CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 SMART SM00304 179 231 8.8E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 393 8.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 8.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 418 8.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 Gene3D G3DSA:3.30.565.10 295 447 1.3E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 SUPERFAMILY SSF47384 216 290 2.55E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 SMART SM00387 330 440 4.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 SMART SM00388 232 290 2.4E-4 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 438 1.0E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 SUPERFAMILY SSF55874 293 437 1.27E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS10325 b2f67133274b7075a368b67c330dbeaf 448 Gene3D G3DSA:1.10.287.130 222 294 3.0E-6 T 29-03-2018 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 387 5.5E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 Gene3D G3DSA:1.10.540.10 1 130 2.3E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 SUPERFAMILY SSF47203 238 390 9.67E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 SUPERFAMILY SSF56645 1 250 1.05E-59 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 Gene3D G3DSA:1.20.140.10 229 394 1.1E-45 T 29-03-2018 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 PIRSF PIRSF016578 24 88 5.1 T 29-03-2018 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 PIRSF PIRSF016578 249 393 1.0E-11 T 29-03-2018 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 PIRSF PIRSF016578 141 202 0.27 T 29-03-2018 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 125 3.6E-17 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 226 3.2E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS01205 9602df2977a73bc9e3508f0e5a969ab7 408 Gene3D G3DSA:2.40.110.10 131 228 1.6E-31 T 29-03-2018 CVS48_RS10370 fa878def4b111078cba647ce02533faf 232 Pfam PF02798 Glutathione S-transferase, N-terminal domain 21 98 5.2E-13 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS10370 fa878def4b111078cba647ce02533faf 232 Gene3D G3DSA:1.20.1050.10 157 226 6.3E-15 T 29-03-2018 CVS48_RS10370 fa878def4b111078cba647ce02533faf 232 Gene3D G3DSA:1.20.1050.10 112 156 1.3E-11 T 29-03-2018 CVS48_RS10370 fa878def4b111078cba647ce02533faf 232 SUPERFAMILY SSF52833 12 102 2.96E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS10370 fa878def4b111078cba647ce02533faf 232 Gene3D G3DSA:3.40.30.10 18 111 1.0E-24 T 29-03-2018 CVS48_RS10370 fa878def4b111078cba647ce02533faf 232 SUPERFAMILY SSF47616 102 229 1.67E-31 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS10370 fa878def4b111078cba647ce02533faf 232 Pfam PF00043 Glutathione S-transferase, C-terminal domain 142 222 6.0E-9 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS25260 8af3b6cbd14b69ff86eb38bb080e80a2 826 Pfam PF07715 TonB-dependent Receptor Plug Domain 152 250 9.6E-11 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS25260 8af3b6cbd14b69ff86eb38bb080e80a2 826 SUPERFAMILY SSF56935 114 826 1.1E-120 T 29-03-2018 CVS48_RS25260 8af3b6cbd14b69ff86eb38bb080e80a2 826 Pfam PF00593 TonB dependent receptor 333 823 4.0E-50 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS25260 8af3b6cbd14b69ff86eb38bb080e80a2 826 SMART SM00965 61 111 2.6E-7 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS25260 8af3b6cbd14b69ff86eb38bb080e80a2 826 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 154 826 6.8E-104 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS25260 8af3b6cbd14b69ff86eb38bb080e80a2 826 Gene3D G3DSA:2.170.130.10 114 257 2.2E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS25260 8af3b6cbd14b69ff86eb38bb080e80a2 826 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 809 826 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS25260 8af3b6cbd14b69ff86eb38bb080e80a2 826 Gene3D G3DSA:2.40.170.20 258 826 1.1E-81 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS01780 84a69a7b0ae25af73acb02626c5591d3 330 Gene3D G3DSA:3.40.190.10 158 300 2.8E-8 T 29-03-2018 CVS48_RS01780 84a69a7b0ae25af73acb02626c5591d3 330 PIRSF PIRSF017082 1 329 4.2E-83 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01780 84a69a7b0ae25af73acb02626c5591d3 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 326 7.5E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01780 84a69a7b0ae25af73acb02626c5591d3 330 SUPERFAMILY SSF53850 117 291 7.76E-6 T 29-03-2018 CVS48_RS16395 05b5511e9c10b35f1f0a2beb4991a9c3 114 Pfam PF01638 HxlR-like helix-turn-helix 20 107 4.2E-32 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CVS48_RS16395 05b5511e9c10b35f1f0a2beb4991a9c3 114 Gene3D G3DSA:1.10.10.10 17 113 1.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16395 05b5511e9c10b35f1f0a2beb4991a9c3 114 SUPERFAMILY SSF46785 6 107 1.65E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 Gene3D G3DSA:3.40.190.10 180 271 1.3E-19 T 29-03-2018 CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 SUPERFAMILY SSF53850 90 298 2.28E-45 T 29-03-2018 CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 Gene3D G3DSA:1.10.10.10 1 87 5.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 4.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 4.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 4.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 Pfam PF03466 LysR substrate binding domain 92 297 8.6E-44 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 Gene3D G3DSA:3.40.190.10 92 179 7.3E-22 T 29-03-2018 CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.7E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15785 984c7189517a3f7bb59791fe3ee899bb 302 SUPERFAMILY SSF46785 7 89 6.15E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10990 bdfc8fae8dc8f758a5afccf8da726aea 552 SMART SM00880 242 544 6.9E-54 T 29-03-2018 IPR007899 CHAD domain CVS48_RS10990 bdfc8fae8dc8f758a5afccf8da726aea 552 Gene3D G3DSA:2.40.320.10 1 206 1.2E-28 T 29-03-2018 CVS48_RS10990 bdfc8fae8dc8f758a5afccf8da726aea 552 SMART SM01118 1 193 3.4E-25 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CVS48_RS10990 bdfc8fae8dc8f758a5afccf8da726aea 552 SUPERFAMILY SSF55154 1 191 1.41E-30 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CVS48_RS10990 bdfc8fae8dc8f758a5afccf8da726aea 552 Pfam PF01928 CYTH domain 1 185 5.0E-19 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CVS48_RS10990 bdfc8fae8dc8f758a5afccf8da726aea 552 Pfam PF05235 CHAD domain 243 508 5.3E-43 T 29-03-2018 IPR007899 CHAD domain CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 SUPERFAMILY SSF48008 96 234 1.83E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 Gene3D G3DSA:1.20.120.530 85 246 1.8E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 SMART SM00345 16 75 1.2E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 SUPERFAMILY SSF46785 9 79 3.18E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 SMART SM00895 99 228 6.8E-22 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 Pfam PF07729 FCD domain 99 227 3.6E-23 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 2.1E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS06870 30da6ad175808da58cb43956d5150696 254 Gene3D G3DSA:1.10.10.10 2 77 6.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12705 003ad5f56834e5ab81e6e9d54d1579d8 371 Pfam PF04303 PrpF protein 4 356 3.6E-123 T 29-03-2018 IPR007400 PrpF protein CVS48_RS12705 003ad5f56834e5ab81e6e9d54d1579d8 371 SUPERFAMILY SSF54506 3 166 1.88E-64 T 29-03-2018 CVS48_RS12705 003ad5f56834e5ab81e6e9d54d1579d8 371 SUPERFAMILY SSF54506 171 358 1.33E-54 T 29-03-2018 CVS48_RS12705 003ad5f56834e5ab81e6e9d54d1579d8 371 Gene3D G3DSA:3.10.310.10 176 339 3.2E-51 T 29-03-2018 CVS48_RS12705 003ad5f56834e5ab81e6e9d54d1579d8 371 Gene3D G3DSA:3.10.310.10 1 175 5.2E-73 T 29-03-2018 CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 Pfam PF03466 LysR substrate binding domain 95 298 8.2E-40 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 SUPERFAMILY SSF46785 3 115 2.53E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 Gene3D G3DSA:1.10.10.10 2 90 4.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 Gene3D G3DSA:3.40.190.10 183 281 2.2E-16 T 29-03-2018 CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 66 4.1E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 SUPERFAMILY SSF53850 95 301 3.53E-36 T 29-03-2018 CVS48_RS24255 dde3f2ca2b492c74c326ac324faead7a 313 Gene3D G3DSA:3.40.190.10 93 182 4.0E-22 T 29-03-2018 CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 Gene3D G3DSA:1.10.10.10 3 84 4.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 SUPERFAMILY SSF46785 4 86 4.54E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.8E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 Gene3D G3DSA:3.40.190.10 176 264 2.7E-27 T 29-03-2018 CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.5E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 Pfam PF03466 LysR substrate binding domain 88 293 1.7E-43 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 SUPERFAMILY SSF53850 89 296 2.53E-47 T 29-03-2018 CVS48_RS07375 e74b752d7104f220aed3c476e52ef98b 307 Gene3D G3DSA:3.40.190.10 88 175 1.7E-13 T 29-03-2018 CVS48_RS01370 45f4dc815a712c4860ceb9833b296683 368 Gene3D G3DSA:2.40.160.10 30 368 5.6E-50 T 29-03-2018 CVS48_RS01370 45f4dc815a712c4860ceb9833b296683 368 SUPERFAMILY SSF56935 30 368 4.27E-54 T 29-03-2018 CVS48_RS01370 45f4dc815a712c4860ceb9833b296683 368 Pfam PF13609 Gram-negative porin 18 341 5.6E-41 T 29-03-2018 CVS48_RS28815 d2deb6cfa06415e5e9241495b51f23f9 531 Gene3D G3DSA:3.10.105.10 308 501 2.6E-40 T 29-03-2018 CVS48_RS28815 d2deb6cfa06415e5e9241495b51f23f9 531 Gene3D G3DSA:3.40.190.10 167 307 1.6E-23 T 29-03-2018 CVS48_RS28815 d2deb6cfa06415e5e9241495b51f23f9 531 PIRSF PIRSF002741 4 521 4.8E-90 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS28815 d2deb6cfa06415e5e9241495b51f23f9 531 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 85 107 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CVS48_RS28815 d2deb6cfa06415e5e9241495b51f23f9 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 444 1.5E-74 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS28815 d2deb6cfa06415e5e9241495b51f23f9 531 SUPERFAMILY SSF53850 30 514 3.58E-108 T 29-03-2018 CVS48_RS28815 d2deb6cfa06415e5e9241495b51f23f9 531 Gene3D G3DSA:3.90.76.10 53 166 4.0E-28 T 29-03-2018 CVS48_RS17335 8e829ff59dfc3e80c107d94609b2d6ae 315 Pfam PF00491 Arginase family 42 313 5.1E-57 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS17335 8e829ff59dfc3e80c107d94609b2d6ae 315 PIRSF PIRSF036979 18 315 4.0E-28 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS17335 8e829ff59dfc3e80c107d94609b2d6ae 315 Gene3D G3DSA:3.40.800.10 1 315 4.5E-76 T 29-03-2018 CVS48_RS17335 8e829ff59dfc3e80c107d94609b2d6ae 315 ProSitePatterns PS01053 Arginase family signature. 243 264 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CVS48_RS17335 8e829ff59dfc3e80c107d94609b2d6ae 315 Hamap MF_00737 Formimidoylglutamase [hutG]. 6 314 40.631 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CVS48_RS17335 8e829ff59dfc3e80c107d94609b2d6ae 315 PRINTS PR00116 Arginase signature 121 136 4.2E-5 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS17335 8e829ff59dfc3e80c107d94609b2d6ae 315 PRINTS PR00116 Arginase signature 240 269 4.2E-5 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS17335 8e829ff59dfc3e80c107d94609b2d6ae 315 TIGRFAM TIGR01227 hutG: formimidoylglutamase 11 313 4.6E-85 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CVS48_RS17335 8e829ff59dfc3e80c107d94609b2d6ae 315 SUPERFAMILY SSF52768 16 313 9.36E-75 T 29-03-2018 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 ProSitePatterns PS00447 DNA polymerase family A signature. 731 750 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 731 756 5.4E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 633 655 5.4E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 677 700 5.4E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 707 720 5.4E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 768 779 5.4E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 822 838 5.4E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 790 801 5.4E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 852 865 5.4E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 SUPERFAMILY SSF88723 1 166 3.92E-56 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Gene3D G3DSA:3.30.420.10 301 520 3.0E-45 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Gene3D G3DSA:1.10.150.20 181 257 2.1E-20 T 29-03-2018 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 SMART SM00279 169 204 7.5E-12 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 166 7.1E-54 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 167 254 5.4E-22 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Pfam PF01612 3'-5' exonuclease 310 495 4.6E-38 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Pfam PF00476 DNA polymerase family A 529 902 5.5E-151 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 SUPERFAMILY SSF53098 309 495 1.61E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 SMART SM00482 664 869 9.8E-105 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Gene3D G3DSA:3.30.70.370 635 723 1.7E-15 T 29-03-2018 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Gene3D G3DSA:3.30.70.370 731 905 1.6E-49 T 29-03-2018 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Gene3D G3DSA:3.40.50.1010 3 180 1.4E-67 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 SMART SM00475 2 260 1.1E-109 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 SUPERFAMILY SSF47807 167 283 6.28E-30 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 SMART SM00474 310 496 8.7E-31 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 TIGRFAM TIGR00593 pola: DNA polymerase I 5 905 2.6E-269 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 Gene3D G3DSA:1.20.1060.10 521 634 1.7E-35 T 29-03-2018 CVS48_RS27120 e6e66e3eee693561acc12c4baf532f42 905 SUPERFAMILY SSF56672 501 905 3.45E-149 T 29-03-2018 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Gene3D G3DSA:3.30.420.110 122 254 1.2E-23 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Gene3D G3DSA:3.40.50.300 570 837 1.8E-38 T 29-03-2018 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Pfam PF05188 MutS domain II 121 245 7.0E-18 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 863 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 SUPERFAMILY SSF52540 570 799 1.23E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Gene3D G3DSA:1.10.1420.10 411 538 5.7E-29 T 29-03-2018 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Gene3D G3DSA:3.40.1170.10 1 121 1.1E-38 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 SMART SM00533 275 594 6.2E-89 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Gene3D G3DSA:1.10.1420.10 255 410 5.9E-34 T 29-03-2018 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Pfam PF05190 MutS family domain IV 431 522 3.9E-29 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 SUPERFAMILY SSF53150 108 272 9.42E-37 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 SUPERFAMILY SSF55271 1 106 6.41E-37 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 PIRSF PIRSF037677 1 178 6.4E-20 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 PIRSF PIRSF037677 204 844 7.7E-113 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 SUPERFAMILY SSF48334 259 568 6.8E-84 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 690 706 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 1 857 24.107 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 SMART SM00534 609 796 8.0E-105 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Pfam PF01624 MutS domain I 1 110 6.3E-38 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Pfam PF05192 MutS domain III 262 561 2.8E-34 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CVS48_RS24655 52ea810b9a22e0f023cd02aee13505c4 866 Pfam PF00488 MutS domain V 613 799 7.8E-80 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CVS48_RS12495 3b237a5acd24b2497947f2e7f59617d1 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 215 1.8E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS12495 3b237a5acd24b2497947f2e7f59617d1 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 1.2E-29 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS12495 3b237a5acd24b2497947f2e7f59617d1 226 SUPERFAMILY SSF161098 13 201 3.79E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS12495 3b237a5acd24b2497947f2e7f59617d1 226 Gene3D G3DSA:1.10.3720.10 8 218 8.1E-35 T 29-03-2018 CVS48_RS24645 c989b26144b00afabd319929eea04e00 82 Gene3D G3DSA:1.10.10.10 13 64 6.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24645 c989b26144b00afabd319929eea04e00 82 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 10 56 8.7E-12 T 29-03-2018 IPR010260 DNA-binding transcriptional activator AlpA CVS48_RS09040 1383faf5b21df86d03fd1b2d3a4572c9 250 Gene3D G3DSA:1.10.3720.10 4 247 2.0E-25 T 29-03-2018 CVS48_RS09040 1383faf5b21df86d03fd1b2d3a4572c9 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 242 2.2E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09040 1383faf5b21df86d03fd1b2d3a4572c9 250 SUPERFAMILY SSF161098 49 230 1.07E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS11640 e158c23b8c11cd12392a18fe36566f1a 481 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 471 6.3E-51 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS11640 e158c23b8c11cd12392a18fe36566f1a 481 Gene3D G3DSA:3.30.465.10 97 240 2.7E-32 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS11640 e158c23b8c11cd12392a18fe36566f1a 481 Pfam PF01565 FAD binding domain 44 181 3.9E-31 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS11640 e158c23b8c11cd12392a18fe36566f1a 481 Gene3D G3DSA:3.30.43.10 2 96 1.7E-26 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS11640 e158c23b8c11cd12392a18fe36566f1a 481 SUPERFAMILY SSF56176 6 221 1.52E-68 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS11640 e158c23b8c11cd12392a18fe36566f1a 481 Gene3D G3DSA:1.10.45.10 433 472 2.7E-10 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CVS48_RS11640 e158c23b8c11cd12392a18fe36566f1a 481 SUPERFAMILY SSF55103 224 476 1.36E-55 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS25895 2917fb63b60116d1d31ae432a2a01f43 344 SUPERFAMILY SSF46689 281 331 3.0E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS25895 2917fb63b60116d1d31ae432a2a01f43 344 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 312 328 4.1E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS25895 2917fb63b60116d1d31ae432a2a01f43 344 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 312 4.1E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS25895 2917fb63b60116d1d31ae432a2a01f43 344 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 202 9.7E-33 T 29-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CVS48_RS25895 2917fb63b60116d1d31ae432a2a01f43 344 Gene3D G3DSA:1.10.10.10 10 98 0.3 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25895 2917fb63b60116d1d31ae432a2a01f43 344 SMART SM00342 245 328 6.5E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS25895 2917fb63b60116d1d31ae432a2a01f43 344 Gene3D G3DSA:1.10.10.60 224 279 0.0011 T 29-03-2018 CVS48_RS25895 2917fb63b60116d1d31ae432a2a01f43 344 Gene3D G3DSA:1.10.10.60 280 331 2.0E-15 T 29-03-2018 CVS48_RS25895 2917fb63b60116d1d31ae432a2a01f43 344 Pfam PF12833 Helix-turn-helix domain 253 330 1.1E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 SUPERFAMILY SSF48264 35 441 1.03E-86 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 Gene3D G3DSA:3.40.50.80 567 677 4.6E-17 T 29-03-2018 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 732 740 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 Gene3D G3DSA:3.10.20.30 678 784 4.0E-20 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 SUPERFAMILY SSF63380 470 565 9.46E-25 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 Pfam PF00067 Cytochrome P450 261 409 1.3E-19 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 382 391 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 PRINTS PR00359 B-class P450 signature 358 373 2.0E-33 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 PRINTS PR00359 B-class P450 signature 380 389 2.0E-33 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 PRINTS PR00359 B-class P450 signature 124 135 2.0E-33 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 PRINTS PR00359 B-class P450 signature 170 186 2.0E-33 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 PRINTS PR00359 B-class P450 signature 313 324 2.0E-33 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 PRINTS PR00359 B-class P450 signature 330 357 2.0E-33 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 PRINTS PR00359 B-class P450 signature 187 202 2.0E-33 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 PRINTS PR00359 B-class P450 signature 389 400 2.0E-33 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 701 773 2.4E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 Gene3D G3DSA:1.10.630.10 30 448 4.7E-66 T 29-03-2018 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 Gene3D G3DSA:2.40.30.10 463 566 2.9E-17 T 29-03-2018 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 SUPERFAMILY SSF54292 673 783 1.7E-26 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 SUPERFAMILY SSF52343 566 681 1.15E-23 T 29-03-2018 CVS48_RS10305 5d8126655b04769a2615e2ff5679133d 784 Pfam PF00175 Oxidoreductase NAD-binding domain 578 664 3.2E-4 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS07435 c448875dc1b3923d538640bf0c0ff30b 267 Gene3D G3DSA:3.90.260.10 134 249 1.9E-5 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS07435 c448875dc1b3923d538640bf0c0ff30b 267 SMART SM00460 158 220 5.6E-16 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS07435 c448875dc1b3923d538640bf0c0ff30b 267 SUPERFAMILY SSF54001 7 246 2.26E-38 T 29-03-2018 CVS48_RS07435 c448875dc1b3923d538640bf0c0ff30b 267 Pfam PF01841 Transglutaminase-like superfamily 129 217 7.0E-24 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS07435 c448875dc1b3923d538640bf0c0ff30b 267 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 5 79 2.3E-20 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CVS48_RS25165 7d0a9ac0abb20a3fad3a138f043f21ff 426 PIRSF PIRSF006066 1 426 2.3E-137 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS25165 7d0a9ac0abb20a3fad3a138f043f21ff 426 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 419 2.1E-144 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS25165 7d0a9ac0abb20a3fad3a138f043f21ff 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 416 6.3E-117 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS23610 bfdc699a95a4af0fda5672194468b20a 318 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 11 314 5.7E-47 T 29-03-2018 IPR017592 Pilus assembly, Flp-type CpaB CVS48_RS23610 bfdc699a95a4af0fda5672194468b20a 318 Gene3D G3DSA:3.90.1210.10 50 129 1.7E-12 T 29-03-2018 CVS48_RS23610 bfdc699a95a4af0fda5672194468b20a 318 Pfam PF08666 SAF domain 56 114 1.3E-8 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS23610 bfdc699a95a4af0fda5672194468b20a 318 SMART SM00858 54 115 1.2E-8 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS23610 bfdc699a95a4af0fda5672194468b20a 318 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 117 229 3.0E-28 T 29-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 SUPERFAMILY SSF158472 317 365 1.96E-6 T 29-03-2018 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 Pfam PF00512 His Kinase A (phospho-acceptor) domain 514 581 1.6E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 Pfam PF08448 PAS fold 388 505 2.5E-6 T 29-03-2018 IPR013656 PAS fold-4 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 634 747 1.2E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 PIRSF PIRSF037532 1 755 2.6E-238 T 29-03-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 Pfam PF00672 HAMP domain 316 364 1.3E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 SMART SM00388 513 585 1.3E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 Gene3D G3DSA:1.10.287.130 506 581 3.7E-10 T 29-03-2018 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 SUPERFAMILY SSF55874 574 749 8.77E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 697 2.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 PRINTS PR00344 Bacterial sensor protein C-terminal signature 701 711 2.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 PRINTS PR00344 Bacterial sensor protein C-terminal signature 712 730 2.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 SUPERFAMILY SSF47384 502 582 4.71E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 SMART SM00304 316 368 7.3E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 SMART SM00387 634 752 1.9E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 SUPERFAMILY SSF55785 374 503 5.93E-11 T 29-03-2018 IPR000014 PAS domain CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 Gene3D G3DSA:3.30.450.20 361 505 2.5E-16 T 29-03-2018 CVS48_RS07945 86f29dd284fe2c8d143c694de8cc0df2 771 Gene3D G3DSA:3.30.565.10 585 763 6.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 SUPERFAMILY SSF52210 301 453 6.15E-22 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 Pfam PF13549 ATP-grasp domain 476 696 4.0E-48 T 29-03-2018 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 Gene3D G3DSA:3.30.1490.20 490 556 0.024 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 Gene3D G3DSA:3.30.470.20 557 698 6.8E-31 T 29-03-2018 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 SUPERFAMILY SSF52210 144 294 8.5E-40 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 SUPERFAMILY SSF51735 3 136 2.78E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 Pfam PF13380 CoA binding domain 11 134 1.2E-21 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 156 292 7.3E-50 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 Gene3D G3DSA:3.40.50.720 3 125 2.0E-37 T 29-03-2018 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 Gene3D G3DSA:3.40.50.261 299 461 1.1E-27 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 Gene3D G3DSA:3.40.50.261 126 298 2.1E-39 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 SMART SM00881 7 102 1.9E-33 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS25105 5de8df18d41a939f94da3f35e1ebdaf8 698 SUPERFAMILY SSF56059 480 697 3.03E-33 T 29-03-2018 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 897 0.0 T 29-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 SUPERFAMILY SSF63737 9 197 1.22E-40 T 29-03-2018 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 Gene3D G3DSA:1.25.50.10 573 898 1.1E-120 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 Gene3D G3DSA:2.60.40.1730 17 197 1.0E-27 T 29-03-2018 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 464 572 3.9E-24 T 29-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 Pfam PF01433 Peptidase family M1 domain 212 443 2.2E-55 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 298 313 1.3E-7 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 262 272 1.3E-7 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 317 329 1.3E-7 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 180 195 1.3E-7 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 SUPERFAMILY SSF55486 208 470 2.05E-71 T 29-03-2018 CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 575 898 5.0E-114 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal CVS48_RS26680 1e1d3795de6dafb1285f4d3ba4b21e69 901 Gene3D G3DSA:1.10.390.10 284 463 4.3E-48 T 29-03-2018 CVS48_RS15040 737e19cbe75b52721c01c3adb265caf1 338 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 36 292 2.2E-84 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS15040 737e19cbe75b52721c01c3adb265caf1 338 PIRSF PIRSF006470 4 335 4.2E-119 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS15040 737e19cbe75b52721c01c3adb265caf1 338 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 318 1.3E-94 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS29125 5ad42c437424f566dd88b89025aad3d5 163 Gene3D G3DSA:3.30.70.260 1 87 5.2E-26 T 29-03-2018 CVS48_RS29125 5ad42c437424f566dd88b89025aad3d5 163 SUPERFAMILY SSF55021 1 76 5.39E-23 T 29-03-2018 CVS48_RS29125 5ad42c437424f566dd88b89025aad3d5 163 SUPERFAMILY SSF55021 79 162 2.44E-25 T 29-03-2018 CVS48_RS29125 5ad42c437424f566dd88b89025aad3d5 163 Pfam PF13710 ACT domain 12 73 7.6E-16 T 29-03-2018 CVS48_RS29125 5ad42c437424f566dd88b89025aad3d5 163 Gene3D G3DSA:3.30.70.1150 88 159 1.8E-26 T 29-03-2018 CVS48_RS29125 5ad42c437424f566dd88b89025aad3d5 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 9.1E-27 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CVS48_RS29125 5ad42c437424f566dd88b89025aad3d5 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 2.9E-64 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CVS48_RS29125 5ad42c437424f566dd88b89025aad3d5 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-34 T 29-03-2018 CVS48_RS00070 5ad42c437424f566dd88b89025aad3d5 163 Gene3D G3DSA:3.30.70.260 1 87 5.2E-26 T 29-03-2018 CVS48_RS00070 5ad42c437424f566dd88b89025aad3d5 163 SUPERFAMILY SSF55021 1 76 5.39E-23 T 29-03-2018 CVS48_RS00070 5ad42c437424f566dd88b89025aad3d5 163 SUPERFAMILY SSF55021 79 162 2.44E-25 T 29-03-2018 CVS48_RS00070 5ad42c437424f566dd88b89025aad3d5 163 Pfam PF13710 ACT domain 12 73 7.6E-16 T 29-03-2018 CVS48_RS00070 5ad42c437424f566dd88b89025aad3d5 163 Gene3D G3DSA:3.30.70.1150 88 159 1.8E-26 T 29-03-2018 CVS48_RS00070 5ad42c437424f566dd88b89025aad3d5 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 9.1E-27 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CVS48_RS00070 5ad42c437424f566dd88b89025aad3d5 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 2.9E-64 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CVS48_RS00070 5ad42c437424f566dd88b89025aad3d5 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-34 T 29-03-2018 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 414 744 2.5E-65 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 Gene3D G3DSA:3.50.50.60 1 394 3.6E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 Gene3D G3DSA:3.20.20.70 399 781 3.9E-116 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.2E-8 T 29-03-2018 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 131 146 1.2E-8 T 29-03-2018 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.2E-8 T 29-03-2018 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.2E-8 T 29-03-2018 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 SUPERFAMILY SSF51395 412 764 4.79E-117 T 29-03-2018 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 SUPERFAMILY SSF51905 1 152 1.26E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS03430 97217605abf2688307c413232cf0ef20 783 SUPERFAMILY SSF51905 254 358 1.26E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS07695 041f340917ea6ca8e01f25baa00b1129 200 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 6 195 35.651 T 29-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 CVS48_RS07695 041f340917ea6ca8e01f25baa00b1129 200 Pfam PF13580 SIS domain 14 149 6.8E-33 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CVS48_RS07695 041f340917ea6ca8e01f25baa00b1129 200 SUPERFAMILY SSF53697 5 194 9.51E-55 T 29-03-2018 CVS48_RS07695 041f340917ea6ca8e01f25baa00b1129 200 Gene3D G3DSA:3.40.50.10490 5 198 1.1E-37 T 29-03-2018 CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 Pfam PF00082 Subtilase family 228 444 4.2E-11 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 SMART SM00495 573 621 1.6 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 SMART SM00495 819 870 5.0E-9 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 Gene3D G3DSA:2.10.10.20 561 625 9.3E-8 T 29-03-2018 CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 SUPERFAMILY SSF52743 178 469 1.18E-29 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 Gene3D G3DSA:3.40.1850.10 733 822 1.4E-10 T 29-03-2018 CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 SUPERFAMILY SSF51055 572 622 2.35E-5 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 SUPERFAMILY SSF49299 633 717 4.71E-5 T 29-03-2018 IPR000601 PKD domain CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 SUPERFAMILY SSF49299 693 812 1.12E-5 T 29-03-2018 IPR000601 PKD domain CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 Gene3D G3DSA:3.40.50.200 176 482 2.0E-26 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 405 415 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 Gene3D G3DSA:2.60.40.10 483 560 3.1E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 Gene3D G3DSA:2.60.40.10 629 718 1.3E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 SMART SM00089 727 813 0.044 T 29-03-2018 IPR022409 PKD/Chitinase domain CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 SMART SM00089 635 719 0.74 T 29-03-2018 IPR022409 PKD/Chitinase domain CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 SMART SM00089 481 565 14.0 T 29-03-2018 IPR022409 PKD/Chitinase domain CVS48_RS01000 795e3944b1a400d2db71c0c055c94865 874 Gene3D G3DSA:2.10.10.20 823 872 1.0E-10 T 29-03-2018 CVS48_RS15045 9559c6cec46efd9c00c77b81268b3a89 426 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 420 2.7E-142 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS15045 9559c6cec46efd9c00c77b81268b3a89 426 PIRSF PIRSF006066 1 426 4.0E-144 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS15045 9559c6cec46efd9c00c77b81268b3a89 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 417 6.4E-116 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS03075 3aefe0a028ce52380fba6a75dbe0d3bb 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 276 7.3E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03075 3aefe0a028ce52380fba6a75dbe0d3bb 278 Gene3D G3DSA:1.10.3720.10 36 278 2.8E-25 T 29-03-2018 CVS48_RS03075 3aefe0a028ce52380fba6a75dbe0d3bb 278 SUPERFAMILY SSF161098 81 261 1.09E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27830 392dc7ec3918e4e091129ed62b7fac8d 120 Pfam PF00576 HIUase/Transthyretin family 3 119 4.0E-34 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CVS48_RS27830 392dc7ec3918e4e091129ed62b7fac8d 120 Gene3D G3DSA:2.60.40.180 1 120 5.2E-36 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CVS48_RS27830 392dc7ec3918e4e091129ed62b7fac8d 120 SUPERFAMILY SSF49472 3 120 2.22E-37 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CVS48_RS27830 392dc7ec3918e4e091129ed62b7fac8d 120 ProSitePatterns PS00768 Transthyretin signature 1. 6 21 - T 29-03-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CVS48_RS27830 392dc7ec3918e4e091129ed62b7fac8d 120 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 3 120 2.1E-35 T 29-03-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CVS48_RS27830 392dc7ec3918e4e091129ed62b7fac8d 120 PRINTS PR00189 Transthyretin signature 98 120 2.0E-7 T 29-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CVS48_RS27830 392dc7ec3918e4e091129ed62b7fac8d 120 PRINTS PR00189 Transthyretin signature 2 22 2.0E-7 T 29-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CVS48_RS27830 392dc7ec3918e4e091129ed62b7fac8d 120 ProSitePatterns PS00769 Transthyretin signature 2. 103 115 - T 29-03-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 SUPERFAMILY SSF54909 77 152 4.83E-9 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 Pfam PF13404 AsnC-type helix-turn-helix domain 16 56 5.3E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 Pfam PF01037 Lrp/AsnC ligand binding domain 82 151 3.9E-6 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 SUPERFAMILY SSF54909 240 319 1.26E-8 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 200 218 - T 29-03-2018 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 Gene3D G3DSA:1.10.10.10 179 236 2.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 SUPERFAMILY SSF46785 180 235 2.78E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 SUPERFAMILY SSF46785 16 63 6.83E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 16 32 3.6E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 43 3.6E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 62 3.6E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 Gene3D G3DSA:3.30.70.920 69 162 5.6E-12 T 29-03-2018 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 Gene3D G3DSA:3.30.70.920 237 325 6.3E-12 T 29-03-2018 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 Gene3D G3DSA:1.10.10.10 14 65 2.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 SMART SM00344 16 121 3.4E-13 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 SMART SM00344 181 286 1.9E-4 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS07330 fd7092e792a8769e20b5028e182fbce8 335 Pfam PF09339 IclR helix-turn-helix domain 189 227 4.3E-7 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS19620 68850d9297fe5a7e3af98b99f1b222ef 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 293 3.8E-42 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS19620 68850d9297fe5a7e3af98b99f1b222ef 324 SUPERFAMILY SSF53850 106 280 1.12E-5 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1042 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 Pfam PF00873 AcrB/AcrD/AcrF family 1 1027 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 SUPERFAMILY SSF82693 135 182 4.71E-26 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 SUPERFAMILY SSF82693 274 330 4.71E-26 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 SUPERFAMILY SSF82714 724 810 9.94E-22 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 Gene3D G3DSA:3.30.70.1440 674 770 1.1E-22 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 SUPERFAMILY SSF82693 38 131 2.96E-27 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 SUPERFAMILY SSF82714 182 271 3.53E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 SUPERFAMILY SSF82693 566 671 1.99E-25 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 Gene3D G3DSA:3.30.2090.10 180 275 1.5E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 SUPERFAMILY SSF82866 809 1030 1.96E-45 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 Gene3D G3DSA:1.20.1640.10 813 1031 9.2E-39 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 Gene3D G3DSA:3.30.70.1430 38 140 6.3E-29 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 Gene3D G3DSA:3.30.70.1430 568 670 4.9E-16 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 Gene3D G3DSA:1.20.1640.10 286 510 1.6E-45 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 SUPERFAMILY SSF82866 296 497 4.84E-50 T 29-03-2018 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.8E-110 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.8E-110 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.8E-110 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 1.8E-110 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.8E-110 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.8E-110 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.8E-110 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.8E-110 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS16635 d267ef51f38a6380df5694d066757bbf 1059 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.8E-110 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 Gene3D G3DSA:1.10.1040.10 292 506 3.0E-60 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 225 450 9.6E-66 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 30 196 1.3E-37 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 Gene3D G3DSA:3.40.50.720 3 290 4.1E-109 T 29-03-2018 CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 PRINTS PR00084 Mannitol dehydrogenase signature 187 200 4.7E-17 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 PRINTS PR00084 Mannitol dehydrogenase signature 31 41 4.7E-17 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 PRINTS PR00084 Mannitol dehydrogenase signature 256 271 4.7E-17 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 PRINTS PR00084 Mannitol dehydrogenase signature 226 239 4.7E-17 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 SUPERFAMILY SSF51735 6 285 3.23E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11105 022c3b1b775b1a65d30b4630afe6741a 506 SUPERFAMILY SSF48179 294 503 5.1E-52 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS27750 9fe05e6ecd756a610c262b13fe1dfa53 374 SUPERFAMILY SSF51905 311 368 4.79E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27750 9fe05e6ecd756a610c262b13fe1dfa53 374 SUPERFAMILY SSF51905 7 214 4.79E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27750 9fe05e6ecd756a610c262b13fe1dfa53 374 SUPERFAMILY SSF54373 210 310 3.53E-11 T 29-03-2018 CVS48_RS27750 9fe05e6ecd756a610c262b13fe1dfa53 374 Gene3D G3DSA:3.50.50.60 2 373 5.3E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27750 9fe05e6ecd756a610c262b13fe1dfa53 374 Pfam PF01266 FAD dependent oxidoreductase 7 349 2.6E-55 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 Gene3D G3DSA:3.40.50.720 163 315 3.0E-20 T 29-03-2018 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 Gene3D G3DSA:1.10.1200.70 334 418 2.8E-26 T 29-03-2018 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 6 411 7.0E-129 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 417 29.22 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 SUPERFAMILY SSF69742 5 160 9.02E-44 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 174 306 3.8E-43 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 322 417 3.3E-28 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 9 158 4.2E-45 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 SUPERFAMILY SSF69075 319 418 2.35E-28 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 PIRSF PIRSF000445 3 424 2.3E-146 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 101 124 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CVS48_RS09075 3abb685283aea5e07fd8fc32863604e1 424 SUPERFAMILY SSF51735 165 316 1.4E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS17440 4e5fd8e7ced09a12b982c9ebd187d3b8 330 SUPERFAMILY SSF53850 117 291 1.93E-11 T 29-03-2018 CVS48_RS17440 4e5fd8e7ced09a12b982c9ebd187d3b8 330 PIRSF PIRSF017082 1 330 9.5E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17440 4e5fd8e7ced09a12b982c9ebd187d3b8 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 326 1.8E-83 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17440 4e5fd8e7ced09a12b982c9ebd187d3b8 330 Gene3D G3DSA:3.40.190.10 130 240 3.6E-13 T 29-03-2018 CVS48_RS10880 15723f42dc87ff5072599efa8f43a4d0 199 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CVS48_RS10880 15723f42dc87ff5072599efa8f43a4d0 199 SUPERFAMILY SSF53178 5 193 1.7E-65 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CVS48_RS10880 15723f42dc87ff5072599efa8f43a4d0 199 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 5 186 34.976 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CVS48_RS10880 15723f42dc87ff5072599efa8f43a4d0 199 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 18 31 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CVS48_RS10880 15723f42dc87ff5072599efa8f43a4d0 199 Pfam PF01195 Peptidyl-tRNA hydrolase 7 184 1.3E-55 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CVS48_RS10880 15723f42dc87ff5072599efa8f43a4d0 199 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 180 1.5E-57 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CVS48_RS10880 15723f42dc87ff5072599efa8f43a4d0 199 Gene3D G3DSA:3.40.50.1470 3 198 2.3E-67 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 Gene3D G3DSA:1.10.10.10 1 78 2.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 60 1.5E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 Gene3D G3DSA:3.40.190.10 178 259 1.9E-15 T 29-03-2018 CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 Pfam PF03466 LysR substrate binding domain 86 283 2.2E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 Gene3D G3DSA:3.40.190.10 79 177 9.7E-16 T 29-03-2018 CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 SUPERFAMILY SSF46785 1 108 4.47E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04690 12c0b9ad97e02b02dfd148cae98ab715 301 SUPERFAMILY SSF53850 87 289 2.04E-34 T 29-03-2018 CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 SUPERFAMILY SSF54826 6 130 5.01E-32 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 195 226 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 129 1.3E-32 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 Gene3D G3DSA:3.20.20.120 134 374 7.8E-62 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 SUPERFAMILY SSF51604 117 373 4.06E-67 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 Pfam PF13378 Enolase C-terminal domain-like 152 365 2.1E-50 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 104 129 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 Gene3D G3DSA:3.30.390.10 1 133 9.4E-33 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 TIGRFAM TIGR02534 mucon_cyclo: muconate and chloromuconate cycloisomerases 7 373 5.6E-174 T 29-03-2018 IPR013370 Muconate/chloromuconate cycloisomerase GO:0018849|GO:0018850|GO:0030145 CVS48_RS17775 97af10814736f2e6dc99c0746ba2331c 374 SMART SM00922 147 245 7.9E-20 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CVS48_RS06875 35ca755ab994df611c2e8ba5a4fa74be 373 Gene3D G3DSA:3.40.50.720 7 139 4.1E-16 T 29-03-2018 CVS48_RS06875 35ca755ab994df611c2e8ba5a4fa74be 373 SUPERFAMILY SSF55347 125 361 4.77E-61 T 29-03-2018 CVS48_RS06875 35ca755ab994df611c2e8ba5a4fa74be 373 Gene3D G3DSA:3.30.360.10 140 303 3.0E-25 T 29-03-2018 CVS48_RS06875 35ca755ab994df611c2e8ba5a4fa74be 373 SUPERFAMILY SSF51735 9 179 1.36E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS06875 35ca755ab994df611c2e8ba5a4fa74be 373 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 9 99 2.6E-14 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CVS48_RS06875 35ca755ab994df611c2e8ba5a4fa74be 373 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 124 347 6.7E-15 T 29-03-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 CVS48_RS14405 ed2086d477cbecc20a28ccd5b2954bc0 499 SUPERFAMILY SSF53720 22 497 5.11E-174 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS14405 ed2086d477cbecc20a28ccd5b2954bc0 499 Gene3D G3DSA:3.40.605.10 9 287 2.7E-104 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS14405 ed2086d477cbecc20a28ccd5b2954bc0 499 Pfam PF00171 Aldehyde dehydrogenase family 32 495 1.6E-179 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS14405 ed2086d477cbecc20a28ccd5b2954bc0 499 Gene3D G3DSA:3.40.309.10 288 481 7.7E-76 T 29-03-2018 CVS48_RS14405 ed2086d477cbecc20a28ccd5b2954bc0 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 299 310 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS14405 ed2086d477cbecc20a28ccd5b2954bc0 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 271 278 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS01290 98a94ded6cd7829f9a6e98e0774b22d6 347 PIRSF PIRSF000164 16 347 8.5E-96 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CVS48_RS01290 98a94ded6cd7829f9a6e98e0774b22d6 347 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 8 345 1.2E-123 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CVS48_RS01290 98a94ded6cd7829f9a6e98e0774b22d6 347 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 7 344 49.015 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CVS48_RS01290 98a94ded6cd7829f9a6e98e0774b22d6 347 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CVS48_RS01290 98a94ded6cd7829f9a6e98e0774b22d6 347 Pfam PF01180 Dihydroorotate dehydrogenase 53 339 8.4E-88 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CVS48_RS01290 98a94ded6cd7829f9a6e98e0774b22d6 347 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CVS48_RS01290 98a94ded6cd7829f9a6e98e0774b22d6 347 SUPERFAMILY SSF51395 8 342 5.33E-102 T 29-03-2018 CVS48_RS01290 98a94ded6cd7829f9a6e98e0774b22d6 347 Gene3D G3DSA:3.20.20.70 2 346 5.8E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS06825 1a1f58559be6cfbec54bebbf550f165e 735 Pfam PF00593 TonB dependent receptor 247 734 6.6E-67 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS06825 1a1f58559be6cfbec54bebbf550f165e 735 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 74 734 4.9E-135 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS06825 1a1f58559be6cfbec54bebbf550f165e 735 Gene3D G3DSA:2.170.130.10 29 186 3.1E-28 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS06825 1a1f58559be6cfbec54bebbf550f165e 735 Pfam PF07715 TonB-dependent Receptor Plug Domain 73 173 3.3E-19 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS06825 1a1f58559be6cfbec54bebbf550f165e 735 SUPERFAMILY SSF56935 30 735 2.41E-145 T 29-03-2018 CVS48_RS06825 1a1f58559be6cfbec54bebbf550f165e 735 Gene3D G3DSA:2.40.170.20 187 735 1.1E-91 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS00035 eea4da9bad245e261ed32474d3dd75b0 405 Gene3D G3DSA:3.30.70.260 327 401 1.6E-7 T 29-03-2018 CVS48_RS00035 eea4da9bad245e261ed32474d3dd75b0 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 305 4.6E-74 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS00035 eea4da9bad245e261ed32474d3dd75b0 405 SUPERFAMILY SSF53686 5 354 6.29E-91 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS00035 eea4da9bad245e261ed32474d3dd75b0 405 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 399 2.0E-130 T 29-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CVS48_RS00035 eea4da9bad245e261ed32474d3dd75b0 405 Pfam PF01842 ACT domain 329 390 6.5E-7 T 29-03-2018 IPR002912 ACT domain CVS48_RS00035 eea4da9bad245e261ed32474d3dd75b0 405 Gene3D G3DSA:3.40.50.1100 113 322 9.5E-48 T 29-03-2018 CVS48_RS00035 eea4da9bad245e261ed32474d3dd75b0 405 Gene3D G3DSA:3.40.50.1100 1 112 5.6E-22 T 29-03-2018 CVS48_RS29090 eea4da9bad245e261ed32474d3dd75b0 405 Gene3D G3DSA:3.30.70.260 327 401 1.6E-7 T 29-03-2018 CVS48_RS29090 eea4da9bad245e261ed32474d3dd75b0 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 305 4.6E-74 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS29090 eea4da9bad245e261ed32474d3dd75b0 405 SUPERFAMILY SSF53686 5 354 6.29E-91 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS29090 eea4da9bad245e261ed32474d3dd75b0 405 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 399 2.0E-130 T 29-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CVS48_RS29090 eea4da9bad245e261ed32474d3dd75b0 405 Pfam PF01842 ACT domain 329 390 6.5E-7 T 29-03-2018 IPR002912 ACT domain CVS48_RS29090 eea4da9bad245e261ed32474d3dd75b0 405 Gene3D G3DSA:3.40.50.1100 113 322 9.5E-48 T 29-03-2018 CVS48_RS29090 eea4da9bad245e261ed32474d3dd75b0 405 Gene3D G3DSA:3.40.50.1100 1 112 5.6E-22 T 29-03-2018 CVS48_RS16730 40fb36d40a2fea467c039ed859ffbfaf 414 Gene3D G3DSA:3.40.50.150 253 351 0.22 T 29-03-2018 CVS48_RS16730 40fb36d40a2fea467c039ed859ffbfaf 414 Pfam PF08484 C-methyltransferase C-terminal domain 245 404 3.0E-60 T 29-03-2018 IPR013691 C-methyltransferase CVS48_RS16730 40fb36d40a2fea467c039ed859ffbfaf 414 SUPERFAMILY SSF53335 67 252 3.69E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS16730 40fb36d40a2fea467c039ed859ffbfaf 414 Gene3D G3DSA:3.40.50.150 55 252 1.1E-28 T 29-03-2018 CVS48_RS16730 40fb36d40a2fea467c039ed859ffbfaf 414 Pfam PF08421 Putative zinc binding domain 3 64 2.3E-21 T 29-03-2018 IPR013630 Methyltransferase putative zinc binding domain CVS48_RS16730 40fb36d40a2fea467c039ed859ffbfaf 414 Pfam PF13489 Methyltransferase domain 83 237 8.2E-15 T 29-03-2018 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 SMART SM00304 216 268 1.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 SUPERFAMILY SSF58104 236 519 1.01E-74 T 29-03-2018 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 Gene3D G3DSA:1.20.120.30 23 188 1.2E-19 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 Gene3D G3DSA:1.10.287.950 328 520 2.4E-49 T 29-03-2018 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 484 2.9E-56 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 Pfam PF00672 HAMP domain 216 264 9.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 61 76 1.0E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 367 394 1.0E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 191 211 1.0E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 425 1.0E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 1.0E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 444 473 1.0E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 319 1.0E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 Gene3D G3DSA:1.10.287.1060 235 327 0.33 T 29-03-2018 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 SMART SM00283 269 516 6.0E-92 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS21285 d0b17040d00dc38dc137c401648ef2f6 542 Pfam PF02203 Tar ligand binding domain homologue 1 169 5.3E-19 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 258 3.0E-64 T 29-03-2018 CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 6.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 6.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 Gene3D G3DSA:3.40.50.720 1 46 8.4E-4 T 29-03-2018 CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 Gene3D G3DSA:3.40.50.720 47 261 1.2E-65 T 29-03-2018 CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09110 6a2d1e6e52fde49429cae98713f4f285 262 SUPERFAMILY SSF51735 3 258 4.38E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS03270 6aff48efeefc5f1542a1e1b1b26f9260 241 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS03270 6aff48efeefc5f1542a1e1b1b26f9260 241 Pfam PF00005 ABC transporter 18 165 2.6E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS03270 6aff48efeefc5f1542a1e1b1b26f9260 241 Gene3D G3DSA:3.40.50.300 1 241 9.8E-77 T 29-03-2018 CVS48_RS03270 6aff48efeefc5f1542a1e1b1b26f9260 241 SUPERFAMILY SSF52540 1 234 6.46E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03270 6aff48efeefc5f1542a1e1b1b26f9260 241 PIRSF PIRSF039085 1 241 1.7E-107 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS03270 6aff48efeefc5f1542a1e1b1b26f9260 241 SMART SM00382 26 213 1.4E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS20005 46f3790e82e681f7f58e8c05298ba80a 576 Pfam PF01547 Bacterial extracellular solute-binding protein 84 424 9.2E-11 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CVS48_RS20005 46f3790e82e681f7f58e8c05298ba80a 576 Gene3D G3DSA:3.40.190.10 187 526 3.4E-32 T 29-03-2018 CVS48_RS20005 46f3790e82e681f7f58e8c05298ba80a 576 PIRSF PIRSF035859 1 575 0.0 T 29-03-2018 IPR014597 ABC transporter, periplasmic substrate-binding protein, predicted GO:0005215 CVS48_RS20005 46f3790e82e681f7f58e8c05298ba80a 576 SUPERFAMILY SSF53850 66 516 1.14E-62 T 29-03-2018 CVS48_RS14060 f6a3de71d49d8aa128cd31da041906a0 330 Pfam PF03466 LysR substrate binding domain 88 294 7.2E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS14060 f6a3de71d49d8aa128cd31da041906a0 330 Gene3D G3DSA:3.40.190.10 92 179 2.8E-11 T 29-03-2018 CVS48_RS14060 f6a3de71d49d8aa128cd31da041906a0 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.7E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS14060 f6a3de71d49d8aa128cd31da041906a0 330 SUPERFAMILY SSF46785 3 86 9.25E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14060 f6a3de71d49d8aa128cd31da041906a0 330 Gene3D G3DSA:3.40.190.10 180 265 1.4E-16 T 29-03-2018 CVS48_RS14060 f6a3de71d49d8aa128cd31da041906a0 330 Gene3D G3DSA:1.10.10.10 1 84 9.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14060 f6a3de71d49d8aa128cd31da041906a0 330 SUPERFAMILY SSF53850 89 298 1.66E-38 T 29-03-2018 CVS48_RS15795 20046d70eae23f349f7a694f6ec526cb 148 Pfam PF01850 PIN domain 9 119 1.5E-20 T 29-03-2018 IPR002716 PIN domain CVS48_RS15795 20046d70eae23f349f7a694f6ec526cb 148 SUPERFAMILY SSF88723 8 122 8.13E-24 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS15795 20046d70eae23f349f7a694f6ec526cb 148 Gene3D G3DSA:3.40.50.1010 7 145 6.2E-23 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS12695 2bcfa3aea1b759df7678236973730005 158 SUPERFAMILY SSF55729 9 141 5.89E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS12695 2bcfa3aea1b759df7678236973730005 158 Pfam PF00583 Acetyltransferase (GNAT) family 41 135 5.5E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS12695 2bcfa3aea1b759df7678236973730005 158 Gene3D G3DSA:3.40.630.30 8 153 4.7E-26 T 29-03-2018 CVS48_RS16825 ad7136cff0f57ce60bf25035a32e9e3a 504 SMART SM00283 56 324 2.4E-29 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS16825 ad7136cff0f57ce60bf25035a32e9e3a 504 SUPERFAMILY SSF58104 32 318 1.24E-45 T 29-03-2018 CVS48_RS16825 ad7136cff0f57ce60bf25035a32e9e3a 504 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 125 284 1.2E-28 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS16825 ad7136cff0f57ce60bf25035a32e9e3a 504 Gene3D G3DSA:1.10.287.950 3 91 0.16 T 29-03-2018 CVS48_RS16825 ad7136cff0f57ce60bf25035a32e9e3a 504 Gene3D G3DSA:1.10.287.950 92 336 6.6E-36 T 29-03-2018 CVS48_RS15405 01b02f420acd75a91f634a0472d93ecc 408 Gene3D G3DSA:3.40.47.10 4 259 3.9E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15405 01b02f420acd75a91f634a0472d93ecc 408 SMART SM00825 Beta-ketoacyl synthase 4 360 5.2E-10 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CVS48_RS15405 01b02f420acd75a91f634a0472d93ecc 408 SUPERFAMILY SSF53901 215 407 1.15E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15405 01b02f420acd75a91f634a0472d93ecc 408 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 246 9.7E-46 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CVS48_RS15405 01b02f420acd75a91f634a0472d93ecc 408 Gene3D G3DSA:3.40.47.10 260 407 1.9E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15405 01b02f420acd75a91f634a0472d93ecc 408 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 363 4.1E-29 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CVS48_RS15405 01b02f420acd75a91f634a0472d93ecc 408 SUPERFAMILY SSF53901 1 251 1.56E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15405 01b02f420acd75a91f634a0472d93ecc 408 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 SUPERFAMILY SSF47757 9 76 8.63E-7 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 SUPERFAMILY SSF53335 78 256 4.82E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 Gene3D G3DSA:1.10.155.10 3 75 7.5E-8 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 Gene3D G3DSA:3.40.50.150 76 276 7.9E-32 T 29-03-2018 CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 Pfam PF03705 CheR methyltransferase, all-alpha domain 16 64 4.5E-12 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 SMART SM00138 11 274 3.5E-33 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 PRINTS PR00996 Glutamate methyltransferase family signature 33 46 3.1E-23 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 PRINTS PR00996 Glutamate methyltransferase family signature 70 82 3.1E-23 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 PRINTS PR00996 Glutamate methyltransferase family signature 231 254 3.1E-23 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 PRINTS PR00996 Glutamate methyltransferase family signature 138 154 3.1E-23 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 PRINTS PR00996 Glutamate methyltransferase family signature 212 226 3.1E-23 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 PRINTS PR00996 Glutamate methyltransferase family signature 106 126 3.1E-23 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS18100 516a093b2c227d160dce1dddb8ff4ae2 279 Pfam PF01739 CheR methyltransferase, SAM binding domain 78 257 3.4E-36 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 SUPERFAMILY SSF46785 3 113 4.04E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 Gene3D G3DSA:1.10.10.10 1 87 7.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 SUPERFAMILY SSF53850 91 294 1.58E-32 T 29-03-2018 CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.0E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 Gene3D G3DSA:3.40.190.10 183 266 3.6E-14 T 29-03-2018 CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 Gene3D G3DSA:3.40.190.10 92 182 4.5E-22 T 29-03-2018 CVS48_RS17810 fa86dc5ed0a4f4ed9a9f6bc380c29096 296 Pfam PF03466 LysR substrate binding domain 90 294 5.8E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS21270 76c1675dd5b776c94e95c51d25833cd1 305 SUPERFAMILY SSF53850 89 303 4.52E-23 T 29-03-2018 CVS48_RS21270 76c1675dd5b776c94e95c51d25833cd1 305 SUPERFAMILY SSF46785 1 84 2.45E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21270 76c1675dd5b776c94e95c51d25833cd1 305 Gene3D G3DSA:3.40.190.10 93 185 5.7E-11 T 29-03-2018 CVS48_RS21270 76c1675dd5b776c94e95c51d25833cd1 305 Gene3D G3DSA:3.40.190.10 186 274 1.5E-8 T 29-03-2018 CVS48_RS21270 76c1675dd5b776c94e95c51d25833cd1 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.1E-12 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21270 76c1675dd5b776c94e95c51d25833cd1 305 Gene3D G3DSA:1.10.10.10 1 92 3.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21270 76c1675dd5b776c94e95c51d25833cd1 305 Pfam PF03466 LysR substrate binding domain 87 299 1.2E-22 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 Pfam PF02311 AraC-like ligand binding domain 31 111 2.9E-7 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 Gene3D G3DSA:1.10.10.60 213 256 3.4E-9 T 29-03-2018 CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 Gene3D G3DSA:1.10.10.60 155 212 8.5E-11 T 29-03-2018 CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 Pfam PF12833 Helix-turn-helix domain 179 255 4.8E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 210 251 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 SUPERFAMILY SSF51182 32 187 1.51E-7 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 SMART SM00342 173 255 4.5E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 Gene3D G3DSA:2.60.120.10 29 113 4.5E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 224 239 8.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 255 8.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS20405 45bda528b30af4cafb64e7d4c05710a3 259 SUPERFAMILY SSF46689 210 256 2.87E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS23510 62def3c403c39e485e2288537b7111ef 327 Gene3D G3DSA:3.40.190.10 156 295 3.0E-7 T 29-03-2018 CVS48_RS23510 62def3c403c39e485e2288537b7111ef 327 SUPERFAMILY SSF53850 113 288 5.21E-8 T 29-03-2018 CVS48_RS23510 62def3c403c39e485e2288537b7111ef 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 1.5E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23510 62def3c403c39e485e2288537b7111ef 327 PIRSF PIRSF017082 2 326 9.8E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS03840 6220fb5ea9b3293b4fcbecdd7bdc87ff 417 SUPERFAMILY SSF53474 35 394 1.16E-101 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03840 6220fb5ea9b3293b4fcbecdd7bdc87ff 417 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 41 395 2.3E-138 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CVS48_RS03840 6220fb5ea9b3293b4fcbecdd7bdc87ff 417 PIRSF PIRSF000443 10 405 1.3E-144 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CVS48_RS03840 6220fb5ea9b3293b4fcbecdd7bdc87ff 417 Gene3D G3DSA:3.40.50.1820 50 399 2.4E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03840 6220fb5ea9b3293b4fcbecdd7bdc87ff 417 Pfam PF00561 alpha/beta hydrolase fold 70 385 8.7E-36 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS03840 6220fb5ea9b3293b4fcbecdd7bdc87ff 417 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 27 398 48.955 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 SMART SM00873 212 385 1.7E-81 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Gene3D G3DSA:3.30.56.10 1 54 2.1E-12 T 29-03-2018 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 SUPERFAMILY SSF50249 39 198 2.2E-50 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 804 1.5E-221 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Pfam PF01588 Putative tRNA binding domain 45 145 1.6E-26 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Gene3D G3DSA:3.30.930.10 488 692 1.5E-39 T 29-03-2018 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Gene3D G3DSA:2.40.50.140 55 154 5.5E-43 T 29-03-2018 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 SMART SM00896 703 804 1.7E-24 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Gene3D G3DSA:3.30.70.380 700 804 1.2E-15 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Pfam PF03483 B3/4 domain 213 385 2.4E-61 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 798 42.823 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 SUPERFAMILY SSF54991 698 804 1.02E-17 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 SMART SM00874 401 469 1.4E-28 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Pfam PF03147 Ferredoxin-fold anticodon binding domain 703 804 1.7E-20 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Gene3D G3DSA:3.30.56.10 400 473 2.0E-22 T 29-03-2018 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Gene3D G3DSA:3.50.40.10 196 393 6.5E-65 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 SUPERFAMILY SSF46955 402 473 2.38E-18 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 SUPERFAMILY SSF56037 196 390 5.75E-68 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 SUPERFAMILY SSF55681 465 691 3.03E-49 T 29-03-2018 CVS48_RS15185 0794275b82a8d5d2245eca38ca8f1fce 805 Pfam PF03484 tRNA synthetase B5 domain 404 469 9.5E-19 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CVS48_RS06765 58fd064379d9251f8753c187b0afcd3c 358 PIRSF PIRSF001455 12 357 1.3E-107 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CVS48_RS06765 58fd064379d9251f8753c187b0afcd3c 358 SUPERFAMILY SSF56796 9 353 1.83E-111 T 29-03-2018 CVS48_RS06765 58fd064379d9251f8753c187b0afcd3c 358 Gene3D G3DSA:1.20.1090.10 172 358 8.6E-64 T 29-03-2018 CVS48_RS06765 58fd064379d9251f8753c187b0afcd3c 358 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 355 41.11 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CVS48_RS06765 58fd064379d9251f8753c187b0afcd3c 358 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 348 3.4E-116 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CVS48_RS06765 58fd064379d9251f8753c187b0afcd3c 358 Pfam PF01761 3-dehydroquinate synthase 66 323 6.9E-107 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CVS48_RS06765 58fd064379d9251f8753c187b0afcd3c 358 Gene3D G3DSA:3.40.50.1970 7 171 1.8E-48 T 29-03-2018 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SMART SM00387 726 849 1.4E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SUPERFAMILY SSF55785 178 304 2.62E-13 T 29-03-2018 IPR000014 PAS domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Pfam PF00072 Response regulator receiver domain 874 984 1.1E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SUPERFAMILY SSF55785 491 596 5.32E-18 T 29-03-2018 IPR000014 PAS domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Pfam PF08447 PAS fold 507 579 1.7E-11 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Gene3D G3DSA:3.30.450.20 182 310 4.6E-18 T 29-03-2018 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SUPERFAMILY SSF52172 874 995 1.71E-25 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Pfam PF08448 PAS fold 219 307 5.0E-10 T 29-03-2018 IPR013656 PAS fold-4 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Gene3D G3DSA:1.10.287.130 612 681 9.7E-10 T 29-03-2018 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SMART SM00065 34 187 6.7E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SMART SM00091 484 550 2.7E-9 T 29-03-2018 IPR000014 PAS domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SMART SM00091 191 265 1.5 T 29-03-2018 IPR000014 PAS domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Pfam PF00512 His Kinase A (phospho-acceptor) domain 618 683 4.0E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Gene3D G3DSA:3.30.450.40 311 481 3.9E-9 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SUPERFAMILY SSF47384 608 682 6.28E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SUPERFAMILY SSF55781 55 187 3.27E-21 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 488 580 4.8E-13 T 29-03-2018 IPR000014 PAS domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 188 313 1.2E-5 T 29-03-2018 IPR000014 PAS domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Pfam PF13185 GAF domain 35 178 5.3E-17 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 PRINTS PR00344 Bacterial sensor protein C-terminal signature 809 827 1.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 PRINTS PR00344 Bacterial sensor protein C-terminal signature 778 792 1.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 PRINTS PR00344 Bacterial sensor protein C-terminal signature 796 806 1.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 PRINTS PR00344 Bacterial sensor protein C-terminal signature 833 846 1.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SUPERFAMILY SSF55874 675 847 2.23E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Gene3D G3DSA:3.30.565.10 684 848 2.3E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SMART SM00448 872 984 8.1E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Gene3D G3DSA:3.30.450.40 15 181 3.9E-22 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 SMART SM00388 617 685 3.4E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 727 847 3.8E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Gene3D G3DSA:3.30.450.20 484 611 1.3E-21 T 29-03-2018 CVS48_RS19090 40c7f86c87cea59c01e4ea600cbc18ed 1001 Gene3D G3DSA:3.40.50.2300 863 1000 2.0E-25 T 29-03-2018 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 Gene3D G3DSA:3.40.50.10490 3 248 1.2E-90 T 29-03-2018 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 SUPERFAMILY SSF52313 4 228 4.32E-91 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 224 4.2E-97 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 PRINTS PR00395 Ribosomal protein S2 signature 156 173 4.9E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 PRINTS PR00395 Ribosomal protein S2 signature 35 44 4.9E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 PRINTS PR00395 Ribosomal protein S2 signature 173 184 4.9E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 PRINTS PR00395 Ribosomal protein S2 signature 85 102 4.9E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 PRINTS PR00395 Ribosomal protein S2 signature 194 208 4.9E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 PRINTS PR00395 Ribosomal protein S2 signature 4 22 4.9E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 223 38.645 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 4 15 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CVS48_RS17120 c53b09fb6389b7516b3936b19af9a83b 249 Pfam PF00318 Ribosomal protein S2 7 222 1.7E-90 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS27385 797c0c49f94c6a673e8e7feab2717781 354 Gene3D G3DSA:3.40.50.300 1 247 8.4E-78 T 29-03-2018 CVS48_RS27385 797c0c49f94c6a673e8e7feab2717781 354 Pfam PF12857 TOBE-like domain 288 345 3.8E-15 T 29-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 CVS48_RS27385 797c0c49f94c6a673e8e7feab2717781 354 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS27385 797c0c49f94c6a673e8e7feab2717781 354 Pfam PF00005 ABC transporter 18 164 4.2E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS27385 797c0c49f94c6a673e8e7feab2717781 354 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 243 8.4E-121 T 29-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 CVS48_RS27385 797c0c49f94c6a673e8e7feab2717781 354 SUPERFAMILY SSF52540 3 243 5.86E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27385 797c0c49f94c6a673e8e7feab2717781 354 SMART SM00382 27 214 2.9E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22700 69779f12c2692c4c4fa634195dbdb9fc 547 SUPERFAMILY SSF89550 202 264 1.28E-14 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CVS48_RS22700 69779f12c2692c4c4fa634195dbdb9fc 547 SUPERFAMILY SSF89550 299 364 1.28E-14 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CVS48_RS22700 69779f12c2692c4c4fa634195dbdb9fc 547 SUPERFAMILY SSF89550 56 163 1.28E-14 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CVS48_RS22700 69779f12c2692c4c4fa634195dbdb9fc 547 Gene3D G3DSA:3.20.20.140 49 332 7.3E-12 T 29-03-2018 CVS48_RS17985 f9f19e7aa34caf3319ca1ca4ffa539f1 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 502 8.3E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS17985 f9f19e7aa34caf3319ca1ca4ffa539f1 529 Pfam PF00501 AMP-binding enzyme 12 418 4.0E-68 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS17985 f9f19e7aa34caf3319ca1ca4ffa539f1 529 Gene3D G3DSA:3.30.300.30 413 520 1.8E-24 T 29-03-2018 CVS48_RS17985 f9f19e7aa34caf3319ca1ca4ffa539f1 529 Gene3D G3DSA:3.40.50.980 181 328 2.8E-29 T 29-03-2018 CVS48_RS17985 f9f19e7aa34caf3319ca1ca4ffa539f1 529 Gene3D G3DSA:3.40.50.980 2 180 1.6E-31 T 29-03-2018 CVS48_RS17985 f9f19e7aa34caf3319ca1ca4ffa539f1 529 Gene3D G3DSA:2.30.38.10 329 411 1.2E-19 T 29-03-2018 CVS48_RS17985 f9f19e7aa34caf3319ca1ca4ffa539f1 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS17985 f9f19e7aa34caf3319ca1ca4ffa539f1 529 SUPERFAMILY SSF56801 4 513 8.77E-116 T 29-03-2018 CVS48_RS15885 ba335f638a6de6bc3fe512d2cec228db 295 SMART SM00342 227 292 0.0063 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS15885 ba335f638a6de6bc3fe512d2cec228db 295 Gene3D G3DSA:3.40.50.880 1 198 3.0E-60 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS15885 ba335f638a6de6bc3fe512d2cec228db 295 SUPERFAMILY SSF46689 214 260 1.43E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS15885 ba335f638a6de6bc3fe512d2cec228db 295 Pfam PF01965 DJ-1/PfpI family 1 171 1.4E-22 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS15885 ba335f638a6de6bc3fe512d2cec228db 295 SUPERFAMILY SSF52317 1 192 1.57E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS15885 ba335f638a6de6bc3fe512d2cec228db 295 Pfam PF00165 Bacterial regulatory helix-turn-helix proteins, AraC family 220 260 3.3E-9 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS15885 ba335f638a6de6bc3fe512d2cec228db 295 Gene3D G3DSA:1.10.10.60 199 269 7.6E-13 T 29-03-2018 CVS48_RS01585 971bbd1de9e9eb373094d5ff4ceebbb9 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS01585 971bbd1de9e9eb373094d5ff4ceebbb9 549 SUPERFAMILY SSF56801 4 522 8.77E-111 T 29-03-2018 CVS48_RS01585 971bbd1de9e9eb373094d5ff4ceebbb9 549 Gene3D G3DSA:2.30.38.10 326 414 2.8E-20 T 29-03-2018 CVS48_RS01585 971bbd1de9e9eb373094d5ff4ceebbb9 549 Pfam PF00501 AMP-binding enzyme 36 421 8.1E-69 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS01585 971bbd1de9e9eb373094d5ff4ceebbb9 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 511 3.5E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS01585 971bbd1de9e9eb373094d5ff4ceebbb9 549 Gene3D G3DSA:3.30.300.30 416 528 1.3E-23 T 29-03-2018 CVS48_RS01585 971bbd1de9e9eb373094d5ff4ceebbb9 549 Gene3D G3DSA:3.40.50.980 172 325 4.6E-29 T 29-03-2018 CVS48_RS01585 971bbd1de9e9eb373094d5ff4ceebbb9 549 Gene3D G3DSA:3.40.50.980 2 171 3.7E-32 T 29-03-2018 CVS48_RS25315 6bd34057baa239a2cbfa72bebad4140d 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 214 2.2E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS25315 6bd34057baa239a2cbfa72bebad4140d 230 SUPERFAMILY SSF161098 19 208 5.76E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS25315 6bd34057baa239a2cbfa72bebad4140d 230 Gene3D G3DSA:1.10.3720.10 2 223 8.1E-36 T 29-03-2018 CVS48_RS25315 6bd34057baa239a2cbfa72bebad4140d 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 116 1.0E-21 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS12115 fe5f691c979c609ef2177863a0ee3f38 444 ProSitePatterns PS00216 Sugar transport proteins signature 1. 315 332 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS12115 fe5f691c979c609ef2177863a0ee3f38 444 SUPERFAMILY SSF103473 36 435 1.57E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS12115 fe5f691c979c609ef2177863a0ee3f38 444 Gene3D G3DSA:1.20.1250.20 34 249 2.9E-18 T 29-03-2018 CVS48_RS12115 fe5f691c979c609ef2177863a0ee3f38 444 Gene3D G3DSA:1.20.1250.20 250 436 9.2E-9 T 29-03-2018 CVS48_RS12115 fe5f691c979c609ef2177863a0ee3f38 444 Pfam PF07690 Major Facilitator Superfamily 76 389 2.3E-16 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 SUPERFAMILY SSF53850 86 294 1.71E-41 T 29-03-2018 CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 Pfam PF03466 LysR substrate binding domain 90 294 1.1E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 4.8E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 Gene3D G3DSA:3.40.190.10 90 177 4.1E-13 T 29-03-2018 CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 Gene3D G3DSA:3.40.190.10 178 266 8.7E-27 T 29-03-2018 CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 SUPERFAMILY SSF46785 5 89 1.65E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23205 cca1f4bf38ca5132ab276d6b23aec59e 296 Gene3D G3DSA:1.10.10.10 3 88 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15160 66f1021756139ce2250048f33c36966f 83 Pfam PF04380 Membrane fusogenic activity 4 75 1.6E-25 T 29-03-2018 IPR007475 Membrane fusogenic activity CVS48_RS15160 66f1021756139ce2250048f33c36966f 83 Gene3D G3DSA:1.20.120.330 3 83 3.8E-5 T 29-03-2018 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 SUPERFAMILY SSF81653 156 240 3.27E-17 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 SUPERFAMILY SSF56784 472 596 1.85E-36 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 SUPERFAMILY SSF56784 332 356 1.85E-36 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 SUPERFAMILY SSF56784 391 441 1.85E-36 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 Pfam PF00122 E1-E2 ATPase 156 322 2.8E-28 T 29-03-2018 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 Gene3D G3DSA:3.40.1110.10 359 480 1.5E-22 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 Pfam PF00702 haloacid dehalogenase-like hydrolase 340 567 1.6E-33 T 29-03-2018 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 150 377 2.1E-26 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 408 640 1.4E-46 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 187 201 7.9E-24 T 29-03-2018 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 572 7.9E-24 T 29-03-2018 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 344 358 7.9E-24 T 29-03-2018 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 588 7.9E-24 T 29-03-2018 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 500 510 7.9E-24 T 29-03-2018 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 346 352 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 32 713 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 Gene3D G3DSA:1.20.1110.10 51 358 2.7E-24 T 29-03-2018 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 30 717 40.499 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 Gene3D G3DSA:3.40.50.1000 481 612 6.6E-34 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 SUPERFAMILY SSF81665 602 616 8.37E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 SUPERFAMILY SSF81665 51 125 8.37E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS00305 a01a2ba617896a2275e98e3309574940 719 SUPERFAMILY SSF81665 241 338 8.37E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 SMART SM00316 625 695 2.8E-22 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF54211 2 144 5.57E-53 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF00575 S1 RNA binding domain 624 695 4.6E-17 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF55666 458 565 4.35E-28 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF01138 3' exoribonuclease family, domain 1 329 461 1.4E-24 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 1.2E-21 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF03725 3' exoribonuclease family, domain 2 147 205 3.3E-13 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF03725 3' exoribonuclease family, domain 2 466 533 5.0E-5 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:2.40.50.140 630 698 1.1E-21 T 29-03-2018 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:3.30.1370.10 560 629 1.9E-15 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:3.30.230.70 14 233 3.6E-50 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 325 4.6E-18 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 SMART SM00322 557 622 1.8E-13 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF46915 239 326 6.54E-16 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF54211 299 493 9.62E-50 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:3.30.230.70 321 549 7.0E-61 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF55666 145 235 1.68E-30 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 698 30.152 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 PIRSF PIRSF005499 1 720 8.8E-297 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:1.10.10.400 234 320 2.4E-18 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF54791 560 644 2.65E-22 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF00013 KH domain 562 618 2.8E-11 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF50249 618 696 1.57E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS29100 b01d68bb05fc2004df1f1e1f6e960f36 720 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 696 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 SMART SM00316 625 695 2.8E-22 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF54211 2 144 5.57E-53 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF00575 S1 RNA binding domain 624 695 4.6E-17 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF55666 458 565 4.35E-28 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF01138 3' exoribonuclease family, domain 1 329 461 1.4E-24 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 1.2E-21 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF03725 3' exoribonuclease family, domain 2 147 205 3.3E-13 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF03725 3' exoribonuclease family, domain 2 466 533 5.0E-5 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:2.40.50.140 630 698 1.1E-21 T 29-03-2018 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:3.30.1370.10 560 629 1.9E-15 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:3.30.230.70 14 233 3.6E-50 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 325 4.6E-18 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 SMART SM00322 557 622 1.8E-13 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF46915 239 326 6.54E-16 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF54211 299 493 9.62E-50 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:3.30.230.70 321 549 7.0E-61 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF55666 145 235 1.68E-30 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 698 30.152 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 PIRSF PIRSF005499 1 720 8.8E-297 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Gene3D G3DSA:1.10.10.400 234 320 2.4E-18 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF54791 560 644 2.65E-22 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 Pfam PF00013 KH domain 562 618 2.8E-11 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 SUPERFAMILY SSF50249 618 696 1.57E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS00045 b01d68bb05fc2004df1f1e1f6e960f36 720 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 696 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 SUPERFAMILY SSF55347 137 302 2.94E-53 T 29-03-2018 CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 SUPERFAMILY SSF51735 1 158 1.23E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 Pfam PF01842 ACT domain 354 418 6.8E-15 T 29-03-2018 IPR002912 ACT domain CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 Gene3D G3DSA:3.30.360.10 158 298 1.2E-53 T 29-03-2018 CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 7.3E-18 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 PIRSF PIRSF000098 1 433 3.3E-163 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 Pfam PF00742 Homoserine dehydrogenase 137 315 2.9E-65 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 Gene3D G3DSA:3.30.70.260 350 429 1.6E-18 T 29-03-2018 CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 Gene3D G3DSA:3.40.50.720 1 157 1.3E-32 T 29-03-2018 CVS48_RS26700 8ca0be896353be93604e28051bb2cba9 434 SUPERFAMILY SSF55021 353 422 1.04E-14 T 29-03-2018 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 932 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 Gene3D G3DSA:3.40.50.300 37 84 1.9E-4 T 29-03-2018 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 947 22.044 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 ProSitePatterns PS00211 ABC transporters family signature. 837 851 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 Gene3D G3DSA:3.30.190.20 128 247 5.5E-40 T 29-03-2018 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 Gene3D G3DSA:3.40.50.300 1 36 5.9E-9 T 29-03-2018 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 SUPERFAMILY SSF52540 622 916 8.04E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 SUPERFAMILY SSF52540 5 205 7.72E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 SUPERFAMILY SSF52540 438 577 7.72E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 Gene3D G3DSA:3.40.50.300 618 952 4.3E-55 T 29-03-2018 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 Gene3D G3DSA:3.40.50.300 434 613 8.0E-21 T 29-03-2018 CVS48_RS06780 a0b4d5e89939184d858cfbb861ea4229 953 Gene3D G3DSA:1.10.8.280 286 403 8.9E-34 T 29-03-2018 CVS48_RS03055 7e7109feee9d1b00681e21848d5114b6 183 PIRSF PIRSF016183 3 183 1.0E-60 T 29-03-2018 IPR006839 Ribosome-associated, YjgA CVS48_RS03055 7e7109feee9d1b00681e21848d5114b6 183 Gene3D G3DSA:1.10.60.30 107 182 8.4E-22 T 29-03-2018 CVS48_RS03055 7e7109feee9d1b00681e21848d5114b6 183 SUPERFAMILY SSF158710 31 181 2.09E-42 T 29-03-2018 IPR023153 PSPTO4464-like domain CVS48_RS03055 7e7109feee9d1b00681e21848d5114b6 183 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 11 183 21.427 T 29-03-2018 IPR006839 Ribosome-associated, YjgA CVS48_RS03055 7e7109feee9d1b00681e21848d5114b6 183 Pfam PF04751 Protein of unknown function (DUF615) 21 179 5.0E-51 T 29-03-2018 IPR006839 Ribosome-associated, YjgA CVS48_RS03055 7e7109feee9d1b00681e21848d5114b6 183 Gene3D G3DSA:1.10.60.30 33 102 3.2E-25 T 29-03-2018 CVS48_RS00480 7602c68580e094881a93dce637d6b856 645 Pfam PF00589 Phage integrase family 215 392 4.9E-16 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS00480 7602c68580e094881a93dce637d6b856 645 Gene3D G3DSA:1.10.443.10 212 402 4.2E-19 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS00480 7602c68580e094881a93dce637d6b856 645 Gene3D G3DSA:1.10.150.130 89 211 2.7E-15 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CVS48_RS00480 7602c68580e094881a93dce637d6b856 645 SUPERFAMILY SSF56349 100 402 4.71E-47 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS00480 7602c68580e094881a93dce637d6b856 645 Pfam PF13356 Arm DNA-binding domain 7 88 2.8E-16 T 29-03-2018 IPR025166 Integrase, DNA-binding domain CVS48_RS24775 65f5344ddaf57b4fad69c2ec6f09eec1 605 Gene3D G3DSA:4.10.1070.10 519 598 1.0E-8 T 29-03-2018 CVS48_RS24775 65f5344ddaf57b4fad69c2ec6f09eec1 605 Gene3D G3DSA:3.90.1340.10 427 518 1.5E-5 T 29-03-2018 IPR011083 Phage tail collar domain CVS48_RS24775 65f5344ddaf57b4fad69c2ec6f09eec1 605 SUPERFAMILY SSF88874 470 599 8.37E-10 T 29-03-2018 CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Pfam PF13426 PAS domain 169 271 6.7E-13 T 29-03-2018 IPR000014 PAS domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 SUPERFAMILY SSF55781 295 446 5.67E-23 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Pfam PF13185 GAF domain 291 434 2.3E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 SUPERFAMILY SSF55785 168 271 4.71E-14 T 29-03-2018 IPR000014 PAS domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 SMART SM00052 616 862 3.3E-109 T 29-03-2018 IPR001633 EAL domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 SUPERFAMILY SSF55785 46 143 2.62E-13 T 29-03-2018 IPR000014 PAS domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 SMART SM00065 292 443 1.9E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Gene3D G3DSA:3.30.70.270 443 613 6.6E-67 T 29-03-2018 CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Gene3D G3DSA:3.30.450.20 149 281 2.6E-17 T 29-03-2018 CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Gene3D G3DSA:3.40.50.10600 35 148 1.5E-15 T 29-03-2018 CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 SUPERFAMILY SSF55073 451 607 2.2E-52 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 165 274 1.2E-8 T 29-03-2018 IPR000014 PAS domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Pfam PF00990 Diguanylate cyclase, GGDEF domain 446 602 1.5E-50 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 SUPERFAMILY SSF141868 622 869 3.53E-83 T 29-03-2018 IPR001633 EAL domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Pfam PF08447 PAS fold 57 140 2.3E-6 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Pfam PF00563 EAL domain 622 857 1.4E-70 T 29-03-2018 IPR001633 EAL domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Gene3D G3DSA:3.30.450.40 282 442 1.7E-21 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 PIRSF PIRSF005925 147 870 3.5E-272 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 SMART SM00267 435 606 2.5E-72 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 444 604 1.8E-45 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 SMART SM00091 158 225 3.3E-4 T 29-03-2018 IPR000014 PAS domain CVS48_RS03435 315ac95e6d2409c65e66d831285b2775 870 Gene3D G3DSA:3.20.20.450 614 870 5.5E-96 T 29-03-2018 IPR001633 EAL domain CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 Pfam PF00580 UvrD/REP helicase N-terminal domain 21 460 3.1E-42 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 Gene3D G3DSA:3.40.50.300 468 901 1.2E-29 T 29-03-2018 CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 Pfam PF13361 UvrD-like helicase C-terminal domain 792 888 4.6E-12 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 Gene3D G3DSA:3.90.320.10 902 1152 3.8E-11 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 Pfam PF12705 PD-(D/E)XK nuclease superfamily 991 1146 3.1E-5 T 29-03-2018 CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 SUPERFAMILY SSF52540 690 834 4.41E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 SUPERFAMILY SSF52540 111 170 4.41E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 SUPERFAMILY SSF52540 348 640 4.41E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 SUPERFAMILY SSF52540 868 906 4.41E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 SUPERFAMILY SSF52540 9 76 4.41E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 Gene3D G3DSA:3.40.50.300 7 466 2.0E-42 T 29-03-2018 CVS48_RS13715 cc63d28a3a1095c40aad345f23294e99 1157 SUPERFAMILY SSF52980 991 1145 4.61E-8 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CVS48_RS07705 caaac93409d51206953f31f9ccbeaf7f 311 Gene3D G3DSA:3.30.950.10 139 257 1.2E-34 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS07705 caaac93409d51206953f31f9ccbeaf7f 311 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 30 233 2.8E-30 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS07705 caaac93409d51206953f31f9ccbeaf7f 311 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 30 254 33.1 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS07705 caaac93409d51206953f31f9ccbeaf7f 311 PIRSF PIRSF005917 18 309 2.7E-94 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS07705 caaac93409d51206953f31f9ccbeaf7f 311 SUPERFAMILY SSF53790 30 251 2.75E-73 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS07705 caaac93409d51206953f31f9ccbeaf7f 311 Gene3D G3DSA:3.40.1010.10 28 138 1.3E-36 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS07705 caaac93409d51206953f31f9ccbeaf7f 311 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 31 304 1.4E-68 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS07705 caaac93409d51206953f31f9ccbeaf7f 311 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 108 119 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS13655 3d71bfac3c829268748fdaf62d529b3b 265 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 11 236 4.5E-57 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CVS48_RS13655 3d71bfac3c829268748fdaf62d529b3b 265 SUPERFAMILY SSF56601 5 251 4.83E-61 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS13655 3d71bfac3c829268748fdaf62d529b3b 265 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 43 54 3.1E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CVS48_RS13655 3d71bfac3c829268748fdaf62d529b3b 265 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 120 133 3.1E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CVS48_RS13655 3d71bfac3c829268748fdaf62d529b3b 265 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 93 110 3.1E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CVS48_RS13655 3d71bfac3c829268748fdaf62d529b3b 265 Gene3D G3DSA:3.40.710.10 2 263 2.0E-48 T 29-03-2018 CVS48_RS14740 02e6633645ced063ebc6a3b9381722f3 300 Pfam PF01145 SPFH domain / Band 7 family 24 196 3.9E-25 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS14740 02e6633645ced063ebc6a3b9381722f3 300 PIRSF PIRSF005651 1 293 1.4E-86 T 29-03-2018 IPR010200 HflC GO:0016021|GO:0052547 CVS48_RS14740 02e6633645ced063ebc6a3b9381722f3 300 TIGRFAM TIGR01932 hflC: HflC protein 144 285 6.7E-45 T 29-03-2018 IPR010200 HflC GO:0016021|GO:0052547 CVS48_RS14740 02e6633645ced063ebc6a3b9381722f3 300 SUPERFAMILY SSF117892 54 191 1.28E-24 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS14740 02e6633645ced063ebc6a3b9381722f3 300 SMART SM00244 20 185 1.8E-27 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS24790 7dd8bdfaae59d075b7f631d616db7893 134 Gene3D G3DSA:3.10.450.40 3 118 3.4E-10 T 29-03-2018 CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 SUPERFAMILY SSF46785 4 89 6.74E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 5.8E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 Gene3D G3DSA:3.40.190.10 90 179 9.8E-14 T 29-03-2018 CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 Gene3D G3DSA:1.10.10.10 1 85 1.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 Gene3D G3DSA:3.40.190.10 180 260 1.5E-7 T 29-03-2018 CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 SUPERFAMILY SSF53850 89 289 1.25E-26 T 29-03-2018 CVS48_RS02775 695d087503467c4e61e28e5bebfad586 293 Pfam PF03466 LysR substrate binding domain 89 286 1.6E-23 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Pfam PF02769 AIR synthase related protein, C-terminal domain 854 1016 1.7E-13 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Pfam PF02769 AIR synthase related protein, C-terminal domain 447 604 2.8E-26 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Gene3D G3DSA:3.30.1330.10 642 840 8.2E-21 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Gene3D G3DSA:3.30.1330.10 229 439 1.2E-44 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Gene3D G3DSA:3.30.1330.10 193 228 2.4E-4 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 SUPERFAMILY SSF55326 231 437 7.67E-56 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 4 1349 20.467 T 29-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1091 1348 3.3E-99 T 29-03-2018 CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 SUPERFAMILY SSF56042 852 1084 6.28E-49 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 9 1348 0.0 T 29-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 SUPERFAMILY SSF52317 1088 1348 2.29E-86 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 SUPERFAMILY SSF109736 166 230 8.76E-21 T 29-03-2018 CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Gene3D G3DSA:3.90.650.10 847 1047 8.7E-35 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Gene3D G3DSA:3.90.650.10 440 631 3.3E-28 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 SMART SM01211 1091 1348 7.1E-137 T 29-03-2018 CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 SUPERFAMILY SSF55326 650 843 6.02E-64 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 SUPERFAMILY SSF56042 443 683 4.19E-47 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 Gene3D G3DSA:3.40.50.880 1090 1349 1.8E-29 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS21295 5878ac420d899b7f3a5ebf2a41414ad5 1349 SUPERFAMILY SSF82697 5 160 7.85E-44 T 29-03-2018 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 SUPERFAMILY SSF109604 356 501 5.34E-12 T 29-03-2018 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 5 710 21.822 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 Gene3D G3DSA:1.10.730.10 598 707 4.6E-10 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 7 710 7.3E-164 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 8 575 4.7E-174 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 54 66 5.3E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 9 22 5.3E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 260 275 5.3E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 333 349 5.3E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 409 428 5.3E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01955 9fbb71092a28b8a68df4c11cbd0b2650 712 Pfam PF05746 DALR anticodon binding domain 605 703 8.2E-6 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CVS48_RS08375 16f44e3d6a72fb560d54075cb9dd5dfa 568 SUPERFAMILY SSF52540 119 521 6.21E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08375 16f44e3d6a72fb560d54075cb9dd5dfa 568 Pfam PF00437 Type II/IV secretion system protein 125 416 5.2E-40 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS08375 16f44e3d6a72fb560d54075cb9dd5dfa 568 Gene3D G3DSA:3.40.50.300 229 529 1.3E-28 T 29-03-2018 CVS48_RS08375 16f44e3d6a72fb560d54075cb9dd5dfa 568 Gene3D G3DSA:3.30.450.90 87 226 1.4E-22 T 29-03-2018 CVS48_RS19730 4b52747786faef62af1d46bc481bac93 249 SUPERFAMILY SSF51695 12 246 1.78E-62 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CVS48_RS19730 4b52747786faef62af1d46bc481bac93 249 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 16 242 3.6E-38 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CVS48_RS19730 4b52747786faef62af1d46bc481bac93 249 Gene3D G3DSA:3.20.20.190 7 249 2.8E-60 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CVS48_RS27855 6f41e0215a2f960522b3291618189d4f 685 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 15 642 6.1E-212 T 29-03-2018 IPR004814 Oligopeptide transporter OPT CVS48_RS27855 6f41e0215a2f960522b3291618189d4f 685 Gene3D G3DSA:3.40.50.2000 414 612 0.0013 T 29-03-2018 CVS48_RS27855 6f41e0215a2f960522b3291618189d4f 685 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 6 638 5.2E-112 T 29-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CVS48_RS27855 6f41e0215a2f960522b3291618189d4f 685 Pfam PF03169 OPT oligopeptide transporter protein 15 640 5.6E-107 T 29-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 Gene3D G3DSA:3.40.50.720 6 50 0.0042 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 Gene3D G3DSA:3.40.50.720 160 325 1.5E-35 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 Gene3D G3DSA:1.10.287.990 51 104 5.1E-23 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 3.5E-29 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 3.5E-29 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.5E-29 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 3.5E-29 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 3.5E-29 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.0E-67 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 2.0E-67 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 2.0E-67 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 2.0E-67 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 2.0E-67 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 2.0E-67 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 2.0E-67 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.0E-67 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 2.0E-67 T 29-03-2018 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 Gene3D G3DSA:3.30.390.30 326 452 2.5E-40 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 SUPERFAMILY SSF51905 5 367 8.07E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 446 1.7E-36 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 317 2.1E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 SUPERFAMILY SSF55424 335 447 1.12E-37 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS15595 4e35fe21d1fe67351f1439dca94b6004 452 PIRSF PIRSF000350 2 443 7.0E-82 T 29-03-2018 CVS48_RS24115 846f8d849a89a6fa8cb2daa693c0173d 363 Pfam PF09375 Imelysin 46 340 1.8E-39 T 29-03-2018 IPR018976 Peptidase M75, Imelysin CVS48_RS10910 9ba1d42b60eb7f691c88c974ee7ddb00 394 Pfam PF07690 Major Facilitator Superfamily 29 353 4.7E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS10910 9ba1d42b60eb7f691c88c974ee7ddb00 394 SUPERFAMILY SSF103473 13 386 2.49E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS10910 9ba1d42b60eb7f691c88c974ee7ddb00 394 Gene3D G3DSA:1.20.1250.20 15 206 1.6E-24 T 29-03-2018 CVS48_RS10910 9ba1d42b60eb7f691c88c974ee7ddb00 394 Gene3D G3DSA:1.20.1250.20 207 389 2.2E-7 T 29-03-2018 CVS48_RS14970 b7d17ec000980dc8bce7699b62aec836 358 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 352 1.0E-149 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CVS48_RS14970 b7d17ec000980dc8bce7699b62aec836 358 SMART SM01329 4 353 3.0E-208 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CVS48_RS14970 b7d17ec000980dc8bce7699b62aec836 358 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 51.625 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CVS48_RS14970 b7d17ec000980dc8bce7699b62aec836 358 Gene3D G3DSA:3.40.718.10 1 358 4.6E-125 T 29-03-2018 CVS48_RS14970 b7d17ec000980dc8bce7699b62aec836 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CVS48_RS14970 b7d17ec000980dc8bce7699b62aec836 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 4.5E-133 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CVS48_RS14970 b7d17ec000980dc8bce7699b62aec836 358 SUPERFAMILY SSF53659 1 357 7.2E-123 T 29-03-2018 CVS48_RS25325 a4d17213afd10f1f3948dbf32ebe495a 249 Pfam PF00005 ABC transporter 26 174 6.6E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS25325 a4d17213afd10f1f3948dbf32ebe495a 249 PIRSF PIRSF039085 3 249 6.3E-98 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS25325 a4d17213afd10f1f3948dbf32ebe495a 249 Gene3D G3DSA:3.40.50.300 1 248 4.4E-74 T 29-03-2018 CVS48_RS25325 a4d17213afd10f1f3948dbf32ebe495a 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS25325 a4d17213afd10f1f3948dbf32ebe495a 249 SMART SM00382 35 230 1.5E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS25325 a4d17213afd10f1f3948dbf32ebe495a 249 SUPERFAMILY SSF52540 5 244 1.73E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22005 b765a7a75fd1a21a9a0fd23cd72eae2c 67 Gene3D G3DSA:2.40.50.140 1 67 1.8E-27 T 29-03-2018 CVS48_RS22005 b765a7a75fd1a21a9a0fd23cd72eae2c 67 PIRSF PIRSF002599 1 67 3.5E-23 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CVS48_RS22005 b765a7a75fd1a21a9a0fd23cd72eae2c 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 7.0E-29 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS22005 b765a7a75fd1a21a9a0fd23cd72eae2c 67 PRINTS PR00050 Cold shock protein signature 4 19 1.8E-14 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS22005 b765a7a75fd1a21a9a0fd23cd72eae2c 67 PRINTS PR00050 Cold shock protein signature 40 58 1.8E-14 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS22005 b765a7a75fd1a21a9a0fd23cd72eae2c 67 PRINTS PR00050 Cold shock protein signature 25 34 1.8E-14 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS22005 b765a7a75fd1a21a9a0fd23cd72eae2c 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CVS48_RS22005 b765a7a75fd1a21a9a0fd23cd72eae2c 67 SUPERFAMILY SSF50249 1 66 6.37E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS22005 b765a7a75fd1a21a9a0fd23cd72eae2c 67 SMART SM00357 3 67 1.2E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CVS48_RS23040 c661c6a515408d6c4edca4478318bd69 414 Gene3D G3DSA:2.130.10.10 195 413 5.1E-28 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS23040 c661c6a515408d6c4edca4478318bd69 414 Gene3D G3DSA:2.130.10.10 33 191 2.1E-11 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS23040 c661c6a515408d6c4edca4478318bd69 414 Pfam PF10282 Lactonase, 7-bladed beta-propeller 54 413 2.1E-95 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CVS48_RS23040 c661c6a515408d6c4edca4478318bd69 414 SUPERFAMILY SSF51004 93 410 3.79E-39 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CVS48_RS13365 91a4480d70e1c9c770259daf7ee5bd1d 257 SUPERFAMILY SSF55781 80 252 1.24E-40 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13365 91a4480d70e1c9c770259daf7ee5bd1d 257 Gene3D G3DSA:1.10.10.10 1 70 2.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13365 91a4480d70e1c9c770259daf7ee5bd1d 257 Pfam PF01614 Bacterial transcriptional regulator 130 251 2.2E-22 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS13365 91a4480d70e1c9c770259daf7ee5bd1d 257 Pfam PF09339 IclR helix-turn-helix domain 11 60 8.3E-17 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS13365 91a4480d70e1c9c770259daf7ee5bd1d 257 SUPERFAMILY SSF46785 10 77 2.48E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13365 91a4480d70e1c9c770259daf7ee5bd1d 257 SMART SM00346 9 99 7.3E-22 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS13365 91a4480d70e1c9c770259daf7ee5bd1d 257 Gene3D G3DSA:3.30.450.40 78 257 1.6E-39 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS04285 b1bf4a6b2f598ffc2b33ac62ef634b43 353 Gene3D G3DSA:3.30.1330.10 3 167 5.8E-33 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS04285 b1bf4a6b2f598ffc2b33ac62ef634b43 353 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 348 7.3E-30 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS04285 b1bf4a6b2f598ffc2b33ac62ef634b43 353 Pfam PF00586 AIR synthase related protein, N-terminal domain 55 162 3.6E-19 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS04285 b1bf4a6b2f598ffc2b33ac62ef634b43 353 SUPERFAMILY SSF55326 12 166 1.64E-39 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS04285 b1bf4a6b2f598ffc2b33ac62ef634b43 353 PIRSF PIRSF036407 6 352 1.6E-118 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CVS48_RS04285 b1bf4a6b2f598ffc2b33ac62ef634b43 353 TIGRFAM TIGR00476 selD: selenide, water dikinase 12 321 7.8E-134 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CVS48_RS04285 b1bf4a6b2f598ffc2b33ac62ef634b43 353 SUPERFAMILY SSF56042 169 348 9.42E-49 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS04285 b1bf4a6b2f598ffc2b33ac62ef634b43 353 Gene3D G3DSA:3.90.650.10 169 352 2.0E-44 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS04285 b1bf4a6b2f598ffc2b33ac62ef634b43 353 Hamap MF_00625 Selenide, water dikinase [selD]. 10 353 44.583 T 29-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CVS48_RS05185 6f5138412d80e81468ddf4d25e474a7f 462 Gene3D G3DSA:1.20.810.10 15 456 6.5E-166 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CVS48_RS05185 6f5138412d80e81468ddf4d25e474a7f 462 SUPERFAMILY SSF81342 15 288 2.67E-96 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CVS48_RS05185 6f5138412d80e81468ddf4d25e474a7f 462 SUPERFAMILY SSF81648 290 334 1.07E-9 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CVS48_RS05185 6f5138412d80e81468ddf4d25e474a7f 462 Pfam PF00033 Cytochrome b/b6/petB 31 219 6.8E-68 T 29-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CVS48_RS05185 6f5138412d80e81468ddf4d25e474a7f 462 PIRSF PIRSF038885 343 462 7.8E-24 T 29-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 CVS48_RS05185 6f5138412d80e81468ddf4d25e474a7f 462 PIRSF PIRSF038885 4 345 9.4E-133 T 29-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 CVS48_RS05185 6f5138412d80e81468ddf4d25e474a7f 462 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 286 434 1.4E-42 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CVS48_RS05185 6f5138412d80e81468ddf4d25e474a7f 462 SUPERFAMILY SSF81648 355 447 6.28E-20 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CVS48_RS05420 614c53c56856e594e26a024524e443eb 351 SUPERFAMILY SSF52540 4 243 1.64E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05420 614c53c56856e594e26a024524e443eb 351 Gene3D G3DSA:2.40.50.100 234 283 0.0045 T 29-03-2018 CVS48_RS05420 614c53c56856e594e26a024524e443eb 351 Pfam PF00005 ABC transporter 20 161 6.9E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05420 614c53c56856e594e26a024524e443eb 351 Gene3D G3DSA:3.40.50.300 1 233 3.8E-77 T 29-03-2018 CVS48_RS05420 614c53c56856e594e26a024524e443eb 351 SUPERFAMILY SSF50331 236 345 1.14E-21 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS05420 614c53c56856e594e26a024524e443eb 351 Gene3D G3DSA:2.40.50.140 284 331 1.3E-13 T 29-03-2018 CVS48_RS05420 614c53c56856e594e26a024524e443eb 351 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05420 614c53c56856e594e26a024524e443eb 351 Pfam PF08402 TOBE domain 271 339 1.3E-12 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS05420 614c53c56856e594e26a024524e443eb 351 SMART SM00382 28 211 3.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS09035 d1038c5025c7fc00ce8b717b630ef8c9 335 Pfam PF09084 NMT1/THI5 like 51 261 2.0E-48 T 29-03-2018 IPR015168 SsuA/THI5-like CVS48_RS09035 d1038c5025c7fc00ce8b717b630ef8c9 335 Gene3D G3DSA:3.40.190.10 144 332 2.3E-27 T 29-03-2018 CVS48_RS09035 d1038c5025c7fc00ce8b717b630ef8c9 335 SUPERFAMILY SSF53850 54 268 2.05E-38 T 29-03-2018 CVS48_RS09035 d1038c5025c7fc00ce8b717b630ef8c9 335 Gene3D G3DSA:3.40.190.10 34 143 2.7E-8 T 29-03-2018 CVS48_RS17180 51eb6830e283d39374af52188edd8792 264 Gene3D G3DSA:2.160.10.10 2 193 3.3E-43 T 29-03-2018 CVS48_RS17180 51eb6830e283d39374af52188edd8792 264 PIRSF PIRSF000456 1 264 2.2E-94 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CVS48_RS17180 51eb6830e283d39374af52188edd8792 264 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 5 261 1.0E-95 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CVS48_RS17180 51eb6830e283d39374af52188edd8792 264 Gene3D G3DSA:1.20.1180.10 194 264 1.1E-21 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CVS48_RS17180 51eb6830e283d39374af52188edd8792 264 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 177 262 2.7E-25 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CVS48_RS17180 51eb6830e283d39374af52188edd8792 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 134 1.2E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS17180 51eb6830e283d39374af52188edd8792 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 16 48 2.3E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS17180 51eb6830e283d39374af52188edd8792 264 SUPERFAMILY SSF51161 5 248 1.29E-75 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS17180 51eb6830e283d39374af52188edd8792 264 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 2 263 44.248 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CVS48_RS14745 acccb270a8e2c953688924631e6f2736 385 PIRSF PIRSF001549 5 345 4.6E-32 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CVS48_RS14745 acccb270a8e2c953688924631e6f2736 385 Pfam PF13393 Histidyl-tRNA synthetase 10 316 4.7E-112 T 29-03-2018 CVS48_RS14745 acccb270a8e2c953688924631e6f2736 385 SUPERFAMILY SSF55681 4 319 1.97E-52 T 29-03-2018 CVS48_RS14745 acccb270a8e2c953688924631e6f2736 385 Gene3D G3DSA:3.30.930.10 16 309 5.1E-40 T 29-03-2018 CVS48_RS14745 acccb270a8e2c953688924631e6f2736 385 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 367 34.726 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CVS48_RS23310 42f55612cc67d0043223c5cfa0ff5c49 252 Gene3D G3DSA:3.40.190.10 21 116 8.6E-15 T 29-03-2018 CVS48_RS23310 42f55612cc67d0043223c5cfa0ff5c49 252 SUPERFAMILY SSF53850 26 251 9.82E-67 T 29-03-2018 CVS48_RS23310 42f55612cc67d0043223c5cfa0ff5c49 252 PIRSF PIRSF004846 2 252 1.1E-76 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CVS48_RS23310 42f55612cc67d0043223c5cfa0ff5c49 252 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 32 248 7.1E-59 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CVS48_RS23310 42f55612cc67d0043223c5cfa0ff5c49 252 Gene3D G3DSA:3.40.190.10 117 213 1.1E-33 T 29-03-2018 CVS48_RS23310 42f55612cc67d0043223c5cfa0ff5c49 252 Pfam PF13531 Bacterial extracellular solute-binding protein 27 250 2.4E-53 T 29-03-2018 CVS48_RS28030 f90d359cfa1e2fbea503f00d79fe23bb 364 Gene3D G3DSA:3.60.70.12 3 362 9.1E-106 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS28030 f90d359cfa1e2fbea503f00d79fe23bb 364 Pfam PF03576 Peptidase family S58 20 344 2.8E-109 T 29-03-2018 IPR005321 Peptidase S58, DmpA CVS48_RS28030 f90d359cfa1e2fbea503f00d79fe23bb 364 SUPERFAMILY SSF56266 12 360 3.92E-99 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS14385 2b7c6fa1d7c92f5c3b0094c6303f805a 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 7.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14385 2b7c6fa1d7c92f5c3b0094c6303f805a 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 7.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14385 2b7c6fa1d7c92f5c3b0094c6303f805a 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 7.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14385 2b7c6fa1d7c92f5c3b0094c6303f805a 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 7.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14385 2b7c6fa1d7c92f5c3b0094c6303f805a 168 SUPERFAMILY SSF46785 24 158 1.32E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14385 2b7c6fa1d7c92f5c3b0094c6303f805a 168 Gene3D G3DSA:1.10.10.10 2 165 5.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14385 2b7c6fa1d7c92f5c3b0094c6303f805a 168 SMART SM00347 45 145 3.8E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14385 2b7c6fa1d7c92f5c3b0094c6303f805a 168 ProSitePatterns PS01117 MarR-type HTH domain signature. 84 118 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CVS48_RS14385 2b7c6fa1d7c92f5c3b0094c6303f805a 168 Pfam PF12802 MarR family 51 108 1.4E-11 T 29-03-2018 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 Gene3D G3DSA:3.30.470.20 289 459 8.9E-19 T 29-03-2018 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 Pfam PF08245 Mur ligase middle domain 486 697 2.8E-14 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 SUPERFAMILY SSF53623 481 715 1.83E-32 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 SUPERFAMILY SSF56059 219 494 1.13E-33 T 29-03-2018 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 Gene3D G3DSA:3.90.190.20 725 865 3.5E-15 T 29-03-2018 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 Gene3D G3DSA:3.30.1490.20 201 288 6.0E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 SUPERFAMILY SSF53244 726 867 5.49E-16 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 219 304 1.9E-6 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 Gene3D G3DSA:3.40.1190.10 469 717 2.6E-45 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS27620 2814ada47529d85956a09cf44b46706b 871 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 7 868 0.0 T 29-03-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 Gene3D G3DSA:3.40.50.970 2 214 1.2E-42 T 29-03-2018 CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 SUPERFAMILY SSF52518 4 212 1.12E-29 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 224 355 8.3E-32 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 201 8.7E-41 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 SUPERFAMILY SSF52518 412 601 1.81E-45 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 SUPERFAMILY SSF52467 185 382 2.31E-43 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 Gene3D G3DSA:3.40.50.1220 215 374 1.3E-40 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 457 476 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 Gene3D G3DSA:3.40.50.970 375 586 2.2E-31 T 29-03-2018 CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 8 618 1.4E-268 T 29-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 CVS48_RS05215 caa34cc006ca511fbb7b13d7b9fc36d7 620 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 575 1.3E-35 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS17365 79884b720437712a22a87b6df1ef1724 154 SUPERFAMILY SSF55729 4 148 1.39E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS17365 79884b720437712a22a87b6df1ef1724 154 Pfam PF00583 Acetyltransferase (GNAT) family 42 143 6.8E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS17365 79884b720437712a22a87b6df1ef1724 154 Gene3D G3DSA:3.40.630.30 1 148 6.0E-28 T 29-03-2018 CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 Pfam PF11638 DnaA N-terminal domain 3 66 5.8E-18 T 29-03-2018 IPR024633 DnaA N-terminal domain CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 Gene3D G3DSA:1.10.1750.10 388 484 4.5E-34 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 SUPERFAMILY SSF52540 149 360 3.17E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 ProSitePatterns PS01008 DnaA protein signature. 443 462 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 SUPERFAMILY SSF48295 381 484 3.14E-36 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 280 307 3.2E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 214 228 3.2E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 182 202 3.2E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 443 462 3.2E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 246 260 3.2E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 Gene3D G3DSA:3.40.50.300 146 313 7.3E-21 T 29-03-2018 CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 394 462 2.3E-31 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 Pfam PF00308 Bacterial dnaA protein 149 366 4.4E-86 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 SMART SM00382 181 315 2.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 483 1.6E-164 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 SMART SM00760 393 462 3.0E-43 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 484 31.658 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CVS48_RS06035 6ff3c355fb4a54231b1b5a317a509fe7 485 Gene3D G3DSA:1.10.8.60 315 387 1.1E-24 T 29-03-2018 CVS48_RS07805 6867a55d5e8a1c0afeebb4f8a4347d5a 584 ProSitePatterns PS00211 ABC transporters family signature. 506 520 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS07805 6867a55d5e8a1c0afeebb4f8a4347d5a 584 Pfam PF00664 ABC transporter transmembrane region 40 286 1.1E-30 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS07805 6867a55d5e8a1c0afeebb4f8a4347d5a 584 Gene3D G3DSA:3.40.50.300 358 584 1.1E-57 T 29-03-2018 CVS48_RS07805 6867a55d5e8a1c0afeebb4f8a4347d5a 584 Gene3D G3DSA:1.20.1560.10 10 348 3.4E-36 T 29-03-2018 CVS48_RS07805 6867a55d5e8a1c0afeebb4f8a4347d5a 584 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 35 576 5.1E-184 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CVS48_RS07805 6867a55d5e8a1c0afeebb4f8a4347d5a 584 Pfam PF00005 ABC transporter 388 534 9.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07805 6867a55d5e8a1c0afeebb4f8a4347d5a 584 SUPERFAMILY SSF90123 20 346 5.76E-49 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS07805 6867a55d5e8a1c0afeebb4f8a4347d5a 584 SUPERFAMILY SSF52540 368 582 1.81E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07805 6867a55d5e8a1c0afeebb4f8a4347d5a 584 SMART SM00382 395 580 3.3E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 189 218 1.5E-11 T 29-03-2018 CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 85 114 7.3E-6 T 29-03-2018 CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 33 62 1.4E-9 T 29-03-2018 CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 137 166 2.0E-9 T 29-03-2018 CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 36 52 4.7E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 143 161 4.7E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 52 66 4.7E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 201 222 4.7E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 Gene3D G3DSA:4.10.510.10 135 180 3.6E-13 T 29-03-2018 CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 SUPERFAMILY SSF50985 18 222 2.62E-49 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 Gene3D G3DSA:3.10.100.10 70 125 8.7E-11 T 29-03-2018 IPR016186 C-type lectin-like/link domain CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 Gene3D G3DSA:3.10.100.10 7 69 2.5E-14 T 29-03-2018 IPR016186 C-type lectin-like/link domain CVS48_RS21520 b4c7266aff3cda2d1e351681c4a12d2f 236 Gene3D G3DSA:3.10.100.10 181 235 9.6E-16 T 29-03-2018 IPR016186 C-type lectin-like/link domain CVS48_RS11845 661469676e1ce39760ef4f5dc6a3ddf0 123 SMART SM00448 2 113 6.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS11845 661469676e1ce39760ef4f5dc6a3ddf0 123 SUPERFAMILY SSF52172 1 117 3.56E-31 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS11845 661469676e1ce39760ef4f5dc6a3ddf0 123 Gene3D G3DSA:3.40.50.2300 1 122 3.5E-29 T 29-03-2018 CVS48_RS11845 661469676e1ce39760ef4f5dc6a3ddf0 123 Pfam PF00072 Response regulator receiver domain 4 113 1.0E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 Gene3D G3DSA:3.30.420.40 1 248 1.8E-89 T 29-03-2018 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 252 9.6E-79 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 368 388 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 Gene3D G3DSA:3.30.420.40 249 506 2.7E-81 T 29-03-2018 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 456 5.6E-63 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 Hamap MF_00186 Glycerol kinase [glpK]. 4 503 56.605 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 SUPERFAMILY SSF53067 255 502 2.16E-82 T 29-03-2018 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 PIRSF PIRSF000538 4 506 5.0E-176 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 6 502 1.8E-215 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CVS48_RS03600 15f000f25d154cf81774078dc1d838da 506 SUPERFAMILY SSF53067 6 255 1.08E-92 T 29-03-2018 CVS48_RS03170 0b49faca78506aabfd95be3fdc589750 437 Pfam PF13719 zinc-ribbon domain 3 38 2.1E-13 T 29-03-2018 IPR011723 Zinc finger/thioredoxin putative CVS48_RS03170 0b49faca78506aabfd95be3fdc589750 437 Pfam PF11906 Protein of unknown function (DUF3426) 283 433 3.5E-46 T 29-03-2018 IPR021834 Protein of unknown function DUF3426 CVS48_RS03170 0b49faca78506aabfd95be3fdc589750 437 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 4 39 4.6E-13 T 29-03-2018 IPR011723 Zinc finger/thioredoxin putative CVS48_RS21730 05abf529da78e7c635057b2489927c18 372 PIRSF PIRSF029171 22 372 1.2E-36 T 29-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CVS48_RS21730 05abf529da78e7c635057b2489927c18 372 Pfam PF12146 Serine aminopeptidase, S33 99 201 1.4E-7 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CVS48_RS21730 05abf529da78e7c635057b2489927c18 372 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 147 177 - T 29-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 CVS48_RS21730 05abf529da78e7c635057b2489927c18 372 SUPERFAMILY SSF53474 68 357 2.01E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21730 05abf529da78e7c635057b2489927c18 372 Gene3D G3DSA:3.40.50.1820 1 371 7.8E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 289 8.1E-21 T 29-03-2018 IPR015246 Formate dehydrogenase, transmembrane CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 Pfam PF13247 4Fe-4S dicluster domain 92 188 7.2E-24 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 289 1.9E-140 T 29-03-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 SUPERFAMILY SSF54862 29 281 2.41E-71 T 29-03-2018 CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 Gene3D G3DSA:3.30.70.20 42 113 1.5E-21 T 29-03-2018 CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 Gene3D G3DSA:3.30.70.20 19 41 0.0021 T 29-03-2018 CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 Gene3D G3DSA:3.30.70.20 114 155 1.7E-16 T 29-03-2018 CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 PIRSF PIRSF036298 1 299 8.1E-152 T 29-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 Gene3D G3DSA:1.20.5.480 249 291 6.6E-20 T 29-03-2018 CVS48_RS04320 b9662375a4d9ecf1b36c270ffcca7013 299 Gene3D G3DSA:3.30.70.20 156 203 1.4E-5 T 29-03-2018 CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 155 1.4E-11 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 Gene3D G3DSA:1.20.140.10 303 468 1.3E-43 T 29-03-2018 CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 33 8.7E-8 T 29-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 477 595 1.4E-23 T 29-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 SUPERFAMILY SSF47203 286 462 1.93E-45 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 Gene3D G3DSA:2.40.110.10 159 270 1.0E-22 T 29-03-2018 CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 453 1.6E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 266 1.2E-15 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 SUPERFAMILY SSF56645 35 267 6.94E-52 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS27410 15933777f865a609784f6bc009cfbe54 608 Gene3D G3DSA:1.10.540.10 29 158 7.6E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS01125 9d0b8426f9b491a3465ec4b5c39dacb2 398 SUPERFAMILY SSF50129 4 190 4.72E-62 T 29-03-2018 IPR011032 GroES-like CVS48_RS01125 9d0b8426f9b491a3465ec4b5c39dacb2 398 Gene3D G3DSA:3.90.180.10 5 183 2.6E-36 T 29-03-2018 CVS48_RS01125 9d0b8426f9b491a3465ec4b5c39dacb2 398 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 144 3.5E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS01125 9d0b8426f9b491a3465ec4b5c39dacb2 398 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 67 81 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS01125 9d0b8426f9b491a3465ec4b5c39dacb2 398 Gene3D G3DSA:3.40.50.720 184 338 8.2E-22 T 29-03-2018 CVS48_RS01125 9d0b8426f9b491a3465ec4b5c39dacb2 398 Pfam PF00107 Zinc-binding dehydrogenase 197 265 4.6E-8 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS01125 9d0b8426f9b491a3465ec4b5c39dacb2 398 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 3 396 2.6E-225 T 29-03-2018 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 CVS48_RS01125 9d0b8426f9b491a3465ec4b5c39dacb2 398 SUPERFAMILY SSF51735 162 356 2.67E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 PRINTS PR00987 Glutamyl-tRNA synthetase signature 85 98 8.3E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 PRINTS PR00987 Glutamyl-tRNA synthetase signature 240 250 8.3E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 PRINTS PR00987 Glutamyl-tRNA synthetase signature 56 68 8.3E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 PRINTS PR00987 Glutamyl-tRNA synthetase signature 70 81 8.3E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 SUPERFAMILY SSF52374 53 380 6.97E-95 T 29-03-2018 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 59 70 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 586 51.349 T 29-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 53 372 3.8E-100 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 375 565 1.5E-48 T 29-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 Gene3D G3DSA:2.40.240.10 379 500 1.7E-45 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 Gene3D G3DSA:2.40.240.10 501 584 3.8E-26 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 Gene3D G3DSA:1.10.1160.10 296 373 2.1E-31 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 Gene3D G3DSA:3.40.50.620 184 295 4.6E-17 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 Gene3D G3DSA:3.40.50.620 53 182 8.7E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 SUPERFAMILY SSF50715 375 585 1.31E-64 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CVS48_RS01475 854c28ca0bb8c5aa2fbf7eba658d89de 589 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 53 587 4.4E-201 T 29-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CVS48_RS01670 01df2543186a26123adc082a69af5956 210 Pfam PF01063 Amino-transferase class IV 5 206 6.9E-33 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CVS48_RS01670 01df2543186a26123adc082a69af5956 210 SUPERFAMILY SSF56752 4 206 4.97E-40 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CVS48_RS01670 01df2543186a26123adc082a69af5956 210 Gene3D G3DSA:3.20.10.10 75 210 1.0E-27 T 29-03-2018 CVS48_RS01670 01df2543186a26123adc082a69af5956 210 Gene3D G3DSA:3.30.470.10 4 74 1.4E-12 T 29-03-2018 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 SUPERFAMILY SSF53822 79 350 9.93E-59 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 ProSitePatterns PS00356 LacI-type HTH domain signature. 22 40 - T 29-03-2018 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 SUPERFAMILY SSF47413 19 77 9.38E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 Gene3D G3DSA:3.40.50.2300 186 351 3.5E-39 T 29-03-2018 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 Pfam PF00356 Bacterial regulatory proteins, lacI family 21 66 1.0E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 Pfam PF13377 Periplasmic binding protein-like domain 185 348 3.8E-33 T 29-03-2018 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 21 31 9.5E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 31 41 9.5E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 Gene3D G3DSA:1.10.10.60 6 31 0.0071 T 29-03-2018 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 Gene3D G3DSA:1.10.260.40 32 71 9.3E-20 T 29-03-2018 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 SMART SM00354 19 89 1.5E-28 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS21685 78222d444d65d5e39d3c961577c5a23e 354 Gene3D G3DSA:3.40.50.2300 72 185 8.7E-31 T 29-03-2018 CVS48_RS21060 8704491825694614f50ebb97d634a85b 285 Gene3D G3DSA:3.40.1440.10 161 282 1.4E-5 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CVS48_RS21060 8704491825694614f50ebb97d634a85b 285 Gene3D G3DSA:1.10.10.10 96 156 0.0073 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21060 8704491825694614f50ebb97d634a85b 285 Gene3D G3DSA:1.10.260.40 1 56 0.03 T 29-03-2018 CVS48_RS21060 8704491825694614f50ebb97d634a85b 285 Gene3D G3DSA:1.10.10.60 57 95 0.028 T 29-03-2018 CVS48_RS20610 67471cf9c1b52937ad75b14729e04f79 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 1.2E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS20610 67471cf9c1b52937ad75b14729e04f79 398 SUPERFAMILY SSF56645 1 243 2.88E-75 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS20610 67471cf9c1b52937ad75b14729e04f79 398 SUPERFAMILY SSF47203 231 398 3.21E-26 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS20610 67471cf9c1b52937ad75b14729e04f79 398 Gene3D G3DSA:1.10.540.10 1 121 4.9E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS20610 67471cf9c1b52937ad75b14729e04f79 398 Gene3D G3DSA:2.40.110.10 122 218 8.1E-35 T 29-03-2018 CVS48_RS20610 67471cf9c1b52937ad75b14729e04f79 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 1.5E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS20610 67471cf9c1b52937ad75b14729e04f79 398 Gene3D G3DSA:1.20.140.10 219 398 5.1E-44 T 29-03-2018 CVS48_RS20610 67471cf9c1b52937ad75b14729e04f79 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 395 1.1E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS12770 bb54fd29183689403c3c8a919204a446 141 Gene3D G3DSA:3.40.50.620 1 141 1.8E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS12770 bb54fd29183689403c3c8a919204a446 141 PRINTS PR01438 Universal stress protein signature 1 19 8.2E-16 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS12770 bb54fd29183689403c3c8a919204a446 141 PRINTS PR01438 Universal stress protein signature 101 113 8.2E-16 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS12770 bb54fd29183689403c3c8a919204a446 141 PRINTS PR01438 Universal stress protein signature 119 141 8.2E-16 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS12770 bb54fd29183689403c3c8a919204a446 141 Pfam PF00582 Universal stress protein family 1 141 1.1E-23 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS12770 bb54fd29183689403c3c8a919204a446 141 SUPERFAMILY SSF52402 1 141 8.29E-27 T 29-03-2018 CVS48_RS20615 481fc374b2e7fd6df117ea411deed0b1 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 108 3.7E-12 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS20615 481fc374b2e7fd6df117ea411deed0b1 377 Gene3D G3DSA:2.40.110.10 115 224 4.1E-25 T 29-03-2018 CVS48_RS20615 481fc374b2e7fd6df117ea411deed0b1 377 Gene3D G3DSA:1.20.140.10 233 360 1.7E-31 T 29-03-2018 CVS48_RS20615 481fc374b2e7fd6df117ea411deed0b1 377 SUPERFAMILY SSF47203 227 371 8.54E-35 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS20615 481fc374b2e7fd6df117ea411deed0b1 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 353 1.3E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS20615 481fc374b2e7fd6df117ea411deed0b1 377 SUPERFAMILY SSF56645 1 223 7.07E-49 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS20615 481fc374b2e7fd6df117ea411deed0b1 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 212 6.0E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS20615 481fc374b2e7fd6df117ea411deed0b1 377 Gene3D G3DSA:1.10.540.10 1 114 1.7E-17 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 PRINTS PR00297 10kDa chaperonin signature 60 72 4.4E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 PRINTS PR00297 10kDa chaperonin signature 81 94 4.4E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 PRINTS PR00297 10kDa chaperonin signature 3 18 4.4E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 PRINTS PR00297 10kDa chaperonin signature 25 46 4.4E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 SUPERFAMILY SSF50129 1 94 3.06E-34 T 29-03-2018 IPR011032 GroES-like CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 7.1E-36 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 Gene3D G3DSA:2.30.33.40 1 95 3.2E-39 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 SMART SM00883 2 94 1.0E-54 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CVS48_RS11165 3c2798b24e7fef82afcbcf74fd48345b 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.637 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CVS48_RS13595 3f7c8afc41eb7404726804bfca1f7b13 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 274 2.1E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13595 3f7c8afc41eb7404726804bfca1f7b13 277 Gene3D G3DSA:1.10.3720.10 2 263 1.1E-36 T 29-03-2018 CVS48_RS13595 3f7c8afc41eb7404726804bfca1f7b13 277 SUPERFAMILY SSF161098 68 255 4.71E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS01965 46a5696038b05b2a4773c93b43ae8647 240 SUPERFAMILY SSF69593 4 235 4.45E-37 T 29-03-2018 CVS48_RS01965 46a5696038b05b2a4773c93b43ae8647 240 SMART SM00563 71 186 2.8E-29 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CVS48_RS01965 46a5696038b05b2a4773c93b43ae8647 240 Gene3D G3DSA:3.40.1130.10 33 239 1.6E-36 T 29-03-2018 CVS48_RS01965 46a5696038b05b2a4773c93b43ae8647 240 Pfam PF01553 Acyltransferase 59 183 3.5E-20 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CVS48_RS16190 a337594dc1124de2c19084bc89f9f757 319 Gene3D G3DSA:3.40.190.10 111 294 8.7E-9 T 29-03-2018 CVS48_RS16190 a337594dc1124de2c19084bc89f9f757 319 PIRSF PIRSF017082 1 319 4.0E-102 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS16190 a337594dc1124de2c19084bc89f9f757 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 310 1.2E-53 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS27025 d96d6b14927f1a1bade67cd87b7c468b 88 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 20 60 4.0E-13 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CVS48_RS27025 d96d6b14927f1a1bade67cd87b7c468b 88 SUPERFAMILY SSF116842 17 80 1.07E-19 T 29-03-2018 CVS48_RS27025 d96d6b14927f1a1bade67cd87b7c468b 88 Gene3D G3DSA:1.10.287.1040 17 80 3.9E-25 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CVS48_RS27025 d96d6b14927f1a1bade67cd87b7c468b 88 PIRSF PIRSF006488 7 88 3.6E-23 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CVS48_RS27025 d96d6b14927f1a1bade67cd87b7c468b 88 Pfam PF02609 Exonuclease VII small subunit 20 70 2.9E-20 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CVS48_RS27025 d96d6b14927f1a1bade67cd87b7c468b 88 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 19 79 14.984 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CVS48_RS27025 d96d6b14927f1a1bade67cd87b7c468b 88 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 19 73 2.6E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CVS48_RS12580 85d91a1542d6c5c28fb855931cfca3ab 262 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS12580 85d91a1542d6c5c28fb855931cfca3ab 262 Gene3D G3DSA:3.40.50.300 1 244 1.0E-52 T 29-03-2018 CVS48_RS12580 85d91a1542d6c5c28fb855931cfca3ab 262 Pfam PF00005 ABC transporter 18 172 1.7E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS12580 85d91a1542d6c5c28fb855931cfca3ab 262 SUPERFAMILY SSF52540 3 236 8.04E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS12580 85d91a1542d6c5c28fb855931cfca3ab 262 SMART SM00382 27 220 9.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05285 a79650e86f5d514b9f4df103da85ebdb 266 SUPERFAMILY SSF46785 22 95 4.19E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05285 a79650e86f5d514b9f4df103da85ebdb 266 Pfam PF01614 Bacterial transcriptional regulator 145 265 4.1E-19 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS05285 a79650e86f5d514b9f4df103da85ebdb 266 Gene3D G3DSA:1.10.10.10 14 90 1.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05285 a79650e86f5d514b9f4df103da85ebdb 266 SUPERFAMILY SSF55781 88 265 4.05E-39 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS05285 a79650e86f5d514b9f4df103da85ebdb 266 SMART SM00346 22 112 3.8E-25 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS05285 a79650e86f5d514b9f4df103da85ebdb 266 Gene3D G3DSA:3.30.450.40 91 266 3.9E-37 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS05285 a79650e86f5d514b9f4df103da85ebdb 266 Pfam PF09339 IclR helix-turn-helix domain 24 74 3.8E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS07160 5946b9c88eb4cb0f4ae115e52f248cdb 268 SUPERFAMILY SSF53067 1 116 1.04E-17 T 29-03-2018 CVS48_RS07160 5946b9c88eb4cb0f4ae115e52f248cdb 268 Gene3D G3DSA:3.30.420.40 90 268 1.1E-42 T 29-03-2018 CVS48_RS07160 5946b9c88eb4cb0f4ae115e52f248cdb 268 SUPERFAMILY SSF53067 123 230 4.66E-22 T 29-03-2018 CVS48_RS07160 5946b9c88eb4cb0f4ae115e52f248cdb 268 Pfam PF03309 Type III pantothenate kinase 2 201 2.4E-45 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CVS48_RS07160 5946b9c88eb4cb0f4ae115e52f248cdb 268 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 264 14.968 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 Gene3D G3DSA:3.40.50.980 243 403 6.3E-33 T 29-03-2018 CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 ProSitePatterns PS00455 Putative AMP-binding domain signature. 238 249 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 Pfam PF00501 AMP-binding enzyme 62 502 2.5E-78 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 Gene3D G3DSA:3.40.50.980 50 242 1.3E-41 T 29-03-2018 CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 Pfam PF13193 AMP-binding enzyme C-terminal domain 511 594 5.7E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 Gene3D G3DSA:2.30.38.10 404 495 3.7E-8 T 29-03-2018 CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 5 629 0.0 T 29-03-2018 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 5 58 3.6E-20 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 Gene3D G3DSA:3.30.300.30 496 608 1.2E-24 T 29-03-2018 CVS48_RS28165 491792efb71f6da7fc0c7cdc929539db 629 SUPERFAMILY SSF56801 5 625 1.24E-152 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF53300 2477 2669 1.78E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF49313 316 390 5.76E-10 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF13519 von Willebrand factor type A domain 2494 2614 1.2E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 399 505 2.1E-21 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 831 937 2.0E-17 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 1263 1371 5.8E-21 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 615 723 4.9E-22 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 1049 1155 6.9E-21 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 184 295 7.2E-20 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 1482 1586 2.5E-21 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 2125 2234 1.2E-18 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 1701 1802 2.3E-21 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.120.640 1917 2018 1.9E-19 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF49313 1812 1901 8.72E-11 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2829 2847 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF49313 1601 1685 1.5E-10 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF05345 Putative Ig domain 757 807 7.3E-7 T 29-03-2018 IPR008009 Putative Ig CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF05345 Putative Ig domain 1409 1456 1.5E-10 T 29-03-2018 IPR008009 Putative Ig CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF05345 Putative Ig domain 329 376 1.9E-10 T 29-03-2018 IPR008009 Putative Ig CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF05345 Putative Ig domain 1625 1672 1.5E-10 T 29-03-2018 IPR008009 Putative Ig CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF05345 Putative Ig domain 1841 1888 1.5E-10 T 29-03-2018 IPR008009 Putative Ig CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF05345 Putative Ig domain 977 1024 1.5E-10 T 29-03-2018 IPR008009 Putative Ig CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF05345 Putative Ig domain 2057 2102 2.0E-9 T 29-03-2018 IPR008009 Putative Ig CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF05345 Putative Ig domain 545 592 7.6E-11 T 29-03-2018 IPR008009 Putative Ig CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF05345 Putative Ig domain 1193 1240 1.5E-10 T 29-03-2018 IPR008009 Putative Ig CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2820 2838 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00327 2489 2688 9.5E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF49313 722 821 1.33E-7 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00736 510 610 1.8E-6 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00736 2019 2121 0.0026 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00736 942 1042 8.5E-8 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00736 1806 1906 7.0E-7 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00736 1590 1690 1.5E-5 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00736 723 825 2.1E-5 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00736 1374 1474 1.6E-6 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00736 294 394 2.1E-5 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SMART SM00736 1158 1258 1.5E-5 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 724 820 5.2E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 1587 1685 5.7E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 2019 2116 2.6E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 938 1037 4.3E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 1372 1469 7.9E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 1156 1253 6.1E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 296 389 5.5E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 2330 2450 0.38 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 1803 1901 2.2E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.40.10 506 605 2.0E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF49313 2041 2116 1.74E-9 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF51120 2808 2940 1.15E-24 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF49313 523 605 8.03E-11 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 2883 2974 5.9E-18 T 29-03-2018 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2838 2856 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2850 2867 0.0036 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2814 2831 0.032 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2732 2743 2.1 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2832 2849 0.0058 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF49313 1380 1469 7.33E-11 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF49313 1169 1253 1.5E-10 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:2.60.220.10 2235 2329 5.3E-29 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 869 941 5.1E-8 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 2254 2344 6.8E-29 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 643 732 3.5E-10 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1722 1806 1.3E-10 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1075 1158 4.3E-10 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 2171 2249 1.7E-9 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 427 510 5.7E-11 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 234 301 5.7E-6 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1290 1373 1.3E-10 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1506 1590 1.4E-10 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1943 2032 6.2E-8 T 29-03-2018 IPR010221 VCBS repeat CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 Gene3D G3DSA:3.40.50.410 2478 2722 1.2E-28 T 29-03-2018 IPR002035 von Willebrand factor, type A CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 PRINTS PR00313 NodO calcium binding signature 2733 2744 5.4E-10 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 PRINTS PR00313 NodO calcium binding signature 2815 2823 5.4E-10 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 PRINTS PR00313 NodO calcium binding signature 2860 2869 5.4E-10 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 PRINTS PR00313 NodO calcium binding signature 2833 2841 5.4E-10 T 29-03-2018 CVS48_RS14930 43823a5ec54cc6449bbed5ce9e315bea 2978 SUPERFAMILY SSF49313 948 1037 5.76E-11 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS04385 8f6d31199288b6b5165ee6f898d2cbb7 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS04385 8f6d31199288b6b5165ee6f898d2cbb7 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS04385 8f6d31199288b6b5165ee6f898d2cbb7 486 Gene3D G3DSA:3.40.309.10 268 455 1.1E-63 T 29-03-2018 CVS48_RS04385 8f6d31199288b6b5165ee6f898d2cbb7 486 SUPERFAMILY SSF53720 7 483 8.51E-156 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS04385 8f6d31199288b6b5165ee6f898d2cbb7 486 Gene3D G3DSA:3.40.605.10 2 267 4.0E-93 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS04385 8f6d31199288b6b5165ee6f898d2cbb7 486 Pfam PF00171 Aldehyde dehydrogenase family 17 482 1.0E-164 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS18275 02bf07ee8808ffeb06a3e9390e766236 289 SUPERFAMILY SSF161098 86 276 1.31E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18275 02bf07ee8808ffeb06a3e9390e766236 289 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 60 4.4E-6 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS18275 02bf07ee8808ffeb06a3e9390e766236 289 Gene3D G3DSA:1.10.3720.10 12 277 4.1E-32 T 29-03-2018 CVS48_RS18275 02bf07ee8808ffeb06a3e9390e766236 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 276 3.4E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.677 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 Pfam PF00334 Nucleoside diphosphate kinase 4 136 1.5E-53 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 SMART SM00562 3 140 9.9E-82 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.4E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.4E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.4E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.4E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 1.4E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 Gene3D G3DSA:3.30.70.141 1 141 1.9E-49 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 SUPERFAMILY SSF54919 1 139 3.27E-55 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CVS48_RS14680 f0a65194ca7b482f11cdc1696a3bebe0 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 29-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS12905 5bd2c4a8de436c3fd5753ca1529661ea 345 Pfam PF04055 Radical SAM superfamily 63 216 1.7E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS12905 5bd2c4a8de436c3fd5753ca1529661ea 345 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 233 323 6.3E-19 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CVS48_RS12905 5bd2c4a8de436c3fd5753ca1529661ea 345 SMART SM00876 233 325 4.8E-46 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CVS48_RS12905 5bd2c4a8de436c3fd5753ca1529661ea 345 SMART SM00729 56 268 1.8E-38 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CVS48_RS12905 5bd2c4a8de436c3fd5753ca1529661ea 345 SUPERFAMILY SSF102114 20 323 1.19E-91 T 29-03-2018 CVS48_RS12905 5bd2c4a8de436c3fd5753ca1529661ea 345 TIGRFAM TIGR00433 bioB: biotin synthase 27 323 7.2E-124 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CVS48_RS12905 5bd2c4a8de436c3fd5753ca1529661ea 345 PIRSF PIRSF001619 5 330 1.7E-132 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CVS48_RS12905 5bd2c4a8de436c3fd5753ca1529661ea 345 Hamap MF_01694 Biotin synthase [bioB]. 18 326 42.281 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CVS48_RS12905 5bd2c4a8de436c3fd5753ca1529661ea 345 Gene3D G3DSA:3.20.20.70 18 328 4.5E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 789 946 1.11E-17 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 2192 2311 6.15E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 3310 3482 4.58E-23 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 2749 2901 4.18E-13 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 2389 2509 2.62E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 3190 3290 5.49E-16 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 1995 2114 4.71E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1895 1934 4.1E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3130 3171 1.6E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3070 3102 9.6E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3461 3500 1.1E-4 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2092 2131 3.4E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3635 3669 6.1E-7 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2880 2913 1.0E-7 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3581 3618 6.0E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 751 795 2.3E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2486 2519 1.9E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1501 1540 6.7E-9 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1121 1162 1.7E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2289 2328 2.5E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1311 1338 8.1E-9 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1698 1738 4.0E-9 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 924 963 1.0E-6 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2683 2722 7.5E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3268 3305 1.1E-7 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 409 524 1.23E-11 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 1598 1721 9.81E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 3511 3604 1.28E-17 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 175 301 1.5E-16 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 519 620 3.14E-19 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 674 778 3.14E-19 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 2969 3092 7.85E-13 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:3.30.1300.30 3660 3760 1.2E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 1381 1515 2.8E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 2766 2906 4.8E-17 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 2580 2697 1.1E-17 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 2374 2500 5.9E-17 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 2172 2303 6.3E-17 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 282 412 3.2E-8 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 180 281 3.8E-18 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 413 496 3.7E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 1775 1909 1.9E-15 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 1149 1328 4.6E-15 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 962 1147 3.8E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 1978 2106 1.6E-17 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 1592 1712 1.8E-16 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF13018 Extended Signal Peptide of Type V secretion system 22 44 2.2E-7 T 29-03-2018 IPR024973 ESPR domain CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 497 556 1.4E-11 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 632 756 7.5E-15 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 557 631 2.4E-13 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 88 179 6.0E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 1791 1918 9.02E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 3297 3485 1.8E-26 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 2908 3082 1.8E-19 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 3608 3655 3.6E-8 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF54523 3645 3760 5.96E-21 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 3614 3655 6.8E-6 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05658 Head domain of trimeric autotransporter adhesin 3536 3562 1.2E-4 T 29-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05658 Head domain of trimeric autotransporter adhesin 200 226 4.1E-4 T 29-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Pfam PF05658 Head domain of trimeric autotransporter adhesin 3198 3223 8.8E-6 T 29-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 1405 1523 1.44E-12 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 1214 1332 1.96E-13 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 1024 1142 3.14E-11 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 SUPERFAMILY SSF101967 2583 2706 1.09E-14 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:1.20.5.170 2304 2373 0.0033 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:1.20.5.170 2107 2171 0.0039 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:1.20.5.170 1910 1977 0.0046 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:1.20.5.170 1329 1380 0.18 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:1.20.5.170 1516 1591 0.0099 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:1.20.5.170 2501 2579 0.015 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:1.20.5.170 3083 3105 0.33 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:1.20.5.170 2698 2765 0.023 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:1.20.5.170 1713 1774 0.0011 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 3106 3164 4.4E-7 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 3166 3296 3.5E-22 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 786 956 3.0E-21 T 29-03-2018 CVS48_RS17695 dbb9d6b8a95c499109e6705b150fcf37 3760 Gene3D G3DSA:2.150.10.10 3490 3607 2.6E-20 T 29-03-2018 CVS48_RS01505 142632f4c865329573c25794176b83bb 125 Gene3D G3DSA:3.40.50.1010 1 120 1.6E-10 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS01505 142632f4c865329573c25794176b83bb 125 SUPERFAMILY SSF88723 1 119 5.61E-13 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 Gene3D G3DSA:3.30.1550.10 3 72 9.5E-34 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 3.1E-24 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.413 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-16 T 29-03-2018 CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 SUPERFAMILY SSF46906 68 141 3.27E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 Gene3D G3DSA:1.10.10.250 73 141 9.5E-24 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 5.7E-29 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 SUPERFAMILY SSF54747 3 73 2.22E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.1E-63 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06255 f967b1addaf976eb984c7ca918490858 143 SMART SM00649 9 141 9.7E-84 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CVS48_RS08770 3e454e15c375a5106253fb827c5818e2 306 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 170 290 3.8E-37 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CVS48_RS08770 3e454e15c375a5106253fb827c5818e2 306 SUPERFAMILY SSF51735 7 169 3.03E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS08770 3e454e15c375a5106253fb827c5818e2 306 SUPERFAMILY SSF48179 169 298 3.97E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS08770 3e454e15c375a5106253fb827c5818e2 306 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 166 7.4E-42 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CVS48_RS08770 3e454e15c375a5106253fb827c5818e2 306 PIRSF PIRSF000103 1 300 3.6E-71 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CVS48_RS08770 3e454e15c375a5106253fb827c5818e2 306 Gene3D G3DSA:1.10.1040.10 177 297 5.7E-27 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS08770 3e454e15c375a5106253fb827c5818e2 306 Gene3D G3DSA:3.40.50.720 1 176 9.0E-33 T 29-03-2018 CVS48_RS25510 dbcb61b1b408a96662fe21bb3ec05784 260 Gene3D G3DSA:3.40.225.10 25 254 1.9E-51 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS25510 dbcb61b1b408a96662fe21bb3ec05784 260 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 34 211 1.0E-38 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS25510 dbcb61b1b408a96662fe21bb3ec05784 260 SMART SM01007 33 211 1.6E-46 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS25510 dbcb61b1b408a96662fe21bb3ec05784 260 SUPERFAMILY SSF53639 25 236 8.44E-65 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS13000 a6ade628e0ddebcc24dcd0438c52d73a 626 SUPERFAMILY SSF82866 412 610 1.44E-40 T 29-03-2018 CVS48_RS13000 a6ade628e0ddebcc24dcd0438c52d73a 626 Pfam PF02355 Protein export membrane protein 435 596 1.2E-18 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CVS48_RS13000 a6ade628e0ddebcc24dcd0438c52d73a 626 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 361 595 2.8E-73 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CVS48_RS13000 a6ade628e0ddebcc24dcd0438c52d73a 626 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 135 601 4.6E-143 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CVS48_RS13000 a6ade628e0ddebcc24dcd0438c52d73a 626 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 616 48.033 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CVS48_RS13000 a6ade628e0ddebcc24dcd0438c52d73a 626 Pfam PF07549 SecD/SecF GG Motif 131 152 4.7E-6 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CVS48_RS13000 a6ade628e0ddebcc24dcd0438c52d73a 626 Gene3D G3DSA:1.20.1640.10 393 608 2.0E-29 T 29-03-2018 CVS48_RS13000 a6ade628e0ddebcc24dcd0438c52d73a 626 Pfam PF13721 SecD export protein N-terminal TM region 1 112 1.9E-34 T 29-03-2018 IPR027398 SecD export protein N-terminal TM domain CVS48_RS15800 ac137146905fcdeb7d17b071d613f85a 224 Gene3D G3DSA:1.20.120.530 78 224 2.5E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS15800 ac137146905fcdeb7d17b071d613f85a 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 1.8E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15800 ac137146905fcdeb7d17b071d613f85a 224 SUPERFAMILY SSF48008 82 215 1.54E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS15800 ac137146905fcdeb7d17b071d613f85a 224 SMART SM00345 17 75 6.7E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15800 ac137146905fcdeb7d17b071d613f85a 224 SMART SM00895 85 209 4.9E-12 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS15800 ac137146905fcdeb7d17b071d613f85a 224 SUPERFAMILY SSF46785 13 79 7.64E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15800 ac137146905fcdeb7d17b071d613f85a 224 Gene3D G3DSA:1.10.10.10 3 77 1.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15800 ac137146905fcdeb7d17b071d613f85a 224 Pfam PF07729 FCD domain 85 207 2.8E-21 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 Pfam PF03466 LysR substrate binding domain 93 300 1.6E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 8.2E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 Gene3D G3DSA:1.10.10.10 2 89 2.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 5.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 5.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 5.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 Gene3D G3DSA:3.40.190.10 96 188 4.2E-19 T 29-03-2018 CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 SUPERFAMILY SSF46785 5 110 1.09E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 Gene3D G3DSA:3.40.190.10 189 271 4.9E-14 T 29-03-2018 CVS48_RS09425 ba224cf5f627ba105e8c0ace5e251cd9 311 SUPERFAMILY SSF53850 96 305 1.97E-35 T 29-03-2018 CVS48_RS11425 9fc4d9587d91ef2fc25da0815b9845dc 241 SUPERFAMILY SSF53474 1 228 7.14E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11425 9fc4d9587d91ef2fc25da0815b9845dc 241 PIRSF PIRSF017388 1 230 9.8E-40 T 29-03-2018 IPR012354 Esterase/lipase GO:0052689 CVS48_RS11425 9fc4d9587d91ef2fc25da0815b9845dc 241 Pfam PF12146 Serine aminopeptidase, S33 11 209 1.9E-14 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CVS48_RS11425 9fc4d9587d91ef2fc25da0815b9845dc 241 Gene3D G3DSA:3.40.50.1820 1 227 6.1E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS09515 b36e2b651a212bc93802431ce5ba586f 290 Pfam PF13560 Helix-turn-helix domain 16 95 1.1E-16 T 29-03-2018 CVS48_RS09515 b36e2b651a212bc93802431ce5ba586f 290 Gene3D G3DSA:1.10.260.40 8 105 2.3E-12 T 29-03-2018 CVS48_RS09515 b36e2b651a212bc93802431ce5ba586f 290 SMART SM00530 22 92 1.4E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS09515 b36e2b651a212bc93802431ce5ba586f 290 SUPERFAMILY SSF47413 39 90 6.26E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS01865 6972c2b0756d550d616705e2bfbd1320 297 Gene3D G3DSA:1.10.10.10 1 85 2.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01865 6972c2b0756d550d616705e2bfbd1320 297 SUPERFAMILY SSF53850 90 293 1.36E-43 T 29-03-2018 CVS48_RS01865 6972c2b0756d550d616705e2bfbd1320 297 SUPERFAMILY SSF46785 1 113 1.22E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01865 6972c2b0756d550d616705e2bfbd1320 297 Pfam PF03466 LysR substrate binding domain 89 292 1.2E-44 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS01865 6972c2b0756d550d616705e2bfbd1320 297 Gene3D G3DSA:3.40.190.10 90 177 2.3E-24 T 29-03-2018 CVS48_RS01865 6972c2b0756d550d616705e2bfbd1320 297 Gene3D G3DSA:3.40.190.10 178 269 2.2E-22 T 29-03-2018 CVS48_RS01865 6972c2b0756d550d616705e2bfbd1320 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 8.2E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05495 7e4174df31c4ad3cf305539ffd59da40 126 Pfam PF13411 MerR HTH family regulatory protein 7 70 8.6E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS05495 7e4174df31c4ad3cf305539ffd59da40 126 Gene3D G3DSA:1.10.1660.10 59 126 8.8E-12 T 29-03-2018 CVS48_RS05495 7e4174df31c4ad3cf305539ffd59da40 126 Gene3D G3DSA:1.10.1660.10 1 58 4.1E-19 T 29-03-2018 CVS48_RS05495 7e4174df31c4ad3cf305539ffd59da40 126 SUPERFAMILY SSF46955 6 118 2.05E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS05495 7e4174df31c4ad3cf305539ffd59da40 126 SMART SM00422 6 73 1.8E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS23360 65a8d4e2498fc1d7259ee791ceb5a793 323 SUPERFAMILY SSF53822 35 284 5.62E-22 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS23360 65a8d4e2498fc1d7259ee791ceb5a793 323 Gene3D G3DSA:3.40.50.2300 27 152 1.2E-22 T 29-03-2018 CVS48_RS23360 65a8d4e2498fc1d7259ee791ceb5a793 323 Gene3D G3DSA:3.40.50.2300 153 286 9.9E-18 T 29-03-2018 CVS48_RS23360 65a8d4e2498fc1d7259ee791ceb5a793 323 Pfam PF04392 ABC transporter substrate binding protein 30 321 2.6E-112 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein CVS48_RS15755 1022f0f9e1aec11d6f8d7129e9208c6c 162 SUPERFAMILY SSF48695 32 149 7.81E-45 T 29-03-2018 IPR011031 Multihaem cytochrome CVS48_RS15755 1022f0f9e1aec11d6f8d7129e9208c6c 162 PIRSF PIRSF006105 1 160 5.8E-53 T 29-03-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB CVS48_RS15755 1022f0f9e1aec11d6f8d7129e9208c6c 162 Gene3D G3DSA:1.10.1130.10 65 131 7.0E-28 T 29-03-2018 CVS48_RS15755 1022f0f9e1aec11d6f8d7129e9208c6c 162 Pfam PF03892 Nitrate reductase cytochrome c-type subunit (NapB) 31 146 6.1E-48 T 29-03-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 SUPERFAMILY SSF53597 5 160 9.97E-57 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 PIRSF PIRSF000194 1 160 2.0E-61 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 PRINTS PR00070 Dihydrofolate reductase signature 30 38 2.2E-16 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 PRINTS PR00070 Dihydrofolate reductase signature 94 108 2.2E-16 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 PRINTS PR00070 Dihydrofolate reductase signature 43 54 2.2E-16 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 PRINTS PR00070 Dihydrofolate reductase signature 16 26 2.2E-16 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 Gene3D G3DSA:3.40.430.10 1 39 5.0E-13 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 Gene3D G3DSA:3.40.430.10 40 160 5.1E-41 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 16 38 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CVS48_RS10650 9f515d9c40e8b2a912d97d2c37509ea4 160 Pfam PF00186 Dihydrofolate reductase 5 160 1.2E-58 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CVS48_RS07505 00b631df2e94fef544091cd8c0925f06 488 SUPERFAMILY SSF52540 296 485 9.02E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07505 00b631df2e94fef544091cd8c0925f06 488 TIGRFAM TIGR03708 poly_P_AMP_trns: polyphosphate:AMP phosphotransferase 2 488 1.0E-199 T 29-03-2018 IPR022489 Polyphosphate:AMP phosphotransferase GO:0006797|GO:0043751 CVS48_RS07505 00b631df2e94fef544091cd8c0925f06 488 SUPERFAMILY SSF52540 43 231 1.75E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07505 00b631df2e94fef544091cd8c0925f06 488 Gene3D G3DSA:3.40.50.300 3 256 4.5E-59 T 29-03-2018 CVS48_RS07505 00b631df2e94fef544091cd8c0925f06 488 Gene3D G3DSA:3.40.50.300 257 488 6.0E-82 T 29-03-2018 CVS48_RS07505 00b631df2e94fef544091cd8c0925f06 488 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 264 487 1.3E-84 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related CVS48_RS07505 00b631df2e94fef544091cd8c0925f06 488 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 12 235 1.3E-41 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 SUPERFAMILY SSF56024 335 502 2.2E-55 T 29-03-2018 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 Pfam PF13090 Polyphosphate kinase C-terminal domain 340 687 5.7E-154 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 SUPERFAMILY SSF56024 511 687 4.49E-68 T 29-03-2018 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 Gene3D G3DSA:1.20.58.310 13 115 9.9E-34 T 29-03-2018 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 SUPERFAMILY SSF140356 9 112 1.18E-33 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 SUPERFAMILY SSF143724 114 319 5.69E-61 T 29-03-2018 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 PIRSF PIRSF015589 5 690 1.4E-262 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 Hamap MF_00347 Polyphosphate kinase [ppk]. 9 691 28.189 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 Pfam PF13089 Polyphosphate kinase N-terminal domain 12 116 1.2E-33 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 Pfam PF02503 Polyphosphate kinase middle domain 125 324 4.3E-57 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 Gene3D G3DSA:3.30.1840.10 116 312 7.4E-59 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 11 687 2.6E-289 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 Gene3D G3DSA:3.30.870.10 331 509 1.4E-20 T 29-03-2018 CVS48_RS13880 2087b50a31600ca4ccecc9ea08c5ad0b 691 Gene3D G3DSA:3.30.870.10 510 690 6.4E-36 T 29-03-2018 CVS48_RS02440 a58686317d295f01ac128f5b86e3cf74 307 SUPERFAMILY SSF54211 3 125 3.49E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS02440 a58686317d295f01ac128f5b86e3cf74 307 Gene3D G3DSA:3.30.230.20 1 127 1.8E-46 T 29-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS02440 a58686317d295f01ac128f5b86e3cf74 307 SUPERFAMILY SSF54211 143 281 7.59E-51 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS02440 a58686317d295f01ac128f5b86e3cf74 307 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 279 3.3E-105 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS02440 a58686317d295f01ac128f5b86e3cf74 307 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3 301 3.8E-120 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS02440 a58686317d295f01ac128f5b86e3cf74 307 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 283 45.292 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS02440 a58686317d295f01ac128f5b86e3cf74 307 Gene3D G3DSA:3.30.1700.10 128 302 6.1E-68 T 29-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 Gene3D G3DSA:1.10.8.60 334 413 2.3E-27 T 29-03-2018 CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 SMART SM00382 186 325 1.5E-25 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 Gene3D G3DSA:3.40.50.300 133 333 5.8E-62 T 29-03-2018 CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 322 1.9E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 102 593 3.6E-239 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 SUPERFAMILY SSF140990 404 602 2.62E-75 T 29-03-2018 CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 SUPERFAMILY SSF52540 146 393 1.08E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 Pfam PF01434 Peptidase family M41 384 592 1.6E-79 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 ProSitePatterns PS00674 AAA-protein family signature. 293 311 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 599 37.296 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CVS48_RS13855 78774bfe0cb07b3774de811b54f37473 630 Pfam PF06480 FtsH Extracellular 10 80 3.0E-6 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CVS48_RS02355 9fb7ab0b5a6080ca400cabaeeb683fab 398 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 382 9.4E-112 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS02355 9fb7ab0b5a6080ca400cabaeeb683fab 398 Pfam PF07687 Peptidase dimerisation domain 187 281 1.8E-12 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS02355 9fb7ab0b5a6080ca400cabaeeb683fab 398 Gene3D G3DSA:3.40.630.10 2 228 1.2E-50 T 29-03-2018 CVS48_RS02355 9fb7ab0b5a6080ca400cabaeeb683fab 398 Gene3D G3DSA:3.40.630.10 246 398 1.3E-22 T 29-03-2018 CVS48_RS02355 9fb7ab0b5a6080ca400cabaeeb683fab 398 SUPERFAMILY SSF55031 184 297 8.11E-32 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS02355 9fb7ab0b5a6080ca400cabaeeb683fab 398 SUPERFAMILY SSF53187 299 395 8.0E-88 T 29-03-2018 CVS48_RS02355 9fb7ab0b5a6080ca400cabaeeb683fab 398 SUPERFAMILY SSF53187 3 198 8.0E-88 T 29-03-2018 CVS48_RS02355 9fb7ab0b5a6080ca400cabaeeb683fab 398 PIRSF PIRSF005962 2 398 1.7E-132 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS02355 9fb7ab0b5a6080ca400cabaeeb683fab 398 Pfam PF01546 Peptidase family M20/M25/M40 74 354 4.2E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 94 107 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 1.1E-47 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 156 179 1.1E-47 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 234 258 1.1E-47 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 75 91 1.1E-47 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 203 224 1.1E-47 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 53 73 1.1E-47 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 PRINTS PR01959 SuhB family inositol monophosphatase signature 130 149 5.0E-13 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 PRINTS PR01959 SuhB family inositol monophosphatase signature 224 236 5.0E-13 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 PRINTS PR01959 SuhB family inositol monophosphatase signature 182 208 5.0E-13 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 SUPERFAMILY SSF56655 19 286 6.02E-74 T 29-03-2018 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 237 251 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 Gene3D G3DSA:3.30.540.10 7 171 2.4E-45 T 29-03-2018 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 Pfam PF00459 Inositol monophosphatase family 20 286 2.1E-58 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS02345 7bc83feb5267f705453b5791a34d3ccc 295 Gene3D G3DSA:3.40.190.80 172 294 2.0E-31 T 29-03-2018 CVS48_RS25025 2b0c47c52685cc2a1e852fa50d70ba27 263 SUPERFAMILY SSF51735 5 260 8.06E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25025 2b0c47c52685cc2a1e852fa50d70ba27 263 Pfam PF00106 short chain dehydrogenase 7 198 1.8E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25025 2b0c47c52685cc2a1e852fa50d70ba27 263 Gene3D G3DSA:3.40.50.720 1 261 2.5E-64 T 29-03-2018 CVS48_RS25025 2b0c47c52685cc2a1e852fa50d70ba27 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.0E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25025 2b0c47c52685cc2a1e852fa50d70ba27 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25025 2b0c47c52685cc2a1e852fa50d70ba27 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.0E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25025 2b0c47c52685cc2a1e852fa50d70ba27 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.0E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25025 2b0c47c52685cc2a1e852fa50d70ba27 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.0E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 SUPERFAMILY SSF52540 30 266 9.99E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 Gene3D G3DSA:3.40.50.300 13 282 8.5E-73 T 29-03-2018 CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 Gene3D G3DSA:3.40.50.300 283 561 9.0E-73 T 29-03-2018 CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 516 542 5.0E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 280 4.2E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 Pfam PF00005 ABC transporter 35 194 1.2E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 Pfam PF00005 ABC transporter 315 464 6.0E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 SMART SM00382 323 514 3.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 SMART SM00382 43 244 1.7E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 SUPERFAMILY SSF52540 289 536 6.05E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10610 8bf23495d35677680f2f99bad2c63071 563 ProSitePatterns PS00211 ABC transporters family signature. 437 451 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 Gene3D G3DSA:3.40.190.10 91 182 7.2E-21 T 29-03-2018 CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 Gene3D G3DSA:3.40.190.10 183 267 1.7E-20 T 29-03-2018 CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 SUPERFAMILY SSF46785 4 114 1.52E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 SUPERFAMILY SSF53850 90 294 8.01E-42 T 29-03-2018 CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 Gene3D G3DSA:1.10.10.10 1 89 2.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.5E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.8E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.8E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.8E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09250 10eab206e1f432923cc784d425f2346e 296 Pfam PF03466 LysR substrate binding domain 90 292 3.7E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS09805 9fcf755a9202758a7497b67fe7fd0618 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 107 2.2E-26 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CVS48_RS09805 9fcf755a9202758a7497b67fe7fd0618 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CVS48_RS09805 9fcf755a9202758a7497b67fe7fd0618 382 SMART SM00922 125 230 2.9E-22 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CVS48_RS09805 9fcf755a9202758a7497b67fe7fd0618 382 Gene3D G3DSA:3.30.390.10 1 97 1.2E-29 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS09805 9fcf755a9202758a7497b67fe7fd0618 382 SUPERFAMILY SSF51604 95 359 7.07E-80 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS09805 9fcf755a9202758a7497b67fe7fd0618 382 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CVS48_RS09805 9fcf755a9202758a7497b67fe7fd0618 382 Gene3D G3DSA:3.20.20.120 98 353 7.3E-77 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS09805 9fcf755a9202758a7497b67fe7fd0618 382 SUPERFAMILY SSF54826 1 112 1.25E-31 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS09805 9fcf755a9202758a7497b67fe7fd0618 382 Pfam PF13378 Enolase C-terminal domain-like 129 355 3.7E-62 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS14630 674cf8b42ca13a3e48485a75fae78c63 86 Pfam PF00886 Ribosomal protein S16 8 68 3.8E-24 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14630 674cf8b42ca13a3e48485a75fae78c63 86 SUPERFAMILY SSF54565 1 76 6.41E-28 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14630 674cf8b42ca13a3e48485a75fae78c63 86 Gene3D G3DSA:3.30.1320.10 1 79 8.9E-31 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14630 674cf8b42ca13a3e48485a75fae78c63 86 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 77 4.6E-27 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14630 674cf8b42ca13a3e48485a75fae78c63 86 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.958 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS01715 a6abf58c8c7898c0b356fcf219126b27 402 Pfam PF07690 Major Facilitator Superfamily 28 354 2.2E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS01715 a6abf58c8c7898c0b356fcf219126b27 402 Gene3D G3DSA:1.20.1250.20 208 391 5.8E-18 T 29-03-2018 CVS48_RS01715 a6abf58c8c7898c0b356fcf219126b27 402 Gene3D G3DSA:1.20.1250.20 19 207 2.2E-18 T 29-03-2018 CVS48_RS01715 a6abf58c8c7898c0b356fcf219126b27 402 PRINTS PR01035 Tetracycline resistance protein signature 143 165 3.1E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CVS48_RS01715 a6abf58c8c7898c0b356fcf219126b27 402 PRINTS PR01035 Tetracycline resistance protein signature 257 277 3.1E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CVS48_RS01715 a6abf58c8c7898c0b356fcf219126b27 402 PRINTS PR01035 Tetracycline resistance protein signature 55 74 3.1E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CVS48_RS01715 a6abf58c8c7898c0b356fcf219126b27 402 PRINTS PR01035 Tetracycline resistance protein signature 345 368 3.1E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CVS48_RS01715 a6abf58c8c7898c0b356fcf219126b27 402 SUPERFAMILY SSF103473 21 388 4.19E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 Gene3D G3DSA:2.70.210.12 2 156 7.0E-54 T 29-03-2018 IPR006169 GTP1/OBG domain CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 Pfam PF01018 GTP1/OBG 4 158 9.4E-57 T 29-03-2018 IPR006169 GTP1/OBG domain CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 Pfam PF01926 50S ribosome-binding GTPase 161 289 2.5E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 SUPERFAMILY SSF52540 151 343 9.77E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 335 1.3E-136 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 5.1E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 5.1E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 5.1E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 5.1E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 PIRSF PIRSF002401 1 366 9.5E-132 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 Hamap MF_01454 GTPase Obg [obg]. 2 336 46.766 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 Gene3D G3DSA:3.40.50.300 159 347 2.2E-34 T 29-03-2018 CVS48_RS08075 7327439bfb297f21358d24b1914ab74d 378 SUPERFAMILY SSF82051 2 158 1.31E-54 T 29-03-2018 IPR006169 GTP1/OBG domain CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 154 750 3.6E-178 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 Gene3D G3DSA:1.20.1110.10 203 455 1.8E-50 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 ProSitePatterns PS01047 Heavy-metal-associated domain. 15 44 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 Pfam PF00122 E1-E2 ATPase 240 420 3.3E-60 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00943 Copper-transporting ATPase signature 362 376 5.4E-13 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00943 Copper-transporting ATPase signature 617 634 5.4E-13 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00943 Copper-transporting ATPase signature 209 228 5.4E-13 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00943 Copper-transporting ATPase signature 424 439 5.4E-13 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00943 Copper-transporting ATPase signature 157 176 5.4E-13 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 211 718 7.2E-92 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 SUPERFAMILY SSF81653 241 339 2.75E-31 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 441 455 4.8E-28 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 576 4.8E-28 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 587 597 4.8E-28 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 289 303 4.8E-28 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 640 659 4.8E-28 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 663 675 4.8E-28 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 Pfam PF00403 Heavy-metal-associated domain 13 73 2.0E-15 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 Gene3D G3DSA:3.40.1110.10 456 565 5.5E-31 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 443 449 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 172 749 1.6E-188 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 Gene3D G3DSA:3.40.50.1000 566 706 9.1E-46 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 Pfam PF00702 haloacid dehalogenase-like hydrolase 437 654 1.0E-45 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 SUPERFAMILY SSF81665 689 728 1.7E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 SUPERFAMILY SSF81665 340 435 1.7E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 SUPERFAMILY SSF81665 192 243 1.7E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 Gene3D G3DSA:3.30.70.100 7 83 2.7E-23 T 29-03-2018 CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 SUPERFAMILY SSF56784 439 459 7.22E-60 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 SUPERFAMILY SSF56784 498 747 7.22E-60 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS19765 80b6703bb39bc7a6ef6b38048c78367b 759 SUPERFAMILY SSF55008 5 79 2.36E-23 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 Gene3D G3DSA:1.10.490.10 1 159 4.4E-46 T 29-03-2018 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 Gene3D G3DSA:2.40.30.10 160 260 8.0E-28 T 29-03-2018 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 Gene3D G3DSA:3.40.50.80 261 403 1.9E-27 T 29-03-2018 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 Hamap MF_01252 Flavohemoprotein [hmp]. 1 404 55.588 T 29-03-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 SUPERFAMILY SSF63380 151 262 9.08E-29 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 Pfam PF00970 Oxidoreductase FAD-binding domain 158 261 2.7E-6 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 Pfam PF00175 Oxidoreductase NAD-binding domain 272 379 9.3E-16 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 SUPERFAMILY SSF52343 263 400 1.09E-36 T 29-03-2018 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 Pfam PF00042 Globin 7 103 1.6E-11 T 29-03-2018 IPR000971 Globin GO:0020037 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 PRINTS PR00406 Cytochrome B5 reductase signature 248 262 3.0E-5 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 PRINTS PR00406 Cytochrome B5 reductase signature 366 374 3.0E-5 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 PRINTS PR00406 Cytochrome B5 reductase signature 271 290 3.0E-5 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CVS48_RS15495 9f360ecd720cccdbe05faad4f9d83169 405 SUPERFAMILY SSF46458 1 144 1.08E-40 T 29-03-2018 IPR009050 Globin-like CVS48_RS19975 a447377e270ac08e114902c5dd715fc2 75 Gene3D G3DSA:3.10.290.10 1 73 2.1E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS19975 a447377e270ac08e114902c5dd715fc2 75 SUPERFAMILY SSF55174 6 72 5.15E-16 T 29-03-2018 CVS48_RS19975 a447377e270ac08e114902c5dd715fc2 75 Pfam PF13275 S4 domain 13 71 5.6E-21 T 29-03-2018 CVS48_RS17755 effd2b5c0b329021c088760f24901166 576 Pfam PF00920 Dehydratase family 41 557 2.1E-176 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS17755 effd2b5c0b329021c088760f24901166 576 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS17755 effd2b5c0b329021c088760f24901166 576 SUPERFAMILY SSF143975 4 376 4.18E-123 T 29-03-2018 CVS48_RS17755 effd2b5c0b329021c088760f24901166 576 SUPERFAMILY SSF52016 378 563 2.35E-56 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS07140 3eaa6ef4ffc44765e61f799586424efa 350 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 127 3.5E-28 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CVS48_RS07140 3eaa6ef4ffc44765e61f799586424efa 350 SUPERFAMILY SSF55347 139 281 5.89E-34 T 29-03-2018 CVS48_RS07140 3eaa6ef4ffc44765e61f799586424efa 350 SUPERFAMILY SSF51735 5 165 6.34E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07140 3eaa6ef4ffc44765e61f799586424efa 350 Gene3D G3DSA:3.30.360.10 149 349 1.9E-42 T 29-03-2018 CVS48_RS07140 3eaa6ef4ffc44765e61f799586424efa 350 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 142 256 4.1E-21 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CVS48_RS07140 3eaa6ef4ffc44765e61f799586424efa 350 Gene3D G3DSA:3.40.50.720 4 148 7.5E-40 T 29-03-2018 CVS48_RS26975 d77c4d2329d626e6cf6692632b046a2d 460 Pfam PF00772 DnaB-like helicase N terminal domain 15 116 1.1E-32 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CVS48_RS26975 d77c4d2329d626e6cf6692632b046a2d 460 Gene3D G3DSA:3.40.50.300 175 459 7.0E-67 T 29-03-2018 CVS48_RS26975 d77c4d2329d626e6cf6692632b046a2d 460 SUPERFAMILY SSF48024 13 124 1.44E-35 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CVS48_RS26975 d77c4d2329d626e6cf6692632b046a2d 460 Pfam PF03796 DnaB-like helicase C terminal domain 195 450 2.9E-113 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CVS48_RS26975 d77c4d2329d626e6cf6692632b046a2d 460 SUPERFAMILY SSF52540 193 444 2.18E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26975 d77c4d2329d626e6cf6692632b046a2d 460 Gene3D G3DSA:1.10.860.10 5 157 1.1E-45 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CVS48_RS26975 d77c4d2329d626e6cf6692632b046a2d 460 SMART SM00382 212 410 5.5E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS26975 d77c4d2329d626e6cf6692632b046a2d 460 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 15 451 3.9E-174 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CVS48_RS11560 e5b696dda792cb671898619a2db3d91c 176 SUPERFAMILY SSF48498 71 154 2.18E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS11560 e5b696dda792cb671898619a2db3d91c 176 Gene3D G3DSA:1.10.10.60 1 52 7.3E-15 T 29-03-2018 CVS48_RS11560 e5b696dda792cb671898619a2db3d91c 176 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 7.8E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS11560 e5b696dda792cb671898619a2db3d91c 176 SUPERFAMILY SSF46689 2 68 1.02E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS11560 e5b696dda792cb671898619a2db3d91c 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 3.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS11560 e5b696dda792cb671898619a2db3d91c 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 3.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS11560 e5b696dda792cb671898619a2db3d91c 176 Gene3D G3DSA:1.10.357.10 53 172 6.4E-15 T 29-03-2018 CVS48_RS05105 9f17290e9484c4a0a3886d041703a50e 368 SUPERFAMILY SSF53383 18 366 1.33E-76 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS05105 9f17290e9484c4a0a3886d041703a50e 368 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 16 366 54.587 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CVS48_RS05105 9f17290e9484c4a0a3886d041703a50e 368 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 19 365 1.6E-94 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CVS48_RS05105 9f17290e9484c4a0a3886d041703a50e 368 Gene3D G3DSA:3.90.1150.10 252 366 7.1E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS05105 9f17290e9484c4a0a3886d041703a50e 368 Pfam PF00155 Aminotransferase class I and II 35 360 6.1E-48 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS05105 9f17290e9484c4a0a3886d041703a50e 368 Gene3D G3DSA:3.40.640.10 48 251 1.6E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 Gene3D G3DSA:3.40.50.2300 802 941 1.0E-30 T 29-03-2018 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 SMART SM00387 575 693 2.2E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 SMART SM00388 463 528 1.6E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 SUPERFAMILY SSF55874 517 691 2.1E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 SUPERFAMILY SSF47384 447 529 1.45E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 Gene3D G3DSA:3.30.450.20 120 466 1.2E-6 T 29-03-2018 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 Gene3D G3DSA:1.10.287.130 467 524 3.5E-18 T 29-03-2018 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 SUPERFAMILY SSF52172 822 938 2.85E-32 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 575 689 1.2E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 Gene3D G3DSA:3.30.565.10 532 700 3.1E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 675 688 5.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 644 5.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 616 630 5.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 651 669 5.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 Pfam PF00072 Response regulator receiver domain 824 933 1.1E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 SMART SM00448 822 933 7.6E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12045 4a6534cf15e634e148c3e428608fac80 941 Pfam PF00512 His Kinase A (phospho-acceptor) domain 464 528 1.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS08205 ada84a11fbbe43181b1241db644d389a 133 SUPERFAMILY SSF158442 3 127 2.88E-26 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CVS48_RS08205 ada84a11fbbe43181b1241db644d389a 133 Pfam PF02600 Disulfide bond formation protein DsbB 5 126 5.9E-13 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CVS48_RS08205 ada84a11fbbe43181b1241db644d389a 133 Gene3D G3DSA:1.20.1550.10 1 102 2.8E-21 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CVS48_RS08205 ada84a11fbbe43181b1241db644d389a 133 PIRSF PIRSF036659 1 133 2.6E-44 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC CVS48_RS20710 a9eb94f947b99d43de6bd9d7462f6f69 522 Pfam PF07690 Major Facilitator Superfamily 24 407 2.9E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS20710 a9eb94f947b99d43de6bd9d7462f6f69 522 Gene3D G3DSA:1.20.1250.20 14 205 6.5E-26 T 29-03-2018 CVS48_RS20710 a9eb94f947b99d43de6bd9d7462f6f69 522 SUPERFAMILY SSF103473 482 512 9.55E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS20710 a9eb94f947b99d43de6bd9d7462f6f69 522 SUPERFAMILY SSF103473 253 423 9.55E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS20710 a9eb94f947b99d43de6bd9d7462f6f69 522 SUPERFAMILY SSF103473 9 202 9.55E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS20710 a9eb94f947b99d43de6bd9d7462f6f69 522 Gene3D G3DSA:1.20.1250.20 257 517 6.9E-15 T 29-03-2018 CVS48_RS27035 8f5ae64928d24fef25f19cc22c61ba58 322 Gene3D G3DSA:3.40.190.10 134 292 7.8E-10 T 29-03-2018 CVS48_RS27035 8f5ae64928d24fef25f19cc22c61ba58 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 6.1E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS27035 8f5ae64928d24fef25f19cc22c61ba58 322 SUPERFAMILY SSF53850 120 283 1.51E-12 T 29-03-2018 CVS48_RS27035 8f5ae64928d24fef25f19cc22c61ba58 322 PIRSF PIRSF017082 1 322 7.4E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS16425 12593ee0146c3f846a7002a0bf6ab356 240 Gene3D G3DSA:3.40.50.300 105 238 1.6E-4 T 29-03-2018 CVS48_RS16425 12593ee0146c3f846a7002a0bf6ab356 240 SUPERFAMILY SSF52540 68 110 4.75E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16425 12593ee0146c3f846a7002a0bf6ab356 240 Gene3D G3DSA:3.40.50.300 65 104 4.6E-9 T 29-03-2018 CVS48_RS16425 12593ee0146c3f846a7002a0bf6ab356 240 SUPERFAMILY SSF52540 91 186 1.05E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07120 5f800ffdc34a80160c2d152526ae8b1a 390 PIRSF PIRSF000390 1 390 2.5E-112 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CVS48_RS07120 5f800ffdc34a80160c2d152526ae8b1a 390 Gene3D G3DSA:3.40.640.10 2 250 5.0E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS07120 5f800ffdc34a80160c2d152526ae8b1a 390 Gene3D G3DSA:3.90.1150.10 251 390 3.1E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS07120 5f800ffdc34a80160c2d152526ae8b1a 390 SUPERFAMILY SSF53383 4 389 9.52E-114 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS07120 5f800ffdc34a80160c2d152526ae8b1a 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 12 385 3.7E-138 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 Gene3D G3DSA:3.40.640.10 138 378 6.2E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 SMART SM00345 24 83 7.4E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 Gene3D G3DSA:1.10.10.10 12 85 2.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 8.5E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 8.5E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 SUPERFAMILY SSF46785 15 85 5.24E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 Gene3D G3DSA:3.90.1150.10 379 471 1.9E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 Pfam PF00155 Aminotransferase class I and II 147 437 1.4E-24 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 83 3.9E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18925 832a878ff2bf8c239ff5d5ff71727ba9 474 SUPERFAMILY SSF53383 95 472 1.02E-82 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS18830 e23db405ca992036d43c441da99ea3bc 435 Pfam PF07804 HipA-like C-terminal domain 177 405 3.6E-43 T 29-03-2018 IPR012893 HipA-like, C-terminal CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 SUPERFAMILY SSF69349 446 642 4.71E-31 T 29-03-2018 CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 SUPERFAMILY SSF69255 368 455 3.4E-33 T 29-03-2018 CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 Gene3D G3DSA:2.40.50.230 373 455 3.3E-35 T 29-03-2018 IPR006531 Gp5 N-terminal CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 25 507 5.6E-145 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 12 525 9.4E-186 T 29-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 Gene3D G3DSA:3.55.50.10 102 192 2.1E-33 T 29-03-2018 CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 Pfam PF05954 Phage late control gene D protein (GPD) 31 332 1.9E-103 T 29-03-2018 CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 598 707 4.3E-8 T 29-03-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 SUPERFAMILY SSF69279 192 366 7.82E-42 T 29-03-2018 CVS48_RS06645 8e9a5b0d140a986faca4711f918e1e6e 795 SUPERFAMILY SSF69279 14 188 1.45E-59 T 29-03-2018 CVS48_RS08155 004e750be891b18f19e9a11f618ff6d4 141 Pfam PF00436 Single-strand binding protein family 7 102 8.5E-7 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CVS48_RS08155 004e750be891b18f19e9a11f618ff6d4 141 Gene3D G3DSA:2.40.50.140 3 118 2.5E-13 T 29-03-2018 CVS48_RS08155 004e750be891b18f19e9a11f618ff6d4 141 SUPERFAMILY SSF50249 8 126 2.01E-8 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS02320 9a76c1d35a977baa7de9f29c1829dc69 265 Gene3D G3DSA:3.40.190.10 124 265 1.4E-54 T 29-03-2018 CVS48_RS02320 9a76c1d35a977baa7de9f29c1829dc69 265 Pfam PF03180 NLPA lipoprotein 30 265 1.7E-97 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS02320 9a76c1d35a977baa7de9f29c1829dc69 265 SUPERFAMILY SSF53850 30 265 2.05E-90 T 29-03-2018 CVS48_RS02320 9a76c1d35a977baa7de9f29c1829dc69 265 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 27 265 1.3E-75 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS02320 9a76c1d35a977baa7de9f29c1829dc69 265 Gene3D G3DSA:3.40.190.10 29 123 4.2E-23 T 29-03-2018 CVS48_RS02320 9a76c1d35a977baa7de9f29c1829dc69 265 PIRSF PIRSF002854 1 265 2.2E-106 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 SUPERFAMILY SSF52518 396 598 1.15E-50 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 Pfam PF02779 Transketolase, pyrimidine binding domain 399 572 1.4E-33 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 Pfam PF02780 Transketolase, C-terminal domain 589 710 1.4E-20 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 SMART SM00861 399 574 1.2E-39 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 Pfam PF00676 Dehydrogenase E1 component 41 346 2.7E-50 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 SUPERFAMILY SSF52922 583 717 2.0E-23 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 Gene3D G3DSA:3.40.50.920 590 719 3.3E-22 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 Gene3D G3DSA:3.40.50.970 395 589 6.7E-49 T 29-03-2018 CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 SUPERFAMILY SSF52518 23 369 8.13E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS08905 d3055fc7fa1f7e9a6f433eb510c0a65b 735 Gene3D G3DSA:3.40.50.970 24 350 8.3E-58 T 29-03-2018 CVS48_RS01165 1835d9039d9b14601bdd67355dad82a9 173 Pfam PF02830 V4R domain 109 171 1.1E-15 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR CVS48_RS01165 1835d9039d9b14601bdd67355dad82a9 173 SMART SM00989 104 171 7.1E-12 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR CVS48_RS01165 1835d9039d9b14601bdd67355dad82a9 173 SUPERFAMILY SSF111126 13 170 6.28E-25 T 29-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain CVS48_RS01165 1835d9039d9b14601bdd67355dad82a9 173 Gene3D G3DSA:3.30.1380.20 5 173 7.5E-33 T 29-03-2018 CVS48_RS08805 cb72b137455fbe3f85aa8cb728e77c6f 324 SUPERFAMILY SSF51735 1 320 2.38E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS08805 cb72b137455fbe3f85aa8cb728e77c6f 324 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 207 3.1E-23 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS08805 cb72b137455fbe3f85aa8cb728e77c6f 324 Gene3D G3DSA:3.40.50.720 1 185 9.6E-30 T 29-03-2018 CVS48_RS08805 cb72b137455fbe3f85aa8cb728e77c6f 324 Gene3D G3DSA:3.90.25.10 186 290 1.7E-42 T 29-03-2018 CVS48_RS27000 6984a32a08f0d403b430e674ead83279 124 Pfam PF01250 Ribosomal protein S6 3 91 1.7E-27 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27000 6984a32a08f0d403b430e674ead83279 124 Gene3D G3DSA:3.30.70.60 1 100 1.7E-31 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CVS48_RS27000 6984a32a08f0d403b430e674ead83279 124 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.9E-33 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27000 6984a32a08f0d403b430e674ead83279 124 SUPERFAMILY SSF54995 1 103 6.15E-37 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27000 6984a32a08f0d403b430e674ead83279 124 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.908 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CVS48_RS23390 48a2218a0d8357110335211de37db824 250 SUPERFAMILY SSF46785 3 76 2.3E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23390 48a2218a0d8357110335211de37db824 250 SMART SM00895 82 206 1.1E-18 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS23390 48a2218a0d8357110335211de37db824 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.2E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS23390 48a2218a0d8357110335211de37db824 250 SUPERFAMILY SSF48008 78 213 5.49E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS23390 48a2218a0d8357110335211de37db824 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 4.4E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS23390 48a2218a0d8357110335211de37db824 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 4.4E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS23390 48a2218a0d8357110335211de37db824 250 SMART SM00345 14 72 1.5E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS23390 48a2218a0d8357110335211de37db824 250 Gene3D G3DSA:1.20.120.530 75 223 1.2E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS23390 48a2218a0d8357110335211de37db824 250 Pfam PF07729 FCD domain 82 205 1.8E-27 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS23390 48a2218a0d8357110335211de37db824 250 Gene3D G3DSA:1.10.10.10 2 74 9.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 Gene3D G3DSA:3.40.50.300 177 362 5.9E-22 T 29-03-2018 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 SUPERFAMILY SSF81923 12 125 1.14E-15 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 SMART SM01086 777 869 9.1E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 SUPERFAMILY SSF52540 180 507 1.95E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 Gene3D G3DSA:1.10.1780.10 3 158 8.7E-20 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 314 326 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 777 851 1.7E-14 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 Pfam PF07724 AAA domain (Cdc48 subfamily) 604 770 1.8E-37 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 SMART SM00382 605 761 1.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 SMART SM00382 218 363 7.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 1.6E-32 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 672 1.6E-32 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 730 1.6E-32 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 609 627 1.6E-32 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 Gene3D G3DSA:3.40.50.300 560 791 6.1E-36 T 29-03-2018 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 Gene3D G3DSA:1.10.8.60 364 555 4.2E-36 T 29-03-2018 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 861 0.0 T 29-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 SUPERFAMILY SSF52540 554 850 4.22E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 223 356 1.4E-9 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS06695 fddb4ff1c52ec05c828fddb570aebb36 872 Gene3D G3DSA:1.10.8.60 792 872 2.6E-13 T 29-03-2018 CVS48_RS22205 347604fdb513e3e11ec5651e1a5e75fd 877 SUPERFAMILY SSF56935 121 274 6.87E-47 T 29-03-2018 CVS48_RS22205 347604fdb513e3e11ec5651e1a5e75fd 877 SUPERFAMILY SSF56935 301 600 6.87E-47 T 29-03-2018 CVS48_RS22205 347604fdb513e3e11ec5651e1a5e75fd 877 SUPERFAMILY SSF56935 630 877 6.87E-47 T 29-03-2018 CVS48_RS22205 347604fdb513e3e11ec5651e1a5e75fd 877 SMART SM00965 61 112 3.4E-10 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS22205 347604fdb513e3e11ec5651e1a5e75fd 877 Pfam PF07715 TonB-dependent Receptor Plug Domain 136 253 4.9E-7 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS22205 347604fdb513e3e11ec5651e1a5e75fd 877 Gene3D G3DSA:2.170.130.10 132 269 9.6E-10 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS22205 347604fdb513e3e11ec5651e1a5e75fd 877 Gene3D G3DSA:2.40.170.20 303 877 6.3E-31 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 SMART SM00073 7 105 3.3E-29 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 SMART SM00260 559 699 1.0E-41 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 SUPERFAMILY SSF55874 385 565 4.06E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 SMART SM00387 427 567 8.6E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Gene3D G3DSA:2.40.50.180 590 645 1.1E-8 T 29-03-2018 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Gene3D G3DSA:1.20.120.160 4 150 2.0E-31 T 29-03-2018 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 430 566 4.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 SUPERFAMILY SSF47226 7 129 5.3E-31 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Pfam PF09078 CheY binding 186 248 1.0E-24 T 29-03-2018 IPR015162 CheY binding CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 SUPERFAMILY SSF47384 320 383 2.31E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 545 6.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 521 6.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 486 6.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 564 6.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Gene3D G3DSA:2.30.30.40 646 699 2.5E-20 T 29-03-2018 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Pfam PF01584 CheW-like domain 572 700 1.5E-27 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 SUPERFAMILY SSF55052 185 250 6.8E-20 T 29-03-2018 IPR015162 CheY binding CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Gene3D G3DSA:3.30.565.10 385 573 3.8E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 320 382 2.3E-16 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Gene3D G3DSA:1.10.287.560 319 383 3.4E-19 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 SMART SM01231 319 382 5.8E-21 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 SUPERFAMILY SSF50341 566 698 1.22E-31 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Pfam PF01627 Hpt domain 10 110 5.5E-18 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS16790 ffda9a68a92ed810381673295a2fc088 714 Gene3D G3DSA:3.30.70.400 184 249 2.3E-24 T 29-03-2018 IPR015162 CheY binding CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SUPERFAMILY SSF50891 632 757 4.93E-32 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SUPERFAMILY SSF50891 923 1055 2.01E-25 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 TIGRFAM TIGR02712 urea_carbox: urea carboxylase 2 1204 0.0 T 29-03-2018 IPR014084 Urea carboxylase KEGG: 00220+3.5.1.54+6.3.4.6|KEGG: 00791+3.5.1.54+6.3.4.6|MetaCyc: PWY-5169|MetaCyc: PWY-5703 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 107 8.1E-42 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1161 1178 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SUPERFAMILY SSF56059 83 352 9.9E-68 T 29-03-2018 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SMART SM00796 806 1039 4.1E-105 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SUPERFAMILY SSF52440 2 111 1.73E-44 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 807 1029 7.8E-44 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 472 751 6.6E-90 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Pfam PF00364 Biotin-requiring enzyme 1145 1204 6.4E-15 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SUPERFAMILY SSF160467 808 900 7.72E-17 T 29-03-2018 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 448 773 7.1E-96 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SMART SM00878 336 440 1.0E-57 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Gene3D G3DSA:2.40.100.10 894 1057 1.9E-45 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SMART SM00797 471 768 4.0E-171 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Gene3D G3DSA:2.40.50.100 1116 1210 1.1E-19 T 29-03-2018 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Pfam PF02785 Biotin carboxylase C-terminal domain 336 440 4.6E-36 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 4.4E-61 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Gene3D G3DSA:3.30.1490.20 124 208 9.2E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SUPERFAMILY SSF51230 1130 1204 6.67E-20 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Gene3D G3DSA:3.30.470.20 209 443 1.6E-95 T 29-03-2018 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Gene3D G3DSA:3.30.1360.40 790 888 1.8E-25 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 Gene3D G3DSA:3.40.50.20 1 123 1.1E-48 T 29-03-2018 CVS48_RS12665 4244c59e530072fd6cd574dca1c2c610 1214 SUPERFAMILY SSF51246 330 442 1.73E-36 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CVS48_RS10205 def3d0d2fba472540f8778d9303b3494 461 Gene3D G3DSA:3.40.50.880 180 440 4.6E-13 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS10205 def3d0d2fba472540f8778d9303b3494 461 Pfam PF09822 ABC-type uncharacterized transport system 40 276 2.1E-23 T 29-03-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 Hamap MF_00163 Peptide deformylase [def]. 1 166 26.979 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 Pfam PF01327 Polypeptide deformylase 3 158 5.1E-49 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 PIRSF PIRSF004749 1 167 1.6E-49 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 SUPERFAMILY SSF56420 1 165 8.9E-60 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 Gene3D G3DSA:3.90.45.10 1 167 6.7E-55 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 159 1.1E-35 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 PRINTS PR01576 Peptide deformylase signature 109 127 4.2E-30 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 PRINTS PR01576 Peptide deformylase signature 97 108 4.2E-30 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 PRINTS PR01576 Peptide deformylase signature 33 62 4.2E-30 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS01980 a57e72aa6d59e00bc4c5866fcf5e9737 177 PRINTS PR01576 Peptide deformylase signature 128 157 4.2E-30 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 Pfam PF08534 Redoxin 6 160 2.8E-34 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 Pfam PF00462 Glutaredoxin 173 231 1.1E-13 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 Gene3D G3DSA:3.40.30.10 3 163 2.0E-31 T 29-03-2018 CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 Gene3D G3DSA:3.40.30.10 172 242 6.5E-18 T 29-03-2018 CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 164 242 7.4E-37 T 29-03-2018 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 SUPERFAMILY SSF52833 5 239 8.94E-45 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 ProSitePatterns PS00195 Glutaredoxin active site. 175 191 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 PRINTS PR00160 Glutaredoxin signature 214 227 1.7E-11 T 29-03-2018 IPR014025 Glutaredoxin subgroup CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 PRINTS PR00160 Glutaredoxin signature 228 241 1.7E-11 T 29-03-2018 IPR014025 Glutaredoxin subgroup CVS48_RS19755 c6575a14540dcaddca719f784f24b9c5 242 PRINTS PR00160 Glutaredoxin signature 173 191 1.7E-11 T 29-03-2018 IPR014025 Glutaredoxin subgroup CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.9E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 Gene3D G3DSA:3.40.190.10 88 178 6.2E-14 T 29-03-2018 CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 Gene3D G3DSA:1.10.10.10 1 83 1.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 SUPERFAMILY SSF46785 1 85 5.99E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 Gene3D G3DSA:3.40.190.10 179 261 1.5E-9 T 29-03-2018 CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 Pfam PF03466 LysR substrate binding domain 88 290 1.9E-26 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS22140 95d5773e6cdf8661c909f9727bc1fb7c 312 SUPERFAMILY SSF53850 86 297 7.76E-29 T 29-03-2018 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 11 592 1.8E-279 T 29-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 Gene3D G3DSA:1.20.58.100 449 559 3.7E-34 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 SUPERFAMILY SSF46977 456 592 1.44E-44 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 Gene3D G3DSA:4.10.80.40 560 592 7.2E-18 T 29-03-2018 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 Gene3D G3DSA:3.50.50.60 294 432 4.0E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 Gene3D G3DSA:3.50.50.60 6 293 6.2E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 SUPERFAMILY SSF51905 9 264 6.7E-79 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 SUPERFAMILY SSF51905 363 428 6.7E-79 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 Pfam PF00890 FAD binding domain 14 408 6.0E-118 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 SUPERFAMILY SSF56425 241 359 8.97E-43 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 591 4.6E-39 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 1.1E-5 T 29-03-2018 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 386 393 1.1E-5 T 29-03-2018 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 PIRSF PIRSF000171 4 581 3.8E-39 T 29-03-2018 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 48 57 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27900 94d8b9c4d01497c91680235e8b7a466f 592 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 14 591 6.1E-240 T 29-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS08740 69b2a8ac1c5a5c7a4349d91efcad1973 237 SUPERFAMILY SSF52540 3 235 2.08E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08740 69b2a8ac1c5a5c7a4349d91efcad1973 237 SMART SM00382 28 229 1.2E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08740 69b2a8ac1c5a5c7a4349d91efcad1973 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS08740 69b2a8ac1c5a5c7a4349d91efcad1973 237 Pfam PF00005 ABC transporter 19 165 1.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS08740 69b2a8ac1c5a5c7a4349d91efcad1973 237 Gene3D G3DSA:3.40.50.300 1 235 1.1E-55 T 29-03-2018 CVS48_RS21280 039137e0c13c0a9357f4e70d53bd9cdb 327 SUPERFAMILY SSF53850 92 287 7.6E-10 T 29-03-2018 CVS48_RS21280 039137e0c13c0a9357f4e70d53bd9cdb 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 1.4E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21280 039137e0c13c0a9357f4e70d53bd9cdb 327 Gene3D G3DSA:3.40.50.1980 5 127 0.0015 T 29-03-2018 CVS48_RS21280 039137e0c13c0a9357f4e70d53bd9cdb 327 Gene3D G3DSA:3.40.190.10 128 237 7.3E-6 T 29-03-2018 CVS48_RS21280 039137e0c13c0a9357f4e70d53bd9cdb 327 PIRSF PIRSF017082 1 326 2.1E-79 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS02970 b102252b735d7ea210b8cd0d6522d416 416 PIRSF PIRSF000412 1 416 8.8E-165 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CVS48_RS02970 b102252b735d7ea210b8cd0d6522d416 416 Pfam PF00464 Serine hydroxymethyltransferase 8 382 1.1E-169 T 29-03-2018 CVS48_RS02970 b102252b735d7ea210b8cd0d6522d416 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CVS48_RS02970 b102252b735d7ea210b8cd0d6522d416 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 414 51.957 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CVS48_RS02970 b102252b735d7ea210b8cd0d6522d416 416 SUPERFAMILY SSF53383 8 414 4.13E-178 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS02970 b102252b735d7ea210b8cd0d6522d416 416 Gene3D G3DSA:3.40.640.10 37 272 3.0E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS02970 b102252b735d7ea210b8cd0d6522d416 416 Gene3D G3DSA:3.90.1150.10 273 412 5.9E-61 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS10665 f01e230d79a09a747a53707b8416e246 147 SUPERFAMILY SSF82784 1 139 1.7E-38 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS10665 f01e230d79a09a747a53707b8416e246 147 Pfam PF02566 OsmC-like protein 35 129 1.2E-17 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS10665 f01e230d79a09a747a53707b8416e246 147 Gene3D G3DSA:3.30.300.20 25 141 2.8E-28 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS10665 f01e230d79a09a747a53707b8416e246 147 Gene3D G3DSA:2.20.25.10 1 24 5.0E-11 T 29-03-2018 CVS48_RS09415 449314e3b904451f1a38c513f81c0fd0 232 SUPERFAMILY SSF56529 21 231 6.28E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS09415 449314e3b904451f1a38c513f81c0fd0 232 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 27 230 1.3E-50 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS09415 449314e3b904451f1a38c513f81c0fd0 232 Gene3D G3DSA:3.90.850.10 8 232 1.4E-73 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS24185 156a56031647a3358790feebeda5aa86 124 SUPERFAMILY SSF54427 1 123 5.85E-39 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS24185 156a56031647a3358790feebeda5aa86 124 Gene3D G3DSA:3.10.450.50 2 124 2.4E-22 T 29-03-2018 CVS48_RS24185 156a56031647a3358790feebeda5aa86 124 Pfam PF11533 Protein of unknown function (DUF3225) 1 123 3.5E-62 T 29-03-2018 IPR024507 Protein of unknown function DUF3225 CVS48_RS26230 8000a9b3582a9154a92a122cbc11aa6e 247 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 19 203 3.1E-32 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CVS48_RS26230 8000a9b3582a9154a92a122cbc11aa6e 247 SUPERFAMILY SSF50486 14 218 7.85E-51 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CVS48_RS26230 8000a9b3582a9154a92a122cbc11aa6e 247 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 17 211 23.035 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CVS48_RS26230 8000a9b3582a9154a92a122cbc11aa6e 247 Gene3D G3DSA:3.10.300.10 12 216 6.1E-39 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 SUPERFAMILY SSF52374 1 198 4.22E-132 T 29-03-2018 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 SUPERFAMILY SSF52374 410 670 4.22E-132 T 29-03-2018 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 Gene3D G3DSA:3.40.50.620 46 203 8.7E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 SUPERFAMILY SSF47323 673 943 1.74E-68 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 Gene3D G3DSA:3.90.740.10 204 398 1.3E-54 T 29-03-2018 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 Pfam PF08264 Anticodon-binding domain of tRNA 706 867 2.9E-25 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 Gene3D G3DSA:3.40.50.620 399 616 1.2E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 944 20.64 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 Pfam PF06827 Zinc finger found in FPG and IleRS 914 941 6.1E-6 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 Gene3D G3DSA:1.10.730.10 617 842 1.1E-53 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 408 423 5.3E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 539 552 5.3E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 5.3E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 582 591 5.3E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 233 256 5.3E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 661 7.1E-190 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 Gene3D G3DSA:3.30.2320.20 843 917 6.2E-22 T 29-03-2018 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 SUPERFAMILY SSF50677 200 410 6.59E-49 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CVS48_RS22250 3b306f509fc16dc0c3456ffdc48836c3 953 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 869 2.3E-260 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CVS48_RS03245 3b025ac4d6b42f6de0d44c300e48bcea 287 Gene3D G3DSA:3.40.50.720 118 285 3.4E-27 T 29-03-2018 CVS48_RS03245 3b025ac4d6b42f6de0d44c300e48bcea 287 Gene3D G3DSA:3.40.50.10860 3 117 4.7E-34 T 29-03-2018 CVS48_RS03245 3b025ac4d6b42f6de0d44c300e48bcea 287 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 95 2.8E-20 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CVS48_RS03245 3b025ac4d6b42f6de0d44c300e48bcea 287 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 10 283 4.1E-69 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CVS48_RS03245 3b025ac4d6b42f6de0d44c300e48bcea 287 SUPERFAMILY SSF53223 8 107 2.82E-28 T 29-03-2018 CVS48_RS03245 3b025ac4d6b42f6de0d44c300e48bcea 287 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 282 30.312 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CVS48_RS03245 3b025ac4d6b42f6de0d44c300e48bcea 287 SUPERFAMILY SSF51735 108 283 6.9E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS03245 3b025ac4d6b42f6de0d44c300e48bcea 287 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 122 172 2.3E-9 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CVS48_RS23050 1880dfff03b533fa6fc9d72a41ad97ae 324 Gene3D G3DSA:1.10.10.60 228 271 8.6E-12 T 29-03-2018 CVS48_RS23050 1880dfff03b533fa6fc9d72a41ad97ae 324 Gene3D G3DSA:1.10.10.60 272 324 1.7E-10 T 29-03-2018 CVS48_RS23050 1880dfff03b533fa6fc9d72a41ad97ae 324 Gene3D G3DSA:3.40.50.880 6 227 7.2E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS23050 1880dfff03b533fa6fc9d72a41ad97ae 324 SUPERFAMILY SSF52317 5 203 6.72E-31 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS23050 1880dfff03b533fa6fc9d72a41ad97ae 324 Pfam PF01965 DJ-1/PfpI family 44 182 2.9E-9 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS23050 1880dfff03b533fa6fc9d72a41ad97ae 324 SUPERFAMILY SSF46689 220 271 8.96E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS23050 1880dfff03b533fa6fc9d72a41ad97ae 324 SMART SM00342 237 320 5.6E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS23050 1880dfff03b533fa6fc9d72a41ad97ae 324 SUPERFAMILY SSF46689 273 323 1.75E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS23050 1880dfff03b533fa6fc9d72a41ad97ae 324 Pfam PF12833 Helix-turn-helix domain 243 322 2.0E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 SUPERFAMILY SSF46785 1 85 2.95E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.1E-26 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 Gene3D G3DSA:3.40.190.10 177 267 5.3E-27 T 29-03-2018 CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 SUPERFAMILY SSF53850 90 285 3.46E-35 T 29-03-2018 CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 Gene3D G3DSA:1.10.10.10 1 90 4.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 Gene3D G3DSA:3.40.190.10 91 176 4.4E-20 T 29-03-2018 CVS48_RS17780 303cd770121f069e0af7167bc944b83d 299 Pfam PF03466 LysR substrate binding domain 88 284 1.3E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS06595 63218b5ac6350a158e33304401999c5d 291 SUPERFAMILY SSF103481 40 133 5.75E-12 T 29-03-2018 CVS48_RS06595 63218b5ac6350a158e33304401999c5d 291 Pfam PF00892 EamA-like transporter family 141 277 4.4E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS06595 63218b5ac6350a158e33304401999c5d 291 Pfam PF00892 EamA-like transporter family 3 129 1.9E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS06595 63218b5ac6350a158e33304401999c5d 291 SUPERFAMILY SSF103481 181 282 3.14E-13 T 29-03-2018 CVS48_RS09375 18cff6fa4084f099dd89cd14d83e254c 246 SMART SM00382 30 218 4.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS09375 18cff6fa4084f099dd89cd14d83e254c 246 Pfam PF00005 ABC transporter 21 169 2.6E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS09375 18cff6fa4084f099dd89cd14d83e254c 246 SUPERFAMILY SSF52540 5 240 1.1E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09375 18cff6fa4084f099dd89cd14d83e254c 246 PIRSF PIRSF039085 2 246 1.6E-108 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS09375 18cff6fa4084f099dd89cd14d83e254c 246 Gene3D G3DSA:3.40.50.300 1 245 6.3E-77 T 29-03-2018 CVS48_RS09375 18cff6fa4084f099dd89cd14d83e254c 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 SUPERFAMILY SSF52821 323 449 3.54E-28 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 SUPERFAMILY SSF52821 474 570 9.04E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 SMART SM00450 485 582 0.52 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 SMART SM00450 347 446 0.01 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 SMART SM00450 224 322 2.1E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 SMART SM00450 596 690 2.7E-7 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 Gene3D G3DSA:3.40.250.10 333 466 4.0E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 Gene3D G3DSA:3.40.250.10 583 698 2.5E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 Gene3D G3DSA:3.40.250.10 217 330 7.1E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 SUPERFAMILY SSF51182 36 219 3.49E-30 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 Gene3D G3DSA:3.40.250.10 467 572 1.4E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 Gene3D G3DSA:2.60.120.10 26 213 1.1E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 SUPERFAMILY SSF52821 223 338 1.83E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 Pfam PF00581 Rhodanese-like domain 601 687 6.6E-6 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 Pfam PF00581 Rhodanese-like domain 349 441 5.3E-6 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 Pfam PF00581 Rhodanese-like domain 228 318 5.3E-9 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS17925 7d45ef67589620fb9728fbbbc77509f7 751 SUPERFAMILY SSF52821 594 736 1.26E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS04540 2f16bdafea4c3922b31abd1a92772b09 349 PIRSF PIRSF001439 36 324 4.0E-49 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CVS48_RS04540 2f16bdafea4c3922b31abd1a92772b09 349 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 11 312 3.1E-97 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CVS48_RS04540 2f16bdafea4c3922b31abd1a92772b09 349 SUPERFAMILY SSF51735 2 337 2.05E-92 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS04540 2f16bdafea4c3922b31abd1a92772b09 349 Gene3D G3DSA:3.40.50.720 139 296 1.6E-25 T 29-03-2018 CVS48_RS04540 2f16bdafea4c3922b31abd1a92772b09 349 Gene3D G3DSA:3.30.1780.10 1 138 1.3E-32 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CVS48_RS28340 ba43cd8c8e8d9410c6fc3dcc81eefb96 198 Pfam PF02620 Uncharacterized ACR, COG1399 65 195 3.7E-16 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 4 401 1.4E-217 T 29-03-2018 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 SUPERFAMILY SSF53901 277 400 2.77E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 SUPERFAMILY SSF53901 5 276 4.76E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 Pfam PF00108 Thiolase, N-terminal domain 6 268 2.8E-77 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 399 2.9E-136 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 Gene3D G3DSA:3.40.47.10 2 147 4.8E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 Gene3D G3DSA:3.40.47.10 160 275 5.2E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 PIRSF PIRSF000429 1 401 1.7E-132 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 Gene3D G3DSA:3.40.47.10 276 398 3.1E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS22430 719c5315688958d4126ed5abcf2c651b 401 Pfam PF02803 Thiolase, C-terminal domain 277 400 7.1E-45 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS19450 9b16fb973c23ca5440c928ba47e7ceea 258 Gene3D G3DSA:3.40.50.300 1 256 2.3E-69 T 29-03-2018 CVS48_RS19450 9b16fb973c23ca5440c928ba47e7ceea 258 Pfam PF00005 ABC transporter 25 168 2.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19450 9b16fb973c23ca5440c928ba47e7ceea 258 SUPERFAMILY SSF52540 4 243 5.97E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19450 9b16fb973c23ca5440c928ba47e7ceea 258 SMART SM00382 33 218 1.1E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19450 9b16fb973c23ca5440c928ba47e7ceea 258 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 436 455 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 334 1.8E-30 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 SUPERFAMILY SSF52467 158 365 2.86E-39 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 Gene3D G3DSA:3.40.50.1220 193 358 3.1E-40 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 400 548 8.0E-34 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 SUPERFAMILY SSF52518 375 556 1.61E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 Gene3D G3DSA:3.40.50.970 359 564 1.1E-42 T 29-03-2018 CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 Gene3D G3DSA:3.40.50.970 1 192 2.1E-43 T 29-03-2018 CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 170 6.3E-44 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS20175 c263854446fccd53de43926a8a49e8f7 575 SUPERFAMILY SSF52518 4 177 6.34E-45 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS00320 0d4f240ae80d199b3ee284808f046b7c 230 SMART SM00862 152 228 8.5E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS00320 0d4f240ae80d199b3ee284808f046b7c 230 Gene3D G3DSA:1.10.10.10 126 230 8.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00320 0d4f240ae80d199b3ee284808f046b7c 230 Gene3D G3DSA:3.40.50.2300 3 125 3.0E-32 T 29-03-2018 CVS48_RS00320 0d4f240ae80d199b3ee284808f046b7c 230 SUPERFAMILY SSF52172 8 186 4.68E-37 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS00320 0d4f240ae80d199b3ee284808f046b7c 230 SMART SM00448 6 116 5.8E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS00320 0d4f240ae80d199b3ee284808f046b7c 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 1.0E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS00320 0d4f240ae80d199b3ee284808f046b7c 230 Pfam PF00072 Response regulator receiver domain 8 116 5.6E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS09865 07c09fdf8ccaa5f197a1ea9d9c0abdd6 313 Gene3D G3DSA:3.40.50.1820 1 313 2.9E-64 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS09865 07c09fdf8ccaa5f197a1ea9d9c0abdd6 313 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 7 310 2.6E-127 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CVS48_RS09865 07c09fdf8ccaa5f197a1ea9d9c0abdd6 313 PIRSF PIRSF006431 1 313 1.5E-136 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CVS48_RS09865 07c09fdf8ccaa5f197a1ea9d9c0abdd6 313 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 35 43 5.6E-14 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CVS48_RS09865 07c09fdf8ccaa5f197a1ea9d9c0abdd6 313 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 61 72 5.6E-14 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CVS48_RS09865 07c09fdf8ccaa5f197a1ea9d9c0abdd6 313 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 105 119 5.6E-14 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CVS48_RS09865 07c09fdf8ccaa5f197a1ea9d9c0abdd6 313 Pfam PF00561 alpha/beta hydrolase fold 36 293 1.3E-27 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS09865 07c09fdf8ccaa5f197a1ea9d9c0abdd6 313 SUPERFAMILY SSF53474 2 304 9.92E-65 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS14395 95153d51b9c0545586db332434ff843d 327 SUPERFAMILY SSF103481 219 310 4.05E-11 T 29-03-2018 CVS48_RS14395 95153d51b9c0545586db332434ff843d 327 SUPERFAMILY SSF103481 53 161 3.01E-15 T 29-03-2018 CVS48_RS14395 95153d51b9c0545586db332434ff843d 327 Pfam PF00892 EamA-like transporter family 19 158 6.4E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS14395 95153d51b9c0545586db332434ff843d 327 Pfam PF00892 EamA-like transporter family 172 306 4.4E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Gene3D G3DSA:1.10.150.20 538 603 5.5E-32 T 29-03-2018 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Gene3D G3DSA:3.30.470.30 131 283 7.4E-51 T 29-03-2018 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SMART SM00292 623 700 1.5E-9 T 29-03-2018 IPR001357 BRCT domain CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Gene3D G3DSA:1.10.287.610 7 73 7.9E-26 T 29-03-2018 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SUPERFAMILY SSF56091 10 347 4.64E-111 T 29-03-2018 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Pfam PF12826 Helix-hairpin-helix motif 542 605 1.8E-25 T 29-03-2018 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 13 350 9.0E-117 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Gene3D G3DSA:3.40.50.10190 604 698 1.4E-26 T 29-03-2018 IPR001357 BRCT domain CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 127 156 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Pfam PF14520 Helix-hairpin-helix domain 478 532 4.2E-6 T 29-03-2018 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Gene3D G3DSA:1.10.150.20 464 537 2.3E-23 T 29-03-2018 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 PIRSF PIRSF001604 4 700 6.7E-241 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SUPERFAMILY SSF47781 435 615 1.63E-62 T 29-03-2018 IPR010994 RuvA domain 2-like CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Gene3D G3DSA:2.40.50.140 349 421 1.7E-35 T 29-03-2018 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SMART SM00278 544 563 300.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SMART SM00278 512 531 42.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SMART SM00278 576 595 32.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SMART SM00278 478 497 23.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 353 430 4.3E-36 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Hamap MF_01588 DNA ligase [ligA]. 8 697 53.54 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 17 693 5.9E-247 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 440 466 5.1E-10 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SMART SM00532 9 480 1.7E-256 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SUPERFAMILY SSF52113 623 698 7.66E-18 T 29-03-2018 IPR001357 BRCT domain CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 363 378 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 SUPERFAMILY SSF50249 349 432 2.23E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS28555 ef09f89bf2f84ea04521495daa53fb30 700 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 623 697 1.2E-12 T 29-03-2018 IPR001357 BRCT domain CVS48_RS05970 e98ab45a1cfe92615bf8f1e397e0e839 301 SUPERFAMILY SSF103481 43 139 5.1E-13 T 29-03-2018 CVS48_RS05970 e98ab45a1cfe92615bf8f1e397e0e839 301 Pfam PF00892 EamA-like transporter family 11 135 2.8E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS05970 e98ab45a1cfe92615bf8f1e397e0e839 301 Pfam PF00892 EamA-like transporter family 150 290 3.3E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS05970 e98ab45a1cfe92615bf8f1e397e0e839 301 SUPERFAMILY SSF103481 196 296 6.8E-9 T 29-03-2018 CVS48_RS16105 d2d4ff2a002c5eea46d2ec7f477b78d0 346 Pfam PF04773 FecR protein 137 229 5.0E-22 T 29-03-2018 IPR006860 FecR protein CVS48_RS16105 d2d4ff2a002c5eea46d2ec7f477b78d0 346 PIRSF PIRSF018266 14 346 1.0E-77 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS16105 d2d4ff2a002c5eea46d2ec7f477b78d0 346 Pfam PF16220 Domain of unknown function (DUF4880) 23 61 3.7E-9 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS16105 d2d4ff2a002c5eea46d2ec7f477b78d0 346 Pfam PF16344 Domain of unknown function (DUF4974) 243 337 4.1E-7 T 29-03-2018 IPR032508 Protein FecR, C-terminal CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 82 6.1E-16 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 Gene3D G3DSA:2.40.30.10 103 192 3.9E-19 T 29-03-2018 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 Pfam PF00970 Oxidoreductase FAD-binding domain 106 201 1.4E-12 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 SUPERFAMILY SSF52343 205 338 1.19E-38 T 29-03-2018 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 SUPERFAMILY SSF54292 1 90 1.15E-28 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 304 312 1.3E-7 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 231 1.3E-7 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 155 1.3E-7 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 237 246 1.3E-7 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 132 142 1.3E-7 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 Gene3D G3DSA:3.40.50.80 193 334 1.0E-23 T 29-03-2018 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 2.8E-22 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 196 205 2.8E-22 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 304 312 2.8E-22 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 237 246 2.8E-22 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 212 231 2.8E-22 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 2.8E-22 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 SUPERFAMILY SSF63380 103 203 6.63E-21 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 Pfam PF00175 Oxidoreductase NAD-binding domain 213 318 4.5E-21 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS14550 fecdef64a0e26cd9ef6f37b4c305abbd 348 Gene3D G3DSA:3.10.20.30 1 102 1.3E-24 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS06605 423f927b7389c9de804a62f115794ad5 207 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 197 1.2E-59 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CVS48_RS06605 423f927b7389c9de804a62f115794ad5 207 Gene3D G3DSA:3.40.50.300 3 207 6.6E-27 T 29-03-2018 CVS48_RS06605 423f927b7389c9de804a62f115794ad5 207 SUPERFAMILY SSF52540 7 201 6.91E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06605 423f927b7389c9de804a62f115794ad5 207 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 12 201 25.907 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CVS48_RS06605 423f927b7389c9de804a62f115794ad5 207 Pfam PF01926 50S ribosome-binding GTPase 26 151 1.6E-17 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS13495 cb72963ed9c9df24b171240417168abd 262 Pfam PF00005 ABC transporter 22 176 3.7E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13495 cb72963ed9c9df24b171240417168abd 262 Gene3D G3DSA:3.40.50.300 3 255 9.6E-53 T 29-03-2018 CVS48_RS13495 cb72963ed9c9df24b171240417168abd 262 SUPERFAMILY SSF52540 5 247 2.93E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13495 cb72963ed9c9df24b171240417168abd 262 SMART SM00382 30 224 4.3E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13495 cb72963ed9c9df24b171240417168abd 262 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 246 5.3E-8 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 Pfam PF13609 Gram-negative porin 7 343 2.0E-58 T 29-03-2018 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 SUPERFAMILY SSF56935 21 369 6.72E-72 T 29-03-2018 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 PRINTS PR00184 Neisseria sp. porin signature 56 81 1.8E-9 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 PRINTS PR00184 Neisseria sp. porin signature 156 173 1.8E-9 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 PRINTS PR00184 Neisseria sp. porin signature 323 347 1.8E-9 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 Gene3D G3DSA:2.40.160.10 9 369 7.7E-69 T 29-03-2018 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 54 65 3.9E-8 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 3.9E-8 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 326 343 3.9E-8 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 193 205 3.9E-8 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS17345 912cc065835f9f02c3a47030d10c3c48 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 157 168 3.9E-8 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS10645 09f500eea786e1a1623f5a7cafad7cc2 472 SUPERFAMILY SSF46785 15 83 3.36E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10645 09f500eea786e1a1623f5a7cafad7cc2 472 Gene3D G3DSA:1.10.10.10 20 82 6.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10645 09f500eea786e1a1623f5a7cafad7cc2 472 Gene3D G3DSA:3.40.640.10 134 377 1.5E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS10645 09f500eea786e1a1623f5a7cafad7cc2 472 SUPERFAMILY SSF53383 119 461 4.71E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS10645 09f500eea786e1a1623f5a7cafad7cc2 472 Gene3D G3DSA:3.90.1150.10 378 470 5.4E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS10645 09f500eea786e1a1623f5a7cafad7cc2 472 SMART SM00345 20 79 1.7E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10645 09f500eea786e1a1623f5a7cafad7cc2 472 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 8.0E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10645 09f500eea786e1a1623f5a7cafad7cc2 472 Pfam PF00155 Aminotransferase class I and II 147 455 5.9E-31 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS28440 0bb4c863b7dfd154e71d4b505daf6303 107 Gene3D G3DSA:3.30.70.20 45 106 9.1E-9 T 29-03-2018 CVS48_RS28440 0bb4c863b7dfd154e71d4b505daf6303 107 Gene3D G3DSA:3.30.70.20 2 44 5.3E-12 T 29-03-2018 CVS48_RS28440 0bb4c863b7dfd154e71d4b505daf6303 107 Pfam PF11953 Domain of unknown function (DUF3470) 67 107 4.3E-17 T 29-03-2018 IPR022569 Ferredoxin, C-terminal CVS48_RS28440 0bb4c863b7dfd154e71d4b505daf6303 107 Pfam PF00037 4Fe-4S binding domain 34 56 1.7E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS28440 0bb4c863b7dfd154e71d4b505daf6303 107 SUPERFAMILY SSF54862 1 98 2.93E-23 T 29-03-2018 CVS48_RS28440 0bb4c863b7dfd154e71d4b505daf6303 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS28440 0bb4c863b7dfd154e71d4b505daf6303 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.7E-15 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CVS48_RS28440 0bb4c863b7dfd154e71d4b505daf6303 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.7E-15 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CVS48_RS28440 0bb4c863b7dfd154e71d4b505daf6303 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.7E-15 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1065 13.215 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Gene3D G3DSA:3.40.50.1380 929 1057 1.2E-38 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 SUPERFAMILY SSF48108 403 556 1.57E-54 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Gene3D G3DSA:3.40.50.20 4 117 2.5E-37 T 29-03-2018 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 SUPERFAMILY SSF52335 937 1076 2.09E-38 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 SUPERFAMILY SSF52440 558 677 3.02E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 SMART SM00851 957 1044 5.0E-29 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 387 405 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 304 333 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 175 187 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 211 230 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 246 263 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Pfam PF02142 MGS-like domain 958 1043 9.5E-20 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Gene3D G3DSA:3.30.1490.20 657 745 2.4E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 SUPERFAMILY SSF56059 128 408 2.3E-106 T 29-03-2018 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 2.0E-42 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Gene3D G3DSA:3.30.470.20 119 410 1.3E-66 T 29-03-2018 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 SUPERFAMILY SSF56059 675 935 1.27E-103 T 29-03-2018 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Gene3D G3DSA:1.10.1030.10 411 540 1.6E-53 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Gene3D G3DSA:3.30.470.20 746 928 1.1E-44 T 29-03-2018 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 840 847 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 SMART SM01096 426 549 3.1E-75 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1054 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 304 311 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Gene3D G3DSA:3.40.50.20 541 656 1.2E-61 T 29-03-2018 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 711 725 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1073 13.413 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 SUPERFAMILY SSF52440 1 127 2.01E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 341 2.5E-69 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS13795 e8b27a5c621d3ade54cea0827f42465f 1081 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 876 1.0E-36 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS04235 8c9d07eff6fa1b6d1738fefa4af68ad1 506 Gene3D G3DSA:3.60.120.10 13 497 3.2E-159 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CVS48_RS04235 8c9d07eff6fa1b6d1738fefa4af68ad1 506 PRINTS PR00095 Anthranilate synthase component I signature 429 443 2.8E-22 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS04235 8c9d07eff6fa1b6d1738fefa4af68ad1 506 PRINTS PR00095 Anthranilate synthase component I signature 444 458 2.8E-22 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS04235 8c9d07eff6fa1b6d1738fefa4af68ad1 506 PRINTS PR00095 Anthranilate synthase component I signature 335 348 2.8E-22 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS04235 8c9d07eff6fa1b6d1738fefa4af68ad1 506 PRINTS PR00095 Anthranilate synthase component I signature 349 362 2.8E-22 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS04235 8c9d07eff6fa1b6d1738fefa4af68ad1 506 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 177 8.0E-26 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS04235 8c9d07eff6fa1b6d1738fefa4af68ad1 506 SUPERFAMILY SSF56322 14 495 3.92E-151 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CVS48_RS04235 8c9d07eff6fa1b6d1738fefa4af68ad1 506 Pfam PF00425 chorismate binding enzyme 226 487 2.4E-93 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CVS48_RS04235 8c9d07eff6fa1b6d1738fefa4af68ad1 506 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 495 3.3E-158 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS21235 ae19252ea18b66086db662110cd27c3e 195 Pfam PF08212 Lipocalin-like domain 34 175 1.8E-41 T 29-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain CVS48_RS21235 ae19252ea18b66086db662110cd27c3e 195 PIRSF PIRSF036893 1 184 6.2E-40 T 29-03-2018 IPR022271 Lipocalin, ApoD type CVS48_RS21235 ae19252ea18b66086db662110cd27c3e 195 SUPERFAMILY SSF50814 14 175 9.98E-38 T 29-03-2018 IPR012674 Calycin CVS48_RS21235 ae19252ea18b66086db662110cd27c3e 195 Gene3D G3DSA:2.40.128.20 2 176 2.6E-31 T 29-03-2018 IPR012674 Calycin CVS48_RS21235 ae19252ea18b66086db662110cd27c3e 195 ProSitePatterns PS00213 Lipocalin signature. 33 46 - T 29-03-2018 IPR022272 Lipocalin family conserved site CVS48_RS21235 ae19252ea18b66086db662110cd27c3e 195 PRINTS PR01171 Bacterial lipocalin signature 34 48 1.9E-5 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 CVS48_RS21235 ae19252ea18b66086db662110cd27c3e 195 PRINTS PR01171 Bacterial lipocalin signature 137 148 1.9E-5 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 CVS48_RS21235 ae19252ea18b66086db662110cd27c3e 195 PRINTS PR01171 Bacterial lipocalin signature 122 130 1.9E-5 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 CVS48_RS06485 1d9dff9269fba85b937520fe8ae88c82 250 SUPERFAMILY SSF51197 62 236 7.14E-20 T 29-03-2018 CVS48_RS06485 1d9dff9269fba85b937520fe8ae88c82 250 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 55 210 1.1E-46 T 29-03-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 CVS48_RS06485 1d9dff9269fba85b937520fe8ae88c82 250 Gene3D G3DSA:2.60.120.330 45 228 3.9E-47 T 29-03-2018 IPR027443 Isopenicillin N synthase-like CVS48_RS22145 43c74f7f765ad469854449627af060e3 401 Pfam PF02515 CoA-transferase family III 5 371 3.7E-117 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS22145 43c74f7f765ad469854449627af060e3 401 SUPERFAMILY SSF89796 1 394 2.09E-123 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS22145 43c74f7f765ad469854449627af060e3 401 Gene3D G3DSA:3.40.50.10540 1 401 6.6E-133 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 256 272 1.9E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 256 1.9E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 SUPERFAMILY SSF51215 25 154 1.31E-21 T 29-03-2018 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 Gene3D G3DSA:2.60.120.280 18 179 1.6E-11 T 29-03-2018 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 SUPERFAMILY SSF46689 177 223 2.12E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 SUPERFAMILY SSF46689 225 272 1.84E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 226 268 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 SMART SM00342 189 272 3.2E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 Gene3D G3DSA:1.10.10.60 226 274 4.2E-16 T 29-03-2018 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 Pfam PF02311 AraC-like ligand binding domain 14 143 1.4E-20 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 Pfam PF12833 Helix-turn-helix domain 195 272 2.2E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS04060 e07ed5c4dbe85c124d29e651629ad66d 275 Gene3D G3DSA:1.10.10.60 180 225 1.9E-10 T 29-03-2018 CVS48_RS25625 538f357837c540114b1fa7741caf9251 790 Pfam PF07660 Secretin and TonB N terminus short domain 49 98 1.9E-12 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS25625 538f357837c540114b1fa7741caf9251 790 SUPERFAMILY SSF56935 105 790 1.76E-104 T 29-03-2018 CVS48_RS25625 538f357837c540114b1fa7741caf9251 790 Pfam PF00593 TonB dependent receptor 355 788 1.9E-39 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS25625 538f357837c540114b1fa7741caf9251 790 Gene3D G3DSA:2.170.130.10 103 258 1.1E-19 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS25625 538f357837c540114b1fa7741caf9251 790 Pfam PF07715 TonB-dependent Receptor Plug Domain 144 236 1.7E-11 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS25625 538f357837c540114b1fa7741caf9251 790 Gene3D G3DSA:2.40.170.20 259 790 2.1E-61 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS25625 538f357837c540114b1fa7741caf9251 790 SMART SM00965 49 99 5.7E-14 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS25625 538f357837c540114b1fa7741caf9251 790 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 146 789 3.6E-100 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS10190 d668a92422fdd75a48c8c91f7aff7a07 286 SUPERFAMILY SSF56281 50 273 2.88E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS10190 d668a92422fdd75a48c8c91f7aff7a07 286 SMART SM00849 60 271 6.4E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS10190 d668a92422fdd75a48c8c91f7aff7a07 286 Pfam PF00753 Metallo-beta-lactamase superfamily 60 257 6.3E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS10190 d668a92422fdd75a48c8c91f7aff7a07 286 Gene3D G3DSA:3.60.15.10 24 277 5.7E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 235 4.2E-43 T 29-03-2018 CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 SUPERFAMILY SSF51735 4 238 2.66E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 4.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 4.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 4.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 173 0.0027 T 29-03-2018 CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 Gene3D G3DSA:3.40.50.720 1 241 3.1E-62 T 29-03-2018 CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01605 67db2ba4c29337d7cb80a89c49ad609c 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02865 80aac4afc48466b50b44510cd0f7494a 132 SUPERFAMILY SSF82784 6 122 3.27E-26 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS02865 80aac4afc48466b50b44510cd0f7494a 132 Gene3D G3DSA:3.30.300.20 1 129 3.0E-23 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS02865 80aac4afc48466b50b44510cd0f7494a 132 Pfam PF02566 OsmC-like protein 32 124 2.5E-16 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS10940 51376846bd08a11b9d2066461414c3a6 532 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 477 6.2E-71 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CVS48_RS10940 51376846bd08a11b9d2066461414c3a6 532 SUPERFAMILY SSF103473 25 213 1.83E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS10940 51376846bd08a11b9d2066461414c3a6 532 SUPERFAMILY SSF103473 260 431 1.83E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS10940 51376846bd08a11b9d2066461414c3a6 532 Gene3D G3DSA:1.20.1250.20 10 212 9.3E-32 T 29-03-2018 CVS48_RS10940 51376846bd08a11b9d2066461414c3a6 532 Gene3D G3DSA:1.20.1250.20 263 524 4.4E-30 T 29-03-2018 CVS48_RS10940 51376846bd08a11b9d2066461414c3a6 532 Pfam PF07690 Major Facilitator Superfamily 29 421 2.6E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS19630 6978607516b099e5f7122a3b4efef9bf 433 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 428 2.6E-124 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS19630 6978607516b099e5f7122a3b4efef9bf 433 PIRSF PIRSF006066 5 433 3.8E-88 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS19630 6978607516b099e5f7122a3b4efef9bf 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 422 7.6E-80 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS17660 c0ce4f5268d46a4ee91e5bd055e22339 303 SUPERFAMILY SSF46785 6 109 1.22E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17660 c0ce4f5268d46a4ee91e5bd055e22339 303 Pfam PF03466 LysR substrate binding domain 92 295 8.4E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17660 c0ce4f5268d46a4ee91e5bd055e22339 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.8E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17660 c0ce4f5268d46a4ee91e5bd055e22339 303 Gene3D G3DSA:3.40.190.10 177 269 7.6E-15 T 29-03-2018 CVS48_RS17660 c0ce4f5268d46a4ee91e5bd055e22339 303 Gene3D G3DSA:3.40.190.10 90 176 3.9E-19 T 29-03-2018 CVS48_RS17660 c0ce4f5268d46a4ee91e5bd055e22339 303 Gene3D G3DSA:1.10.10.10 5 83 3.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17660 c0ce4f5268d46a4ee91e5bd055e22339 303 SUPERFAMILY SSF53850 92 298 2.79E-31 T 29-03-2018 CVS48_RS01200 a0833ff8624e2893e01ff4b0ee99fcc4 358 Gene3D G3DSA:3.90.1200.10 117 306 4.5E-31 T 29-03-2018 CVS48_RS01200 a0833ff8624e2893e01ff4b0ee99fcc4 358 Gene3D G3DSA:3.30.200.20 18 116 4.3E-30 T 29-03-2018 CVS48_RS01200 a0833ff8624e2893e01ff4b0ee99fcc4 358 SUPERFAMILY SSF56112 19 322 3.94E-60 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS01200 a0833ff8624e2893e01ff4b0ee99fcc4 358 Pfam PF01636 Phosphotransferase enzyme family 39 289 2.4E-54 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CVS48_RS27390 3c517f80de5d46880fa5dbd6beab2684 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 266 1.7E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27390 3c517f80de5d46880fa5dbd6beab2684 300 SUPERFAMILY SSF161098 14 266 4.32E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27390 3c517f80de5d46880fa5dbd6beab2684 300 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 16 275 1.3E-128 T 29-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 CVS48_RS27390 3c517f80de5d46880fa5dbd6beab2684 300 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 19 273 8.4E-101 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CVS48_RS27390 3c517f80de5d46880fa5dbd6beab2684 300 Gene3D G3DSA:1.10.3720.10 18 280 1.9E-40 T 29-03-2018 CVS48_RS23030 c63a1c3fd2f4cb433b3814e554e918f8 415 Gene3D G3DSA:3.50.50.60 2 414 2.2E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23030 c63a1c3fd2f4cb433b3814e554e918f8 415 SUPERFAMILY SSF51905 1 55 1.07E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23030 c63a1c3fd2f4cb433b3814e554e918f8 415 SUPERFAMILY SSF51905 363 404 1.07E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23030 c63a1c3fd2f4cb433b3814e554e918f8 415 SUPERFAMILY SSF51905 106 271 1.07E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23030 c63a1c3fd2f4cb433b3814e554e918f8 415 Pfam PF01266 FAD dependent oxidoreductase 4 400 1.6E-67 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS23030 c63a1c3fd2f4cb433b3814e554e918f8 415 SUPERFAMILY SSF54373 271 363 5.89E-13 T 29-03-2018 CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 Gene3D G3DSA:1.10.10.10 9 105 3.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 SUPERFAMILY SSF53850 107 309 1.38E-36 T 29-03-2018 CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 SUPERFAMILY SSF46785 15 128 2.24E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 56 2.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 46 2.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 56 67 2.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 Gene3D G3DSA:3.40.190.10 106 193 3.2E-22 T 29-03-2018 CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 79 2.2E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 Gene3D G3DSA:3.40.190.10 194 282 6.2E-16 T 29-03-2018 CVS48_RS19250 80ec559af0a2fac93fb97e8464661cb4 314 Pfam PF03466 LysR substrate binding domain 104 306 2.4E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS01880 9a5fa7b632a83e68cdd83f5934b588a8 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.4E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS01880 9a5fa7b632a83e68cdd83f5934b588a8 396 SUPERFAMILY SSF56645 2 244 1.96E-76 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS01880 9a5fa7b632a83e68cdd83f5934b588a8 396 Gene3D G3DSA:1.20.140.10 219 396 4.4E-38 T 29-03-2018 CVS48_RS01880 9a5fa7b632a83e68cdd83f5934b588a8 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 211 7.5E-23 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS01880 9a5fa7b632a83e68cdd83f5934b588a8 396 Gene3D G3DSA:1.10.540.10 1 120 3.8E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS01880 9a5fa7b632a83e68cdd83f5934b588a8 396 SUPERFAMILY SSF47203 231 396 4.94E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS01880 9a5fa7b632a83e68cdd83f5934b588a8 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 393 7.1E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS01880 9a5fa7b632a83e68cdd83f5934b588a8 396 Gene3D G3DSA:2.40.110.10 121 218 5.6E-37 T 29-03-2018 CVS48_RS04150 35616ab3f494c48b6de732979b300502 862 Pfam PF00577 Outer membrane usher protein 205 757 1.5E-144 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS04150 35616ab3f494c48b6de732979b300502 862 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 319 329 - T 29-03-2018 IPR018030 Fimbrial membrane usher, conserved site CVS48_RS04150 35616ab3f494c48b6de732979b300502 862 Pfam PF13953 PapC C-terminal domain 767 831 2.0E-18 T 29-03-2018 IPR025949 PapC-like, C-terminal domain CVS48_RS04150 35616ab3f494c48b6de732979b300502 862 Pfam PF13954 PapC N-terminal domain 29 188 2.3E-37 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 CVS48_RS04150 35616ab3f494c48b6de732979b300502 862 SUPERFAMILY SSF141729 51 180 3.4E-25 T 29-03-2018 CVS48_RS02945 e521e3f7ba9fe3f6b319d5ed3d323dad 641 SMART SM00763 20 377 2.4E-218 T 29-03-2018 IPR013153 PrkA AAA domain CVS48_RS02945 e521e3f7ba9fe3f6b319d5ed3d323dad 641 Gene3D G3DSA:3.40.50.300 64 350 2.3E-10 T 29-03-2018 CVS48_RS02945 e521e3f7ba9fe3f6b319d5ed3d323dad 641 Pfam PF08298 PrkA AAA domain 21 377 1.1E-173 T 29-03-2018 IPR013153 PrkA AAA domain CVS48_RS02945 e521e3f7ba9fe3f6b319d5ed3d323dad 641 Pfam PF06798 PrkA serine protein kinase C-terminal domain 380 633 1.7E-73 T 29-03-2018 IPR010650 PrkA C-terminal domain CVS48_RS02945 e521e3f7ba9fe3f6b319d5ed3d323dad 641 PIRSF PIRSF000549 1 641 1.8E-294 T 29-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 CVS48_RS02945 e521e3f7ba9fe3f6b319d5ed3d323dad 641 SUPERFAMILY SSF52540 76 346 8.47E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07010 7e5f99a100ec7aed30be73d6abc50c6e 321 SUPERFAMILY SSF53448 3 271 1.69E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS07010 7e5f99a100ec7aed30be73d6abc50c6e 321 Gene3D G3DSA:3.90.550.10 2 299 5.0E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS07010 7e5f99a100ec7aed30be73d6abc50c6e 321 Pfam PF00535 Glycosyl transferase family 2 8 177 1.0E-20 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS22055 083225ffac257078bd6e1a2a21a9d4c6 473 Gene3D G3DSA:1.20.1250.20 22 202 1.1E-22 T 29-03-2018 CVS48_RS22055 083225ffac257078bd6e1a2a21a9d4c6 473 PRINTS PR01035 Tetracycline resistance protein signature 34 50 4.