05530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_RS05540	COG2814	Major facilitator Superfamily
MC81_RS05545	COG0583	DNA-binding transcription factor activity
MC81_RS05550	COG1598	PFAM Uncharacterised protein family UPF0150
MC81_RS05555	COG0165	Argininosuccinate lyase
MC81_RS05560	COG0668	transmembrane transport
MC81_RS05660	COG0583	DNA-binding transcription factor activity
MC81_RS05670	COG0747	negative chemotaxis
MC81_RS05675	COG0601	transmembrane transport
MC81_RS05680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS05685	COG4172	Belongs to the ABC transporter superfamily
MC81_RS05690	COG1280	lysine exporter protein (LysE YggA)
MC81_RS05695	COG4681	YaeQ
MC81_RS05715	COG2188	Transcriptional regulator
MC81_RS05745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MC81_RS05750	COG0066	3-isopropylmalate dehydratase activity
MC81_RS05780	COG3161	chorismate lyase activity
MC81_RS05825	COG1187	pseudouridine synthase activity
MC81_RS05830	COG0583	DNA-binding transcription factor activity
MC81_RS05855	COG1999	signal sequence binding
MC81_RS05865	COG0339	signal peptide processing
MC81_RS05870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MC81_RS05875	COG4566	intracellular signal transduction
MC81_RS05890	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_RS05895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_RS05915	COG4797	methyltransferase
MC81_RS05915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MC81_RS05920	COG1191	sigma factor activity
MC81_RS05940	COG1360	Flagellar Motor Protein
MC81_RS05945	COG0745	RESPONSE REGULATOR receiver
MC81_RS05955	COG0835	chemotaxis
MC81_RS05960	COG0840	transmembrane signaling receptor activity
MC81_RS05965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MC81_RS05970	COG2201	protein-glutamate methylesterase activity
MC81_RS05975	COG0745	RESPONSE REGULATOR receiver
MC81_RS05980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MC81_RS05990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MC81_RS05995	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MC81_RS06010	COG2747	anti-sigma28 factor FlgM
MC81_RS06020	COG1815	bacterial-type flagellum-dependent cell motility
MC81_RS06025	COG1558	bacterial-type flagellum-dependent cell motility
MC81_RS06040	COG4787	bacterial-type flagellum-dependent cell motility
MC81_RS06060	COG3951	Flagellar rod assembly protein muramidase FlgJ
MC81_RS06060	COG1705	Flagellar rod assembly protein muramidase FlgJ
MC81_RS06065	COG1256	bacterial-type flagellum assembly
MC81_RS06075	COG0840	transmembrane signaling receptor activity
MC81_RS06080	COG0840	transmembrane signaling receptor activity
MC81_RS06090	COG0840	transmembrane signaling receptor activity
MC81_RS06095	COG0840	transmembrane signaling receptor activity
MC81_RS06105	COG1987	bacterial-type flagellum assembly
MC81_RS06120	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MC81_RS06130	COG1580	Controls the rotational direction of flagella during chemotaxis
MC81_RS06145	COG1157	protein secretion by the type III secretion system
MC81_RS06155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MC81_RS06165	COG1677	Flagellar hook-basal body complex protein FliE
MC81_RS06175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MC81_RS06195	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MC81_RS06200	COG1334	flagellar protein FlaG
MC81_RS06215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS06220	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS06230	COG0285	dihydrofolate synthase activity
MC81_RS06240	COG1286	toxin biosynthetic process
MC81_RS06250	COG1451	nucleotide metabolic process
MC81_RS06265	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MC81_RS06270	COG0024	Methionine aminopeptidase
MC81_RS06275	COG0052	Belongs to the universal ribosomal protein uS2 family
MC81_RS06280	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MC81_RS06285	COG0528	UMP kinase activity
MC81_RS06290	COG0233	cytoplasmic translational termination
MC81_RS06295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MC81_RS06300	COG0575	Belongs to the CDS family
MC81_RS06305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MC81_RS06310	COG0750	zinc metalloprotease
MC81_RS06315	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC81_RS06320	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
MC81_RS06325	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MC81_RS06330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MC81_RS06345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MC81_RS06350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MC81_RS06370	COG2169	Transcriptional regulator
MC81_RS06370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MC81_RS06375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MC81_RS06375	COG0519	Catalyzes the synthesis of GMP from XMP
MC81_RS06385	COG0330	HflC and HflK could
MC81_RS06395	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MC81_RS06400	COG2867	negative regulation of translational initiation
MC81_RS06405	COG2914	Belongs to the UPF0125 (RnfH) family
MC81_RS06410	COG1960	acyl-CoA dehydrogenase activity
MC81_RS06415	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MC81_RS06435	COG0354	folic acid binding
MC81_RS06440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MC81_RS06445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MC81_RS06450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MC81_RS06455	COG0084	hydrolase, TatD family'
MC81_RS06470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MC81_RS06480	COG1024	Enoyl-CoA hydratase
MC81_RS06485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS06505	COG1137	ATPase activity
MC81_RS06515	COG0154	amidase activity
MC81_RS06525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS06530	COG0765	amino acid transport
MC81_RS06535	COG1126	abc transporter atp-binding protein
MC81_RS06540	COG0010	Belongs to the arginase family
MC81_RS06545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MC81_RS06550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_RS06560	COG0095	Lipoate-protein ligase
MC81_RS06575	COG0625	glutathione transferase activity
MC81_RS06585	COG1522	sequence-specific DNA binding
MC81_RS06590	COG0386	Belongs to the glutathione peroxidase family
MC81_RS06595	COG2814	Major facilitator Superfamily
MC81_RS06615	COG0840	transmembrane signaling receptor activity
MC81_RS06625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS06645	COG0513	Belongs to the DEAD box helicase family
MC81_RS06650	COG1414	Transcriptional regulator
MC81_RS06670	COG0601	transmembrane transport
MC81_RS06675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS06690	COG1228	amidohydrolase
MC81_RS06715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS06720	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_RS06725	COG4521	taurine ABC transporter
MC81_RS06745	COG1966	Carbon starvation protein
MC81_RS06750	COG2879	small protein
MC81_RS06760	COG0783	Belongs to the Dps family
MC81_RS06770	COG0583	DNA-binding transcription factor activity
MC81_RS06785	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_RS06815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_RS06820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_RS06830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MC81_RS06835	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
MC81_RS06840	COG0745	RESPONSE REGULATOR receiver
MC81_RS06845	COG2205	protein histidine kinase activity
MC81_RS06860	COG2070	2-Nitropropane dioxygenase
MC81_RS06915	COG0583	DNA-binding transcription factor activity
MC81_RS06920	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS06935	COG1021	2,3-dihydroxybenzoate-AMP ligase
MC81_RS06950	COG1309	transcriptional regulator
MC81_RS06955	COG1414	Transcriptional regulator
MC81_RS06960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_RS07045	COG0583	DNA-binding transcription factor activity
MC81_RS07055	COG0387	Pfam Sodium calcium exchanger
MC81_RS07095	COG2223	nitrite transmembrane transporter activity
MC81_RS07100	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MC81_RS07105	COG1140	nitrate reductase beta subunit
MC81_RS07110	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MC81_RS07115	COG2181	nitrate reductase activity
MC81_RS07120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_RS07130	COG0288	reversible hydration of carbon dioxide
MC81_RS07135	COG1763	Mo-molybdopterin cofactor biosynthetic process
MC81_RS07140	COG3850	Histidine kinase
MC81_RS07145	COG2197	response regulator
MC81_RS07150	COG0826	peptidase U32
MC81_RS07155	COG0826	peptidase U32
MC81_RS07160	COG3154	lipid carrier protein
MC81_RS07170	COG4597	amino acid ABC transporter
MC81_RS07175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS07215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_RS07225	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS07230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_RS07235	COG1802	Transcriptional regulator
MC81_RS07270	COG0583	DNA-binding transcription factor activity
MC81_RS07285	COG1960	acyl-CoA dehydrogenase activity
MC81_RS07290	COG4251	negative regulation of phosphorylation
MC81_RS07290	COG2203	Gaf domain
MC81_RS07290	COG5001	Diguanylate cyclase
MC81_RS07290	COG3706	GGDEF domain
MC81_RS07300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MC81_RS07310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MC81_RS07330	COG3485	protocatechuate 3,4-dioxygenase
MC81_RS07345	COG1073	alpha beta
MC81_RS07355	COG2084	Dehydrogenase
MC81_RS07370	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS07375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS07395	COG0604	alcohol dehydrogenase
MC81_RS07395	COG3321	synthase
MC81_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS07415	COG0765	amino acid transport
MC81_RS07425	COG1126	abc transporter atp-binding protein
MC81_RS07440	COG0583	DNA-binding transcription factor activity
MC81_RS07460	COG4566	intracellular signal transduction
MC81_RS07485	COG0583	DNA-binding transcription factor activity
MC81_RS07490	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MC81_RS07520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_RS07530	COG0028	Belongs to the TPP enzyme family
MC81_RS07545	COG0346	lactoylglutathione lyase activity
MC81_RS07555	COG0596	Alpha beta hydrolase
MC81_RS07560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_RS07580	COG1126	abc transporter atp-binding protein
MC81_RS07585	COG0010	Belongs to the arginase family
MC81_RS07590	COG0765	amino acid transport
MC81_RS07610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS07615	COG0765	amino acid transport
MC81_RS07620	COG1126	abc transporter atp-binding protein
MC81_RS07645	COG0390	transport system, permease component
MC81_RS07650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MC81_RS07660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC81_RS07675	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS07680	COG0583	DNA-binding transcription factor activity
MC81_RS07690	COG0235	Class ii aldolase
MC81_RS07700	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS07710	COG0028	Belongs to the TPP enzyme family
MC81_RS07720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MC81_RS07720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_RS07730	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_RS07740	COG4608	Belongs to the ABC transporter superfamily
MC81_RS07745	COG0444	Belongs to the ABC transporter superfamily
MC81_RS07750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS07760	COG0747	negative chemotaxis
MC81_RS07780	COG0583	DNA-binding transcription factor activity
MC81_RS07790	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS07795	COG3485	protocatechuate 3,4-dioxygenase
MC81_RS07800	COG1063	alcohol dehydrogenase
MC81_RS07805	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS07830	COG0583	DNA-binding transcription factor activity
MC81_RS07835	COG1335	isochorismatase
MC81_RS07840	COG0583	DNA-binding transcription factor activity
MC81_RS07850	COG0477	Major facilitator Superfamily
MC81_RS07855	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS07930	COG1414	Transcriptional regulator
MC81_RS07960	COG0395	ABC-type sugar transport system, permease component
MC81_RS07965	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS07970	COG3842	ATPase activity
MC81_RS07985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MC81_RS07990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_RS08010	COG0431	NADPH-dependent FMN reductase
MC81_RS08035	COG2271	Major facilitator Superfamily
MC81_RS08040	COG2186	Transcriptional regulator
MC81_RS08045	COG0154	amidase activity
MC81_RS08050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS08055	COG1024	Enoyl-CoA hydratase
MC81_RS08070	COG0625	glutathione transferase activity
MC81_RS08085	COG0531	amino acid
MC81_RS08095	COG1960	acyl-CoA dehydrogenase activity
MC81_RS08145	COG0583	DNA-binding transcription factor activity
MC81_RS08160	COG1619	proteins homologs of microcin C7 resistance protein MccF
MC81_RS08170	COG0628	permease
MC81_RS08185	COG3706	GGDEF domain
MC81_RS08215	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MC81_RS08225	COG2205	protein histidine kinase activity
MC81_RS08260	COG3119	arylsulfatase activity
MC81_RS08295	COG0714	Associated with various cellular activities
MC81_RS08300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MC81_RS08310	COG1253	flavin adenine dinucleotide binding
MC81_RS08325	COG4172	Belongs to the ABC transporter superfamily
MC81_RS08330	COG3568	Endonuclease Exonuclease Phosphatase
MC81_RS08335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC81_RS08340	COG0392	lysyltransferase activity
MC81_RS08360	COG0028	Belongs to the TPP enzyme family
MC81_RS08365	COG0297	glycogen (starch) synthase activity
MC81_RS08370	COG0366	Alpha amylase catalytic
MC81_RS08380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MC81_RS08390	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MC81_RS08395	COG1640	4-alpha-glucanotransferase
MC81_RS08405	COG3300	MHYT domain
MC81_RS08405	COG5001	Diguanylate cyclase
MC81_RS08410	COG1289	transmembrane transporter activity
MC81_RS08420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MC81_RS08480	COG2204	response regulator
MC81_RS08485	COG2204	response regulator
MC81_RS08490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MC81_RS08505	COG2814	Major facilitator Superfamily
MC81_RS08520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_RS08525	COG2199	diguanylate cyclase activity
MC81_RS08525	COG2200	EAL domain
MC81_RS08525	COG2203	Gaf domain
MC81_RS08530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MC81_RS08535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS08560	COG1686	Belongs to the peptidase S11 family
MC81_RS08565	COG0488	(ABC) transporter
MC81_RS08580	COG0583	DNA-binding transcription factor activity
MC81_RS08595	COG0688	phosphatidylethanolamine metabolic process
MC81_RS08605	COG1408	metallophosphoesterase
MC81_RS08625	COG1464	Belongs to the NlpA lipoprotein family
MC81_RS08630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MC81_RS08635	COG0010	Belongs to the arginase family
MC81_RS08665	COG2363	Small membrane protein
MC81_RS08670	COG0697	spore germination
MC81_RS08680	COG2133	pyrroloquinoline quinone binding
MC81_RS08685	COG0625	glutathione transferase activity
MC81_RS08690	COG0583	DNA-binding transcription factor activity
MC81_RS08700	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MC81_RS08705	COG1794	racemase activity, acting on amino acids and derivatives
MC81_RS08725	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_RS08735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MC81_RS08745	COG1653	transport
MC81_RS08750	COG1175	transmembrane transport
MC81_RS08755	COG0395	ABC-type sugar transport system, permease component
MC81_RS08760	COG3842	ATPase activity
MC81_RS08775	COG2205	protein histidine kinase activity
MC81_RS08780	COG0745	RESPONSE REGULATOR receiver