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CVS48_RS22055 083225ffac257078bd6e1a2a21a9d4c6 473 PRINTS PR01035 Tetracycline resistance protein signature 271 291 4.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CVS48_RS22055 083225ffac257078bd6e1a2a21a9d4c6 473 PRINTS PR01035 Tetracycline resistance protein signature 148 170 4.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CVS48_RS22055 083225ffac257078bd6e1a2a21a9d4c6 473 Pfam PF07690 Major Facilitator Superfamily 30 421 1.7E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS22055 083225ffac257078bd6e1a2a21a9d4c6 473 Gene3D G3DSA:1.20.1250.20 270 473 3.1E-9 T 29-03-2018 CVS48_RS22055 083225ffac257078bd6e1a2a21a9d4c6 473 SUPERFAMILY SSF103473 255 471 9.42E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS22055 083225ffac257078bd6e1a2a21a9d4c6 473 SUPERFAMILY SSF103473 26 204 9.42E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS15235 f2c36d27b76df01d253812ddf25180aa 317 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 41 311 1.0E-12 T 29-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CVS48_RS15235 f2c36d27b76df01d253812ddf25180aa 317 Gene3D G3DSA:3.40.630.10 35 298 5.3E-17 T 29-03-2018 CVS48_RS15235 f2c36d27b76df01d253812ddf25180aa 317 SUPERFAMILY SSF53187 15 313 9.08E-49 T 29-03-2018 CVS48_RS18270 d4f0a1b87525d59fcbbc4cd75d0c23fd 336 Gene3D G3DSA:3.40.50.300 5 321 5.2E-69 T 29-03-2018 CVS48_RS18270 d4f0a1b87525d59fcbbc4cd75d0c23fd 336 Pfam PF00005 ABC transporter 29 186 1.1E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS18270 d4f0a1b87525d59fcbbc4cd75d0c23fd 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 321 4.7E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS18270 d4f0a1b87525d59fcbbc4cd75d0c23fd 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 304 3.7E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS18270 d4f0a1b87525d59fcbbc4cd75d0c23fd 336 SUPERFAMILY SSF52540 8 257 5.33E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18270 d4f0a1b87525d59fcbbc4cd75d0c23fd 336 SMART SM00382 37 236 9.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28775 4c2c8182656d2f096d7e518049f66ef5 384 SUPERFAMILY SSF111369 60 272 3.92E-44 T 29-03-2018 CVS48_RS28775 4c2c8182656d2f096d7e518049f66ef5 384 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 268 5.0E-35 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS28775 4c2c8182656d2f096d7e518049f66ef5 384 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 357 2.9E-78 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS28775 4c2c8182656d2f096d7e518049f66ef5 384 Gene3D G3DSA:2.40.50.100 28 100 2.1E-7 T 29-03-2018 CVS48_RS28775 4c2c8182656d2f096d7e518049f66ef5 384 Gene3D G3DSA:1.20.1600.10 104 324 3.3E-21 T 29-03-2018 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 SUPERFAMILY SSF51905 478 539 3.89E-82 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 SUPERFAMILY SSF51905 4 295 3.89E-82 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 PIRSF PIRSF000137 1 543 1.1E-132 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 86 109 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 Gene3D G3DSA:3.30.560.10 108 494 5.4E-94 T 29-03-2018 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 SUPERFAMILY SSF54373 297 479 1.28E-59 T 29-03-2018 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 Gene3D G3DSA:4.10.450.10 40 107 3.5E-26 T 29-03-2018 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 Pfam PF05199 GMC oxidoreductase 395 531 5.0E-39 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 TIGRFAM TIGR01810 betA: choline dehydrogenase 8 541 1.0E-260 T 29-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 261 275 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS10855 d443c24f5ce41889f8160c85f50e3e6b 557 Pfam PF00732 GMC oxidoreductase 7 302 3.0E-91 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS03655 614316aef52fb21476111f73ca252eee 345 Gene3D G3DSA:3.90.180.10 1 162 8.5E-47 T 29-03-2018 CVS48_RS03655 614316aef52fb21476111f73ca252eee 345 SUPERFAMILY SSF50129 4 177 4.87E-51 T 29-03-2018 IPR011032 GroES-like CVS48_RS03655 614316aef52fb21476111f73ca252eee 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 139 5.7E-32 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS03655 614316aef52fb21476111f73ca252eee 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS03655 614316aef52fb21476111f73ca252eee 345 SMART SM00829 8 343 2.2E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS03655 614316aef52fb21476111f73ca252eee 345 Pfam PF00107 Zinc-binding dehydrogenase 179 305 1.9E-21 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS03655 614316aef52fb21476111f73ca252eee 345 Gene3D G3DSA:3.40.50.10730 163 313 4.1E-25 T 29-03-2018 CVS48_RS03655 614316aef52fb21476111f73ca252eee 345 SUPERFAMILY SSF51735 142 310 2.37E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS14000 1d939f19c28844b6f61b3b44d30c13c6 238 Pfam PF01223 DNA/RNA non-specific endonuclease 47 208 3.3E-41 T 29-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 CVS48_RS14000 1d939f19c28844b6f61b3b44d30c13c6 238 Gene3D G3DSA:3.40.570.10 33 238 1.8E-50 T 29-03-2018 CVS48_RS14000 1d939f19c28844b6f61b3b44d30c13c6 238 SMART SM00892 49 238 9.5E-34 T 29-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 CVS48_RS14000 1d939f19c28844b6f61b3b44d30c13c6 238 SUPERFAMILY SSF54060 26 237 7.65E-57 T 29-03-2018 CVS48_RS14000 1d939f19c28844b6f61b3b44d30c13c6 238 SMART SM00477 50 238 7.9E-18 T 29-03-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 CVS48_RS11630 d0dff576f0ad7e662ad774e68bf34fe5 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 318 4.1E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11630 d0dff576f0ad7e662ad774e68bf34fe5 334 PIRSF PIRSF017082 3 331 1.0E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11630 d0dff576f0ad7e662ad774e68bf34fe5 334 SUPERFAMILY SSF53850 125 295 3.98E-11 T 29-03-2018 CVS48_RS11630 d0dff576f0ad7e662ad774e68bf34fe5 334 Gene3D G3DSA:3.40.190.10 136 242 1.3E-12 T 29-03-2018 CVS48_RS20595 b7ec865dc595c4ed2c5e14fa2b7be9ad 309 Pfam PF03466 LysR substrate binding domain 88 294 5.8E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20595 b7ec865dc595c4ed2c5e14fa2b7be9ad 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 6.3E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20595 b7ec865dc595c4ed2c5e14fa2b7be9ad 309 SUPERFAMILY SSF46785 1 110 3.06E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20595 b7ec865dc595c4ed2c5e14fa2b7be9ad 309 Gene3D G3DSA:1.10.10.10 1 85 2.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20595 b7ec865dc595c4ed2c5e14fa2b7be9ad 309 Gene3D G3DSA:3.40.190.10 88 173 1.4E-11 T 29-03-2018 CVS48_RS20595 b7ec865dc595c4ed2c5e14fa2b7be9ad 309 SUPERFAMILY SSF53850 89 297 1.16E-39 T 29-03-2018 CVS48_RS20595 b7ec865dc595c4ed2c5e14fa2b7be9ad 309 Gene3D G3DSA:3.40.190.10 174 263 2.5E-21 T 29-03-2018 CVS48_RS28960 39468a725a897859a8fe1340a8359208 351 SUPERFAMILY SSF55073 178 345 3.92E-34 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS28960 39468a725a897859a8fe1340a8359208 351 SUPERFAMILY SSF55781 19 165 1.74E-16 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS28960 39468a725a897859a8fe1340a8359208 351 Gene3D G3DSA:3.30.450.40 4 162 7.5E-21 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS28960 39468a725a897859a8fe1340a8359208 351 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 171 262 1.2E-30 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS28960 39468a725a897859a8fe1340a8359208 351 SMART SM00065 17 163 3.2E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS28960 39468a725a897859a8fe1340a8359208 351 Gene3D G3DSA:3.30.70.270 163 351 3.1E-45 T 29-03-2018 CVS48_RS28960 39468a725a897859a8fe1340a8359208 351 Pfam PF00990 Diguanylate cyclase, GGDEF domain 173 345 1.0E-33 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS28960 39468a725a897859a8fe1340a8359208 351 Pfam PF13185 GAF domain 17 154 3.9E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS28960 39468a725a897859a8fe1340a8359208 351 SMART SM00267 162 351 2.1E-39 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 PIRSF PIRSF000654 96 173 2.9E-8 T 29-03-2018 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 PIRSF PIRSF000654 17 130 1.2E-13 T 29-03-2018 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 PIRSF PIRSF000654 126 223 2.1E-12 T 29-03-2018 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 Gene3D G3DSA:1.25.40.20 21 102 6.7E-18 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 Gene3D G3DSA:1.20.120.660 103 147 1.6E-14 T 29-03-2018 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 Gene3D G3DSA:1.25.40.20 148 223 3.7E-22 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 PRINTS PR01415 Ankyrin repeat signature 180 194 9.5E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 PRINTS PR01415 Ankyrin repeat signature 127 142 9.5E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 Pfam PF12796 Ankyrin repeats (3 copies) 34 91 1.9E-6 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 Pfam PF12796 Ankyrin repeats (3 copies) 101 195 1.4E-10 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 SUPERFAMILY SSF48403 32 221 3.18E-47 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 SMART SM00248 159 193 150.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 SMART SM00248 60 89 0.0062 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 SMART SM00248 93 122 2700.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 SMART SM00248 197 223 2900.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS12065 6aaa1715d23e732c18c8b9c325086e77 223 SMART SM00248 126 155 0.029 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 SUPERFAMILY SSF50249 421 536 8.0E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 Gene3D G3DSA:3.30.1490.70 364 406 2.1E-10 T 29-03-2018 CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 235 533 2.2E-106 T 29-03-2018 IPR014146 DNA ligase D, ligase domain CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 Gene3D G3DSA:3.30.470.30 194 363 1.4E-33 T 29-03-2018 CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 245 849 7.0E-209 T 29-03-2018 IPR014143 DNA ligase D CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 SUPERFAMILY SSF56091 230 417 6.78E-46 T 29-03-2018 CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 Pfam PF13298 DNA polymerase Ligase (LigD) 36 140 9.8E-38 T 29-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 Pfam PF01068 ATP dependent DNA ligase domain 247 417 3.2E-24 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 Pfam PF04679 ATP dependent DNA ligase C terminal region 436 527 2.1E-23 T 29-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 Gene3D G3DSA:2.40.50.140 407 528 1.8E-30 T 29-03-2018 CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 5 160 3.3E-68 T 29-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 579 822 2.7E-85 T 29-03-2018 IPR014145 DNA ligase D, polymerase domain CVS48_RS18805 cace9f6c907baf86051042bc51f28cc8 867 Pfam PF01896 DNA primase small subunit 696 763 4.4E-6 T 29-03-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 CVS48_RS18505 d9f09ef9727e9d7d87c10923ae929a1c 507 Gene3D G3DSA:3.90.1300.10 3 480 3.2E-124 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS18505 d9f09ef9727e9d7d87c10923ae929a1c 507 Pfam PF01425 Amidase 28 452 3.6E-95 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS18505 d9f09ef9727e9d7d87c10923ae929a1c 507 SUPERFAMILY SSF75304 6 462 3.4E-126 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS05590 3fcceb18d3a2c6ac44f3bc20c304f3e0 163 Gene3D G3DSA:1.10.10.60 68 128 6.7E-15 T 29-03-2018 CVS48_RS05590 3fcceb18d3a2c6ac44f3bc20c304f3e0 163 SUPERFAMILY SSF46689 14 63 3.36E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05590 3fcceb18d3a2c6ac44f3bc20c304f3e0 163 SMART SM00342 30 113 4.8E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS05590 3fcceb18d3a2c6ac44f3bc20c304f3e0 163 SUPERFAMILY SSF46689 66 116 8.51E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05590 3fcceb18d3a2c6ac44f3bc20c304f3e0 163 Pfam PF12833 Helix-turn-helix domain 36 114 5.4E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS05590 3fcceb18d3a2c6ac44f3bc20c304f3e0 163 Gene3D G3DSA:1.10.10.60 10 67 1.6E-15 T 29-03-2018 CVS48_RS21355 89b5a49396796cc9b89eae82b11893e7 207 SUPERFAMILY SSF51182 108 204 3.85E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS21355 89b5a49396796cc9b89eae82b11893e7 207 SUPERFAMILY SSF47413 15 83 2.17E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS21355 89b5a49396796cc9b89eae82b11893e7 207 Pfam PF07883 Cupin domain 145 202 4.2E-11 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS21355 89b5a49396796cc9b89eae82b11893e7 207 Gene3D G3DSA:2.60.120.10 75 207 1.3E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS21355 89b5a49396796cc9b89eae82b11893e7 207 SMART SM00530 23 78 4.7E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS21355 89b5a49396796cc9b89eae82b11893e7 207 Gene3D G3DSA:1.10.260.40 12 74 2.1E-16 T 29-03-2018 CVS48_RS21355 89b5a49396796cc9b89eae82b11893e7 207 Pfam PF13560 Helix-turn-helix domain 20 75 3.1E-12 T 29-03-2018 CVS48_RS06560 aee99031bc8ebf5a66483e17c1571632 133 SUPERFAMILY SSF53137 18 133 9.16E-47 T 29-03-2018 CVS48_RS06560 aee99031bc8ebf5a66483e17c1571632 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 133 32.884 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CVS48_RS06560 aee99031bc8ebf5a66483e17c1571632 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 101 123 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site CVS48_RS06560 aee99031bc8ebf5a66483e17c1571632 133 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 14 130 3.5E-55 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06560 aee99031bc8ebf5a66483e17c1571632 133 PIRSF PIRSF002131 1 133 3.4E-52 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CVS48_RS06560 aee99031bc8ebf5a66483e17c1571632 133 Pfam PF00411 Ribosomal protein S11 23 132 6.6E-50 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CVS48_RS06560 aee99031bc8ebf5a66483e17c1571632 133 Gene3D G3DSA:3.30.420.80 9 133 4.0E-45 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CVS48_RS18430 82dfe3a9366947ca74ab79b8b86e6e49 401 Gene3D G3DSA:3.30.870.10 4 177 5.2E-29 T 29-03-2018 CVS48_RS18430 82dfe3a9366947ca74ab79b8b86e6e49 401 Gene3D G3DSA:3.30.870.10 196 359 6.6E-27 T 29-03-2018 CVS48_RS18430 82dfe3a9366947ca74ab79b8b86e6e49 401 SUPERFAMILY SSF56024 187 343 6.5E-36 T 29-03-2018 CVS48_RS18430 82dfe3a9366947ca74ab79b8b86e6e49 401 SMART SM00155 285 312 11.0 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS18430 82dfe3a9366947ca74ab79b8b86e6e49 401 SMART SM00155 111 138 6.2E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS18430 82dfe3a9366947ca74ab79b8b86e6e49 401 Hamap MF_01917 Cardiolipin synthase B [clsB]. 5 383 48.718 T 29-03-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 CVS48_RS18430 82dfe3a9366947ca74ab79b8b86e6e49 401 SUPERFAMILY SSF56024 6 169 1.47E-38 T 29-03-2018 CVS48_RS18430 82dfe3a9366947ca74ab79b8b86e6e49 401 Pfam PF13091 PLD-like domain 29 158 2.0E-14 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS18430 82dfe3a9366947ca74ab79b8b86e6e49 401 Pfam PF13091 PLD-like domain 216 339 9.2E-26 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS19515 86052fb0e705197a52bff7ccb4fcd720 244 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 9 243 3.8E-114 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CVS48_RS19515 86052fb0e705197a52bff7ccb4fcd720 244 SUPERFAMILY SSF55666 160 243 2.88E-23 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS19515 86052fb0e705197a52bff7ccb4fcd720 244 Pfam PF03725 3' exoribonuclease family, domain 2 165 229 9.5E-12 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS19515 86052fb0e705197a52bff7ccb4fcd720 244 ProSitePatterns PS01277 Ribonuclease PH signature. 123 135 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site CVS48_RS19515 86052fb0e705197a52bff7ccb4fcd720 244 SUPERFAMILY SSF54211 9 188 3.69E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS19515 86052fb0e705197a52bff7ccb4fcd720 244 Pfam PF01138 3' exoribonuclease family, domain 1 17 147 5.4E-20 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS19515 86052fb0e705197a52bff7ccb4fcd720 244 Hamap MF_00564 Ribonuclease PH [rph]. 8 244 48.339 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CVS48_RS19515 86052fb0e705197a52bff7ccb4fcd720 244 Gene3D G3DSA:3.30.230.70 4 244 7.2E-56 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SMART SM00388 1007 1075 3.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SUPERFAMILY SSF52172 1253 1373 3.42E-34 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Pfam PF01739 CheR methyltransferase, SAM binding domain 303 494 1.1E-52 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:3.30.450.20 749 865 6.0E-16 T 29-03-2018 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Pfam PF03705 CheR methyltransferase, all-alpha domain 239 287 8.5E-14 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:3.40.50.180 15 211 1.2E-59 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:1.10.287.130 997 1071 1.8E-15 T 29-03-2018 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Pfam PF01339 CheB methylesterase 24 199 1.3E-48 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SMART SM00091 541 606 2.0 T 29-03-2018 IPR000014 PAS domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SMART SM00091 752 817 6.6 T 29-03-2018 IPR000014 PAS domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SMART SM00091 873 940 6.4E-6 T 29-03-2018 IPR000014 PAS domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SUPERFAMILY SSF47757 238 304 1.22E-11 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SMART SM00448 1255 1368 1.5E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Pfam PF13596 PAS domain 754 859 3.0E-23 T 29-03-2018 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:3.30.450.20 866 987 4.9E-20 T 29-03-2018 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SUPERFAMILY SSF53335 302 498 8.75E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:1.20.5.1000 707 748 3.9E-5 T 29-03-2018 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SUPERFAMILY SSF47384 997 1076 8.24E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Pfam PF13426 PAS domain 886 986 2.3E-10 T 29-03-2018 IPR000014 PAS domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:3.40.50.150 301 501 2.5E-43 T 29-03-2018 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:1.10.155.10 233 299 7.3E-13 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SUPERFAMILY SSF55874 1064 1235 8.77E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 872 989 5.2E-19 T 29-03-2018 IPR000014 PAS domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:3.40.50.2300 1248 1375 4.6E-34 T 29-03-2018 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Pfam PF00072 Response regulator receiver domain 1257 1368 1.1E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1008 1075 2.5E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 PRINTS PR00996 Glutamate methyltransferase family signature 258 271 7.3E-29 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 PRINTS PR00996 Glutamate methyltransferase family signature 295 307 7.3E-29 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 PRINTS PR00996 Glutamate methyltransferase family signature 439 453 7.3E-29 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 PRINTS PR00996 Glutamate methyltransferase family signature 458 481 7.3E-29 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 PRINTS PR00996 Glutamate methyltransferase family signature 337 357 7.3E-29 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 PRINTS PR00996 Glutamate methyltransferase family signature 373 389 7.3E-29 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SUPERFAMILY SSF55785 765 869 1.06E-8 T 29-03-2018 IPR000014 PAS domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SMART SM00138 236 499 5.9E-91 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SMART SM00387 1122 1236 1.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:3.30.565.10 1079 1245 1.0E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Gene3D G3DSA:3.30.450.20 543 706 2.6E-13 T 29-03-2018 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SUPERFAMILY SSF55785 857 982 1.82E-20 T 29-03-2018 IPR000014 PAS domain CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 SUPERFAMILY SSF52738 20 205 1.24E-48 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS25725 1f1ee18b8723342b23cb871818b4d030 1375 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1123 1234 5.4E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS27450 02b9dce1fb861eb8a67484a1012f69f1 302 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 38 56 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CVS48_RS27450 02b9dce1fb861eb8a67484a1012f69f1 302 Gene3D G3DSA:3.40.50.1100 143 302 2.1E-45 T 29-03-2018 CVS48_RS27450 02b9dce1fb861eb8a67484a1012f69f1 302 SUPERFAMILY SSF53686 4 300 1.26E-88 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS27450 02b9dce1fb861eb8a67484a1012f69f1 302 Gene3D G3DSA:3.40.50.1100 46 142 2.5E-35 T 29-03-2018 CVS48_RS27450 02b9dce1fb861eb8a67484a1012f69f1 302 TIGRFAM TIGR01138 cysM: cysteine synthase B 7 301 1.7E-138 T 29-03-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CVS48_RS27450 02b9dce1fb861eb8a67484a1012f69f1 302 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 290 2.5E-63 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS27450 02b9dce1fb861eb8a67484a1012f69f1 302 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 301 3.5E-117 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CVS48_RS18315 568f652f19ea245a808b79b38827ba22 300 Gene3D G3DSA:1.10.3720.10 10 288 1.2E-41 T 29-03-2018 CVS48_RS18315 568f652f19ea245a808b79b38827ba22 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 73 2.2E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS18315 568f652f19ea245a808b79b38827ba22 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 299 3.0E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18315 568f652f19ea245a808b79b38827ba22 300 SUPERFAMILY SSF161098 94 281 1.24E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03175 5b4d29f87b2af949e4e448850fc06727 308 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 1 307 31.407 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CVS48_RS03175 5b4d29f87b2af949e4e448850fc06727 308 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 307 1.5E-82 T 29-03-2018 CVS48_RS03175 5b4d29f87b2af949e4e448850fc06727 308 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 301 2.1E-62 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CVS48_RS03175 5b4d29f87b2af949e4e448850fc06727 308 Gene3D G3DSA:3.40.50.150 106 307 6.5E-31 T 29-03-2018 CVS48_RS03175 5b4d29f87b2af949e4e448850fc06727 308 PIRSF PIRSF000401 1 308 2.3E-84 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CVS48_RS03175 5b4d29f87b2af949e4e448850fc06727 308 SUPERFAMILY SSF53335 90 304 1.12E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 Gene3D G3DSA:3.40.50.10090 8 56 2.8E-11 T 29-03-2018 CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 Gene3D G3DSA:3.40.50.720 57 261 5.1E-68 T 29-03-2018 CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.3E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.3E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.3E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.3E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.3E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.3E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 SUPERFAMILY SSF51735 14 258 5.41E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 184 6.5E-4 T 29-03-2018 CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 257 3.5E-71 T 29-03-2018 CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09290 77b065a4652ad31f54c04c9513a51a2d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS07640 8414a1981fe2606bcddfb86b74a214a2 186 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 31 171 6.6E-23 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CVS48_RS07640 8414a1981fe2606bcddfb86b74a214a2 186 Pfam PF04093 rod shape-determining protein MreD 38 166 3.6E-13 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CVS48_RS07640 8414a1981fe2606bcddfb86b74a214a2 186 PIRSF PIRSF018472 22 180 5.6E-33 T 29-03-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type CVS48_RS23130 45f40b94ab351725f7b406a7ac69d0d9 114 Pfam PF03831 PhnA domain 48 114 8.8E-33 T 29-03-2018 IPR013988 PhnA protein, C-terminal CVS48_RS23130 45f40b94ab351725f7b406a7ac69d0d9 114 SUPERFAMILY SSF57783 4 36 3.06E-14 T 29-03-2018 CVS48_RS23130 45f40b94ab351725f7b406a7ac69d0d9 114 Gene3D G3DSA:2.20.25.10 2 40 5.0E-17 T 29-03-2018 CVS48_RS23130 45f40b94ab351725f7b406a7ac69d0d9 114 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 113 6.2E-47 T 29-03-2018 IPR004624 PhnA protein CVS48_RS23130 45f40b94ab351725f7b406a7ac69d0d9 114 SUPERFAMILY SSF82057 42 114 2.98E-28 T 29-03-2018 CVS48_RS23130 45f40b94ab351725f7b406a7ac69d0d9 114 Pfam PF08274 PhnA Zinc-Ribbon 3 32 1.0E-15 T 29-03-2018 IPR013987 PhnA protein, N-terminal CVS48_RS23130 45f40b94ab351725f7b406a7ac69d0d9 114 Gene3D G3DSA:2.30.30.40 46 113 1.3E-35 T 29-03-2018 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 Gene3D G3DSA:3.40.1770.10 196 555 6.3E-165 T 29-03-2018 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 Gene3D G3DSA:3.40.1770.10 10 152 2.0E-29 T 29-03-2018 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 PIRSF PIRSF001423 2 559 1.1E-296 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 Pfam PF17391 Urocanase N-terminal domain 12 138 4.3E-62 T 29-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 Pfam PF17392 Urocanase C-terminal domain 352 546 3.7E-93 T 29-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 Hamap MF_00577 Urocanate hydratase [hutU]. 2 556 50.712 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 SUPERFAMILY SSF111326 7 555 1.44E-262 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 Pfam PF01175 Urocanase Rossmann-like domain 141 349 9.7E-87 T 29-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 TIGRFAM TIGR01228 hutU: urocanate hydratase 12 554 0.0 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04470 7c7ef4ce5b433b9838ef5816662ffd12 559 ProSitePatterns PS01233 Urocanase signature. 442 457 - T 29-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS14140 40887a5f07ebb91cd23ec9d3f30020cc 399 Gene3D G3DSA:3.40.50.2300 176 346 4.1E-30 T 29-03-2018 CVS48_RS14140 40887a5f07ebb91cd23ec9d3f30020cc 399 Pfam PF13458 Periplasmic binding protein 27 381 7.5E-60 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS14140 40887a5f07ebb91cd23ec9d3f30020cc 399 Gene3D G3DSA:3.40.50.2300 22 175 1.2E-30 T 29-03-2018 CVS48_RS14140 40887a5f07ebb91cd23ec9d3f30020cc 399 SUPERFAMILY SSF53822 27 389 4.37E-74 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 Gene3D G3DSA:2.40.50.140 650 745 2.0E-25 T 29-03-2018 CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 Pfam PF00575 S1 RNA binding domain 670 739 1.0E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 Gene3D G3DSA:1.10.3500.10 372 517 1.2E-37 T 29-03-2018 IPR023323 Tex-like domain CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 SUPERFAMILY SSF158832 17 339 2.22E-109 T 29-03-2018 CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 SUPERFAMILY SSF53098 340 488 4.4E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 Pfam PF09371 Tex-like protein N-terminal domain 23 206 8.1E-67 T 29-03-2018 IPR018974 Tex-like protein, N-terminal CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 SUPERFAMILY SSF47781 579 651 6.67E-19 T 29-03-2018 IPR010994 RuvA domain 2-like CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 SMART SM00316 668 739 2.2E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 Gene3D G3DSA:1.10.150.310 518 649 9.7E-42 T 29-03-2018 CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 Gene3D G3DSA:1.10.10.650 16 116 1.0E-31 T 29-03-2018 IPR023319 Tex-like protein, HTH domain CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 Gene3D G3DSA:1.10.3500.10 117 371 1.1E-73 T 29-03-2018 IPR023323 Tex-like domain CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 Pfam PF12836 Helix-hairpin-helix motif 510 574 9.0E-25 T 29-03-2018 CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 SUPERFAMILY SSF47781 489 577 1.22E-26 T 29-03-2018 IPR010994 RuvA domain 2-like CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 SMART SM00732 344 443 2.9E-38 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 SUPERFAMILY SSF50249 657 744 2.01E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS27705 c20f0359ef5cfa8a7415a6f241969599 792 Pfam PF16921 Tex protein YqgF-like domain 344 470 2.7E-52 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 SMART SM00422 2 71 1.6E-27 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 Gene3D G3DSA:1.10.1660.10 58 132 1.7E-18 T 29-03-2018 CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 Gene3D G3DSA:1.10.1660.10 1 57 5.6E-20 T 29-03-2018 CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 SUPERFAMILY SSF46955 2 128 2.23E-32 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 2 128 1.3E-51 T 29-03-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 Pfam PF00376 MerR family regulatory protein 3 40 1.3E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 4.4E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 4.4E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 4.4E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00920 201f56cb0332c48dd4d809a079547a8b 132 Pfam PF09278 MerR, DNA binding 45 109 1.6E-18 T 29-03-2018 IPR015358 Transcription regulator MerR, DNA binding CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 SUPERFAMILY SSF48452 227 401 1.05E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Gene3D G3DSA:1.25.40.10 568 625 6.9E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Gene3D G3DSA:1.25.40.10 99 274 7.7E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Gene3D G3DSA:1.25.40.10 347 388 3.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Gene3D G3DSA:1.25.40.10 521 567 4.7E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Gene3D G3DSA:1.25.40.10 279 346 4.5E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Pfam PF13432 Tetratricopeptide repeat 483 548 2.5E-9 T 29-03-2018 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Pfam PF13432 Tetratricopeptide repeat 204 260 0.017 T 29-03-2018 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 SMART SM00028 227 260 34.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 SMART SM00028 479 512 12.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 SMART SM00028 548 581 24.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 SMART SM00028 328 361 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 SMART SM00028 513 547 10.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 SMART SM00028 582 614 78.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 SUPERFAMILY SSF48452 449 615 9.1E-26 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Pfam PF14559 Tetratricopeptide repeat 305 362 1.8E-5 T 29-03-2018 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Pfam PF14559 Tetratricopeptide repeat 561 622 4.9E-8 T 29-03-2018 CVS48_RS10830 8960542c7b5df47d183b79168d18ac81 628 Gene3D G3DSA:1.25.40.10 389 520 2.1E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS20920 303f982d17e34303cc0345c8e87dd91d 327 SUPERFAMILY SSF53850 113 287 4.89E-9 T 29-03-2018 CVS48_RS20920 303f982d17e34303cc0345c8e87dd91d 327 Gene3D G3DSA:3.40.190.10 127 237 8.1E-11 T 29-03-2018 CVS48_RS20920 303f982d17e34303cc0345c8e87dd91d 327 PIRSF PIRSF017082 1 327 2.9E-66 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS20920 303f982d17e34303cc0345c8e87dd91d 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 2.4E-67 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS05980 7463aaa7e0b99a6f9591dd19c0bfd564 244 PIRSF PIRSF039085 1 243 3.9E-98 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS05980 7463aaa7e0b99a6f9591dd19c0bfd564 244 Gene3D G3DSA:3.40.50.300 1 241 3.6E-67 T 29-03-2018 CVS48_RS05980 7463aaa7e0b99a6f9591dd19c0bfd564 244 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05980 7463aaa7e0b99a6f9591dd19c0bfd564 244 Pfam PF00005 ABC transporter 17 165 8.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05980 7463aaa7e0b99a6f9591dd19c0bfd564 244 SUPERFAMILY SSF52540 1 228 1.2E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05980 7463aaa7e0b99a6f9591dd19c0bfd564 244 SMART SM00382 26 213 2.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 Gene3D G3DSA:4.10.320.10 123 176 4.7E-17 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 Gene3D G3DSA:3.90.1170.30 2 48 6.3E-15 T 29-03-2018 CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 Pfam PF00364 Biotin-requiring enzyme 4 77 2.9E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 SUPERFAMILY SSF47005 120 165 1.15E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 Gene3D G3DSA:2.40.50.100 49 122 0.04 T 29-03-2018 CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 Pfam PF02817 e3 binding domain 127 161 7.9E-14 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 SUPERFAMILY SSF51230 2 93 4.06E-26 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 Gene3D G3DSA:3.30.559.10 177 417 2.3E-79 T 29-03-2018 CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 SUPERFAMILY SSF52777 190 417 7.56E-74 T 29-03-2018 CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CVS48_RS08920 d0251182150444f9c3438eb2e81b33a1 417 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 192 416 1.9E-76 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 SMART SM00436 122 217 1.9E-35 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 SMART SM00493 1 122 2.7E-25 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 SUPERFAMILY SSF57783 622 656 1.67E-9 T 29-03-2018 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 Pfam PF01751 Toprim domain 3 128 1.5E-16 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 623 657 8.9E-10 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 653 6.4E-215 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 308 323 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 SMART SM00437 271 561 1.8E-61 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 Gene3D G3DSA:1.10.460.10 485 615 2.5E-15 T 29-03-2018 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 524 538 6.0E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 187 205 6.0E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 314 323 6.0E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 96 109 6.0E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 395 411 6.0E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 Pfam PF01131 DNA topoisomerase 151 592 5.9E-110 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 Gene3D G3DSA:3.30.65.10 616 666 1.9E-14 T 29-03-2018 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 Gene3D G3DSA:2.70.20.10 362 484 2.0E-19 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 Gene3D G3DSA:1.10.460.10 151 361 7.9E-40 T 29-03-2018 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 Gene3D G3DSA:3.40.50.140 1 150 2.8E-40 T 29-03-2018 CVS48_RS00935 896716f46bfb543eb7064207e19e7d82 676 SUPERFAMILY SSF56712 1 608 7.85E-178 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CVS48_RS17330 793b3e7a618db309c9bc87e215aa47e2 260 Gene3D G3DSA:3.40.50.300 6 259 1.0E-71 T 29-03-2018 CVS48_RS17330 793b3e7a618db309c9bc87e215aa47e2 260 SUPERFAMILY SSF52540 10 249 1.54E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS17330 793b3e7a618db309c9bc87e215aa47e2 260 Pfam PF00005 ABC transporter 26 179 2.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS17330 793b3e7a618db309c9bc87e215aa47e2 260 SMART SM00382 35 227 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS17330 793b3e7a618db309c9bc87e215aa47e2 260 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS17330 793b3e7a618db309c9bc87e215aa47e2 260 PIRSF PIRSF039085 7 255 2.4E-109 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 629 1.3E-268 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 Gene3D G3DSA:3.50.50.60 5 264 2.5E-75 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 SMART SM01228 554 625 3.6E-42 T 29-03-2018 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 Pfam PF01134 Glucose inhibited division protein A 8 399 8.4E-165 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 SUPERFAMILY SSF51905 6 66 1.19E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 SUPERFAMILY SSF51905 97 262 1.19E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 632 42.695 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CVS48_RS06150 f494fdedea48529016bbdbf3d0add1e5 639 Pfam PF13932 GidA associated domain 403 624 1.1E-75 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 PIRSF PIRSF000116 201 331 2.0E-12 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 PIRSF PIRSF000116 2 204 4.7E-46 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 Gene3D G3DSA:3.90.180.10 10 76 4.2E-4 T 29-03-2018 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.178 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 1.3E-73 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 2.6E-134 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 SUPERFAMILY SSF48179 183 332 9.35E-69 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 Gene3D G3DSA:1.10.1040.10 77 330 1.4E-110 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 1.2E-63 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS29120 b8731b817983f4c4b2d0b8707e8d13a0 338 SUPERFAMILY SSF51735 1 182 1.18E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 PIRSF PIRSF000116 201 331 2.0E-12 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 PIRSF PIRSF000116 2 204 4.7E-46 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 Gene3D G3DSA:3.90.180.10 10 76 4.2E-4 T 29-03-2018 CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.178 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 1.3E-73 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 2.6E-134 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 SUPERFAMILY SSF48179 183 332 9.35E-69 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 Gene3D G3DSA:1.10.1040.10 77 330 1.4E-110 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 1.2E-63 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CVS48_RS00065 b8731b817983f4c4b2d0b8707e8d13a0 338 SUPERFAMILY SSF51735 1 182 1.18E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 899 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 Gene3D G3DSA:3.20.19.10 654 900 9.2E-88 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 Gene3D G3DSA:3.30.499.10 34 237 1.1E-69 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 ProSitePatterns PS00450 Aconitase family signature 1. 429 445 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 Pfam PF00694 Aconitase C-terminal domain 693 825 2.4E-40 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 Gene3D G3DSA:3.40.1060.10 238 370 7.7E-45 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 PRINTS PR00415 Aconitase family signature 146 159 1.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 PRINTS PR00415 Aconitase family signature 371 385 1.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 PRINTS PR00415 Aconitase family signature 291 304 1.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 PRINTS PR00415 Aconitase family signature 433 444 1.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 PRINTS PR00415 Aconitase family signature 170 178 1.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 PRINTS PR00415 Aconitase family signature 495 508 1.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 PRINTS PR00415 Aconitase family signature 277 290 1.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 PRINTS PR00415 Aconitase family signature 201 214 1.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 PRINTS PR00415 Aconitase family signature 215 230 1.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 Pfam PF00330 Aconitase family (aconitate hydratase) 69 564 2.6E-177 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 ProSitePatterns PS01244 Aconitase family signature 2. 495 508 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 SUPERFAMILY SSF52016 637 899 2.55E-83 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 Gene3D G3DSA:3.30.499.10 371 578 8.2E-64 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23530 a4d019fdae31d1e30ca8ccee8324ff4a 901 SUPERFAMILY SSF53732 4 618 8.63E-214 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 Gene3D G3DSA:3.30.1360.120 137 236 4.8E-19 T 29-03-2018 CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 Gene3D G3DSA:3.30.1360.120 5 136 1.1E-33 T 29-03-2018 CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 Gene3D G3DSA:4.10.1250.10 237 278 5.3E-15 T 29-03-2018 CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 359 4.8E-119 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 SUPERFAMILY SSF101790 282 361 9.16E-22 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 359 42.88 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 353 1.5E-13 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 PIRSF PIRSF006487 1 366 1.1E-79 T 29-03-2018 CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 258 2.0E-85 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 Gene3D G3DSA:2.40.30.110 282 366 3.4E-20 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CVS48_RS10580 6d350509b4aa81f5b97e6bbf2149335c 366 SUPERFAMILY SSF103025 5 277 8.24E-91 T 29-03-2018 CVS48_RS11180 e04545c215075dae0432133c1eece46a 245 Pfam PF01614 Bacterial transcriptional regulator 123 237 4.7E-13 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS11180 e04545c215075dae0432133c1eece46a 245 Pfam PF09339 IclR helix-turn-helix domain 8 56 3.4E-7 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS11180 e04545c215075dae0432133c1eece46a 245 Gene3D G3DSA:1.10.10.10 3 65 3.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11180 e04545c215075dae0432133c1eece46a 245 SUPERFAMILY SSF55781 78 240 3.92E-26 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS11180 e04545c215075dae0432133c1eece46a 245 SUPERFAMILY SSF46785 6 73 6.47E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11180 e04545c215075dae0432133c1eece46a 245 Gene3D G3DSA:3.30.450.40 72 242 1.4E-26 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 Gene3D G3DSA:3.40.50.10090 7 52 2.0E-9 T 29-03-2018 CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.4E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.4E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.4E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 199 0.0023 T 29-03-2018 CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 Gene3D G3DSA:3.40.50.720 53 259 3.0E-59 T 29-03-2018 CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 SUPERFAMILY SSF51735 10 257 8.75E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS05745 04a661ea33fbbe2a2fac39587b1f99fd 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 256 2.3E-61 T 29-03-2018 CVS48_RS22245 94023ec62dc164b659c05daa5373f1fd 321 SMART SM00904 192 317 1.6E-51 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CVS48_RS22245 94023ec62dc164b659c05daa5373f1fd 321 Pfam PF01687 Riboflavin kinase 193 316 2.6E-32 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CVS48_RS22245 94023ec62dc164b659c05daa5373f1fd 321 PIRSF PIRSF004491 5 320 4.9E-93 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CVS48_RS22245 94023ec62dc164b659c05daa5373f1fd 321 Pfam PF06574 FAD synthetase 17 175 6.8E-50 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CVS48_RS22245 94023ec62dc164b659c05daa5373f1fd 321 Gene3D G3DSA:3.40.50.620 5 188 9.8E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS22245 94023ec62dc164b659c05daa5373f1fd 321 SUPERFAMILY SSF82114 184 317 2.83E-37 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CVS48_RS22245 94023ec62dc164b659c05daa5373f1fd 321 Gene3D G3DSA:2.40.30.30 189 321 1.4E-34 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CVS48_RS22245 94023ec62dc164b659c05daa5373f1fd 321 SUPERFAMILY SSF52374 19 188 5.3E-30 T 29-03-2018 CVS48_RS22245 94023ec62dc164b659c05daa5373f1fd 321 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 316 5.3E-87 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CVS48_RS28405 ef431306d1ed49d4eae8646145f7485c 383 SUPERFAMILY SSF53187 306 380 4.86E-59 T 29-03-2018 CVS48_RS28405 ef431306d1ed49d4eae8646145f7485c 383 SUPERFAMILY SSF53187 4 175 4.86E-59 T 29-03-2018 CVS48_RS28405 ef431306d1ed49d4eae8646145f7485c 383 Gene3D G3DSA:3.30.70.360 179 308 9.2E-26 T 29-03-2018 CVS48_RS28405 ef431306d1ed49d4eae8646145f7485c 383 Pfam PF01546 Peptidase family M20/M25/M40 69 379 1.1E-39 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS28405 ef431306d1ed49d4eae8646145f7485c 383 SUPERFAMILY SSF55031 177 283 6.28E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS28405 ef431306d1ed49d4eae8646145f7485c 383 Pfam PF07687 Peptidase dimerisation domain 172 282 1.3E-24 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS28405 ef431306d1ed49d4eae8646145f7485c 383 Gene3D G3DSA:3.40.630.10 1 178 1.4E-32 T 29-03-2018 CVS48_RS28405 ef431306d1ed49d4eae8646145f7485c 383 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 7 379 6.7E-122 T 29-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 CVS48_RS28405 ef431306d1ed49d4eae8646145f7485c 383 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 102 139 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CVS48_RS13985 548babd4c20c018d9f06749feb3d2fb4 168 Pfam PF05974 Domain of unknown function (DUF892) 5 162 1.0E-61 T 29-03-2018 IPR010287 Domain of unknown function DUF892 CVS48_RS13985 548babd4c20c018d9f06749feb3d2fb4 168 SUPERFAMILY SSF47240 1 152 1.95E-55 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS13985 548babd4c20c018d9f06749feb3d2fb4 168 Gene3D G3DSA:1.20.1260.10 1 165 2.6E-30 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS23970 8e73a55b6022ad32906f23f27401227c 389 SUPERFAMILY SSF89796 6 380 2.22E-134 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS23970 8e73a55b6022ad32906f23f27401227c 389 Pfam PF02515 CoA-transferase family III 7 373 4.1E-129 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS23970 8e73a55b6022ad32906f23f27401227c 389 Gene3D G3DSA:3.40.50.10540 1 385 2.1E-147 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 Gene3D G3DSA:3.30.565.10 234 397 2.6E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 277 395 1.7E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 SMART SM00388 167 235 1.5E-5 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 Pfam PF00072 Response regulator receiver domain 421 527 7.0E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 SUPERFAMILY SSF52172 418 531 8.11E-23 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 Gene3D G3DSA:3.30.450.20 31 152 1.4E-12 T 29-03-2018 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 SUPERFAMILY SSF47384 157 232 1.28E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 Gene3D G3DSA:1.10.287.130 153 231 6.5E-8 T 29-03-2018 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 SUPERFAMILY SSF55785 38 132 4.19E-7 T 29-03-2018 IPR000014 PAS domain CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 SMART SM00448 419 527 1.0E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 Gene3D G3DSA:3.40.50.2300 413 533 2.3E-20 T 29-03-2018 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 SUPERFAMILY SSF55874 226 396 1.02E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 Pfam PF08448 PAS fold 41 142 8.0E-6 T 29-03-2018 IPR013656 PAS fold-4 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 Pfam PF00512 His Kinase A (phospho-acceptor) domain 168 232 5.3E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 SMART SM00387 276 398 6.2E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 395 3.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 376 3.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 341 3.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12230 6af31e2495ddbb078da9aa0f63091e3e 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 355 3.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 588 1.4E-241 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 Gene3D G3DSA:3.30.930.10 131 592 4.2E-105 T 29-03-2018 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 Gene3D G3DSA:2.40.50.140 1 107 2.0E-24 T 29-03-2018 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 Pfam PF02938 GAD domain 309 406 4.2E-27 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 564 6.7E-107 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 1.4E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 480 496 1.4E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 524 538 1.4E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 1.4E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 Pfam PF01336 OB-fold nucleic acid binding domain 18 101 2.0E-17 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 590 33.527 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 SUPERFAMILY SSF55681 430 590 7.56E-103 T 29-03-2018 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 SUPERFAMILY SSF55681 110 292 7.56E-103 T 29-03-2018 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 SUPERFAMILY SSF55261 291 416 1.96E-41 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CVS48_RS06945 eabfbacf956b9deeaf41b7cd4bd4024f 594 SUPERFAMILY SSF50249 1 104 2.48E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS07500 9deb77c934b8ed986ac3cb996a2ea0a8 149 SUPERFAMILY SSF55729 4 134 5.57E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS07500 9deb77c934b8ed986ac3cb996a2ea0a8 149 Pfam PF00583 Acetyltransferase (GNAT) family 44 134 2.5E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS07500 9deb77c934b8ed986ac3cb996a2ea0a8 149 Gene3D G3DSA:3.40.630.30 1 146 2.3E-26 T 29-03-2018 CVS48_RS22600 3155aa6cb97a09a52a4d25ee97e9d2e3 251 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 246 8.0E-115 T 29-03-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 CVS48_RS22600 3155aa6cb97a09a52a4d25ee97e9d2e3 251 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 50 246 2.7E-60 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS22600 3155aa6cb97a09a52a4d25ee97e9d2e3 251 SUPERFAMILY SSF56529 38 246 6.41E-73 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS22600 3155aa6cb97a09a52a4d25ee97e9d2e3 251 Gene3D G3DSA:3.90.850.10 34 250 1.2E-71 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS22600 3155aa6cb97a09a52a4d25ee97e9d2e3 251 Gene3D G3DSA:2.30.30.370 1 33 8.0E-19 T 29-03-2018 CVS48_RS24930 00b2202b34a6e1c33e02f296435a2a5e 429 Gene3D G3DSA:1.20.1250.20 227 419 1.1E-25 T 29-03-2018 CVS48_RS24930 00b2202b34a6e1c33e02f296435a2a5e 429 SUPERFAMILY SSF103473 9 416 1.23E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS24930 00b2202b34a6e1c33e02f296435a2a5e 429 Gene3D G3DSA:1.20.1250.20 9 200 8.9E-16 T 29-03-2018 CVS48_RS24930 00b2202b34a6e1c33e02f296435a2a5e 429 Pfam PF07690 Major Facilitator Superfamily 22 326 4.1E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS02590 541b1fac1a7fe5480c53c3c10f43e8fd 262 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 253 4.0E-85 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CVS48_RS02590 541b1fac1a7fe5480c53c3c10f43e8fd 262 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 260 1.7E-83 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CVS48_RS02590 541b1fac1a7fe5480c53c3c10f43e8fd 262 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 139 151 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CVS48_RS02590 541b1fac1a7fe5480c53c3c10f43e8fd 262 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 260 20.504 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 155 183 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 SUPERFAMILY SSF51161 49 345 1.0E-76 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 Gene3D G3DSA:2.160.10.10 159 335 1.0E-46 T 29-03-2018 CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 38 358 2.1E-106 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 229 245 0.25 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 288 321 1.3E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 39 112 7.8E-22 T 29-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 251 286 2.5E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 171 204 3.5E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 134 168 6.0E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 9 355 36.568 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CVS48_RS17170 5e80b176f9f6f64e4f8ea714ba98dcc9 365 Gene3D G3DSA:2.160.10.10 122 158 1.1E-10 T 29-03-2018 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 7.6E-35 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 57 72 7.6E-35 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 7.6E-35 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 78 98 7.6E-35 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 146 172 7.6E-35 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 27 52 7.6E-35 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 Gene3D G3DSA:2.102.10.10 40 151 6.9E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 Pfam PF00355 Rieske [2Fe-2S] domain 42 126 5.1E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 197 434 1.3E-13 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 SUPERFAMILY SSF50022 10 161 8.51E-42 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 SUPERFAMILY SSF55961 162 436 3.45E-55 T 29-03-2018 CVS48_RS01575 b161540a5fd84776e60b76ab33d76bd9 439 Gene3D G3DSA:3.90.380.10 152 439 1.3E-61 T 29-03-2018 CVS48_RS22645 4a93d42b0a57c5331eadeec10806541e 208 Pfam PF16357 Putative PepSY_TM-like 12 208 5.2E-87 T 29-03-2018 IPR032307 Putative PepSY TM-like protein CVS48_RS26305 035812b968f8aaac73d16c51da6e499b 397 Pfam PF07969 Amidohydrolase family 40 387 7.2E-28 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS26305 035812b968f8aaac73d16c51da6e499b 397 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 52 60 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CVS48_RS26305 035812b968f8aaac73d16c51da6e499b 397 SUPERFAMILY SSF51338 348 392 2.16E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS26305 035812b968f8aaac73d16c51da6e499b 397 SUPERFAMILY SSF51338 3 51 2.16E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS26305 035812b968f8aaac73d16c51da6e499b 397 Gene3D G3DSA:2.30.40.10 1 63 4.1E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS26305 035812b968f8aaac73d16c51da6e499b 397 Gene3D G3DSA:3.20.20.140 64 368 9.7E-31 T 29-03-2018 CVS48_RS26305 035812b968f8aaac73d16c51da6e499b 397 SUPERFAMILY SSF51556 51 357 2.49E-73 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 SUPERFAMILY SSF81464 29 122 1.96E-25 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 Gene3D G3DSA:2.60.40.420 125 258 1.4E-47 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 128 253 6.6E-39 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 Gene3D G3DSA:1.10.287.90 30 123 4.1E-24 T 29-03-2018 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 SUPERFAMILY SSF46626 275 370 2.88E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 199 247 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 102 122 3.5E-40 T 29-03-2018 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 90 102 3.5E-40 T 29-03-2018 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 198 218 3.5E-40 T 29-03-2018 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 174 195 3.5E-40 T 29-03-2018 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 124 143 3.5E-40 T 29-03-2018 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 236 253 3.5E-40 T 29-03-2018 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 218 235 3.5E-40 T 29-03-2018 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 Gene3D G3DSA:1.10.760.10 259 368 1.6E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 31 113 1.8E-13 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 42 264 4.6E-58 T 29-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 286 360 9.1E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 SUPERFAMILY SSF49503 176 317 5.17E-54 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS04975 ddae8c5a76697048b95f47d970444ad5 385 SUPERFAMILY SSF49503 120 147 5.17E-54 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 Pfam PF00196 Bacterial regulatory proteins, luxR family 185 233 4.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 Gene3D G3DSA:1.10.10.10 145 240 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 Gene3D G3DSA:3.40.50.2300 17 144 1.4E-23 T 29-03-2018 CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 SMART SM00448 18 133 2.3E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 Pfam PF00072 Response regulator receiver domain 20 133 3.3E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 200 1.9E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 228 1.9E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 216 1.9E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 SUPERFAMILY SSF46894 183 238 2.28E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 SUPERFAMILY SSF52172 17 148 4.41E-22 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS02910 b2bb4c655130167f3e1826a8480b54c0 243 SMART SM00421 183 240 1.9E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 Pfam PF12848 ABC transporter 233 309 1.6E-12 T 29-03-2018 IPR032781 ABC-transporter extension domain CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 SUPERFAMILY SSF52540 305 533 1.83E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 556 1.9E-292 T 29-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 Gene3D G3DSA:3.40.50.300 293 554 2.6E-61 T 29-03-2018 CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 Pfam PF00005 ABC transporter 343 476 1.4E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 Pfam PF00005 ABC transporter 22 194 6.9E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 SMART SM00382 31 245 2.3E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 SMART SM00382 351 529 6.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 Gene3D G3DSA:3.40.50.300 12 292 2.0E-53 T 29-03-2018 CVS48_RS01515 112de10d3bf4c6ff1645e7e0fdb76e4c 557 SUPERFAMILY SSF52540 12 239 3.38E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 SUPERFAMILY SSF46785 3 87 4.14E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 Gene3D G3DSA:3.40.190.10 89 177 3.5E-20 T 29-03-2018 CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.8E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 Gene3D G3DSA:1.10.10.10 1 83 4.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.4E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.4E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.4E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 SUPERFAMILY SSF53850 88 295 1.63E-35 T 29-03-2018 CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 Gene3D G3DSA:3.40.190.10 178 294 1.1E-26 T 29-03-2018 CVS48_RS19785 529bc934bdbe463a64dc1e4eef64656b 298 Pfam PF03466 LysR substrate binding domain 88 295 8.0E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS27335 3d1288790fc174f3c1ddc86ca27b13a1 318 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 23 315 34.22 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CVS48_RS27335 3d1288790fc174f3c1ddc86ca27b13a1 318 Pfam PF03193 RsgA GTPase 77 250 6.6E-47 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CVS48_RS27335 3d1288790fc174f3c1ddc86ca27b13a1 318 Gene3D G3DSA:2.40.50.140 18 79 3.5E-16 T 29-03-2018 CVS48_RS27335 3d1288790fc174f3c1ddc86ca27b13a1 318 Gene3D G3DSA:3.40.50.300 89 250 1.0E-20 T 29-03-2018 CVS48_RS27335 3d1288790fc174f3c1ddc86ca27b13a1 318 Gene3D G3DSA:1.10.40.50 252 318 9.7E-20 T 29-03-2018 CVS48_RS27335 3d1288790fc174f3c1ddc86ca27b13a1 318 SUPERFAMILY SSF52540 94 310 7.02E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27335 3d1288790fc174f3c1ddc86ca27b13a1 318 SUPERFAMILY SSF50249 23 80 1.11E-7 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS27335 3d1288790fc174f3c1ddc86ca27b13a1 318 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 58 309 1.4E-58 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CVS48_RS05160 a66dcc26f6c5888ebe040b01141e3bc2 129 SMART SM00530 6 64 4.4E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS05160 a66dcc26f6c5888ebe040b01141e3bc2 129 Pfam PF13560 Helix-turn-helix domain 4 61 2.8E-8 T 29-03-2018 CVS48_RS05160 a66dcc26f6c5888ebe040b01141e3bc2 129 Gene3D G3DSA:1.10.260.40 1 73 1.3E-11 T 29-03-2018 CVS48_RS05160 a66dcc26f6c5888ebe040b01141e3bc2 129 SUPERFAMILY SSF47413 3 66 6.52E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS08090 083da9d58658e96c70f1fdcc3dd2ee04 252 Pfam PF01614 Bacterial transcriptional regulator 123 244 2.7E-24 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS08090 083da9d58658e96c70f1fdcc3dd2ee04 252 SUPERFAMILY SSF46785 7 78 1.24E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08090 083da9d58658e96c70f1fdcc3dd2ee04 252 SMART SM00346 7 99 0.0018 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS08090 083da9d58658e96c70f1fdcc3dd2ee04 252 Gene3D G3DSA:3.30.450.40 74 248 1.7E-37 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS08090 083da9d58658e96c70f1fdcc3dd2ee04 252 Gene3D G3DSA:1.10.10.10 2 73 3.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08090 083da9d58658e96c70f1fdcc3dd2ee04 252 Pfam PF09339 IclR helix-turn-helix domain 9 59 1.4E-9 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS08090 083da9d58658e96c70f1fdcc3dd2ee04 252 SUPERFAMILY SSF55781 72 245 2.42E-35 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 SUPERFAMILY SSF51735 7 257 1.79E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 Gene3D G3DSA:3.40.50.720 1 258 3.8E-52 T 29-03-2018 CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 5.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.2E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.2E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.2E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13950 b8d7f784ca1aa9e619ceb1913453f3d2 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 256 2.0E-36 T 29-03-2018 CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 24 249 3.7E-117 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 SUPERFAMILY SSF46785 271 344 8.16E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 Gene3D G3DSA:1.10.10.10 271 341 1.2E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 37 340 4.3E-145 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 357 179.782 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 SMART SM00382 65 193 2.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 267 340 3.8E-33 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 Gene3D G3DSA:1.10.8.60 198 268 1.1E-29 T 29-03-2018 CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 Gene3D G3DSA:3.40.50.300 32 195 5.3E-29 T 29-03-2018 CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 SUPERFAMILY SSF52540 34 264 4.95E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01440 c10d66bb17294801aa88add3cb92c9e7 357 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 264 338 1.0E-36 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CVS48_RS05205 2d8cb08c23f2c0593b727b002377cdfe 265 PIRSF PIRSF036628 1 265 7.3E-101 T 29-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CVS48_RS05205 2d8cb08c23f2c0593b727b002377cdfe 265 Gene3D G3DSA:2.60.120.10 120 265 6.4E-58 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS05205 2d8cb08c23f2c0593b727b002377cdfe 265 Pfam PF04962 KduI/IolB family 5 260 1.2E-103 T 29-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CVS48_RS05205 2d8cb08c23f2c0593b727b002377cdfe 265 SUPERFAMILY SSF51182 16 249 4.29E-62 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS05205 2d8cb08c23f2c0593b727b002377cdfe 265 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 16 260 2.0E-97 T 29-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CVS48_RS05205 2d8cb08c23f2c0593b727b002377cdfe 265 Gene3D G3DSA:2.60.120.10 14 119 1.2E-28 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS28345 ed30f0716b2ba9f5fdd1d262758b7598 200 PIRSF PIRSF006305 1 194 3.5E-47 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CVS48_RS28345 ed30f0716b2ba9f5fdd1d262758b7598 200 SUPERFAMILY SSF52972 5 187 2.09E-53 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CVS48_RS28345 ed30f0716b2ba9f5fdd1d262758b7598 200 TIGRFAM TIGR00172 maf: septum formation protein Maf 4 185 1.1E-39 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CVS48_RS28345 ed30f0716b2ba9f5fdd1d262758b7598 200 Gene3D G3DSA:3.90.950.10 3 192 9.1E-52 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CVS48_RS28345 ed30f0716b2ba9f5fdd1d262758b7598 200 Pfam PF02545 Maf-like protein 7 187 2.1E-40 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CVS48_RS28345 ed30f0716b2ba9f5fdd1d262758b7598 200 Hamap MF_00528 Septum formation protein Maf [maf]. 6 192 28.182 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 Gene3D G3DSA:1.10.275.10 1 136 9.0E-61 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 2.5E-33 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 2.5E-33 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 2.5E-33 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 2.5E-33 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 Gene3D G3DSA:1.20.200.10 137 413 2.1E-87 T 29-03-2018 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 Pfam PF00206 Lyase 11 341 2.1E-110 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 Gene3D G3DSA:1.10.40.30 414 461 4.1E-25 T 29-03-2018 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 Pfam PF10415 Fumarase C C-terminus 407 460 9.7E-25 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 SUPERFAMILY SSF48557 3 459 4.42E-153 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 459 4.1E-235 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 461 91.664 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 PRINTS PR00145 Argininosuccinate lyase family signature 132 154 3.1E-6 T 29-03-2018 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 3.1E-6 T 29-03-2018 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 3.1E-6 T 29-03-2018 CVS48_RS01790 8f8d1c14c089ed6347ee36bca4ff1d2b 464 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CVS48_RS25145 99d335a5e5f20e67a86dc4b7a0effe92 273 Pfam PF09339 IclR helix-turn-helix domain 5 53 1.6E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS25145 99d335a5e5f20e67a86dc4b7a0effe92 273 Gene3D G3DSA:1.10.10.10 1 71 8.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25145 99d335a5e5f20e67a86dc4b7a0effe92 273 SMART SM00346 2 92 1.2E-20 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS25145 99d335a5e5f20e67a86dc4b7a0effe92 273 SUPERFAMILY SSF46785 4 74 7.04E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25145 99d335a5e5f20e67a86dc4b7a0effe92 273 SUPERFAMILY SSF55781 73 247 1.24E-35 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS25145 99d335a5e5f20e67a86dc4b7a0effe92 273 Gene3D G3DSA:3.30.450.40 72 253 3.4E-35 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS25145 99d335a5e5f20e67a86dc4b7a0effe92 273 Pfam PF01614 Bacterial transcriptional regulator 122 246 2.0E-14 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS25580 903e56aedfbc2e6865427a9690e78b74 366 Gene3D G3DSA:3.40.50.10730 179 354 6.7E-28 T 29-03-2018 CVS48_RS25580 903e56aedfbc2e6865427a9690e78b74 366 SUPERFAMILY SSF51735 157 329 5.13E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25580 903e56aedfbc2e6865427a9690e78b74 366 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS25580 903e56aedfbc2e6865427a9690e78b74 366 Gene3D G3DSA:3.90.180.10 5 178 1.6E-39 T 29-03-2018 CVS48_RS25580 903e56aedfbc2e6865427a9690e78b74 366 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 149 1.3E-20 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS25580 903e56aedfbc2e6865427a9690e78b74 366 Pfam PF00107 Zinc-binding dehydrogenase 194 295 4.1E-27 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS25580 903e56aedfbc2e6865427a9690e78b74 366 SMART SM00829 12 359 2.5E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS25580 903e56aedfbc2e6865427a9690e78b74 366 SUPERFAMILY SSF50129 1 161 1.16E-38 T 29-03-2018 IPR011032 GroES-like CVS48_RS25580 903e56aedfbc2e6865427a9690e78b74 366 SUPERFAMILY SSF50129 334 361 1.16E-38 T 29-03-2018 IPR011032 GroES-like CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 SUPERFAMILY SSF47413 1 77 4.3E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 SUPERFAMILY SSF55234 80 147 4.18E-30 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 Hamap MF_00535 Cyanate hydratase [cynS]. 1 147 79.982 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 PRINTS PR01693 Cyanase signature 132 142 3.4E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 PRINTS PR01693 Cyanase signature 101 117 3.4E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 PRINTS PR01693 Cyanase signature 34 51 3.4E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 PRINTS PR01693 Cyanase signature 14 29 3.4E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 PRINTS PR01693 Cyanase signature 83 97 3.4E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 PIRSF PIRSF001263 1 147 1.8E-51 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 TIGRFAM TIGR00673 cynS: cyanase 6 147 7.0E-51 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 Gene3D G3DSA:3.30.1160.10 81 146 7.5E-37 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 Gene3D G3DSA:1.10.260.40 1 80 1.0E-8 T 29-03-2018 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 Pfam PF02560 Cyanate lyase C-terminal domain 79 145 9.7E-36 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25415 887503cf2dce0eaefb6ec71851df1b75 147 SMART SM01116 75 147 2.2E-49 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS17405 17c07888dff5238700b94c6ba354a8a9 178 PIRSF PIRSF000239 18 178 1.6E-22 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS17405 17c07888dff5238700b94c6ba354a8a9 178 Gene3D G3DSA:3.40.30.10 13 174 1.7E-31 T 29-03-2018 CVS48_RS17405 17c07888dff5238700b94c6ba354a8a9 178 SUPERFAMILY SSF52833 22 173 2.64E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS17405 17c07888dff5238700b94c6ba354a8a9 178 Pfam PF00578 AhpC/TSA family 25 153 1.8E-26 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 SUPERFAMILY SSF53671 89 399 1.7E-88 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 153 8.5E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 348 357 8.5E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 363 386 8.5E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 218 229 8.5E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 313 322 3.9E-29 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 217 234 3.9E-29 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 124 146 3.9E-29 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 163 172 3.9E-29 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 379 393 3.9E-29 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 90 398 2.3E-90 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 90 229 9.4E-42 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 242 396 6.0E-29 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 Gene3D G3DSA:3.40.50.1370 80 230 3.9E-49 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 Gene3D G3DSA:1.10.260.40 6 59 0.003 T 29-03-2018 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 Gene3D G3DSA:3.40.50.1370 231 400 5.1E-49 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26880 5f50edc6b483dd1b9c804854c8f825bd 430 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 134 141 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 Gene3D G3DSA:1.10.3860.10 1 411 6.6E-117 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 Pfam PF00375 Sodium:dicarboxylate symporter family 8 403 1.8E-109 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 6.9E-43 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 PRINTS PR00173 Glutamate-aspartate symporter signature 358 378 6.9E-43 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 6.9E-43 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 6.9E-43 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 PRINTS PR00173 Glutamate-aspartate symporter signature 331 350 6.9E-43 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 PRINTS PR00173 Glutamate-aspartate symporter signature 296 322 6.9E-43 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 6.9E-43 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 6.9E-43 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS13350 435b48b4664f5b0221e59e8494e1da46 436 SUPERFAMILY SSF118215 6 405 2.88E-113 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS25830 554217626fddfcdf97e313837addd81d 140 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 57 130 1.9E-19 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CVS48_RS25830 554217626fddfcdf97e313837addd81d 140 Gene3D G3DSA:3.10.50.30 51 140 1.1E-21 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CVS48_RS25830 554217626fddfcdf97e313837addd81d 140 SUPERFAMILY SSF54534 55 131 1.57E-16 T 29-03-2018 CVS48_RS25830 554217626fddfcdf97e313837addd81d 140 PIRSF PIRSF006092 28 132 1.1E-20 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CVS48_RS06530 b3330c3bab0b36db9cb2d9739ca9e3ff 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 60 1.0E-24 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06530 b3330c3bab0b36db9cb2d9739ca9e3ff 61 PIRSF PIRSF002211 1 61 4.1E-27 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06530 b3330c3bab0b36db9cb2d9739ca9e3ff 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 24 56 - T 29-03-2018 IPR018038 Ribosomal protein L30, conserved site CVS48_RS06530 b3330c3bab0b36db9cb2d9739ca9e3ff 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 60 20.263 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06530 b3330c3bab0b36db9cb2d9739ca9e3ff 61 SUPERFAMILY SSF55129 4 60 1.7E-20 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CVS48_RS06530 b3330c3bab0b36db9cb2d9739ca9e3ff 61 Pfam PF00327 Ribosomal protein L30p/L7e 6 56 2.6E-18 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CVS48_RS06530 b3330c3bab0b36db9cb2d9739ca9e3ff 61 Gene3D G3DSA:3.30.1390.20 6 60 8.3E-23 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CVS48_RS03560 7d9b3ba1b24eb76b52725cdfeab6976d 205 Gene3D G3DSA:3.40.50.300 1 204 1.4E-39 T 29-03-2018 CVS48_RS03560 7d9b3ba1b24eb76b52725cdfeab6976d 205 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 195 25.611 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CVS48_RS03560 7d9b3ba1b24eb76b52725cdfeab6976d 205 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 180 7.5E-43 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CVS48_RS03560 7d9b3ba1b24eb76b52725cdfeab6976d 205 SUPERFAMILY SSF52540 1 198 6.45E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03560 7d9b3ba1b24eb76b52725cdfeab6976d 205 Pfam PF01121 Dephospho-CoA kinase 4 180 9.4E-55 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 110.108 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 SMART SM00838 606 694 2.5E-56 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Gene3D G3DSA:3.30.230.10 499 614 1.4E-44 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Pfam PF14492 Elongation Factor G, domain II 409 483 2.2E-34 T 29-03-2018 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Pfam PF03764 Elongation factor G, domain IV 484 604 2.5E-48 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Gene3D G3DSA:3.30.70.870 405 498 5.9E-38 T 29-03-2018 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 3.9E-31 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Gene3D G3DSA:3.30.70.240 615 693 1.1E-32 T 29-03-2018 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Pfam PF03144 Elongation factor Tu domain 2 329 396 2.9E-19 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 SUPERFAMILY SSF54211 484 605 1.54E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 2.7E-65 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 SUPERFAMILY SSF54980 609 696 8.99E-30 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Gene3D G3DSA:3.40.50.300 1 293 3.4E-55 T 29-03-2018 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 SUPERFAMILY SSF54980 409 486 2.99E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 SUPERFAMILY SSF50447 271 407 6.63E-36 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Pfam PF00679 Elongation factor G C-terminus 606 693 1.1E-31 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 SMART SM00889 485 604 1.5E-75 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 Gene3D G3DSA:2.40.30.10 294 404 8.9E-30 T 29-03-2018 CVS48_RS06330 78aabfe4748ac537394801a65c6ebe8d 700 SUPERFAMILY SSF52540 6 288 1.32E-105 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS17620 ec9a50009ea9ce98098613f42e881a42 252 Gene3D G3DSA:3.20.20.70 52 251 1.3E-22 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS17620 ec9a50009ea9ce98098613f42e881a42 252 Pfam PF04055 Radical SAM superfamily 55 201 6.0E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS17620 ec9a50009ea9ce98098613f42e881a42 252 SUPERFAMILY SSF102114 52 239 7.98E-24 T 29-03-2018 CVS48_RS17620 ec9a50009ea9ce98098613f42e881a42 252 Pfam PF13353 4Fe-4S single cluster domain 50 124 1.6E-7 T 29-03-2018 CVS48_RS17620 ec9a50009ea9ce98098613f42e881a42 252 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 37 222 2.1E-54 T 29-03-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 SMART SM01274 19 152 2.8E-76 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 PIRSF PIRSF036684 1 764 0.0 T 29-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 SMART SM00919 164 401 3.2E-133 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 SUPERFAMILY SSF51735 164 439 3.81E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 Pfam PF01515 Phosphate acetyl/butaryl transferase 430 756 3.0E-95 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 Pfam PF00390 Malic enzyme, N-terminal domain 20 152 5.7E-26 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 SUPERFAMILY SSF53659 430 761 1.48E-88 T 29-03-2018 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 Gene3D G3DSA:3.40.718.10 452 754 1.9E-54 T 29-03-2018 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 SUPERFAMILY SSF53223 11 162 1.08E-50 T 29-03-2018 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 Pfam PF03949 Malic enzyme, NAD binding domain 166 361 1.4E-20 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 Gene3D G3DSA:3.40.50.10380 6 161 3.7E-34 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CVS48_RS12390 59ad618574e9e92d4c988669e80192b3 765 Gene3D G3DSA:3.40.50.720 162 451 7.9E-82 T 29-03-2018 CVS48_RS19910 dba411b8534d25fb452acca402571006 93 PIRSF PIRSF028784 1 93 7.4E-29 T 29-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CVS48_RS19910 dba411b8534d25fb452acca402571006 93 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 34 85 5.3E-21 T 29-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CVS48_RS19805 002a654bcee43ccd4e1192a4838bc66a 259 SUPERFAMILY SSF53098 4 226 5.69E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS19805 002a654bcee43ccd4e1192a4838bc66a 259 Gene3D G3DSA:3.30.420.10 4 219 3.9E-36 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS19805 002a654bcee43ccd4e1192a4838bc66a 259 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 47 256 6.6E-90 T 29-03-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like CVS48_RS16090 d55acbdea420659d385e8432ce9c39a2 683 Gene3D G3DSA:3.30.1490.20 363 547 6.6E-38 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS16090 d55acbdea420659d385e8432ce9c39a2 683 Gene3D G3DSA:3.50.30.10 232 343 5.4E-6 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CVS48_RS16090 d55acbdea420659d385e8432ce9c39a2 683 Gene3D G3DSA:3.30.470.20 548 679 5.6E-22 T 29-03-2018 CVS48_RS16090 d55acbdea420659d385e8432ce9c39a2 683 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 381 678 1.4E-45 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CVS48_RS16090 d55acbdea420659d385e8432ce9c39a2 683 SUPERFAMILY SSF56059 369 678 5.77E-48 T 29-03-2018 CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 SUPERFAMILY SSF52540 1334 1646 8.64E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 SUPERFAMILY SSF52540 694 769 8.64E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 Gene3D G3DSA:3.40.960.10 1665 1787 3.0E-28 T 29-03-2018 CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 Pfam PF11784 Protein of unknown function (DUF3320) 1862 1910 1.4E-14 T 29-03-2018 IPR021754 Protein of unknown function DUF3320 CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 SUPERFAMILY SSF52980 1662 1771 8.04E-16 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 Pfam PF13086 AAA domain 1360 1402 1.4E-6 T 29-03-2018 CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 Pfam PF13087 AAA domain 1438 1617 1.4E-13 T 29-03-2018 CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 Gene3D G3DSA:3.40.50.300 1451 1639 1.5E-16 T 29-03-2018 CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 Gene3D G3DSA:3.40.50.300 703 1450 3.3E-42 T 29-03-2018 CVS48_RS28945 a834df83b40b17a768d710a02e6d4ca4 2029 Pfam PF13195 Protein of unknown function (DUF4011) 417 590 8.6E-41 T 29-03-2018 IPR025103 Protein of unknown function DUF4011 CVS48_RS28585 d01f75e3941e3e38ad3c5c035b2bf8c5 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 238 2.7E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS28585 d01f75e3941e3e38ad3c5c035b2bf8c5 244 SUPERFAMILY SSF52172 6 131 1.11E-42 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS28585 d01f75e3941e3e38ad3c5c035b2bf8c5 244 SMART SM00448 10 121 4.6E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS28585 d01f75e3941e3e38ad3c5c035b2bf8c5 244 SMART SM00862 162 238 1.7E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS28585 d01f75e3941e3e38ad3c5c035b2bf8c5 244 SUPERFAMILY SSF46894 138 240 6.8E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS28585 d01f75e3941e3e38ad3c5c035b2bf8c5 244 Gene3D G3DSA:3.40.50.2300 1 135 1.9E-39 T 29-03-2018 CVS48_RS28585 d01f75e3941e3e38ad3c5c035b2bf8c5 244 Pfam PF00072 Response regulator receiver domain 12 122 7.8E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS28585 d01f75e3941e3e38ad3c5c035b2bf8c5 244 Gene3D G3DSA:1.10.10.10 136 243 2.1E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 SUPERFAMILY SSF63411 739 914 5.42E-30 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 74 97 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 Gene3D G3DSA:3.30.830.10 29 247 1.2E-56 T 29-03-2018 CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 SUPERFAMILY SSF63411 478 719 7.17E-26 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 Gene3D G3DSA:3.30.830.10 477 718 1.7E-24 T 29-03-2018 CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 Pfam PF00675 Insulinase (Peptidase family M16) 53 199 1.7E-21 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 SUPERFAMILY SSF63411 42 258 1.58E-52 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 Gene3D G3DSA:3.30.830.10 733 918 2.0E-32 T 29-03-2018 CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 Pfam PF05193 Peptidase M16 inactive domain 666 845 1.4E-26 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 Pfam PF05193 Peptidase M16 inactive domain 208 382 3.8E-27 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 Gene3D G3DSA:3.30.830.10 248 444 9.4E-26 T 29-03-2018 CVS48_RS00395 49ee1dda5cfd712a15fad5a137ad2255 918 SUPERFAMILY SSF63411 264 450 2.87E-25 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 3.0E-76 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 3.0E-76 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 3.0E-76 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 3.0E-76 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 3.0E-76 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 3.0E-76 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.0E-76 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 3.0E-76 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.0E-76 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 SUPERFAMILY SSF82693 40 134 5.49E-23 T 29-03-2018 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 Gene3D G3DSA:3.30.70.1430 40 143 1.4E-24 T 29-03-2018 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 SUPERFAMILY SSF82693 556 653 1.67E-13 T 29-03-2018 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 Pfam PF00873 AcrB/AcrD/AcrF family 4 1014 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 SUPERFAMILY SSF82714 183 266 4.58E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 SUPERFAMILY SSF82866 290 491 4.32E-47 T 29-03-2018 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 Gene3D G3DSA:3.30.70.1430 558 657 1.9E-9 T 29-03-2018 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 Gene3D G3DSA:3.30.2090.10 181 269 4.2E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 Gene3D G3DSA:3.30.2090.10 708 796 2.1E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 Gene3D G3DSA:1.20.1640.10 807 1026 3.3E-34 T 29-03-2018 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 Gene3D G3DSA:1.20.1640.10 281 503 1.0E-47 T 29-03-2018 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 SUPERFAMILY SSF82866 798 1017 1.09E-44 T 29-03-2018 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 SUPERFAMILY SSF82714 708 793 1.19E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 SUPERFAMILY SSF82693 138 182 3.84E-23 T 29-03-2018 CVS48_RS03545 ac2ea3a2855112750c7005d745bf46db 1033 SUPERFAMILY SSF82693 268 324 3.84E-23 T 29-03-2018 CVS48_RS23700 8baafd3f637f0f7dd1e90ede8f4baaba 420 PIRSF PIRSF000521 121 420 2.2E-43 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS23700 8baafd3f637f0f7dd1e90ede8f4baaba 420 PIRSF PIRSF000521 3 128 2.7E-4 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS23700 8baafd3f637f0f7dd1e90ede8f4baaba 420 SUPERFAMILY SSF53383 23 418 2.26E-129 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS23700 8baafd3f637f0f7dd1e90ede8f4baaba 420 Gene3D G3DSA:3.40.640.10 178 305 2.5E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS23700 8baafd3f637f0f7dd1e90ede8f4baaba 420 Gene3D G3DSA:3.90.1150.10 306 420 4.9E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS23700 8baafd3f637f0f7dd1e90ede8f4baaba 420 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 419 1.5E-180 T 29-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CVS48_RS23700 8baafd3f637f0f7dd1e90ede8f4baaba 420 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS23700 8baafd3f637f0f7dd1e90ede8f4baaba 420 Gene3D G3DSA:3.90.1150.10 20 177 1.5E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS23700 8baafd3f637f0f7dd1e90ede8f4baaba 420 Pfam PF00202 Aminotransferase class-III 24 418 8.6E-124 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS01300 19174a0b59f4a0af303833fd576422fb 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 322 5.6E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01300 19174a0b59f4a0af303833fd576422fb 325 Gene3D G3DSA:3.40.190.10 152 297 4.3E-9 T 29-03-2018 CVS48_RS01300 19174a0b59f4a0af303833fd576422fb 325 SUPERFAMILY SSF53850 113 287 3.26E-12 T 29-03-2018 CVS48_RS01300 19174a0b59f4a0af303833fd576422fb 325 PIRSF PIRSF017082 1 325 1.0E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04035 24074b33d3f40e2332ba4b6d92250bce 376 Pfam PF07687 Peptidase dimerisation domain 178 273 8.7E-18 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS04035 24074b33d3f40e2332ba4b6d92250bce 376 Gene3D G3DSA:3.40.630.10 2 376 7.5E-54 T 29-03-2018 CVS48_RS04035 24074b33d3f40e2332ba4b6d92250bce 376 Pfam PF01546 Peptidase family M20/M25/M40 77 373 1.4E-28 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS04035 24074b33d3f40e2332ba4b6d92250bce 376 PIRSF PIRSF037238 1 376 1.6E-139 T 29-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase CVS48_RS04035 24074b33d3f40e2332ba4b6d92250bce 376 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 75 84 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CVS48_RS04035 24074b33d3f40e2332ba4b6d92250bce 376 SUPERFAMILY SSF55031 181 290 2.84E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS04035 24074b33d3f40e2332ba4b6d92250bce 376 SUPERFAMILY SSF53187 300 376 1.79E-49 T 29-03-2018 CVS48_RS04035 24074b33d3f40e2332ba4b6d92250bce 376 SUPERFAMILY SSF53187 6 190 1.79E-49 T 29-03-2018 CVS48_RS27910 ef2e7c2450f14a66b89378eab8f75e9a 138 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 23 132 2.2E-32 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27910 ef2e7c2450f14a66b89378eab8f75e9a 138 PIRSF PIRSF000178 20 135 2.3E-23 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27910 ef2e7c2450f14a66b89378eab8f75e9a 138 SUPERFAMILY SSF81343 7 134 6.76E-25 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27910 ef2e7c2450f14a66b89378eab8f75e9a 138 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 21 130 3.2E-25 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27910 ef2e7c2450f14a66b89378eab8f75e9a 138 Gene3D G3DSA:1.20.1300.10 28 137 5.5E-21 T 29-03-2018 CVS48_RS09025 a3d50ef48e6e93b3292d71c8fb136ac5 840 Gene3D G3DSA:2.30.30.60 655 704 2.6E-13 T 29-03-2018 CVS48_RS09025 a3d50ef48e6e93b3292d71c8fb136ac5 840 SUPERFAMILY SSF82861 553 636 6.93E-11 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CVS48_RS09025 a3d50ef48e6e93b3292d71c8fb136ac5 840 Gene3D G3DSA:3.30.70.100 705 799 3.2E-24 T 29-03-2018 CVS48_RS09025 a3d50ef48e6e93b3292d71c8fb136ac5 840 Pfam PF00924 Mechanosensitive ion channel 596 794 2.5E-53 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CVS48_RS09025 a3d50ef48e6e93b3292d71c8fb136ac5 840 SUPERFAMILY SSF50182 638 703 6.54E-17 T 29-03-2018 IPR010920 LSM domain CVS48_RS09025 a3d50ef48e6e93b3292d71c8fb136ac5 840 SUPERFAMILY SSF82689 707 804 3.53E-28 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 Gene3D G3DSA:2.30.42.10 287 390 1.1E-25 T 29-03-2018 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 Pfam PF13180 PDZ domain 289 377 3.2E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 Pfam PF13180 PDZ domain 423 485 1.1E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 43 483 2.2E-143 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 SUPERFAMILY SSF50156 401 485 6.44E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 Gene3D G3DSA:2.40.10.10 39 186 7.6E-37 T 29-03-2018 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 SMART SM00228 286 368 3.5E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 SMART SM00228 400 478 0.0016 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 Gene3D G3DSA:2.30.42.10 398 489 8.2E-14 T 29-03-2018 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 Gene3D G3DSA:2.40.10.10 187 286 2.4E-37 T 29-03-2018 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 SUPERFAMILY SSF50494 41 277 1.42E-65 T 29-03-2018 IPR009003 Peptidase S1, PA clan CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 Pfam PF13365 Trypsin-like peptidase domain 116 247 4.3E-33 T 29-03-2018 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 PRINTS PR00834 HtrA/DegQ protease family signature 125 137 6.5E-53 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 PRINTS PR00834 HtrA/DegQ protease family signature 186 210 6.5E-53 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 PRINTS PR00834 HtrA/DegQ protease family signature 146 166 6.5E-53 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 PRINTS PR00834 HtrA/DegQ protease family signature 326 338 6.5E-53 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 6.5E-53 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 PRINTS PR00834 HtrA/DegQ protease family signature 218 235 6.5E-53 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS28280 e857fef0f1c785429c8c2f4f6c443d38 489 SUPERFAMILY SSF50156 244 369 2.23E-22 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS13215 8b17c67ad94bdea0b13cb5dc02c386b5 226 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 33 177 2.4E-35 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS13215 8b17c67ad94bdea0b13cb5dc02c386b5 226 Pfam PF00994 Probable molybdopterin binding domain 35 178 1.4E-28 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS13215 8b17c67ad94bdea0b13cb5dc02c386b5 226 SMART SM00852 34 184 8.8E-25 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS13215 8b17c67ad94bdea0b13cb5dc02c386b5 226 Gene3D G3DSA:3.40.980.10 27 219 9.9E-40 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS13215 8b17c67ad94bdea0b13cb5dc02c386b5 226 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 96 109 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CVS48_RS13215 8b17c67ad94bdea0b13cb5dc02c386b5 226 SUPERFAMILY SSF53218 32 219 4.71E-45 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS13745 a3eb38f57b8e1443dfc5980198b8041a 346 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 19 0.001 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CVS48_RS13745 a3eb38f57b8e1443dfc5980198b8041a 346 Pfam PF13379 NMT1-like family 33 271 1.1E-27 T 29-03-2018 CVS48_RS13745 a3eb38f57b8e1443dfc5980198b8041a 346 Gene3D G3DSA:3.40.190.10 138 340 5.4E-33 T 29-03-2018 CVS48_RS13745 a3eb38f57b8e1443dfc5980198b8041a 346 Gene3D G3DSA:3.40.190.10 30 137 2.6E-13 T 29-03-2018 CVS48_RS13745 a3eb38f57b8e1443dfc5980198b8041a 346 SUPERFAMILY SSF53850 33 282 2.32E-43 T 29-03-2018 CVS48_RS18845 99d6f1d5cf8ffb7aa491755f64a32e44 241 Pfam PF01479 S4 domain 6 51 4.2E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS18845 99d6f1d5cf8ffb7aa491755f64a32e44 241 SMART SM00363 5 60 1.8E-4 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS18845 99d6f1d5cf8ffb7aa491755f64a32e44 241 Gene3D G3DSA:3.30.70.580 61 159 6.1E-11 T 29-03-2018 CVS48_RS18845 99d6f1d5cf8ffb7aa491755f64a32e44 241 Gene3D G3DSA:3.10.290.10 1 60 4.1E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS18845 99d6f1d5cf8ffb7aa491755f64a32e44 241 SUPERFAMILY SSF55120 66 239 5.4E-18 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS18845 99d6f1d5cf8ffb7aa491755f64a32e44 241 SUPERFAMILY SSF55174 6 92 9.55E-12 T 29-03-2018 CVS48_RS18845 99d6f1d5cf8ffb7aa491755f64a32e44 241 Gene3D G3DSA:3.30.70.1560 160 218 1.3E-12 T 29-03-2018 CVS48_RS21780 c93be7f1145a55ab305c87a0ceb9e8f7 728 SUPERFAMILY SSF56935 563 728 2.52E-124 T 29-03-2018 CVS48_RS21780 c93be7f1145a55ab305c87a0ceb9e8f7 728 SUPERFAMILY SSF56935 33 528 2.52E-124 T 29-03-2018 CVS48_RS21780 c93be7f1145a55ab305c87a0ceb9e8f7 728 Gene3D G3DSA:2.170.130.10 26 166 1.3E-38 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS21780 c93be7f1145a55ab305c87a0ceb9e8f7 728 Pfam PF00593 TonB dependent receptor 269 727 2.8E-53 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS21780 c93be7f1145a55ab305c87a0ceb9e8f7 728 Gene3D G3DSA:2.40.170.20 170 728 9.5E-81 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS21780 c93be7f1145a55ab305c87a0ceb9e8f7 728 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 159 1.3E-30 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS21780 c93be7f1145a55ab305c87a0ceb9e8f7 728 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 40 - T 29-03-2018 IPR010916 TonB box, conserved site CVS48_RS11315 cc420c42924092863b945fe9a13f49c7 316 Pfam PF03466 LysR substrate binding domain 93 298 2.1E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS11315 cc420c42924092863b945fe9a13f49c7 316 Gene3D G3DSA:1.10.10.10 1 88 5.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11315 cc420c42924092863b945fe9a13f49c7 316 Gene3D G3DSA:3.40.190.10 179 268 2.0E-18 T 29-03-2018 CVS48_RS11315 cc420c42924092863b945fe9a13f49c7 316 SUPERFAMILY SSF53850 94 305 5.79E-35 T 29-03-2018 CVS48_RS11315 cc420c42924092863b945fe9a13f49c7 316 SUPERFAMILY SSF46785 3 87 5.44E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11315 cc420c42924092863b945fe9a13f49c7 316 Gene3D G3DSA:3.40.190.10 92 178 9.3E-12 T 29-03-2018 CVS48_RS11315 cc420c42924092863b945fe9a13f49c7 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 3.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 344 2.2E-56 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 Gene3D G3DSA:3.50.50.60 524 687 4.6E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 391 633 2.6E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 SUPERFAMILY SSF51905 366 684 3.11E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 608 622 2.4E-6 T 29-03-2018 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 391 413 2.4E-6 T 29-03-2018 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 661 668 2.4E-6 T 29-03-2018 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 607 623 3.5E-5 T 29-03-2018 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 392 411 3.5E-5 T 29-03-2018 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 SUPERFAMILY SSF51395 1 374 8.93E-99 T 29-03-2018 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 Gene3D G3DSA:3.20.20.70 1 384 1.0E-102 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS01160 1c6c5d233570768578b96e90023cdafe 687 Gene3D G3DSA:3.40.50.720 385 503 1.2E-18 T 29-03-2018 CVS48_RS18295 88ac5954cb29eec11d1071323810d96e 252 SMART SM00419 173 220 2.4E-4 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS18295 88ac5954cb29eec11d1071323810d96e 252 Gene3D G3DSA:1.10.10.10 170 247 2.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18295 88ac5954cb29eec11d1071323810d96e 252 SUPERFAMILY SSF51206 19 148 6.36E-12 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CVS48_RS18295 88ac5954cb29eec11d1071323810d96e 252 Gene3D G3DSA:2.60.120.10 16 169 1.6E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS18295 88ac5954cb29eec11d1071323810d96e 252 SUPERFAMILY SSF46785 157 232 8.95E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18295 88ac5954cb29eec11d1071323810d96e 252 Pfam PF13545 Crp-like helix-turn-helix domain 160 226 3.9E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS18295 88ac5954cb29eec11d1071323810d96e 252 SMART SM00100 22 143 1.8E-4 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS08800 b45e2313a762a07b9b7108da86e1a418 261 PIRSF PIRSF006241 1 261 1.3E-95 T 29-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 CVS48_RS08800 b45e2313a762a07b9b7108da86e1a418 261 Pfam PF01261 Xylose isomerase-like TIM barrel 21 218 6.0E-32 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CVS48_RS08800 b45e2313a762a07b9b7108da86e1a418 261 Gene3D G3DSA:3.20.20.150 1 260 4.3E-56 T 29-03-2018 CVS48_RS08800 b45e2313a762a07b9b7108da86e1a418 261 SUPERFAMILY SSF51658 1 258 7.05E-83 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.773 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 Gene3D G3DSA:3.40.50.300 83 375 8.5E-117 T 29-03-2018 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 PIRSF PIRSF039088 1 513 7.5E-239 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 SUPERFAMILY SSF47917 383 510 2.17E-45 T 29-03-2018 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 510 1.2E-249 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 SUPERFAMILY SSF50615 10 94 1.29E-28 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 2.9E-74 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 SUPERFAMILY SSF52540 96 381 3.44E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 6.1E-17 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 4.8E-46 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 Gene3D G3DSA:1.20.150.20 384 510 6.9E-47 T 29-03-2018 CVS48_RS04100 3573b6ead6a15d4eb35b0cc8ca85027a 513 Gene3D G3DSA:2.40.30.20 3 82 8.9E-34 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS14870 b0344dae1e6c4993dfb597aeb18238f7 437 Gene3D G3DSA:1.10.10.10 292 366 1.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14870 b0344dae1e6c4993dfb597aeb18238f7 437 Pfam PF03631 Virulence factor BrkB 41 285 5.4E-57 T 29-03-2018 IPR017039 Virulence factor BrkB CVS48_RS14870 b0344dae1e6c4993dfb597aeb18238f7 437 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 31 318 22.85 T 29-03-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial CVS48_RS14870 b0344dae1e6c4993dfb597aeb18238f7 437 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 34 286 5.1E-72 T 29-03-2018 IPR017039 Virulence factor BrkB CVS48_RS16830 3f9092d39f722500eacf9595dba3e98c 384 Gene3D G3DSA:3.40.1690.10 218 353 3.6E-60 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CVS48_RS16830 3f9092d39f722500eacf9595dba3e98c 384 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 8 354 4.7E-125 T 29-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 CVS48_RS16830 3f9092d39f722500eacf9595dba3e98c 384 SUPERFAMILY SSF160544 244 351 2.35E-42 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CVS48_RS16830 3f9092d39f722500eacf9595dba3e98c 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 3.8E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CVS48_RS16830 3f9092d39f722500eacf9595dba3e98c 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 3.8E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CVS48_RS16830 3f9092d39f722500eacf9595dba3e98c 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 3.8E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CVS48_RS16830 3f9092d39f722500eacf9595dba3e98c 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 3.8E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CVS48_RS16830 3f9092d39f722500eacf9595dba3e98c 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 3.8E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CVS48_RS16830 3f9092d39f722500eacf9595dba3e98c 384 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 347 4.1E-126 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CVS48_RS20030 49eb414fb742bf451614a6c5f642a5a3 361 SMART SM00382 27 207 1.7E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS20030 49eb414fb742bf451614a6c5f642a5a3 361 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS20030 49eb414fb742bf451614a6c5f642a5a3 361 Gene3D G3DSA:3.40.50.300 2 231 7.9E-53 T 29-03-2018 CVS48_RS20030 49eb414fb742bf451614a6c5f642a5a3 361 Pfam PF08402 TOBE domain 271 341 2.8E-6 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS20030 49eb414fb742bf451614a6c5f642a5a3 361 SUPERFAMILY SSF52540 9 239 5.93E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20030 49eb414fb742bf451614a6c5f642a5a3 361 SUPERFAMILY SSF50331 234 346 7.65E-19 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS20030 49eb414fb742bf451614a6c5f642a5a3 361 Pfam PF00005 ABC transporter 20 158 1.7E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS20030 49eb414fb742bf451614a6c5f642a5a3 361 Gene3D G3DSA:2.40.50.140 232 334 3.2E-10 T 29-03-2018 CVS48_RS03310 f3b9a0d20882de3abf040ceb237f8fcd 441 SUPERFAMILY SSF51556 59 366 5.96E-63 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS03310 f3b9a0d20882de3abf040ceb237f8fcd 441 Gene3D G3DSA:3.20.20.140 73 361 4.4E-52 T 29-03-2018 CVS48_RS03310 f3b9a0d20882de3abf040ceb237f8fcd 441 SUPERFAMILY SSF51338 1 58 8.64E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS03310 f3b9a0d20882de3abf040ceb237f8fcd 441 SUPERFAMILY SSF51338 382 438 8.64E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS03310 f3b9a0d20882de3abf040ceb237f8fcd 441 Gene3D G3DSA:2.30.40.10 2 72 3.0E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS03310 f3b9a0d20882de3abf040ceb237f8fcd 441 Gene3D G3DSA:2.30.40.10 362 441 2.8E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS12325 145d9ebf49fd8be9258fc94be0558003 189 SUPERFAMILY SSF51182 66 187 3.3E-15 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS12325 145d9ebf49fd8be9258fc94be0558003 189 SMART SM00530 17 72 1.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS12325 145d9ebf49fd8be9258fc94be0558003 189 Gene3D G3DSA:1.10.260.40 1 77 1.1E-18 T 29-03-2018 CVS48_RS12325 145d9ebf49fd8be9258fc94be0558003 189 Pfam PF13560 Helix-turn-helix domain 13 68 6.3E-15 T 29-03-2018 CVS48_RS12325 145d9ebf49fd8be9258fc94be0558003 189 SUPERFAMILY SSF47413 10 79 1.91E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS12325 145d9ebf49fd8be9258fc94be0558003 189 Gene3D G3DSA:2.60.120.10 78 184 2.7E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 Gene3D G3DSA:1.10.10.10 5 91 1.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 Pfam PF03466 LysR substrate binding domain 90 295 2.9E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 SUPERFAMILY SSF46785 5 90 1.36E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 Gene3D G3DSA:3.40.190.10 180 268 1.3E-29 T 29-03-2018 CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 SUPERFAMILY SSF53850 91 297 1.52E-43 T 29-03-2018 CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 5.2E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 Gene3D G3DSA:3.40.190.10 92 179 5.0E-12 T 29-03-2018 CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17485 be58c06b27786b5ea129b6e4bc101b85 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 5 669 27.057 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 SUPERFAMILY SSF55874 5 203 5.76E-51 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 SUPERFAMILY SSF54211 196 326 6.45E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 Gene3D G3DSA:3.30.565.10 1 197 1.4E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 7 306 3.0E-87 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 97 103 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 Gene3D G3DSA:3.30.230.10 198 325 1.2E-28 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 SMART SM01340 208 326 6.8E-55 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 SUPERFAMILY SSF118116 481 671 4.18E-57 T 29-03-2018 CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 Pfam PF08676 MutL C terminal dimerisation domain 482 629 4.2E-47 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 129 4.6E-10 T 29-03-2018 CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 208 325 9.5E-37 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CVS48_RS01810 3ac87563a230a427ed0473486eaccba7 673 SMART SM00853 486 629 2.4E-52 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CVS48_RS22260 31d2d69cd88bbd6770dc2099a12b1185 398 Gene3D G3DSA:3.40.50.1950 1 181 7.2E-59 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CVS48_RS22260 31d2d69cd88bbd6770dc2099a12b1185 398 SUPERFAMILY SSF102645 184 396 2.75E-67 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CVS48_RS22260 31d2d69cd88bbd6770dc2099a12b1185 398 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 367 5.9E-61 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CVS48_RS22260 31d2d69cd88bbd6770dc2099a12b1185 398 SUPERFAMILY SSF52507 3 181 1.31E-60 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CVS48_RS22260 31d2d69cd88bbd6770dc2099a12b1185 398 Pfam PF02441 Flavoprotein 7 178 2.7E-44 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CVS48_RS22260 31d2d69cd88bbd6770dc2099a12b1185 398 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 392 9.0E-125 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CVS48_RS22260 31d2d69cd88bbd6770dc2099a12b1185 398 Gene3D G3DSA:3.40.50.10300 182 398 1.3E-59 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 183 205 2.0E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 216 231 2.0E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 284 292 2.0E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 Gene3D G3DSA:2.60.120.10 19 149 1.0E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 SMART SM00100 22 140 1.3E-12 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 SUPERFAMILY SSF51905 182 371 8.48E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 184 203 1.4E-5 T 29-03-2018 CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 301 1.4E-5 T 29-03-2018 CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 SUPERFAMILY SSF51206 23 147 8.77E-22 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 183 291 1.3E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 Gene3D G3DSA:3.50.50.60 182 374 1.5E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18160 675de40e7368feca5152d9a5b0daceee 376 Pfam PF00027 Cyclic nucleotide-binding domain 41 125 4.4E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS28335 f815a636921d0061ded908fcdcfcd9e1 60 SUPERFAMILY SSF57829 2 55 1.53E-17 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CVS48_RS28335 f815a636921d0061ded908fcdcfcd9e1 60 Pfam PF01783 Ribosomal L32p protein family 2 55 6.9E-19 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS28335 f815a636921d0061ded908fcdcfcd9e1 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.8E-20 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS28335 f815a636921d0061ded908fcdcfcd9e1 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 16.956 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS00980 57be083dfb201f0bd2b803be66ac31c7 70 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 12 62 3.2E-25 T 29-03-2018 IPR010260 DNA-binding transcriptional activator AlpA CVS48_RS22360 134a4d2ab23b75bd9aac5d9dbcd2e31f 267 SUPERFAMILY SSF52540 4 251 2.07E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22360 134a4d2ab23b75bd9aac5d9dbcd2e31f 267 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 251 1.1E-10 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS22360 134a4d2ab23b75bd9aac5d9dbcd2e31f 267 Pfam PF00005 ABC transporter 20 180 1.3E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22360 134a4d2ab23b75bd9aac5d9dbcd2e31f 267 SMART SM00382 29 237 7.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22360 134a4d2ab23b75bd9aac5d9dbcd2e31f 267 Gene3D G3DSA:3.40.50.300 1 266 1.3E-59 T 29-03-2018 CVS48_RS07735 a9e9dcf42aca2fbe84fd6fff010c8866 479 Gene3D G3DSA:3.40.640.10 122 345 6.8E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS07735 a9e9dcf42aca2fbe84fd6fff010c8866 479 SMART SM00345 7 66 7.1E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS07735 a9e9dcf42aca2fbe84fd6fff010c8866 479 SUPERFAMILY SSF46785 2 75 8.68E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07735 a9e9dcf42aca2fbe84fd6fff010c8866 479 Pfam PF00155 Aminotransferase class I and II 148 449 3.3E-33 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS07735 a9e9dcf42aca2fbe84fd6fff010c8866 479 Gene3D G3DSA:1.10.10.10 1 68 6.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07735 a9e9dcf42aca2fbe84fd6fff010c8866 479 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 3.1E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS07735 a9e9dcf42aca2fbe84fd6fff010c8866 479 Gene3D G3DSA:3.90.1150.10 346 476 2.0E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS07735 a9e9dcf42aca2fbe84fd6fff010c8866 479 SUPERFAMILY SSF53383 96 468 2.39E-96 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 Gene3D G3DSA:3.40.190.10 181 268 4.9E-16 T 29-03-2018 CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.4E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 Pfam PF03466 LysR substrate binding domain 88 291 1.5E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 Gene3D G3DSA:3.40.190.10 91 180 7.0E-17 T 29-03-2018 CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 SUPERFAMILY SSF53850 88 296 2.27E-37 T 29-03-2018 CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 SUPERFAMILY SSF46785 6 111 2.68E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20900 705c95dbdff76f3ada4950e147058630 307 Gene3D G3DSA:1.10.10.10 2 84 4.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07790 b5853cb14496fcacb634ac22dbf384b2 524 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 503 4.3E-176 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CVS48_RS07790 b5853cb14496fcacb634ac22dbf384b2 524 PIRSF PIRSF006446 2 325 4.2E-113 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CVS48_RS07790 b5853cb14496fcacb634ac22dbf384b2 524 PIRSF PIRSF006446 335 523 2.2E-38 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 Gene3D G3DSA:1.10.10.10 1 89 3.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 Gene3D G3DSA:3.40.190.10 176 255 4.1E-11 T 29-03-2018 CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 Pfam PF03466 LysR substrate binding domain 88 281 1.2E-25 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 SUPERFAMILY SSF46785 4 111 1.59E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.0E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 Gene3D G3DSA:3.40.190.10 92 175 1.5E-14 T 29-03-2018 CVS48_RS06180 eb2385c9ef3dd598924317f878a60d4a 297 SUPERFAMILY SSF53850 89 282 4.21E-28 T 29-03-2018 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 Pfam PF09334 tRNA synthetases class I (M) 44 177 1.5E-17 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 SUPERFAMILY SSF50677 233 432 8.79E-51 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 26 884 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 Gene3D G3DSA:1.10.730.10 629 885 1.4E-50 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 Pfam PF08264 Anticodon-binding domain of tRNA 724 846 2.7E-14 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 4.0E-48 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 4.0E-48 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 576 586 4.0E-48 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 159 175 4.0E-48 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 505 523 4.0E-48 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 543 565 4.0E-48 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 222 241 4.0E-48 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 SUPERFAMILY SSF47323 682 884 6.17E-30 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 Gene3D G3DSA:3.90.740.10 237 469 1.5E-55 T 29-03-2018 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 228 418 6.5E-66 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 Gene3D G3DSA:3.40.50.620 1 236 3.8E-66 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 435 590 1.4E-8 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 SUPERFAMILY SSF52374 434 687 4.61E-142 T 29-03-2018 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 SUPERFAMILY SSF52374 8 233 4.61E-142 T 29-03-2018 CVS48_RS25995 696d4adeb2f1135cb315e6829398ef9c 885 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 885 22.256 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CVS48_RS27190 f23c27b6e427cf36d86cb980325fb196 301 SUPERFAMILY SSF53850 89 296 4.16E-43 T 29-03-2018 CVS48_RS27190 f23c27b6e427cf36d86cb980325fb196 301 Pfam PF03466 LysR substrate binding domain 89 291 4.2E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS27190 f23c27b6e427cf36d86cb980325fb196 301 Gene3D G3DSA:1.10.10.10 3 84 4.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27190 f23c27b6e427cf36d86cb980325fb196 301 Gene3D G3DSA:3.40.190.10 176 262 2.4E-24 T 29-03-2018 CVS48_RS27190 f23c27b6e427cf36d86cb980325fb196 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 9.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS27190 f23c27b6e427cf36d86cb980325fb196 301 SUPERFAMILY SSF46785 3 111 1.72E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27190 f23c27b6e427cf36d86cb980325fb196 301 Gene3D G3DSA:3.40.190.10 89 175 9.5E-12 T 29-03-2018 CVS48_RS25320 157254b0599f4c1031e400ffe2cf9b21 264 SMART SM00062 37 258 1.5E-37 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS25320 157254b0599f4c1031e400ffe2cf9b21 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 255 2.2E-37 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS25320 157254b0599f4c1031e400ffe2cf9b21 264 Gene3D G3DSA:3.40.190.10 27 135 5.3E-30 T 29-03-2018 CVS48_RS25320 157254b0599f4c1031e400ffe2cf9b21 264 Gene3D G3DSA:3.40.190.10 136 217 2.3E-13 T 29-03-2018 CVS48_RS25320 157254b0599f4c1031e400ffe2cf9b21 264 SUPERFAMILY SSF53850 38 258 1.34E-48 T 29-03-2018 CVS48_RS10095 f717c5b3989432b19c04aa3a59f1aae2 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 317 1.8E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS10095 f717c5b3989432b19c04aa3a59f1aae2 321 SUPERFAMILY SSF53850 108 282 1.03E-16 T 29-03-2018 CVS48_RS10095 f717c5b3989432b19c04aa3a59f1aae2 321 PIRSF PIRSF017082 1 321 3.8E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS10095 f717c5b3989432b19c04aa3a59f1aae2 321 Gene3D G3DSA:3.40.190.10 131 290 2.5E-14 T 29-03-2018 CVS48_RS23705 ac4e2c61d84c06e347e5914a7f10a396 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS23705 ac4e2c61d84c06e347e5914a7f10a396 489 SUPERFAMILY SSF53720 13 486 8.12E-172 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS23705 ac4e2c61d84c06e347e5914a7f10a396 489 Pfam PF00171 Aldehyde dehydrogenase family 24 482 2.1E-172 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS23705 ac4e2c61d84c06e347e5914a7f10a396 489 Gene3D G3DSA:3.40.605.10 6 274 1.6E-102 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS23705 ac4e2c61d84c06e347e5914a7f10a396 489 Gene3D G3DSA:3.40.309.10 275 453 1.8E-74 T 29-03-2018 CVS48_RS23705 ac4e2c61d84c06e347e5914a7f10a396 489 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 35 481 2.5E-221 T 29-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 CVS48_RS23705 ac4e2c61d84c06e347e5914a7f10a396 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 287 298 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS12745 c3d5cce0e1c596a83c9009bd177d1548 104 Pfam PF13670 Peptidase propeptide and YPEB domain 22 100 1.8E-14 T 29-03-2018 IPR025711 PepSY domain CVS48_RS12745 c3d5cce0e1c596a83c9009bd177d1548 104 Gene3D G3DSA:3.10.180.10 3 102 4.5E-4 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS15330 704429ab5973b967aeb7ee4d5c85d459 601 Gene3D G3DSA:1.20.1560.10 12 345 3.0E-64 T 29-03-2018 CVS48_RS15330 704429ab5973b967aeb7ee4d5c85d459 601 SUPERFAMILY SSF52540 345 591 2.34E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS15330 704429ab5973b967aeb7ee4d5c85d459 601 Pfam PF00664 ABC transporter transmembrane region 37 310 2.7E-42 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS15330 704429ab5973b967aeb7ee4d5c85d459 601 Gene3D G3DSA:3.40.50.300 346 597 4.5E-78 T 29-03-2018 CVS48_RS15330 704429ab5973b967aeb7ee4d5c85d459 601 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS15330 704429ab5973b967aeb7ee4d5c85d459 601 SMART SM00382 381 573 4.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS15330 704429ab5973b967aeb7ee4d5c85d459 601 SUPERFAMILY SSF90123 18 344 7.59E-67 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS15330 704429ab5973b967aeb7ee4d5c85d459 601 Pfam PF00005 ABC transporter 372 521 3.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 9.9E-38 T 29-03-2018 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 9.9E-38 T 29-03-2018 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 9.9E-38 T 29-03-2018 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 9.9E-38 T 29-03-2018 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 9.9E-38 T 29-03-2018 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 Gene3D G3DSA:1.10.275.10 6 110 1.3E-12 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 3.8E-21 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 3.8E-21 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 3.8E-21 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 3.8E-21 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 467 30.902 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 TIGRFAM TIGR00838 argH: argininosuccinate lyase 39 467 4.8E-113 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 SUPERFAMILY SSF48557 34 469 2.65E-102 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 Pfam PF00206 Lyase 76 304 9.1E-43 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 Gene3D G3DSA:1.10.40.30 380 446 1.6E-16 T 29-03-2018 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 Pfam PF14698 Argininosuccinate lyase C-terminal 368 445 9.6E-18 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS16370 ddfadfe04302c418a1646abb5128c5df 507 Gene3D G3DSA:1.20.200.10 111 379 3.0E-72 T 29-03-2018 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 13 407 1.5E-120 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 Gene3D G3DSA:3.40.50.620 7 230 4.2E-57 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 SUPERFAMILY SSF55174 327 404 3.4E-19 T 29-03-2018 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 223 235 2.1E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 58 80 2.1E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 173 188 2.1E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 190 212 2.1E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 10 407 47.832 T 29-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 SMART SM00363 347 408 1.8E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 SUPERFAMILY SSF52374 18 328 1.13E-88 T 29-03-2018 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 Gene3D G3DSA:1.10.240.10 231 331 1.2E-27 T 29-03-2018 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 64 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 Pfam PF00579 tRNA synthetases class I (W and Y) 45 328 2.8E-73 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 Pfam PF01479 S4 domain 349 391 1.3E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS02980 f9c08051f2e5e3594d569720e94cf0dc 409 Gene3D G3DSA:3.10.290.10 332 406 1.0E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS17060 9de7f4e5db7dd98d25f2f701ba71ee1d 307 PIRSF PIRSF017082 1 307 9.0E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17060 9de7f4e5db7dd98d25f2f701ba71ee1d 307 Gene3D G3DSA:3.40.190.10 126 281 6.7E-13 T 29-03-2018 CVS48_RS17060 9de7f4e5db7dd98d25f2f701ba71ee1d 307 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 32 303 1.9E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17060 9de7f4e5db7dd98d25f2f701ba71ee1d 307 SUPERFAMILY SSF53850 99 269 1.09E-14 T 29-03-2018 CVS48_RS14725 65fa11c197497b9def23867d62375d70 78 Gene3D G3DSA:2.30.30.100 5 74 1.6E-33 T 29-03-2018 CVS48_RS14725 65fa11c197497b9def23867d62375d70 78 SUPERFAMILY SSF50182 8 70 3.47E-24 T 29-03-2018 IPR010920 LSM domain CVS48_RS14725 65fa11c197497b9def23867d62375d70 78 Pfam PF17209 Hfq protein 8 69 1.9E-31 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CVS48_RS14725 65fa11c197497b9def23867d62375d70 78 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 3.9E-29 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CVS48_RS14725 65fa11c197497b9def23867d62375d70 78 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 28.324 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CVS48_RS01085 bfe93ca7baa374ed45af6ebe9fe90de6 220 Gene3D G3DSA:1.20.950.20 9 214 2.4E-18 T 29-03-2018 CVS48_RS01085 bfe93ca7baa374ed45af6ebe9fe90de6 220 SUPERFAMILY SSF81342 13 188 4.55E-22 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CVS48_RS01085 bfe93ca7baa374ed45af6ebe9fe90de6 220 Pfam PF01292 Prokaryotic cytochrome b561 16 184 1.1E-15 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 240 468 5.7E-76 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 Gene3D G3DSA:4.10.320.10 177 227 1.5E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 SUPERFAMILY SSF52777 236 468 8.9E-76 T 29-03-2018 CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 Pfam PF02817 e3 binding domain 182 216 1.1E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 SUPERFAMILY SSF51230 2 95 1.7E-23 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 Gene3D G3DSA:3.30.559.10 228 470 3.7E-74 T 29-03-2018 CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 SUPERFAMILY SSF47005 176 221 7.19E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 Gene3D G3DSA:3.90.1170.30 2 47 1.5E-14 T 29-03-2018 CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 Pfam PF00364 Biotin-requiring enzyme 6 76 4.6E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS16080 26c7360a68da4e3266f07274e2da8a25 470 Gene3D G3DSA:2.40.50.100 48 169 0.21 T 29-03-2018 CVS48_RS17305 26d2f8edabf3afcdc70d1b92a8859e74 256 SUPERFAMILY SSF51556 1 253 2.98E-88 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS17305 26d2f8edabf3afcdc70d1b92a8859e74 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CVS48_RS17305 26d2f8edabf3afcdc70d1b92a8859e74 256 Pfam PF01026 TatD related DNase 3 252 3.3E-78 T 29-03-2018 IPR001130 TatD family GO:0016788 CVS48_RS17305 26d2f8edabf3afcdc70d1b92a8859e74 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 252 9.5E-83 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CVS48_RS17305 26d2f8edabf3afcdc70d1b92a8859e74 256 Gene3D G3DSA:3.20.20.140 1 256 1.3E-84 T 29-03-2018 CVS48_RS17305 26d2f8edabf3afcdc70d1b92a8859e74 256 PIRSF PIRSF005902 1 256 1.1E-79 T 29-03-2018 IPR001130 TatD family GO:0016788 CVS48_RS17305 26d2f8edabf3afcdc70d1b92a8859e74 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 188 204 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CVS48_RS01010 4b533de0ae7bb11294b9c43306ccfc4e 513 Gene3D G3DSA:2.70.50.50 36 218 3.9E-42 T 29-03-2018 CVS48_RS01010 4b533de0ae7bb11294b9c43306ccfc4e 513 SMART SM00495 457 508 2.5E-9 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CVS48_RS01010 4b533de0ae7bb11294b9c43306ccfc4e 513 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 36 215 5.9E-30 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CVS48_RS01010 4b533de0ae7bb11294b9c43306ccfc4e 513 Gene3D G3DSA:2.10.10.20 454 512 3.2E-11 T 29-03-2018 CVS48_RS01010 4b533de0ae7bb11294b9c43306ccfc4e 513 Gene3D G3DSA:2.60.40.10 331 422 4.5E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS01010 4b533de0ae7bb11294b9c43306ccfc4e 513 SUPERFAMILY SSF81296 36 216 2.24E-35 T 29-03-2018 IPR014756 Immunoglobulin E-set CVS48_RS17650 af694054210b2d131567f8db9b51c096 326 Gene3D G3DSA:3.40.190.10 124 267 6.7E-10 T 29-03-2018 CVS48_RS17650 af694054210b2d131567f8db9b51c096 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 2.5E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17650 af694054210b2d131567f8db9b51c096 326 PIRSF PIRSF017082 1 325 4.6E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17650 af694054210b2d131567f8db9b51c096 326 SUPERFAMILY SSF53850 119 288 1.21E-12 T 29-03-2018 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 SUPERFAMILY SSF53732 7 592 8.76E-180 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 Pfam PF00330 Aconitase family (aconitate hydratase) 68 542 1.5E-151 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 Gene3D G3DSA:3.40.1060.10 234 368 3.0E-39 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 ProSitePatterns PS00450 Aconitase family signature 1. 407 423 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 SUPERFAMILY SSF52016 610 867 3.53E-61 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 34 867 2.3E-287 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 Gene3D G3DSA:3.30.499.10 38 233 2.5E-58 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 PRINTS PR00415 Aconitase family signature 143 156 6.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 PRINTS PR00415 Aconitase family signature 473 486 6.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 PRINTS PR00415 Aconitase family signature 197 210 6.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 PRINTS PR00415 Aconitase family signature 411 422 6.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 PRINTS PR00415 Aconitase family signature 366 380 6.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 PRINTS PR00415 Aconitase family signature 273 286 6.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 PRINTS PR00415 Aconitase family signature 287 300 6.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 PRINTS PR00415 Aconitase family signature 211 226 6.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 PRINTS PR00415 Aconitase family signature 167 175 6.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 Gene3D G3DSA:3.20.19.10 635 869 2.0E-62 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 Pfam PF00694 Aconitase C-terminal domain 668 795 1.5E-33 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 ProSitePatterns PS01244 Aconitase family signature 2. 473 486 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS12260 85c92d60ae010c09448c7f9f144e3cdd 884 Gene3D G3DSA:3.30.499.10 369 564 1.1E-47 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS08625 201811df94b858d5a9c92bf7b93a0b6e 213 Gene3D G3DSA:1.10.10.60 6 69 5.1E-15 T 29-03-2018 CVS48_RS08625 201811df94b858d5a9c92bf7b93a0b6e 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 7.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS08625 201811df94b858d5a9c92bf7b93a0b6e 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 7.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS08625 201811df94b858d5a9c92bf7b93a0b6e 213 Gene3D G3DSA:1.10.357.10 70 213 4.3E-15 T 29-03-2018 CVS48_RS08625 201811df94b858d5a9c92bf7b93a0b6e 213 SUPERFAMILY SSF46689 19 90 1.49E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS08625 201811df94b858d5a9c92bf7b93a0b6e 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 2.0E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS08625 201811df94b858d5a9c92bf7b93a0b6e 213 SUPERFAMILY SSF48498 88 210 1.42E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS04505 c7fbbef778d3a5b34c14d2fdbbb4eef9 336 ProDom PD024016 LIPOPOLYSACCHARIDE BIOSYNTHESIS CORE RFAZ WAAZ 78 310 1.0E-6 T 29-03-2018 CVS48_RS04505 c7fbbef778d3a5b34c14d2fdbbb4eef9 336 Gene3D G3DSA:3.90.1480.10 73 324 5.0E-27 T 29-03-2018 CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 1.2E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 SUPERFAMILY SSF46785 9 114 1.36E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 Pfam PF03466 LysR substrate binding domain 91 297 1.2E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 SUPERFAMILY SSF53850 91 300 3.8E-31 T 29-03-2018 CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 Gene3D G3DSA:3.40.190.10 175 265 3.4E-17 T 29-03-2018 CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 Gene3D G3DSA:3.40.190.10 91 174 2.7E-13 T 29-03-2018 CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 Gene3D G3DSA:1.10.10.10 1 88 6.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15295 5f0ed5bab103b83b2a0b16a474b89e6c 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15825 ed53cdf8d95b6d46a7fe72159c1f5bf7 699 Gene3D G3DSA:2.170.130.10 24 166 7.4E-26 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS15825 ed53cdf8d95b6d46a7fe72159c1f5bf7 699 Pfam PF00593 TonB dependent receptor 226 698 5.2E-59 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS15825 ed53cdf8d95b6d46a7fe72159c1f5bf7 699 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 682 699 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS15825 ed53cdf8d95b6d46a7fe72159c1f5bf7 699 Gene3D G3DSA:2.40.170.20 168 699 2.7E-78 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS15825 ed53cdf8d95b6d46a7fe72159c1f5bf7 699 SUPERFAMILY SSF56935 27 699 3.26E-128 T 29-03-2018 CVS48_RS15825 ed53cdf8d95b6d46a7fe72159c1f5bf7 699 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 155 2.1E-18 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS15825 ed53cdf8d95b6d46a7fe72159c1f5bf7 699 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 63 699 1.6E-107 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS27320 87fd200e1a01542eb8a50736f70a0f13 209 SUPERFAMILY SSF64153 1 202 4.84E-53 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CVS48_RS27320 87fd200e1a01542eb8a50736f70a0f13 209 Gene3D G3DSA:3.40.50.10260 1 203 6.5E-53 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CVS48_RS27320 87fd200e1a01542eb8a50736f70a0f13 209 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 201 21.825 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CVS48_RS27320 87fd200e1a01542eb8a50736f70a0f13 209 Pfam PF03853 YjeF-related protein N-terminus 21 178 1.4E-39 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CVS48_RS27320 87fd200e1a01542eb8a50736f70a0f13 209 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 12 200 2.6E-30 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CVS48_RS04520 8caa4538fc756c43b5f32062a127c958 318 Gene3D G3DSA:3.40.190.10 95 190 6.4E-17 T 29-03-2018 CVS48_RS04520 8caa4538fc756c43b5f32062a127c958 318 SUPERFAMILY SSF53850 113 297 2.17E-25 T 29-03-2018 CVS48_RS04520 8caa4538fc756c43b5f32062a127c958 318 Gene3D G3DSA:3.40.190.10 191 265 6.7E-6 T 29-03-2018 CVS48_RS04520 8caa4538fc756c43b5f32062a127c958 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 2.3E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04520 8caa4538fc756c43b5f32062a127c958 318 Pfam PF03466 LysR substrate binding domain 96 295 1.4E-23 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS04520 8caa4538fc756c43b5f32062a127c958 318 SUPERFAMILY SSF46785 8 94 9.14E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04520 8caa4538fc756c43b5f32062a127c958 318 Gene3D G3DSA:1.10.10.10 3 90 5.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16515 2e1ca06e93c89ade9213453c09fb335f 322 Gene3D G3DSA:1.10.3470.10 6 302 9.6E-39 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS16515 2e1ca06e93c89ade9213453c09fb335f 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 28 297 2.7E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS07340 f2c7c54fd34fbd789b910615d689ec77 292 Gene3D G3DSA:1.10.3470.10 1 279 5.9E-47 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS07340 f2c7c54fd34fbd789b910615d689ec77 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 276 3.7E-44 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS26395 65c95accd9baab3b549cf80bea594f6f 223 Pfam PF00072 Response regulator receiver domain 3 112 4.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS26395 65c95accd9baab3b549cf80bea594f6f 223 SUPERFAMILY SSF52172 1 170 8.4E-40 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS26395 65c95accd9baab3b549cf80bea594f6f 223 SMART SM00862 145 218 9.4E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS26395 65c95accd9baab3b549cf80bea594f6f 223 SMART SM00448 1 112 2.0E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS26395 65c95accd9baab3b549cf80bea594f6f 223 Gene3D G3DSA:3.40.50.2300 1 118 4.8E-37 T 29-03-2018 CVS48_RS26395 65c95accd9baab3b549cf80bea594f6f 223 Gene3D G3DSA:1.10.10.10 119 223 5.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26395 65c95accd9baab3b549cf80bea594f6f 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 4.7E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 Gene3D G3DSA:3.30.70.270 272 443 1.9E-67 T 29-03-2018 CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 SMART SM00091 8 77 1.8 T 29-03-2018 IPR000014 PAS domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 SMART SM00091 150 217 8.5E-4 T 29-03-2018 IPR000014 PAS domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 Pfam PF13426 PAS domain 21 123 4.9E-13 T 29-03-2018 IPR000014 PAS domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 SMART SM00267 265 436 8.9E-70 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 131 5.6E-19 T 29-03-2018 IPR000014 PAS domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 SUPERFAMILY SSF55073 281 438 3.3E-52 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 Pfam PF00990 Diguanylate cyclase, GGDEF domain 276 432 9.4E-53 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 Gene3D G3DSA:3.30.450.20 3 149 1.5E-24 T 29-03-2018 CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 Gene3D G3DSA:3.20.20.450 444 690 3.8E-95 T 29-03-2018 IPR001633 EAL domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 SUPERFAMILY SSF141868 453 687 2.62E-85 T 29-03-2018 IPR001633 EAL domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 SUPERFAMILY SSF55785 21 131 2.42E-23 T 29-03-2018 IPR000014 PAS domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 Gene3D G3DSA:3.30.450.20 150 271 3.1E-13 T 29-03-2018 CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 274 434 2.8E-44 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 Pfam PF08448 PAS fold 157 265 1.2E-7 T 29-03-2018 IPR013656 PAS fold-4 CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 SUPERFAMILY SSF55785 121 263 3.38E-12 T 29-03-2018 IPR000014 PAS domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 SMART SM00086 82 124 0.0034 T 29-03-2018 IPR001610 PAC motif CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 SMART SM00052 446 688 1.0E-108 T 29-03-2018 IPR001633 EAL domain CVS48_RS04530 e80fe8656a581b8822d6b430bc444da5 694 Pfam PF00563 EAL domain 453 683 1.0E-71 T 29-03-2018 IPR001633 EAL domain CVS48_RS24900 71d86bbaeee4980ba1ff368abfe66614 304 Gene3D G3DSA:3.40.190.10 90 177 2.6E-14 T 29-03-2018 CVS48_RS24900 71d86bbaeee4980ba1ff368abfe66614 304 SUPERFAMILY SSF46785 2 112 9.25E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24900 71d86bbaeee4980ba1ff368abfe66614 304 Gene3D G3DSA:3.40.190.10 178 270 3.0E-18 T 29-03-2018 CVS48_RS24900 71d86bbaeee4980ba1ff368abfe66614 304 SUPERFAMILY SSF53850 90 293 2.81E-38 T 29-03-2018 CVS48_RS24900 71d86bbaeee4980ba1ff368abfe66614 304 Gene3D G3DSA:1.10.10.10 1 86 7.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24900 71d86bbaeee4980ba1ff368abfe66614 304 Pfam PF03466 LysR substrate binding domain 89 293 4.7E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS24900 71d86bbaeee4980ba1ff368abfe66614 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 9.4E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01625 df0218efb6dbf14c644f9d0470f2c520 255 Gene3D G3DSA:3.40.50.300 1 239 8.4E-52 T 29-03-2018 CVS48_RS01625 df0218efb6dbf14c644f9d0470f2c520 255 SMART SM00382 30 239 2.9E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01625 df0218efb6dbf14c644f9d0470f2c520 255 Pfam PF00005 ABC transporter 22 167 2.9E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS01625 df0218efb6dbf14c644f9d0470f2c520 255 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS01625 df0218efb6dbf14c644f9d0470f2c520 255 SUPERFAMILY SSF52540 5 238 2.72E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08780 8d43e3b95359727f1d7a72d6161e9f45 304 Pfam PF04909 Amidohydrolase 38 300 3.9E-41 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS08780 8d43e3b95359727f1d7a72d6161e9f45 304 Gene3D G3DSA:3.20.20.140 23 304 4.5E-43 T 29-03-2018 CVS48_RS08780 8d43e3b95359727f1d7a72d6161e9f45 304 SUPERFAMILY SSF51556 33 300 4.35E-79 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 Pfam PF00501 AMP-binding enzyme 84 525 1.3E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 SUPERFAMILY SSF56801 16 645 3.66E-175 T 29-03-2018 CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 Gene3D G3DSA:3.40.50.980 269 431 2.4E-38 T 29-03-2018 CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 Gene3D G3DSA:2.30.38.10 432 518 9.3E-10 T 29-03-2018 CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 25 82 1.7E-18 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 534 612 1.8E-24 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 Gene3D G3DSA:3.40.50.980 75 268 3.7E-50 T 29-03-2018 CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 263 274 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 3 648 50.257 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 21 645 7.6E-292 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CVS48_RS13690 a0a8d56833d25ba4ee7d6431ffe14b71 651 Gene3D G3DSA:3.30.300.30 519 629 1.2E-25 T 29-03-2018 CVS48_RS19140 a6566b9da652cb94bc137e05b36c9c74 199 SUPERFAMILY SSF55729 7 180 7.62E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS19140 a6566b9da652cb94bc137e05b36c9c74 199 Pfam PF13302 Acetyltransferase (GNAT) domain 17 154 6.8E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS19140 a6566b9da652cb94bc137e05b36c9c74 199 Gene3D G3DSA:3.40.630.30 4 197 2.6E-27 T 29-03-2018 CVS48_RS14640 acdaa3d069997ab0947e5488e92e08d5 283 SUPERFAMILY SSF75217 1 242 7.85E-89 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CVS48_RS14640 acdaa3d069997ab0947e5488e92e08d5 283 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 235 1.2E-83 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CVS48_RS14640 acdaa3d069997ab0947e5488e92e08d5 283 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 228 3.5E-56 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CVS48_RS14640 acdaa3d069997ab0947e5488e92e08d5 283 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 283 104.904 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CVS48_RS14640 acdaa3d069997ab0947e5488e92e08d5 283 Gene3D G3DSA:3.40.1280.10 1 181 1.8E-66 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CVS48_RS14640 acdaa3d069997ab0947e5488e92e08d5 283 Gene3D G3DSA:1.10.1270.20 182 256 2.1E-26 T 29-03-2018 CVS48_RS14640 acdaa3d069997ab0947e5488e92e08d5 283 PIRSF PIRSF000386 1 256 2.0E-87 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 PRINTS PR00415 Aconitase family signature 213 226 5.7E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 PRINTS PR00415 Aconitase family signature 112 120 5.7E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 PRINTS PR00415 Aconitase family signature 199 212 5.7E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 PRINTS PR00415 Aconitase family signature 403 416 5.7E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 PRINTS PR00415 Aconitase family signature 137 152 5.7E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 PRINTS PR00415 Aconitase family signature 347 358 5.7E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 PRINTS PR00415 Aconitase family signature 86 99 5.7E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 PRINTS PR00415 Aconitase family signature 290 304 5.7E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 PRINTS PR00415 Aconitase family signature 123 136 5.7E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 Pfam PF00330 Aconitase family (aconitate hydratase) 9 461 7.7E-139 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 ProSitePatterns PS01244 Aconitase family signature 2. 403 416 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 Gene3D G3DSA:3.40.1060.10 159 292 6.6E-34 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 ProSitePatterns PS00450 Aconitase family signature 1. 343 359 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 468 1.1E-189 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 Gene3D G3DSA:3.30.499.10 296 473 2.4E-52 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 Gene3D G3DSA:3.30.499.10 1 158 4.6E-35 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 470 51.447 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CVS48_RS07385 b806bf4e60618962714db697b377aea8 473 SUPERFAMILY SSF53732 3 469 4.71E-151 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 113 325 4.4E-54 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 SMART SM00878 342 452 6.7E-35 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Gene3D G3DSA:3.30.1490.20 117 199 1.3E-13 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 SUPERFAMILY SSF56059 81 330 4.42E-51 T 29-03-2018 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Gene3D G3DSA:3.90.226.10 849 1099 1.4E-47 T 29-03-2018 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Gene3D G3DSA:3.90.226.10 578 848 3.9E-46 T 29-03-2018 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Pfam PF01039 Carboxyl transferase domain 616 1083 4.0E-69 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 SUPERFAMILY SSF52096 594 848 1.99E-49 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 107 1.5E-39 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 526 543 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Gene3D G3DSA:3.30.470.20 202 455 4.5E-74 T 29-03-2018 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Gene3D G3DSA:2.40.50.100 502 571 5.6E-15 T 29-03-2018 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 SUPERFAMILY SSF51246 337 456 1.2E-26 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Pfam PF00364 Biotin-requiring enzyme 509 568 3.1E-13 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 SUPERFAMILY SSF52096 818 1085 1.39E-56 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 SUPERFAMILY SSF51230 493 570 8.11E-17 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Pfam PF02785 Biotin carboxylase C-terminal domain 342 452 1.1E-26 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 Gene3D G3DSA:3.40.50.20 1 116 2.5E-43 T 29-03-2018 CVS48_RS25550 3d686f33b3dbca69ebe20c54165741f1 1105 SUPERFAMILY SSF52440 2 109 1.15E-39 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS01835 7b0fdbd58d87eec0df17f6140e566344 460 Gene3D G3DSA:3.30.460.10 23 175 5.8E-51 T 29-03-2018 CVS48_RS01835 7b0fdbd58d87eec0df17f6140e566344 460 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 208 266 2.4E-18 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CVS48_RS01835 7b0fdbd58d87eec0df17f6140e566344 460 Pfam PF01743 Poly A polymerase head domain 55 179 2.4E-36 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CVS48_RS01835 7b0fdbd58d87eec0df17f6140e566344 460 Pfam PF12626 Polymerase A arginine-rich C-terminus 319 450 3.5E-41 T 29-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain CVS48_RS01835 7b0fdbd58d87eec0df17f6140e566344 460 SUPERFAMILY SSF81301 29 176 6.65E-41 T 29-03-2018 CVS48_RS01835 7b0fdbd58d87eec0df17f6140e566344 460 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 15 452 37.02 T 29-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 CVS48_RS01835 7b0fdbd58d87eec0df17f6140e566344 460 SUPERFAMILY SSF81891 178 410 3.14E-51 T 29-03-2018 CVS48_RS01835 7b0fdbd58d87eec0df17f6140e566344 460 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 26 448 1.8E-153 T 29-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 CVS48_RS01835 7b0fdbd58d87eec0df17f6140e566344 460 Gene3D G3DSA:1.10.3090.10 176 429 1.2E-40 T 29-03-2018 CVS48_RS15445 4e8a68484e8e72cc54d86638054dd41a 147 SUPERFAMILY SSF54637 11 137 2.55E-32 T 29-03-2018 IPR029069 HotDog domain CVS48_RS15445 4e8a68484e8e72cc54d86638054dd41a 147 Pfam PF13279 Thioesterase-like superfamily 19 123 3.3E-12 T 29-03-2018 CVS48_RS15445 4e8a68484e8e72cc54d86638054dd41a 147 PIRSF PIRSF003230 7 144 6.3E-22 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CVS48_RS15445 4e8a68484e8e72cc54d86638054dd41a 147 Gene3D G3DSA:3.10.129.10 8 147 2.8E-27 T 29-03-2018 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 PRINTS PR01033 Phytochrome signature 460 478 6.6E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 PRINTS PR01033 Phytochrome signature 158 177 6.6E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 PRINTS PR01033 Phytochrome signature 244 265 6.6E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 PRINTS PR01033 Phytochrome signature 426 445 6.6E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 Gene3D G3DSA:1.10.287.130 497 565 1.9E-11 T 29-03-2018 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 SMART SM00388 507 569 3.8E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 Gene3D G3DSA:3.30.565.10 574 729 5.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 SMART SM00387 613 724 3.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 SUPERFAMILY SSF47384 497 568 1.77E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 Pfam PF00512 His Kinase A (phospho-acceptor) domain 508 569 1.6E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 Pfam PF00360 Phytochrome region 326 500 3.0E-37 T 29-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 SMART SM00065 143 316 8.9E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 SUPERFAMILY SSF55781 294 494 1.96E-37 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 SUPERFAMILY SSF55781 130 309 1.85E-54 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 Gene3D G3DSA:3.30.450.20 3 115 1.4E-11 T 29-03-2018 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 Gene3D G3DSA:3.30.450.40 116 310 5.0E-39 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 SUPERFAMILY SSF55785 10 118 5.23E-24 T 29-03-2018 IPR000014 PAS domain CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 Pfam PF01590 GAF domain 144 307 9.1E-18 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 Pfam PF08446 PAS fold 16 116 3.6E-8 T 29-03-2018 IPR013654 PAS fold-2 GO:0006355 CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 SUPERFAMILY SSF55874 559 722 1.14E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS13775 25a5476c37887bf86b79bda0011806f2 730 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 614 722 2.2E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS23180 f8298238125bb015fabcb697799d4b01 422 Gene3D G3DSA:3.40.640.10 185 316 2.0E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS23180 f8298238125bb015fabcb697799d4b01 422 PIRSF PIRSF000521 163 420 9.3E-23 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS23180 f8298238125bb015fabcb697799d4b01 422 PIRSF PIRSF000521 18 161 7.2E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS23180 f8298238125bb015fabcb697799d4b01 422 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS23180 f8298238125bb015fabcb697799d4b01 422 Gene3D G3DSA:3.90.1150.10 317 420 1.4E-10 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS23180 f8298238125bb015fabcb697799d4b01 422 Gene3D G3DSA:3.90.1150.10 5 184 2.8E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS23180 f8298238125bb015fabcb697799d4b01 422 SUPERFAMILY SSF53383 5 419 2.29E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS23180 f8298238125bb015fabcb697799d4b01 422 Pfam PF00202 Aminotransferase class-III 22 416 2.0E-115 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS23180 f8298238125bb015fabcb697799d4b01 422 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 14 417 9.1E-163 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.6E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.6E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.6E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 207 1.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 SMART SM00448 4 121 3.5E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 Gene3D G3DSA:1.10.10.10 133 216 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 Gene3D G3DSA:3.40.50.2300 3 132 5.5E-23 T 29-03-2018 CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 SUPERFAMILY SSF52172 3 134 6.69E-21 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 SUPERFAMILY SSF46894 148 213 1.87E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 SMART SM00421 152 209 4.5E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12030 d78e3dffc55400bd9cfc52a42b658206 216 Pfam PF00072 Response regulator receiver domain 6 121 4.7E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS04585 0a2da0c23466c662a89b9bdff97d739c 193 Pfam PF04542 Sigma-70 region 2 42 106 2.1E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04585 0a2da0c23466c662a89b9bdff97d739c 193 Pfam PF08281 Sigma-70, region 4 133 185 2.3E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04585 0a2da0c23466c662a89b9bdff97d739c 193 SUPERFAMILY SSF88946 19 119 4.97E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04585 0a2da0c23466c662a89b9bdff97d739c 193 Gene3D G3DSA:1.10.10.10 108 190 9.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04585 0a2da0c23466c662a89b9bdff97d739c 193 SUPERFAMILY SSF88659 132 186 2.62E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04585 0a2da0c23466c662a89b9bdff97d739c 193 Gene3D G3DSA:1.10.1740.10 15 107 9.7E-19 T 29-03-2018 CVS48_RS04585 0a2da0c23466c662a89b9bdff97d739c 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 186 2.3E-21 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04370 56fb254880e780b0c16cff17a81b8086 145 Pfam PF00582 Universal stress protein family 1 145 8.3E-30 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS04370 56fb254880e780b0c16cff17a81b8086 145 PIRSF PIRSF006276 1 145 3.7E-19 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS04370 56fb254880e780b0c16cff17a81b8086 145 SUPERFAMILY SSF52402 1 145 8.37E-33 T 29-03-2018 CVS48_RS04370 56fb254880e780b0c16cff17a81b8086 145 Gene3D G3DSA:3.40.50.620 1 145 4.8E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS04370 56fb254880e780b0c16cff17a81b8086 145 PRINTS PR01438 Universal stress protein signature 105 117 2.4E-16 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS04370 56fb254880e780b0c16cff17a81b8086 145 PRINTS PR01438 Universal stress protein signature 2 20 2.4E-16 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS04370 56fb254880e780b0c16cff17a81b8086 145 PRINTS PR01438 Universal stress protein signature 123 145 2.4E-16 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 15 750 0.0 T 29-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 Gene3D G3DSA:3.40.50.300 458 668 3.3E-43 T 29-03-2018 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 Gene3D G3DSA:1.10.1780.10 13 156 1.1E-23 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 Gene3D G3DSA:3.40.50.300 181 366 1.9E-26 T 29-03-2018 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 SUPERFAMILY SSF81923 14 155 5.2E-54 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 SUPERFAMILY SSF52540 184 432 1.57E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 SMART SM00382 222 367 1.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 SMART SM00382 503 652 6.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 534 552 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 227 357 2.3E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 669 749 1.7E-21 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 Pfam PF07724 AAA domain (Cdc48 subfamily) 502 663 1.5E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 SUPERFAMILY SSF52540 453 754 1.67E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 SMART SM01086 669 759 1.4E-31 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 Gene3D G3DSA:1.10.8.60 367 453 3.5E-27 T 29-03-2018 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 507 525 3.6E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 3.6E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 611 625 3.6E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 578 596 3.6E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 Gene3D G3DSA:1.10.8.60 669 772 2.3E-20 T 29-03-2018 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 25 73 1.2E-11 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS22400 804dc4f2285ea8b45d8dbc8a84b34c54 782 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 318 330 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CVS48_RS20665 656851bd2ec2160cf868aec97d3e520c 341 Gene3D G3DSA:3.40.50.2300 7 162 1.3E-25 T 29-03-2018 CVS48_RS20665 656851bd2ec2160cf868aec97d3e520c 341 Pfam PF00990 Diguanylate cyclase, GGDEF domain 171 331 5.3E-47 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS20665 656851bd2ec2160cf868aec97d3e520c 341 SUPERFAMILY SSF55073 175 333 1.18E-48 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS20665 656851bd2ec2160cf868aec97d3e520c 341 Gene3D G3DSA:3.30.70.270 163 335 2.7E-51 T 29-03-2018 CVS48_RS20665 656851bd2ec2160cf868aec97d3e520c 341 SUPERFAMILY SSF52172 17 150 2.85E-28 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS20665 656851bd2ec2160cf868aec97d3e520c 341 Pfam PF00072 Response regulator receiver domain 20 132 4.4E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS20665 656851bd2ec2160cf868aec97d3e520c 341 SMART SM00267 159 335 7.7E-55 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS20665 656851bd2ec2160cf868aec97d3e520c 341 SMART SM00448 18 132 6.1E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS20665 656851bd2ec2160cf868aec97d3e520c 341 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 167 333 4.5E-50 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 Gene3D G3DSA:3.40.50.970 382 558 1.7E-41 T 29-03-2018 CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 SUPERFAMILY SSF52518 2 179 2.01E-50 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 Gene3D G3DSA:3.40.50.970 1 182 2.8E-52 T 29-03-2018 CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 437 456 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 173 6.5E-54 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 333 3.0E-31 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 SUPERFAMILY SSF52467 189 340 3.66E-41 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 SUPERFAMILY SSF52467 372 392 3.66E-41 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 SUPERFAMILY SSF52518 376 553 1.97E-55 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 Gene3D G3DSA:3.40.50.1220 190 381 3.9E-41 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS02400 0b9569b8656fb9eb2a5c3ee072a4a4fd 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 403 547 7.5E-40 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS19460 54269800759e5b4d8dce5003337e6921 232 Gene3D G3DSA:2.60.120.10 11 131 7.2E-49 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS19460 54269800759e5b4d8dce5003337e6921 232 PIRSF PIRSF006232 1 230 3.2E-54 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CVS48_RS19460 54269800759e5b4d8dce5003337e6921 232 Gene3D G3DSA:2.60.120.10 132 232 6.4E-31 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS19460 54269800759e5b4d8dce5003337e6921 232 Pfam PF02678 Pirin 8 119 2.0E-36 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CVS48_RS19460 54269800759e5b4d8dce5003337e6921 232 SUPERFAMILY SSF51182 1 231 4.93E-79 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS18575 47a870e172e4da4d6f731cac1192f6ae 366 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 265 356 2.0E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18575 47a870e172e4da4d6f731cac1192f6ae 366 SUPERFAMILY SSF55874 224 355 8.12E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18575 47a870e172e4da4d6f731cac1192f6ae 366 SUPERFAMILY SSF55785 19 133 2.24E-19 T 29-03-2018 IPR000014 PAS domain CVS48_RS18575 47a870e172e4da4d6f731cac1192f6ae 366 SMART SM00387 262 358 1.3E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18575 47a870e172e4da4d6f731cac1192f6ae 366 Gene3D G3DSA:3.30.450.20 9 184 2.7E-17 T 29-03-2018 CVS48_RS18575 47a870e172e4da4d6f731cac1192f6ae 366 Pfam PF13426 PAS domain 19 124 2.7E-7 T 29-03-2018 IPR000014 PAS domain CVS48_RS18575 47a870e172e4da4d6f731cac1192f6ae 366 Pfam PF07730 Histidine kinase 153 222 5.1E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CVS48_RS18575 47a870e172e4da4d6f731cac1192f6ae 366 Gene3D G3DSA:3.30.565.10 221 361 4.9E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18575 47a870e172e4da4d6f731cac1192f6ae 366 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 132 1.8E-12 T 29-03-2018 IPR000014 PAS domain CVS48_RS28005 aef63bda33b8849528e530c9e46e5da3 550 SUPERFAMILY SSF52540 2 270 4.98E-121 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28005 aef63bda33b8849528e530c9e46e5da3 550 Gene3D G3DSA:3.40.50.880 290 546 1.4E-74 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS28005 aef63bda33b8849528e530c9e46e5da3 550 SUPERFAMILY SSF52317 292 544 1.58E-86 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS28005 aef63bda33b8849528e530c9e46e5da3 550 Hamap MF_01227 CTP synthase [pyrG]. 2 543 51.013 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CVS48_RS28005 aef63bda33b8849528e530c9e46e5da3 550 Pfam PF06418 CTP synthase N-terminus 3 270 6.6E-125 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CVS48_RS28005 aef63bda33b8849528e530c9e46e5da3 550 TIGRFAM TIGR00337 PyrG: CTP synthase 1 538 4.4E-241 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CVS48_RS28005 aef63bda33b8849528e530c9e46e5da3 550 Gene3D G3DSA:3.40.50.300 1 289 1.6E-130 T 29-03-2018 CVS48_RS28005 aef63bda33b8849528e530c9e46e5da3 550 Pfam PF00117 Glutamine amidotransferase class-I 305 537 3.1E-56 T 29-03-2018 IPR017926 Glutamine amidotransferase CVS48_RS23985 f3e9b9ee0a80b6b9693e9ca192ad0c16 254 Gene3D G3DSA:1.10.10.10 7 91 6.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23985 f3e9b9ee0a80b6b9693e9ca192ad0c16 254 SMART SM00346 2 93 3.4E-17 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS23985 f3e9b9ee0a80b6b9693e9ca192ad0c16 254 Pfam PF01614 Bacterial transcriptional regulator 121 243 2.0E-30 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS23985 f3e9b9ee0a80b6b9693e9ca192ad0c16 254 SUPERFAMILY SSF55781 75 247 2.62E-52 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS23985 f3e9b9ee0a80b6b9693e9ca192ad0c16 254 Pfam PF09339 IclR helix-turn-helix domain 5 55 5.7E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS23985 f3e9b9ee0a80b6b9693e9ca192ad0c16 254 SUPERFAMILY SSF46785 3 76 1.32E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23985 f3e9b9ee0a80b6b9693e9ca192ad0c16 254 Gene3D G3DSA:3.30.450.40 92 251 2.6E-52 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 SUPERFAMILY SSF102114 161 405 7.59E-59 T 29-03-2018 CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 SMART SM00729 179 400 2.7E-54 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 36 470 4.7E-150 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 183 203 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 Pfam PF04055 Radical SAM superfamily 183 358 2.5E-29 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 Pfam PF00919 Uncharacterized protein family UPF0004 36 136 9.3E-30 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 35 473 74.125 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 Pfam PF01938 TRAM domain 412 472 2.2E-15 T 29-03-2018 IPR002792 TRAM domain CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 36 472 2.4E-180 T 29-03-2018 CVS48_RS12970 bc2eaf53208a70ba824de41fadbd6e79 483 Gene3D G3DSA:3.80.30.20 176 414 5.5E-54 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 Pfam PF07729 FCD domain 100 225 1.3E-21 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 SMART SM00895 99 227 7.0E-23 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 SUPERFAMILY SSF48008 98 235 1.18E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 Gene3D G3DSA:1.10.10.10 1 78 4.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 7.1E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 SUPERFAMILY SSF46785 9 80 4.45E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 SMART SM00345 17 76 8.3E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18080 a03e1457f533d6d3c21a4361f3890be5 242 Gene3D G3DSA:1.20.120.530 87 242 7.9E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS18415 cebf247b0775077432e04b0065088da1 252 Gene3D G3DSA:3.40.50.1820 3 243 1.2E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS18415 cebf247b0775077432e04b0065088da1 252 SUPERFAMILY SSF53474 10 238 1.23E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS18415 cebf247b0775077432e04b0065088da1 252 Pfam PF00326 Prolyl oligopeptidase family 43 239 2.2E-10 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CVS48_RS18415 cebf247b0775077432e04b0065088da1 252 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 84 114 - T 29-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 CVS48_RS03760 8b5319596a19ff05bd5f97319d78e5ee 228 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 219 4.5E-100 T 29-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 CVS48_RS03760 8b5319596a19ff05bd5f97319d78e5ee 228 Gene3D G3DSA:3.40.50.2300 1 123 6.5E-34 T 29-03-2018 CVS48_RS03760 8b5319596a19ff05bd5f97319d78e5ee 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 9.4E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS03760 8b5319596a19ff05bd5f97319d78e5ee 228 SUPERFAMILY SSF52172 1 177 2.57E-40 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS03760 8b5319596a19ff05bd5f97319d78e5ee 228 SMART SM00448 1 111 7.0E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS03760 8b5319596a19ff05bd5f97319d78e5ee 228 SMART SM00862 144 219 2.8E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS03760 8b5319596a19ff05bd5f97319d78e5ee 228 Gene3D G3DSA:1.10.10.10 124 224 3.0E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03760 8b5319596a19ff05bd5f97319d78e5ee 228 Pfam PF00072 Response regulator receiver domain 3 112 2.3E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS28065 752f483d098a7e13648231fbe7bb8df1 150 Pfam PF13673 Acetyltransferase (GNAT) domain 45 149 1.2E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS28065 752f483d098a7e13648231fbe7bb8df1 150 Gene3D G3DSA:3.40.630.30 2 150 5.2E-28 T 29-03-2018 CVS48_RS28065 752f483d098a7e13648231fbe7bb8df1 150 SUPERFAMILY SSF55729 1 149 1.95E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS28080 47514dd9e74e8f1eb886faad7501a3c9 150 SUPERFAMILY SSF54637 17 143 1.56E-29 T 29-03-2018 IPR029069 HotDog domain CVS48_RS28080 47514dd9e74e8f1eb886faad7501a3c9 150 Pfam PF13279 Thioesterase-like superfamily 25 142 4.1E-17 T 29-03-2018 CVS48_RS28080 47514dd9e74e8f1eb886faad7501a3c9 150 Gene3D G3DSA:3.10.129.10 15 145 1.6E-30 T 29-03-2018 CVS48_RS27275 d7cf675455c93717a8876ca1ef49bbed 156 Gene3D G3DSA:3.10.129.10 7 148 6.6E-29 T 29-03-2018 CVS48_RS27275 d7cf675455c93717a8876ca1ef49bbed 156 Pfam PF03061 Thioesterase superfamily 62 135 9.7E-13 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CVS48_RS27275 d7cf675455c93717a8876ca1ef49bbed 156 SUPERFAMILY SSF54637 13 140 5.95E-30 T 29-03-2018 IPR029069 HotDog domain CVS48_RS27275 d7cf675455c93717a8876ca1ef49bbed 156 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 33 143 1.3E-26 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CVS48_RS27275 d7cf675455c93717a8876ca1ef49bbed 156 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 33 145 2.9E-49 T 29-03-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 CVS48_RS10180 06b9ef5db81a5e33839ad7d25d6933be 197 SUPERFAMILY SSF160519 1 192 1.83E-70 T 29-03-2018 IPR009569 Amino acid synthesis, putative CVS48_RS10180 06b9ef5db81a5e33839ad7d25d6933be 197 Pfam PF06684 Amino acid synthesis 5 181 1.4E-68 T 29-03-2018 IPR009569 Amino acid synthesis, putative CVS48_RS10180 06b9ef5db81a5e33839ad7d25d6933be 197 Gene3D G3DSA:3.30.1330.110 3 192 4.2E-73 T 29-03-2018 IPR009569 Amino acid synthesis, putative CVS48_RS13395 11688ab1874705940fffca2226aeff43 479 Pfam PF01425 Amidase 40 457 5.3E-82 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS13395 11688ab1874705940fffca2226aeff43 479 ProSitePatterns PS00571 Amidases signature. 150 181 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CVS48_RS13395 11688ab1874705940fffca2226aeff43 479 Gene3D G3DSA:3.90.1300.10 2 475 9.5E-114 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS13395 11688ab1874705940fffca2226aeff43 479 SUPERFAMILY SSF75304 3 466 2.35E-108 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS25265 da5b6a12e02a446ec0fe536c85f96c83 334 PIRSF PIRSF018266 12 333 1.9E-75 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS25265 da5b6a12e02a446ec0fe536c85f96c83 334 Pfam PF04773 FecR protein 126 219 3.4E-11 T 29-03-2018 IPR006860 FecR protein CVS48_RS25265 da5b6a12e02a446ec0fe536c85f96c83 334 Pfam PF16220 Domain of unknown function (DUF4880) 24 64 1.1E-11 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS04645 51b30038f08d5063dc4c8276d7250838 508 Pfam PF00144 Beta-lactamase 38 365 1.1E-59 T 29-03-2018 IPR001466 Beta-lactamase-related CVS48_RS04645 51b30038f08d5063dc4c8276d7250838 508 Gene3D G3DSA:3.40.710.10 25 372 1.1E-72 T 29-03-2018 CVS48_RS04645 51b30038f08d5063dc4c8276d7250838 508 SUPERFAMILY SSF56601 33 372 6.73E-72 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS04645 51b30038f08d5063dc4c8276d7250838 508 Pfam PF11954 Domain of unknown function (DUF3471) 406 495 6.2E-13 T 29-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal CVS48_RS26690 4a2380769fd87bda0f2b71b060c04ab7 73 SUPERFAMILY SSF50182 22 72 3.76E-12 T 29-03-2018 IPR010920 LSM domain CVS48_RS26690 4a2380769fd87bda0f2b71b060c04ab7 73 Pfam PF06004 Bacterial protein of unknown function (DUF903) 24 71 1.6E-16 T 29-03-2018 IPR010305 Protein of unknown function DUF903 CVS48_RS26690 4a2380769fd87bda0f2b71b060c04ab7 73 Gene3D G3DSA:2.30.30.100 22 71 4.6E-18 T 29-03-2018 CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 Gene3D G3DSA:3.40.190.10 182 264 1.8E-20 T 29-03-2018 CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 SUPERFAMILY SSF53850 92 290 4.03E-35 T 29-03-2018 CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 Gene3D G3DSA:3.40.190.10 91 181 1.7E-22 T 29-03-2018 CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 Gene3D G3DSA:1.10.10.10 1 88 1.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 SUPERFAMILY SSF46785 2 80 1.58E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 Pfam PF03466 LysR substrate binding domain 91 291 1.7E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS22505 1c846c8f95fa9ef229e54ec03df055aa 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 59 4.2E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19605 6502e3120fedc3cd0e4bada53e0fc701 1208 Pfam PF01968 Hydantoinase/oxoprolinase 204 490 9.1E-114 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CVS48_RS19605 6502e3120fedc3cd0e4bada53e0fc701 1208 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 6 185 2.6E-59 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CVS48_RS19605 6502e3120fedc3cd0e4bada53e0fc701 1208 Pfam PF02538 Hydantoinase B/oxoprolinase 690 1207 1.3E-199 T 29-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 CVS48_RS19605 6502e3120fedc3cd0e4bada53e0fc701 1208 Gene3D G3DSA:3.30.420.40 7 183 0.22 T 29-03-2018 CVS48_RS19110 a68a330c68052bf4fb4e1e39a1ec3c12 424 Gene3D G3DSA:1.20.1250.20 230 418 7.6E-11 T 29-03-2018 CVS48_RS19110 a68a330c68052bf4fb4e1e39a1ec3c12 424 Pfam PF07690 Major Facilitator Superfamily 31 251 5.0E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS19110 a68a330c68052bf4fb4e1e39a1ec3c12 424 Gene3D G3DSA:1.20.1250.20 24 214 2.0E-34 T 29-03-2018 CVS48_RS19110 a68a330c68052bf4fb4e1e39a1ec3c12 424 SUPERFAMILY SSF103473 13 413 1.31E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 Gene3D G3DSA:1.10.10.10 3 73 4.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 70 5.5E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 Gene3D G3DSA:1.20.120.530 74 224 1.4E-18 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 SMART SM00895 81 206 1.2E-8 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 Pfam PF07729 FCD domain 82 203 5.8E-12 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 SMART SM00345 13 71 1.4E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 6.9E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 6.9E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 SUPERFAMILY SSF48008 78 214 3.66E-14 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS03815 7d290f7e11ec99bacb1f50e91e1de867 237 SUPERFAMILY SSF46785 5 75 1.85E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Gene3D G3DSA:1.25.40.10 1 85 1.0E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Gene3D G3DSA:1.25.40.10 368 426 9.7E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Gene3D G3DSA:1.25.40.10 187 215 3.0E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Pfam PF13432 Tetratricopeptide repeat 278 339 8.4E-6 T 29-03-2018 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Pfam PF13432 Tetratricopeptide repeat 149 199 5.0E-4 T 29-03-2018 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Gene3D G3DSA:1.25.40.10 216 277 4.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 SUPERFAMILY SSF48452 7 243 2.75E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Gene3D G3DSA:1.25.40.10 130 186 9.7E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 SUPERFAMILY SSF48452 305 471 9.63E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 SMART SM00028 443 476 10.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 SMART SM00028 408 441 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 SMART SM00028 306 339 0.051 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 SMART SM00028 171 204 25.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 SMART SM00028 137 170 0.014 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 SMART SM00028 205 238 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 SMART SM00028 35 68 80.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Gene3D G3DSA:1.25.40.10 427 498 1.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Gene3D G3DSA:1.25.40.10 278 367 4.0E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS00015 6f36619417758049d24213c598a79fcd 510 Gene3D G3DSA:1.25.40.10 86 129 0.012 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 Gene3D G3DSA:2.40.128.130 1088 1430 1.3E-59 T 29-03-2018 CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 SUPERFAMILY SSF51126 572 1018 3.45E-15 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 Pfam PF03797 Autotransporter beta-domain 1156 1410 1.8E-62 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 871 902 2.3E-8 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 782 813 8.7E-11 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 Pfam PF12951 Passenger-associated-transport-repeat 567 590 0.0028 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 Pfam PF12951 Passenger-associated-transport-repeat 783 812 6.0E-10 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 Pfam PF12951 Passenger-associated-transport-repeat 872 901 2.8E-5 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 24 1.8E-7 T 29-03-2018 IPR024973 ESPR domain CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 940 1429 1.1E-49 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 SUPERFAMILY SSF103515 1096 1429 3.01E-64 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 295 332 3.4E-10 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 335 381 3.6E-7 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 125 169 1.5E-9 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 385 434 2.1E-11 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 437 484 1.3E-9 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS17530 110cabd9342b1b54189059e9212383a4 1430 SMART SM00869 1153 1420 6.6E-48 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS05915 c5538c05c3251014aba752412a340c4d 355 Gene3D G3DSA:3.40.190.10 270 335 1.2E-4 T 29-03-2018 CVS48_RS05915 c5538c05c3251014aba752412a340c4d 355 Pfam PF13416 Bacterial extracellular solute-binding protein 56 319 1.9E-32 T 29-03-2018 CVS48_RS05915 c5538c05c3251014aba752412a340c4d 355 SUPERFAMILY SSF53850 34 353 1.83E-53 T 29-03-2018 CVS48_RS05915 c5538c05c3251014aba752412a340c4d 355 Gene3D G3DSA:3.40.190.10 31 150 9.0E-16 T 29-03-2018 CVS48_RS05915 c5538c05c3251014aba752412a340c4d 355 Gene3D G3DSA:3.40.190.10 151 269 3.7E-23 T 29-03-2018 CVS48_RS04840 67a849f55ab04666068cbefe234026f4 1067 Gene3D G3DSA:3.40.50.300 2 391 3.9E-38 T 29-03-2018 CVS48_RS04840 67a849f55ab04666068cbefe234026f4 1067 Pfam PF13361 UvrD-like helicase C-terminal domain 628 801 1.5E-14 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CVS48_RS04840 67a849f55ab04666068cbefe234026f4 1067 SUPERFAMILY SSF52540 10 168 7.44E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04840 67a849f55ab04666068cbefe234026f4 1067 SUPERFAMILY SSF52540 280 567 7.44E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04840 67a849f55ab04666068cbefe234026f4 1067 SUPERFAMILY SSF52540 594 736 7.44E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04840 67a849f55ab04666068cbefe234026f4 1067 SUPERFAMILY SSF52540 781 805 7.44E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04840 67a849f55ab04666068cbefe234026f4 1067 Gene3D G3DSA:3.40.50.300 558 830 9.2E-24 T 29-03-2018 CVS48_RS04840 67a849f55ab04666068cbefe234026f4 1067 Gene3D G3DSA:3.40.50.300 400 533 5.8E-9 T 29-03-2018 CVS48_RS04840 67a849f55ab04666068cbefe234026f4 1067 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 385 1.8E-45 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CVS48_RS02415 332ea69a763bab921015c836224c26c1 377 Pfam PF13518 Helix-turn-helix domain 12 62 6.5E-12 T 29-03-2018 CVS48_RS02415 332ea69a763bab921015c836224c26c1 377 Gene3D G3DSA:3.30.420.10 126 328 5.1E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS02415 332ea69a763bab921015c836224c26c1 377 SUPERFAMILY SSF46689 11 115 2.15E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS02415 332ea69a763bab921015c836224c26c1 377 Gene3D G3DSA:1.10.10.10 10 65 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02415 332ea69a763bab921015c836224c26c1 377 SUPERFAMILY SSF53098 130 302 3.67E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS02415 332ea69a763bab921015c836224c26c1 377 Pfam PF00665 Integrase core domain 134 257 2.2E-25 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS23815 332ea69a763bab921015c836224c26c1 377 Pfam PF13518 Helix-turn-helix domain 12 62 6.5E-12 T 29-03-2018 CVS48_RS23815 332ea69a763bab921015c836224c26c1 377 Gene3D G3DSA:3.30.420.10 126 328 5.1E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS23815 332ea69a763bab921015c836224c26c1 377 SUPERFAMILY SSF46689 11 115 2.15E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS23815 332ea69a763bab921015c836224c26c1 377 Gene3D G3DSA:1.10.10.10 10 65 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23815 332ea69a763bab921015c836224c26c1 377 SUPERFAMILY SSF53098 130 302 3.67E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS23815 332ea69a763bab921015c836224c26c1 377 Pfam PF00665 Integrase core domain 134 257 2.2E-25 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS20480 332ea69a763bab921015c836224c26c1 377 Pfam PF13518 Helix-turn-helix domain 12 62 6.5E-12 T 29-03-2018 CVS48_RS20480 332ea69a763bab921015c836224c26c1 377 Gene3D G3DSA:3.30.420.10 126 328 5.1E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS20480 332ea69a763bab921015c836224c26c1 377 SUPERFAMILY SSF46689 11 115 2.15E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS20480 332ea69a763bab921015c836224c26c1 377 Gene3D G3DSA:1.10.10.10 10 65 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20480 332ea69a763bab921015c836224c26c1 377 SUPERFAMILY SSF53098 130 302 3.67E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS20480 332ea69a763bab921015c836224c26c1 377 Pfam PF00665 Integrase core domain 134 257 2.2E-25 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 Gene3D G3DSA:1.20.5.1040 2 60 7.4E-5 T 29-03-2018 CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 SUPERFAMILY SSF47384 216 295 3.73E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 Gene3D G3DSA:3.30.565.10 283 447 3.5E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 Pfam PF08521 Two-component sensor kinase N-terminal 18 146 1.2E-5 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 427 2.6E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 2.6E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 405 2.6E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 SMART SM00387 339 450 7.8E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 295 7.8E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 SMART SM00388 231 296 1.0E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 SUPERFAMILY SSF55874 286 446 4.06E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 446 2.0E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11945 b9051aa8cfe4c40c64cfbf24cfc6193b 455 Gene3D G3DSA:1.10.287.130 221 282 5.2E-11 T 29-03-2018 CVS48_RS07220 b977c3bb1b55f2ef7a5220d71c50ca0b 270 Gene3D G3DSA:3.40.50.2300 7 110 3.4E-11 T 29-03-2018 CVS48_RS07220 b977c3bb1b55f2ef7a5220d71c50ca0b 270 Gene3D G3DSA:3.40.50.2300 111 270 2.8E-37 T 29-03-2018 CVS48_RS07220 b977c3bb1b55f2ef7a5220d71c50ca0b 270 SUPERFAMILY SSF53822 8 263 1.0E-37 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS07220 b977c3bb1b55f2ef7a5220d71c50ca0b 270 Pfam PF13377 Periplasmic binding protein-like domain 111 270 2.2E-26 T 29-03-2018 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Pfam PF13184 NusA-like KH domain 232 299 6.7E-25 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 SUPERFAMILY SSF54814 202 280 2.03E-28 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Pfam PF00575 S1 RNA binding domain 138 194 4.1E-6 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Gene3D G3DSA:1.10.150.20 427 492 2.2E-17 T 29-03-2018 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Gene3D G3DSA:1.10.150.20 358 423 2.9E-12 T 29-03-2018 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Gene3D G3DSA:3.30.1480.10 1 132 1.7E-43 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Gene3D G3DSA:3.30.300.20 280 349 2.4E-12 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 SUPERFAMILY SSF50249 135 201 2.17E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Gene3D G3DSA:3.30.300.20 201 278 1.3E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 SUPERFAMILY SSF47794 428 489 1.19E-14 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 343 2.0E-121 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Pfam PF08529 NusA N-terminal domain 4 127 1.1E-36 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 SUPERFAMILY SSF54814 281 344 2.42E-14 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 SUPERFAMILY SSF69705 1 129 2.88E-39 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 SMART SM00316 136 202 7.4E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 SUPERFAMILY SSF47794 358 418 9.58E-16 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Pfam PF14520 Helix-hairpin-helix domain 431 485 7.9E-8 T 29-03-2018 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 416 3.6E-18 T 29-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 439 488 1.2E-15 T 29-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 28.814 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CVS48_RS27165 6aab9310df0664db263b361abda3b275 492 Gene3D G3DSA:2.40.50.140 139 200 1.6E-13 T 29-03-2018 CVS48_RS02095 3af61dcf1b757c3886fa1336aafaf626 612 PIRSF PIRSF028304 1 611 9.2E-189 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CVS48_RS02095 3af61dcf1b757c3886fa1336aafaf626 612 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 4 611 1.4E-215 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CVS48_RS02095 3af61dcf1b757c3886fa1336aafaf626 612 Pfam PF05947 Type VI secretion system, TssF 5 609 6.0E-206 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CVS48_RS25340 c16e45b1268b25bdf38bc16883ec89b4 312 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 7 309 1.4E-69 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CVS48_RS25340 c16e45b1268b25bdf38bc16883ec89b4 312 Gene3D G3DSA:3.40.50.720 134 293 2.5E-33 T 29-03-2018 CVS48_RS25340 c16e45b1268b25bdf38bc16883ec89b4 312 Gene3D G3DSA:3.30.1780.10 1 133 5.9E-38 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CVS48_RS25340 c16e45b1268b25bdf38bc16883ec89b4 312 SUPERFAMILY SSF51735 1 308 6.1E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25340 c16e45b1268b25bdf38bc16883ec89b4 312 PIRSF PIRSF001439 1 311 1.3E-71 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CVS48_RS00560 15540c89dddd70ba08608142002cfb66 361 PIRSF PIRSF005508 4 356 1.2E-117 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CVS48_RS00560 15540c89dddd70ba08608142002cfb66 361 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 17 344 3.4E-117 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CVS48_RS00560 15540c89dddd70ba08608142002cfb66 361 Pfam PF01758 Sodium Bile acid symporter family 63 257 3.8E-35 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 Pfam PF00199 Catalase 8 388 1.1E-196 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 Gene3D G3DSA:2.40.180.10 1 358 7.0E-171 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 334 342 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 Pfam PF06628 Catalase-related immune-responsive 418 477 2.5E-23 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 PRINTS PR00067 Catalase signature 21 44 8.4E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 PRINTS PR00067 Catalase signature 124 142 8.4E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 PRINTS PR00067 Catalase signature 321 347 8.4E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 PRINTS PR00067 Catalase signature 289 316 8.4E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 PRINTS PR00067 Catalase signature 84 102 8.4E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 PRINTS PR00067 Catalase signature 105 122 8.4E-77 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 PIRSF PIRSF038928 1 481 8.4E-230 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 SUPERFAMILY SSF56634 3 480 2.49E-220 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS06060 d5be1e212de7bbc2c01f72bbcacd2b5f 481 SMART SM01060 8 392 9.7E-298 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS09575 33302cd2f9358b7d751b8f27399e6a41 309 Gene3D G3DSA:1.10.10.10 1 87 4.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09575 33302cd2f9358b7d751b8f27399e6a41 309 Pfam PF03466 LysR substrate binding domain 97 292 1.4E-13 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS09575 33302cd2f9358b7d751b8f27399e6a41 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.7E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09575 33302cd2f9358b7d751b8f27399e6a41 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 7.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09575 33302cd2f9358b7d751b8f27399e6a41 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 7.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09575 33302cd2f9358b7d751b8f27399e6a41 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 7.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09575 33302cd2f9358b7d751b8f27399e6a41 309 SUPERFAMILY SSF46785 3 82 2.53E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09575 33302cd2f9358b7d751b8f27399e6a41 309 SUPERFAMILY SSF53850 97 295 2.53E-15 T 29-03-2018 CVS48_RS09575 33302cd2f9358b7d751b8f27399e6a41 309 Gene3D G3DSA:3.40.190.10 95 198 5.6E-12 T 29-03-2018 CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.3E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 Pfam PF03466 LysR substrate binding domain 87 288 6.3E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 SUPERFAMILY SSF46785 1 109 1.85E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 SUPERFAMILY SSF53850 87 284 2.53E-34 T 29-03-2018 CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 Gene3D G3DSA:3.40.190.10 179 262 1.7E-12 T 29-03-2018 CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 Gene3D G3DSA:3.40.190.10 87 178 9.1E-14 T 29-03-2018 CVS48_RS28755 97ff96198fdb0fc916612858d5b4c418 298 Gene3D G3DSA:1.10.10.10 1 83 8.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 Gene3D G3DSA:1.10.10.10 1 84 6.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 Gene3D G3DSA:3.40.190.10 177 266 2.6E-25 T 29-03-2018 CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 SUPERFAMILY SSF46785 1 111 2.25E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 SUPERFAMILY SSF53850 90 292 1.9E-38 T 29-03-2018 CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 Gene3D G3DSA:3.40.190.10 89 176 3.0E-20 T 29-03-2018 CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 Pfam PF03466 LysR substrate binding domain 88 290 2.9E-43 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS02360 1149176025c066553af84dcb6d39ddff 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.7E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09020 34d67d9e7ffeba942ec7c38dd604260e 390 Gene3D G3DSA:3.40.630.10 9 235 1.4E-46 T 29-03-2018 CVS48_RS09020 34d67d9e7ffeba942ec7c38dd604260e 390 Gene3D G3DSA:3.40.630.10 249 389 9.4E-22 T 29-03-2018 CVS48_RS09020 34d67d9e7ffeba942ec7c38dd604260e 390 SUPERFAMILY SSF55031 184 297 1.83E-32 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS09020 34d67d9e7ffeba942ec7c38dd604260e 390 Pfam PF01546 Peptidase family M20/M25/M40 74 385 3.1E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS09020 34d67d9e7ffeba942ec7c38dd604260e 390 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 376 3.1E-109 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS09020 34d67d9e7ffeba942ec7c38dd604260e 390 Pfam PF07687 Peptidase dimerisation domain 186 280 4.8E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS09020 34d67d9e7ffeba942ec7c38dd604260e 390 PIRSF PIRSF005962 2 389 7.0E-123 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS09020 34d67d9e7ffeba942ec7c38dd604260e 390 SUPERFAMILY SSF53187 299 385 2.23E-83 T 29-03-2018 CVS48_RS09020 34d67d9e7ffeba942ec7c38dd604260e 390 SUPERFAMILY SSF53187 11 198 2.23E-83 T 29-03-2018 CVS48_RS28720 e158848c2d9e9bf91ecec9ce0d1135c7 147 SUPERFAMILY SSF54637 16 146 2.32E-23 T 29-03-2018 IPR029069 HotDog domain CVS48_RS28720 e158848c2d9e9bf91ecec9ce0d1135c7 147 Pfam PF03061 Thioesterase superfamily 60 120 7.6E-9 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CVS48_RS28720 e158848c2d9e9bf91ecec9ce0d1135c7 147 Gene3D G3DSA:3.10.129.10 7 147 3.8E-24 T 29-03-2018 CVS48_RS28720 e158848c2d9e9bf91ecec9ce0d1135c7 147 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 33 119 5.0E-11 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CVS48_RS09995 343b9640113c43a367a2d28f89666755 332 Pfam PF00107 Zinc-binding dehydrogenase 158 273 1.6E-26 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS09995 343b9640113c43a367a2d28f89666755 332 Gene3D G3DSA:3.90.180.10 262 331 8.9E-7 T 29-03-2018 CVS48_RS09995 343b9640113c43a367a2d28f89666755 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 93 9.8E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS09995 343b9640113c43a367a2d28f89666755 332 SUPERFAMILY SSF51735 119 295 3.59E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09995 343b9640113c43a367a2d28f89666755 332 SMART SM00829 17 330 7.8E-48 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS09995 343b9640113c43a367a2d28f89666755 332 Gene3D G3DSA:3.90.180.10 2 144 8.0E-37 T 29-03-2018 CVS48_RS09995 343b9640113c43a367a2d28f89666755 332 Gene3D G3DSA:3.40.50.720 145 261 2.4E-34 T 29-03-2018 CVS48_RS09995 343b9640113c43a367a2d28f89666755 332 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 8 331 4.5E-116 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CVS48_RS09995 343b9640113c43a367a2d28f89666755 332 SUPERFAMILY SSF50129 7 156 4.57E-32 T 29-03-2018 IPR011032 GroES-like CVS48_RS18610 5533551304e0739ba0c2369268f9efe9 141 Pfam PF03960 ArsC family 7 114 2.7E-18 T 29-03-2018 IPR006660 Arsenate reductase-like CVS48_RS18610 5533551304e0739ba0c2369268f9efe9 141 Gene3D G3DSA:3.40.30.10 1 141 2.0E-47 T 29-03-2018 CVS48_RS18610 5533551304e0739ba0c2369268f9efe9 141 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 1.4E-45 T 29-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 CVS48_RS18610 5533551304e0739ba0c2369268f9efe9 141 SUPERFAMILY SSF52833 3 138 5.18E-42 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS03675 733546c7f6933468874946c4cbdd422e 492 ProSitePatterns PS00571 Amidases signature. 172 203 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CVS48_RS03675 733546c7f6933468874946c4cbdd422e 492 Pfam PF01425 Amidase 45 474 6.0E-94 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS03675 733546c7f6933468874946c4cbdd422e 492 SUPERFAMILY SSF75304 20 484 1.27E-115 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS03675 733546c7f6933468874946c4cbdd422e 492 Gene3D G3DSA:3.90.1300.10 17 492 5.2E-117 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS27525 03817829e8336a9890db99d50f901218 377 SUPERFAMILY SSF53383 5 376 2.33E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS27525 03817829e8336a9890db99d50f901218 377 Gene3D G3DSA:3.40.640.10 17 274 4.8E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS27525 03817829e8336a9890db99d50f901218 377 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 204 223 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CVS48_RS27525 03817829e8336a9890db99d50f901218 377 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 3 376 48.854 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CVS48_RS27525 03817829e8336a9890db99d50f901218 377 Gene3D G3DSA:3.90.1150.10 275 375 2.9E-35 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS27525 03817829e8336a9890db99d50f901218 377 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 6 376 6.8E-140 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CVS48_RS27525 03817829e8336a9890db99d50f901218 377 Pfam PF00266 Aminotransferase class-V 6 365 8.5E-45 T 29-03-2018 IPR000192 Aminotransferase class V domain CVS48_RS27525 03817829e8336a9890db99d50f901218 377 PIRSF PIRSF000525 1 377 1.9E-139 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CVS48_RS20715 a90dda716d7537f136907908a781f3c5 756 SUPERFAMILY SSF52540 520 534 2.97E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20715 a90dda716d7537f136907908a781f3c5 756 SUPERFAMILY SSF52540 319 393 2.97E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20715 a90dda716d7537f136907908a781f3c5 756 SUPERFAMILY SSF52540 195 255 2.97E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20715 a90dda716d7537f136907908a781f3c5 756 SUPERFAMILY SSF52540 563 738 2.97E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20715 a90dda716d7537f136907908a781f3c5 756 Gene3D G3DSA:3.40.50.300 568 746 5.7E-6 T 29-03-2018 CVS48_RS20715 a90dda716d7537f136907908a781f3c5 756 Gene3D G3DSA:3.40.50.300 181 559 3.2E-18 T 29-03-2018 CVS48_RS20715 a90dda716d7537f136907908a781f3c5 756 Pfam PF06733 DEAD_2 272 391 1.2E-11 T 29-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 CVS48_RS20715 a90dda716d7537f136907908a781f3c5 756 SMART SM00491 605 742 5.7E-11 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CVS48_RS20715 a90dda716d7537f136907908a781f3c5 756 Pfam PF13307 Helicase C-terminal domain 592 754 4.2E-30 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.979 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 SUPERFAMILY SSF48150 3 208 2.67E-73 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 SMART SM00525 186 206 5.1E-4 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 167 2.0E-20 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 SMART SM00478 38 185 3.6E-57 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 PIRSF PIRSF001435 1 211 1.3E-53 T 29-03-2018 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 TIGRFAM TIGR01083 nth: endonuclease III 5 194 2.7E-85 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 Gene3D G3DSA:1.10.1670.10 118 211 3.0E-31 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 Gene3D G3DSA:1.10.340.30 9 117 1.2E-26 T 29-03-2018 CVS48_RS28460 1eaafa8cfc4dcdbf3202075362b440da 211 Pfam PF00633 Helix-hairpin-helix motif 100 127 6.3E-9 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CVS48_RS07290 9d885a11dc9596e6784b3069f76e65f3 334 Pfam PF00589 Phage integrase family 129 316 1.4E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS07290 9d885a11dc9596e6784b3069f76e65f3 334 Gene3D G3DSA:1.10.443.10 131 324 8.1E-43 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS07290 9d885a11dc9596e6784b3069f76e65f3 334 Gene3D G3DSA:1.10.150.130 17 130 7.0E-23 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CVS48_RS07290 9d885a11dc9596e6784b3069f76e65f3 334 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 26 331 6.2E-107 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CVS48_RS07290 9d885a11dc9596e6784b3069f76e65f3 334 SUPERFAMILY SSF56349 24 324 4.71E-49 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS07290 9d885a11dc9596e6784b3069f76e65f3 334 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 22 330 55.684 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CVS48_RS07290 9d885a11dc9596e6784b3069f76e65f3 334 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 26 101 2.0E-16 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 7.7E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 7.7E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 7.7E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 SMART SM00344 4 110 2.2E-30 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 Pfam PF01037 Lrp/AsnC ligand binding domain 86 138 1.8E-12 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 SUPERFAMILY SSF54909 66 148 2.15E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 Pfam PF13404 AsnC-type helix-turn-helix domain 4 45 2.3E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 SUPERFAMILY SSF46785 4 63 8.02E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 Gene3D G3DSA:3.30.70.920 57 148 1.8E-16 T 29-03-2018 CVS48_RS19180 998213fd32b7f14724be871ed543c18a 155 Gene3D G3DSA:1.10.10.10 1 55 7.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12860 68a8bc246996fa694e1422eb8e261778 163 Gene3D G3DSA:3.90.1170.40 1 152 1.3E-48 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CVS48_RS12860 68a8bc246996fa694e1422eb8e261778 163 SUPERFAMILY SSF54690 4 152 6.54E-45 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CVS48_RS12860 68a8bc246996fa694e1422eb8e261778 163 Pfam PF02391 MoaE protein 7 122 2.9E-32 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CVS48_RS10700 1e491df45b1d6ed6626741c3f55e0afa 643 Gene3D G3DSA:3.40.50.620 230 635 1.4E-80 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS10700 1e491df45b1d6ed6626741c3f55e0afa 643 SUPERFAMILY SSF52402 247 396 2.39E-92 T 29-03-2018 CVS48_RS10700 1e491df45b1d6ed6626741c3f55e0afa 643 SUPERFAMILY SSF52402 483 623 2.39E-92 T 29-03-2018 CVS48_RS10700 1e491df45b1d6ed6626741c3f55e0afa 643 SUPERFAMILY SSF56235 1 224 9.44E-60 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS10700 1e491df45b1d6ed6626741c3f55e0afa 643 Pfam PF13537 Glutamine amidotransferase domain 47 169 1.2E-42 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CVS48_RS10700 1e491df45b1d6ed6626741c3f55e0afa 643 Gene3D G3DSA:3.60.20.10 1 229 1.3E-53 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS10700 1e491df45b1d6ed6626741c3f55e0afa 643 Pfam PF00733 Asparagine synthase 256 627 1.5E-113 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CVS48_RS10700 1e491df45b1d6ed6626741c3f55e0afa 643 PIRSF PIRSF001589 1 639 1.2E-162 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CVS48_RS10700 1e491df45b1d6ed6626741c3f55e0afa 643 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 563 2.6E-139 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CVS48_RS18170 72a8669bb209d3ef208d12843d913ab4 140 Pfam PF07681 DoxX 22 97 1.9E-13 T 29-03-2018 IPR032808 DoxX family CVS48_RS03455 78d23433dc39f6e0c22e112da2f87595 651 Gene3D G3DSA:3.60.40.10 392 651 4.7E-22 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CVS48_RS03455 78d23433dc39f6e0c22e112da2f87595 651 Pfam PF00672 HAMP domain 325 373 1.7E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS03455 78d23433dc39f6e0c22e112da2f87595 651 SMART SM00331 427 650 1.2E-4 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CVS48_RS03455 78d23433dc39f6e0c22e112da2f87595 651 SUPERFAMILY SSF158472 325 374 2.62E-11 T 29-03-2018 CVS48_RS03455 78d23433dc39f6e0c22e112da2f87595 651 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 454 650 3.0E-22 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CVS48_RS03455 78d23433dc39f6e0c22e112da2f87595 651 SMART SM00304 325 377 8.6E-17 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS03455 78d23433dc39f6e0c22e112da2f87595 651 Gene3D G3DSA:3.30.450.20 153 291 2.2E-8 T 29-03-2018 CVS48_RS06315 3f40a61667aabe52bb823abf508b1e08 233 Gene3D G3DSA:1.10.10.10 124 233 5.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06315 3f40a61667aabe52bb823abf508b1e08 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 230 9.4E-10 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS06315 3f40a61667aabe52bb823abf508b1e08 233 SMART SM00448 4 114 0.0056 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS06315 3f40a61667aabe52bb823abf508b1e08 233 SUPERFAMILY SSF52172 1 126 2.42E-14 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS06315 3f40a61667aabe52bb823abf508b1e08 233 Pfam PF00072 Response regulator receiver domain 12 111 6.7E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS06315 3f40a61667aabe52bb823abf508b1e08 233 SMART SM00862 152 230 3.6E-10 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS06315 3f40a61667aabe52bb823abf508b1e08 233 Gene3D G3DSA:3.40.50.2300 1 123 4.3E-13 T 29-03-2018 CVS48_RS06315 3f40a61667aabe52bb823abf508b1e08 233 SUPERFAMILY SSF46894 139 231 1.53E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Pfam PF10385 RNA polymerase beta subunit external 1 domain 597 662 1.2E-23 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Pfam PF04563 RNA polymerase beta subunit 27 506 7.8E-36 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Pfam PF04561 RNA polymerase Rpb2, domain 2 355 460 2.6E-16 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Pfam PF04561 RNA polymerase Rpb2, domain 2 155 227 7.8E-5 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Pfam PF00562 RNA polymerase Rpb2, domain 6 725 1292 2.5E-157 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Gene3D G3DSA:2.40.50.100 721 801 1.1E-27 T 29-03-2018 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1370 12.204 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Gene3D G3DSA:2.40.270.10 1065 1270 3.4E-77 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Pfam PF04565 RNA polymerase Rpb2, domain 3 519 586 1.2E-31 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Pfam PF04560 RNA polymerase Rpb2, domain 7 1294 1368 7.5E-26 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Gene3D G3DSA:3.90.1100.10 652 719 1.3E-15 T 29-03-2018 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Gene3D G3DSA:3.90.1100.10 435 651 2.2E-81 T 29-03-2018 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 SUPERFAMILY SSF64484 348 945 0.0 T 29-03-2018 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 SUPERFAMILY SSF64484 1058 1368 0.0 T 29-03-2018 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 SUPERFAMILY SSF64484 12 230 0.0 T 29-03-2018 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Gene3D G3DSA:2.40.50.150 835 1064 3.1E-52 T 29-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Gene3D G3DSA:3.90.1110.10 152 434 6.1E-64 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1366 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06275 441bf9a8d19a153299c2ca25b2e41328 1370 Gene3D G3DSA:3.90.1800.10 1295 1362 4.9E-12 T 29-03-2018 CVS48_RS23905 3d146f5a44cacc3e47d12a4e5870741b 330 Pfam PF03812 2-keto-3-deoxygluconate permease 1 303 1.6E-106 T 29-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 CVS48_RS23905 3d146f5a44cacc3e47d12a4e5870741b 330 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 20 303 7.0E-103 T 29-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 Gene3D G3DSA:3.30.70.1430 38 140 6.9E-27 T 29-03-2018 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 Gene3D G3DSA:3.30.2090.10 182 277 2.0E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 SUPERFAMILY SSF82866 805 1027 1.28E-44 T 29-03-2018 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 Pfam PF00873 AcrB/AcrD/AcrF family 1 1025 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 SUPERFAMILY SSF82693 137 184 3.49E-24 T 29-03-2018 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 SUPERFAMILY SSF82693 276 332 3.49E-24 T 29-03-2018 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 SUPERFAMILY SSF82693 38 131 9.77E-25 T 29-03-2018 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 Gene3D G3DSA:3.30.2090.10 721 809 9.4E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1036 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 SUPERFAMILY SSF82714 185 273 3.01E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 3.4E-102 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 3.4E-102 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 3.4E-102 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 3.4E-102 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 3.4E-102 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 3.4E-102 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 3.4E-102 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 3.4E-102 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 PRINTS PR00702 Acriflavin resistance protein family signature 555 572 3.4E-102 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 SUPERFAMILY SSF82693 568 671 1.39E-29 T 29-03-2018 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 SUPERFAMILY SSF82866 298 499 4.05E-52 T 29-03-2018 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 SUPERFAMILY SSF82714 722 807 1.11E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 Gene3D G3DSA:3.30.70.1430 570 668 6.8E-21 T 29-03-2018 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 Gene3D G3DSA:1.20.1640.10 289 512 1.1E-50 T 29-03-2018 CVS48_RS20300 b932d93cbacbdd76ea6c273ff0011cd3 1049 Gene3D G3DSA:1.20.1640.10 827 1027 1.3E-35 T 29-03-2018 CVS48_RS14150 3548d507b4ed62764e7f39f6c6917b8e 322 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14 188 4.2E-47 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS14150 3548d507b4ed62764e7f39f6c6917b8e 322 SUPERFAMILY SSF48179 194 264 1.02E-14 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS14150 3548d507b4ed62764e7f39f6c6917b8e 322 Gene3D G3DSA:3.40.50.720 1 191 7.1E-42 T 29-03-2018 CVS48_RS14150 3548d507b4ed62764e7f39f6c6917b8e 322 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 191 215 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS14150 3548d507b4ed62764e7f39f6c6917b8e 322 Gene3D G3DSA:1.10.1040.10 194 322 2.2E-19 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS14150 3548d507b4ed62764e7f39f6c6917b8e 322 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 194 258 2.9E-16 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS14150 3548d507b4ed62764e7f39f6c6917b8e 322 SUPERFAMILY SSF51735 13 191 7.99E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS02640 31e0348d756e77f1b34a6a3cb9eb5b08 309 Gene3D G3DSA:3.40.50.720 107 277 6.4E-46 T 29-03-2018 CVS48_RS02640 31e0348d756e77f1b34a6a3cb9eb5b08 309 SUPERFAMILY SSF51735 95 275 6.52E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS02640 31e0348d756e77f1b34a6a3cb9eb5b08 309 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 274 3.9E-46 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS02640 31e0348d756e77f1b34a6a3cb9eb5b08 309 Gene3D G3DSA:3.40.50.720 3 106 8.6E-5 T 29-03-2018 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 Gene3D G3DSA:3.40.50.80 106 243 2.9E-26 T 29-03-2018 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 Gene3D G3DSA:3.10.20.30 244 361 4.1E-29 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 Pfam PF00970 Oxidoreductase FAD-binding domain 9 104 7.5E-13 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 SUPERFAMILY SSF63380 4 106 2.07E-27 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 117 136 4.3E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 142 151 4.3E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 56 63 4.3E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 154 165 4.3E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 5 358 1.7E-141 T 29-03-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 SUPERFAMILY SSF54292 236 356 1.35E-28 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 275 348 2.4E-15 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 306 314 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 Gene3D G3DSA:2.40.30.10 1 103 4.3E-23 T 29-03-2018 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 SUPERFAMILY SSF52343 95 243 4.85E-32 T 29-03-2018 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 Pfam PF00175 Oxidoreductase NAD-binding domain 120 226 8.3E-17 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 PRINTS PR00406 Cytochrome B5 reductase signature 117 136 2.7E-8 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 PRINTS PR00406 Cytochrome B5 reductase signature 154 165 2.7E-8 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 PRINTS PR00406 Cytochrome B5 reductase signature 92 106 2.7E-8 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CVS48_RS27290 47ea213bd5ebd9a6b03714b1cea170c6 361 PRINTS PR00406 Cytochrome B5 reductase signature 213 221 2.7E-8 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 SUPERFAMILY SSF51735 8 248 1.58E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.3E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.3E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.3E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.3E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.3E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.3E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 2.0E-67 T 29-03-2018 CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 Gene3D G3DSA:3.40.50.720 48 249 6.2E-67 T 29-03-2018 CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 Gene3D G3DSA:3.40.50.720 2 47 2.1E-11 T 29-03-2018 CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 12 247 1.8E-99 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.7E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.7E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.7E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28315 741e1f44f22f64aa27c92086ac35d087 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 192 1.8E-4 T 29-03-2018 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 SUPERFAMILY SSF102886 8 303 1.57E-131 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 PIRSF PIRSF000166 4 303 4.3E-121 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 3 279 52.823 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 168 192 - T 29-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 Pfam PF01218 Coproporphyrinogen III oxidase 9 303 5.6E-127 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 Gene3D G3DSA:3.40.1500.10 4 303 1.4E-133 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 PRINTS PR00073 Coprogen oxidase signature 89 113 1.2E-79 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 PRINTS PR00073 Coprogen oxidase signature 127 149 1.2E-79 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 PRINTS PR00073 Coprogen oxidase signature 236 263 1.2E-79 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 PRINTS PR00073 Coprogen oxidase signature 30 46 1.2E-79 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 PRINTS PR00073 Coprogen oxidase signature 264 290 1.2E-79 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 PRINTS PR00073 Coprogen oxidase signature 47 68 1.2E-79 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS14340 8312db48c09607308aa93d0688c6f45e 303 PRINTS PR00073 Coprogen oxidase signature 164 193 1.2E-79 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CVS48_RS03500 8de5c5c8087419b624a0771b0d8f069f 288 Pfam PF05673 Protein of unknown function (DUF815) 35 286 4.4E-106 T 29-03-2018 IPR008533 Domain of unknown function DUF815 CVS48_RS03500 8de5c5c8087419b624a0771b0d8f069f 288 SUPERFAMILY SSF52540 45 194 1.33E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03500 8de5c5c8087419b624a0771b0d8f069f 288 Gene3D G3DSA:3.40.50.300 68 200 4.3E-13 T 29-03-2018 CVS48_RS06900 6c44666703ddbdd97aa66ade72aeb4aa 161 SUPERFAMILY SSF55781 9 157 3.53E-44 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS06900 6c44666703ddbdd97aa66ade72aeb4aa 161 Pfam PF13185 GAF domain 44 153 1.0E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS06900 6c44666703ddbdd97aa66ade72aeb4aa 161 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 99 116 - T 29-03-2018 IPR000614 Free Met sulfoxide reductase conserved site CVS48_RS06900 6c44666703ddbdd97aa66ade72aeb4aa 161 SMART SM00065 15 161 0.0061 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS06900 6c44666703ddbdd97aa66ade72aeb4aa 161 Gene3D G3DSA:3.30.450.40 4 161 1.1E-28 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 Pfam PF01926 50S ribosome-binding GTPase 222 335 1.7E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 Gene3D G3DSA:1.20.120.430 125 284 1.3E-26 T 29-03-2018 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 SUPERFAMILY SSF116878 374 450 8.24E-48 T 29-03-2018 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 SUPERFAMILY SSF116878 124 223 8.24E-48 T 29-03-2018 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 221 338 1.5E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 Gene3D G3DSA:3.30.1360.120 1 124 3.1E-42 T 29-03-2018 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 450 4.3E-100 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 450 32.678 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 Gene3D G3DSA:1.20.120.430 285 450 2.4E-34 T 29-03-2018 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 123 4.9E-38 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 SUPERFAMILY SSF52540 71 155 6.64E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 SUPERFAMILY SSF52540 191 367 6.64E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06095 f3f33778bff645dcd3a3993da4001cbf 450 Pfam PF12631 MnmE helical domain 126 447 4.5E-55 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 65 2.2E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 Gene3D G3DSA:3.40.190.10 170 252 1.2E-14 T 29-03-2018 CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 SUPERFAMILY SSF53850 91 281 3.69E-28 T 29-03-2018 CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 Gene3D G3DSA:3.40.190.10 93 169 4.5E-14 T 29-03-2018 CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 SUPERFAMILY SSF46785 1 107 2.04E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 Pfam PF03466 LysR substrate binding domain 91 273 5.4E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS26055 e2611769dfabe2eba0b28139810c2362 290 Gene3D G3DSA:1.10.10.10 1 86 8.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28295 973954ed0bf9ebb9b9c58f124705303c 199 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 191 2.2E-95 T 29-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS28295 973954ed0bf9ebb9b9c58f124705303c 199 Pfam PF08281 Sigma-70, region 4 134 182 6.8E-18 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS28295 973954ed0bf9ebb9b9c58f124705303c 199 SUPERFAMILY SSF88946 3 104 1.73E-32 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS28295 973954ed0bf9ebb9b9c58f124705303c 199 Pfam PF04542 Sigma-70 region 2 25 92 7.7E-19 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS28295 973954ed0bf9ebb9b9c58f124705303c 199 Gene3D G3DSA:1.10.1740.10 1 107 7.3E-31 T 29-03-2018 CVS48_RS28295 973954ed0bf9ebb9b9c58f124705303c 199 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS28295 973954ed0bf9ebb9b9c58f124705303c 199 Gene3D G3DSA:1.10.10.10 109 190 7.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28295 973954ed0bf9ebb9b9c58f124705303c 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 187 2.8E-34 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS28295 973954ed0bf9ebb9b9c58f124705303c 199 SUPERFAMILY SSF88659 125 187 1.33E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS26295 02bfb1fff36f8858feef9ef59ab3b468 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 311 1.4E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS26295 02bfb1fff36f8858feef9ef59ab3b468 341 SUPERFAMILY SSF52540 18 266 3.94E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26295 02bfb1fff36f8858feef9ef59ab3b468 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 331 2.0E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS26295 02bfb1fff36f8858feef9ef59ab3b468 341 Pfam PF00005 ABC transporter 38 195 1.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS26295 02bfb1fff36f8858feef9ef59ab3b468 341 Gene3D G3DSA:3.40.50.300 14 340 1.7E-78 T 29-03-2018 CVS48_RS26295 02bfb1fff36f8858feef9ef59ab3b468 341 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS26295 02bfb1fff36f8858feef9ef59ab3b468 341 SMART SM00382 46 253 2.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03610 e34c90076701f760b481a50d00e25530 1203 SUPERFAMILY SSF52518 30 209 8.83E-22 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS03610 e34c90076701f760b481a50d00e25530 1203 SUPERFAMILY SSF53323 744 945 1.57E-31 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CVS48_RS03610 e34c90076701f760b481a50d00e25530 1203 Gene3D G3DSA:3.40.920.10 743 954 2.0E-49 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CVS48_RS03610 e34c90076701f760b481a50d00e25530 1203 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 479 627 3.2E-7 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS03610 e34c90076701f760b481a50d00e25530 1203 Gene3D G3DSA:3.40.50.970 296 666 1.4E-36 T 29-03-2018 CVS48_RS03610 e34c90076701f760b481a50d00e25530 1203 SUPERFAMILY SSF52518 459 642 1.02E-14 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS03610 e34c90076701f760b481a50d00e25530 1203 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 752 939 8.5E-21 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CVS48_RS03610 e34c90076701f760b481a50d00e25530 1203 Gene3D G3DSA:3.40.50.970 25 295 6.7E-24 T 29-03-2018 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 SMART SM00388 154 219 1.6E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 264 371 1.6E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 Gene3D G3DSA:3.40.50.2300 3 130 6.1E-32 T 29-03-2018 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 Gene3D G3DSA:3.30.450.20 131 175 7.2E-5 T 29-03-2018 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 SUPERFAMILY SSF52172 12 152 3.13E-31 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 SUPERFAMILY SSF47384 139 217 2.55E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 218 1.1E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 Gene3D G3DSA:3.30.565.10 179 371 2.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 Pfam PF00072 Response regulator receiver domain 16 127 9.4E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 SMART SM00448 13 128 6.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 SMART SM00387 263 373 4.3E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 SUPERFAMILY SSF55874 209 371 2.88E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 352 1.9E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 328 1.9E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS18110 d11045f2ef49b3e6d8e4b530950459a4 375 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 370 1.9E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 174 4.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 SMART SM00433 34 647 8.3E-187 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 SUPERFAMILY SSF55874 5 219 6.55E-61 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 Gene3D G3DSA:3.30.565.10 18 220 1.2E-60 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 Pfam PF01751 Toprim domain 423 536 8.6E-12 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 3 651 44.521 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 SUPERFAMILY SSF54211 222 397 3.6E-36 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 Pfam PF00204 DNA gyrase B 222 395 2.4E-32 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR00418 DNA topoisomerase II family signature 67 80 2.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR00418 DNA topoisomerase II family signature 113 127 2.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR00418 DNA topoisomerase II family signature 276 289 2.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR00418 DNA topoisomerase II family signature 32 47 2.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR00418 DNA topoisomerase II family signature 424 438 2.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR00418 DNA topoisomerase II family signature 531 543 2.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR00418 DNA topoisomerase II family signature 583 599 2.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR00418 DNA topoisomerase II family signature 511 528 2.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR00418 DNA topoisomerase II family signature 493 509 2.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 Gene3D G3DSA:3.40.50.670 405 650 7.0E-78 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 SMART SM00387 29 177 7.9E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR01098 Topoisomerase IV subunit B signature 372 397 5.7E-40 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR01098 Topoisomerase IV subunit B signature 458 479 5.7E-40 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR01098 Topoisomerase IV subunit B signature 321 336 5.7E-40 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR01098 Topoisomerase IV subunit B signature 196 217 5.7E-40 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR01098 Topoisomerase IV subunit B signature 27 40 5.7E-40 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR01098 Topoisomerase IV subunit B signature 178 195 5.7E-40 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR01098 Topoisomerase IV subunit B signature 304 320 5.7E-40 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 PRINTS PR01098 Topoisomerase IV subunit B signature 348 371 5.7E-40 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 SUPERFAMILY SSF56719 399 644 9.68E-74 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 580 643 1.5E-25 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS14470 ed9f0890c6efd56ef358ffc886a2cc9c 653 Gene3D G3DSA:3.30.230.10 221 401 6.3E-31 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS06065 ad2becdd6a14a9a4bbdc8567e43c7ec6 399 Pfam PF07687 Peptidase dimerisation domain 187 279 6.0E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS06065 ad2becdd6a14a9a4bbdc8567e43c7ec6 399 PIRSF PIRSF005962 1 398 1.9E-123 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS06065 ad2becdd6a14a9a4bbdc8567e43c7ec6 399 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 383 1.6E-110 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS06065 ad2becdd6a14a9a4bbdc8567e43c7ec6 399 Pfam PF01546 Peptidase family M20/M25/M40 73 393 1.4E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS06065 ad2becdd6a14a9a4bbdc8567e43c7ec6 399 Gene3D G3DSA:3.40.630.10 2 217 4.6E-53 T 29-03-2018 CVS48_RS06065 ad2becdd6a14a9a4bbdc8567e43c7ec6 399 Gene3D G3DSA:3.40.630.10 218 399 3.0E-27 T 29-03-2018 CVS48_RS06065 ad2becdd6a14a9a4bbdc8567e43c7ec6 399 SUPERFAMILY SSF53187 299 396 8.0E-90 T 29-03-2018 CVS48_RS06065 ad2becdd6a14a9a4bbdc8567e43c7ec6 399 SUPERFAMILY SSF53187 3 198 8.0E-90 T 29-03-2018 CVS48_RS06065 ad2becdd6a14a9a4bbdc8567e43c7ec6 399 SUPERFAMILY SSF55031 184 297 8.11E-31 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS17825 4a0c42f36f3b779f7d9d673181ad299b 311 Pfam PF03466 LysR substrate binding domain 88 294 1.8E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17825 4a0c42f36f3b779f7d9d673181ad299b 311 Gene3D G3DSA:3.40.190.10 88 175 1.9E-13 T 29-03-2018 CVS48_RS17825 4a0c42f36f3b779f7d9d673181ad299b 311 Gene3D G3DSA:3.40.190.10 176 267 6.1E-23 T 29-03-2018 CVS48_RS17825 4a0c42f36f3b779f7d9d673181ad299b 311 Gene3D G3DSA:1.10.10.10 3 84 1.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17825 4a0c42f36f3b779f7d9d673181ad299b 311 SUPERFAMILY SSF53850 90 299 4.89E-42 T 29-03-2018 CVS48_RS17825 4a0c42f36f3b779f7d9d673181ad299b 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17825 4a0c42f36f3b779f7d9d673181ad299b 311 SUPERFAMILY SSF46785 4 111 3.36E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28735 bc674b3294b256a807b24938f52ec884 264 Pfam PF00149 Calcineurin-like phosphoesterase 3 190 3.1E-16 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS28735 bc674b3294b256a807b24938f52ec884 264 Gene3D G3DSA:3.60.21.10 2 262 5.6E-41 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS28735 bc674b3294b256a807b24938f52ec884 264 SUPERFAMILY SSF56300 1 234 1.57E-54 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS01305 9e2c828c506764a6f6d262334efebd8e 287 SUPERFAMILY SSF55781 82 267 1.05E-46 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS01305 9e2c828c506764a6f6d262334efebd8e 287 SMART SM00346 25 114 5.1E-22 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS01305 9e2c828c506764a6f6d262334efebd8e 287 Pfam PF01614 Bacterial transcriptional regulator 143 262 4.0E-32 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS01305 9e2c828c506764a6f6d262334efebd8e 287 Gene3D G3DSA:3.30.450.40 96 271 1.9E-47 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS01305 9e2c828c506764a6f6d262334efebd8e 287 Pfam PF09339 IclR helix-turn-helix domain 28 77 9.4E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS01305 9e2c828c506764a6f6d262334efebd8e 287 SUPERFAMILY SSF46785 25 96 8.11E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01305 9e2c828c506764a6f6d262334efebd8e 287 Gene3D G3DSA:1.10.10.10 9 85 4.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24545 8b1a8091bbd4cee02d7c3342aa2f302a 454 Pfam PF00772 DnaB-like helicase N terminal domain 7 104 1.0E-22 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CVS48_RS24545 8b1a8091bbd4cee02d7c3342aa2f302a 454 SUPERFAMILY SSF52540 180 423 2.82E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS24545 8b1a8091bbd4cee02d7c3342aa2f302a 454 Pfam PF03796 DnaB-like helicase C terminal domain 180 430 3.2E-78 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CVS48_RS24545 8b1a8091bbd4cee02d7c3342aa2f302a 454 Gene3D G3DSA:1.10.860.10 1 145 7.0E-33 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CVS48_RS24545 8b1a8091bbd4cee02d7c3342aa2f302a 454 SUPERFAMILY SSF48024 6 112 8.5E-24 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CVS48_RS24545 8b1a8091bbd4cee02d7c3342aa2f302a 454 Gene3D G3DSA:3.40.50.300 162 444 4.0E-48 T 29-03-2018 CVS48_RS06365 7b65981fab9507c8a7aee1ddb786a9e6 199 Pfam PF07883 Cupin domain 94 163 5.0E-11 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS06365 7b65981fab9507c8a7aee1ddb786a9e6 199 Gene3D G3DSA:2.60.120.10 33 198 2.8E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS06365 7b65981fab9507c8a7aee1ddb786a9e6 199 SUPERFAMILY SSF51182 32 179 5.35E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS23495 30914db23ba94fd3def4d649090c9e3f 740 Pfam PF07715 TonB-dependent Receptor Plug Domain 81 178 2.1E-14 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS23495 30914db23ba94fd3def4d649090c9e3f 740 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 83 740 4.1E-109 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS23495 30914db23ba94fd3def4d649090c9e3f 740 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 723 740 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS23495 30914db23ba94fd3def4d649090c9e3f 740 Gene3D G3DSA:2.170.130.10 17 195 8.1E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS23495 30914db23ba94fd3def4d649090c9e3f 740 Gene3D G3DSA:2.40.170.20 196 740 4.2E-66 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS23495 30914db23ba94fd3def4d649090c9e3f 740 SUPERFAMILY SSF56935 69 740 1.69E-105 T 29-03-2018 CVS48_RS23495 30914db23ba94fd3def4d649090c9e3f 740 Pfam PF00593 TonB dependent receptor 289 738 7.4E-42 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Gene3D G3DSA:3.40.50.280 773 928 2.5E-54 T 29-03-2018 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Gene3D G3DSA:3.10.196.10 990 1257 1.0E-93 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 SUPERFAMILY SSF51717 368 634 1.83E-86 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 PIRSF PIRSF000381 13 1229 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Gene3D G3DSA:3.20.20.330 12 352 2.7E-111 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 SUPERFAMILY SSF52242 772 926 6.15E-42 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Pfam PF00809 Pterin binding enzyme 371 609 1.6E-57 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 SMART SM01018 676 763 2.2E-42 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 TIGRFAM TIGR02082 metH: methionine synthase 24 1226 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Pfam PF02607 B12 binding domain 678 755 2.9E-25 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Gene3D G3DSA:1.10.1240.10 666 763 3.9E-36 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 970 1241 1.3E-115 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Gene3D G3DSA:3.20.20.20 356 665 4.4E-70 T 29-03-2018 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 SUPERFAMILY SSF56507 934 1256 1.96E-121 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 SUPERFAMILY SSF82282 19 410 6.93E-116 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Pfam PF02310 B12 binding domain 778 872 8.0E-18 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 Pfam PF02574 Homocysteine S-methyltransferase 28 336 1.4E-78 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CVS48_RS03680 7dab6c6c3215d44a73c26eaa0a148dea 1257 SUPERFAMILY SSF47644 671 762 1.12E-26 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Pfam PF00550 Phosphopantetheine attachment site 2415 2479 3.4E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.40.366.10 713 837 7.4E-30 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.30.70.250 668 712 2.6E-13 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.10.129.10 892 1017 3.3E-6 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Pfam PF14765 Polyketide synthase dehydratase 894 1168 2.1E-49 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SMART SM00823 Phosphopantetheine attachment site 2412 2483 2.7E-15 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 379 488 2.7E-17 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SMART SM00829 1790 2105 3.2E-176 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.40.47.10 1 262 3.2E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.90.180.10 2047 2109 0.0011 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.40.50.720 2124 2382 4.5E-50 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF50129 1789 1932 1.34E-25 T 29-03-2018 IPR011032 GroES-like CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2438 2453 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.40.366.10 526 667 3.1E-37 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF52151 531 657 1.31E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF52151 723 819 1.31E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2131 2311 3.6E-57 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 163 179 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:1.10.1200.10 2406 2517 1.1E-17 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Pfam PF08659 KR domain 2131 2309 3.0E-63 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF51735 1894 2054 3.62E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.90.180.10 1781 1924 7.0E-35 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF51735 1571 1768 7.87E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 248 5.5E-83 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SMART SM01294 2413 2479 1.2E-4 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 533 831 7.2E-93 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF51735 2129 2317 1.11E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.40.50.720 1925 2045 1.1E-21 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF47336 2411 2502 6.02E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF53335 1392 1538 8.91E-8 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.40.47.10 265 425 1.6E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 258 375 3.7E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Pfam PF00698 Acyl transferase domain 532 821 4.3E-66 T 29-03-2018 IPR014043 Acyl transferase CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF55048 657 721 3.27E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1808 1870 5.9E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SMART SM00825 Beta-ketoacyl synthase 5 427 6.7E-188 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Pfam PF00107 Zinc-binding dehydrogenase 1934 2049 7.1E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF53901 402 423 3.92E-97 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SUPERFAMILY SSF53901 3 371 3.92E-97 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.40.50.720 1585 1776 0.0018 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 Gene3D G3DSA:3.40.50.150 1374 1584 1.2E-4 T 29-03-2018 CVS48_RS19335 f5f1f4a8bbfcfaac0a081849cad7f50d 2535 SMART SM00826 894 1052 7.5E-35 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CVS48_RS01900 12f0135ec9f1b264b98724906bf5931c 324 PIRSF PIRSF017082 1 324 9.7E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01900 12f0135ec9f1b264b98724906bf5931c 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 3.1E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01900 12f0135ec9f1b264b98724906bf5931c 324 Gene3D G3DSA:3.40.190.10 34 293 2.6E-10 T 29-03-2018 CVS48_RS01900 12f0135ec9f1b264b98724906bf5931c 324 SUPERFAMILY SSF53850 100 286 1.14E-10 T 29-03-2018 CVS48_RS05700 edbf6bd68fbb4f5c6d47e66ec3b1eecc 320 Gene3D G3DSA:3.40.190.10 160 319 5.3E-38 T 29-03-2018 CVS48_RS05700 edbf6bd68fbb4f5c6d47e66ec3b1eecc 320 SUPERFAMILY SSF53850 26 319 4.71E-73 T 29-03-2018 CVS48_RS05700 edbf6bd68fbb4f5c6d47e66ec3b1eecc 320 Pfam PF16868 NMT1-like family 31 317 9.6E-87 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CVS48_RS05700 edbf6bd68fbb4f5c6d47e66ec3b1eecc 320 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 4 317 1.1E-102 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CVS48_RS05700 edbf6bd68fbb4f5c6d47e66ec3b1eecc 320 Gene3D G3DSA:3.40.190.10 23 155 6.7E-25 T 29-03-2018 CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 90 2.8E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 SMART SM00345 31 90 1.0E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 Gene3D G3DSA:1.10.10.10 2 92 4.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 SUPERFAMILY SSF46785 25 94 7.94E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 Pfam PF07702 UTRA domain 115 253 1.7E-36 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 80 3.9E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 64 3.9E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 SMART SM00866 111 253 1.6E-37 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 Gene3D G3DSA:3.40.1410.10 98 258 1.3E-37 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS27915 629d9b8011c0440822495d718ed0b26a 259 SUPERFAMILY SSF64288 80 257 1.51E-42 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 Gene3D G3DSA:3.40.50.720 5 52 2.4E-4 T 29-03-2018 CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 Gene3D G3DSA:3.40.50.720 53 253 8.0E-64 T 29-03-2018 CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 251 2.2E-61 T 29-03-2018 CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 5.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 9.1E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.1E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 9.1E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26770 2c63917191307dbe04e1b3158d30b097 253 SUPERFAMILY SSF51735 10 252 9.16E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23505 4ff9b519cf7170e928381d4b002ed42b 303 SUPERFAMILY SSF46785 6 116 1.18E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23505 4ff9b519cf7170e928381d4b002ed42b 303 Gene3D G3DSA:1.10.10.10 1 85 2.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23505 4ff9b519cf7170e928381d4b002ed42b 303 SUPERFAMILY SSF53850 94 300 7.96E-39 T 29-03-2018 CVS48_RS23505 4ff9b519cf7170e928381d4b002ed42b 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 2.0E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23505 4ff9b519cf7170e928381d4b002ed42b 303 Gene3D G3DSA:3.40.190.10 184 269 1.5E-20 T 29-03-2018 CVS48_RS23505 4ff9b519cf7170e928381d4b002ed42b 303 Pfam PF03466 LysR substrate binding domain 92 298 7.2E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS23505 4ff9b519cf7170e928381d4b002ed42b 303 Gene3D G3DSA:3.40.190.10 96 183 5.0E-13 T 29-03-2018 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 472 5.1E-163 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 Pfam PF00571 CBS domain 95 138 1.0E-9 T 29-03-2018 IPR000644 CBS domain CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 Pfam PF00571 CBS domain 149 201 7.8E-5 T 29-03-2018 IPR000644 CBS domain CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 SUPERFAMILY SSF51412 215 476 1.7E-125 T 29-03-2018 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 SUPERFAMILY SSF51412 2 89 1.7E-125 T 29-03-2018 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 SUPERFAMILY SSF54631 94 201 7.44E-28 T 29-03-2018 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 453 4.1E-190 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 PIRSF PIRSF000130 1 486 4.1E-205 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 SMART SM01240 6 472 0.0 T 29-03-2018 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 Gene3D G3DSA:3.20.20.70 1 483 1.3E-115 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 SMART SM00116 156 204 2.0E-6 T 29-03-2018 IPR000644 CBS domain CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 SMART SM00116 95 142 3.6E-11 T 29-03-2018 IPR000644 CBS domain CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CVS48_RS20935 4008d25a0995d61d006834e5bf61a24c 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 485 86.877 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CVS48_RS16245 a00f7dae8f3349bb2d4bc3c2668cdeb1 504 SUPERFAMILY SSF53850 23 501 2.17E-129 T 29-03-2018 CVS48_RS16245 a00f7dae8f3349bb2d4bc3c2668cdeb1 504 Gene3D G3DSA:3.90.76.10 32 175 2.4E-28 T 29-03-2018 CVS48_RS16245 a00f7dae8f3349bb2d4bc3c2668cdeb1 504 Gene3D G3DSA:3.10.105.10 274 474 9.6E-52 T 29-03-2018 CVS48_RS16245 a00f7dae8f3349bb2d4bc3c2668cdeb1 504 Gene3D G3DSA:3.40.190.10 176 273 1.2E-23 T 29-03-2018 CVS48_RS16245 a00f7dae8f3349bb2d4bc3c2668cdeb1 504 PIRSF PIRSF002741 15 503 4.2E-102 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS16245 a00f7dae8f3349bb2d4bc3c2668cdeb1 504 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 66 422 1.7E-81 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS11760 89aedf0784c6aee9d4a41cc23df4570f 275 SUPERFAMILY SSF53474 3 274 3.16E-65 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11760 89aedf0784c6aee9d4a41cc23df4570f 275 PRINTS PR00412 Epoxide hydrolase signature 216 232 1.5E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS11760 89aedf0784c6aee9d4a41cc23df4570f 275 PRINTS PR00412 Epoxide hydrolase signature 29 47 1.5E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS11760 89aedf0784c6aee9d4a41cc23df4570f 275 PRINTS PR00412 Epoxide hydrolase signature 49 64 1.5E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS11760 89aedf0784c6aee9d4a41cc23df4570f 275 Gene3D G3DSA:3.40.50.1820 3 275 3.2E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11760 89aedf0784c6aee9d4a41cc23df4570f 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 2.2E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11760 89aedf0784c6aee9d4a41cc23df4570f 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 2.2E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11760 89aedf0784c6aee9d4a41cc23df4570f 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 2.2E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11760 89aedf0784c6aee9d4a41cc23df4570f 275 Pfam PF00561 alpha/beta hydrolase fold 23 255 1.3E-25 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 Gene3D G3DSA:2.60.260.20 221 297 2.6E-17 T 29-03-2018 CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 Gene3D G3DSA:1.20.5.460 298 317 8.5E-4 T 29-03-2018 CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 Pfam PF01556 DnaJ C terminal domain 140 292 3.7E-31 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 PRINTS PR00625 DnaJ domain signature 61 80 2.6E-21 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 PRINTS PR00625 DnaJ domain signature 41 61 2.6E-21 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 PRINTS PR00625 DnaJ domain signature 7 25 2.6E-21 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 PRINTS PR00625 DnaJ domain signature 25 40 2.6E-21 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 SUPERFAMILY SSF49493 221 301 1.7E-17 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 Gene3D G3DSA:2.60.260.20 136 216 2.0E-20 T 29-03-2018 CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 SUPERFAMILY SSF49493 131 229 1.96E-21 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 SMART SM00271 4 61 3.8E-27 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 SUPERFAMILY SSF46565 1 72 1.03E-28 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 Gene3D G3DSA:1.10.287.110 1 122 4.4E-29 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS13185 ea61b271cdf8b3653313c4ba81bd2904 320 Pfam PF00226 DnaJ domain 5 66 6.5E-23 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS15545 89030691f92238b5dcdf6040f142b72e 209 Gene3D G3DSA:1.20.1050.10 97 203 1.5E-22 T 29-03-2018 CVS48_RS15545 89030691f92238b5dcdf6040f142b72e 209 Pfam PF00043 Glutathione S-transferase, C-terminal domain 127 194 9.4E-10 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS15545 89030691f92238b5dcdf6040f142b72e 209 SUPERFAMILY SSF47616 76 199 2.05E-28 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS15545 89030691f92238b5dcdf6040f142b72e 209 Gene3D G3DSA:3.40.30.10 1 96 4.6E-31 T 29-03-2018 CVS48_RS15545 89030691f92238b5dcdf6040f142b72e 209 SUPERFAMILY SSF52833 2 88 3.18E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS15545 89030691f92238b5dcdf6040f142b72e 209 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 78 1.4E-13 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS08980 2df189fb505bc4ff79f2754873d58ccb 339 Gene3D G3DSA:3.40.190.10 140 249 3.3E-8 T 29-03-2018 CVS48_RS08980 2df189fb505bc4ff79f2754873d58ccb 339 PIRSF PIRSF017082 8 339 1.5E-68 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS08980 2df189fb505bc4ff79f2754873d58ccb 339 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 335 1.8E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS08980 2df189fb505bc4ff79f2754873d58ccb 339 SUPERFAMILY SSF53850 131 298 1.68E-10 T 29-03-2018 CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 Gene3D G3DSA:1.10.8.60 176 270 2.0E-19 T 29-03-2018 CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 215 224 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 SUPERFAMILY SSF52540 2 235 1.46E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 Pfam PF02954 Bacterial regulatory protein, Fis family 266 304 3.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 89 104 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 Pfam PF00158 Sigma-54 interaction domain 4 169 3.0E-60 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 Gene3D G3DSA:3.40.50.300 1 175 1.6E-25 T 29-03-2018 CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 SMART SM00382 23 166 9.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 SUPERFAMILY SSF46689 215 306 6.57E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 Gene3D G3DSA:1.10.10.60 271 309 9.9E-11 T 29-03-2018 CVS48_RS19075 876bc376204ece6b51e8fc6925da64c1 314 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 27 40 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CVS48_RS15645 443671c842440f5471f3dc5c18794951 264 Gene3D G3DSA:3.90.226.10 7 219 9.5E-61 T 29-03-2018 CVS48_RS15645 443671c842440f5471f3dc5c18794951 264 Gene3D G3DSA:1.10.12.10 220 264 3.6E-15 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS15645 443671c842440f5471f3dc5c18794951 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS15645 443671c842440f5471f3dc5c18794951 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 261 1.3E-57 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS15645 443671c842440f5471f3dc5c18794951 264 SUPERFAMILY SSF52096 6 261 8.07E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 SMART SM00895 82 204 1.0E-12 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.8E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.8E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 Pfam PF07729 FCD domain 82 203 5.4E-14 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 Gene3D G3DSA:1.20.120.530 68 218 1.1E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 SUPERFAMILY SSF46785 5 92 6.67E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 Gene3D G3DSA:1.10.10.10 2 67 7.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 SUPERFAMILY SSF48008 79 211 9.42E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 SMART SM00345 14 72 7.1E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18465 6c8e04e9df947d75370d60a93d3979ae 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 9.8E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS12530 b43aafbe723d2eee78c8405174fdad9b 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 120 3.7E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS12530 b43aafbe723d2eee78c8405174fdad9b 144 SUPERFAMILY SSF54593 12 128 4.4E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS12530 b43aafbe723d2eee78c8405174fdad9b 144 PIRSF PIRSF039020 7 127 5.9E-45 T 29-03-2018 IPR026275 Glyoxalase/dioxygenase/EhpR CVS48_RS12530 b43aafbe723d2eee78c8405174fdad9b 144 Gene3D G3DSA:3.10.180.10 8 125 9.0E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS07920 c1baa580490c8465fe5d242cb87ca57f 183 Pfam PF00210 Ferritin-like domain 48 183 1.2E-30 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CVS48_RS07920 c1baa580490c8465fe5d242cb87ca57f 183 Gene3D G3DSA:1.20.1260.10 20 183 4.6E-46 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS07920 c1baa580490c8465fe5d242cb87ca57f 183 SUPERFAMILY SSF47240 40 183 8.84E-41 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS07920 c1baa580490c8465fe5d242cb87ca57f 183 PIRSF PIRSF018063 22 183 2.6E-61 T 29-03-2018 IPR014490 DNA-binding protein from starved cells-like CVS48_RS07920 c1baa580490c8465fe5d242cb87ca57f 183 PRINTS PR00601 Bacterioferritin signature 173 183 2.3E-5 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS07920 c1baa580490c8465fe5d242cb87ca57f 183 PRINTS PR00601 Bacterioferritin signature 42 61 2.3E-5 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS07920 c1baa580490c8465fe5d242cb87ca57f 183 PRINTS PR00601 Bacterioferritin signature 83 103 2.3E-5 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS00685 8a40ace4213f0e35b73fea2474100228 132 Gene3D G3DSA:1.20.1070.10 11 104 3.9E-4 T 29-03-2018 CVS48_RS00685 8a40ace4213f0e35b73fea2474100228 132 Pfam PF11990 Protein of unknown function (DUF3487) 12 130 3.7E-42 T 29-03-2018 IPR021877 Protein of unknown function DUF3487 CVS48_RS00685 8a40ace4213f0e35b73fea2474100228 132 TIGRFAM TIGR03750 conj_TIGR03750: conjugative transfer region protein, TIGR03750 family 14 129 3.2E-43 T 29-03-2018 IPR021877 Protein of unknown function DUF3487 CVS48_RS06550 d3b872462a512256099bb9e49c928543 37 Pfam PF00444 Ribosomal protein L36 1 37 8.5E-18 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06550 d3b872462a512256099bb9e49c928543 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 1.0E-9 T 29-03-2018 CVS48_RS06550 d3b872462a512256099bb9e49c928543 37 SUPERFAMILY SSF57840 1 37 1.7E-16 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06550 d3b872462a512256099bb9e49c928543 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 6.9E-21 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06550 d3b872462a512256099bb9e49c928543 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06550 d3b872462a512256099bb9e49c928543 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.047 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS05685 fd749a21d4d46bf61508ab30f9c2e7a5 218 Gene3D G3DSA:1.10.3720.10 4 218 1.2E-35 T 29-03-2018 CVS48_RS05685 fd749a21d4d46bf61508ab30f9c2e7a5 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 212 1.9E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05685 fd749a21d4d46bf61508ab30f9c2e7a5 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 3.2E-27 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS05685 fd749a21d4d46bf61508ab30f9c2e7a5 218 SUPERFAMILY SSF161098 13 207 1.06E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27485 fc3c5c9379147c4557fc14a6e603b39b 104 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 84 6.5E-16 T 29-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CVS48_RS13925 8c068f10be9572087482b819eccac371 298 Gene3D G3DSA:3.40.190.10 185 268 2.4E-17 T 29-03-2018 CVS48_RS13925 8c068f10be9572087482b819eccac371 298 SUPERFAMILY SSF46785 5 115 2.88E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13925 8c068f10be9572087482b819eccac371 298 Gene3D G3DSA:1.10.10.10 1 86 2.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13925 8c068f10be9572087482b819eccac371 298 Pfam PF03466 LysR substrate binding domain 92 295 2.4E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS13925 8c068f10be9572087482b819eccac371 298 Gene3D G3DSA:3.40.190.10 87 184 7.1E-25 T 29-03-2018 CVS48_RS13925 8c068f10be9572087482b819eccac371 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 7.6E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13925 8c068f10be9572087482b819eccac371 298 SUPERFAMILY SSF53850 92 295 6.52E-38 T 29-03-2018 CVS48_RS01890 2ecbe2da2da31055b8fedf5245ee99be 390 Gene3D G3DSA:3.40.47.10 147 377 1.6E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01890 2ecbe2da2da31055b8fedf5245ee99be 390 Gene3D G3DSA:3.40.47.10 19 133 1.2E-5 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01890 2ecbe2da2da31055b8fedf5245ee99be 390 SUPERFAMILY SSF53901 184 334 6.18E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01890 2ecbe2da2da31055b8fedf5245ee99be 390 SUPERFAMILY SSF53901 30 119 6.18E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01890 2ecbe2da2da31055b8fedf5245ee99be 390 PIRSF PIRSF000429 7 383 5.8E-31 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS01890 2ecbe2da2da31055b8fedf5245ee99be 390 Pfam PF02803 Thiolase, C-terminal domain 261 365 3.0E-7 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS01890 2ecbe2da2da31055b8fedf5245ee99be 390 SUPERFAMILY SSF53901 235 376 3.84E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS05585 dc04000b2674f9ca310999cc2e60ce17 134 Gene3D G3DSA:3.10.180.10 3 134 3.4E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS05585 dc04000b2674f9ca310999cc2e60ce17 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 128 1.2E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS05585 dc04000b2674f9ca310999cc2e60ce17 134 SUPERFAMILY SSF54593 3 132 2.82E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 SUPERFAMILY SSF46785 4 110 3.01E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 Pfam PF03466 LysR substrate binding domain 90 257 5.2E-25 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.8E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 Gene3D G3DSA:3.40.190.10 92 180 3.6E-12 T 29-03-2018 CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 Gene3D G3DSA:3.40.190.10 181 262 1.1E-11 T 29-03-2018 CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 Gene3D G3DSA:1.10.10.10 1 88 2.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 SUPERFAMILY SSF53850 84 266 1.44E-22 T 29-03-2018 CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS27135 ce45862f7b2bdf6c4ce7565315daf57b 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23100 7e3c0f8cf4d65c6a7a701714f19cd855 307 Gene3D G3DSA:3.40.50.300 1 254 1.1E-64 T 29-03-2018 CVS48_RS23100 7e3c0f8cf4d65c6a7a701714f19cd855 307 Pfam PF00005 ABC transporter 21 163 2.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS23100 7e3c0f8cf4d65c6a7a701714f19cd855 307 SMART SM00382 30 211 6.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS23100 7e3c0f8cf4d65c6a7a701714f19cd855 307 SUPERFAMILY SSF52540 2 227 3.69E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23100 7e3c0f8cf4d65c6a7a701714f19cd855 307 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS11435 50f652ade1a6040d40888d13c655ed9b 330 SUPERFAMILY SSF53850 107 292 4.73E-14 T 29-03-2018 CVS48_RS11435 50f652ade1a6040d40888d13c655ed9b 330 PIRSF PIRSF017082 3 330 2.4E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11435 50f652ade1a6040d40888d13c655ed9b 330 Gene3D G3DSA:3.40.190.10 129 241 3.0E-14 T 29-03-2018 CVS48_RS11435 50f652ade1a6040d40888d13c655ed9b 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 325 1.7E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13505 77aa2b71bc2746ddd7a43b3cb42f357b 293 Gene3D G3DSA:1.10.3470.10 2 285 2.3E-42 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS13505 77aa2b71bc2746ddd7a43b3cb42f357b 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 282 3.4E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS14510 488c1ff1c40a6e9baacada36c2b735c2 183 Pfam PF01047 MarR family 41 99 8.7E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14510 488c1ff1c40a6e9baacada36c2b735c2 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 1.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14510 488c1ff1c40a6e9baacada36c2b735c2 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14510 488c1ff1c40a6e9baacada36c2b735c2 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14510 488c1ff1c40a6e9baacada36c2b735c2 183 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CVS48_RS14510 488c1ff1c40a6e9baacada36c2b735c2 183 Gene3D G3DSA:1.10.10.10 4 152 2.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14510 488c1ff1c40a6e9baacada36c2b735c2 183 SMART SM00347 34 134 4.2E-25 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS14510 488c1ff1c40a6e9baacada36c2b735c2 183 SUPERFAMILY SSF46785 11 149 8.59E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25950 fb49e3080d0f35731f4e3413c4c3b62a 409 Gene3D G3DSA:3.40.50.2300 21 197 1.4E-27 T 29-03-2018 CVS48_RS25950 fb49e3080d0f35731f4e3413c4c3b62a 409 SUPERFAMILY SSF53822 36 391 3.36E-84 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS25950 fb49e3080d0f35731f4e3413c4c3b62a 409 Gene3D G3DSA:3.40.50.2300 198 368 1.4E-23 T 29-03-2018 CVS48_RS25950 fb49e3080d0f35731f4e3413c4c3b62a 409 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 293 306 1.8E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS25950 fb49e3080d0f35731f4e3413c4c3b62a 409 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 58 74 1.8E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS25950 fb49e3080d0f35731f4e3413c4c3b62a 409 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 77 95 1.8E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS25950 fb49e3080d0f35731f4e3413c4c3b62a 409 Pfam PF13458 Periplasmic binding protein 37 373 1.9E-71 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS27300 0925540bef6708fe52f4c11975ffbf83 254 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 12 254 3.2E-85 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CVS48_RS27300 0925540bef6708fe52f4c11975ffbf83 254 Gene3D G3DSA:1.20.1260.10 1 254 1.1E-73 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS27300 0925540bef6708fe52f4c11975ffbf83 254 PIRSF PIRSF037834 1 254 6.6E-98 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CVS48_RS27300 0925540bef6708fe52f4c11975ffbf83 254 Pfam PF05138 Phenylacetic acid catabolic protein 3 254 1.4E-96 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CVS48_RS27300 0925540bef6708fe52f4c11975ffbf83 254 SUPERFAMILY SSF47240 3 248 1.46E-81 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS12950 090a2529246d0de1cf0901370347683f 542 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 68 487 9.5E-91 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CVS48_RS12950 090a2529246d0de1cf0901370347683f 542 SUPERFAMILY SSF56317 234 517 4.97E-31 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS12950 090a2529246d0de1cf0901370347683f 542 Pfam PF00795 Carbon-nitrogen hydrolase 244 511 1.9E-23 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS12950 090a2529246d0de1cf0901370347683f 542 Gene3D G3DSA:3.60.110.10 227 506 6.2E-34 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS12950 090a2529246d0de1cf0901370347683f 542 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 8 525 21.156 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CVS48_RS15810 f2f918aefb7df32f9911257d872f2b0b 331 PIRSF PIRSF017082 1 330 3.2E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS15810 f2f918aefb7df32f9911257d872f2b0b 331 Gene3D G3DSA:3.40.190.10 130 241 1.8E-10 T 29-03-2018 CVS48_RS15810 f2f918aefb7df32f9911257d872f2b0b 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 327 8.2E-87 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS15810 f2f918aefb7df32f9911257d872f2b0b 331 SUPERFAMILY SSF53850 95 291 4.34E-15 T 29-03-2018 CVS48_RS26645 7d51a236085380efa77c6b4adbdc5127 368 Gene3D G3DSA:3.30.465.10 55 176 9.6E-28 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS26645 7d51a236085380efa77c6b4adbdc5127 368 Pfam PF01565 FAD binding domain 9 139 9.1E-21 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS26645 7d51a236085380efa77c6b4adbdc5127 368 SUPERFAMILY SSF56176 7 177 1.55E-32 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS26645 7d51a236085380efa77c6b4adbdc5127 368 Gene3D G3DSA:1.10.45.10 296 364 7.9E-4 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CVS48_RS26645 7d51a236085380efa77c6b4adbdc5127 368 SUPERFAMILY SSF55103 192 366 4.74E-12 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 SUPERFAMILY SSF52943 3 301 4.41E-88 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 287 300 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 301 3.1E-95 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 Gene3D G3DSA:1.10.287.80 5 158 1.0E-42 T 29-03-2018 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 301 34.169 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 Pfam PF00231 ATP synthase 4 300 6.7E-89 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 Gene3D G3DSA:1.10.287.80 159 254 1.7E-21 T 29-03-2018 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 Gene3D G3DSA:1.10.287.80 255 296 9.9E-13 T 29-03-2018 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 PRINTS PR00126 ATP synthase gamma subunit signature 279 300 1.0E-33 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 PRINTS PR00126 ATP synthase gamma subunit signature 248 267 1.0E-33 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.0E-33 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04095 7ed75ee663cafb485e0a6a0670734b44 301 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.0E-33 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 423 494 3.6E-11 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 SUPERFAMILY SSF141868 4 233 2.09E-53 T 29-03-2018 IPR001633 EAL domain CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 SMART SM00267 389 577 3.6E-6 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 Pfam PF00990 Diguanylate cyclase, GGDEF domain 405 504 2.5E-12 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 Gene3D G3DSA:3.30.70.270 401 571 3.0E-20 T 29-03-2018 CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 SUPERFAMILY SSF54631 275 405 4.85E-10 T 29-03-2018 CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 SMART SM00052 1 238 2.5E-25 T 29-03-2018 IPR001633 EAL domain CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 Pfam PF00563 EAL domain 6 233 5.4E-48 T 29-03-2018 IPR001633 EAL domain CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 Pfam PF00571 CBS domain 284 317 2.3E-4 T 29-03-2018 IPR000644 CBS domain CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 SUPERFAMILY SSF55073 406 504 2.9E-17 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 Gene3D G3DSA:3.10.580.10 263 400 9.2E-10 T 29-03-2018 CVS48_RS19495 d325ecf277a15b899a5bb00b5c471aac 589 Gene3D G3DSA:3.20.20.450 5 236 2.5E-54 T 29-03-2018 IPR001633 EAL domain CVS48_RS28255 a7b3933a4bb3d6af6100cbe313241eec 195 Gene3D G3DSA:2.40.50.140 6 85 3.5E-19 T 29-03-2018 CVS48_RS28255 a7b3933a4bb3d6af6100cbe313241eec 195 SUPERFAMILY SSF50249 10 82 1.71E-11 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS28255 a7b3933a4bb3d6af6100cbe313241eec 195 Pfam PF11967 Recombination protein O N terminal 11 82 3.3E-18 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CVS48_RS28255 a7b3933a4bb3d6af6100cbe313241eec 195 SUPERFAMILY SSF57863 91 148 1.62E-7 T 29-03-2018 CVS48_RS28255 a7b3933a4bb3d6af6100cbe313241eec 195 Hamap MF_00201 DNA repair protein RecO [recO]. 7 192 14.071 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CVS48_RS28255 a7b3933a4bb3d6af6100cbe313241eec 195 TIGRFAM TIGR00613 reco: DNA repair protein RecO 13 153 5.5E-20 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CVS48_RS28255 a7b3933a4bb3d6af6100cbe313241eec 195 Pfam PF02565 Recombination protein O C terminal 87 152 5.9E-16 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 19.94 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 29-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 Pfam PF01165 Ribosomal protein S21 4 57 7.6E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 4.0E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 4.0E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 4.0E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 4.0E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 Gene3D G3DSA:1.20.5.1150 16 52 6.2E-17 T 29-03-2018 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.0E-23 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14760 6d383598a056f513052a39578b6d37ff 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 57 1.0E-16 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 Gene3D G3DSA:3.40.190.10 179 267 1.2E-28 T 29-03-2018 CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 Gene3D G3DSA:1.10.10.10 2 86 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 Gene3D G3DSA:3.40.190.10 91 178 3.0E-11 T 29-03-2018 CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 Pfam PF03466 LysR substrate binding domain 90 294 7.8E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 SUPERFAMILY SSF46785 5 90 2.52E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17470 fccfb10402fc99b6a16ee3740533a97b 306 SUPERFAMILY SSF53850 90 296 9.1E-41 T 29-03-2018 CVS48_RS15140 a7d22333cd8859e3fdc18cf413701fa0 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CVS48_RS15140 a7d22333cd8859e3fdc18cf413701fa0 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CVS48_RS15140 a7d22333cd8859e3fdc18cf413701fa0 89 Pfam PF00381 PTS HPr component phosphorylation site 3 82 2.6E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CVS48_RS15140 a7d22333cd8859e3fdc18cf413701fa0 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.2E-15 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CVS48_RS15140 a7d22333cd8859e3fdc18cf413701fa0 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 3.2E-15 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CVS48_RS15140 a7d22333cd8859e3fdc18cf413701fa0 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 3.2E-15 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CVS48_RS15140 a7d22333cd8859e3fdc18cf413701fa0 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 5.0E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CVS48_RS15140 a7d22333cd8859e3fdc18cf413701fa0 89 SUPERFAMILY SSF55594 1 87 6.93E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CVS48_RS15140 a7d22333cd8859e3fdc18cf413701fa0 89 Gene3D G3DSA:3.30.1340.10 1 87 2.2E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 SMART SM00245 173 378 1.8E-59 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 Gene3D G3DSA:3.90.226.10 182 457 2.9E-64 T 29-03-2018 CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 SMART SM00228 100 171 2.3E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 Pfam PF03572 Peptidase family S41 199 377 2.8E-52 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 Pfam PF13180 PDZ domain 100 176 3.1E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 SUPERFAMILY SSF50156 89 183 4.15E-20 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 Gene3D G3DSA:2.30.42.10 100 181 6.0E-17 T 29-03-2018 CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 52 380 4.5E-94 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 SUPERFAMILY SSF52096 192 386 9.61E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 SUPERFAMILY SSF52096 39 118 9.61E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS08025 a071118f2b8ef9d0ff23146e23aba0d5 481 Gene3D G3DSA:3.30.750.44 40 99 1.8E-15 T 29-03-2018 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 2.4E-55 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.001 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 PIRSF PIRSF002158 6 275 2.0E-100 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 Gene3D G3DSA:2.30.30.30 119 195 1.4E-30 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 Gene3D G3DSA:4.10.950.10 197 273 2.9E-35 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.1E-32 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 SUPERFAMILY SSF50249 3 124 1.58E-46 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 Gene3D G3DSA:2.40.50.140 1 114 2.1E-43 T 29-03-2018 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 SMART SM01383 42 118 2.6E-42 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 SMART SM01382 124 252 2.2E-87 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 SUPERFAMILY SSF50104 127 272 7.82E-60 T 29-03-2018 IPR008991 Translation protein SH3-like domain CVS48_RS06400 06672f855accc09c2bce0d9e5c8d353b 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 2.8E-127 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CVS48_RS27895 cf6b3171eec804ee7b3e2ceae2baafab 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS27895 cf6b3171eec804ee7b3e2ceae2baafab 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 113 1.6E-33 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27895 cf6b3171eec804ee7b3e2ceae2baafab 238 Gene3D G3DSA:3.10.20.30 1 107 6.0E-34 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS27895 cf6b3171eec804ee7b3e2ceae2baafab 238 SUPERFAMILY SSF46548 108 236 6.98E-39 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CVS48_RS27895 cf6b3171eec804ee7b3e2ceae2baafab 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 230 3.7E-85 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27895 cf6b3171eec804ee7b3e2ceae2baafab 238 Gene3D G3DSA:1.10.1060.10 108 238 6.9E-31 T 29-03-2018 CVS48_RS27895 cf6b3171eec804ee7b3e2ceae2baafab 238 SUPERFAMILY SSF54292 5 107 8.19E-30 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS27895 cf6b3171eec804ee7b3e2ceae2baafab 238 Pfam PF13534 4Fe-4S dicluster domain 148 221 4.2E-10 T 29-03-2018 CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 Gene3D G3DSA:3.40.50.300 328 592 3.3E-51 T 29-03-2018 CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 SUPERFAMILY SSF52540 335 576 1.81E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 Gene3D G3DSA:3.40.50.300 596 828 2.5E-54 T 29-03-2018 CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 Pfam PF00005 ABC transporter 615 758 2.8E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 Pfam PF00005 ABC transporter 352 505 2.9E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 ProSitePatterns PS00211 ABC transporters family signature. 731 745 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 SUPERFAMILY SSF52540 599 824 1.22E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 556 576 3.6E-6 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 Gene3D G3DSA:1.10.3470.10 2 299 7.3E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 295 2.6E-41 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 SMART SM00382 624 807 1.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS07335 dee3ba6b5d0393828e0fde2bdc56511a 830 SMART SM00382 360 554 4.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS25155 213a94e2788986487cf4b0d099d982e9 147 Gene3D G3DSA:3.40.50.9100 1 145 7.0E-52 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25155 213a94e2788986487cf4b0d099d982e9 147 PIRSF PIRSF001399 1 145 3.3E-48 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25155 213a94e2788986487cf4b0d099d982e9 147 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 147 54.767 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25155 213a94e2788986487cf4b0d099d982e9 147 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 3 144 2.0E-37 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25155 213a94e2788986487cf4b0d099d982e9 147 SUPERFAMILY SSF52304 1 144 1.57E-49 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS25155 213a94e2788986487cf4b0d099d982e9 147 Pfam PF01220 Dehydroquinase class II 2 138 4.2E-47 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 3.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 Pfam PF00106 short chain dehydrogenase 9 197 3.8E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 Gene3D G3DSA:3.40.50.720 2 238 9.6E-57 T 29-03-2018 CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 186 1.1E-4 T 29-03-2018 CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 5.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 SUPERFAMILY SSF51735 1 221 1.11E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS08635 f2ee5f4a26bf0dcffdd347ff962aeb17 291 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS25355 01eace9ad5044e346bc69ce3eed130f0 525 Gene3D G3DSA:3.40.190.10 186 286 1.8E-20 T 29-03-2018 CVS48_RS25355 01eace9ad5044e346bc69ce3eed130f0 525 PIRSF PIRSF002741 1 515 1.4E-85 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS25355 01eace9ad5044e346bc69ce3eed130f0 525 Gene3D G3DSA:3.10.105.10 287 494 6.3E-46 T 29-03-2018 CVS48_RS25355 01eace9ad5044e346bc69ce3eed130f0 525 SUPERFAMILY SSF53850 26 509 2.37E-112 T 29-03-2018 CVS48_RS25355 01eace9ad5044e346bc69ce3eed130f0 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 436 1.4E-84 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS25355 01eace9ad5044e346bc69ce3eed130f0 525 Gene3D G3DSA:3.90.76.10 39 185 2.2E-33 T 29-03-2018 CVS48_RS09550 124df0016b82349e68d9b41374c377c7 126 Gene3D G3DSA:2.60.120.10 33 124 6.2E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS09550 124df0016b82349e68d9b41374c377c7 126 SUPERFAMILY SSF51182 38 116 1.45E-11 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS09550 124df0016b82349e68d9b41374c377c7 126 Pfam PF07883 Cupin domain 55 115 4.0E-8 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 Pfam PF00490 Delta-aminolevulinic acid dehydratase 13 332 1.7E-137 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 Gene3D G3DSA:3.20.20.70 2 338 1.8E-149 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 SUPERFAMILY SSF51569 7 335 5.13E-143 T 29-03-2018 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 308 327 2.8E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 161 180 2.8E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 278 293 2.8E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 253 269 2.8E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 199 218 2.8E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 130 144 2.8E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 253 265 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 PIRSF PIRSF001415 4 337 5.6E-146 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS06600 1ce18de77252ea32d21c9384c139eb9b 338 SMART SM01004 10 334 4.1E-237 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CVS48_RS28230 5aeba18ddd3fdfdbe5c74a8d37d5a32a 430 Pfam PF07690 Major Facilitator Superfamily 33 336 7.4E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS28230 5aeba18ddd3fdfdbe5c74a8d37d5a32a 430 SUPERFAMILY SSF103473 30 422 1.7E-30 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS28230 5aeba18ddd3fdfdbe5c74a8d37d5a32a 430 Gene3D G3DSA:1.20.1250.20 24 219 4.3E-14 T 29-03-2018 CVS48_RS28230 5aeba18ddd3fdfdbe5c74a8d37d5a32a 430 Gene3D G3DSA:1.20.1250.20 228 428 1.1E-4 T 29-03-2018 CVS48_RS02335 3efbbde2405af8c09975364c59e721d4 741 SUPERFAMILY SSF51445 236 577 1.08E-38 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS02335 3efbbde2405af8c09975364c59e721d4 741 Gene3D G3DSA:2.60.40.1180 599 659 5.5E-24 T 29-03-2018 CVS48_RS02335 3efbbde2405af8c09975364c59e721d4 741 Gene3D G3DSA:2.60.40.1760 16 233 8.8E-30 T 29-03-2018 CVS48_RS02335 3efbbde2405af8c09975364c59e721d4 741 SUPERFAMILY SSF74650 14 233 1.41E-27 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CVS48_RS02335 3efbbde2405af8c09975364c59e721d4 741 Gene3D G3DSA:3.20.20.80 234 598 1.9E-68 T 29-03-2018 CVS48_RS02335 3efbbde2405af8c09975364c59e721d4 741 Pfam PF01055 Glycosyl hydrolases family 31 228 663 1.9E-76 T 29-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CVS48_RS02335 3efbbde2405af8c09975364c59e721d4 741 SUPERFAMILY SSF51011 579 658 4.24E-21 T 29-03-2018 CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 SUPERFAMILY SSF54909 66 153 1.61E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 Gene3D G3DSA:3.30.70.920 57 150 3.5E-23 T 29-03-2018 CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 Gene3D G3DSA:1.10.10.10 4 55 4.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 Pfam PF01037 Lrp/AsnC ligand binding domain 71 144 1.9E-18 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 6.2E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 6.2E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 6.2E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 SMART SM00344 4 113 7.1E-48 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 1.0E-19 T 29-03-2018 CVS48_RS19965 09a178cbf347da7ac5aa7e596a87d641 155 SUPERFAMILY SSF46785 4 63 7.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12460 ec6ac76b352ab596c7f9bc660d876da2 183 Gene3D G3DSA:3.40.50.2300 7 123 7.2E-25 T 29-03-2018 CVS48_RS12460 ec6ac76b352ab596c7f9bc660d876da2 183 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 139 156 2.5E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS12460 ec6ac76b352ab596c7f9bc660d876da2 183 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 156 176 2.5E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS12460 ec6ac76b352ab596c7f9bc660d876da2 183 SUPERFAMILY SSF52172 8 145 3.08E-28 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS12460 ec6ac76b352ab596c7f9bc660d876da2 183 Pfam PF00072 Response regulator receiver domain 8 111 1.2E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12460 ec6ac76b352ab596c7f9bc660d876da2 183 Gene3D G3DSA:1.10.10.60 126 171 1.5E-15 T 29-03-2018 CVS48_RS12460 ec6ac76b352ab596c7f9bc660d876da2 183 SUPERFAMILY SSF46689 132 172 1.67E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS12460 ec6ac76b352ab596c7f9bc660d876da2 183 Pfam PF02954 Bacterial regulatory protein, Fis family 136 172 6.5E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS12460 ec6ac76b352ab596c7f9bc660d876da2 183 SMART SM00448 7 116 2.0E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 PIRSF PIRSF002583 1 632 7.1E-217 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 Gene3D G3DSA:3.30.565.10 2 231 1.2E-54 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 31 40 - T 29-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 Pfam PF00183 Hsp90 protein 220 630 4.4E-130 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 SUPERFAMILY SSF55874 10 220 5.37E-67 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 SUPERFAMILY SSF54211 238 493 3.11E-100 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 SUPERFAMILY SSF110942 519 631 7.45E-34 T 29-03-2018 CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 Hamap MF_00505 Chaperone protein HtpG [htpG]. 8 631 32.604 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 SMART SM00387 33 188 4.8E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 186 5.7E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 PRINTS PR00775 90kDa heat shock protein signature 176 193 1.3E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 PRINTS PR00775 90kDa heat shock protein signature 99 116 1.3E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 PRINTS PR00775 90kDa heat shock protein signature 32 54 1.3E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 PRINTS PR00775 90kDa heat shock protein signature 81 98 1.3E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 PRINTS PR00775 90kDa heat shock protein signature 194 212 1.3E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 PRINTS PR00775 90kDa heat shock protein signature 11 31 1.3E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CVS48_RS09740 8a1200dfe5179ac9a78fa8e8b14065dc 632 PRINTS PR00775 90kDa heat shock protein signature 126 148 1.3E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CVS48_RS07490 af33e6fd5b80ada6f38959578c6e8a14 387 Pfam PF13439 Glycosyltransferase Family 4 28 174 5.5E-15 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS07490 af33e6fd5b80ada6f38959578c6e8a14 387 Pfam PF00534 Glycosyl transferases group 1 186 350 2.4E-36 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS07490 af33e6fd5b80ada6f38959578c6e8a14 387 Gene3D G3DSA:3.40.50.2000 12 182 3.3E-18 T 29-03-2018 CVS48_RS07490 af33e6fd5b80ada6f38959578c6e8a14 387 Gene3D G3DSA:3.40.50.2000 183 357 1.3E-52 T 29-03-2018 CVS48_RS07490 af33e6fd5b80ada6f38959578c6e8a14 387 SUPERFAMILY SSF53756 18 370 1.62E-78 T 29-03-2018 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 SUPERFAMILY SSF48600 3 92 2.01E-19 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 SUPERFAMILY SSF53850 94 278 1.41E-58 T 29-03-2018 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 Pfam PF00800 Prephenate dehydratase 96 270 2.3E-61 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 308 315 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 Gene3D G3DSA:3.30.70.260 271 361 6.2E-27 T 29-03-2018 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 PIRSF PIRSF001500 2 361 1.8E-141 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 Gene3D G3DSA:1.20.59.10 3 102 5.9E-33 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 Pfam PF01842 ACT domain 282 343 1.7E-7 T 29-03-2018 IPR002912 ACT domain CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 Gene3D G3DSA:3.40.190.10 103 184 1.5E-33 T 29-03-2018 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 Gene3D G3DSA:3.40.190.10 185 259 2.5E-27 T 29-03-2018 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 SMART SM00830 13 94 2.9E-28 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 SUPERFAMILY SSF55021 265 359 3.7E-25 T 29-03-2018 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 TIGRFAM TIGR01807 CM_P2: chorismate mutase 9 84 3.3E-25 T 29-03-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 CVS48_RS27520 52ed10175135943592e97ff4b373eb0b 361 Pfam PF01817 Chorismate mutase type II 13 91 8.9E-22 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS26185 39ca8d6b8e93923d025abc557647e7d4 452 Gene3D G3DSA:3.40.1160.10 20 305 3.5E-57 T 29-03-2018 CVS48_RS26185 39ca8d6b8e93923d025abc557647e7d4 452 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 22 452 8.5E-179 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS26185 39ca8d6b8e93923d025abc557647e7d4 452 SUPERFAMILY SSF55729 308 430 2.19E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS26185 39ca8d6b8e93923d025abc557647e7d4 452 Pfam PF00696 Amino acid kinase family 39 275 1.7E-29 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS26185 39ca8d6b8e93923d025abc557647e7d4 452 Pfam PF00583 Acetyltransferase (GNAT) family 345 413 2.4E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS26185 39ca8d6b8e93923d025abc557647e7d4 452 Gene3D G3DSA:3.40.630.30 307 452 1.7E-23 T 29-03-2018 CVS48_RS26185 39ca8d6b8e93923d025abc557647e7d4 452 SUPERFAMILY SSF53633 20 303 1.54E-59 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS26185 39ca8d6b8e93923d025abc557647e7d4 452 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 452 193.283 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS26185 39ca8d6b8e93923d025abc557647e7d4 452 PIRSF PIRSF000423 12 452 5.2E-184 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS06960 06fe8825f158b3802ca8776912513068 289 Pfam PF00892 EamA-like transporter family 150 281 4.1E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS06960 06fe8825f158b3802ca8776912513068 289 Pfam PF00892 EamA-like transporter family 9 136 9.1E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS06960 06fe8825f158b3802ca8776912513068 289 SUPERFAMILY SSF103481 185 281 4.58E-13 T 29-03-2018 CVS48_RS06960 06fe8825f158b3802ca8776912513068 289 SUPERFAMILY SSF103481 38 139 1.44E-17 T 29-03-2018 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Gene3D G3DSA:2.70.20.10 364 474 2.0E-22 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 312 327 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 SMART SM00493 2 122 3.6E-4 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 SUPERFAMILY SSF57783 733 766 5.44E-9 T 29-03-2018 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Pfam PF01751 Toprim domain 3 129 3.0E-9 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Gene3D G3DSA:3.40.50.140 2 150 3.5E-26 T 29-03-2018 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Gene3D G3DSA:3.30.65.10 715 777 3.0E-13 T 29-03-2018 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Gene3D G3DSA:3.30.65.10 786 846 3.5E-7 T 29-03-2018 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Gene3D G3DSA:1.10.460.10 475 672 2.2E-20 T 29-03-2018 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Gene3D G3DSA:1.10.460.10 151 363 6.3E-34 T 29-03-2018 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 188 206 2.2E-24 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 399 415 2.2E-24 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 318 327 2.2E-24 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 96 109 2.2E-24 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 516 530 2.2E-24 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Pfam PF01131 DNA topoisomerase 149 602 5.3E-107 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 SMART SM00436 122 218 6.1E-22 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 SUPERFAMILY SSF56712 2 616 1.05E-153 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Pfam PF13342 C-terminal repeat of topoisomerase 654 713 1.5E-16 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 735 768 4.5E-11 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 806 842 6.8E-9 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CVS48_RS08165 6919b445e561094639a1de3ce4d960a3 847 SMART SM00437 275 564 3.7E-65 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CVS48_RS07785 5abb0f4c776f0611cdcbc0a1830e915f 181 Gene3D G3DSA:1.10.10.10 3 172 6.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07785 5abb0f4c776f0611cdcbc0a1830e915f 181 PIRSF PIRSF006707 1 174 8.3E-54 T 29-03-2018 IPR026282 DNA-binding protein, MJ1563 type CVS48_RS07785 5abb0f4c776f0611cdcbc0a1830e915f 181 Pfam PF12802 MarR family 26 80 2.4E-7 T 29-03-2018 CVS48_RS07785 5abb0f4c776f0611cdcbc0a1830e915f 181 SUPERFAMILY SSF46785 4 148 9.24E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03350 04ba9fe0d4fb116cca2606e3ba6de500 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS03350 04ba9fe0d4fb116cca2606e3ba6de500 425 SUPERFAMILY SSF53383 2 423 3.42E-132 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS03350 04ba9fe0d4fb116cca2606e3ba6de500 425 Gene3D G3DSA:3.90.1150.10 312 425 4.1E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS03350 04ba9fe0d4fb116cca2606e3ba6de500 425 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 423 1.1E-186 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CVS48_RS03350 04ba9fe0d4fb116cca2606e3ba6de500 425 Pfam PF00202 Aminotransferase class-III 32 394 1.2E-76 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS03350 04ba9fe0d4fb116cca2606e3ba6de500 425 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 425 103.911 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CVS48_RS03350 04ba9fe0d4fb116cca2606e3ba6de500 425 Gene3D G3DSA:3.90.1150.10 1 184 1.2E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS03350 04ba9fe0d4fb116cca2606e3ba6de500 425 Gene3D G3DSA:3.40.640.10 185 311 6.4E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 SUPERFAMILY SSF52440 7 99 3.45E-31 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 Gene3D G3DSA:3.40.50.20 1 100 1.0E-35 T 29-03-2018 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 66 77 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 PIRSF PIRSF039102 44 314 1.9E-88 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 PIRSF PIRSF039102 4 50 3.6E-8 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 SUPERFAMILY SSF56059 99 302 1.13E-57 T 29-03-2018 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 Gene3D G3DSA:3.30.1490.20 101 168 1.2E-16 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 Pfam PF07478 D-ala D-ala ligase C-terminus 107 302 7.7E-56 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 305 9.5E-99 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 306 36.26 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 Pfam PF01820 D-ala D-ala ligase N-terminus 7 89 6.3E-20 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 248 276 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 Gene3D G3DSA:3.30.470.20 169 315 1.9E-43 T 29-03-2018 CVS48_RS02460 e820d2eb3b4a3be79bba193ba6cd6575 316 SMART SM01209 98 273 0.0065 T 29-03-2018 CVS48_RS01195 648b60b01eb7b421bda857de514a8696 540 Gene3D G3DSA:3.40.50.980 19 193 3.5E-35 T 29-03-2018 CVS48_RS01195 648b60b01eb7b421bda857de514a8696 540 Gene3D G3DSA:3.30.300.30 438 539 2.8E-27 T 29-03-2018 CVS48_RS01195 648b60b01eb7b421bda857de514a8696 540 Gene3D G3DSA:3.40.50.980 194 348 7.8E-35 T 29-03-2018 CVS48_RS01195 648b60b01eb7b421bda857de514a8696 540 SUPERFAMILY SSF56801 14 538 3.53E-139 T 29-03-2018 CVS48_RS01195 648b60b01eb7b421bda857de514a8696 540 Pfam PF00501 AMP-binding enzyme 24 443 4.1E-92 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS01195 648b60b01eb7b421bda857de514a8696 540 Gene3D G3DSA:2.30.38.10 362 437 2.7E-20 T 29-03-2018 CVS48_RS01195 648b60b01eb7b421bda857de514a8696 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS01195 648b60b01eb7b421bda857de514a8696 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 526 2.1E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS07055 fc05396be70ed1c17f3511cee5944437 251 Gene3D G3DSA:3.90.550.10 1 223 9.3E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS07055 fc05396be70ed1c17f3511cee5944437 251 Pfam PF02348 Cytidylyltransferase 9 153 2.1E-18 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CVS48_RS07055 fc05396be70ed1c17f3511cee5944437 251 SUPERFAMILY SSF53448 5 199 3.67E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 SUPERFAMILY SSF69065 2 152 1.74E-48 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 SMART SM00535 18 146 3.3E-53 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 Gene3D G3DSA:3.30.160.20 152 243 4.9E-16 T 29-03-2018 CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 217 29.286 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 Gene3D G3DSA:1.10.1520.10 1 148 1.1E-44 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 Pfam PF00035 Double-stranded RNA binding motif 153 218 2.8E-9 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 Pfam PF14622 Ribonuclease-III-like 16 139 9.5E-39 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 SMART SM00358 153 221 3.6E-13 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 SUPERFAMILY SSF54768 106 220 2.2E-22 T 29-03-2018 CVS48_RS28265 d3c035209cf633157b9461e00513633c 253 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 6 219 4.9E-69 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CVS48_RS21815 9659288bec9274c39e37abb265d2b94b 251 Pfam PF00106 short chain dehydrogenase 5 199 7.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21815 9659288bec9274c39e37abb265d2b94b 251 SUPERFAMILY SSF51735 3 238 9.85E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS21815 9659288bec9274c39e37abb265d2b94b 251 Gene3D G3DSA:3.40.50.720 1 244 5.8E-43 T 29-03-2018 CVS48_RS21815 9659288bec9274c39e37abb265d2b94b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21815 9659288bec9274c39e37abb265d2b94b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21815 9659288bec9274c39e37abb265d2b94b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21815 9659288bec9274c39e37abb265d2b94b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21815 9659288bec9274c39e37abb265d2b94b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21815 9659288bec9274c39e37abb265d2b94b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 5.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.6E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 Gene3D G3DSA:2.40.30.10 302 395 4.6E-32 T 29-03-2018 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 SUPERFAMILY SSF50447 207 303 3.14E-30 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 Gene3D G3DSA:3.40.50.300 2 74 4.6E-10 T 29-03-2018 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 5.0E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 SUPERFAMILY SSF50465 304 396 2.35E-35 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 SUPERFAMILY SSF52540 5 221 5.31E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 5.1E-58 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 Gene3D G3DSA:3.40.50.300 75 205 2.5E-30 T 29-03-2018 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.02 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 2.9E-225 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.2E-32 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CVS48_RS06235 97f1f026eb2d4f4aed156a14aad3842c 396 Gene3D G3DSA:2.40.30.10 208 301 3.9E-30 T 29-03-2018 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.6E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 Gene3D G3DSA:2.40.30.10 302 395 4.6E-32 T 29-03-2018 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 SUPERFAMILY SSF50447 207 303 3.14E-30 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 Gene3D G3DSA:3.40.50.300 2 74 4.6E-10 T 29-03-2018 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 5.0E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 SUPERFAMILY SSF50465 304 396 2.35E-35 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 SUPERFAMILY SSF52540 5 221 5.31E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 8.3E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 5.1E-58 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 Gene3D G3DSA:3.40.50.300 75 205 2.5E-30 T 29-03-2018 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.02 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 2.9E-225 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.2E-32 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CVS48_RS06335 97f1f026eb2d4f4aed156a14aad3842c 396 Gene3D G3DSA:2.40.30.10 208 301 3.9E-30 T 29-03-2018 CVS48_RS03890 479f344721b66c38cf626807617f9ce6 304 Pfam PF03466 LysR substrate binding domain 92 298 6.4E-28 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS03890 479f344721b66c38cf626807617f9ce6 304 Gene3D G3DSA:3.40.190.10 181 273 9.6E-10 T 29-03-2018 CVS48_RS03890 479f344721b66c38cf626807617f9ce6 304 Gene3D G3DSA:3.40.190.10 89 180 8.0E-12 T 29-03-2018 CVS48_RS03890 479f344721b66c38cf626807617f9ce6 304 Gene3D G3DSA:1.10.10.10 1 84 8.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03890 479f344721b66c38cf626807617f9ce6 304 SUPERFAMILY SSF46785 3 85 6.81E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03890 479f344721b66c38cf626807617f9ce6 304 SUPERFAMILY SSF53850 93 296 5.25E-23 T 29-03-2018 CVS48_RS03890 479f344721b66c38cf626807617f9ce6 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.5E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12010 0471c4e7c3c211b9d55d434832e54c64 443 Pfam PF01593 Flavin containing amine oxidoreductase 36 308 1.2E-18 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CVS48_RS12010 0471c4e7c3c211b9d55d434832e54c64 443 PRINTS PR00757 Flavin-containing amine oxidase signature 218 240 1.9E-5 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CVS48_RS12010 0471c4e7c3c211b9d55d434832e54c64 443 PRINTS PR00757 Flavin-containing amine oxidase signature 28 47 1.9E-5 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CVS48_RS12010 0471c4e7c3c211b9d55d434832e54c64 443 Gene3D G3DSA:3.90.660.20 58 431 3.0E-34 T 29-03-2018 CVS48_RS12010 0471c4e7c3c211b9d55d434832e54c64 443 SUPERFAMILY SSF51905 402 431 7.77E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS12010 0471c4e7c3c211b9d55d434832e54c64 443 SUPERFAMILY SSF51905 28 322 7.77E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23950 bdc3223a5354d45f0aeebf2ab0f2860f 515 Gene3D G3DSA:3.30.300.30 400 513 8.0E-25 T 29-03-2018 CVS48_RS23950 bdc3223a5354d45f0aeebf2ab0f2860f 515 SUPERFAMILY SSF56801 7 503 1.01E-129 T 29-03-2018 CVS48_RS23950 bdc3223a5354d45f0aeebf2ab0f2860f 515 Gene3D G3DSA:3.40.50.980 170 318 1.1E-46 T 29-03-2018 CVS48_RS23950 bdc3223a5354d45f0aeebf2ab0f2860f 515 Pfam PF00501 AMP-binding enzyme 22 405 2.9E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS23950 bdc3223a5354d45f0aeebf2ab0f2860f 515 Gene3D G3DSA:2.30.38.10 319 398 5.4E-17 T 29-03-2018 CVS48_RS23950 bdc3223a5354d45f0aeebf2ab0f2860f 515 Gene3D G3DSA:3.40.50.980 4 169 1.8E-37 T 29-03-2018 CVS48_RS23950 bdc3223a5354d45f0aeebf2ab0f2860f 515 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS23950 bdc3223a5354d45f0aeebf2ab0f2860f 515 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 492 8.3E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS27470 59cecc3989762464ba9057e83ad0a476 329 Gene3D G3DSA:3.40.50.720 1 163 6.4E-18 T 29-03-2018 CVS48_RS27470 59cecc3989762464ba9057e83ad0a476 329 Gene3D G3DSA:3.90.25.10 164 329 1.2E-24 T 29-03-2018 CVS48_RS27470 59cecc3989762464ba9057e83ad0a476 329 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 328 49.26 T 29-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 CVS48_RS27470 59cecc3989762464ba9057e83ad0a476 329 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 325 1.0E-127 T 29-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 CVS48_RS27470 59cecc3989762464ba9057e83ad0a476 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 240 2.8E-43 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS27470 59cecc3989762464ba9057e83ad0a476 329 SUPERFAMILY SSF51735 2 327 5.79E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS08620 2d114e23635ae1384490fa1eb6ef404c 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS08620 2d114e23635ae1384490fa1eb6ef404c 545 SUPERFAMILY SSF56801 16 524 2.22E-123 T 29-03-2018 CVS48_RS08620 2d114e23635ae1384490fa1eb6ef404c 545 Pfam PF00501 AMP-binding enzyme 21 430 6.2E-76 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS08620 2d114e23635ae1384490fa1eb6ef404c 545 Gene3D G3DSA:3.40.50.980 15 194 3.1E-36 T 29-03-2018 CVS48_RS08620 2d114e23635ae1384490fa1eb6ef404c 545 Gene3D G3DSA:3.30.300.30 426 543 2.9E-26 T 29-03-2018 CVS48_RS08620 2d114e23635ae1384490fa1eb6ef404c 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 439 514 2.1E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS08620 2d114e23635ae1384490fa1eb6ef404c 545 Gene3D G3DSA:3.40.50.980 195 339 8.8E-23 T 29-03-2018 CVS48_RS08620 2d114e23635ae1384490fa1eb6ef404c 545 Gene3D G3DSA:2.30.38.10 340 423 3.5E-20 T 29-03-2018 CVS48_RS02165 8589a182b33f61f1a1acc4f9d5b11083 986 SUPERFAMILY SSF69279 284 331 8.16E-5 T 29-03-2018 CVS48_RS02165 8589a182b33f61f1a1acc4f9d5b11083 986 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 634 737 4.0E-30 T 29-03-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain CVS48_RS02165 8589a182b33f61f1a1acc4f9d5b11083 986 SUPERFAMILY SSF69279 18 201 5.55E-41 T 29-03-2018 CVS48_RS02165 8589a182b33f61f1a1acc4f9d5b11083 986 Gene3D G3DSA:3.55.50.10 105 203 4.2E-23 T 29-03-2018 CVS48_RS02165 8589a182b33f61f1a1acc4f9d5b11083 986 Pfam PF05954 Phage late control gene D protein (GPD) 36 357 2.0E-65 T 29-03-2018 CVS48_RS02165 8589a182b33f61f1a1acc4f9d5b11083 986 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 802 956 3.8E-35 T 29-03-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal CVS48_RS02165 8589a182b33f61f1a1acc4f9d5b11083 986 SUPERFAMILY SSF69255 471 564 1.91E-20 T 29-03-2018 CVS48_RS02165 8589a182b33f61f1a1acc4f9d5b11083 986 Gene3D G3DSA:2.40.50.260 470 592 4.9E-25 T 29-03-2018 CVS48_RS15225 31da7023fa1971015930630dda34c305 304 PIRSF PIRSF016184 1 300 3.0E-74 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CVS48_RS15225 31da7023fa1971015930630dda34c305 304 Gene3D G3DSA:3.10.310.10 134 288 4.5E-30 T 29-03-2018 CVS48_RS15225 31da7023fa1971015930630dda34c305 304 Pfam PF02567 Phenazine biosynthesis-like protein 9 296 8.5E-54 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CVS48_RS15225 31da7023fa1971015930630dda34c305 304 SUPERFAMILY SSF54506 1 297 9.42E-61 T 29-03-2018 CVS48_RS15225 31da7023fa1971015930630dda34c305 304 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 298 7.8E-58 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CVS48_RS15225 31da7023fa1971015930630dda34c305 304 Gene3D G3DSA:3.10.310.10 1 133 4.5E-31 T 29-03-2018 CVS48_RS12805 13b1839d5458582cb6c1b1ad38c77f2c 555 Gene3D G3DSA:1.20.1250.20 28 251 1.2E-17 T 29-03-2018 CVS48_RS12805 13b1839d5458582cb6c1b1ad38c77f2c 555 SUPERFAMILY SSF103473 28 489 1.57E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS12805 13b1839d5458582cb6c1b1ad38c77f2c 555 Gene3D G3DSA:1.20.1250.20 263 500 9.6E-22 T 29-03-2018 CVS48_RS12805 13b1839d5458582cb6c1b1ad38c77f2c 555 Pfam PF07690 Major Facilitator Superfamily 40 441 1.5E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS26210 40ca20b3c6343e78f198ba60e41a0565 562 SUPERFAMILY SSF47203 299 457 6.77E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS26210 40ca20b3c6343e78f198ba60e41a0565 562 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 186 198 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS26210 40ca20b3c6343e78f198ba60e41a0565 562 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 413 432 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS26210 40ca20b3c6343e78f198ba60e41a0565 562 SUPERFAMILY SSF56645 69 299 1.69E-32 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS26210 40ca20b3c6343e78f198ba60e41a0565 562 Gene3D G3DSA:2.40.110.10 184 288 4.9E-19 T 29-03-2018 CVS48_RS26210 40ca20b3c6343e78f198ba60e41a0565 562 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 292 454 8.6E-32 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS26210 40ca20b3c6343e78f198ba60e41a0565 562 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 184 282 2.9E-14 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS26210 40ca20b3c6343e78f198ba60e41a0565 562 Gene3D G3DSA:1.20.140.10 289 463 8.7E-36 T 29-03-2018 CVS48_RS11590 7a94cf0e5f301f2bf4b1bd50541c29ca 305 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 302 7.5E-21 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CVS48_RS11590 7a94cf0e5f301f2bf4b1bd50541c29ca 305 SUPERFAMILY SSF52283 7 130 1.55E-23 T 29-03-2018 CVS48_RS11590 7a94cf0e5f301f2bf4b1bd50541c29ca 305 Gene3D G3DSA:3.40.50.720 1 110 1.0E-21 T 29-03-2018 CVS48_RS11590 7a94cf0e5f301f2bf4b1bd50541c29ca 305 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 186 208 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CVS48_RS11590 7a94cf0e5f301f2bf4b1bd50541c29ca 305 SUPERFAMILY SSF51735 95 277 1.36E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11590 7a94cf0e5f301f2bf4b1bd50541c29ca 305 Gene3D G3DSA:3.40.50.720 111 279 8.5E-53 T 29-03-2018 CVS48_RS11590 7a94cf0e5f301f2bf4b1bd50541c29ca 305 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 215 231 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CVS48_RS11590 7a94cf0e5f301f2bf4b1bd50541c29ca 305 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 276 8.3E-55 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS12960 7d65bc3f53bfdd939bfef7451c07deea 158 SUPERFAMILY SSF55486 34 155 1.95E-37 T 29-03-2018 CVS48_RS12960 7d65bc3f53bfdd939bfef7451c07deea 158 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 152 19.788 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CVS48_RS12960 7d65bc3f53bfdd939bfef7451c07deea 158 Gene3D G3DSA:3.40.390.30 1 158 8.3E-40 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CVS48_RS12960 7d65bc3f53bfdd939bfef7451c07deea 158 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 46 148 7.0E-28 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CVS48_RS12960 7d65bc3f53bfdd939bfef7451c07deea 158 Pfam PF02130 Uncharacterized protein family UPF0054 27 147 2.3E-28 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CVS48_RS00595 3b6be53a7a4a6657fb3a4cb225be9a77 326 Pfam PF13533 Biotin-lipoyl like 2 45 4.5E-14 T 29-03-2018 CVS48_RS00595 3b6be53a7a4a6657fb3a4cb225be9a77 326 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 1 309 3.5E-71 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS00595 3b6be53a7a4a6657fb3a4cb225be9a77 326 Gene3D G3DSA:1.20.1600.10 38 316 4.9E-21 T 29-03-2018 CVS48_RS00595 3b6be53a7a4a6657fb3a4cb225be9a77 326 Gene3D G3DSA:3.90.1170.30 2 37 1.7E-4 T 29-03-2018 CVS48_RS00595 3b6be53a7a4a6657fb3a4cb225be9a77 326 SUPERFAMILY SSF111369 1 232 2.48E-62 T 29-03-2018 CVS48_RS14585 1e1b1697afcb901e8686016d8ba5cab5 574 Gene3D G3DSA:3.40.50.300 235 555 3.0E-29 T 29-03-2018 CVS48_RS14585 1e1b1697afcb901e8686016d8ba5cab5 574 Gene3D G3DSA:3.30.450.90 104 233 9.4E-17 T 29-03-2018 CVS48_RS14585 1e1b1697afcb901e8686016d8ba5cab5 574 SUPERFAMILY SSF52540 120 418 8.01E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14585 1e1b1697afcb901e8686016d8ba5cab5 574 Pfam PF00437 Type II/IV secretion system protein 134 406 4.1E-18 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS28090 49a42073ebfedc32756e313c95137c09 287 SUPERFAMILY SSF51735 4 259 3.89E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS28090 49a42073ebfedc32756e313c95137c09 287 Gene3D G3DSA:3.40.50.720 1 277 2.7E-33 T 29-03-2018 CVS48_RS28090 49a42073ebfedc32756e313c95137c09 287 Pfam PF13460 NAD(P)H-binding 11 161 6.4E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS28610 c2818c7fa689d50acd67262b00e3c1cf 163 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 159 4.1E-63 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CVS48_RS28610 c2818c7fa689d50acd67262b00e3c1cf 163 Gene3D G3DSA:3.30.1330.50 1 162 7.4E-72 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CVS48_RS28610 c2818c7fa689d50acd67262b00e3c1cf 163 SUPERFAMILY SSF69765 4 160 3.66E-64 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CVS48_RS28610 c2818c7fa689d50acd67262b00e3c1cf 163 Pfam PF02542 YgbB family 5 158 2.5E-63 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CVS48_RS28610 c2818c7fa689d50acd67262b00e3c1cf 163 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CVS48_RS28610 c2818c7fa689d50acd67262b00e3c1cf 163 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 160 35.436 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CVS48_RS13550 7a34057e965c9aadc5bf4fd4b9c4961d 397 Gene3D G3DSA:2.40.110.10 135 233 3.3E-30 T 29-03-2018 CVS48_RS13550 7a34057e965c9aadc5bf4fd4b9c4961d 397 SUPERFAMILY SSF47203 246 395 2.42E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS13550 7a34057e965c9aadc5bf4fd4b9c4961d 397 Gene3D G3DSA:1.10.540.10 1 134 2.2E-37 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS13550 7a34057e965c9aadc5bf4fd4b9c4961d 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 132 8.0E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS13550 7a34057e965c9aadc5bf4fd4b9c4961d 397 Gene3D G3DSA:1.20.140.10 234 397 2.2E-37 T 29-03-2018 CVS48_RS13550 7a34057e965c9aadc5bf4fd4b9c4961d 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 231 5.9E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS13550 7a34057e965c9aadc5bf4fd4b9c4961d 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 389 4.3E-29 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS13550 7a34057e965c9aadc5bf4fd4b9c4961d 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS13550 7a34057e965c9aadc5bf4fd4b9c4961d 397 SUPERFAMILY SSF56645 7 243 1.44E-76 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS24955 ddb88644a22284e1cbc5562c6cc944ce 154 SUPERFAMILY SSF47226 44 124 6.28E-14 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS24955 ddb88644a22284e1cbc5562c6cc944ce 154 Gene3D G3DSA:1.20.120.160 33 147 8.7E-13 T 29-03-2018 CVS48_RS24955 ddb88644a22284e1cbc5562c6cc944ce 154 Pfam PF01627 Hpt domain 61 138 6.2E-8 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.6E-26 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 Gene3D G3DSA:3.20.190.10 2 134 1.2E-34 T 29-03-2018 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 222 2.1E-20 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 SMART SM00898 2 115 1.2E-45 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 Pfam PF06827 Zinc finger found in FPG and IleRS 246 274 9.2E-10 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 SUPERFAMILY SSF81624 2 142 3.92E-38 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 Gene3D G3DSA:1.10.8.50 135 275 3.4E-43 T 29-03-2018 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 1.6E-81 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 SUPERFAMILY SSF57716 221 273 1.03E-14 T 29-03-2018 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 SUPERFAMILY SSF46946 134 225 1.19E-25 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 SMART SM01232 133 225 1.4E-39 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CVS48_RS10825 f4a903e26362eb67aa328fe83ecfc7ec 275 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 39.117 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CVS48_RS14700 f2cca52c9c7b82d7b6932c76711c1654 428 Gene3D G3DSA:3.40.50.800 328 427 3.5E-19 T 29-03-2018 IPR004154 Anticodon-binding CVS48_RS14700 f2cca52c9c7b82d7b6932c76711c1654 428 Pfam PF03129 Anticodon binding domain 332 426 2.1E-10 T 29-03-2018 IPR004154 Anticodon-binding CVS48_RS14700 f2cca52c9c7b82d7b6932c76711c1654 428 SUPERFAMILY SSF52954 329 425 1.34E-19 T 29-03-2018 IPR004154 Anticodon-binding CVS48_RS14700 f2cca52c9c7b82d7b6932c76711c1654 428 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 10 407 5.7E-151 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CVS48_RS14700 f2cca52c9c7b82d7b6932c76711c1654 428 Gene3D G3DSA:3.30.930.10 4 327 9.7E-71 T 29-03-2018 CVS48_RS14700 f2cca52c9c7b82d7b6932c76711c1654 428 Pfam PF13393 Histidyl-tRNA synthetase 13 315 7.5E-47 T 29-03-2018 CVS48_RS14700 f2cca52c9c7b82d7b6932c76711c1654 428 PIRSF PIRSF001549 4 428 1.7E-112 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CVS48_RS14700 f2cca52c9c7b82d7b6932c76711c1654 428 SUPERFAMILY SSF55681 10 319 3.83E-99 T 29-03-2018 CVS48_RS14700 f2cca52c9c7b82d7b6932c76711c1654 428 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 6 426 31.914 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CVS48_RS24145 52fedf1ccccde1a0d4bf7d45ff6cd515 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 121 296 3.2E-49 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS24145 52fedf1ccccde1a0d4bf7d45ff6cd515 329 Gene3D G3DSA:3.40.50.720 124 299 2.4E-49 T 29-03-2018 CVS48_RS24145 52fedf1ccccde1a0d4bf7d45ff6cd515 329 Gene3D G3DSA:3.40.50.720 4 123 1.5E-12 T 29-03-2018 CVS48_RS24145 52fedf1ccccde1a0d4bf7d45ff6cd515 329 SUPERFAMILY SSF51735 114 296 1.05E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS24145 52fedf1ccccde1a0d4bf7d45ff6cd515 329 SUPERFAMILY SSF52283 65 142 3.37E-6 T 29-03-2018 CVS48_RS09105 250f190971c0bea424ce3923bc08302e 264 PIRSF PIRSF002854 2 264 4.4E-94 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS09105 250f190971c0bea424ce3923bc08302e 264 Gene3D G3DSA:3.40.190.10 24 121 2.6E-19 T 29-03-2018 CVS48_RS09105 250f190971c0bea424ce3923bc08302e 264 SUPERFAMILY SSF53850 27 264 5.16E-81 T 29-03-2018 CVS48_RS09105 250f190971c0bea424ce3923bc08302e 264 Gene3D G3DSA:3.40.190.10 122 264 2.1E-51 T 29-03-2018 CVS48_RS09105 250f190971c0bea424ce3923bc08302e 264 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 16 264 1.6E-77 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS09105 250f190971c0bea424ce3923bc08302e 264 Pfam PF03180 NLPA lipoprotein 28 264 3.3E-88 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 9.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 9.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 434 9.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 9.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 SMART SM00387 366 475 1.3E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 SUPERFAMILY SSF55874 321 473 7.99E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 319 1.0E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 Gene3D G3DSA:1.10.287.130 231 318 2.6E-8 T 29-03-2018 CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 Gene3D G3DSA:3.30.565.10 324 478 8.6E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 SUPERFAMILY SSF47384 246 319 1.08E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 SMART SM00388 254 323 9.8E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS17950 b12955abd76421884ec667cb00977ce0 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 473 1.7E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS20500 4b7278c4fffc49a60638db897d0dea26 170 Gene3D G3DSA:1.10.10.10 3 161 1.5E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20500 4b7278c4fffc49a60638db897d0dea26 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 134 154 1.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20500 4b7278c4fffc49a60638db897d0dea26 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 84 1.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20500 4b7278c4fffc49a60638db897d0dea26 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 100 1.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20500 4b7278c4fffc49a60638db897d0dea26 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 120 1.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20500 4b7278c4fffc49a60638db897d0dea26 170 SUPERFAMILY SSF46785 23 156 1.15E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20500 4b7278c4fffc49a60638db897d0dea26 170 SMART SM00347 43 144 1.1E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20500 4b7278c4fffc49a60638db897d0dea26 170 Pfam PF01047 MarR family 50 108 2.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 SMART SM00642 22 421 5.1E-98 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 Gene3D G3DSA:3.90.1200.10 856 1124 1.1E-14 T 29-03-2018 CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 Gene3D G3DSA:3.20.20.80 19 468 1.1E-121 T 29-03-2018 CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 14 549 1.2E-280 T 29-03-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 SUPERFAMILY SSF56112 767 1124 1.06E-13 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 Pfam PF16657 Maltogenic Amylase, C-terminal domain 469 546 9.8E-30 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 SUPERFAMILY SSF51445 359 466 2.11E-127 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 SUPERFAMILY SSF51445 13 332 2.11E-127 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 Gene3D G3DSA:2.60.40.1180 469 559 1.2E-27 T 29-03-2018 CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 Pfam PF00128 Alpha amylase, catalytic domain 37 390 2.8E-71 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 TIGRFAM TIGR02457 TreS_Cterm: putative maltokinase 565 1119 1.5E-155 T 29-03-2018 IPR012811 Trehalose synthase/probable maltokinase, C-terminal domain CVS48_RS18390 50381a14258a4e2924abf2ec38425562 1136 SUPERFAMILY SSF51011 475 549 1.58E-18 T 29-03-2018 CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 Gene3D G3DSA:3.40.50.2300 70 180 3.5E-25 T 29-03-2018 CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 SMART SM00354 13 83 2.9E-23 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 Gene3D G3DSA:1.10.260.40 28 69 5.2E-19 T 29-03-2018 CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 29-03-2018 CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 Gene3D G3DSA:3.40.50.2300 181 341 1.2E-39 T 29-03-2018 CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 SUPERFAMILY SSF47413 13 71 2.53E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 1.3E-15 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 Gene3D G3DSA:1.10.10.10 7 27 3.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 Pfam PF13377 Periplasmic binding protein-like domain 181 341 6.8E-30 T 29-03-2018 CVS48_RS15055 ac8ae42e1977da0b4778b94f1c6737b8 341 SUPERFAMILY SSF53822 70 329 2.36E-54 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 237 375 1.1E-67 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 3.1E-40 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 Gene3D G3DSA:3.30.300.10 13 137 5.4E-44 T 29-03-2018 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 120 130 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 Gene3D G3DSA:3.30.300.10 250 387 7.2E-49 T 29-03-2018 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 SUPERFAMILY SSF55973 237 385 2.79E-67 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 387 56.807 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 263 271 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 386 6.2E-182 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 PIRSF PIRSF000497 1 387 1.3E-170 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 SUPERFAMILY SSF55973 114 236 3.02E-52 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 SUPERFAMILY SSF55973 5 112 1.77E-45 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 Gene3D G3DSA:3.30.300.10 138 237 4.8E-43 T 29-03-2018 CVS48_RS07315 c769cf42c576b1be7b7ff192d2059a88 387 Pfam PF02772 S-adenosylmethionine synthetase, central domain 119 235 1.6E-45 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 Gene3D G3DSA:3.30.450.20 228 282 8.9E-4 T 29-03-2018 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 Gene3D G3DSA:3.30.450.20 283 340 0.014 T 29-03-2018 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 Pfam PF00512 His Kinase A (phospho-acceptor) domain 352 418 4.8E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 SMART SM00387 463 569 3.4E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 Gene3D G3DSA:1.10.287.130 341 417 5.7E-7 T 29-03-2018 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 Pfam PF08448 PAS fold 114 223 8.4E-16 T 29-03-2018 IPR013656 PAS fold-4 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 SUPERFAMILY SSF55874 410 569 4.02E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 Gene3D G3DSA:3.30.565.10 422 580 8.4E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 Gene3D G3DSA:3.30.450.20 90 227 1.9E-28 T 29-03-2018 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 Pfam PF13188 PAS domain 233 283 0.011 T 29-03-2018 IPR000014 PAS domain CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 516 5.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 547 5.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 528 5.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 566 5.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 SMART SM00091 105 172 1.1E-8 T 29-03-2018 IPR000014 PAS domain CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 SMART SM00091 233 304 49.0 T 29-03-2018 IPR000014 PAS domain CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 SMART SM00086 179 221 4.8E-4 T 29-03-2018 IPR001610 PAC motif CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 106 228 1.5E-24 T 29-03-2018 IPR000014 PAS domain CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 464 566 1.4E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 SMART SM00388 351 421 3.9E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 SUPERFAMILY SSF47384 339 418 1.14E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 SUPERFAMILY SSF55785 95 219 6.28E-24 T 29-03-2018 IPR000014 PAS domain CVS48_RS16675 11feea5c819e528dd8b0d751a322400e 584 SUPERFAMILY SSF55785 218 327 6.11E-8 T 29-03-2018 IPR000014 PAS domain CVS48_RS05515 b59935b98a670e05336b3417c39aa2c2 393 Gene3D G3DSA:3.40.47.10 2 268 1.6E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS05515 b59935b98a670e05336b3417c39aa2c2 393 SUPERFAMILY SSF53901 5 270 1.84E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS05515 b59935b98a670e05336b3417c39aa2c2 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 8.9E-90 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS05515 b59935b98a670e05336b3417c39aa2c2 393 SUPERFAMILY SSF53901 271 392 7.6E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS05515 b59935b98a670e05336b3417c39aa2c2 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 6.7E-41 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS05515 b59935b98a670e05336b3417c39aa2c2 393 Gene3D G3DSA:3.40.47.10 269 390 3.5E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS05515 b59935b98a670e05336b3417c39aa2c2 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 3.5E-126 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS05515 b59935b98a670e05336b3417c39aa2c2 393 PIRSF PIRSF000429 1 393 9.8E-114 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS05515 b59935b98a670e05336b3417c39aa2c2 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CVS48_RS04405 4136e50224446da67d31c44543bfa199 116 SUPERFAMILY SSF54292 2 92 2.61E-21 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS04405 4136e50224446da67d31c44543bfa199 116 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS04405 4136e50224446da67d31c44543bfa199 116 Gene3D G3DSA:3.10.20.30 1 110 8.5E-24 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS04405 4136e50224446da67d31c44543bfa199 116 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 85 1.5E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS23880 2b934841b7907d0fe074d5a8b8b6ea03 565 SUPERFAMILY SSF56801 21 552 1.57E-147 T 29-03-2018 CVS48_RS23880 2b934841b7907d0fe074d5a8b8b6ea03 565 Gene3D G3DSA:3.30.300.30 454 558 2.2E-26 T 29-03-2018 CVS48_RS23880 2b934841b7907d0fe074d5a8b8b6ea03 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 469 543 2.4E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS23880 2b934841b7907d0fe074d5a8b8b6ea03 565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS23880 2b934841b7907d0fe074d5a8b8b6ea03 565 Gene3D G3DSA:3.40.50.980 21 215 2.0E-41 T 29-03-2018 CVS48_RS23880 2b934841b7907d0fe074d5a8b8b6ea03 565 Pfam PF00501 AMP-binding enzyme 30 460 3.7E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS23880 2b934841b7907d0fe074d5a8b8b6ea03 565 Gene3D G3DSA:3.40.50.980 216 370 1.8E-38 T 29-03-2018 CVS48_RS23880 2b934841b7907d0fe074d5a8b8b6ea03 565 Gene3D G3DSA:2.30.38.10 371 453 7.5E-26 T 29-03-2018 CVS48_RS17050 1644f7e14092f45db5790d3ac615708e 388 Gene3D G3DSA:1.20.140.10 222 388 1.1E-46 T 29-03-2018 CVS48_RS17050 1644f7e14092f45db5790d3ac615708e 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 219 1.9E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS17050 1644f7e14092f45db5790d3ac615708e 388 Gene3D G3DSA:1.10.540.10 1 123 3.8E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS17050 1644f7e14092f45db5790d3ac615708e 388 SUPERFAMILY SSF47203 231 386 1.42E-47 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS17050 1644f7e14092f45db5790d3ac615708e 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 2.3E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS17050 1644f7e14092f45db5790d3ac615708e 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 365 1.9E-37 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS17050 1644f7e14092f45db5790d3ac615708e 388 Gene3D G3DSA:2.40.110.10 124 221 6.4E-30 T 29-03-2018 CVS48_RS17050 1644f7e14092f45db5790d3ac615708e 388 SUPERFAMILY SSF56645 1 246 3.27E-65 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Pfam PF01739 CheR methyltransferase, SAM binding domain 282 470 4.5E-43 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Gene3D G3DSA:3.40.50.180 2 192 6.6E-50 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Gene3D G3DSA:1.10.287.620 646 733 6.8E-6 T 29-03-2018 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Pfam PF01339 CheB methylesterase 10 187 6.1E-39 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Pfam PF03705 CheR methyltransferase, all-alpha domain 219 267 5.1E-7 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Gene3D G3DSA:3.40.50.150 280 477 4.3E-36 T 29-03-2018 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Gene3D G3DSA:3.30.450.20 511 631 4.6E-4 T 29-03-2018 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Gene3D G3DSA:1.10.155.10 215 277 5.3E-9 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 SMART SM00138 214 475 6.6E-58 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 SUPERFAMILY SSF52738 5 190 2.35E-42 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 PRINTS PR00996 Glutamate methyltransferase family signature 349 365 9.1E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 PRINTS PR00996 Glutamate methyltransferase family signature 415 429 9.1E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 PRINTS PR00996 Glutamate methyltransferase family signature 273 285 9.1E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 PRINTS PR00996 Glutamate methyltransferase family signature 434 457 9.1E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 PRINTS PR00996 Glutamate methyltransferase family signature 313 333 9.1E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 SUPERFAMILY SSF47757 219 282 6.8E-7 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 SUPERFAMILY SSF53335 280 474 3.27E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 SUPERFAMILY SSF55785 721 837 5.58E-7 T 29-03-2018 IPR000014 PAS domain CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Gene3D G3DSA:3.30.450.20 734 873 1.0E-13 T 29-03-2018 CVS48_RS05570 8440cd90e10a087d2723000a1945473c 931 Pfam PF13596 PAS domain 731 837 4.6E-21 T 29-03-2018 CVS48_RS20295 c65301640e2519cb9c96361646585b6e 477 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 465 3.5E-121 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS20295 c65301640e2519cb9c96361646585b6e 477 Pfam PF02321 Outer membrane efflux protein 64 254 3.3E-25 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS20295 c65301640e2519cb9c96361646585b6e 477 Pfam PF02321 Outer membrane efflux protein 281 463 1.3E-30 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS20295 c65301640e2519cb9c96361646585b6e 477 Gene3D G3DSA:1.20.1600.10 22 470 2.3E-95 T 29-03-2018 CVS48_RS20295 c65301640e2519cb9c96361646585b6e 477 SUPERFAMILY SSF56954 2 468 8.63E-111 T 29-03-2018 CVS48_RS04640 09face5afdedb4f2414876d453b3f06c 263 Gene3D G3DSA:3.40.50.150 23 258 7.4E-26 T 29-03-2018 CVS48_RS04640 09face5afdedb4f2414876d453b3f06c 263 SUPERFAMILY SSF53335 28 241 2.98E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS04640 09face5afdedb4f2414876d453b3f06c 263 Pfam PF01564 Spermine/spermidine synthase domain 60 201 1.7E-10 T 29-03-2018 CVS48_RS22595 8f3a9295363b83153d39c2ad4eb9cfcc 350 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 142 345 3.2E-38 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS22595 8f3a9295363b83153d39c2ad4eb9cfcc 350 Gene3D G3DSA:3.90.850.10 117 349 3.8E-48 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS22595 8f3a9295363b83153d39c2ad4eb9cfcc 350 SUPERFAMILY SSF55331 2 124 1.15E-31 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CVS48_RS22595 8f3a9295363b83153d39c2ad4eb9cfcc 350 Gene3D G3DSA:3.30.429.10 1 116 3.3E-35 T 29-03-2018 CVS48_RS22595 8f3a9295363b83153d39c2ad4eb9cfcc 350 SUPERFAMILY SSF56529 138 345 1.2E-46 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS22595 8f3a9295363b83153d39c2ad4eb9cfcc 350 TIGRFAM TIGR02305 HpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit 141 344 1.5E-75 T 29-03-2018 IPR012686 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit GO:0008704|GO:0018800 KEGG: 00350+5.3.3.10+4.1.1.68 CVS48_RS22595 8f3a9295363b83153d39c2ad4eb9cfcc 350 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 120 8.9E-14 T 29-03-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 CVS48_RS12365 d33aab8010c3b1a11420469e0e94f4ca 451 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 387 2.6E-46 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS12365 d33aab8010c3b1a11420469e0e94f4ca 451 Pfam PF01554 MatE 246 395 2.5E-20 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS12365 d33aab8010c3b1a11420469e0e94f4ca 451 Pfam PF01554 MatE 16 175 2.9E-20 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS12365 d33aab8010c3b1a11420469e0e94f4ca 451 PIRSF PIRSF006603 1 447 5.1E-69 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS25470 d55ce6389c8724c30b104405b5cc4395 540 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 184 502 3.9E-21 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal CVS48_RS25470 d55ce6389c8724c30b104405b5cc4395 540 Pfam PF08479 POTRA domain, ShlB-type 48 121 9.9E-16 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type CVS48_RS25470 d55ce6389c8724c30b104405b5cc4395 540 Gene3D G3DSA:2.40.160.50 152 540 3.6E-51 T 29-03-2018 CVS48_RS25470 d55ce6389c8724c30b104405b5cc4395 540 Gene3D G3DSA:3.10.20.310 53 121 1.0E-12 T 29-03-2018 CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 SUPERFAMILY SSF52540 2 256 3.32E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 Pfam PF00005 ABC transporter 20 178 3.5E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 Pfam PF00005 ABC transporter 290 440 7.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 SUPERFAMILY SSF52540 271 512 6.69E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 SMART SM00382 299 498 3.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 SMART SM00382 28 228 3.3E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 Gene3D G3DSA:3.40.50.300 269 539 4.8E-72 T 29-03-2018 CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 Gene3D G3DSA:3.40.50.300 1 268 4.7E-68 T 29-03-2018 CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 492 518 0.002 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS13390 470393db8c31badaa88f48d3a81ef24e 539 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 269 5.6E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS04170 3b35abc306fd1e25672a3f6885f993e5 229 Gene3D G3DSA:3.40.1080.10 4 214 2.8E-52 T 29-03-2018 CVS48_RS04170 3b35abc306fd1e25672a3f6885f993e5 229 SUPERFAMILY SSF100950 5 214 9.77E-59 T 29-03-2018 CVS48_RS04170 3b35abc306fd1e25672a3f6885f993e5 229 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 5 210 7.1E-83 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CVS48_RS04170 3b35abc306fd1e25672a3f6885f993e5 229 SMART SM00882 7 204 2.8E-56 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS04170 3b35abc306fd1e25672a3f6885f993e5 229 Pfam PF01144 Coenzyme A transferase 7 183 2.9E-31 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS04170 3b35abc306fd1e25672a3f6885f993e5 229 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 45 53 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS10785 e37001c0039eadd8b699aea1e2debdad 631 Pfam PF00884 Sulfatase 272 537 2.9E-39 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CVS48_RS10785 e37001c0039eadd8b699aea1e2debdad 631 Gene3D G3DSA:3.40.720.10 260 543 7.5E-49 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS10785 e37001c0039eadd8b699aea1e2debdad 631 SUPERFAMILY SSF53649 269 580 3.14E-65 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS10785 e37001c0039eadd8b699aea1e2debdad 631 PIRSF PIRSF005091 8 623 4.0E-88 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Gene3D G3DSA:3.30.70.20 214 238 7.8E-5 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 PIRSF PIRSF036643 18 954 0.0 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Gene3D G3DSA:3.30.70.20 144 178 0.0032 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Gene3D G3DSA:3.40.50.740 300 511 7.6E-50 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Pfam PF00037 4Fe-4S binding domain 211 226 2.9E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 SUPERFAMILY SSF50692 768 923 1.56E-41 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Gene3D G3DSA:2.40.40.20 793 943 4.3E-34 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Gene3D G3DSA:3.30.70.20 179 213 2.3E-8 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Gene3D G3DSA:3.10.20.30 18 134 1.8E-18 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 SUPERFAMILY SSF53706 241 771 2.88E-193 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Gene3D G3DSA:2.20.25.90 239 299 4.6E-16 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 SUPERFAMILY SSF54292 22 95 1.24E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Gene3D G3DSA:3.40.50.740 512 780 6.0E-79 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 SMART SM00929 104 144 9.9E-19 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 97 8.1E-23 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Pfam PF00384 Molybdopterin oxidoreductase 297 728 2.0E-74 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 241 292 2.7E-16 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 213 224 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 104 143 8.5E-17 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 245 920 3.5E-285 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 SUPERFAMILY SSF54862 96 233 3.6E-38 T 29-03-2018 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 Pfam PF01568 Molydopterin dinucleotide binding domain 812 916 1.0E-27 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CVS48_RS12820 d8d32774d9814207845b4edb98312c2c 958 SMART SM00926 240 294 3.1E-16 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 SUPERFAMILY SSF82866 321 512 1.05E-33 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 SUPERFAMILY SSF82693 580 682 7.06E-7 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 Pfam PF00873 AcrB/AcrD/AcrF family 30 1032 2.9E-160 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 PRINTS PR00702 Acriflavin resistance protein family signature 486 509 4.1E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 PRINTS PR00702 Acriflavin resistance protein family signature 62 80 4.1E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 PRINTS PR00702 Acriflavin resistance protein family signature 354 377 4.1E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 4.1E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 PRINTS PR00702 Acriflavin resistance protein family signature 408 432 4.1E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 PRINTS PR00702 Acriflavin resistance protein family signature 566 583 4.1E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 Gene3D G3DSA:3.30.70.1430 64 168 1.1E-28 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 SUPERFAMILY SSF82693 64 159 4.19E-17 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 Gene3D G3DSA:3.30.70.1430 581 739 1.4E-13 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 Gene3D G3DSA:1.20.1640.10 823 1037 3.9E-34 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 SUPERFAMILY SSF82693 160 206 6.28E-16 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 SUPERFAMILY SSF82693 292 342 6.28E-16 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 Gene3D G3DSA:3.30.2090.10 740 818 3.3E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 SUPERFAMILY SSF82714 209 289 1.12E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 SUPERFAMILY SSF82866 816 1039 4.58E-47 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 Gene3D G3DSA:1.20.1640.10 306 525 4.1E-32 T 29-03-2018 CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 SUPERFAMILY SSF82714 734 817 1.31E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS28795 020423f594d9dfffa38758eccc03f25c 1062 Gene3D G3DSA:3.30.2090.10 205 291 1.2E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 Pfam PF05199 GMC oxidoreductase 387 525 2.6E-41 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 SUPERFAMILY SSF51905 472 534 8.91E-93 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 SUPERFAMILY SSF51905 1 288 8.91E-93 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 Gene3D G3DSA:3.40.50.720 2 40 8.3E-4 T 29-03-2018 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 Gene3D G3DSA:3.30.560.10 105 488 4.5E-110 T 29-03-2018 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 PIRSF PIRSF000137 1 541 7.3E-153 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 254 268 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 SUPERFAMILY SSF54373 290 473 6.77E-59 T 29-03-2018 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 Gene3D G3DSA:4.10.450.10 41 104 3.2E-30 T 29-03-2018 CVS48_RS20285 f9551ebcfe301a4937a73312cd829b07 545 Pfam PF00732 GMC oxidoreductase 5 295 3.3E-91 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS01650 b3f7c9adce35f60c50bc23a465288dad 269 SUPERFAMILY SSF46785 20 89 1.04E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01650 b3f7c9adce35f60c50bc23a465288dad 269 SUPERFAMILY SSF55781 73 253 1.44E-47 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS01650 b3f7c9adce35f60c50bc23a465288dad 269 Pfam PF01614 Bacterial transcriptional regulator 133 243 1.4E-25 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS01650 b3f7c9adce35f60c50bc23a465288dad 269 Gene3D G3DSA:3.30.450.40 87 262 6.0E-49 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS01650 b3f7c9adce35f60c50bc23a465288dad 269 Gene3D G3DSA:1.10.10.10 7 76 2.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01650 b3f7c9adce35f60c50bc23a465288dad 269 Pfam PF09339 IclR helix-turn-helix domain 22 68 2.1E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS01650 b3f7c9adce35f60c50bc23a465288dad 269 SMART SM00346 17 105 3.4E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SUPERFAMILY SSF52540 358 471 1.65E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 Pfam PF03461 TRCF domain 1018 1111 3.5E-26 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SUPERFAMILY SSF143517 1003 1153 1.1E-37 T 29-03-2018 CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SMART SM00487 609 799 7.2E-32 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1119 28.058 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 Pfam PF02559 CarD-like/TRCF domain 489 584 1.4E-25 T 29-03-2018 IPR003711 CarD-like/TRCF domain CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SMART SM00982 1017 1117 1.3E-47 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 Pfam PF00270 DEAD/DEAH box helicase 617 771 1.7E-16 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SUPERFAMILY SSF52540 792 999 2.15E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SUPERFAMILY SSF52540 532 792 1.13E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SMART SM01058 488 585 8.6E-46 T 29-03-2018 IPR003711 CarD-like/TRCF domain CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SUPERFAMILY SSF141259 480 557 8.5E-23 T 29-03-2018 IPR003711 CarD-like/TRCF domain CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 162 1090 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SUPERFAMILY SSF52540 30 354 1.42E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 SMART SM00490 835 919 1.2E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 Gene3D G3DSA:3.40.50.300 797 965 3.2E-26 T 29-03-2018 CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 Gene3D G3DSA:3.40.50.300 368 790 1.1E-37 T 29-03-2018 CVS48_RS28620 d6e36c3a7c3e079baf526646e372b416 1154 Pfam PF00271 Helicase conserved C-terminal domain 814 918 2.4E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 SMART SM00881 8 103 1.2E-30 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 Gene3D G3DSA:3.40.50.720 4 128 5.8E-33 T 29-03-2018 CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 Pfam PF13549 ATP-grasp domain 478 689 1.7E-61 T 29-03-2018 CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 Pfam PF13380 CoA binding domain 13 137 2.3E-20 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 Gene3D G3DSA:3.40.50.261 129 304 6.8E-32 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 Gene3D G3DSA:3.40.50.261 305 450 9.5E-26 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 SUPERFAMILY SSF56059 477 690 1.25E-36 T 29-03-2018 CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 160 297 8.5E-43 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 SUPERFAMILY SSF51735 5 140 3.94E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 SUPERFAMILY SSF52210 306 449 6.15E-25 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 Gene3D G3DSA:3.30.470.20 538 690 6.1E-40 T 29-03-2018 CVS48_RS23415 47ef5f3733674ecf3a46cd019f961dac 694 SUPERFAMILY SSF52210 158 296 2.62E-32 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS03710 667b03ee5144d9cc9e0d2988d53ca9b4 443 SUPERFAMILY SSF56954 28 439 7.59E-82 T 29-03-2018 CVS48_RS03710 667b03ee5144d9cc9e0d2988d53ca9b4 443 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 25 439 2.7E-89 T 29-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 CVS48_RS03710 667b03ee5144d9cc9e0d2988d53ca9b4 443 Gene3D G3DSA:1.20.1600.10 25 432 8.2E-62 T 29-03-2018 CVS48_RS03710 667b03ee5144d9cc9e0d2988d53ca9b4 443 Pfam PF02321 Outer membrane efflux protein 239 423 1.4E-23 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS03710 667b03ee5144d9cc9e0d2988d53ca9b4 443 Pfam PF02321 Outer membrane efflux protein 30 215 5.2E-21 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS20460 d83e387e45cfdd96d53ba10fd305fedc 329 Pfam PF00892 EamA-like transporter family 3 111 6.6E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS20460 d83e387e45cfdd96d53ba10fd305fedc 329 SUPERFAMILY SSF103481 223 309 5.23E-5 T 29-03-2018 CVS48_RS25890 e7fa40845f58d8f98a50b5db0d304195 394 PIRSF PIRSF000429 1 393 6.2E-62 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS25890 e7fa40845f58d8f98a50b5db0d304195 394 SUPERFAMILY SSF53901 186 391 7.44E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS25890 e7fa40845f58d8f98a50b5db0d304195 394 SUPERFAMILY SSF53901 7 117 7.44E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS25890 e7fa40845f58d8f98a50b5db0d304195 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 78 96 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CVS48_RS25890 e7fa40845f58d8f98a50b5db0d304195 394 Gene3D G3DSA:3.40.47.10 1 242 2.7E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS25890 e7fa40845f58d8f98a50b5db0d304195 394 Pfam PF02803 Thiolase, C-terminal domain 272 362 4.7E-9 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS25890 e7fa40845f58d8f98a50b5db0d304195 394 Pfam PF00108 Thiolase, N-terminal domain 9 193 2.5E-16 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS25890 e7fa40845f58d8f98a50b5db0d304195 394 ProSitePatterns PS00737 Thiolases signature 2. 333 349 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CVS48_RS25890 e7fa40845f58d8f98a50b5db0d304195 394 Gene3D G3DSA:3.40.47.10 263 386 9.2E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS08430 640a749bae085e92f54c4df6045c3644 253 Gene3D G3DSA:1.20.58.430 29 220 6.1E-14 T 29-03-2018 CVS48_RS08430 640a749bae085e92f54c4df6045c3644 253 SUPERFAMILY SSF101082 29 212 1.03E-6 T 29-03-2018 IPR023220 Type IV secretion system, VirB5-domain CVS48_RS08235 c61182f480149ea55004752f8afab8d1 107 Pfam PF13663 Domain of unknown function (DUF4148) 5 72 2.1E-9 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 SUPERFAMILY SSF81923 4 140 4.91E-37 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Gene3D G3DSA:1.10.1780.10 1 150 1.7E-37 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Gene3D G3DSA:3.40.50.300 561 773 5.2E-49 T 29-03-2018 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Gene3D G3DSA:1.10.8.60 774 868 1.9E-22 T 29-03-2018 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 SMART SM01086 774 863 2.5E-35 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Pfam PF07724 AAA domain (Cdc48 subfamily) 605 768 1.2E-55 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 610 628 2.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 717 731 2.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 655 673 2.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 684 702 2.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 SUPERFAMILY SSF52540 555 863 1.65E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 SMART SM00382 606 775 8.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 SMART SM00382 197 343 1.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 334 5.3E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Gene3D G3DSA:3.40.50.300 156 341 4.8E-25 T 29-03-2018 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 863 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Gene3D G3DSA:1.10.8.60 342 556 4.5E-45 T 29-03-2018 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 640 658 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 774 852 1.2E-24 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 SUPERFAMILY SSF52540 158 519 1.96E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.1E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS22705 0ed0af7ed112a4374542d81717ddc989 868 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 144 7.7E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS11595 532e144dee0105cf2b205152af30fcf4 227 Gene3D G3DSA:3.50.30.40 20 194 2.1E-52 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS11595 532e144dee0105cf2b205152af30fcf4 227 SUPERFAMILY SSF89562 24 182 1.26E-46 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS11595 532e144dee0105cf2b205152af30fcf4 227 Pfam PF03737 Aldolase/RraA 29 174 8.6E-44 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS07260 77bc1562ddda327a3e8b7a2adc0c9718 167 Pfam PF01475 Ferric uptake regulator family 27 145 4.4E-16 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CVS48_RS07260 77bc1562ddda327a3e8b7a2adc0c9718 167 Gene3D G3DSA:1.10.10.10 6 98 8.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07260 77bc1562ddda327a3e8b7a2adc0c9718 167 SUPERFAMILY SSF46785 21 150 1.43E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 3.8E-121 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 Gene3D G3DSA:1.20.272.10 243 362 2.2E-5 T 29-03-2018 CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 SUPERFAMILY SSF52540 34 224 4.08E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 Gene3D G3DSA:1.10.8.60 167 242 8.3E-16 T 29-03-2018 CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 SUPERFAMILY SSF48019 243 360 5.44E-22 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 Gene3D G3DSA:3.40.50.300 2 166 1.6E-38 T 29-03-2018 CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 664 779 5.5E-5 T 29-03-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 SMART SM00382 37 179 4.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.2E-37 T 29-03-2018 CVS48_RS13725 0cf38e57b71b9b3eddb33989af8333dd 792 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 367 5.4E-18 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CVS48_RS07915 b28c5c90ef5bfe83e967013c947b1bcd 195 Gene3D G3DSA:3.40.50.450 1 191 4.2E-61 T 29-03-2018 CVS48_RS07915 b28c5c90ef5bfe83e967013c947b1bcd 195 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 4 177 2.9E-59 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CVS48_RS07915 b28c5c90ef5bfe83e967013c947b1bcd 195 SUPERFAMILY SSF102405 3 176 1.83E-61 T 29-03-2018 CVS48_RS07915 b28c5c90ef5bfe83e967013c947b1bcd 195 Pfam PF03641 Possible lysine decarboxylase 48 176 4.5E-44 T 29-03-2018 IPR031100 LOG family CVS48_RS06210 81113aaca2e156eabe2429c361e0b06e 462 Gene3D G3DSA:3.40.309.10 249 443 4.3E-57 T 29-03-2018 CVS48_RS06210 81113aaca2e156eabe2429c361e0b06e 462 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 230 237 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS06210 81113aaca2e156eabe2429c361e0b06e 462 Pfam PF00171 Aldehyde dehydrogenase family 4 456 2.1E-124 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS06210 81113aaca2e156eabe2429c361e0b06e 462 SUPERFAMILY SSF53720 5 460 4.19E-130 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS06210 81113aaca2e156eabe2429c361e0b06e 462 Gene3D G3DSA:3.40.605.10 2 248 3.7E-73 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 Gene3D G3DSA:3.30.70.920 52 148 1.6E-23 T 29-03-2018 CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 SUPERFAMILY SSF46785 1 60 6.75E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 Pfam PF01037 Lrp/AsnC ligand binding domain 67 140 2.3E-23 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 Gene3D G3DSA:1.10.10.10 2 51 6.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 6.6E-18 T 29-03-2018 CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 SMART SM00344 1 109 6.5E-43 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS03105 2b2ad0fdc8e156e089d00ef531dd2250 149 SUPERFAMILY SSF54909 64 149 2.68E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS12835 668ad31b1abf10986261c2c556167489 359 SUPERFAMILY SSF53850 187 343 1.85E-11 T 29-03-2018 CVS48_RS12835 668ad31b1abf10986261c2c556167489 359 Gene3D G3DSA:3.40.190.10 219 296 1.7E-6 T 29-03-2018 CVS48_RS12835 668ad31b1abf10986261c2c556167489 359 SUPERFAMILY SSF46785 27 144 1.09E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12835 668ad31b1abf10986261c2c556167489 359 Gene3D G3DSA:1.10.10.10 20 114 7.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12835 668ad31b1abf10986261c2c556167489 359 Pfam PF12727 PBP superfamily domain 154 328 1.8E-48 T 29-03-2018 IPR024370 PBP domain CVS48_RS12835 668ad31b1abf10986261c2c556167489 359 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 29 87 2.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12835 668ad31b1abf10986261c2c556167489 359 Gene3D G3DSA:3.40.190.10 122 218 0.23 T 29-03-2018 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 Gene3D G3DSA:3.40.50.2300 2 127 7.7E-30 T 29-03-2018 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 SMART SM00421 147 204 7.3E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 Pfam PF00072 Response regulator receiver domain 6 116 1.4E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 SUPERFAMILY SSF52172 3 133 1.85E-30 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 SUPERFAMILY SSF46894 135 209 6.8E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 SMART SM00448 3 116 3.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 Gene3D G3DSA:1.10.10.10 128 211 2.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 9.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 9.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 9.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25395 675c9363e822d1b784db50da63bf6f1f 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 4.1E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12600 b6f91e0370f8aadfd73501bec1d0abb6 319 Pfam PF12889 Protein of unknown function (DUF3829) 39 315 1.9E-42 T 29-03-2018 IPR024291 Protein of unknown function DUF3829 CVS48_RS09620 034ca8414ef5a7fecee0f2c0596222b9 409 Pfam PF01979 Amidohydrolase family 54 402 4.5E-36 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS09620 034ca8414ef5a7fecee0f2c0596222b9 409 Gene3D G3DSA:3.20.20.140 70 361 1.3E-40 T 29-03-2018 CVS48_RS09620 034ca8414ef5a7fecee0f2c0596222b9 409 Gene3D G3DSA:2.30.40.10 1 69 1.5E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS09620 034ca8414ef5a7fecee0f2c0596222b9 409 SUPERFAMILY SSF51338 365 402 1.3E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS09620 034ca8414ef5a7fecee0f2c0596222b9 409 SUPERFAMILY SSF51338 4 58 1.3E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS09620 034ca8414ef5a7fecee0f2c0596222b9 409 SUPERFAMILY SSF51556 58 363 4.7E-85 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 5.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 Gene3D G3DSA:1.10.10.10 6 88 3.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 SUPERFAMILY SSF53850 92 293 2.9E-37 T 29-03-2018 CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 Pfam PF03466 LysR substrate binding domain 90 291 1.9E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 Gene3D G3DSA:3.40.190.10 174 263 1.7E-19 T 29-03-2018 CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 Gene3D G3DSA:3.40.190.10 92 173 2.5E-9 T 29-03-2018 CVS48_RS26610 3424d05519b02dde7a92679a047c8fa6 308 SUPERFAMILY SSF46785 3 83 6.91E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Gene3D G3DSA:3.10.20.310 184 275 4.6E-23 T 29-03-2018 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Gene3D G3DSA:3.10.20.310 101 183 7.6E-12 T 29-03-2018 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 33 777 2.0E-268 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Gene3D G3DSA:2.40.160.50 388 777 1.3E-80 T 29-03-2018 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 10 777 25.554 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Gene3D G3DSA:3.10.20.310 29 100 1.2E-12 T 29-03-2018 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Pfam PF07244 Surface antigen variable number repeat 185 272 5.2E-19 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Pfam PF07244 Surface antigen variable number repeat 275 352 1.8E-11 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Pfam PF07244 Surface antigen variable number repeat 101 181 1.2E-9 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Pfam PF07244 Surface antigen variable number repeat 34 99 9.3E-7 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Pfam PF07244 Surface antigen variable number repeat 356 430 9.2E-15 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 PIRSF PIRSF006076 2 777 6.8E-250 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Gene3D G3DSA:3.10.20.310 276 355 1.3E-13 T 29-03-2018 CVS48_RS17160 6665ec42aeddc691c630b30727fa5feb 777 Pfam PF01103 Surface antigen 457 777 6.8E-68 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 PIRSF PIRSF002144 1 91 1.1E-33 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 SUPERFAMILY SSF54570 2 84 1.83E-36 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 1.7E-46 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 Gene3D G3DSA:3.30.860.10 1 91 1.2E-41 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.976 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.6E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.6E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.6E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 Pfam PF00203 Ribosomal protein S19 3 83 1.3E-37 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06405 4940cfa76f79a52700673051b99ce02d 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS15950 be949db5584956a8b3ef4421e35f7a5b 310 SUPERFAMILY SSF52402 3 186 1.19E-49 T 29-03-2018 CVS48_RS15950 be949db5584956a8b3ef4421e35f7a5b 310 Pfam PF01012 Electron transfer flavoprotein domain 3 169 4.3E-36 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS15950 be949db5584956a8b3ef4421e35f7a5b 310 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 191 273 9.9E-36 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CVS48_RS15950 be949db5584956a8b3ef4421e35f7a5b 310 Gene3D G3DSA:3.40.50.1220 186 310 7.9E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS15950 be949db5584956a8b3ef4421e35f7a5b 310 PIRSF PIRSF000089 1 310 4.8E-105 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CVS48_RS15950 be949db5584956a8b3ef4421e35f7a5b 310 SMART SM00893 3 183 5.1E-44 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS15950 be949db5584956a8b3ef4421e35f7a5b 310 SUPERFAMILY SSF52467 190 309 4.46E-47 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS15950 be949db5584956a8b3ef4421e35f7a5b 310 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 254 280 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CVS48_RS15950 be949db5584956a8b3ef4421e35f7a5b 310 Gene3D G3DSA:3.40.50.620 1 184 6.7E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS04590 4456d3daa4c7ef3bf79b018de898498c 365 Pfam PF00563 EAL domain 80 314 4.6E-57 T 29-03-2018 IPR001633 EAL domain CVS48_RS04590 4456d3daa4c7ef3bf79b018de898498c 365 SUPERFAMILY SSF141868 80 321 6.54E-64 T 29-03-2018 IPR001633 EAL domain CVS48_RS04590 4456d3daa4c7ef3bf79b018de898498c 365 SMART SM00052 74 319 4.1E-62 T 29-03-2018 IPR001633 EAL domain CVS48_RS04590 4456d3daa4c7ef3bf79b018de898498c 365 Gene3D G3DSA:3.20.20.450 76 331 1.7E-68 T 29-03-2018 IPR001633 EAL domain CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.6E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.6E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.6E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 Gene3D G3DSA:3.40.190.10 177 267 8.0E-17 T 29-03-2018 CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 SUPERFAMILY SSF53850 90 295 2.34E-37 T 29-03-2018 CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 Gene3D G3DSA:3.40.190.10 90 176 3.6E-26 T 29-03-2018 CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 SUPERFAMILY SSF46785 4 87 5.09E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 3.6E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 Gene3D G3DSA:1.10.10.10 2 88 1.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04620 66d7044019b7c652ca540ce390863466 322 Pfam PF03466 LysR substrate binding domain 89 293 1.2E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 329 398 1.7E-17 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 109 4.5E-15 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 SUPERFAMILY SSF56014 408 562 1.7E-34 T 29-03-2018 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 SUPERFAMILY SSF56014 120 281 3.79E-46 T 29-03-2018 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 SUPERFAMILY SSF55124 1 125 2.45E-29 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 Gene3D G3DSA:3.30.413.10 405 580 1.4E-31 T 29-03-2018 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 Gene3D G3DSA:3.90.480.10 213 404 2.7E-31 T 29-03-2018 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 Gene3D G3DSA:3.90.480.10 49 203 2.2E-19 T 29-03-2018 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 SUPERFAMILY SSF55124 251 275 9.16E-27 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 SUPERFAMILY SSF55124 315 421 9.16E-27 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 411 562 6.9E-8 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS09140 b102a7819444dda08437b6f02df4dae6 580 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 271 8.8E-40 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 Gene3D G3DSA:3.10.290.10 103 146 9.3E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 SMART SM01390 3 96 6.2E-49 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 Pfam PF01479 S4 domain 98 144 6.1E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 Gene3D G3DSA:1.10.1050.10 147 207 7.4E-15 T 29-03-2018 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 SMART SM00363 97 161 3.5E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 6.3E-32 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 Gene3D G3DSA:1.10.1050.10 1 102 1.1E-43 T 29-03-2018 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 SUPERFAMILY SSF55174 3 207 1.18E-66 T 29-03-2018 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 34.738 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CVS48_RS06565 1ee80096358708fd0e4951cb4051d93f 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 2.4E-78 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CVS48_RS07130 c2ba1a4deee5bc80457ecb42ff830d7b 363 SUPERFAMILY SSF53383 9 361 1.6E-114 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS07130 c2ba1a4deee5bc80457ecb42ff830d7b 363 PIRSF PIRSF000390 1 363 1.3E-105 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CVS48_RS07130 c2ba1a4deee5bc80457ecb42ff830d7b 363 Gene3D G3DSA:3.40.640.10 1 237 1.6E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS07130 c2ba1a4deee5bc80457ecb42ff830d7b 363 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 358 6.3E-126 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CVS48_RS07130 c2ba1a4deee5bc80457ecb42ff830d7b 363 Gene3D G3DSA:3.90.1150.10 238 363 2.0E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS06710 4ce775a3bb7e3b89476c883055376067 189 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 21 167 1.8E-43 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN CVS48_RS06710 4ce775a3bb7e3b89476c883055376067 189 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 31 158 1.7E-40 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 253 2.2E-60 T 29-03-2018 CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 Gene3D G3DSA:3.40.50.10090 3 51 4.5E-9 T 29-03-2018 CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.1E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.1E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 2.1E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 180 9.9E-5 T 29-03-2018 CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 Gene3D G3DSA:3.40.50.720 52 256 1.5E-61 T 29-03-2018 CVS48_RS08900 427b5a61664d15b2f61867fda1901490 256 SUPERFAMILY SSF51735 6 254 1.35E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS27765 2e58db1d7551d3a7acc556b5674a2491 349 Gene3D G3DSA:3.40.50.300 2 251 1.4E-76 T 29-03-2018 CVS48_RS27765 2e58db1d7551d3a7acc556b5674a2491 349 Gene3D G3DSA:2.40.50.140 277 340 7.9E-6 T 29-03-2018 CVS48_RS27765 2e58db1d7551d3a7acc556b5674a2491 349 Pfam PF00005 ABC transporter 19 160 1.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS27765 2e58db1d7551d3a7acc556b5674a2491 349 Pfam PF08402 TOBE domain 276 347 2.7E-9 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS27765 2e58db1d7551d3a7acc556b5674a2491 349 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS27765 2e58db1d7551d3a7acc556b5674a2491 349 SMART SM00382 27 210 2.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS27765 2e58db1d7551d3a7acc556b5674a2491 349 SUPERFAMILY SSF52540 3 242 2.55E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27765 2e58db1d7551d3a7acc556b5674a2491 349 SUPERFAMILY SSF50331 236 346 2.89E-10 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS12595 df8563a3157f43757ccdd0be99739f9d 294 SMART SM00478 137 294 4.1E-12 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CVS48_RS12595 df8563a3157f43757ccdd0be99739f9d 294 Gene3D G3DSA:1.10.1670.10 261 294 6.2E-6 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CVS48_RS12595 df8563a3157f43757ccdd0be99739f9d 294 SMART SM01009 11 127 1.5E-56 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CVS48_RS12595 df8563a3157f43757ccdd0be99739f9d 294 SUPERFAMILY SSF55945 12 108 2.51E-28 T 29-03-2018 CVS48_RS12595 df8563a3157f43757ccdd0be99739f9d 294 Pfam PF06029 AlkA N-terminal domain 12 127 4.1E-39 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CVS48_RS12595 df8563a3157f43757ccdd0be99739f9d 294 SUPERFAMILY SSF48150 117 291 1.54E-37 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CVS48_RS12595 df8563a3157f43757ccdd0be99739f9d 294 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 134 282 2.0E-8 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CVS48_RS12595 df8563a3157f43757ccdd0be99739f9d 294 Gene3D G3DSA:3.30.310.20 11 112 4.8E-39 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CVS48_RS12595 df8563a3157f43757ccdd0be99739f9d 294 Gene3D G3DSA:1.10.340.30 113 260 1.8E-27 T 29-03-2018 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 Gene3D G3DSA:1.10.287.130 129 182 1.1E-11 T 29-03-2018 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 SMART SM00091 1 66 1.2E-4 T 29-03-2018 IPR000014 PAS domain CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 Pfam PF00512 His Kinase A (phospho-acceptor) domain 125 180 3.4E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 Gene3D G3DSA:3.30.565.10 187 352 5.5E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 SMART SM00387 229 352 3.2E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 Gene3D G3DSA:3.30.450.20 3 128 1.3E-13 T 29-03-2018 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 SUPERFAMILY SSF55874 191 350 1.57E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 SUPERFAMILY SSF55785 6 68 6.11E-8 T 29-03-2018 IPR000014 PAS domain CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 Pfam PF00989 PAS fold 4 89 4.0E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 SUPERFAMILY SSF47384 110 181 9.22E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 312 4.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 331 4.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 349 4.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 4.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 229 351 4.6E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 112 4.2E-7 T 29-03-2018 IPR000014 PAS domain CVS48_RS19475 26a12113f66891838c9bb97e4fd885eb 354 SMART SM00388 124 189 3.4E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS26500 566df3743a065116a2c0a8e8adea26f8 110 Pfam PF05957 Bacterial protein of unknown function (DUF883) 16 106 5.0E-23 T 29-03-2018 IPR010279 Protein of unknown function DUF883, ElaB CVS48_RS21020 92cd073796f766e27bee97bd515ed9ae 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 304 9.7E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS21020 92cd073796f766e27bee97bd515ed9ae 305 SUPERFAMILY SSF161098 97 289 6.41E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS21020 92cd073796f766e27bee97bd515ed9ae 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 17 72 3.8E-11 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS21020 92cd073796f766e27bee97bd515ed9ae 305 Gene3D G3DSA:1.10.3720.10 17 294 6.1E-47 T 29-03-2018 CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 217 1.7E-61 T 29-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 Pfam PF03379 CcmB protein 6 218 5.1E-64 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 8.8E-64 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 8.8E-64 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 194 217 8.8E-64 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 134 157 8.8E-64 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 157 176 8.8E-64 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 8.8E-64 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 8.8E-64 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15740 b99d1fffc019d7634e4b876efc9dfe4e 221 PIRSF PIRSF002764 1 221 4.9E-72 T 29-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria CVS48_RS23935 5afc40d544f9eb7b2ff62511f341bbad 355 SUPERFAMILY SSF111369 42 104 1.7E-6 T 29-03-2018 CVS48_RS23935 5afc40d544f9eb7b2ff62511f341bbad 355 SUPERFAMILY SSF111369 172 299 6.02E-6 T 29-03-2018 CVS48_RS23935 5afc40d544f9eb7b2ff62511f341bbad 355 Gene3D G3DSA:2.40.50.100 47 118 4.4E-12 T 29-03-2018 CVS48_RS23935 5afc40d544f9eb7b2ff62511f341bbad 355 Pfam PF13437 HlyD family secretion protein 215 320 1.3E-13 T 29-03-2018 CVS48_RS23935 5afc40d544f9eb7b2ff62511f341bbad 355 Gene3D G3DSA:1.10.287.470 119 176 9.2E-10 T 29-03-2018 CVS48_RS23935 5afc40d544f9eb7b2ff62511f341bbad 355 Gene3D G3DSA:2.40.50.100 199 249 2.2E-6 T 29-03-2018 CVS48_RS23935 5afc40d544f9eb7b2ff62511f341bbad 355 Pfam PF13533 Biotin-lipoyl like 49 93 1.2E-5 T 29-03-2018 CVS48_RS06680 dfb6349c75b61b1c20ddf82c540c933e 646 Pfam PF05947 Type VI secretion system, TssF 6 644 2.7E-219 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CVS48_RS06680 dfb6349c75b61b1c20ddf82c540c933e 646 PIRSF PIRSF028304 1 646 2.2E-198 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CVS48_RS06680 dfb6349c75b61b1c20ddf82c540c933e 646 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 5 645 4.1E-193 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 192 256 6.3E-12 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 SUPERFAMILY SSF49584 160 258 3.92E-12 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 SUPERFAMILY SSF49354 40 166 4.97E-41 T 29-03-2018 IPR008962 PapD-like CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 PRINTS PR00969 Pili chaperone signature 187 202 1.7E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 PRINTS PR00969 Pili chaperone signature 123 140 1.7E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 PRINTS PR00969 Pili chaperone signature 45 54 1.7E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 PRINTS PR00969 Pili chaperone signature 94 115 1.7E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 PRINTS PR00969 Pili chaperone signature 148 163 1.7E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 45 166 1.1E-42 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 122 139 - T 29-03-2018 IPR018046 Pili assembly chaperone, conserved site CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 Gene3D G3DSA:2.60.40.10 168 260 2.2E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS04155 31fda7634a22eb3f17a77366eaa10a55 265 Gene3D G3DSA:2.60.40.10 44 167 3.2E-36 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS18540 edd4b12f7ae18c4838e6f53226485bd6 669 Gene3D G3DSA:3.40.50.10070 277 403 6.6E-19 T 29-03-2018 CVS48_RS18540 edd4b12f7ae18c4838e6f53226485bd6 669 Gene3D G3DSA:1.25.40.10 418 491 0.001 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS18540 edd4b12f7ae18c4838e6f53226485bd6 669 Gene3D G3DSA:1.25.40.10 162 276 0.14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS18540 edd4b12f7ae18c4838e6f53226485bd6 669 Gene3D G3DSA:1.25.40.10 492 663 5.3E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS18540 edd4b12f7ae18c4838e6f53226485bd6 669 SUPERFAMILY SSF48452 435 640 1.06E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS18540 edd4b12f7ae18c4838e6f53226485bd6 669 Gene3D G3DSA:1.10.10.10 11 103 3.8E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20340 c19b80aa84bb2e790717343749cf7659 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 303 8.2E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20340 c19b80aa84bb2e790717343749cf7659 305 SUPERFAMILY SSF161098 88 286 7.85E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20340 c19b80aa84bb2e790717343749cf7659 305 Gene3D G3DSA:1.10.3720.10 4 292 3.2E-41 T 29-03-2018 CVS48_RS18165 77af8abad32b4db468f242abc4eda03b 528 Gene3D G3DSA:1.20.1250.20 208 498 4.4E-19 T 29-03-2018 CVS48_RS18165 77af8abad32b4db468f242abc4eda03b 528 Pfam PF05977 Transmembrane secretion effector 1 515 2.7E-207 T 29-03-2018 IPR010290 Transmembrane secretion effector CVS48_RS18165 77af8abad32b4db468f242abc4eda03b 528 SUPERFAMILY SSF103473 6 393 1.44E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS18165 77af8abad32b4db468f242abc4eda03b 528 Gene3D G3DSA:1.20.1250.20 2 199 1.5E-23 T 29-03-2018 CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 TIGRFAM TIGR00498 lexA: repressor LexA 3 212 8.4E-71 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 SUPERFAMILY SSF51306 90 211 3.66E-35 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 126 136 4.7E-10 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 137 148 4.7E-10 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 165 177 4.7E-10 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 SUPERFAMILY SSF46785 4 70 2.72E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 Pfam PF01726 LexA DNA binding domain 3 66 1.0E-28 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 Gene3D G3DSA:1.10.10.10 3 69 3.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 Hamap MF_00015 LexA repressor [lexA]. 4 213 32.095 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 Pfam PF00717 Peptidase S24-like 129 194 1.1E-15 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CVS48_RS21955 d6760b2df96b76a42ada3449e38ba52f 216 Gene3D G3DSA:2.10.109.10 95 213 7.0E-25 T 29-03-2018 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 SMART SM00963 43 119 2.5E-16 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 Pfam PF00448 SRP54-type protein, GTPase domain 134 336 6.1E-66 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 Gene3D G3DSA:1.20.120.140 245 338 2.5E-23 T 29-03-2018 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 Pfam PF02881 SRP54-type protein, helical bundle domain 53 113 1.1E-9 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 Gene3D G3DSA:3.40.50.300 110 244 2.1E-19 T 29-03-2018 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 SMART SM00382 132 310 4.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 SMART SM00962 133 337 6.1E-103 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 SUPERFAMILY SSF47364 38 112 7.59E-18 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 SUPERFAMILY SSF52540 126 336 1.5E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 62 337 57.082 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 Gene3D G3DSA:1.20.120.140 6 109 7.5E-19 T 29-03-2018 CVS48_RS10980 f99fe89e92923cd9e8deed29a16fbdf7 338 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 62 335 2.6E-95 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 12 694 1.7E-303 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 SUPERFAMILY SSF51445 507 584 1.08E-119 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 SUPERFAMILY SSF51445 150 478 1.08E-119 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 SUPERFAMILY SSF51011 598 695 7.55E-15 T 29-03-2018 CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 16 104 2.7E-16 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 Gene3D G3DSA:2.60.40.10 11 147 1.7E-44 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 SMART SM00642 151 577 1.9E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 SUPERFAMILY SSF81296 12 155 9.8E-45 T 29-03-2018 IPR014756 Immunoglobulin E-set CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 Gene3D G3DSA:2.60.40.1180 590 698 9.2E-18 T 29-03-2018 CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 Pfam PF00128 Alpha amylase, catalytic domain 201 285 1.1E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18380 2dd3585dd8cc427fa69926bef950d7d8 703 Gene3D G3DSA:3.20.20.80 149 589 5.8E-104 T 29-03-2018 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 SUPERFAMILY SSF63380 100 193 1.07E-23 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 Gene3D G3DSA:2.40.30.10 98 192 1.3E-19 T 29-03-2018 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 Pfam PF00970 Oxidoreductase FAD-binding domain 105 195 2.7E-11 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 294 302 2.6E-12 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 229 238 2.6E-12 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 145 152 2.6E-12 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 129 139 2.6E-12 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 241 252 2.6E-12 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 204 223 2.6E-12 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 Gene3D G3DSA:3.10.20.30 1 97 7.6E-22 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 Gene3D G3DSA:3.40.50.80 193 332 2.4E-30 T 29-03-2018 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 Pfam PF00175 Oxidoreductase NAD-binding domain 205 308 2.8E-27 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 SUPERFAMILY SSF54292 1 92 2.49E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 80 3.8E-15 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 SUPERFAMILY SSF52343 197 328 1.02E-39 T 29-03-2018 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 145 152 4.6E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 129 141 4.6E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 229 238 4.6E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 294 302 4.6E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 204 223 4.6E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS04375 9ba3ba084ce6a1807ab5a6ba61c1503c 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 188 197 4.6E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 377 386 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 250 265 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 SUPERFAMILY SSF46689 407 460 8.06E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 SUPERFAMILY SSF52172 23 209 6.69E-40 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 Pfam PF00072 Response regulator receiver domain 25 134 1.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 188 201 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 Gene3D G3DSA:3.40.50.300 158 335 7.1E-24 T 29-03-2018 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 Gene3D G3DSA:1.10.10.60 417 461 1.7E-13 T 29-03-2018 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 SMART SM00382 184 327 9.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 SUPERFAMILY SSF52540 164 393 1.24E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 SMART SM00448 23 134 9.4E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 Pfam PF02954 Bacterial regulatory protein, Fis family 417 457 2.9E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 Gene3D G3DSA:3.40.50.2300 12 155 2.5E-30 T 29-03-2018 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 Pfam PF00158 Sigma-54 interaction domain 165 330 4.6E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CVS48_RS14305 b6c237029ed222815c6cbe1c52e053c6 468 Gene3D G3DSA:1.10.8.60 336 416 4.5E-20 T 29-03-2018 CVS48_RS01080 935ba8c0005ae4e99eb1e346e781c58d 142 Pfam PF08334 Type II secretion system (T2SS), protein G 38 137 1.1E-34 T 29-03-2018 IPR013545 Type II secretion system protein G CVS48_RS01080 935ba8c0005ae4e99eb1e346e781c58d 142 Pfam PF07963 Prokaryotic N-terminal methylation motif 13 33 3.7E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS01080 935ba8c0005ae4e99eb1e346e781c58d 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 51 69 3.8E-12 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CVS48_RS01080 935ba8c0005ae4e99eb1e346e781c58d 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 15 40 3.8E-12 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CVS48_RS01080 935ba8c0005ae4e99eb1e346e781c58d 142 SUPERFAMILY SSF54523 42 137 1.15E-28 T 29-03-2018 CVS48_RS01080 935ba8c0005ae4e99eb1e346e781c58d 142 Gene3D G3DSA:3.30.700.10 30 140 2.0E-22 T 29-03-2018 CVS48_RS01080 935ba8c0005ae4e99eb1e346e781c58d 142 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 34 1.4E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS01080 935ba8c0005ae4e99eb1e346e781c58d 142 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 14 137 3.6E-44 T 29-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 CVS48_RS06815 2df2e310ac135fc1efffb255100e3319 299 Pfam PF03466 LysR substrate binding domain 91 295 1.1E-47 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS06815 2df2e310ac135fc1efffb255100e3319 299 Gene3D G3DSA:3.40.190.10 178 266 1.2E-27 T 29-03-2018 CVS48_RS06815 2df2e310ac135fc1efffb255100e3319 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 1.2E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS06815 2df2e310ac135fc1efffb255100e3319 299 SUPERFAMILY SSF53850 92 297 1.27E-50 T 29-03-2018 CVS48_RS06815 2df2e310ac135fc1efffb255100e3319 299 Gene3D G3DSA:1.10.10.10 6 89 3.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06815 2df2e310ac135fc1efffb255100e3319 299 SUPERFAMILY SSF46785 9 113 2.35E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06815 2df2e310ac135fc1efffb255100e3319 299 Gene3D G3DSA:3.40.190.10 90 177 1.2E-15 T 29-03-2018 CVS48_RS01815 5e9dd02218227f8937abd0e248b8a447 313 Pfam PF01715 IPP transferase 38 286 3.2E-87 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CVS48_RS01815 5e9dd02218227f8937abd0e248b8a447 313 SUPERFAMILY SSF52540 5 146 1.53E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01815 5e9dd02218227f8937abd0e248b8a447 313 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 4 288 3.1E-91 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CVS48_RS01815 5e9dd02218227f8937abd0e248b8a447 313 Gene3D G3DSA:1.10.287.890 201 283 9.2E-26 T 29-03-2018 CVS48_RS01815 5e9dd02218227f8937abd0e248b8a447 313 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 4 303 29.51 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CVS48_RS01815 5e9dd02218227f8937abd0e248b8a447 313 Gene3D G3DSA:3.40.50.300 1 195 1.1E-61 T 29-03-2018 CVS48_RS15945 230c4b5ab752011bdd26152f1136065e 249 SMART SM00893 23 211 7.9E-65 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS15945 230c4b5ab752011bdd26152f1136065e 249 SUPERFAMILY SSF52402 1 242 1.95E-83 T 29-03-2018 CVS48_RS15945 230c4b5ab752011bdd26152f1136065e 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CVS48_RS15945 230c4b5ab752011bdd26152f1136065e 249 PIRSF PIRSF000090 1 249 9.4E-83 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CVS48_RS15945 230c4b5ab752011bdd26152f1136065e 249 Pfam PF01012 Electron transfer flavoprotein domain 30 200 2.4E-47 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS15945 230c4b5ab752011bdd26152f1136065e 249 Gene3D G3DSA:3.40.50.620 1 248 1.0E-84 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS27505 0bf3ea2e768c012d8ef600cdcdfa5ca6 440 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 440 33.023 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CVS48_RS27505 0bf3ea2e768c012d8ef600cdcdfa5ca6 440 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CVS48_RS27505 0bf3ea2e768c012d8ef600cdcdfa5ca6 440 Gene3D G3DSA:3.65.10.10 24 233 8.4E-60 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS27505 0bf3ea2e768c012d8ef600cdcdfa5ca6 440 Gene3D G3DSA:3.65.10.10 234 439 8.4E-56 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS27505 0bf3ea2e768c012d8ef600cdcdfa5ca6 440 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 18 438 4.4E-134 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CVS48_RS27505 0bf3ea2e768c012d8ef600cdcdfa5ca6 440 ProSitePatterns PS00885 EPSP synthase signature 2. 350 368 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CVS48_RS27505 0bf3ea2e768c012d8ef600cdcdfa5ca6 440 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 15 433 1.6E-117 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS27505 0bf3ea2e768c012d8ef600cdcdfa5ca6 440 SUPERFAMILY SSF55205 11 437 1.44E-119 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CVS48_RS27505 0bf3ea2e768c012d8ef600cdcdfa5ca6 440 PIRSF PIRSF000505 8 440 9.2E-134 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 Hamap MF_02004 Valine--tRNA ligase [valS]. 19 963 15.388 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 SUPERFAMILY SSF47323 660 913 2.8E-60 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 Gene3D G3DSA:1.10.287.380 892 961 7.0E-21 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 SUPERFAMILY SSF46589 898 962 5.13E-17 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 SUPERFAMILY SSF50677 212 375 7.98E-57 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 SUPERFAMILY SSF52374 375 589 9.73E-132 T 29-03-2018 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 SUPERFAMILY SSF52374 627 659 9.73E-132 T 29-03-2018 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 SUPERFAMILY SSF52374 19 213 9.73E-132 T 29-03-2018 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 Gene3D G3DSA:3.40.50.620 20 637 8.5E-132 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 64 75 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 649 5.7E-201 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 TIGRFAM TIGR00422 valS: valine--tRNA ligase 20 944 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 PRINTS PR00986 Valyl-tRNA synthetase signature 524 542 5.9E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 PRINTS PR00986 Valyl-tRNA synthetase signature 57 68 5.9E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 PRINTS PR00986 Valyl-tRNA synthetase signature 264 281 5.9E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 PRINTS PR00986 Valyl-tRNA synthetase signature 493 514 5.9E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 PRINTS PR00986 Valyl-tRNA synthetase signature 380 393 5.9E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 898 963 3.4E-21 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 Pfam PF08264 Anticodon-binding domain of tRNA 691 843 3.8E-37 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CVS48_RS14675 5544feab41afcd70ca7596a6b0b46945 964 Gene3D G3DSA:1.10.730.10 638 811 3.0E-53 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS11355 069fc77a23909c0f0e1dfc6c406cae6d 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS11355 069fc77a23909c0f0e1dfc6c406cae6d 491 SUPERFAMILY SSF53720 3 482 1.44E-157 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS11355 069fc77a23909c0f0e1dfc6c406cae6d 491 Gene3D G3DSA:3.40.309.10 267 465 5.1E-69 T 29-03-2018 CVS48_RS11355 069fc77a23909c0f0e1dfc6c406cae6d 491 TIGRFAM TIGR03216 OH_muco_semi_DH: 2-hydroxymuconic semialdehyde dehydrogenase 4 483 1.4E-260 T 29-03-2018 IPR017628 2-hydroxymuconic semialdehyde dehydrogenase GO:0016620|GO:0055114 CVS48_RS11355 069fc77a23909c0f0e1dfc6c406cae6d 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS11355 069fc77a23909c0f0e1dfc6c406cae6d 491 Pfam PF00171 Aldehyde dehydrogenase family 13 479 1.7E-158 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS11355 069fc77a23909c0f0e1dfc6c406cae6d 491 Gene3D G3DSA:3.40.605.10 1 266 3.5E-91 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS07690 5f2f46fb3e4f774324bfc13e313bc19a 247 Pfam PF04972 BON domain 131 194 3.9E-10 T 29-03-2018 IPR007055 BON domain CVS48_RS07690 5f2f46fb3e4f774324bfc13e313bc19a 247 Pfam PF04972 BON domain 64 122 1.2E-11 T 29-03-2018 IPR007055 BON domain CVS48_RS07690 5f2f46fb3e4f774324bfc13e313bc19a 247 SMART SM00749 136 199 0.014 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria CVS48_RS07690 5f2f46fb3e4f774324bfc13e313bc19a 247 SMART SM00749 64 122 38.0 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria CVS48_RS07070 3a938caa669c410981bd00b06a133bc1 214 Gene3D G3DSA:2.160.10.10 91 214 6.1E-32 T 29-03-2018 CVS48_RS07070 3a938caa669c410981bd00b06a133bc1 214 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 146 9.2E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS07070 3a938caa669c410981bd00b06a133bc1 214 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 6 209 1.2E-70 T 29-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CVS48_RS07070 3a938caa669c410981bd00b06a133bc1 214 SUPERFAMILY SSF51161 4 211 7.9E-47 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS07070 3a938caa669c410981bd00b06a133bc1 214 Gene3D G3DSA:3.40.50.20 3 90 2.8E-17 T 29-03-2018 CVS48_RS07070 3a938caa669c410981bd00b06a133bc1 214 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 161 193 3.4E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS05730 77efa39cb60a8c47494c8baadc0b5f8f 352 Pfam PF09084 NMT1/THI5 like 51 269 4.3E-21 T 29-03-2018 IPR015168 SsuA/THI5-like CVS48_RS05730 77efa39cb60a8c47494c8baadc0b5f8f 352 Gene3D G3DSA:3.40.190.10 146 351 6.8E-21 T 29-03-2018 CVS48_RS05730 77efa39cb60a8c47494c8baadc0b5f8f 352 Gene3D G3DSA:3.40.190.10 33 145 3.3E-9 T 29-03-2018 CVS48_RS05730 77efa39cb60a8c47494c8baadc0b5f8f 352 SUPERFAMILY SSF53850 41 276 1.36E-31 T 29-03-2018 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 PIRSF PIRSF036426 1 466 5.1E-191 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 218 428 7.2E-51 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Gene3D G3DSA:3.40.1010.10 216 341 2.6E-38 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 SUPERFAMILY SSF53790 215 458 6.41E-78 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Gene3D G3DSA:3.40.50.720 1 105 4.3E-20 T 29-03-2018 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Gene3D G3DSA:3.30.160.110 106 147 4.9E-16 T 29-03-2018 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Pfam PF14824 Sirohaem biosynthesis protein central 124 145 1.2E-6 T 29-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 SUPERFAMILY SSF51735 1 112 3.25E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Gene3D G3DSA:1.10.8.210 151 208 5.1E-18 T 29-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 SUPERFAMILY SSF75615 114 208 4.05E-24 T 29-03-2018 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 221 235 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 5.0E-72 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Gene3D G3DSA:3.30.950.10 342 463 1.7E-41 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 216 450 8.3E-90 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Pfam PF13241 Putative NAD(P)-binding 6 115 7.0E-26 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 297 330 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Pfam PF10414 Sirohaem synthase dimerisation region 151 207 1.9E-17 T 29-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS13030 4cd9cd0a7c8ba3cadc46822c7d5849c4 468 Hamap MF_01646 Siroheme synthase [cysG]. 1 461 48.99 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CVS48_RS19885 00bb6ca8bdc96fa6fe0fcd90a767efb5 369 Gene3D G3DSA:3.50.30.60 220 367 5.8E-42 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CVS48_RS19885 00bb6ca8bdc96fa6fe0fcd90a767efb5 369 Pfam PF02016 LD-carboxypeptidase 77 351 1.3E-72 T 29-03-2018 IPR003507 Peptidase family S66 CVS48_RS19885 00bb6ca8bdc96fa6fe0fcd90a767efb5 369 SUPERFAMILY SSF141986 206 357 1.57E-42 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CVS48_RS19885 00bb6ca8bdc96fa6fe0fcd90a767efb5 369 SUPERFAMILY SSF52317 76 223 2.93E-31 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS19885 00bb6ca8bdc96fa6fe0fcd90a767efb5 369 Gene3D G3DSA:3.40.50.10740 69 219 4.1E-41 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CVS48_RS19885 00bb6ca8bdc96fa6fe0fcd90a767efb5 369 PIRSF PIRSF028757 68 368 7.9E-72 T 29-03-2018 IPR003507 Peptidase family S66 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 Gene3D G3DSA:3.30.2090.10 181 269 3.5E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 Gene3D G3DSA:3.30.70.1430 40 142 2.2E-26 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 Gene3D G3DSA:1.20.1640.10 281 499 6.1E-49 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 Gene3D G3DSA:1.20.1640.10 805 1025 2.4E-34 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 Pfam PF00873 AcrB/AcrD/AcrF family 6 1013 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82714 183 266 5.62E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82693 40 134 3.14E-23 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82693 136 182 1.02E-21 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82693 268 324 1.02E-21 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82693 558 654 3.19E-16 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 Gene3D G3DSA:3.30.2090.10 706 792 1.5E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82866 815 1015 9.29E-42 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 Gene3D G3DSA:3.30.70.1430 560 656 5.8E-16 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 8.8E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 8.8E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 8.8E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 8.8E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 8.8E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 PRINTS PR00702 Acriflavin resistance protein family signature 609 623 8.8E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 8.8E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 8.8E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 8.8E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82714 706 789 9.16E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82693 792 837 2.88E-9 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82693 669 705 2.88E-9 T 29-03-2018 CVS48_RS03540 af8b9eb14919a8ef008c80ad0dcdf6aa 1037 SUPERFAMILY SSF82866 291 491 9.55E-48 T 29-03-2018 CVS48_RS06720 14d1d571ff303be20ff4a735272d37f3 428 Pfam PF09850 Type VI secretion system protein DotU 38 240 1.3E-76 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU CVS48_RS06720 14d1d571ff303be20ff4a735272d37f3 428 TIGRFAM TIGR03350 type_VI_ompA: type VI secretion system peptidoglycan-associated domain 276 412 1.1E-53 T 29-03-2018 IPR017733 Type VI secretion system peptidoglycan-associated domain CVS48_RS06720 14d1d571ff303be20ff4a735272d37f3 428 SUPERFAMILY SSF103088 281 412 9.81E-29 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS06720 14d1d571ff303be20ff4a735272d37f3 428 Pfam PF00691 OmpA family 309 406 1.9E-17 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS06720 14d1d571ff303be20ff4a735272d37f3 428 Gene3D G3DSA:3.30.1330.60 262 423 1.3E-33 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS06720 14d1d571ff303be20ff4a735272d37f3 428 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 37 247 3.5E-78 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 Gene3D G3DSA:1.10.10.10 100 162 1.8E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 Pfam PF04542 Sigma-70 region 2 7 71 4.8E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 Gene3D G3DSA:1.10.1740.10 3 99 4.6E-15 T 29-03-2018 CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 SUPERFAMILY SSF54427 172 288 8.56E-13 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 161 2.6E-17 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 Pfam PF08281 Sigma-70, region 4 108 159 6.4E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 7 287 1.9E-97 T 29-03-2018 IPR014303 RNA polymerase sigma-70, ECF type CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 SUPERFAMILY SSF88659 102 161 5.79E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 SUPERFAMILY SSF88946 6 85 1.53E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS11750 dc11d23aaccf144ed6190807fab99a11 294 Gene3D G3DSA:3.10.450.50 163 293 9.7E-13 T 29-03-2018 CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 Gene3D G3DSA:3.40.50.10090 7 54 9.4E-11 T 29-03-2018 CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 4.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 199 2.1E-4 T 29-03-2018 CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 Gene3D G3DSA:3.40.50.720 55 259 8.3E-63 T 29-03-2018 CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 SUPERFAMILY SSF51735 10 257 8.24E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 2.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26755 fbb19ce1d76e2d545ddd9f78beef8e55 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 255 1.1E-64 T 29-03-2018 CVS48_RS12255 0ccff5c8550f5440858c691826466655 303 Gene3D G3DSA:1.20.120.530 152 299 1.9E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS12255 0ccff5c8550f5440858c691826466655 303 Pfam PF07729 FCD domain 163 286 1.0E-17 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS12255 0ccff5c8550f5440858c691826466655 303 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 64 1.1E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS12255 0ccff5c8550f5440858c691826466655 303 SUPERFAMILY SSF48008 157 293 1.2E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS12255 0ccff5c8550f5440858c691826466655 303 Gene3D G3DSA:1.10.10.10 2 71 1.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12255 0ccff5c8550f5440858c691826466655 303 SUPERFAMILY SSF46785 8 67 3.14E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12255 0ccff5c8550f5440858c691826466655 303 Gene3D G3DSA:1.10.10.10 84 151 0.016 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12255 0ccff5c8550f5440858c691826466655 303 SMART SM00895 162 287 1.5E-10 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS12255 0ccff5c8550f5440858c691826466655 303 SMART SM00345 7 65 1.5E-4 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18360 b21b9f4580b1b88963a65881d6787bb2 735 Pfam PF00593 TonB dependent receptor 293 734 1.8E-44 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS18360 b21b9f4580b1b88963a65881d6787bb2 735 Gene3D G3DSA:2.40.170.20 196 735 1.3E-76 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS18360 b21b9f4580b1b88963a65881d6787bb2 735 Pfam PF07715 TonB-dependent Receptor Plug Domain 84 184 4.8E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS18360 b21b9f4580b1b88963a65881d6787bb2 735 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 86 734 4.6E-107 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS18360 b21b9f4580b1b88963a65881d6787bb2 735 SUPERFAMILY SSF56935 38 735 3.33E-125 T 29-03-2018 CVS48_RS18360 b21b9f4580b1b88963a65881d6787bb2 735 Gene3D G3DSA:2.170.130.10 40 193 2.1E-24 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS22725 c16b172be4fd23058d5e07aeccfb4b9a 157 SUPERFAMILY SSF46785 1 105 1.67E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22725 c16b172be4fd23058d5e07aeccfb4b9a 157 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.2E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS22725 c16b172be4fd23058d5e07aeccfb4b9a 157 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.2E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS22725 c16b172be4fd23058d5e07aeccfb4b9a 157 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.2E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS22725 c16b172be4fd23058d5e07aeccfb4b9a 157 Gene3D G3DSA:1.10.10.10 2 97 1.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22725 c16b172be4fd23058d5e07aeccfb4b9a 157 SMART SM00418 11 85 7.4E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS22725 c16b172be4fd23058d5e07aeccfb4b9a 157 Pfam PF12840 Helix-turn-helix domain 10 69 4.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15125 134ed133d5f01fc58831db7760181182 184 SUPERFAMILY SSF54364 7 79 1.96E-28 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CVS48_RS15125 134ed133d5f01fc58831db7760181182 184 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 170 2.4E-39 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CVS48_RS15125 134ed133d5f01fc58831db7760181182 184 Gene3D G3DSA:3.30.110.10 81 179 3.1E-37 T 29-03-2018 CVS48_RS15125 134ed133d5f01fc58831db7760181182 184 SUPERFAMILY SSF55200 84 172 2.09E-34 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CVS48_RS15125 134ed133d5f01fc58831db7760181182 184 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 31.438 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CVS48_RS15125 134ed133d5f01fc58831db7760181182 184 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CVS48_RS15125 134ed133d5f01fc58831db7760181182 184 Gene3D G3DSA:3.10.20.80 4 80 1.4E-29 T 29-03-2018 CVS48_RS15125 134ed133d5f01fc58831db7760181182 184 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 172 1.1E-69 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CVS48_RS15125 134ed133d5f01fc58831db7760181182 184 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 78 4.7E-29 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CVS48_RS05765 0a0ac06910699c7bd11e339f31b86640 172 Pfam PF00856 SET domain 21 124 1.4E-18 T 29-03-2018 IPR001214 SET domain GO:0005515 CVS48_RS05765 0a0ac06910699c7bd11e339f31b86640 172 SMART SM00317 9 130 4.5E-26 T 29-03-2018 IPR001214 SET domain GO:0005515 CVS48_RS05765 0a0ac06910699c7bd11e339f31b86640 172 Gene3D G3DSA:2.170.270.10 5 153 8.2E-41 T 29-03-2018 CVS48_RS05765 0a0ac06910699c7bd11e339f31b86640 172 SUPERFAMILY SSF82199 8 150 6.41E-41 T 29-03-2018 CVS48_RS20085 002e9e6a670ec9ef3c43109bf662d5ca 243 SUPERFAMILY SSF52172 13 124 1.25E-7 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS20085 002e9e6a670ec9ef3c43109bf662d5ca 243 Gene3D G3DSA:3.40.50.2300 5 126 4.2E-8 T 29-03-2018 CVS48_RS20085 002e9e6a670ec9ef3c43109bf662d5ca 243 Gene3D G3DSA:1.10.10.10 138 243 2.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20085 002e9e6a670ec9ef3c43109bf662d5ca 243 SUPERFAMILY SSF46894 149 240 6.8E-10 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS20200 fe652e0242a972ad4bd46c2b85e0981d 496 PIRSF PIRSF006060 6 493 2.7E-82 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CVS48_RS20200 fe652e0242a972ad4bd46c2b85e0981d 496 Pfam PF00324 Amino acid permease 26 478 1.6E-131 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CVS48_RS20200 fe652e0242a972ad4bd46c2b85e0981d 496 ProSitePatterns PS00218 Amino acid permeases signature. 51 82 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CVS48_RS19710 c7775e13292fc4632bac2094a89319cf 327 Gene3D G3DSA:3.40.190.10 24 164 1.3E-20 T 29-03-2018 CVS48_RS19710 c7775e13292fc4632bac2094a89319cf 327 SUPERFAMILY SSF53850 22 321 3.21E-58 T 29-03-2018 CVS48_RS19710 c7775e13292fc4632bac2094a89319cf 327 Pfam PF13343 Bacterial extracellular solute-binding protein 90 285 2.1E-31 T 29-03-2018 CVS48_RS19710 c7775e13292fc4632bac2094a89319cf 327 PIRSF PIRSF002825 1 324 5.0E-73 T 29-03-2018 IPR026045 Ferric binding protein CVS48_RS19710 c7775e13292fc4632bac2094a89319cf 327 Gene3D G3DSA:3.40.190.10 165 319 2.4E-17 T 29-03-2018 CVS48_RS25790 18364713650217aab9f2359c0952f824 230 Pfam PF01339 CheB methylesterase 10 187 4.6E-46 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS25790 18364713650217aab9f2359c0952f824 230 SUPERFAMILY SSF52738 6 190 2.09E-45 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS25790 18364713650217aab9f2359c0952f824 230 Gene3D G3DSA:3.40.50.180 2 194 3.5E-54 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS00270 7044b93936434a73af037ab4f3ba0f4b 109 Pfam PF00893 Small Multidrug Resistance protein 1 93 4.8E-32 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CVS48_RS00270 7044b93936434a73af037ab4f3ba0f4b 109 SUPERFAMILY SSF103481 5 104 8.63E-21 T 29-03-2018 CVS48_RS03375 7d9a8a8789b93d3472172884aad434d8 177 SUPERFAMILY SSF54427 20 174 7.13E-45 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS03375 7d9a8a8789b93d3472172884aad434d8 177 Pfam PF00866 Ring hydroxylating beta subunit 33 165 1.0E-32 T 29-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CVS48_RS03375 7d9a8a8789b93d3472172884aad434d8 177 Gene3D G3DSA:3.10.450.50 19 177 6.1E-30 T 29-03-2018 CVS48_RS02845 26a5f1035b3baf5700c9e58f82fecaee 259 Pfam PF08241 Methyltransferase domain 80 131 4.8E-9 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CVS48_RS02845 26a5f1035b3baf5700c9e58f82fecaee 259 Gene3D G3DSA:3.40.50.150 24 225 2.7E-13 T 29-03-2018 CVS48_RS02845 26a5f1035b3baf5700c9e58f82fecaee 259 SUPERFAMILY SSF53335 79 200 3.83E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS11580 054d35b56ef8996c732039331898deee 306 PIRSF PIRSF017082 2 306 1.4E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11580 054d35b56ef8996c732039331898deee 306 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 33 302 9.7E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11580 054d35b56ef8996c732039331898deee 306 SUPERFAMILY SSF53850 87 268 5.43E-14 T 29-03-2018 CVS48_RS11580 054d35b56ef8996c732039331898deee 306 Gene3D G3DSA:3.40.190.10 109 215 8.0E-14 T 29-03-2018 CVS48_RS17905 d42c822b32c8833db791167cbfa15f0a 278 Pfam PF00005 ABC transporter 25 175 5.5E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS17905 d42c822b32c8833db791167cbfa15f0a 278 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS17905 d42c822b32c8833db791167cbfa15f0a 278 Gene3D G3DSA:3.40.50.300 6 272 8.1E-73 T 29-03-2018 CVS48_RS17905 d42c822b32c8833db791167cbfa15f0a 278 SUPERFAMILY SSF52540 9 245 3.1E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS17905 d42c822b32c8833db791167cbfa15f0a 278 SMART SM00382 34 231 2.5E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS17905 d42c822b32c8833db791167cbfa15f0a 278 PIRSF PIRSF039085 6 250 5.9E-99 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS28970 1046c31741c6a799322be5631c5ead0e 321 SUPERFAMILY SSF53850 111 269 2.34E-9 T 29-03-2018 CVS48_RS28970 1046c31741c6a799322be5631c5ead0e 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 317 4.0E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS28970 1046c31741c6a799322be5631c5ead0e 321 PIRSF PIRSF017082 4 321 6.5E-66 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS28970 1046c31741c6a799322be5631c5ead0e 321 Gene3D G3DSA:3.40.190.10 121 286 8.1E-13 T 29-03-2018 CVS48_RS14880 57dfdfb79449184e4e4c84f6cd92fced 498 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 7 484 43.508 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 CVS48_RS14880 57dfdfb79449184e4e4c84f6cd92fced 498 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 9 467 7.5E-135 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 CVS48_RS24880 f326b8d4c7a5a1ff1a56cd10049d43fc 578 SUPERFAMILY SSF53335 199 367 2.39E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS24880 f326b8d4c7a5a1ff1a56cd10049d43fc 578 Gene3D G3DSA:3.40.50.150 49 412 5.3E-9 T 29-03-2018 CVS48_RS19935 9626bf659fb36acab4467a7907ead154 328 SUPERFAMILY SSF53850 116 285 1.63E-9 T 29-03-2018 CVS48_RS19935 9626bf659fb36acab4467a7907ead154 328 PIRSF PIRSF017082 2 327 2.8E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS19935 9626bf659fb36acab4467a7907ead154 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 1.5E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS19935 9626bf659fb36acab4467a7907ead154 328 Gene3D G3DSA:3.40.190.10 160 295 3.8E-7 T 29-03-2018 CVS48_RS13165 6932ec324407563ce7a074403be0c187 314 Gene3D G3DSA:3.40.50.10750 119 275 2.5E-45 T 29-03-2018 CVS48_RS13165 6932ec324407563ce7a074403be0c187 314 Pfam PF01515 Phosphate acetyl/butaryl transferase 85 299 3.4E-44 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CVS48_RS13165 6932ec324407563ce7a074403be0c187 314 SUPERFAMILY SSF53659 9 304 3.91E-71 T 29-03-2018 CVS48_RS13165 6932ec324407563ce7a074403be0c187 314 PIRSF PIRSF000428 6 305 7.9E-88 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 Gene3D G3DSA:3.40.50.300 10 314 8.5E-74 T 29-03-2018 CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 Gene3D G3DSA:3.40.50.300 323 581 2.4E-76 T 29-03-2018 CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 SMART SM00382 42 240 2.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 SMART SM00382 356 548 4.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 Pfam PF00005 ABC transporter 34 190 1.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 Pfam PF00005 ABC transporter 348 498 2.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 SUPERFAMILY SSF52540 326 570 2.24E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 550 577 2.4E-5 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 274 7.5E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 SUPERFAMILY SSF52540 13 261 5.77E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS18310 12a1e6e0a6d91f1495ae5e895082bb1a 597 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS22745 7704ba057f5d760ccbc86c5531dedf51 110 SUPERFAMILY SSF54292 3 89 5.24E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS22745 7704ba057f5d760ccbc86c5531dedf51 110 Gene3D G3DSA:3.10.20.30 1 99 2.9E-20 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS22745 7704ba057f5d760ccbc86c5531dedf51 110 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 81 5.8E-13 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS03810 f4886de6499ff28ae0effa8774e5a617 332 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 297 1.6E-88 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CVS48_RS03810 f4886de6499ff28ae0effa8774e5a617 332 SUPERFAMILY SSF50891 195 303 6.07E-10 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS03810 f4886de6499ff28ae0effa8774e5a617 332 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 4 322 1.6E-90 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CVS48_RS03810 f4886de6499ff28ae0effa8774e5a617 332 SMART SM00797 24 314 6.2E-128 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CVS48_RS09870 0535422164f8aea76a05e9eccf48bd26 260 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 47 259 30.247 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CVS48_RS09870 0535422164f8aea76a05e9eccf48bd26 260 Pfam PF02390 Putative methyltransferase 86 254 3.6E-54 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CVS48_RS09870 0535422164f8aea76a05e9eccf48bd26 260 Gene3D G3DSA:3.40.50.150 53 260 8.0E-26 T 29-03-2018 CVS48_RS09870 0535422164f8aea76a05e9eccf48bd26 260 SUPERFAMILY SSF53335 41 258 4.01E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS09870 0535422164f8aea76a05e9eccf48bd26 260 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 81 259 2.2E-52 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CVS48_RS02665 eca022600707f31259bbf7d294206e00 190 PRINTS PR00502 NUDIX hydrolase family signature 33 47 9.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CVS48_RS02665 eca022600707f31259bbf7d294206e00 190 PRINTS PR00502 NUDIX hydrolase family signature 47 62 9.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CVS48_RS02665 eca022600707f31259bbf7d294206e00 190 SUPERFAMILY SSF55811 6 165 2.3E-31 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS02665 eca022600707f31259bbf7d294206e00 190 Gene3D G3DSA:3.90.79.10 1 164 4.8E-32 T 29-03-2018 CVS48_RS02665 eca022600707f31259bbf7d294206e00 190 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 38.077 T 29-03-2018 IPR022927 RNA pyrophosphohydrolase RppH CVS48_RS02665 eca022600707f31259bbf7d294206e00 190 Pfam PF00293 NUDIX domain 7 136 1.4E-23 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CVS48_RS02665 eca022600707f31259bbf7d294206e00 190 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CVS48_RS05245 f3d832c0330a6c8b048b616fa2bae2eb 327 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 4.6E-21 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CVS48_RS05245 f3d832c0330a6c8b048b616fa2bae2eb 327 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 155 234 6.1E-7 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CVS48_RS05245 f3d832c0330a6c8b048b616fa2bae2eb 327 Gene3D G3DSA:3.40.50.720 1 129 3.2E-36 T 29-03-2018 CVS48_RS05245 f3d832c0330a6c8b048b616fa2bae2eb 327 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 1 325 1.5E-125 T 29-03-2018 IPR030827 Inositol 2-dehydrogenase CVS48_RS05245 f3d832c0330a6c8b048b616fa2bae2eb 327 SUPERFAMILY SSF51735 2 143 2.36E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS05245 f3d832c0330a6c8b048b616fa2bae2eb 327 SUPERFAMILY SSF55347 123 285 5.76E-31 T 29-03-2018 CVS48_RS05245 f3d832c0330a6c8b048b616fa2bae2eb 327 Gene3D G3DSA:3.30.360.10 130 327 1.2E-41 T 29-03-2018 CVS48_RS19015 69d5c3ecb9adb11387eae4b17a4d09fc 360 Gene3D G3DSA:3.30.66.10 32 97 5.0E-34 T 29-03-2018 IPR035447 DNA topoisomerase I, N-terminal CVS48_RS19015 69d5c3ecb9adb11387eae4b17a4d09fc 360 Gene3D G3DSA:3.90.15.10 98 243 2.3E-35 T 29-03-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 CVS48_RS19015 69d5c3ecb9adb11387eae4b17a4d09fc 360 SUPERFAMILY SSF55869 39 99 2.22E-22 T 29-03-2018 IPR035447 DNA topoisomerase I, N-terminal CVS48_RS19015 69d5c3ecb9adb11387eae4b17a4d09fc 360 SUPERFAMILY SSF56349 95 318 6.47E-65 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS19015 69d5c3ecb9adb11387eae4b17a4d09fc 360 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 102 300 7.3E-27 T 29-03-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 CVS48_RS19015 69d5c3ecb9adb11387eae4b17a4d09fc 360 Gene3D G3DSA:1.20.120.380 250 326 6.7E-25 T 29-03-2018 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 CVS48_RS12625 c137bd4e8f64c2a5c08d7564a43b632a 731 Gene3D G3DSA:2.40.170.20 178 731 9.2E-63 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12625 c137bd4e8f64c2a5c08d7564a43b632a 731 Pfam PF00593 TonB dependent receptor 287 730 1.3E-40 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12625 c137bd4e8f64c2a5c08d7564a43b632a 731 SUPERFAMILY SSF56935 20 731 1.57E-115 T 29-03-2018 CVS48_RS12625 c137bd4e8f64c2a5c08d7564a43b632a 731 Gene3D G3DSA:2.170.130.10 22 171 7.4E-24 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS12625 c137bd4e8f64c2a5c08d7564a43b632a 731 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 66 731 2.8E-69 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS12625 c137bd4e8f64c2a5c08d7564a43b632a 731 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 165 1.2E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS00705 2d0b0887733b2e6be77bfe28d61ded24 156 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 85 132 3.7E-18 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CVS48_RS00705 2d0b0887733b2e6be77bfe28d61ded24 156 Pfam PF12728 Helix-turn-helix domain 85 133 3.7E-10 T 29-03-2018 CVS48_RS00705 2d0b0887733b2e6be77bfe28d61ded24 156 Gene3D G3DSA:1.10.10.10 84 143 3.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 425 444 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 SUPERFAMILY SSF52518 367 545 5.0E-61 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 172 1.0E-52 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 329 9.8E-25 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 535 3.5E-45 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 SUPERFAMILY SSF52518 9 180 1.63E-51 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 SUPERFAMILY SSF52467 158 357 3.27E-35 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 Gene3D G3DSA:3.40.50.970 345 547 1.4E-44 T 29-03-2018 CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 Gene3D G3DSA:3.40.50.1220 188 344 1.1E-30 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS13555 fa9addec9a8577d9c68b5595cdedc702 560 Gene3D G3DSA:3.40.50.970 1 187 2.3E-50 T 29-03-2018 CVS48_RS07245 682ce6d727fd47caa97db48ee4892327 179 PIRSF PIRSF039093 1 179 1.1E-85 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CVS48_RS07245 682ce6d727fd47caa97db48ee4892327 179 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 41.023 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CVS48_RS07245 682ce6d727fd47caa97db48ee4892327 179 Gene3D G3DSA:3.60.20.10 7 178 1.8E-29 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS07245 682ce6d727fd47caa97db48ee4892327 179 SUPERFAMILY SSF56235 3 177 2.24E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS07245 682ce6d727fd47caa97db48ee4892327 179 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 3.1E-84 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CVS48_RS07245 682ce6d727fd47caa97db48ee4892327 179 Pfam PF00227 Proteasome subunit 5 175 2.2E-21 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CVS48_RS24720 00d763e66ca0f522ac1fbbe65c87c622 443 SUPERFAMILY SSF103473 16 406 5.49E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS24720 00d763e66ca0f522ac1fbbe65c87c622 443 Gene3D G3DSA:1.20.1250.20 215 413 1.9E-11 T 29-03-2018 CVS48_RS24720 00d763e66ca0f522ac1fbbe65c87c622 443 Pfam PF07690 Major Facilitator Superfamily 17 347 5.3E-16 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS24720 00d763e66ca0f522ac1fbbe65c87c622 443 Gene3D G3DSA:1.20.1250.20 4 197 1.9E-11 T 29-03-2018 CVS48_RS16180 c0dbb9eddd17b84874349bc45b6754a8 162 SUPERFAMILY SSF54523 13 108 4.39E-10 T 29-03-2018 CVS48_RS16180 c0dbb9eddd17b84874349bc45b6754a8 162 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 10 159 9.7E-28 T 29-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 CVS48_RS16180 c0dbb9eddd17b84874349bc45b6754a8 162 PRINTS PR00885 Bacterial general secretion pathway protein H signature 8 22 5.8E-7 T 29-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 CVS48_RS16180 c0dbb9eddd17b84874349bc45b6754a8 162 PRINTS PR00885 Bacterial general secretion pathway protein H signature 23 37 5.8E-7 T 29-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 CVS48_RS16180 c0dbb9eddd17b84874349bc45b6754a8 162 Pfam PF12019 Type II transport protein GspH 47 152 6.0E-8 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 CVS48_RS16180 c0dbb9eddd17b84874349bc45b6754a8 162 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS16180 c0dbb9eddd17b84874349bc45b6754a8 162 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 32 1.5E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS16180 c0dbb9eddd17b84874349bc45b6754a8 162 Gene3D G3DSA:3.55.40.10 41 162 1.1E-15 T 29-03-2018 CVS48_RS16180 c0dbb9eddd17b84874349bc45b6754a8 162 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 32 1.6E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS13525 820090550fda3587f9632082de74994b 302 Gene3D G3DSA:3.40.50.300 120 300 3.6E-23 T 29-03-2018 CVS48_RS13525 820090550fda3587f9632082de74994b 302 SUPERFAMILY SSF47413 15 85 1.01E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS13525 820090550fda3587f9632082de74994b 302 Pfam PF01202 Shikimate kinase 137 286 7.3E-33 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CVS48_RS13525 820090550fda3587f9632082de74994b 302 Pfam PF01381 Helix-turn-helix 26 79 2.6E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS13525 820090550fda3587f9632082de74994b 302 Gene3D G3DSA:1.10.260.40 12 87 2.1E-14 T 29-03-2018 CVS48_RS13525 820090550fda3587f9632082de74994b 302 SMART SM00530 24 79 3.6E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS13525 820090550fda3587f9632082de74994b 302 SUPERFAMILY SSF52540 130 288 1.02E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13525 820090550fda3587f9632082de74994b 302 Hamap MF_00109 Shikimate kinase [aroK]. 128 295 20.341 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CVS48_RS13525 820090550fda3587f9632082de74994b 302 PRINTS PR01100 Shikimate kinase family signature 202 211 1.0E-11 T 29-03-2018 CVS48_RS13525 820090550fda3587f9632082de74994b 302 PRINTS PR01100 Shikimate kinase family signature 131 146 1.0E-11 T 29-03-2018 CVS48_RS13525 820090550fda3587f9632082de74994b 302 PRINTS PR01100 Shikimate kinase family signature 183 191 1.0E-11 T 29-03-2018 CVS48_RS13525 820090550fda3587f9632082de74994b 302 PRINTS PR01100 Shikimate kinase family signature 155 168 1.0E-11 T 29-03-2018 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 1.6E-249 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 136 348 3.9E-64 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 Gene3D G3DSA:1.10.1140.10 354 464 3.8E-44 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 SMART SM00382 148 325 0.0037 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 SUPERFAMILY SSF47917 351 466 6.54E-54 T 29-03-2018 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 56.435 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 Gene3D G3DSA:3.40.50.300 82 353 2.8E-90 T 29-03-2018 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 SUPERFAMILY SSF52540 83 353 1.34E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 SUPERFAMILY SSF50615 1 81 1.96E-24 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 Gene3D G3DSA:2.40.10.170 1 81 2.9E-28 T 29-03-2018 CVS48_RS04090 607141ac0fd25603ee3e43b1ed99448a 467 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 79 5.8E-19 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 1.4E-35 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 Gene3D G3DSA:3.30.70.1050 1 119 1.1E-27 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 265 418 2.8E-33 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 Hamap MF_00303 Trigger factor [tig]. 1 423 20.267 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 SUPERFAMILY SSF109998 250 435 2.09E-44 T 29-03-2018 IPR027304 Trigger factor/SurA domain CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 Gene3D G3DSA:3.10.50.40 159 228 3.4E-13 T 29-03-2018 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 Gene3D G3DSA:1.10.3120.10 229 394 1.1E-41 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 9.5E-13 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 SUPERFAMILY SSF54534 98 243 1.52E-30 T 29-03-2018 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 PIRSF PIRSF003095 1 436 4.8E-126 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 SUPERFAMILY SSF102735 1 130 1.05E-30 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CVS48_RS21975 9064d05e41fa4fc5d1a198c45b1116e5 436 TIGRFAM TIGR00115 tig: trigger factor 11 416 6.7E-130 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 Pfam PF02142 MGS-like domain 15 129 3.0E-28 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 PIRSF PIRSF000414 1 529 6.0E-211 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 459 8.9E-115 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 529 43.492 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 5 529 1.9E-219 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 SMART SM00851 15 130 5.8E-57 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 Gene3D G3DSA:3.40.140.20 376 519 2.2E-52 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 SUPERFAMILY SSF52335 3 198 1.02E-64 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 Gene3D G3DSA:3.40.140.20 237 375 1.2E-52 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 Gene3D G3DSA:3.40.50.1380 1 197 2.4E-71 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 SMART SM00798 135 461 3.9E-196 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS01415 af4998767dfe5c1e945633b39997aca8 529 SUPERFAMILY SSF53927 224 529 8.72E-127 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CVS48_RS11120 635e0cf0cada7884735284dd1a619f0c 267 Pfam PF00005 ABC transporter 20 175 3.9E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS11120 635e0cf0cada7884735284dd1a619f0c 267 SUPERFAMILY SSF52540 4 244 7.17E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS11120 635e0cf0cada7884735284dd1a619f0c 267 SMART SM00382 28 222 1.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS11120 635e0cf0cada7884735284dd1a619f0c 267 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 244 2.2E-8 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS11120 635e0cf0cada7884735284dd1a619f0c 267 Gene3D G3DSA:3.40.50.300 1 259 7.1E-52 T 29-03-2018 CVS48_RS13915 3b4975591d6613903a78e2d29d766811 315 SUPERFAMILY SSF51569 5 293 2.38E-74 T 29-03-2018 CVS48_RS13915 3b4975591d6613903a78e2d29d766811 315 Pfam PF00682 HMGL-like 7 277 2.8E-48 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CVS48_RS13915 3b4975591d6613903a78e2d29d766811 315 Gene3D G3DSA:3.20.20.70 3 298 1.6E-90 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS04415 c08454ec74e6893bd86f0793588a4264 99 SUPERFAMILY SSF54292 10 93 1.66E-16 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS04415 c08454ec74e6893bd86f0793588a4264 99 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 85 8.6E-9 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS04415 c08454ec74e6893bd86f0793588a4264 99 Gene3D G3DSA:3.10.20.30 2 96 6.7E-17 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS15500 c15ddec9a6d0f9e39155c9c391d74aa8 145 Pfam PF02082 Transcriptional regulator 1 83 2.4E-21 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CVS48_RS15500 c15ddec9a6d0f9e39155c9c391d74aa8 145 SUPERFAMILY SSF46785 2 133 4.91E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15500 c15ddec9a6d0f9e39155c9c391d74aa8 145 Gene3D G3DSA:1.10.10.10 1 143 8.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15500 c15ddec9a6d0f9e39155c9c391d74aa8 145 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 5.8E-28 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 Gene3D G3DSA:1.20.1580.10 88 397 5.7E-59 T 29-03-2018 CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 Gene3D G3DSA:3.40.50.300 519 858 5.8E-52 T 29-03-2018 CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 Pfam PF00005 ABC transporter 530 780 3.9E-7 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 Gene3D G3DSA:3.40.50.300 4 31 0.22 T 29-03-2018 CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 SUPERFAMILY SSF52540 599 833 1.33E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 SUPERFAMILY SSF52540 521 568 1.33E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 ProSitePatterns PS00211 ABC transporters family signature. 750 764 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 SUPERFAMILY SSF52540 2 84 3.06E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 SUPERFAMILY SSF52540 138 272 3.06E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 SUPERFAMILY SSF52540 340 479 3.06E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS11980 94654a77cadcdfff613bee8e35b7854c 863 Gene3D G3DSA:3.40.50.300 32 66 0.16 T 29-03-2018 CVS48_RS11040 10b47d6e5ecf5d292443bd3974aa0234 321 Gene3D G3DSA:3.30.1330.10 1 142 2.6E-37 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS11040 10b47d6e5ecf5d292443bd3974aa0234 321 Pfam PF02769 AIR synthase related protein, C-terminal domain 182 300 9.7E-8 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS11040 10b47d6e5ecf5d292443bd3974aa0234 321 Gene3D G3DSA:3.90.650.10 143 318 9.2E-39 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS11040 10b47d6e5ecf5d292443bd3974aa0234 321 SUPERFAMILY SSF56042 141 304 1.94E-31 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS11040 10b47d6e5ecf5d292443bd3974aa0234 321 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 2 315 27.185 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CVS48_RS11040 10b47d6e5ecf5d292443bd3974aa0234 321 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 318 9.5E-91 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CVS48_RS11040 10b47d6e5ecf5d292443bd3974aa0234 321 SUPERFAMILY SSF55326 4 136 1.05E-34 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS11040 10b47d6e5ecf5d292443bd3974aa0234 321 PIRSF PIRSF005303 2 318 4.8E-74 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CVS48_RS11040 10b47d6e5ecf5d292443bd3974aa0234 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 25 136 2.1E-25 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS16600 e31c955d8c6f6c141f13314c627f2751 237 Gene3D G3DSA:3.40.50.300 4 224 5.6E-52 T 29-03-2018 CVS48_RS16600 e31c955d8c6f6c141f13314c627f2751 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS16600 e31c955d8c6f6c141f13314c627f2751 237 SMART SM00382 32 215 2.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16600 e31c955d8c6f6c141f13314c627f2751 237 Pfam PF00005 ABC transporter 23 165 2.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS16600 e31c955d8c6f6c141f13314c627f2751 237 SUPERFAMILY SSF52540 6 222 8.85E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00780 7d36efc7a5e9e68e8d47e573315629e1 759 SUPERFAMILY SSF52540 571 736 1.51E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00780 7d36efc7a5e9e68e8d47e573315629e1 759 SUPERFAMILY SSF52540 351 393 1.51E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00780 7d36efc7a5e9e68e8d47e573315629e1 759 SMART SM00487 69 413 2.6E-10 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS00780 7d36efc7a5e9e68e8d47e573315629e1 759 Pfam PF00271 Helicase conserved C-terminal domain 585 695 2.5E-6 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS00780 7d36efc7a5e9e68e8d47e573315629e1 759 Gene3D G3DSA:3.40.50.300 572 732 4.2E-17 T 29-03-2018 CVS48_RS00780 7d36efc7a5e9e68e8d47e573315629e1 759 Gene3D G3DSA:3.40.50.10810 56 541 7.1E-26 T 29-03-2018 CVS48_RS00780 7d36efc7a5e9e68e8d47e573315629e1 759 SUPERFAMILY SSF52540 69 159 3.54E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00780 7d36efc7a5e9e68e8d47e573315629e1 759 SUPERFAMILY SSF52540 187 206 3.54E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00780 7d36efc7a5e9e68e8d47e573315629e1 759 SUPERFAMILY SSF52540 345 411 3.54E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 9.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 9.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 9.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 9.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 1.5E-5 T 29-03-2018 CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 Gene3D G3DSA:3.40.50.720 1 61 9.9E-13 T 29-03-2018 CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 Gene3D G3DSA:3.40.50.720 62 248 6.7E-51 T 29-03-2018 CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 SUPERFAMILY SSF51735 5 247 1.69E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS20490 870b024d6d39bd40589250da71d23c2f 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 1.1E-54 T 29-03-2018 CVS48_RS21430 88ccac96bb6b65503c11b7bf9b208dae 425 Gene3D G3DSA:3.30.70.150 1 135 6.2E-39 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CVS48_RS21430 88ccac96bb6b65503c11b7bf9b208dae 425 Gene3D G3DSA:3.20.20.110 137 424 1.0E-99 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CVS48_RS21430 88ccac96bb6b65503c11b7bf9b208dae 425 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 183 191 - T 29-03-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CVS48_RS21430 88ccac96bb6b65503c11b7bf9b208dae 425 SUPERFAMILY SSF54966 4 135 4.06E-35 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CVS48_RS21430 88ccac96bb6b65503c11b7bf9b208dae 425 SUPERFAMILY SSF51649 135 423 1.96E-90 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CVS48_RS21430 88ccac96bb6b65503c11b7bf9b208dae 425 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 141 421 3.2E-79 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CVS48_RS21430 88ccac96bb6b65503c11b7bf9b208dae 425 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 16 131 6.5E-6 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Gene3D G3DSA:3.90.199.10 286 375 4.3E-10 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 SUPERFAMILY SSF101904 544 863 2.75E-112 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 SMART SM00434 11 506 3.5E-289 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Gene3D G3DSA:3.90.199.10 34 285 1.7E-118 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Gene3D G3DSA:2.120.10.90 544 869 4.8E-132 T 29-03-2018 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 SUPERFAMILY SSF56719 30 524 9.94E-179 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 805 851 2.4E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 599 648 2.7E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 699 3.0E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 704 749 2.4E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 594 1.8E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 755 802 1.1E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Gene3D G3DSA:1.10.268.10 376 504 8.0E-47 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 2 853 24.128 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 852 0.0 T 29-03-2018 CVS48_RS27530 4839064a7e653c9707e5555a7ebdf292 894 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 513 9.0E-156 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS04120 0dacaf4cdb6afb959144d8b7f795239d 293 Pfam PF00119 ATP synthase A chain 43 286 1.0E-55 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04120 0dacaf4cdb6afb959144d8b7f795239d 293 ProSitePatterns PS00449 ATP synthase a subunit signature. 216 225 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04120 0dacaf4cdb6afb959144d8b7f795239d 293 Hamap MF_01393 ATP synthase subunit a [atpB]. 32 293 14.064 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04120 0dacaf4cdb6afb959144d8b7f795239d 293 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 33 288 1.6E-40 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04120 0dacaf4cdb6afb959144d8b7f795239d 293 SUPERFAMILY SSF81336 96 286 5.89E-37 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04120 0dacaf4cdb6afb959144d8b7f795239d 293 Gene3D G3DSA:1.20.120.220 93 293 4.4E-41 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 Pfam PF03466 LysR substrate binding domain 87 252 2.5E-21 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 Gene3D G3DSA:1.10.10.10 1 89 3.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 SUPERFAMILY SSF53850 86 295 6.52E-24 T 29-03-2018 CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.8E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 Gene3D G3DSA:3.40.190.10 169 268 3.1E-8 T 29-03-2018 CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 SUPERFAMILY SSF46785 1 109 1.14E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11530 d4e18211f832bf9686d0c14b63c263cc 308 Gene3D G3DSA:3.40.190.10 90 168 1.8E-11 T 29-03-2018 CVS48_RS21640 6aad516cb2d3c05b2f6f0ccad140ccc4 629 Pfam PF13476 AAA domain 21 261 1.0E-6 T 29-03-2018 CVS48_RS21640 6aad516cb2d3c05b2f6f0ccad140ccc4 629 Gene3D G3DSA:3.40.50.300 2 297 9.0E-9 T 29-03-2018 CVS48_RS21640 6aad516cb2d3c05b2f6f0ccad140ccc4 629 Gene3D G3DSA:1.20.120.330 354 466 0.033 T 29-03-2018 CVS48_RS21640 6aad516cb2d3c05b2f6f0ccad140ccc4 629 SUPERFAMILY SSF52540 212 306 4.14E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21640 6aad516cb2d3c05b2f6f0ccad140ccc4 629 SUPERFAMILY SSF52540 23 170 4.14E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03820 085001d742562069fef00edacd7ee954 212 Pfam PF03458 UPF0126 domain 13 85 2.4E-16 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CVS48_RS03820 085001d742562069fef00edacd7ee954 212 Pfam PF03458 UPF0126 domain 98 168 4.6E-20 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CVS48_RS28110 8667fc3c4e6371527b2a8463191e7833 278 SUPERFAMILY SSF161098 68 255 1.31E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28110 8667fc3c4e6371527b2a8463191e7833 278 Gene3D G3DSA:1.10.3720.10 10 263 2.6E-44 T 29-03-2018 CVS48_RS28110 8667fc3c4e6371527b2a8463191e7833 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 274 3.1E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS16415 ebbd7415e618044099893be300028b0e 570 Gene3D G3DSA:3.40.50.300 18 350 1.8E-24 T 29-03-2018 CVS48_RS16415 ebbd7415e618044099893be300028b0e 570 Pfam PF01926 50S ribosome-binding GTPase 55 178 1.4E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS16415 ebbd7415e618044099893be300028b0e 570 SUPERFAMILY SSF52540 45 185 1.18E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07405 05772afccd0066320a00a8948eb388d2 352 Gene3D G3DSA:3.40.50.2000 171 319 1.4E-31 T 29-03-2018 CVS48_RS07405 05772afccd0066320a00a8948eb388d2 352 Pfam PF00534 Glycosyl transferases group 1 179 290 1.6E-19 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS07405 05772afccd0066320a00a8948eb388d2 352 Gene3D G3DSA:3.40.50.2000 1 170 5.2E-10 T 29-03-2018 CVS48_RS07405 05772afccd0066320a00a8948eb388d2 352 SUPERFAMILY SSF53756 1 327 5.38E-63 T 29-03-2018 CVS48_RS07405 05772afccd0066320a00a8948eb388d2 352 Pfam PF13439 Glycosyltransferase Family 4 14 164 7.7E-18 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS13770 d3719b1a4dd81c84c4f7c181f1628458 120 SUPERFAMILY SSF52172 7 119 1.32E-26 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS13770 d3719b1a4dd81c84c4f7c181f1628458 120 Gene3D G3DSA:3.40.50.2300 1 120 1.4E-28 T 29-03-2018 CVS48_RS13770 d3719b1a4dd81c84c4f7c181f1628458 120 Pfam PF00072 Response regulator receiver domain 9 116 7.7E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS13770 d3719b1a4dd81c84c4f7c181f1628458 120 SMART SM00448 7 116 1.8E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 Gene3D G3DSA:1.10.10.10 1 81 1.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 Gene3D G3DSA:3.40.190.10 82 201 3.4E-14 T 29-03-2018 CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 SUPERFAMILY SSF46785 2 112 2.55E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 Gene3D G3DSA:3.40.190.10 202 290 5.0E-14 T 29-03-2018 CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 Pfam PF03466 LysR substrate binding domain 89 312 1.1E-27 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 SUPERFAMILY SSF53850 91 317 1.77E-26 T 29-03-2018 CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.1E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21890 4f910a8835c4d45ab45aa106bbed01d4 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 Gene3D G3DSA:3.20.20.100 3 271 7.8E-99 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 Pfam PF00248 Aldo/keto reductase family 18 262 3.2E-51 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 PRINTS PR00069 Aldo-keto reductase signature 37 61 2.6E-44 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 PRINTS PR00069 Aldo-keto reductase signature 93 111 2.6E-44 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 PRINTS PR00069 Aldo-keto reductase signature 159 188 2.6E-44 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 PRINTS PR00069 Aldo-keto reductase signature 125 142 2.6E-44 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 PRINTS PR00069 Aldo-keto reductase signature 196 220 2.6E-44 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 PIRSF PIRSF000097 1 270 3.4E-94 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS15335 f46e663864200a68fbcf91df1fe62781 275 SUPERFAMILY SSF51430 7 266 1.03E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS10600 0f317187024475080370bd4f6f04dd7b 491 PIRSF PIRSF012702 1 491 1.2E-165 T 29-03-2018 IPR009197 Microcystin LR degradation protein MlrC CVS48_RS10600 0f317187024475080370bd4f6f04dd7b 491 Pfam PF07364 Metallopeptidase family M81 2 289 7.4E-86 T 29-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CVS48_RS10600 0f317187024475080370bd4f6f04dd7b 491 Pfam PF07171 MlrC C-terminus 299 480 1.2E-50 T 29-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CVS48_RS13780 83042c9c164d34ad95417a248283710b 175 Pfam PF02627 Carboxymuconolactone decarboxylase family 39 121 4.9E-13 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS13780 83042c9c164d34ad95417a248283710b 175 Gene3D G3DSA:1.20.5.810 11 40 2.5E-4 T 29-03-2018 CVS48_RS13780 83042c9c164d34ad95417a248283710b 175 Gene3D G3DSA:1.20.1290.10 41 175 3.1E-43 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS13780 83042c9c164d34ad95417a248283710b 175 SUPERFAMILY SSF69118 1 171 1.73E-43 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS19655 db933f894ebdfbf55943e15c7ccf5cf6 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 417 1.3E-90 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS19655 db933f894ebdfbf55943e15c7ccf5cf6 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 423 5.3E-96 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS19655 db933f894ebdfbf55943e15c7ccf5cf6 427 PIRSF PIRSF006066 1 427 2.3E-93 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 Gene3D G3DSA:4.10.520.10 11 108 2.0E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 12 105 1.8E-43 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 SMART SM00411 13 102 7.0E-44 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 SUPERFAMILY SSF47729 13 102 1.31E-32 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 Pfam PF00216 Bacterial DNA-binding protein 13 101 2.4E-31 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 11 107 30.041 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 PRINTS PR01727 Prokaryotic integration host factor signature 86 100 5.5E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 PRINTS PR01727 Prokaryotic integration host factor signature 52 67 5.5E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 PRINTS PR01727 Prokaryotic integration host factor signature 70 83 5.5E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS15190 3ce3955649da792d60539e4087584834 113 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 58 77 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 Gene3D G3DSA:3.60.20.10 41 474 7.8E-162 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 Pfam PF00310 Glutamine amidotransferases class-II 41 464 1.5E-184 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 Gene3D G3DSA:3.20.20.70 817 1286 5.7E-167 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 SUPERFAMILY SSF56235 41 467 1.62E-153 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 Pfam PF01493 GXGXG motif 1311 1498 1.7E-78 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 SUPERFAMILY SSF69336 1280 1568 3.4E-90 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 Pfam PF01645 Conserved region in glutamate synthase 834 1233 1.7E-155 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 Pfam PF04898 Glutamate synthase central domain 494 773 1.3E-109 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 Gene3D G3DSA:3.20.20.70 475 816 6.7E-93 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 SUPERFAMILY SSF51395 973 1267 7.33E-262 T 29-03-2018 CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 SUPERFAMILY SSF51395 486 943 7.33E-262 T 29-03-2018 CVS48_RS05015 834923df62a111dd9b4dc76c056a1912 1579 Gene3D G3DSA:2.160.20.60 1287 1579 6.2E-110 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CVS48_RS24080 920f7d09f23cbecab80fdc3a6f5c5103 528 Pfam PF03471 Transporter associated domain 432 514 1.3E-22 T 29-03-2018 IPR005170 Transporter-associated domain CVS48_RS24080 920f7d09f23cbecab80fdc3a6f5c5103 528 Pfam PF03741 Integral membrane protein TerC family 14 204 1.8E-48 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CVS48_RS24080 920f7d09f23cbecab80fdc3a6f5c5103 528 Gene3D G3DSA:3.10.580.10 280 425 1.6E-20 T 29-03-2018 CVS48_RS24080 920f7d09f23cbecab80fdc3a6f5c5103 528 Gene3D G3DSA:3.30.465.10 426 515 9.9E-23 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS24080 920f7d09f23cbecab80fdc3a6f5c5103 528 SUPERFAMILY SSF54631 286 420 6.32E-21 T 29-03-2018 CVS48_RS24080 920f7d09f23cbecab80fdc3a6f5c5103 528 SMART SM01091 430 515 1.3E-24 T 29-03-2018 IPR005170 Transporter-associated domain CVS48_RS24080 920f7d09f23cbecab80fdc3a6f5c5103 528 SUPERFAMILY SSF56176 427 517 5.73E-21 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS14415 d271e5e615c358e50c87f6d6fdde225e 397 Gene3D G3DSA:2.130.10.10 304 392 9.8E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS14415 d271e5e615c358e50c87f6d6fdde225e 397 Gene3D G3DSA:2.130.10.10 41 303 1.1E-41 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS14415 d271e5e615c358e50c87f6d6fdde225e 397 SUPERFAMILY SSF50969 32 368 4.45E-74 T 29-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CVS48_RS14415 d271e5e615c358e50c87f6d6fdde225e 397 Pfam PF06433 Methylamine dehydrogenase heavy chain (MADH) 49 367 7.7E-47 T 29-03-2018 IPR009451 Amine dehydrogenase heavy chain GO:0030058|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 CVS48_RS00450 db61553fab50e37e7d235bb06e9d937f 553 PIRSF PIRSF003128 1 550 3.3E-161 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CVS48_RS00450 db61553fab50e37e7d235bb06e9d937f 553 Gene3D G3DSA:3.40.50.300 257 520 2.9E-21 T 29-03-2018 CVS48_RS00450 db61553fab50e37e7d235bb06e9d937f 553 SUPERFAMILY SSF52540 286 499 5.01E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00450 db61553fab50e37e7d235bb06e9d937f 553 SUPERFAMILY SSF52540 3 50 5.01E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00450 db61553fab50e37e7d235bb06e9d937f 553 Gene3D G3DSA:3.40.50.300 1 165 9.4E-23 T 29-03-2018 CVS48_RS00450 db61553fab50e37e7d235bb06e9d937f 553 SUPERFAMILY SSF52540 1 215 5.25E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00450 db61553fab50e37e7d235bb06e9d937f 553 Gene3D G3DSA:1.10.287.510 166 256 0.0011 T 29-03-2018 CVS48_RS00450 db61553fab50e37e7d235bb06e9d937f 553 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 546 1.7E-158 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CVS48_RS00450 db61553fab50e37e7d235bb06e9d937f 553 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 504 3.7E-20 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 Gene3D G3DSA:3.10.20.30 7 85 3.2E-10 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 PIRSF PIRSF037495 98 521 4.4E-103 T 29-03-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 SUPERFAMILY SSF51905 105 410 8.19E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 106 392 7.1E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 Gene3D G3DSA:3.50.50.60 105 242 6.2E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 264 4.2E-20 T 29-03-2018 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 126 4.2E-20 T 29-03-2018 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 365 387 4.2E-20 T 29-03-2018 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 202 220 4.2E-20 T 29-03-2018 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 SUPERFAMILY SSF54292 11 89 1.13E-14 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 Gene3D G3DSA:3.40.50.720 243 497 1.4E-20 T 29-03-2018 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 8 84 8.6E-17 T 29-03-2018 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 211 2.0E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 266 2.0E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 375 393 2.0E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS27755 d6c7b1069fbbb13bee1fec7d445e94a7 525 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 128 2.0E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS16990 4d7f9e7548b46447d25914386b290bd5 247 PRINTS PR01003 Flagellar assembly protein FliH signature 67 89 8.9E-18 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CVS48_RS16990 4d7f9e7548b46447d25914386b290bd5 247 PRINTS PR01003 Flagellar assembly protein FliH signature 198 214 8.9E-18 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CVS48_RS16990 4d7f9e7548b46447d25914386b290bd5 247 PRINTS PR01003 Flagellar assembly protein FliH signature 215 240 8.9E-18 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CVS48_RS16990 4d7f9e7548b46447d25914386b290bd5 247 PRINTS PR01003 Flagellar assembly protein FliH signature 129 146 8.9E-18 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CVS48_RS16990 4d7f9e7548b46447d25914386b290bd5 247 PRINTS PR01003 Flagellar assembly protein FliH signature 170 197 8.9E-18 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CVS48_RS16990 4d7f9e7548b46447d25914386b290bd5 247 PRINTS PR01003 Flagellar assembly protein FliH signature 90 108 8.9E-18 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CVS48_RS16990 4d7f9e7548b46447d25914386b290bd5 247 Pfam PF02108 Flagellar assembly protein FliH 107 233 1.5E-38 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CVS48_RS01725 aa6d7d125dffeb042342f978f5d90159 209 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 209 39.663 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CVS48_RS01725 aa6d7d125dffeb042342f978f5d90159 209 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 2 209 1.9E-87 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CVS48_RS01725 aa6d7d125dffeb042342f978f5d90159 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 32 118 4.1E-28 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CVS48_RS01725 aa6d7d125dffeb042342f978f5d90159 209 PIRSF PIRSF000190 1 209 7.8E-83 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CVS48_RS01725 aa6d7d125dffeb042342f978f5d90159 209 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 179 192 - T 29-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CVS48_RS01725 aa6d7d125dffeb042342f978f5d90159 209 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 169 209 1.2E-21 T 29-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CVS48_RS01725 aa6d7d125dffeb042342f978f5d90159 209 SUPERFAMILY SSF50475 6 209 3.74E-68 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS01725 aa6d7d125dffeb042342f978f5d90159 209 Gene3D G3DSA:2.30.110.10 8 209 5.1E-78 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS27785 d99643ab9aff1c7f58a284a45c445327 319 Pfam PF04773 FecR protein 113 205 1.9E-14 T 29-03-2018 IPR006860 FecR protein CVS48_RS27785 d99643ab9aff1c7f58a284a45c445327 319 PIRSF PIRSF018266 5 317 5.3E-74 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS27785 d99643ab9aff1c7f58a284a45c445327 319 Pfam PF16220 Domain of unknown function (DUF4880) 15 56 4.0E-12 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS03745 97271ba8a6f9e0598271250cb7a37d2a 258 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 45 60 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CVS48_RS03745 97271ba8a6f9e0598271250cb7a37d2a 258 Pfam PF01209 ubiE/COQ5 methyltransferase family 30 255 5.2E-82 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CVS48_RS03745 97271ba8a6f9e0598271250cb7a37d2a 258 Gene3D G3DSA:3.40.50.150 29 255 8.2E-43 T 29-03-2018 CVS48_RS03745 97271ba8a6f9e0598271250cb7a37d2a 258 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 165 179 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CVS48_RS03745 97271ba8a6f9e0598271250cb7a37d2a 258 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 34 254 3.1E-73 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CVS48_RS03745 97271ba8a6f9e0598271250cb7a37d2a 258 SUPERFAMILY SSF53335 17 248 6.88E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS03745 97271ba8a6f9e0598271250cb7a37d2a 258 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 25 256 35.361 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CVS48_RS10860 fefdaf98d704ca4217be5d0f50fa5b83 299 PIRSF PIRSF010376 2 282 2.0E-87 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CVS48_RS10860 fefdaf98d704ca4217be5d0f50fa5b83 299 SUPERFAMILY SSF54211 6 156 3.34E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS10860 fefdaf98d704ca4217be5d0f50fa5b83 299 Gene3D G3DSA:3.30.70.890 161 298 3.6E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CVS48_RS10860 fefdaf98d704ca4217be5d0f50fa5b83 299 Gene3D G3DSA:3.30.230.10 4 159 1.5E-44 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS10860 fefdaf98d704ca4217be5d0f50fa5b83 299 Pfam PF00288 GHMP kinases N terminal domain 89 143 3.1E-10 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CVS48_RS10860 fefdaf98d704ca4217be5d0f50fa5b83 299 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 5 257 3.2E-70 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CVS48_RS10860 fefdaf98d704ca4217be5d0f50fa5b83 299 SUPERFAMILY SSF55060 160 278 1.87E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CVS48_RS10860 fefdaf98d704ca4217be5d0f50fa5b83 299 Pfam PF08544 GHMP kinases C terminal 208 260 1.4E-5 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CVS48_RS10860 fefdaf98d704ca4217be5d0f50fa5b83 299 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 4 274 32.001 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 SUPERFAMILY SSF56235 2 238 3.6E-73 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 SUPERFAMILY SSF53697 248 610 1.11E-108 T 29-03-2018 CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 Gene3D G3DSA:3.40.50.10490 460 608 3.5E-49 T 29-03-2018 CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 Pfam PF13522 Glutamine amidotransferase domain 61 195 1.8E-22 T 29-03-2018 CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 1.6E-250 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 Pfam PF01380 SIS domain 464 590 4.3E-26 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 Pfam PF01380 SIS domain 292 417 9.6E-27 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 Gene3D G3DSA:3.40.50.10490 243 459 4.5E-60 T 29-03-2018 CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 Gene3D G3DSA:3.60.20.10 2 242 7.5E-67 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS04870 df1c4064a684cb6224d11778e3136e5a 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 39.22 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CVS48_RS11000 a16dfa17d0cfa23233c5a3343c62a4fc 294 Gene3D G3DSA:1.10.3720.10 16 261 8.4E-28 T 29-03-2018 CVS48_RS11000 a16dfa17d0cfa23233c5a3343c62a4fc 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 256 1.4E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS11000 a16dfa17d0cfa23233c5a3343c62a4fc 294 SUPERFAMILY SSF161098 64 252 9.68E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS11000 a16dfa17d0cfa23233c5a3343c62a4fc 294 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 19 258 1.7E-82 T 29-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CVS48_RS14440 536b23d9f96eedd4a98b30cd0c1e602c 317 SMART SM00342 228 313 2.6E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS14440 536b23d9f96eedd4a98b30cd0c1e602c 317 Gene3D G3DSA:1.10.10.60 265 317 1.3E-13 T 29-03-2018 CVS48_RS14440 536b23d9f96eedd4a98b30cd0c1e602c 317 Pfam PF12833 Helix-turn-helix domain 235 315 7.7E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS14440 536b23d9f96eedd4a98b30cd0c1e602c 317 Gene3D G3DSA:1.10.10.60 208 264 2.8E-7 T 29-03-2018 CVS48_RS14440 536b23d9f96eedd4a98b30cd0c1e602c 317 Pfam PF14525 AraC-binding-like domain 19 188 5.6E-25 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CVS48_RS14440 536b23d9f96eedd4a98b30cd0c1e602c 317 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 313 2.5E-8 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS14440 536b23d9f96eedd4a98b30cd0c1e602c 317 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 297 2.5E-8 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS14440 536b23d9f96eedd4a98b30cd0c1e602c 317 SUPERFAMILY SSF46689 264 315 2.33E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 Gene3D G3DSA:3.30.70.920 45 133 4.3E-17 T 29-03-2018 CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 Gene3D G3DSA:1.10.10.10 1 44 4.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 SUPERFAMILY SSF54909 63 139 2.82E-14 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.1E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.1E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.1E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 Pfam PF01037 Lrp/AsnC ligand binding domain 69 137 4.0E-12 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 SMART SM00344 1 107 5.4E-16 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 2.9E-11 T 29-03-2018 CVS48_RS04545 c9862a304051c35148ca679931204b5f 141 SUPERFAMILY SSF46785 1 57 6.83E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 Gene3D G3DSA:3.40.50.720 3 245 1.2E-58 T 29-03-2018 CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 SUPERFAMILY SSF51735 4 245 1.79E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 243 9.5E-50 T 29-03-2018 CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 6.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 6.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28880 b6d720df5680064e944418f76d33855c 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 6.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01620 2cb2825b412240fe8331afc4cf962e34 597 Pfam PF02653 Branched-chain amino acid transport system / permease component 26 306 8.6E-31 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS01620 2cb2825b412240fe8331afc4cf962e34 597 Gene3D G3DSA:3.40.50.300 346 594 1.7E-52 T 29-03-2018 CVS48_RS01620 2cb2825b412240fe8331afc4cf962e34 597 Pfam PF00005 ABC transporter 367 523 1.9E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS01620 2cb2825b412240fe8331afc4cf962e34 597 Gene3D G3DSA:1.10.3470.10 10 311 8.5E-35 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS01620 2cb2825b412240fe8331afc4cf962e34 597 SUPERFAMILY SSF52540 348 593 9.18E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01620 2cb2825b412240fe8331afc4cf962e34 597 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 572 594 1.5E-11 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS01620 2cb2825b412240fe8331afc4cf962e34 597 SMART SM00382 374 572 4.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS26165 9a6620cc26e89952d046839556abaca9 366 Gene3D G3DSA:3.40.50.2000 174 344 2.1E-48 T 29-03-2018 CVS48_RS26165 9a6620cc26e89952d046839556abaca9 366 Pfam PF13439 Glycosyltransferase Family 4 15 161 6.7E-14 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS26165 9a6620cc26e89952d046839556abaca9 366 Gene3D G3DSA:3.40.50.2000 2 173 1.3E-16 T 29-03-2018 CVS48_RS26165 9a6620cc26e89952d046839556abaca9 366 SUPERFAMILY SSF53756 8 357 5.11E-75 T 29-03-2018 CVS48_RS26165 9a6620cc26e89952d046839556abaca9 366 Pfam PF00534 Glycosyl transferases group 1 170 336 1.8E-33 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS08005 57f261b2088544f79e5e570489c9084b 85 Pfam PF00462 Glutaredoxin 4 64 8.5E-23 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CVS48_RS08005 57f261b2088544f79e5e570489c9084b 85 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 5.9E-36 T 29-03-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 CVS48_RS08005 57f261b2088544f79e5e570489c9084b 85 Gene3D G3DSA:3.40.30.10 1 85 6.0E-30 T 29-03-2018 CVS48_RS08005 57f261b2088544f79e5e570489c9084b 85 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 CVS48_RS08005 57f261b2088544f79e5e570489c9084b 85 PRINTS PR00160 Glutaredoxin signature 4 22 5.8E-20 T 29-03-2018 IPR014025 Glutaredoxin subgroup CVS48_RS08005 57f261b2088544f79e5e570489c9084b 85 PRINTS PR00160 Glutaredoxin signature 47 60 5.8E-20 T 29-03-2018 IPR014025 Glutaredoxin subgroup CVS48_RS08005 57f261b2088544f79e5e570489c9084b 85 PRINTS PR00160 Glutaredoxin signature 61 74 5.8E-20 T 29-03-2018 IPR014025 Glutaredoxin subgroup CVS48_RS08005 57f261b2088544f79e5e570489c9084b 85 SUPERFAMILY SSF52833 1 84 9.01E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS13995 bf9a9cef680c671bc1fe8fd8c67ca969 389 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS13995 bf9a9cef680c671bc1fe8fd8c67ca969 389 SUPERFAMILY SSF51735 163 352 3.69E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13995 bf9a9cef680c671bc1fe8fd8c67ca969 389 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 4.1E-12 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CVS48_RS13995 bf9a9cef680c671bc1fe8fd8c67ca969 389 Gene3D G3DSA:3.90.180.10 1 188 1.7E-52 T 29-03-2018 CVS48_RS13995 bf9a9cef680c671bc1fe8fd8c67ca969 389 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 149 1.1E-30 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS13995 bf9a9cef680c671bc1fe8fd8c67ca969 389 Gene3D G3DSA:3.40.50.720 189 333 2.5E-18 T 29-03-2018 CVS48_RS13995 bf9a9cef680c671bc1fe8fd8c67ca969 389 SUPERFAMILY SSF50129 1 201 7.0E-60 T 29-03-2018 IPR011032 GroES-like CVS48_RS13995 bf9a9cef680c671bc1fe8fd8c67ca969 389 Pfam PF00107 Zinc-binding dehydrogenase 196 263 8.3E-9 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS23425 b8e7f418115c67cb2943f4e4042a8f00 257 SUPERFAMILY SSF46785 11 85 6.71E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23425 b8e7f418115c67cb2943f4e4042a8f00 257 Pfam PF09339 IclR helix-turn-helix domain 14 64 1.3E-9 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS23425 b8e7f418115c67cb2943f4e4042a8f00 257 SUPERFAMILY SSF55781 77 245 4.9E-27 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS23425 b8e7f418115c67cb2943f4e4042a8f00 257 Gene3D G3DSA:3.30.450.40 77 253 3.5E-27 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS23425 b8e7f418115c67cb2943f4e4042a8f00 257 Gene3D G3DSA:1.10.10.10 9 72 1.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23425 b8e7f418115c67cb2943f4e4042a8f00 257 SMART SM00346 10 101 2.7E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS25080 508dcd85372fd4f85b2fd88382ed9f40 316 Gene3D G3DSA:3.30.43.10 1 51 1.0E-19 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS25080 508dcd85372fd4f85b2fd88382ed9f40 316 SMART SM01092 226 314 1.3E-16 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CVS48_RS25080 508dcd85372fd4f85b2fd88382ed9f40 316 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 300 1.7E-6 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CVS48_RS25080 508dcd85372fd4f85b2fd88382ed9f40 316 SUPERFAMILY SSF55447 224 315 4.71E-18 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CVS48_RS25080 508dcd85372fd4f85b2fd88382ed9f40 316 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 221 5.5E-51 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CVS48_RS25080 508dcd85372fd4f85b2fd88382ed9f40 316 SUPERFAMILY SSF56176 1 220 2.23E-59 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS25080 508dcd85372fd4f85b2fd88382ed9f40 316 Gene3D G3DSA:3.30.390.50 224 316 2.6E-13 T 29-03-2018 CVS48_RS25080 508dcd85372fd4f85b2fd88382ed9f40 316 Gene3D G3DSA:3.30.465.10 55 221 4.2E-32 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS06785 30eeeb66536b974bbe2f2c7e2e341331 394 Gene3D G3DSA:1.20.1250.20 7 204 1.3E-28 T 29-03-2018 CVS48_RS06785 30eeeb66536b974bbe2f2c7e2e341331 394 Pfam PF07690 Major Facilitator Superfamily 48 318 2.4E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS06785 30eeeb66536b974bbe2f2c7e2e341331 394 Gene3D G3DSA:1.20.1250.20 205 393 5.1E-20 T 29-03-2018 CVS48_RS06785 30eeeb66536b974bbe2f2c7e2e341331 394 SUPERFAMILY SSF103473 13 392 9.16E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 Gene3D G3DSA:3.40.50.300 14 229 3.3E-37 T 29-03-2018 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 PRINTS PR00315 GTP-binding elongation factor signature 18 31 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 PRINTS PR00315 GTP-binding elongation factor signature 155 164 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 PRINTS PR00315 GTP-binding elongation factor signature 78 86 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 PRINTS PR00315 GTP-binding elongation factor signature 98 108 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 PRINTS PR00315 GTP-binding elongation factor signature 114 125 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 Pfam PF00009 Elongation factor Tu GTP binding domain 17 207 2.6E-38 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 Gene3D G3DSA:2.40.30.10 326 431 4.7E-22 T 29-03-2018 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 71 86 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 17 431 3.9E-162 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 SUPERFAMILY SSF50447 236 323 1.77E-20 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 SUPERFAMILY SSF50465 327 431 3.12E-27 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 Gene3D G3DSA:2.40.30.10 232 324 3.5E-22 T 29-03-2018 CVS48_RS27370 f218aefaab43457ec5e720244e36ef16 432 SUPERFAMILY SSF52540 17 242 1.69E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13335 cf352b13395926b547a93ef3bfaedbd2 399 PIRSF PIRSF038971 2 377 4.2E-111 T 29-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS13335 cf352b13395926b547a93ef3bfaedbd2 399 Gene3D G3DSA:2.30.40.10 301 380 1.2E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS13335 cf352b13395926b547a93ef3bfaedbd2 399 Gene3D G3DSA:3.20.20.140 58 300 2.2E-15 T 29-03-2018 CVS48_RS13335 cf352b13395926b547a93ef3bfaedbd2 399 Gene3D G3DSA:2.30.40.10 1 57 5.1E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS13335 cf352b13395926b547a93ef3bfaedbd2 399 SUPERFAMILY SSF51556 54 179 8.04E-19 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS13335 cf352b13395926b547a93ef3bfaedbd2 399 SUPERFAMILY SSF51556 216 343 8.04E-19 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS13335 cf352b13395926b547a93ef3bfaedbd2 399 Pfam PF01979 Amidohydrolase family 51 358 1.4E-13 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS13335 cf352b13395926b547a93ef3bfaedbd2 399 SUPERFAMILY SSF51338 344 378 2.68E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS13335 cf352b13395926b547a93ef3bfaedbd2 399 SUPERFAMILY SSF51338 2 54 2.68E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 7.9E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 SUPERFAMILY SSF46785 1 111 2.14E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 Gene3D G3DSA:3.40.190.10 179 270 7.3E-7 T 29-03-2018 CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 Gene3D G3DSA:3.40.190.10 91 178 6.7E-16 T 29-03-2018 CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 Pfam PF03466 LysR substrate binding domain 87 293 6.0E-24 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 Gene3D G3DSA:1.10.10.10 1 90 9.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15900 8332ed6b6d5e6865abb289593efccede 310 SUPERFAMILY SSF53850 88 300 5.7E-27 T 29-03-2018 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 149 240 1.8E-38 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 SUPERFAMILY SSF51735 5 153 4.16E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 SUPERFAMILY SSF69055 303 395 2.75E-27 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 7 396 45.062 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 Gene3D G3DSA:1.10.1740.10 314 397 1.4E-25 T 29-03-2018 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 Pfam PF13288 DXP reductoisomerase C-terminal domain 272 391 8.4E-39 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 Gene3D G3DSA:3.40.50.720 4 153 6.6E-46 T 29-03-2018 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 392 2.5E-142 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 135 1.9E-39 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 PIRSF PIRSF006205 4 398 1.1E-143 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CVS48_RS17150 ce1c1ba8de8296fc046f2e522bdb9325 399 SUPERFAMILY SSF55347 129 275 1.31E-62 T 29-03-2018 CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 542 5.7E-27 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 Gene3D G3DSA:3.40.50.1220 189 348 7.0E-37 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 SUPERFAMILY SSF52518 364 565 1.39E-51 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 Gene3D G3DSA:3.40.50.970 349 552 1.3E-37 T 29-03-2018 CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 424 443 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 Gene3D G3DSA:3.40.50.970 2 188 1.4E-47 T 29-03-2018 CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 7.0E-49 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 SUPERFAMILY SSF52518 2 175 4.82E-47 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 327 4.8E-27 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS18405 46f7522705b4de0ac1dddab000425b2a 589 SUPERFAMILY SSF52467 191 353 2.53E-40 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS09205 9170e463f1708b75caeb36c6166de207 229 SUPERFAMILY SSF100950 2 220 1.12E-77 T 29-03-2018 CVS48_RS09205 9170e463f1708b75caeb36c6166de207 229 Pfam PF01144 Coenzyme A transferase 7 218 8.7E-71 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS09205 9170e463f1708b75caeb36c6166de207 229 Gene3D G3DSA:3.40.1080.10 2 229 4.7E-80 T 29-03-2018 CVS48_RS09205 9170e463f1708b75caeb36c6166de207 229 SMART SM00882 6 219 2.3E-84 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS09205 9170e463f1708b75caeb36c6166de207 229 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 220 1.0E-113 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CVS48_RS09205 9170e463f1708b75caeb36c6166de207 229 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 SUPERFAMILY SSF48008 84 220 1.15E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 SUPERFAMILY SSF46785 11 80 3.26E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 3.7E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 3.7E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 2.1E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 Gene3D G3DSA:1.20.120.530 73 231 1.4E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 SMART SM00895 86 213 4.8E-13 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 Pfam PF07729 FCD domain 87 212 2.9E-18 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 Gene3D G3DSA:1.10.10.10 2 72 2.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24175 7af5a620cca02ac68e48fa57925af403 235 SMART SM00345 18 76 4.0E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS04810 f09e17cc074ef758606b154af4a61b70 305 Gene3D G3DSA:1.10.3470.10 5 296 3.7E-46 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS04810 f09e17cc074ef758606b154af4a61b70 305 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 13 304 1.2E-119 T 29-03-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type CVS48_RS04810 f09e17cc074ef758606b154af4a61b70 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 291 6.1E-44 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS08795 1e4aa622edf4c82e91d323af0ba231c7 438 SUPERFAMILY SSF103473 12 433 9.29E-86 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS08795 1e4aa622edf4c82e91d323af0ba231c7 438 Gene3D G3DSA:1.20.1250.20 243 438 1.7E-24 T 29-03-2018 CVS48_RS08795 1e4aa622edf4c82e91d323af0ba231c7 438 Pfam PF07690 Major Facilitator Superfamily 33 397 7.8E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS08795 1e4aa622edf4c82e91d323af0ba231c7 438 Gene3D G3DSA:1.20.1250.20 17 228 4.8E-33 T 29-03-2018 CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 Gene3D G3DSA:1.10.10.10 3 54 6.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 8.4E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 SUPERFAMILY SSF54909 66 147 4.96E-21 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 SMART SM00344 3 112 5.4E-41 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 2.7E-24 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 Gene3D G3DSA:3.30.70.920 56 149 1.5E-25 T 29-03-2018 CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS05755 5da74a18c3069e10aaed44c2e814bc0e 156 SUPERFAMILY SSF46785 2 63 3.35E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14355 0eef5c7afbfe2028ac108e691d387413 505 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 503 1.3E-232 T 29-03-2018 IPR033186 Helicase HerA-like C-terminal CVS48_RS14355 0eef5c7afbfe2028ac108e691d387413 505 Gene3D G3DSA:3.40.50.300 4 342 1.0E-25 T 29-03-2018 CVS48_RS14355 0eef5c7afbfe2028ac108e691d387413 505 SUPERFAMILY SSF52540 15 380 1.49E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05690 3622640d4f073c96d89da0b3477e6a83 243 PIRSF PIRSF039085 1 242 2.9E-105 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS05690 3622640d4f073c96d89da0b3477e6a83 243 SUPERFAMILY SSF52540 3 237 6.98E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05690 3622640d4f073c96d89da0b3477e6a83 243 Pfam PF00005 ABC transporter 19 167 8.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05690 3622640d4f073c96d89da0b3477e6a83 243 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05690 3622640d4f073c96d89da0b3477e6a83 243 Gene3D G3DSA:3.40.50.300 1 242 1.8E-71 T 29-03-2018 CVS48_RS05690 3622640d4f073c96d89da0b3477e6a83 243 SMART SM00382 28 215 1.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08100 603d79ebd6dd4fd748f819f70ab53c2b 321 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CVS48_RS08100 603d79ebd6dd4fd748f819f70ab53c2b 321 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CVS48_RS08100 603d79ebd6dd4fd748f819f70ab53c2b 321 Pfam PF00348 Polyprenyl synthetase 32 274 7.2E-78 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CVS48_RS08100 603d79ebd6dd4fd748f819f70ab53c2b 321 SUPERFAMILY SSF48576 6 320 1.44E-97 T 29-03-2018 IPR008949 Isoprenoid synthase domain CVS48_RS08100 603d79ebd6dd4fd748f819f70ab53c2b 321 Gene3D G3DSA:1.10.600.10 3 321 5.0E-99 T 29-03-2018 IPR008949 Isoprenoid synthase domain CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 5.9E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 Gene3D G3DSA:3.40.190.10 89 179 2.3E-19 T 29-03-2018 CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 Pfam PF03466 LysR substrate binding domain 91 292 3.7E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 Gene3D G3DSA:3.40.190.10 180 266 4.6E-16 T 29-03-2018 CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 SUPERFAMILY SSF46785 1 112 4.14E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 SUPERFAMILY SSF53850 93 296 1.71E-34 T 29-03-2018 CVS48_RS17430 984d44d225bd46576873800d964dcb09 308 Gene3D G3DSA:1.10.10.10 2 83 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16270 e3c5ea06fc8edcbffdb9a128a93dcfce 178 SUPERFAMILY SSF52980 5 177 5.9E-74 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CVS48_RS16270 e3c5ea06fc8edcbffdb9a128a93dcfce 178 PIRSF PIRSF011484 1 178 1.2E-71 T 29-03-2018 IPR009822 YaeQ CVS48_RS16270 e3c5ea06fc8edcbffdb9a128a93dcfce 178 Gene3D G3DSA:3.10.640.10 2 177 6.0E-81 T 29-03-2018 CVS48_RS16270 e3c5ea06fc8edcbffdb9a128a93dcfce 178 Pfam PF07152 YaeQ protein 1 173 2.7E-78 T 29-03-2018 IPR009822 YaeQ CVS48_RS16270 e3c5ea06fc8edcbffdb9a128a93dcfce 178 SMART SM01322 1 176 7.3E-121 T 29-03-2018 IPR009822 YaeQ CVS48_RS16785 a44868da4a54b27cf91f453b352e61c6 126 Pfam PF00072 Response regulator receiver domain 5 115 3.9E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS16785 a44868da4a54b27cf91f453b352e61c6 126 Gene3D G3DSA:3.40.50.2300 2 125 4.1E-36 T 29-03-2018 CVS48_RS16785 a44868da4a54b27cf91f453b352e61c6 126 SMART SM00448 3 116 5.2E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS16785 a44868da4a54b27cf91f453b352e61c6 126 SUPERFAMILY SSF52172 4 121 9.96E-36 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS08245 e201f295946d2a9ed2887d48cb9ba2e1 239 SMART SM00862 149 224 1.6E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS08245 e201f295946d2a9ed2887d48cb9ba2e1 239 Gene3D G3DSA:3.40.50.2300 1 122 4.9E-32 T 29-03-2018 CVS48_RS08245 e201f295946d2a9ed2887d48cb9ba2e1 239 Gene3D G3DSA:1.10.10.10 123 230 2.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08245 e201f295946d2a9ed2887d48cb9ba2e1 239 SUPERFAMILY SSF52172 1 117 1.99E-37 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS08245 e201f295946d2a9ed2887d48cb9ba2e1 239 SMART SM00448 1 111 1.0E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS08245 e201f295946d2a9ed2887d48cb9ba2e1 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 223 8.9E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS08245 e201f295946d2a9ed2887d48cb9ba2e1 239 Pfam PF00072 Response regulator receiver domain 3 111 2.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS08245 e201f295946d2a9ed2887d48cb9ba2e1 239 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 223 3.7E-86 T 29-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 CVS48_RS08245 e201f295946d2a9ed2887d48cb9ba2e1 239 SUPERFAMILY SSF46894 126 225 1.79E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1165 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 SUPERFAMILY SSF75553 519 673 4.05E-9 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 Gene3D G3DSA:3.40.50.300 2 232 7.8E-36 T 29-03-2018 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1158 7.6E-64 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 SUPERFAMILY SSF52540 2 210 1.24E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 SUPERFAMILY SSF52540 967 1167 1.24E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 Gene3D G3DSA:3.40.50.300 783 1170 7.7E-23 T 29-03-2018 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 Gene3D G3DSA:1.20.120.330 653 782 3.1E-7 T 29-03-2018 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 Gene3D G3DSA:1.10.287.620 233 390 4.2E-10 T 29-03-2018 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 Pfam PF06470 SMC proteins Flexible Hinge Domain 523 624 5.2E-5 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 SMART SM00968 518 625 1.8E-8 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1167 22.271 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 Gene3D G3DSA:1.20.5.340 391 529 0.035 T 29-03-2018 CVS48_RS28565 a23420a8860f74a31f7f8eb41a2c087c 1177 PIRSF PIRSF005719 1 1173 4.5E-249 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein CVS48_RS05220 7f79068e760637ae389515b9f2229f90 665 Gene3D G3DSA:2.20.150.10 27 47 9.2E-5 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CVS48_RS05220 7f79068e760637ae389515b9f2229f90 665 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 12 336 4.8E-117 T 29-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 CVS48_RS05220 7f79068e760637ae389515b9f2229f90 665 Pfam PF09863 Uncharacterized protein conserved in bacteria (DUF2090) 332 641 1.9E-125 T 29-03-2018 IPR018659 Protein of unknown function DUF2090 CVS48_RS05220 7f79068e760637ae389515b9f2229f90 665 Pfam PF00294 pfkB family carbohydrate kinase 14 329 5.0E-47 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CVS48_RS05220 7f79068e760637ae389515b9f2229f90 665 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 281 294 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CVS48_RS05220 7f79068e760637ae389515b9f2229f90 665 Gene3D G3DSA:3.40.1190.20 48 346 3.6E-55 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS05220 7f79068e760637ae389515b9f2229f90 665 Gene3D G3DSA:3.20.20.70 351 655 1.3E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS05220 7f79068e760637ae389515b9f2229f90 665 SUPERFAMILY SSF53613 12 334 3.59E-67 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 Gene3D G3DSA:3.40.190.10 107 199 1.5E-9 T 29-03-2018 CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 77 4.1E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 Gene3D G3DSA:3.40.190.10 200 288 1.7E-11 T 29-03-2018 CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 55 2.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 2.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 55 66 2.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 Pfam PF03466 LysR substrate binding domain 104 312 1.4E-20 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 SUPERFAMILY SSF53850 107 316 1.52E-21 T 29-03-2018 CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 Gene3D G3DSA:1.10.10.10 12 99 2.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12385 c5f9dc41fdd9b99e273994717593d27a 322 SUPERFAMILY SSF46785 16 126 3.41E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10970 8a291570f5f55b0a71604b36611ea69a 188 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 123 129 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CVS48_RS10970 8a291570f5f55b0a71604b36611ea69a 188 Gene3D G3DSA:3.40.50.150 1 188 1.5E-31 T 29-03-2018 CVS48_RS10970 8a291570f5f55b0a71604b36611ea69a 188 SUPERFAMILY SSF53335 5 180 8.65E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS10970 8a291570f5f55b0a71604b36611ea69a 188 Pfam PF03602 Conserved hypothetical protein 95 6 181 1.3E-45 T 29-03-2018 CVS48_RS10970 8a291570f5f55b0a71604b36611ea69a 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 4 182 1.6E-38 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CVS48_RS10970 8a291570f5f55b0a71604b36611ea69a 188 PIRSF PIRSF004553 5 185 3.7E-39 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CVS48_RS18905 eda585b484031ec52c04970f824985b4 398 Pfam PF07690 Major Facilitator Superfamily 20 359 1.5E-35 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS18905 eda585b484031ec52c04970f824985b4 398 Gene3D G3DSA:1.20.1250.20 205 390 8.8E-8 T 29-03-2018 CVS48_RS18905 eda585b484031ec52c04970f824985b4 398 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 14 377 5.4E-67 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CVS48_RS18905 eda585b484031ec52c04970f824985b4 398 SUPERFAMILY SSF103473 5 386 1.26E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS18905 eda585b484031ec52c04970f824985b4 398 Gene3D G3DSA:1.20.1250.20 8 197 3.1E-23 T 29-03-2018 CVS48_RS18905 eda585b484031ec52c04970f824985b4 398 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 84 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS12825 e5dbe4bcebe0002b14046a833c1cd332 529 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 433 517 2.8E-29 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS12825 e5dbe4bcebe0002b14046a833c1cd332 529 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 152 321 2.5E-45 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS12825 e5dbe4bcebe0002b14046a833c1cd332 529 SUPERFAMILY SSF142019 102 342 1.26E-86 T 29-03-2018 CVS48_RS12825 e5dbe4bcebe0002b14046a833c1cd332 529 SUPERFAMILY SSF140490 428 517 1.57E-27 T 29-03-2018 CVS48_RS12825 e5dbe4bcebe0002b14046a833c1cd332 529 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 444 455 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS12825 e5dbe4bcebe0002b14046a833c1cd332 529 SUPERFAMILY SSF142984 345 426 5.62E-19 T 29-03-2018 CVS48_RS12825 e5dbe4bcebe0002b14046a833c1cd332 529 SUPERFAMILY SSF52833 5 86 1.14E-6 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS12825 e5dbe4bcebe0002b14046a833c1cd332 529 SMART SM00928 431 476 5.4E-17 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS12825 e5dbe4bcebe0002b14046a833c1cd332 529 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 269 284 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 Pfam PF00696 Amino acid kinase family 16 244 4.7E-41 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 Gene3D G3DSA:2.30.130.10 286 377 7.9E-30 T 29-03-2018 IPR002478 PUA domain GO:0003723 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 SUPERFAMILY SSF88697 286 377 4.2E-25 T 29-03-2018 IPR015947 PUA-like domain CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 4.4E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 4.4E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 PRINTS PR00474 Glutamate 5-kinase family signature 52 66 4.4E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 PRINTS PR00474 Glutamate 5-kinase family signature 219 239 4.4E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 PRINTS PR00474 Glutamate 5-kinase family signature 86 114 4.4E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 Hamap MF_00456 Glutamate 5-kinase [proB]. 15 276 35.524 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 ProSitePatterns PS00902 Glutamate 5-kinase signature. 217 234 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 PIRSF PIRSF000729 10 378 2.4E-126 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 Pfam PF01472 PUA domain 287 361 4.2E-23 T 29-03-2018 IPR002478 PUA domain GO:0003723 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 Gene3D G3DSA:3.40.1160.10 5 267 3.7E-61 T 29-03-2018 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 SMART SM00359 287 370 4.3E-17 T 29-03-2018 IPR002478 PUA domain GO:0003723 CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 SUPERFAMILY SSF53633 15 264 1.83E-67 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS08070 fdd86dd25a61cb28c3d72485c21d165a 378 TIGRFAM TIGR01027 proB: glutamate 5-kinase 15 376 6.3E-127 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CVS48_RS14985 a4a83acf78e73455a7d22b0df0036565 269 Gene3D G3DSA:3.30.70.580 1 107 9.5E-34 T 29-03-2018 CVS48_RS14985 a4a83acf78e73455a7d22b0df0036565 269 Gene3D G3DSA:3.30.70.660 108 245 5.3E-39 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS14985 a4a83acf78e73455a7d22b0df0036565 269 Pfam PF01416 tRNA pseudouridine synthase 10 105 6.9E-7 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS14985 a4a83acf78e73455a7d22b0df0036565 269 Pfam PF01416 tRNA pseudouridine synthase 145 247 2.4E-31 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS14985 a4a83acf78e73455a7d22b0df0036565 269 PIRSF PIRSF001430 1 260 3.2E-77 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS14985 a4a83acf78e73455a7d22b0df0036565 269 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 241 5.9E-67 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS14985 a4a83acf78e73455a7d22b0df0036565 269 SUPERFAMILY SSF55120 1 251 1.19E-87 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS14985 a4a83acf78e73455a7d22b0df0036565 269 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 246 33.767 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS17615 e2a7f75f208f80d4521e164804c69d98 473 Pfam PF00155 Aminotransferase class I and II 147 458 1.3E-33 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS17615 e2a7f75f208f80d4521e164804c69d98 473 SUPERFAMILY SSF53383 110 466 2.3E-69 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS17615 e2a7f75f208f80d4521e164804c69d98 473 SMART SM00345 20 79 3.9E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS17615 e2a7f75f208f80d4521e164804c69d98 473 Gene3D G3DSA:3.40.640.10 132 378 5.4E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS17615 e2a7f75f208f80d4521e164804c69d98 473 Gene3D G3DSA:3.90.1150.10 379 471 9.7E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS17615 e2a7f75f208f80d4521e164804c69d98 473 SUPERFAMILY SSF46785 11 90 3.09E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17615 e2a7f75f208f80d4521e164804c69d98 473 Gene3D G3DSA:1.10.10.10 1 80 2.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17615 e2a7f75f208f80d4521e164804c69d98 473 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 1.0E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS20755 df6c7973db081c9b0144e786b9e89f66 81 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 36 3.8E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CVS48_RS20755 df6c7973db081c9b0144e786b9e89f66 81 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 35 1.8E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CVS48_RS20755 df6c7973db081c9b0144e786b9e89f66 81 SUPERFAMILY SSF89447 2 36 5.76E-10 T 29-03-2018 CVS48_RS20755 df6c7973db081c9b0144e786b9e89f66 81 Gene3D G3DSA:2.10.260.10 3 46 3.1E-12 T 29-03-2018 CVS48_RS20755 df6c7973db081c9b0144e786b9e89f66 81 SMART SM00966 4 51 7.2E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 SUPERFAMILY SSF47170 32 188 1.16E-16 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 Gene3D G3DSA:1.10.287.1060 255 342 0.0017 T 29-03-2018 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 Gene3D G3DSA:1.10.287.950 343 535 2.7E-51 T 29-03-2018 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 Pfam PF00672 HAMP domain 231 279 6.5E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 SMART SM00283 284 531 2.3E-98 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 Gene3D G3DSA:1.20.120.30 25 205 4.1E-25 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 459 488 1.1E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 1.1E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 305 334 1.1E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 411 440 1.1E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 382 409 1.1E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 SMART SM00304 231 283 2.0E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 SUPERFAMILY SSF58104 251 536 1.57E-77 T 29-03-2018 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 343 499 2.8E-56 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS16800 ddc46dbba560c5fbdebe9042a74a9323 567 Pfam PF02203 Tar ligand binding domain homologue 4 176 3.1E-21 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS09510 2f570afd2c4f91ceadddbcc8561bd306 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 5.6E-6 T 29-03-2018 CVS48_RS09510 2f570afd2c4f91ceadddbcc8561bd306 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 5.6E-6 T 29-03-2018 CVS48_RS09510 2f570afd2c4f91ceadddbcc8561bd306 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 5.6E-6 T 29-03-2018 CVS48_RS09510 2f570afd2c4f91ceadddbcc8561bd306 482 SUPERFAMILY SSF103473 265 480 3.49E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS09510 2f570afd2c4f91ceadddbcc8561bd306 482 SUPERFAMILY SSF103473 25 216 3.49E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS09510 2f570afd2c4f91ceadddbcc8561bd306 482 Pfam PF07690 Major Facilitator Superfamily 29 428 1.9E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS09510 2f570afd2c4f91ceadddbcc8561bd306 482 Gene3D G3DSA:1.20.1250.20 22 207 1.2E-25 T 29-03-2018 CVS48_RS09510 2f570afd2c4f91ceadddbcc8561bd306 482 Gene3D G3DSA:1.20.1250.20 269 482 1.5E-19 T 29-03-2018 CVS48_RS09785 6e3fca626c4eb2e41777fcb40679b5dd 271 Gene3D G3DSA:3.30.450.40 90 271 3.3E-31 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09785 6e3fca626c4eb2e41777fcb40679b5dd 271 SUPERFAMILY SSF46785 26 97 1.61E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09785 6e3fca626c4eb2e41777fcb40679b5dd 271 Gene3D G3DSA:1.10.10.10 8 85 1.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09785 6e3fca626c4eb2e41777fcb40679b5dd 271 Pfam PF09339 IclR helix-turn-helix domain 27 76 5.0E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS09785 6e3fca626c4eb2e41777fcb40679b5dd 271 SUPERFAMILY SSF55781 82 269 4.64E-31 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09785 6e3fca626c4eb2e41777fcb40679b5dd 271 SMART SM00346 24 114 1.2E-17 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS07645 88a95fd04882700894ae99d7d3d984fa 642 SUPERFAMILY SSF56601 252 612 3.19E-99 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS07645 88a95fd04882700894ae99d7d3d984fa 642 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 237 2.2E-40 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CVS48_RS07645 88a95fd04882700894ae99d7d3d984fa 642 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 607 6.3E-63 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CVS48_RS07645 88a95fd04882700894ae99d7d3d984fa 642 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 18 612 4.6E-222 T 29-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 CVS48_RS07645 88a95fd04882700894ae99d7d3d984fa 642 Gene3D G3DSA:3.40.710.10 248 617 5.4E-94 T 29-03-2018 CVS48_RS07645 88a95fd04882700894ae99d7d3d984fa 642 Gene3D G3DSA:3.90.1310.10 31 247 3.3E-48 T 29-03-2018 CVS48_RS07645 88a95fd04882700894ae99d7d3d984fa 642 SUPERFAMILY SSF56519 54 251 1.96E-46 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CVS48_RS05890 35bbc4c3bfba6a974a685e0f2e2924c4 687 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 181 3.8E-61 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CVS48_RS05890 35bbc4c3bfba6a974a685e0f2e2924c4 687 Gene3D G3DSA:3.40.50.2300 367 526 0.37 T 29-03-2018 CVS48_RS05890 35bbc4c3bfba6a974a685e0f2e2924c4 687 Gene3D G3DSA:3.30.420.40 279 323 0.0012 T 29-03-2018 CVS48_RS05890 35bbc4c3bfba6a974a685e0f2e2924c4 687 Pfam PF01968 Hydantoinase/oxoprolinase 202 488 9.1E-91 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CVS48_RS05890 35bbc4c3bfba6a974a685e0f2e2924c4 687 SUPERFAMILY SSF53067 260 344 1.65E-12 T 29-03-2018 CVS48_RS05890 35bbc4c3bfba6a974a685e0f2e2924c4 687 SUPERFAMILY SSF53067 1 78 1.65E-12 T 29-03-2018 CVS48_RS05890 35bbc4c3bfba6a974a685e0f2e2924c4 687 SUPERFAMILY SSF53067 383 481 1.65E-12 T 29-03-2018 CVS48_RS05890 35bbc4c3bfba6a974a685e0f2e2924c4 687 Gene3D G3DSA:3.30.420.40 1 106 9.9E-12 T 29-03-2018 CVS48_RS08085 2415be8218ac25337569520c79176c97 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS08085 2415be8218ac25337569520c79176c97 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.329 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08085 2415be8218ac25337569520c79176c97 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 2.0E-40 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08085 2415be8218ac25337569520c79176c97 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 5.8E-37 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08085 2415be8218ac25337569520c79176c97 103 SUPERFAMILY SSF141091 1 101 3.27E-38 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS17890 d62ec9ec8b4f5a5b647886bae66b4075 416 Gene3D G3DSA:3.90.1150.10 280 407 5.5E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS17890 d62ec9ec8b4f5a5b647886bae66b4075 416 SUPERFAMILY SSF53383 12 403 1.86E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS17890 d62ec9ec8b4f5a5b647886bae66b4075 416 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CVS48_RS17890 d62ec9ec8b4f5a5b647886bae66b4075 416 Pfam PF00155 Aminotransferase class I and II 40 399 3.0E-68 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS17890 d62ec9ec8b4f5a5b647886bae66b4075 416 Gene3D G3DSA:3.40.640.10 60 279 1.7E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS23980 bb60a43a943b391dc82c0e48a660fee9 555 Gene3D G3DSA:3.50.50.60 7 209 5.6E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23980 bb60a43a943b391dc82c0e48a660fee9 555 Pfam PF13454 FAD-NAD(P)-binding 16 179 2.8E-29 T 29-03-2018 CVS48_RS23980 bb60a43a943b391dc82c0e48a660fee9 555 SUPERFAMILY SSF51905 12 254 4.32E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23980 bb60a43a943b391dc82c0e48a660fee9 555 Gene3D G3DSA:3.50.50.60 210 531 2.2E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS17705 cee7a4a3ff82453ec38c406378577958 441 Gene3D G3DSA:1.20.1250.20 243 440 2.9E-14 T 29-03-2018 CVS48_RS17705 cee7a4a3ff82453ec38c406378577958 441 Gene3D G3DSA:1.20.1250.20 12 227 7.0E-21 T 29-03-2018 CVS48_RS17705 cee7a4a3ff82453ec38c406378577958 441 Pfam PF00083 Sugar (and other) transporter 16 228 3.6E-22 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS17705 cee7a4a3ff82453ec38c406378577958 441 SUPERFAMILY SSF103473 7 432 1.15E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 Pfam PF02203 Tar ligand binding domain homologue 5 170 4.5E-15 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 329 485 2.4E-49 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 SUPERFAMILY SSF47170 32 176 1.96E-8 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 SMART SM00283 270 517 1.2E-87 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 Gene3D G3DSA:1.10.287.950 21 323 1.6E-21 T 29-03-2018 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 Gene3D G3DSA:1.10.287.950 324 521 1.9E-46 T 29-03-2018 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 SMART SM00304 217 269 1.4E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 397 426 1.1E-51 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 291 320 1.1E-51 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 445 474 1.1E-51 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 368 395 1.1E-51 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 56 71 1.1E-51 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS04445 474aae1ba8eedddc7d666aa4854bfdf3 532 SUPERFAMILY SSF58104 237 518 6.41E-71 T 29-03-2018 CVS48_RS27195 92aed63a61ee5e524b6e68adb358686e 343 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 19 197 1.0E-39 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CVS48_RS27195 92aed63a61ee5e524b6e68adb358686e 343 SMART SM00833 244 338 1.9E-12 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS27195 92aed63a61ee5e524b6e68adb358686e 343 SUPERFAMILY SSF90002 244 337 2.62E-14 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS27195 92aed63a61ee5e524b6e68adb358686e 343 Gene3D G3DSA:3.30.1220.10 232 337 7.5E-9 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS27195 92aed63a61ee5e524b6e68adb358686e 343 Gene3D G3DSA:3.40.50.300 14 211 1.5E-31 T 29-03-2018 CVS48_RS27195 92aed63a61ee5e524b6e68adb358686e 343 SUPERFAMILY SSF52540 15 193 7.8E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27195 92aed63a61ee5e524b6e68adb358686e 343 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 244 337 9.6E-12 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 31 494 34.147 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 Pfam PF00342 Phosphoglucose isomerase 51 507 1.0E-140 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 PRINTS PR00662 Glucose-6-phosphate isomerase signature 453 467 8.2E-48 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 PRINTS PR00662 Glucose-6-phosphate isomerase signature 435 453 8.2E-48 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 PRINTS PR00662 Glucose-6-phosphate isomerase signature 308 329 8.2E-48 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 PRINTS PR00662 Glucose-6-phosphate isomerase signature 122 141 8.2E-48 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 PRINTS PR00662 Glucose-6-phosphate isomerase signature 467 480 8.2E-48 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 PRINTS PR00662 Glucose-6-phosphate isomerase signature 231 249 8.2E-48 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 467 484 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 Gene3D G3DSA:3.40.50.10490 229 481 2.0E-101 T 29-03-2018 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 Gene3D G3DSA:3.40.50.10490 115 228 1.5E-32 T 29-03-2018 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 Gene3D G3DSA:1.10.1390.10 482 517 5.6E-15 T 29-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 SUPERFAMILY SSF53697 29 513 3.34E-155 T 29-03-2018 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 235 248 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS10720 3d8a9bffdb55bfe81557a452f2471e97 517 Gene3D G3DSA:3.40.50.10490 10 114 2.4E-11 T 29-03-2018 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 121 2.5E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 PIRSF PIRSF016578 235 378 0.0064 T 29-03-2018 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 PIRSF PIRSF016578 1 229 5.1E-9 T 29-03-2018 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 Gene3D G3DSA:2.40.110.10 124 220 1.9E-37 T 29-03-2018 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 Gene3D G3DSA:1.10.540.10 2 123 1.7E-35 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 SUPERFAMILY SSF56645 7 242 5.89E-81 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 SUPERFAMILY SSF47203 232 379 4.35E-41 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 Gene3D G3DSA:1.20.140.10 221 379 3.8E-49 T 29-03-2018 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 2.0E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS11225 6c3ba1fc5affa3ca3a6c943ea8888af4 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 378 2.3E-39 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 Gene3D G3DSA:3.40.710.10 34 328 3.1E-65 T 29-03-2018 CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 69 294 1.7E-81 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 101 112 2.9E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 181 194 2.9E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 154 171 2.9E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 314 404 5.7E-20 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 Gene3D G3DSA:2.60.410.10 329 404 1.1E-18 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 SMART SM00936 314 404 1.3E-29 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 SUPERFAMILY SSF56601 17 44 1.05E-86 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 SUPERFAMILY SSF56601 73 314 1.05E-86 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS07195 20ed71af96fd30f1f76d8513ece9d444 420 SUPERFAMILY SSF69189 314 406 3.14E-22 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS24150 c1f2e41eda2b3266f2595e6bf0de92bb 335 Gene3D G3DSA:3.40.190.10 148 334 2.1E-21 T 29-03-2018 CVS48_RS24150 c1f2e41eda2b3266f2595e6bf0de92bb 335 Gene3D G3DSA:3.40.190.10 36 147 5.8E-14 T 29-03-2018 CVS48_RS24150 c1f2e41eda2b3266f2595e6bf0de92bb 335 SUPERFAMILY SSF53850 40 273 4.45E-36 T 29-03-2018 CVS48_RS24150 c1f2e41eda2b3266f2595e6bf0de92bb 335 Pfam PF09084 NMT1/THI5 like 53 272 1.2E-22 T 29-03-2018 IPR015168 SsuA/THI5-like CVS48_RS06830 c91f4e809a8afd38a5393c04898ca01e 325 SUPERFAMILY SSF46689 280 325 3.58E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS06830 c91f4e809a8afd38a5393c04898ca01e 325 Gene3D G3DSA:1.10.10.60 282 325 1.7E-11 T 29-03-2018 CVS48_RS06830 c91f4e809a8afd38a5393c04898ca01e 325 SUPERFAMILY SSF46689 227 277 5.11E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS06830 c91f4e809a8afd38a5393c04898ca01e 325 SMART SM00342 244 325 8.2E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS06830 c91f4e809a8afd38a5393c04898ca01e 325 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 310 325 6.0E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS06830 c91f4e809a8afd38a5393c04898ca01e 325 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 295 310 6.0E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS06830 c91f4e809a8afd38a5393c04898ca01e 325 Pfam PF12833 Helix-turn-helix domain 250 325 3.9E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS06830 c91f4e809a8afd38a5393c04898ca01e 325 Gene3D G3DSA:1.10.10.60 223 281 3.1E-10 T 29-03-2018 CVS48_RS11795 2ef6ef95f39ca83242620ede697227c2 402 TIGRFAM TIGR00843 benE: benzoate transporter 15 387 7.9E-113 T 29-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 CVS48_RS11795 2ef6ef95f39ca83242620ede697227c2 402 Pfam PF03594 Benzoate membrane transport protein 15 386 4.8E-136 T 29-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 CVS48_RS07615 22814c76f0031d44cf739f1abc68f465 485 SUPERFAMILY SSF55931 4 300 3.14E-118 T 29-03-2018 CVS48_RS07615 22814c76f0031d44cf739f1abc68f465 485 SUPERFAMILY SSF89095 301 407 7.06E-31 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CVS48_RS07615 22814c76f0031d44cf739f1abc68f465 485 Gene3D G3DSA:1.10.10.410 423 484 3.3E-23 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CVS48_RS07615 22814c76f0031d44cf739f1abc68f465 485 SMART SM00845 332 483 4.4E-78 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CVS48_RS07615 22814c76f0031d44cf739f1abc68f465 485 Pfam PF02934 GatB/GatE catalytic domain 5 292 1.2E-109 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CVS48_RS07615 22814c76f0031d44cf739f1abc68f465 485 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 148 162 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CVS48_RS07615 22814c76f0031d44cf739f1abc68f465 485 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 484 37.488 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CVS48_RS07615 22814c76f0031d44cf739f1abc68f465 485 Pfam PF02637 GatB domain 333 483 6.3E-50 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CVS48_RS07615 22814c76f0031d44cf739f1abc68f465 485 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 483 1.0E-163 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CVS48_RS23745 ac8699ab7a9ac800ac44065405c30aad 378 Gene3D G3DSA:1.20.5.70 352 377 1.1E-7 T 29-03-2018 CVS48_RS23745 ac8699ab7a9ac800ac44065405c30aad 378 Gene3D G3DSA:3.10.560.10 261 351 2.2E-17 T 29-03-2018 CVS48_RS23745 ac8699ab7a9ac800ac44065405c30aad 378 Gene3D G3DSA:3.10.560.10 172 260 7.2E-24 T 29-03-2018 CVS48_RS23745 ac8699ab7a9ac800ac44065405c30aad 378 Pfam PF02563 Polysaccharide biosynthesis/export protein 80 176 2.0E-25 T 29-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 CVS48_RS23745 ac8699ab7a9ac800ac44065405c30aad 378 Pfam PF10531 SLBB domain 267 313 0.0021 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS23745 ac8699ab7a9ac800ac44065405c30aad 378 Pfam PF10531 SLBB domain 183 234 1.4E-9 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS23745 ac8699ab7a9ac800ac44065405c30aad 378 Gene3D G3DSA:3.30.1950.10 87 171 7.6E-22 T 29-03-2018 CVS48_RS04305 071b8606de9070aacd6e1661e0c66c82 476 Pfam PF12390 Selenocysteine synthase N terminal 15 52 3.0E-5 T 29-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CVS48_RS04305 071b8606de9070aacd6e1661e0c66c82 476 Pfam PF03841 L-seryl-tRNA selenium transferase 89 459 6.5E-161 T 29-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CVS48_RS04305 071b8606de9070aacd6e1661e0c66c82 476 SUPERFAMILY SSF53383 81 353 9.95E-44 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS04305 071b8606de9070aacd6e1661e0c66c82 476 Gene3D G3DSA:3.40.640.10 101 362 1.8E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS04305 071b8606de9070aacd6e1661e0c66c82 476 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 15 472 5.4E-179 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CVS48_RS04305 071b8606de9070aacd6e1661e0c66c82 476 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 476 231.315 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CVS48_RS22420 df0e3e94b55d12014c0c9be2fb3a54d5 81 PRINTS PR00050 Cold shock protein signature 39 48 3.1E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS22420 df0e3e94b55d12014c0c9be2fb3a54d5 81 PRINTS PR00050 Cold shock protein signature 54 72 3.1E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS22420 df0e3e94b55d12014c0c9be2fb3a54d5 81 PRINTS PR00050 Cold shock protein signature 18 33 3.1E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS22420 df0e3e94b55d12014c0c9be2fb3a54d5 81 ProSitePatterns PS00352 'Cold-shock' domain signature. 29 48 - T 29-03-2018 IPR019844 Cold-shock conserved site CVS48_RS22420 df0e3e94b55d12014c0c9be2fb3a54d5 81 Gene3D G3DSA:2.40.50.140 8 81 1.3E-29 T 29-03-2018 CVS48_RS22420 df0e3e94b55d12014c0c9be2fb3a54d5 81 SMART SM00357 17 81 2.3E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CVS48_RS22420 df0e3e94b55d12014c0c9be2fb3a54d5 81 PIRSF PIRSF002599 12 81 6.4E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CVS48_RS22420 df0e3e94b55d12014c0c9be2fb3a54d5 81 Pfam PF00313 'Cold-shock' DNA-binding domain 17 80 3.1E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS22420 df0e3e94b55d12014c0c9be2fb3a54d5 81 SUPERFAMILY SSF50249 15 79 2.36E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 Gene3D G3DSA:1.10.10.10 1 89 4.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 Pfam PF03466 LysR substrate binding domain 89 286 2.6E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 Gene3D G3DSA:3.40.190.10 180 260 1.6E-18 T 29-03-2018 CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 SUPERFAMILY SSF53850 92 293 7.45E-36 T 29-03-2018 CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 SUPERFAMILY SSF46785 1 87 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 Gene3D G3DSA:3.40.190.10 91 179 7.4E-20 T 29-03-2018 CVS48_RS18655 186486fa6344cbc20bd92ec1ccfb77a8 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 1.6E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 Pfam PF00732 GMC oxidoreductase 4 293 1.8E-81 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 252 266 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 81 104 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 SUPERFAMILY SSF54373 288 471 1.86E-55 T 29-03-2018 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 Gene3D G3DSA:4.10.450.10 35 103 5.5E-27 T 29-03-2018 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 PIRSF PIRSF000137 1 532 4.7E-143 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 Gene3D G3DSA:3.30.560.10 104 483 1.7E-98 T 29-03-2018 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 SUPERFAMILY SSF51905 3 286 2.43E-78 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 SUPERFAMILY SSF51905 470 529 2.43E-78 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14185 0961e5968b5d27184a128a1119fed768 532 Pfam PF05199 GMC oxidoreductase 385 520 3.0E-39 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS18760 502c8ce771d2529bb48747422d737745 214 Gene3D G3DSA:3.40.470.10 16 209 7.3E-54 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS18760 502c8ce771d2529bb48747422d737745 214 SUPERFAMILY SSF52141 23 199 9.48E-50 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS18760 502c8ce771d2529bb48747422d737745 214 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 21 201 4.8E-72 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 CVS48_RS18760 502c8ce771d2529bb48747422d737745 214 SMART SM00986 41 198 3.5E-30 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS18760 502c8ce771d2529bb48747422d737745 214 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 27 188 1.3E-38 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 CVS48_RS18760 502c8ce771d2529bb48747422d737745 214 SMART SM00987 41 198 3.5E-30 T 29-03-2018 CVS48_RS18760 502c8ce771d2529bb48747422d737745 214 Pfam PF03167 Uracil DNA glycosylase superfamily 42 194 8.7E-36 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 SMART SM00345 20 78 3.6E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 Pfam PF07729 FCD domain 93 217 4.2E-21 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 SUPERFAMILY SSF48008 94 227 7.32E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 6.0E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 6.0E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 SUPERFAMILY SSF46785 18 88 1.82E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 Gene3D G3DSA:1.10.10.10 1 74 7.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 Gene3D G3DSA:1.20.120.530 75 236 7.2E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 SMART SM00895 88 219 2.1E-15 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS09880 4762778cf8cc91095c027d86958f347f 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 2.0E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 66 77 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 77 87 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 87 98 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 Gene3D G3DSA:3.40.190.10 135 225 9.3E-17 T 29-03-2018 CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 Gene3D G3DSA:1.10.10.10 46 131 2.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 SUPERFAMILY SSF53850 139 345 3.12E-28 T 29-03-2018 CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 Gene3D G3DSA:3.40.190.10 226 314 6.2E-13 T 29-03-2018 CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 Pfam PF03466 LysR substrate binding domain 138 341 3.2E-27 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 56 109 7.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21290 23364561a391ef21417c034f4931bbcf 350 SUPERFAMILY SSF46785 41 158 2.84E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15215 f77fd5526d7cc2818ff2fa8fa7bbab78 273 Pfam PF12697 Alpha/beta hydrolase family 25 260 4.0E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS15215 f77fd5526d7cc2818ff2fa8fa7bbab78 273 SUPERFAMILY SSF53474 13 268 6.54E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS15215 f77fd5526d7cc2818ff2fa8fa7bbab78 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 5.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS15215 f77fd5526d7cc2818ff2fa8fa7bbab78 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 5.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS15215 f77fd5526d7cc2818ff2fa8fa7bbab78 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 5.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS15215 f77fd5526d7cc2818ff2fa8fa7bbab78 273 PRINTS PR00412 Epoxide hydrolase signature 48 63 3.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS15215 f77fd5526d7cc2818ff2fa8fa7bbab78 273 PRINTS PR00412 Epoxide hydrolase signature 104 117 3.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS15215 f77fd5526d7cc2818ff2fa8fa7bbab78 273 PRINTS PR00412 Epoxide hydrolase signature 243 265 3.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS15215 f77fd5526d7cc2818ff2fa8fa7bbab78 273 Gene3D G3DSA:3.40.50.1820 5 269 8.3E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 204 271 1.7E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 427 1.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 SUPERFAMILY SSF55874 262 425 3.14E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 Gene3D G3DSA:3.30.565.10 275 434 5.0E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 3.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 3.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 3.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 3.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 Pfam PF11808 Domain of unknown function (DUF3329) 3 83 2.4E-12 T 29-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 94 424 1.3E-123 T 29-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 SUPERFAMILY SSF55785 87 176 1.33E-5 T 29-03-2018 IPR000014 PAS domain CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 SMART SM00387 315 428 1.4E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 SMART SM00388 203 272 3.9E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 SUPERFAMILY SSF47384 190 271 2.94E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 Gene3D G3DSA:3.30.450.20 79 199 4.4E-9 T 29-03-2018 CVS48_RS03755 a608104c67a9cf55976691164c77b3e0 435 Gene3D G3DSA:1.10.287.130 200 267 1.3E-20 T 29-03-2018 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 Gene3D G3DSA:1.10.150.20 174 246 2.0E-25 T 29-03-2018 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 Pfam PF11799 impB/mucB/samB family C-terminal domain 238 351 1.7E-17 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 Pfam PF00817 impB/mucB/samB family 11 157 3.3E-53 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 Gene3D G3DSA:3.30.70.270 44 116 5.8E-26 T 29-03-2018 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 Gene3D G3DSA:3.30.70.270 117 173 3.7E-24 T 29-03-2018 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 SUPERFAMILY SSF56672 3 237 2.4E-99 T 29-03-2018 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 Hamap MF_01113 DNA polymerase IV [dinB]. 5 355 37.771 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 Gene3D G3DSA:3.30.1490.100 247 352 1.5E-19 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 SUPERFAMILY SSF100879 243 342 5.3E-19 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CVS48_RS15390 dabf8c3d17ed8489fa24a4934b442096 360 Pfam PF11798 IMS family HHH motif 169 200 4.9E-10 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 Pfam PF14841 FliG middle domain 119 192 2.3E-24 T 29-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 Gene3D G3DSA:1.10.220.30 11 72 3.8E-10 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 PIRSF PIRSF003161 2 336 7.4E-117 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 251 271 2.9E-66 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 275 301 2.9E-66 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 8 24 2.9E-66 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 229 249 2.9E-66 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 37 63 2.9E-66 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 198 223 2.9E-66 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 118 141 2.9E-66 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 SUPERFAMILY SSF48029 9 105 1.15E-19 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 Pfam PF01706 FliG C-terminal domain 221 327 2.5E-40 T 29-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 Gene3D G3DSA:1.10.220.30 198 336 2.9E-33 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 Gene3D G3DSA:1.10.220.30 73 194 1.8E-18 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 7 335 4.2E-120 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 Pfam PF14842 FliG N-terminal domain 8 104 3.2E-29 T 29-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CVS48_RS16995 991c7cbb9c6008dc6e9a2dda7f5c3913 336 SUPERFAMILY SSF48029 118 328 2.35E-65 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CVS48_RS28120 863b9f7adcc20b66f95268535f49b131 527 PIRSF PIRSF002741 10 525 1.6E-77 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS28120 863b9f7adcc20b66f95268535f49b131 527 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 436 7.6E-69 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS28120 863b9f7adcc20b66f95268535f49b131 527 Gene3D G3DSA:3.90.76.10 50 198 4.7E-30 T 29-03-2018 CVS48_RS28120 863b9f7adcc20b66f95268535f49b131 527 Gene3D G3DSA:3.10.105.10 300 499 2.3E-33 T 29-03-2018 CVS48_RS28120 863b9f7adcc20b66f95268535f49b131 527 SUPERFAMILY SSF53850 48 524 9.45E-99 T 29-03-2018 CVS48_RS28120 863b9f7adcc20b66f95268535f49b131 527 Gene3D G3DSA:3.40.190.10 199 299 1.9E-15 T 29-03-2018 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 PIRSF PIRSF016578 5 92 1.7 T 29-03-2018 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 PIRSF PIRSF016578 242 384 2.1E-7 T 29-03-2018 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 PIRSF PIRSF016578 121 230 1.0E-4 T 29-03-2018 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 Gene3D G3DSA:2.40.110.10 131 225 1.9E-29 T 29-03-2018 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 126 1.3E-12 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 SUPERFAMILY SSF56645 12 246 1.44E-55 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 Gene3D G3DSA:1.10.540.10 8 130 3.8E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 384 1.5E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 SUPERFAMILY SSF47203 233 385 1.34E-44 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 Gene3D G3DSA:1.20.140.10 226 387 1.3E-44 T 29-03-2018 CVS48_RS09765 402c0c95543c9d7550c931736438d0b9 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 223 1.5E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS26435 baedaee22f3070392fe023e280d487f1 245 Gene3D G3DSA:3.30.1330.30 1 77 1.8E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CVS48_RS26435 baedaee22f3070392fe023e280d487f1 245 SUPERFAMILY SSF55315 3 77 8.36E-19 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CVS48_RS26435 baedaee22f3070392fe023e280d487f1 245 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 243 8.2E-73 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CVS48_RS26435 baedaee22f3070392fe023e280d487f1 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 80 1.3E-17 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CVS48_RS26435 baedaee22f3070392fe023e280d487f1 245 Pfam PF00588 SpoU rRNA Methylase family 97 237 1.4E-39 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CVS48_RS26435 baedaee22f3070392fe023e280d487f1 245 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 244 44.425 T 29-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB CVS48_RS26435 baedaee22f3070392fe023e280d487f1 245 Gene3D G3DSA:3.40.1280.10 78 244 2.9E-46 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CVS48_RS26435 baedaee22f3070392fe023e280d487f1 245 SMART SM00967 6 82 3.5E-19 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CVS48_RS26435 baedaee22f3070392fe023e280d487f1 245 SUPERFAMILY SSF75217 83 243 9.16E-49 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CVS48_RS07795 7a3f33f0e04982d2fd60568adaffd7cd 384 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 12 368 5.2E-100 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CVS48_RS07795 7a3f33f0e04982d2fd60568adaffd7cd 384 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 7 378 2.6E-132 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CVS48_RS07795 7a3f33f0e04982d2fd60568adaffd7cd 384 PIRSF PIRSF000267 7 382 4.7E-115 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CVS48_RS25485 ba92106c541ffb30797f88d3a7f54b0e 191 SUPERFAMILY SSF88946 7 92 3.1E-10 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25485 ba92106c541ffb30797f88d3a7f54b0e 191 Pfam PF04542 Sigma-70 region 2 18 79 5.0E-7 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25485 ba92106c541ffb30797f88d3a7f54b0e 191 Gene3D G3DSA:1.10.10.10 75 168 3.0E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25485 ba92106c541ffb30797f88d3a7f54b0e 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 166 7.1E-20 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25485 ba92106c541ffb30797f88d3a7f54b0e 191 Pfam PF08281 Sigma-70, region 4 110 162 2.3E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25485 ba92106c541ffb30797f88d3a7f54b0e 191 Gene3D G3DSA:1.10.1740.10 2 74 1.7E-10 T 29-03-2018 CVS48_RS25485 ba92106c541ffb30797f88d3a7f54b0e 191 SUPERFAMILY SSF88659 92 165 3.05E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS06410 3612a28e6ac3e1c25461f40a0c6c205a 109 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06410 3612a28e6ac3e1c25461f40a0c6c205a 109 Gene3D G3DSA:3.90.470.10 1 109 3.2E-39 T 29-03-2018 CVS48_RS06410 3612a28e6ac3e1c25461f40a0c6c205a 109 SUPERFAMILY SSF54843 1 107 5.49E-39 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CVS48_RS06410 3612a28e6ac3e1c25461f40a0c6c205a 109 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 23.892 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06410 3612a28e6ac3e1c25461f40a0c6c205a 109 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 4.4E-43 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06410 3612a28e6ac3e1c25461f40a0c6c205a 109 Pfam PF00237 Ribosomal protein L22p/L17e 7 107 9.1E-35 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CVS48_RS16680 3597ce6fa2207a9eeca38e08b53f95ef 902 Gene3D G3DSA:3.40.50.920 718 902 7.9E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS16680 3597ce6fa2207a9eeca38e08b53f95ef 902 SUPERFAMILY SSF52518 64 477 4.13E-136 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS16680 3597ce6fa2207a9eeca38e08b53f95ef 902 SUPERFAMILY SSF52922 715 901 6.91E-59 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS16680 3597ce6fa2207a9eeca38e08b53f95ef 902 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 12 901 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CVS48_RS16680 3597ce6fa2207a9eeca38e08b53f95ef 902 PIRSF PIRSF000156 3 902 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CVS48_RS16680 3597ce6fa2207a9eeca38e08b53f95ef 902 SUPERFAMILY SSF52518 483 711 1.18E-96 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS16680 3597ce6fa2207a9eeca38e08b53f95ef 902 Gene3D G3DSA:3.40.50.970 482 717 4.9E-65 T 29-03-2018 CVS48_RS16680 3597ce6fa2207a9eeca38e08b53f95ef 902 Gene3D G3DSA:3.40.50.970 63 481 6.2E-85 T 29-03-2018 CVS48_RS16680 3597ce6fa2207a9eeca38e08b53f95ef 902 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 147 302 5.0E-9 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS14010 b81516d269030c66c7ecf84871a42da0 302 SUPERFAMILY SSF53850 91 299 3.44E-33 T 29-03-2018 CVS48_RS14010 b81516d269030c66c7ecf84871a42da0 302 SUPERFAMILY SSF46785 4 111 6.35E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14010 b81516d269030c66c7ecf84871a42da0 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 5.4E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS14010 b81516d269030c66c7ecf84871a42da0 302 Gene3D G3DSA:1.10.10.10 1 86 4.