MC81_RS08795	COG0783	Belongs to the Dps family
MC81_RS08800	COG0583	DNA-binding transcription factor activity
MC81_RS08805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MC81_RS08815	COG0583	DNA-binding transcription factor activity
MC81_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS08845	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS08850	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS08865	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_RS08875	COG3842	ATPase activity
MC81_RS08880	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS08885	COG1741	Belongs to the pirin family
MC81_RS08890	COG1741	Belongs to the pirin family
MC81_RS08895	COG0583	DNA-binding transcription factor activity
MC81_RS08900	COG2204	response regulator
MC81_RS08910	COG0174	glutamine synthetase
MC81_RS08915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MC81_RS08920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MC81_RS08935	COG1960	acyl-CoA dehydrogenase activity
MC81_RS08945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MC81_RS08950	COG1561	YicC-like family, N-terminal region
MC81_RS08955	COG0833	amino acid
MC81_RS08960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MC81_RS08965	COG0791	NLP P60 protein
MC81_RS08970	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS08975	COG2863	cytochrome
MC81_RS08980	COG3258	Cytochrome c
MC81_RS08985	COG0194	GDP metabolic process
MC81_RS08990	COG1758	RNA polymerase activity
MC81_RS08995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MC81_RS09000	COG1126	abc transporter atp-binding protein
MC81_RS09005	COG0765	amino acid transport
MC81_RS09010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS09050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_RS09080	COG4336	lyase activity
MC81_RS09085	COG0583	DNA-binding transcription factor activity
MC81_RS09115	COG0583	DNA-binding transcription factor activity
MC81_RS09125	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MC81_RS09130	COG0560	Phosphoserine phosphatase
MC81_RS09135	COG0583	DNA-binding transcription factor activity
MC81_RS09140	COG3842	ATPase activity
MC81_RS09145	COG1178	ABC-type Fe3 transport system permease component
MC81_RS09155	COG4181	ATPase activity
MC81_RS09165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_RS09175	COG0584	glycerophosphoryl diester phosphodiesterase
MC81_RS09180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MC81_RS09190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MC81_RS09190	COG0678	peroxiredoxin activity
MC81_RS09200	COG0789	Transcriptional regulator
MC81_RS09205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MC81_RS09230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MC81_RS09240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MC81_RS09245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MC81_RS09250	COG2252	PERMEase
MC81_RS09255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MC81_RS09260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_RS09295	COG0488	(ABC) transporter
MC81_RS09315	COG1619	proteins homologs of microcin C7 resistance protein MccF
MC81_RS09340	COG2212	antiporter activity
MC81_RS09345	COG1863	multisubunit Na H antiporter MnhE subunit
MC81_RS09350	COG0651	ATP synthesis coupled electron transport
MC81_RS09355	COG1006	Multisubunit Na H antiporter MnhC subunit
MC81_RS09360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MC81_RS09360	COG2111	Na H antiporter
MC81_RS09365	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS09380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS09390	COG1309	transcriptional regulator
MC81_RS09395	COG1960	acyl-CoA dehydrogenase activity
MC81_RS09410	COG0420	3'-5' exonuclease activity
MC81_RS09415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS09445	COG1960	acyl-CoA dehydrogenase activity
MC81_RS09450	COG3387	PFAM Glycoside hydrolase 15-related
MC81_RS09455	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS09460	COG2199	diguanylate cyclase activity
MC81_RS09460	COG2203	Gaf domain
MC81_RS09470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MC81_RS09480	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MC81_RS09485	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS09490	COG0583	DNA-binding transcription factor activity
MC81_RS09505	COG0395	ABC-type sugar transport system, permease component
MC81_RS09515	COG3842	ATPase activity
MC81_RS09520	COG3842	ATPase activity
MC81_RS09545	COG2130	NADP-dependent
MC81_RS09550	COG1309	transcriptional regulator
MC81_RS09560	COG1131	(ABC) transporter
MC81_RS09565	COG0842	Transport permease protein
MC81_RS09610	COG1902	pentaerythritol trinitrate reductase activity
MC81_RS09620	COG0154	amidase activity
MC81_RS09625	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS09630	COG0583	DNA-binding transcription factor activity
MC81_RS09645	COG0602	queuosine metabolic process
MC81_RS09650	COG0720	synthase
MC81_RS09670	COG1566	PFAM secretion protein HlyD family protein
MC81_RS09680	COG0400	carboxylic ester hydrolase activity
MC81_RS09685	COG0833	amino acid
MC81_RS09700	COG0587	DNA-directed DNA polymerase activity
MC81_RS09715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_RS09720	COG2271	Major facilitator Superfamily
MC81_RS09755	COG2267	carboxylic ester hydrolase activity
MC81_RS09810	COG2764	glyoxalase bleomycin resistance protein dioxygenase
MC81_RS09820	COG1473	amidohydrolase
MC81_RS09830	COG1802	Transcriptional regulator
MC81_RS09835	COG1414	Transcriptional regulator
MC81_RS09850	COG0667	Aldo Keto reductase
MC81_RS09860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MC81_RS09865	COG1802	Transcriptional regulator
MC81_RS09875	COG0601	transmembrane transport
MC81_RS09880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS09885	COG0444	Belongs to the ABC transporter superfamily
MC81_RS09890	COG4608	Belongs to the ABC transporter superfamily
MC81_RS09900	COG1309	transcriptional regulator
MC81_RS09915	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS09925	COG1683	Conserved Protein
MC81_RS09935	COG2207	Transcriptional regulator
MC81_RS09955	COG1360	Flagellar Motor Protein
MC81_RS09975	COG3795	YCII-related domain
MC81_RS09980	COG3795	YCII-related domain
MC81_RS09990	COG4941	Belongs to the sigma-70 factor family
MC81_RS10000	COG0697	spore germination
MC81_RS10005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC81_RS10025	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS10035	COG1846	Transcriptional regulator
MC81_RS10045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_RS10055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MC81_RS10075	COG0642	Histidine kinase
MC81_RS10085	COG2986	histidine ammonia-lyase
MC81_RS10105	COG0583	DNA-binding transcription factor activity
MC81_RS10120	COG2885	chlorophyll binding
MC81_RS10145	COG0625	glutathione transferase activity
MC81_RS10155	COG2733	membrane
MC81_RS10165	COG0583	DNA-binding transcription factor activity
MC81_RS10170	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS10170	COG1024	Enoyl-CoA hydratase
MC81_RS10175	COG0183	Belongs to the thiolase family
MC81_RS10180	COG1960	acyl-CoA dehydrogenase activity
MC81_RS10190	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS10200	COG3842	ATPase activity
MC81_RS10220	COG0583	DNA-binding transcription factor activity
MC81_RS10225	COG2814	Major facilitator Superfamily
MC81_RS10250	COG1522	sequence-specific DNA binding
MC81_RS10255	COG5001	Diguanylate cyclase
MC81_RS10255	COG2203	Gaf domain
MC81_RS10255	COG3706	GGDEF domain
MC81_RS10255	COG4251	negative regulation of phosphorylation
MC81_RS10260	COG2201	protein-glutamate methylesterase activity
MC81_RS10320	COG0667	Aldo Keto reductase
MC81_RS10325	COG1902	pentaerythritol trinitrate reductase activity
MC81_RS10330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MC81_RS10350	COG2814	Major facilitator Superfamily
MC81_RS10355	COG0583	DNA-binding transcription factor activity
MC81_RS10385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS10445	COG2814	Major facilitator Superfamily
MC81_RS10450	COG4221	oxidoreductase activity
MC81_RS10460	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
MC81_RS10475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS10480	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MC81_RS10505	COG0583	DNA-binding transcription factor activity
MC81_RS10525	COG0028	Belongs to the TPP enzyme family
MC81_RS10550	COG0702	epimerase
MC81_RS10560	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS10575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MC81_RS10575	COG0519	Catalyzes the synthesis of GMP from XMP
MC81_RS10635	COG4774	siderophore transport
MC81_RS10645	COG2072	flavoprotein involved in K transport
MC81_RS10650	COG0601	transmembrane transport
MC81_RS10655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS10660	COG0444	Belongs to the ABC transporter superfamily
MC81_RS10665	COG4608	Belongs to the ABC transporter superfamily
MC81_RS10670	COG0747	negative chemotaxis
MC81_RS10725	COG3712	iron ion homeostasis
MC81_RS10770	COG4692	amylo-alpha-1,6-glucosidase activity
MC81_RS10775	COG0583	DNA-binding transcription factor activity
MC81_RS10780	COG2271	Major facilitator Superfamily
MC81_RS10790	COG0129	dihydroxy-acid dehydratase activity
MC81_RS10795	COG2084	Dehydrogenase
MC81_RS10800	COG1335	isochorismatase
MC81_RS10805	COG4977	sequence-specific DNA binding
MC81_RS10830	COG1304	FMN binding
MC81_RS10845	COG0346	lactoylglutathione lyase activity
MC81_RS10855	COG0543	2 iron, 2 sulfur cluster binding
MC81_RS10855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_RS10885	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MC81_RS10975	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS10985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_RS11005	COG1595	DNA-templated transcription, initiation
MC81_RS11010	COG3712	iron ion homeostasis
MC81_RS11015	COG4774	siderophore transport
MC81_RS11020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MC81_RS11020	COG0047	phosphoribosylformylglycinamidine synthase activity
MC81_RS11030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_RS11030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MC81_RS11035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_RS11045	COG0613	PHP domain protein
MC81_RS11055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MC81_RS11065	COG0583	DNA-binding transcription factor activity
MC81_RS11070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MC81_RS11070	COG2146	nitrite reductase [NAD(P)H] activity
MC81_RS11075	COG2146	nitrite reductase [NAD(P)H] activity
MC81_RS11075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MC81_RS11090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MC81_RS11095	COG1126	abc transporter atp-binding protein
MC81_RS11100	COG0765	amino acid transport
MC81_RS11105	COG0765	amino acid transport
MC81_RS11110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS11125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_RS11130	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_RS11140	COG1850	ribulose-bisphosphate carboxylase activity
MC81_RS11175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS11180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS11205	COG2146	nitrite reductase [NAD(P)H] activity
MC81_RS11230	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC81_RS11240	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MC81_RS11245	COG4604	ABC transporter, ATP-binding protein
MC81_RS11250	COG4605	iron ion homeostasis
MC81_RS11255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC81_RS11260	COG4607	ABC-type enterochelin transport system periplasmic component
MC81_RS11265	COG4771	TonB-dependent receptor
MC81_RS11270	COG0745	RESPONSE REGULATOR receiver
MC81_RS11285	COG1136	(ABC) transporter
MC81_RS11300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MC81_RS11305	COG2271	Major facilitator Superfamily
MC81_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS11320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MC81_RS11330	COG1309	transcriptional regulator
MC81_RS11335	COG0183	Belongs to the thiolase family
MC81_RS11340	COG1022	Amp-dependent synthetase and ligase
MC81_RS11370	COG1024	Enoyl-CoA hydratase
MC81_RS11380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS11390	COG0583	DNA-binding transcription factor activity
MC81_RS11395	COG1803	Methylglyoxal synthase
MC81_RS11400	COG2975	iron-sulfur cluster assembly
MC81_RS11405	COG0633	Ferredoxin
MC81_RS11410	COG0443	Heat shock 70 kDa protein
MC81_RS11415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MC81_RS11425	COG0822	iron-sulfur transferase activity
MC81_RS11430	COG1104	cysteine desulfurase activity
MC81_RS11440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MC81_RS11445	COG0556	nucleotide-excision repair
MC81_RS11465	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS11470	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS11475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MC81_RS11480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MC81_RS11485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MC81_RS11490	COG0740	serine-type endopeptidase activity
MC81_RS11495	COG0544	peptidyl-prolyl cis-trans isomerase activity
MC81_RS11500	COG0501	Belongs to the peptidase M48B family
MC81_RS11510	COG1278	Cold shock
MC81_RS11520	COG1278	Cold shock
MC81_RS11545	COG0251	oxidation-reduction process
MC81_RS11555	COG0583	DNA-binding transcription factor activity
MC81_RS11570	COG1309	transcriptional regulator
MC81_RS11585	COG3008	intermembrane lipid transfer
MC81_RS11600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MC81_RS11605	COG3038	cytochrome b561
MC81_RS11750	COG1802	Transcriptional regulator
MC81_RS11750	COG4626	Terminase
MC81_RS11855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MC81_RS11880	COG2171	N-acyltransferase activity
MC81_RS11890	COG2890	protein-(glutamine-N5) methyltransferase activity
MC81_RS11895	COG0488	(ABC) transporter
MC81_RS11910	COG4771	TonB-dependent receptor
MC81_RS11925	COG0210	DNA helicase
MC81_RS11940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MC81_RS11940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MC81_RS11945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MC81_RS11950	COG0196	riboflavin kinase activity
MC81_RS11955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MC81_RS11960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MC81_RS11965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MC81_RS12010	COG0154	amidase activity
MC81_RS12050	COG0583	DNA-binding transcription factor activity
MC81_RS12065	COG1902	pentaerythritol trinitrate reductase activity
MC81_RS12070	COG1126	abc transporter atp-binding protein
MC81_RS12075	COG0765	amino acid transport
MC81_RS12080	COG0765	amino acid transport
MC81_RS12085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS12095	COG1764	response to oxidative stress
MC81_RS12100	COG1914	H( )-stimulated, divalent metal cation uptake system
MC81_RS12120	COG2271	Major facilitator Superfamily
MC81_RS12125	COG1802	Transcriptional regulator
MC81_RS12135	COG1024	Enoyl-CoA hydratase
MC81_RS12140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS12170	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MC81_RS12170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MC81_RS12170	COG0506	proline dehydrogenase activity
MC81_RS12180	COG3008	intermembrane lipid transfer
MC81_RS12185	COG2995	paraquat-inducible protein a
MC81_RS12190	COG0542	response to heat
MC81_RS12195	COG4953	penicillin-binding protein 1C
MC81_RS12200	COG2373	Large extracellular alpha-helical protein
MC81_RS12205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MC81_RS12210	COG1278	Cold shock
MC81_RS12220	COG0183	Belongs to the thiolase family
MC81_RS12225	COG0038	chloride channel
MC81_RS12235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MC81_RS12245	COG0811	peptide transport
MC81_RS12255	COG1663	tetraacyldisaccharide 4'-kinase activity