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14010 b81516d269030c66c7ecf84871a42da0 302 Gene3D G3DSA:3.40.190.10 91 179 2.2E-16 T 29-03-2018 CVS48_RS14010 b81516d269030c66c7ecf84871a42da0 302 Pfam PF03466 LysR substrate binding domain 90 297 1.8E-27 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS14010 b81516d269030c66c7ecf84871a42da0 302 Gene3D G3DSA:3.40.190.10 180 268 4.6E-16 T 29-03-2018 CVS48_RS10670 d2a3a5f81143688725ace317902a298c 221 Gene3D G3DSA:1.20.1260.10 49 194 3.3E-22 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS10670 d2a3a5f81143688725ace317902a298c 221 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 61 221 2.0E-41 T 29-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 CVS48_RS10670 d2a3a5f81143688725ace317902a298c 221 SUPERFAMILY SSF47240 55 135 1.79E-17 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS10670 d2a3a5f81143688725ace317902a298c 221 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 20 221 31.054 T 29-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 CVS48_RS13450 47ee5c3efcc03b5498f2ba028c8fc490 332 PIRSF PIRSF017082 1 332 1.8E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13450 47ee5c3efcc03b5498f2ba028c8fc490 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 328 8.8E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13450 47ee5c3efcc03b5498f2ba028c8fc490 332 SUPERFAMILY SSF53850 126 292 9.96E-12 T 29-03-2018 CVS48_RS13450 47ee5c3efcc03b5498f2ba028c8fc490 332 Gene3D G3DSA:3.40.190.10 133 244 1.3E-9 T 29-03-2018 CVS48_RS25405 f029b91564b27e997678444940b79fba 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 276 5.1E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS25405 f029b91564b27e997678444940b79fba 280 Gene3D G3DSA:1.10.3720.10 6 280 3.2E-24 T 29-03-2018 CVS48_RS25405 f029b91564b27e997678444940b79fba 280 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 73 270 9.8E-72 T 29-03-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 CVS48_RS25405 f029b91564b27e997678444940b79fba 280 SUPERFAMILY SSF161098 84 269 2.35E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18130 a46d61ab1b81eba944040077b4695f78 527 Gene3D G3DSA:3.40.309.10 280 457 1.7E-20 T 29-03-2018 CVS48_RS18130 a46d61ab1b81eba944040077b4695f78 527 Gene3D G3DSA:3.40.605.10 3 279 1.2E-52 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS18130 a46d61ab1b81eba944040077b4695f78 527 Pfam PF00171 Aldehyde dehydrogenase family 21 469 1.7E-47 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS18130 a46d61ab1b81eba944040077b4695f78 527 SUPERFAMILY SSF53720 18 521 3.27E-100 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 SUPERFAMILY SSF82714 183 264 2.22E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 Gene3D G3DSA:1.20.1640.10 785 1006 1.4E-40 T 29-03-2018 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 Gene3D G3DSA:3.30.2090.10 698 784 2.6E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 SUPERFAMILY SSF82693 43 130 2.27E-24 T 29-03-2018 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 SUPERFAMILY SSF82693 267 320 2.49E-17 T 29-03-2018 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 SUPERFAMILY SSF82693 137 181 2.49E-17 T 29-03-2018 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 SUPERFAMILY SSF82866 296 489 1.57E-47 T 29-03-2018 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 SUPERFAMILY SSF82866 784 1005 7.06E-42 T 29-03-2018 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 Gene3D G3DSA:3.30.70.1430 555 647 2.3E-5 T 29-03-2018 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 1.2E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 1.2E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 1.2E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 1.2E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 1.2E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 1.2E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 Pfam PF00873 AcrB/AcrD/AcrF family 4 1003 2.2E-265 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 Gene3D G3DSA:1.20.1640.10 286 498 2.5E-42 T 29-03-2018 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 Gene3D G3DSA:3.30.2090.10 180 268 1.3E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 SUPERFAMILY SSF82693 553 650 6.8E-15 T 29-03-2018 CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 SUPERFAMILY SSF82714 699 786 6.54E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS28770 50e501f3762e563d987a6a098513478a 1033 Gene3D G3DSA:3.30.70.1430 41 141 1.1E-25 T 29-03-2018 CVS48_RS16880 cff009e7420f9cee8156422d2eb12b3e 253 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 173 248 1.2E-16 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CVS48_RS16880 cff009e7420f9cee8156422d2eb12b3e 253 SUPERFAMILY SSF117143 78 211 6.41E-14 T 29-03-2018 CVS48_RS16880 cff009e7420f9cee8156422d2eb12b3e 253 Pfam PF00460 Flagella basal body rod protein 5 35 3.3E-5 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CVS48_RS16880 cff009e7420f9cee8156422d2eb12b3e 253 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CVS48_RS16880 cff009e7420f9cee8156422d2eb12b3e 253 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 122 1.4E-28 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CVS48_RS25110 e6aa50f20a4cdd31cb7550310950d1b3 283 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 260 9.7E-53 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS25110 e6aa50f20a4cdd31cb7550310950d1b3 283 Gene3D G3DSA:3.90.226.10 1 281 8.1E-79 T 29-03-2018 CVS48_RS25110 e6aa50f20a4cdd31cb7550310950d1b3 283 SUPERFAMILY SSF52096 1 267 1.17E-78 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS08295 a19427871518808c86915812562cde9d 758 Gene3D G3DSA:3.40.50.10810 49 464 2.1E-25 T 29-03-2018 CVS48_RS08295 a19427871518808c86915812562cde9d 758 SMART SM00487 63 426 2.7E-7 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS08295 a19427871518808c86915812562cde9d 758 Gene3D G3DSA:3.40.50.300 574 732 1.4E-14 T 29-03-2018 CVS48_RS08295 a19427871518808c86915812562cde9d 758 SUPERFAMILY SSF52540 53 174 2.42E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08295 a19427871518808c86915812562cde9d 758 SUPERFAMILY SSF52540 344 411 2.42E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08295 a19427871518808c86915812562cde9d 758 SUPERFAMILY SSF52540 492 735 3.19E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08295 a19427871518808c86915812562cde9d 758 Pfam PF00271 Helicase conserved C-terminal domain 592 695 2.6E-4 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS08295 a19427871518808c86915812562cde9d 758 Pfam PF04851 Type III restriction enzyme, res subunit 67 141 5.2E-5 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 SMART SM00345 38 97 2.8E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 SMART SM00866 118 259 5.2E-9 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 SUPERFAMILY SSF64288 85 265 1.19E-26 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 Pfam PF00392 Bacterial regulatory proteins, gntR family 35 97 7.7E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 Gene3D G3DSA:1.10.10.10 25 99 6.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 87 1.8E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 71 1.8E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 Gene3D G3DSA:3.40.1410.10 101 266 4.7E-21 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 Pfam PF07702 UTRA domain 129 259 2.1E-13 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS05880 e92b18d75d0a8aea3849652664a7b25a 267 SUPERFAMILY SSF46785 27 101 3.94E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 Pfam PF02040 Arsenical pump membrane protein 4 424 3.2E-160 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 425 1.5E-216 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 8.6E-114 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 8.6E-114 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 8.6E-114 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 8.6E-114 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 8.6E-114 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 8.6E-114 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 8.6E-114 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS18595 455399c30965f5454eb491e1bb1bae28 426 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 8.6E-114 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS07470 73d7574a284617aee464b378d1e93602 598 SMART SM00490 259 340 6.0E-31 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS07470 73d7574a284617aee464b378d1e93602 598 Gene3D G3DSA:3.40.50.300 222 559 4.3E-45 T 29-03-2018 CVS48_RS07470 73d7574a284617aee464b378d1e93602 598 SUPERFAMILY SSF52540 73 361 3.34E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07470 73d7574a284617aee464b378d1e93602 598 Gene3D G3DSA:3.40.50.300 6 221 2.7E-60 T 29-03-2018 CVS48_RS07470 73d7574a284617aee464b378d1e93602 598 SMART SM00487 20 222 4.1E-58 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS07470 73d7574a284617aee464b378d1e93602 598 Pfam PF00270 DEAD/DEAH box helicase 25 195 2.6E-48 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS07470 73d7574a284617aee464b378d1e93602 598 Pfam PF00271 Helicase conserved C-terminal domain 234 340 4.6E-27 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS07470 73d7574a284617aee464b378d1e93602 598 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CVS48_RS10150 0767d9df49ceef7c759cd88311a0f7fe 236 Gene3D G3DSA:1.20.120.530 83 235 6.7E-38 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS10150 0767d9df49ceef7c759cd88311a0f7fe 236 SMART SM00895 90 217 4.0E-27 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS10150 0767d9df49ceef7c759cd88311a0f7fe 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 80 3.4E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10150 0767d9df49ceef7c759cd88311a0f7fe 236 SMART SM00345 22 80 2.4E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10150 0767d9df49ceef7c759cd88311a0f7fe 236 Pfam PF07729 FCD domain 90 216 9.4E-30 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS10150 0767d9df49ceef7c759cd88311a0f7fe 236 SUPERFAMILY SSF48008 85 219 2.25E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS10150 0767d9df49ceef7c759cd88311a0f7fe 236 Gene3D G3DSA:1.10.10.10 10 82 3.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10150 0767d9df49ceef7c759cd88311a0f7fe 236 SUPERFAMILY SSF46785 14 108 2.13E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 Gene3D G3DSA:3.40.190.10 182 272 3.4E-18 T 29-03-2018 CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 Gene3D G3DSA:3.40.190.10 91 181 1.8E-20 T 29-03-2018 CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 SUPERFAMILY SSF53850 92 304 1.09E-37 T 29-03-2018 CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 Gene3D G3DSA:1.10.10.10 1 83 1.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 Pfam PF03466 LysR substrate binding domain 90 297 1.8E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 SUPERFAMILY SSF46785 13 112 8.71E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28180 0b12570b23700797643dc1d64ea9dc98 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 4.3E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17210 38f84904e92cd65d0be345909f335801 275 Gene3D G3DSA:3.40.50.300 20 272 0.0064 T 29-03-2018 CVS48_RS17210 38f84904e92cd65d0be345909f335801 275 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 7 275 73.862 T 29-03-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein CVS48_RS17210 38f84904e92cd65d0be345909f335801 275 Pfam PF03618 Kinase/pyrophosphorylase 10 267 3.9E-79 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CVS48_RS03015 fa40dbb094693c4597e4317402b8a139 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 3.2E-62 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS03015 fa40dbb094693c4597e4317402b8a139 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.809 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CVS48_RS03015 fa40dbb094693c4597e4317402b8a139 142 SUPERFAMILY SSF52161 1 139 2.35E-59 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CVS48_RS03015 fa40dbb094693c4597e4317402b8a139 142 PIRSF PIRSF002181 1 142 2.3E-48 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CVS48_RS03015 fa40dbb094693c4597e4317402b8a139 142 Pfam PF00572 Ribosomal protein L13 15 138 1.6E-55 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CVS48_RS03015 fa40dbb094693c4597e4317402b8a139 142 Gene3D G3DSA:3.90.1180.10 1 142 3.5E-61 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CVS48_RS00235 33fe053402ff9d0b4c1f180c1d976453 290 Pfam PF01380 SIS domain 130 253 3.4E-18 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CVS48_RS00235 33fe053402ff9d0b4c1f180c1d976453 290 SUPERFAMILY SSF46689 5 77 5.55E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS00235 33fe053402ff9d0b4c1f180c1d976453 290 Gene3D G3DSA:1.10.10.10 4 95 1.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00235 33fe053402ff9d0b4c1f180c1d976453 290 SUPERFAMILY SSF53697 99 280 1.96E-36 T 29-03-2018 CVS48_RS00235 33fe053402ff9d0b4c1f180c1d976453 290 Gene3D G3DSA:3.40.50.10490 96 282 9.0E-37 T 29-03-2018 CVS48_RS00235 33fe053402ff9d0b4c1f180c1d976453 290 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 77 4.5E-12 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 8 370 9.4E-92 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 Gene3D G3DSA:3.10.150.10 2 125 3.0E-23 T 29-03-2018 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 250 370 1.6E-29 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 9 122 2.8E-26 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 Gene3D G3DSA:3.10.150.10 128 251 9.9E-32 T 29-03-2018 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 SUPERFAMILY SSF55979 8 120 1.6E-21 T 29-03-2018 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 Gene3D G3DSA:3.10.150.10 252 371 3.9E-23 T 29-03-2018 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 SUPERFAMILY SSF55979 129 248 3.14E-29 T 29-03-2018 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 SMART SM00480 20 367 2.7E-100 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 SUPERFAMILY SSF55979 250 371 1.95E-32 T 29-03-2018 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 134 247 2.7E-33 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS06030 1de4ff23eeabac49b597e8d99bd3f87e 371 PIRSF PIRSF000804 3 371 8.1E-110 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS25660 d8c4b3267f831d4c186b2d8cfad9d97d 339 PRINTS PR01713 Nucleotide sugar epimerase signature 240 255 9.3E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS25660 d8c4b3267f831d4c186b2d8cfad9d97d 339 PRINTS PR01713 Nucleotide sugar epimerase signature 279 296 9.3E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS25660 d8c4b3267f831d4c186b2d8cfad9d97d 339 PRINTS PR01713 Nucleotide sugar epimerase signature 217 232 9.3E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS25660 d8c4b3267f831d4c186b2d8cfad9d97d 339 Gene3D G3DSA:3.90.25.10 182 331 6.2E-41 T 29-03-2018 CVS48_RS25660 d8c4b3267f831d4c186b2d8cfad9d97d 339 Gene3D G3DSA:3.40.50.720 5 181 1.8E-31 T 29-03-2018 CVS48_RS25660 d8c4b3267f831d4c186b2d8cfad9d97d 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 11 308 9.9E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25660 d8c4b3267f831d4c186b2d8cfad9d97d 339 SUPERFAMILY SSF51735 7 316 1.1E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19675 02e72938e9e94e89fe571aca48c5d2cd 319 Pfam PF00892 EamA-like transporter family 164 294 7.6E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS19675 02e72938e9e94e89fe571aca48c5d2cd 319 Pfam PF00892 EamA-like transporter family 22 154 4.2E-8 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS19675 02e72938e9e94e89fe571aca48c5d2cd 319 SUPERFAMILY SSF103481 64 158 7.19E-9 T 29-03-2018 CVS48_RS19675 02e72938e9e94e89fe571aca48c5d2cd 319 SUPERFAMILY SSF103481 205 303 2.75E-14 T 29-03-2018 CVS48_RS19970 0d1fbc7e8c32dde9364012409f10119f 225 Pfam PF04367 Protein of unknown function (DUF502) 56 160 6.9E-24 T 29-03-2018 IPR007462 Protein of unknown function DUF502 CVS48_RS05815 4d38a3705a49e9a1f8016c13d2ac45d3 509 SUPERFAMILY SSF52540 7 228 1.46E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05815 4d38a3705a49e9a1f8016c13d2ac45d3 509 Gene3D G3DSA:3.40.50.300 241 498 1.0E-31 T 29-03-2018 CVS48_RS05815 4d38a3705a49e9a1f8016c13d2ac45d3 509 SUPERFAMILY SSF52540 257 495 1.03E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05815 4d38a3705a49e9a1f8016c13d2ac45d3 509 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05815 4d38a3705a49e9a1f8016c13d2ac45d3 509 SMART SM00382 32 219 2.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05815 4d38a3705a49e9a1f8016c13d2ac45d3 509 Pfam PF00005 ABC transporter 279 436 1.6E-13 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05815 4d38a3705a49e9a1f8016c13d2ac45d3 509 Pfam PF00005 ABC transporter 24 172 5.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05815 4d38a3705a49e9a1f8016c13d2ac45d3 509 Gene3D G3DSA:3.40.50.300 5 240 1.0E-50 T 29-03-2018 CVS48_RS05815 4d38a3705a49e9a1f8016c13d2ac45d3 509 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS22220 5ed06989125aa16d5e647d309461e261 764 SUPERFAMILY SSF52540 3 506 7.84E-177 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22220 5ed06989125aa16d5e647d309461e261 764 SUPERFAMILY SSF52540 542 657 7.84E-177 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22220 5ed06989125aa16d5e647d309461e261 764 Gene3D G3DSA:3.40.50.300 277 379 3.7E-25 T 29-03-2018 CVS48_RS22220 5ed06989125aa16d5e647d309461e261 764 Gene3D G3DSA:3.40.50.300 388 668 1.2E-48 T 29-03-2018 CVS48_RS22220 5ed06989125aa16d5e647d309461e261 764 Pfam PF13361 UvrD-like helicase C-terminal domain 272 632 9.4E-70 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CVS48_RS22220 5ed06989125aa16d5e647d309461e261 764 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 266 6.1E-74 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CVS48_RS22220 5ed06989125aa16d5e647d309461e261 764 Gene3D G3DSA:3.40.50.300 140 276 2.3E-32 T 29-03-2018 CVS48_RS22220 5ed06989125aa16d5e647d309461e261 764 Gene3D G3DSA:3.40.50.300 1 139 2.3E-25 T 29-03-2018 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 SMART SM00448 6 122 2.0E-10 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 Pfam PF00072 Response regulator receiver domain 8 122 7.7E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.3E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.3E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.3E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 SMART SM00421 149 206 5.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 SUPERFAMILY SSF46894 143 206 1.7E-14 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 Gene3D G3DSA:3.40.50.2300 5 132 5.1E-20 T 29-03-2018 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 SUPERFAMILY SSF52172 6 141 8.68E-21 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 2.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS24950 02f09c8c9bca78df276745ecdbaebf69 233 Gene3D G3DSA:1.10.10.10 133 213 6.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16360 9aba34f3e48fe8a07103b2e96e4d18cc 319 SUPERFAMILY SSF51679 5 307 5.76E-57 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CVS48_RS16360 9aba34f3e48fe8a07103b2e96e4d18cc 319 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 1 306 2.9E-114 T 29-03-2018 IPR020020 Luciferase-type oxidoreductase CVS48_RS16360 9aba34f3e48fe8a07103b2e96e4d18cc 319 Gene3D G3DSA:3.20.20.30 1 308 7.8E-57 T 29-03-2018 CVS48_RS16360 9aba34f3e48fe8a07103b2e96e4d18cc 319 Pfam PF00296 Luciferase-like monooxygenase 8 220 1.2E-40 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CVS48_RS09120 76b235c3ebebac4db2885b42a981ffb5 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 486 2.4E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS09120 76b235c3ebebac4db2885b42a981ffb5 501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS09120 76b235c3ebebac4db2885b42a981ffb5 501 SUPERFAMILY SSF56801 4 498 2.88E-129 T 29-03-2018 CVS48_RS09120 76b235c3ebebac4db2885b42a981ffb5 501 Gene3D G3DSA:2.30.38.10 312 395 6.8E-20 T 29-03-2018 CVS48_RS09120 76b235c3ebebac4db2885b42a981ffb5 501 Gene3D G3DSA:3.30.300.30 397 501 2.2E-26 T 29-03-2018 CVS48_RS09120 76b235c3ebebac4db2885b42a981ffb5 501 Gene3D G3DSA:3.40.50.980 4 162 4.5E-30 T 29-03-2018 CVS48_RS09120 76b235c3ebebac4db2885b42a981ffb5 501 Gene3D G3DSA:3.40.50.980 163 311 2.7E-32 T 29-03-2018 CVS48_RS09120 76b235c3ebebac4db2885b42a981ffb5 501 Pfam PF00501 AMP-binding enzyme 7 402 2.8E-79 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS28370 e6946e9a4a1c5743130f29432498127b 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 89 178 2.2E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS28370 e6946e9a4a1c5743130f29432498127b 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 183 3.8E-35 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS28370 e6946e9a4a1c5743130f29432498127b 221 SUPERFAMILY SSF56784 2 213 3.8E-56 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS28370 e6946e9a4a1c5743130f29432498127b 221 Gene3D G3DSA:3.40.50.1000 73 221 8.9E-32 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS28370 e6946e9a4a1c5743130f29432498127b 221 Gene3D G3DSA:1.10.150.240 30 72 4.6E-14 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CVS48_RS28370 e6946e9a4a1c5743130f29432498127b 221 Gene3D G3DSA:3.40.50.1000 1 29 0.092 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS28370 e6946e9a4a1c5743130f29432498127b 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 120 183 8.5E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 SMART SM00895 92 218 1.0E-15 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 Gene3D G3DSA:1.20.120.530 85 235 4.2E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 SUPERFAMILY SSF48008 88 225 4.97E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 SUPERFAMILY SSF46785 5 78 1.18E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.5E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.5E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 Gene3D G3DSA:1.10.10.10 3 76 1.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 SMART SM00345 15 74 2.4E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 1.3E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11070 ecc4e9ac105f3213e28a7d8d0f07ab70 244 Pfam PF07729 FCD domain 93 216 2.4E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS06555 7f0814ecacf109f7cc9ba77bf5394cfe 121 PIRSF PIRSF002134 1 121 5.4E-39 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06555 7f0814ecacf109f7cc9ba77bf5394cfe 121 Gene3D G3DSA:1.10.8.50 1 66 7.0E-21 T 29-03-2018 CVS48_RS06555 7f0814ecacf109f7cc9ba77bf5394cfe 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 5.9E-30 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06555 7f0814ecacf109f7cc9ba77bf5394cfe 121 SUPERFAMILY SSF46946 2 114 6.67E-42 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CVS48_RS06555 7f0814ecacf109f7cc9ba77bf5394cfe 121 Gene3D G3DSA:4.10.910.10 67 85 3.2E-16 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06555 7f0814ecacf109f7cc9ba77bf5394cfe 121 Gene3D G3DSA:4.10.910.10 86 121 5.7E-24 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06555 7f0814ecacf109f7cc9ba77bf5394cfe 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06555 7f0814ecacf109f7cc9ba77bf5394cfe 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 26.376 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06555 7f0814ecacf109f7cc9ba77bf5394cfe 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.3E-50 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS26430 ee40247c5a93c64d0d733becae1ebc58 414 Gene3D G3DSA:3.40.640.10 1 291 2.2E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS26430 ee40247c5a93c64d0d733becae1ebc58 414 PIRSF PIRSF001434 1 411 1.5E-117 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS26430 ee40247c5a93c64d0d733becae1ebc58 414 Gene3D G3DSA:3.90.1150.10 292 414 8.7E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS26430 ee40247c5a93c64d0d733becae1ebc58 414 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 408 1.7E-103 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS26430 ee40247c5a93c64d0d733becae1ebc58 414 SUPERFAMILY SSF53383 5 409 9.14E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS06370 6671755ea41f07317a9ae3f578834fd8 362 Gene3D G3DSA:3.40.190.10 63 154 6.8E-7 T 29-03-2018 CVS48_RS06370 6671755ea41f07317a9ae3f578834fd8 362 Pfam PF09084 NMT1/THI5 like 72 273 5.6E-22 T 29-03-2018 IPR015168 SsuA/THI5-like CVS48_RS06370 6671755ea41f07317a9ae3f578834fd8 362 Gene3D G3DSA:3.40.190.10 155 288 7.1E-16 T 29-03-2018 CVS48_RS06370 6671755ea41f07317a9ae3f578834fd8 362 SUPERFAMILY SSF53850 64 280 2.06E-23 T 29-03-2018 CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 13 944 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 Pfam PF00676 Dehydrogenase E1 component 221 525 2.3E-48 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 10 48 1.0E-17 T 29-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 803 945 1.2E-50 T 29-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 Pfam PF02779 Transketolase, pyrimidine binding domain 601 798 9.5E-64 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 SUPERFAMILY SSF52518 126 551 1.69E-88 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 SUPERFAMILY SSF52518 585 804 5.49E-46 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 Gene3D G3DSA:3.40.50.970 600 809 2.4E-56 T 29-03-2018 CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 Gene3D G3DSA:1.10.287.1150 89 172 7.1E-24 T 29-03-2018 CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 Gene3D G3DSA:3.40.50.970 173 532 1.7E-86 T 29-03-2018 CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 PIRSF PIRSF000157 1 947 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CVS48_RS27810 1e47525907926de1f55c62007c029b1c 955 SMART SM00861 601 798 4.8E-57 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS13360 813369107e24434d0689b74dd5bf9acd 547 Gene3D G3DSA:3.10.105.10 313 512 2.5E-49 T 29-03-2018 CVS48_RS13360 813369107e24434d0689b74dd5bf9acd 547 Gene3D G3DSA:3.90.76.10 66 167 7.6E-32 T 29-03-2018 CVS48_RS13360 813369107e24434d0689b74dd5bf9acd 547 PIRSF PIRSF002741 2 547 9.9E-139 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS13360 813369107e24434d0689b74dd5bf9acd 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 93 450 4.4E-88 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS13360 813369107e24434d0689b74dd5bf9acd 547 SUPERFAMILY SSF53850 47 544 2.17E-131 T 29-03-2018 CVS48_RS13360 813369107e24434d0689b74dd5bf9acd 547 Gene3D G3DSA:3.40.190.10 168 312 2.4E-43 T 29-03-2018 CVS48_RS10425 2ed2abb306000dc51e29c67c03eb0737 239 SUPERFAMILY SSF52540 1 234 1.41E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10425 2ed2abb306000dc51e29c67c03eb0737 239 Gene3D G3DSA:3.40.50.300 1 237 6.2E-56 T 29-03-2018 CVS48_RS10425 2ed2abb306000dc51e29c67c03eb0737 239 Pfam PF00005 ABC transporter 18 164 7.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS10425 2ed2abb306000dc51e29c67c03eb0737 239 SMART SM00382 27 212 1.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 SUPERFAMILY SSF46785 4 105 1.34E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 2.9E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 SUPERFAMILY SSF53850 91 298 3.73E-26 T 29-03-2018 CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 Pfam PF03466 LysR substrate binding domain 91 298 1.1E-24 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 Gene3D G3DSA:3.40.190.10 185 269 2.7E-9 T 29-03-2018 CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 Gene3D G3DSA:3.40.190.10 92 184 6.9E-13 T 29-03-2018 CVS48_RS11665 cbf76c1f3fb8f6f9487a7e619989ca71 312 Gene3D G3DSA:1.10.10.10 1 86 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15715 b441ecfad075b3136312596313f439f2 173 Pfam PF00578 AhpC/TSA family 34 150 1.0E-15 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS15715 b441ecfad075b3136312596313f439f2 173 Gene3D G3DSA:3.40.30.10 29 173 1.3E-27 T 29-03-2018 CVS48_RS15715 b441ecfad075b3136312596313f439f2 173 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 5 170 8.8E-52 T 29-03-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 CVS48_RS15715 b441ecfad075b3136312596313f439f2 173 SUPERFAMILY SSF52833 29 170 3.31E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS15715 b441ecfad075b3136312596313f439f2 173 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 81 1.7E-34 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 SUPERFAMILY SSF54719 85 191 1.44E-43 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 2.6E-40 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 SUPERFAMILY SSF46609 1 83 4.98E-36 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 PIRSF PIRSF000349 1 192 7.1E-87 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 Gene3D G3DSA:1.10.287.990 20 82 5.4E-27 T 29-03-2018 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 1.1E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 1.1E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.1E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.1E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 1.1E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS22445 e04b3ab78e257ebcede03abfbb5f4620 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS12220 cbbdffdd7d5e5174ad61ed19fe2cabec 333 Pfam PF16220 Domain of unknown function (DUF4880) 18 58 1.1E-9 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS12220 cbbdffdd7d5e5174ad61ed19fe2cabec 333 Pfam PF04773 FecR protein 120 218 3.9E-18 T 29-03-2018 IPR006860 FecR protein CVS48_RS12220 cbbdffdd7d5e5174ad61ed19fe2cabec 333 PIRSF PIRSF018266 7 332 1.5E-86 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS04475 79a05fc24f3d17e0873d9a5969bb7763 197 Gene3D G3DSA:2.60.120.10 113 193 2.6E-26 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS04475 79a05fc24f3d17e0873d9a5969bb7763 197 Gene3D G3DSA:2.60.120.10 11 112 3.1E-41 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS04475 79a05fc24f3d17e0873d9a5969bb7763 197 Pfam PF05962 HutD 12 174 3.3E-53 T 29-03-2018 IPR010282 Uncharacterised protein family HutD/Ves CVS48_RS04475 79a05fc24f3d17e0873d9a5969bb7763 197 SUPERFAMILY SSF51182 5 182 4.0E-54 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS20195 72bfa4efb6f6960cae9a9e7b3f699b18 234 SUPERFAMILY SSF53474 16 209 2.42E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS20195 72bfa4efb6f6960cae9a9e7b3f699b18 234 Pfam PF02230 Phospholipase/Carboxylesterase 15 210 1.2E-28 T 29-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CVS48_RS20195 72bfa4efb6f6960cae9a9e7b3f699b18 234 Gene3D G3DSA:3.40.50.1820 5 219 2.7E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 Gene3D G3DSA:1.10.1660.10 1 56 1.3E-23 T 29-03-2018 CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 Gene3D G3DSA:1.10.1660.10 57 130 6.6E-20 T 29-03-2018 CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.1E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.1E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.1E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 8.9E-56 T 29-03-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 SUPERFAMILY SSF46955 1 126 1.43E-39 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 Pfam PF09278 MerR, DNA binding 44 108 6.7E-18 T 29-03-2018 IPR015358 Transcription regulator MerR, DNA binding CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 SMART SM00422 1 70 1.8E-33 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS19770 b698ce4acd7e5de04601a97bcbc696a9 130 Pfam PF00376 MerR family regulatory protein 2 39 1.3E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS21915 a0b7df139c768decb9ed894c3511118b 170 Gene3D G3DSA:1.10.287.110 2 88 5.4E-9 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS21915 a0b7df139c768decb9ed894c3511118b 170 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 4 169 21.232 T 29-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS21915 a0b7df139c768decb9ed894c3511118b 170 Pfam PF07743 HSCB C-terminal oligomerisation domain 90 163 7.3E-15 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS21915 a0b7df139c768decb9ed894c3511118b 170 SMART SM00271 4 69 1.7E-5 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS21915 a0b7df139c768decb9ed894c3511118b 170 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 16 167 1.6E-28 T 29-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS21915 a0b7df139c768decb9ed894c3511118b 170 SUPERFAMILY SSF47144 80 166 1.12E-18 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS21915 a0b7df139c768decb9ed894c3511118b 170 Gene3D G3DSA:1.20.1280.20 89 169 2.3E-19 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS21915 a0b7df139c768decb9ed894c3511118b 170 SUPERFAMILY SSF46565 5 75 1.31E-16 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS25680 9249283db4007ad8e348c7fb5711c91f 579 Gene3D G3DSA:3.30.420.40 1 172 1.3E-27 T 29-03-2018 CVS48_RS25680 9249283db4007ad8e348c7fb5711c91f 579 SUPERFAMILY SSF53067 1 88 3.37E-17 T 29-03-2018 CVS48_RS25680 9249283db4007ad8e348c7fb5711c91f 579 SUPERFAMILY SSF53067 152 358 3.37E-17 T 29-03-2018 CVS48_RS25680 9249283db4007ad8e348c7fb5711c91f 579 Pfam PF16861 Carbamoyltransferase C-terminus 405 577 3.0E-71 T 29-03-2018 IPR031730 Carbamoyltransferase, C-terminal CVS48_RS25680 9249283db4007ad8e348c7fb5711c91f 579 Pfam PF02543 Carbamoyltransferase N-terminus 4 354 1.7E-66 T 29-03-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 Gene3D G3DSA:1.10.10.10 4 83 9.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 SMART SM00345 22 81 9.6E-25 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 Pfam PF07729 FCD domain 106 231 2.2E-23 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 4.7E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 4.7E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 SUPERFAMILY SSF46785 14 85 6.68E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 Gene3D G3DSA:1.20.120.530 84 246 1.3E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 SMART SM00895 105 232 2.2E-21 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 81 2.6E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS09325 f9c280657b1a8fcda2c0a88101fe5c95 248 SUPERFAMILY SSF48008 101 237 2.88E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS02780 b884912602826490583f1ac9b03b0af7 269 Pfam PF04794 YdjC-like protein 4 257 3.1E-45 T 29-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like CVS48_RS02780 b884912602826490583f1ac9b03b0af7 269 SUPERFAMILY SSF88713 1 264 6.45E-55 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CVS48_RS02780 b884912602826490583f1ac9b03b0af7 269 Gene3D G3DSA:3.20.20.370 1 267 1.2E-57 T 29-03-2018 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 SUPERFAMILY SSF51730 255 605 1.18E-119 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 Gene3D G3DSA:3.40.309.10 898 1081 8.8E-46 T 29-03-2018 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 SUPERFAMILY SSF81935 87 253 1.96E-62 T 29-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 906 917 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 SUPERFAMILY SSF53720 634 1104 1.7E-128 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 Gene3D G3DSA:3.20.20.220 170 596 2.0E-104 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 141 252 6.1E-47 T 29-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 Gene3D G3DSA:1.20.5.550 88 134 1.0E-16 T 29-03-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 Pfam PF01619 Proline dehydrogenase 264 561 1.0E-97 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 SUPERFAMILY SSF47598 4 45 1.47E-7 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 607 1103 2.0E-231 T 29-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 PIRSF PIRSF000197 73 1273 0.0 T 29-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 Gene3D G3DSA:3.40.605.10 639 897 2.1E-74 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 Gene3D G3DSA:1.10.1220.10 2 48 3.4E-4 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CVS48_RS22380 c8600f5b57050805675111e71e863570 1273 Pfam PF00171 Aldehyde dehydrogenase family 655 1097 1.7E-118 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS23260 66657242bb6fad87efebbc49bb32eebe 246 SUPERFAMILY SSF63892 1 238 7.98E-93 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CVS48_RS23260 66657242bb6fad87efebbc49bb32eebe 246 Gene3D G3DSA:3.20.20.70 2 235 1.4E-97 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS23260 66657242bb6fad87efebbc49bb32eebe 246 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 235 3.4E-88 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CVS48_RS23260 66657242bb6fad87efebbc49bb32eebe 246 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 240 122.296 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CVS48_RS23260 66657242bb6fad87efebbc49bb32eebe 246 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 3 235 8.2E-97 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CVS48_RS19005 d08b9e8840df69c523e9f077d4d16f05 318 Gene3D G3DSA:3.40.50.720 4 114 8.9E-31 T 29-03-2018 CVS48_RS19005 d08b9e8840df69c523e9f077d4d16f05 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 279 3.6E-50 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS19005 d08b9e8840df69c523e9f077d4d16f05 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 310 1.2E-23 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CVS48_RS19005 d08b9e8840df69c523e9f077d4d16f05 318 Gene3D G3DSA:3.40.50.720 115 282 1.8E-53 T 29-03-2018 CVS48_RS19005 d08b9e8840df69c523e9f077d4d16f05 318 SUPERFAMILY SSF52283 6 133 2.08E-33 T 29-03-2018 CVS48_RS19005 d08b9e8840df69c523e9f077d4d16f05 318 SUPERFAMILY SSF51735 100 280 9.34E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25060 c7de35beeb2e389cfef84d4629032683 527 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 322 333 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS25060 c7de35beeb2e389cfef84d4629032683 527 Gene3D G3DSA:3.40.309.10 311 504 3.6E-71 T 29-03-2018 CVS48_RS25060 c7de35beeb2e389cfef84d4629032683 527 SUPERFAMILY SSF53720 49 522 2.09E-156 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS25060 c7de35beeb2e389cfef84d4629032683 527 Pfam PF00171 Aldehyde dehydrogenase family 67 519 6.4E-163 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS25060 c7de35beeb2e389cfef84d4629032683 527 Gene3D G3DSA:3.40.605.10 43 310 8.8E-86 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS25060 c7de35beeb2e389cfef84d4629032683 527 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 294 301 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS17675 402800f7f7f949923fa94ac8afaf0106 389 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 56 384 4.9E-70 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS17675 402800f7f7f949923fa94ac8afaf0106 389 Gene3D G3DSA:2.40.50.100 185 363 0.0021 T 29-03-2018 CVS48_RS17675 402800f7f7f949923fa94ac8afaf0106 389 SUPERFAMILY SSF111369 72 307 4.58E-50 T 29-03-2018 CVS48_RS17675 402800f7f7f949923fa94ac8afaf0106 389 Gene3D G3DSA:2.40.50.100 80 153 1.1E-16 T 29-03-2018 CVS48_RS17675 402800f7f7f949923fa94ac8afaf0106 389 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 303 6.5E-12 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS07425 0543e3989effb2d1ab68a0466a9cc2a1 332 PIRSF PIRSF017082 4 332 1.8E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS07425 0543e3989effb2d1ab68a0466a9cc2a1 332 Gene3D G3DSA:3.40.190.10 41 299 2.1E-10 T 29-03-2018 CVS48_RS07425 0543e3989effb2d1ab68a0466a9cc2a1 332 SUPERFAMILY SSF53850 119 291 9.06E-12 T 29-03-2018 CVS48_RS07425 0543e3989effb2d1ab68a0466a9cc2a1 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 328 3.3E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13330 2e530662ca4126f9aea4709bf3bfe4b3 249 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 7 228 2.1E-97 T 29-03-2018 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS13330 2e530662ca4126f9aea4709bf3bfe4b3 249 SMART SM00382 39 232 4.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13330 2e530662ca4126f9aea4709bf3bfe4b3 249 Pfam PF00005 ABC transporter 30 184 9.7E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13330 2e530662ca4126f9aea4709bf3bfe4b3 249 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13330 2e530662ca4126f9aea4709bf3bfe4b3 249 Gene3D G3DSA:3.40.50.300 4 240 4.2E-45 T 29-03-2018 CVS48_RS13330 2e530662ca4126f9aea4709bf3bfe4b3 249 SUPERFAMILY SSF52540 6 229 1.36E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19000 9d738e69cee1d9d2c8a5018d63a98b56 278 SUPERFAMILY SSF52402 154 275 1.0E-18 T 29-03-2018 CVS48_RS19000 9d738e69cee1d9d2c8a5018d63a98b56 278 Pfam PF00582 Universal stress protein family 154 275 6.5E-9 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS19000 9d738e69cee1d9d2c8a5018d63a98b56 278 Pfam PF00582 Universal stress protein family 1 143 8.5E-9 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS19000 9d738e69cee1d9d2c8a5018d63a98b56 278 Gene3D G3DSA:3.40.50.620 148 277 2.3E-18 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS19000 9d738e69cee1d9d2c8a5018d63a98b56 278 PRINTS PR01438 Universal stress protein signature 238 250 1.2E-6 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS19000 9d738e69cee1d9d2c8a5018d63a98b56 278 PRINTS PR01438 Universal stress protein signature 152 170 1.2E-6 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS19000 9d738e69cee1d9d2c8a5018d63a98b56 278 PRINTS PR01438 Universal stress protein signature 256 278 1.2E-6 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS19000 9d738e69cee1d9d2c8a5018d63a98b56 278 Gene3D G3DSA:3.40.50.620 1 147 2.1E-13 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS19000 9d738e69cee1d9d2c8a5018d63a98b56 278 SUPERFAMILY SSF52402 1 143 4.6E-14 T 29-03-2018 CVS48_RS03305 58c595961cbd352aebe049b24f5c6cd5 246 SUPERFAMILY SSF69593 7 176 6.15E-29 T 29-03-2018 CVS48_RS03305 58c595961cbd352aebe049b24f5c6cd5 246 SMART SM00563 67 179 8.0E-34 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CVS48_RS03305 58c595961cbd352aebe049b24f5c6cd5 246 Pfam PF01553 Acyltransferase 64 176 1.2E-20 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CVS48_RS03305 58c595961cbd352aebe049b24f5c6cd5 246 Gene3D G3DSA:3.40.1130.10 30 238 1.9E-30 T 29-03-2018 CVS48_RS04455 fb26c5764c6842daa911cedb9c8cbf95 468 Pfam PF00324 Amino acid permease 16 446 5.4E-107 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CVS48_RS04455 fb26c5764c6842daa911cedb9c8cbf95 468 PIRSF PIRSF006060 1 453 6.6E-69 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CVS48_RS04455 fb26c5764c6842daa911cedb9c8cbf95 468 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 3.1E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 3.1E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 Pfam PF07702 UTRA domain 97 233 5.2E-39 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 SUPERFAMILY SSF46785 9 79 1.08E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 SMART SM00866 96 233 2.4E-39 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 2.9E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 11 239 5.8E-105 T 29-03-2018 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 Gene3D G3DSA:3.40.1410.10 76 239 5.9E-44 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 SUPERFAMILY SSF64288 63 236 3.93E-47 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 SMART SM00345 16 75 3.2E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS04480 90eb8131105c2e2c8e1683a94fd5ea7f 240 Gene3D G3DSA:1.10.10.10 3 75 1.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07305 5decfe1c59ad9472664fefe46df87bf0 296 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 22 287 2.6E-65 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CVS48_RS07305 5decfe1c59ad9472664fefe46df87bf0 296 PIRSF PIRSF026649 1 296 2.6E-76 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CVS48_RS19010 c73b302600f5d1a05cea67c6430c5631 50 Pfam PF11752 Protein of unknown function (DUF3309) 2 50 1.5E-24 T 29-03-2018 IPR021738 Protein of unknown function DUF3309 CVS48_RS06470 79166070bba81203515b3e2a65c5ca94 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 8.5E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS06470 79166070bba81203515b3e2a65c5ca94 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 8.5E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS06470 79166070bba81203515b3e2a65c5ca94 293 SUPERFAMILY SSF53474 6 279 9.55E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS06470 79166070bba81203515b3e2a65c5ca94 293 Gene3D G3DSA:3.40.50.1820 9 282 4.8E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS06470 79166070bba81203515b3e2a65c5ca94 293 Pfam PF00561 alpha/beta hydrolase fold 30 265 4.4E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS13110 b41ced387f01662de78c057ad3620891 386 Pfam PF01734 Patatin-like phospholipase 1 223 9.4E-21 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CVS48_RS13110 b41ced387f01662de78c057ad3620891 386 Gene3D G3DSA:3.40.1090.10 1 338 1.9E-40 T 29-03-2018 CVS48_RS13110 b41ced387f01662de78c057ad3620891 386 SUPERFAMILY SSF52151 1 272 2.62E-46 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CVS48_RS24130 48434ca59b7157fe9dde0b1acb0cd3fd 308 Gene3D G3DSA:3.40.190.10 176 264 3.1E-16 T 29-03-2018 CVS48_RS24130 48434ca59b7157fe9dde0b1acb0cd3fd 308 Pfam PF03466 LysR substrate binding domain 86 287 2.1E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS24130 48434ca59b7157fe9dde0b1acb0cd3fd 308 SUPERFAMILY SSF53850 87 295 4.95E-33 T 29-03-2018 CVS48_RS24130 48434ca59b7157fe9dde0b1acb0cd3fd 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.2E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS24130 48434ca59b7157fe9dde0b1acb0cd3fd 308 Gene3D G3DSA:3.40.190.10 89 175 1.8E-14 T 29-03-2018 CVS48_RS24130 48434ca59b7157fe9dde0b1acb0cd3fd 308 Gene3D G3DSA:1.10.10.10 1 82 4.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24130 48434ca59b7157fe9dde0b1acb0cd3fd 308 SUPERFAMILY SSF46785 1 84 1.14E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23315 772da5b90203ff04bf9ac55bc237717f 116 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 7 116 1.3E-36 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CVS48_RS23315 772da5b90203ff04bf9ac55bc237717f 116 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 116 24.393 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CVS48_RS23315 772da5b90203ff04bf9ac55bc237717f 116 Gene3D G3DSA:3.60.90.10 2 116 1.1E-38 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CVS48_RS23315 772da5b90203ff04bf9ac55bc237717f 116 SUPERFAMILY SSF56276 7 116 1.45E-32 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CVS48_RS23315 772da5b90203ff04bf9ac55bc237717f 116 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 2.1E-35 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CVS48_RS25665 d53c5d7c90fc5b681754a4c152fe45e6 323 Gene3D G3DSA:3.40.50.2000 49 303 2.3E-18 T 29-03-2018 CVS48_RS25665 d53c5d7c90fc5b681754a4c152fe45e6 323 SUPERFAMILY SSF53756 28 318 4.31E-23 T 29-03-2018 CVS48_RS25665 d53c5d7c90fc5b681754a4c152fe45e6 323 Pfam PF00534 Glycosyl transferases group 1 206 296 2.2E-11 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS07895 a64836029bc9025b45826b4ca181421a 173 SUPERFAMILY SSF55154 3 167 8.5E-34 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CVS48_RS07895 a64836029bc9025b45826b4ca181421a 173 SMART SM01118 2 169 3.6E-12 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CVS48_RS07895 a64836029bc9025b45826b4ca181421a 173 Gene3D G3DSA:2.40.320.10 1 169 3.5E-23 T 29-03-2018 CVS48_RS07895 a64836029bc9025b45826b4ca181421a 173 Pfam PF01928 CYTH domain 3 163 1.3E-17 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CVS48_RS01360 805b55dab972abedf4d07c9ccc938f2f 283 Gene3D G3DSA:3.90.550.10 1 280 1.5E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS01360 805b55dab972abedf4d07c9ccc938f2f 283 Pfam PF00483 Nucleotidyl transferase 11 272 1.4E-29 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CVS48_RS01360 805b55dab972abedf4d07c9ccc938f2f 283 SUPERFAMILY SSF53448 2 273 1.3E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS01360 805b55dab972abedf4d07c9ccc938f2f 283 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 269 1.4E-107 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CVS48_RS11920 4c4dc5306e26b002731dd2c12d87240e 291 Gene3D G3DSA:1.10.1040.10 170 282 3.0E-21 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS11920 4c4dc5306e26b002731dd2c12d87240e 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 126 7.1E-9 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CVS48_RS11920 4c4dc5306e26b002731dd2c12d87240e 291 Pfam PF09130 Domain of unknown function (DUF1932) 188 257 6.2E-7 T 29-03-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal CVS48_RS11920 4c4dc5306e26b002731dd2c12d87240e 291 SUPERFAMILY SSF51735 1 144 1.3E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11920 4c4dc5306e26b002731dd2c12d87240e 291 SUPERFAMILY SSF48179 161 258 5.78E-18 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS11920 4c4dc5306e26b002731dd2c12d87240e 291 Gene3D G3DSA:3.40.50.720 2 167 1.2E-19 T 29-03-2018 CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 Pfam PF00106 short chain dehydrogenase 4 195 4.6E-62 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.0E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.0E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.0E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 244 1.9E-117 T 29-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 SUPERFAMILY SSF51735 3 244 4.48E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 188 0.001 T 29-03-2018 CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 Gene3D G3DSA:3.40.50.720 47 245 1.9E-62 T 29-03-2018 CVS48_RS27675 dc8ae3d69f2ec50c21811f4f840f92b1 245 Gene3D G3DSA:3.40.50.720 1 46 7.5E-7 T 29-03-2018 CVS48_RS24490 e3994096643661ec47a4466f6d860236 396 Gene3D G3DSA:1.10.443.10 207 380 2.1E-23 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS24490 e3994096643661ec47a4466f6d860236 396 Gene3D G3DSA:1.10.150.130 86 206 1.0E-16 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CVS48_RS24490 e3994096643661ec47a4466f6d860236 396 Pfam PF13356 Arm DNA-binding domain 3 86 3.2E-19 T 29-03-2018 IPR025166 Integrase, DNA-binding domain CVS48_RS24490 e3994096643661ec47a4466f6d860236 396 Pfam PF00589 Phage integrase family 209 370 1.9E-19 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS24490 e3994096643661ec47a4466f6d860236 396 SUPERFAMILY SSF56349 98 380 3.83E-57 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS08520 65ce1712861b1cf9ddfcc59728ec9635 316 SUPERFAMILY SSF141571 25 188 8.63E-28 T 29-03-2018 CVS48_RS08520 65ce1712861b1cf9ddfcc59728ec9635 316 Gene3D G3DSA:2.160.20.80 172 312 8.0E-26 T 29-03-2018 CVS48_RS08520 65ce1712861b1cf9ddfcc59728ec9635 316 Pfam PF13599 Pentapeptide repeats (9 copies) 156 231 1.6E-8 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS08520 65ce1712861b1cf9ddfcc59728ec9635 316 Pfam PF13599 Pentapeptide repeats (9 copies) 28 92 2.0E-6 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS08520 65ce1712861b1cf9ddfcc59728ec9635 316 Pfam PF00805 Pentapeptide repeats (8 copies) 255 286 2.3E-5 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS08520 65ce1712861b1cf9ddfcc59728ec9635 316 Gene3D G3DSA:2.160.10.20 99 171 4.6E-12 T 29-03-2018 CVS48_RS08520 65ce1712861b1cf9ddfcc59728ec9635 316 SUPERFAMILY SSF141571 142 306 1.1E-33 T 29-03-2018 CVS48_RS08520 65ce1712861b1cf9ddfcc59728ec9635 316 Gene3D G3DSA:2.160.10.20 20 98 2.7E-11 T 29-03-2018 CVS48_RS12870 0ccd327b2bcdd3575775f9fdf71db218 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 6 162 31.724 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CVS48_RS12870 0ccd327b2bcdd3575775f9fdf71db218 162 Pfam PF01967 MoaC family 19 154 2.3E-46 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CVS48_RS12870 0ccd327b2bcdd3575775f9fdf71db218 162 SUPERFAMILY SSF55040 15 159 1.83E-53 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CVS48_RS12870 0ccd327b2bcdd3575775f9fdf71db218 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 8 156 8.8E-53 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CVS48_RS12870 0ccd327b2bcdd3575775f9fdf71db218 162 Gene3D G3DSA:3.30.70.640 6 162 7.2E-61 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 SUPERFAMILY SSF64288 71 246 5.81E-38 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 SUPERFAMILY SSF46785 12 95 1.02E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 4.3E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 SMART SM00866 105 242 5.4E-31 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 Gene3D G3DSA:3.40.1410.10 84 249 1.8E-35 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 Gene3D G3DSA:1.10.10.10 10 83 4.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 Pfam PF07702 UTRA domain 106 240 1.6E-32 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 SMART SM00345 24 83 1.5E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 1.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS23920 315c48d172ece4ee027e14b340ac9276 299 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 1.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11395 11ab7d1ba44f2c63b1f5da9ae5c639c1 272 Pfam PF09339 IclR helix-turn-helix domain 30 79 1.7E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS11395 11ab7d1ba44f2c63b1f5da9ae5c639c1 272 SMART SM00346 28 118 6.5E-18 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS11395 11ab7d1ba44f2c63b1f5da9ae5c639c1 272 Pfam PF01614 Bacterial transcriptional regulator 147 269 1.4E-15 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS11395 11ab7d1ba44f2c63b1f5da9ae5c639c1 272 SUPERFAMILY SSF46785 28 99 1.84E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11395 11ab7d1ba44f2c63b1f5da9ae5c639c1 272 SUPERFAMILY SSF55781 97 269 3.73E-33 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS11395 11ab7d1ba44f2c63b1f5da9ae5c639c1 272 Gene3D G3DSA:1.10.10.10 13 89 1.6E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11395 11ab7d1ba44f2c63b1f5da9ae5c639c1 272 Gene3D G3DSA:3.30.450.40 102 272 9.5E-36 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS17135 6f5be208f7fe6b7aa5d5d9b20a50a778 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 26.389 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CVS48_RS17135 6f5be208f7fe6b7aa5d5d9b20a50a778 186 SUPERFAMILY SSF55194 5 185 1.83E-67 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CVS48_RS17135 6f5be208f7fe6b7aa5d5d9b20a50a778 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 186 1.3E-65 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CVS48_RS17135 6f5be208f7fe6b7aa5d5d9b20a50a778 186 Gene3D G3DSA:1.10.132.20 4 75 5.0E-8 T 29-03-2018 CVS48_RS17135 6f5be208f7fe6b7aa5d5d9b20a50a778 186 Gene3D G3DSA:1.10.132.20 76 185 4.3E-36 T 29-03-2018 CVS48_RS17135 6f5be208f7fe6b7aa5d5d9b20a50a778 186 Pfam PF01765 Ribosome recycling factor 21 184 1.2E-60 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CVS48_RS01660 d162549fc732ef1c58165ffd5ea7ae89 378 Pfam PF00425 chorismate binding enzyme 119 372 1.2E-86 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CVS48_RS01660 d162549fc732ef1c58165ffd5ea7ae89 378 Gene3D G3DSA:3.60.120.10 26 378 4.0E-113 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CVS48_RS01660 d162549fc732ef1c58165ffd5ea7ae89 378 PRINTS PR00095 Anthranilate synthase component I signature 328 342 7.4E-15 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS01660 d162549fc732ef1c58165ffd5ea7ae89 378 PRINTS PR00095 Anthranilate synthase component I signature 313 327 7.4E-15 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS01660 d162549fc732ef1c58165ffd5ea7ae89 378 PRINTS PR00095 Anthranilate synthase component I signature 220 233 7.4E-15 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS01660 d162549fc732ef1c58165ffd5ea7ae89 378 PRINTS PR00095 Anthranilate synthase component I signature 234 247 7.4E-15 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS01660 d162549fc732ef1c58165ffd5ea7ae89 378 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 52 376 1.6E-109 T 29-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 CVS48_RS01660 d162549fc732ef1c58165ffd5ea7ae89 378 SUPERFAMILY SSF56322 29 377 3.53E-106 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CVS48_RS27890 acdda94a6fcfa70da51553f3b05f02ff 86 SUPERFAMILY SSF109910 3 79 1.96E-18 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase CVS48_RS27890 acdda94a6fcfa70da51553f3b05f02ff 86 Pfam PF03937 Flavinator of succinate dehydrogenase 9 72 5.7E-19 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase CVS48_RS27890 acdda94a6fcfa70da51553f3b05f02ff 86 Gene3D G3DSA:1.10.150.250 3 85 9.3E-20 T 29-03-2018 CVS48_RS08040 4c671a6cb241e0d2d49ca5c48ad7f97d 239 Gene3D G3DSA:1.10.10.10 2 73 5.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08040 4c671a6cb241e0d2d49ca5c48ad7f97d 239 SMART SM00895 95 221 1.1E-22 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS08040 4c671a6cb241e0d2d49ca5c48ad7f97d 239 Pfam PF07729 FCD domain 96 220 2.6E-22 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS08040 4c671a6cb241e0d2d49ca5c48ad7f97d 239 Gene3D G3DSA:1.20.120.530 81 228 2.5E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS08040 4c671a6cb241e0d2d49ca5c48ad7f97d 239 SMART SM00345 12 71 6.8E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08040 4c671a6cb241e0d2d49ca5c48ad7f97d 239 SUPERFAMILY SSF46785 4 75 3.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08040 4c671a6cb241e0d2d49ca5c48ad7f97d 239 SUPERFAMILY SSF48008 94 226 1.7E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS08040 4c671a6cb241e0d2d49ca5c48ad7f97d 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 5.6E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS09960 fbec3a2ea4f1bd414bb6d7cefdb7c5c3 398 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 394 45.618 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS09960 fbec3a2ea4f1bd414bb6d7cefdb7c5c3 398 PIRSF PIRSF001413 7 397 4.2E-138 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS09960 fbec3a2ea4f1bd414bb6d7cefdb7c5c3 398 Gene3D G3DSA:3.40.50.1100 202 395 2.3E-33 T 29-03-2018 CVS48_RS09960 fbec3a2ea4f1bd414bb6d7cefdb7c5c3 398 SUPERFAMILY SSF53686 14 392 7.2E-124 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS09960 fbec3a2ea4f1bd414bb6d7cefdb7c5c3 398 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 84 98 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS09960 fbec3a2ea4f1bd414bb6d7cefdb7c5c3 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 381 1.9E-43 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS09960 fbec3a2ea4f1bd414bb6d7cefdb7c5c3 398 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 14 389 2.5E-162 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS09960 fbec3a2ea4f1bd414bb6d7cefdb7c5c3 398 Gene3D G3DSA:3.40.50.1100 13 201 7.8E-36 T 29-03-2018 CVS48_RS14545 e54a4cfdcd2be4591f741b7f222b04aa 122 SUPERFAMILY SSF50692 1 119 1.62E-47 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CVS48_RS14545 e54a4cfdcd2be4591f741b7f222b04aa 122 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 122 69.458 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CVS48_RS14545 e54a4cfdcd2be4591f741b7f222b04aa 122 Gene3D G3DSA:2.40.40.20 1 117 4.6E-51 T 29-03-2018 CVS48_RS14545 e54a4cfdcd2be4591f741b7f222b04aa 122 PIRSF PIRSF006246 1 121 8.7E-51 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CVS48_RS14545 e54a4cfdcd2be4591f741b7f222b04aa 122 Pfam PF02261 Aspartate decarboxylase 1 114 1.1E-48 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CVS48_RS14545 e54a4cfdcd2be4591f741b7f222b04aa 122 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 1.0E-51 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CVS48_RS14545 e54a4cfdcd2be4591f741b7f222b04aa 122 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 4.0E-48 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CVS48_RS02045 800fb169bc415a5f3cf45d21eaf0f08e 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.7E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS02045 800fb169bc415a5f3cf45d21eaf0f08e 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.7E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS02045 800fb169bc415a5f3cf45d21eaf0f08e 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.7E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS02045 800fb169bc415a5f3cf45d21eaf0f08e 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.7E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS02045 800fb169bc415a5f3cf45d21eaf0f08e 149 SMART SM00347 28 128 6.3E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS02045 800fb169bc415a5f3cf45d21eaf0f08e 149 SUPERFAMILY SSF46785 5 144 7.65E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02045 800fb169bc415a5f3cf45d21eaf0f08e 149 Gene3D G3DSA:1.10.10.10 2 149 5.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02045 800fb169bc415a5f3cf45d21eaf0f08e 149 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CVS48_RS02045 800fb169bc415a5f3cf45d21eaf0f08e 149 Pfam PF12802 MarR family 34 92 5.9E-12 T 29-03-2018 CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 22 296 2.5E-83 T 29-03-2018 IPR018683 Domain of unknown function DUF2169 CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 Gene3D G3DSA:2.160.20.80 669 753 2.4E-11 T 29-03-2018 CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 Pfam PF00805 Pentapeptide repeats (8 copies) 561 599 3.8E-11 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 Pfam PF00805 Pentapeptide repeats (8 copies) 600 632 1.8E-6 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 Pfam PF13599 Pentapeptide repeats (9 copies) 763 838 9.8E-7 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 SUPERFAMILY SSF141571 554 679 2.94E-25 T 29-03-2018 CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 Gene3D G3DSA:2.160.10.20 543 611 2.2E-17 T 29-03-2018 CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 Gene3D G3DSA:2.160.10.20 612 668 1.2E-11 T 29-03-2018 CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 Gene3D G3DSA:2.160.10.20 794 864 1.4E-10 T 29-03-2018 CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 Gene3D G3DSA:3.30.1120.50 754 793 3.8E-8 T 29-03-2018 CVS48_RS06635 59d6e16d39940d2a0f6b5a982222e40a 875 SUPERFAMILY SSF141571 737 850 2.22E-21 T 29-03-2018 CVS48_RS22675 89048a4fd75c62c6b5df36ef0e3c4d0b 492 SUPERFAMILY SSF51556 61 418 3.06E-78 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS22675 89048a4fd75c62c6b5df36ef0e3c4d0b 492 Gene3D G3DSA:3.20.20.140 74 399 2.6E-70 T 29-03-2018 CVS48_RS22675 89048a4fd75c62c6b5df36ef0e3c4d0b 492 Gene3D G3DSA:2.30.40.10 400 464 5.6E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS22675 89048a4fd75c62c6b5df36ef0e3c4d0b 492 Pfam PF07969 Amidohydrolase family 51 281 3.5E-14 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS22675 89048a4fd75c62c6b5df36ef0e3c4d0b 492 Pfam PF07969 Amidohydrolase family 360 463 4.1E-22 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS22675 89048a4fd75c62c6b5df36ef0e3c4d0b 492 Gene3D G3DSA:2.30.40.10 6 73 2.6E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS22675 89048a4fd75c62c6b5df36ef0e3c4d0b 492 SUPERFAMILY SSF51338 7 60 1.64E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS22675 89048a4fd75c62c6b5df36ef0e3c4d0b 492 SUPERFAMILY SSF51338 418 464 1.64E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS16400 4056c4d88e1f3724e6a54e0da3b78da1 327 Pfam PF00107 Zinc-binding dehydrogenase 157 260 4.4E-16 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS16400 4056c4d88e1f3724e6a54e0da3b78da1 327 Gene3D G3DSA:3.40.50.720 152 265 6.8E-15 T 29-03-2018 CVS48_RS16400 4056c4d88e1f3724e6a54e0da3b78da1 327 SUPERFAMILY SSF50129 1 144 3.35E-33 T 29-03-2018 IPR011032 GroES-like CVS48_RS16400 4056c4d88e1f3724e6a54e0da3b78da1 327 Gene3D G3DSA:3.90.180.10 1 151 1.8E-42 T 29-03-2018 CVS48_RS16400 4056c4d88e1f3724e6a54e0da3b78da1 327 SUPERFAMILY SSF51735 118 283 4.84E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS16400 4056c4d88e1f3724e6a54e0da3b78da1 327 SMART SM00829 12 325 8.3E-11 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS16400 4056c4d88e1f3724e6a54e0da3b78da1 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 1.8E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS11615 eccc01a8d37868043c4760981fdbf0ef 248 Pfam PF01614 Bacterial transcriptional regulator 169 237 1.3E-10 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS11615 eccc01a8d37868043c4760981fdbf0ef 248 Gene3D G3DSA:3.30.450.40 168 246 7.3E-14 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS11615 eccc01a8d37868043c4760981fdbf0ef 248 Gene3D G3DSA:1.10.10.10 4 81 2.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11615 eccc01a8d37868043c4760981fdbf0ef 248 Gene3D G3DSA:3.30.450.40 86 167 1.2E-19 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS11615 eccc01a8d37868043c4760981fdbf0ef 248 SUPERFAMILY SSF46785 23 92 4.42E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11615 eccc01a8d37868043c4760981fdbf0ef 248 Pfam PF09339 IclR helix-turn-helix domain 23 73 2.2E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS11615 eccc01a8d37868043c4760981fdbf0ef 248 SMART SM00346 21 110 1.6E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS11615 eccc01a8d37868043c4760981fdbf0ef 248 SUPERFAMILY SSF55781 87 239 4.19E-34 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS01875 d759111f37888d03f00fa78f731350f1 376 Gene3D G3DSA:1.10.540.10 1 118 5.8E-20 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS01875 d759111f37888d03f00fa78f731350f1 376 SUPERFAMILY SSF56645 1 217 2.62E-38 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS01875 d759111f37888d03f00fa78f731350f1 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 357 4.2E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS01875 d759111f37888d03f00fa78f731350f1 376 Gene3D G3DSA:1.20.140.10 223 354 1.1E-27 T 29-03-2018 CVS48_RS01875 d759111f37888d03f00fa78f731350f1 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 6.0E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS01875 d759111f37888d03f00fa78f731350f1 376 SUPERFAMILY SSF47203 226 366 2.42E-33 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS01875 d759111f37888d03f00fa78f731350f1 376 Gene3D G3DSA:2.40.110.10 119 220 3.9E-11 T 29-03-2018 CVS48_RS17240 fc3ca2b59b7e4f3ecd28ffe8b509fc71 393 Gene3D G3DSA:3.30.70.270 216 385 3.4E-48 T 29-03-2018 CVS48_RS17240 fc3ca2b59b7e4f3ecd28ffe8b509fc71 393 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 378 6.6E-36 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS17240 fc3ca2b59b7e4f3ecd28ffe8b509fc71 393 SMART SM00267 211 382 3.2E-40 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS17240 fc3ca2b59b7e4f3ecd28ffe8b509fc71 393 SUPERFAMILY SSF55073 227 380 6.02E-43 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS17240 fc3ca2b59b7e4f3ecd28ffe8b509fc71 393 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 380 9.1E-40 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS28045 320b4dc4d16f498d8d9a6e442ced94ee 514 Gene3D G3DSA:3.40.190.10 184 278 1.9E-26 T 29-03-2018 CVS48_RS28045 320b4dc4d16f498d8d9a6e442ced94ee 514 Gene3D G3DSA:3.10.105.10 279 485 4.2E-54 T 29-03-2018 CVS48_RS28045 320b4dc4d16f498d8d9a6e442ced94ee 514 Gene3D G3DSA:3.90.76.10 39 183 1.8E-40 T 29-03-2018 CVS48_RS28045 320b4dc4d16f498d8d9a6e442ced94ee 514 SUPERFAMILY SSF53850 32 511 1.09E-139 T 29-03-2018 CVS48_RS28045 320b4dc4d16f498d8d9a6e442ced94ee 514 PIRSF PIRSF002741 4 510 4.4E-111 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS28045 320b4dc4d16f498d8d9a6e442ced94ee 514 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 428 3.5E-96 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS02880 029693c250fd3c8c5a94332e846c8954 294 Gene3D G3DSA:3.20.20.70 154 284 6.5E-42 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS02880 029693c250fd3c8c5a94332e846c8954 294 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 28 293 1.5E-96 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CVS48_RS02880 029693c250fd3c8c5a94332e846c8954 294 SUPERFAMILY SSF51690 128 293 3.92E-56 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CVS48_RS02880 029693c250fd3c8c5a94332e846c8954 294 Gene3D G3DSA:3.90.1170.20 13 153 5.6E-39 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CVS48_RS02880 029693c250fd3c8c5a94332e846c8954 294 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 39 126 4.4E-24 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CVS48_RS02880 029693c250fd3c8c5a94332e846c8954 294 SUPERFAMILY SSF54675 14 127 1.41E-31 T 29-03-2018 CVS48_RS02880 029693c250fd3c8c5a94332e846c8954 294 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 128 293 2.0E-58 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CVS48_RS02880 029693c250fd3c8c5a94332e846c8954 294 PIRSF PIRSF006250 22 294 7.7E-92 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 SMART SM00841 128 183 1.8E-27 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 Gene3D G3DSA:2.40.50.140 64 126 3.0E-20 T 29-03-2018 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 SUPERFAMILY SSF50249 65 126 1.76E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 SUPERFAMILY SSF50249 128 184 4.97E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 SMART SM01185 67 120 2.5E-20 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 Pfam PF09285 Elongation factor P, C-terminal 128 183 3.0E-24 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.2E-16 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 Gene3D G3DSA:2.40.50.140 128 183 9.0E-25 T 29-03-2018 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 3.3E-17 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 TIGRFAM TIGR00038 efp: translation elongation factor P 3 184 3.6E-64 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 Gene3D G3DSA:2.30.30.30 2 61 1.2E-15 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 SUPERFAMILY SSF50104 1 63 8.53E-15 T 29-03-2018 IPR008991 Translation protein SH3-like domain CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 Hamap MF_00141 Elongation factor P [efp]. 1 184 46.841 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CVS48_RS23550 23191c3d6bd477d69f243b00fb687f07 185 PIRSF PIRSF005901 1 185 5.4E-57 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP CVS48_RS27380 5a952d0e3d83e5ee6c770afeac7aa265 248 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 210 1.5E-38 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CVS48_RS27380 5a952d0e3d83e5ee6c770afeac7aa265 248 PIRSF PIRSF000857 3 240 1.2E-77 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CVS48_RS27380 5a952d0e3d83e5ee6c770afeac7aa265 248 Gene3D G3DSA:3.40.50.620 3 245 1.9E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS27380 5a952d0e3d83e5ee6c770afeac7aa265 248 SUPERFAMILY SSF52402 17 198 4.83E-46 T 29-03-2018 CVS48_RS27380 5a952d0e3d83e5ee6c770afeac7aa265 248 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 41 234 4.8E-80 T 29-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 2.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 Pfam PF00106 short chain dehydrogenase 3 190 2.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 SUPERFAMILY SSF51735 3 245 5.37E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 Gene3D G3DSA:3.40.50.720 2 253 1.8E-52 T 29-03-2018 CVS48_RS13800 0b635739709957e92f6dbfd31a5c1c69 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS18825 2a4289bb675b58ef22718e589fce270d 154 SUPERFAMILY SSF46785 3 136 7.56E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18825 2a4289bb675b58ef22718e589fce270d 154 Pfam PF02082 Transcriptional regulator 1 81 2.0E-18 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CVS48_RS18825 2a4289bb675b58ef22718e589fce270d 154 Gene3D G3DSA:1.10.10.10 1 146 3.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19430 abcf03ac811198a25880d55e18d43a7e 321 Gene3D G3DSA:3.40.190.10 123 230 2.4E-13 T 29-03-2018 CVS48_RS19430 abcf03ac811198a25880d55e18d43a7e 321 SUPERFAMILY SSF53850 108 276 4.51E-14 T 29-03-2018 CVS48_RS19430 abcf03ac811198a25880d55e18d43a7e 321 PIRSF PIRSF017082 1 320 2.9E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS19430 abcf03ac811198a25880d55e18d43a7e 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 1.9E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09130 bbbbacedb1bb45a4ff62314e76f81a35 254 SUPERFAMILY SSF55781 75 246 4.58E-29 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09130 bbbbacedb1bb45a4ff62314e76f81a35 254 Gene3D G3DSA:1.10.260.40 42 93 2.5E-5 T 29-03-2018 CVS48_RS09130 bbbbacedb1bb45a4ff62314e76f81a35 254 SMART SM00346 11 100 6.4E-5 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS09130 bbbbacedb1bb45a4ff62314e76f81a35 254 Pfam PF09339 IclR helix-turn-helix domain 14 63 1.1E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS09130 bbbbacedb1bb45a4ff62314e76f81a35 254 SUPERFAMILY SSF46785 14 73 3.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09130 bbbbacedb1bb45a4ff62314e76f81a35 254 Gene3D G3DSA:3.30.450.40 94 254 1.9E-27 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09130 bbbbacedb1bb45a4ff62314e76f81a35 254 Gene3D G3DSA:1.10.10.60 2 41 2.3E-7 T 29-03-2018 CVS48_RS09130 bbbbacedb1bb45a4ff62314e76f81a35 254 Pfam PF01614 Bacterial transcriptional regulator 133 244 1.9E-12 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS13295 f627b9e0e8d0f5a8257c8cb1cd739545 397 Gene3D G3DSA:2.30.40.10 11 68 1.4E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS13295 f627b9e0e8d0f5a8257c8cb1cd739545 397 Gene3D G3DSA:3.20.20.140 69 366 9.8E-24 T 29-03-2018 CVS48_RS13295 f627b9e0e8d0f5a8257c8cb1cd739545 397 PIRSF PIRSF038971 10 382 1.9E-107 T 29-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS13295 f627b9e0e8d0f5a8257c8cb1cd739545 397 Pfam PF01979 Amidohydrolase family 269 374 2.1E-7 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS13295 f627b9e0e8d0f5a8257c8cb1cd739545 397 SUPERFAMILY SSF51338 348 382 8.31E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS13295 f627b9e0e8d0f5a8257c8cb1cd739545 397 SUPERFAMILY SSF51338 16 59 8.31E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS13295 f627b9e0e8d0f5a8257c8cb1cd739545 397 SUPERFAMILY SSF51556 59 106 1.13E-11 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS13295 f627b9e0e8d0f5a8257c8cb1cd739545 397 SUPERFAMILY SSF51556 146 348 1.13E-11 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 SUPERFAMILY SSF52540 67 287 4.09E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 SMART SM00382 89 242 2.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 PRINTS PR01874 DNA repair protein radA signature 10 34 2.3E-94 T 29-03-2018 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 PRINTS PR01874 DNA repair protein radA signature 172 196 2.3E-94 T 29-03-2018 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 PRINTS PR01874 DNA repair protein radA signature 320 343 2.3E-94 T 29-03-2018 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 PRINTS PR01874 DNA repair protein radA signature 81 109 2.3E-94 T 29-03-2018 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 PRINTS PR01874 DNA repair protein radA signature 246 272 2.3E-94 T 29-03-2018 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 PRINTS PR01874 DNA repair protein radA signature 122 139 2.3E-94 T 29-03-2018 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 PRINTS PR01874 DNA repair protein radA signature 211 239 2.3E-94 T 29-03-2018 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 Gene3D G3DSA:3.40.50.300 53 247 9.1E-23 T 29-03-2018 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 SUPERFAMILY SSF54211 301 452 8.72E-40 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 SUPERFAMILY SSF54211 253 267 8.72E-40 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 Gene3D G3DSA:3.30.230.10 248 453 7.2E-43 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 Pfam PF13481 AAA domain 82 220 2.8E-16 T 29-03-2018 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 449 1.9E-192 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CVS48_RS22570 1a7fde4c316d9777f8e1e2d5b294c332 453 Hamap MF_01498 DNA repair protein RadA [radA]. 21 453 43.426 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CVS48_RS19775 bdafe37c550df691a095c07908071912 503 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 4 437 68.73 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CVS48_RS19775 bdafe37c550df691a095c07908071912 503 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 363 397 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site CVS48_RS19775 bdafe37c550df691a095c07908071912 503 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 419 429 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CVS48_RS19775 bdafe37c550df691a095c07908071912 503 SUPERFAMILY SSF50249 5 59 2.06E-11 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS19775 bdafe37c550df691a095c07908071912 503 Gene3D G3DSA:3.40.50.150 69 435 1.2E-50 T 29-03-2018 CVS48_RS19775 bdafe37c550df691a095c07908071912 503 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 261 321 4.2E-7 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CVS48_RS19775 bdafe37c550df691a095c07908071912 503 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 357 431 9.6E-7 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CVS48_RS19775 bdafe37c550df691a095c07908071912 503 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 10 429 1.9E-88 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CVS48_RS19775 bdafe37c550df691a095c07908071912 503 Gene3D G3DSA:2.40.50.140 4 68 1.0E-21 T 29-03-2018 CVS48_RS19775 bdafe37c550df691a095c07908071912 503 SUPERFAMILY SSF53335 62 435 5.4E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS08925 3db4e41458a287b4c5af7753111ffadd 398 SUPERFAMILY SSF53822 29 393 1.35E-79 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS08925 3db4e41458a287b4c5af7753111ffadd 398 Gene3D G3DSA:3.40.50.2300 250 372 5.0E-8 T 29-03-2018 CVS48_RS08925 3db4e41458a287b4c5af7753111ffadd 398 Gene3D G3DSA:3.40.50.2300 22 249 2.8E-44 T 29-03-2018 CVS48_RS08925 3db4e41458a287b4c5af7753111ffadd 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 68 1.5E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS08925 3db4e41458a287b4c5af7753111ffadd 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 71 89 1.5E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS08925 3db4e41458a287b4c5af7753111ffadd 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 287 300 1.5E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS08925 3db4e41458a287b4c5af7753111ffadd 398 Pfam PF13458 Periplasmic binding protein 29 379 1.8E-68 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS06360 b02b1d4e61e6c3fd59d58dea3d4a51d3 408 Gene3D G3DSA:2.40.160.10 89 408 1.0E-61 T 29-03-2018 CVS48_RS06360 b02b1d4e61e6c3fd59d58dea3d4a51d3 408 SUPERFAMILY SSF56935 88 408 5.8E-64 T 29-03-2018 CVS48_RS06360 b02b1d4e61e6c3fd59d58dea3d4a51d3 408 Pfam PF13609 Gram-negative porin 70 388 1.6E-54 T 29-03-2018 CVS48_RS08935 3007ef61be1e159624670401aaae6316 489 Pfam PF00171 Aldehyde dehydrogenase family 19 478 2.2E-162 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS08935 3007ef61be1e159624670401aaae6316 489 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 30 476 7.4E-196 T 29-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 CVS48_RS08935 3007ef61be1e159624670401aaae6316 489 Gene3D G3DSA:3.40.605.10 5 272 1.3E-101 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS08935 3007ef61be1e159624670401aaae6316 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS08935 3007ef61be1e159624670401aaae6316 489 Gene3D G3DSA:3.40.309.10 273 464 1.9E-66 T 29-03-2018 CVS48_RS08935 3007ef61be1e159624670401aaae6316 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS08935 3007ef61be1e159624670401aaae6316 489 SUPERFAMILY SSF53720 5 480 7.2E-165 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS20160 6e3b3d775cb38a1e8f83c87ad2fc4ae9 292 Pfam PF13437 HlyD family secretion protein 160 241 2.5E-8 T 29-03-2018 CVS48_RS20160 6e3b3d775cb38a1e8f83c87ad2fc4ae9 292 Pfam PF13533 Biotin-lipoyl like 51 98 6.2E-18 T 29-03-2018 CVS48_RS20160 6e3b3d775cb38a1e8f83c87ad2fc4ae9 292 SUPERFAMILY SSF111369 44 209 5.1E-23 T 29-03-2018 CVS48_RS20160 6e3b3d775cb38a1e8f83c87ad2fc4ae9 292 Gene3D G3DSA:2.40.50.100 121 158 0.15 T 29-03-2018 CVS48_RS20160 6e3b3d775cb38a1e8f83c87ad2fc4ae9 292 Gene3D G3DSA:2.40.50.100 51 120 1.9E-15 T 29-03-2018 CVS48_RS20160 6e3b3d775cb38a1e8f83c87ad2fc4ae9 292 Gene3D G3DSA:2.40.50.100 159 288 0.04 T 29-03-2018 CVS48_RS20160 6e3b3d775cb38a1e8f83c87ad2fc4ae9 292 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 236 2.7E-30 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS20660 9cbe43edd048b2c028fd2f08085b00a5 427 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 233 247 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS20660 9cbe43edd048b2c028fd2f08085b00a5 427 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 20 424 2.6E-100 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS20660 9cbe43edd048b2c028fd2f08085b00a5 427 SUPERFAMILY SSF53383 70 425 3.75E-88 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS20660 9cbe43edd048b2c028fd2f08085b00a5 427 Gene3D G3DSA:3.40.640.10 15 289 2.8E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS20660 9cbe43edd048b2c028fd2f08085b00a5 427 Gene3D G3DSA:3.90.1150.10 292 426 8.5E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS20660 9cbe43edd048b2c028fd2f08085b00a5 427 PIRSF PIRSF001434 4 427 1.8E-124 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS10075 d2350d5bc9ee16d861dd6f5ce96f97c7 258 Gene3D G3DSA:3.30.450.20 159 224 2.2E-4 T 29-03-2018 CVS48_RS10075 d2350d5bc9ee16d861dd6f5ce96f97c7 258 Gene3D G3DSA:3.30.450.20 51 158 7.7E-9 T 29-03-2018 CVS48_RS15745 090a20dde3c1ad3631b4e102e59f6e16 229 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS15745 090a20dde3c1ad3631b4e102e59f6e16 229 Gene3D G3DSA:3.40.50.300 21 221 2.6E-35 T 29-03-2018 CVS48_RS15745 090a20dde3c1ad3631b4e102e59f6e16 229 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 11 206 2.6E-51 T 29-03-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 CVS48_RS15745 090a20dde3c1ad3631b4e102e59f6e16 229 SMART SM00382 37 215 1.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS15745 090a20dde3c1ad3631b4e102e59f6e16 229 SUPERFAMILY SSF52540 28 205 4.1E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS15745 090a20dde3c1ad3631b4e102e59f6e16 229 Pfam PF00005 ABC transporter 30 169 1.6E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS06545 a09def9db816f8581901a480ad8951b8 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 7.8E-27 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CVS48_RS06545 a09def9db816f8581901a480ad8951b8 72 SUPERFAMILY SSF50249 1 70 6.0E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS06545 a09def9db816f8581901a480ad8951b8 72 Gene3D G3DSA:2.40.50.140 1 72 7.4E-35 T 29-03-2018 CVS48_RS06545 a09def9db816f8581901a480ad8951b8 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 8.8E-37 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CVS48_RS06545 a09def9db816f8581901a480ad8951b8 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.082 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CVS48_RS26200 2890a0381d95e6b96555022c5c8b8abe 240 SUPERFAMILY SSF109755 7 226 3.35E-67 T 29-03-2018 CVS48_RS26200 2890a0381d95e6b96555022c5c8b8abe 240 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 217 1.3E-65 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CVS48_RS26200 2890a0381d95e6b96555022c5c8b8abe 240 Gene3D G3DSA:1.20.58.220 1 116 6.0E-27 T 29-03-2018 CVS48_RS26200 2890a0381d95e6b96555022c5c8b8abe 240 Pfam PF01895 PhoU domain 21 106 1.6E-19 T 29-03-2018 IPR026022 PhoU domain CVS48_RS26200 2890a0381d95e6b96555022c5c8b8abe 240 Pfam PF01895 PhoU domain 124 209 3.2E-17 T 29-03-2018 IPR026022 PhoU domain CVS48_RS26200 2890a0381d95e6b96555022c5c8b8abe 240 PIRSF PIRSF003107 2 223 2.0E-64 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CVS48_RS26200 2890a0381d95e6b96555022c5c8b8abe 240 Gene3D G3DSA:1.20.58.220 118 239 1.7E-29 T 29-03-2018 CVS48_RS27585 e3a233942813e91cc6939888a5560c0c 137 Pfam PF06078 Bacterial protein of unknown function (DUF937) 2 110 5.9E-11 T 29-03-2018 IPR009282 Protein of unknown function DUF937 CVS48_RS27585 e3a233942813e91cc6939888a5560c0c 137 Gene3D G3DSA:1.10.10.690 1 134 1.4E-36 T 29-03-2018 CVS48_RS27585 e3a233942813e91cc6939888a5560c0c 137 SUPERFAMILY SSF140804 11 128 4.84E-31 T 29-03-2018 IPR027405 YidB-like CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 311 353 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 Gene3D G3DSA:3.40.50.880 45 274 2.8E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 Gene3D G3DSA:1.10.10.60 315 361 1.1E-10 T 29-03-2018 CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 SUPERFAMILY SSF46689 260 307 1.43E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 Pfam PF01965 DJ-1/PfpI family 70 217 1.0E-9 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 SMART SM00342 274 357 1.5E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 Pfam PF12833 Helix-turn-helix domain 280 356 7.3E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 SUPERFAMILY SSF46689 310 358 4.26E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 Gene3D G3DSA:1.10.10.60 275 314 1.7E-9 T 29-03-2018 CVS48_RS01130 f3fc38446f40f54262ff46000f504e3d 362 SUPERFAMILY SSF52317 49 239 7.41E-38 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS27430 90d12caaef57f30b359389fbb2da61f6 309 PIRSF PIRSF000089 1 309 1.0E-109 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CVS48_RS27430 90d12caaef57f30b359389fbb2da61f6 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 3.3E-36 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CVS48_RS27430 90d12caaef57f30b359389fbb2da61f6 309 Gene3D G3DSA:3.40.50.620 1 183 2.2E-44 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS27430 90d12caaef57f30b359389fbb2da61f6 309 SUPERFAMILY SSF52467 187 309 1.64E-48 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS27430 90d12caaef57f30b359389fbb2da61f6 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CVS48_RS27430 90d12caaef57f30b359389fbb2da61f6 309 Gene3D G3DSA:3.40.50.1220 185 309 4.0E-60 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS27430 90d12caaef57f30b359389fbb2da61f6 309 SUPERFAMILY SSF52402 3 186 1.6E-57 T 29-03-2018 CVS48_RS27430 90d12caaef57f30b359389fbb2da61f6 309 SMART SM00893 3 182 3.3E-57 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS27430 90d12caaef57f30b359389fbb2da61f6 309 Pfam PF01012 Electron transfer flavoprotein domain 3 169 1.6E-40 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS29060 f3addbfcc032f3225cfcb0062ccf20f5 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 31 86 7.9E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS29060 f3addbfcc032f3225cfcb0062ccf20f5 318 SUPERFAMILY SSF53850 113 312 9.15E-37 T 29-03-2018 CVS48_RS29060 f3addbfcc032f3225cfcb0062ccf20f5 318 Pfam PF03466 LysR substrate binding domain 112 312 2.1E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS29060 f3addbfcc032f3225cfcb0062ccf20f5 318 Gene3D G3DSA:3.40.190.10 201 290 3.0E-17 T 29-03-2018 CVS48_RS29060 f3addbfcc032f3225cfcb0062ccf20f5 318 SUPERFAMILY SSF46785 27 135 3.43E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS29060 f3addbfcc032f3225cfcb0062ccf20f5 318 Gene3D G3DSA:1.10.10.10 21 108 5.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS29060 f3addbfcc032f3225cfcb0062ccf20f5 318 Gene3D G3DSA:3.40.190.10 113 200 1.1E-18 T 29-03-2018 CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 Gene3D G3DSA:1.10.10.10 2 87 1.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 Gene3D G3DSA:3.40.190.10 180 273 3.1E-19 T 29-03-2018 CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 Pfam PF03466 LysR substrate binding domain 93 298 1.2E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 SUPERFAMILY SSF46785 5 114 6.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 SUPERFAMILY SSF53850 94 302 1.93E-39 T 29-03-2018 CVS48_RS16205 f0cd49d3f103e0471e05f72a3913e035 316 Gene3D G3DSA:3.40.190.10 93 179 1.9E-19 T 29-03-2018 CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 Pfam PF01145 SPFH domain / Band 7 family 26 195 6.7E-31 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 SUPERFAMILY SSF117892 53 187 3.66E-41 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 SMART SM00244 22 180 1.2E-58 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 PRINTS PR00721 Stomatin signature 156 174 2.8E-32 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 PRINTS PR00721 Stomatin signature 77 98 2.8E-32 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 PRINTS PR00721 Stomatin signature 112 129 2.8E-32 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 PRINTS PR00721 Stomatin signature 175 196 2.8E-32 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 PRINTS PR00721 Stomatin signature 29 51 2.8E-32 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 PRINTS PR00721 Stomatin signature 132 155 2.8E-32 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS17235 e4a88bf149a48bc3b7822869bfca543a 308 Pfam PF16200 C-terminal region of band_7 246 305 3.3E-28 T 29-03-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 Gene3D G3DSA:2.60.34.10 390 531 5.2E-45 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 Pfam PF00012 Hsp70 protein 21 602 1.6E-174 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 SUPERFAMILY SSF53067 198 378 2.73E-52 T 29-03-2018 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 Gene3D G3DSA:3.30.420.40 19 204 9.7E-57 T 29-03-2018 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 Gene3D G3DSA:3.30.420.40 205 246 3.8E-17 T 29-03-2018 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 203 216 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 SUPERFAMILY SSF100934 507 618 3.14E-31 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 334 348 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 PRINTS PR00301 70kDa heat shock protein signature 331 347 5.0E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 PRINTS PR00301 70kDa heat shock protein signature 150 170 5.0E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 PRINTS PR00301 70kDa heat shock protein signature 209 219 5.0E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 PRINTS PR00301 70kDa heat shock protein signature 469 485 5.0E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 PRINTS PR00301 70kDa heat shock protein signature 362 382 5.0E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 PRINTS PR00301 70kDa heat shock protein signature 48 60 5.0E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 PRINTS PR00301 70kDa heat shock protein signature 388 407 5.0E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 PRINTS PR00301 70kDa heat shock protein signature 20 33 5.0E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 SUPERFAMILY SSF100920 387 536 2.09E-46 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 SUPERFAMILY SSF53067 19 195 6.26E-51 T 29-03-2018 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 618 1.3E-272 T 29-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 Gene3D G3DSA:3.90.640.10 247 300 3.9E-14 T 29-03-2018 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 Gene3D G3DSA:3.30.420.40 301 360 2.1E-12 T 29-03-2018 CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 Gene3D G3DSA:1.20.1270.10 532 618 4.2E-11 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CVS48_RS21910 648414446296b3147c94e10e401b50d7 620 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 619 42.183 T 29-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 SMART SM00382 303 488 2.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 SMART SM00382 38 255 3.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 SUPERFAMILY SSF52540 12 239 4.22E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 Pfam PF00005 ABC transporter 29 176 1.7E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 Pfam PF00005 ABC transporter 295 438 3.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 SUPERFAMILY SSF52540 274 498 3.47E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 Gene3D G3DSA:3.40.1710.10 594 746 1.8E-26 T 29-03-2018 CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 Gene3D G3DSA:3.40.50.300 10 267 1.4E-59 T 29-03-2018 CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 Gene3D G3DSA:3.40.50.300 276 550 6.4E-64 T 29-03-2018 CVS48_RS23940 7d07f728385a6103db70fea2cd159fd2 927 Pfam PF12698 ABC-2 family transporter protein 586 918 1.4E-37 T 29-03-2018 CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 SUPERFAMILY SSF52518 404 599 4.83E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 25 597 1.1E-215 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 SUPERFAMILY SSF52467 222 393 9.05E-57 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 Gene3D G3DSA:3.40.50.1220 220 385 3.4E-49 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 25 188 3.3E-56 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 426 574 5.8E-53 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 SUPERFAMILY SSF52518 23 189 5.89E-58 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 Gene3D G3DSA:3.40.50.970 17 217 6.4E-61 T 29-03-2018 CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 463 482 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 227 364 5.6E-42 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS05750 d2f83fb7c2c2a8a30e35ae6cadf73768 608 Gene3D G3DSA:3.40.50.970 386 590 6.7E-54 T 29-03-2018 CVS48_RS06245 73d58f54b867874897ee02aa1b1e4136 126 Gene3D G3DSA:1.20.5.1030 67 118 2.0E-19 T 29-03-2018 CVS48_RS06245 73d58f54b867874897ee02aa1b1e4136 126 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 69 119 1.9E-18 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CVS48_RS06245 73d58f54b867874897ee02aa1b1e4136 126 PRINTS PR01650 Bacterial translocase SecE signature 43 64 2.7E-8 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CVS48_RS06245 73d58f54b867874897ee02aa1b1e4136 126 PRINTS PR01650 Bacterial translocase SecE signature 64 84 2.7E-8 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CVS48_RS06245 73d58f54b867874897ee02aa1b1e4136 126 PRINTS PR01650 Bacterial translocase SecE signature 88 108 2.7E-8 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CVS48_RS06245 73d58f54b867874897ee02aa1b1e4136 126 Hamap MF_00422 Protein translocase subunit SecE [secE]. 65 121 11.293 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CVS48_RS06245 73d58f54b867874897ee02aa1b1e4136 126 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 69 118 7.3E-17 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 Pfam PF13545 Crp-like helix-turn-helix domain 162 236 8.3E-21 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 SMART SM00419 181 229 1.4E-17 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 Gene3D G3DSA:1.10.10.10 159 242 1.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 187 203 5.4E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 203 218 5.4E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 ProSitePatterns PS00042 Crp-type HTH domain signature. 189 212 - T 29-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 Gene3D G3DSA:2.60.120.10 24 158 6.8E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 SMART SM00100 24 145 1.5E-6 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 SUPERFAMILY SSF46785 161 238 8.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 SUPERFAMILY SSF51206 17 156 4.84E-24 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CVS48_RS22715 e0dc396fd6ddf96e76b265570f83de1c 242 Pfam PF00027 Cyclic nucleotide-binding domain 44 126 1.2E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS11540 50b7b9b078ae43c4fc9dcadbf581a3f4 331 PIRSF PIRSF017082 1 331 1.7E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11540 50b7b9b078ae43c4fc9dcadbf581a3f4 331 SUPERFAMILY SSF53850 117 291 1.09E-14 T 29-03-2018 CVS48_RS11540 50b7b9b078ae43c4fc9dcadbf581a3f4 331 Gene3D G3DSA:3.40.190.10 132 243 4.1E-14 T 29-03-2018 CVS48_RS11540 50b7b9b078ae43c4fc9dcadbf581a3f4 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 327 2.9E-71 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS08440 2e63f1b4765a06f31851d169b142fbe4 110 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 12 78 1.3E-9 T 29-03-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB CVS48_RS18650 7ded89e02e70db0b8fd185e95a663db7 400 Gene3D G3DSA:3.90.1150.10 303 400 9.7E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS18650 7ded89e02e70db0b8fd185e95a663db7 400 Gene3D G3DSA:3.40.640.10 55 302 1.0E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS18650 7ded89e02e70db0b8fd185e95a663db7 400 Pfam PF00266 Aminotransferase class-V 44 379 7.4E-49 T 29-03-2018 IPR000192 Aminotransferase class V domain CVS48_RS18650 7ded89e02e70db0b8fd185e95a663db7 400 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 226 246 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CVS48_RS18650 7ded89e02e70db0b8fd185e95a663db7 400 SUPERFAMILY SSF53383 28 399 2.04E-76 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS26875 7b4ea63bf2b31ff74698bad73a8ee419 473 Pfam PF00990 Diguanylate cyclase, GGDEF domain 314 469 4.3E-43 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS26875 7b4ea63bf2b31ff74698bad73a8ee419 473 Gene3D G3DSA:3.30.70.270 308 473 7.0E-49 T 29-03-2018 CVS48_RS26875 7b4ea63bf2b31ff74698bad73a8ee419 473 SUPERFAMILY SSF55073 317 471 3.92E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS26875 7b4ea63bf2b31ff74698bad73a8ee419 473 Pfam PF11563 Protoglobin 42 176 3.4E-8 T 29-03-2018 CVS48_RS26875 7b4ea63bf2b31ff74698bad73a8ee419 473 SUPERFAMILY SSF46458 46 154 6.19E-12 T 29-03-2018 IPR009050 Globin-like CVS48_RS26875 7b4ea63bf2b31ff74698bad73a8ee419 473 Gene3D G3DSA:1.10.490.10 35 178 1.1E-10 T 29-03-2018 CVS48_RS26875 7b4ea63bf2b31ff74698bad73a8ee419 473 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 311 471 4.1E-49 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS26875 7b4ea63bf2b31ff74698bad73a8ee419 473 SMART SM00267 300 473 1.4E-54 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS20450 b5ef3a47407f735bf1aca9e52350bbe1 424 Gene3D G3DSA:1.25.40.10 210 424 2.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS20450 b5ef3a47407f735bf1aca9e52350bbe1 424 Gene3D G3DSA:1.10.1740.10 1 83 6.0E-13 T 29-03-2018 CVS48_RS20450 b5ef3a47407f735bf1aca9e52350bbe1 424 Pfam PF04542 Sigma-70 region 2 25 76 5.3E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS20450 b5ef3a47407f735bf1aca9e52350bbe1 424 Pfam PF08281 Sigma-70, region 4 125 174 1.1E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS20450 b5ef3a47407f735bf1aca9e52350bbe1 424 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 174 8.2E-13 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS20450 b5ef3a47407f735bf1aca9e52350bbe1 424 Gene3D G3DSA:1.10.10.10 122 200 1.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20450 b5ef3a47407f735bf1aca9e52350bbe1 424 SUPERFAMILY SSF88659 114 175 1.07E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS20450 b5ef3a47407f735bf1aca9e52350bbe1 424 SUPERFAMILY SSF88946 6 76 1.84E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04315 f7c20c1f9653a0832ddd32fb4fee853e 210 Gene3D G3DSA:1.20.950.20 4 210 1.2E-49 T 29-03-2018 CVS48_RS04315 f7c20c1f9653a0832ddd32fb4fee853e 210 SUPERFAMILY SSF81342 6 209 2.12E-52 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CVS48_RS04315 f7c20c1f9653a0832ddd32fb4fee853e 210 Pfam PF01292 Prokaryotic cytochrome b561 12 189 4.3E-26 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CVS48_RS04315 f7c20c1f9653a0832ddd32fb4fee853e 210 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 9 210 1.1E-59 T 29-03-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 CVS48_RS10950 35830c66168754e95d10bd263bfe7114 128 Pfam PF03476 MOSC N-terminal beta barrel domain 22 110 1.9E-10 T 29-03-2018 IPR005303 MOSC, N-terminal beta barrel CVS48_RS10950 35830c66168754e95d10bd263bfe7114 128 SUPERFAMILY SSF141673 7 124 9.94E-29 T 29-03-2018 CVS48_RS05120 5df56419f14082ddd7439c90910ed846 246 SUPERFAMILY SSF51366 1 238 3.53E-75 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CVS48_RS05120 5df56419f14082ddd7439c90910ed846 246 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 240 36.199 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CVS48_RS05120 5df56419f14082ddd7439c90910ed846 246 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 236 1.5E-76 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CVS48_RS05120 5df56419f14082ddd7439c90910ed846 246 Gene3D G3DSA:3.20.20.70 2 244 4.6E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS05120 5df56419f14082ddd7439c90910ed846 246 Pfam PF00977 Histidine biosynthesis protein 3 232 7.2E-79 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CVS48_RS27875 94aa8eb18597f6a85992928e1bc6ac60 299 Gene3D G3DSA:3.40.190.10 86 171 2.5E-10 T 29-03-2018 CVS48_RS27875 94aa8eb18597f6a85992928e1bc6ac60 299 Gene3D G3DSA:3.40.190.10 172 259 3.1E-20 T 29-03-2018 CVS48_RS27875 94aa8eb18597f6a85992928e1bc6ac60 299 Gene3D G3DSA:1.10.10.10 1 78 2.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27875 94aa8eb18597f6a85992928e1bc6ac60 299 SUPERFAMILY SSF46785 1 80 1.53E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27875 94aa8eb18597f6a85992928e1bc6ac60 299 Pfam PF03466 LysR substrate binding domain 83 285 7.5E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS27875 94aa8eb18597f6a85992928e1bc6ac60 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 57 8.8E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS27875 94aa8eb18597f6a85992928e1bc6ac60 299 SUPERFAMILY SSF53850 84 289 1.74E-34 T 29-03-2018 CVS48_RS28355 85242b94d83c0ed690928c85ae8f87d8 261 Gene3D G3DSA:1.10.101.10 183 261 5.8E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like CVS48_RS28355 85242b94d83c0ed690928c85ae8f87d8 261 SUPERFAMILY SSF55846 29 184 5.76E-48 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CVS48_RS28355 85242b94d83c0ed690928c85ae8f87d8 261 Gene3D G3DSA:3.40.80.10 38 182 1.2E-43 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CVS48_RS28355 85242b94d83c0ed690928c85ae8f87d8 261 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 38 169 3.8E-27 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CVS48_RS28355 85242b94d83c0ed690928c85ae8f87d8 261 SUPERFAMILY SSF47090 193 260 3.53E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like CVS48_RS28355 85242b94d83c0ed690928c85ae8f87d8 261 Pfam PF01471 Putative peptidoglycan binding domain 202 257 9.1E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like CVS48_RS28355 85242b94d83c0ed690928c85ae8f87d8 261 SMART SM00644 28 168 2.1E-26 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CVS48_RS22295 e5da49fe89ae62b84d933580b6942fbc 216 Pfam PF08761 dUTPase 8 169 2.4E-24 T 29-03-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 CVS48_RS22295 e5da49fe89ae62b84d933580b6942fbc 216 Gene3D G3DSA:1.10.4010.10 1 216 1.4E-46 T 29-03-2018 CVS48_RS22295 e5da49fe89ae62b84d933580b6942fbc 216 SUPERFAMILY SSF101386 5 214 4.05E-50 T 29-03-2018 CVS48_RS08065 0df6de6f1793e0afe608ed1186872c2b 225 SUPERFAMILY SSF52172 4 122 3.27E-9 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS08065 0df6de6f1793e0afe608ed1186872c2b 225 SMART SM00862 143 214 2.5E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS08065 0df6de6f1793e0afe608ed1186872c2b 225 Gene3D G3DSA:3.40.50.2300 1 112 3.5E-10 T 29-03-2018 CVS48_RS08065 0df6de6f1793e0afe608ed1186872c2b 225 Gene3D G3DSA:1.10.10.10 113 218 6.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08065 0df6de6f1793e0afe608ed1186872c2b 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 214 9.4E-5 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS08065 0df6de6f1793e0afe608ed1186872c2b 225 SUPERFAMILY SSF46894 135 215 3.68E-10 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS06040 5f5c62b5a2ba2a444f751f4a27ab7c46 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.935 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06040 5f5c62b5a2ba2a444f751f4a27ab7c46 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 6.0E-16 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06040 5f5c62b5a2ba2a444f751f4a27ab7c46 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06040 5f5c62b5a2ba2a444f751f4a27ab7c46 44 Pfam PF00468 Ribosomal protein L34 1 44 8.0E-23 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06040 5f5c62b5a2ba2a444f751f4a27ab7c46 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 3.5E-24 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS12245 44f82111ebb8af5a71a7bfda3ebaf54b 825 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 808 825 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS12245 44f82111ebb8af5a71a7bfda3ebaf54b 825 Pfam PF07715 TonB-dependent Receptor Plug Domain 182 284 7.4E-16 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS12245 44f82111ebb8af5a71a7bfda3ebaf54b 825 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 184 825 1.0E-107 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS12245 44f82111ebb8af5a71a7bfda3ebaf54b 825 SMART SM00965 82 133 9.0E-11 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS12245 44f82111ebb8af5a71a7bfda3ebaf54b 825 Gene3D G3DSA:2.170.130.10 136 298 1.9E-21 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS12245 44f82111ebb8af5a71a7bfda3ebaf54b 825 SUPERFAMILY SSF56935 139 825 3.05E-108 T 29-03-2018 CVS48_RS12245 44f82111ebb8af5a71a7bfda3ebaf54b 825 Gene3D G3DSA:2.40.170.20 300 825 1.2E-63 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12245 44f82111ebb8af5a71a7bfda3ebaf54b 825 Pfam PF00593 TonB dependent receptor 400 823 4.1E-40 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS09830 803debdd20e5a8bef2171a3f83251b48 192 Gene3D G3DSA:3.40.80.10 5 183 2.1E-47 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CVS48_RS09830 803debdd20e5a8bef2171a3f83251b48 192 SUPERFAMILY SSF55846 16 180 2.36E-58 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CVS48_RS09830 803debdd20e5a8bef2171a3f83251b48 192 SMART SM00644 22 170 6.9E-42 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CVS48_RS09830 803debdd20e5a8bef2171a3f83251b48 192 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 62 171 4.8E-23 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CVS48_RS06775 fadb8378f6d413c0522656c9d929daf2 220 SUPERFAMILY SSF52833 2 86 8.97E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS06775 fadb8378f6d413c0522656c9d929daf2 220 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 80 7.0E-12 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS06775 fadb8378f6d413c0522656c9d929daf2 220 SUPERFAMILY SSF47616 80 202 1.42E-18 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS06775 fadb8378f6d413c0522656c9d929daf2 220 Gene3D G3DSA:3.40.30.10 2 96 1.1E-22 T 29-03-2018 CVS48_RS06775 fadb8378f6d413c0522656c9d929daf2 220 Gene3D G3DSA:1.20.1050.10 97 202 1.7E-20 T 29-03-2018 CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 SUPERFAMILY SSF51735 7 262 3.08E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 Pfam PF00106 short chain dehydrogenase 12 199 1.5E-59 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 189 0.0079 T 29-03-2018 CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.1E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.1E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.1E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 Gene3D G3DSA:3.40.50.720 54 263 1.3E-66 T 29-03-2018 CVS48_RS03425 9ac82de95d766d2bb7eb9144f86c1719 263 Gene3D G3DSA:3.40.50.10090 4 53 6.3E-10 T 29-03-2018 CVS48_RS22240 e7c8c912dc6906264966547fba17ba85 221 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 10 195 31.597 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CVS48_RS22240 e7c8c912dc6906264966547fba17ba85 221 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 10 198 2.6E-73 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CVS48_RS22240 e7c8c912dc6906264966547fba17ba85 221 Pfam PF00551 Formyl transferase 10 189 3.3E-58 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS22240 e7c8c912dc6906264966547fba17ba85 221 Gene3D G3DSA:3.40.50.170 3 208 1.5E-66 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS22240 e7c8c912dc6906264966547fba17ba85 221 SUPERFAMILY SSF53328 10 208 5.1E-65 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS05035 029475f0b2041199e89ec53d97dfd5d7 446 Gene3D G3DSA:1.20.1250.20 252 432 9.6E-15 T 29-03-2018 CVS48_RS05035 029475f0b2041199e89ec53d97dfd5d7 446 SUPERFAMILY SSF103473 13 422 1.2E-27 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS05035 029475f0b2041199e89ec53d97dfd5d7 446 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 27 208 8.6E-42 T 29-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB CVS48_RS05035 029475f0b2041199e89ec53d97dfd5d7 446 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 226 421 1.8E-38 T 29-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB CVS48_RS05035 029475f0b2041199e89ec53d97dfd5d7 446 Gene3D G3DSA:1.20.1250.20 17 201 5.5E-8 T 29-03-2018 CVS48_RS18705 402701255763ce0d007725466bac8add 288 Gene3D G3DSA:3.90.850.10 34 285 1.6E-76 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS18705 402701255763ce0d007725466bac8add 288 SUPERFAMILY SSF56529 60 277 2.62E-78 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS18705 402701255763ce0d007725466bac8add 288 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 71 276 3.3E-65 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS02995 2937a677acc591e82941927591fd8cd2 123 Pfam PF01521 Iron-sulphur cluster biosynthesis 18 118 9.6E-21 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CVS48_RS02995 2937a677acc591e82941927591fd8cd2 123 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 20 123 7.4E-39 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CVS48_RS02995 2937a677acc591e82941927591fd8cd2 123 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 123 37.568 T 29-03-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 CVS48_RS02995 2937a677acc591e82941927591fd8cd2 123 SUPERFAMILY SSF89360 15 109 1.18E-31 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CVS48_RS02995 2937a677acc591e82941927591fd8cd2 123 Gene3D G3DSA:2.60.300.12 18 123 2.2E-39 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CVS48_RS02995 2937a677acc591e82941927591fd8cd2 123 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 104 121 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CVS48_RS16345 2a580d52d558b27e5a3712d31b8b69b7 705 Pfam PF00593 TonB dependent receptor 254 704 2.7E-66 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS16345 2a580d52d558b27e5a3712d31b8b69b7 705 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 67 703 2.0E-106 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS16345 2a580d52d558b27e5a3712d31b8b69b7 705 Gene3D G3DSA:2.40.170.20 177 705 7.7E-94 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS16345 2a580d52d558b27e5a3712d31b8b69b7 705 Gene3D G3DSA:2.170.130.10 25 176 9.8E-25 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS16345 2a580d52d558b27e5a3712d31b8b69b7 705 SUPERFAMILY SSF56935 55 705 2.96E-134 T 29-03-2018 CVS48_RS16345 2a580d52d558b27e5a3712d31b8b69b7 705 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 164 3.1E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS28835 0f575c3ad666bfd90ac2c8978d82cea6 314 Gene3D G3DSA:1.10.3720.10 3 301 1.5E-40 T 29-03-2018 CVS48_RS28835 0f575c3ad666bfd90ac2c8978d82cea6 314 SUPERFAMILY SSF161098 89 298 1.77E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28835 0f575c3ad666bfd90ac2c8978d82cea6 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 1.8E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS07560 b6d8df92b8ae45d7b583115485c5a975 658 Gene3D G3DSA:3.30.300.30 477 618 6.9E-5 T 29-03-2018 CVS48_RS07560 b6d8df92b8ae45d7b583115485c5a975 658 Gene3D G3DSA:2.30.38.10 403 475 2.1E-20 T 29-03-2018 CVS48_RS07560 b6d8df92b8ae45d7b583115485c5a975 658 ProSitePatterns PS00455 Putative AMP-binding domain signature. 197 208 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS07560 b6d8df92b8ae45d7b583115485c5a975 658 SUPERFAMILY SSF56801 564 613 5.49E-112 T 29-03-2018 CVS48_RS07560 b6d8df92b8ae45d7b583115485c5a975 658 SUPERFAMILY SSF56801 352 531 5.49E-112 T 29-03-2018 CVS48_RS07560 b6d8df92b8ae45d7b583115485c5a975 658 SUPERFAMILY SSF56801 11 300 5.49E-112 T 29-03-2018 CVS48_RS07560 b6d8df92b8ae45d7b583115485c5a975 658 Pfam PF00501 AMP-binding enzyme 25 482 2.8E-92 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS07560 b6d8df92b8ae45d7b583115485c5a975 658 Gene3D G3DSA:3.40.50.980 13 202 4.0E-40 T 29-03-2018 CVS48_RS07560 b6d8df92b8ae45d7b583115485c5a975 658 Gene3D G3DSA:3.40.50.980 203 402 5.4E-37 T 29-03-2018 CVS48_RS18240 f8f3b2f7718808b5b55aa62f6bd4cb05 309 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 15 219 3.7E-30 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CVS48_RS18240 f8f3b2f7718808b5b55aa62f6bd4cb05 309 PIRSF PIRSF015582 1 301 2.0E-65 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like CVS48_RS18240 f8f3b2f7718808b5b55aa62f6bd4cb05 309 Gene3D G3DSA:3.20.20.360 2 269 2.8E-36 T 29-03-2018 CVS48_RS18240 f8f3b2f7718808b5b55aa62f6bd4cb05 309 SUPERFAMILY SSF51621 12 243 6.28E-43 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS06425 18438ba5f5decb6339ef1ebf48bbd0da 63 SUPERFAMILY SSF46561 1 61 5.36E-20 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06425 18438ba5f5decb6339ef1ebf48bbd0da 63 Gene3D G3DSA:1.10.287.310 1 63 1.4E-21 T 29-03-2018 CVS48_RS06425 18438ba5f5decb6339ef1ebf48bbd0da 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 7.1E-21 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06425 18438ba5f5decb6339ef1ebf48bbd0da 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06425 18438ba5f5decb6339ef1ebf48bbd0da 63 Pfam PF00831 Ribosomal L29 protein 4 60 4.5E-21 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06425 18438ba5f5decb6339ef1ebf48bbd0da 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.408 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS08810 bb3c6f6c48c1408637ddbcb93b070b85 302 PIRSF PIRSF000103 4 297 3.2E-71 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CVS48_RS08810 bb3c6f6c48c1408637ddbcb93b070b85 302 Gene3D G3DSA:1.10.1040.10 181 297 2.8E-35 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS08810 bb3c6f6c48c1408637ddbcb93b070b85 302 Gene3D G3DSA:3.40.50.720 1 180 8.1E-35 T 29-03-2018 CVS48_RS08810 bb3c6f6c48c1408637ddbcb93b070b85 302 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 173 292 9.6E-38 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CVS48_RS08810 bb3c6f6c48c1408637ddbcb93b070b85 302 SUPERFAMILY SSF51735 9 169 5.92E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS08810 bb3c6f6c48c1408637ddbcb93b070b85 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 167 4.6E-40 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CVS48_RS08810 bb3c6f6c48c1408637ddbcb93b070b85 302 SUPERFAMILY SSF48179 172 294 6.8E-38 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS15010 fd93251af0b8324c1457db5355ddca2d 173 Gene3D G3DSA:3.10.450.160 32 173 1.4E-24 T 29-03-2018 CVS48_RS27080 b25808311a267706b117f9787365539e 189 TIGRFAM TIGR03276 Phn-HD: phosphonate degradation operons associated HDIG domain protein 3 178 2.5E-73 T 29-03-2018 IPR017670 Phosphonate degradation operon associated HDIG domain protein CVS48_RS27080 b25808311a267706b117f9787365539e 189 SUPERFAMILY SSF109604 7 61 9.01E-8 T 29-03-2018 CVS48_RS27080 b25808311a267706b117f9787365539e 189 Gene3D G3DSA:1.10.3210.10 4 174 3.6E-5 T 29-03-2018 CVS48_RS20370 329172193cdf4707e8dda5df41612cea 139 PIRSF PIRSF029394 13 139 2.1E-30 T 29-03-2018 IPR016918 Uncharacterised conserved protein UCP029394 CVS48_RS20370 329172193cdf4707e8dda5df41612cea 139 SUPERFAMILY SSF54427 21 138 3.89E-32 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS20370 329172193cdf4707e8dda5df41612cea 139 Gene3D G3DSA:3.10.450.50 17 138 8.1E-30 T 29-03-2018 CVS48_RS12800 e32dc78713c082903384e3dbdbabd108 373 Gene3D G3DSA:3.40.50.150 51 371 2.4E-31 T 29-03-2018 CVS48_RS12800 e32dc78713c082903384e3dbdbabd108 373 SUPERFAMILY SSF53335 167 310 1.27E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS12800 e32dc78713c082903384e3dbdbabd108 373 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 261 267 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CVS48_RS12800 e32dc78713c082903384e3dbdbabd108 373 Pfam PF05175 Methyltransferase small domain 185 269 5.7E-12 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CVS48_RS03150 dfbcd49cea38a275d3e31457d73bf95b 395 Pfam PF04914 DltD protein 76 393 3.6E-57 T 29-03-2018 IPR006998 DltD CVS48_RS03150 dfbcd49cea38a275d3e31457d73bf95b 395 Gene3D G3DSA:3.40.640.10 13 359 0.0076 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS05895 7f37249c28cf5d69a1921775d0c50a81 326 PIRSF PIRSF017082 1 326 1.4E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS05895 7f37249c28cf5d69a1921775d0c50a81 326 Gene3D G3DSA:3.40.190.10 125 236 2.1E-9 T 29-03-2018 CVS48_RS05895 7f37249c28cf5d69a1921775d0c50a81 326 SUPERFAMILY SSF53850 115 286 5.89E-11 T 29-03-2018 CVS48_RS05895 7f37249c28cf5d69a1921775d0c50a81 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 322 9.8E-89 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS20255 003bde801aecd6779e30f3d77979f083 226 Gene3D G3DSA:3.50.30.40 22 197 1.7E-51 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS20255 003bde801aecd6779e30f3d77979f083 226 SUPERFAMILY SSF89562 26 187 8.24E-45 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS20255 003bde801aecd6779e30f3d77979f083 226 Pfam PF03737 Aldolase/RraA 30 177 1.5E-42 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS12840 de7bbd292b1b591c7e5e60a5f782ea80 383 Pfam PF04055 Radical SAM superfamily 55 223 8.4E-27 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS12840 de7bbd292b1b591c7e5e60a5f782ea80 383 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 42 383 39.999 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CVS48_RS12840 de7bbd292b1b591c7e5e60a5f782ea80 383 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 43 383 1.3E-112 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CVS48_RS12840 de7bbd292b1b591c7e5e60a5f782ea80 383 Gene3D G3DSA:3.20.20.70 39 383 8.9E-77 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS12840 de7bbd292b1b591c7e5e60a5f782ea80 383 SMART SM00729 51 264 1.1E-5 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CVS48_RS12840 de7bbd292b1b591c7e5e60a5f782ea80 383 Pfam PF06463 Molybdenum Cofactor Synthesis C 233 358 2.4E-36 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CVS48_RS12840 de7bbd292b1b591c7e5e60a5f782ea80 383 SUPERFAMILY SSF102114 43 327 4.97E-72 T 29-03-2018 CVS48_RS12840 de7bbd292b1b591c7e5e60a5f782ea80 383 Pfam PF13394 4Fe-4S single cluster domain 58 149 3.8E-6 T 29-03-2018 CVS48_RS12840 de7bbd292b1b591c7e5e60a5f782ea80 383 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 57 68 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 2.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 2.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 2.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 232 2.0E-51 T 29-03-2018 CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 Gene3D G3DSA:3.40.50.720 1 41 3.3E-7 T 29-03-2018 CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 Gene3D G3DSA:3.40.50.720 42 239 1.7E-54 T 29-03-2018 CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22615 c47ef2c3c19399b6c6ec157508dcf875 239 SUPERFAMILY SSF51735 2 235 5.75E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS12040 5a66adc182e3a42936b8971797da7574 405 SMART SM00448 5 122 9.2E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12040 5a66adc182e3a42936b8971797da7574 405 Gene3D G3DSA:3.40.50.2300 2 133 3.3E-23 T 29-03-2018 CVS48_RS12040 5a66adc182e3a42936b8971797da7574 405 SUPERFAMILY SSF52172 5 127 2.13E-22 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS12040 5a66adc182e3a42936b8971797da7574 405 Pfam PF00072 Response regulator receiver domain 7 85 3.4E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12040 5a66adc182e3a42936b8971797da7574 405 SMART SM00052 147 388 9.2E-51 T 29-03-2018 IPR001633 EAL domain CVS48_RS12040 5a66adc182e3a42936b8971797da7574 405 SUPERFAMILY SSF141868 150 395 3.79E-61 T 29-03-2018 IPR001633 EAL domain CVS48_RS12040 5a66adc182e3a42936b8971797da7574 405 Pfam PF00563 EAL domain 150 382 2.1E-49 T 29-03-2018 IPR001633 EAL domain CVS48_RS12040 5a66adc182e3a42936b8971797da7574 405 Gene3D G3DSA:3.20.20.450 147 401 4.3E-64 T 29-03-2018 IPR001633 EAL domain CVS48_RS10615 c6cd02092fe48d738ac5896fe75d9e15 301 SUPERFAMILY SSF161098 91 279 1.96E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10615 c6cd02092fe48d738ac5896fe75d9e15 301 Gene3D G3DSA:1.10.3720.10 37 299 7.0E-39 T 29-03-2018 CVS48_RS10615 c6cd02092fe48d738ac5896fe75d9e15 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 298 1.2E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10615 c6cd02092fe48d738ac5896fe75d9e15 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 66 3.5E-5 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS25690 997e57b2c281e387d118963f23a72cfa 196 Gene3D G3DSA:3.40.50.1000 4 186 1.9E-27 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS25690 997e57b2c281e387d118963f23a72cfa 196 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 153 2.7E-29 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CVS48_RS25690 997e57b2c281e387d118963f23a72cfa 196 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 151 1.2E-36 T 29-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CVS48_RS25690 997e57b2c281e387d118963f23a72cfa 196 SUPERFAMILY SSF56784 5 182 9.98E-41 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS25690 997e57b2c281e387d118963f23a72cfa 196 Pfam PF13242 HAD-hyrolase-like 108 177 7.2E-13 T 29-03-2018 CVS48_RS25690 997e57b2c281e387d118963f23a72cfa 196 PIRSF PIRSF004682 1 188 3.7E-56 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 CVS48_RS26175 d2c81a2c5ce3d04c7fb975ca6ed0394c 299 SUPERFAMILY SSF51197 101 228 1.57E-19 T 29-03-2018 CVS48_RS26175 d2c81a2c5ce3d04c7fb975ca6ed0394c 299 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 69 222 1.9E-50 T 29-03-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 CVS48_RS26175 d2c81a2c5ce3d04c7fb975ca6ed0394c 299 Gene3D G3DSA:2.60.120.330 60 244 6.2E-47 T 29-03-2018 IPR027443 Isopenicillin N synthase-like CVS48_RS28195 fe629aa82d9432d7c83d801b9eade5f1 306 SUPERFAMILY SSF53850 91 288 7.96E-39 T 29-03-2018 CVS48_RS28195 fe629aa82d9432d7c83d801b9eade5f1 306 Pfam PF03466 LysR substrate binding domain 89 287 1.4E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS28195 fe629aa82d9432d7c83d801b9eade5f1 306 Gene3D G3DSA:3.40.190.10 183 256 3.1E-4 T 29-03-2018 CVS48_RS28195 fe629aa82d9432d7c83d801b9eade5f1 306 Gene3D G3DSA:1.10.10.10 1 82 4.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28195 fe629aa82d9432d7c83d801b9eade5f1 306 SUPERFAMILY SSF46785 2 111 1.36E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28195 fe629aa82d9432d7c83d801b9eade5f1 306 Gene3D G3DSA:3.40.190.10 83 182 2.4E-22 T 29-03-2018 CVS48_RS28195 fe629aa82d9432d7c83d801b9eade5f1 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 Gene3D G3DSA:1.10.10.10 16 94 3.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 SUPERFAMILY SSF46785 33 122 2.16E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 SUPERFAMILY SSF48008 105 238 2.25E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 Pfam PF07729 FCD domain 109 232 4.0E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 39 98 7.0E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 72 1.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 72 88 1.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 Gene3D G3DSA:1.20.120.530 95 247 1.6E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 SMART SM00345 40 98 6.3E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS20330 61aefc82c26ddf74781cdde90e24ada9 256 SMART SM00895 108 232 5.2E-17 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 Pfam PF05954 Phage late control gene D protein (GPD) 42 359 6.0E-84 T 29-03-2018 CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 SUPERFAMILY SSF69279 24 212 3.57E-47 T 29-03-2018 CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 Gene3D G3DSA:3.55.50.10 113 216 2.3E-28 T 29-03-2018 CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 Gene3D G3DSA:2.40.50.230 420 516 1.4E-29 T 29-03-2018 IPR006531 Gp5 N-terminal CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 36 529 3.8E-84 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 SUPERFAMILY SSF69279 232 402 5.61E-21 T 29-03-2018 CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 23 520 8.1E-103 T 29-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 721 878 5.0E-38 T 29-03-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 SUPERFAMILY SSF69255 414 516 2.88E-24 T 29-03-2018 CVS48_RS02080 7f7b615b247030a88846fd9890d93685 909 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 574 676 5.7E-29 T 29-03-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain CVS48_RS02175 3008f6e821016c9cb5e342ea467dfa30 281 SUPERFAMILY SSF55166 152 271 1.05E-19 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CVS48_RS02175 3008f6e821016c9cb5e342ea467dfa30 281 Gene3D G3DSA:3.30.1380.10 147 270 2.7E-17 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CVS48_RS02175 3008f6e821016c9cb5e342ea467dfa30 281 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 205 270 1.7E-10 T 29-03-2018 CVS48_RS06865 84ee39b006321ad2dfb0bf1c75093878 723 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 722 0.0 T 29-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CVS48_RS06865 84ee39b006321ad2dfb0bf1c75093878 723 Pfam PF01274 Malate synthase 18 697 1.3E-175 T 29-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CVS48_RS06865 84ee39b006321ad2dfb0bf1c75093878 723 Gene3D G3DSA:1.10.1860.10 1 88 3.8E-36 T 29-03-2018 CVS48_RS06865 84ee39b006321ad2dfb0bf1c75093878 723 Gene3D G3DSA:1.20.1220.12 590 723 6.3E-46 T 29-03-2018 CVS48_RS06865 84ee39b006321ad2dfb0bf1c75093878 723 Hamap MF_00641 Malate synthase G [glcB]. 1 723 401.397 T 29-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CVS48_RS06865 84ee39b006321ad2dfb0bf1c75093878 723 SUPERFAMILY SSF51645 4 722 3.14E-303 T 29-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CVS48_RS06865 84ee39b006321ad2dfb0bf1c75093878 723 Gene3D G3DSA:3.20.20.360 219 589 4.7E-101 T 29-03-2018 CVS48_RS06865 84ee39b006321ad2dfb0bf1c75093878 723 Gene3D G3DSA:3.20.20.360 89 208 5.4E-21 T 29-03-2018 CVS48_RS08930 db19da3a247d884712b410b5ba6bdf9e 298 SUPERFAMILY SSF46785 1 111 2.07E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08930 db19da3a247d884712b410b5ba6bdf9e 298 Gene3D G3DSA:1.10.10.10 1 85 1.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08930 db19da3a247d884712b410b5ba6bdf9e 298 Gene3D G3DSA:3.40.190.10 90 178 8.9E-19 T 29-03-2018 CVS48_RS08930 db19da3a247d884712b410b5ba6bdf9e 298 SUPERFAMILY SSF53850 90 294 9.31E-41 T 29-03-2018 CVS48_RS08930 db19da3a247d884712b410b5ba6bdf9e 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS08930 db19da3a247d884712b410b5ba6bdf9e 298 Pfam PF03466 LysR substrate binding domain 89 292 2.4E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS08930 db19da3a247d884712b410b5ba6bdf9e 298 Gene3D G3DSA:3.40.190.10 179 269 2.2E-17 T 29-03-2018 CVS48_RS17165 31d837682b9be77ab28f2527366a234f 186 PIRSF PIRSF002094 20 186 2.9E-51 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 CVS48_RS17165 31d837682b9be77ab28f2527366a234f 186 Pfam PF03938 Outer membrane protein (OmpH-like) 31 184 6.4E-36 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 CVS48_RS17165 31d837682b9be77ab28f2527366a234f 186 Gene3D G3DSA:3.30.910.20 33 185 8.1E-24 T 29-03-2018 CVS48_RS17165 31d837682b9be77ab28f2527366a234f 186 SUPERFAMILY SSF111384 43 184 2.75E-36 T 29-03-2018 IPR024930 Skp domain CVS48_RS17165 31d837682b9be77ab28f2527366a234f 186 SMART SM00935 33 185 1.4E-56 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 CVS48_RS06790 4244abba0dacf8dc4c592a948415c9f7 174 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 174 4.7E-56 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CVS48_RS06790 4244abba0dacf8dc4c592a948415c9f7 174 SUPERFAMILY SSF50249 3 174 2.09E-62 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS06790 4244abba0dacf8dc4c592a948415c9f7 174 Pfam PF00436 Single-strand binding protein family 4 109 2.9E-43 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CVS48_RS06790 4244abba0dacf8dc4c592a948415c9f7 174 Gene3D G3DSA:2.40.50.140 1 116 3.8E-43 T 29-03-2018 CVS48_RS06790 4244abba0dacf8dc4c592a948415c9f7 174 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 38.414 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CVS48_RS13610 edfd8f0f158d73ed2b0300bb28f51ab7 163 Gene3D G3DSA:3.10.450.50 2 163 1.5E-17 T 29-03-2018 CVS48_RS13610 edfd8f0f158d73ed2b0300bb28f51ab7 163 Pfam PF00866 Ring hydroxylating beta subunit 18 152 2.8E-16 T 29-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CVS48_RS13610 edfd8f0f158d73ed2b0300bb28f51ab7 163 SUPERFAMILY SSF54427 7 160 3.62E-31 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS14360 edbcf7745d0da8c7ff88079247ce6eb1 355 Gene3D G3DSA:3.40.718.10 1 210 6.0E-64 T 29-03-2018 CVS48_RS14360 edbcf7745d0da8c7ff88079247ce6eb1 355 Gene3D G3DSA:3.40.718.10 211 353 7.5E-55 T 29-03-2018 CVS48_RS14360 edbcf7745d0da8c7ff88079247ce6eb1 355 SUPERFAMILY SSF53659 3 351 3.06E-119 T 29-03-2018 CVS48_RS14360 edbcf7745d0da8c7ff88079247ce6eb1 355 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 350 9.0E-174 T 29-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CVS48_RS14360 edbcf7745d0da8c7ff88079247ce6eb1 355 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 348 2.0E-86 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CVS48_RS14360 edbcf7745d0da8c7ff88079247ce6eb1 355 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CVS48_RS14360 edbcf7745d0da8c7ff88079247ce6eb1 355 SMART SM01329 6 348 2.0E-180 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CVS48_RS20520 d998abb9c983c9fe8ae9aff84342bcf5 374 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 323 3.0E-37 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS20520 d998abb9c983c9fe8ae9aff84342bcf5 374 PIRSF PIRSF039026 6 365 3.6E-130 T 29-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CVS48_RS12080 8acc04300d0dcae5609fe3535333ced1 280 SMART SM01400 5 111 1.0E-8 T 29-03-2018 CVS48_RS12080 8acc04300d0dcae5609fe3535333ced1 280 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 19 108 1.0E-8 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CVS48_RS12080 8acc04300d0dcae5609fe3535333ced1 280 Pfam PF00156 Phosphoribosyl transferase domain 136 230 3.3E-9 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CVS48_RS12080 8acc04300d0dcae5609fe3535333ced1 280 SUPERFAMILY SSF53271 81 258 4.14E-19 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CVS48_RS12080 8acc04300d0dcae5609fe3535333ced1 280 Gene3D G3DSA:3.40.50.2020 145 265 6.0E-17 T 29-03-2018 CVS48_RS12080 8acc04300d0dcae5609fe3535333ced1 280 Gene3D G3DSA:3.40.50.2020 13 144 8.1E-17 T 29-03-2018 CVS48_RS12080 8acc04300d0dcae5609fe3535333ced1 280 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 21 246 1.2E-34 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CVS48_RS16620 b89e126efcd3de4790ddcfb949f130e0 243 Gene3D G3DSA:3.30.70.580 69 161 6.5E-16 T 29-03-2018 CVS48_RS16620 b89e126efcd3de4790ddcfb949f130e0 243 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 106 238 1.5E-36 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CVS48_RS16620 b89e126efcd3de4790ddcfb949f130e0 243 Gene3D G3DSA:3.30.70.1560 162 220 7.7E-31 T 29-03-2018 CVS48_RS16620 b89e126efcd3de4790ddcfb949f130e0 243 Pfam PF01479 S4 domain 4 39 1.0E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS16620 b89e126efcd3de4790ddcfb949f130e0 243 SUPERFAMILY SSF55174 3 88 8.11E-13 T 29-03-2018 CVS48_RS16620 b89e126efcd3de4790ddcfb949f130e0 243 Pfam PF00849 RNA pseudouridylate synthase 66 207 2.0E-11 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS16620 b89e126efcd3de4790ddcfb949f130e0 243 SMART SM00363 4 61 0.0037 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS16620 b89e126efcd3de4790ddcfb949f130e0 243 Gene3D G3DSA:3.10.290.10 1 68 1.7E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS16620 b89e126efcd3de4790ddcfb949f130e0 243 SUPERFAMILY SSF55120 65 241 5.92E-38 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 406 30.671 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 Pfam PF14450 Cell division protein FtsA 206 373 3.5E-25 T 29-03-2018 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 Pfam PF14450 Cell division protein FtsA 10 193 5.6E-10 T 29-03-2018 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 Gene3D G3DSA:3.30.420.40 3 185 1.8E-40 T 29-03-2018 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 SUPERFAMILY SSF53067 7 196 3.63E-63 T 29-03-2018 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 376 1.6E-147 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 SMART SM00842 9 195 5.8E-107 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 SUPERFAMILY SSF53067 198 375 2.32E-47 T 29-03-2018 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 Gene3D G3DSA:3.30.420.40 260 351 3.8E-19 T 29-03-2018 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 Gene3D G3DSA:3.30.420.40 196 259 1.9E-8 T 29-03-2018 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 1.9E-32 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CVS48_RS02450 d8fb57088023d947e14013487a399393 408 PIRSF PIRSF003101 1 408 6.5E-151 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CVS48_RS28540 cd48182c291fdb34d0b183827877bf52 191 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 3 180 3.0E-53 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 CVS48_RS28540 cd48182c291fdb34d0b183827877bf52 191 Pfam PF04279 Intracellular septation protein A 3 178 1.4E-64 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 CVS48_RS28540 cd48182c291fdb34d0b183827877bf52 191 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 2 179 18.284 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PIRSF PIRSF000350 44 590 5.6E-88 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 SUPERFAMILY SSF51230 3 95 1.21E-22 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 155 4.1E-70 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 534 549 4.1E-70 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 327 4.1E-70 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 276 4.1E-70 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 391 405 4.1E-70 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 556 576 4.1E-70 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 181 4.1E-70 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 434 441 4.1E-70 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 469 490 4.1E-70 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 132 454 2.3E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 131 586 1.2E-149 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 167 177 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 Gene3D G3DSA:3.90.1170.30 66 122 1.2E-4 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 SUPERFAMILY SSF51905 130 464 7.41E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 473 581 1.3E-37 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 Gene3D G3DSA:3.30.390.30 465 590 9.9E-42 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 Gene3D G3DSA:1.10.287.990 164 232 7.3E-21 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 SUPERFAMILY SSF55424 471 592 6.36E-42 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 Pfam PF00364 Biotin-requiring enzyme 6 76 4.6E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 Gene3D G3DSA:3.50.50.60 246 364 1.3E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 419 441 9.3E-39 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 153 9.3E-39 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 282 9.3E-39 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 390 406 9.3E-39 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 320 9.3E-39 T 29-03-2018 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 Gene3D G3DSA:3.50.50.60 365 464 4.6E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16690 3eddda93ea5db11ca02f9bbc907a1edf 598 Gene3D G3DSA:2.40.50.100 3 65 1.6E-13 T 29-03-2018 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 SUPERFAMILY SSF52540 581 871 3.87E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 316 328 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 Gene3D G3DSA:1.10.1780.10 2 164 7.9E-21 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 Gene3D G3DSA:1.10.8.60 365 582 1.6E-37 T 29-03-2018 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 Gene3D G3DSA:3.40.50.300 587 801 7.0E-39 T 29-03-2018 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 Gene3D G3DSA:3.40.50.300 179 364 1.8E-20 T 29-03-2018 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 SUPERFAMILY SSF52540 183 524 1.56E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 SMART SM00382 632 779 9.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 SMART SM00382 221 363 1.4E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 SMART SM01086 802 897 3.0E-7 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 SUPERFAMILY SSF81923 13 124 4.32E-11 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 699 6.6E-31 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 728 6.6E-31 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 743 757 6.6E-31 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 636 654 6.6E-31 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 226 357 1.0E-9 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 886 0.0 T 29-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 Gene3D G3DSA:1.10.8.60 802 900 3.8E-11 T 29-03-2018 CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 804 874 2.6E-12 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS08535 ff13ed3de4055690b5d410e9362c8df2 902 Pfam PF07724 AAA domain (Cdc48 subfamily) 632 796 2.7E-38 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 SUPERFAMILY SSF51735 6 247 3.14E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 Gene3D G3DSA:3.40.50.720 1 47 1.9E-10 T 29-03-2018 CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 Gene3D G3DSA:3.40.50.720 48 248 3.7E-51 T 29-03-2018 CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 4.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 4.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 4.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS11090 c3a451bf44ea940eb014d86ab5ebfb77 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 4.3E-55 T 29-03-2018 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 SUPERFAMILY SSF88946 27 134 1.96E-39 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 Pfam PF04542 Sigma-70 region 2 65 134 9.9E-19 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 9 294 51.644 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 27 292 8.9E-123 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 PRINTS PR00046 Major sigma-70 factor signature 89 102 6.1E-19 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 PRINTS PR00046 Major sigma-70 factor signature 262 277 6.1E-19 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 PRINTS PR00046 Major sigma-70 factor signature 242 254 6.1E-19 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 PRINTS PR00046 Major sigma-70 factor signature 277 288 6.1E-19 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 89 102 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 262 288 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 Gene3D G3DSA:1.10.10.10 233 294 4.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 61 290 1.2E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 Pfam PF04545 Sigma-70, region 4 238 289 1.1E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 SUPERFAMILY SSF88659 199 292 1.55E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04995 963664667a5bfe834d01db0131d1fa23 294 Gene3D G3DSA:1.10.601.10 20 134 1.3E-35 T 29-03-2018 CVS48_RS10090 e721ec6f820bd29dcf4d0a1f405bc5a8 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS10090 e721ec6f820bd29dcf4d0a1f405bc5a8 476 SUPERFAMILY SSF53720 3 473 5.37E-152 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS10090 e721ec6f820bd29dcf4d0a1f405bc5a8 476 Gene3D G3DSA:3.40.309.10 267 457 1.9E-68 T 29-03-2018 CVS48_RS10090 e721ec6f820bd29dcf4d0a1f405bc5a8 476 Gene3D G3DSA:3.40.605.10 2 266 2.7E-89 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS10090 e721ec6f820bd29dcf4d0a1f405bc5a8 476 Pfam PF00171 Aldehyde dehydrogenase family 16 471 4.4E-155 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS10090 e721ec6f820bd29dcf4d0a1f405bc5a8 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 192 280 3.6E-24 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 Gene3D G3DSA:1.20.5.170 191 214 5.6E-13 T 29-03-2018 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 SMART SM00984 307 407 1.4E-19 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 SUPERFAMILY SSF48179 191 281 4.76E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 308 406 1.5E-18 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 PIRSF PIRSF500136 1 419 8.2E-139 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 SUPERFAMILY SSF51735 1 183 2.8E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 PIRSF PIRSF000124 1 417 1.0E-48 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 Gene3D G3DSA:3.40.50.720 215 415 8.1E-52 T 29-03-2018 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 170 1.4E-32 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 Gene3D G3DSA:3.40.50.720 1 188 4.4E-34 T 29-03-2018 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 SUPERFAMILY SSF52413 302 410 2.49E-20 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04735 2028f4332dd946220e9f8978b2c3ce23 419 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 401 6.8E-113 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CVS48_RS14905 f03d806963bf0a63f8989916e3215f2e 355 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CVS48_RS14905 f03d806963bf0a63f8989916e3215f2e 355 Pfam PF01264 Chorismate synthase 10 345 5.4E-132 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CVS48_RS14905 f03d806963bf0a63f8989916e3215f2e 355 Hamap MF_00300 Chorismate synthase [aroC]. 10 354 35.674 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CVS48_RS14905 f03d806963bf0a63f8989916e3215f2e 355 SUPERFAMILY SSF103263 4 351 8.24E-144 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CVS48_RS14905 f03d806963bf0a63f8989916e3215f2e 355 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CVS48_RS14905 f03d806963bf0a63f8989916e3215f2e 355 Gene3D G3DSA:3.60.150.10 3 354 2.3E-150 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CVS48_RS14905 f03d806963bf0a63f8989916e3215f2e 355 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CVS48_RS14905 f03d806963bf0a63f8989916e3215f2e 355 TIGRFAM TIGR00033 aroC: chorismate synthase 10 349 3.6E-135 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CVS48_RS14905 f03d806963bf0a63f8989916e3215f2e 355 PIRSF PIRSF001456 3 353 2.6E-132 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 Gene3D G3DSA:3.40.190.80 202 336 2.1E-53 T 29-03-2018 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 SUPERFAMILY SSF56655 3 333 3.81E-116 T 29-03-2018 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 4 335 46.83 T 29-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 5 196 3.0E-61 T 29-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 PIRSF PIRSF500210 1 338 1.2E-126 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 Gene3D G3DSA:3.30.540.10 8 201 9.0E-60 T 29-03-2018 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 207 234 4.7E-72 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 66 92 4.7E-72 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 181 204 4.7E-72 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 150 173 4.7E-72 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 29 56 4.7E-72 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 309 334 4.7E-72 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS26685 b38afe398c2e65bb60304342d456cc9a 339 PIRSF PIRSF000904 1 339 4.9E-124 T 29-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 SUPERFAMILY SSF52777 318 554 1.96E-85 T 29-03-2018 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Gene3D G3DSA:3.30.559.10 318 556 1.4E-82 T 29-03-2018 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 331 555 2.4E-82 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Pfam PF02817 e3 binding domain 254 289 6.4E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Gene3D G3DSA:2.40.50.100 6 65 1.2E-13 T 29-03-2018 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Gene3D G3DSA:2.40.50.100 103 186 5.7E-14 T 29-03-2018 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 SUPERFAMILY SSF51230 3 96 7.73E-23 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 105 556 6.2E-197 T 29-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Gene3D G3DSA:3.90.1170.30 66 102 2.2E-4 T 29-03-2018 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Gene3D G3DSA:3.90.1170.30 187 234 0.026 T 29-03-2018 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Gene3D G3DSA:4.10.320.10 247 308 6.6E-19 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 149 178 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 SUPERFAMILY SSF51230 125 216 4.71E-21 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Pfam PF00364 Biotin-requiring enzyme 6 76 5.4E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 Pfam PF00364 Biotin-requiring enzyme 127 197 5.6E-19 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS16685 b60207e61a6a3e97b4880870f81e3dbd 556 SUPERFAMILY SSF47005 249 294 1.02E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS08730 b9ff6e73f4a439415c9509d2503bfcc7 412 Gene3D G3DSA:3.40.50.1820 132 408 4.5E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS08730 b9ff6e73f4a439415c9509d2503bfcc7 412 SUPERFAMILY SSF53474 147 399 6.56E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS08730 b9ff6e73f4a439415c9509d2503bfcc7 412 Pfam PF12697 Alpha/beta hydrolase family 162 394 9.7E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS07165 ddbf3eeb410cfd23c18446efe95d8c5f 283 Gene3D G3DSA:3.30.930.10 9 233 5.0E-46 T 29-03-2018 CVS48_RS07165 ddbf3eeb410cfd23c18446efe95d8c5f 283 Gene3D G3DSA:2.30.30.100 234 280 6.7E-13 T 29-03-2018 CVS48_RS07165 ddbf3eeb410cfd23c18446efe95d8c5f 283 SUPERFAMILY SSF50037 234 280 6.87E-7 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CVS48_RS07165 ddbf3eeb410cfd23c18446efe95d8c5f 283 Pfam PF03099 Biotin/lipoate A/B protein ligase family 64 166 3.1E-8 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CVS48_RS07165 ddbf3eeb410cfd23c18446efe95d8c5f 283 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 36 279 9.1E-34 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CVS48_RS07165 ddbf3eeb410cfd23c18446efe95d8c5f 283 SUPERFAMILY SSF55681 29 230 1.82E-37 T 29-03-2018 CVS48_RS07165 ddbf3eeb410cfd23c18446efe95d8c5f 283 Pfam PF02237 Biotin protein ligase C terminal domain 235 280 2.2E-8 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CVS48_RS11320 d172589b552112b72a8a6916d0a36ecc 415 Gene3D G3DSA:3.40.50.10540 20 415 1.1E-115 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS11320 d172589b552112b72a8a6916d0a36ecc 415 Pfam PF02515 CoA-transferase family III 26 382 9.7E-102 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS11320 d172589b552112b72a8a6916d0a36ecc 415 SUPERFAMILY SSF89796 21 405 1.44E-109 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS00645 f11945f74dbfc6de4cdb32f1a83a41c9 148 TIGRFAM TIGR03757 conj_TIGR03757: integrating conjugative element protein, PFL_4709 family 35 144 9.7E-42 T 29-03-2018 IPR011090 Integrating conjugative element protein, PFL4709 CVS48_RS00645 f11945f74dbfc6de4cdb32f1a83a41c9 148 Pfam PF07511 Protein of unknown function (DUF1525) 35 145 2.4E-40 T 29-03-2018 IPR011090 Integrating conjugative element protein, PFL4709 CVS48_RS13485 a551772d5eb522b084f1405eed1f9e9c 519 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 1.1E-33 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS13485 a551772d5eb522b084f1405eed1f9e9c 519 Gene3D G3DSA:3.40.50.970 1 180 4.9E-38 T 29-03-2018 CVS48_RS13485 a551772d5eb522b084f1405eed1f9e9c 519 SUPERFAMILY SSF52518 342 519 1.59E-36 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS13485 a551772d5eb522b084f1405eed1f9e9c 519 Gene3D G3DSA:3.40.50.970 311 519 1.3E-28 T 29-03-2018 CVS48_RS13485 a551772d5eb522b084f1405eed1f9e9c 519 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 516 1.9E-23 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS13485 a551772d5eb522b084f1405eed1f9e9c 519 SUPERFAMILY SSF52518 1 177 2.6E-39 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 Gene3D G3DSA:3.90.190.20 315 467 1.5E-38 T 29-03-2018 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 SUPERFAMILY SSF51984 6 92 2.49E-27 T 29-03-2018 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 468 42.186 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 Gene3D G3DSA:3.40.1190.10 94 314 3.1E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 Gene3D G3DSA:3.40.50.720 1 93 1.3E-13 T 29-03-2018 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 SUPERFAMILY SSF53623 91 312 1.7E-69 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 463 1.5E-164 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 SUPERFAMILY SSF53244 313 460 1.34E-45 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 Pfam PF01225 Mur ligase family, catalytic domain 7 105 6.3E-25 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 405 2.3E-19 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS02465 f7a172ab194bd1224d29419b6626ab04 468 Pfam PF08245 Mur ligase middle domain 110 294 1.6E-27 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS07355 6065f5e23f7bd9a29842c98f2c8334e1 258 SUPERFAMILY SSF48008 107 240 3.4E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS07355 6065f5e23f7bd9a29842c98f2c8334e1 258 SMART SM00895 112 235 3.4E-12 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS07355 6065f5e23f7bd9a29842c98f2c8334e1 258 SMART SM00345 44 102 2.7E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS07355 6065f5e23f7bd9a29842c98f2c8334e1 258 Gene3D G3DSA:1.20.120.530 99 252 4.1E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS07355 6065f5e23f7bd9a29842c98f2c8334e1 258 SUPERFAMILY SSF46785 40 106 1.09E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07355 6065f5e23f7bd9a29842c98f2c8334e1 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 102 2.0E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS07355 6065f5e23f7bd9a29842c98f2c8334e1 258 Pfam PF07729 FCD domain 112 234 9.7E-19 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS07355 6065f5e23f7bd9a29842c98f2c8334e1 258 Gene3D G3DSA:1.10.10.10 5 98 9.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15345 85a22f03a1b6c440d4dbe5e8f67ec393 391 Pfam PF03929 PepSY-associated TM region 12 365 3.2E-62 T 29-03-2018 IPR005625 PepSY-associated TM protein CVS48_RS15345 85a22f03a1b6c440d4dbe5e8f67ec393 391 Gene3D G3DSA:1.20.950.20 151 385 3.0E-4 T 29-03-2018 CVS48_RS05580 010bce16a45f796e9c22353a3694e4e3 206 Pfam PF01810 LysE type translocator 18 202 1.2E-32 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS05580 010bce16a45f796e9c22353a3694e4e3 206 PIRSF PIRSF006324 1 205 2.0E-54 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 SUPERFAMILY SSF109604 59 241 3.77E-71 T 29-03-2018 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 78 759 3.8E-221 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 Gene3D G3DSA:3.30.70.260 680 764 8.4E-8 T 29-03-2018 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 Pfam PF13291 ACT domain 688 761 9.4E-16 T 29-03-2018 IPR002912 ACT domain CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 SUPERFAMILY SSF81301 233 444 8.17E-60 T 29-03-2018 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 SMART SM00471 93 205 3.1E-8 T 29-03-2018 IPR003607 HD/PDEase domain CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 SUPERFAMILY SSF55021 690 762 6.41E-5 T 29-03-2018 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 SMART SM00954 287 397 1.9E-58 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 Gene3D G3DSA:3.10.20.30 434 509 5.7E-25 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 Pfam PF04607 Region found in RelA / SpoT proteins 287 395 1.3E-30 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 Pfam PF13328 HD domain 78 227 6.8E-51 T 29-03-2018 IPR003607 HD/PDEase domain CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 Gene3D G3DSA:3.30.460.10 244 377 1.9E-36 T 29-03-2018 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 Pfam PF02824 TGS domain 440 499 7.0E-24 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CVS48_RS19580 4a3b0db2a9d48bbefd86aa05b0bc0b8c 764 SUPERFAMILY SSF81271 427 500 3.05E-23 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CVS48_RS14130 05774aa43b30c97bafb13957dd283510 593 SUPERFAMILY SSF52540 351 589 2.11E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14130 05774aa43b30c97bafb13957dd283510 593 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 566 587 1.1E-6 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS14130 05774aa43b30c97bafb13957dd283510 593 SMART SM00382 377 565 9.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS14130 05774aa43b30c97bafb13957dd283510 593 Pfam PF00005 ABC transporter 369 516 3.0E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS14130 05774aa43b30c97bafb13957dd283510 593 Gene3D G3DSA:3.40.50.300 339 591 7.3E-51 T 29-03-2018 CVS48_RS14130 05774aa43b30c97bafb13957dd283510 593 Gene3D G3DSA:1.10.3470.10 8 307 6.1E-27 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS14130 05774aa43b30c97bafb13957dd283510 593 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 302 4.6E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS05770 ae470c97dc5154d4ded2777d11e6683f 237 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 17 219 41.223 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS05770 ae470c97dc5154d4ded2777d11e6683f 237 Gene3D G3DSA:3.90.870.10 12 228 2.2E-82 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CVS48_RS05770 ae470c97dc5154d4ded2777d11e6683f 237 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 21 214 7.8E-68 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS05770 ae470c97dc5154d4ded2777d11e6683f 237 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 24 213 1.4E-75 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS05770 ae470c97dc5154d4ded2777d11e6683f 237 SUPERFAMILY SSF55821 19 217 6.18E-77 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CVS48_RS15415 189f216097a1216889d29c5bfc7d96ea 169 SUPERFAMILY SSF54637 7 124 3.88E-18 T 29-03-2018 IPR029069 HotDog domain CVS48_RS15415 189f216097a1216889d29c5bfc7d96ea 169 Gene3D G3DSA:3.10.129.10 5 130 2.8E-19 T 29-03-2018 CVS48_RS15415 189f216097a1216889d29c5bfc7d96ea 169 PIRSF PIRSF020565 1 167 6.9E-53 T 29-03-2018 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted CVS48_RS14055 a815a4c4446f53cff843ca1e6c17011d 208 SUPERFAMILY SSF52499 3 201 3.79E-53 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS14055 a815a4c4446f53cff843ca1e6c17011d 208 Gene3D G3DSA:3.40.50.850 1 208 1.1E-42 T 29-03-2018 CVS48_RS14055 a815a4c4446f53cff843ca1e6c17011d 208 Pfam PF00857 Isochorismatase family 14 165 2.2E-22 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS20135 12302ffd4b84c40a12ea94e0dc7ba0e2 210 SUPERFAMILY SSF102114 45 137 1.07E-8 T 29-03-2018 CVS48_RS20135 12302ffd4b84c40a12ea94e0dc7ba0e2 210 Pfam PF13394 4Fe-4S single cluster domain 25 122 1.9E-5 T 29-03-2018 CVS48_RS20135 12302ffd4b84c40a12ea94e0dc7ba0e2 210 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 210 1.2E-109 T 29-03-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CVS48_RS20135 12302ffd4b84c40a12ea94e0dc7ba0e2 210 Gene3D G3DSA:3.20.20.70 26 203 6.0E-13 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS20135 12302ffd4b84c40a12ea94e0dc7ba0e2 210 Pfam PF04055 Radical SAM superfamily 45 122 3.2E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS20135 12302ffd4b84c40a12ea94e0dc7ba0e2 210 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 210 32.401 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CVS48_RS20135 12302ffd4b84c40a12ea94e0dc7ba0e2 210 PIRSF PIRSF000370 1 210 7.2E-37 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 SMART SM00450 159 279 7.1E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 SMART SM00450 6 135 6.1E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 ProSitePatterns PS00683 Rhodanese C-terminal signature. 263 273 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 SUPERFAMILY SSF52821 163 285 2.88E-31 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 Gene3D G3DSA:3.40.250.10 160 287 4.1E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 SUPERFAMILY SSF52821 2 142 3.93E-39 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 Gene3D G3DSA:3.40.250.10 1 150 1.9E-30 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 Pfam PF00581 Rhodanese-like domain 13 132 2.8E-15 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS11625 e35d255267294d40a6bffca68a6aa436 287 Pfam PF00581 Rhodanese-like domain 164 275 5.5E-8 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS11940 5d77b020e7344ad6ef8c82ccf579142f 218 SMART SM00895 76 203 3.0E-23 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS11940 5d77b020e7344ad6ef8c82ccf579142f 218 Gene3D G3DSA:1.20.120.530 76 215 7.6E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS11940 5d77b020e7344ad6ef8c82ccf579142f 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 66 1.8E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11940 5d77b020e7344ad6ef8c82ccf579142f 218 SUPERFAMILY SSF46785 4 90 4.29E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11940 5d77b020e7344ad6ef8c82ccf579142f 218 SMART SM00345 8 66 3.4E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11940 5d77b020e7344ad6ef8c82ccf579142f 218 Pfam PF07729 FCD domain 76 202 1.2E-24 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS11940 5d77b020e7344ad6ef8c82ccf579142f 218 SUPERFAMILY SSF48008 73 204 3.14E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS11940 5d77b020e7344ad6ef8c82ccf579142f 218 Gene3D G3DSA:1.10.10.10 1 75 7.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26655 4df365f3b79a8ff2cee131fd1f341d46 469 Gene3D G3DSA:3.30.465.10 105 248 1.2E-46 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS26655 4df365f3b79a8ff2cee131fd1f341d46 469 Gene3D G3DSA:3.30.43.10 2 104 1.1E-25 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS26655 4df365f3b79a8ff2cee131fd1f341d46 469 Pfam PF01565 FAD binding domain 52 188 4.8E-40 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS26655 4df365f3b79a8ff2cee131fd1f341d46 469 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 466 3.9E-69 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS26655 4df365f3b79a8ff2cee131fd1f341d46 469 SUPERFAMILY SSF55103 229 469 4.74E-75 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS26655 4df365f3b79a8ff2cee131fd1f341d46 469 Gene3D G3DSA:1.10.45.10 427 466 4.0E-19 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CVS48_RS26655 4df365f3b79a8ff2cee131fd1f341d46 469 SUPERFAMILY SSF56176 13 226 1.59E-71 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS22070 10600a002000114cff522e3b9e56ae6f 543 Pfam PF02470 MlaD protein 167 224 1.8E-7 T 29-03-2018 IPR003399 Mce/MlaD CVS48_RS22070 10600a002000114cff522e3b9e56ae6f 543 Pfam PF02470 MlaD protein 295 402 8.7E-13 T 29-03-2018 IPR003399 Mce/MlaD CVS48_RS22070 10600a002000114cff522e3b9e56ae6f 543 Pfam PF02470 MlaD protein 45 135 3.3E-14 T 29-03-2018 IPR003399 Mce/MlaD CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 SUPERFAMILY SSF54909 74 145 9.65E-14 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 Pfam PF01037 Lrp/AsnC ligand binding domain 78 142 3.1E-12 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 Gene3D G3DSA:3.30.70.920 62 150 3.1E-17 T 29-03-2018 CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 Gene3D G3DSA:1.10.10.10 12 61 3.5E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 59 2.0E-14 T 29-03-2018 CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 SUPERFAMILY SSF46785 11 72 2.97E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 SMART SM00344 12 118 9.9E-32 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 4.7E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 4.7E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS17380 f44bfdd85593891ef1bed0aadf2be2e1 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 4.7E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS24935 d73ebd87396075d25f2a8627e4dc610d 218 SUPERFAMILY SSF48008 79 212 3.14E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS24935 d73ebd87396075d25f2a8627e4dc610d 218 Gene3D G3DSA:1.20.120.530 70 218 1.5E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS24935 d73ebd87396075d25f2a8627e4dc610d 218 SMART SM00895 83 205 2.9E-21 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS24935 d73ebd87396075d25f2a8627e4dc610d 218 Pfam PF07729 FCD domain 83 204 3.2E-28 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS24935 d73ebd87396075d25f2a8627e4dc610d 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 2.3E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS24935 d73ebd87396075d25f2a8627e4dc610d 218 SUPERFAMILY SSF46785 11 96 4.76E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24935 d73ebd87396075d25f2a8627e4dc610d 218 SMART SM00345 15 73 8.7E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS24935 d73ebd87396075d25f2a8627e4dc610d 218 Gene3D G3DSA:1.10.10.10 4 69 3.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08895 e41ac99f160f8458ebd0165631b178aa 707 Pfam PF00593 TonB dependent receptor 349 706 9.3E-43 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS08895 e41ac99f160f8458ebd0165631b178aa 707 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 173 4.1E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS08895 e41ac99f160f8458ebd0165631b178aa 707 Gene3D G3DSA:2.170.130.10 46 168 7.3E-24 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS08895 e41ac99f160f8458ebd0165631b178aa 707 SUPERFAMILY SSF56935 57 287 2.93E-96 T 29-03-2018 CVS48_RS08895 e41ac99f160f8458ebd0165631b178aa 707 SUPERFAMILY SSF56935 325 706 2.93E-96 T 29-03-2018 CVS48_RS08895 e41ac99f160f8458ebd0165631b178aa 707 Gene3D G3DSA:2.40.170.20 169 707 2.4E-54 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS07150 d087a3b2ba622777127505f845cbe177 456 Pfam PF00534 Glycosyl transferases group 1 331 436 8.8E-8 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS07150 d087a3b2ba622777127505f845cbe177 456 SUPERFAMILY SSF53756 272 441 1.22E-9 T 29-03-2018 CVS48_RS07150 d087a3b2ba622777127505f845cbe177 456 Gene3D G3DSA:3.20.20.70 7 245 0.0031 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS07150 d087a3b2ba622777127505f845cbe177 456 Gene3D G3DSA:3.40.50.2000 246 436 5.7E-13 T 29-03-2018 CVS48_RS07150 d087a3b2ba622777127505f845cbe177 456 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 37 219 7.7E-52 T 29-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 CVS48_RS28790 dba66170ef1a5dae1e5556188f29231a 363 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 54 268 1.0E-21 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS28790 dba66170ef1a5dae1e5556188f29231a 363 SUPERFAMILY SSF111369 44 270 6.02E-15 T 29-03-2018 CVS48_RS28790 dba66170ef1a5dae1e5556188f29231a 363 Gene3D G3DSA:1.20.1600.10 63 328 4.1E-23 T 29-03-2018 CVS48_RS28790 dba66170ef1a5dae1e5556188f29231a 363 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 352 1.2E-63 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS03230 0675cdc7af511d330e89b1691eb3cbbf 592 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 382 587 3.7E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03230 0675cdc7af511d330e89b1691eb3cbbf 592 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 276 2.2E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03230 0675cdc7af511d330e89b1691eb3cbbf 592 SUPERFAMILY SSF161098 300 427 3.01E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03230 0675cdc7af511d330e89b1691eb3cbbf 592 SUPERFAMILY SSF161098 456 589 3.01E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03230 0675cdc7af511d330e89b1691eb3cbbf 592 Gene3D G3DSA:1.10.3720.10 302 591 2.4E-32 T 29-03-2018 CVS48_RS03230 0675cdc7af511d330e89b1691eb3cbbf 592 Gene3D G3DSA:1.10.3720.10 12 284 6.1E-34 T 29-03-2018 CVS48_RS03230 0675cdc7af511d330e89b1691eb3cbbf 592 SUPERFAMILY SSF161098 5 282 1.57E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10060 47a5648c7334c71db79a87974be73ba4 459 Gene3D G3DSA:1.20.1250.20 1 184 4.6E-28 T 29-03-2018 CVS48_RS10060 47a5648c7334c71db79a87974be73ba4 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 144 6.1E-7 T 29-03-2018 CVS48_RS10060 47a5648c7334c71db79a87974be73ba4 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 247 272 6.1E-7 T 29-03-2018 CVS48_RS10060 47a5648c7334c71db79a87974be73ba4 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 56 78 6.1E-7 T 29-03-2018 CVS48_RS10060 47a5648c7334c71db79a87974be73ba4 459 Gene3D G3DSA:1.20.1250.20 242 451 3.9E-25 T 29-03-2018 CVS48_RS10060 47a5648c7334c71db79a87974be73ba4 459 SUPERFAMILY SSF103473 233 451 4.45E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS10060 47a5648c7334c71db79a87974be73ba4 459 SUPERFAMILY SSF103473 3 177 4.45E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS10060 47a5648c7334c71db79a87974be73ba4 459 Pfam PF07690 Major Facilitator Superfamily 5 401 2.8E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS20905 dd996c941a155db032d854a58a43866b 193 Pfam PF03358 NADPH-dependent FMN reductase 6 150 1.3E-29 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CVS48_RS20905 dd996c941a155db032d854a58a43866b 193 Gene3D G3DSA:3.40.50.360 2 181 1.2E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS20905 dd996c941a155db032d854a58a43866b 193 TIGRFAM TIGR03566 FMN_reduc_MsuE: FMN reductase 6 177 4.0E-78 T 29-03-2018 IPR019912 FMN reductase, MsuE-like KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 CVS48_RS20905 dd996c941a155db032d854a58a43866b 193 SUPERFAMILY SSF52218 1 186 7.9E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS20885 f6079da7dabb2e64c7cb2530d91308ef 126 Gene3D G3DSA:1.10.1660.10 6 62 1.6E-19 T 29-03-2018 CVS48_RS20885 f6079da7dabb2e64c7cb2530d91308ef 126 Gene3D G3DSA:1.10.1660.10 63 126 2.5E-12 T 29-03-2018 CVS48_RS20885 f6079da7dabb2e64c7cb2530d91308ef 126 SMART SM00422 10 78 5.1E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS20885 f6079da7dabb2e64c7cb2530d91308ef 126 ProSitePatterns PS00552 MerR-type HTH domain signature. 13 35 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS20885 f6079da7dabb2e64c7cb2530d91308ef 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 2.6E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS20885 f6079da7dabb2e64c7cb2530d91308ef 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 2.6E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS20885 f6079da7dabb2e64c7cb2530d91308ef 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 65 2.6E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS20885 f6079da7dabb2e64c7cb2530d91308ef 126 Pfam PF13411 MerR HTH family regulatory protein 11 72 6.0E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS20885 f6079da7dabb2e64c7cb2530d91308ef 126 SUPERFAMILY SSF46955 10 118 1.39E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 Gene3D G3DSA:1.20.120.430 2 69 3.8E-12 T 29-03-2018 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 Gene3D G3DSA:1.20.120.430 255 370 9.8E-14 T 29-03-2018 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 Gene3D G3DSA:1.20.120.430 70 254 5.7E-46 T 29-03-2018 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 362 442 4.2E-25 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 5 442 1.0E-168 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 Pfam PF01926 50S ribosome-binding GTPase 7 123 1.1E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 Pfam PF01926 50S ribosome-binding GTPase 189 306 8.3E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 SMART SM00382 3 146 1.1 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 SMART SM00382 185 328 0.065 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 93 1.4E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 1.4E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 186 352 7.7E-24 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 161 2.4E-17 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 PIRSF PIRSF006485 3 450 2.7E-168 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 SUPERFAMILY SSF52540 6 170 1.33E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 SUPERFAMILY SSF52540 141 448 1.13E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 Gene3D G3DSA:3.30.300.20 371 443 2.5E-25 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS14715 f35a04405fea9cd0da556fa0ed8e5ec2 452 Hamap MF_00195 GTPase Der [der]. 4 445 37.727 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CVS48_RS00155 c00c353ddcb722ad711d734ef9efbfb3 375 Gene3D G3DSA:3.30.390.10 2 132 1.1E-33 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS00155 c00c353ddcb722ad711d734ef9efbfb3 375 SUPERFAMILY SSF54826 4 128 7.53E-30 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS00155 c00c353ddcb722ad711d734ef9efbfb3 375 SMART SM00922 149 247 1.1E-27 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CVS48_RS00155 c00c353ddcb722ad711d734ef9efbfb3 375 Gene3D G3DSA:3.20.20.120 133 360 1.3E-60 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS00155 c00c353ddcb722ad711d734ef9efbfb3 375 SUPERFAMILY SSF51604 115 367 7.99E-70 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS00155 c00c353ddcb722ad711d734ef9efbfb3 375 Pfam PF13378 Enolase C-terminal domain-like 153 361 2.1E-56 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS00155 c00c353ddcb722ad711d734ef9efbfb3 375 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 19 127 5.8E-21 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 Pfam PF13432 Tetratricopeptide repeat 179 233 6.7E-6 T 29-03-2018 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 Gene3D G3DSA:1.25.40.10 49 115 1.4E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 Gene3D G3DSA:1.10.287.1110 116 128 1.4E-4 T 29-03-2018 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 Gene3D G3DSA:1.10.287.1110 182 195 0.087 T 29-03-2018 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 Pfam PF14559 Tetratricopeptide repeat 73 129 5.6E-8 T 29-03-2018 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 SMART SM00028 199 232 0.024 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 SMART SM00028 97 130 0.012 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 SMART SM00028 165 198 0.57 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 SUPERFAMILY SSF48452 71 235 9.29E-28 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 Gene3D G3DSA:1.25.40.10 196 244 2.4E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS14090 df8a07d3d69abec11a8fc674fc8b73a2 244 Gene3D G3DSA:1.25.40.10 129 181 8.5E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 Gene3D G3DSA:3.50.50.60 1 157 2.8E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 Gene3D G3DSA:3.40.50.720 158 182 1.3E-4 T 29-03-2018 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 9 198 2.3E-27 T 29-03-2018 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 128 137 1.7E-7 T 29-03-2018 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 1.7E-7 T 29-03-2018 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.7E-7 T 29-03-2018 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 SUPERFAMILY SSF51905 169 205 1.64E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 SUPERFAMILY SSF51905 283 405 1.64E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 SUPERFAMILY SSF51905 4 221 1.0E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09985 5c59f146477518a4747ba416ecbb6406 422 Gene3D G3DSA:3.50.50.60 183 409 5.6E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05085 43f4d5f7a0a636c33e0e19be322f5a3a 81 PIRSF PIRSF003113 1 81 4.4E-25 T 29-03-2018 IPR002634 BolA protein CVS48_RS05085 43f4d5f7a0a636c33e0e19be322f5a3a 81 Gene3D G3DSA:3.30.300.90 2 81 6.9E-30 T 29-03-2018 CVS48_RS05085 43f4d5f7a0a636c33e0e19be322f5a3a 81 SUPERFAMILY SSF82657 2 80 1.18E-29 T 29-03-2018 IPR002634 BolA protein CVS48_RS05085 43f4d5f7a0a636c33e0e19be322f5a3a 81 Pfam PF01722 BolA-like protein 23 75 3.1E-21 T 29-03-2018 IPR002634 BolA protein CVS48_RS12110 6a01fd173639a9814d62ba6b5945d6bf 347 SUPERFAMILY SSF49503 129 286 3.14E-50 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS12110 6a01fd173639a9814d62ba6b5945d6bf 347 Pfam PF06481 COX Aromatic Rich Motif 244 289 1.5E-20 T 29-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 CVS48_RS12110 6a01fd173639a9814d62ba6b5945d6bf 347 SUPERFAMILY SSF81464 15 114 5.89E-23 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12110 6a01fd173639a9814d62ba6b5945d6bf 347 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 157 227 1.1E-6 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12110 6a01fd173639a9814d62ba6b5945d6bf 347 Gene3D G3DSA:1.10.287.90 25 110 1.1E-17 T 29-03-2018 CVS48_RS12110 6a01fd173639a9814d62ba6b5945d6bf 347 PIRSF PIRSF000292 1 312 2.4E-125 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CVS48_RS12110 6a01fd173639a9814d62ba6b5945d6bf 347 Gene3D G3DSA:2.60.40.420 119 285 3.9E-49 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS12110 6a01fd173639a9814d62ba6b5945d6bf 347 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 11 243 1.5E-108 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CVS48_RS23810 1ea770a08d29ade1a2de9a0ca165bae4 415 Pfam PF13692 Glycosyl transferases group 1 229 366 3.3E-15 T 29-03-2018 CVS48_RS23810 1ea770a08d29ade1a2de9a0ca165bae4 415 SUPERFAMILY SSF53756 2 399 3.14E-53 T 29-03-2018 CVS48_RS23810 1ea770a08d29ade1a2de9a0ca165bae4 415 Pfam PF13579 Glycosyl transferase 4-like domain 15 202 4.7E-29 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS23810 1ea770a08d29ade1a2de9a0ca165bae4 415 Gene3D G3DSA:3.40.50.2000 216 386 9.1E-28 T 29-03-2018 CVS48_RS23810 1ea770a08d29ade1a2de9a0ca165bae4 415 Gene3D G3DSA:3.40.50.2000 1 215 7.7E-24 T 29-03-2018 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 Pfam PF00258 Flavodoxin 52 180 2.0E-28 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00369 Flavodoxin signature 99 110 6.4E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00369 Flavodoxin signature 131 141 6.4E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00369 Flavodoxin signature 155 174 6.4E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00369 Flavodoxin signature 51 64 6.4E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 Gene3D G3DSA:3.40.50.80 312 456 6.6E-25 T 29-03-2018 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 Pfam PF00175 Oxidoreductase NAD-binding domain 326 430 6.9E-9 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 Gene3D G3DSA:3.40.50.360 21 191 1.0E-37 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 SUPERFAMILY SSF52218 50 187 2.29E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 SUPERFAMILY SSF63380 207 320 3.7E-15 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 393 409 1.5E-10 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 325 344 1.5E-10 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 349 358 1.5E-10 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 289 298 1.5E-10 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 261 268 1.5E-10 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 416 424 1.5E-10 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 Gene3D G3DSA:2.40.30.10 198 309 3.5E-14 T 29-03-2018 CVS48_RS22665 b7464215716b1c9c25dd5fec7491a4dc 457 SUPERFAMILY SSF52343 315 457 2.36E-34 T 29-03-2018 CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 Pfam PF06445 GyrI-like small molecule binding domain 129 277 1.8E-28 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 Gene3D G3DSA:3.20.80.10 124 277 6.4E-27 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 64 106 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 SUPERFAMILY SSF46689 63 112 1.48E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 SUPERFAMILY SSF55136 127 277 6.49E-33 T 29-03-2018 CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 SUPERFAMILY SSF46689 10 58 2.6E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 Pfam PF12833 Helix-turn-helix domain 33 111 9.7E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 Gene3D G3DSA:1.10.10.60 68 123 1.1E-13 T 29-03-2018 CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 Gene3D G3DSA:1.10.10.60 6 67 2.2E-11 T 29-03-2018 CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 SMART SM00871 125 277 3.6E-35 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CVS48_RS05905 aeaae6a398bad26a355a193d77f68dec 277 SMART SM00342 27 110 1.2E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS11490 808356499dedd49a0feecd03d1e74c77 4888 Pfam PF05860 haemagglutination activity domain 43 154 8.1E-25 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS11490 808356499dedd49a0feecd03d1e74c77 4888 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 76 151 4.5E-24 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS11490 808356499dedd49a0feecd03d1e74c77 4888 Gene3D G3DSA:2.160.20.10 4385 4562 0.077 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS11490 808356499dedd49a0feecd03d1e74c77 4888 Gene3D G3DSA:2.160.20.10 36 346 2.6E-52 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS11490 808356499dedd49a0feecd03d1e74c77 4888 SUPERFAMILY SSF51126 43 348 1.91E-43 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS11490 808356499dedd49a0feecd03d1e74c77 4888 SMART SM00912 41 154 3.5E-41 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS07360 b678eef956babfd2d1247aa6688772e0 213 SMART SM00903 19 171 1.3E-23 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS07360 b678eef956babfd2d1247aa6688772e0 213 SUPERFAMILY SSF50475 3 192 2.31E-45 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS07360 b678eef956babfd2d1247aa6688772e0 213 Pfam PF01613 Flavin reductase like domain 22 161 4.2E-21 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS07360 b678eef956babfd2d1247aa6688772e0 213 Gene3D G3DSA:2.30.110.10 9 188 1.1E-46 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS09605 79536f4d7aa9d1afc8fa8814133a9fb5 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CVS48_RS09605 79536f4d7aa9d1afc8fa8814133a9fb5 338 Gene3D G3DSA:3.40.190.10 140 223 1.5E-16 T 29-03-2018 CVS48_RS09605 79536f4d7aa9d1afc8fa8814133a9fb5 338 SMART SM00062 34 263 4.8E-42 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS09605 79536f4d7aa9d1afc8fa8814133a9fb5 338 Gene3D G3DSA:3.40.190.10 24 139 4.7E-12 T 29-03-2018 CVS48_RS09605 79536f4d7aa9d1afc8fa8814133a9fb5 338 SUPERFAMILY SSF53850 25 257 6.29E-42 T 29-03-2018 CVS48_RS09605 79536f4d7aa9d1afc8fa8814133a9fb5 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 253 9.4E-27 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS21840 9a495567e4680bb648b5bde1847187b7 618 Pfam PF00501 AMP-binding enzyme 24 483 4.8E-88 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS21840 9a495567e4680bb648b5bde1847187b7 618 Gene3D G3DSA:3.30.300.30 478 614 4.2E-15 T 29-03-2018 CVS48_RS21840 9a495567e4680bb648b5bde1847187b7 618 Gene3D G3DSA:3.40.50.980 207 410 4.3E-39 T 29-03-2018 CVS48_RS21840 9a495567e4680bb648b5bde1847187b7 618 SUPERFAMILY SSF56801 16 305 1.83E-114 T 29-03-2018 CVS48_RS21840 9a495567e4680bb648b5bde1847187b7 618 SUPERFAMILY SSF56801 355 612 1.83E-114 T 29-03-2018 CVS48_RS21840 9a495567e4680bb648b5bde1847187b7 618 Gene3D G3DSA:3.40.50.980 17 206 3.7E-37 T 29-03-2018 CVS48_RS21840 9a495567e4680bb648b5bde1847187b7 618 Gene3D G3DSA:2.30.38.10 411 477 1.1E-14 T 29-03-2018 CVS48_RS21840 9a495567e4680bb648b5bde1847187b7 618 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS28810 db1a84c2b393e736d52d3f02bf726526 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 423 4.3E-89 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS28810 db1a84c2b393e736d52d3f02bf726526 520 Gene3D G3DSA:3.10.105.10 297 489 1.8E-44 T 29-03-2018 CVS48_RS28810 db1a84c2b393e736d52d3f02bf726526 520 PIRSF PIRSF002741 8 519 2.0E-94 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS28810 db1a84c2b393e736d52d3f02bf726526 520 SUPERFAMILY SSF53850 29 507 9.06E-120 T 29-03-2018 CVS48_RS28810 db1a84c2b393e736d52d3f02bf726526 520 Gene3D G3DSA:3.90.76.10 43 151 3.8E-31 T 29-03-2018 CVS48_RS28810 db1a84c2b393e736d52d3f02bf726526 520 Gene3D G3DSA:3.40.190.10 152 296 1.9E-34 T 29-03-2018 CVS48_RS25615 633c38cb88dc509a411ef00be54b6684 166 Pfam PF08281 Sigma-70, region 4 104 155 8.7E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25615 633c38cb88dc509a411ef00be54b6684 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 160 6.1E-15 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25615 633c38cb88dc509a411ef00be54b6684 166 SUPERFAMILY SSF88659 90 162 6.54E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25615 633c38cb88dc509a411ef00be54b6684 166 Gene3D G3DSA:1.10.10.10 60 163 4.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02190 f96c2298cdaf331a372baf90cd19826b 327 Gene3D G3DSA:3.40.1730.10 10 306 6.5E-36 T 29-03-2018 CVS48_RS02190 f96c2298cdaf331a372baf90cd19826b 327 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 12 143 4.9E-34 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 CVS48_RS02190 f96c2298cdaf331a372baf90cd19826b 327 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 13 140 7.3E-26 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 CVS48_RS18355 e77e956239be89ce83738ace3d3a8553 380 Pfam PF00149 Calcineurin-like phosphoesterase 148 314 2.4E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS18355 e77e956239be89ce83738ace3d3a8553 380 Gene3D G3DSA:3.60.21.10 145 365 4.5E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS18355 e77e956239be89ce83738ace3d3a8553 380 SUPERFAMILY SSF56300 143 374 1.83E-35 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS00600 f810433e6a2bd2c3e747000359b449e1 615 SUPERFAMILY SSF109604 67 165 5.14E-5 T 29-03-2018 CVS48_RS00600 f810433e6a2bd2c3e747000359b449e1 615 TIGRFAM TIGR03760 ICE_TraI_Pfluor: integrating conjugative element relaxase, PFGI-1 class 25 242 2.8E-91 T 29-03-2018 IPR022391 Integrating conjugative element relaxase, PFGI-1 class CVS48_RS00600 f810433e6a2bd2c3e747000359b449e1 615 Gene3D G3DSA:1.10.3210.10 59 252 3.3E-7 T 29-03-2018 CVS48_RS00600 f810433e6a2bd2c3e747000359b449e1 615 SUPERFAMILY SSF46785 487 613 2.18E-43 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00600 f810433e6a2bd2c3e747000359b449e1 615 Pfam PF07514 Putative helicase 26 339 7.6E-128 T 29-03-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative CVS48_RS00600 f810433e6a2bd2c3e747000359b449e1 615 Gene3D G3DSA:2.40.10.200 508 612 1.6E-38 T 29-03-2018 CVS48_RS00600 f810433e6a2bd2c3e747000359b449e1 615 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 490 613 4.7E-48 T 29-03-2018 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal CVS48_RS26280 53fe3fd3bd811b44ed5fb8287e08eb17 166 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 151 3.6E-29 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS24555 ac8b94e8ff68143c14b2cbd0347c02d9 165 Gene3D G3DSA:3.30.50.20 73 145 7.2E-17 T 29-03-2018 CVS48_RS24555 ac8b94e8ff68143c14b2cbd0347c02d9 165 Pfam PF07102 Protein of unknown function (DUF1364) 58 121 2.0E-14 T 29-03-2018 IPR010774 Protein of unknown function DUF1364 CVS48_RS10310 5e08d1197d9a9266ac678d66529fbb5f 333 PIRSF PIRSF017082 1 332 2.5E-72 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS10310 5e08d1197d9a9266ac678d66529fbb5f 333 Gene3D G3DSA:3.40.190.10 132 242 1.2E-11 T 29-03-2018 CVS48_RS10310 5e08d1197d9a9266ac678d66529fbb5f 333 SUPERFAMILY SSF53850 122 299 1.01E-14 T 29-03-2018 CVS48_RS10310 5e08d1197d9a9266ac678d66529fbb5f 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 329 7.7E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 Gene3D G3DSA:1.10.10.10 13 97 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 SUPERFAMILY SSF53850 103 273 5.07E-18 T 29-03-2018 CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 Gene3D G3DSA:3.40.190.10 184 274 4.9E-9 T 29-03-2018 CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 Pfam PF03466 LysR substrate binding domain 101 297 2.8E-16 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 74 2.7E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 SUPERFAMILY SSF46785 11 122 9.91E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 Gene3D G3DSA:3.40.190.10 98 183 8.4E-9 T 29-03-2018 CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15955 21ae3396d1207fff141b133b344b68f6 337 Gene3D G3DSA:1.10.10.10 289 337 7.6E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12610 ecce41029b60c523482142fb8e0435f1 327 SUPERFAMILY SSF53850 113 289 1.61E-14 T 29-03-2018 CVS48_RS12610 ecce41029b60c523482142fb8e0435f1 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 322 5.4E-87 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS12610 ecce41029b60c523482142fb8e0435f1 327 PIRSF PIRSF017082 1 327 5.2E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS12610 ecce41029b60c523482142fb8e0435f1 327 Gene3D G3DSA:3.40.190.10 128 238 2.6E-10 T 29-03-2018 CVS48_RS15360 da8c46028fea445942834170a0e8b387 267 Pfam PF02311 AraC-like ligand binding domain 39 125 2.6E-7 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS15360 da8c46028fea445942834170a0e8b387 267 SMART SM00342 181 263 2.4E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS15360 da8c46028fea445942834170a0e8b387 267 Gene3D G3DSA:1.10.10.60 161 216 4.0E-9 T 29-03-2018 CVS48_RS15360 da8c46028fea445942834170a0e8b387 267 Gene3D G3DSA:1.10.10.60 217 267 3.0E-10 T 29-03-2018 CVS48_RS15360 da8c46028fea445942834170a0e8b387 267 SUPERFAMILY SSF51182 22 186 2.49E-20 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS15360 da8c46028fea445942834170a0e8b387 267 SUPERFAMILY SSF46689 217 265 8.06E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS15360 da8c46028fea445942834170a0e8b387 267 Pfam PF12833 Helix-turn-helix domain 190 264 8.9E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS15360 da8c46028fea445942834170a0e8b387 267 Gene3D G3DSA:2.60.120.10 1 114 4.0E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 SUPERFAMILY SSF53901 1 266 7.61E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 3.8E-120 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 SUPERFAMILY SSF53901 272 392 6.73E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 Pfam PF00108 Thiolase, N-terminal domain 5 261 3.0E-56 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 PIRSF PIRSF000429 1 394 5.2E-115 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 Pfam PF02803 Thiolase, C-terminal domain 271 391 1.2E-44 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 Gene3D G3DSA:3.40.47.10 271 390 3.2E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 Gene3D G3DSA:3.40.47.10 1 270 2.6E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS20605 9b17d6c783b09a45e78f2d709e459a93 394 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 38 668 9.0E-218 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 Pfam PF00271 Helicase conserved C-terminal domain 482 591 3.6E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 SUPERFAMILY SSF52540 178 457 1.92E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 SUPERFAMILY SSF50249 26 174 2.57E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 Gene3D G3DSA:3.40.50.300 252 460 8.1E-33 T 29-03-2018 CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 SMART SM00487 267 463 3.5E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 Pfam PF00270 DEAD/DEAH box helicase 275 434 7.1E-16 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 Gene3D G3DSA:2.40.50.140 52 144 8.4E-11 T 29-03-2018 CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 Gene3D G3DSA:3.40.50.300 461 633 7.7E-29 T 29-03-2018 CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 SUPERFAMILY SSF52540 456 657 1.65E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 SMART SM00490 509 592 2.8E-21 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS19405 a5a3a1d235e8ed49ec404c72f77daca1 696 Pfam PF17191 RecG wedge domain 26 171 3.9E-14 T 29-03-2018 IPR033454 RecG, wedge domain CVS48_RS25965 d5b9b29cb0462e065a5dd410c3c86ebb 607 SUPERFAMILY SSF52091 456 565 6.47E-15 T 29-03-2018 IPR002645 STAS domain CVS48_RS25965 d5b9b29cb0462e065a5dd410c3c86ebb 607 Pfam PF01740 STAS domain 458 560 1.2E-11 T 29-03-2018 IPR002645 STAS domain CVS48_RS25965 d5b9b29cb0462e065a5dd410c3c86ebb 607 Pfam PF00916 Sulfate permease family 25 398 3.0E-85 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CVS48_RS25965 d5b9b29cb0462e065a5dd410c3c86ebb 607 Gene3D G3DSA:3.30.750.24 419 569 1.0E-18 T 29-03-2018 IPR002645 STAS domain CVS48_RS23010 d651efc797b07919ab567bf53630a3f4 338 Pfam PF14525 AraC-binding-like domain 24 200 5.5E-28 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CVS48_RS23010 d651efc797b07919ab567bf53630a3f4 338 SMART SM00342 237 322 6.2E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS23010 d651efc797b07919ab567bf53630a3f4 338 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 274 318 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS23010 d651efc797b07919ab567bf53630a3f4 338 Gene3D G3DSA:1.10.10.60 201 275 1.2E-14 T 29-03-2018 CVS48_RS23010 d651efc797b07919ab567bf53630a3f4 338 SUPERFAMILY SSF46689 221 271 6.53E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS23010 d651efc797b07919ab567bf53630a3f4 338 Pfam PF12833 Helix-turn-helix domain 243 324 1.9E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS23010 d651efc797b07919ab567bf53630a3f4 338 Gene3D G3DSA:2.60.120.280 44 200 3.0E-5 T 29-03-2018 CVS48_RS23010 d651efc797b07919ab567bf53630a3f4 338 Gene3D G3DSA:1.10.10.60 276 336 2.2E-8 T 29-03-2018 CVS48_RS23675 1c856988b2169d7cf4855ecea0f3013e 228 SMART SM00318 76 208 4.3E-24 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CVS48_RS23675 1c856988b2169d7cf4855ecea0f3013e 228 SUPERFAMILY SSF50199 77 215 3.4E-31 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CVS48_RS23675 1c856988b2169d7cf4855ecea0f3013e 228 ProSitePatterns PS01123 Thermonuclease family signature 1. 87 111 - T 29-03-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CVS48_RS23675 1c856988b2169d7cf4855ecea0f3013e 228 Pfam PF00565 Staphylococcal nuclease homologue 101 208 5.3E-17 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CVS48_RS23675 1c856988b2169d7cf4855ecea0f3013e 228 Gene3D G3DSA:2.40.50.90 74 214 6.6E-33 T 29-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CVS48_RS07680 97c1d6453134f74b3a4204cb913d5cd7 262 Gene3D G3DSA:3.40.190.10 23 120 1.1E-25 T 29-03-2018 CVS48_RS07680 97c1d6453134f74b3a4204cb913d5cd7 262 Gene3D G3DSA:3.40.190.10 121 262 9.3E-60 T 29-03-2018 CVS48_RS07680 97c1d6453134f74b3a4204cb913d5cd7 262 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 22 260 6.7E-78 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS07680 97c1d6453134f74b3a4204cb913d5cd7 262 SUPERFAMILY SSF53850 26 262 2.17E-90 T 29-03-2018 CVS48_RS07680 97c1d6453134f74b3a4204cb913d5cd7 262 PIRSF PIRSF002854 2 262 2.8E-110 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS07680 97c1d6453134f74b3a4204cb913d5cd7 262 Pfam PF03180 NLPA lipoprotein 27 262 1.7E-103 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS07910 b008009d203bf9145e5cf06d188ba180 188 SUPERFAMILY SSF54427 13 137 4.75E-8 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS07910 b008009d203bf9145e5cf06d188ba180 188 Gene3D G3DSA:3.10.450.50 9 141 3.8E-6 T 29-03-2018 CVS48_RS23685 d354ce80995deb99a6e504cdf8f8fa6a 704 SUPERFAMILY SSF52540 12 640 1.08E-123 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23685 d354ce80995deb99a6e504cdf8f8fa6a 704 Gene3D G3DSA:3.40.50.300 444 668 5.0E-33 T 29-03-2018 CVS48_RS23685 d354ce80995deb99a6e504cdf8f8fa6a 704 Gene3D G3DSA:3.40.50.300 315 418 1.1E-16 T 29-03-2018 CVS48_RS23685 d354ce80995deb99a6e504cdf8f8fa6a 704 Gene3D G3DSA:3.40.50.300 11 314 1.5E-51 T 29-03-2018 CVS48_RS23685 d354ce80995deb99a6e504cdf8f8fa6a 704 Pfam PF00580 UvrD/REP helicase N-terminal domain 41 304 4.8E-51 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CVS48_RS23685 d354ce80995deb99a6e504cdf8f8fa6a 704 Pfam PF13361 UvrD-like helicase C-terminal domain 311 464 2.5E-17 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CVS48_RS23685 d354ce80995deb99a6e504cdf8f8fa6a 704 Pfam PF13361 UvrD-like helicase C-terminal domain 570 634 2.3E-19 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CVS48_RS27030 04b618095ce31224f4ac175b7d5da4f0 284 SUPERFAMILY SSF46785 45 117 1.95E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27030 04b618095ce31224f4ac175b7d5da4f0 284 SMART SM00346 45 135 1.8E-18 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS27030 04b618095ce31224f4ac175b7d5da4f0 284 Gene3D G3DSA:3.30.450.40 115 279 6.3E-32 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS27030 04b618095ce31224f4ac175b7d5da4f0 284 Pfam PF09339 IclR helix-turn-helix domain 47 98 1.5E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS27030 04b618095ce31224f4ac175b7d5da4f0 284 Gene3D G3DSA:1.10.10.10 24 106 5.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27030 04b618095ce31224f4ac175b7d5da4f0 284 Pfam PF01614 Bacterial transcriptional regulator 177 275 8.7E-6 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS27030 04b618095ce31224f4ac175b7d5da4f0 284 SUPERFAMILY SSF55781 117 277 1.24E-29 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS01935 7083ea7e8e715a98b41036b095f56793 507 SUPERFAMILY SSF117457 320 488 2.88E-62 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CVS48_RS01935 7083ea7e8e715a98b41036b095f56793 507 PIRSF PIRSF001394 1 507 4.8E-210 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CVS48_RS01935 7083ea7e8e715a98b41036b095f56793 507 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 327 488 1.6E-46 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CVS48_RS01935 7083ea7e8e715a98b41036b095f56793 507 Pfam PF05683 Fumarase C-terminus 289 490 2.0E-81 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CVS48_RS01935 7083ea7e8e715a98b41036b095f56793 507 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 14 285 3.0E-63 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CVS48_RS01935 7083ea7e8e715a98b41036b095f56793 507 Gene3D G3DSA:3.20.130.10 316 489 1.2E-64 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CVS48_RS01935 7083ea7e8e715a98b41036b095f56793 507 Pfam PF05681 Fumarate hydratase (Fumerase) 12 285 8.2E-99 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CVS48_RS17990 321edb39876118c9e8063da1670c2698 437 Gene3D G3DSA:1.20.1250.20 230 437 1.5E-21 T 29-03-2018 CVS48_RS17990 321edb39876118c9e8063da1670c2698 437 Gene3D G3DSA:1.20.1250.20 14 229 8.6E-23 T 29-03-2018 CVS48_RS17990 321edb39876118c9e8063da1670c2698 437 Pfam PF07690 Major Facilitator Superfamily 69 392 4.7E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS17990 321edb39876118c9e8063da1670c2698 437 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS17990 321edb39876118c9e8063da1670c2698 437 SUPERFAMILY SSF103473 18 434 6.15E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS15735 b149287b31e10289d5e30d485ebb11d6 262 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 51 233 7.0E-66 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15735 b149287b31e10289d5e30d485ebb11d6 262 Pfam PF01578 Cytochrome C assembly protein 35 190 2.4E-27 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CVS48_RS15735 b149287b31e10289d5e30d485ebb11d6 262 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 51 68 4.2E-45 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15735 b149287b31e10289d5e30d485ebb11d6 262 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 68 88 4.2E-45 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15735 b149287b31e10289d5e30d485ebb11d6 262 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 106 126 4.2E-45 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15735 b149287b31e10289d5e30d485ebb11d6 262 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 127 147 4.2E-45 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15735 b149287b31e10289d5e30d485ebb11d6 262 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 162 188 4.2E-45 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15735 b149287b31e10289d5e30d485ebb11d6 262 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 210 234 4.2E-45 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS24970 86bbf2246cd8b7eac9903bd41aca4bd3 381 SUPERFAMILY SSF49401 233 380 1.04E-12 T 29-03-2018 IPR008966 Adhesion domain CVS48_RS24970 86bbf2246cd8b7eac9903bd41aca4bd3 381 Gene3D G3DSA:2.60.40.1090 227 380 2.3E-15 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CVS48_RS20120 a8cccf57f3f31cdaf3864de4b0701f99 350 SUPERFAMILY SSF51395 1 349 6.02E-120 T 29-03-2018 CVS48_RS20120 a8cccf57f3f31cdaf3864de4b0701f99 350 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 328 1.6E-80 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CVS48_RS20120 a8cccf57f3f31cdaf3864de4b0701f99 350 Gene3D G3DSA:3.20.20.70 1 350 1.8E-121 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS03900 fa8046c31662f11fb45eff893d0036d3 253 Gene3D G3DSA:1.10.10.10 2 84 7.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03900 fa8046c31662f11fb45eff893d0036d3 253 SUPERFAMILY SSF48008 93 241 3.92E-16 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS03900 fa8046c31662f11fb45eff893d0036d3 253 Gene3D G3DSA:1.20.120.530 85 252 3.4E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS03900 fa8046c31662f11fb45eff893d0036d3 253 SMART SM00345 30 88 9.0E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03900 fa8046c31662f11fb45eff893d0036d3 253 Pfam PF07729 FCD domain 100 233 3.8E-18 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS03900 fa8046c31662f11fb45eff893d0036d3 253 SUPERFAMILY SSF46785 22 92 3.71E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03900 fa8046c31662f11fb45eff893d0036d3 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 87 5.2E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03900 fa8046c31662f11fb45eff893d0036d3 253 SMART SM00895 98 234 1.3E-7 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 9.7E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 SMART SM00345 16 75 1.2E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 1.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 1.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 SMART SM00895 106 229 1.0E-22 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 Pfam PF07729 FCD domain 106 227 3.4E-23 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 Gene3D G3DSA:1.10.10.10 4 76 2.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 SUPERFAMILY SSF48008 105 236 6.28E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 SUPERFAMILY SSF46785 7 79 1.31E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18290 5cdab801283d340bcfa84ee52d7a4787 244 Gene3D G3DSA:1.20.120.530 105 240 3.3E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS07960 67e1cc31dd2a79957fe2a8c8eebb9193 489 PIRSF PIRSF006247 1 489 6.9E-156 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 CVS48_RS07960 67e1cc31dd2a79957fe2a8c8eebb9193 489 Pfam PF02386 Cation transport protein 38 273 7.1E-41 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CVS48_RS07960 67e1cc31dd2a79957fe2a8c8eebb9193 489 Pfam PF02386 Cation transport protein 310 483 2.4E-23 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CVS48_RS17455 65d41b324c60e0aa152e5825bfde51a5 818 Pfam PF07715 TonB-dependent Receptor Plug Domain 157 261 1.0E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS17455 65d41b324c60e0aa152e5825bfde51a5 818 Pfam PF00593 TonB dependent receptor 337 817 1.1E-47 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS17455 65d41b324c60e0aa152e5825bfde51a5 818 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 801 818 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS17455 65d41b324c60e0aa152e5825bfde51a5 818 Gene3D G3DSA:2.170.130.10 115 268 2.4E-25 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS17455 65d41b324c60e0aa152e5825bfde51a5 818 SUPERFAMILY SSF56935 114 818 2.62E-131 T 29-03-2018 CVS48_RS17455 65d41b324c60e0aa152e5825bfde51a5 818 SMART SM00965 62 113 7.5E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS17455 65d41b324c60e0aa152e5825bfde51a5 818 Gene3D G3DSA:2.40.170.20 269 818 3.0E-84 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS17455 65d41b324c60e0aa152e5825bfde51a5 818 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 159 818 6.1E-104 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS17690 89b36815b1ae6d7d5d6ad239f568bcbc 165 Gene3D G3DSA:3.40.50.300 1 163 3.6E-27 T 29-03-2018 CVS48_RS17690 89b36815b1ae6d7d5d6ad239f568bcbc 165 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 158 1.7E-44 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CVS48_RS17690 89b36815b1ae6d7d5d6ad239f568bcbc 165 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 136 3.6E-48 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CVS48_RS17690 89b36815b1ae6d7d5d6ad239f568bcbc 165 SUPERFAMILY SSF52540 3 162 9.36E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05045 b0a567240bd18f750b63988cedfa1321 353 Gene3D G3DSA:3.20.20.70 1 352 5.0E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS05045 b0a567240bd18f750b63988cedfa1321 353 SUPERFAMILY SSF51412 4 332 5.95E-59 T 29-03-2018 CVS48_RS05045 b0a567240bd18f750b63988cedfa1321 353 Pfam PF03060 Nitronate monooxygenase 4 343 1.2E-80 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 Gene3D G3DSA:3.40.50.720 2 45 1.0E-8 T 29-03-2018 CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 Gene3D G3DSA:3.40.50.720 46 248 7.8E-63 T 29-03-2018 CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.7E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.7E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.7E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.7E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.7E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.7E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.8E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.8E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.8E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 5 247 1.2E-103 T 29-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 3.9E-7 T 29-03-2018 CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 SUPERFAMILY SSF51735 5 247 4.32E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS10450 c1d451e754717b12fa7155d8838cffea 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 5.2E-64 T 29-03-2018 CVS48_RS22650 26f265fa692bb5ca8000f8ba22f97fef 171 Pfam PF10029 Predicted periplasmic protein (DUF2271) 25 163 5.8E-52 T 29-03-2018 IPR014469 Protein of unknown function DUF2271 CVS48_RS22650 26f265fa692bb5ca8000f8ba22f97fef 171 PIRSF PIRSF014995 1 171 3.1E-69 T 29-03-2018 IPR014469 Protein of unknown function DUF2271 CVS48_RS27285 fe37302749e3303a343fb59c92705cb6 554 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 3 554 4.2E-293 T 29-03-2018 IPR011975 Phenylacetic acid degradation protein PaaN2 CVS48_RS27285 fe37302749e3303a343fb59c92705cb6 554 Gene3D G3DSA:3.40.309.10 323 521 8.5E-27 T 29-03-2018 CVS48_RS27285 fe37302749e3303a343fb59c92705cb6 554 Gene3D G3DSA:3.40.605.10 85 322 1.3E-35 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS27285 fe37302749e3303a343fb59c92705cb6 554 Pfam PF00171 Aldehyde dehydrogenase family 89 503 5.1E-37 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS27285 fe37302749e3303a343fb59c92705cb6 554 SUPERFAMILY SSF53720 74 532 7.07E-59 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 SUPERFAMILY SSF46785 13 85 1.33E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 Gene3D G3DSA:1.20.120.530 89 242 5.3E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 2.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 2.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 SMART SM00345 22 81 1.1E-24 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 Gene3D G3DSA:1.10.10.10 10 81 2.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 SMART SM00895 105 233 4.6E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 Pfam PF07729 FCD domain 106 232 4.5E-22 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 SUPERFAMILY SSF48008 102 240 8.89E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS10780 5cbe591336b333445bd97a87a0d24a69 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 3.8E-24 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 SMART SM00052 405 650 3.6E-106 T 29-03-2018 IPR001633 EAL domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 SUPERFAMILY SSF141868 412 660 1.27E-85 T 29-03-2018 IPR001633 EAL domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 SUPERFAMILY SSF55785 124 234 1.1E-13 T 29-03-2018 IPR000014 PAS domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 Gene3D G3DSA:3.20.20.450 403 663 2.2E-93 T 29-03-2018 IPR001633 EAL domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 Gene3D G3DSA:3.30.70.270 235 402 4.4E-57 T 29-03-2018 CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 234 394 1.1E-33 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 Pfam PF13426 PAS domain 123 225 2.1E-8 T 29-03-2018 IPR000014 PAS domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 SMART SM00091 111 177 0.0078 T 29-03-2018 IPR000014 PAS domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 116 233 7.6E-11 T 29-03-2018 IPR000014 PAS domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 Gene3D G3DSA:3.30.450.20 96 234 6.0E-18 T 29-03-2018 CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 390 3.4E-46 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 SMART SM00267 226 395 8.2E-65 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 Pfam PF00563 EAL domain 412 645 2.9E-67 T 29-03-2018 IPR001633 EAL domain CVS48_RS15815 d672862b54822cfdb3eecd2a1b10a0f5 665 SUPERFAMILY SSF55073 242 397 3.61E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS11375 81bf745316fe1d145a9227525dd03683 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 8.3E-43 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS11375 81bf745316fe1d145a9227525dd03683 262 Gene3D G3DSA:1.10.12.10 203 262 6.2E-12 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS11375 81bf745316fe1d145a9227525dd03683 262 SUPERFAMILY SSF52096 6 261 2.34E-62 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS11375 81bf745316fe1d145a9227525dd03683 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS11375 81bf745316fe1d145a9227525dd03683 262 Gene3D G3DSA:3.90.226.10 2 200 7.1E-50 T 29-03-2018 CVS48_RS16185 129054f0ac107d5eaa78c26a897f1730 142 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 3.7E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS16185 129054f0ac107d5eaa78c26a897f1730 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 49 67 1.1E-16 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CVS48_RS16185 129054f0ac107d5eaa78c26a897f1730 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 13 38 1.1E-16 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CVS48_RS16185 129054f0ac107d5eaa78c26a897f1730 142 Gene3D G3DSA:3.30.700.10 27 140 2.8E-29 T 29-03-2018 CVS48_RS16185 129054f0ac107d5eaa78c26a897f1730 142 SUPERFAMILY SSF54523 40 141 1.73E-35 T 29-03-2018 CVS48_RS16185 129054f0ac107d5eaa78c26a897f1730 142 Pfam PF08334 Type II secretion system (T2SS), protein G 36 140 1.5E-40 T 29-03-2018 IPR013545 Type II secretion system protein G CVS48_RS16185 129054f0ac107d5eaa78c26a897f1730 142 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 12 141 2.6E-52 T 29-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 CVS48_RS16185 129054f0ac107d5eaa78c26a897f1730 142 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 33 3.0E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS16185 129054f0ac107d5eaa78c26a897f1730 142 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS15480 58983ea01d9b76d1968eda66b796327e 281 SUPERFAMILY SSF69593 52 233 1.96E-24 T 29-03-2018 CVS48_RS15480 58983ea01d9b76d1968eda66b796327e 281 SMART SM00563 91 199 2.0E-18 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CVS48_RS15480 58983ea01d9b76d1968eda66b796327e 281 Gene3D G3DSA:3.40.1130.10 46 271 7.1E-24 T 29-03-2018 CVS48_RS15480 58983ea01d9b76d1968eda66b796327e 281 Pfam PF01553 Acyltransferase 79 196 5.0E-12 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CVS48_RS14180 65a04eb4f859272129d27f91f4c3ae8d 267 Gene3D G3DSA:3.40.50.10860 1 121 1.0E-34 T 29-03-2018 CVS48_RS14180 65a04eb4f859272129d27f91f4c3ae8d 267 Gene3D G3DSA:3.40.50.720 122 262 2.8E-23 T 29-03-2018 CVS48_RS14180 65a04eb4f859272129d27f91f4c3ae8d 267 SUPERFAMILY SSF53223 3 107 3.11E-25 T 29-03-2018 CVS48_RS14180 65a04eb4f859272129d27f91f4c3ae8d 267 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 124 171 5.9E-6 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CVS48_RS14180 65a04eb4f859272129d27f91f4c3ae8d 267 SUPERFAMILY SSF51735 110 255 1.56E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS14180 65a04eb4f859272129d27f91f4c3ae8d 267 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 96 6.8E-22 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CVS48_RS27055 9dacb522480dbf2fcc58df5a2fbadb52 340 PIRSF PIRSF002825 3 332 1.4E-93 T 29-03-2018 IPR026045 Ferric binding protein CVS48_RS27055 9dacb522480dbf2fcc58df5a2fbadb52 340 Gene3D G3DSA:3.40.190.10 12 144 8.0E-15 T 29-03-2018 CVS48_RS27055 9dacb522480dbf2fcc58df5a2fbadb52 340 Pfam PF13343 Bacterial extracellular solute-binding protein 73 313 3.7E-32 T 29-03-2018 CVS48_RS27055 9dacb522480dbf2fcc58df5a2fbadb52 340 Gene3D G3DSA:3.40.190.10 145 328 6.3E-26 T 29-03-2018 CVS48_RS27055 9dacb522480dbf2fcc58df5a2fbadb52 340 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 8 336 2.8E-157 T 29-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative CVS48_RS27055 9dacb522480dbf2fcc58df5a2fbadb52 340 SUPERFAMILY SSF53850 25 329 1.09E-72 T 29-03-2018 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 SUPERFAMILY SSF51905 145 312 4.66E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 Gene3D G3DSA:3.50.50.60 4 139 1.0E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 Pfam PF14759 Reductase C-terminal 323 405 4.1E-18 T 29-03-2018 IPR028202 Reductase, C-terminal CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 Gene3D G3DSA:3.50.50.60 144 319 8.9E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 7.8E-14 T 29-03-2018 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 7.8E-14 T 29-03-2018 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.8E-14 T 29-03-2018 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 SUPERFAMILY SSF51905 6 193 5.05E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 Gene3D G3DSA:3.30.390.30 323 407 1.1E-18 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.8E-21 T 29-03-2018 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.8E-21 T 29-03-2018 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 3.8E-21 T 29-03-2018 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 3.8E-21 T 29-03-2018 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.8E-21 T 29-03-2018 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 SUPERFAMILY SSF55424 315 404 2.47E-15 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS18675 9432643c669947dae901fbd7ea9f4824 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 303 1.0E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS02025 e4d5e34a7e1e7558c8599da36d85f10c 228 Pfam PF00483 Nucleotidyl transferase 3 122 1.6E-21 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CVS48_RS02025 e4d5e34a7e1e7558c8599da36d85f10c 228 Gene3D G3DSA:3.90.550.10 1 228 1.1E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS02025 e4d5e34a7e1e7558c8599da36d85f10c 228 SUPERFAMILY SSF53448 1 223 6.98E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS19570 cf78e8fa830c0ee53f78c39c706aa4ae 210 Pfam PF00625 Guanylate kinase 9 185 1.3E-43 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CVS48_RS19570 cf78e8fa830c0ee53f78c39c706aa4ae 210 Hamap MF_00328 Guanylate kinase [gmk]. 4 187 36.091 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CVS48_RS19570 cf78e8fa830c0ee53f78c39c706aa4ae 210 Gene3D G3DSA:3.30.63.10 50 81 1.2E-23 T 29-03-2018 CVS48_RS19570 cf78e8fa830c0ee53f78c39c706aa4ae 210 Gene3D G3DSA:3.40.50.300 82 187 3.8E-28 T 29-03-2018 CVS48_RS19570 cf78e8fa830c0ee53f78c39c706aa4ae 210 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CVS48_RS19570 cf78e8fa830c0ee53f78c39c706aa4ae 210 SUPERFAMILY SSF52540 4 189 2.58E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19570 cf78e8fa830c0ee53f78c39c706aa4ae 210 Gene3D G3DSA:3.40.50.300 1 49 1.7E-4 T 29-03-2018 CVS48_RS19570 cf78e8fa830c0ee53f78c39c706aa4ae 210 SMART SM00072 5 187 4.5E-60 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CVS48_RS19570 cf78e8fa830c0ee53f78c39c706aa4ae 210 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 184 3.2E-69 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CVS48_RS23320 26a1a8fce98b653cab84dbe93a030671 489 Gene3D G3DSA:3.90.820.10 223 280 0.0015 T 29-03-2018 CVS48_RS23320 26a1a8fce98b653cab84dbe93a030671 489 Gene3D G3DSA:3.90.820.10 2 49 0.075 T 29-03-2018 CVS48_RS23320 26a1a8fce98b653cab84dbe93a030671 489 Pfam PF13785 Domain of unknown function (DUF4178) 278 413 8.8E-14 T 29-03-2018 IPR025235 Domain of unknown function DUF4178 CVS48_RS23320 26a1a8fce98b653cab84dbe93a030671 489 Pfam PF13785 Domain of unknown function (DUF4178) 57 194 9.6E-21 T 29-03-2018 IPR025235 Domain of unknown function DUF4178 CVS48_RS07965 8f1771ffe4ca7b6b1c44cf8f131d3a5d 413 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 14 288 1.6E-53 T 29-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CVS48_RS07965 8f1771ffe4ca7b6b1c44cf8f131d3a5d 413 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 13 296 3.1E-90 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CVS48_RS07965 8f1771ffe4ca7b6b1c44cf8f131d3a5d 413 Gene3D G3DSA:3.90.1150.10 36 158 7.2E-4 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS07965 8f1771ffe4ca7b6b1c44cf8f131d3a5d 413 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 413 92.534 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CVS48_RS07965 8f1771ffe4ca7b6b1c44cf8f131d3a5d 413 SUPERFAMILY SSF55931 5 367 3.63E-101 T 29-03-2018 CVS48_RS15805 0455a335d0c172a456ce2a717ed1cc3c 580 SUPERFAMILY SSF143975 19 382 3.27E-113 T 29-03-2018 CVS48_RS15805 0455a335d0c172a456ce2a717ed1cc3c 580 SUPERFAMILY SSF52016 383 568 4.0E-55 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS15805 0455a335d0c172a456ce2a717ed1cc3c 580 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 130 140 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS15805 0455a335d0c172a456ce2a717ed1cc3c 580 Pfam PF00920 Dehydratase family 47 562 1.5E-172 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS15805 0455a335d0c172a456ce2a717ed1cc3c 580 Gene3D G3DSA:3.20.20.390 43 376 0.032 T 29-03-2018 CVS48_RS08290 9d0a5829e13911afc87302fa0a7726ad 95 Gene3D G3DSA:3.30.470.20 33 95 1.4E-19 T 29-03-2018 CVS48_RS08290 9d0a5829e13911afc87302fa0a7726ad 95 SUPERFAMILY SSF56059 10 92 7.07E-16 T 29-03-2018 CVS48_RS08290 9d0a5829e13911afc87302fa0a7726ad 95 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 21 91 2.9E-17 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS27615 063164af0063c285be275b6bdd4ab3f1 761 Gene3D G3DSA:3.40.50.300 495 747 8.3E-82 T 29-03-2018 CVS48_RS27615 063164af0063c285be275b6bdd4ab3f1 761 Gene3D G3DSA:1.20.1560.10 164 494 1.9E-69 T 29-03-2018 CVS48_RS27615 063164af0063c285be275b6bdd4ab3f1 761 SUPERFAMILY SSF52540 497 741 1.28E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27615 063164af0063c285be275b6bdd4ab3f1 761 Pfam PF00664 ABC transporter transmembrane region 185 458 2.2E-45 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS27615 063164af0063c285be275b6bdd4ab3f1 761 SMART SM00382 531 723 1.7E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS27615 063164af0063c285be275b6bdd4ab3f1 761 ProSitePatterns PS00211 ABC transporters family signature. 643 657 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS27615 063164af0063c285be275b6bdd4ab3f1 761 Pfam PF00005 ABC transporter 524 671 1.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS27615 063164af0063c285be275b6bdd4ab3f1 761 SUPERFAMILY SSF90123 172 486 6.02E-79 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS01925 efc6aeb8a63192acb762340957df6bdd 286 Gene3D G3DSA:3.10.129.10 12 161 2.1E-35 T 29-03-2018 CVS48_RS01925 efc6aeb8a63192acb762340957df6bdd 286 SUPERFAMILY SSF54637 177 278 3.15E-25 T 29-03-2018 IPR029069 HotDog domain CVS48_RS01925 efc6aeb8a63192acb762340957df6bdd 286 SUPERFAMILY SSF54637 10 157 1.49E-42 T 29-03-2018 IPR029069 HotDog domain CVS48_RS01925 efc6aeb8a63192acb762340957df6bdd 286 Pfam PF01575 MaoC like domain 162 263 6.8E-24 T 29-03-2018 IPR002539 MaoC-like domain CVS48_RS01925 efc6aeb8a63192acb762340957df6bdd 286 Pfam PF13452 N-terminal half of MaoC dehydratase 37 136 3.6E-9 T 29-03-2018 CVS48_RS01925 efc6aeb8a63192acb762340957df6bdd 286 Gene3D G3DSA:3.10.129.10 162 286 1.8E-23 T 29-03-2018 CVS48_RS11790 9a370d14d6554da60b83addddc0a546a 510 Gene3D G3DSA:1.10.10.10 20 96 1.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11790 9a370d14d6554da60b83addddc0a546a 510 SUPERFAMILY SSF46785 28 97 2.72E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11790 9a370d14d6554da60b83addddc0a546a 510 Gene3D G3DSA:3.40.640.10 163 410 5.9E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS11790 9a370d14d6554da60b83addddc0a546a 510 SUPERFAMILY SSF53383 146 508 8.94E-87 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS11790 9a370d14d6554da60b83addddc0a546a 510 SMART SM00345 35 94 4.2E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11790 9a370d14d6554da60b83addddc0a546a 510 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 94 7.8E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11790 9a370d14d6554da60b83addddc0a546a 510 Gene3D G3DSA:3.90.1150.10 411 510 6.6E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS11790 9a370d14d6554da60b83addddc0a546a 510 Pfam PF00155 Aminotransferase class I and II 162 431 9.2E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS20560 72211b75b6ccbb05c92040b4244b58cc 80 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 1 64 2.5E-25 T 29-03-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system CVS48_RS17435 3a54fe3334bedff8887932330eedb5b4 365 SUPERFAMILY SSF54826 5 134 1.62E-27 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS17435 3a54fe3334bedff8887932330eedb5b4 365 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 190 221 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CVS48_RS17435 3a54fe3334bedff8887932330eedb5b4 365 Pfam PF13378 Enolase C-terminal domain-like 160 355 5.6E-40 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS17435 3a54fe3334bedff8887932330eedb5b4 365 Gene3D G3DSA:3.20.20.120 135 353 3.7E-45 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS17435 3a54fe3334bedff8887932330eedb5b4 365 SUPERFAMILY SSF51604 117 360 6.93E-53 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS17435 3a54fe3334bedff8887932330eedb5b4 365 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 36 129 1.4E-13 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CVS48_RS17435 3a54fe3334bedff8887932330eedb5b4 365 Gene3D G3DSA:3.30.390.10 2 134 2.2E-33 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS17435 3a54fe3334bedff8887932330eedb5b4 365 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 104 129 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CVS48_RS17435 3a54fe3334bedff8887932330eedb5b4 365 SMART SM00922 149 241 1.6E-16 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CVS48_RS16595 935f18bc6f0e430fefe441b8ba436700 605 Gene3D G3DSA:3.40.50.300 342 602 1.9E-50 T 29-03-2018 CVS48_RS16595 935f18bc6f0e430fefe441b8ba436700 605 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS16595 935f18bc6f0e430fefe441b8ba436700 605 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 311 2.8E-29 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS16595 935f18bc6f0e430fefe441b8ba436700 605 Gene3D G3DSA:1.10.3470.10 26 318 1.5E-23 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS16595 935f18bc6f0e430fefe441b8ba436700 605 SMART SM00382 380 573 2.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16595 935f18bc6f0e430fefe441b8ba436700 605 SUPERFAMILY SSF52540 355 588 2.37E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16595 935f18bc6f0e430fefe441b8ba436700 605 Pfam PF00005 ABC transporter 371 524 1.6E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS09225 d8fae277b7a62df5a71615f00c3cee89 311 Gene3D G3DSA:3.40.50.720 2 180 1.0E-49 T 29-03-2018 CVS48_RS09225 d8fae277b7a62df5a71615f00c3cee89 311 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 180 1.1E-57 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS09225 d8fae277b7a62df5a71615f00c3cee89 311 Gene3D G3DSA:1.10.1040.10 182 286 8.0E-28 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS09225 d8fae277b7a62df5a71615f00c3cee89 311 SUPERFAMILY SSF51735 5 179 5.02E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09225 d8fae277b7a62df5a71615f00c3cee89 311 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 183 281 4.5E-23 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS09225 d8fae277b7a62df5a71615f00c3cee89 311 SUPERFAMILY SSF48179 182 287 8.5E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS09225 d8fae277b7a62df5a71615f00c3cee89 311 PIRSF PIRSF000105 1 306 1.1E-90 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CVS48_RS03990 3adfe2240c4be727dc9ab8af9f5659d4 292 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 13 284 21.575 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CVS48_RS03990 3adfe2240c4be727dc9ab8af9f5659d4 292 SUPERFAMILY SSF53613 17 285 7.75E-63 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS03990 3adfe2240c4be727dc9ab8af9f5659d4 292 Gene3D G3DSA:3.40.1190.20 4 288 2.9E-47 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS03990 3adfe2240c4be727dc9ab8af9f5659d4 292 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 22 278 5.7E-59 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CVS48_RS03990 3adfe2240c4be727dc9ab8af9f5659d4 292 Pfam PF01256 Carbohydrate kinase 36 263 1.6E-52 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CVS48_RS03990 3adfe2240c4be727dc9ab8af9f5659d4 292 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 222 232 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CVS48_RS07810 4e8a9c446020c461d1505189659df659 565 Pfam PF00005 ABC transporter 358 507 1.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07810 4e8a9c446020c461d1505189659df659 565 SMART SM00382 367 553 8.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS07810 4e8a9c446020c461d1505189659df659 565 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS07810 4e8a9c446020c461d1505189659df659 565 SUPERFAMILY SSF52540 330 562 4.83E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07810 4e8a9c446020c461d1505189659df659 565 Pfam PF00664 ABC transporter transmembrane region 29 271 9.0E-14 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS07810 4e8a9c446020c461d1505189659df659 565 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 7 536 5.3E-124 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CVS48_RS07810 4e8a9c446020c461d1505189659df659 565 Gene3D G3DSA:3.40.50.300 326 565 1.5E-53 T 29-03-2018 CVS48_RS07810 4e8a9c446020c461d1505189659df659 565 Gene3D G3DSA:1.20.1560.10 1 325 2.1E-32 T 29-03-2018 CVS48_RS07810 4e8a9c446020c461d1505189659df659 565 SUPERFAMILY SSF90123 7 325 7.59E-39 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 2.8E-15 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 2.8E-15 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.8E-15 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.8E-15 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 Gene3D G3DSA:1.10.287.990 37 106 1.1E-15 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 Gene3D G3DSA:3.30.390.30 346 474 2.0E-20 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 SUPERFAMILY SSF55424 346 460 1.48E-21 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 2.9E-40 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.9E-40 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 2.9E-40 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 2.9E-40 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 2.9E-40 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 2.9E-40 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 2.9E-40 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 2.9E-40 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 2.9E-40 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 453 1.3E-13 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 326 2.1E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 PIRSF PIRSF000350 2 459 3.2E-54 T 29-03-2018 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 Gene3D G3DSA:3.50.50.60 240 336 1.9E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 SUPERFAMILY SSF51905 114 191 1.47E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 SUPERFAMILY SSF51905 1 56 1.47E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 SUPERFAMILY SSF51905 219 361 1.47E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19750 b8b5815584007468d92b52ecf2a4d227 478 Gene3D G3DSA:3.50.50.60 116 239 3.5E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 SUPERFAMILY SSF118215 19 412 1.24E-117 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 PRINTS PR00173 Glutamate-aspartate symporter signature 84 109 1.8E-29 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 PRINTS PR00173 Glutamate-aspartate symporter signature 54 74 1.8E-29 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 PRINTS PR00173 Glutamate-aspartate symporter signature 13 33 1.8E-29 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 PRINTS PR00173 Glutamate-aspartate symporter signature 155 177 1.8E-29 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 PRINTS PR00173 Glutamate-aspartate symporter signature 337 356 1.8E-29 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 PRINTS PR00173 Glutamate-aspartate symporter signature 302 328 1.8E-29 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 Gene3D G3DSA:1.10.3860.10 8 418 3.4E-115 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 12 438 38.188 T 29-03-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 305 328 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 46 61 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CVS48_RS14315 2c9e78799126257a2fb8754ca09e7739 451 Pfam PF00375 Sodium:dicarboxylate symporter family 19 411 3.7E-107 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CVS48_RS11645 3a4f6c1e438e542db68113d14f690d5e 230 Gene3D G3DSA:3.30.450.40 144 214 4.6E-11 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS11645 3a4f6c1e438e542db68113d14f690d5e 230 Gene3D G3DSA:1.10.10.10 1 66 9.0E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11645 3a4f6c1e438e542db68113d14f690d5e 230 Gene3D G3DSA:3.30.450.40 67 143 3.5E-12 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS11645 3a4f6c1e438e542db68113d14f690d5e 230 SUPERFAMILY SSF46785 2 71 4.99E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11645 3a4f6c1e438e542db68113d14f690d5e 230 Pfam PF09339 IclR helix-turn-helix domain 2 48 7.5E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS11645 3a4f6c1e438e542db68113d14f690d5e 230 Pfam PF01614 Bacterial transcriptional regulator 151 208 7.4E-8 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS11645 3a4f6c1e438e542db68113d14f690d5e 230 SUPERFAMILY SSF55781 56 209 5.89E-26 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS11645 3a4f6c1e438e542db68113d14f690d5e 230 SMART SM00346 1 88 1.2E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS14860 4c0367ce2728b1f24336da07d6c20894 338 Gene3D G3DSA:3.20.20.70 5 245 5.3E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS14860 4c0367ce2728b1f24336da07d6c20894 338 SUPERFAMILY SSF51395 7 301 5.04E-64 T 29-03-2018 CVS48_RS14860 4c0367ce2728b1f24336da07d6c20894 338 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 2 322 46.197 T 29-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 CVS48_RS14860 4c0367ce2728b1f24336da07d6c20894 338 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 89 107 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CVS48_RS14860 4c0367ce2728b1f24336da07d6c20894 338 Pfam PF01207 Dihydrouridine synthase (Dus) 10 301 8.3E-72 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CVS48_RS14860 4c0367ce2728b1f24336da07d6c20894 338 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 7 318 6.9E-121 T 29-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 478 3.4E-158 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 Gene3D G3DSA:3.20.20.60 171 326 8.9E-55 T 29-03-2018 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 362 477 1.0E-25 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 Gene3D G3DSA:2.40.33.10 83 170 5.5E-23 T 29-03-2018 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 ProSitePatterns PS00110 Pyruvate kinase active site signature. 217 229 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 SUPERFAMILY SSF52935 328 479 9.92E-36 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 Gene3D G3DSA:3.40.1380.20 327 480 5.4E-39 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 SUPERFAMILY SSF51621 170 344 1.81E-90 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 SUPERFAMILY SSF51621 3 78 1.81E-90 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 Gene3D G3DSA:3.20.20.60 2 82 1.0E-15 T 29-03-2018 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 PRINTS PR01050 Pyruvate kinase family signature 274 298 1.8E-50 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 PRINTS PR01050 Pyruvate kinase family signature 189 203 1.8E-50 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 PRINTS PR01050 Pyruvate kinase family signature 62 78 1.8E-50 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 PRINTS PR01050 Pyruvate kinase family signature 249 273 1.8E-50 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 PRINTS PR01050 Pyruvate kinase family signature 318 334 1.8E-50 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 PRINTS PR01050 Pyruvate kinase family signature 299 317 1.8E-50 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 PRINTS PR01050 Pyruvate kinase family signature 222 248 1.8E-50 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 Pfam PF00224 Pyruvate kinase, barrel domain 5 343 2.6E-120 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CVS48_RS01995 bc5cb25532251e81fdb3c356f8e5f2f9 480 SUPERFAMILY SSF50800 73 168 4.01E-23 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Gene3D G3DSA:2.60.40.10 905 1063 0.0059 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 808 951 8.3E-15 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Pfam PF00207 Alpha-2-macroglobulin family 1021 1102 5.3E-11 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Pfam PF07678 A-macroglobulin complement component 1274 1350 3.2E-7 T 29-03-2018 IPR011626 Alpha-macroglobulin complement component GO:0005615 CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 PIRSF PIRSF038980 1 1725 0.0 T 29-03-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Gene3D G3DSA:2.60.40.10 353 850 1.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 ProSitePatterns PS00477 Alpha-2-macroglobulin family thiolester region signature. 1226 1234 - T 29-03-2018 IPR019742 Alpha-2-macroglobulin, conserved site CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 347 440 2.5E-20 T 29-03-2018 CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Pfam PF10569 Alpha-macro-globulin thiol-ester bond-forming region 1220 1242 3.2E-5 T 29-03-2018 IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Gene3D G3DSA:1.50.10.20 1215 1512 5.6E-28 T 29-03-2018 CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 SMART SM01359 807 951 1.3E-36 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 SUPERFAMILY SSF48239 1217 1503 1.05E-40 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Pfam PF01835 MG2 domain 447 544 5.2E-16 T 29-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 SMART SM01360 1013 1102 4.1E-27 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 CVS48_RS22410 fd6d8d3fcd1fb558717918667b43fbb2 1730 Gene3D G3DSA:2.60.40.10 1064 1167 3.7E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 444 4.8E-201 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 SUPERFAMILY SSF52540 5 439 2.16E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 444 42.362 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 Pfam PF07724 AAA domain (Cdc48 subfamily) 190 330 4.8E-39 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 Gene3D G3DSA:3.40.50.300 3 333 8.3E-49 T 29-03-2018 CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 SMART SM01086 336 432 5.3E-18 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 105 1.3E-6 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 Gene3D G3DSA:1.10.8.60 336 432 2.9E-27 T 29-03-2018 CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 SMART SM00382 51 333 3.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS07240 c1dc8ca8e59e09cabe53847d7b91469b 444 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 336 406 8.6E-6 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS26010 802c89fb6f905879912374f37232fc50 426 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 332 353 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CVS48_RS26010 802c89fb6f905879912374f37232fc50 426 Pfam PF00171 Aldehyde dehydrogenase family 318 381 1.5E-7 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS26010 802c89fb6f905879912374f37232fc50 426 Pfam PF00171 Aldehyde dehydrogenase family 20 289 1.1E-14 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS26010 802c89fb6f905879912374f37232fc50 426 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 14 425 41.426 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CVS48_RS26010 802c89fb6f905879912374f37232fc50 426 Gene3D G3DSA:3.40.605.10 4 248 4.7E-43 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS26010 802c89fb6f905879912374f37232fc50 426 Gene3D G3DSA:3.40.605.10 249 426 2.3E-38 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS26010 802c89fb6f905879912374f37232fc50 426 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 22 415 3.8E-142 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CVS48_RS26010 802c89fb6f905879912374f37232fc50 426 SUPERFAMILY SSF53720 18 425 7.98E-116 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS26010 802c89fb6f905879912374f37232fc50 426 PIRSF PIRSF000151 7 426 1.5E-171 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CVS48_RS07125 43c64bac1f954fae482bbd6d5bdeb2cd 413 Pfam PF13579 Glycosyl transferase 4-like domain 16 200 1.5E-21 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS07125 43c64bac1f954fae482bbd6d5bdeb2cd 413 Gene3D G3DSA:3.40.50.2000 1 217 5.4E-26 T 29-03-2018 CVS48_RS07125 43c64bac1f954fae482bbd6d5bdeb2cd 413 SUPERFAMILY SSF53756 2 404 4.71E-47 T 29-03-2018 CVS48_RS07125 43c64bac1f954fae482bbd6d5bdeb2cd 413 Pfam PF13692 Glycosyl transferases group 1 230 367 3.2E-12 T 29-03-2018 CVS48_RS07125 43c64bac1f954fae482bbd6d5bdeb2cd 413 Gene3D G3DSA:3.40.50.2000 218 391 7.3E-23 T 29-03-2018 CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 Gene3D G3DSA:3.40.190.10 105 194 3.0E-16 T 29-03-2018 CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 SUPERFAMILY SSF46785 18 99 1.26E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 57 68 1.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 47 1.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 57 1.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 79 1.4E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 Gene3D G3DSA:1.10.10.10 14 102 9.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 Gene3D G3DSA:3.40.190.10 195 284 1.0E-18 T 29-03-2018 CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 SUPERFAMILY SSF53850 106 316 4.96E-36 T 29-03-2018 CVS48_RS17715 600c62cf051f2592353b387b71fc0498 323 Pfam PF03466 LysR substrate binding domain 105 300 1.7E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS27420 0900b36dff087eac87c9d44a17b6c5ca 608 Pfam PF00155 Aminotransferase class I and II 204 531 5.9E-26 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS27420 0900b36dff087eac87c9d44a17b6c5ca 608 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 28 548 1.0E-228 T 29-03-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CVS48_RS27420 0900b36dff087eac87c9d44a17b6c5ca 608 Gene3D G3DSA:3.40.640.10 172 385 6.2E-26 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS27420 0900b36dff087eac87c9d44a17b6c5ca 608 SUPERFAMILY SSF53383 127 359 5.84E-48 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS27420 0900b36dff087eac87c9d44a17b6c5ca 608 SUPERFAMILY SSF53383 396 530 5.84E-48 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS27420 0900b36dff087eac87c9d44a17b6c5ca 608 Gene3D G3DSA:3.90.1150.10 387 546 6.2E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS19535 4d1961ad989a57f6c482bcf9ed63b4bf 498 Gene3D G3DSA:3.30.1730.10 20 182 1.8E-56 T 29-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CVS48_RS19535 4d1961ad989a57f6c482bcf9ed63b4bf 498 SUPERFAMILY SSF53167 23 498 1.96E-152 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CVS48_RS19535 4d1961ad989a57f6c482bcf9ed63b4bf 498 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 26 498 8.2E-210 T 29-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CVS48_RS19535 4d1961ad989a57f6c482bcf9ed63b4bf 498 Pfam PF01048 Phosphorylase superfamily 285 443 4.2E-13 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CVS48_RS19535 4d1961ad989a57f6c482bcf9ed63b4bf 498 Hamap MF_01932 AMP nucleosidase [amn]. 17 498 61.772 T 29-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CVS48_RS19535 4d1961ad989a57f6c482bcf9ed63b4bf 498 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 26 181 2.5E-53 T 29-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CVS48_RS19535 4d1961ad989a57f6c482bcf9ed63b4bf 498 Gene3D G3DSA:3.40.50.1580 188 480 1.1E-63 T 29-03-2018 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 SUPERFAMILY SSF88659 654 755 6.35E-27 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 PRINTS PR00046 Major sigma-70 factor signature 732 743 7.9E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 PRINTS PR00046 Major sigma-70 factor signature 572 580 7.9E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 PRINTS PR00046 Major sigma-70 factor signature 717 732 7.9E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 PRINTS PR00046 Major sigma-70 factor signature 548 561 7.9E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 PRINTS PR00046 Major sigma-70 factor signature 696 708 7.9E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 156 757 41.881 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 520 745 3.3E-39 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Pfam PF04545 Sigma-70, region 4 692 745 7.7E-19 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 717 743 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 548 561 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 SUPERFAMILY SSF88659 597 670 2.04E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Pfam PF04546 Sigma-70, non-essential region 293 493 1.3E-61 T 29-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 520 756 1.8E-118 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Gene3D G3DSA:1.10.10.10 594 644 6.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Pfam PF00140 Sigma-70 factor, region 1.2 252 284 4.7E-14 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Pfam PF04542 Sigma-70 region 2 526 593 8.6E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Gene3D G3DSA:1.10.10.10 686 757 2.6E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 SUPERFAMILY SSF88946 269 591 2.04E-96 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Gene3D G3DSA:1.10.601.10 1 268 1.4E-16 T 29-03-2018 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Gene3D G3DSA:1.10.601.10 269 593 1.3E-99 T 29-03-2018 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Pfam PF03979 Sigma-70 factor, region 1.1 156 235 1.2E-28 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CVS48_RS14770 7057c31c22202ea8f731c97a4986dbc5 759 Pfam PF04539 Sigma-70 region 3 603 678 3.1E-24 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 PIRSF PIRSF001365 7 301 1.3E-95 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 297 66.343 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 SUPERFAMILY SSF51569 11 299 1.36E-103 T 29-03-2018 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 Gene3D G3DSA:3.20.20.70 2 301 4.0E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 SMART SM01130 11 299 2.0E-140 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 143 173 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 1.6E-35 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 1.6E-35 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 1.6E-35 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 1.6E-35 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 15 297 1.5E-107 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 Pfam PF00701 Dihydrodipicolinate synthetase family 11 297 8.4E-103 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS24675 2f8402c8ba365e7314a9db69a58a2ac0 301 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 48 65 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 SUPERFAMILY SSF50156 219 284 1.26E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 Gene3D G3DSA:2.30.42.10 220 304 9.0E-16 T 29-03-2018 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 Pfam PF13180 PDZ domain 211 283 1.6E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 Pfam PF13180 PDZ domain 123 169 4.3E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 Gene3D G3DSA:2.30.42.10 23 195 3.3E-12 T 29-03-2018 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 SUPERFAMILY SSF50156 84 180 7.76E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 SMART SM00228 208 275 0.0012 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 SMART SM00228 112 184 1.1E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 Pfam PF02163 Peptidase family M50 7 428 2.9E-76 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CVS48_RS17155 312ce2fd9d1597d3018b0f21c9827fc0 443 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 442 3.8E-110 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CVS48_RS16855 af83fba45952687e85fc1762e3c144f7 238 SMART SM00858 114 176 2.1E-12 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS16855 af83fba45952687e85fc1762e3c144f7 238 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 102 237 2.6E-38 T 29-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal CVS48_RS16855 af83fba45952687e85fc1762e3c144f7 238 Gene3D G3DSA:3.90.1210.10 115 177 2.9E-14 T 29-03-2018 CVS48_RS16855 af83fba45952687e85fc1762e3c144f7 238 Pfam PF13144 Chaperone for flagella basal body P-ring formation 39 236 2.3E-44 T 29-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal CVS48_RS18930 814a377439cbfa93062dd85d529162e9 152 Pfam PF00583 Acetyltransferase (GNAT) family 36 135 2.9E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS18930 814a377439cbfa93062dd85d529162e9 152 Gene3D G3DSA:3.40.630.30 9 141 7.9E-17 T 29-03-2018 CVS48_RS18930 814a377439cbfa93062dd85d529162e9 152 SUPERFAMILY SSF55729 15 138 4.63E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR00701 60kDa inner membrane protein signature 339 359 6.7E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR00701 60kDa inner membrane protein signature 2 23 6.7E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR00701 60kDa inner membrane protein signature 89 110 6.7E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR00701 60kDa inner membrane protein signature 513 536 6.7E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR00701 60kDa inner membrane protein signature 177 197 6.7E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR00701 60kDa inner membrane protein signature 477 499 6.7E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR00701 60kDa inner membrane protein signature 430 453 6.7E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR00701 60kDa inner membrane protein signature 266 281 6.7E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR00701 60kDa inner membrane protein signature 231 249 6.7E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 Pfam PF02096 60Kd inner membrane protein 369 546 5.0E-57 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 549 24.197 T 29-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 368 547 1.2E-67 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR01900 YidC translocation/secretion protein signature 483 498 5.5E-21 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR01900 YidC translocation/secretion protein signature 354 370 5.5E-21 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 PRINTS PR01900 YidC translocation/secretion protein signature 502 526 5.5E-21 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 Pfam PF14849 YidC periplasmic domain 84 358 2.1E-80 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal CVS48_RS06055 fc99e77173e5150b48202e3c30c60070 559 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 367 3.7E-111 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal CVS48_RS16505 49a79315ee8377d8518ae9156965f97f 401 Gene3D G3DSA:3.40.50.2300 16 166 7.8E-23 T 29-03-2018 CVS48_RS16505 49a79315ee8377d8518ae9156965f97f 401 Gene3D G3DSA:3.40.50.2300 167 298 7.8E-21 T 29-03-2018 CVS48_RS16505 49a79315ee8377d8518ae9156965f97f 401 Pfam PF13458 Periplasmic binding protein 31 374 6.2E-50 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS16505 49a79315ee8377d8518ae9156965f97f 401 Gene3D G3DSA:3.40.50.2300 299 373 0.011 T 29-03-2018 CVS48_RS16505 49a79315ee8377d8518ae9156965f97f 401 SUPERFAMILY SSF53822 31 397 1.95E-69 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS16505 49a79315ee8377d8518ae9156965f97f 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 54 70 1.3E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS16505 49a79315ee8377d8518ae9156965f97f 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 1.3E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS09675 e6568be0ba645bc910b543015c45443c 438 Pfam PF07690 Major Facilitator Superfamily 33 396 3.0E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS09675 e6568be0ba645bc910b543015c45443c 438 SUPERFAMILY SSF103473 9 437 2.35E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS09675 e6568be0ba645bc910b543015c45443c 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 310 325 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS09675 e6568be0ba645bc910b543015c45443c 438 Gene3D G3DSA:1.20.1250.20 236 438 3.9E-22 T 29-03-2018 CVS48_RS09675 e6568be0ba645bc910b543015c45443c 438 Gene3D G3DSA:1.20.1250.20 11 231 8.3E-36 T 29-03-2018 CVS48_RS19150 88a872bfea249964934ff38252c323a2 238 SMART SM00448 1 114 1.9E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19150 88a872bfea249964934ff38252c323a2 238 Gene3D G3DSA:1.10.10.10 128 232 6.