MC81_RS12260	COG2835	tetraacyldisaccharide 4'-kinase activity
MC81_RS12265	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MC81_RS12270	COG0563	adenylate kinase activity
MC81_RS12280	COG0728	peptidoglycan biosynthetic process
MC81_RS12290	COG0268	Binds directly to 16S ribosomal RNA
MC81_RS12295	COG0583	DNA-binding transcription factor activity
MC81_RS12325	COG2186	Transcriptional regulator
MC81_RS12335	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS12345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MC81_RS12375	COG3384	dioxygenase
MC81_RS12380	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS12395	COG3971	2-oxopent-4-enoate hydratase activity
MC81_RS12415	COG1234	tRNA 3'-trailer cleavage
MC81_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS12430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MC81_RS12440	COG1562	ergosterol biosynthetic process
MC81_RS12450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MC81_RS12475	COG1477	protein flavinylation
MC81_RS12490	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MC81_RS12505	COG5564	TIM-barrel signal transduction protein
MC81_RS12510	COG5441	Belongs to the UPF0261 family
MC81_RS12520	COG1802	Transcriptional regulator
MC81_RS12525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_RS12530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_RS12550	COG3119	arylsulfatase activity
MC81_RS12570	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS12575	COG3485	protocatechuate 3,4-dioxygenase
MC81_RS12585	COG0446	pyridine nucleotide-disulphide oxidoreductase
MC81_RS12595	COG0542	response to heat
MC81_RS12605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MC81_RS12615	COG0477	Major facilitator Superfamily
MC81_RS12645	COG0494	nUDIX hydrolase
MC81_RS12650	COG0443	Heat shock 70 kDa protein
MC81_RS12680	COG3530	Putative quorum-sensing-regulated virulence factor
MC81_RS12695	COG1595	DNA-templated transcription, initiation
MC81_RS12700	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MC81_RS12705	COG0625	glutathione transferase activity
MC81_RS12750	COG1522	sequence-specific DNA binding
MC81_RS12805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS12815	COG0519	Catalyzes the synthesis of GMP from XMP
MC81_RS12835	COG2951	lytic endotransglycosylase activity
MC81_RS12850	COG0583	DNA-binding transcription factor activity
MC81_RS12865	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS12875	COG0477	Major facilitator Superfamily
MC81_RS12880	COG1473	amidohydrolase
MC81_RS12885	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS12900	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
MC81_RS12920	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS12930	COG0023	Translation Initiation Factor
MC81_RS12940	COG2326	polyphosphate kinase activity
MC81_RS12955	COG2011	ABC-type metal ion transport system permease component
MC81_RS12960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MC81_RS12965	COG1464	Belongs to the NlpA lipoprotein family
MC81_RS12980	COG2814	Major facilitator Superfamily
MC81_RS12995	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS13020	COG1228	amidohydrolase
MC81_RS13035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MC81_RS13060	COG1566	PFAM secretion protein HlyD family protein
MC81_RS13100	COG0251	oxidation-reduction process
MC81_RS13140	COG2169	Transcriptional regulator
MC81_RS13165	COG1272	protein, Hemolysin III
MC81_RS13190	COG0789	Transcriptional regulator
MC81_RS13205	COG0842	Transport permease protein
MC81_RS13210	COG1131	(ABC) transporter
MC81_RS13220	COG4948	Mandelate Racemase Muconate Lactonizing
MC81_RS13230	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS13240	COG2824	Alkylphosphonate utilization operon protein PhnA
MC81_RS13255	COG0348	domain, Protein
MC81_RS13275	COG3278	Belongs to the heme-copper respiratory oxidase family
MC81_RS13295	COG0156	8-amino-7-oxononanoate synthase activity
MC81_RS13305	COG4106	trans-aconitate 2-methyltransferase activity
MC81_RS13305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MC81_RS13320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS13325	COG2301	Belongs to the HpcH HpaI aldolase family
MC81_RS13340	COG2224	Isocitrate lyase
MC81_RS13345	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MC81_RS13345	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MC81_RS13350	COG1858	cytochrome C peroxidase
MC81_RS13360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MC81_RS13375	COG0736	holo-[acyl-carrier-protein] synthase activity
MC81_RS13380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MC81_RS13390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_RS13395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_RS13420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MC81_RS13425	COG4149	molybdate abc transporter
MC81_RS13430	COG0725	ABC transporter, periplasmic molybdate-binding protein
MC81_RS13435	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MC81_RS13455	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MC81_RS13460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS13465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS13470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MC81_RS13475	COG4120	Belongs to the binding-protein-dependent transport system permease family
MC81_RS13485	COG0667	Aldo Keto reductase
MC81_RS13495	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS13500	COG1024	Enoyl-CoA hydratase
MC81_RS13510	COG1802	Transcriptional regulator
MC81_RS13525	COG1960	acyl-CoA dehydrogenase activity
MC81_RS13550	COG0183	Belongs to the thiolase family
MC81_RS13560	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS13565	COG1960	acyl-CoA dehydrogenase activity
MC81_RS13575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS13580	COG0583	DNA-binding transcription factor activity
MC81_RS13585	COG0517	IMP dehydrogenase activity
MC81_RS13585	COG0516	GMP reductase activity
MC81_RS13655	COG1802	Transcriptional regulator
MC81_RS13665	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS13670	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS13680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MC81_RS13685	COG3384	dioxygenase
MC81_RS13700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MC81_RS13760	COG4964	Belongs to the GSP D family
MC81_RS13805	COG1846	Transcriptional regulator
MC81_RS13810	COG4172	Belongs to the ABC transporter superfamily
MC81_RS13815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS13820	COG0601	transmembrane transport
MC81_RS13835	COG0598	Magnesium transport protein CorA
MC81_RS13855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MC81_RS13870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MC81_RS13875	COG1045	serine acetyltransferase
MC81_RS13880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MC81_RS13885	COG0166	Belongs to the GPI family
MC81_RS13930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC81_RS13950	COG0438	transferase activity, transferring glycosyl groups
MC81_RS13960	COG0110	maltose O-acetyltransferase activity
MC81_RS13965	COG0297	glycogen (starch) synthase activity
MC81_RS13970	COG2197	response regulator
MC81_RS13975	COG2197	response regulator
MC81_RS13985	COG1309	transcriptional regulator
MC81_RS13990	COG1960	acyl-CoA dehydrogenase activity
MC81_RS13995	COG0183	Belongs to the thiolase family
MC81_RS14000	COG1024	Enoyl-CoA hydratase
MC81_RS14000	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS14010	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS14010	COG1024	Enoyl-CoA hydratase
MC81_RS14015	COG0183	Belongs to the thiolase family
MC81_RS14030	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS14040	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS14050	COG4774	siderophore transport
MC81_RS14060	COG3395	kinase activity
MC81_RS14065	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MC81_RS14075	COG2186	Transcriptional regulator
MC81_RS14080	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC81_RS14090	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS14095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_RS14100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MC81_RS14105	COG1024	Enoyl-CoA hydratase
MC81_RS14115	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS14125	COG1414	Transcriptional regulator
MC81_RS14135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MC81_RS14200	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
MC81_RS14210	COG0527	aspartate kinase activity
MC81_RS14215	COG0037	tRNA processing
MC81_RS14220	COG0825	malonyl-CoA metabolic process
MC81_RS14230	COG0215	cysteine-tRNA ligase activity
MC81_RS14245	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MC81_RS14250	COG1968	undecaprenyl-diphosphatase activity
MC81_RS14255	COG1253	flavin adenine dinucleotide binding
MC81_RS14265	COG0483	inositol monophosphate 1-phosphatase activity
MC81_RS14285	COG0668	transmembrane transport
MC81_RS14315	COG0235	Class ii aldolase
MC81_RS14325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_RS14345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MC81_RS14350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS14370	COG1802	Transcriptional regulator
MC81_RS14390	COG3360	Dodecin
MC81_RS14400	COG0583	DNA-binding transcription factor activity
MC81_RS14405	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS14430	COG0583	DNA-binding transcription factor activity
MC81_RS14435	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS14465	COG2850	peptidyl-arginine hydroxylation
MC81_RS14475	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MC81_RS14480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_RS14485	COG1994	Peptidase M50
MC81_RS14490	COG0009	L-threonylcarbamoyladenylate synthase
MC81_RS14495	COG2321	neutral zinc metallopeptidase
MC81_RS14515	COG0640	Transcriptional regulator
MC81_RS14545	COG0583	DNA-binding transcription factor activity
MC81_RS14550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_RS14560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_RS14570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_RS14580	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS14590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MC81_RS14600	COG0784	Response regulator, receiver
MC81_RS14600	COG4191	Histidine kinase
MC81_RS14605	COG2204	response regulator
MC81_RS14625	COG0583	DNA-binding transcription factor activity
MC81_RS14640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC81_RS14650	COG1024	Enoyl-CoA hydratase
MC81_RS14680	COG1960	acyl-CoA dehydrogenase activity
MC81_RS14685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_RS14695	COG0183	Belongs to the thiolase family
MC81_RS14725	COG1802	Transcriptional regulator
MC81_RS14775	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS14795	COG0028	Belongs to the TPP enzyme family
MC81_RS14820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS14835	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS14850	COG1058	Belongs to the CinA family
MC81_RS14850	COG1546	Belongs to the CinA family
MC81_RS14870	COG0668	transmembrane transport
MC81_RS14875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MC81_RS14880	COG0166	Belongs to the GPI family
MC81_RS14910	COG0438	transferase activity, transferring glycosyl groups
MC81_RS14925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_RS14965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS14970	COG0765	amino acid transport
MC81_RS14990	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS15010	COG1396	sequence-specific DNA binding
MC81_RS15025	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS15035	COG3781	membrane
MC81_RS15040	COG0243	molybdopterin cofactor binding
MC81_RS15045	COG0583	DNA-binding transcription factor activity
MC81_RS15055	COG4175	Glycine betaine
MC81_RS15055	COG3448	diguanylate cyclase activity
MC81_RS15060	COG4176	ABC-type proline glycine betaine transport system permease component
MC81_RS15070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MC81_RS15075	COG2814	Major facilitator Superfamily
MC81_RS15080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MC81_RS15085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MC81_RS15120	COG1686	Belongs to the peptidase S11 family
MC81_RS15130	COG1846	Transcriptional regulator
MC81_RS15135	COG2814	Major facilitator Superfamily
MC81_RS15140	COG0495	leucyl-tRNA aminoacylation
MC81_RS15155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MC81_RS15175	COG0154	amidase activity
MC81_RS15185	COG0477	Major facilitator Superfamily
MC81_RS15195	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS15210	COG0583	DNA-binding transcription factor activity
MC81_RS15245	COG0583	DNA-binding transcription factor activity
MC81_RS15250	COG0427	acetyl-CoA hydrolase
MC81_RS15255	COG0583	DNA-binding transcription factor activity
MC81_RS15260	COG3264	Mechanosensitive ion channel
MC81_RS15260	COG1511	domain protein
MC81_RS15315	COG3842	ATPase activity
MC81_RS15320	COG1176	ABC-type spermidine putrescine transport system, permease component I
MC81_RS15325	COG1177	transmembrane transport
MC81_RS15330	COG3938	Belongs to the proline racemase family
MC81_RS15340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MC81_RS15345	COG3958	Transketolase
MC81_RS15350	COG3959	Transketolase, thiamine diphosphate binding domain
MC81_RS15355	COG1802	Transcriptional regulator
MC81_RS15360	COG0371	Dehydrogenase
MC81_RS15365	COG3246	L-lysine catabolic process to acetate
MC81_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS15385	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_RS15400	COG0604	alcohol dehydrogenase
MC81_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS15400	COG3321	synthase
MC81_RS15405	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS15410	COG0500	methyltransferase
MC81_RS15420	COG0667	Aldo Keto reductase
MC81_RS15430	COG2207	Transcriptional regulator
MC81_RS15440	COG0765	amino acid transport
MC81_RS15460	COG0251	oxidation-reduction process
MC81_RS15470	COG1609	Transcriptional regulator
MC81_RS15480	COG0583	DNA-binding transcription factor activity
MC81_RS15490	COG1335	isochorismatase
MC81_RS15520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_RS15535	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_RS15540	COG0683	leucine binding
MC81_RS15565	COG1024	Enoyl-CoA hydratase
MC81_RS15570	COG0022	dehydrogenase e1 component
MC81_RS15575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MC81_RS15605	COG1024	Enoyl-CoA hydratase
MC81_RS15620	COG1960	acyl-CoA dehydrogenase activity
MC81_RS15625	COG1024	Enoyl-CoA hydratase
MC81_RS15645	COG2030	dehydratase
MC81_RS15650	COG1960	acyl-CoA dehydrogenase activity
MC81_RS15665	COG1278	Cold shock
MC81_RS15680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MC81_RS15715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MC81_RS15725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MC81_RS15730	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MC81_RS15735	COG1534	Rna-binding protein
MC81_RS15740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MC81_RS15745	COG0840	transmembrane signaling receptor activity
MC81_RS15750	COG2233	PERMEase
MC81_RS15770	COG3842	ATPase activity
MC81_RS15775	COG0583	DNA-binding transcription factor activity
MC81_RS15780	COG0406	alpha-ribazole phosphatase activity
MC81_RS15790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MC81_RS15795	COG0505	Belongs to the CarA family
MC81_RS15800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MC81_RS15805	COG0583	DNA-binding transcription factor activity
MC81_RS15810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MC81_RS15825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS15835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MC81_RS15840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS15855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MC81_RS15870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS15885	COG1177	transmembrane transport
MC81_RS15895	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_RS15900	COG3842	ATPase activity
MC81_RS15910	COG1074	ATP-dependent DNA helicase activity
MC81_RS15935	COG1686	Belongs to the peptidase S11 family
MC81_RS15950	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MC81_RS15955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MC81_RS15960	COG4974	Belongs to the 'phage' integrase family
MC81_RS15965	COG0583	DNA-binding transcription factor activity
MC81_RS15970	COG0028	Belongs to the TPP enzyme family
MC81_RS15975	COG1960	acyl-CoA dehydrogenase activity
MC81_RS15990	COG0583	DNA-binding transcription factor activity
MC81_RS15995	COG2814	Major facilitator Superfamily
MC81_RS16000	COG2030	dehydratase
MC81_RS16020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MC81_RS16065	COG0028	Belongs to the TPP enzyme family
MC81_RS16070	COG1126	abc transporter atp-binding protein
MC81_RS16075	COG0765	amino acid transport
MC81_RS16080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS16090	COG1414	Transcriptional regulator
MC81_RS16095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS16100	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS16110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_RS16115	COG1414	Transcriptional regulator
MC81_RS16120	COG0009	L-threonylcarbamoyladenylate synthase
MC81_RS16125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MC81_RS16130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MC81_RS16135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MC81_RS16140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MC81_RS16160	COG1301	dicarboxylic acid transport
MC81_RS16180	COG3454	Phosphonate metabolism
MC81_RS16185	COG4778	phosphonate C-P lyase system protein PhnL
MC81_RS16190	COG4107	phosphonate C-P lyase system protein PhnK
MC81_RS16195	COG3627	carbon phosphorus lyase activity
MC81_RS16200	COG3626	phosphonate metabolism
MC81_RS16210	COG3624	Phosphonate C-P lyase system protein PhnG
MC81_RS16215	COG2188	Transcriptional regulator
MC81_RS16220	COG3454	Phosphonate metabolism
MC81_RS16225	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MC81_RS16230	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MC81_RS16235	COG0583	DNA-binding transcription factor activity
MC81_RS16240	COG0405	Gamma-glutamyltransferase
MC81_RS16255	COG3639	organic phosphonate transmembrane transporter activity
MC81_RS16260	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MC81_RS16265	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MC81_RS16285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MC81_RS16295	COG0739	heme binding
MC81_RS16305	COG0521	Mo-molybdopterin cofactor biosynthetic process
MC81_RS16315	COG0306	phosphate transporter
MC81_RS16355	COG0625	glutathione transferase activity
MC81_RS16375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MC81_RS16380	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MC81_RS16395	COG0126	phosphoglycerate kinase activity
MC81_RS16400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MC81_RS16405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MC81_RS16410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MC81_RS16415	COG2732	(Barnase) inhibitor
MC81_RS16425	COG0280	phosphate acetyltransferase
MC81_RS16425	COG0281	malic enzyme
MC81_RS16435	COG0436	Aminotransferase
MC81_RS16440	COG0741	lytic transglycosylase activity
MC81_RS16445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MC81_RS16460	COG4575	ribosome binding
MC81_RS16470	COG0243	molybdopterin cofactor binding
MC81_RS16475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MC81_RS16480	COG1116	anion transmembrane transporter activity
MC81_RS16485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS16490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MC81_RS16505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MC81_RS16510	COG2027	D-alanyl-D-alanine carboxypeptidase
MC81_RS16525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MC81_RS16530	COG0343	queuine tRNA-ribosyltransferase activity
MC81_RS16535	COG1862	Preprotein translocase
MC81_RS16540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MC81_RS16545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MC81_RS16550	COG0640	Transcriptional regulator
MC81_RS16560	COG0740	serine-type endopeptidase activity
MC81_RS16570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MC81_RS16580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MC81_RS16585	COG1702	phosphate starvation-inducible protein PhoH
MC81_RS16590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MC81_RS16595	COG4535	Mg2 and Co2 transporter CorC
MC81_RS16600	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MC81_RS16605	COG0667	Aldo Keto reductase
MC81_RS16650	COG0697	spore germination
MC81_RS16660	COG0678	peroxiredoxin activity
MC81_RS16670	COG0412	Dienelactone hydrolase
MC81_RS16680	COG0315	cyclic pyranopterin monophosphate synthase activity
MC81_RS16695	COG0521	Mo-molybdopterin cofactor biosynthetic process
MC81_RS16700	COG0303	'Molybdopterin
MC81_RS16705	COG0746	molybdenum cofactor guanylyltransferase activity
MC81_RS16710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MC81_RS16720	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MC81_RS16730	COG3383	formate dehydrogenase (NAD+) activity
MC81_RS16735	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MC81_RS16765	COG0583	DNA-binding transcription factor activity
MC81_RS16770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MC81_RS16805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_RS16815	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS16830	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS16840	COG2188	Transcriptional regulator
MC81_RS16845	COG0683	leucine binding
MC81_RS16885	COG0251	oxidation-reduction process
MC81_RS16890	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS16905	COG0456	acetyltransferase
MC81_RS16985	COG0671	phosphoesterase, PA-phosphatase related
MC81_RS17010	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MC81_RS17020	COG1666	GTP binding
MC81_RS17025	COG1120	ATPase activity
MC81_RS17030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC81_RS17035	COG4558	Periplasmic binding protein
MC81_RS17040	COG3720	iron ion transport
MC81_RS17055	COG1595	DNA-templated transcription, initiation
MC81_RS17085	COG2378	regulation of single-species biofilm formation
MC81_RS17095	COG1113	amino acid transport
MC81_RS17105	COG1522	sequence-specific DNA binding
MC81_RS17110	COG1272	protein, Hemolysin III
MC81_RS17115	COG3191	aminopeptidase activity
MC81_RS17120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS17125	COG0765	amino acid transport
MC81_RS17130	COG1126	abc transporter atp-binding protein
MC81_RS17145	COG1999	signal sequence binding
MC81_RS17165	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MC81_RS17175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MC81_RS17180	COG1845	cytochrome c oxidase, subunit III
MC81_RS17195	COG4772	TonB-dependent receptor
MC81_RS17215	COG0280	phosphate acetyltransferase
MC81_RS17215	COG0281	malic enzyme
MC81_RS17240	COG0697	spore germination
MC81_RS17280	COG0456	acetyltransferase
MC81_RS17285	COG1396	sequence-specific DNA binding
MC81_RS17290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC81_RS17300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MC81_RS17315	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS17320	COG1285	pathogenesis
MC81_RS17325	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS17330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC81_RS17350	COG3712	iron ion homeostasis
MC81_RS17355	COG1595	DNA-templated transcription, initiation
MC81_RS17365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MC81_RS17370	COG0330	HflC and HflK could
MC81_RS17385	COG2807	transmembrane transport
MC81_RS17390	COG2207	Transcriptional regulator
MC81_RS17415	COG4106	trans-aconitate 2-methyltransferase activity
MC81_RS17420	COG0861	Integral membrane protein TerC family
MC81_RS17425	COG0583	DNA-binding transcription factor activity
MC81_RS17460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MC81_RS17465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS17470	COG0477	Major facilitator Superfamily
MC81_RS17475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MC81_RS17480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MC81_RS17485	COG1845	cytochrome c oxidase, subunit III
MC81_RS17490	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MC81_RS17500	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_RS17510	COG0625	glutathione transferase activity
MC81_RS17540	COG0519	Catalyzes the synthesis of GMP from XMP
MC81_RS17560	COG3795	YCII-related domain
MC81_RS17565	COG0667	Aldo Keto reductase
MC81_RS17580	COG2837	iron assimilation
MC81_RS17600	COG2188	Transcriptional regulator
MC81_RS17625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS17630	COG1024	Enoyl-CoA hydratase
MC81_RS17640	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS17655	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS17660	COG2030	dehydratase
MC81_RS17670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_RS17675	COG1960	acyl-CoA dehydrogenase activity
MC81_RS17680	COG1960	acyl-CoA dehydrogenase activity
MC81_RS17690	COG1280	lysine exporter protein (LysE YggA)
MC81_RS17730	COG0133	tryptophan synthase activity
MC81_RS17755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MC81_RS17780	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MC81_RS17785	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MC81_RS17790	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MC81_RS17795	COG4774	siderophore transport
MC81_RS17800	COG4607	ABC-type enterochelin transport system periplasmic component
MC81_RS17805	COG4604	ABC transporter, ATP-binding protein
MC81_RS17810	COG4605	iron ion homeostasis
MC81_RS17815	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC81_RS17825	COG1132	(ABC) transporter
MC81_RS17825	COG2375	cellular response to nickel ion
MC81_RS17860	COG0747	negative chemotaxis
MC81_RS17865	COG0601	transmembrane transport
MC81_RS17870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS17875	COG0444	Belongs to the ABC transporter superfamily
MC81_RS17880	COG4608	Belongs to the ABC transporter superfamily
MC81_RS17885	COG0154	amidase activity
MC81_RS17895	COG2301	Belongs to the HpcH HpaI aldolase family
MC81_RS17910	COG3246	L-lysine catabolic process to acetate
MC81_RS17920	COG2030	dehydratase
MC81_RS17925	COG2130	NADP-dependent
MC81_RS17940	COG0625	glutathione transferase activity
MC81_RS17975	COG2030	dehydratase
MC81_RS17975	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS17980	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS17990	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS17995	COG1454	alcohol dehydrogenase
MC81_RS18015	COG1960	acyl-CoA dehydrogenase activity
MC81_RS18030	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS18035	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC81_RS18040	COG1802	Transcriptional regulator
MC81_RS18045	COG2249	NAD(P)H dehydrogenase (quinone) activity
MC81_RS18075	COG0668	transmembrane transport
MC81_RS18085	COG1733	regulation of RNA biosynthetic process
MC81_RS18110	COG4774	siderophore transport
MC81_RS18155	COG1301	dicarboxylic acid transport
MC81_RS18160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS18235	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS18240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_RS18245	COG0626	cystathionine gamma-synthase activity
MC81_RS18250	COG1522	sequence-specific DNA binding
MC81_RS18255	COG0583	DNA-binding transcription factor activity
MC81_RS18260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS18280	COG1309	transcriptional regulator
MC81_RS18290	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS18295	COG0596	Alpha beta hydrolase
MC81_RS18300	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS18310	COG0247	lactate metabolic process
MC81_RS18320	COG1802	Transcriptional regulator
MC81_RS18325	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS18355	COG1024	Enoyl-CoA hydratase
MC81_RS18365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS18375	COG0444	Belongs to the ABC transporter superfamily
MC81_RS18380	COG4608	Belongs to the ABC transporter superfamily
MC81_RS18395	COG1024	Enoyl-CoA hydratase
MC81_RS18405	COG1595	DNA-templated transcription, initiation
MC81_RS18445	COG0583	DNA-binding transcription factor activity
MC81_RS18465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_RS18470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_RS18495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MC81_RS18505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS18520	COG0583	DNA-binding transcription factor activity
MC81_RS18525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MC81_RS18535	COG0693	protein deglycase activity
MC81_RS18545	COG0500	methyltransferase
MC81_RS18565	COG0697	spore germination
MC81_RS18575	COG1304	FMN binding
MC81_RS18580	COG2084	Dehydrogenase
MC81_RS18600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS18605	COG3618	amidohydrolase
MC81_RS18610	COG0583	DNA-binding transcription factor activity
MC81_RS18635	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MC81_RS18640	COG0459	protein refolding
MC81_RS18650	COG1846	Transcriptional regulator
MC81_RS18670	COG1917	Cupin 2, conserved barrel domain protein
MC81_RS18680	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MC81_RS18685	COG0246	Mannitol dehydrogenase
MC81_RS18690	COG4948	Mandelate Racemase Muconate Lactonizing
MC81_RS18695	COG2721	sulfolactate sulfo-lyase activity
MC81_RS18705	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS18710	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_RS18720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_RS18725	COG1063	alcohol dehydrogenase
MC81_RS18735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MC81_RS18740	COG1252	NADH dehydrogenase
MC81_RS18745	COG0284	orotidine-5'-phosphate decarboxylase activity
MC81_RS18750	COG1546	Belongs to the CinA family
MC81_RS18755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MC81_RS18765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MC81_RS18770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MC81_RS18795	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MC81_RS18800	COG3639	organic phosphonate transmembrane transporter activity
MC81_RS18805	COG3639	organic phosphonate transmembrane transporter activity
MC81_RS18845	COG0742	ribosomal rna small subunit methyltransferase
MC81_RS18850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MC81_RS18855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC81_RS18860	COG3135	benzoate transporter
MC81_RS18875	COG2814	Major facilitator Superfamily
MC81_RS18890	COG0473	3-isopropylmalate dehydrogenase activity
MC81_RS18890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_RS18895	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS18900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_RS18910	COG0012	GTP binding
MC81_RS18940	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MC81_RS18955	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MC81_RS18990	COG0204	Acyl-transferase
MC81_RS18995	COG1368	sulfuric ester hydrolase activity
MC81_RS19000	COG2186	Transcriptional regulator
MC81_RS19010	COG0642	Histidine kinase
MC81_RS19015	COG0745	RESPONSE REGULATOR receiver
MC81_RS19020	COG0277	FAD linked oxidase domain protein
MC81_RS19035	COG0166	Belongs to the GPI family
MC81_RS19040	COG0438	transferase activity, transferring glycosyl groups
MC81_RS19045	COG0438	transferase activity, transferring glycosyl groups
MC81_RS19050	COG0438	transferase activity, transferring glycosyl groups
MC81_RS19060	COG0438	transferase activity, transferring glycosyl groups