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19150 88a872bfea249964934ff38252c323a2 238 SUPERFAMILY SSF52172 2 125 2.13E-26 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS19150 88a872bfea249964934ff38252c323a2 238 Pfam PF00072 Response regulator receiver domain 3 112 2.3E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19150 88a872bfea249964934ff38252c323a2 238 Gene3D G3DSA:3.40.50.2300 1 127 8.8E-23 T 29-03-2018 CVS48_RS19150 88a872bfea249964934ff38252c323a2 238 SUPERFAMILY SSF46894 135 225 9.35E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS19150 88a872bfea249964934ff38252c323a2 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 225 1.0E-13 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS19150 88a872bfea249964934ff38252c323a2 238 SMART SM00862 150 226 2.6E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 SUPERFAMILY SSF51735 4 212 5.2E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 Pfam PF00106 short chain dehydrogenase 5 186 5.6E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 188 0.0097 T 29-03-2018 CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 Gene3D G3DSA:3.40.50.720 3 268 2.8E-58 T 29-03-2018 CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.1E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.1E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12350 9ce5bbcf376df1d87a154460496fc6b2 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.1E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13940 af4ea4ae7673315753729d04154ed2e3 210 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 77 2.6E-12 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS13940 af4ea4ae7673315753729d04154ed2e3 210 SUPERFAMILY SSF47616 85 200 1.28E-20 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS13940 af4ea4ae7673315753729d04154ed2e3 210 Pfam PF14497 Glutathione S-transferase, C-terminal domain 126 196 3.8E-8 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS13940 af4ea4ae7673315753729d04154ed2e3 210 SUPERFAMILY SSF52833 1 83 1.22E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS13940 af4ea4ae7673315753729d04154ed2e3 210 Gene3D G3DSA:1.20.1050.10 100 205 8.5E-18 T 29-03-2018 CVS48_RS13940 af4ea4ae7673315753729d04154ed2e3 210 Gene3D G3DSA:3.40.30.10 1 99 3.6E-22 T 29-03-2018 CVS48_RS04660 a4ca537486ac89ac84f11b57a8f82329 277 Gene3D G3DSA:2.40.50.40 168 238 1.5E-6 T 29-03-2018 CVS48_RS04660 a4ca537486ac89ac84f11b57a8f82329 277 SMART SM00065 7 161 0.0055 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS04660 a4ca537486ac89ac84f11b57a8f82329 277 Pfam PF04397 LytTr DNA-binding domain 182 275 4.6E-11 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CVS48_RS04660 a4ca537486ac89ac84f11b57a8f82329 277 Pfam PF01590 GAF domain 9 150 5.2E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS04660 a4ca537486ac89ac84f11b57a8f82329 277 SMART SM00850 177 276 1.6E-11 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CVS48_RS04660 a4ca537486ac89ac84f11b57a8f82329 277 SUPERFAMILY SSF55781 9 150 4.17E-16 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS04660 a4ca537486ac89ac84f11b57a8f82329 277 Gene3D G3DSA:3.30.450.40 5 150 6.6E-15 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS25245 3ac94e293cb20a75e5dae86d5b594b5b 539 Gene3D G3DSA:3.30.300.30 427 532 3.5E-24 T 29-03-2018 CVS48_RS25245 3ac94e293cb20a75e5dae86d5b594b5b 539 Pfam PF00501 AMP-binding enzyme 14 432 1.4E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS25245 3ac94e293cb20a75e5dae86d5b594b5b 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 441 510 1.6E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS25245 3ac94e293cb20a75e5dae86d5b594b5b 539 Gene3D G3DSA:3.40.50.980 1 191 8.7E-39 T 29-03-2018 CVS48_RS25245 3ac94e293cb20a75e5dae86d5b594b5b 539 Gene3D G3DSA:3.40.50.980 192 348 9.6E-39 T 29-03-2018 CVS48_RS25245 3ac94e293cb20a75e5dae86d5b594b5b 539 Gene3D G3DSA:2.30.38.10 350 426 1.8E-22 T 29-03-2018 CVS48_RS25245 3ac94e293cb20a75e5dae86d5b594b5b 539 SUPERFAMILY SSF56801 4 530 1.96E-137 T 29-03-2018 CVS48_RS25245 3ac94e293cb20a75e5dae86d5b594b5b 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 151 3.0E-25 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 Gene3D G3DSA:3.40.50.720 189 310 3.5E-24 T 29-03-2018 CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 1.3E-221 T 29-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 Gene3D G3DSA:3.90.180.10 1 188 1.7E-60 T 29-03-2018 CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 SUPERFAMILY SSF50129 1 186 5.72E-73 T 29-03-2018 IPR011032 GroES-like CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 SUPERFAMILY SSF50129 318 369 3.25E-12 T 29-03-2018 IPR011032 GroES-like CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 SUPERFAMILY SSF51735 160 334 7.89E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 Pfam PF00107 Zinc-binding dehydrogenase 197 330 6.5E-23 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS04490 54b2e9158aa35c7f550290163a8b6246 369 SMART SM00829 10 367 9.8E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS23520 25d298a76353ab9200120fe3ca49fe55 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.2E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23520 25d298a76353ab9200120fe3ca49fe55 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.2E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23520 25d298a76353ab9200120fe3ca49fe55 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.2E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23520 25d298a76353ab9200120fe3ca49fe55 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.2E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23520 25d298a76353ab9200120fe3ca49fe55 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.2E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23520 25d298a76353ab9200120fe3ca49fe55 295 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 252 8.4E-48 T 29-03-2018 CVS48_RS23520 25d298a76353ab9200120fe3ca49fe55 295 SUPERFAMILY SSF51735 9 254 1.9E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23520 25d298a76353ab9200120fe3ca49fe55 295 Gene3D G3DSA:3.40.50.720 52 264 3.9E-50 T 29-03-2018 CVS48_RS23520 25d298a76353ab9200120fe3ca49fe55 295 Gene3D G3DSA:3.40.50.10090 3 51 4.0E-9 T 29-03-2018 CVS48_RS14835 f6a78620090ac0d946220decfd07c0ea 567 Pfam PF00437 Type II/IV secretion system protein 211 487 5.2E-82 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS14835 f6a78620090ac0d946220decfd07c0ea 567 SUPERFAMILY SSF52540 196 525 2.99E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14835 f6a78620090ac0d946220decfd07c0ea 567 SMART SM00240 21 71 5.8E-6 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CVS48_RS14835 f6a78620090ac0d946220decfd07c0ea 567 SUPERFAMILY SSF49879 14 103 7.87E-18 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CVS48_RS14835 f6a78620090ac0d946220decfd07c0ea 567 Gene3D G3DSA:3.40.50.300 308 523 2.4E-18 T 29-03-2018 CVS48_RS14835 f6a78620090ac0d946220decfd07c0ea 567 Pfam PF00498 FHA domain 23 84 3.7E-10 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CVS48_RS14835 f6a78620090ac0d946220decfd07c0ea 567 Gene3D G3DSA:3.30.450.90 206 307 1.7E-35 T 29-03-2018 CVS48_RS14835 f6a78620090ac0d946220decfd07c0ea 567 Gene3D G3DSA:2.60.200.20 6 115 3.6E-13 T 29-03-2018 CVS48_RS02475 002ed64ca808a8eae4ba78a5c29ecd2e 397 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 28 387 1.6E-121 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CVS48_RS02475 002ed64ca808a8eae4ba78a5c29ecd2e 397 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 23 396 38.928 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CVS48_RS02475 002ed64ca808a8eae4ba78a5c29ecd2e 397 Pfam PF01098 Cell cycle protein 30 389 2.7E-99 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CVS48_RS02575 7e04a6f81e6cc95643c89e9eb9a17fb3 184 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 9 168 33.824 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS02575 7e04a6f81e6cc95643c89e9eb9a17fb3 184 Pfam PF01625 Peptide methionine sulfoxide reductase 12 164 1.7E-57 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS02575 7e04a6f81e6cc95643c89e9eb9a17fb3 184 SUPERFAMILY SSF55068 6 175 2.35E-68 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS02575 7e04a6f81e6cc95643c89e9eb9a17fb3 184 Gene3D G3DSA:3.30.1060.10 8 180 3.4E-64 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS02575 7e04a6f81e6cc95643c89e9eb9a17fb3 184 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 11 163 9.5E-52 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS28450 e8cc0257b6d4fb1194ec675edd01c96f 408 Pfam PF06850 PHB de-polymerase C-terminus 206 406 4.0E-95 T 29-03-2018 IPR009656 PHB de-polymerase, C-terminal CVS48_RS28450 e8cc0257b6d4fb1194ec675edd01c96f 408 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 406 6.7E-189 T 29-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase CVS48_RS28450 e8cc0257b6d4fb1194ec675edd01c96f 408 Gene3D G3DSA:3.40.50.1820 67 407 8.0E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS28450 e8cc0257b6d4fb1194ec675edd01c96f 408 PIRSF PIRSF020818 1 408 1.8E-201 T 29-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase CVS48_RS28450 e8cc0257b6d4fb1194ec675edd01c96f 408 SUPERFAMILY SSF53474 98 405 4.55E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS08790 06584eb79d835f9cfe3ada927e2bf311 212 Gene3D G3DSA:3.40.225.10 3 197 9.3E-51 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS08790 06584eb79d835f9cfe3ada927e2bf311 212 SMART SM01007 9 187 1.6E-49 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS08790 06584eb79d835f9cfe3ada927e2bf311 212 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 186 3.5E-41 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS08790 06584eb79d835f9cfe3ada927e2bf311 212 SUPERFAMILY SSF53639 4 209 6.08E-54 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 Gene3D G3DSA:3.30.230.10 235 406 2.9E-61 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 Gene3D G3DSA:3.30.565.10 11 234 1.8E-72 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 Pfam PF00204 DNA gyrase B 231 404 2.7E-58 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 744 804 1.4E-29 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 Gene3D G3DSA:3.40.50.670 415 812 2.8E-104 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 SMART SM00433 44 808 4.6E-263 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 SUPERFAMILY SSF55874 14 226 2.1E-68 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 SMART SM00387 40 186 1.0E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 ProSitePatterns PS00177 DNA topoisomerase II signature. 436 444 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR00418 DNA topoisomerase II family signature 434 448 4.4E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR00418 DNA topoisomerase II family signature 747 763 4.4E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR00418 DNA topoisomerase II family signature 538 550 4.4E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR00418 DNA topoisomerase II family signature 282 295 4.4E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR00418 DNA topoisomerase II family signature 44 59 4.4E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR00418 DNA topoisomerase II family signature 518 535 4.4E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR00418 DNA topoisomerase II family signature 124 138 4.4E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR00418 DNA topoisomerase II family signature 500 516 4.4E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR00418 DNA topoisomerase II family signature 79 92 4.4E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 11 815 99.549 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 SUPERFAMILY SSF56719 408 573 7.06E-84 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 SUPERFAMILY SSF56719 741 805 7.06E-84 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 14 814 2.3E-294 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 Pfam PF01751 Toprim domain 433 544 1.4E-17 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 326 342 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 768 780 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 256 274 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 14 24 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 230 252 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 206 219 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 784 800 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 191 206 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 484 493 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 374 388 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 PRINTS PR01159 DNA gyrase subunit B signature 388 408 3.9E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 181 5.2E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS06025 87d68d91281a51fa83c6a9f4e98e8b88 815 SUPERFAMILY SSF54211 231 406 5.5E-56 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS20025 6486cb907934410ad0fac74a26f224cd 362 SUPERFAMILY SSF52540 23 248 3.91E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20025 6486cb907934410ad0fac74a26f224cd 362 Gene3D G3DSA:2.40.50.100 245 295 1.1E-5 T 29-03-2018 CVS48_RS20025 6486cb907934410ad0fac74a26f224cd 362 Pfam PF00005 ABC transporter 27 167 2.2E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS20025 6486cb907934410ad0fac74a26f224cd 362 SUPERFAMILY SSF50331 242 355 8.75E-17 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS20025 6486cb907934410ad0fac74a26f224cd 362 SMART SM00382 33 217 2.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS20025 6486cb907934410ad0fac74a26f224cd 362 Gene3D G3DSA:2.40.50.140 296 348 3.1E-8 T 29-03-2018 CVS48_RS20025 6486cb907934410ad0fac74a26f224cd 362 Pfam PF08402 TOBE domain 283 347 2.2E-5 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS20025 6486cb907934410ad0fac74a26f224cd 362 Gene3D G3DSA:3.40.50.300 2 240 1.1E-53 T 29-03-2018 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 Gene3D G3DSA:2.102.10.10 41 147 1.2E-26 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 28 53 2.6E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 58 73 2.6E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 79 99 2.6E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 2.6E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 141 167 2.6E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 SUPERFAMILY SSF55961 157 369 9.42E-34 T 29-03-2018 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 Pfam PF00355 Rieske [2Fe-2S] domain 44 131 4.1E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 SUPERFAMILY SSF50022 14 157 5.37E-47 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 Gene3D G3DSA:3.90.380.10 148 377 2.5E-40 T 29-03-2018 CVS48_RS20825 fe324a5022081876bd93bb5c0b516111 388 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 180 368 1.2E-20 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 Pfam PF12680 SnoaL-like domain 16 114 6.8E-7 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 SUPERFAMILY SSF54427 9 116 8.37E-13 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 Gene3D G3DSA:3.50.50.60 165 318 5.1E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 SUPERFAMILY SSF51905 159 363 4.49E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 SUPERFAMILY SSF51905 453 566 4.49E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 Gene3D G3DSA:3.50.50.60 319 503 2.2E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 169 365 1.1E-21 T 29-03-2018 CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 Gene3D G3DSA:3.10.450.50 1 141 2.2E-12 T 29-03-2018 CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 189 4.4E-6 T 29-03-2018 CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 332 357 4.4E-6 T 29-03-2018 CVS48_RS10155 a09c48e54acbdbb9bce2d26364bbf339 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 291 300 4.4E-6 T 29-03-2018 CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 8 217 8.2E-61 T 29-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 192 2.5E-30 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 4.0E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 4.0E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 105 118 4.0E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 SUPERFAMILY SSF56784 1 221 4.94E-54 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 80 192 1.2E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 186 2.0E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 Gene3D G3DSA:1.10.150.240 19 97 1.5E-20 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CVS48_RS04230 5be78393e29e12b2f4e1622f4956ef4f 235 Gene3D G3DSA:3.40.50.1000 98 227 6.3E-32 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS15770 e73dd0c1d8ac4a412864d59b5a605844 52 TIGRFAM TIGR02973 nitrate_rd_NapE: periplasmic nitrate reductase, NapE protein 10 51 1.1E-24 T 29-03-2018 IPR004448 Nitrate reductas, NapE, periplasmic CVS48_RS15770 e73dd0c1d8ac4a412864d59b5a605844 52 Pfam PF06796 Periplasmic nitrate reductase protein NapE 3 51 3.0E-23 T 29-03-2018 IPR010649 Nitrate/trimethylamine N-oxide reductase NapE/TorE CVS48_RS01885 3731d854f81a03049ed152708d500e10 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 58 115 3.9E-18 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CVS48_RS01885 3731d854f81a03049ed152708d500e10 134 Gene3D G3DSA:2.40.50.140 59 119 2.9E-15 T 29-03-2018 CVS48_RS01885 3731d854f81a03049ed152708d500e10 134 SUPERFAMILY SSF50249 13 122 1.22E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS01885 3731d854f81a03049ed152708d500e10 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 19 54 1.2E-13 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CVS48_RS18620 cd9b5cd9406d20136e0a9fb3772a9bf7 255 SUPERFAMILY SSF52218 16 235 1.8E-64 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS18620 cd9b5cd9406d20136e0a9fb3772a9bf7 255 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 17 234 8.2E-126 T 29-03-2018 IPR014063 Arsenate resistance ArsH CVS48_RS18620 cd9b5cd9406d20136e0a9fb3772a9bf7 255 Pfam PF03358 NADPH-dependent FMN reductase 43 186 1.9E-26 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CVS48_RS18620 cd9b5cd9406d20136e0a9fb3772a9bf7 255 Gene3D G3DSA:3.40.50.360 32 234 2.4E-47 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS15860 29ed04666de3c19192c75b5850972bd7 573 Pfam PF13193 AMP-binding enzyme C-terminal domain 473 545 2.0E-5 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS15860 29ed04666de3c19192c75b5850972bd7 573 Pfam PF00501 AMP-binding enzyme 15 460 3.7E-58 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS15860 29ed04666de3c19192c75b5850972bd7 573 SUPERFAMILY SSF56801 186 563 1.96E-96 T 29-03-2018 CVS48_RS15860 29ed04666de3c19192c75b5850972bd7 573 SUPERFAMILY SSF56801 6 143 1.96E-96 T 29-03-2018 CVS48_RS15860 29ed04666de3c19192c75b5850972bd7 573 Gene3D G3DSA:2.30.38.10 373 457 5.6E-16 T 29-03-2018 CVS48_RS15860 29ed04666de3c19192c75b5850972bd7 573 Gene3D G3DSA:3.30.300.30 460 567 6.0E-15 T 29-03-2018 CVS48_RS15860 29ed04666de3c19192c75b5850972bd7 573 Gene3D G3DSA:3.40.50.980 4 220 7.7E-32 T 29-03-2018 CVS48_RS15860 29ed04666de3c19192c75b5850972bd7 573 Gene3D G3DSA:3.40.50.980 221 372 1.8E-22 T 29-03-2018 CVS48_RS22095 bf9f1fecde4f3042408b747b779020db 194 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 14 185 3.3E-45 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CVS48_RS22095 bf9f1fecde4f3042408b747b779020db 194 SUPERFAMILY SSF110391 13 186 6.41E-45 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CVS48_RS22095 bf9f1fecde4f3042408b747b779020db 194 PIRSF PIRSF016897 3 191 2.7E-50 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CVS48_RS22095 bf9f1fecde4f3042408b747b779020db 194 Gene3D G3DSA:3.20.20.400 5 186 3.9E-46 T 29-03-2018 CVS48_RS16610 1476d343afee8fe250477e92fef77961 211 SMART SM01012 134 189 7.5E-12 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CVS48_RS16610 1476d343afee8fe250477e92fef77961 211 Pfam PF03861 ANTAR domain 137 189 2.8E-12 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CVS48_RS16610 1476d343afee8fe250477e92fef77961 211 Gene3D G3DSA:1.10.10.10 146 191 1.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16610 1476d343afee8fe250477e92fef77961 211 Gene3D G3DSA:3.40.50.2300 64 145 0.0014 T 29-03-2018 CVS48_RS16610 1476d343afee8fe250477e92fef77961 211 SUPERFAMILY SSF52172 7 189 4.97E-33 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS16610 1476d343afee8fe250477e92fef77961 211 PIRSF PIRSF036382 4 196 1.9E-31 T 29-03-2018 IPR008327 Signal transduction response regulator, antiterminator CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 298 327 1.6E-18 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 1.6E-18 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 1.6E-18 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 402 1.6E-18 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 Gene3D G3DSA:1.20.120.30 40 167 1.1E-8 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 Gene3D G3DSA:1.10.287.950 168 316 6.3E-9 T 29-03-2018 CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 Gene3D G3DSA:1.10.287.950 317 539 2.6E-49 T 29-03-2018 CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 SUPERFAMILY SSF58104 230 539 4.71E-62 T 29-03-2018 CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 SMART SM00283 270 538 3.9E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 SMART SM00304 210 262 1.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 176 2.1E-19 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CVS48_RS20695 a8a0e1ca09d0d188b846c4264c305fa8 539 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 343 504 1.4E-34 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 Gene3D G3DSA:3.50.50.60 197 376 1.3E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 SUPERFAMILY SSF55424 366 488 5.15E-36 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 7.5E-37 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 333 7.5E-37 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 196 214 7.5E-37 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 299 7.5E-37 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 7.5E-37 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 366 478 3.7E-31 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 488 4.2E-151 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 Gene3D G3DSA:3.50.50.60 1 185 5.2E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 SUPERFAMILY SSF51905 1 355 6.87E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 346 7.8E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 7.5E-63 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 196 221 7.5E-63 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 333 7.5E-63 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 453 473 7.5E-63 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 362 383 7.5E-63 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 446 7.5E-63 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 298 7.5E-63 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 7.5E-63 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 PIRSF PIRSF000350 1 487 1.8E-69 T 29-03-2018 CVS48_RS09270 aaaecc39a5d3b7d9952add0a3956d771 489 Gene3D G3DSA:3.30.390.30 377 489 9.2E-36 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS12440 d83b39f54d9d581b93914b6e43a11915 116 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 18 112 1.6E-34 T 29-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 CVS48_RS12440 d83b39f54d9d581b93914b6e43a11915 116 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 25 98 5.5E-14 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.537 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 SUPERFAMILY SSF56053 83 177 1.96E-34 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 Gene3D G3DSA:3.90.930.12 86 177 1.2E-37 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 PIRSF PIRSF002162 1 177 1.4E-47 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 Pfam PF00347 Ribosomal protein L6 12 82 1.0E-16 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 Pfam PF00347 Ribosomal protein L6 90 164 5.8E-18 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 SUPERFAMILY SSF56053 1 82 1.57E-24 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 2.5E-31 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 2.5E-31 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 2.5E-31 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 4.2E-72 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CVS48_RS06515 83d57b1889f5cad051b48f4e24ec377c 177 Gene3D G3DSA:3.90.930.12 5 85 2.0E-25 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS17480 7dadd28cc05612a735e896ed1c37eb81 225 Pfam PF02627 Carboxymuconolactone decarboxylase family 14 75 7.0E-6 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS17480 7dadd28cc05612a735e896ed1c37eb81 225 Pfam PF02627 Carboxymuconolactone decarboxylase family 134 206 5.3E-9 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS17480 7dadd28cc05612a735e896ed1c37eb81 225 SUPERFAMILY SSF69118 12 200 9.71E-38 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS17480 7dadd28cc05612a735e896ed1c37eb81 225 Gene3D G3DSA:1.20.1290.10 7 225 7.7E-36 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SUPERFAMILY SSF55781 215 375 3.73E-14 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 PRINTS PR00344 Bacterial sensor protein C-terminal signature 657 675 1.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 PRINTS PR00344 Bacterial sensor protein C-terminal signature 681 694 1.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 PRINTS PR00344 Bacterial sensor protein C-terminal signature 622 636 1.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 PRINTS PR00344 Bacterial sensor protein C-terminal signature 640 650 1.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 582 695 1.5E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Gene3D G3DSA:3.40.50.2300 1019 1151 1.1E-40 T 29-03-2018 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SMART SM00448 1026 1145 2.4E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SMART SM00448 880 994 3.4E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SMART SM00448 758 868 6.5E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SUPERFAMILY SSF52172 757 874 1.37E-25 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SUPERFAMILY SSF52172 880 1004 7.26E-25 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SUPERFAMILY SSF47384 452 536 2.94E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Gene3D G3DSA:3.40.50.2300 877 1018 3.2E-26 T 29-03-2018 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SMART SM00387 582 697 5.5E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Gene3D G3DSA:3.30.450.40 217 414 1.7E-21 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SMART SM00065 242 385 0.0083 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Gene3D G3DSA:3.30.565.10 539 705 5.3E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SUPERFAMILY SSF52172 1024 1150 1.24E-38 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Gene3D G3DSA:1.10.287.130 457 531 1.0E-16 T 29-03-2018 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Pfam PF00072 Response regulator receiver domain 1028 1145 8.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Pfam PF00072 Response regulator receiver domain 760 868 9.2E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Pfam PF00072 Response regulator receiver domain 882 992 3.2E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SMART SM00388 467 535 1.4E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Pfam PF00512 His Kinase A (phospho-acceptor) domain 468 535 2.4E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 SUPERFAMILY SSF55874 524 698 4.85E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Gene3D G3DSA:3.40.50.2300 754 876 3.7E-23 T 29-03-2018 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Pfam PF13185 GAF domain 241 375 3.3E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS18095 c9b39f80d79ac2728b80b8830d90849f 1151 Pfam PF05227 CHASE3 domain 51 179 4.2E-28 T 29-03-2018 IPR007891 CHASE3 CVS48_RS22935 d9e1d2fd7595880b707ce18378059ff2 126 PIRSF PIRSF016821 1 126 5.1E-44 T 29-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 CVS48_RS22935 d9e1d2fd7595880b707ce18378059ff2 126 Pfam PF01479 S4 domain 5 50 1.2E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS22935 d9e1d2fd7595880b707ce18378059ff2 126 SMART SM00363 4 69 5.2E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS22935 d9e1d2fd7595880b707ce18378059ff2 126 Gene3D G3DSA:3.10.290.10 1 100 6.1E-24 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS22935 d9e1d2fd7595880b707ce18378059ff2 126 SUPERFAMILY SSF55174 2 100 2.22E-28 T 29-03-2018 CVS48_RS16050 f184b506fe49293a54a9e1ba8ba50d45 197 SUPERFAMILY SSF55469 9 193 5.89E-37 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CVS48_RS16050 f184b506fe49293a54a9e1ba8ba50d45 197 Pfam PF00881 Nitroreductase family 14 172 3.1E-29 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CVS48_RS16050 f184b506fe49293a54a9e1ba8ba50d45 197 PIRSF PIRSF000232 5 196 1.9E-52 T 29-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like CVS48_RS16050 f184b506fe49293a54a9e1ba8ba50d45 197 Gene3D G3DSA:3.40.109.10 1 193 6.4E-31 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 SMART SM00382 320 511 1.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 SMART SM00382 34 239 3.8E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 SUPERFAMILY SSF52540 284 534 4.99E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 514 551 8.6E-9 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 281 1.9E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 Pfam PF00005 ABC transporter 312 462 1.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 Pfam PF00005 ABC transporter 26 189 2.9E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 Gene3D G3DSA:3.40.50.300 283 570 3.1E-76 T 29-03-2018 CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 Gene3D G3DSA:3.40.50.300 2 282 1.6E-64 T 29-03-2018 CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 ProSitePatterns PS00211 ABC transporters family signature. 435 449 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS25365 f1b29409ed58d1542e1ecc489027a4e4 586 SUPERFAMILY SSF52540 5 261 5.54E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13225 c4bc5fc55112905d4b932b11a27bed00 271 Gene3D G3DSA:2.60.40.1590 18 110 2.1E-32 T 29-03-2018 CVS48_RS13225 c4bc5fc55112905d4b932b11a27bed00 271 SUPERFAMILY SSF51261 119 266 1.23E-50 T 29-03-2018 IPR011055 Duplicated hybrid motif CVS48_RS13225 c4bc5fc55112905d4b932b11a27bed00 271 Gene3D G3DSA:2.70.70.10 111 271 4.6E-43 T 29-03-2018 CVS48_RS13225 c4bc5fc55112905d4b932b11a27bed00 271 Pfam PF01551 Peptidase family M23 168 262 1.1E-29 T 29-03-2018 IPR016047 Peptidase M23 CVS48_RS07510 c6303b59025039ea002537e7a87ba5e1 284 SUPERFAMILY SSF56281 8 282 1.23E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS07510 c6303b59025039ea002537e7a87ba5e1 284 SMART SM00849 14 202 6.3E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS07510 c6303b59025039ea002537e7a87ba5e1 284 Gene3D G3DSA:3.60.15.10 1 284 2.0E-52 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS07510 c6303b59025039ea002537e7a87ba5e1 284 Pfam PF00753 Metallo-beta-lactamase superfamily 14 202 2.3E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS13430 e34bc14f35dadae95d38a9122b9d4928 351 Gene3D G3DSA:3.90.870.10 6 226 5.2E-69 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CVS48_RS13430 e34bc14f35dadae95d38a9122b9d4928 351 Pfam PF03481 Putative GTP-binding controlling metal-binding 212 341 1.1E-19 T 29-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CVS48_RS13430 e34bc14f35dadae95d38a9122b9d4928 351 PIRSF PIRSF004930 4 346 4.5E-95 T 29-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CVS48_RS13430 e34bc14f35dadae95d38a9122b9d4928 351 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 221 1.5E-47 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CVS48_RS13430 e34bc14f35dadae95d38a9122b9d4928 351 SUPERFAMILY SSF55821 14 222 6.71E-52 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CVS48_RS13430 e34bc14f35dadae95d38a9122b9d4928 351 Pfam PF01300 Telomere recombination 21 210 2.3E-46 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 Pfam PF00384 Molybdopterin oxidoreductase 12 390 5.2E-20 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 SUPERFAMILY SSF50692 632 662 1.45E-43 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 SUPERFAMILY SSF50692 692 821 1.45E-43 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 Gene3D G3DSA:2.40.40.20 643 821 1.6E-37 T 29-03-2018 CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 Gene3D G3DSA:3.40.228.10 1 284 1.3E-71 T 29-03-2018 CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 SUPERFAMILY SSF53706 1 653 4.84E-232 T 29-03-2018 CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 Gene3D G3DSA:3.40.228.10 561 642 5.4E-10 T 29-03-2018 CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 Gene3D G3DSA:3.40.50.740 285 461 8.2E-25 T 29-03-2018 CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 Pfam PF01568 Molydopterin dinucleotide binding domain 698 814 1.8E-14 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CVS48_RS04325 790efe54f8f3d32ca79b6adbdbae49df 821 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 820 0.0 T 29-03-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 CVS48_RS20870 99b29581cc0dd38401c1d6f66b672613 238 SUPERFAMILY SSF47616 88 204 1.02E-29 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS20870 99b29581cc0dd38401c1d6f66b672613 238 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 79 4.5E-14 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS20870 99b29581cc0dd38401c1d6f66b672613 238 Pfam PF13410 Glutathione S-transferase, C-terminal domain 126 193 6.8E-12 T 29-03-2018 CVS48_RS20870 99b29581cc0dd38401c1d6f66b672613 238 SUPERFAMILY SSF52833 1 86 3.7E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS20870 99b29581cc0dd38401c1d6f66b672613 238 Gene3D G3DSA:3.40.30.10 1 98 2.4E-25 T 29-03-2018 CVS48_RS20870 99b29581cc0dd38401c1d6f66b672613 238 Gene3D G3DSA:1.20.1050.10 99 214 2.8E-28 T 29-03-2018 CVS48_RS02305 63de868abb90f00f733e92d24fb4cfc9 1001 SUPERFAMILY SSF103515 667 1000 4.84E-58 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS02305 63de868abb90f00f733e92d24fb4cfc9 1001 SMART SM00869 724 991 5.1E-45 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS02305 63de868abb90f00f733e92d24fb4cfc9 1001 Gene3D G3DSA:2.40.128.130 658 1001 1.8E-53 T 29-03-2018 CVS48_RS02305 63de868abb90f00f733e92d24fb4cfc9 1001 SUPERFAMILY SSF51126 408 578 4.39E-12 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS02305 63de868abb90f00f733e92d24fb4cfc9 1001 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 507 1000 4.4E-49 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 CVS48_RS02305 63de868abb90f00f733e92d24fb4cfc9 1001 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 130 164 5.6E-9 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS02305 63de868abb90f00f733e92d24fb4cfc9 1001 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 221 267 8.7E-11 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS02305 63de868abb90f00f733e92d24fb4cfc9 1001 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 325 370 8.6E-7 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS02305 63de868abb90f00f733e92d24fb4cfc9 1001 Pfam PF03797 Autotransporter beta-domain 727 981 1.9E-59 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS15570 62d9ce6293278d9fdfbf39466a13e9e0 566 Gene3D G3DSA:2.30.38.10 361 437 2.8E-19 T 29-03-2018 CVS48_RS15570 62d9ce6293278d9fdfbf39466a13e9e0 566 Gene3D G3DSA:3.40.50.980 192 348 4.2E-33 T 29-03-2018 CVS48_RS15570 62d9ce6293278d9fdfbf39466a13e9e0 566 Pfam PF00501 AMP-binding enzyme 27 443 1.4E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS15570 62d9ce6293278d9fdfbf39466a13e9e0 566 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 526 2.5E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS15570 62d9ce6293278d9fdfbf39466a13e9e0 566 Gene3D G3DSA:3.40.50.980 19 191 1.8E-38 T 29-03-2018 CVS48_RS15570 62d9ce6293278d9fdfbf39466a13e9e0 566 Gene3D G3DSA:3.30.300.30 438 542 8.7E-27 T 29-03-2018 CVS48_RS15570 62d9ce6293278d9fdfbf39466a13e9e0 566 SUPERFAMILY SSF56801 14 535 4.84E-138 T 29-03-2018 CVS48_RS15570 62d9ce6293278d9fdfbf39466a13e9e0 566 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS27150 7cb28c39c69af3705eacdbaaee11185e 250 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 219 5.5E-77 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS27150 7cb28c39c69af3705eacdbaaee11185e 250 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 222 5.7E-15 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CVS48_RS27150 7cb28c39c69af3705eacdbaaee11185e 250 Gene3D G3DSA:3.30.2350.10 8 230 4.7E-80 T 29-03-2018 CVS48_RS27150 7cb28c39c69af3705eacdbaaee11185e 250 SUPERFAMILY SSF55120 9 227 2.64E-79 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS27150 7cb28c39c69af3705eacdbaaee11185e 250 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 9 250 18.364 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS27150 7cb28c39c69af3705eacdbaaee11185e 250 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 180 8.4E-57 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CVS48_RS23220 b9ae7f05a61ebabde1a8f23a26650d53 274 Gene3D G3DSA:3.30.1130.10 137 274 6.0E-49 T 29-03-2018 CVS48_RS23220 b9ae7f05a61ebabde1a8f23a26650d53 274 PIRSF PIRSF004750 1 274 2.2E-123 T 29-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CVS48_RS23220 b9ae7f05a61ebabde1a8f23a26650d53 274 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 14 122 7.6E-47 T 29-03-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CVS48_RS23220 b9ae7f05a61ebabde1a8f23a26650d53 274 SUPERFAMILY SSF55620 177 257 1.04E-10 T 29-03-2018 CVS48_RS23220 b9ae7f05a61ebabde1a8f23a26650d53 274 Pfam PF14489 QueF-like protein 187 262 1.1E-27 T 29-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CVS48_RS23220 b9ae7f05a61ebabde1a8f23a26650d53 274 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 274 150.494 T 29-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CVS48_RS23220 b9ae7f05a61ebabde1a8f23a26650d53 274 Gene3D G3DSA:3.30.1130.10 14 129 2.6E-38 T 29-03-2018 CVS48_RS23220 b9ae7f05a61ebabde1a8f23a26650d53 274 TIGRFAM TIGR03138 QueF: queuine synthase 2 274 1.4E-126 T 29-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 SUPERFAMILY SSF63380 6 99 5.28E-25 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 Pfam PF00970 Oxidoreductase FAD-binding domain 16 97 1.5E-8 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 Gene3D G3DSA:2.40.30.10 2 96 3.3E-16 T 29-03-2018 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 SUPERFAMILY SSF52343 102 256 4.19E-40 T 29-03-2018 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 Pfam PF00175 Oxidoreductase NAD-binding domain 113 228 2.6E-7 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 1.0E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 1.0E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 1.0E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 1.0E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS19435 71cc3cccf34caf25888c4cd24d03251c 258 Gene3D G3DSA:3.40.50.80 97 258 3.6E-20 T 29-03-2018 CVS48_RS21920 6110807b305899ef0c18edaac8399af8 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 5.6E-36 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CVS48_RS21920 6110807b305899ef0c18edaac8399af8 107 SUPERFAMILY SSF89360 1 96 1.96E-31 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CVS48_RS21920 6110807b305899ef0c18edaac8399af8 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 1.9E-23 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CVS48_RS21920 6110807b305899ef0c18edaac8399af8 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 7.9E-52 T 29-03-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 CVS48_RS21920 6110807b305899ef0c18edaac8399af8 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CVS48_RS21920 6110807b305899ef0c18edaac8399af8 107 Gene3D G3DSA:2.60.300.12 2 107 1.7E-37 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CVS48_RS08890 6025fd32eccc2a60e9ff3d92c6dd4abf 95 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 90 1.1E-16 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CVS48_RS08890 6025fd32eccc2a60e9ff3d92c6dd4abf 95 Gene3D G3DSA:3.30.2310.20 3 90 2.2E-4 T 29-03-2018 CVS48_RS08890 6025fd32eccc2a60e9ff3d92c6dd4abf 95 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 90 6.0E-9 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 Pfam PF02203 Tar ligand binding domain homologue 1 151 1.2E-17 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 Gene3D G3DSA:1.10.287.950 322 517 3.8E-51 T 29-03-2018 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 Gene3D G3DSA:1.10.287.950 180 321 7.0E-22 T 29-03-2018 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 SMART SM00304 213 265 2.0E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 Gene3D G3DSA:1.20.120.30 23 179 4.7E-18 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 SUPERFAMILY SSF58104 233 519 3.66E-78 T 29-03-2018 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 1.4E-55 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 SUPERFAMILY SSF47170 25 177 1.11E-16 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 9.1E-66 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 9.1E-66 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 9.1E-66 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 9.1E-66 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 9.1E-66 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 Pfam PF00672 HAMP domain 213 261 7.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS16915 3678044d8d7dd8ec0fc678dc8455ff8b 647 SMART SM00283 266 513 3.6E-98 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS18590 fa6b77b0e879c7b34c7503afa216d245 278 Pfam PF00582 Universal stress protein family 154 275 5.4E-8 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS18590 fa6b77b0e879c7b34c7503afa216d245 278 Gene3D G3DSA:3.40.50.620 1 145 2.5E-9 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS18590 fa6b77b0e879c7b34c7503afa216d245 278 SUPERFAMILY SSF52402 1 143 3.43E-12 T 29-03-2018 CVS48_RS18590 fa6b77b0e879c7b34c7503afa216d245 278 SUPERFAMILY SSF52402 154 276 3.6E-17 T 29-03-2018 CVS48_RS18590 fa6b77b0e879c7b34c7503afa216d245 278 Gene3D G3DSA:3.40.50.620 146 278 2.9E-17 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS09525 1af0166d802b5c6f3f00568192d6fe64 271 Gene3D G3DSA:3.40.50.80 136 270 4.5E-41 T 29-03-2018 CVS48_RS09525 1af0166d802b5c6f3f00568192d6fe64 271 Gene3D G3DSA:2.40.30.10 10 135 5.8E-31 T 29-03-2018 CVS48_RS09525 1af0166d802b5c6f3f00568192d6fe64 271 Pfam PF08021 Siderophore-interacting FAD-binding domain 21 135 6.3E-34 T 29-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CVS48_RS09525 1af0166d802b5c6f3f00568192d6fe64 271 Pfam PF04954 Siderophore-interacting protein 143 261 7.0E-39 T 29-03-2018 IPR007037 Siderophore-interacting protein CVS48_RS09525 1af0166d802b5c6f3f00568192d6fe64 271 SUPERFAMILY SSF63380 10 138 1.48E-12 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 Pfam PF03466 LysR substrate binding domain 90 291 5.0E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 Gene3D G3DSA:3.40.190.10 174 260 5.7E-23 T 29-03-2018 CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 SUPERFAMILY SSF46785 1 112 2.21E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 SUPERFAMILY SSF53850 90 291 1.63E-42 T 29-03-2018 CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 Gene3D G3DSA:1.10.10.10 1 84 4.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 8.4E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20365 60a73162ab2102966408d2b66b9c7dfd 292 Gene3D G3DSA:3.40.190.10 89 173 5.3E-15 T 29-03-2018 CVS48_RS14260 86b0fb920d75856f4172346babf013eb 803 SUPERFAMILY SSF82861 534 616 8.89E-10 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CVS48_RS14260 86b0fb920d75856f4172346babf013eb 803 Pfam PF00924 Mechanosensitive ion channel 576 773 1.1E-40 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CVS48_RS14260 86b0fb920d75856f4172346babf013eb 803 SUPERFAMILY SSF50182 618 683 3.04E-15 T 29-03-2018 IPR010920 LSM domain CVS48_RS14260 86b0fb920d75856f4172346babf013eb 803 Gene3D G3DSA:2.30.30.60 634 684 7.2E-13 T 29-03-2018 CVS48_RS14260 86b0fb920d75856f4172346babf013eb 803 Pfam PF12607 Protein of unknown function (DUF3772) 140 202 7.1E-18 T 29-03-2018 IPR022249 Domain of unknown function DUF3772 CVS48_RS14260 86b0fb920d75856f4172346babf013eb 803 Gene3D G3DSA:3.30.70.100 689 779 6.0E-12 T 29-03-2018 CVS48_RS14260 86b0fb920d75856f4172346babf013eb 803 SUPERFAMILY SSF82689 685 779 3.79E-13 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CVS48_RS26290 380acb97fd6ab2da9f0e8a2c28b52073 327 SUPERFAMILY SSF52540 33 255 1.03E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26290 380acb97fd6ab2da9f0e8a2c28b52073 327 SMART SM00382 49 233 1.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS26290 380acb97fd6ab2da9f0e8a2c28b52073 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 317 7.6E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS26290 380acb97fd6ab2da9f0e8a2c28b52073 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 9.4E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS26290 380acb97fd6ab2da9f0e8a2c28b52073 327 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS26290 380acb97fd6ab2da9f0e8a2c28b52073 327 Pfam PF00005 ABC transporter 41 184 4.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS26290 380acb97fd6ab2da9f0e8a2c28b52073 327 Gene3D G3DSA:3.40.50.300 6 325 5.0E-72 T 29-03-2018 CVS48_RS13315 5e2aa776930c0c55a88dc60ee707d55c 387 PIRSF PIRSF007313 1 363 9.5E-153 T 29-03-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 CVS48_RS13315 5e2aa776930c0c55a88dc60ee707d55c 387 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 1 352 1.5E-159 T 29-03-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 CVS48_RS05065 6a4923b23d59732fe76ddbd1a2c31484 266 PRINTS PR01805 VacJ lipoprotein signature 32 45 1.3E-26 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CVS48_RS05065 6a4923b23d59732fe76ddbd1a2c31484 266 PRINTS PR01805 VacJ lipoprotein signature 136 153 1.3E-26 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CVS48_RS05065 6a4923b23d59732fe76ddbd1a2c31484 266 PRINTS PR01805 VacJ lipoprotein signature 100 117 1.3E-26 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CVS48_RS05065 6a4923b23d59732fe76ddbd1a2c31484 266 PRINTS PR01805 VacJ lipoprotein signature 49 65 1.3E-26 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CVS48_RS05065 6a4923b23d59732fe76ddbd1a2c31484 266 Pfam PF04333 MlaA lipoprotein 31 228 1.2E-72 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CVS48_RS29080 722aa4e11f0ef456ba81d2634eea571d 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 1.4E-152 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CVS48_RS06810 fa49537d8f961c92820abbbd139e387c 933 SMART SM00912 43 156 8.3E-38 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06810 fa49537d8f961c92820abbbd139e387c 933 SUPERFAMILY SSF51126 46 337 5.65E-44 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS06810 fa49537d8f961c92820abbbd139e387c 933 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 78 152 7.8E-26 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06810 fa49537d8f961c92820abbbd139e387c 933 Pfam PF05860 haemagglutination activity domain 43 156 3.9E-25 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06810 fa49537d8f961c92820abbbd139e387c 933 Gene3D G3DSA:2.160.20.10 315 483 0.013 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS06810 fa49537d8f961c92820abbbd139e387c 933 Pfam PF07581 The GLUG motif 679 703 6.7E-5 T 29-03-2018 IPR011493 GLUG CVS48_RS06810 fa49537d8f961c92820abbbd139e387c 933 Gene3D G3DSA:2.160.20.10 38 314 1.1E-55 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS22345 61190a9d4d03d37addbab30ab9a9f5fb 213 Gene3D G3DSA:1.10.357.10 80 208 1.4E-27 T 29-03-2018 CVS48_RS22345 61190a9d4d03d37addbab30ab9a9f5fb 213 Gene3D G3DSA:1.10.10.60 24 79 1.7E-15 T 29-03-2018 CVS48_RS22345 61190a9d4d03d37addbab30ab9a9f5fb 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 1.6E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS22345 61190a9d4d03d37addbab30ab9a9f5fb 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 1.6E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS22345 61190a9d4d03d37addbab30ab9a9f5fb 213 SUPERFAMILY SSF46689 29 95 1.23E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS22345 61190a9d4d03d37addbab30ab9a9f5fb 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 1.7E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS22345 61190a9d4d03d37addbab30ab9a9f5fb 213 SUPERFAMILY SSF48498 102 206 1.38E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 PIRSF PIRSF000429 1 401 1.2E-117 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 Gene3D G3DSA:3.40.47.10 1 277 1.7E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 Pfam PF02803 Thiolase, C-terminal domain 278 398 1.2E-41 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 1.1E-129 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 SUPERFAMILY SSF53901 279 399 1.98E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 Pfam PF00108 Thiolase, N-terminal domain 5 269 1.6E-64 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 SUPERFAMILY SSF53901 1 274 4.32E-69 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 Gene3D G3DSA:3.40.47.10 278 397 3.9E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CVS48_RS08650 c6dfd0858e26eceedaa90ddb553e3ad5 401 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CVS48_RS10245 e13aa9b67321b580d8fb316c9450af03 374 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 162 2.2E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS10245 e13aa9b67321b580d8fb316c9450af03 374 SMART SM00829 18 368 1.2E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS10245 e13aa9b67321b580d8fb316c9450af03 374 SUPERFAMILY SSF50129 1 199 4.57E-58 T 29-03-2018 IPR011032 GroES-like CVS48_RS10245 e13aa9b67321b580d8fb316c9450af03 374 Gene3D G3DSA:3.40.50.720 204 321 4.1E-25 T 29-03-2018 CVS48_RS10245 e13aa9b67321b580d8fb316c9450af03 374 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS10245 e13aa9b67321b580d8fb316c9450af03 374 Gene3D G3DSA:3.90.180.10 1 203 2.0E-55 T 29-03-2018 CVS48_RS10245 e13aa9b67321b580d8fb316c9450af03 374 Pfam PF00107 Zinc-binding dehydrogenase 204 321 9.1E-27 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS10245 e13aa9b67321b580d8fb316c9450af03 374 SUPERFAMILY SSF51735 166 338 3.11E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07270 a13d7ca2aa7d04ca42001e41bed3582d 288 SUPERFAMILY SSF81345 12 270 5.49E-24 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CVS48_RS07270 a13d7ca2aa7d04ca42001e41bed3582d 288 Gene3D G3DSA:1.10.3470.10 10 278 2.2E-19 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS07270 a13d7ca2aa7d04ca42001e41bed3582d 288 Pfam PF00950 ABC 3 transport family 14 271 1.0E-51 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 Gene3D G3DSA:3.40.120.10 4 152 1.6E-30 T 29-03-2018 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 101 110 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 Gene3D G3DSA:3.40.120.10 264 365 5.8E-22 T 29-03-2018 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 Gene3D G3DSA:3.40.120.10 156 263 1.7E-35 T 29-03-2018 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 SUPERFAMILY SSF55957 369 464 7.85E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 SUPERFAMILY SSF53738 260 356 1.77E-30 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 Gene3D G3DSA:3.30.310.50 366 463 8.9E-14 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 121 1.3E-30 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 SUPERFAMILY SSF53738 8 133 8.63E-35 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 256 1.9E-27 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 357 1.3E-19 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 452 5.0E-11 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 SUPERFAMILY SSF53738 157 258 6.67E-33 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 207 220 1.3E-23 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 1.3E-23 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 1.3E-23 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS10725 fb905f817dd3d7b3fd539d02cc59ab63 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 100 114 1.3E-23 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS27060 b8d8c25b2109424218d1d5f6f377c2ae 276 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 12 263 7.9E-111 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 CVS48_RS27060 b8d8c25b2109424218d1d5f6f377c2ae 276 Gene3D G3DSA:3.40.50.1000 99 266 4.4E-27 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS27060 b8d8c25b2109424218d1d5f6f377c2ae 276 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 78 210 2.3E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS27060 b8d8c25b2109424218d1d5f6f377c2ae 276 SUPERFAMILY SSF56784 13 265 9.17E-60 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS27060 b8d8c25b2109424218d1d5f6f377c2ae 276 Gene3D G3DSA:1.10.150.240 31 98 4.9E-33 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CVS48_RS27060 b8d8c25b2109424218d1d5f6f377c2ae 276 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 210 4.2E-11 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS27060 b8d8c25b2109424218d1d5f6f377c2ae 276 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 276 128.664 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 Pfam PF09382 RQC domain 400 516 8.7E-38 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 Pfam PF00570 HRDC domain 539 602 4.6E-22 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 SMART SM00487 15 211 3.7E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 SMART SM00956 405 512 1.4E-48 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 SMART SM00341 534 607 1.9E-9 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 461 3.4E-150 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 Gene3D G3DSA:3.40.50.300 3 201 4.8E-31 T 29-03-2018 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 Gene3D G3DSA:1.10.10.10 398 518 5.0E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 9 604 1.1E-239 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 Gene3D G3DSA:3.40.50.300 203 397 3.9E-42 T 29-03-2018 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 Pfam PF16124 RecQ zinc-binding 337 398 3.6E-17 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 SUPERFAMILY SSF52540 5 189 2.34E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 SUPERFAMILY SSF47819 535 606 2.4E-21 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 Pfam PF00270 DEAD/DEAH box helicase 22 180 4.2E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 SUPERFAMILY SSF52540 201 452 3.29E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 Gene3D G3DSA:1.10.150.80 519 607 4.1E-23 T 29-03-2018 CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 SMART SM00490 244 325 1.1E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS01460 559d18c63243062784d5d01d2901be74 609 Pfam PF00271 Helicase conserved C-terminal domain 218 324 1.5E-14 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS26115 113cfe2b21f0720f4003d2890959f325 602 Gene3D G3DSA:1.20.91.10 234 317 1.9E-11 T 29-03-2018 CVS48_RS26115 113cfe2b21f0720f4003d2890959f325 602 Pfam PF00999 Sodium/hydrogen exchanger family 14 377 4.3E-69 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CVS48_RS26115 113cfe2b21f0720f4003d2890959f325 602 Gene3D G3DSA:3.40.50.720 406 564 4.7E-16 T 29-03-2018 CVS48_RS26115 113cfe2b21f0720f4003d2890959f325 602 SUPERFAMILY SSF51735 407 534 4.22E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS26115 113cfe2b21f0720f4003d2890959f325 602 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 18 289 6.9E-81 T 29-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 CVS48_RS26115 113cfe2b21f0720f4003d2890959f325 602 Pfam PF02254 TrkA-N domain 407 519 1.1E-19 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 Gene3D G3DSA:3.30.1490.20 85 187 3.7E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 Gene3D G3DSA:3.40.50.20 2 84 7.1E-37 T 29-03-2018 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 SUPERFAMILY SSF51246 331 424 2.43E-29 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 SUPERFAMILY SSF56059 102 321 3.18E-60 T 29-03-2018 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 298 9.2E-75 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 9.9E-36 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 424 6.0E-166 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 422 5.0E-28 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 424 41.587 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 SMART SM01209 101 298 5.3E-133 T 29-03-2018 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 Gene3D G3DSA:3.90.600.10 332 425 1.8E-32 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 SUPERFAMILY SSF52440 1 101 1.24E-34 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 SMART SM01210 332 424 1.0E-50 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS14345 2949dc02242cb02eb7fd085f2e5eb460 435 Gene3D G3DSA:3.30.470.20 189 331 4.5E-57 T 29-03-2018 CVS48_RS22520 64daa7375c2e788d84174bd1333d2fcd 255 Gene3D G3DSA:3.20.20.60 2 253 1.5E-36 T 29-03-2018 CVS48_RS22520 64daa7375c2e788d84174bd1333d2fcd 255 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 243 3.9E-52 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CVS48_RS22520 64daa7375c2e788d84174bd1333d2fcd 255 SUPERFAMILY SSF51621 5 251 1.16E-76 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS22520 64daa7375c2e788d84174bd1333d2fcd 255 TIGRFAM TIGR03239 GarL: 2-dehydro-3-deoxyglucarate aldolase 7 254 8.2E-136 T 29-03-2018 IPR017648 5-keto-4-deoxy-D-glucarate aldolase GO:0008672|GO:0019394 KEGG: 00053+4.1.2.20 CVS48_RS01430 b9f21d85fa7a4381284b7968f300b550 308 Gene3D G3DSA:3.40.50.720 1 305 2.3E-43 T 29-03-2018 CVS48_RS01430 b9f21d85fa7a4381284b7968f300b550 308 SUPERFAMILY SSF51735 1 260 2.64E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS01430 b9f21d85fa7a4381284b7968f300b550 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 217 1.6E-22 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS19565 2c379088da77254875f8f9333ad5df52 318 SUPERFAMILY SSF46626 170 270 3.49E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS19565 2c379088da77254875f8f9333ad5df52 318 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 179 259 1.8E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS19565 2c379088da77254875f8f9333ad5df52 318 SUPERFAMILY SSF46626 53 159 4.39E-27 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS19565 2c379088da77254875f8f9333ad5df52 318 Gene3D G3DSA:1.10.760.10 163 262 1.7E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS19565 2c379088da77254875f8f9333ad5df52 318 Gene3D G3DSA:1.10.760.10 57 155 3.3E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS03905 d828faa5c1bb18bae0e9d5af1b8233f5 234 Pfam PF00005 ABC transporter 19 162 1.7E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS03905 d828faa5c1bb18bae0e9d5af1b8233f5 234 SUPERFAMILY SSF52540 2 231 2.01E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03905 d828faa5c1bb18bae0e9d5af1b8233f5 234 Gene3D G3DSA:3.40.50.300 1 232 3.8E-50 T 29-03-2018 CVS48_RS03905 d828faa5c1bb18bae0e9d5af1b8233f5 234 SMART SM00382 26 211 1.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03905 d828faa5c1bb18bae0e9d5af1b8233f5 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS09760 c3108256b3c044d42220c44aaa462533 331 SUPERFAMILY SSF51735 123 290 9.52E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09760 c3108256b3c044d42220c44aaa462533 331 SMART SM00829 17 328 1.3E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS09760 c3108256b3c044d42220c44aaa462533 331 SUPERFAMILY SSF50129 19 150 1.67E-37 T 29-03-2018 IPR011032 GroES-like CVS48_RS09760 c3108256b3c044d42220c44aaa462533 331 Gene3D G3DSA:3.40.50.720 156 273 6.5E-16 T 29-03-2018 CVS48_RS09760 c3108256b3c044d42220c44aaa462533 331 Pfam PF00107 Zinc-binding dehydrogenase 165 285 4.9E-11 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS09760 c3108256b3c044d42220c44aaa462533 331 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 22 329 3.8E-119 T 29-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CVS48_RS09760 c3108256b3c044d42220c44aaa462533 331 Gene3D G3DSA:3.90.180.10 8 155 3.0E-30 T 29-03-2018 CVS48_RS10620 e8b0f55753e2cd11a10149b8692703e5 313 SUPERFAMILY SSF161098 91 297 4.19E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10620 e8b0f55753e2cd11a10149b8692703e5 313 Gene3D G3DSA:1.10.3720.10 3 301 2.0E-38 T 29-03-2018 CVS48_RS10620 e8b0f55753e2cd11a10149b8692703e5 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 9.8E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS23890 4a686bdc015aa9d96106e78444685be9 320 PIRSF PIRSF017082 1 319 2.7E-58 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23890 4a686bdc015aa9d96106e78444685be9 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 315 4.6E-49 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23890 4a686bdc015aa9d96106e78444685be9 320 Gene3D G3DSA:3.40.190.10 119 283 4.0E-5 T 29-03-2018 CVS48_RS23890 4a686bdc015aa9d96106e78444685be9 320 SUPERFAMILY SSF53850 43 283 1.19E-7 T 29-03-2018 CVS48_RS01870 ed502829c2637168a919d625608e153e 272 Gene3D G3DSA:3.90.226.10 14 229 1.4E-63 T 29-03-2018 CVS48_RS01870 ed502829c2637168a919d625608e153e 272 SUPERFAMILY SSF52096 11 271 3.85E-80 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS01870 ed502829c2637168a919d625608e153e 272 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 17 271 1.2E-106 T 29-03-2018 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 CVS48_RS01870 ed502829c2637168a919d625608e153e 272 Gene3D G3DSA:1.10.12.10 230 272 2.4E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS01870 ed502829c2637168a919d625608e153e 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 271 2.4E-64 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS05785 a0efdd74c50e9b75af10e30e7c819f3e 169 SUPERFAMILY SSF52309 1 163 6.1E-46 T 29-03-2018 CVS48_RS05785 a0efdd74c50e9b75af10e30e7c819f3e 169 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 144 1.5E-45 T 29-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 CVS48_RS05785 a0efdd74c50e9b75af10e30e7c819f3e 169 Gene3D G3DSA:3.40.50.450 1 169 2.1E-38 T 29-03-2018 CVS48_RS11985 f25bcf5cfc29e42da44479902c671ec5 258 Gene3D G3DSA:1.20.1110.10 6 233 0.0011 T 29-03-2018 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 SUPERFAMILY SSF53901 278 397 3.2E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 Gene3D G3DSA:3.40.47.10 1 280 5.6E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 Pfam PF02803 Thiolase, C-terminal domain 277 397 6.1E-45 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 397 7.7E-134 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 Gene3D G3DSA:3.40.47.10 281 396 1.5E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 SUPERFAMILY SSF53901 7 276 4.14E-69 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 90 108 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 PIRSF PIRSF000429 2 399 8.2E-124 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS23865 d1c95ad8e88777427c45b9d892a0fdb2 399 Pfam PF00108 Thiolase, N-terminal domain 9 267 5.1E-67 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS05830 4d6f9440d6cb09bf5f1408ccff077229 426 Gene3D G3DSA:2.30.40.10 1 65 5.5E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS05830 4d6f9440d6cb09bf5f1408ccff077229 426 Pfam PF03841 L-seryl-tRNA selenium transferase 306 395 1.2E-4 T 29-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CVS48_RS05830 4d6f9440d6cb09bf5f1408ccff077229 426 SUPERFAMILY SSF51338 1 64 3.18E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS05830 4d6f9440d6cb09bf5f1408ccff077229 426 SUPERFAMILY SSF51556 52 371 7.61E-109 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS05830 4d6f9440d6cb09bf5f1408ccff077229 426 Gene3D G3DSA:3.20.20.140 66 360 5.0E-48 T 29-03-2018 CVS48_RS05830 4d6f9440d6cb09bf5f1408ccff077229 426 Pfam PF07969 Amidohydrolase family 40 400 9.8E-51 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS02825 dab710266d33f504c8f584546e2e6bd6 240 SMART SM00479 2 174 1.3E-44 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CVS48_RS02825 dab710266d33f504c8f584546e2e6bd6 240 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 213 1.5E-58 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS02825 dab710266d33f504c8f584546e2e6bd6 240 Pfam PF00929 Exonuclease 4 164 3.3E-33 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CVS48_RS02825 dab710266d33f504c8f584546e2e6bd6 240 Gene3D G3DSA:3.30.420.10 2 176 1.9E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS02825 dab710266d33f504c8f584546e2e6bd6 240 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 232 1.0E-87 T 29-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS02825 dab710266d33f504c8f584546e2e6bd6 240 SUPERFAMILY SSF53098 1 174 7.59E-53 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 Pfam PF01225 Mur ligase family, catalytic domain 2 97 3.8E-16 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 Gene3D G3DSA:3.40.50.720 1 90 2.9E-10 T 29-03-2018 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 Gene3D G3DSA:3.90.190.20 313 454 1.1E-28 T 29-03-2018 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 SUPERFAMILY SSF51984 1 89 9.42E-19 T 29-03-2018 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 Gene3D G3DSA:3.40.1190.10 91 312 2.5E-40 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 SUPERFAMILY SSF53244 310 452 5.49E-37 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 453 57.576 T 29-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 Pfam PF08245 Mur ligase middle domain 108 291 3.4E-20 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 SUPERFAMILY SSF53623 98 308 7.85E-47 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 453 3.2E-201 T 29-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 CVS48_RS03200 267c8fbdd80fda9b43410514d432ba3b 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 387 2.4E-10 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS07570 b7b79cb3eeac4edb7519ea34d4223472 153 Gene3D G3DSA:1.10.10.10 24 152 1.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07570 b7b79cb3eeac4edb7519ea34d4223472 153 SUPERFAMILY SSF46785 11 146 2.01E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07570 b7b79cb3eeac4edb7519ea34d4223472 153 Pfam PF01047 MarR family 44 102 1.5E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS07570 b7b79cb3eeac4edb7519ea34d4223472 153 SMART SM00347 37 136 1.1E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS07570 b7b79cb3eeac4edb7519ea34d4223472 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 1.3E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS07570 b7b79cb3eeac4edb7519ea34d4223472 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 1.3E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS07570 b7b79cb3eeac4edb7519ea34d4223472 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 1.3E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS28875 82b40729a3d8017fded9a5f998b2f52c 130 Gene3D G3DSA:1.10.1220.10 94 128 6.3E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CVS48_RS28875 82b40729a3d8017fded9a5f998b2f52c 130 Gene3D G3DSA:3.30.2390.10 1 71 1.4E-21 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like CVS48_RS28875 82b40729a3d8017fded9a5f998b2f52c 130 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 127 3.0E-50 T 29-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system CVS48_RS28875 82b40729a3d8017fded9a5f998b2f52c 130 SUPERFAMILY SSF143100 2 65 9.55E-17 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like CVS48_RS05550 9f770df1443e35145611e3ebf1bee331 506 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 439 3.1E-144 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 SUPERFAMILY SSF52540 12 276 7.19E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 Gene3D G3DSA:3.40.50.300 34 277 5.8E-47 T 29-03-2018 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 Gene3D G3DSA:3.30.250.10 278 334 1.9E-25 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 SUPERFAMILY SSF54752 277 335 1.7E-21 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 Hamap MF_00268 Protein RecA [recA]. 13 338 51.669 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 SMART SM00382 66 237 4.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 PRINTS PR00142 RecA protein signature 219 247 1.7E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 PRINTS PR00142 RecA protein signature 252 281 1.7E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 PRINTS PR00142 RecA protein signature 306 323 1.7E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 PRINTS PR00142 RecA protein signature 102 131 1.7E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 PRINTS PR00142 RecA protein signature 136 165 1.7E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 PRINTS PR00142 RecA protein signature 174 203 1.7E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 12 333 3.1E-172 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 Pfam PF00154 recA bacterial DNA recombination protein 15 277 2.9E-145 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CVS48_RS26845 97e8da08cdb7eaa65eeaed434cc0d915 353 ProSitePatterns PS00321 recA signature. 222 230 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CVS48_RS19845 ea952cb700063285f64b0d7699961a26 340 SUPERFAMILY SSF51679 7 327 1.96E-80 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CVS48_RS19845 ea952cb700063285f64b0d7699961a26 340 Gene3D G3DSA:3.20.20.30 12 330 8.2E-74 T 29-03-2018 CVS48_RS19845 ea952cb700063285f64b0d7699961a26 340 Pfam PF00296 Luciferase-like monooxygenase 20 303 9.1E-38 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CVS48_RS19845 ea952cb700063285f64b0d7699961a26 340 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 9 327 5.4E-130 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CVS48_RS20440 d7a432b301bce473fbe4f5c9361dd146 136 SUPERFAMILY SSF54909 1 119 8.04E-35 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS20440 d7a432b301bce473fbe4f5c9361dd146 136 Gene3D G3DSA:3.30.70.1060 1 119 2.5E-38 T 29-03-2018 CVS48_RS20440 d7a432b301bce473fbe4f5c9361dd146 136 Pfam PF03795 YCII-related domain 1 111 3.4E-22 T 29-03-2018 IPR005545 YCII-related CVS48_RS23110 3688dfadad0fae3812043d6b4e936f8d 390 SUPERFAMILY SSF51604 127 386 1.17E-67 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS23110 3688dfadad0fae3812043d6b4e936f8d 390 SUPERFAMILY SSF54826 1 143 2.55E-34 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS23110 3688dfadad0fae3812043d6b4e936f8d 390 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 41 139 1.0E-21 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CVS48_RS23110 3688dfadad0fae3812043d6b4e936f8d 390 SMART SM00922 158 261 1.0E-22 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CVS48_RS23110 3688dfadad0fae3812043d6b4e936f8d 390 Gene3D G3DSA:3.30.390.10 1 137 9.1E-48 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS23110 3688dfadad0fae3812043d6b4e936f8d 390 Pfam PF13378 Enolase C-terminal domain-like 161 381 3.1E-53 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS23110 3688dfadad0fae3812043d6b4e936f8d 390 Gene3D G3DSA:3.20.20.120 138 379 6.6E-56 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS16710 2b6ec518c4bd59100880cfe36008cf39 270 SUPERFAMILY SSF51197 3 246 2.38E-37 T 29-03-2018 CVS48_RS16710 2b6ec518c4bd59100880cfe36008cf39 270 Gene3D G3DSA:2.60.120.620 1 240 2.2E-33 T 29-03-2018 CVS48_RS16710 2b6ec518c4bd59100880cfe36008cf39 270 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 9 219 1.2E-22 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CVS48_RS08505 5dbfbd240e3e767675865d074cb1a2d7 224 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 20 167 1.1E-19 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN CVS48_RS08505 5dbfbd240e3e767675865d074cb1a2d7 224 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 11 154 2.8E-10 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 Pfam PF00271 Helicase conserved C-terminal domain 269 363 9.8E-12 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 Gene3D G3DSA:3.40.50.300 256 400 1.1E-21 T 29-03-2018 CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 SUPERFAMILY SSF52540 41 209 1.94E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 SUPERFAMILY SSF52540 240 375 1.94E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 Gene3D G3DSA:3.40.50.300 20 218 5.0E-31 T 29-03-2018 CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 Pfam PF08494 DEAD/H associated 605 792 1.1E-42 T 29-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 20 821 0.0 T 29-03-2018 IPR026362 DEXH box helicase, DNA ligase-associated CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 PIRSF PIRSF037307 6 824 3.3E-134 T 29-03-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 Pfam PF00270 DEAD/DEAH box helicase 34 207 5.0E-25 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 SMART SM00490 286 368 2.2E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS18775 e518bc20b08ab9eefb36f74a458f96f5 828 SMART SM00487 27 237 2.4E-20 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS18980 e15139dbd5303be300ec6ad298ba0e68 366 Pfam PF05359 Domain of Unknown Function (DUF748) 142 280 3.2E-15 T 29-03-2018 IPR008023 Protein of unknown function DUF748 CVS48_RS12750 bb14bef3a60e4ffd7a020784aaaf27a1 95 Pfam PF03413 Peptidase propeptide and YPEB domain 32 84 3.6E-7 T 29-03-2018 IPR025711 PepSY domain CVS48_RS12750 bb14bef3a60e4ffd7a020784aaaf27a1 95 Gene3D G3DSA:3.10.450.40 13 85 5.9E-10 T 29-03-2018 CVS48_RS14495 4fbde2b49b6833ea3384177e83562837 334 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 13 332 2.4E-108 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CVS48_RS14495 4fbde2b49b6833ea3384177e83562837 334 SUPERFAMILY SSF53850 38 333 5.58E-89 T 29-03-2018 CVS48_RS14495 4fbde2b49b6833ea3384177e83562837 334 Gene3D G3DSA:3.40.190.10 35 175 4.6E-26 T 29-03-2018 CVS48_RS14495 4fbde2b49b6833ea3384177e83562837 334 Gene3D G3DSA:3.40.190.10 182 334 3.3E-41 T 29-03-2018 CVS48_RS14495 4fbde2b49b6833ea3384177e83562837 334 Pfam PF16868 NMT1-like family 43 332 8.8E-97 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CVS48_RS11455 eeb9dc65b166b81f0843664364e04db8 91 SUPERFAMILY SSF143011 1 87 2.86E-5 T 29-03-2018 IPR035095 Toxin RelE-like domain CVS48_RS11455 eeb9dc65b166b81f0843664364e04db8 91 Gene3D G3DSA:3.30.2310.20 1 90 4.6E-4 T 29-03-2018 CVS48_RS11455 eeb9dc65b166b81f0843664364e04db8 91 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 90 1.6E-14 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 Gene3D G3DSA:3.40.50.300 1 79 2.0E-8 T 29-03-2018 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 Gene3D G3DSA:3.10.20.30 263 362 2.6E-45 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 SUPERFAMILY SSF81271 279 359 4.36E-36 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 SUPERFAMILY SSF52540 3 301 4.91E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 5.8E-155 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 2.0E-39 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 PIRSF PIRSF006641 1 363 2.4E-150 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.8E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.8E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.8E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.8E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 43.59 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 Pfam PF01926 50S ribosome-binding GTPase 5 125 1.1E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS10890 ccabc2eefcfb8f70ba7a4a10e864c395 363 Gene3D G3DSA:1.10.150.300 110 200 3.8E-28 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CVS48_RS11185 d73990bfc23c5d677284950dc6398071 384 PIRSF PIRSF016578 9 383 6.5E-12 T 29-03-2018 CVS48_RS11185 d73990bfc23c5d677284950dc6398071 384 Gene3D G3DSA:1.10.540.10 1 120 6.0E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS11185 d73990bfc23c5d677284950dc6398071 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 9.0E-22 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS11185 d73990bfc23c5d677284950dc6398071 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 377 5.6E-44 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS11185 d73990bfc23c5d677284950dc6398071 384 SUPERFAMILY SSF47203 227 379 9.83E-55 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS11185 d73990bfc23c5d677284950dc6398071 384 SUPERFAMILY SSF56645 1 239 5.63E-62 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS11185 d73990bfc23c5d677284950dc6398071 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 3.6E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS11185 d73990bfc23c5d677284950dc6398071 384 Gene3D G3DSA:1.20.140.10 217 383 1.1E-56 T 29-03-2018 CVS48_RS11185 d73990bfc23c5d677284950dc6398071 384 Gene3D G3DSA:2.40.110.10 121 216 4.4E-30 T 29-03-2018 CVS48_RS06155 7e5174e89e34d2f16814454106f06e5d 241 Pfam PF02527 rRNA small subunit methyltransferase G 32 217 1.7E-45 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CVS48_RS06155 7e5174e89e34d2f16814454106f06e5d 241 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 36 222 7.2E-43 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CVS48_RS06155 7e5174e89e34d2f16814454106f06e5d 241 SUPERFAMILY SSF53335 17 225 3.93E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS06155 7e5174e89e34d2f16814454106f06e5d 241 Gene3D G3DSA:3.40.50.150 4 240 2.1E-31 T 29-03-2018 CVS48_RS06155 7e5174e89e34d2f16814454106f06e5d 241 PIRSF PIRSF003078 9 226 1.2E-49 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CVS48_RS06155 7e5174e89e34d2f16814454106f06e5d 241 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 24 221 24.393 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CVS48_RS05735 f840778b929b52006db67158cef56596 257 SMART SM00382 31 212 6.2E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05735 f840778b929b52006db67158cef56596 257 Gene3D G3DSA:3.40.50.300 1 219 9.9E-60 T 29-03-2018 CVS48_RS05735 f840778b929b52006db67158cef56596 257 Pfam PF00005 ABC transporter 24 162 1.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05735 f840778b929b52006db67158cef56596 257 SUPERFAMILY SSF52540 2 233 3.96E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05735 f840778b929b52006db67158cef56596 257 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS04755 36cb7ada87cc042e59ea830d631a24c2 391 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 19 357 1.2E-70 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CVS48_RS04755 36cb7ada87cc042e59ea830d631a24c2 391 SUPERFAMILY SSF51395 19 363 1.1E-96 T 29-03-2018 CVS48_RS04755 36cb7ada87cc042e59ea830d631a24c2 391 Gene3D G3DSA:3.20.20.70 18 369 8.7E-105 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS12155 2178699e31188a08651321a88e5d3289 328 Pfam PF03741 Integral membrane protein TerC family 82 289 7.5E-56 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CVS48_RS12155 2178699e31188a08651321a88e5d3289 328 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 16 321 4.7E-121 T 29-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 Gene3D G3DSA:3.30.540.10 1 149 6.8E-49 T 29-03-2018 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 SUPERFAMILY SSF56655 1 256 3.14E-81 T 29-03-2018 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 209 223 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 Gene3D G3DSA:3.40.190.80 150 261 3.9E-30 T 29-03-2018 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 4.4E-16 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 4.4E-16 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 PRINTS PR01959 SuhB family inositol monophosphatase signature 196 208 4.4E-16 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 Pfam PF00459 Inositol monophosphatase family 2 247 9.1E-60 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 3.3E-55 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 3.3E-55 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 175 196 3.3E-55 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 3.3E-55 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 3.3E-55 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS24085 8b2795c654a12bf6ff9f1c2ffba00007 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 206 230 3.3E-55 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 Gene3D G3DSA:3.30.565.10 288 446 9.6E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 SMART SM00387 336 447 7.7E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 SMART SM00388 227 293 7.8E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 401 9.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 426 9.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 387 9.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 Pfam PF00672 HAMP domain 173 223 2.2E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 SUPERFAMILY SSF158472 174 223 5.49E-5 T 29-03-2018 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 SMART SM00304 173 226 6.3E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 2 440 2.8E-124 T 29-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 229 293 7.9E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 SUPERFAMILY SSF47384 210 293 7.06E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 SUPERFAMILY SSF55874 282 443 3.01E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 Gene3D G3DSA:1.10.287.130 217 287 1.7E-13 T 29-03-2018 CVS48_RS03765 4193a5293a7f4e277cf567079cdd24ea 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 443 3.8E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS09900 0fc41c87d409a772db06a98863825ce8 347 SUPERFAMILY SSF54506 2 331 1.07E-99 T 29-03-2018 CVS48_RS09900 0fc41c87d409a772db06a98863825ce8 347 Gene3D G3DSA:3.10.310.10 151 309 5.3E-44 T 29-03-2018 CVS48_RS09900 0fc41c87d409a772db06a98863825ce8 347 Pfam PF05544 Proline racemase 8 331 3.5E-109 T 29-03-2018 IPR008794 Proline racemase family CVS48_RS09900 0fc41c87d409a772db06a98863825ce8 347 Gene3D G3DSA:3.10.310.10 1 150 4.6E-33 T 29-03-2018 CVS48_RS09900 0fc41c87d409a772db06a98863825ce8 347 PIRSF PIRSF029792 1 334 1.5E-110 T 29-03-2018 IPR008794 Proline racemase family CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 Pfam PF00128 Alpha amylase, catalytic domain 287 363 3.1E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 Gene3D G3DSA:3.20.20.80 260 629 3.9E-77 T 29-03-2018 CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 SMART SM00642 268 612 7.7E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 645 741 2.2E-20 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 SUPERFAMILY SSF51445 201 633 3.46E-114 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 Gene3D G3DSA:2.60.40.1180 640 742 4.7E-31 T 29-03-2018 CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 Gene3D G3DSA:2.60.40.10 24 123 5.3E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 Gene3D G3DSA:2.60.40.10 131 259 8.3E-29 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 SUPERFAMILY SSF51011 640 741 9.5E-32 T 29-03-2018 CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 SUPERFAMILY SSF81296 157 222 1.05E-9 T 29-03-2018 IPR014756 Immunoglobulin E-set CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 130 738 2.9E-270 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 SUPERFAMILY SSF81296 38 128 1.33E-12 T 29-03-2018 IPR014756 Immunoglobulin E-set CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 118 742 43.431 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 142 224 2.5E-21 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CVS48_RS18385 dd553c6acdea79093c24eb29752aa24c 743 PIRSF PIRSF000463 28 743 2.9E-281 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CVS48_RS12380 bd5298e8c372e90ab5cca4602e082337 274 SUPERFAMILY SSF51215 17 151 4.84E-17 T 29-03-2018 CVS48_RS12380 bd5298e8c372e90ab5cca4602e082337 274 Gene3D G3DSA:2.60.120.10 9 136 1.4E-5 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS12380 bd5298e8c372e90ab5cca4602e082337 274 SUPERFAMILY SSF46689 172 220 1.26E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS12380 bd5298e8c372e90ab5cca4602e082337 274 Gene3D G3DSA:1.10.10.60 169 223 1.0E-11 T 29-03-2018 CVS48_RS12380 bd5298e8c372e90ab5cca4602e082337 274 SUPERFAMILY SSF46689 222 267 2.15E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS12380 bd5298e8c372e90ab5cca4602e082337 274 Pfam PF12833 Helix-turn-helix domain 192 267 1.1E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS12380 bd5298e8c372e90ab5cca4602e082337 274 Pfam PF02311 AraC-like ligand binding domain 23 148 5.5E-20 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS12380 bd5298e8c372e90ab5cca4602e082337 274 SMART SM00342 186 268 7.7E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS12380 bd5298e8c372e90ab5cca4602e082337 274 Gene3D G3DSA:1.10.10.60 224 271 5.6E-12 T 29-03-2018 CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 Gene3D G3DSA:3.40.190.10 180 267 1.2E-16 T 29-03-2018 CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 Pfam PF03466 LysR substrate binding domain 96 296 3.8E-29 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 Gene3D G3DSA:1.10.10.10 10 94 6.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 SUPERFAMILY SSF53850 96 300 1.63E-29 T 29-03-2018 CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 SUPERFAMILY SSF46785 8 90 2.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 Gene3D G3DSA:3.40.190.10 97 179 1.8E-11 T 29-03-2018 CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 1.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 1.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 1.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04280 a4f68d8a66069be110a1b0869de1a27e 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 1.0E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12275 d29653bb21ae3a11ac0c06483930c21b 230 SUPERFAMILY SSF56784 5 223 1.2E-49 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS12275 d29653bb21ae3a11ac0c06483930c21b 230 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 98 190 3.7E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS12275 d29653bb21ae3a11ac0c06483930c21b 230 Gene3D G3DSA:1.10.150.240 35 77 3.6E-19 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CVS48_RS12275 d29653bb21ae3a11ac0c06483930c21b 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 189 3.0E-21 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS12275 d29653bb21ae3a11ac0c06483930c21b 230 Gene3D G3DSA:3.40.50.1000 78 230 1.2E-26 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS12275 d29653bb21ae3a11ac0c06483930c21b 230 Gene3D G3DSA:3.40.50.1000 4 34 0.27 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 287 60.117 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 Gene3D G3DSA:3.30.930.10 1 210 4.4E-89 T 29-03-2018 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 Gene3D G3DSA:1.20.58.180 212 288 3.8E-34 T 29-03-2018 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 294 2.2E-157 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 2.8E-66 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 2.8E-66 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 247 263 2.8E-66 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 2.8E-66 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 2.8E-66 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 2.8E-66 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 286 4.0E-149 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CVS48_RS01950 5a9004a28c0d67e03e260259dd04259d 303 SUPERFAMILY SSF55681 3 286 1.33E-130 T 29-03-2018 CVS48_RS00230 b5fa80e3dd625b5baa48c09eb803cb67 333 Pfam PF00005 ABC transporter 39 188 2.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS00230 b5fa80e3dd625b5baa48c09eb803cb67 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 305 5.4E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS00230 b5fa80e3dd625b5baa48c09eb803cb67 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 324 3.2E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS00230 b5fa80e3dd625b5baa48c09eb803cb67 333 SMART SM00382 47 238 3.3E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS00230 b5fa80e3dd625b5baa48c09eb803cb67 333 Gene3D G3DSA:3.40.50.300 11 331 1.4E-86 T 29-03-2018 CVS48_RS00230 b5fa80e3dd625b5baa48c09eb803cb67 333 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS00230 b5fa80e3dd625b5baa48c09eb803cb67 333 SUPERFAMILY SSF52540 47 321 3.37E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10175 3bb13653f908cedca3b9f414ed0f1f31 284 Gene3D G3DSA:3.40.50.1820 1 253 1.1E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS10175 3bb13653f908cedca3b9f414ed0f1f31 284 SUPERFAMILY SSF53474 7 252 2.04E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS10175 3bb13653f908cedca3b9f414ed0f1f31 284 Pfam PF00561 alpha/beta hydrolase fold 13 239 3.0E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS10175 3bb13653f908cedca3b9f414ed0f1f31 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 1.5E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS10175 3bb13653f908cedca3b9f414ed0f1f31 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.5E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS10175 3bb13653f908cedca3b9f414ed0f1f31 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 1.5E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 PIRSF PIRSF000350 2 562 2.1E-265 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 SUPERFAMILY SSF51905 318 458 3.81E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 SUPERFAMILY SSF51905 198 290 3.81E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 SUPERFAMILY SSF51905 101 150 3.81E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 Gene3D G3DSA:3.30.390.30 437 562 1.1E-35 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 134 144 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 TIGRFAM TIGR02053 MerA: mercury(II) reductase 101 562 9.7E-188 T 29-03-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 SUPERFAMILY SSF55424 437 560 3.44E-33 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 Gene3D G3DSA:3.50.50.60 306 434 1.0E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 101 419 1.5E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 Pfam PF00403 Heavy-metal-associated domain 6 65 1.8E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 Gene3D G3DSA:3.30.70.100 1 71 1.4E-18 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 PRINTS PR00945 Mercuric reductase class II signature 111 129 1.5E-88 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 PRINTS PR00945 Mercuric reductase class II signature 238 255 1.5E-88 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 PRINTS PR00945 Mercuric reductase class II signature 470 490 1.5E-88 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 PRINTS PR00945 Mercuric reductase class II signature 16 26 1.5E-88 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 PRINTS PR00945 Mercuric reductase class II signature 535 554 1.5E-88 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 PRINTS PR00945 Mercuric reductase class II signature 273 290 1.5E-88 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 PRINTS PR00945 Mercuric reductase class II signature 293 308 1.5E-88 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 PRINTS PR00945 Mercuric reductase class II signature 146 165 1.5E-88 T 29-03-2018 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 438 546 1.5E-28 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 SUPERFAMILY SSF55008 5 73 6.28E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 Gene3D G3DSA:3.50.50.60 257 305 7.0E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00850 a7ae2ac5423de5100681200752c343a5 562 Gene3D G3DSA:3.50.50.60 97 256 3.6E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23690 6dadb9cea2bb92695fab99baa6d72612 298 Pfam PF01904 Protein of unknown function DUF72 22 293 1.3E-56 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CVS48_RS23690 6dadb9cea2bb92695fab99baa6d72612 298 SUPERFAMILY SSF117396 1 295 3.53E-66 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CVS48_RS23690 6dadb9cea2bb92695fab99baa6d72612 298 Gene3D G3DSA:3.20.20.410 1 297 5.3E-72 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 SUPERFAMILY SSF48179 186 293 2.55E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 Gene3D G3DSA:1.10.1040.10 186 289 3.4E-22 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 SUPERFAMILY SSF51735 1 186 2.63E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 SUPERFAMILY SSF48179 414 498 1.11E-19 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 Gene3D G3DSA:3.40.50.720 2 185 7.7E-52 T 29-03-2018 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 284 3.0E-23 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 415 498 2.5E-21 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 Gene3D G3DSA:1.10.1040.10 415 505 2.4E-18 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 SUPERFAMILY SSF51971 5 46 2.94E-5 T 29-03-2018 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 SUPERFAMILY SSF51971 309 417 2.94E-5 T 29-03-2018 CVS48_RS03955 00de6e108c7bef0c7a7e76f704f41de2 507 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 184 2.8E-63 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS20575 87e39d875c1070900a8ba1f50ca37f92 211 Pfam PF13417 Glutathione S-transferase, N-terminal domain 8 79 3.1E-14 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS20575 87e39d875c1070900a8ba1f50ca37f92 211 Gene3D G3DSA:1.20.1050.10 93 199 1.5E-21 T 29-03-2018 CVS48_RS20575 87e39d875c1070900a8ba1f50ca37f92 211 Pfam PF00043 Glutathione S-transferase, C-terminal domain 122 200 2.6E-6 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS20575 87e39d875c1070900a8ba1f50ca37f92 211 SUPERFAMILY SSF52833 1 85 3.07E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS20575 87e39d875c1070900a8ba1f50ca37f92 211 SUPERFAMILY SSF47616 79 204 1.67E-25 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS20575 87e39d875c1070900a8ba1f50ca37f92 211 Gene3D G3DSA:3.40.30.10 1 92 1.9E-28 T 29-03-2018 CVS48_RS21230 4ecedb757994cda240773d52bdb99b1f 364 Gene3D G3DSA:3.40.190.10 163 307 7.3E-6 T 29-03-2018 CVS48_RS21230 4ecedb757994cda240773d52bdb99b1f 364 SUPERFAMILY SSF53850 156 322 8.36E-7 T 29-03-2018 CVS48_RS21230 4ecedb757994cda240773d52bdb99b1f 364 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 45 324 5.7E-60 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS21230 4ecedb757994cda240773d52bdb99b1f 364 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 21 3.2E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CVS48_RS21230 4ecedb757994cda240773d52bdb99b1f 364 PIRSF PIRSF039026 1 358 1.7E-124 T 29-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CVS48_RS23105 fe845e8e425c24c4ae73d96a7361258e 316 SMART SM01130 15 308 1.4E-56 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS23105 fe845e8e425c24c4ae73d96a7361258e 316 Gene3D G3DSA:3.20.20.70 8 315 4.1E-62 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS23105 fe845e8e425c24c4ae73d96a7361258e 316 Pfam PF00701 Dihydrodipicolinate synthetase family 17 302 5.3E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS23105 fe845e8e425c24c4ae73d96a7361258e 316 SUPERFAMILY SSF51569 14 310 3.56E-65 T 29-03-2018 CVS48_RS23105 fe845e8e425c24c4ae73d96a7361258e 316 PIRSF PIRSF001365 12 311 7.4E-48 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS07855 13076ab8a5e58d1f680eb8a50776d2ac 239 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 9 233 7.7E-55 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CVS48_RS07855 13076ab8a5e58d1f680eb8a50776d2ac 239 Pfam PF01168 Alanine racemase, N-terminal domain 12 233 1.5E-25 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS07855 13076ab8a5e58d1f680eb8a50776d2ac 239 Gene3D G3DSA:3.20.20.10 4 239 2.4E-68 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS07855 13076ab8a5e58d1f680eb8a50776d2ac 239 SUPERFAMILY SSF51419 5 231 2.36E-72 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS07855 13076ab8a5e58d1f680eb8a50776d2ac 239 PIRSF PIRSF004848 1 239 4.2E-74 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 271 8.9E-75 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 SUPERFAMILY SSF48179 167 275 9.01E-31 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 PIRSF PIRSF000193 4 274 1.1E-70 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 226 249 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 Gene3D G3DSA:3.40.50.720 1 164 1.8E-29 T 29-03-2018 CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 SUPERFAMILY SSF51735 7 164 2.21E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 99 4.6E-15 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 271 25.609 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 Gene3D G3DSA:1.10.3730.10 165 276 6.4E-35 T 29-03-2018 CVS48_RS19300 ea1fc32bcd078e9649d74ccd5f17a0b5 277 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 169 271 3.7E-32 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CVS48_RS05600 350cfc2397371b244c9765629ed236c6 335 Gene3D G3DSA:3.40.50.720 136 311 1.0E-39 T 29-03-2018 CVS48_RS05600 350cfc2397371b244c9765629ed236c6 335 SMART SM00829 10 325 1.6E-57 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS05600 350cfc2397371b244c9765629ed236c6 335 Gene3D G3DSA:3.90.180.10 1 135 4.1E-38 T 29-03-2018 CVS48_RS05600 350cfc2397371b244c9765629ed236c6 335 SUPERFAMILY SSF51735 113 285 2.59E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS05600 350cfc2397371b244c9765629ed236c6 335 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 327 1.5E-104 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CVS48_RS05600 350cfc2397371b244c9765629ed236c6 335 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CVS48_RS05600 350cfc2397371b244c9765629ed236c6 335 SUPERFAMILY SSF50129 1 146 2.13E-35 T 29-03-2018 IPR011032 GroES-like CVS48_RS05600 350cfc2397371b244c9765629ed236c6 335 Pfam PF00107 Zinc-binding dehydrogenase 152 272 3.0E-30 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS05600 350cfc2397371b244c9765629ed236c6 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 1.7E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 Gene3D G3DSA:3.50.30.20 1 141 5.9E-58 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 251 267 5.2E-39 T 29-03-2018 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 220 234 5.2E-39 T 29-03-2018 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 293 304 5.2E-39 T 29-03-2018 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 268 285 5.2E-39 T 29-03-2018 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 181 195 5.2E-39 T 29-03-2018 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 251 262 2.0E-10 T 29-03-2018 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 223 232 2.0E-10 T 29-03-2018 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 336 349 2.0E-10 T 29-03-2018 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 Gene3D G3DSA:3.40.50.880 142 365 3.1E-65 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 SMART SM01097 1 125 1.1E-84 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 1 361 1.1E-141 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 1 124 1.4E-49 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 365 45.793 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 SUPERFAMILY SSF52317 144 363 2.45E-61 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 Pfam PF00117 Glutamine amidotransferase class-I 184 359 2.1E-44 T 29-03-2018 IPR017926 Glutamine amidotransferase CVS48_RS13790 e0c13999fffff87391a9721f7197a5eb 365 SUPERFAMILY SSF52021 1 131 6.93E-54 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS05930 35b12f9a9622800204b9ced01fd1cfb5 113 Gene3D G3DSA:3.10.20.30 12 85 2.5E-5 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS05930 35b12f9a9622800204b9ced01fd1cfb5 113 SUPERFAMILY SSF54292 15 89 1.57E-17 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS05930 35b12f9a9622800204b9ced01fd1cfb5 113 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 14 90 7.6E-23 T 29-03-2018 CVS48_RS19595 b15b9bb84aced9808069a37ededbd54e 250 Gene3D G3DSA:3.40.190.10 149 250 5.6E-19 T 29-03-2018 CVS48_RS19595 b15b9bb84aced9808069a37ededbd54e 250 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 52 65 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CVS48_RS19595 b15b9bb84aced9808069a37ededbd54e 250 Gene3D G3DSA:3.40.190.10 19 148 3.3E-40 T 29-03-2018 CVS48_RS19595 b15b9bb84aced9808069a37ededbd54e 250 SMART SM00062 30 249 1.7E-69 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS19595 b15b9bb84aced9808069a37ededbd54e 250 SUPERFAMILY SSF53850 7 249 5.91E-76 T 29-03-2018 CVS48_RS19595 b15b9bb84aced9808069a37ededbd54e 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 248 2.8E-70 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS19595 b15b9bb84aced9808069a37ededbd54e 250 SMART SM00079 30 248 6.6E-9 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 SUPERFAMILY SSF56003 351 782 4.54E-110 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 Gene3D G3DSA:3.30.365.10 365 459 1.2E-24 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 PIRSF PIRSF036389 18 175 5.2E-26 T 29-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 PIRSF PIRSF036389 184 781 3.8E-153 T 29-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 SMART SM01008 244 330 4.7E-17 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 350 591 3.2E-29 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 639 727 1.0E-14 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 72 169 1.0E-17 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 Gene3D G3DSA:3.90.1170.50 221 364 1.2E-28 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 SUPERFAMILY SSF54665 245 331 4.45E-7 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 Gene3D G3DSA:3.30.365.10 460 625 2.0E-34 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 Gene3D G3DSA:3.30.365.10 68 220 1.7E-30 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 SUPERFAMILY SSF56003 71 271 3.42E-28 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09635 23c61231760c038bf08f984a222a5f2d 784 Gene3D G3DSA:3.30.365.10 635 784 2.2E-36 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS03120 ad60ec1fcf09058dd34e26927be3b426 398 SUPERFAMILY SSF47240 62 369 7.31E-97 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS03120 ad60ec1fcf09058dd34e26927be3b426 398 Gene3D G3DSA:1.10.620.20 42 379 9.8E-101 T 29-03-2018 CVS48_RS03120 ad60ec1fcf09058dd34e26927be3b426 398 Pfam PF00268 Ribonucleotide reductase, small chain 78 365 3.4E-85 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03120 ad60ec1fcf09058dd34e26927be3b426 398 PIRSF PIRSF000355 52 398 4.2E-132 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS16310 495e55a6677cb6993e6ca17d1150c4cf 493 ProSitePatterns PS00455 Putative AMP-binding domain signature. 144 155 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS16310 495e55a6677cb6993e6ca17d1150c4cf 493 Pfam PF00501 AMP-binding enzyme 17 382 5.6E-44 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS16310 495e55a6677cb6993e6ca17d1150c4cf 493 Gene3D G3DSA:2.30.38.10 309 375 2.3E-7 T 29-03-2018 CVS48_RS16310 495e55a6677cb6993e6ca17d1150c4cf 493 SUPERFAMILY SSF56801 15 483 1.7E-69 T 29-03-2018 CVS48_RS16310 495e55a6677cb6993e6ca17d1150c4cf 493 Gene3D G3DSA:3.30.300.30 377 489 4.7E-8 T 29-03-2018 CVS48_RS16310 495e55a6677cb6993e6ca17d1150c4cf 493 Gene3D G3DSA:3.40.50.980 11 148 6.3E-19 T 29-03-2018 CVS48_RS16310 495e55a6677cb6993e6ca17d1150c4cf 493 Gene3D G3DSA:3.40.50.980 149 308 6.8E-22 T 29-03-2018 CVS48_RS05910 c133bcc681b8ace69212beb57b85b958 311 SUPERFAMILY SSF51735 96 277 2.34E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS05910 c133bcc681b8ace69212beb57b85b958 311 SUPERFAMILY SSF52283 26 114 4.13E-7 T 29-03-2018 CVS48_RS05910 c133bcc681b8ace69212beb57b85b958 311 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 276 1.9E-43 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS05910 c133bcc681b8ace69212beb57b85b958 311 Gene3D G3DSA:3.40.50.720 10 107 2.6E-10 T 29-03-2018 CVS48_RS05910 c133bcc681b8ace69212beb57b85b958 311 Gene3D G3DSA:3.40.50.720 108 277 4.9E-42 T 29-03-2018 CVS48_RS10330 ce84217d43a31f059cc5a5ed39d60b3f 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 235 1.4E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS10330 ce84217d43a31f059cc5a5ed39d60b3f 246 SMART SM00448 5 117 6.7E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS10330 ce84217d43a31f059cc5a5ed39d60b3f 246 SUPERFAMILY SSF52172 6 135 1.85E-39 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS10330 ce84217d43a31f059cc5a5ed39d60b3f 246 Gene3D G3DSA:3.40.50.2300 6 133 1.1E-37 T 29-03-2018 CVS48_RS10330 ce84217d43a31f059cc5a5ed39d60b3f 246 Gene3D G3DSA:1.10.10.10 134 240 9.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10330 ce84217d43a31f059cc5a5ed39d60b3f 246 SMART SM00862 159 235 4.0E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS10330 ce84217d43a31f059cc5a5ed39d60b3f 246 Pfam PF00072 Response regulator receiver domain 7 118 7.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS10330 ce84217d43a31f059cc5a5ed39d60b3f 246 SUPERFAMILY SSF46894 136 236 1.33E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS10445 1cd18d7f8d75bf81025a9132830d5006 371 Pfam PF13458 Periplasmic binding protein 28 361 1.8E-50 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS10445 1cd18d7f8d75bf81025a9132830d5006 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 277 290 8.6E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS10445 1cd18d7f8d75bf81025a9132830d5006 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 8.6E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS10445 1cd18d7f8d75bf81025a9132830d5006 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 92 102 8.6E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS10445 1cd18d7f8d75bf81025a9132830d5006 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 8.6E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS10445 1cd18d7f8d75bf81025a9132830d5006 371 Gene3D G3DSA:3.40.50.2300 15 155 3.5E-26 T 29-03-2018 CVS48_RS10445 1cd18d7f8d75bf81025a9132830d5006 371 Gene3D G3DSA:3.40.50.2300 156 333 5.6E-32 T 29-03-2018 CVS48_RS10445 1cd18d7f8d75bf81025a9132830d5006 371 SUPERFAMILY SSF53822 27 370 8.75E-73 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS17445 15544ed80e163c702a8a4f0fd7529c8e 170 Gene3D G3DSA:1.10.1740.10 4 77 6.4E-16 T 29-03-2018 CVS48_RS17445 15544ed80e163c702a8a4f0fd7529c8e 170 Pfam PF08281 Sigma-70, region 4 109 160 6.3E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS17445 15544ed80e163c702a8a4f0fd7529c8e 170 Pfam PF04542 Sigma-70 region 2 12 77 3.0E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS17445 15544ed80e163c702a8a4f0fd7529c8e 170 SUPERFAMILY SSF88659 102 161 9.81E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS17445 15544ed80e163c702a8a4f0fd7529c8e 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 157 3.4E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS17445 15544ed80e163c702a8a4f0fd7529c8e 170 SUPERFAMILY SSF88946 4 74 1.49E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS17445 15544ed80e163c702a8a4f0fd7529c8e 170 Gene3D G3DSA:1.10.10.10 78 167 5.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14505 6a633157f013b36ee68ffb4deb59fb95 325 SUPERFAMILY SSF53697 126 256 6.88E-15 T 29-03-2018 CVS48_RS14505 6a633157f013b36ee68ffb4deb59fb95 325 Gene3D G3DSA:1.10.10.10 4 60 3.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14505 6a633157f013b36ee68ffb4deb59fb95 325 Gene3D G3DSA:1.10.10.10 61 95 2.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14505 6a633157f013b36ee68ffb4deb59fb95 325 Gene3D G3DSA:3.40.50.10490 123 314 2.8E-19 T 29-03-2018 CVS48_RS14505 6a633157f013b36ee68ffb4deb59fb95 325 SUPERFAMILY SSF46689 58 94 4.84E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS14505 6a633157f013b36ee68ffb4deb59fb95 325 SUPERFAMILY SSF46689 6 64 8.42E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS14505 6a633157f013b36ee68ffb4deb59fb95 325 Pfam PF01380 SIS domain 150 257 6.5E-16 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CVS48_RS22830 7f230f50ae2d7824a9717071e070a615 510 Gene3D G3DSA:3.10.105.10 287 481 1.9E-38 T 29-03-2018 CVS48_RS22830 7f230f50ae2d7824a9717071e070a615 510 SUPERFAMILY SSF53850 28 509 6.52E-131 T 29-03-2018 CVS48_RS22830 7f230f50ae2d7824a9717071e070a615 510 Gene3D G3DSA:3.40.190.10 153 286 1.1E-42 T 29-03-2018 CVS48_RS22830 7f230f50ae2d7824a9717071e070a615 510 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 432 7.1E-91 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS22830 7f230f50ae2d7824a9717071e070a615 510 Gene3D G3DSA:3.90.76.10 56 152 5.9E-30 T 29-03-2018 CVS48_RS22830 7f230f50ae2d7824a9717071e070a615 510 PIRSF PIRSF002741 1 508 1.4E-97 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS05360 770459b4f21e3a7421cf7fcda46c6ae2 508 SMART SM00490 263 344 1.5E-28 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS05360 770459b4f21e3a7421cf7fcda46c6ae2 508 SUPERFAMILY SSF52540 79 365 1.01E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05360 770459b4f21e3a7421cf7fcda46c6ae2 508 Gene3D G3DSA:3.40.50.300 12 228 1.4E-58 T 29-03-2018 CVS48_RS05360 770459b4f21e3a7421cf7fcda46c6ae2 508 Gene3D G3DSA:3.40.50.300 229 486 1.6E-42 T 29-03-2018 CVS48_RS05360 770459b4f21e3a7421cf7fcda46c6ae2 508 Pfam PF00270 DEAD/DEAH box helicase 29 199 5.8E-50 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS05360 770459b4f21e3a7421cf7fcda46c6ae2 508 Pfam PF00271 Helicase conserved C-terminal domain 240 344 2.0E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS05360 770459b4f21e3a7421cf7fcda46c6ae2 508 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 158 166 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CVS48_RS05360 770459b4f21e3a7421cf7fcda46c6ae2 508 SMART SM00487 24 227 7.2E-63 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS05360 770459b4f21e3a7421cf7fcda46c6ae2 508 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 5 486 49.452 T 29-03-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 CVS48_RS14955 69e7ba55a6f380d4b31b5f0061f96799 505 Pfam PF02321 Outer membrane efflux protein 259 435 7.0E-27 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS14955 69e7ba55a6f380d4b31b5f0061f96799 505 Pfam PF02321 Outer membrane efflux protein 45 232 2.4E-20 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS14955 69e7ba55a6f380d4b31b5f0061f96799 505 SUPERFAMILY SSF56954 44 445 1.83E-77 T 29-03-2018 CVS48_RS14955 69e7ba55a6f380d4b31b5f0061f96799 505 Gene3D G3DSA:1.20.1600.10 11 444 4.2E-61 T 29-03-2018 CVS48_RS14955 69e7ba55a6f380d4b31b5f0061f96799 505 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 42 445 1.3E-81 T 29-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 CVS48_RS18120 f0528dc76757cc34e1061b1485ad9e75 330 PIRSF PIRSF018266 5 329 6.2E-91 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS18120 f0528dc76757cc34e1061b1485ad9e75 330 Pfam PF16220 Domain of unknown function (DUF4880) 15 56 2.1E-9 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS18120 f0528dc76757cc34e1061b1485ad9e75 330 Pfam PF04773 FecR protein 124 216 6.2E-22 T 29-03-2018 IPR006860 FecR protein CVS48_RS19855 a2211ba17cdde6ee82042822fcc93eed 195 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 71 100 - T 29-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CVS48_RS19855 a2211ba17cdde6ee82042822fcc93eed 195 Gene3D G3DSA:3.30.70.240 130 189 2.8E-10 T 29-03-2018 CVS48_RS19855 a2211ba17cdde6ee82042822fcc93eed 195 Pfam PF01205 Uncharacterized protein family UPF0029 16 116 4.1E-30 T 29-03-2018 IPR001498 Impact, N-terminal CVS48_RS19855 a2211ba17cdde6ee82042822fcc93eed 195 Gene3D G3DSA:3.30.230.30 1 125 1.6E-41 T 29-03-2018 IPR001498 Impact, N-terminal CVS48_RS19855 a2211ba17cdde6ee82042822fcc93eed 195 SUPERFAMILY SSF54980 129 194 3.17E-9 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS19855 a2211ba17cdde6ee82042822fcc93eed 195 SUPERFAMILY SSF54211 4 120 4.55E-40 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS19855 a2211ba17cdde6ee82042822fcc93eed 195 Pfam PF09186 Domain of unknown function (DUF1949) 132 188 6.9E-9 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CVS48_RS09790 13a0ba62239b14bde9a01c4c19c8e87e 399 Gene3D G3DSA:1.20.1250.20 13 197 1.4E-25 T 29-03-2018 CVS48_RS09790 13a0ba62239b14bde9a01c4c19c8e87e 399 SUPERFAMILY SSF103473 11 388 5.23E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS09790 13a0ba62239b14bde9a01c4c19c8e87e 399 Gene3D G3DSA:1.20.1250.20 203 393 2.9E-13 T 29-03-2018 CVS48_RS09790 13a0ba62239b14bde9a01c4c19c8e87e 399 Pfam PF07690 Major Facilitator Superfamily 19 336 7.6E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 265 273 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 SUPERFAMILY SSF54292 211 314 1.97E-26 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 Gene3D G3DSA:3.10.20.30 218 316 7.3E-20 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 SUPERFAMILY SSF52343 99 223 2.23E-25 T 29-03-2018 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 Gene3D G3DSA:3.40.50.80 103 217 3.4E-22 T 29-03-2018 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 41 53 1.9E-42 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 53 67 1.9E-42 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 113 132 1.9E-42 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 138 147 1.9E-42 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 31 41 1.9E-42 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 77 91 1.9E-42 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 91 105 1.9E-42 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 188 196 1.9E-42 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 236 304 5.0E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 SUPERFAMILY SSF63380 7 101 1.67E-25 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS25005 31de2bbaa28393aac7ff28f918ebca55 316 Gene3D G3DSA:2.40.30.10 2 102 3.5E-15 T 29-03-2018 CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.4E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 Gene3D G3DSA:3.40.190.10 180 272 1.0E-23 T 29-03-2018 CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 Gene3D G3DSA:3.40.190.10 88 179 1.6E-16 T 29-03-2018 CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 Pfam PF03466 LysR substrate binding domain 86 295 3.1E-40 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 SUPERFAMILY SSF46785 1 83 4.44E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 SUPERFAMILY SSF53850 87 298 1.93E-33 T 29-03-2018 CVS48_RS21710 88a5fb8c62021b43c3287e7a90cfa1fb 301 Gene3D G3DSA:1.10.10.10 1 83 1.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03835 ae962d005ebc917741f13b6e833327cf 204 Gene3D G3DSA:3.40.50.150 6 196 5.5E-22 T 29-03-2018 CVS48_RS03835 ae962d005ebc917741f13b6e833327cf 204 SUPERFAMILY SSF53335 10 199 1.12E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS03835 ae962d005ebc917741f13b6e833327cf 204 Pfam PF07021 Methionine biosynthesis protein MetW 14 200 2.9E-78 T 29-03-2018 IPR010743 Methionine biosynthesis MetW CVS48_RS03835 ae962d005ebc917741f13b6e833327cf 204 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 14 201 8.7E-90 T 29-03-2018 IPR010743 Methionine biosynthesis MetW CVS48_RS01035 d0cbd7b3f63efadd9f9276d5c572ec63 158 SUPERFAMILY SSF54523 7 122 1.1E-14 T 29-03-2018 CVS48_RS01035 d0cbd7b3f63efadd9f9276d5c572ec63 158 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 6.5E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS01035 d0cbd7b3f63efadd9f9276d5c572ec63 158 Gene3D G3DSA:3.30.700.10 7 150 1.3E-9 T 29-03-2018 CVS48_RS01035 d0cbd7b3f63efadd9f9276d5c572ec63 158 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 27 1.0E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS01035 d0cbd7b3f63efadd9f9276d5c572ec63 158 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS18085 067896fc6ca07606b115e697eeb26490 304 Gene3D G3DSA:3.20.20.70 11 303 1.5E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS18085 067896fc6ca07606b115e697eeb26490 304 SUPERFAMILY SSF51569 13 302 1.57E-68 T 29-03-2018 CVS48_RS18085 067896fc6ca07606b115e697eeb26490 304 Pfam PF00701 Dihydrodipicolinate synthetase family 13 300 2.1E-54 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS18085 067896fc6ca07606b115e697eeb26490 304 SMART SM01130 11 302 3.6E-77 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS18085 067896fc6ca07606b115e697eeb26490 304 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 11 302 45.224 T 29-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CVS48_RS18085 067896fc6ca07606b115e697eeb26490 304 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 4 301 1.6E-136 T 29-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CVS48_RS18085 067896fc6ca07606b115e697eeb26490 304 PIRSF PIRSF001365 7 304 2.0E-58 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS21620 3262d363074b0d40f092e82dc51031bb 345 Gene3D G3DSA:2.60.40.10 37 142 2.3E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS21620 3262d363074b0d40f092e82dc51031bb 345 Gene3D G3DSA:3.90.215.10 143 208 8.7E-8 T 29-03-2018 IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 CVS48_RS21620 3262d363074b0d40f092e82dc51031bb 345 Pfam PF05345 Putative Ig domain 89 133 2.8E-7 T 29-03-2018 IPR008009 Putative Ig CVS48_RS21620 3262d363074b0d40f092e82dc51031bb 345 SUPERFAMILY SSF56496 148 197 3.59E-8 T 29-03-2018 IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 SMART SM00382 51 167 8.9E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 Gene3D G3DSA:1.20.272.10 253 347 9.5E-38 T 29-03-2018 CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 19 132 2.1E-12 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 Pfam PF16193 AAA C-terminal domain 191 268 1.2E-21 T 29-03-2018 IPR032423 AAA C-terminal domain CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 Gene3D G3DSA:3.40.50.300 8 155 1.7E-25 T 29-03-2018 CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 Gene3D G3DSA:1.10.8.60 156 242 1.0E-19 T 29-03-2018 CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 SUPERFAMILY SSF52540 13 237 1.69E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 Gene3D G3DSA:1.10.3710.10 349 446 4.1E-35 T 29-03-2018 CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 SUPERFAMILY SSF48019 253 434 4.7E-72 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CVS48_RS00195 dfb4dfbe625dd1df59abb385e043d4b7 446 Pfam PF12002 MgsA AAA+ ATPase C terminal 269 432 8.7E-67 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CVS48_RS13015 05c35ef570f52d6c45eb4d41e905090c 352 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 6 347 1.7E-131 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CVS48_RS13015 05c35ef570f52d6c45eb4d41e905090c 352 Gene3D G3DSA:3.40.1780.10 174 347 4.6E-64 T 29-03-2018 CVS48_RS13015 05c35ef570f52d6c45eb4d41e905090c 352 Gene3D G3DSA:3.40.1780.10 1 106 4.9E-31 T 29-03-2018 CVS48_RS13015 05c35ef570f52d6c45eb4d41e905090c 352 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 5 348 45.348 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CVS48_RS13015 05c35ef570f52d6c45eb4d41e905090c 352 SUPERFAMILY SSF111337 6 347 2.35E-129 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CVS48_RS13015 05c35ef570f52d6c45eb4d41e905090c 352 Pfam PF02547 Queuosine biosynthesis protein 7 347 6.9E-131 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 SMART SM01130 7 291 4.7E-87 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 11 280 4.7E-65 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 43 60 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 4.6E-17 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 4.6E-17 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 4.6E-17 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 4.6E-17 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 Gene3D G3DSA:3.20.20.70 2 292 6.7E-74 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 Pfam PF00701 Dihydrodipicolinate synthetase family 8 281 1.0E-52 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 PIRSF PIRSF001365 3 297 1.1E-67 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 7 289 43.166 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 SUPERFAMILY SSF51569 4 290 6.59E-76 T 29-03-2018 CVS48_RS06905 d6175afcdf5826ae6b71aeb8476b754b 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 639 657 6.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 606 620 6.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 624 634 6.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 663 676 6.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 561 678 6.6E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 SMART SM00448 705 817 8.2E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 Gene3D G3DSA:3.30.565.10 497 678 3.8E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 SMART SM00388 451 514 3.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 Pfam PF07695 7TM diverse intracellular signalling 201 376 2.4E-13 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 SUPERFAMILY SSF47384 436 509 9.22E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 SMART SM00387 560 679 2.4E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 Gene3D G3DSA:3.40.50.2300 698 904 3.1E-21 T 29-03-2018 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 Pfam PF07696 7TMR-DISM extracellular 2 60 187 9.5E-23 T 29-03-2018 IPR011622 7TM-DISM receptor, extracellular domain, type 2 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 SUPERFAMILY SSF55874 516 677 3.54E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 SUPERFAMILY SSF52172 703 830 2.7E-23 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 Pfam PF00072 Response regulator receiver domain 709 816 2.3E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 Gene3D G3DSA:1.10.287.130 439 496 1.3E-15 T 29-03-2018 CVS48_RS11505 8f6e75e8ad084c9b445e57410107ec98 906 Pfam PF00512 His Kinase A (phospho-acceptor) domain 452 509 5.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS26300 b4795ae6f5810231fb1d5497d03cca5f 499 Gene3D G3DSA:3.20.20.140 90 410 6.4E-38 T 29-03-2018 CVS48_RS26300 b4795ae6f5810231fb1d5497d03cca5f 499 Gene3D G3DSA:2.30.40.10 3 89 3.3E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS26300 b4795ae6f5810231fb1d5497d03cca5f 499 SUPERFAMILY SSF51338 395 414 8.35E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS26300 b4795ae6f5810231fb1d5497d03cca5f 499 SUPERFAMILY SSF51338 20 63 8.35E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS26300 b4795ae6f5810231fb1d5497d03cca5f 499 SUPERFAMILY SSF51556 92 394 1.46E-54 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS26300 b4795ae6f5810231fb1d5497d03cca5f 499 SUPERFAMILY SSF51338 354 472 8.28E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS26300 b4795ae6f5810231fb1d5497d03cca5f 499 Pfam PF01979 Amidohydrolase family 106 444 1.1E-32 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS14825 9ad644cc905f53a012334f9a780538c8 284 Gene3D G3DSA:3.90.1210.10 54 115 3.8E-12 T 29-03-2018 CVS48_RS14825 9ad644cc905f53a012334f9a780538c8 284 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 124 223 4.6E-17 T 29-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain CVS48_RS14825 9ad644cc905f53a012334f9a780538c8 284 SMART SM00858 52 116 1.7E-5 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS14825 9ad644cc905f53a012334f9a780538c8 284 Pfam PF08666 SAF domain 55 115 5.4E-6 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS14825 9ad644cc905f53a012334f9a780538c8 284 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 17 264 1.8E-39 T 29-03-2018 IPR017592 Pilus assembly, Flp-type CpaB CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 375 3.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 3.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 389 3.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 279 2.9E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 SMART SM00304 162 214 4.3E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 SMART SM00388 215 280 1.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 Gene3D G3DSA:3.30.565.10 287 435 2.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 431 9.4E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 Gene3D G3DSA:1.10.287.130 205 276 1.0E-8 T 29-03-2018 CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 SUPERFAMILY SSF55874 270 432 1.57E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 SMART SM00387 325 435 6.2E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11405 7bd7391893cf40ee732c245642cf1530 435 SUPERFAMILY SSF47384 199 279 1.9E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS04110 482b81ea72dca3a34ab23b1b83f8ca5e 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 1.3E-27 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CVS48_RS04110 482b81ea72dca3a34ab23b1b83f8ca5e 156 Gene3D G3DSA:1.20.5.620 7 122 5.1E-5 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CVS48_RS04110 482b81ea72dca3a34ab23b1b83f8ca5e 156 SUPERFAMILY SSF81573 67 121 4.18E-7 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CVS48_RS04110 482b81ea72dca3a34ab23b1b83f8ca5e 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 11.435 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CVS48_RS04110 482b81ea72dca3a34ab23b1b83f8ca5e 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 1.4E-38 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CVS48_RS13005 74ef052c30be71c45aef22198e35c5b7 114 Pfam PF02699 Preprotein translocase subunit 24 103 7.6E-31 T 29-03-2018 IPR003849 Preprotein translocase YajC CVS48_RS13005 74ef052c30be71c45aef22198e35c5b7 114 SMART SM01323 20 106 2.2E-43 T 29-03-2018 IPR003849 Preprotein translocase YajC CVS48_RS13005 74ef052c30be71c45aef22198e35c5b7 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 4.1E-17 T 29-03-2018 IPR003849 Preprotein translocase YajC CVS48_RS13005 74ef052c30be71c45aef22198e35c5b7 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 60 78 4.1E-17 T 29-03-2018 IPR003849 Preprotein translocase YajC CVS48_RS13005 74ef052c30be71c45aef22198e35c5b7 114 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 106 7.6E-25 T 29-03-2018 IPR003849 Preprotein translocase YajC CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 SMART SM00729 137 362 2.4E-54 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 Pfam PF00919 Uncharacterized protein family UPF0004 5 93 4.5E-21 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 SUPERFAMILY SSF102114 117 367 1.09E-53 T 29-03-2018 CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 4 437 62.913 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 Gene3D G3DSA:2.40.50.140 377 438 2.1E-24 T 29-03-2018 CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 Gene3D G3DSA:3.80.30.20 134 376 3.9E-46 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 Pfam PF04055 Radical SAM superfamily 143 319 3.5E-29 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 141 161 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 5 435 1.7E-184 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CVS48_RS07925 ef7375966c2d7d80a61a0afa12b2f848 438 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 435 5.8E-105 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CVS48_RS07585 160f199a92b4695a3db4002f2c7f27c2 299 Gene3D G3DSA:3.40.190.10 181 263 4.4E-4 T 29-03-2018 CVS48_RS07585 160f199a92b4695a3db4002f2c7f27c2 299 Pfam PF03466 LysR substrate binding domain 97 291 6.6E-12 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS07585 160f199a92b4695a3db4002f2c7f27c2 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 3.4E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS07585 160f199a92b4695a3db4002f2c7f27c2 299 SUPERFAMILY SSF46785 3 109 1.74E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07585 160f199a92b4695a3db4002f2c7f27c2 299 Gene3D G3DSA:1.10.10.10 1 87 2.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07585 160f199a92b4695a3db4002f2c7f27c2 299 Gene3D G3DSA:3.40.190.10 94 180 8.4E-39 T 29-03-2018 CVS48_RS07585 160f199a92b4695a3db4002f2c7f27c2 299 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 3 294 1.6E-114 T 29-03-2018 IPR017685 HTH-type transcriptional regulator ArgP CVS48_RS07585 160f199a92b4695a3db4002f2c7f27c2 299 SUPERFAMILY SSF53850 91 293 2.71E-19 T 29-03-2018 CVS48_RS09255 d41e2c52857b79d668f772e2289316f9 622 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS09255 d41e2c52857b79d668f772e2289316f9 622 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 612 1.8E-251 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS09255 d41e2c52857b79d668f772e2289316f9 622 SUPERFAMILY SSF143975 3 423 1.44E-131 T 29-03-2018 CVS48_RS09255 d41e2c52857b79d668f772e2289316f9 622 Pfam PF00920 Dehydratase family 34 609 1.1E-217 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS09255 d41e2c52857b79d668f772e2289316f9 622 Gene3D G3DSA:3.40.50.2300 53 188 2.4E-4 T 29-03-2018 CVS48_RS09255 d41e2c52857b79d668f772e2289316f9 622 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 612 44.777 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS09255 d41e2c52857b79d668f772e2289316f9 622 Gene3D G3DSA:2.120.10.30 249 489 0.0013 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS09255 d41e2c52857b79d668f772e2289316f9 622 SUPERFAMILY SSF52016 424 615 3.84E-61 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS09255 d41e2c52857b79d668f772e2289316f9 622 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 512 523 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS21045 f3b5ff2fdecb374e386bb4040d619d51 391 Pfam PF02627 Carboxymuconolactone decarboxylase family 252 331 4.7E-13 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS21045 f3b5ff2fdecb374e386bb4040d619d51 391 TIGRFAM TIGR04029 CMD_Avi_7170: CMD domain protein, Avi_7170 family 13 167 5.9E-31 T 29-03-2018 IPR023982 Conserved hypothetical protein CHP04029, CMD-like CVS48_RS21045 f3b5ff2fdecb374e386bb4040d619d51 391 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 270 299 3.5E-9 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS21045 f3b5ff2fdecb374e386bb4040d619d51 391 Gene3D G3DSA:1.20.1290.10 25 177 5.1E-15 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS21045 f3b5ff2fdecb374e386bb4040d619d51 391 SUPERFAMILY SSF69118 208 386 1.09E-41 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS21045 f3b5ff2fdecb374e386bb4040d619d51 391 Gene3D G3DSA:1.20.1290.10 224 390 1.0E-24 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS21045 f3b5ff2fdecb374e386bb4040d619d51 391 SUPERFAMILY SSF69118 26 166 1.09E-19 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS21045 f3b5ff2fdecb374e386bb4040d619d51 391 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 214 386 1.4E-62 T 29-03-2018 IPR010195 Uncharacterised peroxidase-related CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 3.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 3.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 3.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 250 5.9E-62 T 29-03-2018 CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 Gene3D G3DSA:3.40.50.720 1 251 3.4E-75 T 29-03-2018 CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 195 7.2E-6 T 29-03-2018 CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 SUPERFAMILY SSF51735 12 250 1.42E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15830 d6d1bbe6cfe6e12b2d5fe7906f533636 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 SUPERFAMILY SSF48179 483 586 3.06E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 Gene3D G3DSA:3.40.50.720 258 482 1.2E-60 T 29-03-2018 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 Gene3D G3DSA:3.90.226.10 1 257 1.4E-61 T 29-03-2018 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 484 577 5.8E-23 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 615 698 1.1E-7 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 303 479 6.9E-60 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 SUPERFAMILY SSF48179 609 700 2.13E-22 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 SUPERFAMILY SSF51735 301 479 4.05E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 SUPERFAMILY SSF52096 13 294 1.02E-66 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 Gene3D G3DSA:1.10.1040.10 483 582 1.3E-23 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 Gene3D G3DSA:1.10.1040.10 608 703 1.4E-17 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 215 3.5E-38 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS20600 dc68a63367c02dc08cbbfd97911d9a6c 707 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 PIRSF PIRSF002560 1 157 2.9E-73 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 PRINTS PR00601 Bacterioferritin signature 44 64 2.4E-66 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 PRINTS PR00601 Bacterioferritin signature 3 22 2.4E-66 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 PRINTS PR00601 Bacterioferritin signature 128 149 2.4E-66 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 PRINTS PR00601 Bacterioferritin signature 86 106 2.4E-66 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 PRINTS PR00601 Bacterioferritin signature 23 43 2.4E-66 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 PRINTS PR00601 Bacterioferritin signature 65 85 2.4E-66 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 PRINTS PR00601 Bacterioferritin signature 107 127 2.4E-66 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 SUPERFAMILY SSF47240 1 154 1.05E-53 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 Gene3D G3DSA:1.20.5.420 85 138 5.1E-22 T 29-03-2018 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 Pfam PF00210 Ferritin-like domain 9 143 1.5E-38 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 Gene3D G3DSA:1.20.1260.10 1 78 2.7E-16 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 2.4E-75 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS05380 c2c76957129e494f0293cc31773dba30 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 Gene3D G3DSA:2.10.109.10 86 293 3.5E-58 T 29-03-2018 CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 SUPERFAMILY SSF51306 88 290 6.02E-68 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 ProSitePatterns PS00760 Signal peptidases I lysine active site. 156 168 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 154 166 7.2E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 244 263 7.2E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 90 106 7.2E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 ProSitePatterns PS00501 Signal peptidases I serine active site. 99 106 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 75 284 5.8E-51 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 Pfam PF10502 Signal peptidase, peptidase S26 243 281 5.3E-7 T 29-03-2018 IPR019533 Peptidase S26 CVS48_RS28270 56db91b74147a967cb4174c7ca0324ab 294 Pfam PF00717 Peptidase S24-like 96 178 5.1E-22 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CVS48_RS15060 d3b0caea208651736fa57f5d1a4aafe9 297 SUPERFAMILY SSF103481 55 154 2.62E-13 T 29-03-2018 CVS48_RS15060 d3b0caea208651736fa57f5d1a4aafe9 297 Pfam PF00892 EamA-like transporter family 18 151 1.1E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS15060 d3b0caea208651736fa57f5d1a4aafe9 297 Pfam PF00892 EamA-like transporter family 160 290 2.4E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS15060 d3b0caea208651736fa57f5d1a4aafe9 297 SUPERFAMILY SSF103481 201 295 3.92E-12 T 29-03-2018 CVS48_RS28235 cb2f846fcff99a012bebb3c7695e0166 318 PIRSF PIRSF017082 1 318 5.7E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS28235 cb2f846fcff99a012bebb3c7695e0166 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 315 1.2E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS28235 cb2f846fcff99a012bebb3c7695e0166 318 SUPERFAMILY SSF53850 108 280 7.19E-13 T 29-03-2018 CVS48_RS28235 cb2f846fcff99a012bebb3c7695e0166 318 Gene3D G3DSA:3.40.190.10 120 317 1.8E-11 T 29-03-2018 CVS48_RS11420 b808ffd9d28156191c5ecdacf3acda5f 385 Gene3D G3DSA:3.40.50.2000 174 352 1.5E-37 T 29-03-2018 CVS48_RS11420 b808ffd9d28156191c5ecdacf3acda5f 385 Pfam PF00534 Glycosyl transferases group 1 184 345 7.0E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS11420 b808ffd9d28156191c5ecdacf3acda5f 385 Pfam PF13439 Glycosyltransferase Family 4 13 155 8.0E-14 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS11420 b808ffd9d28156191c5ecdacf3acda5f 385 SUPERFAMILY SSF53756 4 369 1.49E-60 T 29-03-2018 CVS48_RS11420 b808ffd9d28156191c5ecdacf3acda5f 385 Gene3D G3DSA:3.40.50.2000 1 173 4.7E-11 T 29-03-2018 CVS48_RS04310 5061127fc3f2edee710c07d0e4c199c0 310 PIRSF PIRSF018296 1 310 6.6E-99 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 CVS48_RS04310 5061127fc3f2edee710c07d0e4c199c0 310 Gene3D G3DSA:3.90.1670.10 19 309 2.0E-93 T 29-03-2018 IPR024064 FdhE-like CVS48_RS04310 5061127fc3f2edee710c07d0e4c199c0 310 SUPERFAMILY SSF144020 22 307 6.02E-83 T 29-03-2018 IPR024064 FdhE-like CVS48_RS04310 5061127fc3f2edee710c07d0e4c199c0 310 Hamap MF_00611 Protein FdhE [fdhE]. 2 307 34.81 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 CVS48_RS04310 5061127fc3f2edee710c07d0e4c199c0 310 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 3 304 3.6E-83 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 CVS48_RS04310 5061127fc3f2edee710c07d0e4c199c0 310 Pfam PF04216 Protein involved in formate dehydrogenase formation 18 305 7.3E-109 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 CVS48_RS26595 c48b0f2259fb54354a4bfc8261ffa091 203 Pfam PF13410 Glutathione S-transferase, C-terminal domain 120 184 1.4E-6 T 29-03-2018 CVS48_RS26595 c48b0f2259fb54354a4bfc8261ffa091 203 Gene3D G3DSA:3.40.30.10 1 89 6.3E-22 T 29-03-2018 CVS48_RS26595 c48b0f2259fb54354a4bfc8261ffa091 203 SUPERFAMILY SSF52833 1 101 3.66E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS26595 c48b0f2259fb54354a4bfc8261ffa091 203 Gene3D G3DSA:1.20.1050.10 90 203 8.9E-22 T 29-03-2018 CVS48_RS26595 c48b0f2259fb54354a4bfc8261ffa091 203 SUPERFAMILY SSF47616 69 200 5.43E-24 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS26595 c48b0f2259fb54354a4bfc8261ffa091 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 1.4E-18 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS03580 d3c3837c0ddbb6920b065bb0c3b4031a 284 Gene3D G3DSA:3.40.50.620 1 171 9.5E-68 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS03580 d3c3837c0ddbb6920b065bb0c3b4031a 284 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 278 2.9E-90 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CVS48_RS03580 d3c3837c0ddbb6920b065bb0c3b4031a 284 Pfam PF02569 Pantoate-beta-alanine ligase 2 278 2.1E-95 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CVS48_RS03580 d3c3837c0ddbb6920b065bb0c3b4031a 284 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 69 3.9E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CVS48_RS03580 d3c3837c0ddbb6920b065bb0c3b4031a 284 SUPERFAMILY SSF52374 2 281 4.15E-95 T 29-03-2018 CVS48_RS03580 d3c3837c0ddbb6920b065bb0c3b4031a 284 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 37.552 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CVS48_RS03580 d3c3837c0ddbb6920b065bb0c3b4031a 284 Gene3D G3DSA:3.30.1300.10 173 284 9.2E-32 T 29-03-2018 CVS48_RS12670 3ec3eb47ab54672d06fe3a0291ba377e 242 SMART SM00895 95 221 5.6E-12 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS12670 3ec3eb47ab54672d06fe3a0291ba377e 242 SUPERFAMILY SSF48008 91 228 3.66E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS12670 3ec3eb47ab54672d06fe3a0291ba377e 242 Gene3D G3DSA:1.20.120.530 82 239 1.6E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS12670 3ec3eb47ab54672d06fe3a0291ba377e 242 Pfam PF07729 FCD domain 96 220 9.6E-16 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS12670 3ec3eb47ab54672d06fe3a0291ba377e 242 Gene3D G3DSA:1.10.10.10 11 81 5.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12670 3ec3eb47ab54672d06fe3a0291ba377e 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 85 3.1E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS12670 3ec3eb47ab54672d06fe3a0291ba377e 242 SUPERFAMILY SSF46785 21 89 6.95E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12670 3ec3eb47ab54672d06fe3a0291ba377e 242 SMART SM00345 27 85 5.7E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS12540 1b23f2477aff7ac6e05b16476ffa130b 290 Gene3D G3DSA:3.90.1140.10 40 283 1.3E-11 T 29-03-2018 CVS48_RS02455 c6d03162a0ff07a814a6fd422dc334c6 274 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 7 253 24.586 T 29-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 CVS48_RS02455 c6d03162a0ff07a814a6fd422dc334c6 274 Pfam PF03799 Cell division protein FtsQ 114 245 8.1E-24 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB CVS48_RS02455 c6d03162a0ff07a814a6fd422dc334c6 274 Pfam PF08478 POTRA domain, FtsQ-type 53 110 2.6E-14 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 202.149 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 Gene3D G3DSA:3.30.980.10 551 710 1.8E-41 T 29-03-2018 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 SUPERFAMILY SSF55186 550 708 3.14E-48 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 853 0.0 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 Pfam PF01411 tRNA synthetases class II (A) 5 552 4.1E-221 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 651 693 3.3E-17 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 SMART SM00863 651 693 1.1E-20 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 SUPERFAMILY SSF55681 2 251 8.2E-108 T 29-03-2018 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 Gene3D G3DSA:2.40.30.10 449 508 0.27 T 29-03-2018 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 SUPERFAMILY SSF50447 451 550 1.85E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 Pfam PF02272 DHHA1 domain 731 870 5.8E-24 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 Gene3D G3DSA:3.30.930.10 1 248 2.3E-116 T 29-03-2018 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 5.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 5.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 5.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 5.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 232 245 5.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CVS48_RS14610 0b89b07ccc01be91ba6b55ea95cf2341 874 SUPERFAMILY SSF101353 252 442 4.84E-59 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CVS48_RS05275 64d6d8ab077d8382ee83d510b8347f82 321 SUPERFAMILY SSF53850 110 284 1.19E-10 T 29-03-2018 CVS48_RS05275 64d6d8ab077d8382ee83d510b8347f82 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 1.4E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS05275 64d6d8ab077d8382ee83d510b8347f82 321 Gene3D G3DSA:3.40.190.10 123 253 1.3E-7 T 29-03-2018 CVS48_RS05275 64d6d8ab077d8382ee83d510b8347f82 321 PIRSF PIRSF017082 1 320 7.4E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 6.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 6.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 6.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.2E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 1.2E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 1.2E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.2E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 SUPERFAMILY SSF51735 1 206 2.93E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 Gene3D G3DSA:3.40.50.720 1 223 4.8E-45 T 29-03-2018 CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS16280 2473e354f18c90db6efffbcfa03ad3b5 230 Pfam PF00106 short chain dehydrogenase 7 185 9.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22335 0d9dc4b3166b5eac95ac7c443db9514d 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 104 130 1.3E-36 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CVS48_RS22335 0d9dc4b3166b5eac95ac7c443db9514d 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 372 391 1.3E-36 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CVS48_RS22335 0d9dc4b3166b5eac95ac7c443db9514d 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 132 151 1.3E-36 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CVS48_RS22335 0d9dc4b3166b5eac95ac7c443db9514d 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 157 178 1.3E-36 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CVS48_RS22335 0d9dc4b3166b5eac95ac7c443db9514d 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 209 232 1.3E-36 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CVS48_RS22335 0d9dc4b3166b5eac95ac7c443db9514d 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 311 330 1.3E-36 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CVS48_RS22335 0d9dc4b3166b5eac95ac7c443db9514d 429 Pfam PF01566 Natural resistance-associated macrophage protein 45 401 1.6E-96 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 25 718 2.9E-301 T 29-03-2018 IPR017750 ATPase, type I secretion system CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 Gene3D G3DSA:3.40.50.300 481 719 2.0E-63 T 29-03-2018 CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 Pfam PF00664 ABC transporter transmembrane region 178 435 2.0E-21 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 Gene3D G3DSA:1.20.1560.10 154 479 2.0E-32 T 29-03-2018 CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 Gene3D G3DSA:3.90.70.10 15 153 1.6E-15 T 29-03-2018 CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 Pfam PF00005 ABC transporter 506 654 6.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 Pfam PF03412 Peptidase C39 family 24 144 2.0E-5 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 SUPERFAMILY SSF52540 479 713 9.3E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 SUPERFAMILY SSF90123 162 474 1.83E-52 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS14945 6d5dd84d2fd01ce23a271cf8082c38c8 724 SMART SM00382 515 701 2.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08570 cbd1bd70f9659e95043c20925a203561 528 Pfam PF16989 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ 239 485 1.6E-51 T 29-03-2018 IPR017739 Type VI secretion system-associated, VCA0119 CVS48_RS08570 cbd1bd70f9659e95043c20925a203561 528 TIGRFAM TIGR03362 VI_chp_7: type VI secretion-associated protein, VC_A0119 family 11 488 2.8E-94 T 29-03-2018 IPR017739 Type VI secretion system-associated, VCA0119 CVS48_RS08570 cbd1bd70f9659e95043c20925a203561 528 Pfam PF06812 ImpA, N-terminal, type VI secretion system 13 125 1.8E-25 T 29-03-2018 IPR010657 ImpA, N-terminal CVS48_RS13650 67216515ad3adafd90885302709d711f 129 Gene3D G3DSA:1.10.3990.20 11 95 7.9E-34 T 29-03-2018 CVS48_RS13650 67216515ad3adafd90885302709d711f 129 Pfam PF13467 Ribbon-helix-helix domain 16 82 1.0E-25 T 29-03-2018 IPR027373 Ribbon-helix-helix domain CVS48_RS29050 a98c84301b36ae7148a1c63569b72bf6 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 42 314 1.1E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS29050 a98c84301b36ae7148a1c63569b72bf6 319 SUPERFAMILY SSF53850 82 276 1.28E-12 T 29-03-2018 CVS48_RS29050 a98c84301b36ae7148a1c63569b72bf6 319 Gene3D G3DSA:3.40.190.10 117 228 1.3E-12 T 29-03-2018 CVS48_RS29050 a98c84301b36ae7148a1c63569b72bf6 319 PIRSF PIRSF017082 1 318 4.3E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS27665 345a464736d45d4b14752187f9234066 178 Pfam PF10634 Fe2+ transport protein 20 171 2.5E-70 T 29-03-2018 IPR018470 Periplasmic metal-binding protein Tp34-type CVS48_RS27665 345a464736d45d4b14752187f9234066 178 PIRSF PIRSF017018 1 178 3.6E-85 T 29-03-2018 IPR018470 Periplasmic metal-binding protein Tp34-type CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 Pfam PF00384 Molybdopterin oxidoreductase 104 512 3.2E-82 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 SMART SM00926 26 80 1.4E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 Gene3D G3DSA:2.20.25.90 21 79 2.6E-20 T 29-03-2018 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 Pfam PF01568 Molydopterin dinucleotide binding domain 611 717 1.5E-25 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 Gene3D G3DSA:3.40.50.740 80 265 3.0E-45 T 29-03-2018 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 SUPERFAMILY SSF50692 599 736 1.04E-38 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 Gene3D G3DSA:3.40.50.740 266 568 8.8E-84 T 29-03-2018 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 PIRSF PIRSF036643 9 742 3.6E-161 T 29-03-2018 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 Gene3D G3DSA:2.40.40.20 569 726 2.7E-39 T 29-03-2018 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 Pfam PF04324 BFD-like [2Fe-2S] binding domain 860 908 3.2E-7 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 28 78 2.3E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 SUPERFAMILY SSF53706 25 594 1.31E-187 T 29-03-2018 CVS48_RS13060 036e20e6b7afc805f2d9a14ed8d6ed75 922 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 31 48 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CVS48_RS22450 d777752ef5d437439d3bd400f2a76088 455 Gene3D G3DSA:2.40.50.140 14 112 3.1E-6 T 29-03-2018 CVS48_RS22450 d777752ef5d437439d3bd400f2a76088 455 Pfam PF02601 Exonuclease VII, large subunit 133 442 8.9E-91 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CVS48_RS22450 d777752ef5d437439d3bd400f2a76088 455 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 14 446 27.573 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CVS48_RS22450 d777752ef5d437439d3bd400f2a76088 455 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 18 445 7.3E-137 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CVS48_RS22450 d777752ef5d437439d3bd400f2a76088 455 Pfam PF13742 OB-fold nucleic acid binding domain 17 109 4.2E-30 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CVS48_RS01390 573dfc1b440c4e929a2eeb1af7dd2d94 447 Gene3D G3DSA:3.40.350.10 2 177 1.9E-42 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CVS48_RS01390 573dfc1b440c4e929a2eeb1af7dd2d94 447 Pfam PF05195 Aminopeptidase P, N-terminal domain 11 128 1.2E-33 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CVS48_RS01390 573dfc1b440c4e929a2eeb1af7dd2d94 447 SUPERFAMILY SSF55920 180 445 3.27E-82 T 29-03-2018 IPR000994 Peptidase M24 CVS48_RS01390 573dfc1b440c4e929a2eeb1af7dd2d94 447 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 353 365 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CVS48_RS01390 573dfc1b440c4e929a2eeb1af7dd2d94 447 Gene3D G3DSA:3.90.230.10 178 447 1.1E-81 T 29-03-2018 CVS48_RS01390 573dfc1b440c4e929a2eeb1af7dd2d94 447 SUPERFAMILY SSF53092 6 179 2.22E-46 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CVS48_RS01390 573dfc1b440c4e929a2eeb1af7dd2d94 447 Pfam PF00557 Metallopeptidase family M24 186 424 1.3E-60 T 29-03-2018 IPR000994 Peptidase M24 CVS48_RS01390 573dfc1b440c4e929a2eeb1af7dd2d94 447 SMART SM01011 6 141 3.0E-58 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CVS48_RS09380 a94d1b43c6d77ff0e38507c6e7b15864 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 331 1.4E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09380 a94d1b43c6d77ff0e38507c6e7b15864 338 Gene3D G3DSA:3.40.190.10 136 266 7.0E-13 T 29-03-2018 CVS48_RS09380 a94d1b43c6d77ff0e38507c6e7b15864 338 PIRSF PIRSF017082 1 337 1.1E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09380 a94d1b43c6d77ff0e38507c6e7b15864 338 SUPERFAMILY SSF53850 123 298 4.27E-13 T 29-03-2018 CVS48_RS06975 ed8c4181af78d6aae09cee6c28d7bcaa 353 SUPERFAMILY SSF51735 1 335 1.54E-89 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS06975 ed8c4181af78d6aae09cee6c28d7bcaa 353 Gene3D G3DSA:3.40.50.720 1 236 4.1E-55 T 29-03-2018 CVS48_RS06975 ed8c4181af78d6aae09cee6c28d7bcaa 353 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 337 2.4E-149 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CVS48_RS06975 ed8c4181af78d6aae09cee6c28d7bcaa 353 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 1.4E-98 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS06975 ed8c4181af78d6aae09cee6c28d7bcaa 353 Gene3D G3DSA:3.90.25.10 237 334 6.9E-30 T 29-03-2018 CVS48_RS12945 68e762df096147387b1ded4539f32b4f 351 Gene3D G3DSA:3.20.20.100 5 330 1.5E-87 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS12945 68e762df096147387b1ded4539f32b4f 351 SUPERFAMILY SSF51430 8 325 9.04E-89 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS12945 68e762df096147387b1ded4539f32b4f 351 Pfam PF00248 Aldo/keto reductase family 21 326 2.4E-65 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS25115 f6470704945bf934585243fe07c57210 268 Pfam PF01614 Bacterial transcriptional regulator 143 220 2.7E-5 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS25115 f6470704945bf934585243fe07c57210 268 Gene3D G3DSA:1.10.10.10 18 80 6.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25115 f6470704945bf934585243fe07c57210 268 SMART SM00346 19 109 1.4E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS25115 f6470704945bf934585243fe07c57210 268 Pfam PF09339 IclR helix-turn-helix domain 21 71 2.4E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS25115 f6470704945bf934585243fe07c57210 268 SUPERFAMILY SSF46785 21 91 2.42E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25115 f6470704945bf934585243fe07c57210 268 SUPERFAMILY SSF55781 86 262 1.18E-23 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS25115 f6470704945bf934585243fe07c57210 268 Gene3D G3DSA:3.30.450.40 87 268 9.0E-26 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS28475 6ffe737791121f0731ccfa7a15fecaa1 404 Gene3D G3DSA:3.40.50.2300 165 311 1.7E-28 T 29-03-2018 CVS48_RS28475 6ffe737791121f0731ccfa7a15fecaa1 404 Gene3D G3DSA:3.40.50.2300 16 164 5.1E-25 T 29-03-2018 CVS48_RS28475 6ffe737791121f0731ccfa7a15fecaa1 404 Pfam PF13458 Periplasmic binding protein 32 367 3.9E-90 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS28475 6ffe737791121f0731ccfa7a15fecaa1 404 SUPERFAMILY SSF53822 32 402 1.3E-90 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS04725 24edf5e6e01cffe6d6c02fd6205889f7 691 SUPERFAMILY SSF53756 249 667 1.1E-49 T 29-03-2018 CVS48_RS04725 24edf5e6e01cffe6d6c02fd6205889f7 691 Pfam PF00534 Glycosyl transferases group 1 485 649 9.5E-24 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS04725 24edf5e6e01cffe6d6c02fd6205889f7 691 Gene3D G3DSA:3.40.50.2000 482 654 1.9E-30 T 29-03-2018 CVS48_RS04725 24edf5e6e01cffe6d6c02fd6205889f7 691 Gene3D G3DSA:1.25.40.10 25 204 7.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04725 24edf5e6e01cffe6d6c02fd6205889f7 691 Gene3D G3DSA:3.40.50.2000 240 481 9.8E-8 T 29-03-2018 CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 Gene3D G3DSA:1.20.200.10 104 371 1.7E-80 T 29-03-2018 CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 SMART SM00998 364 443 4.7E-30 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 1.9E-25 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 1.9E-25 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 1.9E-25 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 PRINTS PR00149 Fumarate lyase superfamily signature 101 119 1.9E-25 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 Gene3D G3DSA:1.10.275.10 4 103 3.3E-17 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 Gene3D G3DSA:1.10.40.30 372 443 9.4E-25 T 29-03-2018 CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 SUPERFAMILY SSF48557 11 444 1.29E-118 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 Pfam PF00206 Lyase 66 299 1.1E-47 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 PRINTS PR00145 Argininosuccinate lyase family signature 141 161 3.3E-12 T 29-03-2018 CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 3.3E-12 T 29-03-2018 CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 PRINTS PR00145 Argininosuccinate lyase family signature 231 255 3.3E-12 T 29-03-2018 CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 PRINTS PR00145 Argininosuccinate lyase family signature 100 122 3.3E-12 T 29-03-2018 CVS48_RS11815 936b98db6c50c7a4b59d3cfcba190c76 451 Pfam PF10397 Adenylosuccinate lyase C-terminus 365 442 2.2E-22 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS11085 ae3184cc82337515603552fe919afd19 469 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 456 3.9E-139 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS11085 ae3184cc82337515603552fe919afd19 469 PIRSF PIRSF006066 1 248 2.7E-68 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS11085 ae3184cc82337515603552fe919afd19 469 PIRSF PIRSF006066 243 467 4.2E-69 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS13585 aa86f94e9e69e922c68404d3e6e70b83 501 Gene3D G3DSA:3.90.76.10 47 145 2.4E-16 T 29-03-2018 CVS48_RS13585 aa86f94e9e69e922c68404d3e6e70b83 501 PIRSF PIRSF002741 2 500 8.2E-72 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS13585 aa86f94e9e69e922c68404d3e6e70b83 501 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 65 415 3.8E-69 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS13585 aa86f94e9e69e922c68404d3e6e70b83 501 Gene3D G3DSA:3.10.105.10 278 472 2.6E-37 T 29-03-2018 CVS48_RS13585 aa86f94e9e69e922c68404d3e6e70b83 501 Gene3D G3DSA:3.40.190.10 146 277 3.1E-36 T 29-03-2018 CVS48_RS13585 aa86f94e9e69e922c68404d3e6e70b83 501 SUPERFAMILY SSF53850 19 499 3.87E-102 T 29-03-2018 CVS48_RS03640 0a1e0635b097784823928be638999c46 272 PIRSF PIRSF039085 27 269 1.3E-107 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS03640 0a1e0635b097784823928be638999c46 272 SUPERFAMILY SSF52540 31 264 6.88E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03640 0a1e0635b097784823928be638999c46 272 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS03640 0a1e0635b097784823928be638999c46 272 Pfam PF00005 ABC transporter 46 194 3.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS03640 0a1e0635b097784823928be638999c46 272 SMART SM00382 55 238 4.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03640 0a1e0635b097784823928be638999c46 272 Gene3D G3DSA:3.40.50.300 27 271 6.1E-75 T 29-03-2018 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 466 1.1E-239 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 Gene3D G3DSA:3.40.1060.10 155 288 1.1E-41 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 1.6E-160 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 PRINTS PR00415 Aconitase family signature 108 116 1.8E-49 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 PRINTS PR00415 Aconitase family signature 133 148 1.8E-49 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 PRINTS PR00415 Aconitase family signature 82 95 1.8E-49 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 PRINTS PR00415 Aconitase family signature 209 222 1.8E-49 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 PRINTS PR00415 Aconitase family signature 400 413 1.8E-49 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 PRINTS PR00415 Aconitase family signature 195 208 1.8E-49 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 PRINTS PR00415 Aconitase family signature 119 132 1.8E-49 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 PRINTS PR00415 Aconitase family signature 343 354 1.8E-49 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 PRINTS PR00415 Aconitase family signature 286 300 1.8E-49 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 60.673 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 Gene3D G3DSA:3.30.499.10 1 154 8.2E-42 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 SUPERFAMILY SSF53732 2 466 1.11E-166 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14960 f7f6ff6befd13a7b8b02067eddf99a48 467 Gene3D G3DSA:3.30.499.10 324 467 1.4E-52 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS24320 5a485fd5d7301af12b3ed282cd37baca 147 Gene3D G3DSA:3.40.640.10 11 138 6.1E-4 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS07620 d5fa1f08a9193ac49dfa6c75759a039f 508 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 17 499 3.5E-161 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS07620 d5fa1f08a9193ac49dfa6c75759a039f 508 Gene3D G3DSA:3.90.1300.10 10 508 5.6E-162 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS07620 d5fa1f08a9193ac49dfa6c75759a039f 508 ProSitePatterns PS00571 Amidases signature. 155 186 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CVS48_RS07620 d5fa1f08a9193ac49dfa6c75759a039f 508 SUPERFAMILY SSF75304 12 507 1.26E-149 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS07620 d5fa1f08a9193ac49dfa6c75759a039f 508 Pfam PF01425 Amidase 34 490 8.5E-142 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS07620 d5fa1f08a9193ac49dfa6c75759a039f 508 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 16 501 92.874 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS02005 806ebe790415d2bc408e3b22e33be91e 261 SMART SM00650 20 188 7.1E-80 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CVS48_RS02005 806ebe790415d2bc408e3b22e33be91e 261 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 5 253 6.3E-82 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CVS48_RS02005 806ebe790415d2bc408e3b22e33be91e 261 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 36 63 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CVS48_RS02005 806ebe790415d2bc408e3b22e33be91e 261 Pfam PF00398 Ribosomal RNA adenine dimethylase 4 254 1.1E-57 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CVS48_RS02005 806ebe790415d2bc408e3b22e33be91e 261 Gene3D G3DSA:3.40.50.150 1 198 2.6E-53 T 29-03-2018 CVS48_RS02005 806ebe790415d2bc408e3b22e33be91e 261 Gene3D G3DSA:1.10.8.100 199 258 5.8E-15 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CVS48_RS02005 806ebe790415d2bc408e3b22e33be91e 261 SUPERFAMILY SSF53335 4 256 1.42E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS02005 806ebe790415d2bc408e3b22e33be91e 261 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 4 255 53.534 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CVS48_RS21715 ea4131e1c9300ebdd7f6efedd89ae943 327 Gene3D G3DSA:3.40.190.10 37 296 6.8E-13 T 29-03-2018 CVS48_RS21715 ea4131e1c9300ebdd7f6efedd89ae943 327 PIRSF PIRSF017082 1 327 2.8E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21715 ea4131e1c9300ebdd7f6efedd89ae943 327 SUPERFAMILY SSF53850 114 289 3.62E-11 T 29-03-2018 CVS48_RS21715 ea4131e1c9300ebdd7f6efedd89ae943 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 6.0E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 SMART SM00829 10 342 2.3E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 SUPERFAMILY SSF51735 149 312 1.08E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 Gene3D G3DSA:3.90.180.10 1 192 5.8E-55 T 29-03-2018 CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 145 1.9E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 Gene3D G3DSA:3.40.50.20 272 342 1.4E-5 T 29-03-2018 CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 Gene3D G3DSA:3.40.50.20 193 261 1.6E-16 T 29-03-2018 CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 Pfam PF00107 Zinc-binding dehydrogenase 186 308 7.4E-22 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 SUPERFAMILY SSF50129 9 173 2.2E-51 T 29-03-2018 IPR011032 GroES-like CVS48_RS23210 df51661106b91565c43c53ff8d903c16 354 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 179 207 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CVS48_RS01005 b920eed4b6ba1b067ff9962abd802aa7 495 Gene3D G3DSA:2.70.50.50 24 210 1.3E-36 T 29-03-2018 CVS48_RS01005 b920eed4b6ba1b067ff9962abd802aa7 495 SMART SM00495 439 490 8.2E-8 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CVS48_RS01005 b920eed4b6ba1b067ff9962abd802aa7 495 SUPERFAMILY SSF81296 24 210 4.2E-25 T 29-03-2018 IPR014756 Immunoglobulin E-set CVS48_RS01005 b920eed4b6ba1b067ff9962abd802aa7 495 Gene3D G3DSA:2.10.10.20 429 495 9.6E-10 T 29-03-2018 CVS48_RS01005 b920eed4b6ba1b067ff9962abd802aa7 495 SUPERFAMILY SSF49299 331 417 6.28E-6 T 29-03-2018 IPR000601 PKD domain CVS48_RS01005 b920eed4b6ba1b067ff9962abd802aa7 495 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 24 207 3.1E-25 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CVS48_RS01005 b920eed4b6ba1b067ff9962abd802aa7 495 Gene3D G3DSA:2.60.40.10 327 420 2.2E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS14105 61f941c48fa28cee0e38b55074b2d8a0 181 SUPERFAMILY SSF88946 2 109 1.37E-26 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14105 61f941c48fa28cee0e38b55074b2d8a0 181 Pfam PF04542 Sigma-70 region 2 25 90 1.0E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14105 61f941c48fa28cee0e38b55074b2d8a0 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 180 5.7E-26 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14105 61f941c48fa28cee0e38b55074b2d8a0 181 SUPERFAMILY SSF88659 119 181 5.23E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14105 61f941c48fa28cee0e38b55074b2d8a0 181 Gene3D G3DSA:1.10.10.10 116 181 8.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14105 61f941c48fa28cee0e38b55074b2d8a0 181 Gene3D G3DSA:1.10.1740.10 1 115 6.8E-23 T 29-03-2018 CVS48_RS14105 61f941c48fa28cee0e38b55074b2d8a0 181 Pfam PF08281 Sigma-70, region 4 125 176 1.2E-10 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14755 1c3b7e94e175a3f3f1d1613282a0016f 180 Gene3D G3DSA:3.40.50.2020 9 168 1.1E-23 T 29-03-2018 CVS48_RS14755 1c3b7e94e175a3f3f1d1613282a0016f 180 SUPERFAMILY SSF53271 6 177 1.04E-34 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CVS48_RS14755 1c3b7e94e175a3f3f1d1613282a0016f 180 Pfam PF00156 Phosphoribosyl transferase domain 16 161 4.4E-24 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 137 148 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 15 22 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 SUPERFAMILY SSF52540 7 433 4.67E-174 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 435 208.938 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 10 433 5.0E-174 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 Gene3D G3DSA:3.40.440.10 157 270 1.4E-25 T 29-03-2018 CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 Gene3D G3DSA:3.40.440.10 5 156 2.1E-55 T 29-03-2018 CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 Pfam PF00709 Adenylosuccinate synthetase 9 427 5.9E-174 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 Gene3D G3DSA:3.90.170.10 271 435 1.4E-64 T 29-03-2018 CVS48_RS14750 b3df4f9078f01c0f4da58da9ee1e38c2 435 SMART SM00788 8 428 4.8E-293 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CVS48_RS06205 d90c5c8c5926e241feda30941c6734dd 461 Gene3D G3DSA:3.30.590.10 121 461 3.7E-99 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CVS48_RS06205 d90c5c8c5926e241feda30941c6734dd 461 Gene3D G3DSA:3.10.20.70 15 120 5.3E-11 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS06205 d90c5c8c5926e241feda30941c6734dd 461 SUPERFAMILY SSF55931 121 459 4.41E-102 T 29-03-2018 CVS48_RS06205 d90c5c8c5926e241feda30941c6734dd 461 SMART SM01230 120 376 9.2E-94 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS06205 d90c5c8c5926e241feda30941c6734dd 461 Pfam PF00120 Glutamine synthetase, catalytic domain 121 457 1.9E-94 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS25410 702a9ee3898663d3ddf64262b46e8088 264 SMART SM00382 36 218 7.5E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS25410 702a9ee3898663d3ddf64262b46e8088 264 Pfam PF00005 ABC transporter 28 168 3.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS25410 702a9ee3898663d3ddf64262b46e8088 264 SUPERFAMILY SSF52540 6 235 6.39E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS25410 702a9ee3898663d3ddf64262b46e8088 264 Gene3D G3DSA:3.40.50.300 1 230 5.8E-58 T 29-03-2018 CVS48_RS25410 702a9ee3898663d3ddf64262b46e8088 264 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS17130 fd53f45d7f38552e27418558d4136ccc 238 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 44.302 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CVS48_RS17130 fd53f45d7f38552e27418558d4136ccc 238 Gene3D G3DSA:3.40.1160.10 1 238 3.4E-44 T 29-03-2018 CVS48_RS17130 fd53f45d7f38552e27418558d4136ccc 238 SUPERFAMILY SSF53633 5 237 6.02E-70 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS17130 fd53f45d7f38552e27418558d4136ccc 238 Pfam PF00696 Amino acid kinase family 7 216 2.2E-28 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS17130 fd53f45d7f38552e27418558d4136ccc 238 PIRSF PIRSF005650 1 238 9.1E-92 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CVS48_RS17130 fd53f45d7f38552e27418558d4136ccc 238 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 2.7E-100 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CVS48_RS10930 20c2c65221414f7979469141fd37ce96 373 Pfam PF02661 Fic/DOC family 118 230 1.7E-14 T 29-03-2018 IPR003812 Fido domain CVS48_RS10930 20c2c65221414f7979469141fd37ce96 373 Pfam PF13776 Domain of unknown function (DUF4172) 8 89 6.9E-31 T 29-03-2018 IPR025230 Domain of unknown function DUF4172 CVS48_RS10930 20c2c65221414f7979469141fd37ce96 373 Gene3D G3DSA:1.10.3290.10 26 286 1.9E-44 T 29-03-2018 IPR003812 Fido domain CVS48_RS10930 20c2c65221414f7979469141fd37ce96 373 SUPERFAMILY SSF140931 100 300 7.46E-34 T 29-03-2018 IPR003812 Fido domain CVS48_RS10930 20c2c65221414f7979469141fd37ce96 373 Gene3D G3DSA:1.10.10.10 287 373 1.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18810 19586185475b3e151e927dd9d9171d15 314 SMART SM00559 54 182 5.0E-27 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CVS48_RS18810 19586185475b3e151e927dd9d9171d15 314 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 3 263 30.611 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CVS48_RS18810 19586185475b3e151e927dd9d9171d15 314 Gene3D G3DSA:2.40.290.10 3 182 3.4E-29 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain CVS48_RS18810 19586185475b3e151e927dd9d9171d15 314 TIGRFAM TIGR02772 Ku_bact: Ku protein 4 264 4.9E-92 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CVS48_RS18810 19586185475b3e151e927dd9d9171d15 314 Pfam PF02735 Ku70/Ku80 beta-barrel domain 13 190 1.3E-32 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CVS48_RS18810 19586185475b3e151e927dd9d9171d15 314 PIRSF PIRSF006493 1 302 1.3E-93 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CVS48_RS18810 19586185475b3e151e927dd9d9171d15 314 SUPERFAMILY SSF100939 4 263 1.88E-48 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 176 191 1.8E-35 T 29-03-2018 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 1.8E-35 T 29-03-2018 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 28 50 1.8E-35 T 29-03-2018 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 1.8E-35 T 29-03-2018 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 352 1.8E-35 T 29-03-2018 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 Pfam PF01494 FAD binding domain 28 363 4.5E-67 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 Gene3D G3DSA:3.50.50.60 4 183 4.3E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 Gene3D G3DSA:3.40.30.20 409 484 0.2 T 29-03-2018 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 Gene3D G3DSA:3.40.30.20 486 555 3.9E-5 T 29-03-2018 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 Gene3D G3DSA:3.30.9.10 184 308 6.1E-27 T 29-03-2018 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 Gene3D G3DSA:3.30.9.10 309 400 2.4E-16 T 29-03-2018 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 SUPERFAMILY SSF51905 288 400 1.7E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10815 5537d7c8e170dba09b26ee7c26918222 559 SUPERFAMILY SSF51905 28 197 1.7E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS07390 6ab8abe1b3126a253632a622b3a1c6e3 218 Pfam PF00694 Aconitase C-terminal domain 6 120 8.8E-30 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS07390 6ab8abe1b3126a253632a622b3a1c6e3 218 SUPERFAMILY SSF52016 3 178 4.51E-47 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS07390 6ab8abe1b3126a253632a622b3a1c6e3 218 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 6 183 7.5E-52 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CVS48_RS07390 6ab8abe1b3126a253632a622b3a1c6e3 218 Gene3D G3DSA:3.20.19.10 3 176 1.1E-35 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS13410 0b8d572d2f6f203f8377fa7a96d0fb5f 293 ProSitePatterns PS01058 SAICAR synthetase signature 2. 205 213 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS13410 0b8d572d2f6f203f8377fa7a96d0fb5f 293 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 293 25.343 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS13410 0b8d572d2f6f203f8377fa7a96d0fb5f 293 Pfam PF01259 SAICAR synthetase 16 268 1.0E-102 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS13410 0b8d572d2f6f203f8377fa7a96d0fb5f 293 Gene3D G3DSA:3.30.200.20 6 111 1.1E-31 T 29-03-2018 CVS48_RS13410 0b8d572d2f6f203f8377fa7a96d0fb5f 293 SUPERFAMILY SSF56104 6 291 5.89E-102 T 29-03-2018 CVS48_RS13410 0b8d572d2f6f203f8377fa7a96d0fb5f 293 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 291 1.9E-81 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CVS48_RS13410 0b8d572d2f6f203f8377fa7a96d0fb5f 293 Gene3D G3DSA:3.30.470.20 112 249 5.8E-53 T 29-03-2018 CVS48_RS13410 0b8d572d2f6f203f8377fa7a96d0fb5f 293 ProSitePatterns PS01057 SAICAR synthetase signature 1. 106 120 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 168 6.0E-24 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 Gene3D G3DSA:3.30.300.20 195 296 4.8E-38 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 278 2.0E-78 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 SUPERFAMILY SSF52540 11 202 6.21E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 79 97 6.5E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 6.5E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 Gene3D G3DSA:1.20.120.430 2 62 3.6E-18 T 29-03-2018 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 Gene3D G3DSA:3.40.50.300 63 194 1.0E-14 T 29-03-2018 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 SUPERFAMILY SSF54814 181 296 1.5E-36 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 Pfam PF01926 50S ribosome-binding GTPase 11 122 1.2E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 Hamap MF_00367 GTPase Era [era]. 6 295 33.944 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS28260 9bce23dfeb880b2e1ed554da553ecbda 296 Pfam PF07650 KH domain 208 283 6.1E-16 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS15895 c4bb11bc07032d1112c54d889eac565c 640 SUPERFAMILY SSF90123 24 328 9.68E-44 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS15895 c4bb11bc07032d1112c54d889eac565c 640 Pfam PF00664 ABC transporter transmembrane region 32 306 5.9E-17 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS15895 c4bb11bc07032d1112c54d889eac565c 640 Pfam PF00005 ABC transporter 372 520 3.6E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS15895 c4bb11bc07032d1112c54d889eac565c 640 Gene3D G3DSA:1.20.1560.10 1 335 6.0E-32 T 29-03-2018 CVS48_RS15895 c4bb11bc07032d1112c54d889eac565c 640 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS15895 c4bb11bc07032d1112c54d889eac565c 640 Gene3D G3DSA:3.40.50.300 341 596 6.7E-77 T 29-03-2018 CVS48_RS15895 c4bb11bc07032d1112c54d889eac565c 640 SUPERFAMILY SSF52540 345 591 9.54E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS15895 c4bb11bc07032d1112c54d889eac565c 640 SMART SM00382 380 566 2.3E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03485 00bf9c9c28ce83f73cf4fe4d2b6624d9 164 SMART SM00347 39 140 3.7E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS03485 00bf9c9c28ce83f73cf4fe4d2b6624d9 164 SUPERFAMILY SSF46785 13 150 4.52E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03485 00bf9c9c28ce83f73cf4fe4d2b6624d9 164 Pfam PF01047 MarR family 47 104 7.3E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS03485 00bf9c9c28ce83f73cf4fe4d2b6624d9 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 6.6E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS03485 00bf9c9c28ce83f73cf4fe4d2b6624d9 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 6.6E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS03485 00bf9c9c28ce83f73cf4fe4d2b6624d9 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 6.6E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS03485 00bf9c9c28ce83f73cf4fe4d2b6624d9 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CVS48_RS03485 00bf9c9c28ce83f73cf4fe4d2b6624d9 164 Gene3D G3DSA:1.10.10.10 2 156 7.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28605 7a954ed701825beaeba91cfad5338be0 712 Pfam PF14247 Putative metallopeptidase 272 414 3.0E-28 T 29-03-2018 IPR025644 Putative metallopeptidase CVS48_RS28605 7a954ed701825beaeba91cfad5338be0 712 Pfam PF14247 Putative metallopeptidase 459 513 3.9E-11 T 29-03-2018 IPR025644 Putative metallopeptidase CVS48_RS28605 7a954ed701825beaeba91cfad5338be0 712 SUPERFAMILY SSF52821 592 705 1.23E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS28605 7a954ed701825beaeba91cfad5338be0 712 Gene3D G3DSA:3.40.250.10 585 712 4.6E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS08845 cab5f74a548267b95540f0ecb85be205 267 Gene3D G3DSA:1.10.3720.10 5 263 1.1E-40 T 29-03-2018 CVS48_RS08845 cab5f74a548267b95540f0ecb85be205 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 260 5.3E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS08845 cab5f74a548267b95540f0ecb85be205 267 SUPERFAMILY SSF161098 4 257 6.17E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20050 5d41b7e84941ea58b1edf41827b0ff0c 226 Pfam PF01965 DJ-1/PfpI family 25 222 1.3E-15 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS20050 5d41b7e84941ea58b1edf41827b0ff0c 226 SUPERFAMILY SSF52317 1 224 3.93E-77 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS20050 5d41b7e84941ea58b1edf41827b0ff0c 226 Gene3D G3DSA:3.40.50.880 1 226 5.2E-62 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS27345 ebf7ef7e08822a5ba756e48350b6e29c 243 Gene3D G3DSA:3.90.79.10 47 238 3.6E-42 T 29-03-2018 CVS48_RS27345 ebf7ef7e08822a5ba756e48350b6e29c 243 SUPERFAMILY SSF55811 69 229 6.16E-36 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS27345 ebf7ef7e08822a5ba756e48350b6e29c 243 Pfam PF00293 NUDIX domain 78 159 6.6E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CVS48_RS09265 c11ece59a7cb1b37cd3946286fffccf9 377 Pfam PF13518 Helix-turn-helix domain 12 62 6.5E-12 T 29-03-2018 CVS48_RS09265 c11ece59a7cb1b37cd3946286fffccf9 377 Gene3D G3DSA:3.30.420.10 126 328 5.1E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS09265 c11ece59a7cb1b37cd3946286fffccf9 377 SUPERFAMILY SSF46689 11 115 2.15E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS09265 c11ece59a7cb1b37cd3946286fffccf9 377 Gene3D G3DSA:1.10.10.10 10 65 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09265 c11ece59a7cb1b37cd3946286fffccf9 377 Pfam PF00665 Integrase core domain 134 257 2.2E-25 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS09265 c11ece59a7cb1b37cd3946286fffccf9 377 SUPERFAMILY SSF53098 130 302 3.67E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS03715 c11ece59a7cb1b37cd3946286fffccf9 377 Pfam PF13518 Helix-turn-helix domain 12 62 6.5E-12 T 29-03-2018 CVS48_RS03715 c11ece59a7cb1b37cd3946286fffccf9 377 Gene3D G3DSA:3.30.420.10 126 328 5.1E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS03715 c11ece59a7cb1b37cd3946286fffccf9 377 SUPERFAMILY SSF46689 11 115 2.15E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS03715 c11ece59a7cb1b37cd3946286fffccf9 377 Gene3D G3DSA:1.10.10.10 10 65 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03715 c11ece59a7cb1b37cd3946286fffccf9 377 Pfam PF00665 Integrase core domain 134 257 2.2E-25 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS03715 c11ece59a7cb1b37cd3946286fffccf9 377 SUPERFAMILY SSF53098 130 302 3.67E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS20230 bee3832745a35ae26f188ff3be726b13 244 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS20230 bee3832745a35ae26f188ff3be726b13 244 SMART SM00382 26 221 2.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS20230 bee3832745a35ae26f188ff3be726b13 244 Gene3D G3DSA:3.40.50.300 1 240 4.8E-76 T 29-03-2018 CVS48_RS20230 bee3832745a35ae26f188ff3be726b13 244 PIRSF PIRSF039085 1 241 3.8E-108 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS20230 bee3832745a35ae26f188ff3be726b13 244 Pfam PF00005 ABC transporter 17 165 6.4E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS20230 bee3832745a35ae26f188ff3be726b13 244 SUPERFAMILY SSF52540 1 235 2.92E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS25835 60baa7ec49a85b56443c6713421a8aaf 201 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 12 201 8.9E-65 T 29-03-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CVS48_RS25835 60baa7ec49a85b56443c6713421a8aaf 201 SUPERFAMILY SSF49482 9 200 7.33E-46 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CVS48_RS25835 60baa7ec49a85b56443c6713421a8aaf 201 Pfam PF00775 Dioxygenase 45 124 5.1E-10 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CVS48_RS25835 60baa7ec49a85b56443c6713421a8aaf 201 Gene3D G3DSA:2.60.130.10 2 201 8.5E-45 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 SUPERFAMILY SSF51905 44 263 4.53E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 44 264 4.2E-17 T 29-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 245 1.5E-6 T 29-03-2018 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 47 66 1.5E-6 T 29-03-2018 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 1.5E-6 T 29-03-2018 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 Gene3D G3DSA:3.50.50.60 41 220 1.2E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 SUPERFAMILY SSF51905 211 378 1.4E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 Gene3D G3DSA:3.50.50.60 221 490 4.3E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 46 68 2.8E-10 T 29-03-2018 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 227 252 2.8E-10 T 29-03-2018 CVS48_RS21010 cc7f3e18cbe1a64d3c1f0bd257641faa 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 185 194 2.8E-10 T 29-03-2018 CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 Gene3D G3DSA:1.10.10.60 226 254 1.1E-7 T 29-03-2018 CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 Pfam PF12833 Helix-turn-helix domain 238 318 1.7E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 300 316 1.5E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 285 300 1.5E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 SUPERFAMILY SSF46689 267 318 1.34E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 SMART SM00342 231 316 4.4E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 SUPERFAMILY SSF51215 78 137 1.2E-5 T 29-03-2018 CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 Pfam PF14525 AraC-binding-like domain 20 196 6.8E-22 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 Gene3D G3DSA:1.10.10.60 265 319 1.7E-15 T 29-03-2018 CVS48_RS06475 87dd7baa52a10d0df056d8114832f98b 319 Gene3D G3DSA:2.60.120.10 8 225 5.8E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS05675 085884d750e24b696ef25e9050628b20 260 Gene3D G3DSA:3.40.190.10 144 254 1.8E-11 T 29-03-2018 CVS48_RS05675 085884d750e24b696ef25e9050628b20 260 SMART SM00062 35 255 1.6E-41 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS05675 085884d750e24b696ef25e9050628b20 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 253 3.8E-50 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS05675 085884d750e24b696ef25e9050628b20 260 Gene3D G3DSA:3.40.190.10 7 143 1.8E-29 T 29-03-2018 CVS48_RS05675 085884d750e24b696ef25e9050628b20 260 SUPERFAMILY SSF53850 7 254 9.32E-55 T 29-03-2018 CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 SUPERFAMILY SSF53850 93 300 1.02E-30 T 29-03-2018 CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 SUPERFAMILY SSF46785 5 82 1.03E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 Gene3D G3DSA:3.40.190.10 92 178 1.5E-8 T 29-03-2018 CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.0E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 Pfam PF03466 LysR substrate binding domain 93 298 2.1E-29 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 Gene3D G3DSA:1.10.10.10 6 83 7.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13560 d9ba275ee16c6a5fe9f428fac344b53d 304 Gene3D G3DSA:3.40.190.10 179 267 2.3E-19 T 29-03-2018 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 Gene3D G3DSA:3.50.50.60 2 381 3.5E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 SUPERFAMILY SSF51905 256 364 6.48E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 SUPERFAMILY SSF51905 5 172 6.48E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 Gene3D G3DSA:3.40.30.20 464 523 0.0013 T 29-03-2018 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 300 8.9E-42 T 29-03-2018 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 8.9E-42 T 29-03-2018 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 8.9E-42 T 29-03-2018 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 8.9E-42 T 29-03-2018 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 320 8.9E-42 T 29-03-2018 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 8.9E-42 T 29-03-2018 CVS48_RS11910 0dea1ac2eef1abc1c084f89e6aea355a 525 Pfam PF01494 FAD binding domain 4 332 2.3E-71 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 Gene3D G3DSA:3.40.50.720 1 41 7.4E-9 T 29-03-2018 CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 Gene3D G3DSA:3.40.50.720 42 260 4.5E-61 T 29-03-2018 CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 SUPERFAMILY SSF51735 3 259 1.32E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 259 7.7E-106 T 29-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 4.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS00095 d298dff7e1dfc097ff8b14a60e0bfc66 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 258 3.7E-58 T 29-03-2018 CVS48_RS23225 1df278c8fc4b8fc6a9dd38101bd6b3c9 384 SUPERFAMILY SSF53187 299 383 1.89E-83 T 29-03-2018 CVS48_RS23225 1df278c8fc4b8fc6a9dd38101bd6b3c9 384 SUPERFAMILY SSF53187 2 198 1.89E-83 T 29-03-2018 CVS48_RS23225 1df278c8fc4b8fc6a9dd38101bd6b3c9 384 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 371 2.2E-105 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS23225 1df278c8fc4b8fc6a9dd38101bd6b3c9 384 Pfam PF01546 Peptidase family M20/M25/M40 74 380 7.8E-35 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS23225 1df278c8fc4b8fc6a9dd38101bd6b3c9 384 SUPERFAMILY SSF55031 184 295 1.44E-28 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS23225 1df278c8fc4b8fc6a9dd38101bd6b3c9 384 PIRSF PIRSF005962 7 384 5.6E-121 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS23225 1df278c8fc4b8fc6a9dd38101bd6b3c9 384 Gene3D G3DSA:3.40.630.10 267 384 1.6E-23 T 29-03-2018 CVS48_RS23225 1df278c8fc4b8fc6a9dd38101bd6b3c9 384 Gene3D G3DSA:3.40.630.10 1 266 1.5E-64 T 29-03-2018 CVS48_RS23225 1df278c8fc4b8fc6a9dd38101bd6b3c9 384 Pfam PF07687 Peptidase dimerisation domain 186 280 6.9E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS02505 0a1cc1cbc50aaab75edb84d0a071f244 365 SUPERFAMILY SSF81799 135 234 5.36E-33 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS02505 0a1cc1cbc50aaab75edb84d0a071f244 365 Pfam PF01795 MraW methylase family 2 328 5.9E-100 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS02505 0a1cc1cbc50aaab75edb84d0a071f244 365 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 43 328 1.3E-97 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS02505 0a1cc1cbc50aaab75edb84d0a071f244 365 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 329 36.135 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS02505 0a1cc1cbc50aaab75edb84d0a071f244 365 SUPERFAMILY SSF53335 234 328 3.97E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS02505 0a1cc1cbc50aaab75edb84d0a071f244 365 SUPERFAMILY SSF53335 5 134 3.97E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS02505 0a1cc1cbc50aaab75edb84d0a071f244 365 PIRSF PIRSF004486 1 330 1.2E-94 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS02505 0a1cc1cbc50aaab75edb84d0a071f244 365 Gene3D G3DSA:1.10.150.170 143 236 4.7E-35 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS02505 0a1cc1cbc50aaab75edb84d0a071f244 365 Gene3D G3DSA:3.40.50.150 5 142 5.7E-13 T 29-03-2018 CVS48_RS01850 36f6ce035fb80bca4a2d6dc5a82e2ec1 277 Gene3D G3DSA:3.20.20.360 2 253 5.6E-52 T 29-03-2018 CVS48_RS01850 36f6ce035fb80bca4a2d6dc5a82e2ec1 277 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 7 214 5.3E-36 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CVS48_RS01850 36f6ce035fb80bca4a2d6dc5a82e2ec1 277 PIRSF PIRSF015582 1 275 1.6E-81 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like CVS48_RS01850 36f6ce035fb80bca4a2d6dc5a82e2ec1 277 SUPERFAMILY SSF51621 4 226 3.49E-63 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS01340 a58d6e60d1628570c6dd0b3da8f1dd7a 72 Gene3D G3DSA:2.60.260.40 9 63 2.9E-18 T 29-03-2018 CVS48_RS01340 a58d6e60d1628570c6dd0b3da8f1dd7a 72 Pfam PF10276 Zinc-finger domain 25 60 1.0E-9 T 29-03-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 Hamap MF_00900 GTPase HflX [hflX]. 19 355 44.645 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 SUPERFAMILY SSF52540 190 350 4.13E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 Pfam PF16360 GTP-binding GTPase Middle Region 106 184 9.7E-29 T 29-03-2018 IPR032305 GTP-binding protein, middle domain CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 Pfam PF13167 GTP-binding GTPase N-terminal 18 104 8.7E-29 T 29-03-2018 IPR025121 GTPase HflX, N-terminal CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 259 277 5.9E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 213 231 5.9E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 192 212 5.9E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 Gene3D G3DSA:3.40.50.300 162 223 1.4E-11 T 29-03-2018 CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 2 350 5.4E-147 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 Gene3D G3DSA:3.40.50.300 224 345 1.4E-14 T 29-03-2018 CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 Pfam PF01926 50S ribosome-binding GTPase 192 310 4.0E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS14730 9ec8df873c5e1fe4a8ec9b65aef058ac 368 PIRSF PIRSF006809 1 362 1.3E-135 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 SUPERFAMILY SSF52540 303 527 5.33E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 Gene3D G3DSA:3.40.50.300 285 537 2.9E-43 T 29-03-2018 CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 SUPERFAMILY SSF52540 123 255 6.59E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 SUPERFAMILY SSF52540 2 92 6.59E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 SMART SM00382 351 518 1.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 SMART SM00382 26 228 1.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 Pfam PF00005 ABC transporter 17 182 8.5E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 Pfam PF00005 ABC transporter 343 473 1.9E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 Pfam PF12848 ABC transporter 221 303 2.2E-24 T 29-03-2018 IPR032781 ABC-transporter extension domain CVS48_RS19160 9c6b205d5bd35c7c3207ecc2290f0233 543 Gene3D G3DSA:3.40.50.300 1 284 1.8E-48 T 29-03-2018 CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 16 474 2.2E-141 T 29-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 474 4.8E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 SMART SM00388 256 322 2.1E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 456 2.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 2.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 2.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 Gene3D G3DSA:3.30.565.10 326 478 3.9E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 SUPERFAMILY SSF55874 312 475 1.31E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 SMART SM00387 366 477 2.6E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 SUPERFAMILY SSF47384 239 322 8.04E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 Gene3D G3DSA:1.10.287.130 246 318 1.9E-10 T 29-03-2018 CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 SMART SM00304 202 255 6.1E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS00535 90462af94f8c3e338acc65bfba14f5d3 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 257 320 2.3E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS09950 90f83d48b142e37b40214f2dabb185ae 293 SUPERFAMILY SSF103481 45 136 1.31E-16 T 29-03-2018 CVS48_RS09950 90f83d48b142e37b40214f2dabb185ae 293 Pfam PF00892 EamA-like transporter family 150 283 6.0E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS09950 90f83d48b142e37b40214f2dabb185ae 293 Pfam PF00892 EamA-like transporter family 9 135 1.3E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS09950 90f83d48b142e37b40214f2dabb185ae 293 SUPERFAMILY SSF103481 189 288 7.32E-14 T 29-03-2018 CVS48_RS11500 5954795855c75398afb095d911e27e04 279 Gene3D G3DSA:1.10.10.60 174 229 1.8E-6 T 29-03-2018 CVS48_RS11500 5954795855c75398afb095d911e27e04 279 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 226 268 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS11500 5954795855c75398afb095d911e27e04 279 SMART SM00342 189 272 1.9E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS11500 5954795855c75398afb095d911e27e04 279 SUPERFAMILY SSF52172 14 142 4.7E-36 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS11500 5954795855c75398afb095d911e27e04 279 Gene3D G3DSA:1.10.10.60 230 278 1.1E-13 T 29-03-2018 CVS48_RS11500 5954795855c75398afb095d911e27e04 279 Pfam PF12833 Helix-turn-helix domain 195 273 2.0E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS11500 5954795855c75398afb095d911e27e04 279 SUPERFAMILY SSF46689 226 274 2.02E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS11500 5954795855c75398afb095d911e27e04 279 Gene3D G3DSA:3.40.50.2300 12 144 6.1E-33 T 29-03-2018 CVS48_RS11500 5954795855c75398afb095d911e27e04 279 Pfam PF00072 Response regulator receiver domain 21 131 5.5E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS11500 5954795855c75398afb095d911e27e04 279 SMART SM00448 19 132 1.8E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS09145 dc34b1261d6335eb45a11a5c1bb55607 308 Gene3D G3DSA:3.40.190.10 183 272 3.8E-18 T 29-03-2018 CVS48_RS09145 dc34b1261d6335eb45a11a5c1bb55607 308 SUPERFAMILY SSF53850 87 297 1.49E-32 T 29-03-2018 CVS48_RS09145 dc34b1261d6335eb45a11a5c1bb55607 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.8E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09145 dc34b1261d6335eb45a11a5c1bb55607 308 SUPERFAMILY SSF46785 6 90 4.27E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09145 dc34b1261d6335eb45a11a5c1bb55607 308 Gene3D G3DSA:1.10.10.10 1 91 3.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09145 dc34b1261d6335eb45a11a5c1bb55607 308 Gene3D G3DSA:3.40.190.10 93 182 8.1E-15 T 29-03-2018 CVS48_RS09145 dc34b1261d6335eb45a11a5c1bb55607 308 Pfam PF03466 LysR substrate binding domain 92 297 2.7E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS25220 66b6817b5d165d5296b1d06c929729ac 326 SUPERFAMILY SSF53850 107 286 9.42E-18 T 29-03-2018 CVS48_RS25220 66b6817b5d165d5296b1d06c929729ac 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 5.8E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25220 66b6817b5d165d5296b1d06c929729ac 326 Gene3D G3DSA:3.40.190.10 34 297 7.3E-13 T 29-03-2018 CVS48_RS25220 66b6817b5d165d5296b1d06c929729ac 326 PIRSF PIRSF017082 1 323 5.0E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01795 5790570bb91ff6e22a5a3d5714b661f0 179 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 12 149 1.0E-36 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CVS48_RS01795 5790570bb91ff6e22a5a3d5714b661f0 179 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 13 140 6.3E-34 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CVS48_RS01795 5790570bb91ff6e22a5a3d5714b661f0 179 SUPERFAMILY SSF52540 36 148 1.08E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01795 5790570bb91ff6e22a5a3d5714b661f0 179 Gene3D G3DSA:3.40.50.300 5 163 2.1E-46 T 29-03-2018 CVS48_RS22855 f30083b529284c32a5281f53fab8a8c6 60 Pfam PF09791 Oxidoreductase-like protein, N-terminal 14 52 2.0E-14 T 29-03-2018 IPR019180 Oxidoreductase-like, N-terminal CVS48_RS21865 fea7813b06a52cc9483eeaacdbef1522 273 SMART SM00382 34 235 6.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21865 fea7813b06a52cc9483eeaacdbef1522 273 Pfam PF00005 ABC transporter 26 187 1.6E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS21865 fea7813b06a52cc9483eeaacdbef1522 273 Gene3D G3DSA:3.40.50.300 1 263 3.3E-58 T 29-03-2018 CVS48_RS21865 fea7813b06a52cc9483eeaacdbef1522 273 SUPERFAMILY SSF52540 8 258 2.09E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21865 fea7813b06a52cc9483eeaacdbef1522 273 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 2.0E-12 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS09780 caf23f4665216e8de111367f8cca886d 265 Gene3D G3DSA:3.30.450.40 87 265 4.1E-36 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09780 caf23f4665216e8de111367f8cca886d 265 SMART SM00346 15 105 4.1E-17 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS09780 caf23f4665216e8de111367f8cca886d 265 Gene3D G3DSA:1.10.10.10 7 76 8.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09780 caf23f4665216e8de111367f8cca886d 265 Pfam PF01614 Bacterial transcriptional regulator 138 248 8.3E-9 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS09780 caf23f4665216e8de111367f8cca886d 265 SUPERFAMILY SSF55781 73 259 1.05E-35 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09780 caf23f4665216e8de111367f8cca886d 265 Pfam PF09339 IclR helix-turn-helix domain 18 67 1.8E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS09780 caf23f4665216e8de111367f8cca886d 265 SUPERFAMILY SSF46785 17 87 7.04E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07820 854f99635c4159f5b5f9b855f9124221 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS07820 854f99635c4159f5b5f9b855f9124221 296 SUPERFAMILY SSF46785 3 113 9.98E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07820 854f99635c4159f5b5f9b855f9124221 296 Pfam PF03466 LysR substrate binding domain 90 293 1.7E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS07820 854f99635c4159f5b5f9b855f9124221 296 SUPERFAMILY SSF53850 90 295 4.5E-38 T 29-03-2018 CVS48_RS07820 854f99635c4159f5b5f9b855f9124221 296 Gene3D G3DSA:3.40.190.10 90 178 1.5E-12 T 29-03-2018 CVS48_RS07820 854f99635c4159f5b5f9b855f9124221 296 Gene3D G3DSA:3.40.190.10 179 265 3.7E-19 T 29-03-2018 CVS48_RS07820 854f99635c4159f5b5f9b855f9124221 296 Gene3D G3DSA:1.10.10.10 1 85 3.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02585 2a621345c8ea17bb289c2615797b98b3 561 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 557 2.6E-226 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS02585 2a621345c8ea17bb289c2615797b98b3 561 SUPERFAMILY SSF52016 380 558 3.61E-57 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS02585 2a621345c8ea17bb289c2615797b98b3 561 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS02585 2a621345c8ea17bb289c2615797b98b3 561 Pfam PF00920 Dehydratase family 36 554 1.1E-202 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS02585 2a621345c8ea17bb289c2615797b98b3 561 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 5 557 43.957 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS02585 2a621345c8ea17bb289c2615797b98b3 561 SUPERFAMILY SSF143975 4 378 9.81E-132 T 29-03-2018 CVS48_RS02585 2a621345c8ea17bb289c2615797b98b3 561 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS21990 f3c755850c44679ef4e9bd2f13eca385 68 PIRSF PIRSF002599 1 68 2.5E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CVS48_RS21990 f3c755850c44679ef4e9bd2f13eca385 68 Gene3D G3DSA:2.40.50.140 1 67 1.3E-26 T 29-03-2018 CVS48_RS21990 f3c755850c44679ef4e9bd2f13eca385 68 SMART SM00357 3 67 7.9E-28 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CVS48_RS21990 f3c755850c44679ef4e9bd2f13eca385 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.6E-29 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS21990 f3c755850c44679ef4e9bd2f13eca385 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CVS48_RS21990 f3c755850c44679ef4e9bd2f13eca385 68 SUPERFAMILY SSF50249 1 66 1.37E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS21990 f3c755850c44679ef4e9bd2f13eca385 68 PRINTS PR00050 Cold shock protein signature 25 34 8.0E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS21990 f3c755850c44679ef4e9bd2f13eca385 68 PRINTS PR00050 Cold shock protein signature 40 58 8.0E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS21990 f3c755850c44679ef4e9bd2f13eca385 68 PRINTS PR00050 Cold shock protein signature 4 19 8.0E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS15180 8014bd3117ae746b43a2f23cc3be826e 340 SUPERFAMILY SSF55681 93 339 3.42E-75 T 29-03-2018 CVS48_RS15180 8014bd3117ae746b43a2f23cc3be826e 340 Pfam PF01409 tRNA synthetases class II core domain (F) 93 338 1.4E-92 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CVS48_RS15180 8014bd3117ae746b43a2f23cc3be826e 340 Gene3D G3DSA:3.30.930.10 8 340 4.6E-86 T 29-03-2018 CVS48_RS15180 8014bd3117ae746b43a2f23cc3be826e 340 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 338 45.85 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CVS48_RS15180 8014bd3117ae746b43a2f23cc3be826e 340 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 5.4E-22 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CVS48_RS15180 8014bd3117ae746b43a2f23cc3be826e 340 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 339 4.7E-97 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CVS48_RS15180 8014bd3117ae746b43a2f23cc3be826e 340 SUPERFAMILY SSF46589 16 100 1.2E-20 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CVS48_RS24040 032713d75c07e990d88ed372cdd99520 358 SUPERFAMILY SSF52402 42 265 1.64E-50 T 29-03-2018 CVS48_RS24040 032713d75c07e990d88ed372cdd99520 358 Pfam PF01171 PP-loop family 49 232 3.5E-47 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CVS48_RS24040 032713d75c07e990d88ed372cdd99520 358 Gene3D G3DSA:3.40.50.620 44 260 5.3E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS24040 032713d75c07e990d88ed372cdd99520 358 SUPERFAMILY SSF82829 278 356 2.62E-18 T 29-03-2018 CVS48_RS24040 032713d75c07e990d88ed372cdd99520 358 Pfam PF09179 TilS substrate binding domain 284 353 3.2E-15 T 29-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CVS48_RS24040 032713d75c07e990d88ed372cdd99520 358 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 49 235 1.3E-43 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CVS48_RS24040 032713d75c07e990d88ed372cdd99520 358 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 35 345 21.427 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CVS48_RS22910 8cc3112cfc00a70c0680c5df8cc9afdf 267 Gene3D G3DSA:3.40.50.720 1 132 1.7E-21 T 29-03-2018 CVS48_RS22910 8cc3112cfc00a70c0680c5df8cc9afdf 267 SUPERFAMILY SSF55347 121 236 1.24E-26 T 29-03-2018 CVS48_RS22910 8cc3112cfc00a70c0680c5df8cc9afdf 267 PIRSF PIRSF005227 1 267 1.6E-81 T 29-03-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CVS48_RS22910 8cc3112cfc00a70c0680c5df8cc9afdf 267 Gene3D G3DSA:3.30.360.10 133 236 5.6E-37 T 29-03-2018 CVS48_RS22910 8cc3112cfc00a70c0680c5df8cc9afdf 267 Pfam PF01958 Domain of unknown function DUF108 166 253 1.9E-29 T 29-03-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 CVS48_RS22910 8cc3112cfc00a70c0680c5df8cc9afdf 267 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 118 2.2E-17 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CVS48_RS22910 8cc3112cfc00a70c0680c5df8cc9afdf 267 SUPERFAMILY SSF51735 4 150 2.45E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS22910 8cc3112cfc00a70c0680c5df8cc9afdf 267 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 3 265 32.157 T 29-03-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CVS48_RS16145 ff33e9227d1de846c0e90b83a9e18966 475 SUPERFAMILY SSF52540 91 472 7.28E-102 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16145 ff33e9227d1de846c0e90b83a9e18966 475 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 5 472 7.7E-215 T 29-03-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 CVS48_RS16145 ff33e9227d1de846c0e90b83a9e18966 475 Pfam PF00437 Type II/IV secretion system protein 117 379 3.8E-86 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS16145 ff33e9227d1de846c0e90b83a9e18966 475 Gene3D G3DSA:3.40.50.300 213 475 2.3E-65 T 29-03-2018 CVS48_RS16145 ff33e9227d1de846c0e90b83a9e18966 475 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 307 321 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS16145 ff33e9227d1de846c0e90b83a9e18966 475 SUPERFAMILY SSF160246 4 66 9.94E-9 T 29-03-2018 CVS48_RS16145 ff33e9227d1de846c0e90b83a9e18966 475 Gene3D G3DSA:3.30.450.90 75 212 2.4E-47 T 29-03-2018 CVS48_RS16145 ff33e9227d1de846c0e90b83a9e18966 475 SMART SM00382 240 363 7.9E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21090 b72ecd304c91f7595c8e5c02dcdae86d 262 Gene3D G3DSA:3.30.450.40 79 260 5.4E-32 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS21090 b72ecd304c91f7595c8e5c02dcdae86d 262 SUPERFAMILY SSF46785 13 86 8.38E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21090 b72ecd304c91f7595c8e5c02dcdae86d 262 Pfam PF09339 IclR helix-turn-helix domain 14 65 1.5E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS21090 b72ecd304c91f7595c8e5c02dcdae86d 262 SMART SM00346 12 103 1.3E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS21090 b72ecd304c91f7595c8e5c02dcdae86d 262 Pfam PF01614 Bacterial transcriptional regulator 135 251 4.6E-7 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS21090 b72ecd304c91f7595c8e5c02dcdae86d 262 Gene3D G3DSA:1.10.10.10 1 73 6.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21090 b72ecd304c91f7595c8e5c02dcdae86d 262 SUPERFAMILY SSF55781 80 257 3.53E-32 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS04635 0c13eb9f65d5a0a44d54d1dc0000f80b 749 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 11 746 4.3E-294 T 29-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CVS48_RS04635 0c13eb9f65d5a0a44d54d1dc0000f80b 749 Pfam PF01568 Molydopterin dinucleotide binding domain 635 741 4.5E-12 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CVS48_RS04635 0c13eb9f65d5a0a44d54d1dc0000f80b 749 PIRSF PIRSF000144 2 749 0.0 T 29-03-2018 CVS48_RS04635 0c13eb9f65d5a0a44d54d1dc0000f80b 749 SUPERFAMILY SSF50692 633 748 1.13E-17 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CVS48_RS04635 0c13eb9f65d5a0a44d54d1dc0000f80b 749 SUPERFAMILY SSF53706 46 623 4.19E-149 T 29-03-2018 CVS48_RS04635 0c13eb9f65d5a0a44d54d1dc0000f80b 749 Pfam PF00384 Molybdopterin oxidoreductase 107 487 4.3E-23 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS04635 0c13eb9f65d5a0a44d54d1dc0000f80b 749 Gene3D G3DSA:3.40.50.740 108 269 3.2E-34 T 29-03-2018 CVS48_RS04635 0c13eb9f65d5a0a44d54d1dc0000f80b 749 Gene3D G3DSA:2.40.40.20 602 748 1.6E-21 T 29-03-2018 CVS48_RS04635 0c13eb9f65d5a0a44d54d1dc0000f80b 749 Gene3D G3DSA:3.40.50.740 320 601 1.8E-45 T 29-03-2018 CVS48_RS24060 5f8c382533057ab3a5c947e5ec759052 227 Pfam PF14559 Tetratricopeptide repeat 125 186 1.6E-6 T 29-03-2018 CVS48_RS24060 5f8c382533057ab3a5c947e5ec759052 227 SUPERFAMILY SSF48452 85 193 2.2E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS24060 5f8c382533057ab3a5c947e5ec759052 227 Gene3D G3DSA:1.25.40.10 165 216 2.0E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS24060 5f8c382533057ab3a5c947e5ec759052 227 Gene3D G3DSA:1.25.40.10 126 164 1.1E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS24060 5f8c382533057ab3a5c947e5ec759052 227 SMART SM00028 147 180 4.2E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS24060 5f8c382533057ab3a5c947e5ec759052 227 SMART SM00028 113 146 410.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS24060 5f8c382533057ab3a5c947e5ec759052 227 Gene3D G3DSA:1.25.40.10 1 125 0.096 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS19870 aa152e8c439c66c746b6428c6a08f6f0 332 Gene3D G3DSA:3.40.190.10 21 126 8.1E-17 T 29-03-2018 CVS48_RS19870 aa152e8c439c66c746b6428c6a08f6f0 332 SUPERFAMILY SSF53850 26 247 3.77E-37 T 29-03-2018 CVS48_RS19870 aa152e8c439c66c746b6428c6a08f6f0 332 SMART SM00062 26 246 0.0073 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS19870 aa152e8c439c66c746b6428c6a08f6f0 332 Pfam PF09084 NMT1/THI5 like 39 246 1.9E-24 T 29-03-2018 IPR015168 SsuA/THI5-like CVS48_RS19870 aa152e8c439c66c746b6428c6a08f6f0 332 Gene3D G3DSA:3.40.190.10 127 331 3.1E-25 T 29-03-2018 CVS48_RS10420 299fffafce8363c908fc2c526d701cf4 224 SUPERFAMILY SSF46785 13 82 3.85E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10420 299fffafce8363c908fc2c526d701cf4 224 Gene3D G3DSA:1.10.10.10 1 80 3.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10420 299fffafce8363c908fc2c526d701cf4 224 Pfam PF07729 FCD domain 88 207 5.2E-24 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS10420 299fffafce8363c908fc2c526d701cf4 224 Gene3D G3DSA:1.20.120.530 81 223 9.5E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS10420 299fffafce8363c908fc2c526d701cf4 224 SMART SM00345 20 78 6.4E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10420 299fffafce8363c908fc2c526d701cf4 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 78 8.7E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10420 299fffafce8363c908fc2c526d701cf4 224 SUPERFAMILY SSF48008 84 216 2.04E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS10420 299fffafce8363c908fc2c526d701cf4 224 SMART SM00895 88 209 3.3E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 Gene3D G3DSA:1.10.10.10 80 130 3.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 1 236 62.223 T 29-03-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 Pfam PF04542 Sigma-70 region 2 10 79 1.7E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 233 2.5E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 9 234 2.8E-79 T 29-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 34 47 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 PRINTS PR00046 Major sigma-70 factor signature 34 47 1.9E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 PRINTS PR00046 Major sigma-70 factor signature 58 66 1.9E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 PRINTS PR00046 Major sigma-70 factor signature 203 218 1.9E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 PRINTS PR00046 Major sigma-70 factor signature 218 229 1.9E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 PRINTS PR00046 Major sigma-70 factor signature 186 198 1.9E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 PIRSF PIRSF000770 3 249 2.3E-33 T 29-03-2018 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 SUPERFAMILY SSF88659 80 146 2.83E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 SUPERFAMILY SSF88946 7 79 1.19E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 Pfam PF04545 Sigma-70, region 4 182 230 1.0E-13 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 Gene3D G3DSA:1.10.10.10 142 236 2.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 SUPERFAMILY SSF88659 161 238 4.67E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 Pfam PF04539 Sigma-70 region 3 87 143 8.1E-12 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16760 0cd6d156d78e5dd1d67d5e7a8a6c4b72 251 Gene3D G3DSA:1.10.1740.10 3 76 7.4E-19 T 29-03-2018 CVS48_RS08045 c4751eb039fc4016464e717a849f86d9 470 Gene3D G3DSA:3.30.43.10 1 97 4.0E-27 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS08045 c4751eb039fc4016464e717a849f86d9 470 SUPERFAMILY SSF55103 222 470 1.42E-52 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS08045 c4751eb039fc4016464e717a849f86d9 470 Pfam PF01565 FAD binding domain 42 179 4.8E-36 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS08045 c4751eb039fc4016464e717a849f86d9 470 Gene3D G3DSA:1.10.45.10 430 469 1.3E-13 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CVS48_RS08045 c4751eb039fc4016464e717a849f86d9 470 SUPERFAMILY SSF56176 4 217 3.63E-72 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS08045 c4751eb039fc4016464e717a849f86d9 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 469 4.5E-49 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS08045 c4751eb039fc4016464e717a849f86d9 470 Gene3D G3DSA:3.30.465.10 98 218 7.6E-36 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS22815 c76b3baedeb7fccd411e113b5abe7195 586 SUPERFAMILY SSF52540 391 550 3.23E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22815 c76b3baedeb7fccd411e113b5abe7195 586 Gene3D G3DSA:3.40.50.300 370 579 6.7E-32 T 29-03-2018 CVS48_RS22815 c76b3baedeb7fccd411e113b5abe7195 586 SMART SM00382 64 381 0.0087 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22815 c76b3baedeb7fccd411e113b5abe7195 586 SMART SM00382 397 563 7.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22815 c76b3baedeb7fccd411e113b5abe7195 586 Pfam PF00005 ABC transporter 390 518 1.9E-16 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22815 c76b3baedeb7fccd411e113b5abe7195 586 Pfam PF00005 ABC transporter 66 205 1.8E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22815 c76b3baedeb7fccd411e113b5abe7195 586 Gene3D G3DSA:3.40.50.300 37 346 2.3E-42 T 29-03-2018 CVS48_RS22815 c76b3baedeb7fccd411e113b5abe7195 586 SUPERFAMILY SSF52540 51 251 4.89E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08595 3df1d2a3c4f53f2fe80b5628ec71119b 151 Gene3D G3DSA:2.30.180.10 19 149 1.7E-43 T 29-03-2018 IPR000782 FAS1 domain CVS48_RS08595 3df1d2a3c4f53f2fe80b5628ec71119b 151 SMART SM00554 55 151 7.9E-38 T 29-03-2018 IPR000782 FAS1 domain CVS48_RS08595 3df1d2a3c4f53f2fe80b5628ec71119b 151 SUPERFAMILY SSF82153 20 150 1.57E-44 T 29-03-2018 IPR000782 FAS1 domain CVS48_RS08595 3df1d2a3c4f53f2fe80b5628ec71119b 151 Pfam PF02469 Fasciclin domain 31 150 1.7E-39 T 29-03-2018 IPR000782 FAS1 domain CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 Gene3D G3DSA:1.10.439.10 42 190 2.7E-45 T 29-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 Gene3D G3DSA:1.10.1400.10 614 758 8.3E-24 T 29-03-2018 CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 SUPERFAMILY SSF56235 302 862 2.37E-206 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 SUPERFAMILY SSF56235 46 233 2.37E-206 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 Gene3D G3DSA:1.10.287.150 193 240 2.0E-18 T 29-03-2018 CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 Gene3D G3DSA:3.60.20.10 401 613 3.0E-36 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 Gene3D G3DSA:3.60.20.10 759 856 3.5E-5 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 Gene3D G3DSA:3.60.20.10 268 391 8.5E-19 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 PIRSF PIRSF001227 5 863 4.7E-116 T 29-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 CVS48_RS15905 a90b643cb0dcf7c3f1fb5145af8e1544 864 Pfam PF01804 Penicillin amidase 47 853 6.1E-147 T 29-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 SUPERFAMILY SSF50447 174 264 1.33E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 Gene3D G3DSA:2.40.30.10 272 353 2.7E-17 T 29-03-2018 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 SUPERFAMILY SSF46785 438 507 1.09E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 Pfam PF09107 Elongation factor SelB, winged helix 586 631 3.1E-18 T 29-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 Gene3D G3DSA:1.10.10.10 439 503 9.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 Pfam PF00009 Elongation factor Tu GTP binding domain 2 132 6.2E-27 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 Gene3D G3DSA:3.40.50.300 1 177 1.2E-24 T 29-03-2018 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 Gene3D G3DSA:2.40.30.10 178 265 1.2E-22 T 29-03-2018 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 SUPERFAMILY SSF46785 580 633 1.81E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 Gene3D G3DSA:1.10.10.10 574 632 3.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 PRINTS PR00315 GTP-binding elongation factor signature 70 81 2.4E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 PRINTS PR00315 GTP-binding elongation factor signature 54 64 2.4E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 PRINTS PR00315 GTP-binding elongation factor signature 2 15 2.4E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 Pfam PF09106 Elongation factor SelB, winged helix 449 503 1.6E-14 T 29-03-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 SUPERFAMILY SSF50465 272 367 1.71E-20 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 SUPERFAMILY SSF46785 511 573 2.99E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 632 1.6E-129 T 29-03-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 SUPERFAMILY SSF52540 2 194 2.13E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 Gene3D G3DSA:1.10.10.10 512 571 7.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04300 ebf83bb8a9b6b3e13885af27ddb77291 652 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 26 41 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CVS48_RS04365 3ba1bf8bcb5c8156744885b7ac06b069 483 Pfam PF11737 Protein of unknown function (DUF3300) 30 263 4.4E-91 T 29-03-2018 IPR021728 Protein of unknown function DUF3300 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 SUPERFAMILY SSF82693 40 134 1.91E-25 T 29-03-2018 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 SUPERFAMILY SSF82866 297 490 2.88E-51 T 29-03-2018 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 Gene3D G3DSA:1.20.1640.10 786 1005 8.6E-41 T 29-03-2018 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 SUPERFAMILY SSF82693 136 181 8.89E-24 T 29-03-2018 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 SUPERFAMILY SSF82693 267 323 8.89E-24 T 29-03-2018 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 SUPERFAMILY SSF82866 784 1009 2.49E-47 T 29-03-2018 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 SUPERFAMILY SSF82714 699 784 4.71E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 Gene3D G3DSA:3.30.2090.10 181 265 8.6E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 Gene3D G3DSA:3.30.2090.10 698 785 5.1E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 5.0E-79 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 5.0E-79 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 5.0E-79 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.0E-79 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 5.0E-79 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.0E-79 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 5.0E-79 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 5.0E-79 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 5.0E-79 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 Pfam PF00873 AcrB/AcrD/AcrF family 3 1003 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 Gene3D G3DSA:1.20.1640.10 280 500 1.7E-48 T 29-03-2018 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 SUPERFAMILY SSF82693 553 648 4.97E-20 T 29-03-2018 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 SUPERFAMILY SSF82714 182 264 7.59E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 Gene3D G3DSA:3.30.70.1430 555 650 3.9E-13 T 29-03-2018 CVS48_RS02830 b530164f6d05a87acdc42ea15dd1066e 1038 Gene3D G3DSA:3.30.70.1430 40 141 9.7E-29 T 29-03-2018 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 SUPERFAMILY SSF52540 961 1203 2.41E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 SMART SM00382 374 560 2.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 SMART SM00382 993 1179 2.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 641 1163 4.1E-100 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 SUPERFAMILY SSF90123 6 317 2.35E-47 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 SUPERFAMILY SSF52540 340 584 5.81E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 Pfam PF00005 ABC transporter 367 513 4.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 Pfam PF00005 ABC transporter 984 1133 6.3E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 ProSitePatterns PS00211 ABC transporters family signature. 1105 1119 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 Pfam PF00664 ABC transporter transmembrane region 21 280 2.0E-24 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 Pfam PF00664 ABC transporter transmembrane region 656 915 7.7E-21 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 SUPERFAMILY SSF90123 642 955 1.57E-52 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 Gene3D G3DSA:1.20.1560.10 635 955 2.6E-40 T 29-03-2018 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 Gene3D G3DSA:1.20.1560.10 5 317 3.0E-34 T 29-03-2018 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 Gene3D G3DSA:3.40.50.300 960 1208 1.2E-71 T 29-03-2018 CVS48_RS15910 05836e275539610bf8bbb9605635ab55 1216 Gene3D G3DSA:3.40.50.300 335 590 1.5E-70 T 29-03-2018 CVS48_RS03855 838a2f92f454fd470a1860e540cee796 132 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 67 81 1.7E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS03855 838a2f92f454fd470a1860e540cee796 132 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 81 97 1.7E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS03855 838a2f92f454fd470a1860e540cee796 132 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 97 109 1.7E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS03855 838a2f92f454fd470a1860e540cee796 132 Gene3D G3DSA:1.10.10.10 11 131 1.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03855 838a2f92f454fd470a1860e540cee796 132 SMART SM00421 64 121 4.1E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS03855 838a2f92f454fd470a1860e540cee796 132 SUPERFAMILY SSF46894 58 128 3.74E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS03855 838a2f92f454fd470a1860e540cee796 132 Pfam PF00196 Bacterial regulatory proteins, luxR family 66 120 6.9E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS13820 2a4a970ccd4a4969de1cbe6290fcc624 570 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 270 7.2E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13820 2a4a970ccd4a4969de1cbe6290fcc624 570 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 368 555 4.0E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13820 2a4a970ccd4a4969de1cbe6290fcc624 570 SUPERFAMILY SSF161098 15 277 1.78E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13820 2a4a970ccd4a4969de1cbe6290fcc624 570 Gene3D G3DSA:1.10.3720.10 13 278 2.6E-34 T 29-03-2018 CVS48_RS13820 2a4a970ccd4a4969de1cbe6290fcc624 570 Gene3D G3DSA:1.10.3720.10 297 562 5.2E-32 T 29-03-2018 CVS48_RS13820 2a4a970ccd4a4969de1cbe6290fcc624 570 SUPERFAMILY SSF161098 297 555 2.8E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 SUPERFAMILY SSF82693 40 131 3.49E-22 T 29-03-2018 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 SUPERFAMILY SSF82693 549 646 9.16E-15 T 29-03-2018 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 SUPERFAMILY SSF82693 136 182 1.62E-22 T 29-03-2018 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 SUPERFAMILY SSF82693 268 324 1.62E-22 T 29-03-2018 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 Gene3D G3DSA:1.20.1640.10 269 491 1.9E-46 T 29-03-2018 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 Gene3D G3DSA:1.20.1640.10 811 1009 1.1E-33 T 29-03-2018 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.3E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 3.3E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 3.3E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 3.3E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 PRINTS PR00702 Acriflavin resistance protein family signature 536 553 3.3E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.3E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 3.3E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 3.3E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 3.3E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 SUPERFAMILY SSF82866 790 1009 6.93E-44 T 29-03-2018 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 SUPERFAMILY SSF82866 290 490 3.53E-45 T 29-03-2018 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 Gene3D G3DSA:3.30.2090.10 698 787 2.3E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 Gene3D G3DSA:3.30.2090.10 181 268 1.6E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 SUPERFAMILY SSF82714 700 784 1.31E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 Pfam PF00873 AcrB/AcrD/AcrF family 5 1007 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 SUPERFAMILY SSF82714 183 266 2.35E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 Gene3D G3DSA:3.30.70.1430 40 143 2.5E-22 T 29-03-2018 CVS48_RS17670 13fec00d7aebdba4263719ba6773aab2 1028 Gene3D G3DSA:3.30.70.1430 552 650 1.4E-13 T 29-03-2018 CVS48_RS28820 86c448009632b5972070b0b783a3cf27 206 SMART SM00895 79 203 7.4E-15 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS28820 86c448009632b5972070b0b783a3cf27 206 Gene3D G3DSA:1.20.120.530 66 203 1.0E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS28820 86c448009632b5972070b0b783a3cf27 206 SMART SM00345 11 69 1.6E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS28820 86c448009632b5972070b0b783a3cf27 206 Gene3D G3DSA:1.10.10.10 2 65 2.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28820 86c448009632b5972070b0b783a3cf27 206 SUPERFAMILY SSF48008 78 201 2.88E-19 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS28820 86c448009632b5972070b0b783a3cf27 206 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 69 4.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS28820 86c448009632b5972070b0b783a3cf27 206 Pfam PF07729 FCD domain 79 201 5.7E-21 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS28820 86c448009632b5972070b0b783a3cf27 206 SUPERFAMILY SSF46785 11 73 6.67E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05615 5736cb7ee0d19a5bdf158b60911d04da 314 Gene3D G3DSA:3.40.190.10 89 176 1.6E-12 T 29-03-2018 CVS48_RS05615 5736cb7ee0d19a5bdf158b60911d04da 314 SUPERFAMILY SSF46785 5 84 7.55E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05615 5736cb7ee0d19a5bdf158b60911d04da 314 Gene3D G3DSA:3.40.190.10 177 266 2.6E-23 T 29-03-2018 CVS48_RS05615 5736cb7ee0d19a5bdf158b60911d04da 314 SUPERFAMILY SSF53850 90 298 1.1E-40 T 29-03-2018 CVS48_RS05615 5736cb7ee0d19a5bdf158b60911d04da 314 Pfam PF03466 LysR substrate binding domain 90 292 1.3E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS05615 5736cb7ee0d19a5bdf158b60911d04da 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 1.0E-12 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05615 5736cb7ee0d19a5bdf158b60911d04da 314 Gene3D G3DSA:1.10.10.10 3 84 2.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02050 0d184c508d726991fecc15e1950b82d4 108 Gene3D G3DSA:3.30.1360.20 13 100 1.0E-36 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CVS48_RS02050 0d184c508d726991fecc15e1950b82d4 108 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 14 94 1.3E-30 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CVS48_RS02050 0d184c508d726991fecc15e1950b82d4 108 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 96 23.774 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CVS48_RS02050 0d184c508d726991fecc15e1950b82d4 108 SUPERFAMILY SSF55248 14 96 1.96E-32 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 6.9E-90 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 6.9E-90 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 6.9E-90 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 6.9E-90 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 6.9E-90 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 6.9E-90 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 6.9E-90 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 6.9E-90 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 649 3.7E-221 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 646 2.8E-122 T 29-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 4.7E-53 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 4.7E-53 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 4.7E-53 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 639 652 4.7E-53 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 4.7E-53 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 4.7E-53 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 4.7E-53 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 CVS48_RS15720 6ee6e98f67e12a864000a83e42b948a5 674 Pfam PF01578 Cytochrome C assembly protein 89 295 1.8E-50 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 SUPERFAMILY SSF46785 1 112 9.33E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 Gene3D G3DSA:3.40.190.10 93 180 9.4E-22 T 29-03-2018 CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 Pfam PF03466 LysR substrate binding domain 88 293 2.1E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 SUPERFAMILY SSF53850 90 294 1.14E-35 T 29-03-2018 CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 Gene3D G3DSA:1.10.10.10 2 92 3.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26835 7065a843a15ac4618b99cccb76084dc9 306 Gene3D G3DSA:3.40.190.10 181 268 1.6E-14 T 29-03-2018 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Gene3D G3DSA:1.25.40.10 545 638 4.4E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Gene3D G3DSA:1.25.40.10 684 829 6.8E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Pfam PF13649 Methyltransferase domain 49 143 4.4E-10 T 29-03-2018 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Gene3D G3DSA:1.20.58.280 661 683 2.2E-6 T 29-03-2018 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Pfam PF10119 Predicted methyltransferase regulatory domain 227 296 2.9E-10 T 29-03-2018 IPR018773 Methyltransferase regulatory domain, predicted CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 SUPERFAMILY SSF53335 17 168 1.01E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 SUPERFAMILY SSF48452 557 729 9.96E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Pfam PF13844 Glycosyl transferase family 41 951 1122 3.7E-11 T 29-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Pfam PF13844 Glycosyl transferase family 41 773 920 6.2E-24 T 29-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Pfam PF13432 Tetratricopeptide repeat 598 652 7.3E-4 T 29-03-2018 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Gene3D G3DSA:3.40.50.2000 923 1106 3.4E-15 T 29-03-2018 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Pfam PF13181 Tetratricopeptide repeat 687 718 0.042 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 SMART SM00028 686 719 180.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 SMART SM00028 618 651 0.055 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 SMART SM00028 652 685 0.0077 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 SMART SM00028 584 617 28.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Gene3D G3DSA:1.20.58.280 639 660 0.0025 T 29-03-2018 CVS48_RS16750 01732f466286b0cb00bbc8de2f4b3d9b 1131 Gene3D G3DSA:3.40.50.150 5 309 2.7E-19 T 29-03-2018 CVS48_RS19665 ee17d2e1e3928ebd21c2b3d302e09e59 348 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 48 278 4.8E-30 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS19665 ee17d2e1e3928ebd21c2b3d302e09e59 348 Gene3D G3DSA:3.40.190.10 148 277 3.4E-5 T 29-03-2018 CVS48_RS19665 ee17d2e1e3928ebd21c2b3d302e09e59 348 SUPERFAMILY SSF53850 136 273 9.19E-7 T 29-03-2018 CVS48_RS07265 b5906b6c28fd59048e801ee85577476b 240 SMART SM00382 32 213 4.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS07265 b5906b6c28fd59048e801ee85577476b 240 Pfam PF00005 ABC transporter 23 165 3.3E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07265 b5906b6c28fd59048e801ee85577476b 240 SUPERFAMILY SSF52540 5 226 2.92E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07265 b5906b6c28fd59048e801ee85577476b 240 Gene3D G3DSA:3.40.50.300 1 238 4.1E-51 T 29-03-2018 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 Pfam PF01965 DJ-1/PfpI family 642 756 2.6E-13 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 PRINTS PR00067 Catalase signature 410 437 5.3E-70 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 PRINTS PR00067 Catalase signature 201 219 5.3E-70 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 PRINTS PR00067 Catalase signature 222 239 5.3E-70 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 PRINTS PR00067 Catalase signature 138 161 5.3E-70 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 PRINTS PR00067 Catalase signature 241 259 5.3E-70 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 PRINTS PR00067 Catalase signature 442 468 5.3E-70 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 ProSitePatterns PS00438 Catalase proximal active site signature. 161 177 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 PIRSF PIRSF038927 90 794 0.0 T 29-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 Gene3D G3DSA:3.40.50.880 639 793 1.1E-26 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 Pfam PF06628 Catalase-related immune-responsive 539 602 4.0E-21 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 Pfam PF00199 Catalase 125 509 3.0E-180 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 SUPERFAMILY SSF52317 640 772 3.11E-22 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 Gene3D G3DSA:2.40.180.10 96 480 1.4E-165 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 SMART SM01060 125 513 1.4E-279 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17645 f5c7ece88244b9f1d1acf4b4e975896e 795 SUPERFAMILY SSF56634 100 615 2.09E-222 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CVS48_RS17005 264832c2634d7a057b4e49237cae4dd2 110 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 27 109 4.2E-21 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CVS48_RS17005 264832c2634d7a057b4e49237cae4dd2 110 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 4 110 16.636 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CVS48_RS17005 264832c2634d7a057b4e49237cae4dd2 110 Pfam PF02049 Flagellar hook-basal body complex protein FliE 28 110 9.7E-26 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CVS48_RS17005 264832c2634d7a057b4e49237cae4dd2 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 74 90 1.4E-12 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CVS48_RS17005 264832c2634d7a057b4e49237cae4dd2 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 39 55 1.4E-12 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CVS48_RS17005 264832c2634d7a057b4e49237cae4dd2 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 95 108 1.4E-12 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CVS48_RS21085 ece43bdd597d59c00a9639342cab5dfe 423 Pfam PF00872 Transposase, Mutator family 37 391 1.4E-120 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS21085 ece43bdd597d59c00a9639342cab5dfe 423 ProSitePatterns PS01007 Transposases, Mutator family, signature. 251 275 - T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS10285 ece43bdd597d59c00a9639342cab5dfe 423 Pfam PF00872 Transposase, Mutator family 37 391 1.4E-120 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS10285 ece43bdd597d59c00a9639342cab5dfe 423 ProSitePatterns PS01007 Transposases, Mutator family, signature. 251 275 - T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS03605 ece43bdd597d59c00a9639342cab5dfe 423 Pfam PF00872 Transposase, Mutator family 37 391 1.4E-120 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS03605 ece43bdd597d59c00a9639342cab5dfe 423 ProSitePatterns PS01007 Transposases, Mutator family, signature. 251 275 - T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS09295 bea882cc0d79d57b78bc01379a822f3b 255 SUPERFAMILY SSF52540 22 249 1.63E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09295 bea882cc0d79d57b78bc01379a822f3b 255 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS09295 bea882cc0d79d57b78bc01379a822f3b 255 Gene3D G3DSA:3.40.50.300 9 254 4.8E-57 T 29-03-2018 CVS48_RS09295 bea882cc0d79d57b78bc01379a822f3b 255 Pfam PF00005 ABC transporter 39 183 1.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS09295 bea882cc0d79d57b78bc01379a822f3b 255 SMART SM00382 48 232 1.4E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 Gene3D G3DSA:3.30.565.10 292 448 2.8E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 430 1.7E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 SUPERFAMILY SSF47384 203 283 7.65E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 282 4.5E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 Pfam PF08521 Two-component sensor kinase N-terminal 4 142 4.5E-33 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 Gene3D G3DSA:1.10.287.130 211 281 3.8E-10 T 29-03-2018 CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 SUPERFAMILY SSF55874 290 441 1.83E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 SMART SM00388 220 285 2.2E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 SMART SM00387 334 447 3.8E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 385 1.0E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS06115 1cb4b4b249cb61f9eb1a041183db4014 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 1.0E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 Gene3D G3DSA:3.40.50.720 2 264 2.4E-48 T 29-03-2018 CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 9.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 9.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 9.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 SUPERFAMILY SSF51735 4 256 5.01E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 188 7.3E-5 T 29-03-2018 CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS16320 3faf064e8ee7da9f8855661b2bd0aae3 271 Pfam PF00106 short chain dehydrogenase 8 196 6.7E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS26095 5e403d66ab4ffa9fd6ccf6d613b01397 493 Pfam PF10150 Ribonuclease E/G family 126 397 4.3E-100 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CVS48_RS26095 5e403d66ab4ffa9fd6ccf6d613b01397 493 SUPERFAMILY SSF50249 45 130 5.04E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS26095 5e403d66ab4ffa9fd6ccf6d613b01397 493 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 19 430 1.3E-151 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CVS48_RS26095 5e403d66ab4ffa9fd6ccf6d613b01397 493 Gene3D G3DSA:2.40.50.140 39 129 2.3E-28 T 29-03-2018 CVS48_RS26095 5e403d66ab4ffa9fd6ccf6d613b01397 493 SMART SM00316 43 124 4.1E-9 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS23900 99d57446dca1b503795953bf17c81354 709 SUPERFAMILY SSF56935 43 709 1.14E-127 T 29-03-2018 CVS48_RS23900 99d57446dca1b503795953bf17c81354 709 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 83 709 1.3E-101 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS23900 99d57446dca1b503795953bf17c81354 709 Pfam PF07715 TonB-dependent Receptor Plug Domain 81 180 1.4E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS23900 99d57446dca1b503795953bf17c81354 709 Gene3D G3DSA:2.170.130.10 39 192 2.2E-27 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS23900 99d57446dca1b503795953bf17c81354 709 Pfam PF00593 TonB dependent receptor 257 708 9.2E-55 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS23900 99d57446dca1b503795953bf17c81354 709 Gene3D G3DSA:2.40.170.20 193 709 2.1E-76 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS26910 4abccf4d6a951b8ac5309b445cabc283 438 Pfam PF03486 HI0933-like protein 11 426 1.4E-103 T 29-03-2018 CVS48_RS26910 4abccf4d6a951b8ac5309b445cabc283 438 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 12 426 1.8E-80 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CVS48_RS26910 4abccf4d6a951b8ac5309b445cabc283 438 PRINTS PR00419 Adrenodoxin reductase family signature 34 47 2.1E-7 T 29-03-2018 CVS48_RS26910 4abccf4d6a951b8ac5309b445cabc283 438 PRINTS PR00419 Adrenodoxin reductase family signature 11 33 2.1E-7 T 29-03-2018 CVS48_RS26910 4abccf4d6a951b8ac5309b445cabc283 438 SUPERFAMILY SSF160996 211 373 6.67E-7 T 29-03-2018 CVS48_RS26910 4abccf4d6a951b8ac5309b445cabc283 438 SUPERFAMILY SSF51905 372 432 1.95E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS26910 4abccf4d6a951b8ac5309b445cabc283 438 SUPERFAMILY SSF51905 12 205 1.95E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS26910 4abccf4d6a951b8ac5309b445cabc283 438 Gene3D G3DSA:3.50.50.60 12 428 3.5E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS26910 4abccf4d6a951b8ac5309b445cabc283 438 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 32 433 1.1E-161 T 29-03-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 Pfam PF03466 LysR substrate binding domain 95 296 3.6E-15 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 Gene3D G3DSA:3.40.190.10 96 179 1.2E-7 T 29-03-2018 CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 SUPERFAMILY SSF46785 5 86 1.09E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 6.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 6.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 6.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 SUPERFAMILY SSF53850 91 296 1.09E-31 T 29-03-2018 CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.4E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 Gene3D G3DSA:1.10.10.10 1 92 3.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10805 008cd3867e26c78e8affdf27175251bc 302 Gene3D G3DSA:3.40.190.10 180 270 3.6E-11 T 29-03-2018 CVS48_RS13580 4c4e4bde538062d4d735801ce31f8f5e 165 SMART SM00989 102 164 4.1E-10 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR CVS48_RS13580 4c4e4bde538062d4d735801ce31f8f5e 165 Pfam PF02830 V4R domain 105 162 8.4E-11 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR CVS48_RS13580 4c4e4bde538062d4d735801ce31f8f5e 165 Gene3D G3DSA:3.30.1380.20 44 164 7.4E-17 T 29-03-2018 CVS48_RS13580 4c4e4bde538062d4d735801ce31f8f5e 165 SUPERFAMILY SSF111126 61 162 5.75E-16 T 29-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain CVS48_RS19255 3cc80c7b3e3497f7f344324b53b0a35b 326 SUPERFAMILY SSF53850 113 283 1.7E-15 T 29-03-2018 CVS48_RS19255 3cc80c7b3e3497f7f344324b53b0a35b 326 PIRSF PIRSF017082 1 324 3.0E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS19255 3cc80c7b3e3497f7f344324b53b0a35b 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 3.6E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS19255 3cc80c7b3e3497f7f344324b53b0a35b 326 Gene3D G3DSA:3.40.190.10 124 232 1.7E-14 T 29-03-2018 CVS48_RS28530 e09cb209d70a33efc67a1be774efda41 225 Gene3D G3DSA:3.40.50.300 1 224 5.1E-59 T 29-03-2018 CVS48_RS28530 e09cb209d70a33efc67a1be774efda41 225 SUPERFAMILY SSF52540 4 213 4.19E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28530 e09cb209d70a33efc67a1be774efda41 225 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS28530 e09cb209d70a33efc67a1be774efda41 225 Pfam PF00005 ABC transporter 20 161 3.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28530 e09cb209d70a33efc67a1be774efda41 225 SMART SM00382 26 206 4.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS14075 6f77181ce2257879f1481c208d88e5aa 409 Gene3D G3DSA:3.40.1580.10 18 186 8.6E-10 T 29-03-2018 CVS48_RS14075 6f77181ce2257879f1481c208d88e5aa 409 SUPERFAMILY SSF48403 250 338 1.41E-5 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS14075 6f77181ce2257879f1481c208d88e5aa 409 SMART SM00860 32 165 0.008 T 29-03-2018 IPR018958 Knr4/Smi1-like domain CVS48_RS14075 6f77181ce2257879f1481c208d88e5aa 409 Gene3D G3DSA:1.25.40.20 245 351 5.4E-6 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS12550 098e818ab5e2428438f07c98955bf674 169 Pfam PF04542 Sigma-70 region 2 15 81 3.6E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12550 098e818ab5e2428438f07c98955bf674 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 163 6.5E-20 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12550 098e818ab5e2428438f07c98955bf674 169 SUPERFAMILY SSF88659 105 164 3.4E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12550 098e818ab5e2428438f07c98955bf674 169 Gene3D G3DSA:1.10.1740.10 7 78 6.9E-18 T 29-03-2018 CVS48_RS12550 098e818ab5e2428438f07c98955bf674 169 Pfam PF08281 Sigma-70, region 4 111 164 2.0E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12550 098e818ab5e2428438f07c98955bf674 169 SUPERFAMILY SSF88946 13 100 1.14E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12550 098e818ab5e2428438f07c98955bf674 169 Gene3D G3DSA:1.10.10.10 79 167 7.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28975 035ff2e0a5dd5c9eb3fbdeee62bdce38 161 Pfam PF11578 Protein of unknown function (DUF3237) 13 160 2.4E-44 T 29-03-2018 IPR020915 Uncharacterised protein family UPF0311 CVS48_RS28975 035ff2e0a5dd5c9eb3fbdeee62bdce38 161 Gene3D G3DSA:2.40.160.20 4 161 3.7E-52 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CVS48_RS28975 035ff2e0a5dd5c9eb3fbdeee62bdce38 161 Hamap MF_00775 UPF0311 protein . 13 161 28.344 T 29-03-2018 IPR020915 Uncharacterised protein family UPF0311 CVS48_RS26550 a25f859f8b7f3714b6fd49ab333265fe 524 Gene3D G3DSA:3.30.450.20 161 288 1.6E-10 T 29-03-2018 CVS48_RS26550 a25f859f8b7f3714b6fd49ab333265fe 524 Pfam PF00990 Diguanylate cyclase, GGDEF domain 365 518 8.2E-43 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS26550 a25f859f8b7f3714b6fd49ab333265fe 524 Gene3D G3DSA:3.30.70.270 355 524 2.4E-53 T 29-03-2018 CVS48_RS26550 a25f859f8b7f3714b6fd49ab333265fe 524 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 362 521 7.2E-43 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS26550 a25f859f8b7f3714b6fd49ab333265fe 524 SUPERFAMILY SSF55073 370 521 4.39E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS26550 a25f859f8b7f3714b6fd49ab333265fe 524 SMART SM00267 351 523 2.6E-56 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS13310 b4a5283c082cb63d333c876073248fa4 206 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 19 203 8.8E-56 T 29-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CVS48_RS13310 b4a5283c082cb63d333c876073248fa4 206 SUPERFAMILY SSF159709 26 205 8.37E-57 T 29-03-2018 CVS48_RS13310 b4a5283c082cb63d333c876073248fa4 206 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 18 205 8.4E-62 T 29-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CVS48_RS13310 b4a5283c082cb63d333c876073248fa4 206 PIRSF PIRSF020680 11 206 8.3E-65 T 29-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 Pfam PF07729 FCD domain 164 288 3.8E-19 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 SMART SM00895 164 289 1.1E-16 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 Gene3D G3DSA:1.20.120.530 163 294 1.8E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 SUPERFAMILY SSF48008 161 292 1.96E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 74 1.3E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 Gene3D G3DSA:1.10.10.10 1 76 1.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 SMART SM00345 16 74 8.6E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 SMART SM00345 92 152 1.5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 SUPERFAMILY SSF46785 8 78 1.86E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28130 254262422e1797754efe9c694a59c48b 294 Gene3D G3DSA:1.10.10.10 83 162 6.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18700 6d1a9089b6119aab5f79bed259109973 332 Gene3D G3DSA:3.30.1780.10 4 135 7.5E-26 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CVS48_RS18700 6d1a9089b6119aab5f79bed259109973 332 Gene3D G3DSA:3.40.50.720 136 294 6.2E-24 T 29-03-2018 CVS48_RS18700 6d1a9089b6119aab5f79bed259109973 332 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 10 312 5.0E-47 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CVS48_RS18700 6d1a9089b6119aab5f79bed259109973 332 SUPERFAMILY SSF51735 5 321 9.81E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS18700 6d1a9089b6119aab5f79bed259109973 332 PIRSF PIRSF001439 3 322 2.9E-58 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CVS48_RS08960 989623e08ab716032031835e832df490 240 Pfam PF00005 ABC transporter 20 165 4.9E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS08960 989623e08ab716032031835e832df490 240 Gene3D G3DSA:3.40.50.300 1 240 3.5E-55 T 29-03-2018 CVS48_RS08960 989623e08ab716032031835e832df490 240 SUPERFAMILY SSF52540 4 237 2.0E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08960 989623e08ab716032031835e832df490 240 SMART SM00382 29 214 1.1E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08960 989623e08ab716032031835e832df490 240 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS08960 989623e08ab716032031835e832df490 240 PIRSF PIRSF039137 1 238 1.0E-101 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CVS48_RS17795 8ddbf147f0097ce3539af8fb6f0da538 529 SMART SM00267 348 514 5.1E-59 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS17795 8ddbf147f0097ce3539af8fb6f0da538 529 SUPERFAMILY SSF55073 364 515 4.32E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS17795 8ddbf147f0097ce3539af8fb6f0da538 529 Gene3D G3DSA:3.30.450.20 31 142 0.0089 T 29-03-2018 CVS48_RS17795 8ddbf147f0097ce3539af8fb6f0da538 529 Gene3D G3DSA:3.30.450.20 155 277 3.8E-9 T 29-03-2018 CVS48_RS17795 8ddbf147f0097ce3539af8fb6f0da538 529 Pfam PF00990 Diguanylate cyclase, GGDEF domain 360 510 6.2E-43 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS17795 8ddbf147f0097ce3539af8fb6f0da538 529 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 356 512 3.9E-45 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS17795 8ddbf147f0097ce3539af8fb6f0da538 529 Gene3D G3DSA:3.30.70.270 353 525 4.3E-53 T 29-03-2018 CVS48_RS19875 643372366ac0028fa9a1a1c7ed878e3a 256 SMART SM00382 27 208 7.5E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19875 643372366ac0028fa9a1a1c7ed878e3a 256 SUPERFAMILY SSF52540 3 213 2.47E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19875 643372366ac0028fa9a1a1c7ed878e3a 256 Gene3D G3DSA:3.40.50.300 1 239 4.2E-58 T 29-03-2018 CVS48_RS19875 643372366ac0028fa9a1a1c7ed878e3a 256 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS19875 643372366ac0028fa9a1a1c7ed878e3a 256 Pfam PF00005 ABC transporter 20 157 8.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07685 c9a90a06463661b6cef11a2f77ab3d8f 164 SUPERFAMILY SSF52833 22 162 1.86E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS07685 c9a90a06463661b6cef11a2f77ab3d8f 164 Pfam PF08534 Redoxin 25 149 3.4E-27 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CVS48_RS07685 c9a90a06463661b6cef11a2f77ab3d8f 164 Gene3D G3DSA:3.40.30.10 21 164 1.1E-36 T 29-03-2018 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 SMART SM00421 184 241 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 ProSitePatterns PS00622 LuxR-type HTH domain signature. 201 228 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 Gene3D G3DSA:1.10.10.10 186 245 2.0E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 Pfam PF00072 Response regulator receiver domain 44 157 7.2E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 SUPERFAMILY SSF52172 42 163 4.84E-22 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 Pfam PF00196 Bacterial regulatory proteins, luxR family 186 240 2.9E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 Gene3D G3DSA:3.40.50.2300 41 171 7.9E-24 T 29-03-2018 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 SMART SM00448 42 157 1.5E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 SUPERFAMILY SSF46894 178 243 4.08E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 201 2.5E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 217 229 2.5E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS15115 7efdbaf3254f888462dc7bc8823eefdf 247 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 217 2.5E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS17955 6f1170abdbb03e9f24a11a8dfdd91f20 387 SMART SM00116 319 366 0.0011 T 29-03-2018 IPR000644 CBS domain CVS48_RS17955 6f1170abdbb03e9f24a11a8dfdd91f20 387 SMART SM00116 247 295 7.9E-9 T 29-03-2018 IPR000644 CBS domain CVS48_RS17955 6f1170abdbb03e9f24a11a8dfdd91f20 387 Gene3D G3DSA:3.10.580.10 213 385 1.8E-27 T 29-03-2018 CVS48_RS17955 6f1170abdbb03e9f24a11a8dfdd91f20 387 Pfam PF00571 CBS domain 312 365 1.1E-6 T 29-03-2018 IPR000644 CBS domain CVS48_RS17955 6f1170abdbb03e9f24a11a8dfdd91f20 387 Pfam PF00571 CBS domain 241 292 2.6E-12 T 29-03-2018 IPR000644 CBS domain CVS48_RS17955 6f1170abdbb03e9f24a11a8dfdd91f20 387 SUPERFAMILY SSF54631 228 367 3.78E-27 T 29-03-2018 CVS48_RS17955 6f1170abdbb03e9f24a11a8dfdd91f20 387 Pfam PF04982 HPP family 54 173 1.3E-36 T 29-03-2018 IPR007065 HPP CVS48_RS28500 939ad11237da0e6e94afb91185a1c3c4 253 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS28500 939ad11237da0e6e94afb91185a1c3c4 253 SMART SM00382 33 219 7.4E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28500 939ad11237da0e6e94afb91185a1c3c4 253 Pfam PF00005 ABC transporter 27 174 5.7E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28500 939ad11237da0e6e94afb91185a1c3c4 253 Gene3D G3DSA:3.40.50.300 5 249 1.8E-51 T 29-03-2018 CVS48_RS28500 939ad11237da0e6e94afb91185a1c3c4 253 SUPERFAMILY SSF52540 7 244 5.22E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16810 ea2fa2df5d95c7fd0d060fcdb798f400 352 SUPERFAMILY SSF52172 1 108 5.83E-28 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS16810 ea2fa2df5d95c7fd0d060fcdb798f400 352 SMART SM00448 4 123 1.2E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS16810 ea2fa2df5d95c7fd0d060fcdb798f400 352 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 346 41.064 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS16810 ea2fa2df5d95c7fd0d060fcdb798f400 352 PIRSF PIRSF000876 1 349 7.2E-137 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS16810 ea2fa2df5d95c7fd0d060fcdb798f400 352 Gene3D G3DSA:3.40.50.2300 3 146 1.5E-26 T 29-03-2018 CVS48_RS16810 ea2fa2df5d95c7fd0d060fcdb798f400 352 SUPERFAMILY SSF52738 157 346 1.05E-70 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS16810 ea2fa2df5d95c7fd0d060fcdb798f400 352 Gene3D G3DSA:3.40.50.180 151 350 1.7E-77 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS16810 ea2fa2df5d95c7fd0d060fcdb798f400 352 Pfam PF00072 Response regulator receiver domain 6 108 2.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS16810 ea2fa2df5d95c7fd0d060fcdb798f400 352 Pfam PF01339 CheB methylesterase 162 341 7.5E-61 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS26490 95c213a7840b139a8bec41c85476fee0 546 PIRSF PIRSF500060 11 531 3.1E-241 T 29-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria CVS48_RS26490 95c213a7840b139a8bec41c85476fee0 546 SUPERFAMILY SSF51395 22 500 6.28E-137 T 29-03-2018 CVS48_RS26490 95c213a7840b139a8bec41c85476fee0 546 Gene3D G3DSA:3.20.20.70 83 495 1.0E-93 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS26490 95c213a7840b139a8bec41c85476fee0 546 Pfam PF01645 Conserved region in glutamate synthase 157 474 7.4E-81 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CVS48_RS26490 95c213a7840b139a8bec41c85476fee0 546 PIRSF PIRSF006429 8 541 4.1E-160 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 321 329 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 PRINTS PR00410 Phenol hydroxylase reductase family signature 119 128 1.9E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 PRINTS PR00410 Phenol hydroxylase reductase family signature 228 236 1.9E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 PRINTS PR00410 Phenol hydroxylase reductase family signature 56 68 1.9E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 PRINTS PR00410 Phenol hydroxylase reductase family signature 135 154 1.9E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 Pfam PF00970 Oxidoreductase FAD-binding domain 36 124 3.9E-15 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 Gene3D G3DSA:3.40.50.80 125 258 9.5E-25 T 29-03-2018 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 SUPERFAMILY SSF63380 23 124 1.86E-29 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 Gene3D G3DSA:2.40.30.10 25 124 8.5E-26 T 29-03-2018 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 Pfam PF00175 Oxidoreductase NAD-binding domain 136 240 2.1E-11 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 291 363 1.7E-13 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 135 154 4.8E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 75 82 4.8E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 172 183 4.8E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 228 236 4.8E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 SUPERFAMILY SSF54292 251 370 3.15E-28 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 Gene3D G3DSA:3.10.20.30 259 371 5.1E-29 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS01135 9073e912c971ab2a26cbfd27b544d203 371 SUPERFAMILY SSF52343 115 258 4.58E-32 T 29-03-2018 CVS48_RS00740 80c7fac199597e208b163e2b2fa3c14d 874 SUPERFAMILY SSF52540 82 214 1.84E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00740 80c7fac199597e208b163e2b2fa3c14d 874 SUPERFAMILY SSF52540 462 706 1.84E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00740 80c7fac199597e208b163e2b2fa3c14d 874 Gene3D G3DSA:3.40.50.300 80 716 3.1E-23 T 29-03-2018 CVS48_RS00740 80c7fac199597e208b163e2b2fa3c14d 874 Pfam PF13476 AAA domain 91 169 1.9E-9 T 29-03-2018 CVS48_RS19350 35f0fab7acfc8ef1cc9060b544c6dc51 669 Gene3D G3DSA:3.40.50.2000 122 273 0.0031 T 29-03-2018 CVS48_RS19350 35f0fab7acfc8ef1cc9060b544c6dc51 669 Pfam PF05159 Capsule polysaccharide biosynthesis protein 464 608 9.6E-30 T 29-03-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 CVS48_RS19350 35f0fab7acfc8ef1cc9060b544c6dc51 669 Pfam PF05159 Capsule polysaccharide biosynthesis protein 355 435 1.6E-10 T 29-03-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 CVS48_RS19350 35f0fab7acfc8ef1cc9060b544c6dc51 669 Pfam PF05159 Capsule polysaccharide biosynthesis protein 124 277 1.2E-32 T 29-03-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 CVS48_RS19350 35f0fab7acfc8ef1cc9060b544c6dc51 669 Pfam PF05159 Capsule polysaccharide biosynthesis protein 21 93 3.8E-9 T 29-03-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 Gene3D G3DSA:3.30.70.920 53 146 6.5E-24 T 29-03-2018 CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 Pfam PF01037 Lrp/AsnC ligand binding domain 67 139 1.2E-18 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 Gene3D G3DSA:1.10.10.10 1 52 2.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 7.6E-20 T 29-03-2018 CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.1E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.1E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.1E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 SUPERFAMILY SSF46785 1 81 7.81E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 SMART SM00344 1 110 4.4E-42 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS02390 728fdf67bf2069b29654d7bcb518a5d9 152 SUPERFAMILY SSF54909 61 149 1.61E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS28380 58a46da322ae6343a7e34516d4dbcdc0 967 SUPERFAMILY SSF50249 39 124 5.04E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS28380 58a46da322ae6343a7e34516d4dbcdc0 967 Hamap MF_00970 Ribonuclease E [rne]. 