MC81_RS19075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MC81_RS19080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MC81_RS19085	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MC81_RS19110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS19115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MC81_RS19135	COG0601	transmembrane transport
MC81_RS19140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS19145	COG4172	Belongs to the ABC transporter superfamily
MC81_RS19150	COG0154	amidase activity
MC81_RS19165	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MC81_RS19165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MC81_RS19170	COG0509	glycine decarboxylation via glycine cleavage system
MC81_RS19175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MC81_RS19190	COG2081	HI0933 family
MC81_RS19210	COG2199	diguanylate cyclase activity
MC81_RS19220	COG0717	Belongs to the dCTP deaminase family
MC81_RS19235	COG0489	protein tyrosine kinase activity
MC81_RS19245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MC81_RS19245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MC81_RS19250	COG1054	Belongs to the UPF0176 family
MC81_RS19265	COG2755	lipolytic protein G-D-S-L family
MC81_RS19265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MC81_RS19280	COG0745	RESPONSE REGULATOR receiver
MC81_RS19285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MC81_RS19290	COG2200	EAL domain
MC81_RS19305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_RS19310	COG0842	Transport permease protein
MC81_RS19310	COG1129	ABC transporter
MC81_RS19315	COG0842	Transport permease protein
MC81_RS19335	COG0697	spore germination
MC81_RS19340	COG1271	oxidase subunit
MC81_RS19345	COG1294	oxidase, subunit
MC81_RS19355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS19370	COG3976	FMN-binding domain protein
MC81_RS19370	COG1053	succinate dehydrogenase
MC81_RS19375	COG0583	DNA-binding transcription factor activity
MC81_RS19380	COG0625	glutathione transferase activity
MC81_RS19585	COG0583	DNA-binding transcription factor activity
MC81_RS19595	COG2267	carboxylic ester hydrolase activity
MC81_RS19605	COG3284	Transcriptional regulator
MC81_RS19620	COG3210	domain, Protein
MC81_RS19700	COG2132	Multicopper oxidase
MC81_RS19710	COG4133	protoheme IX ABC transporter activity
MC81_RS19715	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MC81_RS19740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_RS19745	COG3088	subunit of a heme lyase
MC81_RS19750	COG4235	cytochrome complex assembly
MC81_RS19755	COG0785	Cytochrome C biogenesis protein
MC81_RS19765	COG0165	Argininosuccinate lyase
MC81_RS19770	COG0583	DNA-binding transcription factor activity
MC81_RS19785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MC81_RS19790	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS19795	COG2072	flavoprotein involved in K transport
MC81_RS19805	COG3135	benzoate transporter
MC81_RS19820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MC81_RS19825	COG0583	DNA-binding transcription factor activity
MC81_RS19835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_RS19850	COG1802	Transcriptional regulator
MC81_RS19860	COG0477	Major facilitator Superfamily
MC81_RS19870	COG0505	Belongs to the CarA family
MC81_RS19915	COG0006	proline dipeptidase activity
MC81_RS19920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS19925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MC81_RS19930	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_RS19940	COG1522	sequence-specific DNA binding
MC81_RS19945	COG3275	phosphorelay sensor kinase activity
MC81_RS20010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MC81_RS20035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MC81_RS20045	COG0583	DNA-binding transcription factor activity
MC81_RS20050	COG2828	Protein conserved in bacteria
MC81_RS20105	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS20110	COG2207	Transcriptional regulator
MC81_RS20115	COG0459	protein refolding
MC81_RS20165	COG1295	ribonuclease BN
MC81_RS20175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MC81_RS20195	COG1652	LysM domain
MC81_RS20200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MC81_RS20205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MC81_RS20220	COG0625	glutathione transferase activity
MC81_RS20225	COG1414	Transcriptional regulator
MC81_RS20230	COG3734	2-keto-3-deoxy-galactonokinase
MC81_RS20235	COG0800	Aldolase
MC81_RS20240	COG4948	Mandelate Racemase Muconate Lactonizing
MC81_RS20245	COG2271	Major facilitator Superfamily
MC81_RS20250	COG1473	amidohydrolase
MC81_RS20260	COG2814	Major facilitator Superfamily
MC81_RS20290	COG0604	alcohol dehydrogenase
MC81_RS20300	COG0326	Molecular chaperone. Has ATPase activity
MC81_RS20310	COG2233	PERMEase
MC81_RS20380	COG0582	viral genome integration into host DNA
MC81_RS20430	COG1074	ATP-dependent DNA helicase activity
MC81_RS20435	COG3596	GTP binding
MC81_RS20540	COG4221	oxidoreductase activity
MC81_RS20570	COG1846	Transcriptional regulator
MC81_RS20575	COG0477	Major facilitator Superfamily
MC81_RS20580	COG2010	Cytochrome c
MC81_RS20580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MC81_RS20585	COG2080	2 iron, 2 sulfur cluster binding
MC81_RS20595	COG0596	Alpha beta hydrolase
MC81_RS20600	COG2309	aminopeptidase activity
MC81_RS20605	COG1335	isochorismatase
MC81_RS20610	COG2010	Cytochrome c
MC81_RS20610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MC81_RS20615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS20635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_RS20640	COG0583	DNA-binding transcription factor activity
MC81_RS20650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_RS20665	COG1172	Belongs to the binding-protein-dependent transport system permease family
MC81_RS20670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MC81_RS20675	COG3246	L-lysine catabolic process to acetate
MC81_RS20685	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS20690	COG0583	DNA-binding transcription factor activity
MC81_RS20735	COG0583	DNA-binding transcription factor activity
MC81_RS20745	COG1695	Transcriptional regulator
MC81_RS20760	COG0477	Major facilitator Superfamily
MC81_RS20770	COG0628	permease
MC81_RS20775	COG0583	DNA-binding transcription factor activity
MC81_RS20780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_RS20815	COG0625	glutathione transferase activity
MC81_RS20820	COG0077	Prephenate dehydratase
MC81_RS20820	COG1605	Chorismate mutase
MC81_RS20825	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS20830	COG2081	HI0933 family
MC81_RS20835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_RS20850	COG4177	L-phenylalanine transmembrane transporter activity
MC81_RS20855	COG1129	ABC transporter
MC81_RS20875	COG1126	abc transporter atp-binding protein
MC81_RS20880	COG0765	amino acid transport
MC81_RS20885	COG4597	amino acid ABC transporter
MC81_RS20890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS20895	COG2884	Cell division ATP-binding protein ftsE
MC81_RS20900	COG2177	Part of the ABC transporter FtsEX involved in
MC81_RS20915	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MC81_RS20925	COG2186	Transcriptional regulator
MC81_RS20935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MC81_RS20965	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS20970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MC81_RS20980	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_RS20985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_RS20990	COG0583	DNA-binding transcription factor activity
MC81_RS21000	COG1194	a g-specific adenine glycosylase
MC81_RS21015	COG0028	Belongs to the TPP enzyme family
MC81_RS21020	COG1802	Transcriptional regulator
MC81_RS21030	COG2226	methyltransferase
MC81_RS21050	COG0288	reversible hydration of carbon dioxide
MC81_RS21055	COG1802	Transcriptional regulator
MC81_RS21060	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS21090	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS21095	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS21100	COG1053	succinate dehydrogenase
MC81_RS21105	COG0625	glutathione transferase activity
MC81_RS21120	COG0583	DNA-binding transcription factor activity
MC81_RS21160	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS21180	COG4771	TonB-dependent receptor
MC81_RS21185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MC81_RS21190	COG2022	thiamine diphosphate biosynthetic process
MC81_RS21195	COG0351	phosphomethylpyrimidine kinase
MC81_RS21200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MC81_RS21210	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MC81_RS21220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MC81_RS21235	COG2226	methyltransferase
MC81_RS21240	COG0745	RESPONSE REGULATOR receiver
MC81_RS21245	COG5002	protein histidine kinase activity
MC81_RS21265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_RS21270	COG0583	DNA-binding transcription factor activity
MC81_RS21280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MC81_RS21285	COG1984	allophanate hydrolase subunit 2
MC81_RS21295	COG1802	Transcriptional regulator
MC81_RS21300	COG2860	membrane
MC81_RS21310	COG2223	nitrite transmembrane transporter activity
MC81_RS21315	COG2813	Specifically methylates the guanine in position
MC81_RS21315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_RS21320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_RS21325	COG2188	Transcriptional regulator
MC81_RS21330	COG2721	sulfolactate sulfo-lyase activity
MC81_RS21335	COG2721	sulfolactate sulfo-lyase activity
MC81_RS21345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_RS21350	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MC81_RS21375	COG2918	glutathione biosynthetic process
MC81_RS21395	COG0583	DNA-binding transcription factor activity
MC81_RS21405	COG1802	Transcriptional regulator
MC81_RS21435	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC81_RS21495	COG1595	DNA-templated transcription, initiation
MC81_RS21505	COG0583	DNA-binding transcription factor activity
MC81_RS21510	COG1764	response to oxidative stress
MC81_RS21550	COG2197	response regulator
MC81_RS21555	COG0784	Response regulator, receiver
MC81_RS21555	COG2205	protein histidine kinase activity
MC81_RS21570	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS21575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS21585	COG1309	transcriptional regulator
MC81_RS21595	COG1024	Enoyl-CoA hydratase
MC81_RS21600	COG1024	Enoyl-CoA hydratase
MC81_RS21605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MC81_RS21615	COG0747	negative chemotaxis
MC81_RS21620	COG0583	DNA-binding transcription factor activity
MC81_RS21625	COG2988	succinylglutamate desuccinylase activity
MC81_RS21630	COG4166	transmembrane transport
MC81_RS21635	COG0601	transmembrane transport
MC81_RS21645	COG0444	Belongs to the ABC transporter superfamily
MC81_RS21650	COG4608	Belongs to the ABC transporter superfamily
MC81_RS21660	COG2195	Cleaves the N-terminal amino acid of tripeptides
MC81_RS21670	COG2171	N-acyltransferase activity
MC81_RS21680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MC81_RS21685	COG0210	DNA helicase
MC81_RS21690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MC81_RS21695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MC81_RS21705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MC81_RS21715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MC81_RS21720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MC81_RS21725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MC81_RS21740	COG0356	it plays a direct role in the translocation of protons across the membrane
MC81_RS21755	COG1024	Enoyl-CoA hydratase
MC81_RS21770	COG3473	Maleate cis-trans isomerase
MC81_RS21795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC81_RS21815	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_RS21820	COG0683	leucine binding
MC81_RS21825	COG0583	DNA-binding transcription factor activity
MC81_RS21830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_RS21840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_RS21865	COG0037	tRNA processing
MC81_RS21870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_RS21880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_RS21885	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MC81_RS21890	COG2967	ApaG domain
MC81_RS21895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MC81_RS21900	COG0546	phosphoglycolate phosphatase activity
MC81_RS21910	COG0512	Glutamine amidotransferase of anthranilate synthase
MC81_RS21920	COG0134	indole-3-glycerol-phosphate synthase activity
MC81_RS21940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS21945	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS21945	COG1024	Enoyl-CoA hydratase
MC81_RS21965	COG3284	Transcriptional regulator
MC81_RS21970	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS21995	COG0709	Synthesizes selenophosphate from selenide and ATP
MC81_RS22000	COG1305	Transglutaminase-like
MC81_RS22015	COG3276	selenocysteine insertion sequence binding
MC81_RS22030	COG2864	formate dehydrogenase
MC81_RS22035	COG0437	4 iron, 4 sulfur cluster binding
MC81_RS22040	COG3383	formate dehydrogenase (NAD+) activity
MC81_RS22040	COG0243	molybdopterin cofactor binding
MC81_RS22045	COG3383	formate dehydrogenase (NAD+) activity
MC81_RS22045	COG0243	molybdopterin cofactor binding
MC81_RS22055	COG1607	acyl-coa hydrolase
MC81_RS22080	COG3064	Membrane
MC81_RS22085	COG3585	molybdate ion transport
MC81_RS22090	COG1116	anion transmembrane transporter activity
MC81_RS22095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS22100	COG0431	NADPH-dependent FMN reductase
MC81_RS22110	COG0543	2 iron, 2 sulfur cluster binding
MC81_RS22110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_RS22125	COG3069	C4-dicarboxylate transmembrane transporter activity
MC81_RS22135	COG1802	Transcriptional regulator
MC81_RS22185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MC81_RS22190	COG1473	amidohydrolase
MC81_RS22195	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS22200	COG0583	DNA-binding transcription factor activity
MC81_RS22205	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS22210	COG2814	Major facilitator Superfamily
MC81_RS22225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MC81_RS22255	COG0737	Belongs to the 5'-nucleotidase family
MC81_RS22260	COG0438	transferase activity, transferring glycosyl groups
MC81_RS22270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MC81_RS22275	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MC81_RS22285	COG2423	ornithine cyclodeaminase activity
MC81_RS22290	COG1522	sequence-specific DNA binding
MC81_RS22300	COG2423	ornithine cyclodeaminase activity
MC81_RS22310	COG0656	L-ascorbic acid biosynthetic process
MC81_RS22320	COG1956	GAF domain-containing protein
MC81_RS22360	COG0861	Integral membrane protein TerC family
MC81_RS22370	COG3246	L-lysine catabolic process to acetate
MC81_RS22385	COG2814	Major facilitator Superfamily
MC81_RS22395	COG3550	peptidyl-serine autophosphorylation
MC81_RS22405	COG3866	Pectate lyase
MC81_RS22410	COG4783	chaperone-mediated protein folding
MC81_RS22410	COG1560	Kdo2-lipid A biosynthetic process
MC81_RS22435	COG0438	transferase activity, transferring glycosyl groups
MC81_RS22440	COG0457	Tetratricopeptide repeat
MC81_RS22455	COG1522	sequence-specific DNA binding
MC81_RS22470	COG2814	Major facilitator Superfamily
MC81_RS22475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MC81_RS22495	COG1999	signal sequence binding
MC81_RS22505	COG1612	heme a metabolic process
MC81_RS22535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MC81_RS22555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MC81_RS22580	COG0069	glutamate synthase activity
MC81_RS22580	COG0070	glutamate synthase
MC81_RS22580	COG0067	glutamate synthase
MC81_RS22595	COG0583	DNA-binding transcription factor activity
MC81_RS22600	COG0477	Major facilitator Superfamily
MC81_RS22610	COG2070	2-Nitropropane dioxygenase
MC81_RS22615	COG1127	ABC transporter
MC81_RS22620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MC81_RS22625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MC81_RS22630	COG2853	Lipoprotein
MC81_RS22640	COG1131	(ABC) transporter
MC81_RS22645	COG0842	Transport permease protein
MC81_RS22655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MC81_RS22665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MC81_RS22670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MC81_RS22675	COG0131	Imidazoleglycerol-phosphate dehydratase
MC81_RS22680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MC81_RS22685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MC81_RS22690	COG0107	imidazoleglycerol-phosphate synthase activity
MC81_RS22700	COG0140	phosphoribosyl-ATP diphosphatase activity
MC81_RS22705	COG0537	adenosine 5'-monophosphoramidase activity
MC81_RS22710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MC81_RS22715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MC81_RS22730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MC81_RS22735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MC81_RS22745	COG0477	Major facilitator Superfamily
MC81_RS22755	COG0235	Class ii aldolase
MC81_RS22760	COG1970	mechanosensitive ion channel activity
MC81_RS22765	COG0723	plastoquinol--plastocyanin reductase activity
MC81_RS22770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MC81_RS22775	COG2857	Cytochrome c1
MC81_RS22780	COG0625	glutathione transferase activity
MC81_RS22785	COG2969	positive regulation of protein catabolic process
MC81_RS22800	COG0154	amidase activity
MC81_RS22805	COG1414	Transcriptional regulator
MC81_RS22815	COG0583	DNA-binding transcription factor activity
MC81_RS22825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MC81_RS22835	COG3708	Transcriptional regulator
MC81_RS22835	COG2207	Transcriptional regulator
MC81_RS22845	COG1160	GTP binding
MC81_RS22850	COG0747	negative chemotaxis
MC81_RS22855	COG0601	transmembrane transport
MC81_RS22860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS22865	COG4172	Belongs to the ABC transporter superfamily
MC81_RS22875	COG5339	Protein conserved in bacteria
MC81_RS22880	COG0513	Belongs to the DEAD box helicase family
MC81_RS22885	COG1280	lysine exporter protein (LysE YggA)
MC81_RS22890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MC81_RS22910	COG0583	DNA-binding transcription factor activity
MC81_RS22920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MC81_RS22930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_RS22935	COG0154	amidase activity
MC81_RS22940	COG1609	Transcriptional regulator
MC81_RS22945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MC81_RS22950	COG3842	ATPase activity
MC81_RS22955	COG1653	transport
MC81_RS22960	COG1175	transmembrane transport
MC81_RS22965	COG0395	ABC-type sugar transport system, permease component
MC81_RS22980	COG0018	arginyl-trna synthetase
MC81_RS22990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MC81_RS23010	COG0778	Nitroreductase
MC81_RS23015	COG1280	lysine exporter protein (LysE YggA)
MC81_RS23030	COG1742	UPF0060 membrane protein
MC81_RS23040	COG1473	amidohydrolase
MC81_RS23045	COG1960	acyl-CoA dehydrogenase activity
MC81_RS23050	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MC81_RS23055	COG0183	Belongs to the thiolase family
MC81_RS23060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MC81_RS23095	COG0583	DNA-binding transcription factor activity
MC81_RS23115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS23145	COG2814	Major facilitator Superfamily
MC81_RS23180	COG3339	Conserved Protein
MC81_RS23195	COG1595	DNA-templated transcription, initiation
MC81_RS23200	COG3712	iron ion homeostasis
MC81_RS23245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MC81_RS23285	COG2358	TRAP transporter, solute receptor (TAXI family
MC81_RS23295	COG2922	Belongs to the Smg family
MC81_RS23300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MC81_RS23310	COG0551	DNA topoisomerase type I activity
MC81_RS23310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MC81_RS23320	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_RS23325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS23330	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS23335	COG0028	Belongs to the TPP enzyme family
MC81_RS23340	COG1522	sequence-specific DNA binding
MC81_RS23345	COG3781	membrane
MC81_RS23360	COG2814	Major facilitator Superfamily
MC81_RS23375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_RS23390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MC81_RS23395	COG0586	Pfam SNARE associated Golgi protein
MC81_RS23400	COG1744	ABC transporter substrate-binding protein PnrA-like
MC81_RS23405	COG3845	ABC transporter
MC81_RS23410	COG4603	Belongs to the binding-protein-dependent transport system permease family
MC81_RS23420	COG0402	S-adenosylhomocysteine deaminase activity
MC81_RS23435	COG1304	FMN binding
MC81_RS23460	COG1126	abc transporter atp-binding protein
MC81_RS23465	COG0765	amino acid transport
MC81_RS23470	COG0765	amino acid transport
MC81_RS23480	COG0583	DNA-binding transcription factor activity
MC81_RS23485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_RS23510	COG1917	Cupin 2, conserved barrel domain protein
MC81_RS23515	COG0154	amidase activity
MC81_RS23535	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MC81_RS23560	COG0583	DNA-binding transcription factor activity
MC81_RS23575	COG0592	DNA-directed DNA polymerase activity
MC81_RS23580	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MC81_RS23585	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MC81_RS23590	COG0594	ribonuclease P activity
MC81_RS23595	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MC81_RS23605	COG0753	catalase activity
MC81_RS23615	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_RS23625	COG2175	clavaminate synthase activity
MC81_RS23630	COG1473	amidohydrolase
MC81_RS23635	COG4608	Belongs to the ABC transporter superfamily
MC81_RS23640	COG0444	Belongs to the ABC transporter superfamily
MC81_RS23645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS23650	COG0601	transmembrane transport
MC81_RS23660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MC81_RS23685	COG0038	chloride channel
MC81_RS23695	COG0642	Histidine kinase
MC81_RS23715	COG0436	Aminotransferase
MC81_RS23720	COG3180	Ammonia monooxygenase
MC81_RS23725	COG1278	Cold shock
MC81_RS23730	COG0445	tRNA wobble uridine modification
MC81_RS23735	COG0357	Ribosomal RNA small subunit methyltransferase G
MC81_RS23740	COG1192	Involved in chromosome partitioning
MC81_RS23750	COG1475	DNA binding
MC81_RS23755	COG0252	asparaginase activity
MC81_RS23760	COG0583	DNA-binding transcription factor activity
MC81_RS23785	COG1349	DNA-binding transcription factor activity
MC81_RS23795	COG3842	ATPase activity
MC81_RS23800	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_RS23815	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS23840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MC81_RS23850	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MC81_RS23860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MC81_RS23865	COG0081	regulation of translation
MC81_RS23870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MC81_RS23875	COG0222	ribosome binding
MC81_RS23880	COG0085	RNA polymerase activity
MC81_RS23885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MC81_RS23900	COG5002	protein histidine kinase activity
MC81_RS23915	COG0745	RESPONSE REGULATOR receiver
MC81_RS23920	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MC81_RS23925	COG0049	tRNA binding
MC81_RS23930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MC81_RS23935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MC81_RS23940	COG0051	transcription antitermination factor activity, RNA binding
MC81_RS23945	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MC81_RS23955	COG0089	rRNA binding
MC81_RS23960	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MC81_RS23965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MC81_RS23970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MC81_RS23975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MC81_RS23980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MC81_RS23985	COG0255	Belongs to the universal ribosomal protein uL29 family
MC81_RS23990	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MC81_RS24005	COG4177	L-phenylalanine transmembrane transporter activity
MC81_RS24010	COG1126	abc transporter atp-binding protein
MC81_RS24015	COG1137	ATPase activity
MC81_RS24030	COG2207	Transcriptional regulator
MC81_RS24045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MC81_RS24050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MC81_RS24055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MC81_RS24060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MC81_RS24065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MC81_RS24070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MC81_RS24075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MC81_RS24080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MC81_RS24085	COG1841	ribosomal large subunit assembly
MC81_RS24090	COG0200	Binds to the 23S rRNA
MC81_RS24095	COG0201	protein transport
MC81_RS24100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MC81_RS24105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MC81_RS24110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MC81_RS24115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MC81_RS24120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MC81_RS24125	COG0202	RNA polymerase activity
MC81_RS24130	COG0203	ribosomal protein L17
MC81_RS24135	COG0537	adenosine 5'-monophosphoramidase activity
MC81_RS24140	COG1324	tolerance protein
MC81_RS24145	COG4232	protein-disulfide reductase activity
MC81_RS24155	COG1053	succinate dehydrogenase
MC81_RS24160	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS24165	COG0683	leucine binding
MC81_RS24195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MC81_RS24205	COG1333	cytochrome c biogenesis protein
MC81_RS24210	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MC81_RS24330	COG0019	diaminopimelate decarboxylase activity
MC81_RS24340	COG1965	Belongs to the frataxin family
MC81_RS24350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MC81_RS24355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MC81_RS24360	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MC81_RS24365	COG1473	amidohydrolase
MC81_RS24375	COG0583	DNA-binding transcription factor activity
MC81_RS24390	COG2814	Major facilitator Superfamily
MC81_RS24430	COG2186	Transcriptional regulator
MC81_RS24455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS24460	COG1956	GAF domain-containing protein
MC81_RS24465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_RS24480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MC81_RS24495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MC81_RS24525	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MC81_RS24530	COG3568	Endonuclease Exonuclease Phosphatase
MC81_RS24565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MC81_RS24570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MC81_RS24575	COG0697	spore germination
MC81_RS24580	COG2814	Major facilitator Superfamily
MC81_RS24630	COG1215	transferase activity, transferring glycosyl groups
MC81_RS24635	COG0482	sulfurtransferase activity
MC81_RS24640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MC81_RS24650	COG1086	Polysaccharide biosynthesis protein
MC81_RS24675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MC81_RS24690	COG0859	PFAM glycosyl transferase family 9
MC81_RS24705	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MC81_RS24715	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MC81_RS24750	COG1686	Belongs to the peptidase S11 family
MC81_RS24765	COG0321	lipoyl(octanoyl) transferase activity
MC81_RS24780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MC81_RS24795	COG2096	Adenosyltransferase
MC81_RS24805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MC81_RS24810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MC81_RS24820	COG0523	cobalamin synthesis protein
MC81_RS24825	COG0735	belongs to the Fur family
MC81_RS24850	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
MC81_RS24855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MC81_RS24865	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MC81_RS24880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MC81_RS24885	COG0154	amidase activity
MC81_RS24890	COG0477	Major facilitator Superfamily
MC81_RS24925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_RS24930	COG0583	DNA-binding transcription factor activity
MC81_RS24935	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS24945	COG0066	3-isopropylmalate dehydratase activity
MC81_RS24950	COG0596	Alpha beta hydrolase
MC81_RS24965	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MC81_RS24970	COG1950	PFAM Membrane protein of
MC81_RS24975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MC81_RS24980	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS24985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS25015	COG1305	Transglutaminase-like
MC81_RS25025	COG2308	Evidence 4 Homologs of previously reported genes of
MC81_RS25030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MC81_RS25040	COG0617	tRNA 3'-terminal CCA addition
MC81_RS25050	COG0513	Belongs to the DEAD box helicase family
MC81_RS25055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MC81_RS25060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MC81_RS25060	COG0352	thiamine-phosphate diphosphorylase activity
MC81_RS25060	COG0351	phosphomethylpyrimidine kinase
MC81_RS25070	COG3189	MarR family transcriptional regulator
MC81_RS25110	COG0640	Transcriptional regulator
MC81_RS25130	COG0730	response to heat
MC81_RS25175	COG1846	Transcriptional regulator
MC81_RS25180	COG1764	response to oxidative stress
MC81_RS25205	COG0583	DNA-binding transcription factor activity
MC81_RS25220	COG0583	DNA-binding transcription factor activity
MC81_RS25230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MC81_RS25245	COG0708	Exodeoxyribonuclease III
MC81_RS25250	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MC81_RS25260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MC81_RS25265	COG0154	amidase activity
MC81_RS25270	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MC81_RS25275	COG1077	Cell shape determining protein MreB Mrl
MC81_RS25280	COG1792	Involved in formation and maintenance of cell shape
MC81_RS25290	COG0768	penicillin binding
MC81_RS25295	COG0772	Belongs to the SEDS family
MC81_RS25300	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MC81_RS25305	COG0471	metal ion transport
MC81_RS25310	COG1309	transcriptional regulator
MC81_RS25320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MC81_RS25330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_RS25335	COG2823	Periplasmic or secreted lipoprotein
MC81_RS25340	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MC81_RS25355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MC81_RS25365	COG1660	Displays ATPase and GTPase activities
MC81_RS25380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS25385	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MC81_RS25395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MC81_RS25400	COG1137	ATPase activity
MC81_RS25415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MC81_RS25425	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MC81_RS25435	COG1271	oxidase subunit
MC81_RS25440	COG1294	oxidase, subunit
MC81_RS25450	COG4988	ABC transporter
MC81_RS25455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MC81_RS25460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MC81_RS25475	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_RS25480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC81_RS25485	COG1238	metal cluster binding