1 955 35.066 T 29-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 CVS48_RS28380 58a46da322ae6343a7e34516d4dbcdc0 967 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 7.9E-157 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CVS48_RS28380 58a46da322ae6343a7e34516d4dbcdc0 967 SMART SM00316 37 118 8.3E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS28380 58a46da322ae6343a7e34516d4dbcdc0 967 Pfam PF10150 Ribonuclease E/G family 120 389 5.2E-91 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CVS48_RS28380 58a46da322ae6343a7e34516d4dbcdc0 967 Gene3D G3DSA:2.40.50.140 32 123 1.6E-29 T 29-03-2018 CVS48_RS28380 58a46da322ae6343a7e34516d4dbcdc0 967 Pfam PF00575 S1 RNA binding domain 36 117 5.1E-11 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS00470 b2fb570dba1c321f6263cd92052f6737 348 Gene3D G3DSA:3.90.78.10 240 348 1.3E-41 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS00470 b2fb570dba1c321f6263cd92052f6737 348 SUPERFAMILY SSF56194 221 348 5.49E-48 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS00470 b2fb570dba1c321f6263cd92052f6737 348 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 225 348 1.6E-37 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS00470 b2fb570dba1c321f6263cd92052f6737 348 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 348 84.209 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS00470 b2fb570dba1c321f6263cd92052f6737 348 Gene3D G3DSA:3.30.465.10 84 237 2.9E-49 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS00470 b2fb570dba1c321f6263cd92052f6737 348 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 21 344 2.9E-66 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS00470 b2fb570dba1c321f6263cd92052f6737 348 SUPERFAMILY SSF56176 20 206 4.12E-36 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS00470 b2fb570dba1c321f6263cd92052f6737 348 Gene3D G3DSA:3.30.43.10 19 83 3.4E-14 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS00470 b2fb570dba1c321f6263cd92052f6737 348 Pfam PF01565 FAD binding domain 34 165 1.3E-17 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 SUPERFAMILY SSF158694 4 172 4.97E-49 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 Gene3D G3DSA:1.10.3330.10 3 178 6.2E-51 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 Pfam PF01546 Peptidase family M20/M25/M40 255 584 5.8E-25 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 Gene3D G3DSA:3.40.630.10 204 426 1.2E-36 T 29-03-2018 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 Gene3D G3DSA:3.40.630.10 427 590 5.7E-22 T 29-03-2018 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 17 171 1.2E-50 T 29-03-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 189 580 3.3E-99 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 Pfam PF09349 OHCU decarboxylase 9 170 2.0E-43 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 SUPERFAMILY SSF55031 391 504 1.22E-25 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 SUPERFAMILY SSF53187 513 588 2.54E-74 T 29-03-2018 CVS48_RS27840 e70f408b8b407f4038273f1a54bd9b0c 592 SUPERFAMILY SSF53187 183 401 2.54E-74 T 29-03-2018 CVS48_RS20990 ac061bb766bf1c066013da4689ca1e0e 241 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 94 101 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS20990 ac061bb766bf1c066013da4689ca1e0e 241 Pfam PF00484 Carbonic anhydrase 90 238 3.0E-39 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS20990 ac061bb766bf1c066013da4689ca1e0e 241 SMART SM00947 82 241 1.6E-47 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS20990 ac061bb766bf1c066013da4689ca1e0e 241 Gene3D G3DSA:3.40.1050.10 37 241 4.0E-54 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS20990 ac061bb766bf1c066013da4689ca1e0e 241 SUPERFAMILY SSF53056 50 241 2.75E-51 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS19640 27d69f0ef3ed22e9fca06eaad6d92b02 268 Gene3D G3DSA:3.40.1640.10 5 168 2.8E-70 T 29-03-2018 CVS48_RS19640 27d69f0ef3ed22e9fca06eaad6d92b02 268 Gene3D G3DSA:3.40.1640.10 205 268 2.6E-9 T 29-03-2018 CVS48_RS19640 27d69f0ef3ed22e9fca06eaad6d92b02 268 SUPERFAMILY SSF160920 13 260 1.44E-116 T 29-03-2018 CVS48_RS19640 27d69f0ef3ed22e9fca06eaad6d92b02 268 PIRSF PIRSF029755 3 268 4.0E-127 T 29-03-2018 IPR016938 Uncharacterised protein family UPF0317 CVS48_RS19640 27d69f0ef3ed22e9fca06eaad6d92b02 268 Hamap MF_01830 UPF0317 protein . 13 267 56.2 T 29-03-2018 IPR016938 Uncharacterised protein family UPF0317 CVS48_RS19640 27d69f0ef3ed22e9fca06eaad6d92b02 268 Pfam PF07286 Protein of unknown function (DUF1445) 117 259 2.5E-69 T 29-03-2018 IPR009906 D-glutamate cyclase CVS48_RS06110 c6d5bb34117770106cc7101e00f3d797 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 5.5E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS06110 c6d5bb34117770106cc7101e00f3d797 225 Gene3D G3DSA:3.40.50.2300 1 127 2.2E-32 T 29-03-2018 CVS48_RS06110 c6d5bb34117770106cc7101e00f3d797 225 SUPERFAMILY SSF52172 1 168 7.26E-35 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS06110 c6d5bb34117770106cc7101e00f3d797 225 SMART SM00862 146 219 1.8E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS06110 c6d5bb34117770106cc7101e00f3d797 225 SMART SM00448 1 113 1.7E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS06110 c6d5bb34117770106cc7101e00f3d797 225 Gene3D G3DSA:1.10.10.10 128 225 3.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06110 c6d5bb34117770106cc7101e00f3d797 225 Pfam PF00072 Response regulator receiver domain 3 113 2.5E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS09195 cceadbb7023630f0087b4df1941dbf7c 91 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 7.4E-50 T 29-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CVS48_RS09195 cceadbb7023630f0087b4df1941dbf7c 91 SUPERFAMILY SSF54909 1 91 2.79E-38 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS09195 cceadbb7023630f0087b4df1941dbf7c 91 PIRSF PIRSF001486 1 91 1.6E-46 T 29-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CVS48_RS09195 cceadbb7023630f0087b4df1941dbf7c 91 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 8.0E-24 T 29-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CVS48_RS09195 cceadbb7023630f0087b4df1941dbf7c 91 Pfam PF02426 Muconolactone delta-isomerase 1 89 1.2E-41 T 29-03-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 16 386 1.1E-114 T 29-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 371 384 - T 29-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 325 332 - T 29-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 4 386 1.3E-128 T 29-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 SUPERFAMILY SSF56542 229 427 1.2E-105 T 29-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 SUPERFAMILY SSF56542 7 119 1.2E-105 T 29-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 Gene3D G3DSA:3.90.770.10 4 120 9.8E-25 T 29-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 Gene3D G3DSA:3.90.770.10 227 390 2.2E-37 T 29-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 176 190 - T 29-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 77 97 2.4E-8 T 29-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 50 71 2.4E-8 T 29-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 313 334 2.4E-8 T 29-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 174 192 2.4E-8 T 29-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 SUPERFAMILY SSF55035 111 219 3.4E-31 T 29-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS17610 2e794e1acdb5e33be6a57ec19da75c1d 429 Gene3D G3DSA:3.30.70.420 121 219 2.4E-27 T 29-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 SMART SM00388 696 763 9.5E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Pfam PF13493 Domain of unknown function (DUF4118) 434 539 2.8E-28 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 SUPERFAMILY SSF55781 540 681 1.14E-5 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Pfam PF13492 GAF domain 578 677 2.1E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 27 235 6.2E-92 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Gene3D G3DSA:3.40.50.620 232 390 3.0E-11 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 SUPERFAMILY SSF52402 258 359 1.84E-6 T 29-03-2018 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 811 918 7.1E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Pfam PF00512 His Kinase A (phospho-acceptor) domain 697 762 6.7E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 SUPERFAMILY SSF55874 753 920 1.13E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 SMART SM00387 807 919 3.6E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 SUPERFAMILY SSF47384 691 763 2.75E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Gene3D G3DSA:1.10.287.130 688 757 3.5E-15 T 29-03-2018 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Gene3D G3DSA:3.30.565.10 758 919 4.0E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Gene3D G3DSA:1.20.120.620 433 532 2.3E-26 T 29-03-2018 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 PRINTS PR00344 Bacterial sensor protein C-terminal signature 903 916 3.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 PRINTS PR00344 Bacterial sensor protein C-terminal signature 844 858 3.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 PRINTS PR00344 Bacterial sensor protein C-terminal signature 862 872 3.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 PRINTS PR00344 Bacterial sensor protein C-terminal signature 877 895 3.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Gene3D G3DSA:3.40.50.300 26 158 5.1E-19 T 29-03-2018 CVS48_RS00315 3cd1894f9ea09bca4445b14913d43e31 932 Gene3D G3DSA:3.30.450.40 537 687 8.3E-8 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS18075 5f4939c3621aa0c1b55517a370b97af6 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 56 69 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CVS48_RS18075 5f4939c3621aa0c1b55517a370b97af6 338 Gene3D G3DSA:3.40.190.10 136 265 8.6E-17 T 29-03-2018 CVS48_RS18075 5f4939c3621aa0c1b55517a370b97af6 338 SUPERFAMILY SSF53850 25 257 3.33E-45 T 29-03-2018 CVS48_RS18075 5f4939c3621aa0c1b55517a370b97af6 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 253 2.2E-30 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS18075 5f4939c3621aa0c1b55517a370b97af6 338 SMART SM00062 34 263 1.0E-41 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS18075 5f4939c3621aa0c1b55517a370b97af6 338 Gene3D G3DSA:3.40.190.10 24 135 4.6E-12 T 29-03-2018 CVS48_RS14400 f222e98c1a368ff660c4cdd94219beb7 329 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CVS48_RS14400 f222e98c1a368ff660c4cdd94219beb7 329 SUPERFAMILY SSF50129 6 148 1.53E-38 T 29-03-2018 IPR011032 GroES-like CVS48_RS14400 f222e98c1a368ff660c4cdd94219beb7 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 90 5.2E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS14400 f222e98c1a368ff660c4cdd94219beb7 329 SMART SM00829 15 326 1.7E-36 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS14400 f222e98c1a368ff660c4cdd94219beb7 329 SUPERFAMILY SSF51735 115 271 6.16E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS14400 f222e98c1a368ff660c4cdd94219beb7 329 Gene3D G3DSA:3.90.180.10 2 136 1.4E-37 T 29-03-2018 CVS48_RS14400 f222e98c1a368ff660c4cdd94219beb7 329 Pfam PF00107 Zinc-binding dehydrogenase 155 261 1.1E-27 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS14400 f222e98c1a368ff660c4cdd94219beb7 329 Gene3D G3DSA:3.40.50.720 137 312 3.1E-31 T 29-03-2018 CVS48_RS21075 1180d6546ce237dc48450f1a48646195 725 Pfam PF00270 DEAD/DEAH box helicase 104 213 1.2E-7 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS21075 1180d6546ce237dc48450f1a48646195 725 Pfam PF00271 Helicase conserved C-terminal domain 361 433 3.2E-7 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS21075 1180d6546ce237dc48450f1a48646195 725 SUPERFAMILY SSF52540 270 443 8.54E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21075 1180d6546ce237dc48450f1a48646195 725 SMART SM00490 352 433 1.0E-6 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS21075 1180d6546ce237dc48450f1a48646195 725 Gene3D G3DSA:3.40.50.300 278 443 3.2E-14 T 29-03-2018 CVS48_RS21075 1180d6546ce237dc48450f1a48646195 725 SUPERFAMILY SSF52540 63 210 6.41E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21075 1180d6546ce237dc48450f1a48646195 725 SMART SM00487 97 284 4.1E-6 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS21075 1180d6546ce237dc48450f1a48646195 725 Gene3D G3DSA:3.40.50.300 73 268 1.7E-15 T 29-03-2018 CVS48_RS28465 bb427178b5f274470f04900edbc95ca5 257 Gene3D G3DSA:3.40.50.300 2 251 9.5E-57 T 29-03-2018 CVS48_RS28465 bb427178b5f274470f04900edbc95ca5 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 4.0E-7 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS28465 bb427178b5f274470f04900edbc95ca5 257 Pfam PF00005 ABC transporter 22 177 3.3E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28465 bb427178b5f274470f04900edbc95ca5 257 SUPERFAMILY SSF52540 4 247 1.17E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28465 bb427178b5f274470f04900edbc95ca5 257 SMART SM00382 30 224 1.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 Gene3D G3DSA:2.30.40.10 42 111 1.8E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 Pfam PF01979 Amidohydrolase family 103 231 4.3E-5 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 Pfam PF01979 Amidohydrolase family 395 505 1.7E-9 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 Gene3D G3DSA:3.20.20.140 112 436 1.8E-32 T 29-03-2018 CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 Gene3D G3DSA:2.30.40.10 437 524 0.0026 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 SUPERFAMILY SSF51556 106 267 5.96E-47 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 SUPERFAMILY SSF51556 311 335 5.96E-47 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 SUPERFAMILY SSF51556 364 454 5.96E-47 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 SUPERFAMILY SSF51338 39 107 7.44E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS08865 10b8a66f2dcdc68f16200c33e2590cf5 552 SUPERFAMILY SSF51338 453 480 7.44E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS04010 ee0f9d67448496871895e7a2ffeb9109 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 318 5.9E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS04010 ee0f9d67448496871895e7a2ffeb9109 325 SUPERFAMILY SSF161098 90 304 2.78E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS04010 ee0f9d67448496871895e7a2ffeb9109 325 Gene3D G3DSA:1.10.3720.10 4 308 5.7E-40 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 PRINTS PR00941 Cadmium-transporting ATPase signature 344 360 1.7E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 PRINTS PR00941 Cadmium-transporting ATPase signature 262 282 1.7E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 PRINTS PR00941 Cadmium-transporting ATPase signature 363 377 1.7E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 212 787 1.9E-121 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 227 787 2.1E-175 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 SUPERFAMILY SSF56784 478 497 8.25E-52 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 SUPERFAMILY SSF56784 538 784 8.25E-52 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 250 491 9.4E-40 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 580 768 1.1E-34 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 SUPERFAMILY SSF81653 280 378 6.41E-27 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 SUPERFAMILY SSF55008 88 149 1.54E-9 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 Gene3D G3DSA:3.40.1110.10 497 603 5.7E-26 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 Gene3D G3DSA:3.40.50.1000 604 757 1.0E-34 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 Pfam PF00702 haloacid dehalogenase-like hydrolase 476 698 9.2E-38 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 Gene3D G3DSA:3.30.70.100 90 157 1.6E-5 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 Gene3D G3DSA:1.20.1110.10 168 496 7.3E-37 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 SUPERFAMILY SSF81665 228 281 1.96E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 SUPERFAMILY SSF81665 379 471 1.96E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 481 487 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 708 720 1.7E-24 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 684 703 1.7E-24 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 479 493 1.7E-24 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 1.7E-24 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 627 637 1.7E-24 T 29-03-2018 CVS48_RS16040 348b6273d2f86b75fbd8f188f37639d7 792 Pfam PF00122 E1-E2 ATPase 278 459 2.4E-56 T 29-03-2018 CVS48_RS05995 977bc5ec6f198c32c13d5bf814599517 303 Gene3D G3DSA:3.40.190.10 2 150 1.6E-24 T 29-03-2018 CVS48_RS05995 977bc5ec6f198c32c13d5bf814599517 303 SMART SM00062 36 270 4.6E-37 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS05995 977bc5ec6f198c32c13d5bf814599517 303 SUPERFAMILY SSF53850 1 271 3.33E-52 T 29-03-2018 CVS48_RS05995 977bc5ec6f198c32c13d5bf814599517 303 Gene3D G3DSA:3.40.190.10 151 277 4.5E-11 T 29-03-2018 CVS48_RS05995 977bc5ec6f198c32c13d5bf814599517 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 268 2.4E-39 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS23665 1ef888a3548aa7044c191e5ee73fb44b 325 Gene3D G3DSA:1.10.3720.10 3 312 4.0E-28 T 29-03-2018 CVS48_RS23665 1ef888a3548aa7044c191e5ee73fb44b 325 SUPERFAMILY SSF161098 109 306 1.8E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS23665 1ef888a3548aa7044c191e5ee73fb44b 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 323 5.4E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS24650 57f3b9b2d60b273f3c5053df50bf8f9b 429 SUPERFAMILY SSF56349 107 413 3.53E-32 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS24650 57f3b9b2d60b273f3c5053df50bf8f9b 429 Gene3D G3DSA:1.10.443.10 223 414 1.0E-20 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS24650 57f3b9b2d60b273f3c5053df50bf8f9b 429 Pfam PF00589 Phage integrase family 225 402 5.1E-6 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS24650 57f3b9b2d60b273f3c5053df50bf8f9b 429 Pfam PF13356 Arm DNA-binding domain 20 87 7.4E-7 T 29-03-2018 IPR025166 Integrase, DNA-binding domain CVS48_RS24650 57f3b9b2d60b273f3c5053df50bf8f9b 429 Gene3D G3DSA:1.10.150.130 97 213 7.3E-6 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 Gene3D G3DSA:1.10.520.20 2 108 3.5E-27 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.9E-23 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 PRINTS PR00125 ATP synthase delta subunit signature 137 152 1.9E-23 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 PRINTS PR00125 ATP synthase delta subunit signature 76 87 1.9E-23 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 PRINTS PR00125 ATP synthase delta subunit signature 152 170 1.9E-23 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 PRINTS PR00125 ATP synthase delta subunit signature 87 101 1.9E-23 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 SUPERFAMILY SSF47928 3 107 6.8E-24 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 177 1.4E-40 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 179 20.096 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04105 9a8d66d9e80bf9c17f7a8a2a118df3e8 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 177 4.9E-50 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 Pfam PF03466 LysR substrate binding domain 87 293 5.1E-28 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 SUPERFAMILY SSF53850 88 297 2.72E-30 T 29-03-2018 CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.0E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 Gene3D G3DSA:3.40.190.10 183 268 9.5E-7 T 29-03-2018 CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 Gene3D G3DSA:1.10.10.10 1 79 1.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 SUPERFAMILY SSF46785 1 111 1.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25050 c43215ff22ccbeed943572028ec0d2f8 308 Gene3D G3DSA:3.40.190.10 80 182 2.0E-22 T 29-03-2018 CVS48_RS14695 803133edac249042ee0a7931fd2ccb47 428 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 21 414 5.7E-115 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CVS48_RS14695 803133edac249042ee0a7931fd2ccb47 428 Pfam PF04551 GcpE protein 36 415 2.1E-111 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CVS48_RS14695 803133edac249042ee0a7931fd2ccb47 428 SUPERFAMILY SSF56014 314 422 3.1E-8 T 29-03-2018 CVS48_RS14695 803133edac249042ee0a7931fd2ccb47 428 PIRSF PIRSF004640 15 424 1.2E-126 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CVS48_RS14695 803133edac249042ee0a7931fd2ccb47 428 Gene3D G3DSA:3.20.20.70 37 297 2.8E-5 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS14695 803133edac249042ee0a7931fd2ccb47 428 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 23 417 28.211 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CVS48_RS21875 6025e329c823d5490d0b13b3ff563b68 259 SUPERFAMILY SSF52096 3 256 1.37E-67 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS21875 6025e329c823d5490d0b13b3ff563b68 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 256 1.5E-51 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS21875 6025e329c823d5490d0b13b3ff563b68 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS21875 6025e329c823d5490d0b13b3ff563b68 259 Gene3D G3DSA:3.90.226.10 1 259 2.7E-65 T 29-03-2018 CVS48_RS07225 01264b76ccd99e87ec60f6be0a6999f4 342 SMART SM00729 105 314 2.7E-15 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CVS48_RS07225 01264b76ccd99e87ec60f6be0a6999f4 342 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 36 94 1.5E-8 T 29-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CVS48_RS07225 01264b76ccd99e87ec60f6be0a6999f4 342 Hamap MF_00206 Lipoyl synthase [lipA]. 57 342 154.241 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CVS48_RS07225 01264b76ccd99e87ec60f6be0a6999f4 342 Gene3D G3DSA:3.20.20.70 34 341 1.1E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS07225 01264b76ccd99e87ec60f6be0a6999f4 342 TIGRFAM TIGR00510 lipA: lipoyl synthase 54 336 1.1E-130 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CVS48_RS07225 01264b76ccd99e87ec60f6be0a6999f4 342 Pfam PF04055 Radical SAM superfamily 112 271 2.6E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS07225 01264b76ccd99e87ec60f6be0a6999f4 342 PIRSF PIRSF005963 3 342 3.2E-130 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CVS48_RS07225 01264b76ccd99e87ec60f6be0a6999f4 342 SUPERFAMILY SSF102114 74 338 1.44E-66 T 29-03-2018 CVS48_RS21765 8d3ca42fef1f4b6cfbe890958d7a23c9 673 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 656 673 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS21765 8d3ca42fef1f4b6cfbe890958d7a23c9 673 SUPERFAMILY SSF56935 40 673 1.03E-131 T 29-03-2018 CVS48_RS21765 8d3ca42fef1f4b6cfbe890958d7a23c9 673 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 54 - T 29-03-2018 IPR010916 TonB box, conserved site CVS48_RS21765 8d3ca42fef1f4b6cfbe890958d7a23c9 673 Pfam PF00593 TonB dependent receptor 204 672 8.8E-63 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS21765 8d3ca42fef1f4b6cfbe890958d7a23c9 673 Gene3D G3DSA:2.40.170.20 180 673 4.3E-85 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS21765 8d3ca42fef1f4b6cfbe890958d7a23c9 673 Gene3D G3DSA:2.170.130.10 37 177 8.3E-37 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS21765 8d3ca42fef1f4b6cfbe890958d7a23c9 673 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 170 5.8E-27 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS15680 450214c5899be02b847632d956e2fbe5 289 Pfam PF05726 Pirin C-terminal cupin domain 184 285 3.5E-28 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 CVS48_RS15680 450214c5899be02b847632d956e2fbe5 289 SUPERFAMILY SSF51182 2 288 4.93E-84 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS15680 450214c5899be02b847632d956e2fbe5 289 PIRSF PIRSF006232 2 289 4.6E-89 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CVS48_RS15680 450214c5899be02b847632d956e2fbe5 289 Pfam PF02678 Pirin 26 129 2.1E-35 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CVS48_RS15680 450214c5899be02b847632d956e2fbe5 289 Gene3D G3DSA:2.60.120.10 1 259 1.2E-81 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 Gene3D G3DSA:3.30.450.20 263 385 2.7E-20 T 29-03-2018 CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 Pfam PF13426 PAS domain 160 251 1.3E-7 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 Pfam PF13426 PAS domain 278 374 3.4E-7 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 SUPERFAMILY SSF46894 411 483 1.94E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 423 437 6.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 437 453 6.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 453 465 6.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 Pfam PF13188 PAS domain 14 56 6.1E-4 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 Gene3D G3DSA:1.10.10.10 386 487 2.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 SUPERFAMILY SSF55785 24 145 7.15E-8 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 Pfam PF00196 Bacterial regulatory proteins, luxR family 422 477 6.5E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 SUPERFAMILY SSF55785 138 250 6.28E-14 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 Gene3D G3DSA:3.30.450.20 1 142 7.7E-11 T 29-03-2018 CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 Gene3D G3DSA:3.30.450.20 143 262 1.5E-18 T 29-03-2018 CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 SMART SM00091 141 208 0.022 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 SMART SM00091 13 74 11.0 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 SMART SM00091 266 332 1.9 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 SMART SM00086 335 375 0.001 T 29-03-2018 IPR001610 PAC motif CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 262 381 1.7E-11 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 140 261 5.7E-12 T 29-03-2018 IPR000014 PAS domain CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 SMART SM00421 420 477 1.9E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS12910 3420bca43f5f151990b4d3fe5e9e0a59 497 SUPERFAMILY SSF55785 253 373 1.92E-17 T 29-03-2018 IPR000014 PAS domain CVS48_RS13415 c7ecbff375551d029760cfbf9c5cdc82 190 Gene3D G3DSA:1.20.1550.10 1 169 2.6E-35 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CVS48_RS13415 c7ecbff375551d029760cfbf9c5cdc82 190 SUPERFAMILY SSF158442 16 127 1.15E-22 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CVS48_RS13415 c7ecbff375551d029760cfbf9c5cdc82 190 Pfam PF02600 Disulfide bond formation protein DsbB 12 97 2.1E-12 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CVS48_RS22950 86d838f79ef8364f01d95eb096b17cc1 409 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 168 393 1.5E-119 T 29-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 CVS48_RS22950 86d838f79ef8364f01d95eb096b17cc1 409 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 170 392 4.6E-107 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related CVS48_RS22950 86d838f79ef8364f01d95eb096b17cc1 409 Gene3D G3DSA:3.40.50.300 125 399 2.6E-103 T 29-03-2018 CVS48_RS22950 86d838f79ef8364f01d95eb096b17cc1 409 SUPERFAMILY SSF52540 199 383 1.51E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13885 416d837c86d60d9db5949d9b92f1778d 346 SUPERFAMILY SSF53850 27 337 7.69E-96 T 29-03-2018 CVS48_RS13885 416d837c86d60d9db5949d9b92f1778d 346 Gene3D G3DSA:3.40.190.10 159 338 1.6E-25 T 29-03-2018 CVS48_RS13885 416d837c86d60d9db5949d9b92f1778d 346 Gene3D G3DSA:3.40.190.10 24 158 2.3E-30 T 29-03-2018 CVS48_RS13885 416d837c86d60d9db5949d9b92f1778d 346 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 27 334 2.6E-125 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CVS48_RS13885 416d837c86d60d9db5949d9b92f1778d 346 PIRSF PIRSF002756 5 339 5.7E-109 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CVS48_RS13885 416d837c86d60d9db5949d9b92f1778d 346 Pfam PF12849 PBP superfamily domain 24 307 1.2E-60 T 29-03-2018 IPR024370 PBP domain CVS48_RS24435 523ae520c9ad039dd1b42946f577ddbd 480 SMART SM00220 13 266 2.6E-17 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CVS48_RS24435 523ae520c9ad039dd1b42946f577ddbd 480 Pfam PF00069 Protein kinase domain 14 257 3.7E-23 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CVS48_RS24435 523ae520c9ad039dd1b42946f577ddbd 480 SUPERFAMILY SSF56112 7 259 5.6E-38 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS24435 523ae520c9ad039dd1b42946f577ddbd 480 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 41 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CVS48_RS24435 523ae520c9ad039dd1b42946f577ddbd 480 Gene3D G3DSA:1.10.510.10 109 287 4.4E-24 T 29-03-2018 CVS48_RS24435 523ae520c9ad039dd1b42946f577ddbd 480 Gene3D G3DSA:3.30.200.20 2 108 7.6E-11 T 29-03-2018 CVS48_RS24435 523ae520c9ad039dd1b42946f577ddbd 480 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 Gene3D G3DSA:3.60.20.10 7 148 5.1E-30 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 Gene3D G3DSA:3.60.20.10 149 235 4.2E-20 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 PIRSF PIRSF000485 1 482 8.2E-155 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 45.268 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 Gene3D G3DSA:3.40.50.2020 236 451 3.6E-38 T 29-03-2018 CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 Pfam PF13522 Glutamine amidotransferase domain 64 210 9.8E-16 T 29-03-2018 CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 SUPERFAMILY SSF53271 252 483 5.88E-73 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 Pfam PF00156 Phosphoribosyl transferase domain 285 395 4.6E-8 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 1.8E-156 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CVS48_RS17085 661eaa58cd846b07a96230c09ef90f09 506 SUPERFAMILY SSF56235 2 259 3.0E-68 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS17465 38213d38dcb7e215256a274fd4a69a8d 105 Pfam PF01381 Helix-turn-helix 20 67 1.4E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS17465 38213d38dcb7e215256a274fd4a69a8d 105 SMART SM00530 19 72 1.0E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS17465 38213d38dcb7e215256a274fd4a69a8d 105 SUPERFAMILY SSF47413 9 68 3.66E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS17465 38213d38dcb7e215256a274fd4a69a8d 105 Gene3D G3DSA:1.10.260.40 6 82 5.1E-14 T 29-03-2018 CVS48_RS19220 a87d2fd89ff7423da2ed372f597ea248 161 Pfam PF09722 Protein of unknown function (DUF2384) 109 158 8.8E-14 T 29-03-2018 IPR024467 Domain of unknown function DUF2384 CVS48_RS19220 a87d2fd89ff7423da2ed372f597ea248 161 TIGRFAM TIGR02293 TAS_TIGR02293: putative toxin-antitoxin system antitoxin component, TIGR02293 family 32 161 1.1E-47 T 29-03-2018 IPR011979 Conserved hypothetical protein CHP02293 CVS48_RS04330 eff1fda18380ea148d0dcfe28419e60b 196 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 49 67 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CVS48_RS04330 eff1fda18380ea148d0dcfe28419e60b 196 SMART SM00926 44 105 3.8E-22 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS04330 eff1fda18380ea148d0dcfe28419e60b 196 SUPERFAMILY SSF53706 37 196 1.83E-52 T 29-03-2018 CVS48_RS04330 eff1fda18380ea148d0dcfe28419e60b 196 Gene3D G3DSA:3.40.50.740 110 196 5.2E-11 T 29-03-2018 CVS48_RS04330 eff1fda18380ea148d0dcfe28419e60b 196 Gene3D G3DSA:2.20.25.90 37 109 4.1E-22 T 29-03-2018 CVS48_RS04330 eff1fda18380ea148d0dcfe28419e60b 196 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 104 7.1E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS04330 eff1fda18380ea148d0dcfe28419e60b 196 Pfam PF00384 Molybdopterin oxidoreductase 108 147 1.3E-5 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS13645 1a83bb2eab7b42106c870e62d2d81aea 341 Gene3D G3DSA:3.40.50.720 153 333 1.2E-34 T 29-03-2018 CVS48_RS13645 1a83bb2eab7b42106c870e62d2d81aea 341 SUPERFAMILY SSF50129 310 338 3.96E-57 T 29-03-2018 IPR011032 GroES-like CVS48_RS13645 1a83bb2eab7b42106c870e62d2d81aea 341 SUPERFAMILY SSF50129 3 146 3.96E-57 T 29-03-2018 IPR011032 GroES-like CVS48_RS13645 1a83bb2eab7b42106c870e62d2d81aea 341 Gene3D G3DSA:3.90.180.10 2 152 8.4E-55 T 29-03-2018 CVS48_RS13645 1a83bb2eab7b42106c870e62d2d81aea 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 134 5.9E-34 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS13645 1a83bb2eab7b42106c870e62d2d81aea 341 Pfam PF00107 Zinc-binding dehydrogenase 179 303 5.4E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS13645 1a83bb2eab7b42106c870e62d2d81aea 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS13645 1a83bb2eab7b42106c870e62d2d81aea 341 SMART SM00829 14 338 2.0E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS13645 1a83bb2eab7b42106c870e62d2d81aea 341 SUPERFAMILY SSF51735 143 308 2.93E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 14 950 0.0 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 SUPERFAMILY SSF53383 14 437 2.16E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 Gene3D G3DSA:3.90.1150.10 337 439 9.0E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 Gene3D G3DSA:3.40.640.10 525 771 2.3E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 Gene3D G3DSA:3.40.640.10 92 336 9.6E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 SUPERFAMILY SSF53383 479 886 1.75E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 SUPERFAMILY SSF53383 929 951 1.75E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 Gene3D G3DSA:3.90.1150.10 772 904 2.7E-46 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 5 956 25.418 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 Pfam PF02347 Glycine cleavage system P-protein 447 733 2.5E-14 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CVS48_RS10590 05e6cd5655c7cef746751bcbbedd0f06 957 Pfam PF02347 Glycine cleavage system P-protein 14 435 4.1E-180 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CVS48_RS16960 ae9f364ba646ff3d8ae1e89db2ddd016 184 SUPERFAMILY SSF101801 98 180 1.7E-26 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CVS48_RS16960 ae9f364ba646ff3d8ae1e89db2ddd016 184 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 98 173 3.6E-34 T 29-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CVS48_RS16960 ae9f364ba646ff3d8ae1e89db2ddd016 184 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 101 171 6.7E-26 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CVS48_RS16960 ae9f364ba646ff3d8ae1e89db2ddd016 184 Gene3D G3DSA:2.30.330.10 90 182 1.0E-30 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CVS48_RS16960 ae9f364ba646ff3d8ae1e89db2ddd016 184 PRINTS PR00956 Flagellar motor switch protein FliN signature 101 117 5.1E-30 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CVS48_RS16960 ae9f364ba646ff3d8ae1e89db2ddd016 184 PRINTS PR00956 Flagellar motor switch protein FliN signature 134 147 5.1E-30 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CVS48_RS16960 ae9f364ba646ff3d8ae1e89db2ddd016 184 PRINTS PR00956 Flagellar motor switch protein FliN signature 118 134 5.1E-30 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CVS48_RS16960 ae9f364ba646ff3d8ae1e89db2ddd016 184 PRINTS PR00956 Flagellar motor switch protein FliN signature 147 162 5.1E-30 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 1.1E-17 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 1.1E-17 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 1.1E-17 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 1 13 1.1E-17 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 113 122 1.1E-17 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 Gene3D G3DSA:3.50.50.60 261 322 3.7E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 SUPERFAMILY SSF51905 11 201 3.28E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 7.8E-23 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 7.8E-23 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 7.8E-23 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 7.8E-23 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 7.8E-23 T 29-03-2018 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 291 8.2E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 SUPERFAMILY SSF51905 152 316 5.28E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 Gene3D G3DSA:3.50.50.60 5 129 6.0E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS13055 ce058266ece5ee24a2df231dbd1e2048 421 Gene3D G3DSA:3.50.50.60 130 260 1.4E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS20640 32a6de87ff01f64c72eaff623a93dbfd 467 Pfam PF01546 Peptidase family M20/M25/M40 86 454 1.3E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS20640 32a6de87ff01f64c72eaff623a93dbfd 467 Pfam PF07687 Peptidase dimerisation domain 198 356 2.0E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS20640 32a6de87ff01f64c72eaff623a93dbfd 467 Gene3D G3DSA:3.40.630.10 8 203 6.8E-35 T 29-03-2018 CVS48_RS20640 32a6de87ff01f64c72eaff623a93dbfd 467 SUPERFAMILY SSF53187 371 456 1.77E-55 T 29-03-2018 CVS48_RS20640 32a6de87ff01f64c72eaff623a93dbfd 467 SUPERFAMILY SSF53187 6 200 1.77E-55 T 29-03-2018 CVS48_RS20640 32a6de87ff01f64c72eaff623a93dbfd 467 Gene3D G3DSA:3.30.70.360 204 366 1.3E-43 T 29-03-2018 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 TIGRFAM TIGR00763 lon: endopeptidase La 15 783 3.4E-302 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 SUPERFAMILY SSF52540 317 597 1.28E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 Gene3D G3DSA:3.40.50.300 286 507 7.0E-30 T 29-03-2018 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 SMART SM00464 13 205 9.1E-76 T 29-03-2018 IPR003111 Lon, substrate-binding domain CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 685 704 3.5E-56 T 29-03-2018 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 738 756 3.5E-56 T 29-03-2018 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 715 734 3.5E-56 T 29-03-2018 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 358 377 3.5E-56 T 29-03-2018 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 607 623 3.5E-56 T 29-03-2018 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 688 696 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 SUPERFAMILY SSF54211 607 782 6.83E-57 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 SUPERFAMILY SSF88697 13 204 1.81E-53 T 29-03-2018 IPR015947 PUA-like domain CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 SMART SM00382 350 494 2.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 Gene3D G3DSA:3.30.230.10 589 803 4.7E-69 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 Gene3D G3DSA:1.10.4060.10 125 214 2.8E-31 T 29-03-2018 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 Hamap MF_01973 Lon protease [lon]. 14 784 70.253 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 582 784 4.6E-95 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 PIRSF PIRSF001174 2 787 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 491 7.5E-18 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 14 203 4.7E-41 T 29-03-2018 IPR003111 Lon, substrate-binding domain CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 Gene3D G3DSA:1.10.8.60 508 588 4.8E-32 T 29-03-2018 CVS48_RS21960 2ea86c6a1a8f4dbdb8ce120e98950b0b 816 Gene3D G3DSA:2.30.130.40 1 121 1.4E-32 T 29-03-2018 CVS48_RS00210 ef8d77408e4653edef08b457cb5d6aff 519 Gene3D G3DSA:3.90.76.10 63 162 6.4E-26 T 29-03-2018 CVS48_RS00210 ef8d77408e4653edef08b457cb5d6aff 519 PIRSF PIRSF002741 4 515 6.7E-66 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS00210 ef8d77408e4653edef08b457cb5d6aff 519 Gene3D G3DSA:3.40.190.10 163 300 1.8E-28 T 29-03-2018 CVS48_RS00210 ef8d77408e4653edef08b457cb5d6aff 519 Gene3D G3DSA:3.10.105.10 301 487 3.1E-26 T 29-03-2018 CVS48_RS00210 ef8d77408e4653edef08b457cb5d6aff 519 SUPERFAMILY SSF53850 35 515 1.05E-95 T 29-03-2018 CVS48_RS00210 ef8d77408e4653edef08b457cb5d6aff 519 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 423 3.8E-67 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 Gene3D G3DSA:3.40.50.1370 169 309 4.3E-46 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 Gene3D G3DSA:3.40.50.1370 11 168 4.5E-64 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 151 1.4E-50 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 SUPERFAMILY SSF53671 11 308 1.7E-102 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 88 101 4.9E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 225 235 4.9E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 55 69 4.9E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 128 142 4.9E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 287 298 4.9E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 11 309 78.853 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 2.0E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 273 296 2.0E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 2.0E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 261 270 2.0E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 159 306 4.4E-47 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CVS48_RS26345 97a082eff8380631f846f7363466a6e3 312 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 12 308 2.7E-113 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS25035 1eed5c135c3a967e137453443f60108a 352 Pfam PF00355 Rieske [2Fe-2S] domain 18 98 8.5E-18 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS25035 1eed5c135c3a967e137453443f60108a 352 SUPERFAMILY SSF50022 5 129 2.1E-32 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS25035 1eed5c135c3a967e137453443f60108a 352 Gene3D G3DSA:2.102.10.10 3 119 1.7E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS25035 1eed5c135c3a967e137453443f60108a 352 Gene3D G3DSA:3.90.380.10 120 332 3.0E-38 T 29-03-2018 CVS48_RS25035 1eed5c135c3a967e137453443f60108a 352 SUPERFAMILY SSF55961 128 329 4.0E-47 T 29-03-2018 CVS48_RS01275 d34dd20b24b749f8622ef035e863c629 193 Gene3D G3DSA:2.20.70.10 17 46 4.4E-16 T 29-03-2018 CVS48_RS01275 d34dd20b24b749f8622ef035e863c629 193 ProSitePatterns PS00893 Nudix box signature. 85 106 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CVS48_RS01275 d34dd20b24b749f8622ef035e863c629 193 Pfam PF14803 Nudix N-terminal 18 50 1.1E-17 T 29-03-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 CVS48_RS01275 d34dd20b24b749f8622ef035e863c629 193 SUPERFAMILY SSF55811 18 178 6.36E-41 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS01275 d34dd20b24b749f8622ef035e863c629 193 Gene3D G3DSA:3.90.79.10 47 183 6.8E-32 T 29-03-2018 CVS48_RS01275 d34dd20b24b749f8622ef035e863c629 193 Pfam PF00293 NUDIX domain 53 156 6.4E-14 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CVS48_RS28905 363a1d118fb7bad7784d263ba47ec6ce 361 SMART SM00421 301 358 8.4E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS28905 363a1d118fb7bad7784d263ba47ec6ce 361 Pfam PF00196 Bacterial regulatory proteins, luxR family 307 358 2.3E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS28905 363a1d118fb7bad7784d263ba47ec6ce 361 SUPERFAMILY SSF46894 299 358 1.16E-9 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS28905 363a1d118fb7bad7784d263ba47ec6ce 361 Gene3D G3DSA:1.10.10.10 138 360 5.7E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 Gene3D G3DSA:3.20.20.10 25 253 1.1E-50 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 SUPERFAMILY SSF50621 242 409 2.72E-54 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 6 409 5.0E-123 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 173 186 5.8E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 42 60 5.8E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 367 380 5.8E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 256 275 5.8E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 62 74 5.8E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 Gene3D G3DSA:2.40.37.10 254 410 6.1E-45 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 PRINTS PR01181 Diaminopimelate decarboxylase signature 148 157 9.7E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 PRINTS PR01181 Diaminopimelate decarboxylase signature 284 302 9.7E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 PRINTS PR01181 Diaminopimelate decarboxylase signature 377 399 9.7E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 PRINTS PR01181 Diaminopimelate decarboxylase signature 60 77 9.7E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 37 266 2.7E-54 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 5 410 38.434 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 42 60 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 SUPERFAMILY SSF51419 16 268 2.49E-61 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 205 220 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CVS48_RS22510 05c01497f851a39813c97dbb8eec83b8 410 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 20 367 7.7E-23 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CVS48_RS17850 c4cca985dc5f4667bf1cdd6ca1824a44 350 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 128 303 1.4E-59 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS17850 c4cca985dc5f4667bf1cdd6ca1824a44 350 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 213 235 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CVS48_RS17850 c4cca985dc5f4667bf1cdd6ca1824a44 350 Gene3D G3DSA:3.40.50.720 22 133 4.8E-23 T 29-03-2018 CVS48_RS17850 c4cca985dc5f4667bf1cdd6ca1824a44 350 Gene3D G3DSA:3.40.50.720 134 306 1.5E-56 T 29-03-2018 CVS48_RS17850 c4cca985dc5f4667bf1cdd6ca1824a44 350 SUPERFAMILY SSF52283 71 147 2.98E-20 T 29-03-2018 CVS48_RS17850 c4cca985dc5f4667bf1cdd6ca1824a44 350 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 74 335 5.7E-24 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CVS48_RS17850 c4cca985dc5f4667bf1cdd6ca1824a44 350 SUPERFAMILY SSF51735 121 304 8.33E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS26195 ef81e6e6be6f3db87cbf2beea66ac849 649 Pfam PF05506 Domain of unknown function (DUF756) 458 544 2.2E-21 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CVS48_RS26195 ef81e6e6be6f3db87cbf2beea66ac849 649 Gene3D G3DSA:3.40.720.10 106 427 3.8E-20 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS26195 ef81e6e6be6f3db87cbf2beea66ac849 649 Pfam PF04185 Phosphoesterase family 35 421 3.2E-114 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 CVS48_RS26195 ef81e6e6be6f3db87cbf2beea66ac849 649 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 14 445 4.8E-189 T 29-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CVS48_RS05975 f60aa4bc0cf7a33aa45a05df1f08b370 352 Pfam PF01212 Beta-eliminating lyase 15 295 1.3E-79 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CVS48_RS05975 f60aa4bc0cf7a33aa45a05df1f08b370 352 Gene3D G3DSA:3.90.1150.10 257 352 7.0E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS05975 f60aa4bc0cf7a33aa45a05df1f08b370 352 SUPERFAMILY SSF53383 14 350 4.08E-93 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS05975 f60aa4bc0cf7a33aa45a05df1f08b370 352 Gene3D G3DSA:3.40.640.10 9 256 7.0E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS05975 f60aa4bc0cf7a33aa45a05df1f08b370 352 PIRSF PIRSF017617 5 352 4.0E-103 T 29-03-2018 IPR023603 Threonine aldolase CVS48_RS00650 a776f52cd62755dfb4bf9fe09562d930 164 Pfam PF04002 RadC-like JAB domain 45 162 1.2E-38 T 29-03-2018 IPR025657 RadC-like JAB domain CVS48_RS00650 a776f52cd62755dfb4bf9fe09562d930 164 SUPERFAMILY SSF102712 52 141 3.27E-5 T 29-03-2018 CVS48_RS00650 a776f52cd62755dfb4bf9fe09562d930 164 Gene3D G3DSA:3.40.140.10 39 164 1.5E-41 T 29-03-2018 CVS48_RS09890 6780265ef113e38967af93d379e4a403 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS09890 6780265ef113e38967af93d379e4a403 493 Gene3D G3DSA:3.40.605.10 1 271 8.1E-104 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS09890 6780265ef113e38967af93d379e4a403 493 Pfam PF00171 Aldehyde dehydrogenase family 13 479 1.0E-175 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS09890 6780265ef113e38967af93d379e4a403 493 Gene3D G3DSA:3.40.309.10 272 465 3.0E-72 T 29-03-2018 CVS48_RS09890 6780265ef113e38967af93d379e4a403 493 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS09890 6780265ef113e38967af93d379e4a403 493 SUPERFAMILY SSF53720 5 483 4.97E-171 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS16605 e696e5fa223b83a752ab7b69cdd1b6d4 387 SUPERFAMILY SSF53822 15 380 8.75E-87 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS16605 e696e5fa223b83a752ab7b69cdd1b6d4 387 Gene3D G3DSA:3.40.50.2300 2 139 1.2E-15 T 29-03-2018 CVS48_RS16605 e696e5fa223b83a752ab7b69cdd1b6d4 387 Gene3D G3DSA:3.40.50.2300 140 318 2.0E-35 T 29-03-2018 CVS48_RS16605 e696e5fa223b83a752ab7b69cdd1b6d4 387 Pfam PF13433 Periplasmic binding protein domain 14 377 3.4E-133 T 29-03-2018 CVS48_RS26620 81839964422c91550b816fda7f34cf51 291 SUPERFAMILY SSF53187 21 287 2.98E-87 T 29-03-2018 CVS48_RS26620 81839964422c91550b816fda7f34cf51 291 Pfam PF05013 N-formylglutamate amidohydrolase 24 257 6.0E-68 T 29-03-2018 IPR007709 N-formylglutamate amidohydrolase CVS48_RS26620 81839964422c91550b816fda7f34cf51 291 Gene3D G3DSA:3.40.630.40 12 290 2.0E-80 T 29-03-2018 CVS48_RS16720 f4c62d98b83de15c98aa14324b4519cb 251 Gene3D G3DSA:3.40.50.150 7 237 1.7E-9 T 29-03-2018 CVS48_RS16720 f4c62d98b83de15c98aa14324b4519cb 251 Pfam PF04989 Cephalosporin hydroxylase 46 249 1.0E-89 T 29-03-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 CVS48_RS16720 f4c62d98b83de15c98aa14324b4519cb 251 SUPERFAMILY SSF53335 28 249 3.73E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS29030 0c6d43e7a6e4dfad4d3b67a2de8f93c4 248 Pfam PF00121 Triosephosphate isomerase 10 245 4.8E-85 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS29030 0c6d43e7a6e4dfad4d3b67a2de8f93c4 248 Gene3D G3DSA:3.20.20.70 5 248 8.4E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS29030 0c6d43e7a6e4dfad4d3b67a2de8f93c4 248 ProSitePatterns PS00171 Triosephosphate isomerase active site. 168 178 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS29030 0c6d43e7a6e4dfad4d3b67a2de8f93c4 248 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 7 248 37.88 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS29030 0c6d43e7a6e4dfad4d3b67a2de8f93c4 248 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 10 240 2.2E-60 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS29030 0c6d43e7a6e4dfad4d3b67a2de8f93c4 248 SUPERFAMILY SSF51351 6 246 1.83E-86 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS19365 54762ed9e4521be8ca6a9a0a50d95637 219 Gene3D G3DSA:3.40.50.300 1 219 4.5E-40 T 29-03-2018 CVS48_RS19365 54762ed9e4521be8ca6a9a0a50d95637 219 Pfam PF00005 ABC transporter 23 154 4.5E-16 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19365 54762ed9e4521be8ca6a9a0a50d95637 219 SMART SM00382 31 202 7.1E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19365 54762ed9e4521be8ca6a9a0a50d95637 219 SUPERFAMILY SSF52540 1 213 9.82E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS11445 e087adb0321091abdb4b6665c09bb2d8 299 Gene3D G3DSA:1.10.10.60 190 244 2.7E-5 T 29-03-2018 CVS48_RS11445 e087adb0321091abdb4b6665c09bb2d8 299 SUPERFAMILY SSF51215 45 176 8.11E-11 T 29-03-2018 CVS48_RS11445 e087adb0321091abdb4b6665c09bb2d8 299 Gene3D G3DSA:1.10.10.60 247 296 1.9E-13 T 29-03-2018 CVS48_RS11445 e087adb0321091abdb4b6665c09bb2d8 299 Pfam PF12833 Helix-turn-helix domain 214 292 1.7E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS11445 e087adb0321091abdb4b6665c09bb2d8 299 Gene3D G3DSA:2.60.120.280 14 181 2.2E-22 T 29-03-2018 CVS48_RS11445 e087adb0321091abdb4b6665c09bb2d8 299 SUPERFAMILY SSF46689 248 294 1.21E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS11445 e087adb0321091abdb4b6665c09bb2d8 299 SMART SM00342 208 291 2.2E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS11605 f029fb4d8322423719dcec3312a69d82 289 SUPERFAMILY SSF51556 19 287 3.33E-65 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS11605 f029fb4d8322423719dcec3312a69d82 289 Gene3D G3DSA:3.20.20.140 8 289 1.5E-36 T 29-03-2018 CVS48_RS11605 f029fb4d8322423719dcec3312a69d82 289 Pfam PF04909 Amidohydrolase 23 287 2.4E-36 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS17145 547325c8933d4a2ebd7481f6c16aea96 285 Pfam PF01148 Cytidylyltransferase family 4 280 8.8E-53 T 29-03-2018 CVS48_RS17145 547325c8933d4a2ebd7481f6c16aea96 285 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 242 268 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CVS48_RS08745 84cc5af0d2e66f1bc401b38765bcfd81 246 SMART SM00382 29 213 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08745 84cc5af0d2e66f1bc401b38765bcfd81 246 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 214 236 6.3E-11 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS08745 84cc5af0d2e66f1bc401b38765bcfd81 246 Pfam PF00005 ABC transporter 21 164 9.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS08745 84cc5af0d2e66f1bc401b38765bcfd81 246 SUPERFAMILY SSF52540 4 237 4.07E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08745 84cc5af0d2e66f1bc401b38765bcfd81 246 Gene3D G3DSA:3.40.50.300 1 244 2.5E-59 T 29-03-2018 CVS48_RS26025 1c552d4f0210d928f89a09f654e3f5fb 471 Pfam PF01425 Amidase 27 450 1.5E-76 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS26025 1c552d4f0210d928f89a09f654e3f5fb 471 SUPERFAMILY SSF75304 3 458 3.01E-106 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS26025 1c552d4f0210d928f89a09f654e3f5fb 471 ProSitePatterns PS00571 Amidases signature. 153 184 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CVS48_RS26025 1c552d4f0210d928f89a09f654e3f5fb 471 Gene3D G3DSA:3.90.1300.10 1 464 2.3E-103 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS15575 a601f4a94399052312ec3574ad024889 236 SUPERFAMILY SSF51206 16 151 3.67E-21 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CVS48_RS15575 a601f4a94399052312ec3574ad024889 236 Pfam PF13545 Crp-like helix-turn-helix domain 160 230 1.2E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS15575 a601f4a94399052312ec3574ad024889 236 Gene3D G3DSA:2.60.120.10 7 155 7.2E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS15575 a601f4a94399052312ec3574ad024889 236 Pfam PF00027 Cyclic nucleotide-binding domain 42 126 4.7E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS15575 a601f4a94399052312ec3574ad024889 236 SUPERFAMILY SSF46785 157 232 9.73E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15575 a601f4a94399052312ec3574ad024889 236 Gene3D G3DSA:1.10.10.10 156 232 1.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 5.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 5.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 5.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 1.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 1.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 SUPERFAMILY SSF51735 5 236 5.0E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 Gene3D G3DSA:3.40.50.720 4 239 9.2E-66 T 29-03-2018 CVS48_RS15875 06870abe9ea60fd478dab0e178512c41 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 235 1.4E-46 T 29-03-2018 CVS48_RS23370 f3ffb622a3ce47f37749f07f707bac57 323 SUPERFAMILY SSF53850 91 284 4.98E-13 T 29-03-2018 CVS48_RS23370 f3ffb622a3ce47f37749f07f707bac57 323 PIRSF PIRSF017082 1 323 4.9E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23370 f3ffb622a3ce47f37749f07f707bac57 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 4.1E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23370 f3ffb622a3ce47f37749f07f707bac57 323 Gene3D G3DSA:3.40.190.10 138 233 8.2E-10 T 29-03-2018 CVS48_RS23370 f3ffb622a3ce47f37749f07f707bac57 323 Gene3D G3DSA:3.40.190.10 30 137 0.42 T 29-03-2018 CVS48_RS09925 d886feec64c7ed5f40a5eed458dff739 280 Gene3D G3DSA:3.40.190.10 33 194 4.0E-31 T 29-03-2018 CVS48_RS09925 d886feec64c7ed5f40a5eed458dff739 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 268 7.3E-32 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS09925 d886feec64c7ed5f40a5eed458dff739 280 SUPERFAMILY SSF53850 34 268 1.51E-38 T 29-03-2018 CVS48_RS09925 d886feec64c7ed5f40a5eed458dff739 280 SMART SM00062 44 273 1.0E-25 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS09925 d886feec64c7ed5f40a5eed458dff739 280 Gene3D G3DSA:3.40.190.10 195 277 0.002 T 29-03-2018 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 PRINTS PR00974 Ribosomal protein S18 family signature 53 60 6.3E-15 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 PRINTS PR00974 Ribosomal protein S18 family signature 61 75 6.3E-15 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 PRINTS PR00974 Ribosomal protein S18 family signature 43 53 6.3E-15 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 PRINTS PR00974 Ribosomal protein S18 family signature 75 85 6.3E-15 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 SUPERFAMILY SSF46911 14 89 1.57E-27 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 TIGRFAM TIGR00165 S18: ribosomal protein bS18 20 87 6.2E-33 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 36 85 7.0E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 7 88 20.184 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 Pfam PF01084 Ribosomal protein S18 34 83 2.2E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 Gene3D G3DSA:4.10.640.10 4 90 3.5E-29 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26990 00a1d4e325050f9a9ee2e93040ab8e38 90 ProSitePatterns PS00057 Ribosomal protein S18 signature. 36 59 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 257 1.9E-49 T 29-03-2018 CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 Gene3D G3DSA:3.40.50.720 2 260 2.1E-58 T 29-03-2018 CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 4.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 4.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 4.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 4.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 4.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 SUPERFAMILY SSF51735 13 257 6.11E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 3.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15980 d1541189c1293ad8e22ebe98720b7eee 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 3.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS17575 e235520249f36d584bb9f1276ee2e2e5 242 Gene3D G3DSA:1.10.10.10 18 82 2.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17575 e235520249f36d584bb9f1276ee2e2e5 242 SUPERFAMILY SSF55781 77 239 1.96E-27 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS17575 e235520249f36d584bb9f1276ee2e2e5 242 Pfam PF01614 Bacterial transcriptional regulator 178 234 8.7E-6 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS17575 e235520249f36d584bb9f1276ee2e2e5 242 Pfam PF09339 IclR helix-turn-helix domain 22 71 6.4E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS17575 e235520249f36d584bb9f1276ee2e2e5 242 SUPERFAMILY SSF46785 20 90 4.18E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17575 e235520249f36d584bb9f1276ee2e2e5 242 SMART SM00346 20 109 1.8E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS17575 e235520249f36d584bb9f1276ee2e2e5 242 Gene3D G3DSA:3.30.450.40 167 242 1.9E-9 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS17575 e235520249f36d584bb9f1276ee2e2e5 242 Gene3D G3DSA:3.30.450.40 89 164 6.4E-15 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS00635 38835bd846f58b108be1015fdce2cb87 464 TIGRFAM TIGR03755 conj_TIGR03755: integrating conjugative element protein, PFL_4711 family 48 457 8.2E-177 T 29-03-2018 IPR021204 Integrating conjugative element protein, PFL4711 CVS48_RS21930 a1ea880e0f2f220d887bc6157309b9cd 403 PIRSF PIRSF005572 3 383 9.3E-136 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CVS48_RS21930 a1ea880e0f2f220d887bc6157309b9cd 403 SUPERFAMILY SSF53383 5 390 1.73E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS21930 a1ea880e0f2f220d887bc6157309b9cd 403 Pfam PF00266 Aminotransferase class-V 6 367 1.3E-88 T 29-03-2018 IPR000192 Aminotransferase class V domain CVS48_RS21930 a1ea880e0f2f220d887bc6157309b9cd 403 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 4 403 1.2E-227 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 CVS48_RS21930 a1ea880e0f2f220d887bc6157309b9cd 403 Gene3D G3DSA:3.40.640.10 2 236 5.7E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS21930 a1ea880e0f2f220d887bc6157309b9cd 403 Gene3D G3DSA:3.90.1150.10 237 403 9.8E-53 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS21930 a1ea880e0f2f220d887bc6157309b9cd 403 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 2 394 55.334 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 CVS48_RS21930 a1ea880e0f2f220d887bc6157309b9cd 403 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 196 215 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CVS48_RS20840 043648125724c0e59634e937e0f992fa 116 SUPERFAMILY SSF101386 1 115 5.67E-38 T 29-03-2018 CVS48_RS20840 043648125724c0e59634e937e0f992fa 116 PIRSF PIRSF029826 1 116 2.0E-44 T 29-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CVS48_RS20840 043648125724c0e59634e937e0f992fa 116 Gene3D G3DSA:1.10.4010.10 2 112 3.8E-25 T 29-03-2018 CVS48_RS20840 043648125724c0e59634e937e0f992fa 116 Pfam PF12643 MazG-like family 36 116 1.6E-14 T 29-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CVS48_RS14525 75938e70ccd2b09ffc5a8cfe84bd39c7 134 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 118 4.0E-63 T 29-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS14525 75938e70ccd2b09ffc5a8cfe84bd39c7 134 Hamap MF_01255 L-ectoine synthase [ectC]. 1 128 38.888 T 29-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS14525 75938e70ccd2b09ffc5a8cfe84bd39c7 134 SUPERFAMILY SSF51182 1 128 1.49E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS14525 75938e70ccd2b09ffc5a8cfe84bd39c7 134 Gene3D G3DSA:2.60.120.10 2 134 5.7E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS14525 75938e70ccd2b09ffc5a8cfe84bd39c7 134 Pfam PF06339 Ectoine synthase 1 126 8.3E-56 T 29-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS16125 96ddab9664f135069bb96a1220972fba 687 Gene3D G3DSA:3.40.50.620 360 674 2.8E-51 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS16125 96ddab9664f135069bb96a1220972fba 687 Pfam PF02540 NAD synthase 352 526 4.0E-25 T 29-03-2018 IPR022310 NAD/GMP synthase CVS48_RS16125 96ddab9664f135069bb96a1220972fba 687 SUPERFAMILY SSF52402 620 652 1.72E-63 T 29-03-2018 CVS48_RS16125 96ddab9664f135069bb96a1220972fba 687 SUPERFAMILY SSF52402 330 580 1.72E-63 T 29-03-2018 CVS48_RS16125 96ddab9664f135069bb96a1220972fba 687 PIRSF PIRSF006630 11 674 1.8E-156 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CVS48_RS16125 96ddab9664f135069bb96a1220972fba 687 Gene3D G3DSA:3.60.110.10 8 359 1.9E-82 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS16125 96ddab9664f135069bb96a1220972fba 687 Pfam PF00795 Carbon-nitrogen hydrolase 24 281 7.0E-17 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS16125 96ddab9664f135069bb96a1220972fba 687 SUPERFAMILY SSF56317 13 297 1.18E-46 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS16125 96ddab9664f135069bb96a1220972fba 687 TIGRFAM TIGR00552 nadE: NAD+ synthetase 355 525 3.4E-20 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CVS48_RS12635 984658c66a7ab3b8bf2fa2d4f2b255d4 232 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 232 3.5E-105 T 29-03-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE CVS48_RS12635 984658c66a7ab3b8bf2fa2d4f2b255d4 232 Gene3D G3DSA:3.40.50.300 1 225 1.1E-56 T 29-03-2018 CVS48_RS12635 984658c66a7ab3b8bf2fa2d4f2b255d4 232 Pfam PF00005 ABC transporter 17 161 1.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS12635 984658c66a7ab3b8bf2fa2d4f2b255d4 232 SUPERFAMILY SSF52540 2 221 4.33E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS12635 984658c66a7ab3b8bf2fa2d4f2b255d4 232 SMART SM00382 26 211 2.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05855 33c264f9ed930e21aec4656dac54276f 385 Gene3D G3DSA:3.30.9.10 192 323 8.5E-23 T 29-03-2018 CVS48_RS05855 33c264f9ed930e21aec4656dac54276f 385 Gene3D G3DSA:3.50.50.60 2 111 5.5E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05855 33c264f9ed930e21aec4656dac54276f 385 Gene3D G3DSA:3.30.9.10 112 191 4.9E-6 T 29-03-2018 CVS48_RS05855 33c264f9ed930e21aec4656dac54276f 385 SUPERFAMILY SSF54373 241 323 1.57E-10 T 29-03-2018 CVS48_RS05855 33c264f9ed930e21aec4656dac54276f 385 SUPERFAMILY SSF51905 18 241 3.21E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05855 33c264f9ed930e21aec4656dac54276f 385 SUPERFAMILY SSF51905 325 381 3.21E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05855 33c264f9ed930e21aec4656dac54276f 385 Pfam PF01266 FAD dependent oxidoreductase 19 359 1.0E-46 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS13150 10246f183c4f2af0f29d2609b62385cc 538 Gene3D G3DSA:3.30.750.24 392 531 8.2E-24 T 29-03-2018 IPR002645 STAS domain CVS48_RS13150 10246f183c4f2af0f29d2609b62385cc 538 Pfam PF00916 Sulfate permease family 1 357 2.2E-76 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CVS48_RS13150 10246f183c4f2af0f29d2609b62385cc 538 Pfam PF01740 STAS domain 414 522 2.1E-12 T 29-03-2018 IPR002645 STAS domain CVS48_RS13150 10246f183c4f2af0f29d2609b62385cc 538 SUPERFAMILY SSF52091 413 527 6.28E-14 T 29-03-2018 IPR002645 STAS domain CVS48_RS27400 b24ba81b57a50dc4d39259a48d56cae5 342 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 154 162 - T 29-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 CVS48_RS27400 b24ba81b57a50dc4d39259a48d56cae5 342 Pfam PF13531 Bacterial extracellular solute-binding protein 37 289 6.1E-46 T 29-03-2018 CVS48_RS27400 b24ba81b57a50dc4d39259a48d56cae5 342 Gene3D G3DSA:3.40.190.10 135 253 1.3E-27 T 29-03-2018 CVS48_RS27400 b24ba81b57a50dc4d39259a48d56cae5 342 Gene3D G3DSA:3.40.190.10 254 339 1.6E-28 T 29-03-2018 CVS48_RS27400 b24ba81b57a50dc4d39259a48d56cae5 342 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 27 336 4.3E-148 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CVS48_RS27400 b24ba81b57a50dc4d39259a48d56cae5 342 Gene3D G3DSA:3.40.190.10 29 134 1.3E-23 T 29-03-2018 CVS48_RS27400 b24ba81b57a50dc4d39259a48d56cae5 342 SUPERFAMILY SSF53850 29 337 2.98E-93 T 29-03-2018 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 SUPERFAMILY SSF47781 66 133 6.67E-20 T 29-03-2018 IPR010994 RuvA domain 2-like CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 SUPERFAMILY SSF50249 1 63 8.0E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 SMART SM00278 73 92 3.5 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 SMART SM00278 108 127 0.0015 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 SUPERFAMILY SSF46929 145 189 5.62E-8 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 Pfam PF14520 Helix-hairpin-helix domain 72 129 8.6E-18 T 29-03-2018 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 188 8.7E-51 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 Pfam PF01330 RuvA N terminal domain 1 62 2.6E-20 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 Gene3D G3DSA:2.40.50.140 1 58 1.9E-23 T 29-03-2018 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 Pfam PF07499 RuvA, C-terminal domain 146 188 1.1E-11 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 189 30.046 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 Gene3D G3DSA:1.10.8.10 142 190 1.5E-9 T 29-03-2018 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 Gene3D G3DSA:1.10.150.280 59 81 0.43 T 29-03-2018 CVS48_RS01425 ec270a28dd96f0247e7600ab033e3c75 190 Gene3D G3DSA:1.10.150.20 82 141 2.7E-16 T 29-03-2018 CVS48_RS16075 e8fba4f8f03066d539a28b186b1c8d2b 347 Gene3D G3DSA:3.40.50.970 10 220 1.3E-64 T 29-03-2018 CVS48_RS16075 e8fba4f8f03066d539a28b186b1c8d2b 347 Gene3D G3DSA:3.40.50.920 221 346 1.9E-30 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS16075 e8fba4f8f03066d539a28b186b1c8d2b 347 SUPERFAMILY SSF52922 215 345 7.46E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS16075 e8fba4f8f03066d539a28b186b1c8d2b 347 SUPERFAMILY SSF52518 12 229 3.85E-67 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS16075 e8fba4f8f03066d539a28b186b1c8d2b 347 Pfam PF02780 Transketolase, C-terminal domain 222 337 9.3E-37 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CVS48_RS16075 e8fba4f8f03066d539a28b186b1c8d2b 347 Pfam PF02779 Transketolase, pyrimidine binding domain 13 188 4.8E-45 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS16075 e8fba4f8f03066d539a28b186b1c8d2b 347 SMART SM00861 14 189 1.0E-66 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS22630 c55458539aba90fd5c7ddeefecb2cac4 287 Pfam PF00494 Squalene/phytoene synthase 13 264 4.2E-80 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CVS48_RS22630 c55458539aba90fd5c7ddeefecb2cac4 287 Gene3D G3DSA:1.10.600.10 2 278 5.6E-91 T 29-03-2018 IPR008949 Isoprenoid synthase domain CVS48_RS22630 c55458539aba90fd5c7ddeefecb2cac4 287 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 10 275 4.0E-119 T 29-03-2018 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 CVS48_RS22630 c55458539aba90fd5c7ddeefecb2cac4 287 SUPERFAMILY SSF48576 3 276 1.18E-91 T 29-03-2018 IPR008949 Isoprenoid synthase domain CVS48_RS22630 c55458539aba90fd5c7ddeefecb2cac4 287 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 152 177 - T 29-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CVS48_RS10215 bea8b05e1e94062b93c4091dca3cb65c 301 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 285 2.1E-34 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS10215 bea8b05e1e94062b93c4091dca3cb65c 301 Gene3D G3DSA:1.10.3470.10 1 300 1.6E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS16150 d2b6b0da3e280d4bd888410c76a8ee53 252 Pfam PF01203 Type II secretion system (T2SS), protein N 44 244 1.9E-17 T 29-03-2018 IPR022792 Type II secretion system, protein N CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 396 546 1.5E-25 T 29-03-2018 IPR006512 YidE/YbjL duplication CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 SUPERFAMILY SSF116726 223 279 1.44E-8 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 Gene3D G3DSA:3.30.70.1450 292 383 7.0E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 SUPERFAMILY SSF116726 290 378 1.12E-8 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 Pfam PF02080 TrkA-C domain 304 373 6.8E-7 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 Pfam PF02080 TrkA-C domain 225 278 1.8E-8 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 Pfam PF06826 Predicted Permease Membrane Region 392 560 9.6E-41 T 29-03-2018 IPR006512 YidE/YbjL duplication CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 Pfam PF06826 Predicted Permease Membrane Region 15 175 2.9E-37 T 29-03-2018 IPR006512 YidE/YbjL duplication CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 Gene3D G3DSA:3.30.70.1450 221 291 8.4E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS27425 3c65e40ff5c509926b66043b8d1b5f71 563 TIGRFAM TIGR03802 Asp_Ala_antiprt: aspartate-alanine antiporter 2 562 5.4E-197 T 29-03-2018 IPR022457 Aspartate-alanine antiporter GO:0005215|GO:0016020 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Pfam PF13181 Tetratricopeptide repeat 71 103 0.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Gene3D G3DSA:1.25.40.120 223 306 1.7E-7 T 29-03-2018 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 SUPERFAMILY SSF53756 333 590 3.77E-24 T 29-03-2018 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Gene3D G3DSA:1.25.40.120 3 81 4.6E-10 T 29-03-2018 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Pfam PF13432 Tetratricopeptide repeat 7 67 0.0035 T 29-03-2018 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Pfam PF13432 Tetratricopeptide repeat 253 298 1.8E-7 T 29-03-2018 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 SUPERFAMILY SSF48452 97 305 7.21E-32 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Pfam PF00515 Tetratricopeptide repeat 139 172 1.9E-8 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Gene3D G3DSA:1.25.40.10 116 146 7.2E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Gene3D G3DSA:1.25.40.10 147 181 1.8E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Gene3D G3DSA:1.25.40.10 82 115 9.2E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 SMART SM00028 173 206 0.088 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 SMART SM00028 71 104 0.18 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 SMART SM00028 139 172 8.8E-7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 SMART SM00028 3 36 30.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 SMART SM00028 105 138 0.013 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 SUPERFAMILY SSF48452 8 132 1.14E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Gene3D G3DSA:3.40.50.2000 428 596 7.4E-38 T 29-03-2018 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Pfam PF13374 Tetratricopeptide repeat 173 202 0.0043 T 29-03-2018 CVS48_RS11855 a05399c398c39e0fc28dd0cded3d2e94 598 Gene3D G3DSA:1.10.150.200 182 221 1.7E-7 T 29-03-2018 CVS48_RS04245 84dddefb36a731b65b2cd65d3f61f8dc 343 Pfam PF00591 Glycosyl transferase family, a/b domain 77 327 5.1E-91 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CVS48_RS04245 84dddefb36a731b65b2cd65d3f61f8dc 343 SUPERFAMILY SSF52418 77 340 4.06E-94 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CVS48_RS04245 84dddefb36a731b65b2cd65d3f61f8dc 343 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 337 36.591 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CVS48_RS04245 84dddefb36a731b65b2cd65d3f61f8dc 343 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 10 336 8.8E-124 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CVS48_RS04245 84dddefb36a731b65b2cd65d3f61f8dc 343 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 68 1.7E-10 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CVS48_RS04245 84dddefb36a731b65b2cd65d3f61f8dc 343 Gene3D G3DSA:1.20.970.10 1 72 1.3E-15 T 29-03-2018 CVS48_RS04245 84dddefb36a731b65b2cd65d3f61f8dc 343 Gene3D G3DSA:3.40.1030.10 73 343 6.0E-102 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CVS48_RS04245 84dddefb36a731b65b2cd65d3f61f8dc 343 SUPERFAMILY SSF47648 5 71 6.41E-16 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CVS48_RS02100 e49af41990e2721052e99bc577d299bf 161 Pfam PF04965 Gene 25-like lysozyme 30 130 1.4E-21 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD CVS48_RS02100 e49af41990e2721052e99bc577d299bf 161 SUPERFAMILY SSF160719 30 143 2.88E-11 T 29-03-2018 CVS48_RS02100 e49af41990e2721052e99bc577d299bf 161 Gene3D G3DSA:3.10.450.40 5 145 9.4E-26 T 29-03-2018 CVS48_RS02100 e49af41990e2721052e99bc577d299bf 161 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 5 150 1.3E-37 T 29-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein CVS48_RS03260 35942bb7b6c6e9b481826e42a0a7c4d1 277 Pfam PF00149 Calcineurin-like phosphoesterase 4 140 1.6E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS03260 35942bb7b6c6e9b481826e42a0a7c4d1 277 SUPERFAMILY SSF56300 2 258 2.24E-50 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS03260 35942bb7b6c6e9b481826e42a0a7c4d1 277 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 5 266 1.3E-71 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CVS48_RS03260 35942bb7b6c6e9b481826e42a0a7c4d1 277 Gene3D G3DSA:3.60.21.10 2 275 5.5E-41 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS03260 35942bb7b6c6e9b481826e42a0a7c4d1 277 PIRSF PIRSF000903 3 274 1.3E-100 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CVS48_RS03260 35942bb7b6c6e9b481826e42a0a7c4d1 277 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 3 271 43.231 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 16 454 6.2E-120 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 Pfam PF08328 Adenylosuccinate lyase C-terminal 334 448 5.5E-49 T 29-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 Gene3D G3DSA:1.20.200.10 121 393 6.9E-79 T 29-03-2018 CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 SUPERFAMILY SSF48557 7 450 2.98E-99 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 PRINTS PR00149 Fumarate lyase superfamily signature 254 281 1.1E-15 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 PRINTS PR00149 Fumarate lyase superfamily signature 120 138 1.1E-15 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 PRINTS PR00149 Fumarate lyase superfamily signature 297 313 1.1E-15 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 PRINTS PR00149 Fumarate lyase superfamily signature 166 184 1.1E-15 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 ProSitePatterns PS00163 Fumarate lyases signature. 297 306 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 Pfam PF00206 Lyase 18 315 7.2E-57 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 Gene3D G3DSA:1.10.275.10 4 120 1.9E-39 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CVS48_RS26590 9eb0f7c5f17806af5fc3270b9f6336ce 458 Gene3D G3DSA:1.10.40.30 394 448 6.7E-30 T 29-03-2018 CVS48_RS04695 a9752bd3b8bb30b3cfd684e000f732e0 403 Gene3D G3DSA:2.160.20.10 39 388 7.0E-60 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS04695 a9752bd3b8bb30b3cfd684e000f732e0 403 Pfam PF00544 Pectate lyase 100 272 1.2E-22 T 29-03-2018 IPR002022 Pectate lyase CVS48_RS04695 a9752bd3b8bb30b3cfd684e000f732e0 403 PRINTS PR00807 Pollen allergen Amb family signature 233 252 3.4E-11 T 29-03-2018 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 CVS48_RS04695 a9752bd3b8bb30b3cfd684e000f732e0 403 PRINTS PR00807 Pollen allergen Amb family signature 45 62 3.4E-11 T 29-03-2018 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 CVS48_RS04695 a9752bd3b8bb30b3cfd684e000f732e0 403 PRINTS PR00807 Pollen allergen Amb family signature 255 274 3.4E-11 T 29-03-2018 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 CVS48_RS04695 a9752bd3b8bb30b3cfd684e000f732e0 403 PRINTS PR00807 Pollen allergen Amb family signature 102 118 3.4E-11 T 29-03-2018 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 CVS48_RS04695 a9752bd3b8bb30b3cfd684e000f732e0 403 SUPERFAMILY SSF51126 45 283 8.9E-61 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS04695 a9752bd3b8bb30b3cfd684e000f732e0 403 SUPERFAMILY SSF51126 333 384 8.9E-61 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS04695 a9752bd3b8bb30b3cfd684e000f732e0 403 SMART SM00656 94 278 8.3E-20 T 29-03-2018 IPR002022 Pectate lyase CVS48_RS17565 f80235397966548189883aea3e17a056 490 SUPERFAMILY SSF47384 256 335 1.1E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS17565 f80235397966548189883aea3e17a056 490 Gene3D G3DSA:3.30.450.20 34 162 4.8E-5 T 29-03-2018 CVS48_RS17565 f80235397966548189883aea3e17a056 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 432 2.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS17565 f80235397966548189883aea3e17a056 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 468 2.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS17565 f80235397966548189883aea3e17a056 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 487 2.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS17565 f80235397966548189883aea3e17a056 490 Gene3D G3DSA:3.30.565.10 330 489 2.9E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS17565 f80235397966548189883aea3e17a056 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 487 9.4E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS17565 f80235397966548189883aea3e17a056 490 SMART SM00388 267 335 7.1E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS17565 f80235397966548189883aea3e17a056 490 Pfam PF00512 His Kinase A (phospho-acceptor) domain 268 335 1.0E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS17565 f80235397966548189883aea3e17a056 490 SMART SM00387 381 490 5.7E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS17565 f80235397966548189883aea3e17a056 490 Gene3D G3DSA:1.10.287.130 258 329 7.7E-15 T 29-03-2018 CVS48_RS17565 f80235397966548189883aea3e17a056 490 SUPERFAMILY SSF55874 325 486 3.67E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS06500 2fe64f9509d0029d81a43d6b66d2c55a 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.56 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06500 2fe64f9509d0029d81a43d6b66d2c55a 179 SUPERFAMILY SSF55282 3 179 2.12E-76 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06500 2fe64f9509d0029d81a43d6b66d2c55a 179 PIRSF PIRSF002161 1 179 2.9E-63 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06500 2fe64f9509d0029d81a43d6b66d2c55a 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06500 2fe64f9509d0029d81a43d6b66d2c55a 179 Gene3D G3DSA:3.30.1440.10 1 179 1.2E-75 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06500 2fe64f9509d0029d81a43d6b66d2c55a 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 3.7E-40 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06500 2fe64f9509d0029d81a43d6b66d2c55a 179 Pfam PF00281 Ribosomal protein L5 24 80 2.5E-26 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 190 3.3E-8 T 29-03-2018 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 298 3.3E-8 T 29-03-2018 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Gene3D G3DSA:2.40.30.110 906 1006 3.6E-21 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Gene3D G3DSA:3.50.50.60 334 557 7.0E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Gene3D G3DSA:3.30.1360.120 609 744 1.3E-30 T 29-03-2018 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Gene3D G3DSA:3.50.50.60 130 333 2.1E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 TIGRFAM TIGR01372 soxA: sarcosine oxidase, alpha subunit family 3 1005 0.0 T 29-03-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 170 430 3.2E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 PIRSF PIRSF037980 1 1005 0.0 T 29-03-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 SUPERFAMILY SSF103025 608 901 7.53E-93 T 29-03-2018 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 SUPERFAMILY SSF101790 899 1004 1.42E-17 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 192 2.4E-10 T 29-03-2018 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 563 578 2.4E-10 T 29-03-2018 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 292 2.4E-10 T 29-03-2018 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 SUPERFAMILY SSF51905 159 479 1.92E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Pfam PF01571 Aminomethyltransferase folate-binding domain 615 882 1.5E-75 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Gene3D G3DSA:3.30.1360.120 745 860 2.0E-20 T 29-03-2018 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 101 1.7E-21 T 29-03-2018 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 890 990 7.9E-15 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CVS48_RS01110 d95b32f0b7302d143740db0f25c8f4f5 1006 Gene3D G3DSA:4.10.1250.10 862 901 5.6E-6 T 29-03-2018 CVS48_RS20205 0792910f1104912a29585cd73cc2f98a 234 PIRSF PIRSF037290 1 231 3.2E-78 T 29-03-2018 IPR017166 Uncharacterised conserved protein UCP037290 CVS48_RS20205 0792910f1104912a29585cd73cc2f98a 234 SUPERFAMILY SSF52540 44 157 4.99E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20205 0792910f1104912a29585cd73cc2f98a 234 Gene3D G3DSA:3.40.50.300 43 158 2.1E-28 T 29-03-2018 CVS48_RS01630 dcb1cf02b2214d384f6d9bd5bce5a1ee 311 SUPERFAMILY SSF53448 6 251 3.94E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS01630 dcb1cf02b2214d384f6d9bd5bce5a1ee 311 Gene3D G3DSA:3.90.550.10 6 224 9.7E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS01630 dcb1cf02b2214d384f6d9bd5bce5a1ee 311 Pfam PF00535 Glycosyl transferase family 2 9 116 9.5E-27 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 496 3.0E-41 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 248 266 3.0E-41 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 451 469 3.0E-41 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 139 158 3.0E-41 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 469 483 3.0E-41 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 325 346 3.0E-41 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 Pfam PF00342 Phosphoglucose isomerase 64 528 1.1E-135 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 Gene3D G3DSA:1.10.1390.10 499 546 1.1E-15 T 29-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 SUPERFAMILY SSF53697 22 538 1.58E-145 T 29-03-2018 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 Gene3D G3DSA:3.40.50.10490 7 132 4.7E-13 T 29-03-2018 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 Gene3D G3DSA:3.40.50.10490 246 498 7.3E-88 T 29-03-2018 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 483 500 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 Gene3D G3DSA:3.40.50.10490 133 245 1.2E-32 T 29-03-2018 CVS48_RS23730 d72feaf08f9f6632ef3010c88ffa7d68 555 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 45 510 32.384 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 SUPERFAMILY SSF51735 6 246 4.53E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 Gene3D G3DSA:3.40.50.720 2 247 5.7E-60 T 29-03-2018 CVS48_RS16440 93e0330f4bdba96613122d517ee1d5e4 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 6.1E-49 T 29-03-2018 CVS48_RS02955 44e62001942c0e907527323b8efbca7c 187 Gene3D G3DSA:3.40.50.850 1 187 7.6E-36 T 29-03-2018 CVS48_RS02955 44e62001942c0e907527323b8efbca7c 187 Pfam PF00857 Isochorismatase family 4 149 3.9E-27 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS02955 44e62001942c0e907527323b8efbca7c 187 SUPERFAMILY SSF52499 2 186 4.71E-34 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS26485 d674e2caab3a9cb6ef5920eec2e6fa0f 407 Pfam PF04143 Sulphur transport 62 385 6.1E-71 T 29-03-2018 IPR007272 Sulphur transport domain CVS48_RS06490 61c007f9e6635b53c4a1604617a19106 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.068 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CVS48_RS06490 61c007f9e6635b53c4a1604617a19106 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 9.4E-57 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CVS48_RS06490 61c007f9e6635b53c4a1604617a19106 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06490 61c007f9e6635b53c4a1604617a19106 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.2E-53 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CVS48_RS06490 61c007f9e6635b53c4a1604617a19106 122 SUPERFAMILY SSF50193 1 122 1.28E-50 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CVS48_RS06490 61c007f9e6635b53c4a1604617a19106 122 SMART SM01374 1 122 9.5E-83 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CVS48_RS06490 61c007f9e6635b53c4a1604617a19106 122 Gene3D G3DSA:2.40.150.20 1 122 1.6E-51 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CVS48_RS20985 6de5c736fc7ed9f0feeef972a2e800f0 112 PRINTS PR00355 Adrenodoxin signature 83 91 4.2E-8 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CVS48_RS20985 6de5c736fc7ed9f0feeef972a2e800f0 112 PRINTS PR00355 Adrenodoxin signature 60 74 4.2E-8 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CVS48_RS20985 6de5c736fc7ed9f0feeef972a2e800f0 112 PRINTS PR00355 Adrenodoxin signature 42 52 4.2E-8 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CVS48_RS20985 6de5c736fc7ed9f0feeef972a2e800f0 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 1.0E-53 T 29-03-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 CVS48_RS20985 6de5c736fc7ed9f0feeef972a2e800f0 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 29-03-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CVS48_RS20985 6de5c736fc7ed9f0feeef972a2e800f0 112 SUPERFAMILY SSF54292 5 108 4.16E-28 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS20985 6de5c736fc7ed9f0feeef972a2e800f0 112 Gene3D G3DSA:3.10.20.30 3 112 1.4E-28 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS20985 6de5c736fc7ed9f0feeef972a2e800f0 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 18 91 6.1E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS10635 cbd022841990e6d13306345173dc6c9f 497 Gene3D G3DSA:3.40.605.10 1 262 5.8E-86 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS10635 cbd022841990e6d13306345173dc6c9f 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS10635 cbd022841990e6d13306345173dc6c9f 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 481 1.3E-211 T 29-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CVS48_RS10635 cbd022841990e6d13306345173dc6c9f 497 SUPERFAMILY SSF53720 3 482 9.29E-152 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS10635 cbd022841990e6d13306345173dc6c9f 497 Pfam PF00171 Aldehyde dehydrogenase family 19 477 3.6E-142 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS10635 cbd022841990e6d13306345173dc6c9f 497 Gene3D G3DSA:3.40.309.10 263 460 1.9E-64 T 29-03-2018 CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 Gene3D G3DSA:3.30.365.10 443 579 4.1E-26 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 166 674 4.8E-121 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 SUPERFAMILY SSF54665 9 138 9.42E-29 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 SUPERFAMILY SSF56003 161 736 5.76E-162 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 37 137 3.2E-19 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 SMART SM01008 32 138 2.0E-23 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 Gene3D G3DSA:3.90.1170.50 2 138 6.3E-25 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 Gene3D G3DSA:3.30.365.10 265 422 1.1E-30 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 Gene3D G3DSA:3.30.365.10 580 736 2.5E-48 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS25075 98664384e6f522101ef6ef21a2f953f3 738 Gene3D G3DSA:3.30.365.10 166 264 9.3E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS28800 03bae7c7c0c432de7a34f5ea34ea5414 486 Pfam PF02321 Outer membrane efflux protein 293 473 1.3E-22 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS28800 03bae7c7c0c432de7a34f5ea34ea5414 486 Pfam PF02321 Outer membrane efflux protein 75 265 1.5E-18 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS28800 03bae7c7c0c432de7a34f5ea34ea5414 486 Gene3D G3DSA:1.20.1600.10 20 481 2.4E-76 T 29-03-2018 CVS48_RS28800 03bae7c7c0c432de7a34f5ea34ea5414 486 SUPERFAMILY SSF56954 5 34 3.01E-86 T 29-03-2018 CVS48_RS28800 03bae7c7c0c432de7a34f5ea34ea5414 486 SUPERFAMILY SSF56954 66 474 3.01E-86 T 29-03-2018 CVS48_RS28800 03bae7c7c0c432de7a34f5ea34ea5414 486 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 474 9.6E-101 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS27740 65b7c535d1466225f1822d37faf65d25 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 5.3E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS27740 65b7c535d1466225f1822d37faf65d25 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 5.3E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS27740 65b7c535d1466225f1822d37faf65d25 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 5.3E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS27740 65b7c535d1466225f1822d37faf65d25 304 SMART SM01130 5 293 7.8E-82 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS27740 65b7c535d1466225f1822d37faf65d25 304 Pfam PF00701 Dihydrodipicolinate synthetase family 7 290 4.1E-53 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS27740 65b7c535d1466225f1822d37faf65d25 304 Gene3D G3DSA:3.20.20.70 1 303 1.0E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS27740 65b7c535d1466225f1822d37faf65d25 304 PIRSF PIRSF001365 1 302 2.0E-77 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS27740 65b7c535d1466225f1822d37faf65d25 304 SUPERFAMILY SSF51569 4 291 1.78E-80 T 29-03-2018 CVS48_RS03095 fa4fd7fdaccdd3a4ab362a7e32762bee 399 SUPERFAMILY SSF103473 9 395 7.59E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS03095 fa4fd7fdaccdd3a4ab362a7e32762bee 399 Gene3D G3DSA:1.20.1250.20 6 192 1.6E-28 T 29-03-2018 CVS48_RS03095 fa4fd7fdaccdd3a4ab362a7e32762bee 399 Gene3D G3DSA:1.20.1250.20 201 395 4.5E-25 T 29-03-2018 CVS48_RS03095 fa4fd7fdaccdd3a4ab362a7e32762bee 399 Pfam PF07690 Major Facilitator Superfamily 14 344 1.5E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS04790 6e7120b6d7908bb72f836f56523f5d97 409 Gene3D G3DSA:3.10.28.20 289 383 2.1E-16 T 29-03-2018 CVS48_RS04790 6e7120b6d7908bb72f836f56523f5d97 409 Pfam PF03069 Acetamidase/Formamidase family 7 383 2.2E-175 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 CVS48_RS04790 6e7120b6d7908bb72f836f56523f5d97 409 Gene3D G3DSA:2.60.120.580 150 281 4.3E-32 T 29-03-2018 CVS48_RS04790 6e7120b6d7908bb72f836f56523f5d97 409 Gene3D G3DSA:2.60.120.580 2 149 6.9E-34 T 29-03-2018 CVS48_RS04790 6e7120b6d7908bb72f836f56523f5d97 409 SUPERFAMILY SSF141130 213 383 1.02E-77 T 29-03-2018 CVS48_RS04790 6e7120b6d7908bb72f836f56523f5d97 409 SUPERFAMILY SSF141130 16 164 1.02E-77 T 29-03-2018 CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 SUPERFAMILY SSF46785 1 82 2.59E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 Gene3D G3DSA:3.40.190.10 178 268 5.1E-27 T 29-03-2018 CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 Gene3D G3DSA:3.40.190.10 88 177 5.6E-24 T 29-03-2018 CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 SUPERFAMILY SSF53850 89 299 9.12E-39 T 29-03-2018 CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 Gene3D G3DSA:1.10.10.10 1 82 1.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 Pfam PF03466 LysR substrate binding domain 87 292 7.5E-42 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23450 ee0ef79598315e4274dcdd811ad209d5 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.0E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20645 a88907fdc382bc1e4c64229ff55e4b4e 228 SUPERFAMILY SSF48008 78 209 1.26E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS20645 a88907fdc382bc1e4c64229ff55e4b4e 228 Gene3D G3DSA:1.20.120.530 75 217 4.9E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS20645 a88907fdc382bc1e4c64229ff55e4b4e 228 SUPERFAMILY SSF46785 9 89 1.32E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20645 a88907fdc382bc1e4c64229ff55e4b4e 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 72 1.5E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS20645 a88907fdc382bc1e4c64229ff55e4b4e 228 Gene3D G3DSA:1.10.10.10 2 74 3.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20645 a88907fdc382bc1e4c64229ff55e4b4e 228 SMART SM00895 82 205 1.8E-17 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS20645 a88907fdc382bc1e4c64229ff55e4b4e 228 SMART SM00345 14 72 7.1E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS20645 a88907fdc382bc1e4c64229ff55e4b4e 228 Pfam PF07729 FCD domain 82 204 3.4E-22 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 SMART SM00448 923 1034 1.0E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 SMART SM00388 678 744 5.6E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 Gene3D G3DSA:3.30.565.10 739 900 1.5E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 SUPERFAMILY SSF55874 734 897 2.49E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 Gene3D G3DSA:3.40.50.2300 919 1129 1.4E-30 T 29-03-2018 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 SUPERFAMILY SSF52172 921 1046 9.11E-31 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 Gene3D G3DSA:1.10.287.130 682 738 8.4E-19 T 29-03-2018 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 SMART SM00387 790 901 2.0E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 791 898 3.4E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 SUPERFAMILY SSF47384 664 745 1.41E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 Pfam PF00072 Response regulator receiver domain 925 1032 8.1E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 Gene3D G3DSA:3.30.450.20 349 681 9.0E-5 T 29-03-2018 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 Pfam PF00512 His Kinase A (phospho-acceptor) domain 678 744 7.1E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 PRINTS PR00344 Bacterial sensor protein C-terminal signature 826 840 7.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 PRINTS PR00344 Bacterial sensor protein C-terminal signature 885 898 7.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS04820 ec5a0878c68665822e36c77a0aeeaa9e 1130 PRINTS PR00344 Bacterial sensor protein C-terminal signature 861 879 7.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 SUPERFAMILY SSF82693 135 180 1.65E-19 T 29-03-2018 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 SUPERFAMILY SSF82693 266 322 1.65E-19 T 29-03-2018 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 Pfam PF00873 AcrB/AcrD/AcrF family 1 1015 3.8E-294 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 SUPERFAMILY SSF82693 38 132 9.94E-22 T 29-03-2018 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 Gene3D G3DSA:1.20.1640.10 815 1018 9.7E-34 T 29-03-2018 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 Gene3D G3DSA:1.20.1640.10 265 490 1.8E-41 T 29-03-2018 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 SUPERFAMILY SSF82866 800 1019 1.16E-40 T 29-03-2018 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 Gene3D G3DSA:3.30.70.1430 38 140 3.4E-25 T 29-03-2018 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 Gene3D G3DSA:3.30.70.1430 562 652 2.9E-6 T 29-03-2018 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 SUPERFAMILY SSF82714 710 794 3.27E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 SUPERFAMILY SSF82693 560 650 5.49E-11 T 29-03-2018 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 SUPERFAMILY SSF82714 181 264 3.66E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.3E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 PRINTS PR00702 Acriflavin resistance protein family signature 611 625 2.3E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 2.3E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.3E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 PRINTS PR00702 Acriflavin resistance protein family signature 547 564 2.3E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 2.3E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 2.3E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 2.3E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 2.3E-68 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 Gene3D G3DSA:3.30.2090.10 707 796 3.5E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 Gene3D G3DSA:3.30.2090.10 179 264 4.5E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS17665 10366a6b648ebf687bc81724c2056ada 1041 SUPERFAMILY SSF82866 288 489 9.02E-42 T 29-03-2018 CVS48_RS05425 1601ca8b6d53a8c7072bd172123f1eb8 431 Gene3D G3DSA:3.40.190.10 145 427 2.5E-52 T 29-03-2018 CVS48_RS05425 1601ca8b6d53a8c7072bd172123f1eb8 431 Pfam PF13416 Bacterial extracellular solute-binding protein 49 366 3.2E-50 T 29-03-2018 CVS48_RS05425 1601ca8b6d53a8c7072bd172123f1eb8 431 SUPERFAMILY SSF53850 30 424 2.32E-79 T 29-03-2018 CVS48_RS09940 93b229f59db066882edc5889019b0266 408 Pfam PF07804 HipA-like C-terminal domain 173 385 5.8E-41 T 29-03-2018 IPR012893 HipA-like, C-terminal CVS48_RS09940 93b229f59db066882edc5889019b0266 408 Pfam PF13657 HipA N-terminal domain 18 92 1.1E-5 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CVS48_RS11205 f8c3ebb1568ce185331f4e3572f84847 321 Gene3D G3DSA:3.40.190.10 120 231 6.7E-13 T 29-03-2018 CVS48_RS11205 f8c3ebb1568ce185331f4e3572f84847 321 PIRSF PIRSF017082 1 320 2.1E-75 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11205 f8c3ebb1568ce185331f4e3572f84847 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 317 2.1E-79 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11205 f8c3ebb1568ce185331f4e3572f84847 321 SUPERFAMILY SSF53850 46 285 3.09E-14 T 29-03-2018 CVS48_RS23565 47825d2dd2c7e3596ec8c8cd3222f239 466 SUPERFAMILY SSF52540 139 366 1.57E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23565 47825d2dd2c7e3596ec8c8cd3222f239 466 SMART SM00382 159 302 7.4E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS23565 47825d2dd2c7e3596ec8c8cd3222f239 466 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 225 240 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CVS48_RS23565 47825d2dd2c7e3596ec8c8cd3222f239 466 Gene3D G3DSA:1.10.10.60 400 448 4.0E-9 T 29-03-2018 CVS48_RS23565 47825d2dd2c7e3596ec8c8cd3222f239 466 Gene3D G3DSA:3.40.50.300 134 311 9.8E-24 T 29-03-2018 CVS48_RS23565 47825d2dd2c7e3596ec8c8cd3222f239 466 Pfam PF00158 Sigma-54 interaction domain 140 305 2.8E-62 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CVS48_RS23565 47825d2dd2c7e3596ec8c8cd3222f239 466 Pfam PF02954 Bacterial regulatory protein, Fis family 410 449 6.2E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS23565 47825d2dd2c7e3596ec8c8cd3222f239 466 SUPERFAMILY SSF46689 409 451 1.02E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS23565 47825d2dd2c7e3596ec8c8cd3222f239 466 Gene3D G3DSA:1.10.8.60 316 380 3.3E-6 T 29-03-2018 CVS48_RS26040 2c9551d586e1262a92b9501e58773398 315 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14 189 5.3E-47 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS26040 2c9551d586e1262a92b9501e58773398 315 Gene3D G3DSA:3.40.50.720 1 190 1.5E-44 T 29-03-2018 CVS48_RS26040 2c9551d586e1262a92b9501e58773398 315 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 193 255 1.8E-12 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS26040 2c9551d586e1262a92b9501e58773398 315 Gene3D G3DSA:1.10.1040.10 193 295 4.0E-17 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS26040 2c9551d586e1262a92b9501e58773398 315 SUPERFAMILY SSF51735 10 190 1.09E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS26040 2c9551d586e1262a92b9501e58773398 315 SUPERFAMILY SSF48179 193 285 3.91E-13 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS26040 2c9551d586e1262a92b9501e58773398 315 PIRSF PIRSF000105 6 268 8.0E-67 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 Gene3D G3DSA:1.10.510.10 375 570 4.5E-39 T 29-03-2018 CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 Gene3D G3DSA:3.30.200.20 286 374 1.3E-10 T 29-03-2018 CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 SMART SM00332 12 256 4.1E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 Pfam PF13672 Protein phosphatase 2C 36 222 1.8E-15 T 29-03-2018 CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 Pfam PF00069 Protein kinase domain 303 555 3.1E-34 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 SUPERFAMILY SSF56112 271 557 5.53E-55 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 SUPERFAMILY SSF81606 22 259 1.31E-46 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 410 422 - T 29-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 SMART SM00331 40 258 3.4E-15 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CVS48_RS21385 acac4d4859ac32e4a4a8747f31a6ba3b 594 Gene3D G3DSA:3.60.40.10 13 276 4.2E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CVS48_RS04220 45f0f8ed17be46aecb820fc52d9b8594 124 Hamap MF_00791 Protein ApaG [apaG]. 1 124 32.575 T 29-03-2018 IPR023065 Uncharacterised protein family ApaG CVS48_RS04220 45f0f8ed17be46aecb820fc52d9b8594 124 Pfam PF04379 ApaG domain 16 101 7.7E-37 T 29-03-2018 IPR007474 ApaG domain CVS48_RS04220 45f0f8ed17be46aecb820fc52d9b8594 124 SUPERFAMILY SSF110069 5 124 1.83E-48 T 29-03-2018 IPR007474 ApaG domain CVS48_RS04220 45f0f8ed17be46aecb820fc52d9b8594 124 Gene3D G3DSA:2.60.40.1470 3 124 3.0E-45 T 29-03-2018 IPR007474 ApaG domain CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 SMART SM00388 178 243 1.1E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 Pfam PF00072 Response regulator receiver domain 429 537 2.6E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 Pfam PF00512 His Kinase A (phospho-acceptor) domain 178 243 1.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 SMART SM00448 427 537 3.9E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 SUPERFAMILY SSF55874 233 397 1.07E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 Gene3D G3DSA:1.10.287.130 183 239 4.2E-11 T 29-03-2018 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 SUPERFAMILY SSF52172 425 562 1.71E-15 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 Gene3D G3DSA:3.30.565.10 247 406 1.9E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 Gene3D G3DSA:3.40.50.2300 421 585 5.6E-16 T 29-03-2018 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 SMART SM00387 288 399 9.3E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 Gene3D G3DSA:3.30.450.20 29 182 4.1E-18 T 29-03-2018 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 377 3.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 338 3.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 396 3.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 SUPERFAMILY SSF55785 41 155 1.86E-8 T 29-03-2018 IPR000014 PAS domain CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 Pfam PF12860 PAS fold 35 151 1.6E-37 T 29-03-2018 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 SUPERFAMILY SSF47384 163 243 2.55E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS13680 7c3b3a2a7944718ac65ba8c760ac51d0 590 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 397 1.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16015 6131a04eaf47e44b6b31527e491254fd 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS16015 6131a04eaf47e44b6b31527e491254fd 478 Gene3D G3DSA:3.40.309.10 264 460 1.3E-63 T 29-03-2018 CVS48_RS16015 6131a04eaf47e44b6b31527e491254fd 478 Gene3D G3DSA:3.40.605.10 1 263 1.0E-98 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS16015 6131a04eaf47e44b6b31527e491254fd 478 SUPERFAMILY SSF53720 3 477 1.44E-159 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS16015 6131a04eaf47e44b6b31527e491254fd 478 Pfam PF00171 Aldehyde dehydrogenase family 12 474 1.1E-159 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 Gene3D G3DSA:1.10.357.20 317 490 1.4E-33 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 TIGRFAM TIGR00400 mgtE: magnesium transporter 59 489 1.4E-82 T 29-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 Pfam PF00571 CBS domain 178 234 6.1E-5 T 29-03-2018 IPR000644 CBS domain CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 Pfam PF00571 CBS domain 242 296 2.4E-6 T 29-03-2018 IPR000644 CBS domain CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 SUPERFAMILY SSF54631 177 312 2.4E-27 T 29-03-2018 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 Pfam PF01769 Divalent cation transporter 361 482 1.5E-22 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 Gene3D G3DSA:3.10.580.10 226 306 8.9E-14 T 29-03-2018 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 SMART SM00116 185 238 1.2 T 29-03-2018 IPR000644 CBS domain CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 SMART SM00116 249 297 0.0023 T 29-03-2018 IPR000644 CBS domain CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 SUPERFAMILY SSF161093 318 489 5.49E-43 T 29-03-2018 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 SUPERFAMILY SSF158791 56 175 2.62E-28 T 29-03-2018 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 Gene3D G3DSA:1.25.60.10 42 169 3.3E-22 T 29-03-2018 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 Gene3D G3DSA:3.10.580.10 170 225 0.0063 T 29-03-2018 CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 SMART SM00924 75 178 1.9E-38 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CVS48_RS02375 d84d7b7259503ee99dcd1e45e48f9727 490 Pfam PF03448 MgtE intracellular N domain 75 176 1.2E-26 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 ProSitePatterns PS00211 ABC transporters family signature. 461 475 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 Gene3D G3DSA:3.40.50.300 22 303 7.6E-50 T 29-03-2018 CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 Pfam PF12848 ABC transporter 244 331 2.1E-18 T 29-03-2018 IPR032781 ABC-transporter extension domain CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 Gene3D G3DSA:3.40.50.300 304 554 1.0E-45 T 29-03-2018 CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 SUPERFAMILY SSF52540 319 547 4.56E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 SUPERFAMILY SSF52540 26 257 3.12E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 Pfam PF00005 ABC transporter 359 489 8.4E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 Pfam PF00005 ABC transporter 38 204 1.9E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 SMART SM00382 365 534 1.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19880 9aa823d0caf1bea2e3c4d0cf0e9ef1ff 554 SMART SM00382 46 258 2.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS20805 ff0769347bbeca48c4f6e70fe5efe896 362 SUPERFAMILY SSF51395 2 358 4.58E-121 T 29-03-2018 CVS48_RS20805 ff0769347bbeca48c4f6e70fe5efe896 362 Gene3D G3DSA:3.20.20.70 1 362 1.2E-125 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS20805 ff0769347bbeca48c4f6e70fe5efe896 362 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 336 1.7E-84 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 Gene3D G3DSA:3.50.30.10 153 273 1.6E-27 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 Pfam PF05524 PEP-utilising enzyme, N-terminal 19 141 1.8E-26 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 SUPERFAMILY SSF52009 140 264 1.96E-31 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 SUPERFAMILY SSF47831 39 158 4.05E-30 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 Gene3D G3DSA:1.10.274.10 39 152 2.3E-32 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 17 564 9.4E-155 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 PIRSF PIRSF000732 14 580 3.0E-199 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 270 559 2.0E-105 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 203 214 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 312 331 1.4E-25 T 29-03-2018 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 518 530 1.4E-25 T 29-03-2018 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 465 480 1.4E-25 T 29-03-2018 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 482 497 1.4E-25 T 29-03-2018 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 Gene3D G3DSA:3.20.20.60 274 582 1.9E-87 T 29-03-2018 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 SUPERFAMILY SSF51621 269 563 3.66E-99 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 Pfam PF00391 PEP-utilising enzyme, mobile domain 173 244 1.8E-21 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CVS48_RS15145 0f12da0701c7840581a069fc93145e37 585 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 465 483 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CVS48_RS25600 6f0b615b1a7f6baae42ef0283de3fa8d 141 SUPERFAMILY SSF49764 18 141 5.98E-34 T 29-03-2018 IPR008978 HSP20-like chaperone CVS48_RS25600 6f0b615b1a7f6baae42ef0283de3fa8d 141 Gene3D G3DSA:2.60.40.790 4 141 2.9E-30 T 29-03-2018 IPR008978 HSP20-like chaperone CVS48_RS25600 6f0b615b1a7f6baae42ef0283de3fa8d 141 Pfam PF00011 Hsp20/alpha crystallin family 40 140 1.4E-17 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CVS48_RS04655 ddec1555cb915dc46b808a7ed873f842 381 Gene3D G3DSA:3.40.710.10 28 380 9.2E-70 T 29-03-2018 CVS48_RS04655 ddec1555cb915dc46b808a7ed873f842 381 Pfam PF00144 Beta-lactamase 48 368 9.2E-55 T 29-03-2018 IPR001466 Beta-lactamase-related CVS48_RS04655 ddec1555cb915dc46b808a7ed873f842 381 SUPERFAMILY SSF56601 48 369 3.27E-66 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS01405 32902eee7ba63a0dc43d65a222b3606f 343 Gene3D G3DSA:1.10.1200.80 256 333 1.1E-22 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CVS48_RS01405 32902eee7ba63a0dc43d65a222b3606f 343 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 3 326 49.504 T 29-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 CVS48_RS01405 32902eee7ba63a0dc43d65a222b3606f 343 Pfam PF01207 Dihydrouridine synthase (Dus) 16 314 4.9E-97 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CVS48_RS01405 32902eee7ba63a0dc43d65a222b3606f 343 Gene3D G3DSA:3.20.20.70 8 252 3.0E-53 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS01405 32902eee7ba63a0dc43d65a222b3606f 343 PIRSF PIRSF006621 2 329 1.0E-99 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CVS48_RS01405 32902eee7ba63a0dc43d65a222b3606f 343 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 5 323 5.0E-117 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CVS48_RS01405 32902eee7ba63a0dc43d65a222b3606f 343 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CVS48_RS01405 32902eee7ba63a0dc43d65a222b3606f 343 SUPERFAMILY SSF51395 12 323 8.06E-87 T 29-03-2018 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 185 207 6.9E-36 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 24 49 6.9E-36 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 54 69 6.9E-36 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 75 95 6.9E-36 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 97 117 6.9E-36 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 143 169 6.9E-36 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 SUPERFAMILY SSF55961 159 438 1.65E-53 T 29-03-2018 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 Gene3D G3DSA:2.102.10.10 30 146 2.7E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 SUPERFAMILY SSF50022 7 156 4.71E-44 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 198 430 7.3E-9 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 Pfam PF00355 Rieske [2Fe-2S] domain 40 124 4.0E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS03380 d38e768b9891d64e1920b43cf46774e6 447 Gene3D G3DSA:3.90.380.10 147 439 2.4E-51 T 29-03-2018 CVS48_RS20245 c179e97e4700317d6911b1a5c410b455 244 Gene3D G3DSA:3.40.190.10 102 190 1.9E-18 T 29-03-2018 CVS48_RS20245 c179e97e4700317d6911b1a5c410b455 244 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 30 43 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CVS48_RS20245 c179e97e4700317d6911b1a5c410b455 244 SUPERFAMILY SSF53850 2 228 3.78E-57 T 29-03-2018 CVS48_RS20245 c179e97e4700317d6911b1a5c410b455 244 SMART SM00062 6 228 5.0E-58 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS20245 c179e97e4700317d6911b1a5c410b455 244 Gene3D G3DSA:3.40.190.10 1 101 6.0E-28 T 29-03-2018 CVS48_RS20245 c179e97e4700317d6911b1a5c410b455 244 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 7 226 1.3E-55 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 Gene3D G3DSA:2.40.50.230 420 521 4.8E-27 T 29-03-2018 IPR006531 Gp5 N-terminal CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 SUPERFAMILY SSF55486 2513 2588 5.57E-5 T 29-03-2018 CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 SUPERFAMILY SSF55486 2638 2645 5.57E-5 T 29-03-2018 CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 Pfam PF05954 Phage late control gene D protein (GPD) 47 376 2.2E-80 T 29-03-2018 CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 41 575 4.4E-85 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 32 568 1.3E-94 T 29-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 709 855 6.0E-38 T 29-03-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 SUPERFAMILY SSF69279 228 416 2.21E-15 T 29-03-2018 CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 552 659 2.5E-32 T 29-03-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 Gene3D G3DSA:3.40.390.10 2208 2587 0.0011 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 Gene3D G3DSA:3.55.50.10 116 215 7.6E-28 T 29-03-2018 CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 SUPERFAMILY SSF69349 511 573 9.42E-7 T 29-03-2018 CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 SUPERFAMILY SSF69255 414 521 7.06E-21 T 29-03-2018 CVS48_RS02140 8b9344ceab43617b25a26af917aaf4c3 2670 SUPERFAMILY SSF69279 35 211 3.4E-48 T 29-03-2018 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 113 126 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 PIRSF PIRSF000185 19 429 2.7E-160 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 194 426 9.1E-77 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 Gene3D G3DSA:3.40.50.10860 50 193 8.3E-54 T 29-03-2018 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 48 176 2.5E-54 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 227 247 4.6E-33 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 185 207 4.6E-33 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 4.6E-33 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 105 119 4.6E-33 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 Gene3D G3DSA:3.40.50.720 194 429 9.2E-77 T 29-03-2018 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 SUPERFAMILY SSF51735 194 428 9.0E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 SMART SM00839 196 426 3.7E-99 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS17340 956c1df384ee404df7160f3fdfc79ab2 429 SUPERFAMILY SSF53223 17 196 3.52E-67 T 29-03-2018 CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 Gene3D G3DSA:1.10.287.130 263 335 9.0E-10 T 29-03-2018 CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 SUPERFAMILY SSF55874 328 493 1.96E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 SMART SM00387 381 495 4.8E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 389 493 1.8E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 Gene3D G3DSA:3.30.565.10 345 507 3.9E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 473 5.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 450 5.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 436 5.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 492 5.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 SUPERFAMILY SSF47384 263 337 5.89E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 Pfam PF00512 His Kinase A (phospho-acceptor) domain 273 337 2.7E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS14890 90db45f949a944612b8061a3b8d3dd24 507 SMART SM00388 272 339 1.6E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS26605 775cd179e67935b0a6a066a751e6a1ae 372 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 9 372 38.628 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CVS48_RS26605 775cd179e67935b0a6a066a751e6a1ae 372 Gene3D G3DSA:2.30.30.280 220 292 1.5E-25 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CVS48_RS26605 775cd179e67935b0a6a066a751e6a1ae 372 Pfam PF03054 tRNA methyl transferase 10 371 6.9E-130 T 29-03-2018 CVS48_RS26605 775cd179e67935b0a6a066a751e6a1ae 372 Gene3D G3DSA:3.40.50.620 2 219 1.6E-61 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS26605 775cd179e67935b0a6a066a751e6a1ae 372 SUPERFAMILY SSF52402 7 251 4.41E-57 T 29-03-2018 CVS48_RS26605 775cd179e67935b0a6a066a751e6a1ae 372 Gene3D G3DSA:2.40.30.10 294 372 3.3E-23 T 29-03-2018 CVS48_RS26605 775cd179e67935b0a6a066a751e6a1ae 372 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 10 371 3.3E-128 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CVS48_RS11745 b69d1dce914face8c51fe36efd9740a9 144 Pfam PF07883 Cupin domain 61 130 1.3E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS11745 b69d1dce914face8c51fe36efd9740a9 144 SUPERFAMILY SSF51182 42 130 3.71E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS11745 b69d1dce914face8c51fe36efd9740a9 144 Gene3D G3DSA:2.60.120.10 17 142 1.9E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS18365 d9295db0f3168b1713c2af740d8b21b7 906 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 7 904 8.3E-294 T 29-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 CVS48_RS18365 d9295db0f3168b1713c2af740d8b21b7 906 SUPERFAMILY SSF51445 498 799 5.61E-129 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18365 d9295db0f3168b1713c2af740d8b21b7 906 SUPERFAMILY SSF51445 6 169 5.61E-129 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18365 d9295db0f3168b1713c2af740d8b21b7 906 SUPERFAMILY SSF51445 214 459 5.61E-129 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18365 d9295db0f3168b1713c2af740d8b21b7 906 Pfam PF00128 Alpha amylase, catalytic domain 27 100 5.4E-15 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18365 d9295db0f3168b1713c2af740d8b21b7 906 SMART SM00642 4 461 1.0E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18365 d9295db0f3168b1713c2af740d8b21b7 906 Gene3D G3DSA:3.20.20.80 9 800 1.1E-106 T 29-03-2018 CVS48_RS14705 040e67acee9eeacbbde0b1d12339ad14 212 Pfam PF09976 Tetratricopeptide repeat-like domain 15 210 3.5E-54 T 29-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 CVS48_RS14705 040e67acee9eeacbbde0b1d12339ad14 212 Gene3D G3DSA:1.25.40.10 39 154 0.091 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS14705 040e67acee9eeacbbde0b1d12339ad14 212 PIRSF PIRSF006170 1 212 4.8E-50 T 29-03-2018 IPR026039 Uncharacterised protein family UPF0070 CVS48_RS14705 040e67acee9eeacbbde0b1d12339ad14 212 Gene3D G3DSA:1.25.20.10 155 197 0.16 T 29-03-2018 CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 Gene3D G3DSA:3.30.70.920 60 150 1.5E-18 T 29-03-2018 CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 4.1E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 SMART SM00344 5 111 1.1E-21 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 SUPERFAMILY SSF46785 4 59 7.05E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 2.9E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 2.9E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 2.9E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 SUPERFAMILY SSF54909 67 146 6.17E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 Pfam PF01037 Lrp/AsnC ligand binding domain 73 141 1.4E-17 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS26955 2927753ea743d20b6f06f26389a6e3ec 152 Gene3D G3DSA:1.10.10.10 1 56 1.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 Pfam PF12833 Helix-turn-helix domain 44 121 2.9E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 Gene3D G3DSA:1.10.10.60 76 122 9.3E-7 T 29-03-2018 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 SUPERFAMILY SSF46689 24 71 5.82E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 SUPERFAMILY SSF46689 74 123 8.51E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 SUPERFAMILY SSF53155 127 206 2.35E-19 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 SUPERFAMILY SSF46767 207 287 2.62E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 258 264 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 Gene3D G3DSA:3.30.160.70 123 205 1.5E-21 T 29-03-2018 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 Gene3D G3DSA:1.10.10.60 19 75 2.3E-16 T 29-03-2018 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 209 287 1.2E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 Gene3D G3DSA:1.10.10.10 206 290 1.3E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 SMART SM00342 38 120 6.0E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS17220 e74c44d06faeed029340374e9ff6c214 291 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 208 287 5.6E-33 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS00745 e44c2f687741ff08a3e6ff4d86e561c4 249 Pfam PF14348 Domain of unknown function (DUF4400) 51 246 1.4E-74 T 29-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type CVS48_RS00745 e44c2f687741ff08a3e6ff4d86e561c4 249 TIGRFAM TIGR03747 conj_TIGR03747: integrating conjugative element membrane protein, PFL_4697 family 15 249 5.7E-101 T 29-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type CVS48_RS07445 6e4a7b692ddab1d6139e840715204b21 476 SUPERFAMILY SSF56059 322 467 3.54E-61 T 29-03-2018 CVS48_RS07445 6e4a7b692ddab1d6139e840715204b21 476 SUPERFAMILY SSF56059 21 215 3.54E-61 T 29-03-2018 CVS48_RS07445 6e4a7b692ddab1d6139e840715204b21 476 Pfam PF14403 Circularly permuted ATP-grasp type 2 77 452 7.8E-166 T 29-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 CVS48_RS07445 6e4a7b692ddab1d6139e840715204b21 476 Gene3D G3DSA:3.30.470.20 35 178 0.076 T 29-03-2018 CVS48_RS07445 6e4a7b692ddab1d6139e840715204b21 476 Gene3D G3DSA:3.30.470.20 341 468 1.7E-4 T 29-03-2018 CVS48_RS07445 6e4a7b692ddab1d6139e840715204b21 476 PIRSF PIRSF005522 1 476 4.0E-228 T 29-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 330 7.5E-109 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 Pfam PF09190 DALR domain 359 413 1.9E-15 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 SMART SM00840 359 414 7.2E-22 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 483 1.2E-146 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 483 36.635 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 225 246 4.9E-28 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 4.9E-28 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 4.9E-28 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 194 212 4.9E-28 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 Gene3D G3DSA:3.40.50.620 1 322 8.0E-73 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 Gene3D G3DSA:1.20.120.640 323 406 7.5E-18 T 29-03-2018 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 SUPERFAMILY SSF47323 333 482 1.06E-31 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS24055 9d98e7c271496ec5ddf4073ec1057824 484 SUPERFAMILY SSF52374 2 331 1.04E-82 T 29-03-2018 CVS48_RS05190 38a13b407aed162a1a23e2016c2c6cea 286 PRINTS PR00603 Cytochrome C1 signature 232 251 1.9E-5 T 29-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CVS48_RS05190 38a13b407aed162a1a23e2016c2c6cea 286 PRINTS PR00603 Cytochrome C1 signature 251 266 1.9E-5 T 29-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CVS48_RS05190 38a13b407aed162a1a23e2016c2c6cea 286 PRINTS PR00603 Cytochrome C1 signature 44 63 1.9E-5 T 29-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CVS48_RS05190 38a13b407aed162a1a23e2016c2c6cea 286 SUPERFAMILY SSF46626 227 250 4.16E-48 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS05190 38a13b407aed162a1a23e2016c2c6cea 286 SUPERFAMILY SSF46626 18 167 4.16E-48 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS05190 38a13b407aed162a1a23e2016c2c6cea 286 Pfam PF02167 Cytochrome C1 family 34 284 2.0E-18 T 29-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CVS48_RS05190 38a13b407aed162a1a23e2016c2c6cea 286 Gene3D G3DSA:1.20.5.100 256 285 2.5E-9 T 29-03-2018 CVS48_RS05190 38a13b407aed162a1a23e2016c2c6cea 286 Gene3D G3DSA:1.10.760.10 25 251 1.5E-55 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20215 ba2bb55accd4a899b2d8818f79d663ed 1064 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 291 711 1.4E-144 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS20215 ba2bb55accd4a899b2d8818f79d663ed 1064 Pfam PF02811 PHP domain 10 121 8.5E-16 T 29-03-2018 IPR004013 PHP domain GO:0003824 CVS48_RS20215 ba2bb55accd4a899b2d8818f79d663ed 1064 SMART SM00481 9 76 2.5E-11 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CVS48_RS20215 ba2bb55accd4a899b2d8818f79d663ed 1064 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 8 1064 13.946 T 29-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS20215 ba2bb55accd4a899b2d8818f79d663ed 1064 SUPERFAMILY SSF89550 13 69 3.34E-5 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CVS48_RS20215 ba2bb55accd4a899b2d8818f79d663ed 1064 Gene3D G3DSA:2.40.50.140 944 1059 7.2E-7 T 29-03-2018 CVS48_RS20215 ba2bb55accd4a899b2d8818f79d663ed 1064 Pfam PF14579 Helix-hairpin-helix motif 787 895 4.0E-20 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS20215 ba2bb55accd4a899b2d8818f79d663ed 1064 Gene3D G3DSA:3.20.20.140 7 250 3.6E-29 T 29-03-2018 CVS48_RS20215 ba2bb55accd4a899b2d8818f79d663ed 1064 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 9 1008 5.5E-156 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS14840 f068182bb29b1a2cdb4390f449d6427d 281 Pfam PF00482 Type II secretion system (T2SS), protein F 114 238 1.3E-19 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS14910 b6875592222d19fe95ea74db6aa2e305 275 Gene3D G3DSA:3.30.2010.10 69 166 3.0E-24 T 29-03-2018 CVS48_RS14910 b6875592222d19fe95ea74db6aa2e305 275 Pfam PF01435 Peptidase family M48 78 261 2.4E-37 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CVS48_RS23490 5a2cdbf4f6c69bf6fac11cf22eaa774e 93 SUPERFAMILY SSF47413 19 89 2.52E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS23490 5a2cdbf4f6c69bf6fac11cf22eaa774e 93 Gene3D G3DSA:3.30.1190.10 51 93 7.1E-8 T 29-03-2018 CVS48_RS23490 5a2cdbf4f6c69bf6fac11cf22eaa774e 93 Gene3D G3DSA:1.10.10.10 8 50 9.7E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23490 5a2cdbf4f6c69bf6fac11cf22eaa774e 93 Pfam PF13744 Helix-turn-helix domain 13 90 1.3E-23 T 29-03-2018 CVS48_RS25845 21549488bd726768f5d4bf684e7a2eda 314 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 153 2.4E-29 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CVS48_RS25845 21549488bd726768f5d4bf684e7a2eda 314 SUPERFAMILY SSF51735 1 133 3.26E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25845 21549488bd726768f5d4bf684e7a2eda 314 Gene3D G3DSA:3.40.50.720 1 182 3.0E-29 T 29-03-2018 CVS48_RS25845 21549488bd726768f5d4bf684e7a2eda 314 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 308 2.3E-70 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CVS48_RS25845 21549488bd726768f5d4bf684e7a2eda 314 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 183 307 6.0E-36 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CVS48_RS25845 21549488bd726768f5d4bf684e7a2eda 314 Gene3D G3DSA:1.10.1040.10 183 314 8.4E-40 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS25845 21549488bd726768f5d4bf684e7a2eda 314 SUPERFAMILY SSF48179 183 307 2.21E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 Gene3D G3DSA:4.10.320.10 117 166 2.8E-14 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 Gene3D G3DSA:2.40.50.100 47 116 1.6E-7 T 29-03-2018 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 Gene3D G3DSA:3.30.559.10 167 407 7.2E-88 T 29-03-2018 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 Gene3D G3DSA:3.90.1170.30 1 46 2.0E-13 T 29-03-2018 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 SUPERFAMILY SSF52777 179 408 3.87E-87 T 29-03-2018 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 179 407 2.7E-79 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 Pfam PF00364 Biotin-requiring enzyme 5 77 4.8E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 5 408 1.2E-168 T 29-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 Pfam PF02817 e3 binding domain 117 150 7.3E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 SUPERFAMILY SSF51230 2 96 4.45E-26 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS27805 6f7499e0c618b64aa08c1a20c973696e 409 SUPERFAMILY SSF47005 111 152 1.7E-9 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS06580 5a35695acae66d8f6576f4c55b68393b 145 Gene3D G3DSA:3.30.428.10 1 142 1.5E-29 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CVS48_RS06580 5a35695acae66d8f6576f4c55b68393b 145 SUPERFAMILY SSF54197 3 139 1.42E-31 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CVS48_RS06580 5a35695acae66d8f6576f4c55b68393b 145 PRINTS PR00332 Histidine triad family signature 6 22 3.6E-14 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CVS48_RS06580 5a35695acae66d8f6576f4c55b68393b 145 PRINTS PR00332 Histidine triad family signature 89 99 3.6E-14 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CVS48_RS06580 5a35695acae66d8f6576f4c55b68393b 145 PRINTS PR00332 Histidine triad family signature 27 45 3.6E-14 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CVS48_RS06580 5a35695acae66d8f6576f4c55b68393b 145 Pfam PF01230 HIT domain 13 103 1.8E-16 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CVS48_RS22825 127625c64655f79775a02277189be5ee 603 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 532 577 1.1E-6 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS22825 127625c64655f79775a02277189be5ee 603 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 263 5.9E-8 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS22825 127625c64655f79775a02277189be5ee 603 SMART SM00382 27 232 2.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22825 127625c64655f79775a02277189be5ee 603 SMART SM00382 337 529 1.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22825 127625c64655f79775a02277189be5ee 603 Gene3D G3DSA:3.40.50.300 298 582 3.6E-73 T 29-03-2018 CVS48_RS22825 127625c64655f79775a02277189be5ee 603 Gene3D G3DSA:3.40.50.300 1 276 3.3E-70 T 29-03-2018 CVS48_RS22825 127625c64655f79775a02277189be5ee 603 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS22825 127625c64655f79775a02277189be5ee 603 SUPERFAMILY SSF52540 302 552 1.25E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22825 127625c64655f79775a02277189be5ee 603 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS22825 127625c64655f79775a02277189be5ee 603 SUPERFAMILY SSF52540 1 254 8.64E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22825 127625c64655f79775a02277189be5ee 603 Pfam PF00005 ABC transporter 329 479 4.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22825 127625c64655f79775a02277189be5ee 603 Pfam PF00005 ABC transporter 19 182 8.7E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS21935 ecb8694d3505287020b723fd7205774b 180 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 139 4.4E-63 T 29-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 CVS48_RS21935 ecb8694d3505287020b723fd7205774b 180 SUPERFAMILY SSF46785 2 137 6.62E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21935 ecb8694d3505287020b723fd7205774b 180 Pfam PF02082 Transcriptional regulator 1 83 3.3E-27 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CVS48_RS21935 ecb8694d3505287020b723fd7205774b 180 Gene3D G3DSA:1.10.10.10 1 146 4.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21935 ecb8694d3505287020b723fd7205774b 180 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 136 9.5E-42 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CVS48_RS19590 abae3978076b54fb26297237ececc75c 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 216 8.4E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19590 abae3978076b54fb26297237ececc75c 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 4.2E-31 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS19590 abae3978076b54fb26297237ececc75c 218 Gene3D G3DSA:1.10.3720.10 1 217 5.2E-41 T 29-03-2018 CVS48_RS19590 abae3978076b54fb26297237ececc75c 218 SUPERFAMILY SSF161098 13 201 5.23E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05110 fcc36fdff472d03edc073848ac7e2420 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 195 42.078 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CVS48_RS05110 fcc36fdff472d03edc073848ac7e2420 195 Gene3D G3DSA:3.30.230.40 1 88 1.5E-34 T 29-03-2018 CVS48_RS05110 fcc36fdff472d03edc073848ac7e2420 195 SUPERFAMILY SSF54211 1 85 1.77E-33 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS05110 fcc36fdff472d03edc073848ac7e2420 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CVS48_RS05110 fcc36fdff472d03edc073848ac7e2420 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CVS48_RS05110 fcc36fdff472d03edc073848ac7e2420 195 SUPERFAMILY SSF54211 87 179 1.19E-33 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS05110 fcc36fdff472d03edc073848ac7e2420 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 1.1E-61 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CVS48_RS05110 fcc36fdff472d03edc073848ac7e2420 195 Gene3D G3DSA:3.30.230.40 90 195 2.4E-31 T 29-03-2018 CVS48_RS03625 013ffacfec9ae862a10e4e938e8886aa 256 Gene3D G3DSA:3.40.50.150 26 254 9.9E-43 T 29-03-2018 CVS48_RS03625 013ffacfec9ae862a10e4e938e8886aa 256 SUPERFAMILY SSF53335 23 245 1.41E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS03625 013ffacfec9ae862a10e4e938e8886aa 256 Pfam PF08241 Methyltransferase domain 49 145 9.5E-24 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CVS48_RS24065 eb64fe411ec9d569071d40d9215f2e3f 169 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 41 58 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CVS48_RS24065 eb64fe411ec9d569071d40d9215f2e3f 169 Gene3D G3DSA:2.40.100.10 1 169 1.1E-49 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS24065 eb64fe411ec9d569071d40d9215f2e3f 169 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 166 1.5E-45 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CVS48_RS24065 eb64fe411ec9d569071d40d9215f2e3f 169 PIRSF PIRSF001467 2 169 1.7E-25 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CVS48_RS24065 eb64fe411ec9d569071d40d9215f2e3f 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 1.4E-11 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CVS48_RS24065 eb64fe411ec9d569071d40d9215f2e3f 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 46 58 1.4E-11 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CVS48_RS24065 eb64fe411ec9d569071d40d9215f2e3f 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 123 138 1.4E-11 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CVS48_RS24065 eb64fe411ec9d569071d40d9215f2e3f 169 SUPERFAMILY SSF50891 7 168 4.82E-57 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS15655 c13baaac6e92176cd7e92dba15f570aa 247 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 67 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CVS48_RS15655 c13baaac6e92176cd7e92dba15f570aa 247 SUPERFAMILY SSF48498 93 207 5.56E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS15655 c13baaac6e92176cd7e92dba15f570aa 247 Gene3D G3DSA:1.10.10.60 15 71 2.2E-16 T 29-03-2018 CVS48_RS15655 c13baaac6e92176cd7e92dba15f570aa 247 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 3.6E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS15655 c13baaac6e92176cd7e92dba15f570aa 247 SUPERFAMILY SSF46689 11 93 6.98E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS15655 c13baaac6e92176cd7e92dba15f570aa 247 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS15655 c13baaac6e92176cd7e92dba15f570aa 247 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS15655 c13baaac6e92176cd7e92dba15f570aa 247 Gene3D G3DSA:1.10.357.10 72 211 1.2E-21 T 29-03-2018 CVS48_RS15655 c13baaac6e92176cd7e92dba15f570aa 247 Pfam PF08359 YsiA-like protein, C-terminal region 78 201 2.6E-8 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CVS48_RS03065 820e4ee410250245e2cf2e315e7d97f7 338 Gene3D G3DSA:3.40.190.10 143 338 7.5E-21 T 29-03-2018 CVS48_RS03065 820e4ee410250245e2cf2e315e7d97f7 338 Gene3D G3DSA:3.40.190.10 33 133 1.3E-7 T 29-03-2018 CVS48_RS03065 820e4ee410250245e2cf2e315e7d97f7 338 SUPERFAMILY SSF53850 45 276 7.5E-28 T 29-03-2018 CVS48_RS03065 820e4ee410250245e2cf2e315e7d97f7 338 Pfam PF09084 NMT1/THI5 like 51 261 1.2E-18 T 29-03-2018 IPR015168 SsuA/THI5-like CVS48_RS03415 fa31a1e5c84a1291aeeb6f0f91716cd6 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 128 1.4E-11 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS03415 fa31a1e5c84a1291aeeb6f0f91716cd6 389 SUPERFAMILY SSF56645 12 248 2.75E-62 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS03415 fa31a1e5c84a1291aeeb6f0f91716cd6 389 Gene3D G3DSA:2.40.110.10 131 226 4.8E-35 T 29-03-2018 CVS48_RS03415 fa31a1e5c84a1291aeeb6f0f91716cd6 389 SUPERFAMILY SSF47203 236 388 1.03E-47 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS03415 fa31a1e5c84a1291aeeb6f0f91716cd6 389 Gene3D G3DSA:1.10.540.10 2 130 1.1E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS03415 fa31a1e5c84a1291aeeb6f0f91716cd6 389 Gene3D G3DSA:1.20.140.10 227 389 3.8E-51 T 29-03-2018 CVS48_RS03415 fa31a1e5c84a1291aeeb6f0f91716cd6 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 225 2.0E-23 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS03415 fa31a1e5c84a1291aeeb6f0f91716cd6 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 134 146 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS03415 fa31a1e5c84a1291aeeb6f0f91716cd6 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 386 1.2E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 12 464 6.3E-185 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 PIRSF PIRSF001109 1 472 3.3E-188 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 SMART SM00996 11 471 0.0 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 11 471 6.0E-145 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 SUPERFAMILY SSF51735 232 391 3.16E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 254 270 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 SMART SM00997 232 391 2.3E-112 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 83 97 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 SUPERFAMILY SSF52283 184 231 6.8E-112 T 29-03-2018 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 SUPERFAMILY SSF52283 392 472 6.8E-112 T 29-03-2018 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 SUPERFAMILY SSF52283 9 148 6.8E-112 T 29-03-2018 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 7 464 48.367 T 29-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 232 391 3.1E-80 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 Gene3D G3DSA:3.40.50.1480 250 445 3.6E-83 T 29-03-2018 CVS48_RS07410 d51a5dd4906fc2d3ea4c1da46bd3b045 472 Gene3D G3DSA:3.40.50.1480 2 249 4.3E-89 T 29-03-2018 CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 Gene3D G3DSA:3.40.50.720 159 258 1.6E-23 T 29-03-2018 CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 Gene3D G3DSA:3.40.50.720 6 158 2.8E-46 T 29-03-2018 CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 SUPERFAMILY SSF51735 9 254 6.44E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 254 2.7E-61 T 29-03-2018 CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.1E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.1E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.1E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.1E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14145 3e40bc984f295f8fb828e8b11f6cf866 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS25490 214e5ccf4fb215075934552f26f73bcc 223 SMART SM00965 58 109 1.0E-10 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS25490 214e5ccf4fb215075934552f26f73bcc 223 Pfam PF07660 Secretin and TonB N terminus short domain 59 108 6.6E-7 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS23760 1a5e5e9c39138c96f8cf0ac77d7ad63a 476 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 10 475 1.7E-199 T 29-03-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CVS48_RS23760 1a5e5e9c39138c96f8cf0ac77d7ad63a 476 SUPERFAMILY SSF51182 192 475 2.49E-80 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS23760 1a5e5e9c39138c96f8cf0ac77d7ad63a 476 Gene3D G3DSA:2.60.120.10 344 453 3.5E-31 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS23760 1a5e5e9c39138c96f8cf0ac77d7ad63a 476 SUPERFAMILY SSF53448 8 285 2.48E-67 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS23760 1a5e5e9c39138c96f8cf0ac77d7ad63a 476 Gene3D G3DSA:3.90.550.10 8 343 2.5E-94 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS23760 1a5e5e9c39138c96f8cf0ac77d7ad63a 476 Pfam PF00483 Nucleotidyl transferase 10 293 5.7E-59 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CVS48_RS23760 1a5e5e9c39138c96f8cf0ac77d7ad63a 476 Pfam PF01050 Mannose-6-phosphate isomerase 321 471 4.7E-71 T 29-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CVS48_RS02875 5fd73a0c893066e044bc71a34f079981 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 325 1.8E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS02875 5fd73a0c893066e044bc71a34f079981 329 PIRSF PIRSF017082 1 329 7.3E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS02875 5fd73a0c893066e044bc71a34f079981 329 Gene3D G3DSA:3.40.190.10 129 237 7.8E-11 T 29-03-2018 CVS48_RS02875 5fd73a0c893066e044bc71a34f079981 329 SUPERFAMILY SSF53850 118 290 3.33E-12 T 29-03-2018 CVS48_RS05210 90559eec253ff500f7cc9bad2a6458b2 312 Gene3D G3DSA:3.20.20.150 1 307 2.5E-52 T 29-03-2018 CVS48_RS05210 90559eec253ff500f7cc9bad2a6458b2 312 Pfam PF01261 Xylose isomerase-like TIM barrel 37 258 5.2E-28 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CVS48_RS05210 90559eec253ff500f7cc9bad2a6458b2 312 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 8 303 1.2E-116 T 29-03-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 CVS48_RS05210 90559eec253ff500f7cc9bad2a6458b2 312 SUPERFAMILY SSF51658 10 303 1.23E-57 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CVS48_RS07725 c3e937087bd06105461af4caaf384684 269 Pfam PF00034 Cytochrome c 71 123 9.4E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07725 c3e937087bd06105461af4caaf384684 269 SUPERFAMILY SSF46626 154 243 1.63E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07725 c3e937087bd06105461af4caaf384684 269 SUPERFAMILY SSF46626 71 145 4.73E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07725 c3e937087bd06105461af4caaf384684 269 Gene3D G3DSA:1.10.760.10 144 243 3.2E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07725 c3e937087bd06105461af4caaf384684 269 Gene3D G3DSA:1.10.760.10 33 139 2.0E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07725 c3e937087bd06105461af4caaf384684 269 PIRSF PIRSF000005 16 245 9.0E-63 T 29-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 CVS48_RS02495 750f5044390ef7b847922f188dcf1cc5 576 SUPERFAMILY SSF56519 60 227 1.83E-45 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CVS48_RS02495 750f5044390ef7b847922f188dcf1cc5 576 Pfam PF00905 Penicillin binding protein transpeptidase domain 254 547 9.2E-67 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CVS48_RS02495 750f5044390ef7b847922f188dcf1cc5 576 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 213 4.9E-22 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CVS48_RS02495 750f5044390ef7b847922f188dcf1cc5 576 SUPERFAMILY SSF56601 179 562 1.73E-81 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS02495 750f5044390ef7b847922f188dcf1cc5 576 Gene3D G3DSA:3.90.1310.10 33 228 7.2E-45 T 29-03-2018 CVS48_RS02495 750f5044390ef7b847922f188dcf1cc5 576 Gene3D G3DSA:3.40.710.10 229 570 2.5E-75 T 29-03-2018 CVS48_RS02110 d6389604a1102170443e35206b37efd4 498 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 21 492 1.6E-218 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CVS48_RS02110 d6389604a1102170443e35206b37efd4 498 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 70 492 1.2E-191 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 Gene3D G3DSA:3.40.50.1980 22 206 6.3E-57 T 29-03-2018 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 PRINTS PR00691 Adhesin B signature 76 95 3.5E-16 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 PRINTS PR00691 Adhesin B signature 32 53 3.5E-16 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 PRINTS PR00691 Adhesin B signature 57 75 3.5E-16 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 PRINTS PR00691 Adhesin B signature 306 324 3.5E-16 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 Pfam PF01297 Zinc-uptake complex component A periplasmic 36 325 4.0E-85 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 Gene3D G3DSA:3.40.50.1980 207 328 1.9E-41 T 29-03-2018 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 PRINTS PR00690 Adhesin family signature 76 93 1.9E-17 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 PRINTS PR00690 Adhesin family signature 63 76 1.9E-17 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 PRINTS PR00690 Adhesin family signature 32 50 1.9E-17 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 PRINTS PR00690 Adhesin family signature 293 312 1.9E-17 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CVS48_RS07275 52bdf9e85ce12a8c61447040281b9647 329 SUPERFAMILY SSF53807 31 328 9.81E-91 T 29-03-2018 CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 Gene3D G3DSA:3.40.190.10 178 264 1.1E-9 T 29-03-2018 CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 Gene3D G3DSA:3.40.190.10 90 177 2.1E-15 T 29-03-2018 CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 SUPERFAMILY SSF53850 89 294 4.89E-32 T 29-03-2018 CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.8E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 Pfam PF03466 LysR substrate binding domain 87 291 1.2E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 SUPERFAMILY SSF46785 1 110 3.37E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01775 3db303d6bdc6af130238f8af4bfa8c64 301 Gene3D G3DSA:1.10.10.10 1 89 5.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20810 b0a75eb3db83078a851d8e69eeed078d 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 2.2E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20810 b0a75eb3db83078a851d8e69eeed078d 230 SUPERFAMILY SSF48498 77 183 2.49E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS20810 b0a75eb3db83078a851d8e69eeed078d 230 Gene3D G3DSA:1.10.357.10 61 184 1.2E-12 T 29-03-2018 CVS48_RS20810 b0a75eb3db83078a851d8e69eeed078d 230 Gene3D G3DSA:1.10.10.60 1 60 3.4E-17 T 29-03-2018 CVS48_RS20810 b0a75eb3db83078a851d8e69eeed078d 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 4.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20810 b0a75eb3db83078a851d8e69eeed078d 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 4.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20810 b0a75eb3db83078a851d8e69eeed078d 230 SUPERFAMILY SSF46689 1 70 3.69E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 SUPERFAMILY SSF69304 164 436 3.53E-52 T 29-03-2018 CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Gene3D G3DSA:2.120.10.30 331 439 3.7E-10 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Gene3D G3DSA:2.60.120.20 292 330 2.3E-14 T 29-03-2018 CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 SUPERFAMILY SSF52964 46 171 2.48E-31 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Gene3D G3DSA:2.130.10.150 175 291 3.2E-18 T 29-03-2018 CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Pfam PF07676 WD40-like Beta Propeller Repeat 289 324 1.1E-12 T 29-03-2018 IPR011659 WD40-like Beta Propeller CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Pfam PF07676 WD40-like Beta Propeller Repeat 333 366 2.2E-8 T 29-03-2018 IPR011659 WD40-like Beta Propeller CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Pfam PF07676 WD40-like Beta Propeller Repeat 245 279 2.0E-7 T 29-03-2018 IPR011659 WD40-like Beta Propeller CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Pfam PF07676 WD40-like Beta Propeller Repeat 207 235 7.7E-7 T 29-03-2018 IPR011659 WD40-like Beta Propeller CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Pfam PF04052 TolB amino-terminal domain 39 138 4.2E-23 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Gene3D G3DSA:3.40.50.10070 38 174 2.1E-30 T 29-03-2018 CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 30 435 1.6E-154 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 CVS48_RS02695 3e29ebf38e96c878a0a97f28a6b21cf7 439 Hamap MF_00671 Protein TolB [tolB]. 20 434 33.418 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.9E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 Gene3D G3DSA:3.40.190.10 89 180 1.7E-17 T 29-03-2018 CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 Gene3D G3DSA:3.40.190.10 181 268 2.4E-15 T 29-03-2018 CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 SUPERFAMILY SSF46785 2 113 3.04E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 SUPERFAMILY SSF53850 92 301 3.69E-34 T 29-03-2018 CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 Gene3D G3DSA:1.10.10.10 2 85 1.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 Pfam PF03466 LysR substrate binding domain 91 296 2.7E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25870 92bdefa0f75a1c58011ea6b11072ab6f 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22350 97386b802cfbc807a4d0db39275de8b9 427 SUPERFAMILY SSF103473 7 420 1.44E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS22350 97386b802cfbc807a4d0db39275de8b9 427 Gene3D G3DSA:1.20.1250.20 10 203 8.9E-24 T 29-03-2018 CVS48_RS22350 97386b802cfbc807a4d0db39275de8b9 427 Gene3D G3DSA:1.20.1250.20 231 425 9.5E-23 T 29-03-2018 CVS48_RS22350 97386b802cfbc807a4d0db39275de8b9 427 Pfam PF07690 Major Facilitator Superfamily 25 350 2.8E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS20335 1e73b77e72d1191018ba0fc3a1a30320 527 PIRSF PIRSF002741 16 527 1.7E-94 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS20335 1e73b77e72d1191018ba0fc3a1a30320 527 Gene3D G3DSA:3.40.190.10 203 302 9.8E-26 T 29-03-2018 CVS48_RS20335 1e73b77e72d1191018ba0fc3a1a30320 527 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 93 450 1.4E-77 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS20335 1e73b77e72d1191018ba0fc3a1a30320 527 SUPERFAMILY SSF53850 46 527 1.09E-112 T 29-03-2018 CVS48_RS20335 1e73b77e72d1191018ba0fc3a1a30320 527 Gene3D G3DSA:3.90.76.10 59 202 1.5E-35 T 29-03-2018 CVS48_RS20335 1e73b77e72d1191018ba0fc3a1a30320 527 Gene3D G3DSA:3.10.105.10 303 498 2.4E-33 T 29-03-2018 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 417 2.2E-21 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 SUPERFAMILY SSF48179 201 293 5.27E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 8 181 4.6E-34 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 203 291 4.1E-24 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 SUPERFAMILY SSF51735 8 192 4.91E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 PIRSF PIRSF500136 2 425 1.0E-152 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 8 412 4.1E-121 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 Gene3D G3DSA:1.20.5.170 202 224 1.9E-11 T 29-03-2018 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 SUPERFAMILY SSF52413 303 419 8.5E-30 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 SMART SM00984 318 418 1.4E-37 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 Gene3D G3DSA:3.40.50.720 5 200 2.5E-40 T 29-03-2018 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 Gene3D G3DSA:3.40.50.720 225 422 1.5E-57 T 29-03-2018 CVS48_RS10680 ab22b0c39190aa65e0c1540fd80ec524 425 PIRSF PIRSF000124 7 422 7.6E-55 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 Gene3D G3DSA:3.40.50.740 306 669 1.5E-64 T 29-03-2018 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 SMART SM00926 41 95 4.1E-12 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 42 94 2.0E-15 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 Hamap MF_01630 Nitrate reductase [napA]. 1 831 29.13 T 29-03-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042128|GO:0042597|GO:0051539|GO:0055114 KEGG: 00910+1.7.99.4 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 SUPERFAMILY SSF53706 38 705 7.98E-200 T 29-03-2018 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 Pfam PF01568 Molydopterin dinucleotide binding domain 717 825 1.0E-23 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 23 2.0E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 SUPERFAMILY SSF50692 690 831 6.42E-43 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 46 64 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 Gene3D G3DSA:2.20.25.90 34 100 1.1E-13 T 29-03-2018 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 Gene3D G3DSA:2.40.40.20 670 831 2.8E-35 T 29-03-2018 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 TIGRFAM TIGR01706 NAPA: periplasmic nitrate reductase, large subunit 3 831 0.0 T 29-03-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042128|GO:0042597|GO:0051539|GO:0055114 KEGG: 00910+1.7.99.4 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 Pfam PF00384 Molybdopterin oxidoreductase 98 571 2.0E-96 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS15760 d0ddb4afe68e5e27e04780b6ecdbfe31 831 Gene3D G3DSA:3.40.50.740 101 290 1.5E-40 T 29-03-2018 CVS48_RS10115 0249fe58ae63c2a7d50c6c2f51cced0a 266 Pfam PF09339 IclR helix-turn-helix domain 22 72 2.6E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS10115 0249fe58ae63c2a7d50c6c2f51cced0a 266 SUPERFAMILY SSF55781 78 263 4.12E-28 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS10115 0249fe58ae63c2a7d50c6c2f51cced0a 266 SUPERFAMILY SSF46785 20 93 4.05E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10115 0249fe58ae63c2a7d50c6c2f51cced0a 266 Gene3D G3DSA:1.10.10.10 2 81 1.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10115 0249fe58ae63c2a7d50c6c2f51cced0a 266 Gene3D G3DSA:3.30.450.40 92 266 3.4E-30 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS10115 0249fe58ae63c2a7d50c6c2f51cced0a 266 SMART SM00346 20 110 3.8E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS10115 0249fe58ae63c2a7d50c6c2f51cced0a 266 Pfam PF01614 Bacterial transcriptional regulator 141 260 1.7E-13 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS02660 2e61d979c73a6be222e2be372d4d5744 229 Pfam PF00072 Response regulator receiver domain 3 112 7.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS02660 2e61d979c73a6be222e2be372d4d5744 229 Gene3D G3DSA:3.40.50.2300 1 123 7.4E-33 T 29-03-2018 CVS48_RS02660 2e61d979c73a6be222e2be372d4d5744 229 SUPERFAMILY SSF52172 1 174 1.18E-36 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS02660 2e61d979c73a6be222e2be372d4d5744 229 SMART SM00448 1 112 7.4E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS02660 2e61d979c73a6be222e2be372d4d5744 229 Gene3D G3DSA:1.10.10.10 124 225 1.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02660 2e61d979c73a6be222e2be372d4d5744 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 218 1.3E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS02660 2e61d979c73a6be222e2be372d4d5744 229 SMART SM00862 145 218 5.1E-13 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 Gene3D G3DSA:1.10.10.10 1 85 3.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 SUPERFAMILY SSF46785 4 87 5.94E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 Gene3D G3DSA:3.40.190.10 89 178 1.2E-24 T 29-03-2018 CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 Pfam PF03466 LysR substrate binding domain 90 291 3.8E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.6E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 Gene3D G3DSA:3.40.190.10 179 266 1.7E-23 T 29-03-2018 CVS48_RS19415 ba7ea01c070181ea05bedbc661875ea1 304 SUPERFAMILY SSF53850 92 295 4.89E-46 T 29-03-2018 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 Gene3D G3DSA:3.50.50.60 1 131 7.7E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 Gene3D G3DSA:3.50.50.60 132 235 1.7E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 1.1E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 314 4.8E-119 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.7E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 1.7E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 1.7E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.7E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 1.7E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 200 216 1.7E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.7E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.7E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.7E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 SUPERFAMILY SSF51905 1 314 1.2E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 7.5E-40 T 29-03-2018 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 7.5E-40 T 29-03-2018 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 7.5E-40 T 29-03-2018 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.5E-40 T 29-03-2018 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 7.5E-40 T 29-03-2018 CVS48_RS00260 3d2e467bb3f4c05363d742f94f7fc994 319 Gene3D G3DSA:3.50.50.60 236 318 5.0E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27325 95652caef79327ee1c9ce5a173479148 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 43.516 T 29-03-2018 IPR022894 Oligoribonuclease GO:0000175 CVS48_RS27325 95652caef79327ee1c9ce5a173479148 181 Pfam PF00929 Exonuclease 9 170 1.6E-31 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CVS48_RS27325 95652caef79327ee1c9ce5a173479148 181 Gene3D G3DSA:3.30.420.10 2 181 3.7E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS27325 95652caef79327ee1c9ce5a173479148 181 SUPERFAMILY SSF53098 2 180 5.22E-49 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS27325 95652caef79327ee1c9ce5a173479148 181 SMART SM00479 7 180 6.9E-24 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CVS48_RS10685 c889b69a09623316a432a6116fc2abfc 341 Gene3D G3DSA:3.90.25.10 196 340 1.0E-33 T 29-03-2018 CVS48_RS10685 c889b69a09623316a432a6116fc2abfc 341 Gene3D G3DSA:3.40.50.720 17 195 6.6E-34 T 29-03-2018 CVS48_RS10685 c889b69a09623316a432a6116fc2abfc 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 264 1.7E-56 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS10685 c889b69a09623316a432a6116fc2abfc 341 PRINTS PR01713 Nucleotide sugar epimerase signature 234 249 8.0E-8 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS10685 c889b69a09623316a432a6116fc2abfc 341 PRINTS PR01713 Nucleotide sugar epimerase signature 45 61 8.0E-8 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS10685 c889b69a09623316a432a6116fc2abfc 341 PRINTS PR01713 Nucleotide sugar epimerase signature 258 273 8.0E-8 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS10685 c889b69a09623316a432a6116fc2abfc 341 PRINTS PR01713 Nucleotide sugar epimerase signature 302 319 8.0E-8 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS10685 c889b69a09623316a432a6116fc2abfc 341 SUPERFAMILY SSF51735 16 339 5.15E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 Pfam PF00271 Helicase conserved C-terminal domain 307 432 1.6E-13 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 Pfam PF04408 Helicase associated domain (HA2) 495 585 2.2E-15 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 SMART SM00847 492 597 2.2E-29 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 Pfam PF11898 Domain of unknown function (DUF3418) 751 1340 2.4E-214 T 29-03-2018 IPR024590 RNA helicase HrpA, C-terminal CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 SMART SM00490 331 432 4.3E-21 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 SMART SM00487 78 267 1.1E-26 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 SUPERFAMILY SSF52540 79 605 2.98E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 Gene3D G3DSA:3.40.50.300 79 238 2.1E-32 T 29-03-2018 CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 661 737 2.5E-16 T 29-03-2018 IPR011709 Domain of unknown function DUF1605 CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 Gene3D G3DSA:3.40.50.300 261 452 5.4E-48 T 29-03-2018 CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 SMART SM00382 95 398 5.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS26180 d5c014e27e178d5876f729ac3871fc0e 1344 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 66 1340 0.0 T 29-03-2018 IPR010222 RNA helicase HrpA GO:0004004 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 Gene3D G3DSA:1.10.760.10 250 331 1.8E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 SUPERFAMILY SSF46626 255 329 7.35E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 255 327 9.2E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 83 156 8.8E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 PRINTS PR00607 Class IE cytochrome C signature 131 143 7.4E-12 T 29-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 PRINTS PR00607 Class IE cytochrome C signature 146 157 7.4E-12 T 29-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 PRINTS PR00607 Class IE cytochrome C signature 92 103 7.4E-12 T 29-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 PRINTS PR00607 Class IE cytochrome C signature 103 113 7.4E-12 T 29-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 Gene3D G3DSA:1.10.760.10 74 188 5.2E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS03950 0980b4d5204e12176ee94dee9b7e5e6f 332 SUPERFAMILY SSF46626 66 162 4.73E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS28240 203da26ef28261e56e806ccada33381f 326 SUPERFAMILY SSF53187 8 314 3.18E-45 T 29-03-2018 CVS48_RS28240 203da26ef28261e56e806ccada33381f 326 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 34 314 1.0E-36 T 29-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CVS48_RS28240 203da26ef28261e56e806ccada33381f 326 Gene3D G3DSA:3.40.630.10 27 253 2.2E-25 T 29-03-2018 CVS48_RS28240 203da26ef28261e56e806ccada33381f 326 PIRSF PIRSF039012 3 320 2.0E-67 T 29-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 Pfam PF03466 LysR substrate binding domain 86 287 8.5E-22 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 Gene3D G3DSA:3.40.190.10 175 260 1.2E-12 T 29-03-2018 CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 Gene3D G3DSA:1.10.10.10 1 77 7.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 SUPERFAMILY SSF46785 1 75 4.19E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 54 1.6E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 Gene3D G3DSA:3.40.190.10 84 174 8.3E-12 T 29-03-2018 CVS48_RS17980 19ca1a5597a779fb63df09119ea542f4 294 SUPERFAMILY SSF53850 80 284 7.88E-41 T 29-03-2018 CVS48_RS11335 dea78c655d1f33a9541bdfd54cbcb0a1 393 Gene3D G3DSA:1.20.1250.20 207 393 2.0E-20 T 29-03-2018 CVS48_RS11335 dea78c655d1f33a9541bdfd54cbcb0a1 393 SUPERFAMILY SSF103473 10 391 1.44E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS11335 dea78c655d1f33a9541bdfd54cbcb0a1 393 Pfam PF07690 Major Facilitator Superfamily 21 353 6.5E-36 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS11335 dea78c655d1f33a9541bdfd54cbcb0a1 393 Gene3D G3DSA:1.20.1250.20 2 189 2.8E-25 T 29-03-2018 CVS48_RS08470 03333d868ae5a8f0712e7a82c85dba83 704 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 5 636 1.1E-222 T 29-03-2018 IPR022458 Conjugative coupling factor TraG/TraD CVS48_RS08470 03333d868ae5a8f0712e7a82c85dba83 704 Pfam PF12696 TraM recognition site of TraD and TraG 491 617 1.9E-10 T 29-03-2018 IPR032689 TraD/TraG, TraM recognition site CVS48_RS08470 03333d868ae5a8f0712e7a82c85dba83 704 TIGRFAM TIGR03754 conj_TOL_TraD: conjugative coupling factor TraD, PFGI-1 class 6 637 7.9E-246 T 29-03-2018 IPR022503 Conjugative coupling factor TraG/TraD, PFGI-1 CVS48_RS08470 03333d868ae5a8f0712e7a82c85dba83 704 SUPERFAMILY SSF52540 354 632 9.51E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08470 03333d868ae5a8f0712e7a82c85dba83 704 SUPERFAMILY SSF52540 137 300 9.51E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08470 03333d868ae5a8f0712e7a82c85dba83 704 Gene3D G3DSA:3.40.50.300 97 643 4.9E-26 T 29-03-2018 CVS48_RS29075 b719d75e09b1a7846995129a112d0bcb 204 Pfam PF13470 PIN domain 11 109 1.6E-15 T 29-03-2018 IPR002716 PIN domain CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 SUPERFAMILY SSF48179 500 597 5.78E-27 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 Gene3D G3DSA:1.10.1040.10 500 595 3.4E-22 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 306 454 7.8E-39 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 204 2.3E-29 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 SUPERFAMILY SSF48179 632 684 8.42E-7 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 Gene3D G3DSA:1.10.1040.10 634 691 0.033 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 Gene3D G3DSA:3.90.226.10 2 206 1.5E-46 T 29-03-2018 CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 SUPERFAMILY SSF51735 305 454 4.04E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 SUPERFAMILY SSF52096 7 263 5.15E-52 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 Gene3D G3DSA:3.40.50.720 262 499 1.8E-40 T 29-03-2018 CVS48_RS23850 cff9e5b81d557c384807d01ca1df75c9 697 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 501 590 1.8E-22 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS02485 337596cc539d279be48734f89b055990 389 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CVS48_RS02485 337596cc539d279be48734f89b055990 389 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 387 23.55 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CVS48_RS02485 337596cc539d279be48734f89b055990 389 Pfam PF00953 Glycosyl transferase family 4 99 307 2.6E-34 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CVS48_RS02485 337596cc539d279be48734f89b055990 389 ProSitePatterns PS01348 MraY family signature 2. 212 223 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CVS48_RS02485 337596cc539d279be48734f89b055990 389 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 389 4.3E-121 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CVS48_RS02485 337596cc539d279be48734f89b055990 389 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 2.6E-4 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 Gene3D G3DSA:3.40.190.10 85 178 2.3E-20 T 29-03-2018 CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 SUPERFAMILY SSF53850 86 287 3.53E-33 T 29-03-2018 CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 SUPERFAMILY SSF46785 7 110 3.55E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 Gene3D G3DSA:3.40.190.10 179 256 2.2E-15 T 29-03-2018 CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 Gene3D G3DSA:1.10.10.10 2 84 2.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03795 99ccc14ae50071d56bcecdc48560ed45 289 Pfam PF03466 LysR substrate binding domain 86 265 4.1E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS22845 64ee76cd2b754b37529ea0076b36e4d5 583 Gene3D G3DSA:3.40.630.10 319 467 1.1E-10 T 29-03-2018 CVS48_RS22845 64ee76cd2b754b37529ea0076b36e4d5 583 SUPERFAMILY SSF53187 326 523 5.95E-18 T 29-03-2018 CVS48_RS22085 9b7831e0884415b63e8d4c7350f64e6a 285 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 14 278 49.199 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CVS48_RS22085 9b7831e0884415b63e8d4c7350f64e6a 285 Gene3D G3DSA:3.20.20.70 29 275 4.3E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS22085 9b7831e0884415b63e8d4c7350f64e6a 285 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 19 276 9.6E-116 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CVS48_RS22085 9b7831e0884415b63e8d4c7350f64e6a 285 SUPERFAMILY SSF51569 7 280 2.93E-102 T 29-03-2018 CVS48_RS22085 9b7831e0884415b63e8d4c7350f64e6a 285 Pfam PF00793 DAHP synthetase I family 11 276 7.4E-68 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CVS48_RS11015 16b597b71a3ee049321fb3d52d9a2819 271 SUPERFAMILY SSF55781 76 270 6.21E-35 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS11015 16b597b71a3ee049321fb3d52d9a2819 271 Gene3D G3DSA:1.10.10.10 1 79 6.9E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11015 16b597b71a3ee049321fb3d52d9a2819 271 Gene3D G3DSA:3.30.450.40 91 271 7.1E-40 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS11015 16b597b71a3ee049321fb3d52d9a2819 271 SMART SM00346 18 108 1.6E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS11015 16b597b71a3ee049321fb3d52d9a2819 271 Pfam PF09339 IclR helix-turn-helix domain 20 70 4.6E-9 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS11015 16b597b71a3ee049321fb3d52d9a2819 271 Pfam PF01614 Bacterial transcriptional regulator 137 265 8.2E-11 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS11015 16b597b71a3ee049321fb3d52d9a2819 271 SUPERFAMILY SSF46785 18 92 6.65E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21400 58a1a9a742fd90d9a9ddcf7e9d03ab75 517 Gene3D G3DSA:1.20.1250.20 15 210 1.2E-20 T 29-03-2018 CVS48_RS21400 58a1a9a742fd90d9a9ddcf7e9d03ab75 517 Pfam PF07690 Major Facilitator Superfamily 26 421 2.2E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS21400 58a1a9a742fd90d9a9ddcf7e9d03ab75 517 SUPERFAMILY SSF103473 256 432 1.22E-33 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS21400 58a1a9a742fd90d9a9ddcf7e9d03ab75 517 SUPERFAMILY SSF103473 9 200 1.22E-33 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS21400 58a1a9a742fd90d9a9ddcf7e9d03ab75 517 Gene3D G3DSA:1.20.1250.20 266 513 4.0E-11 T 29-03-2018 CVS48_RS14895 8ad313ab8084a5b918b6a938a0db815b 656 Gene3D G3DSA:3.20.20.450 401 646 3.3E-31 T 29-03-2018 IPR001633 EAL domain CVS48_RS14895 8ad313ab8084a5b918b6a938a0db815b 656 Pfam PF00990 Diguanylate cyclase, GGDEF domain 236 390 3.9E-16 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS14895 8ad313ab8084a5b918b6a938a0db815b 656 SUPERFAMILY SSF141868 413 642 2.75E-29 T 29-03-2018 IPR001633 EAL domain CVS48_RS14895 8ad313ab8084a5b918b6a938a0db815b 656 Gene3D G3DSA:3.30.70.270 228 400 1.7E-22 T 29-03-2018 CVS48_RS14895 8ad313ab8084a5b918b6a938a0db815b 656 SMART SM00267 224 397 7.3E-10 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS14895 8ad313ab8084a5b918b6a938a0db815b 656 Pfam PF16448 LapD/MoxY periplasmic domain 27 146 8.7E-10 T 29-03-2018 IPR032244 LapD/MoxY, periplasmic domain CVS48_RS14895 8ad313ab8084a5b918b6a938a0db815b 656 Pfam PF00563 EAL domain 414 637 3.7E-28 T 29-03-2018 IPR001633 EAL domain CVS48_RS14895 8ad313ab8084a5b918b6a938a0db815b 656 SMART SM00052 407 651 8.9E-10 T 29-03-2018 IPR001633 EAL domain CVS48_RS14895 8ad313ab8084a5b918b6a938a0db815b 656 SUPERFAMILY SSF55073 241 395 4.0E-17 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS20060 87c672bbab51e5e2094ed14aeecc7218 249 SUPERFAMILY SSF46689 19 90 1.39E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS20060 87c672bbab51e5e2094ed14aeecc7218 249 Gene3D G3DSA:1.10.357.10 69 238 4.2E-22 T 29-03-2018 CVS48_RS20060 87c672bbab51e5e2094ed14aeecc7218 249 Gene3D G3DSA:1.10.10.60 4 68 9.9E-20 T 29-03-2018 CVS48_RS20060 87c672bbab51e5e2094ed14aeecc7218 249 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 6.4E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20060 87c672bbab51e5e2094ed14aeecc7218 249 SUPERFAMILY SSF48498 117 236 2.09E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS20060 87c672bbab51e5e2094ed14aeecc7218 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 3.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20060 87c672bbab51e5e2094ed14aeecc7218 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 3.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS08955 63dc7543c0ffc5a39654e477b6f52013 588 Gene3D G3DSA:1.10.3470.10 1 301 1.9E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS08955 63dc7543c0ffc5a39654e477b6f52013 588 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 288 2.4E-38 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS08955 63dc7543c0ffc5a39654e477b6f52013 588 SMART SM00382 363 562 1.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08955 63dc7543c0ffc5a39654e477b6f52013 588 Gene3D G3DSA:3.40.50.300 333 586 1.4E-50 T 29-03-2018 CVS48_RS08955 63dc7543c0ffc5a39654e477b6f52013 588 SUPERFAMILY SSF52540 338 584 1.71E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08955 63dc7543c0ffc5a39654e477b6f52013 588 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 564 585 3.0E-8 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS08955 63dc7543c0ffc5a39654e477b6f52013 588 Pfam PF00005 ABC transporter 355 514 5.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS08610 90129a214a2f1fa7898fab118cf2d02b 414 SUPERFAMILY SSF53822 26 398 1.98E-87 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS08610 90129a214a2f1fa7898fab118cf2d02b 414 Gene3D G3DSA:3.40.50.2300 164 305 1.8E-29 T 29-03-2018 CVS48_RS08610 90129a214a2f1fa7898fab118cf2d02b 414 Gene3D G3DSA:3.40.50.2300 17 163 3.6E-20 T 29-03-2018 CVS48_RS08610 90129a214a2f1fa7898fab118cf2d02b 414 Pfam PF13458 Periplasmic binding protein 26 364 7.7E-89 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS12955 7168f68cff74bfcc9a0b259d8bdf9a0e 296 Pfam PF00571 CBS domain 142 191 5.3E-4 T 29-03-2018 IPR000644 CBS domain CVS48_RS12955 7168f68cff74bfcc9a0b259d8bdf9a0e 296 Pfam PF00571 CBS domain 96 131 0.0014 T 29-03-2018 IPR000644 CBS domain CVS48_RS12955 7168f68cff74bfcc9a0b259d8bdf9a0e 296 SMART SM01091 207 285 1.4E-24 T 29-03-2018 IPR005170 Transporter-associated domain CVS48_RS12955 7168f68cff74bfcc9a0b259d8bdf9a0e 296 Gene3D G3DSA:3.10.580.10 52 197 1.4E-32 T 29-03-2018 CVS48_RS12955 7168f68cff74bfcc9a0b259d8bdf9a0e 296 Pfam PF03471 Transporter associated domain 210 284 1.0E-17 T 29-03-2018 IPR005170 Transporter-associated domain CVS48_RS12955 7168f68cff74bfcc9a0b259d8bdf9a0e 296 Gene3D G3DSA:3.30.465.10 198 285 1.2E-24 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS12955 7168f68cff74bfcc9a0b259d8bdf9a0e 296 SUPERFAMILY SSF56176 205 289 1.8E-20 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS12955 7168f68cff74bfcc9a0b259d8bdf9a0e 296 SUPERFAMILY SSF54631 62 202 1.07E-28 T 29-03-2018 CVS48_RS07660 b212f8ded19623902edca780636af32c 497 PIRSF PIRSF002457 4 497 5.2E-132 T 29-03-2018 IPR030676 Citrate carrier CitT-related CVS48_RS07660 b212f8ded19623902edca780636af32c 497 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 36 491 1.1E-72 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CVS48_RS07660 b212f8ded19623902edca780636af32c 497 Pfam PF00939 Sodium:sulfate symporter transmembrane region 21 497 4.5E-127 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CVS48_RS11620 4180d7dada4bfe9d4fcbab2f0f1590b2 774 Gene3D G3DSA:3.90.55.10 14 97 3.7E-10 T 29-03-2018 CVS48_RS11620 4180d7dada4bfe9d4fcbab2f0f1590b2 774 Gene3D G3DSA:3.90.55.10 481 566 6.8E-24 T 29-03-2018 CVS48_RS11620 4180d7dada4bfe9d4fcbab2f0f1590b2 774 SUPERFAMILY SSF53706 33 631 9.03E-146 T 29-03-2018 CVS48_RS11620 4180d7dada4bfe9d4fcbab2f0f1590b2 774 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 669 696 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CVS48_RS11620 4180d7dada4bfe9d4fcbab2f0f1590b2 774 Gene3D G3DSA:3.40.228.10 151 408 1.4E-49 T 29-03-2018 CVS48_RS11620 4180d7dada4bfe9d4fcbab2f0f1590b2 774 SUPERFAMILY SSF50692 619 772 1.2E-38 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CVS48_RS11620 4180d7dada4bfe9d4fcbab2f0f1590b2 774 Pfam PF00384 Molybdopterin oxidoreductase 61 517 6.0E-58 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS11620 4180d7dada4bfe9d4fcbab2f0f1590b2 774 Gene3D G3DSA:2.40.40.20 608 768 1.5E-26 T 29-03-2018 CVS48_RS11620 4180d7dada4bfe9d4fcbab2f0f1590b2 774 Pfam PF01568 Molydopterin dinucleotide binding domain 631 747 1.2E-21 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CVS48_RS26465 f840ce891eda6aa60487c307a32f6dc1 147 SUPERFAMILY SSF55729 10 146 2.48E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS26465 f840ce891eda6aa60487c307a32f6dc1 147 Pfam PF13673 Acetyltransferase (GNAT) domain 52 146 5.2E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS26465 f840ce891eda6aa60487c307a32f6dc1 147 Gene3D G3DSA:3.40.630.30 7 147 7.4E-35 T 29-03-2018 CVS48_RS11045 73cbe45bde632abddaf1590d58b785b6 168 Gene3D G3DSA:1.10.3760.10 52 165 1.5E-36 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CVS48_RS11045 73cbe45bde632abddaf1590d58b785b6 168 SUPERFAMILY SSF101307 16 162 1.23E-34 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CVS48_RS11045 73cbe45bde632abddaf1590d58b785b6 168 Pfam PF04608 Phosphatidylglycerophosphatase A 21 161 5.1E-47 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CVS48_RS11045 73cbe45bde632abddaf1590d58b785b6 168 PIRSF PIRSF006162 11 167 4.4E-38 T 29-03-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 Pfam PF00994 Probable molybdopterin binding domain 174 311 1.3E-28 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 Pfam PF03454 MoeA C-terminal region (domain IV) 327 394 9.6E-12 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 Gene3D G3DSA:2.170.190.11 56 135 8.4E-26 T 29-03-2018 CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 SUPERFAMILY SSF63867 321 400 2.62E-14 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 Gene3D G3DSA:3.90.105.10 21 55 3.3E-10 T 29-03-2018 CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 SMART SM00852 174 312 3.3E-43 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 171 308 3.2E-28 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 Pfam PF03453 MoeA N-terminal region (domain I and II) 4 161 1.1E-41 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 247 281 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 SUPERFAMILY SSF53218 171 316 7.33E-42 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 Gene3D G3DSA:2.40.340.10 326 397 2.4E-13 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 SUPERFAMILY SSF63882 1 170 1.44E-50 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CVS48_RS12850 a3dde0288e845d60ae5fcf6433b51d28 401 Gene3D G3DSA:3.40.980.10 144 319 4.2E-53 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS06265 61d9db687666e55978248249107ecfb8 174 Pfam PF00466 Ribosomal protein L10 4 100 5.3E-22 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CVS48_RS06265 61d9db687666e55978248249107ecfb8 174 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06265 61d9db687666e55978248249107ecfb8 174 SUPERFAMILY SSF160369 3 171 2.48E-53 T 29-03-2018 CVS48_RS06265 61d9db687666e55978248249107ecfb8 174 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 26.37 T 29-03-2018 IPR022973 Ribosomal protein L10 CVS48_RS05240 cbb876de0a609ac0ddf76b682b1005e3 298 Gene3D G3DSA:1.10.10.10 14 123 1.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05240 cbb876de0a609ac0ddf76b682b1005e3 298 Gene3D G3DSA:3.40.50.10490 124 294 4.8E-25 T 29-03-2018 CVS48_RS05240 cbb876de0a609ac0ddf76b682b1005e3 298 SUPERFAMILY SSF46689 17 91 1.51E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05240 cbb876de0a609ac0ddf76b682b1005e3 298 Pfam PF01418 Helix-turn-helix domain, rpiR family 18 83 2.5E-8 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CVS48_RS05240 cbb876de0a609ac0ddf76b682b1005e3 298 Pfam PF01380 SIS domain 154 275 4.8E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CVS48_RS05240 cbb876de0a609ac0ddf76b682b1005e3 298 SUPERFAMILY SSF53697 127 278 1.36E-24 T 29-03-2018 CVS48_RS15675 907d22a00d6c0d2e63ed50b1318c9028 209 Pfam PF13649 Methyltransferase domain 54 143 2.2E-16 T 29-03-2018 CVS48_RS15675 907d22a00d6c0d2e63ed50b1318c9028 209 Gene3D G3DSA:3.40.50.150 14 208 9.0E-32 T 29-03-2018 CVS48_RS15675 907d22a00d6c0d2e63ed50b1318c9028 209 SUPERFAMILY SSF53335 19 205 4.26E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS23255 73bfbdb3e126cf95f2da493a815650b5 155 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 25 153 2.1E-27 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CVS48_RS23255 73bfbdb3e126cf95f2da493a815650b5 155 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 26 153 1.7E-19 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CVS48_RS23255 73bfbdb3e126cf95f2da493a815650b5 155 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 28 129 9.1E-19 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CVS48_RS23255 73bfbdb3e126cf95f2da493a815650b5 155 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 32 136 6.0E-47 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CVS48_RS23255 73bfbdb3e126cf95f2da493a815650b5 155 Gene3D G3DSA:3.90.470.20 22 155 5.6E-29 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CVS48_RS23255 73bfbdb3e126cf95f2da493a815650b5 155 SUPERFAMILY SSF56214 26 152 3.27E-26 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CVS48_RS23255 73bfbdb3e126cf95f2da493a815650b5 155 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 27 153 24.899 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CVS48_RS03805 f9d4e90dc6005f970f0142fd76e6e05e 244 SUPERFAMILY SSF50891 107 236 1.18E-45 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS03805 f9d4e90dc6005f970f0142fd76e6e05e 244 Gene3D G3DSA:2.40.100.10 105 238 5.6E-48 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS03805 f9d4e90dc6005f970f0142fd76e6e05e 244 Gene3D G3DSA:3.30.1360.40 3 99 2.0E-19 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CVS48_RS03805 f9d4e90dc6005f970f0142fd76e6e05e 244 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 21 229 8.5E-55 T 29-03-2018 IPR010016 KipI family CVS48_RS03805 f9d4e90dc6005f970f0142fd76e6e05e 244 SMART SM00796 15 220 4.4E-87 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CVS48_RS03805 f9d4e90dc6005f970f0142fd76e6e05e 244 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 15 220 3.6E-67 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CVS48_RS03805 f9d4e90dc6005f970f0142fd76e6e05e 244 SUPERFAMILY SSF160467 16 111 2.35E-15 T 29-03-2018 CVS48_RS22465 a54a1fc4ab5847715ca0fcf111ebe438 348 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 39 331 5.9E-72 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CVS48_RS22465 a54a1fc4ab5847715ca0fcf111ebe438 348 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 10 346 38.51 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CVS48_RS22465 a54a1fc4ab5847715ca0fcf111ebe438 348 Gene3D G3DSA:3.40.50.300 55 205 4.0E-6 T 29-03-2018 CVS48_RS22465 a54a1fc4ab5847715ca0fcf111ebe438 348 SUPERFAMILY SSF52540 55 203 1.26E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22465 a54a1fc4ab5847715ca0fcf111ebe438 348 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 22 341 8.4E-103 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 Pfam PF03459 TOBE domain 198 260 1.3E-15 T 29-03-2018 IPR005116 Transport-associated OB, type 1 CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 Pfam PF03459 TOBE domain 125 188 6.7E-18 T 29-03-2018 IPR005116 Transport-associated OB, type 1 CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 Gene3D G3DSA:2.40.50.100 122 185 1.3E-21 T 29-03-2018 CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 SUPERFAMILY SSF50331 123 191 2.43E-21 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 PIRSF PIRSF005763 1 264 7.2E-99 T 29-03-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 SUPERFAMILY SSF50331 195 262 1.85E-19 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 84 5.6E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 123 190 1.1E-24 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 195 261 1.2E-18 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 Gene3D G3DSA:2.40.50.100 186 254 9.3E-21 T 29-03-2018 CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 Gene3D G3DSA:1.10.10.10 3 108 6.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23295 23255bd192ad3795ddf6287c40770f92 264 SUPERFAMILY SSF46785 2 104 1.43E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.8E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 Gene3D G3DSA:3.40.190.10 176 266 3.9E-20 T 29-03-2018 CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 Gene3D G3DSA:1.10.10.10 1 83 1.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 Pfam PF03466 LysR substrate binding domain 87 291 9.1E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 SUPERFAMILY SSF46785 1 85 2.92E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 SUPERFAMILY SSF53850 84 291 1.21E-36 T 29-03-2018 CVS48_RS26375 7452e8ffe6d1d15a2a0e0ca7c7dc71c7 302 Gene3D G3DSA:3.40.190.10 87 175 3.4E-19 T 29-03-2018 CVS48_RS08880 5a5a72c8ac9f625986de43338b737818 159 PIRSF PIRSF021700 1 159 1.7E-66 T 29-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CVS48_RS08880 5a5a72c8ac9f625986de43338b737818 159 Gene3D G3DSA:3.10.180.10 1 131 1.0E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS08880 5a5a72c8ac9f625986de43338b737818 159 SUPERFAMILY SSF54593 4 157 4.13E-49 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS08880 5a5a72c8ac9f625986de43338b737818 159 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 119 2.3E-46 T 29-03-2018 IPR028973 PhnB-like CVS48_RS04450 1c7aa764dc91c1707110852b5946cdac 405 Gene3D G3DSA:2.30.40.10 1 73 3.1E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS04450 1c7aa764dc91c1707110852b5946cdac 405 Pfam PF01979 Amidohydrolase family 57 396 7.4E-28 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS04450 1c7aa764dc91c1707110852b5946cdac 405 SUPERFAMILY SSF51338 361 398 6.17E-29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS04450 1c7aa764dc91c1707110852b5946cdac 405 SUPERFAMILY SSF51338 2 60 6.17E-29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS04450 1c7aa764dc91c1707110852b5946cdac 405 TIGRFAM TIGR01224 hutI: imidazolonepropionase 22 397 8.4E-149 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04450 1c7aa764dc91c1707110852b5946cdac 405 SUPERFAMILY SSF51556 60 359 2.17E-90 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS04450 1c7aa764dc91c1707110852b5946cdac 405 Hamap MF_00372 Imidazolonepropionase [hutI]. 2 399 42.413 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04450 1c7aa764dc91c1707110852b5946cdac 405 Gene3D G3DSA:3.20.20.140 74 359 3.4E-64 T 29-03-2018 CVS48_RS09625 28fd85b547f3723ba05ce45909d390fc 450 ProSitePatterns PS00217 Sugar transport proteins signature 2. 116 141 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS09625 28fd85b547f3723ba05ce45909d390fc 450 SUPERFAMILY SSF103473 6 448 3.14E-87 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS09625 28fd85b547f3723ba05ce45909d390fc 450 Gene3D G3DSA:1.20.1250.20 10 213 3.2E-38 T 29-03-2018 CVS48_RS09625 28fd85b547f3723ba05ce45909d390fc 450 Pfam PF00083 Sugar (and other) transporter 52 449 7.0E-42 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS09625 28fd85b547f3723ba05ce45909d390fc 450 Gene3D G3DSA:1.20.1250.20 240 450 9.3E-30 T 29-03-2018 CVS48_RS14885 a9332ff9d08935eef9dfa768a9441b29 239 SMART SM00862 161 237 8.0E-11 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS14885 a9332ff9d08935eef9dfa768a9441b29 239 SUPERFAMILY SSF46894 155 238 1.98E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS14885 a9332ff9d08935eef9dfa768a9441b29 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 237 5.4E-10 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS14885 a9332ff9d08935eef9dfa768a9441b29 239 Gene3D G3DSA:1.10.10.10 132 239 2.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14885 a9332ff9d08935eef9dfa768a9441b29 239 Pfam PF00072 Response regulator receiver domain 12 119 2.0E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS14885 a9332ff9d08935eef9dfa768a9441b29 239 SUPERFAMILY SSF52172 10 133 7.26E-30 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS14885 a9332ff9d08935eef9dfa768a9441b29 239 SMART SM00448 8 119 1.3E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS14885 a9332ff9d08935eef9dfa768a9441b29 239 Gene3D G3DSA:3.40.50.2300 8 131 1.8E-27 T 29-03-2018 CVS48_RS09665 5f55b67778491ac387456a58785d6fb6 205 Pfam PF01799 [2Fe-2S] binding domain 84 156 2.8E-22 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CVS48_RS09665 5f55b67778491ac387456a58785d6fb6 205 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 18 72 1.9E-6 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS09665 5f55b67778491ac387456a58785d6fb6 205 SUPERFAMILY SSF47741 95 164 2.49E-25 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CVS48_RS09665 5f55b67778491ac387456a58785d6fb6 205 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 50 58 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS09665 5f55b67778491ac387456a58785d6fb6 205 Gene3D G3DSA:3.10.20.30 10 85 6.2E-26 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS09665 5f55b67778491ac387456a58785d6fb6 205 SUPERFAMILY SSF54292 12 89 1.11E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS09665 5f55b67778491ac387456a58785d6fb6 205 Gene3D G3DSA:1.10.150.120 86 184 1.6E-27 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CVS48_RS19700 eccac10fc917e627c7ea09a15ee7d425 358 Gene3D G3DSA:2.40.50.140 283 349 5.5E-4 T 29-03-2018 CVS48_RS19700 eccac10fc917e627c7ea09a15ee7d425 358 SUPERFAMILY SSF52540 4 242 1.6E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19700 eccac10fc917e627c7ea09a15ee7d425 358 Gene3D G3DSA:3.40.50.300 1 240 1.5E-76 T 29-03-2018 CVS48_RS19700 eccac10fc917e627c7ea09a15ee7d425 358 SUPERFAMILY SSF50331 252 356 1.4E-8 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS19700 eccac10fc917e627c7ea09a15ee7d425 358 SMART SM00382 28 211 1.5E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19700 eccac10fc917e627c7ea09a15ee7d425 358 Pfam PF00005 ABC transporter 19 161 7.3E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19700 eccac10fc917e627c7ea09a15ee7d425 358 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS19700 eccac10fc917e627c7ea09a15ee7d425 358 Pfam PF08402 TOBE domain 283 355 1.9E-10 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS13900 01fa6877c8d8bf47188c5bfa328defee 258 SUPERFAMILY SSF52540 11 244 1.66E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13900 01fa6877c8d8bf47188c5bfa328defee 258 Pfam PF00005 ABC transporter 28 182 3.5E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13900 01fa6877c8d8bf47188c5bfa328defee 258 SMART SM00382 36 230 7.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13900 01fa6877c8d8bf47188c5bfa328defee 258 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13900 01fa6877c8d8bf47188c5bfa328defee 258 Gene3D G3DSA:3.40.50.300 8 255 8.5E-63 T 29-03-2018 CVS48_RS13900 01fa6877c8d8bf47188c5bfa328defee 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 12 258 3.3E-122 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CVS48_RS23250 3b54d2f6f3f8df317f02e34bfce45826 352 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 248 265 - T 29-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CVS48_RS23250 3b54d2f6f3f8df317f02e34bfce45826 352 SUPERFAMILY SSF51445 14 328 8.63E-86 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS23250 3b54d2f6f3f8df317f02e34bfce45826 352 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 16 306 1.6E-77 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CVS48_RS23250 3b54d2f6f3f8df317f02e34bfce45826 352 Gene3D G3DSA:3.20.20.300 12 348 4.8E-82 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CVS48_RS23250 3b54d2f6f3f8df317f02e34bfce45826 352 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 14 351 52.584 T 29-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CVS48_RS04850 1bcaf76ce3a06d5d82a183556044665d 551 SUPERFAMILY SSF52540 222 536 1.67E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04850 1bcaf76ce3a06d5d82a183556044665d 551 Gene3D G3DSA:3.40.50.300 376 547 6.0E-17 T 29-03-2018 CVS48_RS04850 1bcaf76ce3a06d5d82a183556044665d 551 Pfam PF13245 AAA domain 222 358 3.3E-7 T 29-03-2018 CVS48_RS04850 1bcaf76ce3a06d5d82a183556044665d 551 Gene3D G3DSA:3.40.50.300 209 375 3.6E-19 T 29-03-2018 CVS48_RS04850 1bcaf76ce3a06d5d82a183556044665d 551 Pfam PF13538 UvrD-like helicase C-terminal domain 485 531 1.0E-10 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Pfam PF00009 Elongation factor Tu GTP binding domain 10 288 6.1E-67 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Gene3D G3DSA:3.30.70.240 615 694 6.0E-32 T 29-03-2018 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Pfam PF14492 Elongation Factor G, domain II 409 483 3.7E-35 T 29-03-2018 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 110.356 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 SMART SM00889 485 604 5.7E-76 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Gene3D G3DSA:2.40.30.10 284 404 2.3E-29 T 29-03-2018 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 SUPERFAMILY SSF54980 409 486 5.76E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Pfam PF03144 Elongation factor Tu domain 2 329 395 4.0E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 SUPERFAMILY SSF52540 7 288 7.83E-107 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 SUPERFAMILY SSF50447 310 407 1.13E-35 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 SUPERFAMILY SSF50447 256 281 1.13E-35 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 SUPERFAMILY SSF54211 484 605 6.07E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 SUPERFAMILY SSF54980 609 697 3.36E-31 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 SMART SM00838 606 695 1.9E-54 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 187 1.0E-33 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Pfam PF03764 Elongation factor G, domain IV 484 603 4.7E-48 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Gene3D G3DSA:3.30.230.10 499 614 2.8E-43 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Gene3D G3DSA:3.40.50.300 1 283 7.7E-59 T 29-03-2018 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Gene3D G3DSA:3.30.70.870 405 498 1.8E-38 T 29-03-2018 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 Pfam PF00679 Elongation factor G C-terminus 606 694 5.6E-32 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS02730 b916b50e77972a8fda4ad124b96bf86b 703 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS24050 bb7b7b0c74457162c8a8a8c2537b8618 214 Gene3D G3DSA:1.10.1670.10 157 211 4.1E-13 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CVS48_RS24050 bb7b7b0c74457162c8a8a8c2537b8618 214 SMART SM00478 55 208 8.9E-17 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CVS48_RS24050 bb7b7b0c74457162c8a8a8c2537b8618 214 SUPERFAMILY SSF48150 35 207 9.77E-43 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CVS48_RS24050 bb7b7b0c74457162c8a8a8c2537b8618 214 Gene3D G3DSA:1.10.340.30 43 155 2.1E-24 T 29-03-2018 CVS48_RS24050 bb7b7b0c74457162c8a8a8c2537b8618 214 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 52 177 4.3E-11 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CVS48_RS13285 f13c59935ef599a13a075ddef4c65dbd 196 SUPERFAMILY SSF52540 5 190 5.02E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13285 f13c59935ef599a13a075ddef4c65dbd 196 Hamap MF_00836 Ribose 1,5-bisphosphate phosphokinase PhnN [phnN]. 13 191 34.372 T 29-03-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS13285 f13c59935ef599a13a075ddef4c65dbd 196 SMART SM00072 13 189 2.0E-4 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CVS48_RS13285 f13c59935ef599a13a075ddef4c65dbd 196 TIGRFAM TIGR02322 phosphon_PhnN: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 15 190 7.8E-62 T 29-03-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS13285 f13c59935ef599a13a075ddef4c65dbd 196 Gene3D G3DSA:3.40.50.300 15 194 2.0E-23 T 29-03-2018 CVS48_RS06480 73aee1ddeb00850e9ae44b172634b907 475 Gene3D G3DSA:3.40.605.10 1 266 7.1E-95 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS06480 73aee1ddeb00850e9ae44b172634b907 475 Gene3D G3DSA:3.40.309.10 267 458 1.4E-70 T 29-03-2018 CVS48_RS06480 73aee1ddeb00850e9ae44b172634b907 475 Pfam PF00171 Aldehyde dehydrogenase family 15 471 2.8E-159 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS06480 73aee1ddeb00850e9ae44b172634b907 475 SUPERFAMILY SSF53720 3 473 6.54E-163 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 Pfam PF03466 LysR substrate binding domain 93 291 1.3E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 Gene3D G3DSA:1.10.10.10 5 89 5.3E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 SUPERFAMILY SSF53850 94 298 3.26E-34 T 29-03-2018 CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 Gene3D G3DSA:3.40.190.10 95 182 1.3E-13 T 29-03-2018 CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 SUPERFAMILY SSF46785 6 84 7.14E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 5.7E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 Gene3D G3DSA:3.40.190.10 183 266 5.9E-17 T 29-03-2018 CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19695 0a865cc82ec8b2dde9e718650ea99a43 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS08710 d1241194933a46732640ae85c58c390f 328 PIRSF PIRSF017082 1 328 1.5E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS08710 d1241194933a46732640ae85c58c390f 328 Gene3D G3DSA:3.40.190.10 129 236 1.0E-8 T 29-03-2018 CVS48_RS08710 d1241194933a46732640ae85c58c390f 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 2.0E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS08710 d1241194933a46732640ae85c58c390f 328 SUPERFAMILY SSF53850 118 288 1.01E-10 T 29-03-2018 CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 SMART SM00382 311 482 1.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 SMART SM00382 31 197 6.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 Gene3D G3DSA:3.40.50.300 77 258 9.0E-46 T 29-03-2018 CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 SUPERFAMILY SSF52540 6 200 4.38E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 SUPERFAMILY SSF52540 281 484 1.05E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 Gene3D G3DSA:3.40.50.300 18 76 1.2E-8 T 29-03-2018 CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 Pfam PF00005 ABC transporter 303 436 1.1E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 Pfam PF00005 ABC transporter 22 152 5.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 Pfam PF12848 ABC transporter 191 265 4.7E-9 T 29-03-2018 IPR032781 ABC-transporter extension domain CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 Gene3D G3DSA:3.40.50.300 259 516 4.6E-54 T 29-03-2018 CVS48_RS02520 989dc843e6609f54180b869d70b003f7 608 Pfam PF16326 ABC transporter C-terminal domain 538 601 3.2E-14 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CVS48_RS17495 b15158196ad622f42840decfeca4bc53 376 Pfam PF07690 Major Facilitator Superfamily 2 314 2.8E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS17495 b15158196ad622f42840decfeca4bc53 376 Gene3D G3DSA:1.20.1250.20 184 376 1.7E-21 T 29-03-2018 CVS48_RS17495 b15158196ad622f42840decfeca4bc53 376 Gene3D G3DSA:1.20.1250.20 1 183 4.2E-22 T 29-03-2018 CVS48_RS17495 b15158196ad622f42840decfeca4bc53 376 SUPERFAMILY SSF103473 2 374 1.83E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS12490 a6f4fa0281810538103f774c44b9f3c7 251 PIRSF PIRSF039085 1 247 3.1E-97 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS12490 a6f4fa0281810538103f774c44b9f3c7 251 Gene3D G3DSA:3.40.50.300 1 251 1.3E-67 T 29-03-2018 CVS48_RS12490 a6f4fa0281810538103f774c44b9f3c7 251 SUPERFAMILY SSF52540 1 241 1.98E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS12490 a6f4fa0281810538103f774c44b9f3c7 251 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS12490 a6f4fa0281810538103f774c44b9f3c7 251 SMART SM00382 26 219 2.0E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS12490 a6f4fa0281810538103f774c44b9f3c7 251 Pfam PF00005 ABC transporter 17 171 1.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS20530 aefa73bdadbee700094b6d7b7d789492 409 Gene3D G3DSA:1.10.10.10 330 389 1.9E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20530 aefa73bdadbee700094b6d7b7d789492 409 Gene3D G3DSA:1.10.10.10 203 320 7.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21530 03c527496f7e44caa619379f29b39e4c 308 SUPERFAMILY SSF51197 3 289 2.34E-71 T 29-03-2018 CVS48_RS21530 03c527496f7e44caa619379f29b39e4c 308 Gene3D G3DSA:3.60.130.10 1 293 3.9E-61 T 29-03-2018 CVS48_RS21530 03c527496f7e44caa619379f29b39e4c 308 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 6 282 1.5E-53 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CVS48_RS21130 8c855c59c9e3c10628d1a8ed1f8c4e2e 262 SUPERFAMILY SSF52833 91 185 4.07E-5 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS21130 8c855c59c9e3c10628d1a8ed1f8c4e2e 262 Pfam PF05988 Bacterial protein of unknown function (DUF899) 11 229 2.9E-80 T 29-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like CVS48_RS21130 8c855c59c9e3c10628d1a8ed1f8c4e2e 262 Gene3D G3DSA:3.40.30.10 19 192 2.2E-12 T 29-03-2018 CVS48_RS05415 7f2b659375c9f545816ef48b9be37f78 265 Gene3D G3DSA:3.60.21.10 1 256 4.9E-41 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS05415 7f2b659375c9f545816ef48b9be37f78 265 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 255 37.776 T 29-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CVS48_RS05415 7f2b659375c9f545816ef48b9be37f78 265 Pfam PF00149 Calcineurin-like phosphoesterase 2 198 7.1E-17 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS05415 7f2b659375c9f545816ef48b9be37f78 265 SUPERFAMILY SSF56300 1 255 1.98E-56 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS00050 6f6e66beb04f24d606458190ee8838c4 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.037 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS00050 6f6e66beb04f24d606458190ee8838c4 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 9.0E-39 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS00050 6f6e66beb04f24d606458190ee8838c4 89 SUPERFAMILY SSF47060 4 89 2.94E-35 T 29-03-2018 IPR009068 S15/NS1, RNA-binding CVS48_RS00050 6f6e66beb04f24d606458190ee8838c4 89 SMART SM01387 8 88 1.2E-52 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS00050 6f6e66beb04f24d606458190ee8838c4 89 Pfam PF00312 Ribosomal protein S15 8 88 9.0E-38 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS00050 6f6e66beb04f24d606458190ee8838c4 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS00050 6f6e66beb04f24d606458190ee8838c4 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-31 T 29-03-2018 CVS48_RS00050 6f6e66beb04f24d606458190ee8838c4 89 Gene3D G3DSA:1.10.287.10 2 89 3.2E-35 T 29-03-2018 CVS48_RS29105 6f6e66beb04f24d606458190ee8838c4 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.037 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS29105 6f6e66beb04f24d606458190ee8838c4 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 9.0E-39 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS29105 6f6e66beb04f24d606458190ee8838c4 89 SUPERFAMILY SSF47060 4 89 2.94E-35 T 29-03-2018 IPR009068 S15/NS1, RNA-binding CVS48_RS29105 6f6e66beb04f24d606458190ee8838c4 89 SMART SM01387 8 88 1.2E-52 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS29105 6f6e66beb04f24d606458190ee8838c4 89 Pfam PF00312 Ribosomal protein S15 8 88 9.0E-38 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS29105 6f6e66beb04f24d606458190ee8838c4 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS29105 6f6e66beb04f24d606458190ee8838c4 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-31 T 29-03-2018 CVS48_RS29105 6f6e66beb04f24d606458190ee8838c4 89 Gene3D G3DSA:1.10.287.10 2 89 3.2E-35 T 29-03-2018 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 38 430 8.8E-159 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 1.6E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 1.6E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 1.6E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 1.6E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 1.6E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 PRINTS PR00083 Histidinol dehydrogenase signature 324 349 1.6E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 PRINTS PR00083 Histidinol dehydrogenase signature 365 383 1.6E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 1.6E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 PIRSF PIRSF000099 4 433 7.6E-157 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 431 40.311 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 SUPERFAMILY SSF53720 25 431 1.35E-86 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 Gene3D G3DSA:3.40.50.1980 29 229 1.4E-85 T 29-03-2018 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 Pfam PF00815 Histidinol dehydrogenase 27 430 2.0E-165 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS05100 cac345fa5c8bc1378aaa657d0f2d3cc8 434 Gene3D G3DSA:3.40.50.1980 230 375 6.6E-67 T 29-03-2018 CVS48_RS11140 2614de001c579ca6e23937f2052fdd8d 333 SUPERFAMILY SSF51556 4 331 2.54E-75 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS11140 2614de001c579ca6e23937f2052fdd8d 333 Gene3D G3DSA:3.20.20.140 2 332 8.6E-64 T 29-03-2018 CVS48_RS11140 2614de001c579ca6e23937f2052fdd8d 333 Pfam PF04909 Amidohydrolase 5 331 5.8E-47 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS00350 2b4874411fb627354d67e525fbef9b89 418 SMART SM01329 30 414 1.9E-164 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CVS48_RS00350 2b4874411fb627354d67e525fbef9b89 418 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 412 1.2E-112 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CVS48_RS00350 2b4874411fb627354d67e525fbef9b89 418 SUPERFAMILY SSF53659 4 418 9.41E-141 T 29-03-2018 CVS48_RS00350 2b4874411fb627354d67e525fbef9b89 418 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 305 324 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CVS48_RS00350 2b4874411fb627354d67e525fbef9b89 418 Gene3D G3DSA:3.40.718.10 19 418 7.3E-126 T 29-03-2018 CVS48_RS00350 2b4874411fb627354d67e525fbef9b89 418 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 418 4.0E-217 T 29-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 SUPERFAMILY SSF46785 20 131 4.34E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 Gene3D G3DSA:1.10.10.10 13 102 7.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 Gene3D G3DSA:3.40.190.10 112 196 1.5E-10 T 29-03-2018 CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 SUPERFAMILY SSF53850 109 317 4.34E-27 T 29-03-2018 CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 Pfam PF03466 LysR substrate binding domain 107 316 2.5E-25 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 56 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 56 67 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 46 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 Gene3D G3DSA:3.40.190.10 197 285 5.9E-19 T 29-03-2018 CVS48_RS15915 7c43a00fcde5bfa76ac9760fcf4e5501 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 80 5.0E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18305 50209f20031b041b3f85f4fae28be2a4 321 Gene3D G3DSA:3.40.50.1820 9 321 1.3E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS18305 50209f20031b041b3f85f4fae28be2a4 321 Pfam PF07859 alpha/beta hydrolase fold 90 295 2.8E-50 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CVS48_RS18305 50209f20031b041b3f85f4fae28be2a4 321 SUPERFAMILY SSF53474 40 319 4.61E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS17360 9730dc61f6d38e76773fa58baf029bec 91 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 62 4.9E-6 T 29-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CVS48_RS17360 9730dc61f6d38e76773fa58baf029bec 91 Gene3D G3DSA:3.30.390.50 1 88 9.4E-28 T 29-03-2018 CVS48_RS17360 9730dc61f6d38e76773fa58baf029bec 91 SUPERFAMILY SSF82649 4 58 2.56E-5 T 29-03-2018 CVS48_RS05695 e28a2e4d6b9bec62d858306968020645 379 SUPERFAMILY SSF51419 31 264 2.47E-38 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS05695 e28a2e4d6b9bec62d858306968020645 379 Pfam PF01168 Alanine racemase, N-terminal domain 32 257 2.1E-26 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS05695 e28a2e4d6b9bec62d858306968020645 379 SMART SM01119 274 362 4.0E-34 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CVS48_RS05695 e28a2e4d6b9bec62d858306968020645 379 Pfam PF14031 Putative serine dehydratase domain 274 361 3.8E-21 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CVS48_RS05695 e28a2e4d6b9bec62d858306968020645 379 Gene3D G3DSA:3.20.20.10 16 266 9.1E-44 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS08465 c184dae79280259e1250442299ab0bd9 697 SUPERFAMILY SSF109604 206 269 3.38E-7 T 29-03-2018 CVS48_RS08465 c184dae79280259e1250442299ab0bd9 697 SUPERFAMILY SSF109604 106 168 3.38E-7 T 29-03-2018 CVS48_RS08465 c184dae79280259e1250442299ab0bd9 697 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 565 689 1.3E-26 T 29-03-2018 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal CVS48_RS08465 c184dae79280259e1250442299ab0bd9 697 Gene3D G3DSA:1.10.3210.10 50 298 3.5E-9 T 29-03-2018 CVS48_RS08465 c184dae79280259e1250442299ab0bd9 697 SUPERFAMILY SSF46785 566 687 2.99E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08465 c184dae79280259e1250442299ab0bd9 697 SMART SM00471 112 279 0.005 T 29-03-2018 IPR003607 HD/PDEase domain CVS48_RS08465 c184dae79280259e1250442299ab0bd9 697 Pfam PF07514 Putative helicase 55 376 2.6E-78 T 29-03-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative CVS48_RS08465 c184dae79280259e1250442299ab0bd9 697 Gene3D G3DSA:2.40.10.200 582 689 3.7E-12 T 29-03-2018 CVS48_RS13170 807eec7cc66ceca63ac1d6e80b6bebbf 833 Pfam PF11339 Protein of unknown function (DUF3141) 26 603 1.9E-292 T 29-03-2018 IPR024501 Protein of unknown function DUF3141 CVS48_RS13170 807eec7cc66ceca63ac1d6e80b6bebbf 833 SUPERFAMILY SSF53474 56 380 1.15E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS13170 807eec7cc66ceca63ac1d6e80b6bebbf 833 Gene3D G3DSA:3.40.50.1820 34 394 8.1E-14 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS09490 7e3190691395998da2964b7266e22072 359 Pfam PF08402 TOBE domain 282 356 9.8E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS09490 7e3190691395998da2964b7266e22072 359 Gene3D G3DSA:3.40.50.300 1 243 2.3E-71 T 29-03-2018 CVS48_RS09490 7e3190691395998da2964b7266e22072 359 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS09490 7e3190691395998da2964b7266e22072 359 SUPERFAMILY SSF52540 6 244 1.82E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09490 7e3190691395998da2964b7266e22072 359 Gene3D G3DSA:2.40.50.100 244 300 0.0033 T 29-03-2018 CVS48_RS09490 7e3190691395998da2964b7266e22072 359 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 36 295 6.7E-109 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CVS48_RS09490 7e3190691395998da2964b7266e22072 359 SUPERFAMILY SSF50331 238 355 4.76E-14 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS09490 7e3190691395998da2964b7266e22072 359 Pfam PF00005 ABC transporter 24 163 8.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS09490 7e3190691395998da2964b7266e22072 359 SMART SM00382 30 213 1.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS11025 8cf85e5d4bab07ae6214fe9f6c1c0ed5 392 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 23 213 6.3E-81 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS11025 8cf85e5d4bab07ae6214fe9f6c1c0ed5 392 SUPERFAMILY SSF55821 16 218 2.04E-84 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CVS48_RS11025 8cf85e5d4bab07ae6214fe9f6c1c0ed5 392 Pfam PF00925 GTP cyclohydrolase II 225 380 1.7E-31 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CVS48_RS11025 8cf85e5d4bab07ae6214fe9f6c1c0ed5 392 SUPERFAMILY SSF142695 219 381 1.83E-41 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CVS48_RS11025 8cf85e5d4bab07ae6214fe9f6c1c0ed5 392 Gene3D G3DSA:3.90.870.10 9 227 2.5E-93 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CVS48_RS11025 8cf85e5d4bab07ae6214fe9f6c1c0ed5 392 PIRSF PIRSF001259 17 390 3.1E-111 T 29-03-2018 CVS48_RS11025 8cf85e5d4bab07ae6214fe9f6c1c0ed5 392 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 19 214 4.1E-72 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS11025 8cf85e5d4bab07ae6214fe9f6c1c0ed5 392 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 16 218 38.05 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1284 1319 1.3E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1172 1210 0.21 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1150 1190 0.02 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1467 1507 5.8E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1243 1275 0.69 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1528 1564 2.1 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 497 529 0.075 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1508 1526 0.39 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 450 467 2.8 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2197 2236 0.027 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1396 1427 2.9E-5 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1877 1913 3.9E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1592 1622 1.7 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2217 2255 0.025 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1340 1379 1.8E-7 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1309 1339 0.0012 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 2100 2359 2.3E-6 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05860 haemagglutination activity domain 43 162 1.1E-31 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 SUPERFAMILY SSF51126 45 290 2.13E-59 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF13332 Haemagluttinin repeat 2296 2340 1.1E-4 T 29-03-2018 IPR025157 Hemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF13332 Haemagluttinin repeat 2350 2415 1.2E-6 T 29-03-2018 IPR025157 Hemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF13332 Haemagluttinin repeat 353 490 9.6E-4 T 29-03-2018 IPR025157 Hemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF13332 Haemagluttinin repeat 2426 2577 3.6E-13 T 29-03-2018 IPR025157 Hemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF13332 Haemagluttinin repeat 2653 2826 8.2E-39 T 29-03-2018 IPR025157 Hemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 64 160 3.7E-21 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 SMART SM00912 45 165 1.2E-39 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 1068 1126 6.8 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 608 671 0.51 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 539 606 17.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 2195 2255 0.26 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 879 936 10.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 1272 1318 0.13 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 1877 1908 84.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 959 1014 1.1 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 212 285 0.0022 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 1133 1198 1.5E-4 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 1398 1457 4.6E-5 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 1514 1599 200.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Pfam PF05594 Haemagluttinin repeat 1465 1512 0.061 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 32 326 2.3E-60 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 1078 1206 1.0E-5 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 1388 1525 2.4E-9 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 1846 1936 0.069 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 327 402 0.18 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 687 797 0.048 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 1526 1581 0.013 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 938 1018 0.002 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 1216 1387 1.5E-7 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 560 686 6.5E-5 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 488 551 0.023 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS21450 295600a95120fe2d4eb8af8688e6d47d 3529 Gene3D G3DSA:2.160.20.10 798 937 0.0088 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS03620 317ae82720f5a75f128e8b3b5d8076e6 276 SUPERFAMILY SSF47413 44 92 1.39E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS03620 317ae82720f5a75f128e8b3b5d8076e6 276 Gene3D G3DSA:1.10.260.40 13 114 1.1E-14 T 29-03-2018 CVS48_RS03620 317ae82720f5a75f128e8b3b5d8076e6 276 Pfam PF13560 Helix-turn-helix domain 20 99 2.0E-16 T 29-03-2018 CVS48_RS03620 317ae82720f5a75f128e8b3b5d8076e6 276 SMART SM00530 24 96 5.5E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 6 292 39.361 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 Gene3D G3DSA:3.20.20.70 1 299 1.4E-83 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 7.8E-16 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 7.8E-16 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 7.8E-16 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 7.8E-16 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 SUPERFAMILY SSF51569 3 290 1.67E-83 T 29-03-2018 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 SMART SM01130 6 294 1.3E-93 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 Pfam PF00701 Dihydrodipicolinate synthetase family 7 288 3.2E-68 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 PIRSF PIRSF001365 3 299 6.4E-76 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09480 940dc0fcfaac9b3084a8a94be6ac2822 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 10 289 5.4E-67 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 SUPERFAMILY SSF53254 1 245 1.06E-79 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.595 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 SMART SM00855 3 189 8.2E-30 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 PIRSF PIRSF000709 135 221 0.051 T 29-03-2018 CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 PIRSF PIRSF000709 2 111 3.3E-8 T 29-03-2018 CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 Gene3D G3DSA:3.40.50.1240 1 248 4.4E-69 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 2 246 1.1E-118 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 123 1.1E-30 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 128 219 2.7E-6 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CVS48_RS08015 da8057036bc4d71c996bcf7a3d94d3a3 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 Gene3D G3DSA:3.40.190.10 88 177 2.6E-14 T 29-03-2018 CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 SUPERFAMILY SSF53850 89 286 8.69E-34 T 29-03-2018 CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 Gene3D G3DSA:1.10.10.10 1 84 3.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 Pfam PF03466 LysR substrate binding domain 88 274 5.2E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.9E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 Gene3D G3DSA:3.40.190.10 178 258 7.5E-10 T 29-03-2018 CVS48_RS03300 210a13dcd6a37922bdd8f164baf3ef89 296 SUPERFAMILY SSF46785 1 110 1.14E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07475 2a10fa2c2095396d83eaf185bc36e387 253 Pfam PF03167 Uracil DNA glycosylase superfamily 64 227 3.1E-23 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS07475 2a10fa2c2095396d83eaf185bc36e387 253 SMART SM00986 63 228 4.8E-33 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS07475 2a10fa2c2095396d83eaf185bc36e387 253 SMART SM00987 63 228 4.8E-33 T 29-03-2018 CVS48_RS07475 2a10fa2c2095396d83eaf185bc36e387 253 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 71 80 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS07475 2a10fa2c2095396d83eaf185bc36e387 253 SUPERFAMILY SSF52141 19 240 9.38E-75 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS07475 2a10fa2c2095396d83eaf185bc36e387 253 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 20 239 34.514 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS07475 2a10fa2c2095396d83eaf185bc36e387 253 Gene3D G3DSA:3.40.470.10 3 241 2.5E-82 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS07475 2a10fa2c2095396d83eaf185bc36e387 253 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 22 232 4.6E-69 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS16555 74140657d0602aa5c1ff376a066df9aa 474 SUPERFAMILY SSF56425 268 404 3.66E-22 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS16555 74140657d0602aa5c1ff376a066df9aa 474 Gene3D G3DSA:3.50.50.60 311 463 3.0E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16555 74140657d0602aa5c1ff376a066df9aa 474 Gene3D G3DSA:3.50.50.60 2 309 1.1E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16555 74140657d0602aa5c1ff376a066df9aa 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 451 466 8.8E-6 T 29-03-2018 CVS48_RS16555 74140657d0602aa5c1ff376a066df9aa 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 8.8E-6 T 29-03-2018 CVS48_RS16555 74140657d0602aa5c1ff376a066df9aa 474 Pfam PF00890 FAD binding domain 6 436 3.0E-50 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS16555 74140657d0602aa5c1ff376a066df9aa 474 SUPERFAMILY SSF51905 2 271 2.18E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16555 74140657d0602aa5c1ff376a066df9aa 474 SUPERFAMILY SSF51905 403 464 2.18E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS25930 875cbd933b4ea803966f072eaace71df 428 Pfam PF02353 Mycolic acid cyclopropane synthetase 110 387 2.1E-94 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS25930 875cbd933b4ea803966f072eaace71df 428 PIRSF PIRSF003085 4 413 1.2E-129 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CVS48_RS25930 875cbd933b4ea803966f072eaace71df 428 Gene3D G3DSA:3.40.50.150 107 391 8.3E-59 T 29-03-2018 CVS48_RS25930 875cbd933b4ea803966f072eaace71df 428 SUPERFAMILY SSF53335 121 391 1.34E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS18890 888a90694305e2d59988ac86304f1750 161 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CVS48_RS18890 888a90694305e2d59988ac86304f1750 161 SMART SM00347 43 146 1.4E-26 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS18890 888a90694305e2d59988ac86304f1750 161 Gene3D G3DSA:1.10.10.10 1 161 8.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18890 888a90694305e2d59988ac86304f1750 161 SUPERFAMILY SSF46785 10 160 1.87E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18890 888a90694305e2d59988ac86304f1750 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 5.2E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS18890 888a90694305e2d59988ac86304f1750 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 5.2E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS18890 888a90694305e2d59988ac86304f1750 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 5.2E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS18890 888a90694305e2d59988ac86304f1750 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 5.2E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS18890 888a90694305e2d59988ac86304f1750 161 Pfam PF12802 MarR family 49 110 1.2E-13 T 29-03-2018 CVS48_RS07740 732def65cf68603e5a545507680addf8 308 Pfam PF02603 HPr Serine kinase N terminus 3 127 2.3E-23 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CVS48_RS07740 732def65cf68603e5a545507680addf8 308 Gene3D G3DSA:3.40.50.300 133 290 9.3E-42 T 29-03-2018 CVS48_RS07740 732def65cf68603e5a545507680addf8 308 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 1 306 37.481 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CVS48_RS07740 732def65cf68603e5a545507680addf8 308 SUPERFAMILY SSF53795 132 298 1.95E-35 T 29-03-2018 CVS48_RS07740 732def65cf68603e5a545507680addf8 308 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 3 301 8.8E-99 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CVS48_RS07740 732def65cf68603e5a545507680addf8 308 Gene3D G3DSA:3.40.1390.20 1 132 2.2E-29 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CVS48_RS07740 732def65cf68603e5a545507680addf8 308 SUPERFAMILY SSF75138 7 131 1.7E-29 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CVS48_RS07740 732def65cf68603e5a545507680addf8 308 Pfam PF07475 HPr Serine kinase C-terminal domain 129 299 1.5E-64 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CVS48_RS16780 acbe856edab8aeb8fa3f27389abd7690 329 SUPERFAMILY SSF103088 159 270 5.36E-19 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS16780 acbe856edab8aeb8fa3f27389abd7690 329 Gene3D G3DSA:3.30.1330.60 113 312 1.7E-35 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS16780 acbe856edab8aeb8fa3f27389abd7690 329 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 13 65 7.9E-19 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CVS48_RS16780 acbe856edab8aeb8fa3f27389abd7690 329 Pfam PF00691 OmpA family 166 254 1.5E-10 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 Pfam PF03466 LysR substrate binding domain 81 281 2.7E-22 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 Gene3D G3DSA:3.40.190.10 172 253 4.8E-16 T 29-03-2018 CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 56 1.0E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 8.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 8.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 8.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 SUPERFAMILY SSF46785 1 76 8.16E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 Gene3D G3DSA:3.40.190.10 78 171 6.3E-10 T 29-03-2018 CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 Gene3D G3DSA:1.10.10.10 1 77 8.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09615 8ad1138a34f1d6a2cfe25f613e2cef78 314 SUPERFAMILY SSF53850 80 284 2.17E-26 T 29-03-2018 CVS48_RS09570 d353865b1d94dc13107b0c7d2f6bee5e 495 Pfam PF06863 Protein of unknown function (DUF1254) 101 232 3.5E-45 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 CVS48_RS09570 d353865b1d94dc13107b0c7d2f6bee5e 495 SUPERFAMILY SSF160935 58 493 9.29E-128 T 29-03-2018 CVS48_RS09570 d353865b1d94dc13107b0c7d2f6bee5e 495 Gene3D G3DSA:2.60.120.600 324 495 9.6E-53 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 CVS48_RS09570 d353865b1d94dc13107b0c7d2f6bee5e 495 Gene3D G3DSA:2.60.40.1610 101 250 1.1E-48 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 CVS48_RS09570 d353865b1d94dc13107b0c7d2f6bee5e 495 Pfam PF06742 Protein of unknown function (DUF1214) 367 477 2.0E-34 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 SUPERFAMILY SSF52518 338 543 4.32E-63 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 ProSitePatterns PS00801 Transketolase signature 1. 16 36 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 SMART SM00861 359 542 3.3E-67 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 Gene3D G3DSA:3.40.50.970 366 554 4.6E-41 T 29-03-2018 CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 Gene3D G3DSA:3.40.50.970 4 365 1.7E-121 T 29-03-2018 CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 Pfam PF02780 Transketolase, C-terminal domain 557 670 6.5E-18 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 Gene3D G3DSA:3.40.50.920 555 677 1.5E-35 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 Pfam PF02779 Transketolase, pyrimidine binding domain 358 541 8.9E-45 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 SUPERFAMILY SSF52518 10 323 5.65E-119 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 11 338 2.5E-161 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 TIGRFAM TIGR00232 tktlase_bact: transketolase 12 677 1.6E-284 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CVS48_RS13130 3a7eb7743cf12eff236f54dc933af14f 678 SUPERFAMILY SSF52922 551 678 2.49E-44 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 SUPERFAMILY SSF46689 425 498 3.58E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 SMART SM00448 2 113 5.4E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 Gene3D G3DSA:1.10.8.60 315 386 3.9E-22 T 29-03-2018 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 Pfam PF02954 Bacterial regulatory protein, Fis family 456 495 2.9E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 Gene3D G3DSA:1.10.10.60 387 498 7.5E-23 T 29-03-2018 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 396 6.6E-186 T 29-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 SUPERFAMILY SSF52172 2 185 2.42E-39 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 Pfam PF00158 Sigma-54 interaction domain 145 308 1.5E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 Gene3D G3DSA:3.40.50.2300 2 147 1.0E-30 T 29-03-2018 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 Pfam PF00072 Response regulator receiver domain 4 113 8.6E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 SUPERFAMILY SSF52540 146 385 5.7E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 478 498 1.4E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 461 478 1.4E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 Gene3D G3DSA:3.40.50.300 148 314 1.1E-27 T 29-03-2018 CVS48_RS19470 7223755007a38ac59f5726e50b51e2c4 500 SMART SM00382 162 305 8.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS06120 892b9a3e01958a7eaaeff33cabe3b73e 332 PIRSF PIRSF017082 1 332 1.2E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS06120 892b9a3e01958a7eaaeff33cabe3b73e 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 114 323 4.6E-19 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS06120 892b9a3e01958a7eaaeff33cabe3b73e 332 SUPERFAMILY SSF53850 100 236 5.18E-9 T 29-03-2018 CVS48_RS06120 892b9a3e01958a7eaaeff33cabe3b73e 332 Gene3D G3DSA:3.40.190.10 127 258 1.3E-13 T 29-03-2018 CVS48_RS25385 128421869a55f5ee0cc0984bd5f1c6d5 489 Pfam PF01979 Amidohydrolase family 51 441 7.0E-23 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS25385 128421869a55f5ee0cc0984bd5f1c6d5 489 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 8 460 1.1E-160 T 29-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CVS48_RS25385 128421869a55f5ee0cc0984bd5f1c6d5 489 SUPERFAMILY SSF51338 5 63 9.15E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25385 128421869a55f5ee0cc0984bd5f1c6d5 489 SUPERFAMILY SSF51556 55 388 2.64E-93 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS25385 128421869a55f5ee0cc0984bd5f1c6d5 489 SUPERFAMILY SSF51338 356 460 3.87E-37 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25385 128421869a55f5ee0cc0984bd5f1c6d5 489 Gene3D G3DSA:3.20.20.140 282 429 4.2E-44 T 29-03-2018 CVS48_RS25385 128421869a55f5ee0cc0984bd5f1c6d5 489 Gene3D G3DSA:3.20.20.140 69 281 4.8E-51 T 29-03-2018 CVS48_RS25385 128421869a55f5ee0cc0984bd5f1c6d5 489 Gene3D G3DSA:2.30.40.10 2 68 1.5E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS12660 59a8b266d245a95a383d089efd3c4515 621 Gene3D G3DSA:3.10.490.10 477 613 1.4E-29 T 29-03-2018 CVS48_RS12660 59a8b266d245a95a383d089efd3c4515 621 SUPERFAMILY SSF75304 11 458 4.32E-112 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS12660 59a8b266d245a95a383d089efd3c4515 621 Gene3D G3DSA:3.90.1300.10 8 464 1.8E-111 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS12660 59a8b266d245a95a383d089efd3c4515 621 Pfam PF01425 Amidase 77 446 3.5E-86 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS12660 59a8b266d245a95a383d089efd3c4515 621 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 46 604 3.3E-255 T 29-03-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 CVS48_RS17970 0eb09c51529098992d6a6f089aa75819 310 SUPERFAMILY SSF51735 6 139 4.85E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS17970 0eb09c51529098992d6a6f089aa75819 310 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 4 306 5.6E-119 T 29-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS17970 0eb09c51529098992d6a6f089aa75819 310 SMART SM00859 5 106 2.7E-9 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CVS48_RS17970 0eb09c51529098992d6a6f089aa75819 310 Gene3D G3DSA:3.40.50.720 9 125 5.8E-18 T 29-03-2018 CVS48_RS17970 0eb09c51529098992d6a6f089aa75819 310 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 308 51.199 T 29-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS17970 0eb09c51529098992d6a6f089aa75819 310 SUPERFAMILY SSF55347 117 289 2.35E-36 T 29-03-2018 CVS48_RS17970 0eb09c51529098992d6a6f089aa75819 310 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 112 128 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS17970 0eb09c51529098992d6a6f089aa75819 310 Gene3D G3DSA:3.30.360.10 126 289 2.9E-45 T 29-03-2018 CVS48_RS17970 0eb09c51529098992d6a6f089aa75819 310 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 45 100 5.7E-9 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CVS48_RS20055 ab5e66a2470836afc89520b1c95eb8b8 345 Pfam PF00107 Zinc-binding dehydrogenase 161 300 5.5E-21 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS20055 ab5e66a2470836afc89520b1c95eb8b8 345 Gene3D G3DSA:3.90.180.10 2 151 1.1E-33 T 29-03-2018 CVS48_RS20055 ab5e66a2470836afc89520b1c95eb8b8 345 SMART SM00829 22 339 8.8E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS20055 ab5e66a2470836afc89520b1c95eb8b8 345 Gene3D G3DSA:3.40.50.720 152 282 3.9E-30 T 29-03-2018 CVS48_RS20055 ab5e66a2470836afc89520b1c95eb8b8 345 SUPERFAMILY SSF50129 7 146 1.41E-43 T 29-03-2018 IPR011032 GroES-like CVS48_RS20055 ab5e66a2470836afc89520b1c95eb8b8 345 SUPERFAMILY SSF51735 127 302 5.34E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS20055 ab5e66a2470836afc89520b1c95eb8b8 345 Pfam PF16884 N-terminal domain of oxidoreductase 9 114 8.1E-43 T 29-03-2018 CVS48_RS16640 4df8b5d11094373212b823e86f3e8c14 494 Gene3D G3DSA:1.20.1600.10 20 481 6.6E-108 T 29-03-2018 CVS48_RS16640 4df8b5d11094373212b823e86f3e8c14 494 SUPERFAMILY SSF56954 2 32 9.81E-117 T 29-03-2018 CVS48_RS16640 4df8b5d11094373212b823e86f3e8c14 494 SUPERFAMILY SSF56954 61 478 9.81E-117 T 29-03-2018 CVS48_RS16640 4df8b5d11094373212b823e86f3e8c14 494 Pfam PF02321 Outer membrane efflux protein 70 260 9.5E-29 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS16640 4df8b5d11094373212b823e86f3e8c14 494 Pfam PF02321 Outer membrane efflux protein 293 473 2.3E-29 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS16640 4df8b5d11094373212b823e86f3e8c14 494 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 475 4.9E-134 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS02800 2f7132a7f183fef39629bb96ff5c60c7 402 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 2 397 21.233 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CVS48_RS02800 2f7132a7f183fef39629bb96ff5c60c7 402 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 4 397 2.4E-117 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CVS48_RS02800 2f7132a7f183fef39629bb96ff5c60c7 402 Pfam PF03616 Sodium/glutamate symporter 3 366 2.6E-111 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CVS48_RS24910 cad0f1d9f7741d0d0c48d78870b75268 324 SUPERFAMILY SSF53850 113 281 1.09E-12 T 29-03-2018 CVS48_RS24910 cad0f1d9f7741d0d0c48d78870b75268 324 Gene3D G3DSA:3.40.190.10 122 232 1.2E-8 T 29-03-2018 CVS48_RS24910 cad0f1d9f7741d0d0c48d78870b75268 324 PIRSF PIRSF017082 1 323 1.2E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS24910 cad0f1d9f7741d0d0c48d78870b75268 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 1.4E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04610 052393870c934154211087df54de61e6 304 SUPERFAMILY SSF53850 90 295 2.33E-40 T 29-03-2018 CVS48_RS04610 052393870c934154211087df54de61e6 304 Pfam PF03466 LysR substrate binding domain 89 292 4.7E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS04610 052393870c934154211087df54de61e6 304 Gene3D G3DSA:3.40.190.10 93 177 7.5E-18 T 29-03-2018 CVS48_RS04610 052393870c934154211087df54de61e6 304 Gene3D G3DSA:3.40.190.10 178 263 1.4E-20 T 29-03-2018 CVS48_RS04610 052393870c934154211087df54de61e6 304 Gene3D G3DSA:1.10.10.10 1 85 5.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04610 052393870c934154211087df54de61e6 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 7.2E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04610 052393870c934154211087df54de61e6 304 SUPERFAMILY SSF46785 4 112 1.61E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 3 348 3.0E-75 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 PRINTS PR01005 Flagellar hook-associated protein signature 10 33 1.4E-42 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 PRINTS PR01005 Flagellar hook-associated protein signature 449 468 1.4E-42 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 PRINTS PR01005 Flagellar hook-associated protein signature 522 546 1.4E-42 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 PRINTS PR01005 Flagellar hook-associated protein signature 155 179 1.4E-42 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 PRINTS PR01005 Flagellar hook-associated protein signature 475 496 1.4E-42 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 PRINTS PR01005 Flagellar hook-associated protein signature 122 142 1.4E-42 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 PRINTS PR01005 Flagellar hook-associated protein signature 48 70 1.4E-42 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 PRINTS PR01005 Flagellar hook-associated protein signature 363 385 1.4E-42 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 PRINTS PR01005 Flagellar hook-associated protein signature 263 285 1.4E-42 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 SUPERFAMILY SSF64518 137 555 6.02E-36 T 29-03-2018 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 Gene3D G3DSA:1.20.1170.10 3 321 9.3E-6 T 29-03-2018 CVS48_RS16905 d59a3e33a000198e3c8cf444c03706e1 557 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 501 555 3.7E-6 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CVS48_RS28435 7c14dd5558464a892e350773adc2cdd4 402 PIRSF PIRSF000484 5 387 4.3E-68 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CVS48_RS28435 7c14dd5558464a892e350773adc2cdd4 402 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 10 401 46.784 T 29-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CVS48_RS28435 7c14dd5558464a892e350773adc2cdd4 402 SUPERFAMILY SSF54675 7 147 3.77E-44 T 29-03-2018 CVS48_RS28435 7c14dd5558464a892e350773adc2cdd4 402 Gene3D G3DSA:3.20.140.10 11 399 1.6E-99 T 29-03-2018 CVS48_RS28435 7c14dd5558464a892e350773adc2cdd4 402 SUPERFAMILY SSF51690 128 398 2.55E-88 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CVS48_RS28435 7c14dd5558464a892e350773adc2cdd4 402 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 174 399 3.7E-71 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CVS48_RS28435 7c14dd5558464a892e350773adc2cdd4 402 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 13 400 3.4E-147 T 29-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 Gene3D G3DSA:3.40.190.10 183 267 1.1E-20 T 29-03-2018 CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 SUPERFAMILY SSF46785 9 89 2.29E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 Pfam PF03466 LysR substrate binding domain 96 297 2.8E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 9.4E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 SUPERFAMILY SSF53850 98 299 9.31E-40 T 29-03-2018 CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 Gene3D G3DSA:1.10.10.10 8 90 1.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05295 bedca4a8c3d523aa864640d6ffd46145 308 Gene3D G3DSA:3.40.190.10 96 182 2.5E-20 T 29-03-2018 CVS48_RS09235 a26188d45bec618174498a29ddbcbcf7 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 8 224 8.1E-57 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CVS48_RS09235 a26188d45bec618174498a29ddbcbcf7 239 PIRSF PIRSF006293 4 238 2.6E-64 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CVS48_RS09235 a26188d45bec618174498a29ddbcbcf7 239 SUPERFAMILY SSF52402 7 233 2.21E-52 T 29-03-2018 CVS48_RS09235 a26188d45bec618174498a29ddbcbcf7 239 Gene3D G3DSA:3.40.50.620 5 238 1.7E-46 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS09235 a26188d45bec618174498a29ddbcbcf7 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 6 237 49.868 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CVS48_RS09235 a26188d45bec618174498a29ddbcbcf7 239 Pfam PF06508 Queuosine biosynthesis protein QueC 7 231 8.1E-69 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CVS48_RS18030 24cb4816e7e3eb4010fe35bffb9d9eb3 742 Gene3D G3DSA:3.40.718.10 436 705 1.2E-40 T 29-03-2018 CVS48_RS18030 24cb4816e7e3eb4010fe35bffb9d9eb3 742 Gene3D G3DSA:3.40.718.10 57 410 4.5E-44 T 29-03-2018 CVS48_RS18030 24cb4816e7e3eb4010fe35bffb9d9eb3 742 SUPERFAMILY SSF53659 4 741 0.0 T 29-03-2018 CVS48_RS18030 24cb4816e7e3eb4010fe35bffb9d9eb3 742 PIRSF PIRSF009407 1 742 0.0 T 29-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CVS48_RS18030 24cb4816e7e3eb4010fe35bffb9d9eb3 742 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 4 741 0.0 T 29-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CVS48_RS18030 24cb4816e7e3eb4010fe35bffb9d9eb3 742 Pfam PF03971 Monomeric isocitrate dehydrogenase 6 738 0.0 T 29-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CVS48_RS05410 f884f17633155d1bf69b25c43ddf1928 337 SUPERFAMILY SSF53822 66 319 1.32E-63 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS05410 f884f17633155d1bf69b25c43ddf1928 337 Pfam PF13377 Periplasmic binding protein-like domain 174 331 5.4E-33 T 29-03-2018 CVS48_RS05410 f884f17633155d1bf69b25c43ddf1928 337 Gene3D G3DSA:1.10.10.60 1 23 0.0048 T 29-03-2018 CVS48_RS05410 f884f17633155d1bf69b25c43ddf1928 337 Gene3D G3DSA:1.10.260.40 24 61 1.0E-18 T 29-03-2018 CVS48_RS05410 f884f17633155d1bf69b25c43ddf1928 337 Gene3D G3DSA:3.40.50.2300 62 180 5.6E-36 T 29-03-2018 CVS48_RS05410 f884f17633155d1bf69b25c43ddf1928 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 55 2.1E-10 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS05410 f884f17633155d1bf69b25c43ddf1928 337 Gene3D G3DSA:3.40.50.2300 181 317 2.5E-35 T 29-03-2018 CVS48_RS05410 f884f17633155d1bf69b25c43ddf1928 337 SMART SM00354 8 78 1.4E-21 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS05410 f884f17633155d1bf69b25c43ddf1928 337 SUPERFAMILY SSF47413 8 66 7.31E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS18300 44d45f1c37dd37f11321d95eb3f2a22a 239 SUPERFAMILY SSF51206 13 133 1.96E-10 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CVS48_RS18300 44d45f1c37dd37f11321d95eb3f2a22a 239 Gene3D G3DSA:2.60.120.10 11 156 1.0E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS18300 44d45f1c37dd37f11321d95eb3f2a22a 239 SUPERFAMILY SSF46785 153 227 2.95E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18300 44d45f1c37dd37f11321d95eb3f2a22a 239 Gene3D G3DSA:1.10.10.10 157 238 5.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18300 44d45f1c37dd37f11321d95eb3f2a22a 239 Pfam PF13545 Crp-like helix-turn-helix domain 155 220 7.8E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 4 398 2.0E-115 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 Pfam PF03486 HI0933-like protein 2 398 3.8E-135 T 29-03-2018 CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 SUPERFAMILY SSF160996 187 345 2.49E-37 T 29-03-2018 CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 SUPERFAMILY SSF51905 343 400 2.45E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 SUPERFAMILY SSF51905 1 186 2.45E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 Gene3D G3DSA:2.40.30.10 201 271 2.2E-23 T 29-03-2018 CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 Gene3D G3DSA:3.50.50.60 1 200 9.6E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 Gene3D G3DSA:1.10.8.260 272 328 3.1E-18 T 29-03-2018 IPR023166 HI0933 insert-like domain CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 162 2.7E-6 T 29-03-2018 CVS48_RS10565 39f9b31cf1912ec8accfe663c6cfb728 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.7E-6 T 29-03-2018 CVS48_RS07565 247c31f7256e574ed423ac6e753a8b5f 235 Pfam PF00027 Cyclic nucleotide-binding domain 32 118 2.2E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS07565 247c31f7256e574ed423ac6e753a8b5f 235 Gene3D G3DSA:2.60.120.10 6 144 2.8E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS07565 247c31f7256e574ed423ac6e753a8b5f 235 Gene3D G3DSA:1.10.10.10 145 223 6.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07565 247c31f7256e574ed423ac6e753a8b5f 235 Pfam PF13545 Crp-like helix-turn-helix domain 151 222 3.0E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS07565 247c31f7256e574ed423ac6e753a8b5f 235 SMART SM00100 13 134 0.0034 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS07565 247c31f7256e574ed423ac6e753a8b5f 235 SUPERFAMILY SSF46785 149 224 2.34E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07565 247c31f7256e574ed423ac6e753a8b5f 235 SUPERFAMILY SSF51206 12 140 8.38E-22 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CVS48_RS09400 76a5fe3e9fcb6246f808933c979abcce 342 Gene3D G3DSA:3.40.190.10 143 251 1.1E-12 T 29-03-2018 CVS48_RS09400 76a5fe3e9fcb6246f808933c979abcce 342 PIRSF PIRSF017082 9 342 1.5E-72 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09400 76a5fe3e9fcb6246f808933c979abcce 342 SUPERFAMILY SSF53850 137 305 2.96E-13 T 29-03-2018 CVS48_RS09400 76a5fe3e9fcb6246f808933c979abcce 342 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 65 339 5.7E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23525 b14c231ec02ec522177eac0494f12e83 309 Gene3D G3DSA:3.40.190.10 92 181 3.1E-12 T 29-03-2018 CVS48_RS23525 b14c231ec02ec522177eac0494f12e83 309 Gene3D G3DSA:3.40.190.10 182 269 1.1E-24 T 29-03-2018 CVS48_RS23525 b14c231ec02ec522177eac0494f12e83 309 Pfam PF03466 LysR substrate binding domain 93 300 1.4E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS23525 b14c231ec02ec522177eac0494f12e83 309 SUPERFAMILY SSF53850 94 304 4.16E-35 T 29-03-2018 CVS48_RS23525 b14c231ec02ec522177eac0494f12e83 309 SUPERFAMILY SSF46785 6 107 1.03E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23525 b14c231ec02ec522177eac0494f12e83 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.9E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23525 b14c231ec02ec522177eac0494f12e83 309 Gene3D G3DSA:1.10.10.10 1 91 3.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27760 c0caf539e4113aadedb9f352f7681d7a 274 Gene3D G3DSA:3.40.190.80 163 274 1.7E-19 T 29-03-2018 CVS48_RS27760 c0caf539e4113aadedb9f352f7681d7a 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 52 72 1.0E-16 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS27760 c0caf539e4113aadedb9f352f7681d7a 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 1.0E-16 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS27760 c0caf539e4113aadedb9f352f7681d7a 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 74 90 1.0E-16 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS27760 c0caf539e4113aadedb9f352f7681d7a 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 217 241 1.0E-16 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS27760 c0caf539e4113aadedb9f352f7681d7a 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 186 207 1.0E-16 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS27760 c0caf539e4113aadedb9f352f7681d7a 274 Gene3D G3DSA:3.30.540.10 2 162 6.5E-38 T 29-03-2018 CVS48_RS27760 c0caf539e4113aadedb9f352f7681d7a 274 Pfam PF00459 Inositol monophosphatase family 9 272 4.2E-43 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS27760 c0caf539e4113aadedb9f352f7681d7a 274 SUPERFAMILY SSF56655 4 273 1.57E-63 T 29-03-2018 CVS48_RS15505 6f261a8ddae9f942ca238e3cad1a0a68 415 Gene3D G3DSA:3.50.50.60 1 415 4.6E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS15505 6f261a8ddae9f942ca238e3cad1a0a68 415 Pfam PF01266 FAD dependent oxidoreductase 2 399 6.4E-60 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS15505 6f261a8ddae9f942ca238e3cad1a0a68 415 SUPERFAMILY SSF54373 271 361 8.11E-10 T 29-03-2018 CVS48_RS15505 6f261a8ddae9f942ca238e3cad1a0a68 415 SUPERFAMILY SSF51905 107 271 6.6E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS15505 6f261a8ddae9f942ca238e3cad1a0a68 415 SUPERFAMILY SSF51905 1 54 6.6E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS15505 6f261a8ddae9f942ca238e3cad1a0a68 415 SUPERFAMILY SSF51905 361 415 6.6E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS03505 4397ac47310c75fa736e0162e066b54e 320 PRINTS PR00502 NUDIX hydrolase family signature 35 49 9.3E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CVS48_RS03505 4397ac47310c75fa736e0162e066b54e 320 PRINTS PR00502 NUDIX hydrolase family signature 49 64 9.3E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CVS48_RS03505 4397ac47310c75fa736e0162e066b54e 320 Gene3D G3DSA:3.20.20.70 132 320 7.2E-21 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS03505 4397ac47310c75fa736e0162e066b54e 320 Pfam PF00293 NUDIX domain 9 114 3.8E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CVS48_RS03505 4397ac47310c75fa736e0162e066b54e 320 SUPERFAMILY SSF51391 118 319 2.09E-40 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS03505 4397ac47310c75fa736e0162e066b54e 320 SUPERFAMILY SSF55811 7 116 4.47E-35 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS03505 4397ac47310c75fa736e0162e066b54e 320 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CVS48_RS03505 4397ac47310c75fa736e0162e066b54e 320 Pfam PF02581 Thiamine monophosphate synthase 148 318 1.2E-36 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS03505 4397ac47310c75fa736e0162e066b54e 320 Gene3D G3DSA:3.90.79.10 4 131 2.9E-30 T 29-03-2018 CVS48_RS06950 81ecdb72eac311eecec21deb302cae4c 288 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 278 1.7E-14 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS06950 81ecdb72eac311eecec21deb302cae4c 288 Gene3D G3DSA:3.60.10.10 2 286 3.7E-32 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS06950 81ecdb72eac311eecec21deb302cae4c 288 SUPERFAMILY SSF56219 4 194 1.18E-41 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS06950 81ecdb72eac311eecec21deb302cae4c 288 SUPERFAMILY SSF56219 238 285 1.18E-41 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS03235 817125150074bc0c63d34b610793d8fb 362 SUPERFAMILY SSF50331 243 326 9.64E-7 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS03235 817125150074bc0c63d34b610793d8fb 362 SUPERFAMILY SSF52540 4 247 4.52E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03235 817125150074bc0c63d34b610793d8fb 362 SMART SM00382 28 217 5.1E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03235 817125150074bc0c63d34b610793d8fb 362 Gene3D G3DSA:3.40.50.300 2 257 6.4E-71 T 29-03-2018 CVS48_RS03235 817125150074bc0c63d34b610793d8fb 362 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS03235 817125150074bc0c63d34b610793d8fb 362 Pfam PF00005 ABC transporter 19 167 8.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS16300 630b4d64e1f6d4cb33bac7066d149c0d 223 Gene3D G3DSA:3.40.50.2300 1 115 1.2E-30 T 29-03-2018 CVS48_RS16300 630b4d64e1f6d4cb33bac7066d149c0d 223 SMART SM00862 145 216 2.4E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS16300 630b4d64e1f6d4cb33bac7066d149c0d 223 SMART SM00448 1 112 3.2E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS16300 630b4d64e1f6d4cb33bac7066d149c0d 223 Gene3D G3DSA:1.10.10.10 116 223 2.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16300 630b4d64e1f6d4cb33bac7066d149c0d 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 1.5E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS16300 630b4d64e1f6d4cb33bac7066d149c0d 223 SUPERFAMILY SSF52172 1 176 8.25E-36 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS16300 630b4d64e1f6d4cb33bac7066d149c0d 223 Pfam PF00072 Response regulator receiver domain 3 112 2.1E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS08820 b543ac47284e759c670ac02a73e3cdb6 468 Pfam PF00324 Amino acid permease 17 448 1.2E-103 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CVS48_RS08820 b543ac47284e759c670ac02a73e3cdb6 468 PIRSF PIRSF006060 1 466 5.8E-74 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CVS48_RS25370 93d25c794e011d2e3defb9a869a3a82f 217 Gene3D G3DSA:3.40.50.1860 2 111 2.8E-4 T 29-03-2018 CVS48_RS25370 93d25c794e011d2e3defb9a869a3a82f 217 Pfam PF01177 Asp/Glu/Hydantoin racemase 67 208 7.0E-7 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS25370 93d25c794e011d2e3defb9a869a3a82f 217 Gene3D G3DSA:3.40.50.1860 112 203 2.3E-10 T 29-03-2018 CVS48_RS05665 d6e5cf6b67de77bf918985f337858b35 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 316 1.6E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS05665 d6e5cf6b67de77bf918985f337858b35 321 SUPERFAMILY SSF53850 85 284 3.75E-10 T 29-03-2018 CVS48_RS05665 d6e5cf6b67de77bf918985f337858b35 321 PIRSF PIRSF017082 1 320 3.8E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS05665 d6e5cf6b67de77bf918985f337858b35 321 Gene3D G3DSA:3.40.190.10 120 230 2.6E-7 T 29-03-2018 CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 142 310 2.1E-46 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 Gene3D G3DSA:3.30.450.20 11 136 8.4E-21 T 29-03-2018 CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 Gene3D G3DSA:3.30.70.270 137 312 4.9E-47 T 29-03-2018 CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 SMART SM00267 135 311 9.9E-54 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 SUPERFAMILY SSF55073 151 309 5.81E-42 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 SMART SM00086 86 128 3.1E-7 T 29-03-2018 IPR001610 PAC motif CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 Pfam PF08447 PAS fold 36 122 3.0E-15 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 Pfam PF00990 Diguanylate cyclase, GGDEF domain 148 307 3.9E-47 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 135 5.7E-12 T 29-03-2018 IPR000014 PAS domain CVS48_RS11295 d9bffdaf900083a6d46b695c76970591 315 SUPERFAMILY SSF55785 17 130 2.27E-20 T 29-03-2018 IPR000014 PAS domain CVS48_RS27210 7c946fa040e495484002864f77f5d872 219 SMART SM00448 1 112 1.7E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS27210 7c946fa040e495484002864f77f5d872 219 SUPERFAMILY SSF52172 1 177 2.64E-36 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS27210 7c946fa040e495484002864f77f5d872 219 Pfam PF00072 Response regulator receiver domain 3 112 1.5E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS27210 7c946fa040e495484002864f77f5d872 219 Gene3D G3DSA:3.40.50.2300 1 119 2.3E-33 T 29-03-2018 CVS48_RS27210 7c946fa040e495484002864f77f5d872 219 SMART SM00862 145 216 2.4E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS27210 7c946fa040e495484002864f77f5d872 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 6.5E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS27210 7c946fa040e495484002864f77f5d872 219 Gene3D G3DSA:1.10.10.10 120 219 9.2E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 SUPERFAMILY SSF53098 1 154 1.21E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 153 1.0E-44 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 Gene3D G3DSA:3.30.420.10 1 156 1.5E-45 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 6.0E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 6.0E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 6.0E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 6.0E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 6.0E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 153 47.324 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CVS48_RS01420 fe9f5514172da593993e537fdb4bb331 182 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 150 1.7E-49 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 Gene3D G3DSA:1.25.40.20 27 141 7.6E-25 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 SUPERFAMILY SSF48403 44 219 2.04E-40 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 SMART SM00248 164 193 1.0E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 SMART SM00248 101 130 0.49 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 SMART SM00248 131 160 2.5E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 SMART SM00248 67 97 1200.