MC81_RS25500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MC81_RS25505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS25510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS25525	COG0758	DNA mediated transformation
MC81_RS25530	COG0242	peptide deformylase activity
MC81_RS25535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MC81_RS25545	COG0546	phosphoglycolate phosphatase activity
MC81_RS25565	COG1733	regulation of RNA biosynthetic process
MC81_RS25575	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MC81_RS25585	COG1280	lysine exporter protein (LysE YggA)
MC81_RS25590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MC81_RS25600	COG5000	phosphorelay sensor kinase activity
MC81_RS25605	COG2204	response regulator
MC81_RS25610	COG0569	domain protein
MC81_RS25615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MC81_RS25620	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MC81_RS25625	COG2226	methyltransferase
MC81_RS25630	COG1040	competence protein
MC81_RS25635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MC81_RS25645	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MC81_RS25650	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MC81_RS25655	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MC81_RS25660	COG1054	Belongs to the UPF0176 family
MC81_RS25665	COG0588	phosphoglycerate mutase activity
MC81_RS25670	COG4942	peptidase
MC81_RS25675	COG0793	Belongs to the peptidase S41A family
MC81_RS25680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MC81_RS25690	COG2186	Transcriptional regulator
MC81_RS25705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MC81_RS25720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MC81_RS25725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MC81_RS25730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MC81_RS25735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MC81_RS25750	COG0142	geranyltranstransferase activity
MC81_RS25760	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MC81_RS25770	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS25775	COG3119	arylsulfatase activity
MC81_RS25785	COG4585	Histidine kinase
MC81_RS25800	COG4774	siderophore transport
MC81_RS25810	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS25820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MC81_RS25825	COG1802	Transcriptional regulator
MC81_RS25830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MC81_RS25835	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MC81_RS25840	COG1335	isochorismatase
MC81_RS25845	COG0523	cobalamin synthesis protein
MC81_RS25855	COG2226	methyltransferase
MC81_RS25855	COG1073	alpha beta
MC81_RS25885	COG0683	leucine binding
MC81_RS25890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MC81_RS25895	COG2084	Dehydrogenase
MC81_RS25910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MC81_RS25925	COG0235	Class ii aldolase
MC81_RS25930	COG2271	Major facilitator Superfamily
MC81_RS25935	COG3622	Belongs to the hyi family
MC81_RS25940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC81_RS25945	COG2084	Dehydrogenase
MC81_RS25950	COG3395	kinase activity
MC81_RS25955	COG2186	Transcriptional regulator
MC81_RS25980	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS25985	COG0022	dehydrogenase e1 component
MC81_RS26000	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_RS26010	COG0583	DNA-binding transcription factor activity
MC81_RS26015	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS26045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS26050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_RS26055	COG3622	Belongs to the hyi family
MC81_RS26080	COG1522	sequence-specific DNA binding
MC81_RS26110	COG1132	(ABC) transporter
MC81_RS26120	COG1196	nuclear chromosome segregation
MC81_RS26120	COG3264	Mechanosensitive ion channel
MC81_RS26135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MC81_RS26140	COG2890	protein-(glutamine-N5) methyltransferase activity
MC81_RS26145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MC81_RS26160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_RS26170	COG4829	muconolactone delta-isomerase
MC81_RS26175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_RS26185	COG1414	Transcriptional regulator
MC81_RS26190	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS26195	COG2031	fatty acid transporter
MC81_RS26200	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS26205	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MC81_RS26210	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MC81_RS26225	COG0583	DNA-binding transcription factor activity
MC81_RS26230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_RS26240	COG0129	dihydroxy-acid dehydratase activity
MC81_RS26250	COG0477	Major facilitator Superfamily
MC81_RS26260	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MC81_RS26265	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MC81_RS26285	COG0237	dephospho-CoA kinase activity
MC81_RS26290	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MC81_RS26320	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS26325	COG0583	DNA-binding transcription factor activity
MC81_RS26330	COG0154	amidase activity
MC81_RS26335	COG0683	leucine binding
MC81_RS26380	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MC81_RS26440	COG2202	Pas domain
MC81_RS26440	COG2200	EAL domain
MC81_RS26440	COG2199	diguanylate cyclase activity
MC81_RS26450	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS26455	COG1024	Enoyl-CoA hydratase
MC81_RS26495	COG4638	Rieske (2fe-2S)
MC81_RS26500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MC81_RS26505	COG1335	isochorismatase
MC81_RS26510	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS26520	COG0741	lytic transglycosylase activity
MC81_RS26525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MC81_RS26530	COG0352	thiamine-phosphate diphosphorylase activity
MC81_RS26535	COG0352	thiamine-phosphate diphosphorylase activity
MC81_RS26535	COG0351	phosphomethylpyrimidine kinase
MC81_RS26535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MC81_RS26545	COG1678	Uncharacterized ACR, COG1678
MC81_RS26550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MC81_RS26555	COG0540	Belongs to the ATCase OTCase family
MC81_RS26575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_RS26580	COG0436	Aminotransferase
MC81_RS26585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_RS26595	COG0765	amino acid transport
MC81_RS26600	COG1126	abc transporter atp-binding protein
MC81_RS26605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MC81_RS26615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MC81_RS26620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MC81_RS26635	COG1175	transmembrane transport
MC81_RS26655	COG0557	exoribonuclease II activity
MC81_RS26660	COG3150	esterase
MC81_RS26665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MC81_RS26670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_RS26675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MC81_RS26680	COG0511	ligase activity, forming carbon-carbon bonds
MC81_RS26685	COG0439	Biotin carboxylase
MC81_RS26690	COG2264	protein methyltransferase activity
MC81_RS26700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MC81_RS26700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MC81_RS26725	COG1696	Membrane protein involved in D-alanine export
MC81_RS26730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MC81_RS26735	COG0762	integral membrane protein
MC81_RS26760	COG1522	sequence-specific DNA binding
MC81_RS26765	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS26775	COG0583	DNA-binding transcription factor activity
MC81_RS26790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MC81_RS26795	COG1042	CoA-binding domain protein
MC81_RS26795	COG0045	succinate-CoA ligase (ADP-forming) activity
MC81_RS26795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MC81_RS26800	COG1335	isochorismatase
MC81_RS26805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS26810	COG1116	anion transmembrane transporter activity
MC81_RS26830	COG0312	modulator of DNA gyrase
MC81_RS26835	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MC81_RS26845	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_RS26850	COG4177	L-phenylalanine transmembrane transporter activity
MC81_RS26865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MC81_RS26870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MC81_RS26875	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MC81_RS26885	COG0316	Belongs to the HesB IscA family
MC81_RS26890	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MC81_RS26900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MC81_RS26905	COG1881	PFAM PEBP family protein
MC81_RS26915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MC81_RS26920	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MC81_RS26935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MC81_RS26935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MC81_RS26950	COG2766	serine protein kinase
MC81_RS26955	COG2718	Belongs to the UPF0229 family
MC81_RS26960	COG2719	SpoVR family
MC81_RS26980	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS27005	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS27030	COG3608	succinylglutamate desuccinylase aspartoacylase
MC81_RS27035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC81_RS27040	COG0741	lytic transglycosylase activity
MC81_RS27040	COG1388	LysM domain
MC81_RS27045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MC81_RS27050	COG2226	methyltransferase
MC81_RS27055	COG0328	RNA-DNA hybrid ribonuclease activity
MC81_RS27060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_RS27065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_RS27085	COG1671	Belongs to the UPF0178 family
MC81_RS27100	COG0786	glutamate:sodium symporter activity
MC81_RS27110	COG0463	Glycosyl transferase, family 2
MC81_RS27130	COG0583	DNA-binding transcription factor activity
MC81_RS27145	COG0583	DNA-binding transcription factor activity
MC81_RS27155	COG1346	cytolysis
MC81_RS27165	COG0697	spore germination
MC81_RS27170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS27185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MC81_RS27195	COG1522	sequence-specific DNA binding
MC81_RS27210	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MC81_RS27215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC81_RS27230	COG0823	Involved in the tonB-independent uptake of proteins
MC81_RS27240	COG0848	biopolymer transport protein
MC81_RS27245	COG0811	peptide transport
MC81_RS27250	COG0824	Thioesterase
MC81_RS27285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_RS27300	COG2084	Dehydrogenase
MC81_RS27345	COG0129	dihydroxy-acid dehydratase activity
MC81_RS27350	COG4654	Cytochrome c, class I
MC81_RS27355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_RS27365	COG1522	sequence-specific DNA binding
MC81_RS27425	COG1473	amidohydrolase
MC81_RS27430	COG0418	dihydroorotase activity
MC81_RS27435	COG0488	(ABC) transporter
MC81_RS27445	COG2001	Belongs to the MraZ family
MC81_RS27450	COG0275	rRNA processing
MC81_RS27455	COG3116	cell division
MC81_RS27465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MC81_RS27470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MC81_RS27475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MC81_RS27485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MC81_RS27490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MC81_RS27495	COG1181	Belongs to the D-alanine--D-alanine ligase family
MC81_RS27500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MC81_RS27510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MC81_RS27515	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MC81_RS27525	COG0739	heme binding
MC81_RS27530	COG0653	protein targeting
MC81_RS27545	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS27550	COG0028	Belongs to the TPP enzyme family
MC81_RS27560	COG0300	oxidoreductase activity
MC81_RS27565	COG1522	sequence-specific DNA binding
MC81_RS27580	COG2239	Acts as a magnesium transporter
MC81_RS27590	COG2855	membrane
MC81_RS27600	COG1473	amidohydrolase
MC81_RS27605	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS27615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_RS27615	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MC81_RS27620	COG1501	Belongs to the glycosyl hydrolase 31 family
MC81_RS27625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MC81_RS27630	COG2011	ABC-type metal ion transport system permease component
MC81_RS27655	COG0735	belongs to the Fur family
MC81_RS27675	COG2818	Glycosylase
MC81_RS27680	COG1368	sulfuric ester hydrolase activity
MC81_RS27685	COG2982	Protein involved in outer membrane biogenesis
MC81_RS27700	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS27715	COG1522	sequence-specific DNA binding
MC81_RS27725	COG0436	Aminotransferase
MC81_RS27745	COG2154	pterin-4-alpha-carbinolamine dehydratase
MC81_RS27770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MC81_RS27785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_RS27790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MC81_RS27795	COG1929	Belongs to the glycerate kinase type-1 family
MC81_RS27800	COG0469	pyruvate kinase activity
MC81_RS27805	COG0700	Nucleoside recognition
MC81_RS27815	COG0242	peptide deformylase activity
MC81_RS27835	COG0204	Acyl-transferase
MC81_RS27840	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MC81_RS27845	COG0751	glycine-tRNA ligase activity
MC81_RS27850	COG0752	glycyl-tRNA synthetase alpha subunit
MC81_RS27855	COG1024	Enoyl-CoA hydratase
MC81_RS27865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS27870	COG2030	dehydratase
MC81_RS27875	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS27880	COG0583	DNA-binding transcription factor activity
MC81_RS27900	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS27915	COG1960	acyl-CoA dehydrogenase activity
MC81_RS27925	COG1024	Enoyl-CoA hydratase
MC81_RS27930	COG0583	DNA-binding transcription factor activity
MC81_RS27935	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MC81_RS27940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS27950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MC81_RS27960	COG0617	tRNA 3'-terminal CCA addition
MC81_RS27975	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MC81_RS27980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MC81_RS27985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MC81_RS27990	COG0586	Pfam SNARE associated Golgi protein
MC81_RS27995	COG0860	N-Acetylmuramoyl-L-alanine amidase
MC81_RS28000	COG0802	atpase or kinase
MC81_RS28005	COG0114	fumarate hydratase activity
MC81_RS28015	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS28025	COG0405	Gamma-glutamyltransferase
MC81_RS28030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS28035	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS28040	COG1960	acyl-CoA dehydrogenase activity
MC81_RS28045	COG0583	DNA-binding transcription factor activity
MC81_RS28050	COG0659	secondary active sulfate transmembrane transporter activity
MC81_RS28060	COG0579	oxidoreductase
MC81_RS28070	COG0259	pyridoxamine-phosphate oxidase activity
MC81_RS28085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_RS28090	COG1136	(ABC) transporter
MC81_RS28090	COG0577	efflux transmembrane transporter activity
MC81_RS28095	COG1538	Outer membrane efflux protein
MC81_RS28100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MC81_RS28135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MC81_RS28160	COG1216	Glycosyl transferase, family 2
MC81_RS28160	COG0463	Glycosyl transferase, family 2
MC81_RS28185	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS28190	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MC81_RS28215	COG4638	Rieske (2fe-2S)
MC81_RS28240	COG4166	transmembrane transport
MC81_RS28245	COG0601	transmembrane transport
MC81_RS28250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS28255	COG0444	Belongs to the ABC transporter superfamily
MC81_RS28260	COG4608	Belongs to the ABC transporter superfamily
MC81_RS28280	COG0488	(ABC) transporter
MC81_RS28295	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MC81_RS28300	COG2894	cell division
MC81_RS28305	COG0850	regulation of cytokinetic process
MC81_RS28310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MC81_RS28315	COG1271	oxidase subunit
MC81_RS28325	COG0514	ATP-dependent DNA helicase (RecQ)
MC81_RS28345	COG2255	four-way junction helicase activity
MC81_RS28355	COG1090	epimerase
MC81_RS28360	COG0632	four-way junction helicase activity
MC81_RS28365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MC81_RS28385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_RS28395	COG0006	proline dipeptidase activity
MC81_RS28410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MC81_RS28415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_RS28430	COG4783	chaperone-mediated protein folding
MC81_RS28435	COG0429	hydrolase of the alpha beta-hydrolase fold
MC81_RS28465	COG0513	Belongs to the DEAD box helicase family
MC81_RS28480	COG1058	Belongs to the CinA family
MC81_RS28480	COG1546	Belongs to the CinA family
MC81_RS28485	COG1414	Transcriptional regulator
MC81_RS28500	COG0167	dihydroorotate dehydrogenase activity
MC81_RS28505	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MC81_RS28510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MC81_RS28520	COG0583	DNA-binding transcription factor activity
MC81_RS28565	COG1475	DNA binding
MC81_RS28570	COG3969	phosphoadenosine phosphosulfate
MC81_RS28575	COG0784	Response regulator, receiver
MC81_RS28575	COG2205	protein histidine kinase activity
MC81_RS28580	COG2199	diguanylate cyclase activity
MC81_RS28580	COG2202	Pas domain
MC81_RS28580	COG2200	EAL domain
MC81_RS28590	COG2197	response regulator
MC81_RS28600	COG3121	Chaperone
MC81_RS28605	COG3188	usher protein
MC81_RS28615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MC81_RS28630	COG1053	succinate dehydrogenase
MC81_RS28670	COG0583	DNA-binding transcription factor activity
MC81_RS28705	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC81_RS28710	COG0735	belongs to the Fur family
MC81_RS28715	COG0497	DNA recombination
MC81_RS28725	COG1420	regulation of RNA biosynthetic process
MC81_RS28730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MC81_RS28740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MC81_RS28750	COG0443	Heat shock 70 kDa protein
MC81_RS28755	COG0484	heat shock protein binding
MC81_RS28765	COG0612	Peptidase, M16
MC81_RS28790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MC81_RS28825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_RS28840	COG0745	RESPONSE REGULATOR receiver
MC81_RS28845	COG2205	protein histidine kinase activity
MC81_RS28850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MC81_RS28855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MC81_RS28860	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MC81_RS28875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MC81_RS28885	COG1193	negative regulation of DNA recombination
MC81_RS28890	COG0492	ferredoxin-NADP+ reductase activity
MC81_RS28895	COG1674	ftsk spoiiie
MC81_RS28900	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MC81_RS28910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MC81_RS28915	COG1737	Transcriptional regulator
MC81_RS28935	COG0601	transmembrane transport
MC81_RS28940	COG0747	negative chemotaxis
MC81_RS28950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC81_RS28955	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MC81_RS28960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MC81_RS29005	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MC81_RS29015	COG0477	Major facilitator Superfamily
MC81_RS29020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC81_RS29025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_RS29030	COG0840	transmembrane signaling receptor activity
MC81_RS29045	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS29050	COG3022	response to hydroperoxide
MC81_RS29055	COG1289	transmembrane transporter activity
MC81_RS29060	COG0028	Belongs to the TPP enzyme family
MC81_RS29065	COG0440	acetolactate synthase activity
MC81_RS29070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MC81_RS29075	COG1183	phosphatidylcholine synthase activity
MC81_RS29085	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MC81_RS29090	COG1185	polyribonucleotide nucleotidyltransferase activity
MC81_RS29100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC81_RS29130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS29140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_RS29155	COG1696	Membrane protein involved in D-alanine export
MC81_RS29165	COG3321	synthase
MC81_RS29165	COG0604	alcohol dehydrogenase
MC81_RS29170	COG0149	triose-phosphate isomerase activity
MC81_RS29175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MC81_RS29180	COG1737	Transcriptional regulator
MC81_RS29185	COG0647	UMP catabolic process
MC81_RS29195	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MC81_RS29210	COG0583	DNA-binding transcription factor activity
MC81_RS29215	COG5383	Protein conserved in bacteria
MC81_RS29240	COG0071	Belongs to the small heat shock protein (HSP20) family
MC81_RS29250	COG2072	flavoprotein involved in K transport
MC81_RS29255	COG3842	ATPase activity
MC81_RS29260	COG0604	alcohol dehydrogenase
MC81_RS29260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MC81_RS29260	COG4221	oxidoreductase activity
MC81_RS29260	COG3321	synthase
MC81_RS29270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MC81_RS29275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_RS29280	COG1177	transmembrane transport
MC81_RS29285	COG1176	ABC-type spermidine putrescine transport system, permease component I
MC81_RS29295	COG1126	abc transporter atp-binding protein
MC81_RS29335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_RS29345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MC81_RS29370	COG1024	Enoyl-CoA hydratase
MC81_RS29385	COG1960	acyl-CoA dehydrogenase activity
MC81_RS29400	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MC81_RS29405	COG4608	Belongs to the ABC transporter superfamily
MC81_RS29410	COG0444	Belongs to the ABC transporter superfamily
MC81_RS29415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_RS29420	COG0601	transmembrane transport
MC81_RS29425	COG0747	negative chemotaxis
MC81_RS29445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MC81_RS29490	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS29495	COG1971	Probably functions as a manganese efflux pump
MC81_RS29500	COG0583	DNA-binding transcription factor activity
MC81_RS29505	COG3048	D-serine ammonia-lyase activity
MC81_RS29525	COG0697	spore germination
MC81_RS29530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_RS29575	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS29605	COG0642	Histidine kinase
MC81_RS29615	COG2851	Citrate transporter
MC81_RS29620	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS29630	COG3119	arylsulfatase activity
MC81_RS29640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS29645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS29650	COG2084	Dehydrogenase
MC81_RS29655	COG1609	Transcriptional regulator
MC81_RS29665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MC81_RS29680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS29685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_RS29700	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_RS29700	COG0022	dehydrogenase e1 component
MC81_RS29710	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_RS29720	COG0477	Major facilitator Superfamily
MC81_RS29730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MC81_RS29735	COG0583	DNA-binding transcription factor activity
MC81_RS29740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS29745	COG0604	alcohol dehydrogenase
MC81_RS29755	COG3604	Transcriptional regulator
MC81_RS29760	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MC81_RS29765	COG3813	Protein conserved in bacteria
MC81_RS29770	COG2354	Protein conserved in bacteria
MC81_RS29800	COG0747	negative chemotaxis
MC81_RS29805	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS29815	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MC81_RS29840	COG0726	polysaccharide deacetylase
MC81_RS29860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_RS29870	COG1309	transcriptional regulator
MC81_RS29880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MC81_RS29890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_RS29910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_RS29915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_RS29920	COG1309	transcriptional regulator
MC81_RS29945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MC81_RS29970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_RS29975	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC81_RS29980	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC81_RS29985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC81_RS29995	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MC81_RS30005	COG1034	ATP synthesis coupled electron transport
MC81_RS30010	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MC81_RS30015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC81_RS30025	COG0713	ATP synthesis coupled electron transport
MC81_RS30040	COG1007	ATP synthesis coupled electron transport
MC81_RS30050	COG4774	siderophore transport
MC81_RS30055	COG0560	Phosphoserine phosphatase
MC81_RS30060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MC81_RS30065	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MC81_RS30070	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MC81_RS30080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MC81_RS30085	COG0450	alkyl hydroperoxide reductase
MC81_RS30100	COG1214	PFAM Peptidase M22, glycoprotease
MC81_RS30105	COG1573	uracil-dna glycosylase
MC81_RS30110	COG0477	Major facilitator Superfamily
MC81_RS30115	COG1196	nuclear chromosome segregation
MC81_RS30125	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MC81_RS30130	COG1414	Transcriptional regulator
MC81_RS30145	COG2175	clavaminate synthase activity
MC81_RS30150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_RS30155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_RS30165	COG2917	probably involved in intracellular septation
MC81_RS30170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_RS30175	COG1122	ATPase activity
MC81_RS30180	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MC81_RS30185	COG1268	BioY protein
MC81_RS30220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MC81_RS30255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MC81_RS30260	COG2878	Part of a membrane complex involved in electron transport
MC81_RS30275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MC81_RS30280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MC81_RS30285	COG0251	oxidation-reduction process
MC81_RS30290	COG0655	NAD(P)H dehydrogenase (quinone) activity
MC81_RS30295	COG3228	Belongs to the MtfA family
MC81_RS30300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MC81_RS30310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_RS30320	COG0159	tryptophan synthase activity
MC81_RS30325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MC81_RS30330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MC81_RS30340	COG2721	sulfolactate sulfo-lyase activity
MC81_RS30675	COG0789	Transcriptional regulator
MC81_RS30680	COG2608	mercury ion transmembrane transporter activity
MC81_RS30685	COG2608	mercury ion transmembrane transporter activity
MC81_RS30695	COG0789	Transcriptional regulator
MC81_RS30745	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MC81_RS30755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_RS30755	COG1017	nitric oxide dioxygenase activity
MC81_RS30760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MC81_RS30765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_RS30780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_RS30795	COG3253	May function as heme-dependent peroxidase
MC81_RS30810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MC81_RS30825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_RS30835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MC81_RS31090	COG1960	acyl-CoA dehydrogenase activity
MC81_RS31095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS31145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS31150	COG2204	response regulator
MC81_RS31160	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MC81_RS31165	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_RS31170	COG1024	Enoyl-CoA hydratase
MC81_RS31175	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS31185	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS31190	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS31200	COG0604	alcohol dehydrogenase
MC81_RS31210	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS31220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS31245	COG1024	Enoyl-CoA hydratase
MC81_RS31250	COG1024	Enoyl-CoA hydratase
MC81_RS31265	COG1012	belongs to the aldehyde dehydrogenase family
MC81_RS31265	COG2030	dehydratase
MC81_RS31275	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS31300	COG4221	oxidoreductase activity
MC81_RS31350	COG0667	Aldo Keto reductase
MC81_RS31375	COG4221	oxidoreductase activity
MC81_RS31380	COG3386	PFAM SMP-30 Gluconolaconase
MC81_RS31395	COG0028	Belongs to the TPP enzyme family
MC81_RS31400	COG3386	PFAM SMP-30 Gluconolaconase
MC81_RS31405	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS31410	COG1802	Transcriptional regulator
MC81_RS31420	COG2207	Transcriptional regulator
MC81_RS31475	COG2070	2-Nitropropane dioxygenase
MC81_RS31480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MC81_RS31490	COG0656	L-ascorbic acid biosynthetic process
MC81_RS31500	COG0667	Aldo Keto reductase
MC81_RS31565	COG2030	dehydratase
MC81_RS31570	COG1960	acyl-CoA dehydrogenase activity
MC81_RS31575	COG1053	succinate dehydrogenase
MC81_RS31600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS31615	COG1960	acyl-CoA dehydrogenase activity
MC81_RS31620	COG1960	acyl-CoA dehydrogenase activity
MC81_RS31625	COG0183	Belongs to the thiolase family
MC81_RS31645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MC81_RS31650	COG1960	acyl-CoA dehydrogenase activity
MC81_RS31655	COG1024	Enoyl-CoA hydratase
MC81_RS31670	COG0183	Belongs to the thiolase family
MC81_RS31675	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS31675	COG1024	Enoyl-CoA hydratase
MC81_RS31690	COG1846	Transcriptional regulator
MC81_RS31700	COG0446	pyridine nucleotide-disulphide oxidoreductase
MC81_RS31700	COG1902	pentaerythritol trinitrate reductase activity
MC81_RS31705	COG1024	Enoyl-CoA hydratase
MC81_RS31715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS31720	COG1960	acyl-CoA dehydrogenase activity
MC81_RS31730	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS31740	COG0604	alcohol dehydrogenase
MC81_RS31750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS31780	COG0583	DNA-binding transcription factor activity
MC81_RS31790	COG2084	Dehydrogenase
MC81_RS31820	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_RS31830	COG1902	pentaerythritol trinitrate reductase activity
MC81_RS31845	COG1024	Enoyl-CoA hydratase
MC81_RS31850	COG1024	Enoyl-CoA hydratase
MC81_RS31855	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_RS31865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS31875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MC81_RS31890	COG1024	Enoyl-CoA hydratase
MC81_RS31890	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_RS31895	COG0583	DNA-binding transcription factor activity
MC81_RS31905	COG1414	Transcriptional regulator
MC81_RS31925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_RS31970	COG1475	DNA binding
MC81_RS31975	COG1192	Involved in chromosome partitioning