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 Pfam PF12796 Ankyrin repeats (3 copies) 45 130 6.6E-7 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 Pfam PF12796 Ankyrin repeats (3 copies) 132 195 3.1E-14 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 PRINTS PR01415 Ankyrin repeat signature 180 194 2.8E-8 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 PRINTS PR01415 Ankyrin repeat signature 132 147 2.8E-8 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS17310 a320caf767ab54a5207a969d2659f036 291 Gene3D G3DSA:1.25.40.20 142 246 1.1E-25 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS10795 fd8d73e1d6cea5f80cc92b57c2e31e22 439 Pfam PF09298 Fumarylacetoacetase N-terminal 30 131 2.0E-23 T 29-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CVS48_RS10795 fd8d73e1d6cea5f80cc92b57c2e31e22 439 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 137 429 5.5E-51 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS10795 fd8d73e1d6cea5f80cc92b57c2e31e22 439 Gene3D G3DSA:3.90.850.10 129 422 8.2E-81 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS10795 fd8d73e1d6cea5f80cc92b57c2e31e22 439 Gene3D G3DSA:2.30.30.230 15 127 1.2E-29 T 29-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CVS48_RS10795 fd8d73e1d6cea5f80cc92b57c2e31e22 439 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 15 437 4.2E-158 T 29-03-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CVS48_RS10795 fd8d73e1d6cea5f80cc92b57c2e31e22 439 SUPERFAMILY SSF56529 133 437 1.57E-88 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS10795 fd8d73e1d6cea5f80cc92b57c2e31e22 439 SUPERFAMILY SSF63433 14 131 2.09E-31 T 29-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CVS48_RS16715 d7ca8f507dfa1465570d1bc8df25d15b 166 SUPERFAMILY SSF51161 20 163 1.52E-31 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS16715 d7ca8f507dfa1465570d1bc8df25d15b 166 Gene3D G3DSA:2.160.10.10 1 158 7.8E-33 T 29-03-2018 CVS48_RS16715 d7ca8f507dfa1465570d1bc8df25d15b 166 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 107 142 4.8E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS03665 60cc076cdd5f9e49470a5ae65f500272 280 Gene3D G3DSA:3.40.190.10 155 227 4.1E-5 T 29-03-2018 CVS48_RS03665 60cc076cdd5f9e49470a5ae65f500272 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 47 266 1.4E-22 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS03665 60cc076cdd5f9e49470a5ae65f500272 280 SUPERFAMILY SSF53850 47 267 2.35E-27 T 29-03-2018 CVS48_RS03665 60cc076cdd5f9e49470a5ae65f500272 280 SMART SM00062 46 279 0.0032 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS03665 60cc076cdd5f9e49470a5ae65f500272 280 Gene3D G3DSA:3.40.190.10 32 154 3.2E-15 T 29-03-2018 CVS48_RS25045 e92e07883cbb8f6f767b4cae1ab742fb 294 SUPERFAMILY SSF55781 109 290 2.16E-41 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS25045 e92e07883cbb8f6f767b4cae1ab742fb 294 Pfam PF09339 IclR helix-turn-helix domain 45 94 8.2E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS25045 e92e07883cbb8f6f767b4cae1ab742fb 294 Gene3D G3DSA:1.10.10.10 37 114 8.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25045 e92e07883cbb8f6f767b4cae1ab742fb 294 SUPERFAMILY SSF46785 43 116 2.26E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25045 e92e07883cbb8f6f767b4cae1ab742fb 294 Pfam PF01614 Bacterial transcriptional regulator 165 286 1.7E-22 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS25045 e92e07883cbb8f6f767b4cae1ab742fb 294 Gene3D G3DSA:3.30.450.40 115 294 6.2E-45 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS25045 e92e07883cbb8f6f767b4cae1ab742fb 294 SMART SM00346 43 133 5.5E-24 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS18665 f85d1e5b43c3ebb63f4573457dbced8b 266 Gene3D G3DSA:3.90.850.10 1 266 3.4E-46 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS18665 f85d1e5b43c3ebb63f4573457dbced8b 266 SUPERFAMILY SSF56529 1 266 8.24E-78 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS18665 f85d1e5b43c3ebb63f4573457dbced8b 266 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 84 264 2.8E-7 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS18665 f85d1e5b43c3ebb63f4573457dbced8b 266 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 2 266 8.0E-138 T 29-03-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 CVS48_RS26260 c4b3a0dfdd3cb1cd4a6190c3190fa7ad 249 SUPERFAMILY SSF56112 50 202 1.13E-19 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS26260 c4b3a0dfdd3cb1cd4a6190c3190fa7ad 249 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 16 245 27.298 T 29-03-2018 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 CVS48_RS26260 c4b3a0dfdd3cb1cd4a6190c3190fa7ad 249 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 50 225 3.4E-46 T 29-03-2018 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 CVS48_RS26260 c4b3a0dfdd3cb1cd4a6190c3190fa7ad 249 Gene3D G3DSA:1.10.510.10 96 243 1.2E-15 T 29-03-2018 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 SUPERFAMILY SSF51998 371 815 2.53E-178 T 29-03-2018 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 SUPERFAMILY SSF51998 846 914 2.53E-178 T 29-03-2018 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 SUPERFAMILY SSF48168 160 370 9.94E-59 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 295 366 4.2E-21 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 Gene3D G3DSA:3.20.70.20 278 918 3.0E-211 T 29-03-2018 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 Pfam PF03477 ATP cone domain 34 130 2.0E-17 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 298 914 5.4E-208 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 755 777 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 447 466 9.7E-43 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 690 713 9.7E-43 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 662 684 9.7E-43 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 582 593 9.7E-43 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 624 647 9.7E-43 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 766 793 9.7E-43 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS03115 acc2ba7b6d37bbfa6a58fc79c05625dc 976 Pfam PF02867 Ribonucleotide reductase, barrel domain 372 911 7.9E-181 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 373 32.97 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 SUPERFAMILY SSF55347 135 360 1.61E-70 T 29-03-2018 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 SUPERFAMILY SSF51735 4 148 3.94E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 122 5.7E-22 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 267 281 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 Gene3D G3DSA:3.30.360.10 146 356 9.8E-56 T 29-03-2018 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 359 1.9E-55 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 Gene3D G3DSA:3.40.50.720 2 145 1.4E-16 T 29-03-2018 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 4 371 4.0E-178 T 29-03-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 PIRSF PIRSF000148 3 376 3.0E-61 T 29-03-2018 CVS48_RS14975 0e9b75c00dac7406120394cf1147460c 376 SMART SM00859 4 123 1.3E-26 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CVS48_RS16890 c9bb51250c62f613e21b4da8e56be7a1 229 Hamap MF_00415 Flagellar L-ring protein [flgH]. 3 227 26.69 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CVS48_RS16890 c9bb51250c62f613e21b4da8e56be7a1 229 Pfam PF02107 Flagellar L-ring protein 47 226 6.4E-57 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CVS48_RS16890 c9bb51250c62f613e21b4da8e56be7a1 229 PRINTS PR01008 Flagellar L-ring protein signature 190 204 6.1E-27 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CVS48_RS16890 c9bb51250c62f613e21b4da8e56be7a1 229 PRINTS PR01008 Flagellar L-ring protein signature 71 83 6.1E-27 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CVS48_RS16890 c9bb51250c62f613e21b4da8e56be7a1 229 PRINTS PR01008 Flagellar L-ring protein signature 206 220 6.1E-27 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CVS48_RS16890 c9bb51250c62f613e21b4da8e56be7a1 229 PRINTS PR01008 Flagellar L-ring protein signature 143 158 6.1E-27 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CVS48_RS16890 c9bb51250c62f613e21b4da8e56be7a1 229 PRINTS PR01008 Flagellar L-ring protein signature 169 185 6.1E-27 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CVS48_RS13460 05aae5be338d14e9e7efe0aa58f991de 288 SMART SM00346 14 104 8.0E-20 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS13460 05aae5be338d14e9e7efe0aa58f991de 288 SUPERFAMILY SSF46785 15 87 7.89E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13460 05aae5be338d14e9e7efe0aa58f991de 288 SUPERFAMILY SSF55781 80 257 2.29E-46 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13460 05aae5be338d14e9e7efe0aa58f991de 288 Pfam PF09339 IclR helix-turn-helix domain 16 67 1.7E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS13460 05aae5be338d14e9e7efe0aa58f991de 288 Pfam PF01614 Bacterial transcriptional regulator 132 257 3.3E-28 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS13460 05aae5be338d14e9e7efe0aa58f991de 288 Gene3D G3DSA:3.30.450.40 80 263 1.3E-45 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13460 05aae5be338d14e9e7efe0aa58f991de 288 Gene3D G3DSA:1.10.10.10 14 75 1.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 238 250 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 65 261 9.1E-90 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 82 102 1.7E-62 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 211 232 1.7E-62 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 235 260 1.7E-62 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 190 210 1.7E-62 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 63 82 1.7E-62 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 102 121 1.7E-62 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 190 205 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 133 147 2.9E-31 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 251 261 2.9E-31 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 61 70 2.9E-31 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 121 133 2.9E-31 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 161 173 2.9E-31 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 183 195 2.9E-31 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CVS48_RS16950 d84c98fa6625935d32e02865728cbc18 263 Pfam PF00813 FliP family 65 257 1.7E-77 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CVS48_RS11480 c788d52c0698894a04ea0cbb643799bd 256 Gene3D G3DSA:3.40.225.10 16 255 8.0E-46 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS11480 c788d52c0698894a04ea0cbb643799bd 256 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 31 207 1.5E-34 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS11480 c788d52c0698894a04ea0cbb643799bd 256 SUPERFAMILY SSF53639 26 232 6.08E-54 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS11480 c788d52c0698894a04ea0cbb643799bd 256 SMART SM01007 30 207 2.6E-39 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 SUPERFAMILY SSF46785 3 79 1.51E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.2E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 Gene3D G3DSA:3.40.190.10 88 172 5.2E-12 T 29-03-2018 CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 Gene3D G3DSA:3.40.190.10 173 257 3.3E-12 T 29-03-2018 CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 Pfam PF03466 LysR substrate binding domain 87 291 1.2E-28 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 Gene3D G3DSA:1.10.10.10 2 81 4.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16235 697a2774792f47bffcebe7fbcff861e2 300 SUPERFAMILY SSF53850 87 293 1.3E-26 T 29-03-2018 CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 SMART SM00322 60 125 2.9E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 SUPERFAMILY SSF54821 108 206 1.12E-39 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 5.2E-40 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 SUPERFAMILY SSF54814 2 106 1.33E-36 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 Gene3D G3DSA:3.30.1140.32 108 207 1.0E-37 T 29-03-2018 CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 6.0E-92 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 Pfam PF07650 KH domain 39 110 3.1E-20 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 Gene3D G3DSA:3.30.300.20 17 107 1.9E-27 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS06415 27d1abe7cbed8d11ca336ac0c6036e76 264 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.498 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 SUPERFAMILY SSF51621 464 787 9.95E-91 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 Gene3D G3DSA:3.20.20.60 478 788 5.8E-100 T 29-03-2018 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 SUPERFAMILY SSF56059 1 383 1.29E-106 T 29-03-2018 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 347 5.0E-115 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 PIRSF PIRSF000854 1 788 0.0 T 29-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 692 710 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 Gene3D G3DSA:3.50.30.10 356 477 2.3E-37 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 Pfam PF00391 PEP-utilising enzyme, mobile domain 382 453 1.3E-26 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 Gene3D G3DSA:3.30.1490.20 1 190 2.1E-56 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 Gene3D G3DSA:3.30.470.20 191 355 2.8E-45 T 29-03-2018 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 SUPERFAMILY SSF52009 345 465 8.11E-35 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 787 0.0 T 29-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 CVS48_RS17215 19a2f02992f7c625a5c1c058b8b68f29 788 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 478 787 3.7E-55 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CVS48_RS17070 1caac2656346f992f2e39c5318f055fe 436 Pfam PF08245 Mur ligase middle domain 53 267 5.7E-10 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS17070 1caac2656346f992f2e39c5318f055fe 436 Gene3D G3DSA:3.40.1190.10 7 292 9.2E-75 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS17070 1caac2656346f992f2e39c5318f055fe 436 SUPERFAMILY SSF53623 11 289 1.96E-85 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS17070 1caac2656346f992f2e39c5318f055fe 436 Gene3D G3DSA:3.90.190.20 293 436 7.7E-29 T 29-03-2018 CVS48_RS17070 1caac2656346f992f2e39c5318f055fe 436 PIRSF PIRSF001563 8 436 1.2E-102 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CVS48_RS17070 1caac2656346f992f2e39c5318f055fe 436 SUPERFAMILY SSF53244 291 432 1.23E-30 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS17070 1caac2656346f992f2e39c5318f055fe 436 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 431 6.7E-98 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CVS48_RS23670 b2be50a2c60fb44fa4ce61ba9ff62fae 744 Gene3D G3DSA:3.40.190.10 292 423 1.9E-13 T 29-03-2018 CVS48_RS23670 b2be50a2c60fb44fa4ce61ba9ff62fae 744 Gene3D G3DSA:3.10.105.10 424 659 2.7E-42 T 29-03-2018 CVS48_RS23670 b2be50a2c60fb44fa4ce61ba9ff62fae 744 SUPERFAMILY SSF53850 38 135 2.71E-82 T 29-03-2018 CVS48_RS23670 b2be50a2c60fb44fa4ce61ba9ff62fae 744 SUPERFAMILY SSF53850 171 677 2.71E-82 T 29-03-2018 CVS48_RS23670 b2be50a2c60fb44fa4ce61ba9ff62fae 744 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 170 603 6.3E-47 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS23670 b2be50a2c60fb44fa4ce61ba9ff62fae 744 Gene3D G3DSA:3.90.76.10 49 291 5.1E-29 T 29-03-2018 CVS48_RS01540 d08f0d9b0218ccd242406c9504db0c5e 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 303 3.3E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS01540 d08f0d9b0218ccd242406c9504db0c5e 304 SUPERFAMILY SSF161098 87 292 8.9E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS01540 d08f0d9b0218ccd242406c9504db0c5e 304 Gene3D G3DSA:1.10.3720.10 10 293 7.8E-38 T 29-03-2018 CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 Gene3D G3DSA:1.10.10.60 300 347 3.9E-13 T 29-03-2018 CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 SMART SM00342 258 341 3.5E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 SUPERFAMILY SSF52317 29 220 2.9E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 295 337 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 SUPERFAMILY SSF46689 294 343 2.64E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 Gene3D G3DSA:3.40.50.880 24 238 3.2E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 Pfam PF01965 DJ-1/PfpI family 67 202 9.1E-14 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 Pfam PF12833 Helix-turn-helix domain 264 343 1.1E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 Gene3D G3DSA:1.10.10.60 239 299 8.2E-13 T 29-03-2018 CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 SUPERFAMILY SSF46689 242 292 5.73E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 310 325 1.3E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS14215 a3dc8cfb01f888e137d06a739daab123 359 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 325 341 1.3E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS07670 dd36616c7a26c5a7fc375f1b1757332d 248 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 29 211 4.4E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS07670 dd36616c7a26c5a7fc375f1b1757332d 248 Pfam PF13419 Haloacid dehalogenase-like hydrolase 30 211 2.3E-9 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS07670 dd36616c7a26c5a7fc375f1b1757332d 248 SUPERFAMILY SSF56784 27 239 3.84E-32 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS07670 dd36616c7a26c5a7fc375f1b1757332d 248 Gene3D G3DSA:3.40.50.1000 48 218 2.4E-22 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS07670 dd36616c7a26c5a7fc375f1b1757332d 248 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 28 210 7.3E-47 T 29-03-2018 IPR010237 Pyrimidine 5-nucleotidase CVS48_RS01350 af914af59a9d2f59b1949442552a2b95 366 Pfam PF00561 alpha/beta hydrolase fold 103 198 7.2E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS01350 af914af59a9d2f59b1949442552a2b95 366 PIRSF PIRSF005211 2 366 1.6E-118 T 29-03-2018 IPR012020 AB hydrolase 4 family CVS48_RS01350 af914af59a9d2f59b1949442552a2b95 366 Gene3D G3DSA:3.40.50.1820 67 237 2.0E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS01350 af914af59a9d2f59b1949442552a2b95 366 Gene3D G3DSA:3.40.50.1820 238 354 1.3E-6 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS01350 af914af59a9d2f59b1949442552a2b95 366 SUPERFAMILY SSF53474 264 343 1.9E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS01350 af914af59a9d2f59b1949442552a2b95 366 SUPERFAMILY SSF53474 85 231 1.9E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 Gene3D G3DSA:2.40.160.10 7 370 2.7E-68 T 29-03-2018 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 54 65 1.5E-6 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 157 168 1.5E-6 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 195 207 1.5E-6 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 1.5E-6 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 327 344 1.5E-6 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 Pfam PF13609 Gram-negative porin 7 350 5.3E-60 T 29-03-2018 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 PRINTS PR00184 Neisseria sp. porin signature 324 348 3.8E-10 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 PRINTS PR00184 Neisseria sp. porin signature 56 81 3.8E-10 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 PRINTS PR00184 Neisseria sp. porin signature 156 173 3.8E-10 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS07830 c8ab2c7ecc28c35649cda72bceb2ad93 370 SUPERFAMILY SSF56935 22 370 7.94E-72 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Gene3D G3DSA:2.40.50.140 111 191 1.4E-10 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Gene3D G3DSA:2.40.50.140 196 280 4.2E-27 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Gene3D G3DSA:2.40.50.140 459 540 5.7E-18 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PRINTS PR00681 Ribosomal protein S1 signature 304 323 5.2E-81 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PRINTS PR00681 Ribosomal protein S1 signature 122 138 5.2E-81 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PRINTS PR00681 Ribosomal protein S1 signature 98 117 5.2E-81 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PRINTS PR00681 Ribosomal protein S1 signature 140 157 5.2E-81 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PRINTS PR00681 Ribosomal protein S1 signature 169 189 5.2E-81 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PRINTS PR00681 Ribosomal protein S1 signature 53 67 5.2E-81 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PRINTS PR00681 Ribosomal protein S1 signature 35 53 5.2E-81 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PRINTS PR00681 Ribosomal protein S1 signature 226 247 5.2E-81 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PRINTS PR00681 Ribosomal protein S1 signature 344 362 5.2E-81 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SUPERFAMILY SSF50249 443 544 2.46E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SMART SM00316 204 274 1.9E-29 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SMART SM00316 117 185 2.6E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SMART SM00316 289 361 4.2E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SMART SM00316 33 101 0.0041 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SMART SM00316 376 448 2.0E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SMART SM00316 463 534 1.3E-15 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SUPERFAMILY SSF50249 18 127 8.58E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Gene3D G3DSA:2.40.50.140 288 362 6.9E-25 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SUPERFAMILY SSF50249 117 199 7.25E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 17 534 4.9E-206 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SUPERFAMILY SSF50249 360 451 3.73E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Gene3D G3DSA:2.40.50.140 11 104 2.3E-7 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Gene3D G3DSA:2.40.50.140 373 454 2.4E-21 T 29-03-2018 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 PIRSF PIRSF002111 3 548 3.9E-213 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SUPERFAMILY SSF50249 204 291 1.29E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 SUPERFAMILY SSF50249 269 385 5.15E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Pfam PF00575 S1 RNA binding domain 33 99 4.9E-6 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Pfam PF00575 S1 RNA binding domain 463 534 4.6E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Pfam PF00575 S1 RNA binding domain 376 448 4.6E-18 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Pfam PF00575 S1 RNA binding domain 290 361 1.3E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Pfam PF00575 S1 RNA binding domain 204 274 1.6E-23 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS27495 de2fcd5f8e88cef7f33d53e65422ad94 575 Pfam PF00575 S1 RNA binding domain 117 185 3.5E-12 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS03875 9b89a819bbfb527f6335225d071088ad 172 ProSitePatterns PS00213 Lipocalin signature. 32 43 - T 29-03-2018 IPR022272 Lipocalin family conserved site CVS48_RS03875 9b89a819bbfb527f6335225d071088ad 172 PIRSF PIRSF036893 1 172 3.0E-61 T 29-03-2018 IPR022271 Lipocalin, ApoD type CVS48_RS03875 9b89a819bbfb527f6335225d071088ad 172 SUPERFAMILY SSF50814 15 171 1.87E-46 T 29-03-2018 IPR012674 Calycin CVS48_RS03875 9b89a819bbfb527f6335225d071088ad 172 Pfam PF08212 Lipocalin-like domain 31 171 1.5E-52 T 29-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain CVS48_RS03875 9b89a819bbfb527f6335225d071088ad 172 PRINTS PR01171 Bacterial lipocalin signature 133 144 7.6E-13 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 CVS48_RS03875 9b89a819bbfb527f6335225d071088ad 172 PRINTS PR01171 Bacterial lipocalin signature 118 126 7.6E-13 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 CVS48_RS03875 9b89a819bbfb527f6335225d071088ad 172 PRINTS PR01171 Bacterial lipocalin signature 101 115 7.6E-13 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 CVS48_RS03875 9b89a819bbfb527f6335225d071088ad 172 PRINTS PR01171 Bacterial lipocalin signature 31 45 7.6E-13 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 CVS48_RS03875 9b89a819bbfb527f6335225d071088ad 172 Gene3D G3DSA:2.40.128.20 1 172 2.4E-43 T 29-03-2018 IPR012674 Calycin CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 Pfam PF03466 LysR substrate binding domain 98 298 4.2E-28 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 Gene3D G3DSA:3.40.190.10 185 270 5.2E-18 T 29-03-2018 CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 SUPERFAMILY SSF53850 90 296 2.02E-44 T 29-03-2018 CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 8.2E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 SUPERFAMILY SSF46785 2 85 1.15E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 Gene3D G3DSA:1.10.10.10 1 86 6.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01675 e38c68d34e91d4a1e16af116db18956b 312 Gene3D G3DSA:3.40.190.10 98 184 7.8E-16 T 29-03-2018 CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 Gene3D G3DSA:3.30.450.20 160 278 7.6E-21 T 29-03-2018 CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 Gene3D G3DSA:3.30.70.270 354 524 4.3E-52 T 29-03-2018 CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 Pfam PF02743 Cache domain 63 263 5.5E-25 T 29-03-2018 IPR033479 Double Cache domain 1 CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 SUPERFAMILY SSF55073 366 518 7.85E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 SUPERFAMILY SSF103190 182 262 3.14E-12 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 358 517 1.1E-44 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 Gene3D G3DSA:3.30.450.20 51 159 1.9E-9 T 29-03-2018 CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 SUPERFAMILY SSF103190 65 172 3.53E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 SMART SM00267 350 517 4.0E-51 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS02250 bebc68e0907be3acb59a3d4d7f9d850f 532 Pfam PF00990 Diguanylate cyclase, GGDEF domain 362 512 3.7E-40 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS09005 e605d4ffa478268403db2f2964c65608 495 PIRSF PIRSF002744 1 478 6.8E-101 T 29-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CVS48_RS09005 e605d4ffa478268403db2f2964c65608 495 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 23 452 2.3E-38 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 Gene3D G3DSA:3.40.50.720 52 264 2.7E-66 T 29-03-2018 CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 Gene3D G3DSA:3.40.50.720 1 51 6.2E-7 T 29-03-2018 CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 SUPERFAMILY SSF51735 6 258 1.48E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 258 7.0E-68 T 29-03-2018 CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.9E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.9E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20185 23d196335f7629fc304fadbaca99964a 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.9E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 Gene3D G3DSA:3.40.50.620 221 398 5.9E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 Gene3D G3DSA:3.40.50.880 1 220 1.1E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 211 530 7.7E-143 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 Gene3D G3DSA:3.30.300.10 399 530 1.9E-51 T 29-03-2018 CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 SUPERFAMILY SSF54810 403 530 5.36E-47 T 29-03-2018 CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 202 2.8E-69 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 Pfam PF00958 GMP synthase C terminal domain 444 529 1.8E-41 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 530 54.486 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 Pfam PF02540 NAD synthase 221 289 1.3E-8 T 29-03-2018 IPR022310 NAD/GMP synthase CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 SUPERFAMILY SSF52402 195 417 1.39E-56 T 29-03-2018 CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 Pfam PF00117 Glutamine amidotransferase class-I 7 196 1.3E-34 T 29-03-2018 IPR017926 Glutamine amidotransferase CVS48_RS20930 440c0e18cd9ad99060f7d2a61d765a44 530 SUPERFAMILY SSF52317 1 235 2.79E-56 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS02840 e22970304940118ad2e249a070166d57 153 Hamap MF_00042 Ribonuclease H [rnhA]. 8 153 33.125 T 29-03-2018 IPR022892 Ribonuclease HI GO:0004523 CVS48_RS02840 e22970304940118ad2e249a070166d57 153 SUPERFAMILY SSF53098 10 148 1.09E-58 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS02840 e22970304940118ad2e249a070166d57 153 Gene3D G3DSA:3.30.420.10 5 150 3.9E-53 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS02840 e22970304940118ad2e249a070166d57 153 Pfam PF00075 RNase H 9 146 2.1E-49 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CVS48_RS13945 4a7e2722027744b4c733a2ef3b1e88b7 321 SUPERFAMILY SSF53850 96 291 3.69E-17 T 29-03-2018 CVS48_RS13945 4a7e2722027744b4c733a2ef3b1e88b7 321 PIRSF PIRSF017082 1 321 1.9E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13945 4a7e2722027744b4c733a2ef3b1e88b7 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 316 2.1E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13945 4a7e2722027744b4c733a2ef3b1e88b7 321 Gene3D G3DSA:3.40.190.10 120 231 1.4E-16 T 29-03-2018 CVS48_RS14645 618791b7f1cb80e0ea575cd34620b9a4 224 Pfam PF07883 Cupin domain 139 208 5.5E-11 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS14645 618791b7f1cb80e0ea575cd34620b9a4 224 Gene3D G3DSA:1.10.260.40 23 92 1.5E-15 T 29-03-2018 CVS48_RS14645 618791b7f1cb80e0ea575cd34620b9a4 224 SMART SM00530 35 90 2.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS14645 618791b7f1cb80e0ea575cd34620b9a4 224 SUPERFAMILY SSF47413 30 94 8.16E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS14645 618791b7f1cb80e0ea575cd34620b9a4 224 SUPERFAMILY SSF51182 99 210 1.29E-19 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS14645 618791b7f1cb80e0ea575cd34620b9a4 224 Gene3D G3DSA:2.60.120.10 93 223 2.3E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS14645 618791b7f1cb80e0ea575cd34620b9a4 224 Pfam PF01381 Helix-turn-helix 36 87 3.6E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 355 362 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 SUPERFAMILY SSF53187 179 500 5.65E-118 T 29-03-2018 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 494 2.2E-120 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 SUPERFAMILY SSF52949 1 184 4.59E-29 T 29-03-2018 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 Gene3D G3DSA:3.40.220.10 1 162 2.3E-20 T 29-03-2018 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 142 3.3E-18 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 Gene3D G3DSA:3.40.630.10 170 502 5.2E-133 T 29-03-2018 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 PRINTS PR00481 Cytosol aminopeptidase signature 270 287 3.5E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 PRINTS PR00481 Cytosol aminopeptidase signature 351 371 3.5E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 PRINTS PR00481 Cytosol aminopeptidase signature 292 313 3.5E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 PRINTS PR00481 Cytosol aminopeptidase signature 379 394 3.5E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 PRINTS PR00481 Cytosol aminopeptidase signature 329 350 3.5E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CVS48_RS28205 0c0c0f2e7789e356e2511d51b55a034e 502 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 502 35.76 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CVS48_RS19230 e31a1111455cbf1121b1bcd72e4f3fbb 302 SUPERFAMILY SSF103481 52 153 1.96E-15 T 29-03-2018 CVS48_RS19230 e31a1111455cbf1121b1bcd72e4f3fbb 302 SUPERFAMILY SSF103481 194 292 9.42E-15 T 29-03-2018 CVS48_RS19230 e31a1111455cbf1121b1bcd72e4f3fbb 302 Pfam PF00892 EamA-like transporter family 163 284 1.6E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS19230 e31a1111455cbf1121b1bcd72e4f3fbb 302 Pfam PF00892 EamA-like transporter family 18 149 1.1E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS04205 61c6d267732469a897aba3b034437671 262 Pfam PF13098 Thioredoxin-like domain 141 261 6.0E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS04205 61c6d267732469a897aba3b034437671 262 SUPERFAMILY SSF52833 122 261 2.14E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS04205 61c6d267732469a897aba3b034437671 262 Pfam PF10411 Disulfide bond isomerase protein N-terminus 60 112 2.5E-10 T 29-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal CVS48_RS04205 61c6d267732469a897aba3b034437671 262 Gene3D G3DSA:3.40.30.10 131 262 5.6E-21 T 29-03-2018 CVS48_RS04205 61c6d267732469a897aba3b034437671 262 Gene3D G3DSA:3.10.450.70 53 113 2.1E-10 T 29-03-2018 CVS48_RS04205 61c6d267732469a897aba3b034437671 262 ProSitePatterns PS00194 Thioredoxin family active site. 148 166 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CVS48_RS12000 de6ec0413ed07c827dd401a8f3755015 145 ProDom PD498860 RC0070 109 140 6.0E-4 T 29-03-2018 CVS48_RS12000 de6ec0413ed07c827dd401a8f3755015 145 Pfam PF07007 Lysozyme inhibitor LprI 36 126 3.6E-21 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 Gene3D G3DSA:3.40.50.1000 528 653 3.6E-36 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 239 354 1.0E-21 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 607 727 1.7E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 91 189 2.3E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 495 513 5.5E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 670 695 5.5E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 638 654 5.5E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 610 626 5.5E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 SUPERFAMILY SSF81660 340 541 3.27E-50 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 SUPERFAMILY SSF56784 331 351 2.96E-56 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 SUPERFAMILY SSF56784 492 742 2.96E-56 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 Gene3D G3DSA:3.40.1110.10 373 527 2.8E-27 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 SUPERFAMILY SSF81665 12 123 8.76E-115 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 SUPERFAMILY SSF81665 688 896 8.76E-115 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 SUPERFAMILY SSF81665 233 327 8.76E-115 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 Pfam PF00690 Cation transporter/ATPase, N-terminus 13 79 6.0E-18 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 Pfam PF00702 haloacid dehalogenase-like hydrolase 330 652 1.3E-20 T 29-03-2018 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 6.4E-40 T 29-03-2018 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 559 569 6.4E-40 T 29-03-2018 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 662 674 6.4E-40 T 29-03-2018 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 333 347 6.4E-40 T 29-03-2018 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 537 548 6.4E-40 T 29-03-2018 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 638 657 6.4E-40 T 29-03-2018 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 Pfam PF00689 Cation transporting ATPase, C-terminus 723 894 6.8E-39 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 SUPERFAMILY SSF81653 123 231 4.71E-29 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 335 341 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 Gene3D G3DSA:1.20.1110.10 654 900 3.8E-57 T 29-03-2018 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 Gene3D G3DSA:1.20.1110.10 63 355 1.8E-46 T 29-03-2018 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 SMART SM00831 12 85 8.3E-35 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CVS48_RS18545 f06606f5b44b6921ae35cdf54aa4662b 914 Pfam PF00122 E1-E2 ATPase 120 313 1.8E-50 T 29-03-2018 CVS48_RS03030 fff2eb66355999972582690d503f3e40 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 263 1.8E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS03030 fff2eb66355999972582690d503f3e40 293 Gene3D G3DSA:1.10.3470.10 3 267 3.0E-34 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS17560 38a2d436e662a88027a8069c4a116483 242 SUPERFAMILY SSF52172 3 129 1.34E-41 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS17560 38a2d436e662a88027a8069c4a116483 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 6.4E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS17560 38a2d436e662a88027a8069c4a116483 242 Gene3D G3DSA:1.10.10.10 125 236 6.0E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17560 38a2d436e662a88027a8069c4a116483 242 SUPERFAMILY SSF46894 128 232 4.54E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS17560 38a2d436e662a88027a8069c4a116483 242 SMART SM00448 5 116 5.1E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS17560 38a2d436e662a88027a8069c4a116483 242 Pfam PF00072 Response regulator receiver domain 7 116 9.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS17560 38a2d436e662a88027a8069c4a116483 242 Gene3D G3DSA:3.40.50.2300 1 124 8.6E-38 T 29-03-2018 CVS48_RS17560 38a2d436e662a88027a8069c4a116483 242 SMART SM00862 155 231 5.9E-30 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS06185 489dc8aa384deb4100f629e15e5e9f50 195 Gene3D G3DSA:2.60.120.10 2 191 3.0E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS06185 489dc8aa384deb4100f629e15e5e9f50 195 SUPERFAMILY SSF51182 13 189 1.57E-37 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS05870 12f0b52bb0e1202264278c7c3953921a 353 Pfam PF00005 ABC transporter 20 161 1.8E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05870 12f0b52bb0e1202264278c7c3953921a 353 SUPERFAMILY SSF50331 250 341 3.06E-9 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS05870 12f0b52bb0e1202264278c7c3953921a 353 Pfam PF08402 TOBE domain 272 341 8.8E-11 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS05870 12f0b52bb0e1202264278c7c3953921a 353 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05870 12f0b52bb0e1202264278c7c3953921a 353 Gene3D G3DSA:3.40.50.300 1 269 7.2E-75 T 29-03-2018 CVS48_RS05870 12f0b52bb0e1202264278c7c3953921a 353 SMART SM00382 28 211 2.1E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05870 12f0b52bb0e1202264278c7c3953921a 353 Gene3D G3DSA:2.40.50.140 275 337 3.9E-5 T 29-03-2018 CVS48_RS05870 12f0b52bb0e1202264278c7c3953921a 353 SUPERFAMILY SSF52540 4 241 4.69E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 7.3E-22 T 29-03-2018 CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 310 7.3E-22 T 29-03-2018 CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 7.3E-22 T 29-03-2018 CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 348 364 7.3E-22 T 29-03-2018 CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 326 7.3E-22 T 29-03-2018 CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 Gene3D G3DSA:3.50.50.60 1 366 2.3E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 Pfam PF01494 FAD binding domain 2 360 5.8E-29 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 SUPERFAMILY SSF51905 1 174 1.51E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 SUPERFAMILY SSF51905 282 370 1.51E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS28980 bae92dd160c01499abb997ee0b47b9da 421 SUPERFAMILY SSF54373 179 286 3.92E-32 T 29-03-2018 CVS48_RS24110 81e040a854ac9d99a9db652bea4fb047 373 SUPERFAMILY SSF50969 63 326 3.45E-16 T 29-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CVS48_RS24110 81e040a854ac9d99a9db652bea4fb047 373 PIRSF PIRSF028101 2 371 3.6E-110 T 29-03-2018 IPR008311 Uncharacterised conserved protein UCP028101 CVS48_RS24110 81e040a854ac9d99a9db652bea4fb047 373 Pfam PF07433 Protein of unknown function (DUF1513) 63 369 1.1E-111 T 29-03-2018 IPR008311 Uncharacterised conserved protein UCP028101 CVS48_RS24110 81e040a854ac9d99a9db652bea4fb047 373 Gene3D G3DSA:2.130.10.10 110 251 6.7E-11 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS24110 81e040a854ac9d99a9db652bea4fb047 373 Gene3D G3DSA:2.130.10.10 254 371 1.7E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS20670 7ff71764818a1f05e15e491f84be9a76 336 SUPERFAMILY SSF52172 2 120 1.99E-19 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS20670 7ff71764818a1f05e15e491f84be9a76 336 SUPERFAMILY SSF52738 151 334 1.06E-60 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS20670 7ff71764818a1f05e15e491f84be9a76 336 PIRSF PIRSF000876 1 336 2.7E-97 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS20670 7ff71764818a1f05e15e491f84be9a76 336 Pfam PF01339 CheB methylesterase 156 330 1.3E-55 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS20670 7ff71764818a1f05e15e491f84be9a76 336 SMART SM00448 1 116 3.5E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS20670 7ff71764818a1f05e15e491f84be9a76 336 Gene3D G3DSA:3.40.50.180 144 336 9.7E-68 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS20670 7ff71764818a1f05e15e491f84be9a76 336 Pfam PF00072 Response regulator receiver domain 4 103 2.1E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS20670 7ff71764818a1f05e15e491f84be9a76 336 Gene3D G3DSA:3.40.50.2300 1 128 1.1E-24 T 29-03-2018 CVS48_RS20670 7ff71764818a1f05e15e491f84be9a76 336 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 1 336 31.422 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 Pfam PF03466 LysR substrate binding domain 90 291 3.1E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.2E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 Gene3D G3DSA:3.40.190.10 88 174 9.5E-15 T 29-03-2018 CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 Gene3D G3DSA:3.40.190.10 175 269 1.2E-10 T 29-03-2018 CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 SUPERFAMILY SSF53850 90 295 5.43E-32 T 29-03-2018 CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 Gene3D G3DSA:1.10.10.10 1 86 9.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19670 086a8464d60fd35e06917847bb813dcd 301 SUPERFAMILY SSF46785 2 110 2.48E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09735 e3333c3850a6f565e4a30002a5779686 462 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 375 395 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CVS48_RS09735 e3333c3850a6f565e4a30002a5779686 462 Pfam PF00860 Permease family 37 428 2.5E-91 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS09735 e3333c3850a6f565e4a30002a5779686 462 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 34 455 2.6E-119 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CVS48_RS09735 e3333c3850a6f565e4a30002a5779686 462 TIGRFAM TIGR03173 pbuX: xanthine permease 40 459 6.1E-126 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CVS48_RS28745 4270dd62ab078b2fe2c031f61cf19e0d 609 Pfam PF01019 Gamma-glutamyltranspeptidase 28 600 3.2E-124 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS28745 4270dd62ab078b2fe2c031f61cf19e0d 609 SUPERFAMILY SSF56235 2 368 4.4E-145 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS28745 4270dd62ab078b2fe2c031f61cf19e0d 609 SUPERFAMILY SSF56235 414 600 4.4E-145 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS28745 4270dd62ab078b2fe2c031f61cf19e0d 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 473 488 5.4E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS28745 4270dd62ab078b2fe2c031f61cf19e0d 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 106 124 5.4E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS28745 4270dd62ab078b2fe2c031f61cf19e0d 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 5.4E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS28745 4270dd62ab078b2fe2c031f61cf19e0d 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 124 143 5.4E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS28745 4270dd62ab078b2fe2c031f61cf19e0d 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 497 514 5.4E-18 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS13480 231059a12739a89e110e579c484f08a3 250 PIRSF PIRSF039085 7 250 2.4E-104 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS13480 231059a12739a89e110e579c484f08a3 250 Gene3D G3DSA:3.40.50.300 7 249 2.9E-75 T 29-03-2018 CVS48_RS13480 231059a12739a89e110e579c484f08a3 250 Pfam PF00005 ABC transporter 26 174 6.8E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13480 231059a12739a89e110e579c484f08a3 250 SMART SM00382 35 222 1.7E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13480 231059a12739a89e110e579c484f08a3 250 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13480 231059a12739a89e110e579c484f08a3 250 SUPERFAMILY SSF52540 10 244 1.57E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20690 523afcd3f3e8ccdac0489cfe63133d0e 190 SUPERFAMILY SSF50341 21 175 3.92E-22 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS20690 523afcd3f3e8ccdac0489cfe63133d0e 190 Pfam PF01584 CheW-like domain 21 171 2.1E-21 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS20690 523afcd3f3e8ccdac0489cfe63133d0e 190 Gene3D G3DSA:2.40.50.180 37 143 1.2E-12 T 29-03-2018 CVS48_RS20690 523afcd3f3e8ccdac0489cfe63133d0e 190 SMART SM00260 16 171 4.5E-6 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS17370 0999c23d146750568bf650aa807a4993 233 Pfam PF00043 Glutathione S-transferase, C-terminal domain 111 196 4.2E-10 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS17370 0999c23d146750568bf650aa807a4993 233 SUPERFAMILY SSF47616 78 204 6.0E-39 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS17370 0999c23d146750568bf650aa807a4993 233 SUPERFAMILY SSF52833 1 84 3.37E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS17370 0999c23d146750568bf650aa807a4993 233 Gene3D G3DSA:3.40.30.10 1 93 1.4E-27 T 29-03-2018 CVS48_RS17370 0999c23d146750568bf650aa807a4993 233 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 81 3.8E-13 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS17370 0999c23d146750568bf650aa807a4993 233 Gene3D G3DSA:1.20.1050.10 147 200 2.2E-14 T 29-03-2018 CVS48_RS17370 0999c23d146750568bf650aa807a4993 233 Gene3D G3DSA:1.20.1050.10 94 146 2.7E-17 T 29-03-2018 CVS48_RS19850 c991a4ef8ca1fbd39953e8cdaa7a01da 124 Pfam PF00085 Thioredoxin 3 100 1.3E-25 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CVS48_RS19850 c991a4ef8ca1fbd39953e8cdaa7a01da 124 PRINTS PR00421 Thioredoxin family signature 68 79 4.7E-9 T 29-03-2018 CVS48_RS19850 c991a4ef8ca1fbd39953e8cdaa7a01da 124 PRINTS PR00421 Thioredoxin family signature 29 38 4.7E-9 T 29-03-2018 CVS48_RS19850 c991a4ef8ca1fbd39953e8cdaa7a01da 124 PRINTS PR00421 Thioredoxin family signature 21 29 4.7E-9 T 29-03-2018 CVS48_RS19850 c991a4ef8ca1fbd39953e8cdaa7a01da 124 PIRSF PIRSF000077 1 104 4.3E-28 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CVS48_RS19850 c991a4ef8ca1fbd39953e8cdaa7a01da 124 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CVS48_RS19850 c991a4ef8ca1fbd39953e8cdaa7a01da 124 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 1.3E-28 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CVS48_RS19850 c991a4ef8ca1fbd39953e8cdaa7a01da 124 Gene3D G3DSA:3.40.30.10 1 124 1.7E-32 T 29-03-2018 CVS48_RS19850 c991a4ef8ca1fbd39953e8cdaa7a01da 124 SUPERFAMILY SSF52833 2 105 2.76E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS05635 a23f48d809a5e87fdf1c273c60702896 323 SMART SM00342 218 301 1.0E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS05635 a23f48d809a5e87fdf1c273c60702896 323 Gene3D G3DSA:1.10.10.60 257 310 8.3E-13 T 29-03-2018 CVS48_RS05635 a23f48d809a5e87fdf1c273c60702896 323 Pfam PF12833 Helix-turn-helix domain 224 299 3.5E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS05635 a23f48d809a5e87fdf1c273c60702896 323 SUPERFAMILY SSF46689 202 252 8.58E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05635 a23f48d809a5e87fdf1c273c60702896 323 Gene3D G3DSA:1.10.10.60 190 256 7.0E-12 T 29-03-2018 CVS48_RS05635 a23f48d809a5e87fdf1c273c60702896 323 SUPERFAMILY SSF46689 255 305 2.02E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05635 a23f48d809a5e87fdf1c273c60702896 323 Pfam PF06719 AraC-type transcriptional regulator N-terminus 39 189 5.7E-40 T 29-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal CVS48_RS07450 133a0cbdb9f28ea8839a68fd9873b662 224 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 15 198 2.7E-26 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CVS48_RS07450 133a0cbdb9f28ea8839a68fd9873b662 224 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 14 199 5.2E-37 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CVS48_RS07450 133a0cbdb9f28ea8839a68fd9873b662 224 SUPERFAMILY SSF100950 13 203 1.53E-41 T 29-03-2018 CVS48_RS07450 133a0cbdb9f28ea8839a68fd9873b662 224 Gene3D G3DSA:3.40.50.10420 2 208 2.3E-49 T 29-03-2018 CVS48_RS07605 1a2480cc96f78916b90fd5c5770080a6 232 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 232 33.674 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS07605 1a2480cc96f78916b90fd5c5770080a6 232 Pfam PF00156 Phosphoribosyl transferase domain 50 178 1.4E-16 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CVS48_RS07605 1a2480cc96f78916b90fd5c5770080a6 232 Gene3D G3DSA:3.40.50.2020 10 211 2.3E-48 T 29-03-2018 CVS48_RS07605 1a2480cc96f78916b90fd5c5770080a6 232 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 20 205 1.7E-59 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS07605 1a2480cc96f78916b90fd5c5770080a6 232 SUPERFAMILY SSF53271 13 229 9.57E-46 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CVS48_RS17250 620a84f52eb1917cc40b66c5a72a9548 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 1.6E-34 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CVS48_RS17250 620a84f52eb1917cc40b66c5a72a9548 144 Gene3D G3DSA:3.30.530.20 1 144 1.4E-34 T 29-03-2018 IPR023393 START-like domain CVS48_RS17250 620a84f52eb1917cc40b66c5a72a9548 144 SUPERFAMILY SSF55961 1 143 1.45E-38 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Pfam PF01909 Nucleotidyltransferase domain 55 119 3.3E-6 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Gene3D G3DSA:3.30.460.10 15 158 2.9E-25 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 SUPERFAMILY SSF81301 31 153 3.02E-22 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Pfam PF01842 ACT domain 793 837 3.4E-7 T 29-03-2018 IPR002912 ACT domain CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 SUPERFAMILY SSF81593 169 290 4.87E-8 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 19 858 1.5E-230 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 868 308.943 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Pfam PF08335 GlnD PII-uridylyltransferase 162 300 6.4E-30 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Gene3D G3DSA:3.30.70.260 785 866 1.9E-14 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Gene3D G3DSA:3.30.70.260 670 754 2.2E-6 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Gene3D G3DSA:1.10.3090.10 329 610 1.4E-38 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 SUPERFAMILY SSF55021 672 729 2.75E-8 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 SUPERFAMILY SSF109604 406 528 1.47E-16 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 SMART SM00471 433 580 5.6E-7 T 29-03-2018 IPR003607 HD/PDEase domain CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 PIRSF PIRSF006288 1 866 0.0 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Gene3D G3DSA:1.20.120.330 160 305 1.3E-23 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 SUPERFAMILY SSF55021 789 851 6.7E-11 T 29-03-2018 CVS48_RS17110 6bcd71b1ea3502b88cad0845dd5d9b98 868 Pfam PF01966 HD domain 438 540 5.6E-9 T 29-03-2018 IPR006674 HD domain CVS48_RS17855 946ac0d5a73dbebd0eb819dd1dfd9ca9 299 Gene3D G3DSA:3.40.190.10 79 182 7.5E-12 T 29-03-2018 CVS48_RS17855 946ac0d5a73dbebd0eb819dd1dfd9ca9 299 Gene3D G3DSA:3.40.190.10 183 261 1.5E-15 T 29-03-2018 CVS48_RS17855 946ac0d5a73dbebd0eb819dd1dfd9ca9 299 Pfam PF03466 LysR substrate binding domain 88 280 2.8E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17855 946ac0d5a73dbebd0eb819dd1dfd9ca9 299 Gene3D G3DSA:1.10.10.10 1 78 1.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17855 946ac0d5a73dbebd0eb819dd1dfd9ca9 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.5E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17855 946ac0d5a73dbebd0eb819dd1dfd9ca9 299 SUPERFAMILY SSF46785 1 83 1.84E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17855 946ac0d5a73dbebd0eb819dd1dfd9ca9 299 SUPERFAMILY SSF53850 87 280 3.48E-36 T 29-03-2018 CVS48_RS25915 79adb659a4fc5cad4f926909b24c61af 416 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS25915 79adb659a4fc5cad4f926909b24c61af 416 Pfam PF00005 ABC transporter 43 191 1.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS25915 79adb659a4fc5cad4f926909b24c61af 416 SUPERFAMILY SSF54631 275 391 2.07E-11 T 29-03-2018 CVS48_RS25915 79adb659a4fc5cad4f926909b24c61af 416 Gene3D G3DSA:3.40.50.300 1 283 7.7E-73 T 29-03-2018 CVS48_RS25915 79adb659a4fc5cad4f926909b24c61af 416 SUPERFAMILY SSF52540 39 270 1.03E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS25915 79adb659a4fc5cad4f926909b24c61af 416 SMART SM00382 52 240 5.1E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS25915 79adb659a4fc5cad4f926909b24c61af 416 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 388 5.4E-124 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CVS48_RS25915 79adb659a4fc5cad4f926909b24c61af 416 Gene3D G3DSA:3.10.580.10 284 391 2.4E-10 T 29-03-2018 CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 SUPERFAMILY SSF52540 6 262 1.16E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 544 593 3.1E-10 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 SMART SM00382 35 240 2.7E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 SMART SM00382 352 544 6.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 ProSitePatterns PS00211 ABC transporters family signature. 467 481 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 Pfam PF00005 ABC transporter 27 190 2.8E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 Pfam PF00005 ABC transporter 344 493 1.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 546 578 5.7E-9 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 272 9.0E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 SUPERFAMILY SSF52540 317 566 2.38E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 Gene3D G3DSA:3.40.50.300 3 292 1.6E-68 T 29-03-2018 CVS48_RS16260 ac5c95851fdf949a16304143112d2f5c 622 Gene3D G3DSA:3.40.50.300 313 597 5.6E-72 T 29-03-2018 CVS48_RS21425 73d86adc96490f7ee8c232b6e8e7c448 179 SUPERFAMILY SSF54593 8 146 4.37E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS21425 73d86adc96490f7ee8c232b6e8e7c448 179 Gene3D G3DSA:3.10.180.10 3 162 2.4E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS21425 73d86adc96490f7ee8c232b6e8e7c448 179 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 5.0E-32 T 29-03-2018 CVS48_RS22195 be670365b868b8434b7c135257f73247 162 Gene3D G3DSA:1.10.1740.10 2 69 7.4E-15 T 29-03-2018 CVS48_RS22195 be670365b868b8434b7c135257f73247 162 SUPERFAMILY SSF88946 6 86 2.51E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS22195 be670365b868b8434b7c135257f73247 162 SUPERFAMILY SSF88659 85 160 1.29E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS22195 be670365b868b8434b7c135257f73247 162 Pfam PF04542 Sigma-70 region 2 8 73 5.8E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS22195 be670365b868b8434b7c135257f73247 162 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 154 1.7E-18 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS22195 be670365b868b8434b7c135257f73247 162 Pfam PF08281 Sigma-70, region 4 105 156 1.6E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS22195 be670365b868b8434b7c135257f73247 162 Gene3D G3DSA:1.10.10.10 70 162 2.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 9.7E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 Pfam PF07729 FCD domain 87 209 1.6E-26 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 SUPERFAMILY SSF46785 11 81 1.05E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 SUPERFAMILY SSF48008 85 219 4.71E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 2.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 2.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 SMART SM00345 19 77 6.0E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 Gene3D G3DSA:1.20.120.530 80 229 7.1E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 SMART SM00895 87 211 6.0E-18 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS08735 a833522e14f7debc1bb175bac1de831b 247 Gene3D G3DSA:1.10.10.10 7 79 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 Pfam PF02779 Transketolase, pyrimidine binding domain 316 474 6.7E-38 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 Pfam PF02780 Transketolase, C-terminal domain 491 607 5.3E-28 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 ProSitePatterns PS00801 Transketolase signature 1. 31 50 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 5 616 45.667 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 8 613 1.6E-260 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 SUPERFAMILY SSF52518 307 475 1.55E-57 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 SMART SM00861 315 479 5.8E-61 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 SUPERFAMILY SSF52922 487 613 2.88E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 SUPERFAMILY SSF52518 3 345 2.49E-77 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 Gene3D G3DSA:3.40.50.970 294 481 9.6E-62 T 29-03-2018 CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 6 278 1.2E-120 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 Gene3D G3DSA:3.40.50.920 491 616 2.0E-35 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS27015 e67e272606cf9a816d333ce1e8dac900 620 Gene3D G3DSA:3.40.50.970 1 293 2.4E-81 T 29-03-2018 CVS48_RS01105 f5fa479dd0e5e3a2bf9307d38bae0375 205 Pfam PF04268 Sarcosine oxidase, gamma subunit family 43 194 8.4E-25 T 29-03-2018 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CVS48_RS01105 f5fa479dd0e5e3a2bf9307d38bae0375 205 Gene3D G3DSA:3.30.70.1520 36 111 2.7E-17 T 29-03-2018 CVS48_RS01105 f5fa479dd0e5e3a2bf9307d38bae0375 205 SUPERFAMILY SSF103025 77 195 3.34E-16 T 29-03-2018 CVS48_RS01105 f5fa479dd0e5e3a2bf9307d38bae0375 205 Gene3D G3DSA:3.30.1360.120 112 198 9.1E-8 T 29-03-2018 CVS48_RS09455 f5c7ee640fa689cb1258377cdaec2a09 360 SUPERFAMILY SSF53850 90 297 1.41E-42 T 29-03-2018 CVS48_RS09455 f5c7ee640fa689cb1258377cdaec2a09 360 SUPERFAMILY SSF46785 4 84 1.41E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09455 f5c7ee640fa689cb1258377cdaec2a09 360 Gene3D G3DSA:3.40.190.10 176 265 1.3E-24 T 29-03-2018 CVS48_RS09455 f5c7ee640fa689cb1258377cdaec2a09 360 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.0E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09455 f5c7ee640fa689cb1258377cdaec2a09 360 Gene3D G3DSA:3.40.190.10 89 175 2.6E-11 T 29-03-2018 CVS48_RS09455 f5c7ee640fa689cb1258377cdaec2a09 360 Pfam PF03466 LysR substrate binding domain 90 294 1.5E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS09455 f5c7ee640fa689cb1258377cdaec2a09 360 Gene3D G3DSA:1.10.10.10 3 83 1.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10875 715b1bd1b5d7206599046907b7c87652 203 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 94 1.0E-36 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CVS48_RS10875 715b1bd1b5d7206599046907b7c87652 203 Pfam PF01386 Ribosomal L25p family 5 91 3.7E-23 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CVS48_RS10875 715b1bd1b5d7206599046907b7c87652 203 Gene3D G3DSA:2.170.120.20 98 193 1.9E-23 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain CVS48_RS10875 715b1bd1b5d7206599046907b7c87652 203 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 185 29.34 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CVS48_RS10875 715b1bd1b5d7206599046907b7c87652 203 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 172 1.4E-38 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CVS48_RS10875 715b1bd1b5d7206599046907b7c87652 203 Gene3D G3DSA:2.40.240.10 1 94 8.1E-28 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CVS48_RS10875 715b1bd1b5d7206599046907b7c87652 203 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 94 22.842 T 29-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CVS48_RS10875 715b1bd1b5d7206599046907b7c87652 203 SUPERFAMILY SSF50715 2 190 1.41E-50 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CVS48_RS10875 715b1bd1b5d7206599046907b7c87652 203 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 174 3.7E-24 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain CVS48_RS24960 dd132aefcdb45d918072f84f7ce58e47 603 Gene3D G3DSA:2.40.160.50 223 603 7.1E-46 T 29-03-2018 CVS48_RS24960 dd132aefcdb45d918072f84f7ce58e47 603 Pfam PF08479 POTRA domain, ShlB-type 120 193 1.0E-16 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type CVS48_RS24960 dd132aefcdb45d918072f84f7ce58e47 603 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 255 563 7.4E-35 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal CVS48_RS24960 dd132aefcdb45d918072f84f7ce58e47 603 Gene3D G3DSA:3.10.20.310 125 193 1.1E-15 T 29-03-2018 CVS48_RS01270 2b2bf71abb5bb9ca53a15abe8c236259 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 57 5.2E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01270 2b2bf71abb5bb9ca53a15abe8c236259 304 Gene3D G3DSA:1.10.10.10 1 78 3.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01270 2b2bf71abb5bb9ca53a15abe8c236259 304 SUPERFAMILY SSF46785 4 106 9.58E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01270 2b2bf71abb5bb9ca53a15abe8c236259 304 Gene3D G3DSA:3.40.190.10 82 169 2.9E-17 T 29-03-2018 CVS48_RS01270 2b2bf71abb5bb9ca53a15abe8c236259 304 Pfam PF03466 LysR substrate binding domain 82 286 2.3E-54 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS01270 2b2bf71abb5bb9ca53a15abe8c236259 304 Gene3D G3DSA:3.40.190.10 170 257 3.4E-31 T 29-03-2018 CVS48_RS01270 2b2bf71abb5bb9ca53a15abe8c236259 304 SUPERFAMILY SSF53850 83 289 4.71E-56 T 29-03-2018 CVS48_RS14990 d98fce20609cb611e111cf5ded9ff4f4 364 Gene3D G3DSA:3.40.190.10 162 340 3.6E-5 T 29-03-2018 CVS48_RS14990 d98fce20609cb611e111cf5ded9ff4f4 364 SUPERFAMILY SSF53850 164 318 1.75E-7 T 29-03-2018 CVS48_RS14990 d98fce20609cb611e111cf5ded9ff4f4 364 PIRSF PIRSF039026 1 356 1.6E-105 T 29-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CVS48_RS14990 d98fce20609cb611e111cf5ded9ff4f4 364 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 42 323 2.3E-47 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS06160 6855d40fd2b1749e2fc33ba9ac6ff917 266 PIRSF PIRSF009320 95 263 5.4E-10 T 29-03-2018 CVS48_RS06160 6855d40fd2b1749e2fc33ba9ac6ff917 266 PIRSF PIRSF009320 10 92 4.5E-14 T 29-03-2018 CVS48_RS06160 6855d40fd2b1749e2fc33ba9ac6ff917 266 SUPERFAMILY SSF52540 10 262 1.91E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06160 6855d40fd2b1749e2fc33ba9ac6ff917 266 Gene3D G3DSA:3.40.50.300 9 266 9.9E-60 T 29-03-2018 CVS48_RS06160 6855d40fd2b1749e2fc33ba9ac6ff917 266 Pfam PF13614 AAA domain 11 185 4.1E-66 T 29-03-2018 IPR025669 AAA domain CVS48_RS09340 223f36dd44ffad9c7b86b60cf77ec6a9 181 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 4 178 17.109 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CVS48_RS09340 223f36dd44ffad9c7b86b60cf77ec6a9 181 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 4 175 5.9E-32 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CVS48_RS09340 223f36dd44ffad9c7b86b60cf77ec6a9 181 SUPERFAMILY SSF55144 4 175 4.36E-36 T 29-03-2018 IPR009097 Cyclic phosphodiesterase CVS48_RS09340 223f36dd44ffad9c7b86b60cf77ec6a9 181 Gene3D G3DSA:3.90.1140.10 4 181 1.2E-30 T 29-03-2018 CVS48_RS09340 223f36dd44ffad9c7b86b60cf77ec6a9 181 Pfam PF02834 LigT like Phosphoesterase 11 88 4.3E-11 T 29-03-2018 IPR014051 Phosphoesterase, HXTX CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 Gene3D G3DSA:1.10.10.10 1 84 8.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 SUPERFAMILY SSF46785 1 87 2.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 Pfam PF03466 LysR substrate binding domain 88 287 3.5E-19 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 SUPERFAMILY SSF53850 84 290 4.54E-20 T 29-03-2018 CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 Gene3D G3DSA:3.40.190.10 85 177 1.6E-10 T 29-03-2018 CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.3E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.3E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.3E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13810 443b25c0b6ded63e05714bde27abf4e1 302 Gene3D G3DSA:3.40.190.10 178 259 6.6E-14 T 29-03-2018 CVS48_RS22170 509d4fd2b26fe664fa57c5a82718ae2b 404 Gene3D G3DSA:3.40.640.10 50 281 3.0E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS22170 509d4fd2b26fe664fa57c5a82718ae2b 404 SUPERFAMILY SSF53383 6 400 2.2E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS22170 509d4fd2b26fe664fa57c5a82718ae2b 404 Pfam PF00155 Aminotransferase class I and II 39 395 8.1E-46 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS22170 509d4fd2b26fe664fa57c5a82718ae2b 404 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 7 400 4.1E-185 T 29-03-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 CVS48_RS22170 509d4fd2b26fe664fa57c5a82718ae2b 404 Gene3D G3DSA:3.90.1150.10 282 401 3.5E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 Gene3D G3DSA:3.50.50.60 175 364 3.6E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 Pfam PF04324 BFD-like [2Fe-2S] binding domain 384 436 6.9E-9 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 326 1.9E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 9.9E-15 T 29-03-2018 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 9.9E-15 T 29-03-2018 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 9.9E-15 T 29-03-2018 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 9.9E-15 T 29-03-2018 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 PIRSF PIRSF037495 1 474 4.5E-162 T 29-03-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.3E-11 T 29-03-2018 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 120 129 1.3E-11 T 29-03-2018 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 1.3E-11 T 29-03-2018 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 SUPERFAMILY SSF51905 4 316 2.93E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 Gene3D G3DSA:3.50.50.60 122 166 7.0E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05845 54421890efea7ae18df2bba8c07c96ce 480 Gene3D G3DSA:3.50.50.60 1 121 3.0E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS02340 08d403e827df6eace7641ae3efd34996 624 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 118 236 1.0E-20 T 29-03-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 CVS48_RS02340 08d403e827df6eace7641ae3efd34996 624 Gene3D G3DSA:3.30.9.10 426 565 2.0E-20 T 29-03-2018 CVS48_RS02340 08d403e827df6eace7641ae3efd34996 624 Pfam PF01266 FAD dependent oxidoreductase 255 602 1.1E-32 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS02340 08d403e827df6eace7641ae3efd34996 624 Gene3D G3DSA:3.40.50.150 11 235 1.7E-52 T 29-03-2018 CVS48_RS02340 08d403e827df6eace7641ae3efd34996 624 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 255 623 4.3E-60 T 29-03-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 CVS48_RS02340 08d403e827df6eace7641ae3efd34996 624 Gene3D G3DSA:3.50.50.60 236 425 1.6E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS02340 08d403e827df6eace7641ae3efd34996 624 SUPERFAMILY SSF51905 566 612 1.29E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS02340 08d403e827df6eace7641ae3efd34996 624 SUPERFAMILY SSF51905 255 466 1.29E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS02340 08d403e827df6eace7641ae3efd34996 624 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 9 624 19.11 T 29-03-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 CVS48_RS12655 077fe070ffeb49fceea3ad6bfb350ac0 417 SUPERFAMILY SSF53822 31 410 7.33E-90 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS12655 077fe070ffeb49fceea3ad6bfb350ac0 417 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 32 405 5.6E-179 T 29-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like CVS48_RS12655 077fe070ffeb49fceea3ad6bfb350ac0 417 Pfam PF13433 Periplasmic binding protein domain 32 408 7.2E-172 T 29-03-2018 CVS48_RS12655 077fe070ffeb49fceea3ad6bfb350ac0 417 Gene3D G3DSA:3.40.50.2300 202 379 9.3E-21 T 29-03-2018 CVS48_RS12655 077fe070ffeb49fceea3ad6bfb350ac0 417 Gene3D G3DSA:3.40.50.2300 28 201 2.5E-25 T 29-03-2018 CVS48_RS12160 29a4333dcdb70ebb92b335efd5e7e913 263 SUPERFAMILY SSF53335 11 210 2.99E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS12160 29a4333dcdb70ebb92b335efd5e7e913 263 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 8 261 40.747 T 29-03-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CVS48_RS12160 29a4333dcdb70ebb92b335efd5e7e913 263 Pfam PF13847 Methyltransferase domain 40 147 8.8E-16 T 29-03-2018 IPR025714 Methyltransferase domain CVS48_RS12160 29a4333dcdb70ebb92b335efd5e7e913 263 Gene3D G3DSA:3.40.50.150 18 184 1.4E-28 T 29-03-2018 CVS48_RS12160 29a4333dcdb70ebb92b335efd5e7e913 263 Gene3D G3DSA:1.10.150.290 185 240 2.8E-28 T 29-03-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CVS48_RS20790 9811bd741c8e55e537a97829b9137faa 146 SUPERFAMILY SSF49764 25 145 4.71E-31 T 29-03-2018 IPR008978 HSP20-like chaperone CVS48_RS20790 9811bd741c8e55e537a97829b9137faa 146 Gene3D G3DSA:2.60.40.790 6 146 2.1E-27 T 29-03-2018 IPR008978 HSP20-like chaperone CVS48_RS20790 9811bd741c8e55e537a97829b9137faa 146 Pfam PF00011 Hsp20/alpha crystallin family 52 146 3.0E-19 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CVS48_RS09860 18ebccea3ce84a9b1b21ef9c290780b1 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 2.0E-24 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis CVS48_RS09860 18ebccea3ce84a9b1b21ef9c290780b1 66 SUPERFAMILY SSF54285 3 65 5.23E-20 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CVS48_RS09860 18ebccea3ce84a9b1b21ef9c290780b1 66 Gene3D G3DSA:3.10.20.30 1 66 1.5E-24 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS09860 18ebccea3ce84a9b1b21ef9c290780b1 66 Pfam PF02597 ThiS family 3 66 1.1E-16 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 Gene3D G3DSA:3.40.120.10 276 378 1.1E-26 T 29-03-2018 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 SUPERFAMILY SSF53738 264 371 3.06E-29 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 SUPERFAMILY SSF53738 2 187 2.43E-48 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 SUPERFAMILY SSF53738 162 262 9.42E-28 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 260 6.2E-17 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 444 6.4E-175 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 Gene3D G3DSA:3.40.120.10 3 160 8.1E-50 T 29-03-2018 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 371 6.8E-29 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 446 1.7E-13 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 102 111 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 445 44.996 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 SUPERFAMILY SSF55957 363 445 1.96E-19 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 Gene3D G3DSA:3.40.120.10 162 275 2.2E-28 T 29-03-2018 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 140 8.7E-43 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 Gene3D G3DSA:3.30.310.50 379 447 1.3E-17 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 255 6.4E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 101 115 6.4E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS13865 010e69faf569b3ce612d5799c8ff1e20 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 6.4E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS26985 087075dad5137aa5f9ac434b7871312c 151 SUPERFAMILY SSF55658 1 56 4.88E-18 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CVS48_RS26985 087075dad5137aa5f9ac434b7871312c 151 Gene3D G3DSA:3.10.430.100 63 148 2.7E-24 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CVS48_RS26985 087075dad5137aa5f9ac434b7871312c 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.791 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS26985 087075dad5137aa5f9ac434b7871312c 151 SUPERFAMILY SSF55653 59 148 2.49E-23 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CVS48_RS26985 087075dad5137aa5f9ac434b7871312c 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26985 087075dad5137aa5f9ac434b7871312c 151 Gene3D G3DSA:3.40.5.10 1 49 2.5E-22 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26985 087075dad5137aa5f9ac434b7871312c 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 4.5E-25 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CVS48_RS26985 087075dad5137aa5f9ac434b7871312c 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 2.0E-21 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS26985 087075dad5137aa5f9ac434b7871312c 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.4E-42 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS04805 356c160aeb5f8542bb84ed2563d0b1b8 373 Gene3D G3DSA:1.10.3470.10 25 343 1.9E-25 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS04805 356c160aeb5f8542bb84ed2563d0b1b8 373 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 338 1.5E-32 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS04805 356c160aeb5f8542bb84ed2563d0b1b8 373 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 30 348 2.7E-132 T 29-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC CVS48_RS21170 73677063a3c84f70992a3185b8c0c14e 213 Gene3D G3DSA:1.20.1050.10 98 213 1.6E-22 T 29-03-2018 CVS48_RS21170 73677063a3c84f70992a3185b8c0c14e 213 SUPERFAMILY SSF47616 85 206 6.26E-25 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS21170 73677063a3c84f70992a3185b8c0c14e 213 Gene3D G3DSA:3.40.30.10 1 97 5.4E-20 T 29-03-2018 CVS48_RS21170 73677063a3c84f70992a3185b8c0c14e 213 SUPERFAMILY SSF52833 2 78 4.58E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS21170 73677063a3c84f70992a3185b8c0c14e 213 Pfam PF13417 Glutathione S-transferase, N-terminal domain 12 79 5.5E-12 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS21170 73677063a3c84f70992a3185b8c0c14e 213 Pfam PF00043 Glutathione S-transferase, C-terminal domain 121 194 2.6E-7 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS21050 d9eb74a928c3fcda8d62c637a5495d8a 287 Pfam PF13679 Methyltransferase domain 35 179 4.7E-44 T 29-03-2018 IPR025714 Methyltransferase domain CVS48_RS21050 d9eb74a928c3fcda8d62c637a5495d8a 287 Gene3D G3DSA:3.40.50.150 28 261 1.8E-6 T 29-03-2018 CVS48_RS21050 d9eb74a928c3fcda8d62c637a5495d8a 287 SUPERFAMILY SSF53335 42 189 1.22E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS03825 7eaa6033447efe2eb74866acbb885e4f 289 SUPERFAMILY SSF52402 146 284 1.34E-25 T 29-03-2018 CVS48_RS03825 7eaa6033447efe2eb74866acbb885e4f 289 PRINTS PR01438 Universal stress protein signature 148 166 2.7E-13 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS03825 7eaa6033447efe2eb74866acbb885e4f 289 PRINTS PR01438 Universal stress protein signature 244 256 2.7E-13 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS03825 7eaa6033447efe2eb74866acbb885e4f 289 PRINTS PR01438 Universal stress protein signature 262 284 2.7E-13 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS03825 7eaa6033447efe2eb74866acbb885e4f 289 Gene3D G3DSA:3.40.50.620 145 289 1.1E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS03825 7eaa6033447efe2eb74866acbb885e4f 289 Pfam PF00582 Universal stress protein family 7 141 8.6E-28 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS03825 7eaa6033447efe2eb74866acbb885e4f 289 Pfam PF00582 Universal stress protein family 148 284 2.6E-21 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS03825 7eaa6033447efe2eb74866acbb885e4f 289 SUPERFAMILY SSF52402 7 143 3.6E-29 T 29-03-2018 CVS48_RS03825 7eaa6033447efe2eb74866acbb885e4f 289 Gene3D G3DSA:3.40.50.620 1 144 3.0E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS11950 d4373a3ff9f2517acb0bb6b477cbf467 222 SUPERFAMILY SSF46894 125 217 3.12E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS11950 d4373a3ff9f2517acb0bb6b477cbf467 222 SMART SM00448 1 112 7.2E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS11950 d4373a3ff9f2517acb0bb6b477cbf467 222 Pfam PF00072 Response regulator receiver domain 3 112 1.4E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS11950 d4373a3ff9f2517acb0bb6b477cbf467 222 Gene3D G3DSA:1.10.10.10 119 221 1.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11950 d4373a3ff9f2517acb0bb6b477cbf467 222 Gene3D G3DSA:3.40.50.2300 1 118 1.6E-32 T 29-03-2018 CVS48_RS11950 d4373a3ff9f2517acb0bb6b477cbf467 222 SMART SM00862 145 216 1.3E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS11950 d4373a3ff9f2517acb0bb6b477cbf467 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 1.4E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS11950 d4373a3ff9f2517acb0bb6b477cbf467 222 SUPERFAMILY SSF52172 2 120 5.12E-34 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS08530 00434e8f7b579ec63abb2a85312648c2 818 Gene3D G3DSA:2.40.50.260 403 520 4.3E-18 T 29-03-2018 CVS48_RS08530 00434e8f7b579ec63abb2a85312648c2 818 SUPERFAMILY SSF69255 411 497 1.26E-16 T 29-03-2018 CVS48_RS08530 00434e8f7b579ec63abb2a85312648c2 818 Gene3D G3DSA:3.55.50.10 105 207 7.9E-14 T 29-03-2018 CVS48_RS08530 00434e8f7b579ec63abb2a85312648c2 818 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 30 504 4.5E-58 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein CVS48_RS08530 00434e8f7b579ec63abb2a85312648c2 818 Pfam PF05954 Phage late control gene D protein (GPD) 36 354 2.4E-42 T 29-03-2018 CVS48_RS08530 00434e8f7b579ec63abb2a85312648c2 818 SUPERFAMILY SSF69279 227 397 7.99E-12 T 29-03-2018 CVS48_RS08530 00434e8f7b579ec63abb2a85312648c2 818 SUPERFAMILY SSF69279 24 203 2.35E-35 T 29-03-2018 CVS48_RS10390 566234c285393602dd4296b1ea364da0 325 Gene3D G3DSA:3.40.190.10 34 235 6.1E-12 T 29-03-2018 CVS48_RS10390 566234c285393602dd4296b1ea364da0 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 4.8E-89 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS10390 566234c285393602dd4296b1ea364da0 325 PIRSF PIRSF017082 1 325 1.1E-79 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS10390 566234c285393602dd4296b1ea364da0 325 SUPERFAMILY SSF53850 110 285 2.02E-13 T 29-03-2018 CVS48_RS08385 780a70aa28614395d2af60f77b60d63f 442 Pfam PF06864 Pilin accessory protein (PilO) 21 440 8.1E-78 T 29-03-2018 IPR009663 Pilin accessory predicted CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 Gene3D G3DSA:3.30.590.10 106 458 8.6E-122 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 SMART SM01230 103 380 7.0E-150 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 SUPERFAMILY SSF55931 103 469 1.86E-139 T 29-03-2018 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 Pfam PF00120 Glutamine synthetase, catalytic domain 104 467 2.9E-139 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 469 2.2E-198 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 96 2.1E-29 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 Gene3D G3DSA:3.10.20.70 3 105 1.6E-26 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 260 275 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 387 399 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS19480 7dfef00849ee84555339aae436cd182d 470 SUPERFAMILY SSF54368 4 98 4.32E-34 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CVS48_RS07455 0187e2fbcf9a934c55e4d4e4d1328339 712 Gene3D G3DSA:1.25.20.10 92 447 5.1E-35 T 29-03-2018 CVS48_RS07455 0187e2fbcf9a934c55e4d4e4d1328339 712 Gene3D G3DSA:1.10.530.10 526 693 2.0E-29 T 29-03-2018 CVS48_RS07455 0187e2fbcf9a934c55e4d4e4d1328339 712 SUPERFAMILY SSF48435 95 535 2.35E-97 T 29-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 CVS48_RS07455 0187e2fbcf9a934c55e4d4e4d1328339 712 SUPERFAMILY SSF53955 542 698 8.55E-43 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS07455 0187e2fbcf9a934c55e4d4e4d1328339 712 Pfam PF14718 Soluble lytic murein transglycosylase L domain 466 525 9.1E-9 T 29-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 CVS48_RS07455 0187e2fbcf9a934c55e4d4e4d1328339 712 Gene3D G3DSA:1.10.1240.20 463 525 1.2E-21 T 29-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 CVS48_RS07455 0187e2fbcf9a934c55e4d4e4d1328339 712 Pfam PF01464 Transglycosylase SLT domain 545 650 8.1E-20 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CVS48_RS01600 9badc1222071120a16c168ec2b471934 261 SUPERFAMILY SSF102198 20 257 1.7E-52 T 29-03-2018 CVS48_RS01600 9badc1222071120a16c168ec2b471934 261 Pfam PF04199 Putative cyclase 21 197 4.0E-31 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CVS48_RS01600 9badc1222071120a16c168ec2b471934 261 Gene3D G3DSA:3.50.30.50 16 261 1.3E-50 T 29-03-2018 CVS48_RS22280 c82e438ac64f24fbffe644df3fb14bf6 346 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 177 2.1E-28 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 161 1.9E-55 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 Pfam PF01327 Polypeptide deformylase 5 153 3.9E-51 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 Hamap MF_00163 Peptide deformylase [def]. 2 163 31.071 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 PRINTS PR01576 Peptide deformylase signature 33 62 2.0E-36 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 PRINTS PR01576 Peptide deformylase signature 121 150 2.0E-36 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 PRINTS PR01576 Peptide deformylase signature 102 120 2.0E-36 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 PRINTS PR01576 Peptide deformylase signature 90 101 2.0E-36 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 PIRSF PIRSF004749 1 170 1.9E-56 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 Gene3D G3DSA:3.90.45.10 1 169 9.4E-64 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS07885 90228dadfafc32a823b9da65d851dd42 170 SUPERFAMILY SSF56420 2 164 7.46E-63 T 29-03-2018 IPR023635 Peptide deformylase CVS48_RS23650 49f495d8af2f6a35e1374873fd29962b 182 SMART SM00347 50 150 4.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS23650 49f495d8af2f6a35e1374873fd29962b 182 Pfam PF12802 MarR family 55 113 2.4E-9 T 29-03-2018 CVS48_RS23650 49f495d8af2f6a35e1374873fd29962b 182 SUPERFAMILY SSF46785 32 164 5.55E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23650 49f495d8af2f6a35e1374873fd29962b 182 Gene3D G3DSA:1.10.10.10 8 169 2.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 392 406 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 611 735 1.9E-45 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 SUPERFAMILY SSF55904 606 749 8.63E-44 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 Gene3D G3DSA:3.90.100.10 635 753 3.0E-33 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 Gene3D G3DSA:3.40.640.10 151 458 2.3E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 Gene3D G3DSA:3.90.1150.10 459 634 2.9E-74 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 145 4.9E-38 T 29-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 PIRSF PIRSF009393 1 753 2.9E-276 T 29-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 151 584 2.1E-152 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CVS48_RS10560 44ea6c0e7bcef199d50551719625b71c 753 SUPERFAMILY SSF53383 151 604 4.57E-116 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS17140 59e80c41e47a38c07cdbf84d3b2ecd03 254 Gene3D G3DSA:3.40.1180.10 1 246 2.2E-89 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CVS48_RS17140 59e80c41e47a38c07cdbf84d3b2ecd03 254 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 15 242 5.4E-86 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CVS48_RS17140 59e80c41e47a38c07cdbf84d3b2ecd03 254 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 188 205 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CVS48_RS17140 59e80c41e47a38c07cdbf84d3b2ecd03 254 SUPERFAMILY SSF64005 12 238 3.66E-84 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CVS48_RS17140 59e80c41e47a38c07cdbf84d3b2ecd03 254 Pfam PF01255 Putative undecaprenyl diphosphate synthase 22 242 3.1E-78 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CVS48_RS17140 59e80c41e47a38c07cdbf84d3b2ecd03 254 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 15 243 39.361 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CVS48_RS03325 ca86697d3230a913731449d3d03f89f7 133 Gene3D G3DSA:3.30.420.140 2 133 8.1E-37 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CVS48_RS03325 ca86697d3230a913731449d3d03f89f7 133 SMART SM00732 4 104 7.6E-29 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CVS48_RS03325 ca86697d3230a913731449d3d03f89f7 133 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 131 21.263 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CVS48_RS03325 ca86697d3230a913731449d3d03f89f7 133 SUPERFAMILY SSF53098 5 130 2.88E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS03325 ca86697d3230a913731449d3d03f89f7 133 Pfam PF03652 Holliday junction resolvase 5 129 6.6E-35 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CVS48_RS03325 ca86697d3230a913731449d3d03f89f7 133 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 128 1.3E-27 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CVS48_RS14125 8d00530e5d61e391e01f2cd47003088e 234 Gene3D G3DSA:3.40.50.300 1 233 7.9E-58 T 29-03-2018 CVS48_RS14125 8d00530e5d61e391e01f2cd47003088e 234 SMART SM00382 26 213 1.1E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS14125 8d00530e5d61e391e01f2cd47003088e 234 SUPERFAMILY SSF52540 2 232 3.04E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14125 8d00530e5d61e391e01f2cd47003088e 234 Pfam PF00005 ABC transporter 17 162 2.8E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS14125 8d00530e5d61e391e01f2cd47003088e 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS02410 2fed0f80d0db5367e493af7ead1ecc26 251 Pfam PF07729 FCD domain 90 211 1.8E-24 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS02410 2fed0f80d0db5367e493af7ead1ecc26 251 SUPERFAMILY SSF46785 20 83 1.23E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02410 2fed0f80d0db5367e493af7ead1ecc26 251 Gene3D G3DSA:1.20.120.530 76 225 6.1E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS02410 2fed0f80d0db5367e493af7ead1ecc26 251 SMART SM00345 21 79 7.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS02410 2fed0f80d0db5367e493af7ead1ecc26 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 77 9.3E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS02410 2fed0f80d0db5367e493af7ead1ecc26 251 SUPERFAMILY SSF48008 85 220 1.83E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS02410 2fed0f80d0db5367e493af7ead1ecc26 251 Gene3D G3DSA:1.10.10.10 6 75 2.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02410 2fed0f80d0db5367e493af7ead1ecc26 251 SMART SM00895 89 212 3.7E-19 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS27475 1ecb8a4853af15cca4b8ffad62ba67d1 313 Pfam PF00294 pfkB family carbohydrate kinase 13 301 6.5E-41 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CVS48_RS27475 1ecb8a4853af15cca4b8ffad62ba67d1 313 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 8 310 3.6E-124 T 29-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 CVS48_RS27475 1ecb8a4853af15cca4b8ffad62ba67d1 313 SUPERFAMILY SSF53613 13 308 5.46E-57 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS27475 1ecb8a4853af15cca4b8ffad62ba67d1 313 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 52 75 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CVS48_RS27475 1ecb8a4853af15cca4b8ffad62ba67d1 313 Gene3D G3DSA:3.40.1190.20 4 310 1.2E-57 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS26215 9fc8ef31101b00397b0129479fa210ea 508 Pfam PF01425 Amidase 33 488 1.0E-73 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS26215 9fc8ef31101b00397b0129479fa210ea 508 ProSitePatterns PS00571 Amidases signature. 168 199 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CVS48_RS26215 9fc8ef31101b00397b0129479fa210ea 508 SUPERFAMILY SSF75304 7 497 1.96E-101 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS26215 9fc8ef31101b00397b0129479fa210ea 508 Gene3D G3DSA:3.90.1300.10 6 507 8.1E-106 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 13 200 5.1E-25 T 29-03-2018 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 SUPERFAMILY SSF51905 8 210 6.48E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 8.5E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 165 189 8.5E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 134 8.5E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 Gene3D G3DSA:3.50.50.60 9 153 6.5E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 Gene3D G3DSA:3.50.50.60 154 284 1.0E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 SUPERFAMILY SSF51905 243 355 1.18E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 SUPERFAMILY SSF51905 138 181 1.18E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 294 3.0E-7 T 29-03-2018 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 3.0E-7 T 29-03-2018 CVS48_RS18605 6b981cdc2df2fad996bc2b9f0b55b742 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 3.0E-7 T 29-03-2018 CVS48_RS10000 ea1994022f6043cce6b7df1a75b5bf9f 218 SUPERFAMILY SSF52833 1 86 1.03E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS10000 ea1994022f6043cce6b7df1a75b5bf9f 218 Gene3D G3DSA:3.40.30.10 1 93 4.0E-15 T 29-03-2018 CVS48_RS10000 ea1994022f6043cce6b7df1a75b5bf9f 218 SUPERFAMILY SSF47616 74 215 2.9E-11 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS10000 ea1994022f6043cce6b7df1a75b5bf9f 218 Gene3D G3DSA:1.20.1050.10 94 218 2.2E-10 T 29-03-2018 CVS48_RS10000 ea1994022f6043cce6b7df1a75b5bf9f 218 Pfam PF13410 Glutathione S-transferase, C-terminal domain 127 200 4.2E-6 T 29-03-2018 CVS48_RS10000 ea1994022f6043cce6b7df1a75b5bf9f 218 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 78 1.2E-14 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 SUPERFAMILY SSF55874 295 475 3.54E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 Gene3D G3DSA:3.30.565.10 307 477 1.8E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 SMART SM00388 240 305 2.4E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 Pfam PF08521 Two-component sensor kinase N-terminal 22 164 1.9E-37 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 SMART SM00387 359 477 4.1E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 475 3.7E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 Pfam PF00512 His Kinase A (phospho-acceptor) domain 241 298 7.0E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 SUPERFAMILY SSF47384 223 298 1.84E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 Gene3D G3DSA:1.10.287.130 230 300 4.7E-10 T 29-03-2018 CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 474 6.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 6.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS28895 d1be219b968548bd0aecfc5cc751348e 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 6.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS10845 b798d6bc67835286ec3c5c4462f19bc3 207 SUPERFAMILY SSF46689 6 79 4.41E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS10845 b798d6bc67835286ec3c5c4462f19bc3 207 Gene3D G3DSA:1.10.10.60 9 60 5.8E-12 T 29-03-2018 CVS48_RS10845 b798d6bc67835286ec3c5c4462f19bc3 207 TIGRFAM TIGR03384 betaine_BetI: transcriptional repressor BetI 2 190 2.5E-72 T 29-03-2018 IPR017757 Transcriptional repressor BetI CVS48_RS10845 b798d6bc67835286ec3c5c4462f19bc3 207 Gene3D G3DSA:1.10.357.10 61 196 9.2E-15 T 29-03-2018 CVS48_RS10845 b798d6bc67835286ec3c5c4462f19bc3 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 3.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS10845 b798d6bc67835286ec3c5c4462f19bc3 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CVS48_RS10845 b798d6bc67835286ec3c5c4462f19bc3 207 Hamap MF_00768 HTH-type transcriptional regulator BetI [betI]. 1 200 97.528 T 29-03-2018 IPR017757 Transcriptional repressor BetI CVS48_RS10845 b798d6bc67835286ec3c5c4462f19bc3 207 SUPERFAMILY SSF48498 81 192 7.41E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS10845 b798d6bc67835286ec3c5c4462f19bc3 207 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 83 191 2.5E-34 T 29-03-2018 CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 Gene3D G3DSA:3.40.50.920 592 721 1.4E-22 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 Pfam PF00676 Dehydrogenase E1 component 124 344 3.3E-51 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 Gene3D G3DSA:3.40.50.970 397 591 2.4E-50 T 29-03-2018 CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 SUPERFAMILY SSF52922 585 720 3.27E-26 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 Pfam PF02780 Transketolase, C-terminal domain 591 712 2.7E-22 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 Pfam PF02779 Transketolase, pyrimidine binding domain 402 573 2.8E-36 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 SUPERFAMILY SSF52518 27 366 4.47E-73 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 Gene3D G3DSA:3.40.50.970 23 351 2.2E-68 T 29-03-2018 CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 SMART SM00861 399 575 4.2E-43 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS09285 81c84c7f98378b3c7ff9eceeb2b40d8e 727 SUPERFAMILY SSF52518 401 600 3.35E-52 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS04290 cbcac6f24ad15f13f90d591df279fff8 367 SUPERFAMILY SSF54001 151 278 3.5E-20 T 29-03-2018 CVS48_RS04290 cbcac6f24ad15f13f90d591df279fff8 367 SMART SM00460 205 279 7.0E-14 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS04290 cbcac6f24ad15f13f90d591df279fff8 367 Gene3D G3DSA:3.90.260.10 186 301 4.2E-4 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS04290 cbcac6f24ad15f13f90d591df279fff8 367 Pfam PF01841 Transglutaminase-like superfamily 158 277 1.9E-22 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 SUPERFAMILY SSF81660 399 583 1.83E-39 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 SUPERFAMILY SSF81665 55 173 8.37E-105 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 SUPERFAMILY SSF81665 724 932 8.37E-105 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 SUPERFAMILY SSF81665 305 398 8.37E-105 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 406 412 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 Pfam PF00690 Cation transporter/ATPase, N-terminus 56 121 1.9E-12 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 Pfam PF00689 Cation transporting ATPase, C-terminus 758 924 5.1E-16 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 PRINTS PR01836 Magnesium-transporting ATPase signature 783 796 7.7E-83 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 PRINTS PR01836 Magnesium-transporting ATPase signature 803 819 7.7E-83 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 PRINTS PR01836 Magnesium-transporting ATPase signature 888 909 7.7E-83 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 PRINTS PR01836 Magnesium-transporting ATPase signature 334 353 7.7E-83 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 PRINTS PR01836 Magnesium-transporting ATPase signature 438 451 7.7E-83 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 PRINTS PR01836 Magnesium-transporting ATPase signature 733 748 7.7E-83 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 PRINTS PR01836 Magnesium-transporting ATPase signature 751 762 7.7E-83 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 PRINTS PR01836 Magnesium-transporting ATPase signature 838 859 7.7E-83 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 PRINTS PR01836 Magnesium-transporting ATPase signature 317 333 7.7E-83 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 Pfam PF00702 haloacid dehalogenase-like hydrolase 400 689 1.5E-20 T 29-03-2018 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 Gene3D G3DSA:2.70.150.10 64 305 8.0E-45 T 29-03-2018 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 SUPERFAMILY SSF81653 203 303 4.97E-28 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 46 934 0.0 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 640 764 1.2E-29 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 302 440 4.9E-22 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 Gene3D G3DSA:3.40.1110.10 361 582 1.1E-38 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 Pfam PF00122 E1-E2 ATPase 203 384 6.7E-49 T 29-03-2018 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 Gene3D G3DSA:1.20.1110.10 617 931 3.4E-55 T 29-03-2018 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 SMART SM00831 53 126 9.9E-5 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CVS48_RS01375 7833fb9924582b302b36291d61dbb822 934 SUPERFAMILY SSF56784 566 719 7.47E-37 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 SUPERFAMILY SSF51735 2 239 5.07E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 237 1.5E-48 T 29-03-2018 CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 Gene3D G3DSA:3.40.50.720 2 240 4.7E-63 T 29-03-2018 CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 211 1.1E-4 T 29-03-2018 CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.8E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.8E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08910 dc567653b081891173b3a23f1da7fc0b 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.8E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23400 0147239205e60f6a04160117c17e4785 366 SUPERFAMILY SSF56645 1 120 1.21E-12 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS23400 0147239205e60f6a04160117c17e4785 366 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 1 109 4.4E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS23400 0147239205e60f6a04160117c17e4785 366 Gene3D G3DSA:1.20.140.10 216 340 7.2E-23 T 29-03-2018 CVS48_RS23400 0147239205e60f6a04160117c17e4785 366 SUPERFAMILY SSF47203 222 338 1.3E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS23400 0147239205e60f6a04160117c17e4785 366 Gene3D G3DSA:1.10.540.10 1 110 2.4E-12 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS23400 0147239205e60f6a04160117c17e4785 366 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 335 8.7E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS20910 845523f8bec4acf8ab8e2e4a9b74d588 327 PIRSF PIRSF034367 1 327 4.8E-196 T 29-03-2018 IPR015004 Protein of unknown function DUF1852 CVS48_RS20910 845523f8bec4acf8ab8e2e4a9b74d588 327 Pfam PF08908 Domain of unknown function (DUF1852) 1 323 3.1E-186 T 29-03-2018 IPR015004 Protein of unknown function DUF1852 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 Gene3D G3DSA:3.30.70.1450 139 226 1.9E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 Gene3D G3DSA:3.40.50.720 227 366 1.0E-26 T 29-03-2018 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 SUPERFAMILY SSF51735 1 151 1.69E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 4.7E-21 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.7E-21 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 4.7E-21 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 4.7E-21 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.7E-21 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 SUPERFAMILY SSF116726 136 222 1.19E-8 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 Gene3D G3DSA:3.30.70.1450 368 459 2.4E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 Pfam PF02254 TrkA-N domain 234 351 6.8E-25 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 Pfam PF02254 TrkA-N domain 3 124 5.1E-28 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 Pfam PF02080 TrkA-C domain 391 452 5.9E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 Pfam PF02080 TrkA-C domain 154 222 1.0E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 SUPERFAMILY SSF51735 232 377 6.86E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 SUPERFAMILY SSF116726 391 441 1.96E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS07955 1e6a9231c2f3f5a1bd83537f617b7cee 459 Gene3D G3DSA:3.40.50.720 2 138 2.9E-26 T 29-03-2018 CVS48_RS12240 7667d01e6c64de70a6da92aa4d5badc6 347 Pfam PF04773 FecR protein 133 228 1.4E-20 T 29-03-2018 IPR006860 FecR protein CVS48_RS12240 7667d01e6c64de70a6da92aa4d5badc6 347 PIRSF PIRSF018266 20 342 7.8E-93 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS12240 7667d01e6c64de70a6da92aa4d5badc6 347 Pfam PF16220 Domain of unknown function (DUF4880) 31 73 1.7E-12 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS26625 4b7db67cd8bea280c3d68131231c55f7 372 SUPERFAMILY SSF52283 1 167 1.02E-48 T 29-03-2018 CVS48_RS26625 4b7db67cd8bea280c3d68131231c55f7 372 Gene3D G3DSA:3.40.50.720 194 372 1.1E-45 T 29-03-2018 CVS48_RS26625 4b7db67cd8bea280c3d68131231c55f7 372 SMART SM01003 4 136 7.5E-65 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CVS48_RS26625 4b7db67cd8bea280c3d68131231c55f7 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 369 1.5E-71 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CVS48_RS26625 4b7db67cd8bea280c3d68131231c55f7 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 1.0E-39 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CVS48_RS26625 4b7db67cd8bea280c3d68131231c55f7 372 Gene3D G3DSA:3.40.50.720 1 193 6.4E-48 T 29-03-2018 CVS48_RS26625 4b7db67cd8bea280c3d68131231c55f7 372 SUPERFAMILY SSF51735 136 320 3.42E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS26625 4b7db67cd8bea280c3d68131231c55f7 372 SMART SM01002 145 314 4.0E-83 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CVS48_RS00750 eb37efa62db6b01cb60c9f531efb66e6 730 Gene3D G3DSA:3.40.50.300 129 662 1.6E-27 T 29-03-2018 CVS48_RS00750 eb37efa62db6b01cb60c9f531efb66e6 730 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 7 657 3.0E-266 T 29-03-2018 IPR022458 Conjugative coupling factor TraG/TraD CVS48_RS00750 eb37efa62db6b01cb60c9f531efb66e6 730 TIGRFAM TIGR03754 conj_TOL_TraD: conjugative coupling factor TraD, PFGI-1 class 7 657 0.0 T 29-03-2018 IPR022503 Conjugative coupling factor TraG/TraD, PFGI-1 CVS48_RS00750 eb37efa62db6b01cb60c9f531efb66e6 730 SUPERFAMILY SSF52540 399 659 2.1E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00750 eb37efa62db6b01cb60c9f531efb66e6 730 SUPERFAMILY SSF52540 146 344 2.1E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00750 eb37efa62db6b01cb60c9f531efb66e6 730 Pfam PF12696 TraM recognition site of TraD and TraG 509 636 3.5E-10 T 29-03-2018 IPR032689 TraD/TraG, TraM recognition site CVS48_RS09260 74ec8a3a7719865bda77f1eca0c00caa 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 2.7E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09260 74ec8a3a7719865bda77f1eca0c00caa 293 Gene3D G3DSA:3.40.190.10 179 263 3.4E-25 T 29-03-2018 CVS48_RS09260 74ec8a3a7719865bda77f1eca0c00caa 293 SUPERFAMILY SSF53850 91 292 5.61E-43 T 29-03-2018 CVS48_RS09260 74ec8a3a7719865bda77f1eca0c00caa 293 SUPERFAMILY SSF46785 2 112 5.82E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09260 74ec8a3a7719865bda77f1eca0c00caa 293 Pfam PF03466 LysR substrate binding domain 89 290 3.9E-44 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS09260 74ec8a3a7719865bda77f1eca0c00caa 293 Gene3D G3DSA:1.10.10.10 1 85 7.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09260 74ec8a3a7719865bda77f1eca0c00caa 293 Gene3D G3DSA:3.40.190.10 93 178 8.6E-18 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:3.40.50.300 1093 1102 0.18 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:3.40.50.300 659 1004 1.0E-48 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 SUPERFAMILY SSF52540 486 617 6.74E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 SUPERFAMILY SSF52540 6 208 6.74E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:3.40.50.300 1103 1139 0.4 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 SUPERFAMILY SSF52540 666 970 1.12E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 SMART SM00382 1086 1540 4.4 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 SMART SM00382 679 966 0.35 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 SMART SM00382 1608 1895 3.0 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 SUPERFAMILY SSF52540 1590 1902 6.5E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 SUPERFAMILY SSF52540 1069 1267 5.91E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 SUPERFAMILY SSF52540 1406 1545 5.91E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:1.20.1580.10 92 535 2.8E-86 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Pfam PF00005 ABC transporter 670 898 1.1E-6 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:3.40.50.300 1588 1623 0.015 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 ProSitePatterns PS00211 ABC transporters family signature. 1463 1477 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 984 2.6E-287 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:1.20.1580.10 1156 1463 1.1E-61 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:3.40.50.300 1017 1092 0.19 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:3.40.50.300 1624 1666 0.1 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 ProSitePatterns PS00211 ABC transporters family signature. 1806 1820 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:3.40.50.300 1795 1911 4.0E-22 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:3.40.50.300 8 49 0.0038 T 29-03-2018 CVS48_RS01655 12b8af177d60510e91f9ab56b2c8d1c3 1935 Gene3D G3DSA:1.20.1580.10 1669 1794 5.7E-37 T 29-03-2018 CVS48_RS27745 c1c4688c4f2462a713470247b0c62b03 310 SUPERFAMILY SSF54506 3 308 8.3E-94 T 29-03-2018 CVS48_RS27745 c1c4688c4f2462a713470247b0c62b03 310 Pfam PF05544 Proline racemase 6 308 1.4E-99 T 29-03-2018 IPR008794 Proline racemase family CVS48_RS27745 c1c4688c4f2462a713470247b0c62b03 310 Gene3D G3DSA:3.10.310.10 142 286 4.4E-50 T 29-03-2018 CVS48_RS27745 c1c4688c4f2462a713470247b0c62b03 310 Gene3D G3DSA:3.10.310.10 1 141 8.4E-30 T 29-03-2018 CVS48_RS27745 c1c4688c4f2462a713470247b0c62b03 310 PIRSF PIRSF029792 1 310 4.3E-92 T 29-03-2018 IPR008794 Proline racemase family CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 PRINTS PR00471 Acetate kinase family signature 14 25 1.9E-36 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 PRINTS PR00471 Acetate kinase family signature 185 198 1.9E-36 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 PRINTS PR00471 Acetate kinase family signature 214 235 1.9E-36 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 PRINTS PR00471 Acetate kinase family signature 381 393 1.9E-36 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 PRINTS PR00471 Acetate kinase family signature 307 320 1.9E-36 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 PRINTS PR00471 Acetate kinase family signature 329 345 1.9E-36 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 214 231 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 SUPERFAMILY SSF53067 170 400 6.74E-73 T 29-03-2018 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 Gene3D G3DSA:3.30.420.40 13 207 5.3E-61 T 29-03-2018 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 TIGRFAM TIGR00016 ackA: acetate kinase 11 399 5.6E-100 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 Gene3D G3DSA:3.30.420.40 208 403 1.2E-65 T 29-03-2018 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 Hamap MF_00020 Acetate kinase [ackA]. 1 403 146.546 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 Pfam PF00871 Acetokinase family 14 394 5.4E-100 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 SUPERFAMILY SSF53067 13 207 1.66E-57 T 29-03-2018 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 14 25 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS13160 96a4ad31cfdba7643617fc0fedbb32a9 403 PIRSF PIRSF000722 10 403 3.2E-131 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 Hamap MF_01201 Alanine racemase. 2 374 32.805 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 41 51 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 TIGRFAM TIGR00492 alr: alanine racemase 5 371 1.0E-100 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 Gene3D G3DSA:2.40.37.10 236 373 4.3E-57 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 Pfam PF00842 Alanine racemase, C-terminal domain 249 370 2.3E-42 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 Gene3D G3DSA:3.20.20.10 6 235 2.2E-40 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 SUPERFAMILY SSF51419 9 250 1.79E-54 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 SUPERFAMILY SSF50621 244 371 9.42E-46 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 PRINTS PR00992 Alanine racemase signature 282 297 2.4E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 PRINTS PR00992 Alanine racemase signature 356 369 2.4E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 PRINTS PR00992 Alanine racemase signature 130 142 2.4E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 PRINTS PR00992 Alanine racemase signature 303 320 2.4E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 PRINTS PR00992 Alanine racemase signature 36 52 2.4E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 PRINTS PR00992 Alanine racemase signature 167 178 2.4E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 PRINTS PR00992 Alanine racemase signature 265 280 2.4E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 PRINTS PR00992 Alanine racemase signature 208 235 2.4E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 PRINTS PR00992 Alanine racemase signature 70 88 2.4E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 SMART SM01005 249 374 3.0E-65 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22620 bb39714a3ded593ba77442aebf4b1034 375 Pfam PF01168 Alanine racemase, N-terminal domain 10 235 2.2E-60 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS11075 76ad6a73ba816e20f153e411ee19a09a 324 PIRSF PIRSF006470 2 323 2.6E-67 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS11075 76ad6a73ba816e20f153e411ee19a09a 324 Gene3D G3DSA:1.10.30.10 118 285 3.9E-4 T 29-03-2018 IPR009071 High mobility group box domain CVS48_RS11075 76ad6a73ba816e20f153e411ee19a09a 324 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 285 8.1E-60 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS11075 76ad6a73ba816e20f153e411ee19a09a 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 301 1.4E-66 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS26660 9b8934143ace26bd3eab9c99635279c0 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 9.0E-165 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CVS48_RS26660 9b8934143ace26bd3eab9c99635279c0 357 SUPERFAMILY SSF51569 7 348 1.15E-136 T 29-03-2018 CVS48_RS26660 9b8934143ace26bd3eab9c99635279c0 357 Gene3D G3DSA:3.20.20.70 8 354 1.7E-132 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS26660 9b8934143ace26bd3eab9c99635279c0 357 Pfam PF00793 DAHP synthetase I family 41 338 5.5E-103 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CVS48_RS26660 9b8934143ace26bd3eab9c99635279c0 357 PIRSF PIRSF001361 1 352 1.3E-160 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CVS48_RS05125 c9ce2941b83fda0ba4631680ce4f975e 273 Gene3D G3DSA:3.20.20.70 20 267 3.4E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS05125 c9ce2941b83fda0ba4631680ce4f975e 273 Pfam PF00977 Histidine biosynthesis protein 21 254 2.0E-89 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CVS48_RS05125 c9ce2941b83fda0ba4631680ce4f975e 273 SUPERFAMILY SSF51366 18 271 2.75E-83 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CVS48_RS05125 c9ce2941b83fda0ba4631680ce4f975e 273 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 17 271 48.556 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CVS48_RS05125 c9ce2941b83fda0ba4631680ce4f975e 273 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 18 271 5.8E-113 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CVS48_RS20130 a7e5ec93c0f4c79a2af2a38356c61106 138 Gene3D G3DSA:3.30.160.20 1 138 4.5E-39 T 29-03-2018 CVS48_RS20130 a7e5ec93c0f4c79a2af2a38356c61106 138 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CVS48_RS20130 a7e5ec93c0f4c79a2af2a38356c61106 138 Pfam PF00472 RF-1 domain 8 132 2.0E-24 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CVS48_RS20130 a7e5ec93c0f4c79a2af2a38356c61106 138 SUPERFAMILY SSF75620 7 117 3.37E-14 T 29-03-2018 CVS48_RS08310 9b335db3b63c053b0c3d5018de5bc194 367 SUPERFAMILY SSF53335 31 171 6.75E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS08310 9b335db3b63c053b0c3d5018de5bc194 367 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 107 119 1.5E-6 T 29-03-2018 CVS48_RS08310 9b335db3b63c053b0c3d5018de5bc194 367 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 133 157 1.5E-6 T 29-03-2018 CVS48_RS08310 9b335db3b63c053b0c3d5018de5bc194 367 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 43 57 1.5E-6 T 29-03-2018 CVS48_RS08310 9b335db3b63c053b0c3d5018de5bc194 367 Gene3D G3DSA:3.40.50.150 11 264 1.2E-16 T 29-03-2018 CVS48_RS13020 924d3de06ac7f7f21d3db54aa93a3057 482 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 70 461 1.0E-57 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS13020 924d3de06ac7f7f21d3db54aa93a3057 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 377 391 1.1E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS13020 924d3de06ac7f7f21d3db54aa93a3057 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 439 452 1.1E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS13020 924d3de06ac7f7f21d3db54aa93a3057 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 304 326 1.1E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS13020 924d3de06ac7f7f21d3db54aa93a3057 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 362 376 1.1E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS13020 924d3de06ac7f7f21d3db54aa93a3057 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 74 93 1.1E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS13020 924d3de06ac7f7f21d3db54aa93a3057 482 SUPERFAMILY SSF56601 32 481 1.92E-87 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS13020 924d3de06ac7f7f21d3db54aa93a3057 482 Gene3D G3DSA:3.40.710.10 31 482 4.5E-35 T 29-03-2018 CVS48_RS13020 924d3de06ac7f7f21d3db54aa93a3057 482 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 47 481 7.3E-79 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS22315 f771f4ed245c9add95ba893f5f9b7bbe 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 7.4E-27 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS22315 f771f4ed245c9add95ba893f5f9b7bbe 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 215 6.6E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22315 f771f4ed245c9add95ba893f5f9b7bbe 217 SUPERFAMILY SSF161098 14 200 2.22E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22315 f771f4ed245c9add95ba893f5f9b7bbe 217 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 10 215 6.7E-81 T 29-03-2018 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC CVS48_RS22315 f771f4ed245c9add95ba893f5f9b7bbe 217 Gene3D G3DSA:1.10.3720.10 3 217 9.2E-43 T 29-03-2018 CVS48_RS28535 1ed74c464eccd1d8075ca5f6cc9b1e92 132 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 6 131 6.7E-55 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS28535 1ed74c464eccd1d8075ca5f6cc9b1e92 132 Gene3D G3DSA:2.170.150.20 1 132 6.6E-60 T 29-03-2018 CVS48_RS28535 1ed74c464eccd1d8075ca5f6cc9b1e92 132 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 7 130 37.939 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS28535 1ed74c464eccd1d8075ca5f6cc9b1e92 132 SUPERFAMILY SSF51316 4 131 8.37E-60 T 29-03-2018 IPR011057 Mss4-like CVS48_RS28535 1ed74c464eccd1d8075ca5f6cc9b1e92 132 Pfam PF01641 SelR domain 10 129 1.9E-53 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS29020 5e85fdaa997220e13d94ee2a0689512c 166 SUPERFAMILY SSF88659 90 160 3.36E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS29020 5e85fdaa997220e13d94ee2a0689512c 166 Pfam PF08281 Sigma-70, region 4 107 159 4.3E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS29020 5e85fdaa997220e13d94ee2a0689512c 166 SUPERFAMILY SSF88946 4 73 1.02E-9 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS29020 5e85fdaa997220e13d94ee2a0689512c 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 159 3.9E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS29020 5e85fdaa997220e13d94ee2a0689512c 166 Gene3D G3DSA:1.10.1740.10 1 80 6.9E-11 T 29-03-2018 CVS48_RS29020 5e85fdaa997220e13d94ee2a0689512c 166 Gene3D G3DSA:1.10.10.10 92 164 5.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS29020 5e85fdaa997220e13d94ee2a0689512c 166 Pfam PF04542 Sigma-70 region 2 8 76 8.4E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS04270 9fffb43a0add63273d4caca76a95ed03 206 PIRSF PIRSF006386 6 205 1.1E-56 T 29-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 CVS48_RS04270 9fffb43a0add63273d4caca76a95ed03 206 Pfam PF01323 DSBA-like thioredoxin domain 12 196 1.2E-38 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CVS48_RS04270 9fffb43a0add63273d4caca76a95ed03 206 SUPERFAMILY SSF52833 11 202 6.31E-39 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS04270 9fffb43a0add63273d4caca76a95ed03 206 Gene3D G3DSA:3.40.30.10 6 203 3.6E-44 T 29-03-2018 CVS48_RS01155 67a612b1f5532a804d43f29847f01d56 632 Pfam PF02754 Cysteine-rich domain 524 609 3.7E-12 T 29-03-2018 IPR004017 Cysteine-rich domain CVS48_RS01155 67a612b1f5532a804d43f29847f01d56 632 SUPERFAMILY SSF46548 229 348 6.45E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CVS48_RS01155 67a612b1f5532a804d43f29847f01d56 632 Gene3D G3DSA:1.10.1060.10 214 356 1.3E-23 T 29-03-2018 CVS48_RS01155 67a612b1f5532a804d43f29847f01d56 632 Pfam PF13183 4Fe-4S dicluster domain 243 332 4.2E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS01155 67a612b1f5532a804d43f29847f01d56 632 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 246 257 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS01155 67a612b1f5532a804d43f29847f01d56 632 Pfam PF11982 Domain of unknown function (DUF3483) 6 219 2.8E-77 T 29-03-2018 IPR021872 Protein of unknown function DUF3483 CVS48_RS01155 67a612b1f5532a804d43f29847f01d56 632 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 320 331 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS16110 3c08636893e3ef060cdbbd4a764783e9 168 Gene3D G3DSA:1.10.10.10 87 166 1.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16110 3c08636893e3ef060cdbbd4a764783e9 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 162 4.9E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16110 3c08636893e3ef060cdbbd4a764783e9 168 Gene3D G3DSA:1.10.1740.10 11 86 6.6E-7 T 29-03-2018 CVS48_RS16110 3c08636893e3ef060cdbbd4a764783e9 168 SUPERFAMILY SSF88946 15 90 1.61E-8 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16110 3c08636893e3ef060cdbbd4a764783e9 168 Pfam PF04542 Sigma-70 region 2 12 75 2.9E-5 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16110 3c08636893e3ef060cdbbd4a764783e9 168 Pfam PF08281 Sigma-70, region 4 107 158 3.6E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16110 3c08636893e3ef060cdbbd4a764783e9 168 SUPERFAMILY SSF88659 101 162 5.01E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS08705 af73eda40b21952efb8162ece3f64d1e 340 SUPERFAMILY SSF53822 62 333 3.93E-51 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS08705 af73eda40b21952efb8162ece3f64d1e 340 Gene3D G3DSA:3.40.50.2300 174 339 5.0E-44 T 29-03-2018 CVS48_RS08705 af73eda40b21952efb8162ece3f64d1e 340 SMART SM00354 4 74 3.8E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS08705 af73eda40b21952efb8162ece3f64d1e 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 51 4.4E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS08705 af73eda40b21952efb8162ece3f64d1e 340 Pfam PF13377 Periplasmic binding protein-like domain 176 336 2.0E-32 T 29-03-2018 CVS48_RS08705 af73eda40b21952efb8162ece3f64d1e 340 Gene3D G3DSA:1.10.260.40 6 63 3.8E-18 T 29-03-2018 CVS48_RS08705 af73eda40b21952efb8162ece3f64d1e 340 SUPERFAMILY SSF47413 6 62 3.94E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS08705 af73eda40b21952efb8162ece3f64d1e 340 Gene3D G3DSA:3.40.50.2300 64 173 6.1E-22 T 29-03-2018 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 ProSitePatterns PS01047 Heavy-metal-associated domain. 32 61 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 PRINTS PR00946 Mercury scavenger protein signature 6 24 3.1E-40 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 PRINTS PR00946 Mercury scavenger protein signature 80 94 3.1E-40 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 PRINTS PR00946 Mercury scavenger protein signature 24 35 3.1E-40 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 PRINTS PR00946 Mercury scavenger protein signature 51 66 3.1E-40 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 PRINTS PR00946 Mercury scavenger protein signature 35 51 3.1E-40 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 PRINTS PR00946 Mercury scavenger protein signature 66 80 3.1E-40 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 SUPERFAMILY SSF55008 21 93 3.4E-21 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 TIGRFAM TIGR02052 MerP: mercuric transport protein periplasmic component 5 95 2.8E-45 T 29-03-2018 IPR011795 Mercuric transport protein periplasmic component GO:0015097|GO:0015694|GO:0042597|GO:0045340|GO:0046689 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 Gene3D G3DSA:3.30.70.100 24 95 4.2E-23 T 29-03-2018 CVS48_RS00855 cb5205d98947b298ee31e9331525692a 95 Pfam PF00403 Heavy-metal-associated domain 29 89 1.6E-15 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS13275 88cec19ef246b28da477c6d69cd1cd03 611 Pfam PF01019 Gamma-glutamyltranspeptidase 32 603 8.4E-119 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS13275 88cec19ef246b28da477c6d69cd1cd03 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 496 513 1.9E-19 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS13275 88cec19ef246b28da477c6d69cd1cd03 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 109 127 1.9E-19 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS13275 88cec19ef246b28da477c6d69cd1cd03 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 127 146 1.9E-19 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS13275 88cec19ef246b28da477c6d69cd1cd03 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 472 487 1.9E-19 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS13275 88cec19ef246b28da477c6d69cd1cd03 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 38 63 1.9E-19 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS13275 88cec19ef246b28da477c6d69cd1cd03 611 SUPERFAMILY SSF56235 5 357 4.85E-133 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS13275 88cec19ef246b28da477c6d69cd1cd03 611 SUPERFAMILY SSF56235 415 610 4.85E-133 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS26205 faa32220ccd350692fd506579d37afeb 226 Gene3D G3DSA:3.30.70.260 140 191 5.3E-21 T 29-03-2018 CVS48_RS26205 faa32220ccd350692fd506579d37afeb 226 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 222 32.59 T 29-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CVS48_RS26205 faa32220ccd350692fd506579d37afeb 226 SUPERFAMILY SSF75445 132 203 1.05E-20 T 29-03-2018 CVS48_RS26205 faa32220ccd350692fd506579d37afeb 226 Gene3D G3DSA:3.40.50.1360 1 139 4.4E-37 T 29-03-2018 CVS48_RS26205 faa32220ccd350692fd506579d37afeb 226 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 54 218 1.2E-56 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CVS48_RS26205 faa32220ccd350692fd506579d37afeb 226 SUPERFAMILY SSF100950 4 150 1.16E-40 T 29-03-2018 CVS48_RS26205 faa32220ccd350692fd506579d37afeb 226 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 8 219 7.1E-62 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CVS48_RS11020 66a05d1b568a0fa409671d79f4dc532f 278 SUPERFAMILY SSF56784 14 261 4.96E-28 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS11020 66a05d1b568a0fa409671d79f4dc532f 278 Pfam PF08282 haloacid dehalogenase-like hydrolase 18 84 7.3E-6 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS11020 66a05d1b568a0fa409671d79f4dc532f 278 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 18 227 2.1E-19 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CVS48_RS11020 66a05d1b568a0fa409671d79f4dc532f 278 Gene3D G3DSA:3.40.50.1000 13 263 1.2E-24 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 1.2E-8 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 SUPERFAMILY SSF51735 156 268 1.1E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 SUPERFAMILY SSF51735 297 362 1.1E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 Gene3D G3DSA:3.90.180.10 1 179 8.2E-50 T 29-03-2018 CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 142 8.5E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 SMART SM00829 8 391 0.001 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 Pfam PF00107 Zinc-binding dehydrogenase 189 258 1.8E-11 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 SUPERFAMILY SSF50129 1 195 3.5E-57 T 29-03-2018 IPR011032 GroES-like CVS48_RS25650 8dc935e780ef306ed9c5e928d937c560 402 Gene3D G3DSA:3.40.50.720 180 345 2.5E-23 T 29-03-2018 CVS48_RS06050 024d5575873379fbe4f38b14c3ad938b 90 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 74 2.7E-28 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CVS48_RS06050 024d5575873379fbe4f38b14c3ad938b 90 Pfam PF01809 Haemolytic domain 4 69 8.9E-31 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CVS48_RS06050 024d5575873379fbe4f38b14c3ad938b 90 SMART SM01234 2 69 2.2E-45 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CVS48_RS06050 024d5575873379fbe4f38b14c3ad938b 90 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 69 2.0E-23 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CVS48_RS06050 024d5575873379fbe4f38b14c3ad938b 90 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 70 24.466 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CVS48_RS12120 c9be12876cf2c64ea128a687b3e2a5aa 347 Gene3D G3DSA:3.40.800.20 1 347 6.4E-82 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS12120 c9be12876cf2c64ea128a687b3e2a5aa 347 SUPERFAMILY SSF52768 2 345 3.26E-87 T 29-03-2018 CVS48_RS12120 c9be12876cf2c64ea128a687b3e2a5aa 347 PRINTS PR01270 Histone deacetylase superfamily signature 161 184 2.6E-12 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS12120 c9be12876cf2c64ea128a687b3e2a5aa 347 PRINTS PR01270 Histone deacetylase superfamily signature 194 209 2.6E-12 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS12120 c9be12876cf2c64ea128a687b3e2a5aa 347 PRINTS PR01270 Histone deacetylase superfamily signature 280 290 2.6E-12 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS12120 c9be12876cf2c64ea128a687b3e2a5aa 347 Pfam PF00850 Histone deacetylase domain 28 343 1.2E-65 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS05145 4d40c5bc7bbe796d0e8c510c5d629ff0 75 Pfam PF02416 mttA/Hcf106 family 5 49 3.3E-13 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CVS48_RS05145 4d40c5bc7bbe796d0e8c510c5d629ff0 75 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 66 22.413 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CVS48_RS05145 4d40c5bc7bbe796d0e8c510c5d629ff0 75 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 46 3.6E-23 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CVS48_RS27920 564693097766d7ecd738828e4c988f27 329 SUPERFAMILY SSF56327 160 328 1.36E-60 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CVS48_RS27920 564693097766d7ecd738828e4c988f27 329 SUPERFAMILY SSF51735 5 158 1.79E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS27920 564693097766d7ecd738828e4c988f27 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 5 322 2.9E-144 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CVS48_RS27920 564693097766d7ecd738828e4c988f27 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 56.982 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CVS48_RS27920 564693097766d7ecd738828e4c988f27 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 155 7.1E-38 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CVS48_RS27920 564693097766d7ecd738828e4c988f27 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 324 2.8E-31 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CVS48_RS27920 564693097766d7ecd738828e4c988f27 329 Gene3D G3DSA:3.40.50.720 7 158 7.6E-28 T 29-03-2018 CVS48_RS27920 564693097766d7ecd738828e4c988f27 329 PIRSF PIRSF000102 2 328 1.6E-65 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CVS48_RS27920 564693097766d7ecd738828e4c988f27 329 Gene3D G3DSA:3.90.110.10 159 326 3.3E-49 T 29-03-2018 CVS48_RS06955 cf5d45aadf97cb8302fbdf4c5b098b30 403 SUPERFAMILY SSF56024 10 188 4.97E-39 T 29-03-2018 CVS48_RS06955 cf5d45aadf97cb8302fbdf4c5b098b30 403 Gene3D G3DSA:3.30.870.10 4 204 1.1E-30 T 29-03-2018 CVS48_RS06955 cf5d45aadf97cb8302fbdf4c5b098b30 403 Gene3D G3DSA:3.30.870.10 216 375 6.6E-29 T 29-03-2018 CVS48_RS06955 cf5d45aadf97cb8302fbdf4c5b098b30 403 SMART SM00155 116 143 1.1E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS06955 cf5d45aadf97cb8302fbdf4c5b098b30 403 SMART SM00155 306 332 0.0024 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS06955 cf5d45aadf97cb8302fbdf4c5b098b30 403 Hamap MF_01917 Cardiolipin synthase B [clsB]. 7 403 46.049 T 29-03-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 CVS48_RS06955 cf5d45aadf97cb8302fbdf4c5b098b30 403 Pfam PF13091 PLD-like domain 29 139 2.7E-14 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS06955 cf5d45aadf97cb8302fbdf4c5b098b30 403 Pfam PF13091 PLD-like domain 237 357 3.7E-23 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS06955 cf5d45aadf97cb8302fbdf4c5b098b30 403 SUPERFAMILY SSF56024 185 377 1.1E-37 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 9.9E-21 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 9.9E-21 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 9.9E-21 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 9.9E-21 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 Gene3D G3DSA:3.30.2090.10 185 270 5.1E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 SUPERFAMILY SSF82693 555 605 2.09E-6 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 Pfam PF00873 AcrB/AcrD/AcrF family 7 1009 4.2E-144 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 SUPERFAMILY SSF82693 43 138 1.03E-16 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 Gene3D G3DSA:1.20.1640.10 795 1013 7.1E-32 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 Gene3D G3DSA:3.30.70.1430 556 659 1.7E-13 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 SUPERFAMILY SSF82714 708 793 7.06E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 SUPERFAMILY SSF82866 793 1014 6.28E-41 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 SUPERFAMILY SSF82714 188 269 1.12E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 SUPERFAMILY SSF82693 140 185 1.1E-13 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 SUPERFAMILY SSF82693 271 326 1.1E-13 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 Gene3D G3DSA:3.30.70.1430 43 147 4.4E-26 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 SUPERFAMILY SSF82866 298 491 1.01E-35 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 Gene3D G3DSA:1.20.1640.10 297 499 3.7E-32 T 29-03-2018 CVS48_RS18500 dc9ea15de938fa31cbe2f9a97dfe782e 1034 Gene3D G3DSA:3.30.2090.10 707 794 7.4E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 Gene3D G3DSA:1.10.10.10 8 90 2.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 Gene3D G3DSA:3.40.640.10 151 400 8.0E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 Pfam PF00155 Aminotransferase class I and II 150 438 1.3E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 SUPERFAMILY SSF53383 116 497 4.03E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 88 6.5E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 Gene3D G3DSA:3.90.1150.10 401 499 1.6E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 4.3E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 4.3E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 SUPERFAMILY SSF46785 23 92 9.63E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15615 d109a8b2de14bf5fdbf8dfd2c3f41e77 500 SMART SM00345 30 88 1.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15685 664b270713366de1b1b89dcee0779228 177 SMART SM00987 20 175 3.9E-9 T 29-03-2018 CVS48_RS15685 664b270713366de1b1b89dcee0779228 177 SMART SM00986 20 175 3.9E-9 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS15685 664b270713366de1b1b89dcee0779228 177 Gene3D G3DSA:3.40.470.10 15 177 4.3E-46 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS15685 664b270713366de1b1b89dcee0779228 177 SUPERFAMILY SSF52141 19 175 1.44E-34 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS15685 664b270713366de1b1b89dcee0779228 177 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 18 171 1.1E-48 T 29-03-2018 IPR026353 Hypoxanthine-DNA glycosylase CVS48_RS15685 664b270713366de1b1b89dcee0779228 177 Pfam PF03167 Uracil DNA glycosylase superfamily 24 173 1.7E-8 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS23770 62f57acc02689aeb8bf14a181a1a7735 369 Gene3D G3DSA:3.40.50.720 2 204 5.7E-24 T 29-03-2018 CVS48_RS23770 62f57acc02689aeb8bf14a181a1a7735 369 Gene3D G3DSA:3.90.25.10 251 369 2.8E-34 T 29-03-2018 CVS48_RS23770 62f57acc02689aeb8bf14a181a1a7735 369 Gene3D G3DSA:3.90.25.10 205 250 1.7E-24 T 29-03-2018 CVS48_RS23770 62f57acc02689aeb8bf14a181a1a7735 369 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 350 1.0E-175 T 29-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 CVS48_RS23770 62f57acc02689aeb8bf14a181a1a7735 369 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 353 57.102 T 29-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 CVS48_RS23770 62f57acc02689aeb8bf14a181a1a7735 369 SUPERFAMILY SSF51735 3 349 5.71E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23770 62f57acc02689aeb8bf14a181a1a7735 369 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 343 5.6E-158 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 PIRSF PIRSF016578 223 364 1.0E-11 T 29-03-2018 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 PIRSF PIRSF016578 3 193 4.0E-11 T 29-03-2018 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 Gene3D G3DSA:2.40.110.10 119 215 1.0E-38 T 29-03-2018 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 3.6E-26 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 SUPERFAMILY SSF47203 225 374 4.83E-58 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 Gene3D G3DSA:1.10.540.10 1 118 4.5E-38 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 3.6E-51 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 7.9E-36 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 SUPERFAMILY SSF56645 2 240 1.05E-82 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 Gene3D G3DSA:1.20.140.10 216 375 6.3E-61 T 29-03-2018 CVS48_RS19990 7464f1279babd886818d5370fa44888a 375 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 377 2.7E-45 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 PIRSF PIRSF016578 211 382 2.2E-11 T 29-03-2018 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 PIRSF PIRSF016578 3 192 1.4E-6 T 29-03-2018 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 SUPERFAMILY SSF56645 2 240 1.24E-79 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 6.1E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 Gene3D G3DSA:1.20.140.10 217 383 2.0E-60 T 29-03-2018 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 Gene3D G3DSA:1.10.540.10 1 119 2.2E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 SUPERFAMILY SSF47203 225 378 8.22E-57 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 1.0E-26 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS17260 6a75ebba07dafea4675fdac120f33843 384 Gene3D G3DSA:2.40.110.10 120 216 2.9E-40 T 29-03-2018 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 SMART SM00357 52 118 5.7E-17 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 8.0E-31 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 241.599 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 6.4E-16 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 SUPERFAMILY SSF52540 90 371 9.09E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 SMART SM00959 5 47 4.3E-17 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 SMART SM00382 170 337 9.8E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 Gene3D G3DSA:3.40.50.300 129 419 1.7E-57 T 29-03-2018 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 Gene3D G3DSA:2.40.50.140 2 126 1.2E-44 T 29-03-2018 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 SUPERFAMILY SSF68912 1 46 8.24E-12 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 SUPERFAMILY SSF50249 49 125 6.28E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.9E-23 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS14460 3b94b94e501c58053105c916179ad106 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 418 9.4E-208 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CVS48_RS04175 b2dbeb1814c4b8f3725f5a9c32cda495 221 SUPERFAMILY SSF100950 2 220 6.35E-73 T 29-03-2018 CVS48_RS04175 b2dbeb1814c4b8f3725f5a9c32cda495 221 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 220 3.3E-99 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CVS48_RS04175 b2dbeb1814c4b8f3725f5a9c32cda495 221 SMART SM00882 6 219 1.8E-68 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS04175 b2dbeb1814c4b8f3725f5a9c32cda495 221 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS04175 b2dbeb1814c4b8f3725f5a9c32cda495 221 Pfam PF01144 Coenzyme A transferase 8 218 6.5E-61 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS04175 b2dbeb1814c4b8f3725f5a9c32cda495 221 Gene3D G3DSA:3.40.1080.10 2 221 5.3E-75 T 29-03-2018 CVS48_RS02500 d33866c69ac150b3bb04682eb982bdaa 104 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 1 84 2.7E-23 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CVS48_RS02500 d33866c69ac150b3bb04682eb982bdaa 104 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 84 14.804 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CVS48_RS02500 d33866c69ac150b3bb04682eb982bdaa 104 Pfam PF04999 Cell division protein FtsL 2 84 8.9E-18 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CVS48_RS03330 5e50fe74c77c20e84f418e4b867c3b05 195 SUPERFAMILY SSF143456 15 195 5.36E-59 T 29-03-2018 CVS48_RS03330 5e50fe74c77c20e84f418e4b867c3b05 195 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 14 195 37.079 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 CVS48_RS03330 5e50fe74c77c20e84f418e4b867c3b05 195 Pfam PF02622 Uncharacterized ACR, COG1678 25 182 5.4E-44 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 CVS48_RS03330 5e50fe74c77c20e84f418e4b867c3b05 195 Gene3D G3DSA:3.40.1740.10 120 186 1.2E-8 T 29-03-2018 CVS48_RS03330 5e50fe74c77c20e84f418e4b867c3b05 195 Gene3D G3DSA:3.40.1740.10 1 104 1.7E-28 T 29-03-2018 CVS48_RS00640 f5e111f6ab23e91d41fddab1f582e3be 316 Pfam PF06834 TraU protein 37 304 3.8E-72 T 29-03-2018 IPR009649 TraU CVS48_RS00640 f5e111f6ab23e91d41fddab1f582e3be 316 TIGRFAM TIGR03756 conj_TIGR03756: integrating conjugative element protein, PFL_4710 family 30 314 1.6E-133 T 29-03-2018 IPR026331 Integrating conjugative element protein PFL_4710 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.6E-40 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 Gene3D G3DSA:3.40.50.720 138 263 4.6E-41 T 29-03-2018 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 SUPERFAMILY SSF53223 1 121 1.34E-39 T 29-03-2018 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 Gene3D G3DSA:3.40.50.10860 11 137 1.6E-46 T 29-03-2018 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 38.868 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 SUPERFAMILY SSF51735 122 280 5.36E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 1.4E-70 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 2.4E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 2.4E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 2.4E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 2.4E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 2.4E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 2.4E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 2.4E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS16665 e9e1ad44f2929791de30434c765082cd 283 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CVS48_RS06350 d31b2d664a8c82a858b1f90e2f8adecd 307 SUPERFAMILY SSF46785 45 118 2.53E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06350 d31b2d664a8c82a858b1f90e2f8adecd 307 Gene3D G3DSA:3.30.450.40 116 294 1.3E-40 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS06350 d31b2d664a8c82a858b1f90e2f8adecd 307 SMART SM00346 45 135 1.4E-24 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS06350 d31b2d664a8c82a858b1f90e2f8adecd 307 Pfam PF09339 IclR helix-turn-helix domain 47 94 2.4E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS06350 d31b2d664a8c82a858b1f90e2f8adecd 307 SUPERFAMILY SSF55781 111 294 7.85E-38 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS06350 d31b2d664a8c82a858b1f90e2f8adecd 307 Pfam PF01614 Bacterial transcriptional regulator 166 289 7.2E-16 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS06350 d31b2d664a8c82a858b1f90e2f8adecd 307 Gene3D G3DSA:1.10.10.10 36 115 1.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19820 a9f37cea5b7169118b1bc4fd1e3be359 252 Pfam PF01975 Survival protein SurE 3 182 2.0E-58 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CVS48_RS19820 a9f37cea5b7169118b1bc4fd1e3be359 252 SUPERFAMILY SSF64167 1 247 1.31E-83 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CVS48_RS19820 a9f37cea5b7169118b1bc4fd1e3be359 252 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 250 38.431 T 29-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CVS48_RS19820 a9f37cea5b7169118b1bc4fd1e3be359 252 Gene3D G3DSA:3.40.1210.10 1 251 3.3E-84 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CVS48_RS19820 a9f37cea5b7169118b1bc4fd1e3be359 252 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 233 7.4E-63 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CVS48_RS01170 1b50606df2a423ef546f6eef25c3d10a 328 SUPERFAMILY SSF51556 6 321 2.62E-88 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS01170 1b50606df2a423ef546f6eef25c3d10a 328 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 6 318 1.4E-96 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CVS48_RS01170 1b50606df2a423ef546f6eef25c3d10a 328 Gene3D G3DSA:3.20.20.140 1 323 1.6E-91 T 29-03-2018 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 164 185 1.7E-65 T 29-03-2018 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 89 114 1.7E-65 T 29-03-2018 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 237 258 1.7E-65 T 29-03-2018 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 327 339 1.7E-65 T 29-03-2018 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 117 137 1.7E-65 T 29-03-2018 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 259 285 1.7E-65 T 29-03-2018 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 432 451 1.7E-65 T 29-03-2018 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 91 111 7.3E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 431 453 7.3E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 495 516 7.3E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 277 299 7.3E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 65 89 7.3E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 675 9.1E-241 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 Pfam PF00361 Proton-conducting membrane transporter 140 434 4.2E-86 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28650 5206f05f1f1beb039bd9478edc57fb06 680 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 128 2.0E-25 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 12 502 31.959 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 Pfam PF08245 Mur ligase middle domain 136 267 8.1E-26 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 14 499 4.1E-110 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 SUPERFAMILY SSF53623 128 272 2.35E-46 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 SUPERFAMILY SSF53623 304 361 2.35E-46 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 Gene3D G3DSA:3.40.1190.10 112 363 5.2E-57 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 Gene3D G3DSA:3.40.50.720 2 111 2.1E-14 T 29-03-2018 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 Pfam PF02875 Mur ligase family, glutamate ligase domain 365 434 2.0E-5 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 Gene3D G3DSA:3.90.190.20 369 501 1.2E-36 T 29-03-2018 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 SUPERFAMILY SSF51984 14 111 5.89E-12 T 29-03-2018 CVS48_RS02480 d0bba48d140834aad7668f121109c732 510 SUPERFAMILY SSF53244 363 502 2.61E-43 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS25560 e675a18c99ed30f1e11581736a207d41 111 SUPERFAMILY SSF50249 2 101 1.46E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS25560 e675a18c99ed30f1e11581736a207d41 111 Gene3D G3DSA:2.40.50.140 38 100 2.0E-14 T 29-03-2018 CVS48_RS25560 e675a18c99ed30f1e11581736a207d41 111 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 2 32 5.6E-8 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CVS48_RS25560 e675a18c99ed30f1e11581736a207d41 111 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 35 96 3.5E-18 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CVS48_RS14165 54570bddd95000249ec06d80fe5552b1 234 Gene3D G3DSA:1.20.120.530 76 218 3.6E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS14165 54570bddd95000249ec06d80fe5552b1 234 Pfam PF07729 FCD domain 84 205 1.6E-19 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS14165 54570bddd95000249ec06d80fe5552b1 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.6E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS14165 54570bddd95000249ec06d80fe5552b1 234 Gene3D G3DSA:1.10.10.10 2 75 3.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14165 54570bddd95000249ec06d80fe5552b1 234 SUPERFAMILY SSF46785 5 78 4.24E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14165 54570bddd95000249ec06d80fe5552b1 234 SMART SM00345 16 74 1.0E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS14165 54570bddd95000249ec06d80fe5552b1 234 SUPERFAMILY SSF48008 80 216 9.42E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS14165 54570bddd95000249ec06d80fe5552b1 234 SMART SM00895 84 209 7.7E-15 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS19735 d8ab8b2543410cd35978ad8a315a28dc 296 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 281 1.9E-73 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 CVS48_RS19735 d8ab8b2543410cd35978ad8a315a28dc 296 SUPERFAMILY SSF53335 9 282 5.54E-90 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS19735 d8ab8b2543410cd35978ad8a315a28dc 296 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 272 39.858 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 CVS48_RS19735 d8ab8b2543410cd35978ad8a315a28dc 296 Gene3D G3DSA:3.40.50.150 1 290 2.7E-84 T 29-03-2018 CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 SMART SM00382 225 405 9.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 330 343 3.2E-5 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 224 239 3.2E-5 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 302 316 3.2E-5 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 354 366 3.2E-5 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 414 506 2.9E-26 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 Gene3D G3DSA:3.30.230.10 2 184 1.0E-38 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 Gene3D G3DSA:3.40.50.300 204 402 5.8E-21 T 29-03-2018 CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 SUPERFAMILY SSF54211 10 185 5.31E-25 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 Pfam PF01078 Magnesium chelatase, subunit ChlI 206 406 6.6E-91 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 506 1.6E-154 T 29-03-2018 IPR004482 Mg chelatase-related protein CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 156 2.3E-34 T 29-03-2018 CVS48_RS15165 5e2df77707e51a8101c7b15bc9d90630 510 SUPERFAMILY SSF52540 206 508 2.58E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10935 718cf6ec1b5d1dc704db0fb9bfe1c90f 148 SMART SM00347 24 124 3.5E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS10935 718cf6ec1b5d1dc704db0fb9bfe1c90f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 2.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS10935 718cf6ec1b5d1dc704db0fb9bfe1c90f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 2.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS10935 718cf6ec1b5d1dc704db0fb9bfe1c90f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 2.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS10935 718cf6ec1b5d1dc704db0fb9bfe1c90f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 2.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS10935 718cf6ec1b5d1dc704db0fb9bfe1c90f 148 Gene3D G3DSA:1.10.10.10 2 142 1.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10935 718cf6ec1b5d1dc704db0fb9bfe1c90f 148 SUPERFAMILY SSF46785 9 139 3.76E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10935 718cf6ec1b5d1dc704db0fb9bfe1c90f 148 Pfam PF01047 MarR family 34 87 7.0E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS03040 21d047203904d839aed8ba79fe6dd8b4 384 SUPERFAMILY SSF53822 26 360 7.33E-83 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS03040 21d047203904d839aed8ba79fe6dd8b4 384 Pfam PF13458 Periplasmic binding protein 26 361 2.3E-60 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS03040 21d047203904d839aed8ba79fe6dd8b4 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 89 99 1.9E-12 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS03040 21d047203904d839aed8ba79fe6dd8b4 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 1.9E-12 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS03040 21d047203904d839aed8ba79fe6dd8b4 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 280 293 1.9E-12 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS03040 21d047203904d839aed8ba79fe6dd8b4 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 1.9E-12 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS03040 21d047203904d839aed8ba79fe6dd8b4 384 Gene3D G3DSA:3.40.50.2300 150 325 1.0E-36 T 29-03-2018 CVS48_RS03040 21d047203904d839aed8ba79fe6dd8b4 384 Gene3D G3DSA:3.40.50.2300 9 149 2.3E-20 T 29-03-2018 CVS48_RS00675 f0d0f5fe054878cbdcfa2af7c70a6b55 303 TIGRFAM TIGR03749 conj_TIGR03749: integrating conjugative element protein, PFL_4704 family 13 274 1.2E-112 T 29-03-2018 IPR021844 Integrating conjugative element protein, PFL4704 CVS48_RS00675 f0d0f5fe054878cbdcfa2af7c70a6b55 303 Pfam PF11920 Protein of unknown function (DUF3438) 9 283 4.9E-126 T 29-03-2018 IPR021844 Integrating conjugative element protein, PFL4704 CVS48_RS14380 860e2a9e48af3721b89e12a86e01b191 481 Gene3D G3DSA:1.20.1600.10 16 464 4.9E-85 T 29-03-2018 CVS48_RS14380 860e2a9e48af3721b89e12a86e01b191 481 Pfam PF02321 Outer membrane efflux protein 57 248 9.0E-25 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS14380 860e2a9e48af3721b89e12a86e01b191 481 Pfam PF02321 Outer membrane efflux protein 280 451 4.2E-21 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS14380 860e2a9e48af3721b89e12a86e01b191 481 SUPERFAMILY SSF56954 1 461 1.96E-92 T 29-03-2018 CVS48_RS14380 860e2a9e48af3721b89e12a86e01b191 481 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 8 458 9.6E-118 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS10535 acdf2940ecc6038a283fa9aca7138f19 187 Pfam PF00692 dUTPase 81 183 3.4E-7 T 29-03-2018 IPR029054 dUTPase-like CVS48_RS10535 acdf2940ecc6038a283fa9aca7138f19 187 Hamap MF_00146 dCTP deaminase [dcd]. 2 187 28.01 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CVS48_RS10535 acdf2940ecc6038a283fa9aca7138f19 187 Gene3D G3DSA:2.70.40.10 1 160 3.7E-57 T 29-03-2018 CVS48_RS10535 acdf2940ecc6038a283fa9aca7138f19 187 SUPERFAMILY SSF51283 3 186 1.3E-52 T 29-03-2018 IPR029054 dUTPase-like CVS48_RS10535 acdf2940ecc6038a283fa9aca7138f19 187 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 16 186 3.4E-47 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CVS48_RS17190 7d687d95a8ade24ab63cc0ff9e2fb944 188 SUPERFAMILY SSF53098 2 183 7.59E-62 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS17190 7d687d95a8ade24ab63cc0ff9e2fb944 188 Gene3D G3DSA:3.30.420.10 1 185 1.2E-61 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS17190 7d687d95a8ade24ab63cc0ff9e2fb944 188 Pfam PF01351 Ribonuclease HII 4 179 3.8E-32 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain CVS48_RS17190 7d687d95a8ade24ab63cc0ff9e2fb944 188 Hamap MF_00052_B Ribonuclease HII [rnhB]. 2 181 34.075 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 CVS48_RS26870 65953718165fed01e4c1c4b01ff4c46c 299 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 36.966 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 CVS48_RS26870 65953718165fed01e4c1c4b01ff4c46c 299 Pfam PF04381 Putative exonuclease, RdgC 1 296 3.7E-118 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 CVS48_RS22550 a0749878b5ca25a7fb86ec971cf52da9 323 PIRSF PIRSF017082 1 322 6.6E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22550 a0749878b5ca25a7fb86ec971cf52da9 323 Gene3D G3DSA:3.40.190.10 151 296 7.0E-13 T 29-03-2018 CVS48_RS22550 a0749878b5ca25a7fb86ec971cf52da9 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 3.3E-90 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22550 a0749878b5ca25a7fb86ec971cf52da9 323 SUPERFAMILY SSF53850 112 285 4.75E-14 T 29-03-2018 CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 SUPERFAMILY SSF52518 65 480 8.63E-125 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 TIGRFAM TIGR03186 AKGDH_not_PDH: alpha-ketoglutarate dehydrogenase 15 893 0.0 T 29-03-2018 IPR017600 Alpha-ketoglutarate dehydrogenase CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 144 313 6.8E-8 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 15 875 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 Gene3D G3DSA:3.40.50.970 483 717 8.2E-63 T 29-03-2018 CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 PIRSF PIRSF000156 8 894 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 SUPERFAMILY SSF52518 485 712 3.03E-93 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 Gene3D G3DSA:3.40.50.970 64 482 2.4E-82 T 29-03-2018 CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 Gene3D G3DSA:3.40.50.920 720 893 3.5E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS27860 f3a0931ea26df0ddd592e0792f92596f 895 SUPERFAMILY SSF52922 716 876 9.85E-45 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 Pfam PF00702 haloacid dehalogenase-like hydrolase 337 556 1.4E-36 T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 SUPERFAMILY SSF56784 399 643 2.63E-48 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 SUPERFAMILY SSF56784 339 358 2.63E-48 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 491 501 7.8E-26 T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 340 354 7.8E-26 T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 567 579 7.8E-26 T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 174 188 7.8E-26 T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 468 479 7.8E-26 T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 543 562 7.8E-26 T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 234 622 2.1E-57 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 Gene3D G3DSA:3.40.1110.10 355 507 2.3E-33 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 ProSitePatterns PS01229 Hypothetical cof family signature 2. 543 565 - T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 SUPERFAMILY SSF81653 127 240 3.27E-25 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 Gene3D G3DSA:1.20.1110.10 508 642 1.9E-21 T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 Gene3D G3DSA:1.20.1110.10 77 354 5.8E-33 T 29-03-2018 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 342 348 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 74 645 1.4E-170 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 SUPERFAMILY SSF81665 593 622 7.85E-19 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 SUPERFAMILY SSF81665 241 334 7.85E-19 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 SUPERFAMILY SSF81665 77 128 7.85E-19 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS08220 c6da17dfc03c98534721103dbee6ad6b 654 Pfam PF00122 E1-E2 ATPase 125 319 2.2E-48 T 29-03-2018 CVS48_RS12285 b81e0685cdf5b3ce5134955dc332d4ee 178 Pfam PF02308 MgtC family 32 156 3.2E-39 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CVS48_RS12285 b81e0685cdf5b3ce5134955dc332d4ee 178 PRINTS PR01837 MgtC/SapB protein signature 35 54 1.5E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CVS48_RS12285 b81e0685cdf5b3ce5134955dc332d4ee 178 PRINTS PR01837 MgtC/SapB protein signature 54 72 1.5E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CVS48_RS12285 b81e0685cdf5b3ce5134955dc332d4ee 178 PRINTS PR01837 MgtC/SapB protein signature 81 103 1.5E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CVS48_RS12285 b81e0685cdf5b3ce5134955dc332d4ee 178 PRINTS PR01837 MgtC/SapB protein signature 110 134 1.5E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CVS48_RS14110 d90debee0f41506ec49511c491d20980 220 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 217 38.136 T 29-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 CVS48_RS14110 d90debee0f41506ec49511c491d20980 220 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 215 1.9E-74 T 29-03-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 CVS48_RS14110 d90debee0f41506ec49511c491d20980 220 Gene3D G3DSA:3.40.50.150 16 217 1.3E-21 T 29-03-2018 CVS48_RS14110 d90debee0f41506ec49511c491d20980 220 PIRSF PIRSF023956 1 219 1.4E-74 T 29-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 CVS48_RS14110 d90debee0f41506ec49511c491d20980 220 SUPERFAMILY SSF53335 1 215 4.0E-55 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS14110 d90debee0f41506ec49511c491d20980 220 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 215 4.2E-81 T 29-03-2018 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 CVS48_RS28395 a045f3b877a9e5442a322d77be255b2c 287 Pfam PF00290 Tryptophan synthase alpha chain 18 261 5.0E-85 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS28395 a045f3b877a9e5442a322d77be255b2c 287 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 53 66 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS28395 a045f3b877a9e5442a322d77be255b2c 287 SUPERFAMILY SSF51366 6 253 5.27E-84 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CVS48_RS28395 a045f3b877a9e5442a322d77be255b2c 287 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 20 254 4.7E-72 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS28395 a045f3b877a9e5442a322d77be255b2c 287 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 276 33.475 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS28395 a045f3b877a9e5442a322d77be255b2c 287 Gene3D G3DSA:3.20.20.70 6 281 2.9E-74 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS12775 6ad1a627327cc4e14421a8b25efe3d86 267 SUPERFAMILY SSF53681 110 257 3.6E-32 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS12775 6ad1a627327cc4e14421a8b25efe3d86 267 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 215 1.4E-29 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS12775 6ad1a627327cc4e14421a8b25efe3d86 267 Hamap MF_00258 Glutamate racemase [murI]. 5 256 32.755 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS12775 6ad1a627327cc4e14421a8b25efe3d86 267 Gene3D G3DSA:3.40.50.1860 117 262 1.8E-40 T 29-03-2018 CVS48_RS12775 6ad1a627327cc4e14421a8b25efe3d86 267 SUPERFAMILY SSF53681 7 108 6.21E-30 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS12775 6ad1a627327cc4e14421a8b25efe3d86 267 Gene3D G3DSA:3.40.50.1860 3 116 1.2E-24 T 29-03-2018 CVS48_RS12775 6ad1a627327cc4e14421a8b25efe3d86 267 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS12775 6ad1a627327cc4e14421a8b25efe3d86 267 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS12775 6ad1a627327cc4e14421a8b25efe3d86 267 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 242 1.0E-57 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS23715 5f41c8be3047028846fd85c3e2d551ed 272 Gene3D G3DSA:3.40.50.1220 1 272 2.3E-63 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS23715 5f41c8be3047028846fd85c3e2d551ed 272 Pfam PF02146 Sir2 family 26 228 8.2E-47 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 CVS48_RS23715 5f41c8be3047028846fd85c3e2d551ed 272 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 2 272 60.901 T 29-03-2018 IPR026587 Sirtuin, class II Reactome: R-HSA-2151201 CVS48_RS23715 5f41c8be3047028846fd85c3e2d551ed 272 SUPERFAMILY SSF52467 6 272 1.47E-79 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS20275 8ef904bf6d2079b36576acf235f597b7 142 SUPERFAMILY SSF54593 1 136 1.29E-32 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS20275 8ef904bf6d2079b36576acf235f597b7 142 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 135 3.4E-7 T 29-03-2018 IPR028973 PhnB-like CVS48_RS20275 8ef904bf6d2079b36576acf235f597b7 142 Gene3D G3DSA:3.10.180.10 1 139 3.4E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS03695 621c97391e06fa0d5e2ffe1648a0d175 269 Gene3D G3DSA:3.20.20.70 4 263 1.8E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS03695 621c97391e06fa0d5e2ffe1648a0d175 269 SUPERFAMILY SSF110399 5 247 2.35E-90 T 29-03-2018 CVS48_RS03695 621c97391e06fa0d5e2ffe1648a0d175 269 Hamap MF_00443 Thiazole synthase [thiG]. 6 262 42.2 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CVS48_RS03695 621c97391e06fa0d5e2ffe1648a0d175 269 Pfam PF05690 Thiazole biosynthesis protein ThiG 9 255 5.9E-107 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CVS48_RS17035 4473cb3000489979a4c8a0d968e87636 461 Pfam PF07196 Flagellin hook IN motif 128 181 6.2E-10 T 29-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 CVS48_RS17035 4473cb3000489979a4c8a0d968e87636 461 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 223 445 1.2E-50 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CVS48_RS17035 4473cb3000489979a4c8a0d968e87636 461 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 108 4.8E-17 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CVS48_RS15835 5a46904c7a5669deefaceff315523545 303 Pfam PF03466 LysR substrate binding domain 87 292 4.3E-42 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS15835 5a46904c7a5669deefaceff315523545 303 Gene3D G3DSA:3.40.190.10 91 175 1.2E-17 T 29-03-2018 CVS48_RS15835 5a46904c7a5669deefaceff315523545 303 SUPERFAMILY SSF46785 4 109 9.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15835 5a46904c7a5669deefaceff315523545 303 SUPERFAMILY SSF53850 88 294 8.87E-43 T 29-03-2018 CVS48_RS15835 5a46904c7a5669deefaceff315523545 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15835 5a46904c7a5669deefaceff315523545 303 Gene3D G3DSA:3.40.190.10 176 261 6.7E-23 T 29-03-2018 CVS48_RS15835 5a46904c7a5669deefaceff315523545 303 Gene3D G3DSA:1.10.10.10 3 90 2.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 SUPERFAMILY SSF50692 888 1039 5.2E-26 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 Gene3D G3DSA:3.40.50.740 154 433 6.7E-18 T 29-03-2018 CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 SMART SM00926 67 149 7.8E-11 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 SUPERFAMILY SSF53706 133 909 6.16E-104 T 29-03-2018 CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 SUPERFAMILY SSF53706 66 106 6.16E-104 T 29-03-2018 CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 Gene3D G3DSA:2.40.40.20 866 1040 9.8E-29 T 29-03-2018 CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 Gene3D G3DSA:3.40.50.740 472 811 1.3E-28 T 29-03-2018 CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 Pfam PF00384 Molybdopterin oxidoreductase 232 695 4.4E-9 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 Pfam PF01568 Molydopterin dinucleotide binding domain 910 996 5.9E-12 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CVS48_RS15700 9b0c109aa34fea3ad2f6cb47aeb4749c 1040 Gene3D G3DSA:2.20.25.90 62 150 5.1E-12 T 29-03-2018 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 Gene3D G3DSA:1.10.287.130 261 332 3.7E-14 T 29-03-2018 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 SMART SM00388 271 336 6.3E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 384 494 6.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 Gene3D G3DSA:3.30.565.10 339 506 5.1E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 Pfam PF08521 Two-component sensor kinase N-terminal 50 194 2.1E-36 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 Pfam PF00512 His Kinase A (phospho-acceptor) domain 271 335 6.8E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 Gene3D G3DSA:1.20.5.1040 36 88 4.5E-4 T 29-03-2018 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 Gene3D G3DSA:1.20.5.1040 173 218 4.2E-7 T 29-03-2018 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 SUPERFAMILY SSF47384 254 335 2.75E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 SUPERFAMILY SSF55874 325 495 2.62E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 468 5.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 432 5.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 446 5.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS26855 c2fd670d22ebc48ea5a6de957fb6fc5f 516 SMART SM00387 381 495 1.3E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS19960 a7db03ed55950055cdd45f43708ec95d 433 Gene3D G3DSA:3.30.9.10 215 359 3.9E-26 T 29-03-2018 CVS48_RS19960 a7db03ed55950055cdd45f43708ec95d 433 SUPERFAMILY SSF54373 270 360 1.7E-17 T 29-03-2018 CVS48_RS19960 a7db03ed55950055cdd45f43708ec95d 433 Gene3D G3DSA:3.30.9.10 146 214 1.9E-12 T 29-03-2018 CVS48_RS19960 a7db03ed55950055cdd45f43708ec95d 433 SUPERFAMILY SSF51905 360 421 2.2E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19960 a7db03ed55950055cdd45f43708ec95d 433 SUPERFAMILY SSF51905 1 54 2.2E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19960 a7db03ed55950055cdd45f43708ec95d 433 SUPERFAMILY SSF51905 107 270 2.2E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19960 a7db03ed55950055cdd45f43708ec95d 433 Gene3D G3DSA:3.40.50.720 1 145 1.4E-9 T 29-03-2018 CVS48_RS19960 a7db03ed55950055cdd45f43708ec95d 433 Pfam PF01266 FAD dependent oxidoreductase 2 397 1.2E-75 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS19960 a7db03ed55950055cdd45f43708ec95d 433 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 50.005 T 29-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 CVS48_RS05620 f4ec60934e3b4d3f34c87c346303d1ea 137 Pfam PF04266 ASCH domain 28 133 9.7E-21 T 29-03-2018 IPR007374 ASCH domain CVS48_RS05620 f4ec60934e3b4d3f34c87c346303d1ea 137 Gene3D G3DSA:3.10.400.10 3 135 1.8E-45 T 29-03-2018 CVS48_RS05620 f4ec60934e3b4d3f34c87c346303d1ea 137 PIRSF PIRSF021320 5 136 2.5E-38 T 29-03-2018 IPR009326 Protein of unknown function DUF984 CVS48_RS05620 f4ec60934e3b4d3f34c87c346303d1ea 137 SMART SM01022 18 133 3.8E-36 T 29-03-2018 IPR007374 ASCH domain CVS48_RS05620 f4ec60934e3b4d3f34c87c346303d1ea 137 SUPERFAMILY SSF88697 12 133 2.31E-39 T 29-03-2018 IPR015947 PUA-like domain CVS48_RS25515 a43ee357393797c1eac9dbbca9479914 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 315 5.2E-83 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25515 a43ee357393797c1eac9dbbca9479914 320 SUPERFAMILY SSF53850 111 281 9.96E-11 T 29-03-2018 CVS48_RS25515 a43ee357393797c1eac9dbbca9479914 320 PIRSF PIRSF017082 1 319 3.1E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25515 a43ee357393797c1eac9dbbca9479914 320 Gene3D G3DSA:3.40.190.10 147 294 9.7E-10 T 29-03-2018 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 SUPERFAMILY SSF55826 218 392 1.06E-33 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 568 9.6E-223 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 Gene3D G3DSA:3.90.960.10 256 389 1.5E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.6E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.6E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.6E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.6E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 SUPERFAMILY SSF52954 467 574 1.96E-30 T 29-03-2018 IPR004154 Anticodon-binding CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 Pfam PF03129 Anticodon binding domain 478 570 1.7E-17 T 29-03-2018 IPR004154 Anticodon-binding CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 Gene3D G3DSA:3.30.930.10 390 461 1.5E-7 T 29-03-2018 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 Gene3D G3DSA:3.30.930.10 23 255 5.8E-66 T 29-03-2018 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 SUPERFAMILY SSF55681 10 237 5.53E-101 T 29-03-2018 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 SUPERFAMILY SSF55681 410 481 5.53E-101 T 29-03-2018 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 Gene3D G3DSA:3.40.50.800 462 576 3.5E-31 T 29-03-2018 IPR004154 Anticodon-binding CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 PIRSF PIRSF001535 1 576 1.4E-265 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 Pfam PF04073 Aminoacyl-tRNA editing domain 257 381 2.0E-29 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 462 3.9E-45 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS02670 9c03355cbb086590f3a94497f602621f 576 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 574 40.61 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 62 151 4.8E-24 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 SUPERFAMILY SSF55257 176 229 1.08E-31 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 SUPERFAMILY SSF55257 5 51 1.08E-31 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 SUPERFAMILY SSF56553 51 175 2.35E-42 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 SMART SM00662 21 231 2.9E-99 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 255 325 1.0E-34 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 SUPERFAMILY SSF47789 250 322 1.07E-26 T 29-03-2018 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 27 224 7.3E-23 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 22 315 7.4E-106 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 316 35.569 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 250 307 9.8E-25 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Gene3D G3DSA:1.10.150.20 245 327 8.5E-28 T 29-03-2018 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Gene3D G3DSA:3.30.1360.10 2 87 8.7E-18 T 29-03-2018 CVS48_RS06570 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Gene3D G3DSA:3.30.1360.10 109 228 7.6E-32 T 29-03-2018 CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 Gene3D G3DSA:3.40.50.720 7 53 5.2E-10 T 29-03-2018 CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 Gene3D G3DSA:3.40.50.720 54 257 1.3E-55 T 29-03-2018 CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 SUPERFAMILY SSF51735 11 251 2.07E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 249 4.5E-56 T 29-03-2018 CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.7E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.7E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.7E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.7E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.7E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS03365 6a2ebc6f67502de3d5b1056577da6827 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23405 e4c12a6f0485965b1357a385475425bc 399 SUPERFAMILY SSF47203 239 396 2.86E-21 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS23405 e4c12a6f0485965b1357a385475425bc 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 127 2.7E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS23405 e4c12a6f0485965b1357a385475425bc 399 SUPERFAMILY SSF56645 14 247 1.96E-70 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS23405 e4c12a6f0485965b1357a385475425bc 399 Gene3D G3DSA:1.20.140.10 228 399 1.9E-37 T 29-03-2018 CVS48_RS23405 e4c12a6f0485965b1357a385475425bc 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 227 1.8E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS23405 e4c12a6f0485965b1357a385475425bc 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 394 6.6E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS23405 e4c12a6f0485965b1357a385475425bc 399 Gene3D G3DSA:2.40.110.10 129 227 7.3E-35 T 29-03-2018 CVS48_RS23405 e4c12a6f0485965b1357a385475425bc 399 Gene3D G3DSA:1.10.540.10 3 128 3.5E-29 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS21790 984189fece3cd1e6f9daa04995cfc5e1 234 SMART SM00382 42 230 2.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21790 984189fece3cd1e6f9daa04995cfc5e1 234 Pfam PF00005 ABC transporter 33 181 1.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS21790 984189fece3cd1e6f9daa04995cfc5e1 234 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS21790 984189fece3cd1e6f9daa04995cfc5e1 234 SUPERFAMILY SSF52540 14 232 3.8E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21790 984189fece3cd1e6f9daa04995cfc5e1 234 Gene3D G3DSA:3.40.50.300 9 234 1.1E-60 T 29-03-2018 CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 SUPERFAMILY SSF53850 91 300 9.51E-40 T 29-03-2018 CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 Gene3D G3DSA:3.40.190.10 90 180 4.2E-21 T 29-03-2018 CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 SUPERFAMILY SSF46785 12 113 3.16E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 Gene3D G3DSA:1.10.10.10 1 83 1.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 Gene3D G3DSA:3.40.190.10 181 268 1.5E-18 T 29-03-2018 CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 Pfam PF03466 LysR substrate binding domain 89 292 6.9E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17920 95a5ebdcf1a2cafda5442b1c5ee4d59f 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 4.2E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 Gene3D G3DSA:3.30.1490.20 124 209 2.8E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 630 647 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 SUPERFAMILY SSF56059 83 347 3.18E-70 T 29-03-2018 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 SUPERFAMILY SSF52440 1 113 1.01E-44 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 SUPERFAMILY SSF51246 331 451 2.88E-39 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 4.3E-41 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 SMART SM01209 114 293 8.7E-4 T 29-03-2018 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 Pfam PF02785 Biotin carboxylase C-terminal domain 336 448 8.0E-36 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 Gene3D G3DSA:3.40.50.20 1 123 2.3E-50 T 29-03-2018 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 Gene3D G3DSA:3.30.470.20 210 450 1.8E-108 T 29-03-2018 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 SUPERFAMILY SSF51230 600 673 9.16E-22 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 Pfam PF00364 Biotin-requiring enzyme 608 673 5.9E-19 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 SMART SM00878 336 447 9.5E-56 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 4.7E-79 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 Gene3D G3DSA:2.40.50.100 606 674 2.9E-20 T 29-03-2018 CVS48_RS05525 844ca2f8cb4be57d6679c28650872fa2 675 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 PRINTS PR00147 DNA photolyase signature 326 342 1.8E-24 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 PRINTS PR00147 DNA photolyase signature 385 399 1.8E-24 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 PRINTS PR00147 DNA photolyase signature 346 364 1.8E-24 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 PRINTS PR00147 DNA photolyase signature 142 158 1.8E-24 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 Pfam PF03441 FAD binding domain of DNA photolyase 276 466 1.5E-77 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 Pfam PF00875 DNA photolyase 4 170 1.4E-43 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 SUPERFAMILY SSF52425 2 195 9.94E-50 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 326 338 - T 29-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 Gene3D G3DSA:1.25.40.80 131 293 5.1E-37 T 29-03-2018 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 Gene3D G3DSA:3.40.50.620 1 130 1.6E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 Gene3D G3DSA:1.10.579.10 294 470 6.1E-67 T 29-03-2018 CVS48_RS17395 bb709b8420df5a7d3f6517634fce1a02 472 SUPERFAMILY SSF48173 195 466 7.72E-101 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CVS48_RS17195 a6f7095b56f479284c0a6c62b826b455 262 Gene3D G3DSA:3.40.1280.10 109 257 6.3E-41 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CVS48_RS17195 a6f7095b56f479284c0a6c62b826b455 262 SUPERFAMILY SSF75217 111 258 2.16E-37 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CVS48_RS17195 a6f7095b56f479284c0a6c62b826b455 262 Gene3D G3DSA:3.30.1330.30 3 102 2.2E-9 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CVS48_RS17195 a6f7095b56f479284c0a6c62b826b455 262 SUPERFAMILY SSF55315 2 99 2.24E-9 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CVS48_RS17195 a6f7095b56f479284c0a6c62b826b455 262 Pfam PF00588 SpoU rRNA Methylase family 113 250 1.1E-30 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CVS48_RS10380 e834c21e08900d4906acfdb9caccd592 468 Gene3D G3DSA:3.50.50.60 1 208 3.1E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10380 e834c21e08900d4906acfdb9caccd592 468 Gene3D G3DSA:3.90.700.10 259 398 6.5E-30 T 29-03-2018 CVS48_RS10380 e834c21e08900d4906acfdb9caccd592 468 SUPERFAMILY SSF51905 394 460 4.22E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10380 e834c21e08900d4906acfdb9caccd592 468 SUPERFAMILY SSF51905 2 230 4.22E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10380 e834c21e08900d4906acfdb9caccd592 468 Pfam PF00890 FAD binding domain 3 431 1.3E-34 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS10380 e834c21e08900d4906acfdb9caccd592 468 SUPERFAMILY SSF56425 263 400 4.19E-24 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS10380 e834c21e08900d4906acfdb9caccd592 468 TIGRFAM TIGR02485 CobZ_N-term: precorrin 3B synthase CobZ 2 459 9.7E-215 T 29-03-2018 IPR012831 Precorrin 3B synthase CobZ CVS48_RS10870 66981778fabaa34315ab5c21dac3c58e 310 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CVS48_RS10870 66981778fabaa34315ab5c21dac3c58e 310 SUPERFAMILY SSF53271 65 300 6.16E-65 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CVS48_RS10870 66981778fabaa34315ab5c21dac3c58e 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 308 4.8E-119 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CVS48_RS10870 66981778fabaa34315ab5c21dac3c58e 310 Pfam PF14572 Phosphoribosyl synthetase-associated domain 199 308 2.3E-28 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CVS48_RS10870 66981778fabaa34315ab5c21dac3c58e 310 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 1 309 47.378 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CVS48_RS10870 66981778fabaa34315ab5c21dac3c58e 310 SMART SM01400 1 117 3.1E-70 T 29-03-2018 CVS48_RS10870 66981778fabaa34315ab5c21dac3c58e 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 1.6E-46 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CVS48_RS10870 66981778fabaa34315ab5c21dac3c58e 310 Gene3D G3DSA:3.40.50.2020 154 285 5.8E-41 T 29-03-2018 CVS48_RS10870 66981778fabaa34315ab5c21dac3c58e 310 Gene3D G3DSA:3.40.50.2020 1 153 9.7E-63 T 29-03-2018 CVS48_RS19635 76847b5ff92e9731495fc55889005186 357 SUPERFAMILY SSF56935 23 357 1.38E-70 T 29-03-2018 CVS48_RS19635 76847b5ff92e9731495fc55889005186 357 Pfam PF13609 Gram-negative porin 9 333 1.7E-43 T 29-03-2018 CVS48_RS19635 76847b5ff92e9731495fc55889005186 357 Gene3D G3DSA:2.40.160.10 25 357 6.2E-63 T 29-03-2018 CVS48_RS13375 4ccebd1e04a5ae9e90f48610b2373f48 534 PIRSF PIRSF002741 1 534 4.3E-139 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS13375 4ccebd1e04a5ae9e90f48610b2373f48 534 Gene3D G3DSA:3.90.76.10 53 154 2.1E-30 T 29-03-2018 CVS48_RS13375 4ccebd1e04a5ae9e90f48610b2373f48 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 437 1.9E-89 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS13375 4ccebd1e04a5ae9e90f48610b2373f48 534 Gene3D G3DSA:3.40.190.10 155 298 6.2E-40 T 29-03-2018 CVS48_RS13375 4ccebd1e04a5ae9e90f48610b2373f48 534 Gene3D G3DSA:3.10.105.10 299 502 4.6E-49 T 29-03-2018 CVS48_RS13375 4ccebd1e04a5ae9e90f48610b2373f48 534 SUPERFAMILY SSF53850 34 528 1.09E-132 T 29-03-2018 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 Gene3D G3DSA:1.20.120.160 4 177 2.8E-28 T 29-03-2018 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 Pfam PF00072 Response regulator receiver domain 678 790 1.1E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 Gene3D G3DSA:2.30.30.40 585 648 6.1E-14 T 29-03-2018 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 Gene3D G3DSA:2.30.30.40 517 584 0.11 T 29-03-2018 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 SMART SM00448 676 790 2.2E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 SMART SM00387 374 517 3.1E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 SUPERFAMILY SSF55874 333 515 3.93E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 SUPERFAMILY SSF52172 675 795 5.41E-32 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 516 2.4E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 Gene3D G3DSA:3.30.565.10 255 516 5.5E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 SMART SM00073 8 105 6.9E-14 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 Gene3D G3DSA:3.40.50.2300 669 798 2.2E-33 T 29-03-2018 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 Pfam PF01584 CheW-like domain 523 650 6.8E-16 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 495 6.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 433 6.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 514 6.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 SMART SM00260 509 648 8.3E-9 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 Pfam PF01627 Hpt domain 11 102 2.3E-14 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 SUPERFAMILY SSF50341 516 648 1.31E-22 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS20675 14b6ae1f2fcca0efe9b7e9403c802bfc 799 SUPERFAMILY SSF47226 8 104 7.46E-23 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS04815 7fdfc0c7d9e85d8077fac87d1e8e09c3 420 SUPERFAMILY SSF53822 56 416 1.24E-96 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS04815 7fdfc0c7d9e85d8077fac87d1e8e09c3 420 Gene3D G3DSA:3.40.50.2300 189 338 1.5E-34 T 29-03-2018 CVS48_RS04815 7fdfc0c7d9e85d8077fac87d1e8e09c3 420 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 57 415 1.0E-161 T 29-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like CVS48_RS04815 7fdfc0c7d9e85d8077fac87d1e8e09c3 420 Pfam PF13433 Periplasmic binding protein domain 58 417 7.5E-133 T 29-03-2018 CVS48_RS04815 7fdfc0c7d9e85d8077fac87d1e8e09c3 420 Gene3D G3DSA:3.40.50.2300 40 188 7.5E-19 T 29-03-2018 CVS48_RS23750 6ad5b6d80d2b8f7316fe3305f7d1fefb 469 Gene3D G3DSA:3.40.50.720 145 268 3.5E-12 T 29-03-2018 CVS48_RS23750 6ad5b6d80d2b8f7316fe3305f7d1fefb 469 Pfam PF13727 CoA-binding domain 68 243 9.9E-35 T 29-03-2018 CVS48_RS23750 6ad5b6d80d2b8f7316fe3305f7d1fefb 469 Pfam PF02397 Bacterial sugar transferase 279 460 1.5E-64 T 29-03-2018 IPR003362 Bacterial sugar transferase CVS48_RS23750 6ad5b6d80d2b8f7316fe3305f7d1fefb 469 SUPERFAMILY SSF51735 147 233 1.62E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23750 6ad5b6d80d2b8f7316fe3305f7d1fefb 469 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 22 469 2.5E-138 T 29-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CVS48_RS23750 6ad5b6d80d2b8f7316fe3305f7d1fefb 469 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 22 469 4.2E-155 T 29-03-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 CVS48_RS27590 1eb5b054d7a33e0b234b54a755aaccf0 405 Gene3D G3DSA:1.10.8.350 90 193 3.4E-30 T 29-03-2018 CVS48_RS27590 1eb5b054d7a33e0b234b54a755aaccf0 405 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 25 319 5.1E-108 T 29-03-2018 IPR011970 Lytic murein transglycosylase CVS48_RS27590 1eb5b054d7a33e0b234b54a755aaccf0 405 Gene3D G3DSA:1.10.101.10 323 402 2.5E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like CVS48_RS27590 1eb5b054d7a33e0b234b54a755aaccf0 405 Gene3D G3DSA:1.10.530.10 199 322 2.1E-34 T 29-03-2018 CVS48_RS27590 1eb5b054d7a33e0b234b54a755aaccf0 405 SUPERFAMILY SSF47090 323 395 1.36E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like CVS48_RS27590 1eb5b054d7a33e0b234b54a755aaccf0 405 Pfam PF01471 Putative peptidoglycan binding domain 337 392 6.7E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like CVS48_RS27590 1eb5b054d7a33e0b234b54a755aaccf0 405 Pfam PF13406 Transglycosylase SLT domain 26 316 1.1E-99 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 CVS48_RS27590 1eb5b054d7a33e0b234b54a755aaccf0 405 SUPERFAMILY SSF53955 11 323 1.17E-95 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS13290 86c687b3860f6da4d77569e831947a64 247 Pfam PF06299 Protein of unknown function (DUF1045) 60 220 6.9E-51 T 29-03-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS13290 86c687b3860f6da4d77569e831947a64 247 Gene3D G3DSA:3.90.1140.10 2 237 2.4E-22 T 29-03-2018 CVS48_RS13290 86c687b3860f6da4d77569e831947a64 247 PIRSF PIRSF033328 5 239 1.4E-43 T 29-03-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS04180 b88945b8d602121d981a83eeb74b5e7e 322 SUPERFAMILY SSF53850 109 280 4.07E-13 T 29-03-2018 CVS48_RS04180 b88945b8d602121d981a83eeb74b5e7e 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 2.9E-90 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04180 b88945b8d602121d981a83eeb74b5e7e 322 PIRSF PIRSF017082 1 321 6.1E-94 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04180 b88945b8d602121d981a83eeb74b5e7e 322 Gene3D G3DSA:3.40.190.10 121 249 3.7E-12 T 29-03-2018 CVS48_RS00145 18cfd54dc4493e916585362fa8c698b8 288 Gene3D G3DSA:1.10.10.10 5 84 7.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00145 18cfd54dc4493e916585362fa8c698b8 288 Gene3D G3DSA:3.30.450.40 91 287 1.4E-35 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS00145 18cfd54dc4493e916585362fa8c698b8 288 SUPERFAMILY SSF55781 89 276 4.19E-35 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS00145 18cfd54dc4493e916585362fa8c698b8 288 SMART SM00346 23 113 2.6E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS00145 18cfd54dc4493e916585362fa8c698b8 288 SUPERFAMILY SSF46785 23 97 4.23E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00145 18cfd54dc4493e916585362fa8c698b8 288 Pfam PF09339 IclR helix-turn-helix domain 25 75 8.5E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS00145 18cfd54dc4493e916585362fa8c698b8 288 Pfam PF01614 Bacterial transcriptional regulator 145 272 5.0E-9 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS04715 9620e03a122ee199407085ff562fad05 445 Pfam PF01061 ABC-2 type transporter 201 407 8.5E-11 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CVS48_RS04715 9620e03a122ee199407085ff562fad05 445 PRINTS PR00164 ABC-2 type transport system membrane protein signature 384 403 3.9E-6 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS04715 9620e03a122ee199407085ff562fad05 445 PRINTS PR00164 ABC-2 type transport system membrane protein signature 364 383 3.9E-6 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS04715 9620e03a122ee199407085ff562fad05 445 PRINTS PR00164 ABC-2 type transport system membrane protein signature 219 240 3.9E-6 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS14855 6ebc435c2b216604d2b2cbfbf767a18b 322 Gene3D G3DSA:3.30.200.20 1 102 1.3E-23 T 29-03-2018 CVS48_RS14855 6ebc435c2b216604d2b2cbfbf767a18b 322 SUPERFAMILY SSF56112 5 314 9.04E-69 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS14855 6ebc435c2b216604d2b2cbfbf767a18b 322 Gene3D G3DSA:3.90.1200.10 108 318 1.2E-20 T 29-03-2018 CVS48_RS14855 6ebc435c2b216604d2b2cbfbf767a18b 322 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 311 1.0E-91 T 29-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CVS48_RS14855 6ebc435c2b216604d2b2cbfbf767a18b 322 Pfam PF01636 Phosphotransferase enzyme family 27 262 4.8E-29 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CVS48_RS14855 6ebc435c2b216604d2b2cbfbf767a18b 322 Hamap MF_00301 Homoserine kinase [thrB]. 1 322 153.669 T 29-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CVS48_RS12430 bab1a58332f7dd18d6465ba5eb09cf52 209 Pfam PF04891 NifQ 42 205 3.9E-34 T 29-03-2018 IPR006975 NifQ GO:0009399|GO:0030151 CVS48_RS12650 4a97594093a558dd0c35a103131f348e 543 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 250 540 2.5E-129 T 29-03-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type CVS48_RS12650 4a97594093a558dd0c35a103131f348e 543 Gene3D G3DSA:1.25.10.10 5 176 0.0018 T 29-03-2018 IPR011989 Armadillo-like helical CVS48_RS12650 4a97594093a558dd0c35a103131f348e 543 SUPERFAMILY SSF48371 132 239 3.64E-8 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CVS48_RS12650 4a97594093a558dd0c35a103131f348e 543 Pfam PF02653 Branched-chain amino acid transport system / permease component 250 527 1.1E-50 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS12650 4a97594093a558dd0c35a103131f348e 543 SMART SM00567 E-Z type HEAT repeats 46 74 130.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CVS48_RS12650 4a97594093a558dd0c35a103131f348e 543 SMART SM00567 E-Z type HEAT repeats 135 164 1.8 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CVS48_RS12650 4a97594093a558dd0c35a103131f348e 543 SMART SM00567 E-Z type HEAT repeats 187 216 870.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CVS48_RS12650 4a97594093a558dd0c35a103131f348e 543 Gene3D G3DSA:1.10.3470.10 203 530 1.0E-48 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS21180 5a4431a8a6de10507a3b78fb6b5a361d 139 SMART SM00530 83 137 9.4E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS21180 5a4431a8a6de10507a3b78fb6b5a361d 139 SUPERFAMILY SSF47413 83 138 1.66E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS21180 5a4431a8a6de10507a3b78fb6b5a361d 139 Pfam PF01381 Helix-turn-helix 84 125 4.0E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS21180 5a4431a8a6de10507a3b78fb6b5a361d 139 Gene3D G3DSA:1.10.260.40 13 132 8.4E-11 T 29-03-2018 CVS48_RS22495 02e6754143339f56bed39ec670a97cf4 323 Pfam PF04773 FecR protein 119 209 1.2E-18 T 29-03-2018 IPR006860 FecR protein CVS48_RS22495 02e6754143339f56bed39ec670a97cf4 323 PIRSF PIRSF018266 1 321 2.2E-79 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS22495 02e6754143339f56bed39ec670a97cf4 323 Pfam PF16220 Domain of unknown function (DUF4880) 3 42 1.6E-13 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS27375 89b14d8b5c90f1ff67ed8f6c4eb04143 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 10 302 6.7E-125 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CVS48_RS27375 89b14d8b5c90f1ff67ed8f6c4eb04143 302 PIRSF PIRSF002936 1 302 8.7E-139 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CVS48_RS27375 89b14d8b5c90f1ff67ed8f6c4eb04143 302 SUPERFAMILY SSF52402 7 209 1.52E-61 T 29-03-2018 CVS48_RS27375 89b14d8b5c90f1ff67ed8f6c4eb04143 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 31 255 2.0E-45 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CVS48_RS27375 89b14d8b5c90f1ff67ed8f6c4eb04143 302 Gene3D G3DSA:3.40.50.620 3 267 8.3E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 647 0.0 T 29-03-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 Gene3D G3DSA:1.10.287.70 573 640 2.5E-16 T 29-03-2018 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 9.9E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 SUPERFAMILY SSF81442 43 558 1.05E-178 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 503 1.5E-137 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12450 610e065c464827031e5ea6825da444f9 658 Gene3D G3DSA:1.20.210.10 43 561 2.9E-186 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS28545 0e578904f227ca973a6ac89697471e05 89 PIRSF PIRSF003113 1 89 1.8E-21 T 29-03-2018 IPR002634 BolA protein CVS48_RS28545 0e578904f227ca973a6ac89697471e05 89 SUPERFAMILY SSF82657 7 88 8.76E-21 T 29-03-2018 IPR002634 BolA protein CVS48_RS28545 0e578904f227ca973a6ac89697471e05 89 Pfam PF01722 BolA-like protein 16 89 6.4E-25 T 29-03-2018 IPR002634 BolA protein CVS48_RS28545 0e578904f227ca973a6ac89697471e05 89 Gene3D G3DSA:3.30.300.90 3 89 1.1E-19 T 29-03-2018 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 SMART SM00846 3 155 1.9E-93 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 Gene3D G3DSA:3.30.360.10 165 317 1.4E-62 T 29-03-2018 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 SUPERFAMILY SSF51735 3 176 1.58E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 315 3.7E-63 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 Gene3D G3DSA:3.40.50.720 1 164 1.8E-74 T 29-03-2018 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 2.8E-39 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 2.8E-39 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 2.8E-39 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 2.8E-39 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 2.8E-39 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 327 1.2E-127 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 SUPERFAMILY SSF55347 155 316 2.29E-69 T 29-03-2018 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 PIRSF PIRSF000149 1 336 4.5E-135 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13135 cce0ec63ed2265c56d3908048716939d 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 106 8.3E-39 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS28985 87600014a479018a0049e85814c499e6 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 128 1.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS28985 87600014a479018a0049e85814c499e6 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 142 162 1.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS28985 87600014a479018a0049e85814c499e6 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 108 1.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS28985 87600014a479018a0049e85814c499e6 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 1.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS28985 87600014a479018a0049e85814c499e6 164 Gene3D G3DSA:1.10.10.10 1 163 1.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28985 87600014a479018a0049e85814c499e6 164 SUPERFAMILY SSF46785 24 162 1.77E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28985 87600014a479018a0049e85814c499e6 164 SMART SM00347 52 152 8.1E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS28985 87600014a479018a0049e85814c499e6 164 Pfam PF12802 MarR family 58 116 1.1E-10 T 29-03-2018 CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 Gene3D G3DSA:3.40.50.300 151 319 9.6E-24 T 29-03-2018 CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 Pfam PF00270 DEAD/DEAH box helicase 155 319 8.1E-12 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 SMART SM00487 148 349 4.9E-14 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 Pfam PF00271 Helicase conserved C-terminal domain 453 548 6.3E-5 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 SMART SM00490 452 549 1.9E-7 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 Gene3D G3DSA:3.40.50.300 344 590 1.1E-20 T 29-03-2018 CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 Hamap MF_00983 Probable primosomal protein N' [priA]. 18 696 23.768 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 TIGRFAM TIGR00595 priA: primosomal protein N' 173 694 6.7E-172 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 SUPERFAMILY SSF52540 169 397 1.18E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04070 8674a0e6bedea1c3f1e9c25ce09781eb 696 SUPERFAMILY SSF52540 463 559 1.18E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19980 76bfdeb3641fbd9878536bc4fb37534f 191 SUPERFAMILY SSF52980 83 189 1.07E-10 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CVS48_RS19980 76bfdeb3641fbd9878536bc4fb37534f 191 Pfam PF04471 Restriction endonuclease 81 186 1.3E-18 T 29-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CVS48_RS19980 76bfdeb3641fbd9878536bc4fb37534f 191 Gene3D G3DSA:3.40.1350.10 70 190 4.5E-12 T 29-03-2018 CVS48_RS26720 c01946fb2b36ce0e202338d37750ef77 566 Gene3D G3DSA:3.40.50.1010 109 350 1.2E-42 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS26720 c01946fb2b36ce0e202338d37750ef77 566 Gene3D G3DSA:3.40.50.300 351 559 4.4E-19 T 29-03-2018 CVS48_RS26720 c01946fb2b36ce0e202338d37750ef77 566 SUPERFAMILY SSF52540 351 544 2.03E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26720 c01946fb2b36ce0e202338d37750ef77 566 SUPERFAMILY SSF52540 232 288 2.03E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26720 c01946fb2b36ce0e202338d37750ef77 566 Pfam PF02562 PhoH-like protein 352 554 1.2E-52 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CVS48_RS26720 c01946fb2b36ce0e202338d37750ef77 566 SUPERFAMILY SSF88723 110 171 2.35E-11 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS26720 c01946fb2b36ce0e202338d37750ef77 566 SUPERFAMILY SSF88723 207 258 2.35E-11 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS26720 c01946fb2b36ce0e202338d37750ef77 566 Pfam PF13638 PIN domain 112 256 8.7E-40 T 29-03-2018 IPR002716 PIN domain CVS48_RS26720 c01946fb2b36ce0e202338d37750ef77 566 SMART SM00670 110 244 8.8E-13 T 29-03-2018 IPR002716 PIN domain CVS48_RS25190 a028ff8a361f0bfa915b9f76ef7fb1ab 69 SUPERFAMILY SSF50249 3 67 3.92E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS25190 a028ff8a361f0bfa915b9f76ef7fb1ab 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 67 3.4E-27 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS25190 a028ff8a361f0bfa915b9f76ef7fb1ab 69 PRINTS PR00050 Cold shock protein signature 27 36 3.9E-14 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS25190 a028ff8a361f0bfa915b9f76ef7fb1ab 69 PRINTS PR00050 Cold shock protein signature 42 60 3.9E-14 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS25190 a028ff8a361f0bfa915b9f76ef7fb1ab 69 PRINTS PR00050 Cold shock protein signature 6 21 3.9E-14 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS25190 a028ff8a361f0bfa915b9f76ef7fb1ab 69 PIRSF PIRSF002599 1 69 2.0E-21 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CVS48_RS25190 a028ff8a361f0bfa915b9f76ef7fb1ab 69 SMART SM00357 5 69 1.3E-25 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CVS48_RS25190 a028ff8a361f0bfa915b9f76ef7fb1ab 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 29-03-2018 IPR019844 Cold-shock conserved site CVS48_RS25190 a028ff8a361f0bfa915b9f76ef7fb1ab 69 Gene3D G3DSA:2.40.50.140 2 69 4.3E-25 T 29-03-2018 CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 4.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 4.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.1E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.1E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 SUPERFAMILY SSF51735 15 255 9.11E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 255 3.7E-52 T 29-03-2018 CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 Gene3D G3DSA:3.40.50.720 57 259 7.5E-52 T 29-03-2018 CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 Gene3D G3DSA:3.40.50.720 8 56 3.6E-8 T 29-03-2018 CVS48_RS09580 0bb1274ddfc148a6310acf2ea033c5a9 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS19560 585091e0b30f06d769fe0c8704d34b2e 234 PIRSF PIRSF000005 2 217 2.4E-59 T 29-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 CVS48_RS19560 585091e0b30f06d769fe0c8704d34b2e 234 SUPERFAMILY SSF46626 126 214 4.42E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS19560 585091e0b30f06d769fe0c8704d34b2e 234 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 146 211 1.3E-7 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS19560 585091e0b30f06d769fe0c8704d34b2e 234 PRINTS PR00605 Class IC cytochrome C signature 190 212 4.7E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CVS48_RS19560 585091e0b30f06d769fe0c8704d34b2e 234 PRINTS PR00605 Class IC cytochrome C signature 40 51 4.7E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CVS48_RS19560 585091e0b30f06d769fe0c8704d34b2e 234 Pfam PF00034 Cytochrome c 35 93 7.1E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS19560 585091e0b30f06d769fe0c8704d34b2e 234 SUPERFAMILY SSF46626 40 111 2.17E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS19560 585091e0b30f06d769fe0c8704d34b2e 234 Gene3D G3DSA:1.10.760.10 13 108 9.2E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS19560 585091e0b30f06d769fe0c8704d34b2e 234 Gene3D G3DSA:1.10.760.10 112 215 2.4E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS11695 7e34de727ece1a8043a59f2e9358e1af 314 Pfam PF16220 Domain of unknown function (DUF4880) 13 54 1.6E-10 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS11695 7e34de727ece1a8043a59f2e9358e1af 314 PIRSF PIRSF018266 1 312 1.3E-80 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS11695 7e34de727ece1a8043a59f2e9358e1af 314 Pfam PF04773 FecR protein 105 199 1.1E-18 T 29-03-2018 IPR006860 FecR protein CVS48_RS03210 520558e1491a8b52c9b385a61ed1e9cc 631 SMART SM00955 235 516 1.1E-60 T 29-03-2018 CVS48_RS03210 520558e1491a8b52c9b385a61ed1e9cc 631 Pfam PF00773 RNB domain 474 514 5.4E-9 T 29-03-2018 CVS48_RS03210 520558e1491a8b52c9b385a61ed1e9cc 631 Pfam PF00773 RNB domain 238 470 1.4E-34 T 29-03-2018 CVS48_RS03210 520558e1491a8b52c9b385a61ed1e9cc 631 SUPERFAMILY SSF50249 229 566 6.28E-73 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS05805 03c6c744c11e5330fd2ebdf5f281b67e 304 Gene3D G3DSA:3.40.250.10 199 304 1.0E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS05805 03c6c744c11e5330fd2ebdf5f281b67e 304 SUPERFAMILY SSF52821 182 301 1.31E-21 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS05805 03c6c744c11e5330fd2ebdf5f281b67e 304 Pfam PF00581 Rhodanese-like domain 207 299 3.1E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS05805 03c6c744c11e5330fd2ebdf5f281b67e 304 SMART SM00450 206 303 8.5E-9 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS05805 03c6c744c11e5330fd2ebdf5f281b67e 304 Pfam PF09335 SNARE associated Golgi protein 29 152 9.1E-14 T 29-03-2018 IPR032816 SNARE associated Golgi protein CVS48_RS26060 10ad4dc9922faa8912e7c4a7cae06585 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 102 203 4.4E-14 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS26060 10ad4dc9922faa8912e7c4a7cae06585 237 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 12 193 1.4E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS26060 10ad4dc9922faa8912e7c4a7cae06585 237 Gene3D G3DSA:3.40.50.1000 88 234 5.9E-26 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS26060 10ad4dc9922faa8912e7c4a7cae06585 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 111 183 1.6E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS26060 10ad4dc9922faa8912e7c4a7cae06585 237 SUPERFAMILY SSF56784 9 231 1.68E-41 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS26060 10ad4dc9922faa8912e7c4a7cae06585 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 192 205 1.0E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS26060 10ad4dc9922faa8912e7c4a7cae06585 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 117 130 1.0E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS26060 10ad4dc9922faa8912e7c4a7cae06585 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 1.0E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS26060 10ad4dc9922faa8912e7c4a7cae06585 237 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 11 207 2.7E-39 T 29-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 CVS48_RS14320 b1f95db7f06bbc17c99fded951a60e7a 208 Hamap MF_00528 Septum formation protein Maf [maf]. 13 207 29.74 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CVS48_RS14320 b1f95db7f06bbc17c99fded951a60e7a 208 Gene3D G3DSA:3.90.950.10 11 207 9.7E-63 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CVS48_RS14320 b1f95db7f06bbc17c99fded951a60e7a 208 TIGRFAM TIGR00172 maf: septum formation protein Maf 11 201 8.9E-45 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CVS48_RS14320 b1f95db7f06bbc17c99fded951a60e7a 208 Pfam PF02545 Maf-like protein 13 202 3.3E-52 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CVS48_RS14320 b1f95db7f06bbc17c99fded951a60e7a 208 SUPERFAMILY SSF52972 12 201 5.36E-58 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CVS48_RS14320 b1f95db7f06bbc17c99fded951a60e7a 208 PIRSF PIRSF006305 7 207 5.0E-48 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CVS48_RS22860 5d1981d5f5c19a459f53a2f8c281b384 191 Gene3D G3DSA:3.40.630.30 5 179 1.0E-22 T 29-03-2018 CVS48_RS22860 5d1981d5f5c19a459f53a2f8c281b384 191 SUPERFAMILY SSF55729 9 158 1.04E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS22860 5d1981d5f5c19a459f53a2f8c281b384 191 Pfam PF13302 Acetyltransferase (GNAT) domain 14 153 1.1E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS17585 c022391995395ebe3b6131e25a77821c 401 Gene3D G3DSA:3.40.50.10540 5 400 2.4E-124 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS17585 c022391995395ebe3b6131e25a77821c 401 Pfam PF02515 CoA-transferase family III 12 372 1.5E-114 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS17585 c022391995395ebe3b6131e25a77821c 401 SUPERFAMILY SSF89796 8 394 5.36E-124 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS12200 5df2d9a3d2874bb168bb6f9463ba55de 350 Pfam PF16344 Domain of unknown function (DUF4974) 253 315 4.1E-7 T 29-03-2018 IPR032508 Protein FecR, C-terminal CVS48_RS12200 5df2d9a3d2874bb168bb6f9463ba55de 350 Pfam PF16220 Domain of unknown function (DUF4880) 18 58 5.6E-9 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS12200 5df2d9a3d2874bb168bb6f9463ba55de 350 PIRSF PIRSF018266 6 336 1.2E-78 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS12200 5df2d9a3d2874bb168bb6f9463ba55de 350 Pfam PF04773 FecR protein 128 219 4.9E-20 T 29-03-2018 IPR006860 FecR protein CVS48_RS15285 f6aa33c371f55fa2d43fd768c03f90b1 369 SUPERFAMILY SSF48208 12 367 9.35E-76 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CVS48_RS15285 f6aa33c371f55fa2d43fd768c03f90b1 369 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 48 361 2.8E-37 T 29-03-2018 CVS48_RS15285 f6aa33c371f55fa2d43fd768c03f90b1 369 Gene3D G3DSA:1.50.10.10 6 369 1.6E-33 T 29-03-2018 CVS48_RS04440 753bbf1a30691db4a881b47ab4504ff1 472 Gene3D G3DSA:1.20.1250.20 267 457 2.1E-24 T 29-03-2018 CVS48_RS04440 753bbf1a30691db4a881b47ab4504ff1 472 Gene3D G3DSA:1.20.1250.20 20 208 9.8E-29 T 29-03-2018 CVS48_RS04440 753bbf1a30691db4a881b47ab4504ff1 472 SUPERFAMILY SSF103473 21 207 1.44E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS04440 753bbf1a30691db4a881b47ab4504ff1 472 SUPERFAMILY SSF103473 256 455 1.44E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS04440 753bbf1a30691db4a881b47ab4504ff1 472 Pfam PF07690 Major Facilitator Superfamily 28 417 1.4E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS09920 51c0c890fc3656ce2401700a90fc30e4 273 SUPERFAMILY SSF52540 25 265 1.98E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09920 51c0c890fc3656ce2401700a90fc30e4 273 PIRSF PIRSF039085 21 271 1.6E-92 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS09920 51c0c890fc3656ce2401700a90fc30e4 273 Pfam PF00005 ABC transporter 42 195 8.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS09920 51c0c890fc3656ce2401700a90fc30e4 273 SMART SM00382 50 270 2.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS09920 51c0c890fc3656ce2401700a90fc30e4 273 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS09920 51c0c890fc3656ce2401700a90fc30e4 273 Gene3D G3DSA:3.40.50.300 21 271 1.1E-69 T 29-03-2018 CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 Pfam PF01037 Lrp/AsnC ligand binding domain 73 147 3.0E-17 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 Gene3D G3DSA:1.10.10.10 7 58 7.0E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 SMART SM00344 7 116 2.8E-34 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 54 2.1E-17 T 29-03-2018 CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 SUPERFAMILY SSF54909 71 155 7.24E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 3.3E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 3.3E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 3.3E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 SUPERFAMILY SSF46785 7 64 7.49E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27815 c06120e817e8804a66132318eced19f0 156 Gene3D G3DSA:3.30.70.920 59 156 1.4E-19 T 29-03-2018 CVS48_RS07210 c572746c7687a5627175649638d42680 216 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 26 186 7.5E-46 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CVS48_RS07210 c572746c7687a5627175649638d42680 216 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 70 124 1.0E-15 T 29-03-2018 CVS48_RS07210 c572746c7687a5627175649638d42680 216 Pfam PF03099 Biotin/lipoate A/B protein ligase family 49 165 1.4E-8 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CVS48_RS07210 c572746c7687a5627175649638d42680 216 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 66 81 - T 29-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CVS48_RS07210 c572746c7687a5627175649638d42680 216 Hamap MF_00013 Octanoyltransferase [lipB]. 2 212 34.001 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CVS48_RS07210 c572746c7687a5627175649638d42680 216 Gene3D G3DSA:3.30.930.10 1 209 1.7E-51 T 29-03-2018 CVS48_RS07210 c572746c7687a5627175649638d42680 216 PIRSF PIRSF016262 1 214 3.2E-53 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CVS48_RS07210 c572746c7687a5627175649638d42680 216 SUPERFAMILY SSF55681 7 208 1.16E-56 T 29-03-2018 CVS48_RS08180 56f846a22b5e4dacf51b38975c7d76a1 253 Gene3D G3DSA:1.10.443.10 15 242 1.5E-26 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS08180 56f846a22b5e4dacf51b38975c7d76a1 253 SUPERFAMILY SSF56349 43 116 2.0E-24 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS08180 56f846a22b5e4dacf51b38975c7d76a1 253 SUPERFAMILY SSF56349 185 245 2.0E-24 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS08180 56f846a22b5e4dacf51b38975c7d76a1 253 Pfam PF00589 Phage integrase family 183 242 1.3E-9 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS05865 3903f54b73335d9d0746a1a9d156d7c6 288 SUPERFAMILY SSF161098 5 278 2.22E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05865 3903f54b73335d9d0746a1a9d156d7c6 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 278 1.2E-6 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05865 3903f54b73335d9d0746a1a9d156d7c6 288 Gene3D G3DSA:1.10.3720.10 6 281 4.7E-44 T 29-03-2018 CVS48_RS23165 c69f66b70a3c8e008288b8744fc6c16b 501 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 17 448 4.1E-117 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS23165 c69f66b70a3c8e008288b8744fc6c16b 501 Gene3D G3DSA:1.20.210.10 8 474 5.6E-94 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS23165 c69f66b70a3c8e008288b8744fc6c16b 501 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 13 467 1.4E-229 T 29-03-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CVS48_RS23165 c69f66b70a3c8e008288b8744fc6c16b 501 SUPERFAMILY SSF81442 15 470 4.45E-126 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS23165 c69f66b70a3c8e008288b8744fc6c16b 501 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 208 263 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12005 ba2f3656a1689e517c977d7bd7d5f1e6 227 Pfam PF03352 Methyladenine glycosylase 39 213 4.2E-67 T 29-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CVS48_RS12005 ba2f3656a1689e517c977d7bd7d5f1e6 227 Gene3D G3DSA:1.10.340.30 35 214 6.7E-70 T 29-03-2018 CVS48_RS12005 ba2f3656a1689e517c977d7bd7d5f1e6 227 SUPERFAMILY SSF48150 36 217 1.18E-66 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CVS48_RS08640 4525fdf1dc115d0825fb5b345abb1cd1 168 Pfam PF13279 Thioesterase-like superfamily 43 160 1.5E-15 T 29-03-2018 CVS48_RS08640 4525fdf1dc115d0825fb5b345abb1cd1 168 Gene3D G3DSA:3.10.129.10 19 164 1.9E-37 T 29-03-2018 CVS48_RS08640 4525fdf1dc115d0825fb5b345abb1cd1 168 SUPERFAMILY SSF54637 31 165 9.47E-36 T 29-03-2018 IPR029069 HotDog domain CVS48_RS03400 b3d23564961283582e27d40a82473865 135 Gene3D G3DSA:3.30.1330.40 2 135 1.1E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS03400 b3d23564961283582e27d40a82473865 135 SUPERFAMILY SSF55298 2 133 4.56E-33 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS03400 b3d23564961283582e27d40a82473865 135 Pfam PF01042 Endoribonuclease L-PSP 26 132 5.9E-22 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS07765 e2573b9911ae713c213a0579f007e2b3 210 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 13 180 1.2E-37 T 29-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related CVS48_RS07765 e2573b9911ae713c213a0579f007e2b3 210 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 8 181 2.9E-37 T 29-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 CVS48_RS05485 870ebad2519d144c94f8166e219510c0 208 Pfam PF01810 LysE type translocator 16 205 8.1E-38 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS05485 870ebad2519d144c94f8166e219510c0 208 PIRSF PIRSF006324 1 208 4.3E-53 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 SMART SM00052 434 680 3.2E-120 T 29-03-2018 IPR001633 EAL domain CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 SMART SM00267 253 424 5.0E-64 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 Pfam PF00990 Diguanylate cyclase, GGDEF domain 264 417 3.3E-48 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 Pfam PF00563 EAL domain 441 675 5.4E-74 T 29-03-2018 IPR001633 EAL domain CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 SUPERFAMILY SSF55073 269 426 2.04E-51 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 Gene3D G3DSA:3.30.70.270 258 430 2.8E-62 T 29-03-2018 CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 262 418 4.5E-42 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 SUPERFAMILY SSF141868 440 685 3.4E-90 T 29-03-2018 IPR001633 EAL domain CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 Gene3D G3DSA:3.20.20.450 431 683 1.1E-100 T 29-03-2018 IPR001633 EAL domain CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 Pfam PF03707 Bacterial signalling protein N terminal repeat 183 246 2.2E-10 T 29-03-2018 IPR005330 MHYT domain CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 Pfam PF03707 Bacterial signalling protein N terminal repeat 116 171 2.0E-16 T 29-03-2018 IPR005330 MHYT domain CVS48_RS10655 4f92e214f7b8597b2b1f8815057dba67 687 Pfam PF03707 Bacterial signalling protein N terminal repeat 53 110 1.2E-21 T 29-03-2018 IPR005330 MHYT domain CVS48_RS18550 4b61dd8af74db75f5fc2577cde8f0de6 141 Pfam PF00582 Universal stress protein family 1 140 1.3E-28 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS18550 4b61dd8af74db75f5fc2577cde8f0de6 141 SUPERFAMILY SSF52402 1 140 4.27E-33 T 29-03-2018 CVS48_RS18550 4b61dd8af74db75f5fc2577cde8f0de6 141 Gene3D G3DSA:3.40.50.620 1 141 2.6E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS18550 4b61dd8af74db75f5fc2577cde8f0de6 141 PRINTS PR01438 Universal stress protein signature 119 141 1.0E-17 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS18550 4b61dd8af74db75f5fc2577cde8f0de6 141 PRINTS PR01438 Universal stress protein signature 1 18 1.0E-17 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS18550 4b61dd8af74db75f5fc2577cde8f0de6 141 PRINTS PR01438 Universal stress protein signature 101 113 1.0E-17 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 Gene3D G3DSA:3.40.50.720 46 254 3.5E-62 T 29-03-2018 CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 Gene3D G3DSA:3.40.50.720 2 45 1.5E-6 T 29-03-2018 CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 4.2E-67 T 29-03-2018 CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 200 0.0081 T 29-03-2018 CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 SUPERFAMILY SSF51735 5 253 6.32E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 6.7E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 6.7E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21695 e0057987bab3b7a43c5aa301d14e0af6 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 6.7E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 Gene3D G3DSA:1.25.40.20 347 448 7.9E-13 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 SUPERFAMILY SSF48452 242 294 2.53E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 Gene3D G3DSA:1.25.40.20 449 766 2.1E-14 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 Gene3D G3DSA:1.25.40.10 209 325 1.0E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 SUPERFAMILY SSF48403 340 523 7.36E-22 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 Pfam PF13637 Ankyrin repeats (many copies) 354 405 7.3E-5 T 29-03-2018 CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 Gene3D G3DSA:3.40.50.970 81 208 0.0018 T 29-03-2018 CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 SMART SM00248 384 416 5.7 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 SMART SM00248 492 522 8.2 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS12435 706ab0b614aa6bb7ab7b319319a02116 827 SMART SM00248 457 488 2100.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 Gene3D G3DSA:3.40.50.720 1 260 9.5E-49 T 29-03-2018 CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 PIRSF PIRSF000126 1 259 2.5E-67 T 29-03-2018 CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 SUPERFAMILY SSF51735 2 222 1.14E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS20800 698432e874857dff1acd0ccadfcddede 260 Pfam PF00106 short chain dehydrogenase 5 193 5.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS00245 5bf30268ddcfa323a45e09f94d71e915 137 Pfam PF01042 Endoribonuclease L-PSP 28 134 3.7E-26 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS00245 5bf30268ddcfa323a45e09f94d71e915 137 Gene3D G3DSA:3.30.1330.40 25 137 1.1E-31 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS00245 5bf30268ddcfa323a45e09f94d71e915 137 SUPERFAMILY SSF55298 26 135 3.3E-34 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS08645 964b8b41c3ed8d42f2e640503d2afee2 525 Pfam PF00171 Aldehyde dehydrogenase family 58 515 5.6E-119 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS08645 964b8b41c3ed8d42f2e640503d2afee2 525 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 286 293 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS08645 964b8b41c3ed8d42f2e640503d2afee2 525 Gene3D G3DSA:3.40.309.10 303 483 1.1E-48 T 29-03-2018 CVS48_RS08645 964b8b41c3ed8d42f2e640503d2afee2 525 Gene3D G3DSA:3.40.605.10 31 302 1.9E-72 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS08645 964b8b41c3ed8d42f2e640503d2afee2 525 SUPERFAMILY SSF53720 34 521 1.96E-121 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS08645 964b8b41c3ed8d42f2e640503d2afee2 525 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 314 325 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 62 289 2.1E-62 T 29-03-2018 CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 201 220 5.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 181 189 5.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 140 5.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 SUPERFAMILY SSF51735 51 291 2.56E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 239 6.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 6.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 71 6.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 191 6.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 220 6.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 256 276 6.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 Gene3D G3DSA:3.40.50.720 12 294 7.3E-76 T 29-03-2018 CVS48_RS19040 c63f2cb3bab7f19f99f3026057a58dac 295 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 188 216 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS24780 32a94cdce80d366317fcb42cbcea7f40 221 Pfam PF11041 Protein of unknown function (DUF2612) 12 191 2.0E-37 T 29-03-2018 IPR021283 Protein of unknown function DUF2612 CVS48_RS03660 1c82dc648d138cd3b0afb8b4a3c71b59 282 SUPERFAMILY SSF53850 14 261 1.97E-23 T 29-03-2018 CVS48_RS03660 1c82dc648d138cd3b0afb8b4a3c71b59 282 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 50 265 4.4E-16 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS03660 1c82dc648d138cd3b0afb8b4a3c71b59 282 Gene3D G3DSA:3.40.190.10 38 213 5.0E-18 T 29-03-2018 CVS48_RS15935 4a0bb76e3e5977f012730d0d704e82e1 395 Gene3D G3DSA:3.30.9.10 164 321 1.4E-29 T 29-03-2018 CVS48_RS15935 4a0bb76e3e5977f012730d0d704e82e1 395 Gene3D G3DSA:3.40.50.720 1 93 3.0E-5 T 29-03-2018 CVS48_RS15935 4a0bb76e3e5977f012730d0d704e82e1 395 Gene3D G3DSA:3.30.9.10 94 163 3.6E-8 T 29-03-2018 CVS48_RS15935 4a0bb76e3e5977f012730d0d704e82e1 395 Pfam PF01266 FAD dependent oxidoreductase 5 360 3.6E-57 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS15935 4a0bb76e3e5977f012730d0d704e82e1 395 SUPERFAMILY SSF51905 322 386 4.27E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS15935 4a0bb76e3e5977f012730d0d704e82e1 395 SUPERFAMILY SSF51905 4 222 4.27E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 186 5.4E-5 T 29-03-2018 CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.2E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.2E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.2E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 7.2E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.2E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.2E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 5.8E-69 T 29-03-2018 CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 Gene3D G3DSA:3.40.50.720 46 250 1.9E-67 T 29-03-2018 CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 Gene3D G3DSA:3.40.50.720 1 45 9.9E-12 T 29-03-2018 CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 SUPERFAMILY SSF51735 7 249 1.55E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 5.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11200 62c5cb65d171ce571dc079de92945c4a 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 Gene3D G3DSA:3.40.50.1170 5 215 1.1E-54 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 PIRSF PIRSF500176 6 333 6.6E-79 T 29-03-2018 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 3 334 2.2E-118 T 29-03-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 SMART SM00870 8 328 2.1E-124 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 PIRSF PIRSF001220 3 333 5.7E-85 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 SUPERFAMILY SSF53774 5 333 4.71E-95 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 89 99 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 Gene3D G3DSA:3.40.50.40 222 333 5.1E-29 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 11 19 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 PRINTS PR00139 Asparaginase/glutaminase family signature 9 20 2.3E-22 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 PRINTS PR00139 Asparaginase/glutaminase family signature 88 106 2.3E-22 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 PRINTS PR00139 Asparaginase/glutaminase family signature 268 286 2.3E-22 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CVS48_RS06175 d6b5b18dd77992e4d47deb126329a6ca 334 Pfam PF00710 Asparaginase, N-terminal 9 191 2.7E-56 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CVS48_RS05330 9f598ca537d7fdd23dfe849831a5908c 535 SUPERFAMILY SSF53850 23 518 5.43E-126 T 29-03-2018 CVS48_RS05330 9f598ca537d7fdd23dfe849831a5908c 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 450 2.2E-89 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS05330 9f598ca537d7fdd23dfe849831a5908c 535 Gene3D G3DSA:3.90.76.10 38 182 1.2E-35 T 29-03-2018 CVS48_RS05330 9f598ca537d7fdd23dfe849831a5908c 535 Gene3D G3DSA:3.40.190.10 184 294 6.9E-25 T 29-03-2018 CVS48_RS05330 9f598ca537d7fdd23dfe849831a5908c 535 PIRSF PIRSF002741 1 528 3.4E-89 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS05330 9f598ca537d7fdd23dfe849831a5908c 535 Gene3D G3DSA:3.10.105.10 295 507 2.8E-45 T 29-03-2018 CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 PRINTS PR00811 Bacterial general secretion pathway protein D signature 524 542 8.3E-5 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 PRINTS PR00811 Bacterial general secretion pathway protein D signature 547 561 8.3E-5 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 PRINTS PR00811 Bacterial general secretion pathway protein D signature 393 417 8.3E-5 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 PRINTS PR00811 Bacterial general secretion pathway protein D signature 331 341 8.3E-5 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 PRINTS PR00811 Bacterial general secretion pathway protein D signature 428 438 8.3E-5 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 Gene3D G3DSA:1.25.40.120 27 400 1.5E-4 T 29-03-2018 CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 SMART SM00965 207 258 0.0059 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 Pfam PF00263 Bacterial type II and III secretion system protein 397 558 2.9E-39 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 Pfam PF03958 Bacterial type II/III secretion system short domain 271 330 3.6E-11 T 29-03-2018 IPR005644 NolW-like CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 PRINTS PR01032 Gene IV protein signature 487 515 3.2E-5 T 29-03-2018 CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 PRINTS PR01032 Gene IV protein signature 540 562 3.2E-5 T 29-03-2018 CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 PRINTS PR01032 Gene IV protein signature 377 400 3.2E-5 T 29-03-2018 CVS48_RS01040 f2f14542e34ae89e8c2533037a6bbd1d 615 PRINTS PR01032 Gene IV protein signature 418 441 3.2E-5 T 29-03-2018 CVS48_RS16155 dceee6df31c1c5aa73935af64094be45 232 Gene3D G3DSA:3.30.1360.100 142 224 6.0E-14 T 29-03-2018 IPR023229 Type II secretion system protein M, periplasmic domain CVS48_RS16155 dceee6df31c1c5aa73935af64094be45 232 Pfam PF04612 Type II secretion system (T2SS), protein M 60 223 1.1E-25 T 29-03-2018 IPR007690 Type II secretion system, protein M GO:0009306 CVS48_RS16155 dceee6df31c1c5aa73935af64094be45 232 SUPERFAMILY SSF103054 143 208 1.18E-6 T 29-03-2018 IPR023229 Type II secretion system protein M, periplasmic domain CVS48_RS05090 615162e7e9ceb00f955674e04f84e448 422 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.0E-170 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS05090 615162e7e9ceb00f955674e04f84e448 422 Gene3D G3DSA:3.65.10.10 221 418 3.7E-43 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS05090 615162e7e9ceb00f955674e04f84e448 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 405 1.3E-102 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS05090 615162e7e9ceb00f955674e04f84e448 422 SUPERFAMILY SSF55205 1 417 4.45E-137 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CVS48_RS05090 615162e7e9ceb00f955674e04f84e448 422 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 43.411 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS05090 615162e7e9ceb00f955674e04f84e448 422 Gene3D G3DSA:3.65.10.10 21 220 4.9E-49 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS28325 2a49fbd89a014ff31179d19fc072f3d0 328 SUPERFAMILY SSF53901 5 327 1.11E-67 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS28325 2a49fbd89a014ff31179d19fc072f3d0 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 6 328 68.991 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CVS48_RS28325 2a49fbd89a014ff31179d19fc072f3d0 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 7 328 1.6E-121 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CVS48_RS28325 2a49fbd89a014ff31179d19fc072f3d0 328 Gene3D G3DSA:3.40.47.10 172 328 5.8E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS28325 2a49fbd89a014ff31179d19fc072f3d0 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 9.9E-35 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CVS48_RS28325 2a49fbd89a014ff31179d19fc072f3d0 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 327 5.3E-34 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CVS48_RS28325 2a49fbd89a014ff31179d19fc072f3d0 328 Gene3D G3DSA:3.40.47.10 2 171 1.1E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS28665 f50aaf23f5a7ae69faba15a553ad753b 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 149 27.488 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28665 f50aaf23f5a7ae69faba15a553ad753b 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 6.3E-46 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28665 f50aaf23f5a7ae69faba15a553ad753b 162 Pfam PF12838 4Fe-4S dicluster domain 62 115 3.1E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS28665 f50aaf23f5a7ae69faba15a553ad753b 162 Gene3D G3DSA:3.30.70.20 107 155 1.2E-5 T 29-03-2018 CVS48_RS28665 f50aaf23f5a7ae69faba15a553ad753b 162 SUPERFAMILY SSF54862 36 144 3.85E-24 T 29-03-2018 CVS48_RS28665 f50aaf23f5a7ae69faba15a553ad753b 162 Gene3D G3DSA:3.30.70.20 21 73 4.8E-7 T 29-03-2018 CVS48_RS28665 f50aaf23f5a7ae69faba15a553ad753b 162 Gene3D G3DSA:3.30.70.20 74 106 3.6E-13 T 29-03-2018 CVS48_RS28665 f50aaf23f5a7ae69faba15a553ad753b 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS21655 647d3cc7e9770ddf377cce760977bbb0 100 SMART SM00530 11 66 1.1E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS21655 647d3cc7e9770ddf377cce760977bbb0 100 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 6 80 2.3E-23 T 29-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 CVS48_RS21655 647d3cc7e9770ddf377cce760977bbb0 100 SUPERFAMILY SSF47413 7 86 5.93E-22 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS21655 647d3cc7e9770ddf377cce760977bbb0 100 Gene3D G3DSA:1.10.260.40 6 91 1.5E-11 T 29-03-2018 CVS48_RS04630 75c9402cfdaebdeb3570ad884f8054c0 402 Gene3D G3DSA:3.90.1300.10 5 402 3.5E-101 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS04630 75c9402cfdaebdeb3570ad884f8054c0 402 Pfam PF01425 Amidase 23 386 9.4E-71 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS04630 75c9402cfdaebdeb3570ad884f8054c0 402 SUPERFAMILY SSF75304 16 398 2.62E-97 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 Gene3D G3DSA:1.10.357.10 539 664 3.3E-4 T 29-03-2018 CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 Pfam PF00271 Helicase conserved C-terminal domain 450 525 1.6E-5 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 SMART SM00487 145 345 3.3E-13 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 Gene3D G3DSA:3.40.50.300 151 329 3.0E-20 T 29-03-2018 CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 SUPERFAMILY SSF52540 161 310 4.42E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 SUPERFAMILY SSF52540 449 536 4.42E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 SUPERFAMILY SSF52540 358 414 4.42E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 Gene3D G3DSA:3.40.50.300 369 538 7.9E-12 T 29-03-2018 CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 SMART SM00490 443 526 8.7E-12 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS21465 1d112a2d6eb84a5a89c338717514181e 870 Pfam PF00270 DEAD/DEAH box helicase 151 297 2.0E-13 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS28750 9515ca7e343347f60fd9eef3d1865ccf 500 Gene3D G3DSA:3.10.105.10 270 469 1.6E-50 T 29-03-2018 CVS48_RS28750 9515ca7e343347f60fd9eef3d1865ccf 500 Gene3D G3DSA:3.90.76.10 32 169 3.1E-30 T 29-03-2018 CVS48_RS28750 9515ca7e343347f60fd9eef3d1865ccf 500 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 65 418 9.5E-85 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS28750 9515ca7e343347f60fd9eef3d1865ccf 500 PIRSF PIRSF002741 7 498 1.1E-104 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS28750 9515ca7e343347f60fd9eef3d1865ccf 500 Gene3D G3DSA:3.40.190.10 170 269 2.0E-25 T 29-03-2018 CVS48_RS28750 9515ca7e343347f60fd9eef3d1865ccf 500 SUPERFAMILY SSF53850 19 497 6.29E-131 T 29-03-2018 CVS48_RS17245 d8253f14bca7205b08e5cdf499157716 157 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 145 7.8E-52 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CVS48_RS17245 d8253f14bca7205b08e5cdf499157716 157 Pfam PF01668 SmpB protein 3 146 2.6E-57 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CVS48_RS17245 d8253f14bca7205b08e5cdf499157716 157 SUPERFAMILY SSF74982 3 127 4.19E-48 T 29-03-2018 IPR023620 Small protein B CVS48_RS17245 d8253f14bca7205b08e5cdf499157716 157 Gene3D G3DSA:2.40.280.10 3 122 7.2E-46 T 29-03-2018 IPR023620 Small protein B CVS48_RS17245 d8253f14bca7205b08e5cdf499157716 157 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 127 6.0E-64 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CVS48_RS17245 d8253f14bca7205b08e5cdf499157716 157 Hamap MF_00023 SsrA-binding protein [smpB]. 1 150 70.867 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CVS48_RS17245 d8253f14bca7205b08e5cdf499157716 157 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site CVS48_RS07050 f6b21e3a019b06c2007d925280c764f2 334 SUPERFAMILY SSF55347 126 283 8.28E-16 T 29-03-2018 CVS48_RS07050 f6b21e3a019b06c2007d925280c764f2 334 Gene3D G3DSA:3.30.360.10 130 334 4.4E-24 T 29-03-2018 CVS48_RS07050 f6b21e3a019b06c2007d925280c764f2 334 Gene3D G3DSA:3.40.50.720 1 129 2.5E-24 T 29-03-2018 CVS48_RS07050 f6b21e3a019b06c2007d925280c764f2 334 SUPERFAMILY SSF51735 2 157 2.31E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07050 f6b21e3a019b06c2007d925280c764f2 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 110 6.7E-9 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 Gene3D G3DSA:2.102.10.10 37 155 3.8E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 SUPERFAMILY SSF50022 18 164 1.44E-37 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 Pfam PF00355 Rieske [2Fe-2S] domain 47 131 1.0E-15 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 SUPERFAMILY SSF55961 166 441 2.83E-49 T 29-03-2018 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 Gene3D G3DSA:3.90.380.10 156 442 2.8E-53 T 29-03-2018 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 150 176 1.7E-30 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 192 214 1.7E-30 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 104 124 1.7E-30 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 82 102 1.7E-30 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 31 56 1.7E-30 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 61 76 1.7E-30 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS13605 a1e1d5613bff32871a8763d0c9d8ff3b 442 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 203 406 5.1E-16 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CVS48_RS06505 da6859b363617c6938b19835f36d048b 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 1.1E-28 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06505 da6859b363617c6938b19835f36d048b 101 Gene3D G3DSA:4.10.830.10 1 101 5.3E-35 T 29-03-2018 CVS48_RS06505 da6859b363617c6938b19835f36d048b 101 SUPERFAMILY SSF57716 2 101 1.92E-39 T 29-03-2018 CVS48_RS06505 da6859b363617c6938b19835f36d048b 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 27.606 T 29-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CVS48_RS18285 c9c6cf634608e71067916ac69fafb528 501 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 421 4.3E-73 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS18285 c9c6cf634608e71067916ac69fafb528 501 PIRSF PIRSF002741 3 492 5.4E-90 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS18285 c9c6cf634608e71067916ac69fafb528 501 Gene3D G3DSA:3.10.105.10 277 474 1.3E-42 T 29-03-2018 CVS48_RS18285 c9c6cf634608e71067916ac69fafb528 501 Gene3D G3DSA:3.40.190.10 181 276 1.0E-24 T 29-03-2018 CVS48_RS18285 c9c6cf634608e71067916ac69fafb528 501 Gene3D G3DSA:3.90.76.10 39 180 4.0E-31 T 29-03-2018 CVS48_RS18285 c9c6cf634608e71067916ac69fafb528 501 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 78 99 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CVS48_RS18285 c9c6cf634608e71067916ac69fafb528 501 SUPERFAMILY SSF53850 26 501 8.51E-113 T 29-03-2018 CVS48_RS21800 93ce73249894d2d460074b76840fef5b 314 PIRSF PIRSF015283 1 235 2.6E-66 T 29-03-2018 IPR016631 Regulatory, RpfE CVS48_RS21800 93ce73249894d2d460074b76840fef5b 314 PIRSF PIRSF015283 224 310 2.4E-8 T 29-03-2018 IPR016631 Regulatory, RpfE CVS48_RS26580 17521195dc910e7eaaa93405387db661 230 SUPERFAMILY SSF81342 4 188 1.8E-35 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CVS48_RS26580 17521195dc910e7eaaa93405387db661 230 Gene3D G3DSA:1.20.950.20 1 194 4.1E-32 T 29-03-2018 CVS48_RS26580 17521195dc910e7eaaa93405387db661 230 Pfam PF01292 Prokaryotic cytochrome b561 11 180 3.0E-19 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CVS48_RS21215 e0e7e00838f4b8b7bb0897a0fbfb97f6 342 Gene3D G3DSA:3.40.190.10 137 247 5.9E-8 T 29-03-2018 CVS48_RS21215 e0e7e00838f4b8b7bb0897a0fbfb97f6 342 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 63 334 4.2E-70 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21215 e0e7e00838f4b8b7bb0897a0fbfb97f6 342 SUPERFAMILY SSF53850 133 291 6.88E-7 T 29-03-2018 CVS48_RS21215 e0e7e00838f4b8b7bb0897a0fbfb97f6 342 PIRSF PIRSF017082 4 338 1.7E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 6.6E-68 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 6.6E-68 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 6.6E-68 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 6.6E-68 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 6.6E-68 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 6.6E-68 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 6.6E-68 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 6.6E-68 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 6.6E-68 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PIRSF PIRSF000350 1 461 1.3E-74 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 SUPERFAMILY SSF51905 3 339 6.55E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 Gene3D G3DSA:3.50.50.60 164 283 4.2E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 329 9.0E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 Gene3D G3DSA:3.50.50.60 4 163 2.9E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 Gene3D G3DSA:3.50.50.60 284 358 2.1E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.4E-35 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.4E-35 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 1.4E-35 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.4E-35 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 1.4E-35 T 29-03-2018 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 467 1.3E-142 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 457 9.0E-29 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 Gene3D G3DSA:3.30.390.30 359 467 4.0E-33 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS16085 1aa00942d84a52ef5c771c7b2bf4a2c1 467 SUPERFAMILY SSF55424 347 466 9.79E-32 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS13250 84be30a29086356e70d7785903dad17e 283 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 5 253 2.7E-85 T 29-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 CVS48_RS13250 84be30a29086356e70d7785903dad17e 283 Pfam PF00005 ABC transporter 21 184 6.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13250 84be30a29086356e70d7785903dad17e 283 SMART SM00382 30 241 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13250 84be30a29086356e70d7785903dad17e 283 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13250 84be30a29086356e70d7785903dad17e 283 Gene3D G3DSA:3.40.50.300 1 275 3.3E-56 T 29-03-2018 CVS48_RS13250 84be30a29086356e70d7785903dad17e 283 SUPERFAMILY SSF52540 4 244 1.94E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28695 3ee3b08c689265514bda00204169eb7a 208 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 130 151 - T 29-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28695 3ee3b08c689265514bda00204169eb7a 208 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 96 157 3.0E-22 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28695 3ee3b08c689265514bda00204169eb7a 208 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 1 177 33.045 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28695 3ee3b08c689265514bda00204169eb7a 208 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 31 168 6.9E-37 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28695 3ee3b08c689265514bda00204169eb7a 208 SUPERFAMILY SSF143243 21 190 1.26E-49 T 29-03-2018 CVS48_RS28695 3ee3b08c689265514bda00204169eb7a 208 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 32 170 3.4E-41 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 SUPERFAMILY SSF52540 298 520 1.1E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 SMART SM00382 26 228 4.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 SMART SM00382 341 508 8.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 Pfam PF00005 ABC transporter 17 177 2.6E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 Pfam PF00005 ABC transporter 332 463 9.1E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 ProSitePatterns PS00211 ABC transporters family signature. 435 449 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 Pfam PF12848 ABC transporter 216 291 4.7E-23 T 29-03-2018 IPR032781 ABC-transporter extension domain CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 Gene3D G3DSA:3.40.50.300 2 278 1.3E-47 T 29-03-2018 CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 Gene3D G3DSA:1.20.58.410 562 641 5.2E-8 T 29-03-2018 CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 SUPERFAMILY SSF52540 2 229 1.41E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22190 172d1f45a3867a017bf4decd9af64b1e 644 Gene3D G3DSA:3.40.50.300 311 561 1.2E-45 T 29-03-2018 CVS48_RS19205 6ea3682e8d59ec4bf26669ae3bce9cc1 402 SUPERFAMILY SSF53822 26 400 7.4E-79 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS19205 6ea3682e8d59ec4bf26669ae3bce9cc1 402 Pfam PF13458 Periplasmic binding protein 26 365 5.7E-78 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS19205 6ea3682e8d59ec4bf26669ae3bce9cc1 402 Gene3D G3DSA:3.40.50.2300 9 162 1.1E-12 T 29-03-2018 CVS48_RS19205 6ea3682e8d59ec4bf26669ae3bce9cc1 402 Gene3D G3DSA:3.40.50.2300 163 307 1.9E-34 T 29-03-2018 CVS48_RS10905 cbb2bf47a2caf33cbcf30a2569f0af8c 91 Gene3D G3DSA:3.30.420.10 2 90 2.1E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS10905 cbb2bf47a2caf33cbcf30a2569f0af8c 91 SUPERFAMILY SSF53098 5 89 3.54E-24 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS10905 cbb2bf47a2caf33cbcf30a2569f0af8c 91 Pfam PF13683 Integrase core domain 29 89 3.8E-26 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS06965 b8ed072e56ead40f6b86eeeb65884167 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 5.2E-7 T 29-03-2018 CVS48_RS06965 b8ed072e56ead40f6b86eeeb65884167 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 5.2E-7 T 29-03-2018 CVS48_RS06965 b8ed072e56ead40f6b86eeeb65884167 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 5.2E-7 T 29-03-2018 CVS48_RS06965 b8ed072e56ead40f6b86eeeb65884167 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 86 108 5.2E-7 T 29-03-2018 CVS48_RS06965 b8ed072e56ead40f6b86eeeb65884167 472 SUPERFAMILY SSF103473 5 205 6.15E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS06965 b8ed072e56ead40f6b86eeeb65884167 472 SUPERFAMILY SSF103473 262 463 6.15E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS06965 b8ed072e56ead40f6b86eeeb65884167 472 Gene3D G3DSA:1.20.1250.20 19 212 2.3E-27 T 29-03-2018 CVS48_RS06965 b8ed072e56ead40f6b86eeeb65884167 472 Gene3D G3DSA:1.20.1250.20 266 465 1.6E-27 T 29-03-2018 CVS48_RS06965 b8ed072e56ead40f6b86eeeb65884167 472 Pfam PF07690 Major Facilitator Superfamily 30 424 3.6E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS02330 2cb3acf0eb54b369aa44f828263f925d 362 Pfam PF09383 NIL domain 274 345 2.0E-14 T 29-03-2018 IPR018449 NIL domain CVS48_RS02330 2cb3acf0eb54b369aa44f828263f925d 362 SMART SM00930 272 347 3.9E-17 T 29-03-2018 IPR018449 NIL domain CVS48_RS02330 2cb3acf0eb54b369aa44f828263f925d 362 SMART SM00382 30 218 1.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS02330 2cb3acf0eb54b369aa44f828263f925d 362 Pfam PF00005 ABC transporter 21 169 7.1E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS02330 2cb3acf0eb54b369aa44f828263f925d 362 SUPERFAMILY SSF52540 1 239 4.52E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02330 2cb3acf0eb54b369aa44f828263f925d 362 Gene3D G3DSA:3.30.70.260 263 350 5.4E-18 T 29-03-2018 CVS48_RS02330 2cb3acf0eb54b369aa44f828263f925d 362 SUPERFAMILY SSF55021 272 349 3.66E-14 T 29-03-2018 CVS48_RS02330 2cb3acf0eb54b369aa44f828263f925d 362 Gene3D G3DSA:3.40.50.300 1 262 3.5E-81 T 29-03-2018 CVS48_RS02330 2cb3acf0eb54b369aa44f828263f925d 362 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 Pfam PF08345 Flagellar M-ring protein C-terminal 254 449 1.0E-44 T 29-03-2018 IPR013556 Flagellar M-ring C-terminal CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 Gene3D G3DSA:2.130.10.10 334 526 3.3E-6 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 17 557 2.2E-124 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 Pfam PF01514 Secretory protein of YscJ/FliF family 33 222 1.3E-75 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 PRINTS PR01009 Flagellar M-ring protein signature 155 169 3.3E-40 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 PRINTS PR01009 Flagellar M-ring protein signature 123 141 3.3E-40 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 PRINTS PR01009 Flagellar M-ring protein signature 198 216 3.3E-40 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 PRINTS PR01009 Flagellar M-ring protein signature 267 285 3.3E-40 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 PRINTS PR01009 Flagellar M-ring protein signature 377 401 3.3E-40 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 Gene3D G3DSA:3.30.70.1530 54 117 3.5E-9 T 29-03-2018 CVS48_RS17000 0e365b0f919d8a6db96e032e5bf0625b 559 PIRSF PIRSF004862 2 559 4.6E-148 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CVS48_RS25015 a650147714bf82da1ca97bb6fcd85326 501 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS25015 a650147714bf82da1ca97bb6fcd85326 501 Gene3D G3DSA:3.40.309.10 269 464 1.4E-68 T 29-03-2018 CVS48_RS25015 a650147714bf82da1ca97bb6fcd85326 501 Pfam PF00171 Aldehyde dehydrogenase family 15 478 2.2E-168 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS25015 a650147714bf82da1ca97bb6fcd85326 501 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS25015 a650147714bf82da1ca97bb6fcd85326 501 Gene3D G3DSA:3.40.605.10 2 268 1.2E-85 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS25015 a650147714bf82da1ca97bb6fcd85326 501 SUPERFAMILY SSF53720 7 482 1.26E-156 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS19810 692e024a7582e274928a8f9835339d5f 284 SUPERFAMILY SSF51261 65 281 1.73E-47 T 29-03-2018 IPR011055 Duplicated hybrid motif CVS48_RS19810 692e024a7582e274928a8f9835339d5f 284 Gene3D G3DSA:3.10.350.10 60 147 3.9E-18 T 29-03-2018 CVS48_RS19810 692e024a7582e274928a8f9835339d5f 284 SMART SM00257 64 108 7.9E-15 T 29-03-2018 IPR018392 LysM domain CVS48_RS19810 692e024a7582e274928a8f9835339d5f 284 Pfam PF01476 LysM domain 65 106 6.3E-14 T 29-03-2018 IPR018392 LysM domain CVS48_RS19810 692e024a7582e274928a8f9835339d5f 284 Gene3D G3DSA:2.70.70.10 148 284 8.4E-34 T 29-03-2018 CVS48_RS19810 692e024a7582e274928a8f9835339d5f 284 Pfam PF01551 Peptidase family M23 184 277 2.8E-29 T 29-03-2018 IPR016047 Peptidase M23 CVS48_RS10320 b6cc4fcbc00c0f271f1a1548dd5abbaf 252 Pfam PF01048 Phosphorylase superfamily 3 231 1.1E-46 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CVS48_RS10320 b6cc4fcbc00c0f271f1a1548dd5abbaf 252 SUPERFAMILY SSF53167 4 240 8.77E-58 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CVS48_RS10320 b6cc4fcbc00c0f271f1a1548dd5abbaf 252 Gene3D G3DSA:3.40.50.1580 1 246 2.1E-51 T 29-03-2018 CVS48_RS10320 b6cc4fcbc00c0f271f1a1548dd5abbaf 252 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 3 238 4.2E-36 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 Gene3D G3DSA:3.50.50.60 2 146 1.5E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 Gene3D G3DSA:3.50.50.60 147 297 2.2E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 SUPERFAMILY SSF51905 1 293 5.49E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 136 3.0E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 3.0E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 102 110 3.0E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 138 1.7E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 182 278 4.8E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.7E-14 T 29-03-2018 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 271 3.7E-14 T 29-03-2018 CVS48_RS19995 99eb829b358d8738547d5a112865ae18 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 3.7E-14 T 29-03-2018 CVS48_RS14430 04850d82584275eee5affbdc189492ac 177 Pfam PF02975 Methylamine dehydrogenase, L chain 57 165 4.6E-52 T 29-03-2018 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 CVS48_RS14430 04850d82584275eee5affbdc189492ac 177 Gene3D G3DSA:2.60.30.10 48 167 2.5E-57 T 29-03-2018 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 CVS48_RS14430 04850d82584275eee5affbdc189492ac 177 SUPERFAMILY SSF57561 53 167 3.27E-55 T 29-03-2018 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 CVS48_RS14430 04850d82584275eee5affbdc189492ac 177 PIRSF PIRSF000192 2 168 8.7E-47 T 29-03-2018 IPR016008 Amine dehydrogenase light chain GO:0009308|GO:0030058|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 CVS48_RS09085 d3e561771c231b5b6bdf8e6a96d1d091 277 Pfam PF05175 Methyltransferase small domain 106 188 5.6E-14 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CVS48_RS09085 d3e561771c231b5b6bdf8e6a96d1d091 277 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 20 267 2.0E-86 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CVS48_RS09085 d3e561771c231b5b6bdf8e6a96d1d091 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 16 271 1.0E-68 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CVS48_RS09085 d3e561771c231b5b6bdf8e6a96d1d091 277 Gene3D G3DSA:3.40.50.150 76 270 1.1E-43 T 29-03-2018 CVS48_RS09085 d3e561771c231b5b6bdf8e6a96d1d091 277 Gene3D G3DSA:1.10.8.10 2 75 5.9E-20 T 29-03-2018 CVS48_RS09085 d3e561771c231b5b6bdf8e6a96d1d091 277 SUPERFAMILY SSF53335 7 270 2.24E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS09085 d3e561771c231b5b6bdf8e6a96d1d091 277 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 177 183 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CVS48_RS09085 d3e561771c231b5b6bdf8e6a96d1d091 277 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 272 43.515 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CVS48_RS22610 9d4bd0f8a09b13e09cf1fe5a28c6f68a 266 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 6 254 7.8E-119 T 29-03-2018 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 CVS48_RS22610 9d4bd0f8a09b13e09cf1fe5a28c6f68a 266 Gene3D G3DSA:3.20.20.60 2 263 8.5E-51 T 29-03-2018 CVS48_RS22610 9d4bd0f8a09b13e09cf1fe5a28c6f68a 266 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 243 8.8E-61 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CVS48_RS22610 9d4bd0f8a09b13e09cf1fe5a28c6f68a 266 SUPERFAMILY SSF51621 3 259 2.3E-83 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS06920 fbb73a4b1bc3d8dfe7ea3752a58ea4ca 643 Gene3D G3DSA:3.40.47.10 192 375 6.7E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS06920 fbb73a4b1bc3d8dfe7ea3752a58ea4ca 643 Gene3D G3DSA:3.40.47.10 4 191 4.2E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS06920 fbb73a4b1bc3d8dfe7ea3752a58ea4ca 643 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 285 357 5.8E-9 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CVS48_RS06920 fbb73a4b1bc3d8dfe7ea3752a58ea4ca 643 Pfam PF14518 Iron-containing redox enzyme 513 630 1.4E-10 T 29-03-2018 IPR028201 PqqC-like protein CVS48_RS06920 fbb73a4b1bc3d8dfe7ea3752a58ea4ca 643 SUPERFAMILY SSF53901 253 370 2.11E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS06920 fbb73a4b1bc3d8dfe7ea3752a58ea4ca 643 SUPERFAMILY SSF48613 423 635 3.86E-27 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CVS48_RS06920 fbb73a4b1bc3d8dfe7ea3752a58ea4ca 643 Gene3D G3DSA:1.20.910.10 415 643 1.3E-31 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CVS48_RS06920 fbb73a4b1bc3d8dfe7ea3752a58ea4ca 643 SUPERFAMILY SSF53901 6 200 8.27E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS14490 2646c3f384c5e6e846c484af2a167047 876 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 32 725 3.7E-235 T 29-03-2018 IPR011853 TRAP transporter, 4TM/12TM fusion protein CVS48_RS14490 2646c3f384c5e6e846c484af2a167047 876 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 136 668 1.2E-69 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS14490 2646c3f384c5e6e846c484af2a167047 876 Pfam PF11874 Domain of unknown function (DUF3394) 674 859 5.6E-58 T 29-03-2018 IPR021814 Protein of unknown function DUF3394 CVS48_RS23455 cb6213e9611ced1e4f9d57be3f8c7adf 146 Pfam PF00571 CBS domain 73 124 4.5E-11 T 29-03-2018 IPR000644 CBS domain CVS48_RS23455 cb6213e9611ced1e4f9d57be3f8c7adf 146 Pfam PF00571 CBS domain 12 61 2.6E-10 T 29-03-2018 IPR000644 CBS domain CVS48_RS23455 cb6213e9611ced1e4f9d57be3f8c7adf 146 Gene3D G3DSA:3.10.580.10 1 139 2.2E-28 T 29-03-2018 CVS48_RS23455 cb6213e9611ced1e4f9d57be3f8c7adf 146 SUPERFAMILY SSF54631 3 141 3.66E-33 T 29-03-2018 CVS48_RS23455 cb6213e9611ced1e4f9d57be3f8c7adf 146 SMART SM00116 15 62 7.2E-7 T 29-03-2018 IPR000644 CBS domain CVS48_RS23455 cb6213e9611ced1e4f9d57be3f8c7adf 146 SMART SM00116 80 127 5.8E-7 T 29-03-2018 IPR000644 CBS domain CVS48_RS03345 ba648046ff51c3dc55bfe04ca945153a 221 SUPERFAMILY SSF51391 6 208 2.62E-54 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS03345 ba648046ff51c3dc55bfe04ca945153a 221 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 8 214 23.796 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS03345 ba648046ff51c3dc55bfe04ca945153a 221 Gene3D G3DSA:3.20.20.70 2 211 1.4E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS03345 ba648046ff51c3dc55bfe04ca945153a 221 Pfam PF02581 Thiamine monophosphate synthase 10 196 1.0E-49 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS03345 ba648046ff51c3dc55bfe04ca945153a 221 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 10 207 7.0E-47 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS20070 185cb57d6e9224bbfb7442882ca25188 325 SMART SM00382 45 224 4.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS20070 185cb57d6e9224bbfb7442882ca25188 325 Pfam PF00005 ABC transporter 37 178 3.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS20070 185cb57d6e9224bbfb7442882ca25188 325 Gene3D G3DSA:3.40.50.300 6 247 2.8E-67 T 29-03-2018 CVS48_RS20070 185cb57d6e9224bbfb7442882ca25188 325 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS20070 185cb57d6e9224bbfb7442882ca25188 325 SUPERFAMILY SSF52540 11 240 1.39E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 Pfam PF00175 Oxidoreductase NAD-binding domain 117 206 1.9E-4 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 241 311 5.3E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 269 277 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 Gene3D G3DSA:3.10.20.30 221 320 3.2E-20 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 116 135 6.2E-29 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 94 108 6.2E-29 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 192 200 6.2E-29 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 31 41 6.2E-29 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 141 150 6.2E-29 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 80 94 6.2E-29 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 SUPERFAMILY SSF52343 102 229 2.23E-28 T 29-03-2018 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 SUPERFAMILY SSF54292 216 319 1.06E-24 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 Gene3D G3DSA:3.40.50.80 107 220 7.4E-27 T 29-03-2018 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 Gene3D G3DSA:2.40.30.10 1 104 1.5E-15 T 29-03-2018 CVS48_RS20830 584ac70b3dcab27834da4f953c4a6714 320 SUPERFAMILY SSF63380 4 104 8.26E-22 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS15025 6a1008eb23f1cec19707f5074c7ed63e 238 Pfam PF14559 Tetratricopeptide repeat 83 138 1.7E-5 T 29-03-2018 CVS48_RS15025 6a1008eb23f1cec19707f5074c7ed63e 238 Gene3D G3DSA:1.25.40.10 68 231 5.0E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS15025 6a1008eb23f1cec19707f5074c7ed63e 238 SUPERFAMILY SSF48452 73 215 4.56E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 SUPERFAMILY SSF52540 4 254 1.39E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 SMART SM00382 31 233 4.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 SMART SM00382 307 498 1.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 Gene3D G3DSA:3.40.50.300 1 269 3.1E-68 T 29-03-2018 CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 Gene3D G3DSA:3.40.50.300 270 538 9.4E-75 T 29-03-2018 CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 SUPERFAMILY SSF52540 273 520 4.51E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 Pfam PF00005 ABC transporter 23 181 2.9E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 Pfam PF00005 ABC transporter 298 448 8.1E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 500 532 1.6E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 273 1.4E-6 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS28825 cf003da133b54ecc49a9a3ce4df2ab2f 551 ProSitePatterns PS00211 ABC transporters family signature. 421 435 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS18710 667bad02f0aacbbeee3e0d4c8902f116 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 66 1.2E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18710 667bad02f0aacbbeee3e0d4c8902f116 243 Pfam PF07729 FCD domain 77 213 2.0E-19 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS18710 667bad02f0aacbbeee3e0d4c8902f116 243 SUPERFAMILY SSF48008 72 220 2.59E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS18710 667bad02f0aacbbeee3e0d4c8902f116 243 SUPERFAMILY SSF46785 6 95 1.85E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18710 667bad02f0aacbbeee3e0d4c8902f116 243 Gene3D G3DSA:1.20.120.530 63 231 3.1E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS18710 667bad02f0aacbbeee3e0d4c8902f116 243 SMART SM00345 8 66 5.4E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS18710 667bad02f0aacbbeee3e0d4c8902f116 243 SMART SM00895 76 216 2.9E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS18710 667bad02f0aacbbeee3e0d4c8902f116 243 Gene3D G3DSA:1.10.10.10 2 62 2.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07175 64d5c315bcd286ec383d95594c238d0b 279 Pfam PF00005 ABC transporter 37 186 1.6E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07175 64d5c315bcd286ec383d95594c238d0b 279 Gene3D G3DSA:3.40.50.300 17 258 1.3E-58 T 29-03-2018 CVS48_RS07175 64d5c315bcd286ec383d95594c238d0b 279 SUPERFAMILY SSF52540 19 252 4.24E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07175 64d5c315bcd286ec383d95594c238d0b 279 SMART SM00382 45 243 2.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS18770 43f1cd68e43522cabe70054bd5d43f92 226 Pfam PF00149 Calcineurin-like phosphoesterase 42 128 2.7E-5 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS18770 43f1cd68e43522cabe70054bd5d43f92 226 PIRSF PIRSF000887 19 223 7.1E-44 T 29-03-2018 IPR024173 Phosphoesterase, MJ0037 CVS48_RS18770 43f1cd68e43522cabe70054bd5d43f92 226 Gene3D G3DSA:3.60.21.10 41 204 2.4E-12 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS18770 43f1cd68e43522cabe70054bd5d43f92 226 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 19 221 1.4E-58 T 29-03-2018 IPR026336 Metallophosphoesterase, DNA ligase-associated CVS48_RS18770 43f1cd68e43522cabe70054bd5d43f92 226 SUPERFAMILY SSF56300 42 176 2.2E-12 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS18695 3c3154cc2e363483a98c910b28435dd1 366 Gene3D G3DSA:2.60.120.10 11 331 4.6E-25 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS18695 3c3154cc2e363483a98c910b28435dd1 366 Pfam PF02311 AraC-like ligand binding domain 256 320 4.4E-7 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS18695 3c3154cc2e363483a98c910b28435dd1 366 SUPERFAMILY SSF51182 4 349 2.8E-53 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS12340 1f85e9de11345e29e50ffd41f308e5fc 310 Gene3D G3DSA:3.40.50.1820 4 296 2.2E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS12340 1f85e9de11345e29e50ffd41f308e5fc 310 Pfam PF12697 Alpha/beta hydrolase family 28 288 8.4E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS12340 1f85e9de11345e29e50ffd41f308e5fc 310 SUPERFAMILY SSF53474 12 294 4.13E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS12340 1f85e9de11345e29e50ffd41f308e5fc 310 PRINTS PR00412 Epoxide hydrolase signature 31 49 1.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS12340 1f85e9de11345e29e50ffd41f308e5fc 310 PRINTS PR00412 Epoxide hydrolase signature 270 292 1.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS12340 1f85e9de11345e29e50ffd41f308e5fc 310 PRINTS PR00412 Epoxide hydrolase signature 236 252 1.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS12340 1f85e9de11345e29e50ffd41f308e5fc 310 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS12340 1f85e9de11345e29e50ffd41f308e5fc 310 PRINTS PR00412 Epoxide hydrolase signature 51 66 1.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS18645 27fc91a8c915a16794f1e1ad4325b3be 517 Gene3D G3DSA:3.90.76.10 60 153 6.7E-25 T 29-03-2018 CVS48_RS18645 27fc91a8c915a16794f1e1ad4325b3be 517 Gene3D G3DSA:3.40.190.10 154 285 6.2E-35 T 29-03-2018 CVS48_RS18645 27fc91a8c915a16794f1e1ad4325b3be 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 429 3.6E-90 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS18645 27fc91a8c915a16794f1e1ad4325b3be 517 SUPERFAMILY SSF53850 32 497 3.8E-123 T 29-03-2018 CVS48_RS18645 27fc91a8c915a16794f1e1ad4325b3be 517 PIRSF PIRSF002741 1 505 2.8E-103 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS18645 27fc91a8c915a16794f1e1ad4325b3be 517 Gene3D G3DSA:3.10.105.10 286 482 1.5E-50 T 29-03-2018 CVS48_RS00555 fcc00571e625f44e496f256d9cd30378 165 Gene3D G3DSA:3.40.50.2300 3 145 2.7E-35 T 29-03-2018 CVS48_RS00555 fcc00571e625f44e496f256d9cd30378 165 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 133 5.5E-17 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CVS48_RS00555 fcc00571e625f44e496f256d9cd30378 165 SMART SM00226 7 145 7.3E-32 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CVS48_RS00555 fcc00571e625f44e496f256d9cd30378 165 SUPERFAMILY SSF52788 7 145 1.83E-38 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CVS48_RS16355 55563c4c5c5d4da1ebe23706e9a3e89c 207 Gene3D G3DSA:3.40.30.10 1 96 4.9E-31 T 29-03-2018 CVS48_RS16355 55563c4c5c5d4da1ebe23706e9a3e89c 207 SUPERFAMILY SSF47616 84 202 2.46E-35 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS16355 55563c4c5c5d4da1ebe23706e9a3e89c 207 Pfam PF00043 Glutathione S-transferase, C-terminal domain 124 192 2.3E-12 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS16355 55563c4c5c5d4da1ebe23706e9a3e89c 207 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 75 8.9E-15 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS16355 55563c4c5c5d4da1ebe23706e9a3e89c 207 Gene3D G3DSA:1.20.1050.10 97 203 5.6E-30 T 29-03-2018 CVS48_RS16355 55563c4c5c5d4da1ebe23706e9a3e89c 207 SUPERFAMILY SSF52833 2 79 5.04E-23 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 PRINTS PR00143 Citrate synthase signature 387 401 2.6E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 PRINTS PR00143 Citrate synthase signature 367 383 2.6E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 PRINTS PR00143 Citrate synthase signature 169 182 2.6E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 PRINTS PR00143 Citrate synthase signature 223 238 2.6E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 PRINTS PR00143 Citrate synthase signature 245 273 2.6E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 PRINTS PR00143 Citrate synthase signature 303 323 2.6E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 Gene3D G3DSA:1.10.580.10 346 412 1.5E-8 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 Gene3D G3DSA:1.10.580.10 33 302 7.6E-87 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 PIRSF PIRSF001369 41 436 1.1E-160 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 18 430 3.6E-234 T 29-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 SUPERFAMILY SSF48256 10 436 3.93E-160 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 Pfam PF00285 Citrate synthase, C-terminal domain 50 419 5.5E-128 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27885 d713fd0a51d43d004cc7e552a3a25e94 436 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CVS48_RS26585 df378e21abf1be27a16d08137451a2fe 152 SUPERFAMILY SSF47175 27 149 6.33E-41 T 29-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 CVS48_RS26585 df378e21abf1be27a16d08137451a2fe 152 PIRSF PIRSF000027 7 151 2.9E-46 T 29-03-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 CVS48_RS26585 df378e21abf1be27a16d08137451a2fe 152 Pfam PF01322 Cytochrome C' 32 149 1.8E-36 T 29-03-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 CVS48_RS26585 df378e21abf1be27a16d08137451a2fe 152 Gene3D G3DSA:1.20.120.10 26 152 9.5E-40 T 29-03-2018 CVS48_RS26585 df378e21abf1be27a16d08137451a2fe 152 PRINTS PR00608 Class II cytochrome C signature 115 138 1.1E-8 T 29-03-2018 IPR015984 Cytochrome c prime, subgroup CVS48_RS26585 df378e21abf1be27a16d08137451a2fe 152 PRINTS PR00608 Class II cytochrome C signature 138 149 1.1E-8 T 29-03-2018 IPR015984 Cytochrome c prime, subgroup CVS48_RS12075 ebe46ead3d81bb534f5eb29c8e0f4454 217 Gene3D G3DSA:1.10.10.10 155 209 7.7E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12075 ebe46ead3d81bb534f5eb29c8e0f4454 217 SUPERFAMILY SSF46785 146 211 2.61E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12075 ebe46ead3d81bb534f5eb29c8e0f4454 217 SUPERFAMILY SSF55811 3 141 1.16E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS12075 ebe46ead3d81bb534f5eb29c8e0f4454 217 Gene3D G3DSA:3.90.79.10 2 154 3.1E-29 T 29-03-2018 CVS48_RS28690 e75fb64fd05f1008f43d5b7986587db1 418 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 418 2.9E-185 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28690 e75fb64fd05f1008f43d5b7986587db1 418 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 29-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28690 e75fb64fd05f1008f43d5b7986587db1 418 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 418 49.982 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28690 e75fb64fd05f1008f43d5b7986587db1 418 Gene3D G3DSA:1.10.645.10 233 410 2.4E-47 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28690 e75fb64fd05f1008f43d5b7986587db1 418 Gene3D G3DSA:1.10.645.10 2 232 1.1E-62 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28690 e75fb64fd05f1008f43d5b7986587db1 418 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 418 1.2E-123 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28690 e75fb64fd05f1008f43d5b7986587db1 418 SUPERFAMILY SSF56762 194 418 3.66E-138 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28690 e75fb64fd05f1008f43d5b7986587db1 418 SUPERFAMILY SSF56762 16 167 3.66E-138 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS17655 5dad104cbf3b751043ab374beed4a4fc 470 Gene3D G3DSA:3.40.630.10 15 208 2.0E-26 T 29-03-2018 CVS48_RS17655 5dad104cbf3b751043ab374beed4a4fc 470 Pfam PF07687 Peptidase dimerisation domain 203 353 2.8E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS17655 5dad104cbf3b751043ab374beed4a4fc 470 SUPERFAMILY SSF53187 369 455 2.58E-46 T 29-03-2018 CVS48_RS17655 5dad104cbf3b751043ab374beed4a4fc 470 SUPERFAMILY SSF53187 19 205 2.58E-46 T 29-03-2018 CVS48_RS17655 5dad104cbf3b751043ab374beed4a4fc 470 Gene3D G3DSA:3.30.70.360 209 367 1.3E-28 T 29-03-2018 CVS48_RS17655 5dad104cbf3b751043ab374beed4a4fc 470 Pfam PF01546 Peptidase family M20/M25/M40 89 450 2.5E-21 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS24990 89b89149918f0abcfd39a3dee0201300 195 Gene3D G3DSA:2.60.40.1090 29 195 1.3E-20 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CVS48_RS24990 89b89149918f0abcfd39a3dee0201300 195 SUPERFAMILY SSF49401 30 195 5.97E-14 T 29-03-2018 IPR008966 Adhesion domain CVS48_RS03395 bdd0b52556d09ed2a7557672d726051c 328 Pfam PF12833 Helix-turn-helix domain 246 325 5.4E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS03395 bdd0b52556d09ed2a7557672d726051c 328 SMART SM00342 240 324 1.3E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS03395 bdd0b52556d09ed2a7557672d726051c 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 277 320 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS03395 bdd0b52556d09ed2a7557672d726051c 328 Pfam PF14525 AraC-binding-like domain 27 205 4.4E-46 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CVS48_RS03395 bdd0b52556d09ed2a7557672d726051c 328 Gene3D G3DSA:1.10.10.60 219 278 1.7E-10 T 29-03-2018 CVS48_RS03395 bdd0b52556d09ed2a7557672d726051c 328 SUPERFAMILY SSF46689 276 326 2.15E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS03395 bdd0b52556d09ed2a7557672d726051c 328 SUPERFAMILY SSF46689 224 270 6.99E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS03395 bdd0b52556d09ed2a7557672d726051c 328 Gene3D G3DSA:1.10.10.60 279 327 1.2E-6 T 29-03-2018 CVS48_RS25920 da87b41714504ec33f156384625a966a 285 Gene3D G3DSA:1.10.3720.10 24 283 7.1E-34 T 29-03-2018 CVS48_RS25920 da87b41714504ec33f156384625a966a 285 SUPERFAMILY SSF161098 89 272 4.19E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS25920 da87b41714504ec33f156384625a966a 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 280 3.7E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19260 7cabbeca59d17376c9c740d19c48ee7e 493 Pfam PF07969 Amidohydrolase family 51 468 1.0E-33 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS19260 7cabbeca59d17376c9c740d19c48ee7e 493 Gene3D G3DSA:2.30.40.10 7 73 1.8E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS19260 7cabbeca59d17376c9c740d19c48ee7e 493 SUPERFAMILY SSF51556 62 424 6.35E-83 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS19260 7cabbeca59d17376c9c740d19c48ee7e 493 SUPERFAMILY SSF51338 9 61 4.07E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS19260 7cabbeca59d17376c9c740d19c48ee7e 493 SUPERFAMILY SSF51338 424 477 4.07E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS19260 7cabbeca59d17376c9c740d19c48ee7e 493 Gene3D G3DSA:2.30.40.10 407 483 6.2E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS19260 7cabbeca59d17376c9c740d19c48ee7e 493 Gene3D G3DSA:3.20.20.140 74 406 4.6E-71 T 29-03-2018 CVS48_RS21595 85b4122d11aa04f994f10aa3aa143e08 285 Pfam PF08722 TnsA endonuclease N terminal 73 164 5.8E-21 T 29-03-2018 IPR014833 TnsA endonuclease, N-terminal CVS48_RS21595 85b4122d11aa04f994f10aa3aa143e08 285 Pfam PF08721 TnsA endonuclease C terminal 169 254 2.1E-7 T 29-03-2018 IPR014832 TnsA endonuclease C-terminal CVS48_RS21595 85b4122d11aa04f994f10aa3aa143e08 285 Gene3D G3DSA:1.10.10.10 173 265 6.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21595 85b4122d11aa04f994f10aa3aa143e08 285 Gene3D G3DSA:3.40.1350.10 5 169 2.1E-39 T 29-03-2018 CVS48_RS21595 85b4122d11aa04f994f10aa3aa143e08 285 SUPERFAMILY SSF52980 6 168 1.72E-47 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 Gene3D G3DSA:1.10.10.10 7 79 9.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 SMART SM00345 18 77 4.7E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 Pfam PF07702 UTRA domain 132 233 2.1E-11 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 7.0E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 7.0E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 SUPERFAMILY SSF64288 65 242 8.48E-23 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 SMART SM00866 102 238 7.1E-8 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 Gene3D G3DSA:3.40.1410.10 104 247 2.3E-17 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 SUPERFAMILY SSF46785 10 79 5.96E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15855 fba640a1f6d14bff2c004a0ca5a76c58 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 1.2E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 Pfam PF01590 GAF domain 72 206 7.2E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 Gene3D G3DSA:3.40.50.300 342 508 3.2E-22 T 29-03-2018 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 590 607 2.1E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 607 627 2.1E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 Pfam PF00158 Sigma-54 interaction domain 339 502 8.6E-58 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 SUPERFAMILY SSF55781 66 206 1.06E-5 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 Gene3D G3DSA:1.10.10.60 570 628 6.1E-11 T 29-03-2018 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 SMART SM00382 356 499 2.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 546 555 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 Pfam PF02954 Bacterial regulatory protein, Fis family 588 624 1.9E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 Gene3D G3DSA:3.30.450.40 28 218 1.2E-11 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 360 373 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 Gene3D G3DSA:3.30.450.20 223 341 0.0014 T 29-03-2018 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 SUPERFAMILY SSF52540 338 578 6.5E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 SUPERFAMILY SSF46689 587 626 3.54E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 Gene3D G3DSA:1.10.8.60 509 569 9.0E-18 T 29-03-2018 CVS48_RS10160 9aca5f1410034dfffc517fdd650a500b 632 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 422 437 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CVS48_RS06615 d3a50d771c9eed4100d09ecada337960 667 Pfam PF05140 ResB-like family 1 655 1.4E-154 T 29-03-2018 IPR007816 ResB-like domain CVS48_RS03575 23cdf1c8bac2d9d50efb94ed23517a8e 147 SMART SM00421 12 69 8.1E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS03575 23cdf1c8bac2d9d50efb94ed23517a8e 147 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 15 29 1.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS03575 23cdf1c8bac2d9d50efb94ed23517a8e 147 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 45 57 1.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS03575 23cdf1c8bac2d9d50efb94ed23517a8e 147 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 29 45 1.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS03575 23cdf1c8bac2d9d50efb94ed23517a8e 147 SUPERFAMILY SSF46894 5 73 1.16E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS03575 23cdf1c8bac2d9d50efb94ed23517a8e 147 Pfam PF00196 Bacterial regulatory proteins, luxR family 14 67 4.9E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS03575 23cdf1c8bac2d9d50efb94ed23517a8e 147 Gene3D G3DSA:1.10.10.10 2 77 1.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22975 8354b94a2b364805b43a0ab81d59bfac 325 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 303 1.5E-15 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS22975 8354b94a2b364805b43a0ab81d59bfac 325 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS22975 8354b94a2b364805b43a0ab81d59bfac 325 SUPERFAMILY SSF52540 8 257 9.65E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22975 8354b94a2b364805b43a0ab81d59bfac 325 Pfam PF00005 ABC transporter 28 186 5.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22975 8354b94a2b364805b43a0ab81d59bfac 325 Gene3D G3DSA:3.40.50.300 5 324 3.8E-79 T 29-03-2018 CVS48_RS22975 8354b94a2b364805b43a0ab81d59bfac 325 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 322 1.1E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS22975 8354b94a2b364805b43a0ab81d59bfac 325 SMART SM00382 37 236 3.4E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03050 d23fc62531efa0b560251387e35740f1 454 Gene3D G3DSA:3.30.2290.10 3 236 1.3E-59 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CVS48_RS03050 d23fc62531efa0b560251387e35740f1 454 SUPERFAMILY SSF111283 17 454 1.31E-124 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CVS48_RS03050 d23fc62531efa0b560251387e35740f1 454 Pfam PF01523 Putative modulator of DNA gyrase 38 327 1.5E-62 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 518 935 3.5E-123 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 SUPERFAMILY SSF63418 511 585 8.63E-19 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 30 508 1.5E-142 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 486 936 31.629 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 SUPERFAMILY SSF53244 344 508 9.16E-42 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Pfam PF02875 Mur ligase family, glutamate ligase domain 805 888 1.6E-14 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Pfam PF02875 Mur ligase family, glutamate ligase domain 345 441 1.9E-18 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 SUPERFAMILY SSF53623 590 803 3.4E-53 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Pfam PF08245 Mur ligase middle domain 595 784 2.1E-40 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Pfam PF08245 Mur ligase middle domain 118 323 1.4E-48 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 SUPERFAMILY SSF53623 109 340 2.75E-69 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Gene3D G3DSA:3.90.190.20 360 515 6.5E-46 T 29-03-2018 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 508 32.646 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 SUPERFAMILY SSF63418 28 107 1.96E-18 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Gene3D G3DSA:3.40.1190.10 109 348 1.2E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Pfam PF01225 Mur ligase family, catalytic domain 30 106 4.8E-12 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Pfam PF01225 Mur ligase family, catalytic domain 513 560 2.6E-5 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Gene3D G3DSA:3.40.1390.10 11 108 1.2E-18 T 29-03-2018 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Gene3D G3DSA:3.90.190.20 805 948 6.3E-42 T 29-03-2018 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 SUPERFAMILY SSF53244 805 935 5.63E-35 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Gene3D G3DSA:3.40.1190.10 580 801 4.7E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS02490 f85c4116920fc7f67efdafc68b7820ab 952 Gene3D G3DSA:3.40.1390.10 516 579 9.5E-21 T 29-03-2018 CVS48_RS20445 3793d8f3463e9f659418e00a6e128327 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 124 1.3E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS20445 3793d8f3463e9f659418e00a6e128327 135 Gene3D G3DSA:3.10.180.10 5 134 1.1E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS20445 3793d8f3463e9f659418e00a6e128327 135 SUPERFAMILY SSF54593 6 129 3.62E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS05595 f953418b192264e6807dc1d97ca3d703 802 Gene3D G3DSA:2.30.30.60 576 623 1.5E-5 T 29-03-2018 CVS48_RS05595 f953418b192264e6807dc1d97ca3d703 802 Gene3D G3DSA:3.30.70.100 628 721 2.9E-11 T 29-03-2018 CVS48_RS05595 f953418b192264e6807dc1d97ca3d703 802 SUPERFAMILY SSF50182 559 619 1.41E-9 T 29-03-2018 IPR010920 LSM domain CVS48_RS05595 f953418b192264e6807dc1d97ca3d703 802 SUPERFAMILY SSF82689 632 727 5.62E-14 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CVS48_RS05595 f953418b192264e6807dc1d97ca3d703 802 SUPERFAMILY SSF82861 473 557 5.89E-14 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CVS48_RS05595 f953418b192264e6807dc1d97ca3d703 802 Pfam PF00924 Mechanosensitive ion channel 517 715 2.6E-31 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CVS48_RS12845 968f8e25db78d527630bb02cb52a57af 204 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 1 194 3.3E-61 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CVS48_RS12845 968f8e25db78d527630bb02cb52a57af 204 Gene3D G3DSA:3.90.550.10 1 201 2.7E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS12845 968f8e25db78d527630bb02cb52a57af 204 SUPERFAMILY SSF53448 1 193 2.17E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS12845 968f8e25db78d527630bb02cb52a57af 204 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 196 23.08 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CVS48_RS12845 968f8e25db78d527630bb02cb52a57af 204 Pfam PF12804 MobA-like NTP transferase domain 1 163 1.3E-28 T 29-03-2018 IPR025877 MobA-like NTP transferase CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 Pfam PF13380 CoA binding domain 14 141 1.9E-20 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 162 297 4.3E-38 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 Gene3D G3DSA:3.40.50.261 301 466 8.6E-27 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 Pfam PF13549 ATP-grasp domain 479 694 1.2E-62 T 29-03-2018 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 Gene3D G3DSA:3.40.50.261 143 299 5.9E-30 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 SUPERFAMILY SSF52210 138 300 1.44E-30 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 SUPERFAMILY SSF51735 8 137 2.69E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 Gene3D G3DSA:3.30.470.20 562 706 6.5E-26 T 29-03-2018 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 SMART SM00881 10 107 4.0E-30 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 SUPERFAMILY SSF56059 479 702 1.59E-40 T 29-03-2018 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 Gene3D G3DSA:3.30.1490.20 501 561 5.7E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 SUPERFAMILY SSF52210 306 459 1.22E-25 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS11190 c1fdae6f0d864b49d58c7f686e4db618 709 Gene3D G3DSA:3.40.50.720 10 142 2.7E-33 T 29-03-2018 CVS48_RS09500 ea5ff1533b2154790b74f9372413c9fc 475 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 472 4.5E-48 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS09500 ea5ff1533b2154790b74f9372413c9fc 475 Gene3D G3DSA:1.10.45.10 434 473 1.2E-11 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CVS48_RS09500 ea5ff1533b2154790b74f9372413c9fc 475 Pfam PF01565 FAD binding domain 43 180 4.9E-36 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS09500 ea5ff1533b2154790b74f9372413c9fc 475 Gene3D G3DSA:3.30.465.10 98 240 7.7E-39 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS09500 ea5ff1533b2154790b74f9372413c9fc 475 Gene3D G3DSA:3.30.43.10 5 97 2.0E-23 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS09500 ea5ff1533b2154790b74f9372413c9fc 475 SUPERFAMILY SSF56176 7 221 4.35E-71 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS09500 ea5ff1533b2154790b74f9372413c9fc 475 SUPERFAMILY SSF55103 195 474 5.56E-51 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS09420 571d4c3701ebc8deed7f7c82bafdb18e 358 Gene3D G3DSA:2.60.120.10 54 358 1.2E-38 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS09420 571d4c3701ebc8deed7f7c82bafdb18e 358 Pfam PF07883 Cupin domain 102 173 4.1E-24 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS09420 571d4c3701ebc8deed7f7c82bafdb18e 358 TIGRFAM TIGR02272 gentisate_1_2: gentisate 1,2-dioxygenase 18 356 1.9E-173 T 29-03-2018 IPR011960 Gentisate 1,2-dioxygenase CVS48_RS09420 571d4c3701ebc8deed7f7c82bafdb18e 358 SUPERFAMILY SSF51182 18 356 5.41E-114 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS27230 01e9da8fd8e8b2dced2199610f4bb678 325 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 10 292 38.199 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CVS48_RS27230 01e9da8fd8e8b2dced2199610f4bb678 325 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 12 290 3.2E-100 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CVS48_RS27230 01e9da8fd8e8b2dced2199610f4bb678 325 Pfam PF02401 LytB protein 12 288 1.0E-92 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CVS48_RS03525 38b9bb371e64a9c7752b9fda75a145e9 416 SUPERFAMILY SSF54373 272 362 5.89E-11 T 29-03-2018 CVS48_RS03525 38b9bb371e64a9c7752b9fda75a145e9 416 Gene3D G3DSA:3.50.50.60 1 416 4.1E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS03525 38b9bb371e64a9c7752b9fda75a145e9 416 Pfam PF01266 FAD dependent oxidoreductase 2 400 5.0E-63 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS03525 38b9bb371e64a9c7752b9fda75a145e9 416 SUPERFAMILY SSF51905 1 54 1.14E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS03525 38b9bb371e64a9c7752b9fda75a145e9 416 SUPERFAMILY SSF51905 107 272 1.14E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS03525 38b9bb371e64a9c7752b9fda75a145e9 416 SUPERFAMILY SSF51905 362 415 1.14E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS11840 2d63905c25000f53ab5b335ca705f632 379 SUPERFAMILY SSF55073 229 378 3.3E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS11840 2d63905c25000f53ab5b335ca705f632 379 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 225 378 9.7E-43 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS11840 2d63905c25000f53ab5b335ca705f632 379 Pfam PF00990 Diguanylate cyclase, GGDEF domain 227 376 2.3E-40 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS11840 2d63905c25000f53ab5b335ca705f632 379 Gene3D G3DSA:3.30.70.270 209 379 2.6E-52 T 29-03-2018 CVS48_RS11840 2d63905c25000f53ab5b335ca705f632 379 SMART SM00267 213 379 3.2E-47 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS18935 534f83ed14d677e5839620c879840a86 208 Gene3D G3DSA:3.40.50.360 1 207 1.5E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS18935 534f83ed14d677e5839620c879840a86 208 SUPERFAMILY SSF52218 1 195 3.97E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS18935 534f83ed14d677e5839620c879840a86 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 203 23.35 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CVS48_RS18935 534f83ed14d677e5839620c879840a86 208 Pfam PF02525 Flavodoxin-like fold 1 196 6.2E-38 T 29-03-2018 IPR003680 Flavodoxin-like fold CVS48_RS23265 35d5cea398950e79a0e936004d9ebd72 505 SUPERFAMILY SSF56954 77 492 4.84E-118 T 29-03-2018 CVS48_RS23265 35d5cea398950e79a0e936004d9ebd72 505 SUPERFAMILY SSF56954 3 34 4.84E-118 T 29-03-2018 CVS48_RS23265 35d5cea398950e79a0e936004d9ebd72 505 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 489 3.6E-123 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS23265 35d5cea398950e79a0e936004d9ebd72 505 Pfam PF02321 Outer membrane efflux protein 306 487 9.1E-30 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS23265 35d5cea398950e79a0e936004d9ebd72 505 Pfam PF02321 Outer membrane efflux protein 86 278 2.9E-22 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS23265 35d5cea398950e79a0e936004d9ebd72 505 Gene3D G3DSA:1.20.1600.10 22 495 1.2E-108 T 29-03-2018 CVS48_RS26670 8ea42903a190e6c7e3c354386e342d4d 127 Pfam PF00816 H-NS histone family 12 118 5.3E-23 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 CVS48_RS26670 8ea42903a190e6c7e3c354386e342d4d 127 SUPERFAMILY SSF81273 84 126 6.28E-11 T 29-03-2018 CVS48_RS26670 8ea42903a190e6c7e3c354386e342d4d 127 SMART SM00528 81 125 7.7E-20 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CVS48_RS26670 8ea42903a190e6c7e3c354386e342d4d 127 Gene3D G3DSA:4.10.430.10 87 125 8.8E-17 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 Gene3D G3DSA:1.20.1640.10 274 500 6.3E-46 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 Gene3D G3DSA:1.20.1640.10 811 1027 2.3E-39 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82714 723 807 8.5E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82693 566 669 6.28E-26 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 Pfam PF00873 AcrB/AcrD/AcrF family 1 1025 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 Gene3D G3DSA:3.30.70.1430 38 140 1.3E-25 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1033 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82693 672 721 1.8E-25 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82693 808 856 1.8E-25 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 Gene3D G3DSA:3.30.70.1440 672 768 4.5E-15 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 3.6E-103 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 3.6E-103 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 3.6E-103 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 3.6E-103 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 3.6E-103 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 3.6E-103 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 3.6E-103 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 3.6E-103 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 3.6E-103 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 Gene3D G3DSA:3.30.2090.10 180 273 2.5E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82714 182 272 4.32E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82693 135 182 3.5E-23 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82693 274 329 3.5E-23 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 Gene3D G3DSA:3.30.70.1430 568 668 1.1E-19 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82866 831 1024 9.42E-44 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82866 296 497 7.98E-49 T 29-03-2018 CVS48_RS23270 f2ecf99235e1eee380f14c1573717ea0 1076 SUPERFAMILY SSF82693 38 128 2.09E-25 T 29-03-2018 CVS48_RS08615 09b094104227a1967e2f7f61b820379f 251 SUPERFAMILY SSF52096 1 237 1.03E-62 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS08615 09b094104227a1967e2f7f61b820379f 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 236 4.7E-41 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS08615 09b094104227a1967e2f7f61b820379f 251 Gene3D G3DSA:3.90.226.10 1 244 4.2E-59 T 29-03-2018 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 211 252 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 SUPERFAMILY SSF51182 14 184 7.41E-18 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 240 256 6.6E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 240 6.6E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 SUPERFAMILY SSF46689 211 257 3.67E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 SMART SM00342 174 256 8.4E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 Gene3D G3DSA:1.10.10.60 212 259 5.9E-10 T 29-03-2018 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 Gene3D G3DSA:1.10.10.60 155 211 1.9E-13 T 29-03-2018 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 Pfam PF12833 Helix-turn-helix domain 180 257 1.1E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 Pfam PF02311 AraC-like ligand binding domain 22 140 1.2E-9 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS11710 948215582ce21139dc8ee7e4aa65411e 259 Gene3D G3DSA:2.60.120.10 2 96 5.8E-10 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS24735 a5217cbd6f015b3d5d29ad5cd0c396b9 329 Pfam PF13387 Domain of unknown function (DUF4105) 119 268 2.2E-41 T 29-03-2018 IPR025178 Domain of unknown function DUF4105 CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 282 5.5E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 551 586 5.8E-9 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 Pfam PF00005 ABC transporter 36 199 8.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 Pfam PF00005 ABC transporter 349 498 1.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 Gene3D G3DSA:3.40.50.300 12 291 8.0E-68 T 29-03-2018 CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 Gene3D G3DSA:3.40.50.300 318 604 9.0E-73 T 29-03-2018 CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 SUPERFAMILY SSF52540 321 571 3.43E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 SUPERFAMILY SSF52540 16 271 3.51E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 SMART SM00382 44 249 3.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 SMART SM00382 357 549 1.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28050 8d0d015be9b02dd82b306238bc3b50c5 628 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 549 599 1.1E-10 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 584 1069 6.0E-47 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 Pfam PF03797 Autotransporter beta-domain 797 1048 1.5E-55 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 SUPERFAMILY SSF51126 264 660 3.11E-19 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 SUPERFAMILY SSF103515 790 1069 4.97E-61 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 SUPERFAMILY SSF103515 734 761 4.97E-61 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 SMART SM00869 794 1059 5.5E-45 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 Gene3D G3DSA:2.160.20.20 355 639 2.3E-5 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 Gene3D G3DSA:2.40.128.130 725 1069 1.7E-56 T 29-03-2018 CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 309 352 1.2E-10 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 148 195 9.1E-12 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 407 454 1.5E-10 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS11310 76ef7c9778b89bea7f32c3e9cddd6d05 1069 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 257 303 1.4E-7 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 386 2.7E-99 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 Gene3D G3DSA:3.50.50.60 1 361 3.1E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 293 306 - T 29-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 SUPERFAMILY SSF51905 1 169 4.63E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 SUPERFAMILY SSF51905 275 385 4.63E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.5E-18 T 29-03-2018 CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.5E-18 T 29-03-2018 CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.5E-18 T 29-03-2018 CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.5E-18 T 29-03-2018 CVS48_RS04210 8d0afeb71ece198c9232f05ea3e7fe25 389 Pfam PF01494 FAD binding domain 4 338 5.8E-20 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS01535 259ab258d8bbcfc9abf7ff7c2fb03c32 333 Pfam PF00005 ABC transporter 24 182 1.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS01535 259ab258d8bbcfc9abf7ff7c2fb03c32 333 Gene3D G3DSA:3.40.50.300 1 331 5.7E-77 T 29-03-2018 CVS48_RS01535 259ab258d8bbcfc9abf7ff7c2fb03c32 333 SUPERFAMILY SSF52540 4 253 1.09E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01535 259ab258d8bbcfc9abf7ff7c2fb03c32 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 298 2.6E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS01535 259ab258d8bbcfc9abf7ff7c2fb03c32 333 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS01535 259ab258d8bbcfc9abf7ff7c2fb03c32 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 307 1.8E-21 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS01535 259ab258d8bbcfc9abf7ff7c2fb03c32 333 SMART SM00382 33 232 2.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16520 19041f1c5324da0fe9099747e73edbbe 251 SUPERFAMILY SSF52540 4 237 2.51E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16520 19041f1c5324da0fe9099747e73edbbe 251 SMART SM00382 30 215 8.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16520 19041f1c5324da0fe9099747e73edbbe 251 Pfam PF00005 ABC transporter 22 165 5.8E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS16520 19041f1c5324da0fe9099747e73edbbe 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 237 1.1E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS16520 19041f1c5324da0fe9099747e73edbbe 251 Gene3D G3DSA:3.40.50.300 1 246 5.3E-57 T 29-03-2018 CVS48_RS04000 5a1c1e77c29c4147eff4d146aff3d8b1 537 Gene3D G3DSA:3.90.76.10 31 176 1.2E-30 T 29-03-2018 CVS48_RS04000 5a1c1e77c29c4147eff4d146aff3d8b1 537 SUPERFAMILY SSF53850 18 518 8.51E-127 T 29-03-2018 CVS48_RS04000 5a1c1e77c29c4147eff4d146aff3d8b1 537 Gene3D G3DSA:3.40.190.10 187 310 2.3E-33 T 29-03-2018 CVS48_RS04000 5a1c1e77c29c4147eff4d146aff3d8b1 537 Gene3D G3DSA:3.10.105.10 311 508 7.0E-51 T 29-03-2018 CVS48_RS04000 5a1c1e77c29c4147eff4d146aff3d8b1 537 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 64 448 3.9E-89 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS04000 5a1c1e77c29c4147eff4d146aff3d8b1 537 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 70 91 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CVS48_RS04000 5a1c1e77c29c4147eff4d146aff3d8b1 537 PIRSF PIRSF002741 11 527 8.1E-93 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS00150 b67b59e04507c6f4d24c81313172e070 327 SUPERFAMILY SSF53850 116 280 1.56E-9 T 29-03-2018 CVS48_RS00150 b67b59e04507c6f4d24c81313172e070 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 5.5E-75 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS00150 b67b59e04507c6f4d24c81313172e070 327 Gene3D G3DSA:3.40.190.10 128 238 2.1E-10 T 29-03-2018 CVS48_RS00150 b67b59e04507c6f4d24c81313172e070 327 PIRSF PIRSF017082 1 326 1.8E-69 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 Gene3D G3DSA:3.30.450.20 190 330 0.01 T 29-03-2018 CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 SUPERFAMILY SSF55874 475 619 6.81E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 SMART SM00387 525 643 7.9E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 Gene3D G3DSA:3.30.450.20 82 189 7.2E-20 T 29-03-2018 CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 SMART SM00388 415 483 1.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 Gene3D G3DSA:3.30.565.10 483 651 3.0E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 SUPERFAMILY SSF103190 123 214 1.91E-15 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 PIRSF PIRSF036431 15 650 2.2E-183 T 29-03-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 526 639 3.9E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 Pfam PF00512 His Kinase A (phospho-acceptor) domain 416 480 1.4E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 593 611 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 578 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 592 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 Gene3D G3DSA:1.10.287.130 403 479 2.3E-12 T 29-03-2018 CVS48_RS14310 7f743a57d539888d8966299f2cf2ec8d 659 SUPERFAMILY SSF47384 400 479 4.32E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS14040 af8ce284f17b3ab0fa7fd5fbf897471a 249 Pfam PF10099 Anti-sigma-K factor rskA 64 242 7.3E-22 T 29-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 SUPERFAMILY SSF52467 187 361 7.46E-63 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 5.6E-60 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 330 1.8E-44 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 542 5.1E-48 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 SUPERFAMILY SSF52518 371 566 3.4E-66 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 Gene3D G3DSA:3.40.50.970 354 564 1.1E-48 T 29-03-2018 CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 SUPERFAMILY SSF52518 2 175 1.18E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 565 1.1E-246 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 Gene3D G3DSA:3.40.50.970 1 192 5.6E-64 T 29-03-2018 CVS48_RS00075 383a87e6cefe8723b3f23cb72dcb0053 571 Gene3D G3DSA:3.40.50.1220 193 353 3.1E-50 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS02135 46bfa746a9a5ad08ee5248e501266223 259 Pfam PF09850 Type VI secretion system protein DotU 30 226 1.7E-57 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU CVS48_RS02135 46bfa746a9a5ad08ee5248e501266223 259 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 29 233 4.4E-59 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 Gene3D G3DSA:1.10.10.10 1 83 2.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 Gene3D G3DSA:3.40.190.10 178 268 3.2E-27 T 29-03-2018 CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.6E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.6E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.6E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 SUPERFAMILY SSF46785 1 84 1.09E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.9E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 SUPERFAMILY SSF53850 89 293 5.07E-38 T 29-03-2018 CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 Gene3D G3DSA:3.40.190.10 88 177 2.1E-22 T 29-03-2018 CVS48_RS09530 faa32eeb3dfb8d449c4155acd6fadd34 298 Pfam PF03466 LysR substrate binding domain 87 293 4.4E-43 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 SUPERFAMILY SSF52029 184 376 1.36E-82 T 29-03-2018 IPR027409 GroEL-like apical domain CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 SUPERFAMILY SSF48592 406 521 9.99E-76 T 29-03-2018 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 SUPERFAMILY SSF48592 7 134 9.99E-76 T 29-03-2018 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 1.1E-97 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 Gene3D G3DSA:1.10.560.10 1 185 5.0E-41 T 29-03-2018 IPR027413 GroEL-like equatorial domain CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 Hamap MF_00600 60 kDa chaperonin [groL]. 2 544 41.472 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 Gene3D G3DSA:1.10.560.10 374 516 9.2E-26 T 29-03-2018 IPR027413 GroEL-like equatorial domain CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 SUPERFAMILY SSF54849 137 202 8.93E-25 T 29-03-2018 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 Gene3D G3DSA:3.50.7.10 186 373 6.6E-96 T 29-03-2018 IPR027409 GroEL-like apical domain CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 3.5E-254 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 PRINTS PR00298 60kDa chaperonin signature 27 53 5.5E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 PRINTS PR00298 60kDa chaperonin signature 83 110 5.5E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 PRINTS PR00298 60kDa chaperonin signature 268 291 5.5E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 PRINTS PR00298 60kDa chaperonin signature 350 375 5.5E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 PRINTS PR00298 60kDa chaperonin signature 398 419 5.5E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CVS48_RS11160 a98f538dec4b424967dbb338626d2e1f 546 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 SUPERFAMILY SSF56601 448 755 1.62E-116 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 SUPERFAMILY SSF56601 230 252 1.62E-116 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 SUPERFAMILY SSF56601 285 336 1.62E-116 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 Gene3D G3DSA:3.40.710.10 265 753 3.8E-114 T 29-03-2018 CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 Pfam PF17092 Penicillin-binding protein OB-like domain 339 450 1.0E-15 T 29-03-2018 IPR031376 Penicillin-binding protein, OB-like domain CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 Pfam PF00905 Penicillin binding protein transpeptidase domain 454 709 1.4E-36 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 Pfam PF00912 Transglycosylase 76 249 5.3E-64 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 SUPERFAMILY SSF53955 61 270 6.47E-76 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 84 738 5.0E-172 T 29-03-2018 CVS48_RS15355 3fadd243a897a9605da552dcaef0fb50 886 Gene3D G3DSA:1.10.3810.10 67 264 3.6E-78 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 Gene3D G3DSA:3.40.190.10 169 258 1.6E-26 T 29-03-2018 CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 SUPERFAMILY SSF46785 2 81 8.88E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 SUPERFAMILY SSF53850 83 290 8.07E-42 T 29-03-2018 CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 56 8.7E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 44 5.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 12 23 5.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 33 5.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 Pfam PF03466 LysR substrate binding domain 82 286 1.4E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 Gene3D G3DSA:3.40.190.10 85 168 2.8E-12 T 29-03-2018 CVS48_RS11740 27be934fd89a106fc1cc1d44135718d4 303 Gene3D G3DSA:1.10.10.10 1 84 2.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18180 80217f4b12ab4b5cee453476d9d2b4d0 97 Pfam PF07235 Protein of unknown function (DUF1427) 2 80 1.1E-36 T 29-03-2018 IPR009872 Protein of unknown function DUF1427 CVS48_RS18180 80217f4b12ab4b5cee453476d9d2b4d0 97 TIGRFAM TIGR03510 XapX: XapX domain 4 49 8.2E-19 T 29-03-2018 IPR020017 XapX domain CVS48_RS10105 0a44d57ef6ff2d6bedfa6458d63def8c 381 SUPERFAMILY SSF54637 275 380 1.1E-12 T 29-03-2018 IPR029069 HotDog domain CVS48_RS10105 0a44d57ef6ff2d6bedfa6458d63def8c 381 SUPERFAMILY SSF54637 211 244 1.1E-12 T 29-03-2018 IPR029069 HotDog domain CVS48_RS10105 0a44d57ef6ff2d6bedfa6458d63def8c 381 Gene3D G3DSA:3.10.129.10 19 181 2.2E-23 T 29-03-2018 CVS48_RS10105 0a44d57ef6ff2d6bedfa6458d63def8c 381 Gene3D G3DSA:3.10.129.10 210 381 6.5E-25 T 29-03-2018 CVS48_RS10105 0a44d57ef6ff2d6bedfa6458d63def8c 381 Pfam PF13452 N-terminal half of MaoC dehydratase 30 158 2.1E-17 T 29-03-2018 CVS48_RS10105 0a44d57ef6ff2d6bedfa6458d63def8c 381 SUPERFAMILY SSF54637 29 181 8.85E-21 T 29-03-2018 IPR029069 HotDog domain CVS48_RS03025 a165aae5aeee4e497acf88d2cdeb357e 262 Gene3D G3DSA:3.40.50.300 1 262 4.7E-66 T 29-03-2018 CVS48_RS03025 a165aae5aeee4e497acf88d2cdeb357e 262 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS03025 a165aae5aeee4e497acf88d2cdeb357e 262 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 248 5.6E-11 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS03025 a165aae5aeee4e497acf88d2cdeb357e 262 SMART SM00382 26 225 6.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03025 a165aae5aeee4e497acf88d2cdeb357e 262 Pfam PF00005 ABC transporter 17 178 1.0E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS03025 a165aae5aeee4e497acf88d2cdeb357e 262 SUPERFAMILY SSF52540 2 249 1.02E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04935 e9b0198e3653c4e100b853a978bf26bb 344 Pfam PF02628 Cytochrome oxidase assembly protein 10 320 4.0E-80 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 Gene3D G3DSA:3.40.640.10 177 303 8.1E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 PIRSF PIRSF000521 4 130 3.6E-6 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 PIRSF PIRSF000521 177 417 5.1E-32 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 PIRSF PIRSF000521 123 158 0.13 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 SUPERFAMILY SSF53383 8 414 9.41E-102 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 420 1.5E-143 T 29-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 4 415 7.1E-198 T 29-03-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 Pfam PF00202 Aminotransferase class-III 20 412 8.8E-78 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 Gene3D G3DSA:3.90.1150.10 4 165 8.3E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS14520 d5357448833c93af1ce5262e85ce1903 435 Gene3D G3DSA:3.90.1150.10 304 421 8.2E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS00240 ae35e44d76e186adfebd512a77ea75c3 496 Gene3D G3DSA:2.30.40.10 396 462 2.9E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS00240 ae35e44d76e186adfebd512a77ea75c3 496 Gene3D G3DSA:2.30.40.10 1 65 4.8E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS00240 ae35e44d76e186adfebd512a77ea75c3 496 Gene3D G3DSA:3.20.20.140 66 395 4.0E-76 T 29-03-2018 CVS48_RS00240 ae35e44d76e186adfebd512a77ea75c3 496 SUPERFAMILY SSF51556 56 414 4.9E-84 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS00240 ae35e44d76e186adfebd512a77ea75c3 496 Pfam PF07969 Amidohydrolase family 44 458 1.5E-44 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS00240 ae35e44d76e186adfebd512a77ea75c3 496 SUPERFAMILY SSF51338 1 55 2.16E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS00240 ae35e44d76e186adfebd512a77ea75c3 496 SUPERFAMILY SSF51338 414 473 2.16E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25620 97b682b057a7e744996c3449c1756782 360 PIRSF PIRSF018266 28 360 3.5E-86 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS25620 97b682b057a7e744996c3449c1756782 360 Pfam PF04773 FecR protein 151 242 4.9E-23 T 29-03-2018 IPR006860 FecR protein CVS48_RS25620 97b682b057a7e744996c3449c1756782 360 Pfam PF16220 Domain of unknown function (DUF4880) 36 73 3.0E-14 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS25620 97b682b057a7e744996c3449c1756782 360 Pfam PF16344 Domain of unknown function (DUF4974) 259 334 1.8E-7 T 29-03-2018 IPR032508 Protein FecR, C-terminal CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 27.786 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 SUPERFAMILY SSF110324 2 81 3.1E-32 T 29-03-2018 CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 Pfam PF01016 Ribosomal L27 protein 2 81 7.5E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 73 2.0E-14 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 6.3E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.8E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.8E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.8E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS08080 096ae8ffe9d502d3912b985137c43382 86 Gene3D G3DSA:2.40.50.100 20 85 1.9E-27 T 29-03-2018 CVS48_RS05720 333c6dea7a61424e125285b78a018a31 875 Pfam PF14345 GDYXXLXY protein 718 867 1.0E-38 T 29-03-2018 IPR025833 GDYXXLXY protein CVS48_RS05720 333c6dea7a61424e125285b78a018a31 875 Pfam PF14351 Domain of unknown function (DUF4401) 350 679 7.2E-67 T 29-03-2018 IPR025513 Domain of unknown function DUF4401 CVS48_RS05720 333c6dea7a61424e125285b78a018a31 875 Pfam PF09925 Predicted membrane protein (DUF2157) 13 137 9.7E-25 T 29-03-2018 IPR018677 Domain of unknown function DUF2157 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 292 402 1.0E-10 T 29-03-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 Pfam PF00174 Oxidoreductase molybdopterin binding domain 107 269 6.3E-39 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 235 248 6.5E-21 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 163 178 6.5E-21 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 218 234 6.5E-21 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 332 344 6.5E-21 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 377 389 6.5E-21 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 251 264 6.5E-21 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 84 100 6.5E-21 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 SUPERFAMILY SSF56524 65 327 3.01E-53 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 Gene3D G3DSA:3.90.420.10 34 288 6.7E-48 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 SUPERFAMILY SSF81296 296 406 1.12E-24 T 29-03-2018 IPR014756 Immunoglobulin E-set CVS48_RS11285 80d524fa60b6ff56cdf56bdceded1709 412 Gene3D G3DSA:2.60.40.650 295 411 3.4E-27 T 29-03-2018 CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 SMART SM00490 480 566 3.1E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 Gene3D G3DSA:3.40.50.300 436 609 5.1E-32 T 29-03-2018 CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 Gene3D G3DSA:3.40.50.300 28 435 1.0E-29 T 29-03-2018 CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 Pfam PF04851 Type III restriction enzyme, res subunit 59 158 2.0E-8 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 Gene3D G3DSA:4.10.860.10 610 685 7.7E-11 T 29-03-2018 IPR001943 UVR domain GO:0005515 CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 Pfam PF12344 Ultra-violet resistance protein B 572 614 2.1E-18 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 SUPERFAMILY SSF52540 25 435 7.71E-134 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 Hamap MF_00204 UvrABC system protein B [uvrB]. 24 680 42.422 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 26 678 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 Pfam PF00271 Helicase conserved C-terminal domain 463 564 1.4E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 SUPERFAMILY SSF52540 58 103 6.46E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 SUPERFAMILY SSF52540 479 604 6.46E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 SMART SM00487 30 452 3.0E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS21945 5736a0460c848d4475b9a03e2f00ca40 687 SUPERFAMILY SSF46600 642 680 3.27E-8 T 29-03-2018 IPR001943 UVR domain GO:0005515 CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 Pfam PF03466 LysR substrate binding domain 87 288 4.0E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 Gene3D G3DSA:3.40.190.10 92 177 2.5E-19 T 29-03-2018 CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 SUPERFAMILY SSF53850 89 284 2.59E-32 T 29-03-2018 CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 Gene3D G3DSA:3.40.190.10 178 266 1.5E-16 T 29-03-2018 CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 Gene3D G3DSA:1.10.10.10 1 91 1.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.1E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22920 a9c2cf3dee8a9705162f2f7d77fe7686 295 SUPERFAMILY SSF46785 1 111 2.28E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04050 00ca29c64600160ccda0304a1709c2dd 283 SUPERFAMILY SSF56235 2 275 5.83E-29 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS04050 00ca29c64600160ccda0304a1709c2dd 283 Gene3D G3DSA:3.60.20.10 1 274 1.1E-39 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS04050 00ca29c64600160ccda0304a1709c2dd 283 Pfam PF13230 Glutamine amidotransferases class-II 28 181 5.7E-13 T 29-03-2018 IPR026869 Putative glutamine amidotransferase type 2 CVS48_RS17350 8cdc4421ca8bf10180bbe714bb4009ae 269 Gene3D G3DSA:3.90.640.20 174 268 3.0E-18 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CVS48_RS17350 8cdc4421ca8bf10180bbe714bb4009ae 269 Pfam PF11738 Protein of unknown function (DUF3298) 192 255 1.3E-11 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CVS48_RS17350 8cdc4421ca8bf10180bbe714bb4009ae 269 Gene3D G3DSA:3.30.565.40 42 173 2.8E-13 T 29-03-2018 CVS48_RS04575 fc46e1b2f9449cc734ff146412dea3d5 536 Gene3D G3DSA:3.40.50.980 175 350 1.1E-9 T 29-03-2018 CVS48_RS04575 fc46e1b2f9449cc734ff146412dea3d5 536 Gene3D G3DSA:3.40.50.980 33 166 7.4E-9 T 29-03-2018 CVS48_RS04575 fc46e1b2f9449cc734ff146412dea3d5 536 Pfam PF00501 AMP-binding enzyme 187 411 1.0E-11 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS04575 fc46e1b2f9449cc734ff146412dea3d5 536 SUPERFAMILY SSF56801 46 415 4.06E-31 T 29-03-2018 CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 Gene3D G3DSA:3.40.190.10 88 177 7.8E-24 T 29-03-2018 CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.6E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.6E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.6E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 Pfam PF03466 LysR substrate binding domain 87 288 2.7E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 Gene3D G3DSA:3.40.190.10 178 269 1.6E-28 T 29-03-2018 CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 Gene3D G3DSA:1.10.10.10 1 82 3.1E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 SUPERFAMILY SSF46785 1 86 6.22E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 SUPERFAMILY SSF53850 88 296 1.52E-38 T 29-03-2018 CVS48_RS19115 da20b06280982ac2cc98c7664e182ebb 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.0E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 Pfam PF13458 Periplasmic binding protein 30 369 6.7E-62 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 SUPERFAMILY SSF53822 30 372 4.37E-93 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 Gene3D G3DSA:3.40.50.2300 20 180 1.7E-39 T 29-03-2018 CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 260 278 3.5E-35 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 335 350 3.5E-35 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 72 90 3.5E-35 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 93 103 3.5E-35 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 53 69 3.5E-35 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 283 296 3.5E-35 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 31 47 3.5E-35 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19325 d94b512d75c452ffd7532063fa0fd09a 375 Gene3D G3DSA:3.40.50.2300 181 356 1.9E-24 T 29-03-2018 CVS48_RS27365 6e56ab8439f2fd17329f915fca85b504 492 Pfam PF04055 Radical SAM superfamily 130 308 6.1E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS27365 6e56ab8439f2fd17329f915fca85b504 492 SUPERFAMILY SSF102114 108 340 1.57E-12 T 29-03-2018 CVS48_RS27365 6e56ab8439f2fd17329f915fca85b504 492 Gene3D G3DSA:3.20.20.70 97 392 1.3E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS27365 6e56ab8439f2fd17329f915fca85b504 492 SMART SM00729 126 351 3.2E-5 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CVS48_RS27685 2c5c50a3a83cc8add0ff3f57f40164f3 254 Gene3D G3DSA:3.60.140.10 3 253 1.2E-89 T 29-03-2018 CVS48_RS27685 2c5c50a3a83cc8add0ff3f57f40164f3 254 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 24 250 1.7E-75 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CVS48_RS27685 2c5c50a3a83cc8add0ff3f57f40164f3 254 SUPERFAMILY SSF64438 11 251 1.74E-76 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CVS48_RS27685 2c5c50a3a83cc8add0ff3f57f40164f3 254 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 32 251 2.4E-49 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CVS48_RS11030 c64c097cd02c3a66edf9c60b1f136243 177 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 16 147 2.4E-37 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS11030 c64c097cd02c3a66edf9c60b1f136243 177 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 151 26.416 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS11030 c64c097cd02c3a66edf9c60b1f136243 177 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 148 1.8E-47 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS11030 c64c097cd02c3a66edf9c60b1f136243 177 SUPERFAMILY SSF52121 7 151 1.2E-49 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS11030 c64c097cd02c3a66edf9c60b1f136243 177 Gene3D G3DSA:3.40.50.960 7 152 2.5E-51 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS11805 a047e5af22b48552ef11f5eeded7366f 511 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 10 295 1.1E-50 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CVS48_RS11805 a047e5af22b48552ef11f5eeded7366f 511 Pfam PF05683 Fumarase C-terminus 323 503 5.5E-71 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CVS48_RS11805 a047e5af22b48552ef11f5eeded7366f 511 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 341 500 2.5E-43 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CVS48_RS11805 a047e5af22b48552ef11f5eeded7366f 511 PIRSF PIRSF001394 1 511 1.7E-166 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CVS48_RS11805 a047e5af22b48552ef11f5eeded7366f 511 Pfam PF05681 Fumarate hydratase (Fumerase) 12 298 1.0E-83 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CVS48_RS11805 a047e5af22b48552ef11f5eeded7366f 511 SUPERFAMILY SSF117457 332 502 1.03E-57 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CVS48_RS11805 a047e5af22b48552ef11f5eeded7366f 511 Gene3D G3DSA:3.20.130.10 330 503 8.2E-62 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 SUPERFAMILY SSF52833 518 629 2.31E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 220 420 1.6E-17 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 Gene3D G3DSA:2.60.40.1250 44 170 4.0E-37 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 Gene3D G3DSA:3.40.30.10 546 632 1.9E-10 T 29-03-2018 CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 Gene3D G3DSA:3.40.30.10 519 545 0.0027 T 29-03-2018 CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 26 631 34.246 T 29-03-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 SUPERFAMILY SSF74863 47 166 1.23E-31 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 Pfam PF13899 Thioredoxin-like 530 604 1.3E-9 T 29-03-2018 CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 Pfam PF11412 Disulphide bond corrector protein DsbC 49 165 1.5E-30 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CVS48_RS06590 18d85ef2e231d4e4d5c06b20d10d1a22 633 ProSitePatterns PS00194 Thioredoxin family active site. 539 557 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 SUPERFAMILY SSF103515 1563 1868 6.93E-39 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Pfam PF13018 Extended Signal Peptide of Type V secretion system 46 67 2.3E-8 T 29-03-2018 IPR024973 ESPR domain CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 SUPERFAMILY SSF51126 989 1322 1.13E-16 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1012 1043 4.7E-11 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1272 1303 6.8E-9 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1363 1394 5.9E-12 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 720 752 1.9E-8 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 630 660 1.5E-9 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 SUPERFAMILY SSF51126 668 844 3.45E-9 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 SUPERFAMILY SSF51126 1315 1543 3.14E-19 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Gene3D G3DSA:2.40.128.130 1555 1868 4.4E-45 T 29-03-2018 CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Gene3D G3DSA:3.30.1390.40 631 649 0.0082 T 29-03-2018 CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Gene3D G3DSA:3.30.1390.40 1013 1031 0.0082 T 29-03-2018 CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Gene3D G3DSA:2.160.20.20 1211 1550 1.1E-25 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1439 1868 2.0E-53 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 SUPERFAMILY SSF51126 333 680 2.23E-6 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 SMART SM00869 1594 1853 1.6E-33 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Pfam PF12951 Passenger-associated-transport-repeat 544 571 9.3E-4 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Pfam PF12951 Passenger-associated-transport-repeat 1363 1391 1.9E-9 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Pfam PF12951 Passenger-associated-transport-repeat 631 660 1.3E-10 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Pfam PF12951 Passenger-associated-transport-repeat 721 751 3.0E-7 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Pfam PF12951 Passenger-associated-transport-repeat 1273 1299 2.6E-7 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Pfam PF12951 Passenger-associated-transport-repeat 1176 1204 0.045 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS17500 43bf227bed16ff370b307be729cfa1d8 1868 Pfam PF12951 Passenger-associated-transport-repeat 1013 1041 3.6E-9 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS04510 f3fb370c263b5c7f195ee3d002b246da 348 SUPERFAMILY SSF52768 64 343 8.64E-87 T 29-03-2018 CVS48_RS04510 f3fb370c263b5c7f195ee3d002b246da 348 PIRSF PIRSF036979 49 346 1.3E-96 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS04510 f3fb370c263b5c7f195ee3d002b246da 348 ProSitePatterns PS01053 Arginase family signature. 270 291 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CVS48_RS04510 f3fb370c263b5c7f195ee3d002b246da 348 TIGRFAM TIGR01230 agmatinase: agmatinase 65 339 6.6E-60 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CVS48_RS04510 f3fb370c263b5c7f195ee3d002b246da 348 Gene3D G3DSA:3.40.800.10 20 347 2.1E-93 T 29-03-2018 CVS48_RS04510 f3fb370c263b5c7f195ee3d002b246da 348 Pfam PF00491 Arginase family 71 338 1.8E-85 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS02395 8341b0febdf264305740b7243b17915b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02395 8341b0febdf264305740b7243b17915b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02395 8341b0febdf264305740b7243b17915b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02395 8341b0febdf264305740b7243b17915b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02395 8341b0febdf264305740b7243b17915b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02395 8341b0febdf264305740b7243b17915b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02395 8341b0febdf264305740b7243b17915b 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 1.2E-33 T 29-03-2018 CVS48_RS02395 8341b0febdf264305740b7243b17915b 260 Gene3D G3DSA:3.40.50.720 5 256 1.6E-49 T 29-03-2018 CVS48_RS02395 8341b0febdf264305740b7243b17915b 260 SUPERFAMILY SSF51735 7 254 4.54E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09135 44bc48b8c80e8226bd66a0af515c8d78 182 Pfam PF06073 Bacterial protein of unknown function (DUF934) 70 176 1.7E-32 T 29-03-2018 IPR008318 Uncharacterised conserved protein UCP030820 CVS48_RS09135 44bc48b8c80e8226bd66a0af515c8d78 182 PIRSF PIRSF030820 16 182 3.6E-44 T 29-03-2018 IPR008318 Uncharacterised conserved protein UCP030820 CVS48_RS02510 ac07ecbf226063b5417faf8a1301b9e5 142 SUPERFAMILY SSF89447 2 128 1.94E-37 T 29-03-2018 CVS48_RS02510 ac07ecbf226063b5417faf8a1301b9e5 142 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 117 5.0E-59 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CVS48_RS02510 ac07ecbf226063b5417faf8a1301b9e5 142 Pfam PF02381 MraZ protein, putative antitoxin-like 73 120 1.5E-10 T 29-03-2018 IPR020603 MraZ domain CVS48_RS02510 ac07ecbf226063b5417faf8a1301b9e5 142 Pfam PF02381 MraZ protein, putative antitoxin-like 2 69 2.6E-13 T 29-03-2018 IPR020603 MraZ domain CVS48_RS02510 ac07ecbf226063b5417faf8a1301b9e5 142 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 142 48.045 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CVS48_RS02510 ac07ecbf226063b5417faf8a1301b9e5 142 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 129 4.0E-35 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CVS48_RS02510 ac07ecbf226063b5417faf8a1301b9e5 142 Gene3D G3DSA:2.10.260.10 3 47 6.1E-5 T 29-03-2018 CVS48_RS02510 ac07ecbf226063b5417faf8a1301b9e5 142 Gene3D G3DSA:2.10.260.10 78 120 0.0085 T 29-03-2018 CVS48_RS11175 9b7b62178c57883d24dbf85d3cfd87b6 376 Gene3D G3DSA:3.40.50.10540 1 376 9.1E-115 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS11175 9b7b62178c57883d24dbf85d3cfd87b6 376 Pfam PF02515 CoA-transferase family III 5 352 2.4E-79 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS11175 9b7b62178c57883d24dbf85d3cfd87b6 376 SUPERFAMILY SSF89796 3 375 3.4E-115 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS03285 c738983210b7834af15ae576a0e15113 275 Gene3D G3DSA:3.40.190.10 1 158 1.2E-29 T 29-03-2018 CVS48_RS03285 c738983210b7834af15ae576a0e15113 275 SMART SM00062 35 259 1.1E-49 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS03285 c738983210b7834af15ae576a0e15113 275 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 59 72 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CVS48_RS03285 c738983210b7834af15ae576a0e15113 275 SUPERFAMILY SSF53850 7 258 1.23E-57 T 29-03-2018 CVS48_RS03285 c738983210b7834af15ae576a0e15113 275 Gene3D G3DSA:3.40.190.10 159 269 2.5E-14 T 29-03-2018 CVS48_RS03285 c738983210b7834af15ae576a0e15113 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 257 6.9E-54 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS18510 5e2347b396e752f9d36a609a6d070bfd 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 1.3E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS18510 5e2347b396e752f9d36a609a6d070bfd 328 PIRSF PIRSF017082 1 328 1.1E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS18510 5e2347b396e752f9d36a609a6d070bfd 328 SUPERFAMILY SSF53850 117 290 4.34E-12 T 29-03-2018 CVS48_RS18510 5e2347b396e752f9d36a609a6d070bfd 328 Gene3D G3DSA:3.40.190.10 127 263 2.5E-10 T 29-03-2018 CVS48_RS16850 3d37eeea66819161f196d800cab14ce3 97 Gene3D G3DSA:1.10.287.1160 62 90 9.1E-10 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CVS48_RS16850 3d37eeea66819161f196d800cab14ce3 97 SUPERFAMILY SSF101498 24 91 2.48E-12 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CVS48_RS16850 3d37eeea66819161f196d800cab14ce3 97 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 2 92 6.3E-17 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CVS48_RS16850 3d37eeea66819161f196d800cab14ce3 97 Pfam PF04316 Anti-sigma-28 factor, FlgM 40 89 8.0E-13 T 29-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 Gene3D G3DSA:3.40.50.880 1 188 1.7E-58 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.2E-6 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.2E-6 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.1E-13 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 2.1E-13 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 2.1E-13 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 SUPERFAMILY SSF52317 2 187 2.38E-56 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 Pfam PF00117 Glutamine amidotransferase class-I 4 185 1.6E-54 T 29-03-2018 IPR017926 Glutamine amidotransferase CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00097 Anthranilate synthase component II signature 119 131 3.1E-33 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00097 Anthranilate synthase component II signature 164 177 3.1E-33 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00097 Anthranilate synthase component II signature 99 107 3.1E-33 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 3.1E-33 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00097 Anthranilate synthase component II signature 47 56 3.1E-33 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 PRINTS PR00097 Anthranilate synthase component II signature 74 85 3.1E-33 T 29-03-2018 CVS48_RS04240 f0370fe2c288bffd7552259d65992570 188 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 2.9E-78 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 Gene3D G3DSA:3.30.870.10 111 286 2.6E-33 T 29-03-2018 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 SMART SM00155 398 425 9.7E-6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 SMART SM00155 220 247 12.0 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 SUPERFAMILY SSF56024 109 316 5.23E-52 T 29-03-2018 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 Pfam PF13396 Phospholipase_D-nuclease N-terminal 27 63 2.7E-5 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 Pfam PF13091 PLD-like domain 328 449 8.1E-25 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 Pfam PF13091 PLD-like domain 137 280 8.2E-17 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 PIRSF PIRSF000850 370 447 6.4E-4 T 29-03-2018 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 PIRSF PIRSF000850 118 190 0.032 T 29-03-2018 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 PIRSF PIRSF000850 314 378 0.055 T 29-03-2018 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 16 485 8.7E-88 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 SUPERFAMILY SSF56024 272 469 7.18E-47 T 29-03-2018 CVS48_RS24895 c42b93661fbc92f04651062ddd7ed425 485 Gene3D G3DSA:3.30.870.10 313 476 1.6E-29 T 29-03-2018 CVS48_RS16820 4582751f4c1ef9273331534950b333c4 211 PIRSF PIRSF002884 1 211 5.1E-86 T 29-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 CVS48_RS16820 4582751f4c1ef9273331534950b333c4 211 Gene3D G3DSA:1.10.287.500 35 167 1.5E-21 T 29-03-2018 CVS48_RS16820 4582751f4c1ef9273331534950b333c4 211 SUPERFAMILY SSF75708 13 210 2.48E-63 T 29-03-2018 CVS48_RS16820 4582751f4c1ef9273331534950b333c4 211 Pfam PF04344 Chemotaxis phosphatase, CheZ 15 211 7.5E-77 T 29-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 CVS48_RS16820 4582751f4c1ef9273331534950b333c4 211 Gene3D G3DSA:1.20.5.590 4 33 1.2E-12 T 29-03-2018 CVS48_RS21335 203ebdc251e745e8887bb5ad6312c3e7 552 PIRSF PIRSF000137 1 552 5.8E-144 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS21335 203ebdc251e745e8887bb5ad6312c3e7 552 Pfam PF05199 GMC oxidoreductase 395 536 4.7E-35 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS21335 203ebdc251e745e8887bb5ad6312c3e7 552 SUPERFAMILY SSF51905 3 296 3.45E-89 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21335 203ebdc251e745e8887bb5ad6312c3e7 552 SUPERFAMILY SSF51905 483 544 3.45E-89 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21335 203ebdc251e745e8887bb5ad6312c3e7 552 Gene3D G3DSA:4.10.450.10 35 103 2.4E-28 T 29-03-2018 CVS48_RS21335 203ebdc251e745e8887bb5ad6312c3e7 552 Pfam PF00732 GMC oxidoreductase 4 303 9.1E-86 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS21335 203ebdc251e745e8887bb5ad6312c3e7 552 Gene3D G3DSA:3.30.560.10 104 499 7.1E-100 T 29-03-2018 CVS48_RS21335 203ebdc251e745e8887bb5ad6312c3e7 552 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 262 276 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS21335 203ebdc251e745e8887bb5ad6312c3e7 552 SUPERFAMILY SSF54373 298 484 3.24E-55 T 29-03-2018 CVS48_RS20860 3b1d389e56761ce15a83e96398779273 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 7.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20860 3b1d389e56761ce15a83e96398779273 199 Pfam PF16925 Bacterial transcriptional repressor C-terminal 80 162 1.5E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS20860 3b1d389e56761ce15a83e96398779273 199 SUPERFAMILY SSF48498 79 192 7.23E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS20860 3b1d389e56761ce15a83e96398779273 199 Gene3D G3DSA:1.10.10.60 1 67 2.9E-16 T 29-03-2018 CVS48_RS20860 3b1d389e56761ce15a83e96398779273 199 Gene3D G3DSA:1.10.357.10 68 199 1.7E-27 T 29-03-2018 CVS48_RS20860 3b1d389e56761ce15a83e96398779273 199 SUPERFAMILY SSF46689 2 82 1.44E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS20360 8d40cd60588d651a20652cbaac438e92 464 Gene3D G3DSA:3.30.70.360 207 366 1.2E-28 T 29-03-2018 CVS48_RS20360 8d40cd60588d651a20652cbaac438e92 464 Pfam PF07687 Peptidase dimerisation domain 201 352 2.1E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS20360 8d40cd60588d651a20652cbaac438e92 464 Pfam PF01546 Peptidase family M20/M25/M40 90 447 5.8E-20 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS20360 8d40cd60588d651a20652cbaac438e92 464 Gene3D G3DSA:3.40.630.10 10 206 4.1E-25 T 29-03-2018 CVS48_RS20360 8d40cd60588d651a20652cbaac438e92 464 SUPERFAMILY SSF53187 369 454 6.29E-45 T 29-03-2018 CVS48_RS20360 8d40cd60588d651a20652cbaac438e92 464 SUPERFAMILY SSF53187 17 203 6.29E-45 T 29-03-2018 CVS48_RS20835 afb2e112e8fbd0f4362520e92ec9cc87 582 Pfam PF00664 ABC transporter transmembrane region 25 296 3.8E-19 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS20835 afb2e112e8fbd0f4362520e92ec9cc87 582 Gene3D G3DSA:1.20.1560.10 6 324 4.1E-32 T 29-03-2018 CVS48_RS20835 afb2e112e8fbd0f4362520e92ec9cc87 582 Pfam PF00005 ABC transporter 357 505 3.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS20835 afb2e112e8fbd0f4362520e92ec9cc87 582 SMART SM00382 366 566 3.5E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS20835 afb2e112e8fbd0f4362520e92ec9cc87 582 Gene3D G3DSA:3.40.50.300 338 581 1.2E-57 T 29-03-2018 CVS48_RS20835 afb2e112e8fbd0f4362520e92ec9cc87 582 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS20835 afb2e112e8fbd0f4362520e92ec9cc87 582 SUPERFAMILY SSF90123 481 490 1.1E-39 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS20835 afb2e112e8fbd0f4362520e92ec9cc87 582 SUPERFAMILY SSF90123 19 307 1.1E-39 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS20835 afb2e112e8fbd0f4362520e92ec9cc87 582 SUPERFAMILY SSF52540 336 572 1.46E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13235 10399a5a7763f5c88d35598662e3f405 87 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 7.9E-22 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CVS48_RS13235 10399a5a7763f5c88d35598662e3f405 87 SUPERFAMILY SSF50249 1 71 1.69E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS13235 10399a5a7763f5c88d35598662e3f405 87 Gene3D G3DSA:2.40.50.140 1 72 8.7E-31 T 29-03-2018 CVS48_RS13235 10399a5a7763f5c88d35598662e3f405 87 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 25.682 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CVS48_RS13235 10399a5a7763f5c88d35598662e3f405 87 SMART SM00316 4 72 0.0031 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS13235 10399a5a7763f5c88d35598662e3f405 87 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 1.6E-29 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CVS48_RS23600 b15a3311a62cb09889cf72d4517c57f3 443 Gene3D G3DSA:3.40.50.300 146 418 3.1E-32 T 29-03-2018 CVS48_RS23600 b15a3311a62cb09889cf72d4517c57f3 443 Gene3D G3DSA:3.40.50.2300 11 140 6.0E-8 T 29-03-2018 CVS48_RS23600 b15a3311a62cb09889cf72d4517c57f3 443 SUPERFAMILY SSF52172 25 137 1.04E-7 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS23600 b15a3311a62cb09889cf72d4517c57f3 443 SUPERFAMILY SSF52540 208 415 6.38E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06385 cf0319242b07d95d40acf02736eff98d 233 ProSitePatterns PS00474 Ribosomal protein L3 signature. 119 142 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site CVS48_RS06385 cf0319242b07d95d40acf02736eff98d 233 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 18 222 1.6E-84 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06385 cf0319242b07d95d40acf02736eff98d 233 Pfam PF00297 Ribosomal protein L3 82 199 2.4E-19 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06385 cf0319242b07d95d40acf02736eff98d 233 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 16 225 38.575 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06385 cf0319242b07d95d40acf02736eff98d 233 Gene3D G3DSA:4.10.960.10 64 183 1.2E-29 T 29-03-2018 CVS48_RS06385 cf0319242b07d95d40acf02736eff98d 233 SUPERFAMILY SSF50447 12 230 3.09E-79 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS06855 1e9edc65019ff69ed355daa558fbb84f 285 Gene3D G3DSA:3.40.50.850 1 285 1.5E-36 T 29-03-2018 CVS48_RS06855 1e9edc65019ff69ed355daa558fbb84f 285 SUPERFAMILY SSF52499 6 83 9.03E-13 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS06855 1e9edc65019ff69ed355daa558fbb84f 285 SUPERFAMILY SSF52499 134 273 9.03E-13 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 3.1E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.1E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 3.1E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 1.1E-62 T 29-03-2018 CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 SUPERFAMILY SSF51735 6 247 1.3E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 Gene3D G3DSA:3.40.50.720 45 249 2.6E-58 T 29-03-2018 CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 Gene3D G3DSA:3.40.50.720 1 44 2.8E-10 T 29-03-2018 CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11770 f14eb36aee56c96e4bcdf38b6c02cb45 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 0.0013 T 29-03-2018 CVS48_RS24235 9c64491adb5c1a0aa46c0726546aede6 147 Gene3D G3DSA:3.30.1330.40 21 144 8.5E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS24235 9c64491adb5c1a0aa46c0726546aede6 147 Pfam PF01042 Endoribonuclease L-PSP 24 133 5.3E-24 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS24235 9c64491adb5c1a0aa46c0726546aede6 147 SUPERFAMILY SSF55298 24 138 2.36E-33 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS25090 cf4ba9b0b05b3073e8606a4f8b0e41f0 343 SUPERFAMILY SSF51735 154 253 5.64E-6 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25090 cf4ba9b0b05b3073e8606a4f8b0e41f0 343 Pfam PF13478 XdhC Rossmann domain 166 308 3.3E-39 T 29-03-2018 IPR027051 XdhC Rossmann domain CVS48_RS25090 cf4ba9b0b05b3073e8606a4f8b0e41f0 343 Gene3D G3DSA:3.40.50.720 155 326 1.5E-6 T 29-03-2018 CVS48_RS25090 cf4ba9b0b05b3073e8606a4f8b0e41f0 343 Pfam PF02625 XdhC and CoxI family 16 70 7.1E-21 T 29-03-2018 IPR003777 XdhC- CoxI CVS48_RS19295 e8dd9a59cbaa55fd359c944bdd74073d 184 Pfam PF02592 Putative vitamin uptake transporter 43 85 7.2E-10 T 29-03-2018 IPR003744 Queuosine precursor transporter CVS48_RS19295 e8dd9a59cbaa55fd359c944bdd74073d 184 Pfam PF02592 Putative vitamin uptake transporter 87 172 2.9E-19 T 29-03-2018 IPR003744 Queuosine precursor transporter CVS48_RS19295 e8dd9a59cbaa55fd359c944bdd74073d 184 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 86 164 2.2E-14 T 29-03-2018 IPR003744 Queuosine precursor transporter CVS48_RS19275 f49e4ce4912ca8461c75a8d246af3e13 255 Gene3D G3DSA:3.40.50.300 2 254 1.3E-57 T 29-03-2018 CVS48_RS19275 f49e4ce4912ca8461c75a8d246af3e13 255 SMART SM00382 30 231 1.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19275 f49e4ce4912ca8461c75a8d246af3e13 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 253 1.4E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS19275 f49e4ce4912ca8461c75a8d246af3e13 255 SUPERFAMILY SSF52540 5 253 7.21E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19275 f49e4ce4912ca8461c75a8d246af3e13 255 Pfam PF00005 ABC transporter 22 181 3.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 Gene3D G3DSA:3.90.230.10 1 260 5.0E-77 T 29-03-2018 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 Pfam PF00557 Metallopeptidase family M24 11 245 5.1E-49 T 29-03-2018 IPR000994 Peptidase M24 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 9.7E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 9.7E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 9.7E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 9.7E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 171 189 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 Hamap MF_01974 Methionine aminopeptidase [map]. 2 254 38.572 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 SUPERFAMILY SSF55920 3 255 1.7E-82 T 29-03-2018 IPR000994 Peptidase M24 CVS48_RS17115 94703a573194b1ade70612f31eeef332 273 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 253 5.0E-90 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS17895 8815567942df36b9be448fa2add97da9 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 239 7.8E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS17895 8815567942df36b9be448fa2add97da9 245 SUPERFAMILY SSF161098 32 224 7.46E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS17895 8815567942df36b9be448fa2add97da9 245 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 30 133 4.1E-16 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS17895 8815567942df36b9be448fa2add97da9 245 Gene3D G3DSA:1.10.3720.10 2 241 1.1E-35 T 29-03-2018 CVS48_RS15385 db8d87361cf024f801473acac66c4d3c 138 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 128 5.2E-15 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CVS48_RS15385 db8d87361cf024f801473acac66c4d3c 138 Pfam PF03061 Thioesterase superfamily 47 122 9.5E-16 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CVS48_RS15385 db8d87361cf024f801473acac66c4d3c 138 SUPERFAMILY SSF54637 4 134 7.31E-35 T 29-03-2018 IPR029069 HotDog domain CVS48_RS15385 db8d87361cf024f801473acac66c4d3c 138 Gene3D G3DSA:3.10.129.10 1 133 7.7E-35 T 29-03-2018 CVS48_RS26275 a2967c8600c3fc608dfb0ac0b56b6013 324 SUPERFAMILY SSF53850 155 271 4.49E-6 T 29-03-2018 CVS48_RS26275 a2967c8600c3fc608dfb0ac0b56b6013 324 SUPERFAMILY SSF53850 25 122 4.49E-6 T 29-03-2018 CVS48_RS26275 a2967c8600c3fc608dfb0ac0b56b6013 324 PIRSF PIRSF006470 1 324 2.5E-94 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS26275 a2967c8600c3fc608dfb0ac0b56b6013 324 Gene3D G3DSA:3.40.190.10 1 319 1.1E-4 T 29-03-2018 CVS48_RS26275 a2967c8600c3fc608dfb0ac0b56b6013 324 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 285 1.3E-65 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS26275 a2967c8600c3fc608dfb0ac0b56b6013 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 310 1.9E-83 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 Pfam PF00012 Hsp70 protein 275 390 5.2E-13 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 Pfam PF00012 Hsp70 protein 6 226 6.5E-14 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 Gene3D G3DSA:3.30.420.40 185 394 2.4E-32 T 29-03-2018 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 SUPERFAMILY SSF53067 175 243 1.64E-32 T 29-03-2018 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 SUPERFAMILY SSF53067 292 412 1.64E-32 T 29-03-2018 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 SUPERFAMILY SSF53067 5 172 5.55E-29 T 29-03-2018 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 370 384 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 180 193 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 PRINTS PR00301 70kDa heat shock protein signature 186 196 1.4E-6 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 PRINTS PR00301 70kDa heat shock protein signature 120 140 1.4E-6 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 PRINTS PR00301 70kDa heat shock protein signature 32 44 1.4E-6 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 PRINTS PR00301 70kDa heat shock protein signature 4 17 1.4E-6 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS22755 32ea4466ff70b428978e3d5de4d64e57 417 Gene3D G3DSA:3.30.420.40 2 184 1.4E-36 T 29-03-2018 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 SUPERFAMILY SSF55729 652 800 3.6E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 Gene3D G3DSA:3.40.50.261 276 440 2.1E-27 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 Pfam PF13549 ATP-grasp domain 499 612 4.1E-22 T 29-03-2018 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 SUPERFAMILY SSF52210 277 435 3.14E-27 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 Gene3D G3DSA:3.40.50.720 3 128 2.4E-5 T 29-03-2018 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 Gene3D G3DSA:3.40.50.261 129 275 4.8E-30 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 SUPERFAMILY SSF52210 127 271 1.44E-32 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 Pfam PF00583 Acetyltransferase (GNAT) family 722 794 1.3E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 Gene3D G3DSA:3.30.470.20 452 615 3.4E-26 T 29-03-2018 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 Gene3D G3DSA:3.40.630.30 642 813 1.3E-23 T 29-03-2018 CVS48_RS03085 904af628e42b7b43840d456910aa0a0d 813 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 271 1.1E-35 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CVS48_RS07665 2cc8ca2486643c123700ce18ba0ed1dd 191 SUPERFAMILY SSF48498 83 181 4.45E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS07665 2cc8ca2486643c123700ce18ba0ed1dd 191 SUPERFAMILY SSF46689 4 72 2.69E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS07665 2cc8ca2486643c123700ce18ba0ed1dd 191 Gene3D G3DSA:1.10.357.10 55 179 1.0E-11 T 29-03-2018 CVS48_RS07665 2cc8ca2486643c123700ce18ba0ed1dd 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 3.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS07665 2cc8ca2486643c123700ce18ba0ed1dd 191 Gene3D G3DSA:1.10.10.60 2 54 1.1E-11 T 29-03-2018 CVS48_RS23915 8c80874461823e18096e01647826778f 350 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 8 334 31.023 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CVS48_RS23915 8c80874461823e18096e01647826778f 350 Gene3D G3DSA:3.40.718.10 1 336 2.1E-111 T 29-03-2018 CVS48_RS23915 8c80874461823e18096e01647826778f 350 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 41 328 2.0E-91 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CVS48_RS23915 8c80874461823e18096e01647826778f 350 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 12 334 1.3E-97 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CVS48_RS23915 8c80874461823e18096e01647826778f 350 SUPERFAMILY SSF53659 10 336 2.06E-93 T 29-03-2018 CVS48_RS07300 a00a8ef00a93e3789f1ab6b36e09eca5 303 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 9 292 36.443 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CVS48_RS07300 a00a8ef00a93e3789f1ab6b36e09eca5 303 Pfam PF01678 Diaminopimelate epimerase 11 130 3.9E-32 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CVS48_RS07300 a00a8ef00a93e3789f1ab6b36e09eca5 303 Pfam PF01678 Diaminopimelate epimerase 173 283 2.4E-24 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CVS48_RS07300 a00a8ef00a93e3789f1ab6b36e09eca5 303 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 10 290 9.8E-82 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CVS48_RS07300 a00a8ef00a93e3789f1ab6b36e09eca5 303 Gene3D G3DSA:3.10.310.10 132 279 4.9E-45 T 29-03-2018 CVS48_RS07300 a00a8ef00a93e3789f1ab6b36e09eca5 303 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 72 86 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CVS48_RS07300 a00a8ef00a93e3789f1ab6b36e09eca5 303 SUPERFAMILY SSF54506 9 292 2.88E-47 T 29-03-2018 CVS48_RS07300 a00a8ef00a93e3789f1ab6b36e09eca5 303 Gene3D G3DSA:3.10.310.10 2 131 2.7E-48 T 29-03-2018 CVS48_RS21100 7cbb16c10de00c0630fbbe930a0d193e 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 4.3E-83 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21100 7cbb16c10de00c0630fbbe930a0d193e 322 PIRSF PIRSF017082 1 322 6.7E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21100 7cbb16c10de00c0630fbbe930a0d193e 322 Gene3D G3DSA:3.40.190.10 122 252 5.7E-9 T 29-03-2018 CVS48_RS21100 7cbb16c10de00c0630fbbe930a0d193e 322 SUPERFAMILY SSF53850 109 285 3.26E-15 T 29-03-2018 CVS48_RS06890 f49e8de7c305b04f06bf2866e01c3cbb 308 Pfam PF01040 UbiA prenyltransferase family 47 292 6.4E-52 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CVS48_RS06890 f49e8de7c305b04f06bf2866e01c3cbb 308 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 23 306 25.721 T 29-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 CVS48_RS06890 f49e8de7c305b04f06bf2866e01c3cbb 308 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 28 305 2.4E-91 T 29-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 CVS48_RS06890 f49e8de7c305b04f06bf2866e01c3cbb 308 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 85 107 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site CVS48_RS16580 b5832e24771271082b2953c994da2b85 296 Gene3D G3DSA:3.60.110.10 14 285 4.4E-79 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS16580 b5832e24771271082b2953c994da2b85 296 SUPERFAMILY SSF56317 16 285 6.28E-76 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS16580 b5832e24771271082b2953c994da2b85 296 Pfam PF00795 Carbon-nitrogen hydrolase 16 267 9.7E-53 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS28625 ca70c63ed74a5cea4e1efa6850498c31 285 SUPERFAMILY SSF56784 74 284 2.71E-48 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS28625 ca70c63ed74a5cea4e1efa6850498c31 285 Pfam PF12710 haloacid dehalogenase-like hydrolase 81 248 1.1E-18 T 29-03-2018 CVS48_RS28625 ca70c63ed74a5cea4e1efa6850498c31 285 Pfam PF13284 Domain of unknown function (DUF4072) 6 48 1.2E-11 T 29-03-2018 IPR025138 Domain of unknown function DUF4072 CVS48_RS28625 ca70c63ed74a5cea4e1efa6850498c31 285 Gene3D G3DSA:3.40.50.1000 137 283 1.0E-24 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS28625 ca70c63ed74a5cea4e1efa6850498c31 285 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 73 280 2.6E-69 T 29-03-2018 CVS48_RS28625 ca70c63ed74a5cea4e1efa6850498c31 285 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 79 248 2.1E-31 T 29-03-2018 CVS48_RS28625 ca70c63ed74a5cea4e1efa6850498c31 285 Gene3D G3DSA:1.10.150.210 89 136 5.5E-24 T 29-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CVS48_RS20850 ee90fa4c5d035535646157775e3d9c47 293 SUPERFAMILY SSF46785 1 111 1.22E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20850 ee90fa4c5d035535646157775e3d9c47 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.3E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20850 ee90fa4c5d035535646157775e3d9c47 293 SUPERFAMILY SSF53850 89 285 1.81E-29 T 29-03-2018 CVS48_RS20850 ee90fa4c5d035535646157775e3d9c47 293 Gene3D G3DSA:3.40.190.10 89 288 7.1E-16 T 29-03-2018 CVS48_RS20850 ee90fa4c5d035535646157775e3d9c47 293 Pfam PF03466 LysR substrate binding domain 87 277 1.4E-24 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20850 ee90fa4c5d035535646157775e3d9c47 293 Gene3D G3DSA:1.10.10.10 1 86 6.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22255 b8aef48bec0841401505358785a2325e 177 ProSitePatterns PS00855 Signal peptidases II signature. 116 128 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS22255 b8aef48bec0841401505358785a2325e 177 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 20 174 16.332 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS22255 b8aef48bec0841401505358785a2325e 177 TIGRFAM TIGR00077 lspA: signal peptidase II 28 175 5.6E-40 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS22255 b8aef48bec0841401505358785a2325e 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 66 74 2.7E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS22255 b8aef48bec0841401505358785a2325e 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 149 165 2.7E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS22255 b8aef48bec0841401505358785a2325e 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 113 128 2.7E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS22255 b8aef48bec0841401505358785a2325e 177 Pfam PF01252 Signal peptidase (SPase) II 29 168 1.8E-37 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS05555 297c113eaeac12fb6d229757cf04cc98 174 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 26 169 3.3E-22 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 CVS48_RS05555 297c113eaeac12fb6d229757cf04cc98 174 Gene3D G3DSA:1.20.1250.20 14 167 5.1E-4 T 29-03-2018 CVS48_RS04665 6a5f225e3a2c1234ca0bf84e4425442b 152 Gene3D G3DSA:1.20.1290.10 8 151 5.2E-30 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS04665 6a5f225e3a2c1234ca0bf84e4425442b 152 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 122 4.9E-16 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS04665 6a5f225e3a2c1234ca0bf84e4425442b 152 SUPERFAMILY SSF69118 5 127 2.16E-27 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS16480 ed2e941b188775f24cf1fbb40b6ece8a 151 Pfam PF13673 Acetyltransferase (GNAT) domain 35 136 7.7E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS16480 ed2e941b188775f24cf1fbb40b6ece8a 151 Gene3D G3DSA:3.40.630.30 1 142 4.3E-21 T 29-03-2018 CVS48_RS16480 ed2e941b188775f24cf1fbb40b6ece8a 151 SUPERFAMILY SSF55729 1 138 1.39E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS02735 5fb14c8080ced31c7160f744e16f23bb 154 SUPERFAMILY SSF52402 2 149 6.0E-36 T 29-03-2018 CVS48_RS02735 5fb14c8080ced31c7160f744e16f23bb 154 Gene3D G3DSA:3.40.50.620 1 154 6.1E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS02735 5fb14c8080ced31c7160f744e16f23bb 154 Pfam PF00582 Universal stress protein family 1 148 5.4E-31 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS02735 5fb14c8080ced31c7160f744e16f23bb 154 PRINTS PR01438 Universal stress protein signature 126 148 5.3E-18 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS02735 5fb14c8080ced31c7160f744e16f23bb 154 PRINTS PR01438 Universal stress protein signature 108 120 5.3E-18 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS02735 5fb14c8080ced31c7160f744e16f23bb 154 PRINTS PR01438 Universal stress protein signature 2 20 5.3E-18 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS24885 425d7d4da0ce89ab085a03b505af2e99 62 SUPERFAMILY SSF56349 2 55 2.27E-5 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 25 180 2.6E-65 T 29-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 143 159 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 106 179 6.3E-24 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 SUPERFAMILY SSF46557 26 100 3.14E-27 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 Hamap MF_00930 Transcription elongation factor GreB [greB]. 24 180 52.112 T 29-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 PIRSF PIRSF006092 24 180 1.3E-43 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 Gene3D G3DSA:3.10.50.30 100 180 4.0E-24 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 40 71 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 Gene3D G3DSA:1.10.287.180 26 98 2.6E-28 T 29-03-2018 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 Pfam PF03449 Transcription elongation factor, N-terminal 27 97 3.7E-25 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 SUPERFAMILY SSF54534 104 179 3.14E-20 T 29-03-2018 CVS48_RS21315 44d615b7b1aef41a2868318456242e17 180 Hamap MF_00105 Transcription elongation factor GreA [greA]. 25 178 27.118 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CVS48_RS13750 feea070651bc99a09ee376c57a859a3a 269 SUPERFAMILY SSF52540 7 232 4.48E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13750 feea070651bc99a09ee376c57a859a3a 269 Pfam PF00005 ABC transporter 29 167 6.0E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13750 feea070651bc99a09ee376c57a859a3a 269 Gene3D G3DSA:3.40.50.300 1 224 4.8E-57 T 29-03-2018 CVS48_RS13750 feea070651bc99a09ee376c57a859a3a 269 SMART SM00382 37 217 1.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13750 feea070651bc99a09ee376c57a859a3a 269 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 Pfam PF00376 MerR family regulatory protein 9 46 3.0E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 SMART SM00422 8 77 3.1E-29 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 SUPERFAMILY SSF46955 8 130 1.98E-28 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 Pfam PF09278 MerR, DNA binding 51 113 3.0E-18 T 29-03-2018 IPR015358 Transcription regulator MerR, DNA binding CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 ProSitePatterns PS00552 MerR-type HTH domain signature. 11 33 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 TIGRFAM TIGR02051 MerR: Hg(II)-responsive transcriptional regulator 9 132 7.8E-50 T 29-03-2018 IPR011794 Hg(II)-responsive transcriptional regulator GO:0003677|GO:0006355|GO:0045340|GO:0046689 CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 Gene3D G3DSA:1.10.1660.10 4 63 3.0E-19 T 29-03-2018 CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 Gene3D G3DSA:1.10.1660.10 64 134 1.3E-20 T 29-03-2018 CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 1.2E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 1.2E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS00865 d927175a4fe89f282a2d63d72abaa26a 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 1.2E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS16025 8fe8e5c4c507b92cb7140123a6214500 497 PIRSF PIRSF012702 1 497 1.8E-173 T 29-03-2018 IPR009197 Microcystin LR degradation protein MlrC CVS48_RS16025 8fe8e5c4c507b92cb7140123a6214500 497 Pfam PF07364 Metallopeptidase family M81 3 291 1.8E-102 T 29-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CVS48_RS16025 8fe8e5c4c507b92cb7140123a6214500 497 Gene3D G3DSA:3.20.20.120 78 369 0.0032 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS16025 8fe8e5c4c507b92cb7140123a6214500 497 Pfam PF07171 MlrC C-terminus 304 481 8.1E-57 T 29-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 222 446 4.7E-83 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 SUPERFAMILY SSF52777 223 446 4.89E-80 T 29-03-2018 CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 Pfam PF00364 Biotin-requiring enzyme 5 76 2.5E-15 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 Gene3D G3DSA:3.30.559.10 216 446 1.0E-90 T 29-03-2018 CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 SUPERFAMILY SSF47005 157 199 3.53E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 Pfam PF02817 e3 binding domain 162 196 3.3E-13 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 5 446 2.2E-143 T 29-03-2018 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 Gene3D G3DSA:2.40.50.100 5 77 4.4E-11 T 29-03-2018 CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 Gene3D G3DSA:4.10.320.10 152 215 6.8E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CVS48_RS09275 d07a02536ca25144d197762d7a78b920 446 SUPERFAMILY SSF51230 4 92 9.68E-22 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS21410 dc7bd1ea4d41b4e3a3bc7c479bd01f7c 353 Pfam PF00356 Bacterial regulatory proteins, lacI family 18 61 3.8E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS21410 dc7bd1ea4d41b4e3a3bc7c479bd01f7c 353 Gene3D G3DSA:3.40.50.2300 74 180 2.4E-12 T 29-03-2018 CVS48_RS21410 dc7bd1ea4d41b4e3a3bc7c479bd01f7c 353 Pfam PF13407 Periplasmic binding protein domain 122 320 1.3E-34 T 29-03-2018 IPR025997 Periplasmic binding protein CVS48_RS21410 dc7bd1ea4d41b4e3a3bc7c479bd01f7c 353 SUPERFAMILY SSF53822 76 334 3.93E-38 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS21410 dc7bd1ea4d41b4e3a3bc7c479bd01f7c 353 SUPERFAMILY SSF47413 15 63 5.16E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS21410 dc7bd1ea4d41b4e3a3bc7c479bd01f7c 353 Gene3D G3DSA:1.10.260.40 16 61 6.1E-11 T 29-03-2018 CVS48_RS21410 dc7bd1ea4d41b4e3a3bc7c479bd01f7c 353 ProSitePatterns PS00356 LacI-type HTH domain signature. 18 36 - T 29-03-2018 CVS48_RS21410 dc7bd1ea4d41b4e3a3bc7c479bd01f7c 353 Gene3D G3DSA:3.40.50.2300 181 352 5.4E-22 T 29-03-2018 CVS48_RS21410 dc7bd1ea4d41b4e3a3bc7c479bd01f7c 353 SMART SM00354 15 85 4.9E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CVS48_RS06610 0d4f633d86cdc0f077f272d60690bfcd 233 Pfam PF00034 Cytochrome c 166 225 3.7E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS06610 0d4f633d86cdc0f077f272d60690bfcd 233 Pfam PF00034 Cytochrome c 39 134 2.7E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS06610 0d4f633d86cdc0f077f272d60690bfcd 233 SUPERFAMILY SSF46626 147 231 5.24E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS06610 0d4f633d86cdc0f077f272d60690bfcd 233 SUPERFAMILY SSF46626 37 133 7.27E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS06610 0d4f633d86cdc0f077f272d60690bfcd 233 Gene3D G3DSA:1.10.760.10 19 134 8.8E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS06610 0d4f633d86cdc0f077f272d60690bfcd 233 Gene3D G3DSA:1.10.760.10 136 231 2.6E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS06610 0d4f633d86cdc0f077f272d60690bfcd 233 PIRSF PIRSF000005 2 233 4.5E-60 T 29-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 CVS48_RS28890 8e4375831ff1385b347b4083428bda2a 234 SUPERFAMILY SSF52172 1 173 4.27E-39 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS28890 8e4375831ff1385b347b4083428bda2a 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 1.7E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS28890 8e4375831ff1385b347b4083428bda2a 234 Gene3D G3DSA:3.40.50.2300 1 118 7.6E-34 T 29-03-2018 CVS48_RS28890 8e4375831ff1385b347b4083428bda2a 234 Gene3D G3DSA:1.10.10.10 119 224 2.4E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28890 8e4375831ff1385b347b4083428bda2a 234 Pfam PF00072 Response regulator receiver domain 3 111 5.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS28890 8e4375831ff1385b347b4083428bda2a 234 SMART SM00448 1 112 3.0E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS28890 8e4375831ff1385b347b4083428bda2a 234 SMART SM00862 145 218 5.3E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS02105 faedae41d58ed891b6a91bda64836e99 167 Pfam PF05638 Type VI secretion system effector, Hcp 5 139 3.7E-38 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS02105 faedae41d58ed891b6a91bda64836e99 167 Gene3D G3DSA:2.30.110.20 1 163 1.5E-46 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS02105 faedae41d58ed891b6a91bda64836e99 167 SUPERFAMILY SSF141452 1 162 2.35E-43 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS02105 faedae41d58ed891b6a91bda64836e99 167 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 15 146 1.8E-24 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS06860 f17e77f290b22f6c3fea56435083747e 205 SUPERFAMILY SSF48498 81 195 7.17E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS06860 f17e77f290b22f6c3fea56435083747e 205 Gene3D G3DSA:1.10.10.60 5 63 2.7E-12 T 29-03-2018 CVS48_RS06860 f17e77f290b22f6c3fea56435083747e 205 Gene3D G3DSA:1.10.357.10 64 196 3.6E-24 T 29-03-2018 CVS48_RS06860 f17e77f290b22f6c3fea56435083747e 205 SUPERFAMILY SSF46689 5 73 8.21E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS06860 f17e77f290b22f6c3fea56435083747e 205 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 123 196 2.9E-6 T 29-03-2018 CVS48_RS06860 f17e77f290b22f6c3fea56435083747e 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 5.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS13515 63d3747c8b12980169426c0143145cab 539 Gene3D G3DSA:3.40.50.980 5 196 3.7E-41 T 29-03-2018 CVS48_RS13515 63d3747c8b12980169426c0143145cab 539 SUPERFAMILY SSF56801 11 537 5.63E-150 T 29-03-2018 CVS48_RS13515 63d3747c8b12980169426c0143145cab 539 Pfam PF00501 AMP-binding enzyme 21 439 3.5E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS13515 63d3747c8b12980169426c0143145cab 539 Gene3D G3DSA:3.40.50.980 197 346 6.0E-44 T 29-03-2018 CVS48_RS13515 63d3747c8b12980169426c0143145cab 539 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 163 533 3.7E-184 T 29-03-2018 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 CVS48_RS13515 63d3747c8b12980169426c0143145cab 539 Gene3D G3DSA:2.30.38.10 347 431 5.2E-21 T 29-03-2018 CVS48_RS13515 63d3747c8b12980169426c0143145cab 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 447 525 4.8E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS13515 63d3747c8b12980169426c0143145cab 539 Gene3D G3DSA:3.30.300.30 433 539 2.3E-29 T 29-03-2018 CVS48_RS18210 13a177e51ad10e42d06ebf2fdb9f884c 378 Pfam PF15887 Putative zinc-binding metallo-peptidase 127 374 2.8E-101 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CVS48_RS18210 13a177e51ad10e42d06ebf2fdb9f884c 378 Gene3D G3DSA:3.40.390.10 158 317 2.8E-16 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CVS48_RS18210 13a177e51ad10e42d06ebf2fdb9f884c 378 Pfam PF10005 zinc-ribbon domain 28 120 1.2E-25 T 29-03-2018 IPR011201 Zinc-ribbon domain, bacteria CVS48_RS18210 13a177e51ad10e42d06ebf2fdb9f884c 378 PIRSF PIRSF012641 25 378 7.7E-124 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 Gene3D G3DSA:3.40.50.720 1 264 1.9E-65 T 29-03-2018 CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 Pfam PF00106 short chain dehydrogenase 8 194 7.4E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS24210 7b61e573ee112e7eba0e7bc9c1403ef4 264 SUPERFAMILY SSF51735 6 260 5.58E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 Pfam PF12801 4Fe-4S binding domain 108 150 7.0E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 373 495 3.1E-27 T 29-03-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 SUPERFAMILY SSF54862 186 367 4.47E-34 T 29-03-2018 CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 SUPERFAMILY SSF54862 118 140 4.47E-34 T 29-03-2018 CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 Gene3D G3DSA:3.30.70.20 289 303 0.083 T 29-03-2018 CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 Pfam PF13746 4Fe-4S dicluster domain 232 337 2.2E-42 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 285 296 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 Gene3D G3DSA:3.30.70.20 318 364 0.0026 T 29-03-2018 CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 Gene3D G3DSA:3.30.70.20 304 317 0.03 T 29-03-2018 CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 309 320 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 Gene3D G3DSA:2.60.40.10 373 494 9.0E-26 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 Gene3D G3DSA:3.30.70.20 235 288 8.2E-11 T 29-03-2018 CVS48_RS23145 4d905ecea6c9803da1038fcfb24c469f 496 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 54 484 1.0E-149 T 29-03-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 CVS48_RS16385 c3ea5034cab79dcbd6baa5cc023ca587 320 PIRSF PIRSF018266 1 319 8.5E-83 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS16385 c3ea5034cab79dcbd6baa5cc023ca587 320 Pfam PF04773 FecR protein 112 205 4.8E-15 T 29-03-2018 IPR006860 FecR protein CVS48_RS16385 c3ea5034cab79dcbd6baa5cc023ca587 320 Pfam PF16220 Domain of unknown function (DUF4880) 8 49 2.9E-12 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS05280 48b9be75e5965c9fb9c10129997424a1 473 Pfam PF01425 Amidase 28 452 4.9E-105 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS05280 48b9be75e5965c9fb9c10129997424a1 473 ProSitePatterns PS00571 Amidases signature. 156 187 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CVS48_RS05280 48b9be75e5965c9fb9c10129997424a1 473 Gene3D G3DSA:3.90.1300.10 3 473 4.1E-136 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS05280 48b9be75e5965c9fb9c10129997424a1 473 SUPERFAMILY SSF75304 7 470 1.83E-135 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS22050 cc5a049592b05c70680c2bbb38ec1018 197 SUPERFAMILY SSF46689 1 86 3.08E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS22050 cc5a049592b05c70680c2bbb38ec1018 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.6E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS22050 cc5a049592b05c70680c2bbb38ec1018 197 Gene3D G3DSA:1.10.357.10 1 197 6.8E-38 T 29-03-2018 CVS48_RS22050 cc5a049592b05c70680c2bbb38ec1018 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS22050 cc5a049592b05c70680c2bbb38ec1018 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS09825 199f74e717661c844fb60d9d27862f85 206 SUPERFAMILY SSF47616 72 202 1.07E-28 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS09825 199f74e717661c844fb60d9d27862f85 206 Gene3D G3DSA:1.20.1050.10 95 203 1.5E-23 T 29-03-2018 CVS48_RS09825 199f74e717661c844fb60d9d27862f85 206 SUPERFAMILY SSF52833 1 85 1.98E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS09825 199f74e717661c844fb60d9d27862f85 206 Gene3D G3DSA:3.40.30.10 2 94 7.8E-27 T 29-03-2018 CVS48_RS09825 199f74e717661c844fb60d9d27862f85 206 Pfam PF13417 Glutathione S-transferase, N-terminal domain 8 78 1.7E-13 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS09825 199f74e717661c844fb60d9d27862f85 206 Pfam PF00043 Glutathione S-transferase, C-terminal domain 121 195 2.6E-7 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS23240 67a83c28c86a0879e7892028c30649d2 190 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CVS48_RS23240 67a83c28c86a0879e7892028c30649d2 190 PIRSF PIRSF000847 1 190 2.2E-44 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CVS48_RS23240 67a83c28c86a0879e7892028c30649d2 190 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 76 1.3E-16 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CVS48_RS23240 67a83c28c86a0879e7892028c30649d2 190 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 186 1.0E-50 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 Gene3D G3DSA:1.10.10.10 1 83 9.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 Pfam PF03466 LysR substrate binding domain 88 294 5.0E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 Gene3D G3DSA:3.40.190.10 88 182 1.0E-11 T 29-03-2018 CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 SUPERFAMILY SSF46785 1 87 1.31E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.3E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 SUPERFAMILY SSF53850 89 294 1.63E-28 T 29-03-2018 CVS48_RS21340 057bcb5106c282d6364f649ecdc0b758 295 Gene3D G3DSA:3.40.190.10 183 262 7.8E-14 T 29-03-2018 CVS48_RS21030 7000ffdbb69b0f9796d7d1fcf76d85d4 338 Pfam PF00005 ABC transporter 47 198 1.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS21030 7000ffdbb69b0f9796d7d1fcf76d85d4 338 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS21030 7000ffdbb69b0f9796d7d1fcf76d85d4 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 250 314 1.7E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS21030 7000ffdbb69b0f9796d7d1fcf76d85d4 338 SMART SM00382 56 248 3.8E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21030 7000ffdbb69b0f9796d7d1fcf76d85d4 338 Gene3D G3DSA:3.40.50.300 7 338 6.9E-78 T 29-03-2018 CVS48_RS21030 7000ffdbb69b0f9796d7d1fcf76d85d4 338 SUPERFAMILY SSF52540 55 332 4.15E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21030 7000ffdbb69b0f9796d7d1fcf76d85d4 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 334 1.1E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS26735 4fe85a657e472c13052c0de680dcb46a 100 SMART SM00886 2 96 1.8E-14 T 29-03-2018 IPR013097 Stress responsive alpha-beta barrel CVS48_RS26735 4fe85a657e472c13052c0de680dcb46a 100 Gene3D G3DSA:3.30.70.100 1 100 2.6E-17 T 29-03-2018 CVS48_RS26735 4fe85a657e472c13052c0de680dcb46a 100 SUPERFAMILY SSF54909 1 98 9.97E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS26735 4fe85a657e472c13052c0de680dcb46a 100 Pfam PF07876 Stress responsive A/B Barrel Domain 4 94 3.9E-11 T 29-03-2018 IPR013097 Stress responsive alpha-beta barrel CVS48_RS28060 367209e2eca1179cef1472608cda77b7 291 SUPERFAMILY SSF53697 101 265 4.89E-23 T 29-03-2018 CVS48_RS28060 367209e2eca1179cef1472608cda77b7 291 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 78 4.0E-12 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CVS48_RS28060 367209e2eca1179cef1472608cda77b7 291 Pfam PF01380 SIS domain 134 244 6.9E-15 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CVS48_RS28060 367209e2eca1179cef1472608cda77b7 291 SUPERFAMILY SSF46689 6 79 2.51E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS28060 367209e2eca1179cef1472608cda77b7 291 Gene3D G3DSA:3.40.50.10490 88 279 2.9E-24 T 29-03-2018 CVS48_RS28060 367209e2eca1179cef1472608cda77b7 291 Gene3D G3DSA:1.10.10.10 3 82 2.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15975 adbe7709012df7647fc4117ae1b6e380 435 SUPERFAMILY SSF51679 4 428 1.14E-119 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CVS48_RS15975 adbe7709012df7647fc4117ae1b6e380 435 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 6 422 7.2E-156 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CVS48_RS15975 adbe7709012df7647fc4117ae1b6e380 435 Pfam PF00296 Luciferase-like monooxygenase 18 380 1.2E-59 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CVS48_RS15975 adbe7709012df7647fc4117ae1b6e380 435 PIRSF PIRSF000337 2 434 6.7E-150 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CVS48_RS15975 adbe7709012df7647fc4117ae1b6e380 435 Gene3D G3DSA:3.20.20.30 2 432 4.6E-99 T 29-03-2018 CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 Gene3D G3DSA:3.90.1150.10 3 76 1.8E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 Gene3D G3DSA:3.40.640.10 77 302 6.1E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 Pfam PF00155 Aminotransferase class I and II 31 393 2.2E-78 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 Gene3D G3DSA:3.90.1150.10 304 399 3.2E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 SUPERFAMILY SSF53383 3 397 1.28E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 246 259 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 PRINTS PR00799 Aspartate aminotransferase signature 209 221 4.9E-40 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 PRINTS PR00799 Aspartate aminotransferase signature 276 301 4.9E-40 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 PRINTS PR00799 Aspartate aminotransferase signature 344 362 4.9E-40 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CVS48_RS21950 7231436f9c94497d131765ff699ee5bd 399 PRINTS PR00799 Aspartate aminotransferase signature 178 197 4.9E-40 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CVS48_RS21375 fc90142f55fa59e50f2207ebc7838b2c 124 Gene3D G3DSA:2.102.10.10 14 124 7.3E-16 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS21375 fc90142f55fa59e50f2207ebc7838b2c 124 Pfam PF13806 Rieske-like [2Fe-2S] domain 19 123 1.1E-33 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CVS48_RS21375 fc90142f55fa59e50f2207ebc7838b2c 124 SUPERFAMILY SSF50022 18 123 6.54E-31 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS21375 fc90142f55fa59e50f2207ebc7838b2c 124 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 19 123 5.7E-29 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 SUPERFAMILY SSF46934 3 56 7.35E-14 T 29-03-2018 IPR009060 UBA-like GO:0005515 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 Gene3D G3DSA:3.30.479.20 58 156 2.6E-23 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 SUPERFAMILY SSF54713 56 147 5.89E-23 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 287 5.8E-91 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 288 77.35 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 Gene3D G3DSA:1.10.8.10 1 56 3.6E-19 T 29-03-2018 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 Pfam PF00889 Elongation factor TS 73 271 3.0E-68 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 SUPERFAMILY SSF54713 151 288 3.66E-46 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS17125 f6c59bf735d175c1c4833b463949dff9 292 Gene3D G3DSA:3.30.479.20 157 287 4.8E-47 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CVS48_RS11660 ba3ec741928a8d990c01320bfea4bcb1 79 Gene3D G3DSA:3.40.1620.10 4 79 1.8E-10 T 29-03-2018 CVS48_RS11660 ba3ec741928a8d990c01320bfea4bcb1 79 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 47 2.7E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CVS48_RS11660 ba3ec741928a8d990c01320bfea4bcb1 79 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 44 1.4E-5 T 29-03-2018 CVS48_RS11660 ba3ec741928a8d990c01320bfea4bcb1 79 SUPERFAMILY SSF143120 5 46 2.22E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CVS48_RS09820 331e49c0849862280770810ffd5e96de 272 SUPERFAMILY SSF46785 24 93 2.72E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09820 331e49c0849862280770810ffd5e96de 272 Pfam PF09339 IclR helix-turn-helix domain 25 72 3.5E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS09820 331e49c0849862280770810ffd5e96de 272 Gene3D G3DSA:1.10.10.10 20 90 4.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09820 331e49c0849862280770810ffd5e96de 272 Gene3D G3DSA:3.30.450.40 91 270 2.6E-50 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09820 331e49c0849862280770810ffd5e96de 272 SUPERFAMILY SSF55781 86 267 6.34E-45 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09820 331e49c0849862280770810ffd5e96de 272 SMART SM00346 23 110 1.0E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS09820 331e49c0849862280770810ffd5e96de 272 Pfam PF01614 Bacterial transcriptional regulator 140 263 9.3E-21 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS28035 e1a294553a3ff1c47bd4b3193c2856e1 299 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 73 5.0E-11 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS28035 e1a294553a3ff1c47bd4b3193c2856e1 299 SUPERFAMILY SSF161098 91 281 8.37E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28035 e1a294553a3ff1c47bd4b3193c2856e1 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 297 2.1E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28035 e1a294553a3ff1c47bd4b3193c2856e1 299 Gene3D G3DSA:1.10.3720.10 24 286 3.5E-46 T 29-03-2018 CVS48_RS05315 f692218b1d931b6bbb8c966fa75c5230 296 SUPERFAMILY SSF46689 194 241 3.94E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05315 f692218b1d931b6bbb8c966fa75c5230 296 SUPERFAMILY SSF46689 243 294 3.58E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05315 f692218b1d931b6bbb8c966fa75c5230 296 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 244 286 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS05315 f692218b1d931b6bbb8c966fa75c5230 296 Gene3D G3DSA:1.10.10.60 103 245 2.7E-13 T 29-03-2018 CVS48_RS05315 f692218b1d931b6bbb8c966fa75c5230 296 Pfam PF12833 Helix-turn-helix domain 213 291 3.1E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS05315 f692218b1d931b6bbb8c966fa75c5230 296 Gene3D G3DSA:1.10.10.60 246 296 1.2E-16 T 29-03-2018 CVS48_RS05315 f692218b1d931b6bbb8c966fa75c5230 296 SMART SM00342 207 290 8.4E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS07230 06dab36b600bc2938c6578c92dfaf486 184 Gene3D G3DSA:1.20.1200.10 17 183 9.2E-63 T 29-03-2018 CVS48_RS07230 06dab36b600bc2938c6578c92dfaf486 184 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 177 6.2E-64 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CVS48_RS07230 06dab36b600bc2938c6578c92dfaf486 184 Pfam PF01923 Cobalamin adenosyltransferase 8 165 1.2E-56 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CVS48_RS07230 06dab36b600bc2938c6578c92dfaf486 184 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 28 177 5.0E-61 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CVS48_RS07230 06dab36b600bc2938c6578c92dfaf486 184 SUPERFAMILY SSF89028 8 178 4.51E-59 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 57 2.1E-17 T 29-03-2018 CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 7.0E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 7.0E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 7.0E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 SMART SM00344 11 120 3.2E-32 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 SUPERFAMILY SSF46785 11 70 2.49E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 SUPERFAMILY SSF54909 73 158 7.64E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 Pfam PF01037 Lrp/AsnC ligand binding domain 77 149 5.9E-15 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 Gene3D G3DSA:3.30.70.920 61 159 6.8E-19 T 29-03-2018 CVS48_RS04875 194ab799be8eb90c07dbf354c7b8e0f2 162 Gene3D G3DSA:1.10.10.10 6 60 2.0E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06495 944e2f73c6f92be25f0213e87efacaef 106 Gene3D G3DSA:2.30.30.30 2 92 7.5E-27 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CVS48_RS06495 944e2f73c6f92be25f0213e87efacaef 106 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06495 944e2f73c6f92be25f0213e87efacaef 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 101 3.3E-30 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06495 944e2f73c6f92be25f0213e87efacaef 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 3.6E-22 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06495 944e2f73c6f92be25f0213e87efacaef 106 SUPERFAMILY SSF50104 3 100 2.06E-28 T 29-03-2018 IPR008991 Translation protein SH3-like domain CVS48_RS06495 944e2f73c6f92be25f0213e87efacaef 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 96 18.937 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 Gene3D G3DSA:1.10.10.10 5 88 2.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 5.8E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 Gene3D G3DSA:3.40.190.10 184 270 1.6E-21 T 29-03-2018 CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 Pfam PF03466 LysR substrate binding domain 93 299 9.6E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 SUPERFAMILY SSF46785 11 116 8.35E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 SUPERFAMILY SSF53850 95 300 1.63E-38 T 29-03-2018 CVS48_RS18520 faa700da0d64e5b5bcee07b7ecb01356 302 Gene3D G3DSA:3.40.190.10 94 183 7.5E-21 T 29-03-2018 CVS48_RS21900 320c8ecf6930e33057d3fb477e91b79a 64 Pfam PF04384 Iron-sulphur cluster assembly 1 63 1.1E-34 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CVS48_RS21900 320c8ecf6930e33057d3fb477e91b79a 64 PIRSF PIRSF039003 1 64 4.3E-36 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CVS48_RS21900 320c8ecf6930e33057d3fb477e91b79a 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 64 6.1E-36 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CVS48_RS21900 320c8ecf6930e33057d3fb477e91b79a 64 Gene3D G3DSA:1.10.10.600 1 62 9.5E-35 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CVS48_RS21900 320c8ecf6930e33057d3fb477e91b79a 64 SUPERFAMILY SSF140319 1 62 3.14E-28 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CVS48_RS04335 7fe637cb04967146d5a8e602a446066e 499 Pfam PF06742 Protein of unknown function (DUF1214) 359 462 4.1E-30 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 CVS48_RS04335 7fe637cb04967146d5a8e602a446066e 499 Gene3D G3DSA:2.60.40.1610 55 229 9.9E-41 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 CVS48_RS04335 7fe637cb04967146d5a8e602a446066e 499 Gene3D G3DSA:2.60.120.600 306 482 8.9E-43 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 CVS48_RS04335 7fe637cb04967146d5a8e602a446066e 499 SUPERFAMILY SSF160935 27 477 3.53E-103 T 29-03-2018 CVS48_RS04335 7fe637cb04967146d5a8e602a446066e 499 Pfam PF06863 Protein of unknown function (DUF1254) 82 212 8.1E-36 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 CVS48_RS01250 674abd3dba06b858d8070930c485376e 256 Pfam PF09339 IclR helix-turn-helix domain 15 61 6.5E-8 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS01250 674abd3dba06b858d8070930c485376e 256 SMART SM00346 9 98 1.2E-8 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS01250 674abd3dba06b858d8070930c485376e 256 SUPERFAMILY SSF55781 66 252 3.27E-32 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS01250 674abd3dba06b858d8070930c485376e 256 Gene3D G3DSA:1.10.10.10 9 71 1.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01250 674abd3dba06b858d8070930c485376e 256 Pfam PF01614 Bacterial transcriptional regulator 130 250 6.8E-6 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS01250 674abd3dba06b858d8070930c485376e 256 SUPERFAMILY SSF46785 9 80 2.19E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01250 674abd3dba06b858d8070930c485376e 256 Gene3D G3DSA:3.30.450.40 74 255 3.3E-28 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 435 3.3E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 SMART SM00388 216 282 5.3E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 413 6.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 435 6.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 6.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 SUPERFAMILY SSF55874 271 434 6.68E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 SMART SM00387 323 438 3.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 Gene3D G3DSA:3.30.565.10 275 438 2.3E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 Gene3D G3DSA:1.10.287.130 204 274 7.0E-9 T 29-03-2018 CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 278 1.9E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS10745 a86f4320ec73c360d9d846e8c8148c79 449 SUPERFAMILY SSF47384 199 278 6.28E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS13975 80869840c255981b197f19f0478fe032 432 Pfam PF13460 NAD(P)H-binding 7 147 1.1E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13975 80869840c255981b197f19f0478fe032 432 SUPERFAMILY SSF51735 1 216 4.8E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13975 80869840c255981b197f19f0478fe032 432 Pfam PF13781 DoxX-like family 317 419 1.2E-25 T 29-03-2018 IPR025695 DoxX-like family CVS48_RS13975 80869840c255981b197f19f0478fe032 432 Gene3D G3DSA:3.40.50.720 1 288 2.8E-34 T 29-03-2018 CVS48_RS21940 d90716efe862661e361ef90b86acc54f 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 148 1.5E-42 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CVS48_RS21940 d90716efe862661e361ef90b86acc54f 163 SMART SM00226 3 152 1.4E-51 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CVS48_RS21940 d90716efe862661e361ef90b86acc54f 163 Gene3D G3DSA:3.40.50.2300 1 161 9.5E-55 T 29-03-2018 CVS48_RS21940 d90716efe862661e361ef90b86acc54f 163 SUPERFAMILY SSF52788 1 153 3.66E-54 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CVS48_RS21940 d90716efe862661e361ef90b86acc54f 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 6.3E-23 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CVS48_RS21940 d90716efe862661e361ef90b86acc54f 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 6.3E-23 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CVS48_RS21940 d90716efe862661e361ef90b86acc54f 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 6.3E-23 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CVS48_RS21940 d90716efe862661e361ef90b86acc54f 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 6.3E-23 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CVS48_RS20425 563d9c995a3fa690018b255869083131 117 Gene3D G3DSA:3.30.70.1060 1 115 3.3E-34 T 29-03-2018 CVS48_RS20425 563d9c995a3fa690018b255869083131 117 SUPERFAMILY SSF54909 1 114 2.04E-31 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS20425 563d9c995a3fa690018b255869083131 117 Pfam PF03795 YCII-related domain 1 112 2.1E-18 T 29-03-2018 IPR005545 YCII-related CVS48_RS20570 c05da96f04550d987e65447efb4e9211 412 SUPERFAMILY SSF103473 8 399 3.92E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS20570 c05da96f04550d987e65447efb4e9211 412 Gene3D G3DSA:1.20.1250.20 6 191 7.9E-19 T 29-03-2018 CVS48_RS20570 c05da96f04550d987e65447efb4e9211 412 Pfam PF05977 Transmembrane secretion effector 7 405 1.2E-28 T 29-03-2018 IPR010290 Transmembrane secretion effector CVS48_RS20570 c05da96f04550d987e65447efb4e9211 412 Gene3D G3DSA:1.20.1250.20 216 412 6.7E-13 T 29-03-2018 CVS48_RS07950 d156b1b6138ae91b55bed31eb9b7cf0a 230 Pfam PF00072 Response regulator receiver domain 4 114 4.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS07950 d156b1b6138ae91b55bed31eb9b7cf0a 230 SUPERFAMILY SSF52172 1 129 2.13E-38 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS07950 d156b1b6138ae91b55bed31eb9b7cf0a 230 SMART SM00448 2 114 8.3E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS07950 d156b1b6138ae91b55bed31eb9b7cf0a 230 SUPERFAMILY SSF46689 165 222 1.47E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS07950 d156b1b6138ae91b55bed31eb9b7cf0a 230 Gene3D G3DSA:3.40.50.2300 1 141 1.3E-31 T 29-03-2018 CVS48_RS07950 d156b1b6138ae91b55bed31eb9b7cf0a 230 Gene3D G3DSA:1.10.10.60 166 227 1.6E-11 T 29-03-2018 CVS48_RS27510 94f2ce0923720fb33b6126c88150ccde 300 Gene3D G3DSA:1.10.3660.10 197 300 4.9E-25 T 29-03-2018 CVS48_RS27510 94f2ce0923720fb33b6126c88150ccde 300 SUPERFAMILY SSF51735 20 185 6.68E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS27510 94f2ce0923720fb33b6126c88150ccde 300 Pfam PF02153 Prephenate dehydrogenase 32 287 2.9E-66 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CVS48_RS27510 94f2ce0923720fb33b6126c88150ccde 300 SUPERFAMILY SSF48179 189 297 2.61E-31 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS27510 94f2ce0923720fb33b6126c88150ccde 300 Gene3D G3DSA:3.40.50.720 20 187 2.9E-29 T 29-03-2018 CVS48_RS25225 fe79367abc136483d5f4f5cecc805208 398 Gene3D G3DSA:3.40.50.10540 1 398 1.7E-140 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS25225 fe79367abc136483d5f4f5cecc805208 398 SUPERFAMILY SSF89796 1 398 2.09E-130 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS25225 fe79367abc136483d5f4f5cecc805208 398 Pfam PF02515 CoA-transferase family III 4 374 2.4E-115 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS25850 031745a4728c61b213a4a8fcdfbafdaf 483 ProSitePatterns PS00216 Sugar transport proteins signature 1. 100 116 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS25850 031745a4728c61b213a4a8fcdfbafdaf 483 Pfam PF07690 Major Facilitator Superfamily 51 368 4.5E-35 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS25850 031745a4728c61b213a4a8fcdfbafdaf 483 Gene3D G3DSA:1.20.1250.20 37 236 1.4E-31 T 29-03-2018 CVS48_RS25850 031745a4728c61b213a4a8fcdfbafdaf 483 SUPERFAMILY SSF103473 32 467 2.22E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS25850 031745a4728c61b213a4a8fcdfbafdaf 483 Gene3D G3DSA:1.20.1250.20 282 472 9.2E-22 T 29-03-2018 CVS48_RS04025 4cc111367d8f30239867f15b800db1ee 336 SUPERFAMILY SSF52540 9 267 1.54E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04025 4cc111367d8f30239867f15b800db1ee 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 331 8.3E-29 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS04025 4cc111367d8f30239867f15b800db1ee 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 311 6.0E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS04025 4cc111367d8f30239867f15b800db1ee 336 SMART SM00382 53 245 4.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS04025 4cc111367d8f30239867f15b800db1ee 336 Pfam PF00005 ABC transporter 45 196 6.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS04025 4cc111367d8f30239867f15b800db1ee 336 Gene3D G3DSA:3.40.50.300 5 336 9.0E-81 T 29-03-2018 CVS48_RS04025 4cc111367d8f30239867f15b800db1ee 336 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13425 2f695969cbea63347f7bc9d62b88162d 396 Gene3D G3DSA:3.30.470.20 188 392 6.7E-43 T 29-03-2018 CVS48_RS13425 2f695969cbea63347f7bc9d62b88162d 396 SUPERFAMILY SSF52440 10 107 5.47E-25 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS13425 2f695969cbea63347f7bc9d62b88162d 396 Gene3D G3DSA:3.30.1490.20 125 187 1.6E-14 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS13425 2f695969cbea63347f7bc9d62b88162d 396 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 14 376 40.807 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CVS48_RS13425 2f695969cbea63347f7bc9d62b88162d 396 SUPERFAMILY SSF56059 110 311 6.19E-56 T 29-03-2018 CVS48_RS13425 2f695969cbea63347f7bc9d62b88162d 396 Pfam PF02222 ATP-grasp domain 120 291 1.1E-45 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CVS48_RS13425 2f695969cbea63347f7bc9d62b88162d 396 Gene3D G3DSA:3.40.50.20 14 109 1.7E-22 T 29-03-2018 CVS48_RS13425 2f695969cbea63347f7bc9d62b88162d 396 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 15 379 3.7E-115 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CVS48_RS13425 2f695969cbea63347f7bc9d62b88162d 396 SUPERFAMILY SSF51246 315 390 6.43E-16 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CVS48_RS07000 766f40365dc0d1452052ae0f761a740c 291 Pfam PF01370 NAD dependent epimerase/dehydratase family 82 203 6.6E-8 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS07000 766f40365dc0d1452052ae0f761a740c 291 Gene3D G3DSA:3.40.50.720 1 62 5.1E-5 T 29-03-2018 CVS48_RS07000 766f40365dc0d1452052ae0f761a740c 291 Gene3D G3DSA:3.40.50.720 67 285 4.4E-28 T 29-03-2018 CVS48_RS07000 766f40365dc0d1452052ae0f761a740c 291 SUPERFAMILY SSF51735 1 280 8.28E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19585 44c5826352a6276ba1d49dcd277b8b74 242 Pfam PF00005 ABC transporter 19 167 4.5E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19585 44c5826352a6276ba1d49dcd277b8b74 242 SUPERFAMILY SSF52540 3 237 1.5E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19585 44c5826352a6276ba1d49dcd277b8b74 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS19585 44c5826352a6276ba1d49dcd277b8b74 242 Gene3D G3DSA:3.40.50.300 1 242 4.7E-74 T 29-03-2018 CVS48_RS19585 44c5826352a6276ba1d49dcd277b8b74 242 SMART SM00382 28 215 9.0E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19585 44c5826352a6276ba1d49dcd277b8b74 242 PIRSF PIRSF039085 1 242 1.2E-110 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS02570 35c7777b79a8ddc5e32ef03a2a696bda 370 SUPERFAMILY SSF54593 7 353 5.29E-82 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS02570 35c7777b79a8ddc5e32ef03a2a696bda 370 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 176 286 2.4E-13 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS02570 35c7777b79a8ddc5e32ef03a2a696bda 370 Gene3D G3DSA:3.10.180.10 5 165 5.5E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS02570 35c7777b79a8ddc5e32ef03a2a696bda 370 PIRSF PIRSF009283 1 367 4.0E-123 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CVS48_RS02570 35c7777b79a8ddc5e32ef03a2a696bda 370 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 8 153 8.4E-65 T 29-03-2018 CVS48_RS02570 35c7777b79a8ddc5e32ef03a2a696bda 370 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 16 365 8.2E-118 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CVS48_RS02570 35c7777b79a8ddc5e32ef03a2a696bda 370 Gene3D G3DSA:3.10.180.10 170 367 1.4E-60 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS22075 2336cc23a820120a5dc39b2403e5d6ad 164 SUPERFAMILY SSF55729 2 150 1.2E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS22075 2336cc23a820120a5dc39b2403e5d6ad 164 Gene3D G3DSA:3.40.630.30 2 158 2.8E-34 T 29-03-2018 CVS48_RS22075 2336cc23a820120a5dc39b2403e5d6ad 164 Pfam PF00583 Acetyltransferase (GNAT) family 48 134 6.8E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS01700 5fc58494a63a13389bfcf07ac898d2e8 455 Pfam PF02321 Outer membrane efflux protein 276 450 6.9E-23 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS01700 5fc58494a63a13389bfcf07ac898d2e8 455 Pfam PF02321 Outer membrane efflux protein 61 239 1.3E-17 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS01700 5fc58494a63a13389bfcf07ac898d2e8 455 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 7 451 1.0E-80 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS01700 5fc58494a63a13389bfcf07ac898d2e8 455 SUPERFAMILY SSF56954 3 452 5.23E-88 T 29-03-2018 CVS48_RS01700 5fc58494a63a13389bfcf07ac898d2e8 455 Gene3D G3DSA:1.20.1600.10 18 452 9.9E-78 T 29-03-2018 CVS48_RS09015 3b4ca147a1c225eb5095800236b2ffc7 307 Gene3D G3DSA:3.40.190.10 181 274 2.0E-13 T 29-03-2018 CVS48_RS09015 3b4ca147a1c225eb5095800236b2ffc7 307 SUPERFAMILY SSF53850 94 301 5.12E-30 T 29-03-2018 CVS48_RS09015 3b4ca147a1c225eb5095800236b2ffc7 307 Gene3D G3DSA:3.40.190.10 92 180 5.4E-17 T 29-03-2018 CVS48_RS09015 3b4ca147a1c225eb5095800236b2ffc7 307 SUPERFAMILY SSF46785 9 90 1.98E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09015 3b4ca147a1c225eb5095800236b2ffc7 307 Pfam PF03466 LysR substrate binding domain 92 298 2.4E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS09015 3b4ca147a1c225eb5095800236b2ffc7 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 66 3.4E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS09015 3b4ca147a1c225eb5095800236b2ffc7 307 Gene3D G3DSA:1.10.10.10 1 87 1.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10640 4e8d3eb0bbdc4e6031d09ae281651b33 427 PIRSF PIRSF000521 14 426 6.8E-21 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS10640 4e8d3eb0bbdc4e6031d09ae281651b33 427 Gene3D G3DSA:3.90.1150.10 314 427 8.5E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS10640 4e8d3eb0bbdc4e6031d09ae281651b33 427 Gene3D G3DSA:3.40.640.10 40 313 3.9E-73 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS10640 4e8d3eb0bbdc4e6031d09ae281651b33 427 SUPERFAMILY SSF53383 1 426 4.95E-114 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS10640 4e8d3eb0bbdc4e6031d09ae281651b33 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS10640 4e8d3eb0bbdc4e6031d09ae281651b33 427 Pfam PF00202 Aminotransferase class-III 14 423 9.3E-84 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS26065 dd364782e1bad88cb366a2bf744b200b 246 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 203 1.2E-36 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS26065 dd364782e1bad88cb366a2bf744b200b 246 Gene3D G3DSA:3.40.225.10 13 246 2.9E-51 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS26065 dd364782e1bad88cb366a2bf744b200b 246 SUPERFAMILY SSF53639 17 233 1.96E-50 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS26065 dd364782e1bad88cb366a2bf744b200b 246 SMART SM01007 22 203 2.9E-37 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 Gene3D G3DSA:3.40.50.720 2 260 2.2E-55 T 29-03-2018 CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 9.1E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 9.1E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 9.1E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 9.1E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 9.1E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 9.1E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 SUPERFAMILY SSF51735 10 256 8.7E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 255 4.8E-40 T 29-03-2018 CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 6.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11275 279c1257c559741e1677fa4c1d445027 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 6.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS07625 9ad8a81dd118da4289bf4d6e334b4d10 102 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 102 2.6E-24 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CVS48_RS07625 9ad8a81dd118da4289bf4d6e334b4d10 102 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 102 22.349 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CVS48_RS07625 9ad8a81dd118da4289bf4d6e334b4d10 102 SUPERFAMILY SSF141000 3 100 1.31E-23 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CVS48_RS07625 9ad8a81dd118da4289bf4d6e334b4d10 102 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 97 1.7E-19 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CVS48_RS26105 d65ca44dc89b51f97b07a576ffce86b0 488 Gene3D G3DSA:3.30.450.20 59 169 2.3E-16 T 29-03-2018 CVS48_RS26105 d65ca44dc89b51f97b07a576ffce86b0 488 Gene3D G3DSA:3.30.450.20 170 285 1.6E-9 T 29-03-2018 CVS48_RS26105 d65ca44dc89b51f97b07a576ffce86b0 488 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 320 486 9.5E-53 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS26105 d65ca44dc89b51f97b07a576ffce86b0 488 SUPERFAMILY SSF55073 329 486 1.18E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS26105 d65ca44dc89b51f97b07a576ffce86b0 488 Gene3D G3DSA:3.30.70.270 317 488 5.2E-55 T 29-03-2018 CVS48_RS26105 d65ca44dc89b51f97b07a576ffce86b0 488 Pfam PF02743 Cache domain 43 214 1.4E-15 T 29-03-2018 IPR033479 Double Cache domain 1 CVS48_RS26105 d65ca44dc89b51f97b07a576ffce86b0 488 SMART SM00267 313 488 1.6E-60 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS26105 d65ca44dc89b51f97b07a576ffce86b0 488 Pfam PF00990 Diguanylate cyclase, GGDEF domain 324 484 5.3E-50 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS20565 83494fe009230931ee37416793a5a510 263 Hamap MF_01974 Methionine aminopeptidase [map]. 5 252 40.294 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS20565 83494fe009230931ee37416793a5a510 263 SUPERFAMILY SSF55920 6 256 5.23E-93 T 29-03-2018 IPR000994 Peptidase M24 CVS48_RS20565 83494fe009230931ee37416793a5a510 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 6 250 3.3E-94 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS20565 83494fe009230931ee37416793a5a510 263 Pfam PF00557 Metallopeptidase family M24 15 243 1.0E-54 T 29-03-2018 IPR000994 Peptidase M24 CVS48_RS20565 83494fe009230931ee37416793a5a510 263 Gene3D G3DSA:3.90.230.10 1 259 8.7E-86 T 29-03-2018 CVS48_RS20565 83494fe009230931ee37416793a5a510 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 169 187 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS20565 83494fe009230931ee37416793a5a510 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 163 175 3.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS20565 83494fe009230931ee37416793a5a510 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 93 109 3.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS20565 83494fe009230931ee37416793a5a510 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 194 206 3.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS20565 83494fe009230931ee37416793a5a510 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 71 84 3.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CVS48_RS16390 cc27533dceedd1295a0a30406277665a 815 Gene3D G3DSA:2.40.170.20 268 815 2.3E-80 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS16390 cc27533dceedd1295a0a30406277665a 815 Pfam PF07715 TonB-dependent Receptor Plug Domain 159 258 1.4E-16 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS16390 cc27533dceedd1295a0a30406277665a 815 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 161 814 3.8E-111 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS16390 cc27533dceedd1295a0a30406277665a 815 Pfam PF00593 TonB dependent receptor 363 814 1.7E-51 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS16390 cc27533dceedd1295a0a30406277665a 815 SUPERFAMILY SSF56935 121 815 3.66E-125 T 29-03-2018 CVS48_RS16390 cc27533dceedd1295a0a30406277665a 815 SMART SM00965 68 119 4.0E-12 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS16390 cc27533dceedd1295a0a30406277665a 815 Pfam PF07660 Secretin and TonB N terminus short domain 70 118 1.9E-7 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS16390 cc27533dceedd1295a0a30406277665a 815 Gene3D G3DSA:2.170.130.10 115 267 1.2E-21 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 ProSitePatterns PS00622 LuxR-type HTH domain signature. 250 277 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 Gene3D G3DSA:3.40.50.2300 3 230 1.7E-36 T 29-03-2018 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 SUPERFAMILY SSF52172 4 132 5.27E-38 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 SUPERFAMILY SSF46894 225 294 1.02E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 SMART SM00421 233 290 1.3E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 Gene3D G3DSA:1.10.10.10 236 295 2.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 266 278 7.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 250 266 7.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 236 250 7.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 SMART SM00448 7 120 9.6E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 Pfam PF00196 Bacterial regulatory proteins, luxR family 236 290 2.6E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS04825 a8cde6fc1d5236e3bca695b0698a45bf 297 Pfam PF00072 Response regulator receiver domain 9 120 7.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18125 e570a9baa73ff399916a2f80a9f175f4 192 SUPERFAMILY SSF88659 87 157 4.11E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS18125 e570a9baa73ff399916a2f80a9f175f4 192 Pfam PF08281 Sigma-70, region 4 105 157 1.8E-10 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS18125 e570a9baa73ff399916a2f80a9f175f4 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 154 1.9E-20 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS18125 e570a9baa73ff399916a2f80a9f175f4 192 Gene3D G3DSA:1.10.1740.10 2 75 1.7E-14 T 29-03-2018 CVS48_RS18125 e570a9baa73ff399916a2f80a9f175f4 192 Pfam PF04542 Sigma-70 region 2 8 74 2.6E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS18125 e570a9baa73ff399916a2f80a9f175f4 192 SUPERFAMILY SSF88946 4 88 7.85E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS18125 e570a9baa73ff399916a2f80a9f175f4 192 Gene3D G3DSA:1.10.10.10 76 167 4.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18970 ff236eded6374a0f6a1a20576f2467b7 588 Pfam PF05199 GMC oxidoreductase 448 570 8.9E-21 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS18970 ff236eded6374a0f6a1a20576f2467b7 588 Pfam PF00732 GMC oxidoreductase 234 347 2.8E-14 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS18970 ff236eded6374a0f6a1a20576f2467b7 588 SUPERFAMILY SSF54373 417 488 8.63E-7 T 29-03-2018 CVS48_RS18970 ff236eded6374a0f6a1a20576f2467b7 588 Gene3D G3DSA:3.50.50.60 3 585 2.7E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18970 ff236eded6374a0f6a1a20576f2467b7 588 SUPERFAMILY SSF51905 520 581 6.05E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18970 ff236eded6374a0f6a1a20576f2467b7 588 SUPERFAMILY SSF51905 8 341 6.05E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14375 94b6d0e0ff7ed1294ba5735003c03094 397 Gene3D G3DSA:2.40.50.100 169 199 0.56 T 29-03-2018 CVS48_RS14375 94b6d0e0ff7ed1294ba5735003c03094 397 Gene3D G3DSA:1.10.287.470 138 168 6.4E-12 T 29-03-2018 CVS48_RS14375 94b6d0e0ff7ed1294ba5735003c03094 397 SUPERFAMILY SSF111369 163 274 2.75E-10 T 29-03-2018 CVS48_RS14375 94b6d0e0ff7ed1294ba5735003c03094 397 Pfam PF00529 HlyD membrane-fusion protein of T1SS 29 352 8.9E-12 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS14375 94b6d0e0ff7ed1294ba5735003c03094 397 Gene3D G3DSA:2.40.50.100 52 137 1.9E-11 T 29-03-2018 CVS48_RS14375 94b6d0e0ff7ed1294ba5735003c03094 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 218 296 4.2E-14 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS14375 94b6d0e0ff7ed1294ba5735003c03094 397 Gene3D G3DSA:2.40.50.100 216 355 4.0E-8 T 29-03-2018 CVS48_RS14375 94b6d0e0ff7ed1294ba5735003c03094 397 SUPERFAMILY SSF111369 52 108 9.42E-7 T 29-03-2018 CVS48_RS14375 94b6d0e0ff7ed1294ba5735003c03094 397 SUPERFAMILY SSF111369 122 182 6.41E-5 T 29-03-2018 CVS48_RS28445 96790031f5fb90024dfc7bdc035ea9f4 266 Pfam PF00970 Oxidoreductase FAD-binding domain 23 106 2.6E-4 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CVS48_RS28445 96790031f5fb90024dfc7bdc035ea9f4 266 SUPERFAMILY SSF52343 113 266 9.43E-30 T 29-03-2018 CVS48_RS28445 96790031f5fb90024dfc7bdc035ea9f4 266 Gene3D G3DSA:3.40.50.80 107 266 4.6E-24 T 29-03-2018 CVS48_RS28445 96790031f5fb90024dfc7bdc035ea9f4 266 PRINTS PR00410 Phenol hydroxylase reductase family signature 120 139 5.7E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS28445 96790031f5fb90024dfc7bdc035ea9f4 266 PRINTS PR00410 Phenol hydroxylase reductase family signature 145 154 5.7E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS28445 96790031f5fb90024dfc7bdc035ea9f4 266 PRINTS PR00410 Phenol hydroxylase reductase family signature 36 48 5.7E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CVS48_RS28445 96790031f5fb90024dfc7bdc035ea9f4 266 Gene3D G3DSA:2.40.30.10 1 105 3.2E-15 T 29-03-2018 CVS48_RS28445 96790031f5fb90024dfc7bdc035ea9f4 266 Pfam PF00175 Oxidoreductase NAD-binding domain 121 241 2.5E-9 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS28445 96790031f5fb90024dfc7bdc035ea9f4 266 SUPERFAMILY SSF63380 7 108 2.51E-21 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS05250 e6fdf296c16422feaa0379e1dcf35fd5 344 SUPERFAMILY SSF55347 134 302 1.8E-28 T 29-03-2018 CVS48_RS05250 e6fdf296c16422feaa0379e1dcf35fd5 344 Gene3D G3DSA:3.30.360.10 141 344 6.2E-38 T 29-03-2018 CVS48_RS05250 e6fdf296c16422feaa0379e1dcf35fd5 344 Gene3D G3DSA:3.40.50.720 1 140 1.0E-36 T 29-03-2018 CVS48_RS05250 e6fdf296c16422feaa0379e1dcf35fd5 344 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 123 6.0E-24 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CVS48_RS05250 e6fdf296c16422feaa0379e1dcf35fd5 344 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 145 247 4.9E-6 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CVS48_RS05250 e6fdf296c16422feaa0379e1dcf35fd5 344 SUPERFAMILY SSF51735 4 158 5.14E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS14370 fa6a870018269af36be0a5f1906bc50c 512 Pfam PF07690 Major Facilitator Superfamily 14 406 2.2E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS14370 fa6a870018269af36be0a5f1906bc50c 512 Gene3D G3DSA:1.20.1250.20 249 500 2.1E-26 T 29-03-2018 CVS48_RS14370 fa6a870018269af36be0a5f1906bc50c 512 SUPERFAMILY SSF103473 9 190 1.44E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS14370 fa6a870018269af36be0a5f1906bc50c 512 SUPERFAMILY SSF103473 245 416 1.44E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS14370 fa6a870018269af36be0a5f1906bc50c 512 SUPERFAMILY SSF103473 469 497 1.44E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS14370 fa6a870018269af36be0a5f1906bc50c 512 Gene3D G3DSA:1.20.1250.20 5 193 8.6E-33 T 29-03-2018 CVS48_RS14370 fa6a870018269af36be0a5f1906bc50c 512 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 10 492 5.2E-160 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CVS48_RS13920 a27e4b0ebb453a67b226bcf7b851f14c 397 SUPERFAMILY SSF89796 5 396 2.88E-128 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS13920 a27e4b0ebb453a67b226bcf7b851f14c 397 Gene3D G3DSA:3.40.50.10540 1 397 6.9E-137 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS13920 a27e4b0ebb453a67b226bcf7b851f14c 397 Pfam PF02515 CoA-transferase family III 6 373 8.9E-124 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS20760 8fa1ea7dc51674b3696c0f0817a89f3b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20760 8fa1ea7dc51674b3696c0f0817a89f3b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20760 8fa1ea7dc51674b3696c0f0817a89f3b 205 SUPERFAMILY SSF46689 3 76 3.94E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS20760 8fa1ea7dc51674b3696c0f0817a89f3b 205 SUPERFAMILY SSF48498 86 201 4.45E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS20760 8fa1ea7dc51674b3696c0f0817a89f3b 205 Gene3D G3DSA:1.10.10.60 8 67 3.2E-22 T 29-03-2018 CVS48_RS20760 8fa1ea7dc51674b3696c0f0817a89f3b 205 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 147 201 1.2E-19 T 29-03-2018 CVS48_RS20760 8fa1ea7dc51674b3696c0f0817a89f3b 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CVS48_RS20760 8fa1ea7dc51674b3696c0f0817a89f3b 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 6.9E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20760 8fa1ea7dc51674b3696c0f0817a89f3b 205 Gene3D G3DSA:1.10.357.10 68 205 1.1E-20 T 29-03-2018 CVS48_RS19950 2cb46d7c8bb5e3ef4d74a41ea05cd8c2 875 Pfam PF13476 AAA domain 5 301 4.4E-6 T 29-03-2018 CVS48_RS19950 2cb46d7c8bb5e3ef4d74a41ea05cd8c2 875 SUPERFAMILY SSF52540 151 167 4.43E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19950 2cb46d7c8bb5e3ef4d74a41ea05cd8c2 875 SUPERFAMILY SSF52540 768 859 4.43E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19950 2cb46d7c8bb5e3ef4d74a41ea05cd8c2 875 SUPERFAMILY SSF52540 1 116 4.43E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19950 2cb46d7c8bb5e3ef4d74a41ea05cd8c2 875 Gene3D G3DSA:3.40.50.300 1 869 1.5E-19 T 29-03-2018 CVS48_RS12785 fd010ad2ee6fe1a5e5a109558425da2b 191 Pfam PF02417 Chromate transporter 20 177 3.9E-29 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CVS48_RS27125 7efaa5600d6107d31b235dbf8a1a3e8a 208 SUPERFAMILY SSF102405 10 188 3.97E-57 T 29-03-2018 CVS48_RS27125 7efaa5600d6107d31b235dbf8a1a3e8a 208 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 17 189 4.4E-43 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CVS48_RS27125 7efaa5600d6107d31b235dbf8a1a3e8a 208 Gene3D G3DSA:3.40.50.450 1 205 2.2E-63 T 29-03-2018 CVS48_RS27125 7efaa5600d6107d31b235dbf8a1a3e8a 208 Pfam PF03641 Possible lysine decarboxylase 59 188 4.1E-33 T 29-03-2018 IPR031100 LOG family CVS48_RS14195 8691224a8f03ed2d1a7eb6df9bb8171f 263 Gene3D G3DSA:1.10.3720.10 5 253 7.2E-35 T 29-03-2018 CVS48_RS14195 8691224a8f03ed2d1a7eb6df9bb8171f 263 SUPERFAMILY SSF161098 3 248 2.06E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS14195 8691224a8f03ed2d1a7eb6df9bb8171f 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 247 5.7E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 2.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 2.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 2.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 SUPERFAMILY SSF53850 98 301 1.54E-37 T 29-03-2018 CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 71 2.0E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 Gene3D G3DSA:1.10.10.10 5 92 5.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 Pfam PF03466 LysR substrate binding domain 96 301 5.3E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 Gene3D G3DSA:3.40.190.10 188 272 3.3E-15 T 29-03-2018 CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 Gene3D G3DSA:3.40.190.10 96 187 2.5E-13 T 29-03-2018 CVS48_RS20225 38efd9c72ee6baee4757b8a6d1f906d7 324 SUPERFAMILY SSF46785 8 119 1.78E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18515 1e2deb24d1b56536ca36354da2c5b683 466 Gene3D G3DSA:3.40.50.1100 236 444 6.3E-19 T 29-03-2018 CVS48_RS18515 1e2deb24d1b56536ca36354da2c5b683 466 Gene3D G3DSA:3.40.50.1100 108 235 2.5E-25 T 29-03-2018 CVS48_RS18515 1e2deb24d1b56536ca36354da2c5b683 466 SUPERFAMILY SSF53686 52 400 5.9E-48 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS18515 1e2deb24d1b56536ca36354da2c5b683 466 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 73 403 1.2E-52 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS18515 1e2deb24d1b56536ca36354da2c5b683 466 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 13 440 3.5E-158 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CVS48_RS18515 1e2deb24d1b56536ca36354da2c5b683 466 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 459 197.143 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 3.5E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 Gene3D G3DSA:1.10.10.10 4 90 7.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 Gene3D G3DSA:3.40.190.10 92 189 4.2E-22 T 29-03-2018 CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 Pfam PF03466 LysR substrate binding domain 94 301 9.8E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 SUPERFAMILY SSF46785 8 112 1.09E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 3.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 3.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 3.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 SUPERFAMILY SSF53850 95 304 3.06E-36 T 29-03-2018 CVS48_RS22885 87aaff185c09b5d4c7b14cb1b170d77c 311 Gene3D G3DSA:3.40.190.10 190 272 9.0E-12 T 29-03-2018 CVS48_RS02225 4454475711267cdfaf1394bb3fa520e1 104 Gene3D G3DSA:3.30.1190.10 52 101 7.2E-7 T 29-03-2018 CVS48_RS02225 4454475711267cdfaf1394bb3fa520e1 104 Gene3D G3DSA:1.10.10.60 24 51 7.7E-7 T 29-03-2018 CVS48_RS02225 4454475711267cdfaf1394bb3fa520e1 104 SUPERFAMILY SSF47413 32 96 9.85E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS02225 4454475711267cdfaf1394bb3fa520e1 104 Pfam PF13744 Helix-turn-helix domain 17 86 2.8E-11 T 29-03-2018 CVS48_RS10100 e46ef5bf886a6143376dd4bed1fde5be 416 Pfam PF02515 CoA-transferase family III 21 384 2.6E-119 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS10100 e46ef5bf886a6143376dd4bed1fde5be 416 SUPERFAMILY SSF89796 19 407 5.36E-131 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS10100 e46ef5bf886a6143376dd4bed1fde5be 416 Gene3D G3DSA:3.40.50.10540 15 412 1.5E-141 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS11305 030569351b723a29a9b2a1d66cd1e5e8 244 Gene3D G3DSA:3.30.450.20 7 131 4.6E-23 T 29-03-2018 CVS48_RS11305 030569351b723a29a9b2a1d66cd1e5e8 244 SUPERFAMILY SSF55785 15 122 2.79E-24 T 29-03-2018 IPR000014 PAS domain CVS48_RS11305 030569351b723a29a9b2a1d66cd1e5e8 244 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 15 119 2.9E-19 T 29-03-2018 IPR000014 PAS domain CVS48_RS11305 030569351b723a29a9b2a1d66cd1e5e8 244 SMART SM00091 4 70 8.8E-7 T 29-03-2018 IPR000014 PAS domain CVS48_RS11305 030569351b723a29a9b2a1d66cd1e5e8 244 SUPERFAMILY SSF46894 143 223 1.45E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS11305 030569351b723a29a9b2a1d66cd1e5e8 244 Gene3D G3DSA:1.10.10.10 137 228 5.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11305 030569351b723a29a9b2a1d66cd1e5e8 244 Pfam PF08447 PAS fold 27 101 1.2E-14 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CVS48_RS11305 030569351b723a29a9b2a1d66cd1e5e8 244 SMART SM00862 147 222 9.9E-11 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS11305 030569351b723a29a9b2a1d66cd1e5e8 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 3.9E-13 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS27245 d007e387e9065996e586ed98172d5d2f 208 Pfam PF04199 Putative cyclase 6 151 4.2E-17 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CVS48_RS27245 d007e387e9065996e586ed98172d5d2f 208 TIGRFAM TIGR03035 trp_arylform: arylformamidase 3 208 2.7E-98 T 29-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CVS48_RS27245 d007e387e9065996e586ed98172d5d2f 208 Gene3D G3DSA:3.50.30.50 1 207 2.7E-45 T 29-03-2018 CVS48_RS27245 d007e387e9065996e586ed98172d5d2f 208 SUPERFAMILY SSF102198 2 206 1.96E-56 T 29-03-2018 CVS48_RS27245 d007e387e9065996e586ed98172d5d2f 208 Hamap MF_01969 Kynurenine formamidase [kynB]. 3 208 43.092 T 29-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CVS48_RS20315 400be2075f15a15213ad7b549b0e8463 336 PRINTS PR00069 Aldo-keto reductase signature 39 63 6.5E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS20315 400be2075f15a15213ad7b549b0e8463 336 PRINTS PR00069 Aldo-keto reductase signature 134 151 6.5E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS20315 400be2075f15a15213ad7b549b0e8463 336 PRINTS PR00069 Aldo-keto reductase signature 103 121 6.5E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS20315 400be2075f15a15213ad7b549b0e8463 336 SUPERFAMILY SSF51430 1 310 9.69E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS20315 400be2075f15a15213ad7b549b0e8463 336 Pfam PF00248 Aldo/keto reductase family 15 308 4.0E-62 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS20315 400be2075f15a15213ad7b549b0e8463 336 Gene3D G3DSA:3.20.20.100 3 311 1.7E-85 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS12715 ef17cac28b7081bb2620864a53328911 176 SUPERFAMILY SSF143422 1 136 1.44E-28 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CVS48_RS12715 ef17cac28b7081bb2620864a53328911 176 Gene3D G3DSA:3.30.70.1290 1 139 2.6E-32 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CVS48_RS12715 ef17cac28b7081bb2620864a53328911 176 SMART SM01321 9 131 2.4E-24 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CVS48_RS12715 ef17cac28b7081bb2620864a53328911 176 Pfam PF01797 Transposase IS200 like 32 130 9.2E-7 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 PRINTS PR00045 Sigma-54 factor signature 181 198 6.9E-27 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 PRINTS PR00045 Sigma-54 factor signature 377 389 6.9E-27 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 PRINTS PR00045 Sigma-54 factor signature 451 469 6.9E-27 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 PRINTS PR00045 Sigma-54 factor signature 393 404 6.9E-27 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 456 463 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 18 475 8.0E-133 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 365 384 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 12 55 6.6E-16 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 Pfam PF04963 Sigma-54 factor, core binding domain 108 305 7.9E-52 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 Pfam PF04552 Sigma-54, DNA binding domain 320 475 1.7E-62 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 PIRSF PIRSF000774 7 478 2.9E-147 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05390 49c2bfc3e013daa2afcc95f04f58d45d 481 Gene3D G3DSA:1.10.10.10 323 414 7.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 444 465 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 227 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 105 129 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 329 350 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 366 384 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 31 56 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 179 197 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 305 320 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 259 280 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 78 101 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 PRINTS PR01165 Cytochrome c oxidase subunit I signature 394 413 4.7E-81 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 SUPERFAMILY SSF81452 584 820 8.11E-12 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 41 487 2.0E-134 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 261 315 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 SUPERFAMILY SSF81442 30 527 6.54E-146 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 Gene3D G3DSA:1.20.210.10 29 536 2.4E-156 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18730 234585d3ac04a5a2aa96e455d2a8939c 840 Gene3D G3DSA:1.20.120.80 655 832 7.6E-17 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 371 8.7E-22 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 SUPERFAMILY SSF53738 161 261 7.46E-29 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 16 129 6.4E-32 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 173 259 8.3E-24 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 SUPERFAMILY SSF55957 372 466 8.37E-17 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 384 455 1.1E-8 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 SUPERFAMILY SSF53738 13 139 1.14E-36 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 105 114 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 5.0E-23 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 104 118 5.0E-23 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 5.0E-23 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 210 223 5.0E-23 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 Gene3D G3DSA:3.40.120.10 267 367 1.8E-25 T 29-03-2018 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 Gene3D G3DSA:3.40.120.10 13 143 9.9E-33 T 29-03-2018 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 Gene3D G3DSA:3.30.310.50 368 466 3.4E-12 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 SUPERFAMILY SSF53738 263 359 1.14E-31 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CVS48_RS23735 e1a31732be822956918e59082378cf9b 467 Gene3D G3DSA:3.40.120.10 159 266 8.6E-31 T 29-03-2018 CVS48_RS12645 41d70cceb4dc76d2f9c0721cc6330d14 375 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 49 362 8.8E-136 T 29-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC CVS48_RS12645 41d70cceb4dc76d2f9c0721cc6330d14 375 Gene3D G3DSA:1.10.3470.10 51 366 1.6E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS12645 41d70cceb4dc76d2f9c0721cc6330d14 375 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 351 8.4E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS02020 9d72358e8c96fcdc94334d0fb8db0506 346 Gene3D G3DSA:3.90.1200.10 99 344 2.1E-34 T 29-03-2018 CVS48_RS02020 9d72358e8c96fcdc94334d0fb8db0506 346 Pfam PF01636 Phosphotransferase enzyme family 30 258 6.6E-36 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CVS48_RS02020 9d72358e8c96fcdc94334d0fb8db0506 346 Gene3D G3DSA:3.30.200.20 5 98 3.6E-31 T 29-03-2018 CVS48_RS02020 9d72358e8c96fcdc94334d0fb8db0506 346 SUPERFAMILY SSF56112 11 325 1.2E-48 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 Gene3D G3DSA:4.10.860.10 181 243 7.1E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 SUPERFAMILY SSF82771 17 100 9.02E-22 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 SUPERFAMILY SSF47781 523 608 2.1E-18 T 29-03-2018 IPR010994 RuvA domain 2-like CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 SMART SM00465 17 98 2.9E-17 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 Gene3D G3DSA:1.10.150.20 554 609 6.7E-12 T 29-03-2018 CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 7 588 1.8E-168 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 Gene3D G3DSA:3.40.1440.10 4 101 3.5E-22 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 606 27.08 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 Pfam PF02151 UvrB/uvrC motif 203 235 6.7E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 SUPERFAMILY SSF46600 190 242 5.36E-12 T 29-03-2018 IPR001943 UVR domain GO:0005515 CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 Pfam PF01541 GIY-YIG catalytic domain 19 93 4.5E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 394 541 1.3E-45 T 29-03-2018 IPR001162 UvrC family homology region CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 Pfam PF14520 Helix-hairpin-helix domain 556 608 1.6E-8 T 29-03-2018 CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 SMART SM00278 587 606 0.78 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS23245 1e57890b033da3c19a69e8fb2add6b01 609 SMART SM00278 555 574 15.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS18915 7842d242c638236fc2cf734ac1c90349 418 PIRSF PIRSF004810 9 418 6.0E-118 T 29-03-2018 IPR014047 Chromate transporter, long chain CVS48_RS18915 7842d242c638236fc2cf734ac1c90349 418 Pfam PF02417 Chromate transporter 29 194 3.5E-32 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CVS48_RS18915 7842d242c638236fc2cf734ac1c90349 418 Pfam PF02417 Chromate transporter 249 411 1.1E-30 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CVS48_RS18915 7842d242c638236fc2cf734ac1c90349 418 TIGRFAM TIGR00937 2A51: chromate efflux transporter 35 411 8.2E-97 T 29-03-2018 IPR014047 Chromate transporter, long chain CVS48_RS09650 edaa6b78d28c667872493ad8a9157903 278 Gene3D G3DSA:3.40.50.1820 12 271 1.1E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS09650 edaa6b78d28c667872493ad8a9157903 278 SUPERFAMILY SSF53474 12 274 4.82E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS09650 edaa6b78d28c667872493ad8a9157903 278 Pfam PF00561 alpha/beta hydrolase fold 37 261 8.2E-24 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS00940 76e50bafdd230fa75ddb1fe8555a8f21 146 PIRSF PIRSF002070 1 146 4.9E-27 T 29-03-2018 CVS48_RS00940 76e50bafdd230fa75ddb1fe8555a8f21 146 Pfam PF00436 Single-strand binding protein family 7 109 1.9E-12 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CVS48_RS00940 76e50bafdd230fa75ddb1fe8555a8f21 146 Gene3D G3DSA:2.40.50.140 1 118 3.6E-23 T 29-03-2018 CVS48_RS00940 76e50bafdd230fa75ddb1fe8555a8f21 146 SUPERFAMILY SSF50249 2 134 1.75E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS03410 f49cd737da7dfa300ce90d96b2762a14 546 Gene3D G3DSA:2.30.38.10 363 442 6.1E-14 T 29-03-2018 CVS48_RS03410 f49cd737da7dfa300ce90d96b2762a14 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 458 536 1.4E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS03410 f49cd737da7dfa300ce90d96b2762a14 546 Gene3D G3DSA:3.40.50.980 213 362 1.1E-40 T 29-03-2018 CVS48_RS03410 f49cd737da7dfa300ce90d96b2762a14 546 SUPERFAMILY SSF56801 29 545 6.8E-136 T 29-03-2018 CVS48_RS03410 f49cd737da7dfa300ce90d96b2762a14 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 208 219 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS03410 f49cd737da7dfa300ce90d96b2762a14 546 Gene3D G3DSA:3.30.300.30 445 546 7.0E-28 T 29-03-2018 CVS48_RS03410 f49cd737da7dfa300ce90d96b2762a14 546 Pfam PF00501 AMP-binding enzyme 51 449 2.1E-77 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS03410 f49cd737da7dfa300ce90d96b2762a14 546 Gene3D G3DSA:3.40.50.980 37 212 2.2E-37 T 29-03-2018 CVS48_RS11350 0b2834fd091aac885604c58871a0fedd 270 Gene3D G3DSA:3.40.830.10 1 269 3.1E-39 T 29-03-2018 CVS48_RS11350 0b2834fd091aac885604c58871a0fedd 270 SUPERFAMILY SSF53213 5 267 3.53E-40 T 29-03-2018 CVS48_RS11350 0b2834fd091aac885604c58871a0fedd 270 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 24 263 2.9E-20 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CVS48_RS22895 d4253853bea14061cf400a132b3196e0 423 SUPERFAMILY SSF53474 6 412 6.14E-91 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS22895 d4253853bea14061cf400a132b3196e0 423 Pfam PF00135 Carboxylesterase family 9 312 1.1E-73 T 29-03-2018 IPR002018 Carboxylesterase, type B CVS48_RS22895 d4253853bea14061cf400a132b3196e0 423 Gene3D G3DSA:3.40.50.1820 317 420 4.3E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS22895 d4253853bea14061cf400a132b3196e0 423 Gene3D G3DSA:3.40.50.1820 2 316 1.7E-91 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11730 c015f2e7dce64937f3f880a125bd4e6f 255 Pfam PF13460 NAD(P)H-binding 7 172 2.4E-9 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11730 c015f2e7dce64937f3f880a125bd4e6f 255 Gene3D G3DSA:3.40.50.720 1 234 7.5E-14 T 29-03-2018 CVS48_RS11730 c015f2e7dce64937f3f880a125bd4e6f 255 SUPERFAMILY SSF51735 1 213 1.69E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 241 254 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 Gene3D G3DSA:3.20.20.10 47 280 8.3E-62 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 43 384 2.6E-25 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 20 426 4.0E-154 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 28 427 40.891 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 SUPERFAMILY SSF50621 273 427 6.91E-52 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 177 186 2.7E-29 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 88 105 2.7E-29 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 394 416 2.7E-29 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 314 332 2.7E-29 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 286 305 2.5E-24 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 90 102 2.5E-24 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 70 88 2.5E-24 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 203 216 2.5E-24 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 384 397 2.5E-24 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 49 295 1.0E-68 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 Gene3D G3DSA:2.40.37.10 281 428 8.7E-47 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CVS48_RS06740 d9a55dfd07e6bd82401b13e9915cbad4 430 SUPERFAMILY SSF51419 39 298 3.2E-79 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS01930 de08553663f3d5e65d5e0ff5a51e21d5 410 Gene3D G3DSA:3.40.50.10540 1 407 1.5E-154 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS01930 de08553663f3d5e65d5e0ff5a51e21d5 410 Pfam PF02515 CoA-transferase family III 7 385 4.3E-130 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS01930 de08553663f3d5e65d5e0ff5a51e21d5 410 SUPERFAMILY SSF89796 5 405 2.88E-143 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS23480 2bd93fa096916c7062daf5ba2f2a4379 199 SUPERFAMILY SSF53955 6 161 1.59E-24 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS23480 2bd93fa096916c7062daf5ba2f2a4379 199 Gene3D G3DSA:1.10.530.10 33 192 5.8E-18 T 29-03-2018 CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 ProSitePatterns PS01175 Ribonuclease II family signature. 576 600 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 Pfam PF00575 S1 RNA binding domain 668 748 2.5E-10 T 29-03-2018 IPR003029 S1 domain GO:0003676 CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 SUPERFAMILY SSF50249 147 246 4.11E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 90 751 5.7E-205 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 SUPERFAMILY SSF50249 670 750 3.06E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 SMART SM00357 96 154 2.3E-12 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 SUPERFAMILY SSF50249 77 156 2.2E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 SMART SM00955 269 609 1.1E-177 T 29-03-2018 CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 Pfam PF00773 RNB domain 269 608 5.4E-100 T 29-03-2018 CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 SMART SM00316 668 751 1.6E-12 T 29-03-2018 IPR022967 RNA-binding domain, S1 CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 TIGRFAM TIGR02063 RNase_R: ribonuclease R 29 751 2.7E-245 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 Gene3D G3DSA:2.40.50.140 667 752 1.2E-19 T 29-03-2018 CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 Gene3D G3DSA:1.10.10.10 6 89 1.9E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 SUPERFAMILY SSF50249 229 667 2.23E-134 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 Pfam PF08206 Ribonuclease B OB domain 97 153 2.0E-19 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CVS48_RS26440 9dc57f8712b52ab218bf26d5b7aaaf4b 821 Hamap MF_01895 Ribonuclease R [rnr]. 48 751 54.394 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 Pfam PF07729 FCD domain 87 209 1.9E-16 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 SMART SM00895 87 211 1.2E-12 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 Gene3D G3DSA:1.20.120.530 87 227 1.9E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 69 6.4E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 SUPERFAMILY SSF46785 10 81 5.09E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 4.0E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 4.0E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 SMART SM00345 20 77 1.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 Gene3D G3DSA:1.10.10.10 1 86 2.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13575 914002eb60cc4173fe171f7ad6a30a06 236 SUPERFAMILY SSF48008 83 218 8.89E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS14270 383047cc8e7d50691aaa5f302e5efcda 505 SUPERFAMILY SSF100950 4 222 1.99E-71 T 29-03-2018 CVS48_RS14270 383047cc8e7d50691aaa5f302e5efcda 505 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 13 494 1.5E-228 T 29-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 CVS48_RS14270 383047cc8e7d50691aaa5f302e5efcda 505 SUPERFAMILY SSF100950 227 494 2.18E-77 T 29-03-2018 CVS48_RS14270 383047cc8e7d50691aaa5f302e5efcda 505 Gene3D G3DSA:3.40.1080.10 13 237 4.9E-38 T 29-03-2018 CVS48_RS14270 383047cc8e7d50691aaa5f302e5efcda 505 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 322 463 8.6E-42 T 29-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CVS48_RS14270 383047cc8e7d50691aaa5f302e5efcda 505 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 13 215 6.5E-30 T 29-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 CVS48_RS14270 383047cc8e7d50691aaa5f302e5efcda 505 Gene3D G3DSA:3.40.1080.10 238 499 3.6E-58 T 29-03-2018 CVS48_RS02765 f7a1f23767b9d3a6c2bc966bab9b6e46 216 Pfam PF07729 FCD domain 82 195 6.5E-15 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS02765 f7a1f23767b9d3a6c2bc966bab9b6e46 216 SMART SM00895 82 205 5.5E-7 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS02765 f7a1f23767b9d3a6c2bc966bab9b6e46 216 SUPERFAMILY SSF48008 79 205 2.33E-12 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS02765 f7a1f23767b9d3a6c2bc966bab9b6e46 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 72 1.1E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS02765 f7a1f23767b9d3a6c2bc966bab9b6e46 216 Gene3D G3DSA:1.20.120.530 68 215 2.7E-18 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS02765 f7a1f23767b9d3a6c2bc966bab9b6e46 216 SUPERFAMILY SSF46785 5 76 1.23E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02765 f7a1f23767b9d3a6c2bc966bab9b6e46 216 SMART SM00345 14 72 1.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS02765 f7a1f23767b9d3a6c2bc966bab9b6e46 216 Gene3D G3DSA:1.10.10.10 1 67 2.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05305 8dc1834f6b0db1f8f403b01291cdcd72 407 Gene3D G3DSA:3.40.640.10 42 281 1.0E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS05305 8dc1834f6b0db1f8f403b01291cdcd72 407 Pfam PF00266 Aminotransferase class-V 33 394 3.8E-52 T 29-03-2018 IPR000192 Aminotransferase class V domain CVS48_RS05305 8dc1834f6b0db1f8f403b01291cdcd72 407 SUPERFAMILY SSF53383 15 402 1.28E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS05305 8dc1834f6b0db1f8f403b01291cdcd72 407 Gene3D G3DSA:3.90.1150.10 282 401 3.5E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS19240 1e3674947afe3b746889580def16e601 390 SUPERFAMILY SSF50952 43 385 9.94E-52 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CVS48_RS19240 1e3674947afe3b746889580def16e601 390 Gene3D G3DSA:2.120.10.30 289 379 6.9E-17 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS19240 1e3674947afe3b746889580def16e601 390 Gene3D G3DSA:2.120.10.30 27 288 6.6E-58 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS19240 1e3674947afe3b746889580def16e601 390 Pfam PF07995 Glucose / Sorbosone dehydrogenase 52 382 6.3E-141 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CVS48_RS06970 27f235ae0dfd237228a53f69f1c6e03b 189 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 9 140 4.4E-29 T 29-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G CVS48_RS06970 27f235ae0dfd237228a53f69f1c6e03b 189 SUPERFAMILY SSF55961 1 145 1.57E-27 T 29-03-2018 CVS48_RS06970 27f235ae0dfd237228a53f69f1c6e03b 189 Gene3D G3DSA:3.30.530.20 1 154 8.1E-14 T 29-03-2018 IPR023393 START-like domain CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 294 29.083 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 96 280 9.8E-49 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 SUPERFAMILY SSF82866 73 294 4.58E-39 T 29-03-2018 CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 Pfam PF02355 Protein export membrane protein 108 291 6.4E-63 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 Pfam PF07549 SecD/SecF GG Motif 32 59 1.7E-8 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 5.1E-27 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 5.1E-27 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 5.1E-27 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 PRINTS PR01755 Bacterial translocase SecF protein signature 231 246 5.1E-27 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 Gene3D G3DSA:1.20.1640.10 87 302 1.1E-31 T 29-03-2018 CVS48_RS12995 824f6a5847b690dc7b57f2a2e0446ae9 311 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 283 4.0E-75 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CVS48_RS06835 18a33ac4177cbde0fae639e236bd9e5d 242 Pfam PF08241 Methyltransferase domain 47 141 3.5E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CVS48_RS06835 18a33ac4177cbde0fae639e236bd9e5d 242 SUPERFAMILY SSF53335 3 216 8.2E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS06835 18a33ac4177cbde0fae639e236bd9e5d 242 Gene3D G3DSA:3.40.50.150 25 242 3.0E-46 T 29-03-2018 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 21 267 31.516 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 PIRSF PIRSF000513 14 271 2.5E-90 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 71 79 4.6E-37 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 40 61 4.6E-37 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 171 188 4.6E-37 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 27 34 4.6E-37 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 97 114 4.6E-37 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 127 141 4.6E-37 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 21 263 8.6E-81 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 Gene3D G3DSA:3.40.1190.20 1 273 1.7E-54 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 Pfam PF02110 Hydroxyethylthiazole kinase family 21 262 2.0E-78 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS21735 47ac8c37a3a8cf47340efb4228a409f0 273 SUPERFAMILY SSF53613 16 263 1.08E-60 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS20820 280e6e90e664ebfba8275b3e315650f1 522 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 56 499 5.3E-136 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CVS48_RS20820 280e6e90e664ebfba8275b3e315650f1 522 ProSitePatterns PS01303 BCCT family of transporters signature. 312 321 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CVS48_RS20820 280e6e90e664ebfba8275b3e315650f1 522 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 14 498 2.1E-119 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 291 3.7E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 SUPERFAMILY SSF56014 638 813 3.93E-50 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 Gene3D G3DSA:3.50.50.60 1 132 4.3E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 13 805 0.0 T 29-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 Gene3D G3DSA:3.90.480.10 392 634 1.9E-7 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 7.5E-17 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 7.5E-17 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 7.5E-17 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 7.5E-17 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 7.5E-17 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 Gene3D G3DSA:3.30.413.10 636 840 1.0E-36 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 4.3E-10 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 4.3E-10 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 4.3E-10 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 281 288 4.3E-10 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 684 700 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 Gene3D G3DSA:3.40.50.720 133 314 2.7E-28 T 29-03-2018 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00397 Sirohaem Fe-binding site signature 641 659 6.6E-7 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PRINTS PR00397 Sirohaem Fe-binding site signature 684 702 6.6E-7 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 SUPERFAMILY SSF55124 511 646 1.96E-25 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 SUPERFAMILY SSF51905 11 196 2.74E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 637 758 1.6E-18 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 Pfam PF04324 BFD-like [2Fe-2S] binding domain 427 475 1.6E-8 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 SUPERFAMILY SSF51905 155 313 2.96E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 565 627 2.4E-11 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CVS48_RS21370 253469c305c994ec7e742f49a2c91fb5 857 PIRSF PIRSF037149 5 840 0.0 T 29-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CVS48_RS10750 acfc60a810a97df01cfeb821af73bdff 263 SUPERFAMILY SSF48317 19 229 9.37E-13 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS10750 acfc60a810a97df01cfeb821af73bdff 263 Gene3D G3DSA:1.20.144.10 8 232 5.1E-9 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS10750 acfc60a810a97df01cfeb821af73bdff 263 Pfam PF01569 PAP2 superfamily 105 229 1.2E-14 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS23710 9bbe2e67503971070088411e805b5ecd 284 Gene3D G3DSA:3.40.190.80 164 280 9.3E-16 T 29-03-2018 CVS48_RS23710 9bbe2e67503971070088411e805b5ecd 284 Pfam PF00459 Inositol monophosphatase family 11 262 3.3E-43 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS23710 9bbe2e67503971070088411e805b5ecd 284 SUPERFAMILY SSF56655 7 274 9.82E-59 T 29-03-2018 CVS48_RS23710 9bbe2e67503971070088411e805b5ecd 284 Gene3D G3DSA:3.30.540.10 1 159 3.6E-35 T 29-03-2018 CVS48_RS23710 9bbe2e67503971070088411e805b5ecd 284 PRINTS PR00377 Inositol monophosphatase superfamily signature 222 246 3.6E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS23710 9bbe2e67503971070088411e805b5ecd 284 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 3.6E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS23710 9bbe2e67503971070088411e805b5ecd 284 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 3.6E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS23710 9bbe2e67503971070088411e805b5ecd 284 PRINTS PR00377 Inositol monophosphatase superfamily signature 67 83 3.6E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CVS48_RS13890 2807f941890d880365cb74ceeb207556 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 326 3.8E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13890 2807f941890d880365cb74ceeb207556 338 SUPERFAMILY SSF161098 46 323 9.68E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13890 2807f941890d880365cb74ceeb207556 338 Gene3D G3DSA:1.10.3720.10 27 324 1.4E-31 T 29-03-2018 CVS48_RS13890 2807f941890d880365cb74ceeb207556 338 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 37 329 7.5E-91 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CVS48_RS24025 5b2861398aa78a25a54b44fc2e2d412f 352 SUPERFAMILY SSF52821 90 127 1.06E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS24025 5b2861398aa78a25a54b44fc2e2d412f 352 SUPERFAMILY SSF52821 17 63 1.06E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS24025 5b2861398aa78a25a54b44fc2e2d412f 352 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 14 318 7.7E-103 T 29-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 CVS48_RS24025 5b2861398aa78a25a54b44fc2e2d412f 352 Gene3D G3DSA:3.40.250.10 6 124 5.0E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS24025 5b2861398aa78a25a54b44fc2e2d412f 352 SMART SM00450 1 130 2.5E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS24025 5b2861398aa78a25a54b44fc2e2d412f 352 Gene3D G3DSA:3.40.50.300 153 351 2.2E-8 T 29-03-2018 CVS48_RS24025 5b2861398aa78a25a54b44fc2e2d412f 352 SUPERFAMILY SSF52540 140 280 1.27E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS24025 5b2861398aa78a25a54b44fc2e2d412f 352 Pfam PF00581 Rhodanese-like domain 7 125 4.2E-8 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS24025 5b2861398aa78a25a54b44fc2e2d412f 352 Gene3D G3DSA:3.40.1140.10 125 152 0.0016 T 29-03-2018 CVS48_RS13705 3693b93ba82ab9889472b05f61594d7f 403 Gene3D G3DSA:1.20.1250.20 2 199 6.4E-26 T 29-03-2018 CVS48_RS13705 3693b93ba82ab9889472b05f61594d7f 403 Pfam PF07690 Major Facilitator Superfamily 18 342 4.1E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS13705 3693b93ba82ab9889472b05f61594d7f 403 Gene3D G3DSA:1.20.1250.20 200 398 2.9E-27 T 29-03-2018 CVS48_RS13705 3693b93ba82ab9889472b05f61594d7f 403 SUPERFAMILY SSF103473 8 392 1.2E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS19395 1316fdbeeed6a9a2bedfaf5448ad8b07 167 ProSitePatterns PS00819 Dps protein family signature 2. 75 89 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CVS48_RS19395 1316fdbeeed6a9a2bedfaf5448ad8b07 167 SUPERFAMILY SSF47240 16 167 4.43E-48 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS19395 1316fdbeeed6a9a2bedfaf5448ad8b07 167 PIRSF PIRSF005900 6 167 4.4E-44 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CVS48_RS19395 1316fdbeeed6a9a2bedfaf5448ad8b07 167 Pfam PF00210 Ferritin-like domain 31 167 4.3E-32 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CVS48_RS19395 1316fdbeeed6a9a2bedfaf5448ad8b07 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 144 162 1.3E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CVS48_RS19395 1316fdbeeed6a9a2bedfaf5448ad8b07 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 73 89 1.3E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CVS48_RS19395 1316fdbeeed6a9a2bedfaf5448ad8b07 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 49 65 1.3E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CVS48_RS19395 1316fdbeeed6a9a2bedfaf5448ad8b07 167 Gene3D G3DSA:1.20.1260.10 9 167 5.2E-49 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS21395 59c49d748b330e1ab8a24645d4ea31b4 421 SMART SM01012 360 415 2.3E-18 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CVS48_RS21395 59c49d748b330e1ab8a24645d4ea31b4 421 Pfam PF08376 Nitrate and nitrite sensing 40 282 5.0E-40 T 29-03-2018 IPR013587 Nitrate/nitrite sensing protein CVS48_RS21395 59c49d748b330e1ab8a24645d4ea31b4 421 SUPERFAMILY SSF52172 342 415 6.46E-13 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS21395 59c49d748b330e1ab8a24645d4ea31b4 421 Pfam PF03861 ANTAR domain 364 415 5.3E-18 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CVS48_RS21395 59c49d748b330e1ab8a24645d4ea31b4 421 Gene3D G3DSA:1.10.10.10 364 417 7.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 SMART SM00387 351 463 4.1E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 Gene3D G3DSA:1.10.287.130 235 304 1.3E-14 T 29-03-2018 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 SUPERFAMILY SSF47384 228 306 6.08E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 Gene3D G3DSA:3.30.565.10 312 467 7.7E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 Pfam PF00672 HAMP domain 189 240 1.2E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 307 1.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 SMART SM00304 189 244 1.9E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 416 2.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 2.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 2.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 2.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 SUPERFAMILY SSF55874 302 462 6.29E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 SUPERFAMILY SSF158472 189 242 7.72E-11 T 29-03-2018 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 SMART SM00388 245 308 3.9E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS21775 a45d383cc1ce16a84fa6c7d757796a99 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 462 1.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS29015 dfe6899106ee43b253cb71a2732c21dc 343 Pfam PF16220 Domain of unknown function (DUF4880) 17 56 7.0E-10 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS29015 dfe6899106ee43b253cb71a2732c21dc 343 PIRSF PIRSF018266 8 339 9.4E-68 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS29015 dfe6899106ee43b253cb71a2732c21dc 343 Pfam PF04773 FecR protein 130 222 1.3E-12 T 29-03-2018 IPR006860 FecR protein CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 Hamap MF_01151 Protein GrpE [grpE]. 8 182 19.262 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 Gene3D G3DSA:3.90.20.20 22 125 2.8E-25 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 SUPERFAMILY SSF51064 131 183 1.96E-15 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 PRINTS PR00773 GrpE protein signature 135 150 4.2E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 PRINTS PR00773 GrpE protein signature 82 97 4.2E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 PRINTS PR00773 GrpE protein signature 161 180 4.2E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 PRINTS PR00773 GrpE protein signature 54 70 4.2E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 Pfam PF01025 GrpE 24 181 7.2E-46 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 ProSitePatterns PS01071 grpE protein signature. 138 180 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 SUPERFAMILY SSF58014 31 124 1.05E-23 T 29-03-2018 CVS48_RS00425 4eb757c7a1b0c12c8e1588295a0f613c 185 Gene3D G3DSA:2.30.22.10 127 185 4.4E-19 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CVS48_RS15270 1f5854a1a06c29ed26b5cdf5a9044e7f 248 Pfam PF01925 Sulfite exporter TauE/SafE 10 237 8.8E-25 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CVS48_RS25350 a93bf3cb53fe5b0a7562bc1748c5d415 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 292 2.4E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS25350 a93bf3cb53fe5b0a7562bc1748c5d415 293 Gene3D G3DSA:1.10.3720.10 14 281 1.9E-38 T 29-03-2018 CVS48_RS25350 a93bf3cb53fe5b0a7562bc1748c5d415 293 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 56 9.3E-9 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS25350 a93bf3cb53fe5b0a7562bc1748c5d415 293 SUPERFAMILY SSF161098 87 276 1.28E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09640 cfe267244bf01a4f7aeccd4f76f1071f 228 SUPERFAMILY SSF52499 20 216 5.49E-52 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS09640 cfe267244bf01a4f7aeccd4f76f1071f 228 Gene3D G3DSA:3.40.50.850 35 222 6.5E-47 T 29-03-2018 CVS48_RS09640 cfe267244bf01a4f7aeccd4f76f1071f 228 Pfam PF00857 Isochorismatase family 37 207 1.8E-42 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS13710 8ab1d5953656b1a17c7247888726e5b7 892 SUPERFAMILY SSF52540 229 569 3.72E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13710 8ab1d5953656b1a17c7247888726e5b7 892 Pfam PF12705 PD-(D/E)XK nuclease superfamily 613 863 2.5E-18 T 29-03-2018 CVS48_RS13710 8ab1d5953656b1a17c7247888726e5b7 892 TIGRFAM TIGR03623 TIGR03623: probable DNA repair protein 28 885 4.0E-241 T 29-03-2018 IPR019925 DNA repair protein, predicted CVS48_RS13710 8ab1d5953656b1a17c7247888726e5b7 892 Gene3D G3DSA:3.90.320.10 437 814 5.0E-15 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 13 361 2.9E-100 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 Gene3D G3DSA:3.40.140.10 4 133 4.5E-33 T 29-03-2018 CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 SUPERFAMILY SSF53597 154 363 2.29E-54 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 SUPERFAMILY SSF53927 9 153 2.13E-46 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 108 2.1E-18 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 155 365 1.9E-50 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 Gene3D G3DSA:3.40.430.10 134 368 1.8E-64 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 97 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 Pfam PF01872 RibD C-terminal domain 156 335 5.0E-41 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CVS48_RS02950 9a31fc809cc6da42f6980757083d06a9 384 PIRSF PIRSF006769 5 369 2.2E-112 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CVS48_RS02850 fc317d44b5b90b2586f5002f8f35efb3 273 SUPERFAMILY SSF56281 17 272 1.35E-68 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS02850 fc317d44b5b90b2586f5002f8f35efb3 273 Gene3D G3DSA:3.60.15.10 10 272 1.2E-68 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS02850 fc317d44b5b90b2586f5002f8f35efb3 273 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 15 272 42.894 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CVS48_RS02850 fc317d44b5b90b2586f5002f8f35efb3 273 SMART SM00849 25 184 4.3E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS02850 fc317d44b5b90b2586f5002f8f35efb3 273 Pfam PF00753 Metallo-beta-lactamase superfamily 27 184 3.4E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS02850 fc317d44b5b90b2586f5002f8f35efb3 273 PIRSF PIRSF005457 11 272 6.5E-97 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CVS48_RS02850 fc317d44b5b90b2586f5002f8f35efb3 273 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 18 272 1.6E-100 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CVS48_RS02850 fc317d44b5b90b2586f5002f8f35efb3 273 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 185 272 1.4E-26 T 29-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 SUPERFAMILY SSF51126 748 909 4.39E-18 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 SUPERFAMILY SSF103515 1436 1715 2.35E-61 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 SUPERFAMILY SSF103515 1380 1407 2.35E-61 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 368 394 4.9E-8 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 689 716 1.0E-10 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1153 1183 2.1E-6 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 782 813 6.0E-12 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1062 1093 1.9E-8 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Gene3D G3DSA:2.160.20.20 501 766 0.0023 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Gene3D G3DSA:2.160.20.20 767 919 6.4E-5 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Gene3D G3DSA:2.160.20.20 1107 1265 0.0016 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Gene3D G3DSA:2.160.20.20 947 1106 0.046 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Pfam PF03797 Autotransporter beta-domain 1443 1695 4.5E-55 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 SMART SM00869 1440 1705 1.2E-48 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 SUPERFAMILY SSF51126 407 763 4.08E-15 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 SUPERFAMILY SSF51126 246 491 5.02E-10 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Gene3D G3DSA:2.40.128.130 1371 1715 1.2E-55 T 29-03-2018 CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Pfam PF12951 Passenger-associated-transport-repeat 1153 1183 1.1E-5 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Pfam PF12951 Passenger-associated-transport-repeat 1064 1092 3.8E-8 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Pfam PF12951 Passenger-associated-transport-repeat 370 393 2.0E-6 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Pfam PF12951 Passenger-associated-transport-repeat 436 457 0.076 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Pfam PF12951 Passenger-associated-transport-repeat 783 812 4.3E-9 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 Pfam PF12951 Passenger-associated-transport-repeat 689 716 3.4E-10 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 SUPERFAMILY SSF51126 899 928 4.71E-17 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 SUPERFAMILY SSF51126 972 1303 4.71E-17 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS16475 67b69c89ded4e102b9ef56e0d3602fd1 1715 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1222 1715 4.4E-39 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 SUPERFAMILY SSF46785 13 91 5.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 Gene3D G3DSA:3.40.190.10 188 271 9.1E-15 T 29-03-2018 CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 Gene3D G3DSA:1.10.10.10 5 97 2.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 Pfam PF03466 LysR substrate binding domain 100 296 3.3E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 74 4.2E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 2.0E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 2.0E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 2.0E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 SUPERFAMILY SSF53850 103 303 1.88E-32 T 29-03-2018 CVS48_RS25375 c5fb6c36ab71c161b63c63a21225de85 315 Gene3D G3DSA:3.40.190.10 101 187 1.0E-19 T 29-03-2018 CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 2.0E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 2.0E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 2.0E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 Gene3D G3DSA:3.40.50.720 4 172 5.4E-45 T 29-03-2018 CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 204 1.9E-7 T 29-03-2018 CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 Gene3D G3DSA:3.40.50.720 173 255 5.4E-14 T 29-03-2018 CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 Pfam PF00106 short chain dehydrogenase 8 196 6.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01920 5ba34e5a6decee2883a304aacfb50313 304 SUPERFAMILY SSF51735 6 261 3.61E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS18410 15503278186b54fcaad4e423374da056 132 SUPERFAMILY SSF50346 13 132 2.16E-28 T 29-03-2018 IPR011033 PRC-barrel-like CVS48_RS18410 15503278186b54fcaad4e423374da056 132 Gene3D G3DSA:3.90.50.10 11 132 1.3E-34 T 29-03-2018 CVS48_RS18410 15503278186b54fcaad4e423374da056 132 Pfam PF05239 PRC-barrel domain 21 98 1.4E-17 T 29-03-2018 IPR027275 PRC-barrel domain CVS48_RS26355 da8364c66a7b97b66062f02ef37afcef 187 Gene3D G3DSA:3.30.70.100 99 186 6.5E-8 T 29-03-2018 CVS48_RS03460 0e2ff5a97f4fd883964463bab42f5e61 234 Pfam PF00005 ABC transporter 19 162 8.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS03460 0e2ff5a97f4fd883964463bab42f5e61 234 Gene3D G3DSA:3.40.50.300 1 232 1.0E-50 T 29-03-2018 CVS48_RS03460 0e2ff5a97f4fd883964463bab42f5e61 234 SMART SM00382 26 211 1.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03460 0e2ff5a97f4fd883964463bab42f5e61 234 SUPERFAMILY SSF52540 2 231 3.37E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03460 0e2ff5a97f4fd883964463bab42f5e61 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS12510 f8344386818c2e4255c6eb008b085504 209 Pfam PF03006 Haemolysin-III related 4 197 2.8E-34 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CVS48_RS23005 7b89241095c2efff45bca1ff507b5b31 451 Gene3D G3DSA:1.20.1250.20 223 444 1.9E-14 T 29-03-2018 CVS48_RS23005 7b89241095c2efff45bca1ff507b5b31 451 Pfam PF07690 Major Facilitator Superfamily 25 389 1.3E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS23005 7b89241095c2efff45bca1ff507b5b31 451 SUPERFAMILY SSF103473 12 435 2.09E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS23005 7b89241095c2efff45bca1ff507b5b31 451 Gene3D G3DSA:1.20.1250.20 9 222 7.8E-35 T 29-03-2018 CVS48_RS26120 971e12a1b1a9226fc6496b89f4d84121 591 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS26120 971e12a1b1a9226fc6496b89f4d84121 591 Gene3D G3DSA:3.40.50.300 336 591 6.6E-76 T 29-03-2018 CVS48_RS26120 971e12a1b1a9226fc6496b89f4d84121 591 SUPERFAMILY SSF52540 343 588 2.77E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26120 971e12a1b1a9226fc6496b89f4d84121 591 SUPERFAMILY SSF90123 22 334 6.67E-71 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS26120 971e12a1b1a9226fc6496b89f4d84121 591 SMART SM00382 376 549 3.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS26120 971e12a1b1a9226fc6496b89f4d84121 591 Pfam PF00005 ABC transporter 368 517 1.9E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS26120 971e12a1b1a9226fc6496b89f4d84121 591 Gene3D G3DSA:1.20.1560.10 3 335 2.6E-62 T 29-03-2018 CVS48_RS26120 971e12a1b1a9226fc6496b89f4d84121 591 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 20 590 1.2E-262 T 29-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 CVS48_RS26120 971e12a1b1a9226fc6496b89f4d84121 591 Pfam PF00664 ABC transporter transmembrane region 34 304 1.2E-44 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS10235 6b2f2e278cd81921f8be80ead2c91ef9 478 Gene3D G3DSA:3.40.605.10 1 261 5.1E-91 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS10235 6b2f2e278cd81921f8be80ead2c91ef9 478 Gene3D G3DSA:3.40.309.10 262 458 1.5E-63 T 29-03-2018 CVS48_RS10235 6b2f2e278cd81921f8be80ead2c91ef9 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS10235 6b2f2e278cd81921f8be80ead2c91ef9 478 SUPERFAMILY SSF53720 2 472 8.12E-153 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS10235 6b2f2e278cd81921f8be80ead2c91ef9 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS10235 6b2f2e278cd81921f8be80ead2c91ef9 478 Pfam PF00171 Aldehyde dehydrogenase family 14 471 5.5E-156 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 533 4.7E-43 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 Pfam PF03129 Anticodon binding domain 545 634 4.2E-19 T 29-03-2018 IPR004154 Anticodon-binding CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 SUPERFAMILY SSF81271 2 66 1.37E-11 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 SUPERFAMILY SSF55681 247 530 1.09E-99 T 29-03-2018 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 511 524 1.4E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 538 550 1.4E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 1.4E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 468 496 1.4E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 1.4E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 Gene3D G3DSA:3.40.50.800 537 647 2.2E-26 T 29-03-2018 IPR004154 Anticodon-binding CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 175 223 4.6E-15 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 Pfam PF02824 TGS domain 2 66 3.2E-8 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 SUPERFAMILY SSF55186 69 245 2.88E-68 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 71 638 34.066 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 Gene3D G3DSA:3.30.930.10 233 535 9.7E-119 T 29-03-2018 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 SMART SM00863 174 223 9.3E-25 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 Gene3D G3DSA:3.30.980.10 75 232 2.5E-45 T 29-03-2018 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 SUPERFAMILY SSF52954 534 636 1.28E-29 T 29-03-2018 IPR004154 Anticodon-binding CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 77 635 1.2E-214 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CVS48_RS15120 de99bb45163ad4ee2e7c3a68254e651d 650 Gene3D G3DSA:3.10.20.30 1 69 1.9E-17 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS00500 c1f2b0bf5432d5510882fbc4596ce30a 411 Gene3D G3DSA:1.20.1600.10 21 410 1.0E-28 T 29-03-2018 CVS48_RS00500 c1f2b0bf5432d5510882fbc4596ce30a 411 Pfam PF02321 Outer membrane efflux protein 238 409 2.8E-9 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS00500 c1f2b0bf5432d5510882fbc4596ce30a 411 Pfam PF02321 Outer membrane efflux protein 30 213 5.2E-12 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS00500 c1f2b0bf5432d5510882fbc4596ce30a 411 SUPERFAMILY SSF56954 2 407 1.7E-41 T 29-03-2018 CVS48_RS02265 4dd20bd111104dcd3e971ea65bbb4f3a 201 Pfam PF03352 Methyladenine glycosylase 16 186 4.8E-69 T 29-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CVS48_RS02265 4dd20bd111104dcd3e971ea65bbb4f3a 201 SUPERFAMILY SSF48150 12 187 2.04E-68 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CVS48_RS02265 4dd20bd111104dcd3e971ea65bbb4f3a 201 Gene3D G3DSA:1.10.340.30 11 187 3.8E-73 T 29-03-2018 CVS48_RS19485 8c64edfbf758843e509cfce54ea61e1b 406 Pfam PF06969 HemN C-terminal domain 334 395 3.2E-13 T 29-03-2018 IPR010723 HemN, C-terminal CVS48_RS19485 8c64edfbf758843e509cfce54ea61e1b 406 Pfam PF04055 Radical SAM superfamily 36 198 5.0E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS19485 8c64edfbf758843e509cfce54ea61e1b 406 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 33 375 2.1E-104 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CVS48_RS19485 8c64edfbf758843e509cfce54ea61e1b 406 Gene3D G3DSA:1.10.10.10 329 405 3.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19485 8c64edfbf758843e509cfce54ea61e1b 406 SMART SM00729 31 247 8.4E-48 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CVS48_RS19485 8c64edfbf758843e509cfce54ea61e1b 406 Gene3D G3DSA:3.20.20.70 14 328 4.8E-42 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS19485 8c64edfbf758843e509cfce54ea61e1b 406 SUPERFAMILY SSF102114 17 406 1.44E-106 T 29-03-2018 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 4.2E-22 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 300 315 4.2E-22 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 4.2E-22 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 4.2E-22 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 394 405 4.2E-22 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 261 272 4.2E-22 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 Gene3D G3DSA:2.20.28.20 139 172 4.5E-15 T 29-03-2018 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 Gene3D G3DSA:3.40.50.620 260 382 1.6E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 Gene3D G3DSA:2.170.220.10 178 259 1.2E-10 T 29-03-2018 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 573 688 2.6E-39 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 SUPERFAMILY SSF57770 139 173 2.49E-12 T 29-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 SUPERFAMILY SSF52374 4 138 1.57E-88 T 29-03-2018 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 SUPERFAMILY SSF52374 173 397 1.57E-88 T 29-03-2018 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 Gene3D G3DSA:2.40.50.140 574 688 2.3E-28 T 29-03-2018 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 Pfam PF01588 Putative tRNA binding domain 588 669 1.6E-21 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 550 4.1E-147 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 SUPERFAMILY SSF50249 581 687 5.63E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 Gene3D G3DSA:1.10.730.10 383 552 1.5E-28 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 SUPERFAMILY SSF47323 396 596 1.81E-29 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 Gene3D G3DSA:3.40.50.620 1 78 8.9E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 561 37.161 T 29-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CVS48_RS10510 38f7cb07c938b70b211d8248f1f2e4a4 688 Pfam PF09334 tRNA synthetases class I (M) 6 406 1.6E-136 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 SUPERFAMILY SSF51735 5 247 1.19E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 247 8.9E-63 T 29-03-2018 CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 142 0.0022 T 29-03-2018 CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 Gene3D G3DSA:3.40.50.720 41 248 9.7E-62 T 29-03-2018 CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 Gene3D G3DSA:3.40.50.720 1 40 6.3E-10 T 29-03-2018 CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20845 737c22def88bf74f95c1e5452a5c552b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23895 98ef36c381489cfba9e121e248838901 160 Pfam PF01047 MarR family 27 85 1.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS23895 98ef36c381489cfba9e121e248838901 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 44 60 1.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS23895 98ef36c381489cfba9e121e248838901 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 1.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS23895 98ef36c381489cfba9e121e248838901 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 1.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS23895 98ef36c381489cfba9e121e248838901 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 76 1.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS23895 98ef36c381489cfba9e121e248838901 160 SMART SM00347 22 120 3.5E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS23895 98ef36c381489cfba9e121e248838901 160 SUPERFAMILY SSF46785 2 132 6.66E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23895 98ef36c381489cfba9e121e248838901 160 Gene3D G3DSA:1.10.10.10 1 142 4.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13370 09f1cb369160281535739fd14bf63b5d 440 SUPERFAMILY SSF55031 220 330 3.14E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS13370 09f1cb369160281535739fd14bf63b5d 440 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 103 112 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CVS48_RS13370 09f1cb369160281535739fd14bf63b5d 440 SUPERFAMILY SSF53187 350 434 2.43E-56 T 29-03-2018 CVS48_RS13370 09f1cb369160281535739fd14bf63b5d 440 SUPERFAMILY SSF53187 13 219 2.43E-56 T 29-03-2018 CVS48_RS13370 09f1cb369160281535739fd14bf63b5d 440 Pfam PF01546 Peptidase family M20/M25/M40 104 430 4.6E-34 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS13370 09f1cb369160281535739fd14bf63b5d 440 Pfam PF07687 Peptidase dimerisation domain 218 329 7.0E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS13370 09f1cb369160281535739fd14bf63b5d 440 Gene3D G3DSA:3.40.630.10 5 329 6.0E-55 T 29-03-2018 CVS48_RS13370 09f1cb369160281535739fd14bf63b5d 440 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 29 422 1.4E-73 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CVS48_RS27180 b9826e073338bb768230bfc430584a2e 401 Pfam PF04079 Segregation and condensation complex subunit ScpB 12 171 5.0E-45 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CVS48_RS27180 b9826e073338bb768230bfc430584a2e 401 Gene3D G3DSA:1.10.10.10 1 86 4.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27180 b9826e073338bb768230bfc430584a2e 401 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 17 174 5.5E-30 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CVS48_RS27180 b9826e073338bb768230bfc430584a2e 401 SUPERFAMILY SSF46785 2 84 5.26E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27180 b9826e073338bb768230bfc430584a2e 401 SUPERFAMILY SSF46785 87 162 5.36E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27180 b9826e073338bb768230bfc430584a2e 401 Gene3D G3DSA:1.10.10.10 87 179 5.7E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF13018 Extended Signal Peptide of Type V secretion system 12 33 1.9E-7 T 29-03-2018 IPR024973 ESPR domain CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 SUPERFAMILY SSF51126 1002 1211 2.95E-17 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 SUPERFAMILY SSF51126 808 963 2.95E-17 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1088 1119 2.1E-7 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 699 730 2.4E-10 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1228 1258 3.2E-9 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 995 1026 1.1E-8 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 511 542 1.9E-10 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1159 1189 5.1E-11 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 SUPERFAMILY SSF103515 1456 1790 1.22E-62 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 SUPERFAMILY SSF51126 1201 1373 2.7E-14 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 SMART SM00869 1512 1780 3.4E-42 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF03797 Autotransporter beta-domain 1515 1770 6.5E-56 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF12951 Passenger-associated-transport-repeat 512 541 3.3E-9 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF12951 Passenger-associated-transport-repeat 579 599 0.13 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF12951 Passenger-associated-transport-repeat 1089 1118 2.6E-7 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF12951 Passenger-associated-transport-repeat 997 1025 2.0E-7 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF12951 Passenger-associated-transport-repeat 1162 1188 1.5E-7 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF12951 Passenger-associated-transport-repeat 1228 1257 7.8E-7 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF12951 Passenger-associated-transport-repeat 607 636 0.0046 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Pfam PF12951 Passenger-associated-transport-repeat 700 729 2.3E-8 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Gene3D G3DSA:2.160.20.20 774 1214 3.1E-7 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Gene3D G3DSA:2.160.20.20 308 554 0.0081 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 Gene3D G3DSA:2.40.128.130 1448 1790 1.3E-57 T 29-03-2018 CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 SUPERFAMILY SSF51126 487 829 1.44E-21 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS11850 8bfe08630384349a47afe91b0207ecc6 1790 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1300 1790 8.1E-45 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 CVS48_RS27095 483c2d723e2bbb4e350920df300f37b5 293 Hamap MF_00188 Protease HtpX [htpX]. 1 290 24.478 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CVS48_RS27095 483c2d723e2bbb4e350920df300f37b5 293 Gene3D G3DSA:3.30.2010.10 73 164 5.4E-21 T 29-03-2018 CVS48_RS27095 483c2d723e2bbb4e350920df300f37b5 293 Pfam PF01435 Peptidase family M48 81 289 1.2E-38 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CVS48_RS07980 b8786dc0f95ec5d3190b3c79cbc13fa6 161 SUPERFAMILY SSF53271 2 159 4.33E-26 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CVS48_RS07980 b8786dc0f95ec5d3190b3c79cbc13fa6 161 Pfam PF00156 Phosphoribosyl transferase domain 65 159 3.3E-11 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CVS48_RS07980 b8786dc0f95ec5d3190b3c79cbc13fa6 161 Gene3D G3DSA:3.40.50.2020 2 161 1.4E-24 T 29-03-2018 CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 Gene3D G3DSA:1.10.10.10 1 83 4.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.9E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.9E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.9E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 Pfam PF03466 LysR substrate binding domain 90 289 1.1E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 Gene3D G3DSA:3.40.190.10 88 180 2.6E-17 T 29-03-2018 CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 SUPERFAMILY SSF46785 1 107 8.16E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.0E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 Gene3D G3DSA:3.40.190.10 181 262 7.7E-12 T 29-03-2018 CVS48_RS25555 450808f1f9c576bf7623076308b63515 309 SUPERFAMILY SSF53850 91 295 2.44E-31 T 29-03-2018 CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 SUPERFAMILY SSF55021 324 395 4.2E-11 T 29-03-2018 CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 316 7.1E-35 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 Gene3D G3DSA:3.30.70.260 318 398 5.1E-8 T 29-03-2018 CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 Gene3D G3DSA:3.40.50.720 127 285 1.4E-46 T 29-03-2018 CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 284 1.4E-54 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 SUPERFAMILY SSF51735 98 285 8.94E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 SUPERFAMILY SSF52283 3 124 4.46E-37 T 29-03-2018 CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CVS48_RS03785 8502f90fc6dcd6d5b0758fca0d117b36 398 Gene3D G3DSA:3.40.50.720 1 126 5.9E-40 T 29-03-2018 CVS48_RS23960 8112ca500854a985b16c804308aab639 277 SUPERFAMILY SSF100950 9 257 1.13E-59 T 29-03-2018 CVS48_RS23960 8112ca500854a985b16c804308aab639 277 Gene3D G3DSA:3.40.1080.10 5 250 7.2E-44 T 29-03-2018 CVS48_RS23960 8112ca500854a985b16c804308aab639 277 SMART SM00882 11 231 3.0E-33 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS23960 8112ca500854a985b16c804308aab639 277 Pfam PF01144 Coenzyme A transferase 14 227 4.7E-22 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 SUPERFAMILY SSF51905 26 352 1.15E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 Gene3D G3DSA:3.50.50.60 7 94 1.6E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 Pfam PF01266 FAD dependent oxidoreductase 27 386 1.9E-56 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 Gene3D G3DSA:3.30.9.10 104 212 5.5E-15 T 29-03-2018 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 Gene3D G3DSA:3.30.9.10 213 351 6.1E-43 T 29-03-2018 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 39 49 9.9E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 344 350 9.9E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 375 387 9.9E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 26 38 9.9E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 100 112 9.9E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 55 67 9.9E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 408 513 1.5E-16 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS20040 fce0aa6044b34326dcf0e37407e14bca 531 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 380 390 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS12265 b76f924afb9774eeb9f7fc19549e5a0b 328 PIRSF PIRSF017082 1 326 3.9E-69 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS12265 b76f924afb9774eeb9f7fc19549e5a0b 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 8.6E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS12265 b76f924afb9774eeb9f7fc19549e5a0b 328 Gene3D G3DSA:3.40.190.10 126 235 7.9E-10 T 29-03-2018 CVS48_RS12265 b76f924afb9774eeb9f7fc19549e5a0b 328 SUPERFAMILY SSF53850 112 285 7.41E-12 T 29-03-2018 CVS48_RS07145 708f1777ca9eae36e3224b7c3deb764b 347 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 4 344 1.6E-122 T 29-03-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 CVS48_RS07145 708f1777ca9eae36e3224b7c3deb764b 347 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 77 335 3.1E-72 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CVS48_RS07145 708f1777ca9eae36e3224b7c3deb764b 347 SUPERFAMILY SSF53756 4 343 7.85E-65 T 29-03-2018 CVS48_RS07145 708f1777ca9eae36e3224b7c3deb764b 347 Gene3D G3DSA:3.40.50.2000 190 347 1.6E-26 T 29-03-2018 CVS48_RS07145 708f1777ca9eae36e3224b7c3deb764b 347 Gene3D G3DSA:3.40.50.2000 3 160 3.0E-36 T 29-03-2018 CVS48_RS13435 5e67232c49896ce293842be00c3f7984 275 Pfam PF01614 Bacterial transcriptional regulator 150 269 6.2E-32 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS13435 5e67232c49896ce293842be00c3f7984 275 SUPERFAMILY SSF55781 95 273 1.37E-48 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13435 5e67232c49896ce293842be00c3f7984 275 Gene3D G3DSA:3.30.450.40 100 275 3.1E-51 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13435 5e67232c49896ce293842be00c3f7984 275 Pfam PF09339 IclR helix-turn-helix domain 32 83 2.7E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS13435 5e67232c49896ce293842be00c3f7984 275 SUPERFAMILY SSF46785 32 101 1.97E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13435 5e67232c49896ce293842be00c3f7984 275 Gene3D G3DSA:1.10.10.10 30 89 1.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13435 5e67232c49896ce293842be00c3f7984 275 SMART SM00346 30 118 6.8E-20 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS21275 3aa564e24088f1a60ab6a2f9ab6d2662 317 SUPERFAMILY SSF53474 51 314 8.11E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21275 3aa564e24088f1a60ab6a2f9ab6d2662 317 Gene3D G3DSA:3.40.50.1820 3 317 8.7E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21275 3aa564e24088f1a60ab6a2f9ab6d2662 317 Pfam PF00561 alpha/beta hydrolase fold 67 241 1.4E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS21725 d90ab0af528030341581f311310629e5 233 SUPERFAMILY SSF89562 26 185 1.05E-47 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS21725 d90ab0af528030341581f311310629e5 233 Pfam PF03737 Aldolase/RraA 30 175 3.8E-41 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS21725 d90ab0af528030341581f311310629e5 233 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 6 226 4.3E-102 T 29-03-2018 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 CVS48_RS21725 d90ab0af528030341581f311310629e5 233 Gene3D G3DSA:3.50.30.40 20 195 5.5E-51 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 Hamap MF_00318 Enolase [eno]. 2 412 44.228 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 Gene3D G3DSA:3.20.20.120 128 428 3.2E-100 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 SMART SM01192 139 426 3.3E-218 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 SMART SM01193 4 134 1.8E-89 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 426 2.2E-204 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 ProSitePatterns PS00164 Enolase signature. 335 348 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 Gene3D G3DSA:3.30.390.10 3 127 1.0E-50 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 PRINTS PR00148 Enolase signature 335 349 3.0E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 PRINTS PR00148 Enolase signature 37 51 3.0E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 PRINTS PR00148 Enolase signature 312 323 3.0E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 PRINTS PR00148 Enolase signature 161 174 3.0E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 PRINTS PR00148 Enolase signature 107 123 3.0E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 PRINTS PR00148 Enolase signature 364 381 3.0E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 SUPERFAMILY SSF54826 4 136 5.96E-54 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 Pfam PF03952 Enolase, N-terminal domain 4 133 3.2E-56 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 SUPERFAMILY SSF51604 139 427 4.67E-128 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 1.1E-129 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS27990 998074b1778f55cd8efa46ca9a05dbf5 428 PIRSF PIRSF001400 1 426 1.5E-186 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS17460 1c0809d376dfb5a2b4081cf20a8049df 428 Pfam PF07804 HipA-like C-terminal domain 167 384 9.2E-40 T 29-03-2018 IPR012893 HipA-like, C-terminal CVS48_RS17460 1c0809d376dfb5a2b4081cf20a8049df 428 Pfam PF13657 HipA N-terminal domain 16 121 1.6E-11 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CVS48_RS14720 2a6bedf2646501e5e32f121cac4f7ac5 357 SUPERFAMILY SSF53383 5 355 2.2E-82 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS14720 2a6bedf2646501e5e32f121cac4f7ac5 357 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 211 220 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CVS48_RS14720 2a6bedf2646501e5e32f121cac4f7ac5 357 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 355 56.0 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CVS48_RS14720 2a6bedf2646501e5e32f121cac4f7ac5 357 Gene3D G3DSA:3.40.640.10 39 275 1.7E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS14720 2a6bedf2646501e5e32f121cac4f7ac5 357 Pfam PF00155 Aminotransferase class I and II 25 351 2.9E-61 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS14720 2a6bedf2646501e5e32f121cac4f7ac5 357 Gene3D G3DSA:3.90.1150.10 276 356 8.1E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS14720 2a6bedf2646501e5e32f121cac4f7ac5 357 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 354 1.3E-94 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 Gene3D G3DSA:3.30.160.40 222 305 1.3E-24 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 232 248 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 Gene3D G3DSA:3.40.190.10 108 200 3.9E-37 T 29-03-2018 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 Gene3D G3DSA:3.40.190.10 2 107 3.8E-43 T 29-03-2018 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 213 6.7E-77 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 SUPERFAMILY SSF54782 223 308 1.11E-25 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 PRINTS PR00151 Porphobilinogen deaminase signature 144 161 2.3E-44 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 PRINTS PR00151 Porphobilinogen deaminase signature 46 66 2.3E-44 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 PRINTS PR00151 Porphobilinogen deaminase signature 125 142 2.3E-44 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 PRINTS PR00151 Porphobilinogen deaminase signature 231 248 2.3E-44 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 2.3E-44 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 PIRSF PIRSF001438 2 312 6.9E-117 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 227 296 3.2E-18 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 SUPERFAMILY SSF53850 6 220 1.41E-80 T 29-03-2018 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 298 9.3E-108 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26800 76105ec84b979b71bdf188cb3a9e8c6c 315 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 298 38.388 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS22285 0787b8738e2e7bd0b34095d4ef5a9c49 216 Pfam PF09335 SNARE associated Golgi protein 39 163 1.4E-16 T 29-03-2018 IPR032816 SNARE associated Golgi protein CVS48_RS25300 7e9cc30855cfcaa3693ace540c9933e6 194 SMART SM00530 12 67 5.0E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS25300 7e9cc30855cfcaa3693ace540c9933e6 194 SUPERFAMILY SSF51182 78 187 1.13E-26 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS25300 7e9cc30855cfcaa3693ace540c9933e6 194 Pfam PF07883 Cupin domain 128 185 4.2E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS25300 7e9cc30855cfcaa3693ace540c9933e6 194 SUPERFAMILY SSF47413 7 72 4.35E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS25300 7e9cc30855cfcaa3693ace540c9933e6 194 Gene3D G3DSA:1.10.260.40 3 78 4.2E-18 T 29-03-2018 CVS48_RS25300 7e9cc30855cfcaa3693ace540c9933e6 194 Gene3D G3DSA:2.60.120.10 79 194 1.6E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS25300 7e9cc30855cfcaa3693ace540c9933e6 194 Pfam PF13560 Helix-turn-helix domain 8 67 3.2E-14 T 29-03-2018 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 440 490 8.9E-15 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 50 1.8E-8 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 SUPERFAMILY SSF52156 795 923 3.27E-37 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1014 17.363 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Gene3D G3DSA:2.40.30.10 684 783 5.5E-18 T 29-03-2018 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 SUPERFAMILY SSF50447 918 1014 1.83E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Gene3D G3DSA:2.40.30.10 917 1015 2.1E-26 T 29-03-2018 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 434 1016 9.1E-252 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 SUPERFAMILY SSF50447 690 771 1.81E-25 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Gene3D G3DSA:3.30.56.50 5 46 2.4E-11 T 29-03-2018 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Gene3D G3DSA:3.30.56.50 443 484 3.9E-10 T 29-03-2018 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Pfam PF00009 Elongation factor Tu GTP binding domain 522 677 3.0E-34 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 521 675 1.7E-31 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 ProSitePatterns PS01176 Initiation factor 2 signature. 967 989 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Pfam PF11987 Translation-initiation factor 2 802 906 8.2E-36 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 SUPERFAMILY SSF52540 512 689 5.22E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Gene3D G3DSA:3.40.50.300 513 683 2.9E-40 T 29-03-2018 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 SUPERFAMILY SSF46955 4 51 9.34E-9 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Gene3D G3DSA:3.40.50.10050 814 895 6.6E-27 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CVS48_RS27160 5b3f82d10a7c6ac708d1cd6ef7a4a9ad 1016 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 60 97 3.2E-15 T 29-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial CVS48_RS02700 16563876784d3f502625d95869306e87 166 ProSitePatterns PS01068 OmpA-like domain. 96 140 - T 29-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 CVS48_RS02700 16563876784d3f502625d95869306e87 166 SUPERFAMILY SSF103088 55 164 3.79E-31 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS02700 16563876784d3f502625d95869306e87 166 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 61 164 1.2E-40 T 29-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 CVS48_RS02700 16563876784d3f502625d95869306e87 166 Gene3D G3DSA:3.30.1330.60 39 166 2.0E-31 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS02700 16563876784d3f502625d95869306e87 166 Pfam PF00691 OmpA family 63 158 4.9E-21 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS02700 16563876784d3f502625d95869306e87 166 PRINTS PR01021 OMPA domain signature 64 86 1.6E-13 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS02700 16563876784d3f502625d95869306e87 166 PRINTS PR01021 OMPA domain signature 94 109 1.6E-13 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS02700 16563876784d3f502625d95869306e87 166 PRINTS PR01021 OMPA domain signature 109 125 1.6E-13 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS04435 0b5d24c0bf21fb2f550d00fb8e7371c0 705 Pfam PF10136 Site-specific recombinase 34 695 1.2E-220 T 29-03-2018 IPR011385 Putative site-specific recombinase Gcr CVS48_RS04435 0b5d24c0bf21fb2f550d00fb8e7371c0 705 PIRSF PIRSF015380 1 705 2.5E-203 T 29-03-2018 IPR011385 Putative site-specific recombinase Gcr CVS48_RS04435 0b5d24c0bf21fb2f550d00fb8e7371c0 705 Gene3D G3DSA:1.20.1080.10 351 608 2.9E-39 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CVS48_RS16275 7a579a7d40c0aa16a9da6ee189f9dc20 196 SUPERFAMILY SSF46689 5 74 2.94E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS16275 7a579a7d40c0aa16a9da6ee189f9dc20 196 SUPERFAMILY SSF48498 84 186 1.58E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS16275 7a579a7d40c0aa16a9da6ee189f9dc20 196 Gene3D G3DSA:1.10.357.10 61 187 9.4E-19 T 29-03-2018 CVS48_RS16275 7a579a7d40c0aa16a9da6ee189f9dc20 196 Gene3D G3DSA:1.10.10.60 5 60 3.6E-19 T 29-03-2018 CVS48_RS16275 7a579a7d40c0aa16a9da6ee189f9dc20 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.8E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS16275 7a579a7d40c0aa16a9da6ee189f9dc20 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS16275 7a579a7d40c0aa16a9da6ee189f9dc20 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS18585 94b195d2c599629de40da49579be9927 219 SMART SM00419 161 209 7.4E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS18585 94b195d2c599629de40da49579be9927 219 Pfam PF13545 Crp-like helix-turn-helix domain 142 215 6.7E-19 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS18585 94b195d2c599629de40da49579be9927 219 Gene3D G3DSA:1.10.10.10 138 216 1.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18585 94b195d2c599629de40da49579be9927 219 SUPERFAMILY SSF51206 19 136 2.09E-20 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CVS48_RS18585 94b195d2c599629de40da49579be9927 219 Pfam PF00027 Cyclic nucleotide-binding domain 25 104 5.9E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS18585 94b195d2c599629de40da49579be9927 219 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 183 198 1.6E-8 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS18585 94b195d2c599629de40da49579be9927 219 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 167 183 1.6E-8 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS18585 94b195d2c599629de40da49579be9927 219 SMART SM00100 1 122 2.3E-4 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS18585 94b195d2c599629de40da49579be9927 219 Gene3D G3DSA:2.60.120.10 19 137 7.8E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS18585 94b195d2c599629de40da49579be9927 219 SUPERFAMILY SSF46785 140 217 3.52E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26420 c745a7aeca693f692bd579c71c350d1a 90 SUPERFAMILY SSF47729 1 90 8.54E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CVS48_RS26420 c745a7aeca693f692bd579c71c350d1a 90 SMART SM00411 1 90 8.0E-40 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS26420 c745a7aeca693f692bd579c71c350d1a 90 Gene3D G3DSA:4.10.520.10 1 90 1.1E-35 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CVS48_RS26420 c745a7aeca693f692bd579c71c350d1a 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 6.7E-34 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS26420 c745a7aeca693f692bd579c71c350d1a 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 5.9E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS26420 c745a7aeca693f692bd579c71c350d1a 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 5.9E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS26420 c745a7aeca693f692bd579c71c350d1a 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 5.9E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS26420 c745a7aeca693f692bd579c71c350d1a 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CVS48_RS13845 5446629adc565e18344c7a909984d519 200 SMART SM01103 6 89 4.1E-35 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CVS48_RS13845 5446629adc565e18344c7a909984d519 200 Gene3D G3DSA:3.30.110.60 5 97 9.7E-19 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CVS48_RS13845 5446629adc565e18344c7a909984d519 200 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 14 90 9.0E-35 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CVS48_RS13845 5446629adc565e18344c7a909984d519 200 SUPERFAMILY SSF75471 5 91 1.83E-23 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CVS48_RS13845 5446629adc565e18344c7a909984d519 200 Pfam PF01985 CRS1 / YhbY (CRM) domain 6 89 3.6E-16 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CVS48_RS24615 003811f2d620bd7b247c665971810de9 299 Pfam PF04381 Putative exonuclease, RdgC 1 296 4.0E-114 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 CVS48_RS24615 003811f2d620bd7b247c665971810de9 299 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 36.479 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 CVS48_RS20265 710d1a99108a643969f5dec598dd9e60 203 SMART SM00464 3 199 8.5E-5 T 29-03-2018 IPR003111 Lon, substrate-binding domain CVS48_RS20265 710d1a99108a643969f5dec598dd9e60 203 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 4 197 4.1E-14 T 29-03-2018 IPR003111 Lon, substrate-binding domain CVS48_RS20265 710d1a99108a643969f5dec598dd9e60 203 SUPERFAMILY SSF88697 4 198 1.24E-44 T 29-03-2018 IPR015947 PUA-like domain CVS48_RS20265 710d1a99108a643969f5dec598dd9e60 203 Gene3D G3DSA:2.30.130.40 1 114 3.1E-19 T 29-03-2018 CVS48_RS20265 710d1a99108a643969f5dec598dd9e60 203 Gene3D G3DSA:1.10.4060.10 118 201 7.9E-16 T 29-03-2018 CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 SMART SM00382 43 242 9.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 SMART SM00382 317 510 5.2E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 ProSitePatterns PS00211 ABC transporters family signature. 433 447 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 Gene3D G3DSA:3.40.50.300 11 279 1.9E-58 T 29-03-2018 CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 Gene3D G3DSA:3.40.50.300 280 567 2.4E-71 T 29-03-2018 CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 512 544 1.0E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 276 3.7E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 SUPERFAMILY SSF52540 14 263 1.07E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 Pfam PF00005 ABC transporter 309 460 2.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 Pfam PF00005 ABC transporter 35 192 4.0E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28105 abbea5676c25efe7ae0f90b4ae59ec7c 605 SUPERFAMILY SSF52540 284 532 7.87E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04700 37e0386d0e0f18327bf0d133001fcb54 653 Gene3D G3DSA:1.25.40.10 67 181 1.3E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04700 37e0386d0e0f18327bf0d133001fcb54 653 Gene3D G3DSA:1.25.40.10 342 407 3.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04700 37e0386d0e0f18327bf0d133001fcb54 653 Gene3D G3DSA:1.25.40.10 182 291 1.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04700 37e0386d0e0f18327bf0d133001fcb54 653 SUPERFAMILY SSF48452 263 393 9.36E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04700 37e0386d0e0f18327bf0d133001fcb54 653 SUPERFAMILY SSF48452 81 346 6.35E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04700 37e0386d0e0f18327bf0d133001fcb54 653 Gene3D G3DSA:1.25.40.10 292 341 7.6E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS12895 a8706a27f0e08d8683be3a39061f4bd7 523 Gene3D G3DSA:1.20.1250.20 194 385 6.0E-19 T 29-03-2018 CVS48_RS12895 a8706a27f0e08d8683be3a39061f4bd7 523 Pfam PF07690 Major Facilitator Superfamily 207 375 3.7E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS12895 a8706a27f0e08d8683be3a39061f4bd7 523 Pfam PF07690 Major Facilitator Superfamily 11 187 7.0E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS12895 a8706a27f0e08d8683be3a39061f4bd7 523 SUPERFAMILY SSF103473 9 368 1.11E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS12895 a8706a27f0e08d8683be3a39061f4bd7 523 Gene3D G3DSA:1.20.1250.20 2 189 4.0E-15 T 29-03-2018 CVS48_RS12195 de5d92deee43ea10a4672b4dd861de27 167 Pfam PF08281 Sigma-70, region 4 108 157 6.2E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12195 de5d92deee43ea10a4672b4dd861de27 167 SUPERFAMILY SSF88659 92 165 3.18E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12195 de5d92deee43ea10a4672b4dd861de27 167 Gene3D G3DSA:1.10.1740.10 8 77 5.5E-10 T 29-03-2018 CVS48_RS12195 de5d92deee43ea10a4672b4dd861de27 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 162 1.1E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12195 de5d92deee43ea10a4672b4dd861de27 167 SUPERFAMILY SSF88946 11 93 3.69E-11 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12195 de5d92deee43ea10a4672b4dd861de27 167 Gene3D G3DSA:1.10.10.10 78 165 1.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12195 de5d92deee43ea10a4672b4dd861de27 167 Pfam PF04542 Sigma-70 region 2 13 75 1.6E-7 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS28520 027f435113c3887c93826c6466d30467 185 PIRSF PIRSF016661 1 184 2.1E-45 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CVS48_RS28520 027f435113c3887c93826c6466d30467 185 Pfam PF02632 BioY family 30 177 2.5E-38 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 SMART SM00091 21 89 0.047 T 29-03-2018 IPR000014 PAS domain CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 SMART SM00091 143 211 5.0 T 29-03-2018 IPR000014 PAS domain CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 Gene3D G3DSA:3.40.50.10600 135 260 1.6E-33 T 29-03-2018 CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 Gene3D G3DSA:3.40.50.10600 13 134 2.5E-34 T 29-03-2018 CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 SUPERFAMILY SSF58104 263 460 5.89E-47 T 29-03-2018 CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 30 140 2.9E-18 T 29-03-2018 IPR000014 PAS domain CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 264 1.5E-19 T 29-03-2018 IPR000014 PAS domain CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 SMART SM00086 94 136 1.1E-6 T 29-03-2018 IPR001610 PAC motif CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 SMART SM00086 216 258 6.1E-4 T 29-03-2018 IPR001610 PAC motif CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 Pfam PF08447 PAS fold 44 129 9.8E-16 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 Pfam PF08447 PAS fold 166 251 4.2E-15 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 SUPERFAMILY SSF55785 155 255 3.14E-25 T 29-03-2018 IPR000014 PAS domain CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 Gene3D G3DSA:1.10.287.950 261 460 4.4E-35 T 29-03-2018 CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 SUPERFAMILY SSF55785 32 136 8.55E-27 T 29-03-2018 IPR000014 PAS domain CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 SMART SM00283 247 469 5.2E-42 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS14225 9711ff9b9de1fcc2ce171eeda2a06d93 493 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 285 437 1.1E-42 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS20535 c592528a6ae6edf4ecf8302b077af908 239 Pfam PF11828 Protein of unknown function (DUF3348) 1 237 5.6E-90 T 29-03-2018 IPR021783 Protein of unknown function DUF3348 CVS48_RS20775 b787011fb35d3e21f4e5b03ea8133658 79 Gene3D G3DSA:3.30.429.10 1 79 1.8E-29 T 29-03-2018 CVS48_RS20775 b787011fb35d3e21f4e5b03ea8133658 79 SUPERFAMILY SSF55331 2 72 1.13E-18 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CVS48_RS20775 b787011fb35d3e21f4e5b03ea8133658 79 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 70 1.0E-19 T 29-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CVS48_RS20775 b787011fb35d3e21f4e5b03ea8133658 79 Pfam PF01361 Tautomerase enzyme 2 66 4.0E-19 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 Gene3D G3DSA:3.40.50.1220 206 354 3.5E-24 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 Gene3D G3DSA:3.40.50.970 22 205 3.0E-33 T 29-03-2018 CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 SUPERFAMILY SSF52467 205 362 2.05E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 214 347 1.7E-15 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 432 451 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 29 194 5.8E-40 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 SUPERFAMILY SSF52518 373 547 1.27E-43 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 SUPERFAMILY SSF52518 29 197 7.7E-40 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 Gene3D G3DSA:3.40.50.970 356 548 1.3E-37 T 29-03-2018 CVS48_RS25865 15e99f71b6502d97a8217e308ddbf4a8 548 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 405 545 6.3E-30 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS26155 c0459b1f914108543a4845101e493a98 250 Gene3D G3DSA:3.90.550.10 1 224 2.4E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS26155 c0459b1f914108543a4845101e493a98 250 SUPERFAMILY SSF53448 1 146 4.18E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS26155 c0459b1f914108543a4845101e493a98 250 Pfam PF00535 Glycosyl transferase family 2 4 124 9.6E-19 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 Gene3D G3DSA:3.90.1170.10 2 137 5.5E-50 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 6.9E-51 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.5E-59 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 SUPERFAMILY SSF54686 1 134 1.57E-54 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 2.3E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 2.3E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 2.3E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 2.3E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06420 8da785773b784ba86398c7a5ffedaec4 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.564 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS22925 43905d474e29170471f294ae82013880 278 SUPERFAMILY SSF51556 9 273 7.94E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS22925 43905d474e29170471f294ae82013880 278 Gene3D G3DSA:3.20.20.140 5 278 2.4E-43 T 29-03-2018 CVS48_RS22925 43905d474e29170471f294ae82013880 278 Pfam PF04909 Amidohydrolase 10 272 2.9E-37 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS00440 751a7dab2464d55c6be9c886f5e7dedf 334 Gene3D G3DSA:1.10.10.10 1 82 2.2E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00440 751a7dab2464d55c6be9c886f5e7dedf 334 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 2 329 1.0E-91 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CVS48_RS00440 751a7dab2464d55c6be9c886f5e7dedf 334 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 323 26.067 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CVS48_RS00440 751a7dab2464d55c6be9c886f5e7dedf 334 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 6 70 1.5E-7 T 29-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 CVS48_RS00440 751a7dab2464d55c6be9c886f5e7dedf 334 Pfam PF01628 HrcA protein C terminal domain 100 316 1.6E-57 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CVS48_RS00440 751a7dab2464d55c6be9c886f5e7dedf 334 SUPERFAMILY SSF46785 1 80 6.59E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00440 751a7dab2464d55c6be9c886f5e7dedf 334 SUPERFAMILY SSF55781 68 332 7.85E-61 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS00440 751a7dab2464d55c6be9c886f5e7dedf 334 PIRSF PIRSF005485 1 334 3.8E-107 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CVS48_RS00440 751a7dab2464d55c6be9c886f5e7dedf 334 Gene3D G3DSA:3.30.450.40 177 334 6.5E-43 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS28125 43b82de2927289bcb79724c24334e97e 366 Gene3D G3DSA:3.60.60.10 110 366 2.5E-30 T 29-03-2018 CVS48_RS28125 43b82de2927289bcb79724c24334e97e 366 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 125 351 4.2E-17 T 29-03-2018 IPR005079 Peptidase C45 CVS48_RS15095 c0c908c1f7bef48ef8ae786b4b4d6992 414 SUPERFAMILY SSF55031 214 330 1.62E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS15095 c0c908c1f7bef48ef8ae786b4b4d6992 414 Pfam PF01546 Peptidase family M20/M25/M40 81 406 1.7E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS15095 c0c908c1f7bef48ef8ae786b4b4d6992 414 Pfam PF07687 Peptidase dimerisation domain 211 314 1.9E-7 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS15095 c0c908c1f7bef48ef8ae786b4b4d6992 414 Gene3D G3DSA:3.40.630.10 3 244 1.4E-46 T 29-03-2018 CVS48_RS15095 c0c908c1f7bef48ef8ae786b4b4d6992 414 Gene3D G3DSA:3.40.630.10 245 412 7.8E-22 T 29-03-2018 CVS48_RS15095 c0c908c1f7bef48ef8ae786b4b4d6992 414 PIRSF PIRSF001235 5 414 9.4E-136 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CVS48_RS15095 c0c908c1f7bef48ef8ae786b4b4d6992 414 SUPERFAMILY SSF53187 337 409 8.57E-96 T 29-03-2018 CVS48_RS15095 c0c908c1f7bef48ef8ae786b4b4d6992 414 SUPERFAMILY SSF53187 5 224 8.57E-96 T 29-03-2018 CVS48_RS15095 c0c908c1f7bef48ef8ae786b4b4d6992 414 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 11 407 3.8E-128 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CVS48_RS15605 42d363f6bb7dab9c9f518ef55f024674 210 PIRSF PIRSF006324 1 209 7.2E-46 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS15605 42d363f6bb7dab9c9f518ef55f024674 210 Pfam PF01810 LysE type translocator 17 207 1.3E-31 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS16485 00abe4a73ce033492b3ec5c1d6568038 1351 Pfam PF01381 Helix-turn-helix 15 62 1.0E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS16485 00abe4a73ce033492b3ec5c1d6568038 1351 SMART SM00530 14 69 0.0029 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS16485 00abe4a73ce033492b3ec5c1d6568038 1351 SUPERFAMILY SSF47413 12 63 3.66E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS16485 00abe4a73ce033492b3ec5c1d6568038 1351 Gene3D G3DSA:1.10.260.40 10 106 4.4E-9 T 29-03-2018 CVS48_RS20880 6feaa01483aeeb401585e1b4f505f8f2 301 Gene3D G3DSA:3.40.50.1820 22 295 8.0E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS20880 6feaa01483aeeb401585e1b4f505f8f2 301 Pfam PF00561 alpha/beta hydrolase fold 54 283 2.1E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS20880 6feaa01483aeeb401585e1b4f505f8f2 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 79 94 3.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS20880 6feaa01483aeeb401585e1b4f505f8f2 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 139 3.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS20880 6feaa01483aeeb401585e1b4f505f8f2 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 240 254 3.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS20880 6feaa01483aeeb401585e1b4f505f8f2 301 SUPERFAMILY SSF53474 31 295 1.37E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS08775 21a0bed7b77f04b71b0dc3683ce4660a 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 320 6.4E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS08775 21a0bed7b77f04b71b0dc3683ce4660a 325 PIRSF PIRSF017082 1 324 3.0E-71 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS08775 21a0bed7b77f04b71b0dc3683ce4660a 325 SUPERFAMILY SSF53850 109 284 5.61E-11 T 29-03-2018 CVS48_RS08775 21a0bed7b77f04b71b0dc3683ce4660a 325 Gene3D G3DSA:3.40.190.10 129 292 4.3E-12 T 29-03-2018 CVS48_RS14065 360a3b77b56ca8294a3bdd43466a9913 310 SUPERFAMILY SSF46689 251 301 2.28E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS14065 360a3b77b56ca8294a3bdd43466a9913 310 Pfam PF12833 Helix-turn-helix domain 221 295 1.2E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS14065 360a3b77b56ca8294a3bdd43466a9913 310 Gene3D G3DSA:1.10.10.60 190 254 1.2E-16 T 29-03-2018 CVS48_RS14065 360a3b77b56ca8294a3bdd43466a9913 310 Pfam PF06719 AraC-type transcriptional regulator N-terminus 35 185 4.2E-46 T 29-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal CVS48_RS14065 360a3b77b56ca8294a3bdd43466a9913 310 SMART SM00342 215 298 9.3E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS14065 360a3b77b56ca8294a3bdd43466a9913 310 Gene3D G3DSA:1.10.10.60 255 310 1.5E-11 T 29-03-2018 CVS48_RS14065 360a3b77b56ca8294a3bdd43466a9913 310 SUPERFAMILY SSF46689 199 248 1.95E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05670 a1e4b18896da9eccfabcf6dc152c6a23 469 Gene3D G3DSA:1.20.1250.20 279 469 1.4E-14 T 29-03-2018 CVS48_RS05670 a1e4b18896da9eccfabcf6dc152c6a23 469 SUPERFAMILY SSF103473 16 213 1.48E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS05670 a1e4b18896da9eccfabcf6dc152c6a23 469 SUPERFAMILY SSF103473 262 464 1.48E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS05670 a1e4b18896da9eccfabcf6dc152c6a23 469 Gene3D G3DSA:1.20.1250.20 14 210 1.5E-32 T 29-03-2018 CVS48_RS05670 a1e4b18896da9eccfabcf6dc152c6a23 469 Pfam PF07690 Major Facilitator Superfamily 25 420 1.9E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS25420 3401e18aac09e8d306273e90eda32a71 287 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 22 284 8.0E-54 T 29-03-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CVS48_RS25420 3401e18aac09e8d306273e90eda32a71 287 Gene3D G3DSA:3.40.1190.20 17 285 2.8E-55 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS25420 3401e18aac09e8d306273e90eda32a71 287 SUPERFAMILY SSF53613 23 282 1.43E-62 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS25420 3401e18aac09e8d306273e90eda32a71 287 Pfam PF08543 Phosphomethylpyrimidine kinase 121 279 7.7E-23 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 SUPERFAMILY SSF55008 284 354 1.44E-12 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Gene3D G3DSA:1.20.1110.10 391 689 1.5E-33 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 679 685 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Pfam PF00403 Heavy-metal-associated domain 217 268 8.9E-5 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Pfam PF00403 Heavy-metal-associated domain 288 345 7.0E-6 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Pfam PF00403 Heavy-metal-associated domain 117 162 3.6E-6 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Pfam PF00403 Heavy-metal-associated domain 46 93 1.8E-5 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 425 978 4.1E-180 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Gene3D G3DSA:3.30.70.100 28 113 7.8E-12 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Gene3D G3DSA:3.30.70.100 282 354 2.1E-12 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Gene3D G3DSA:3.30.70.100 213 281 5.6E-7 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 SUPERFAMILY SSF81665 577 668 8.37E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 SUPERFAMILY SSF81665 424 479 8.37E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Pfam PF00122 E1-E2 ATPase 476 657 1.6E-54 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 822 832 2.8E-23 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 875 894 2.8E-23 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 899 911 2.8E-23 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 677 691 2.8E-23 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 526 540 2.8E-23 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Gene3D G3DSA:3.40.1110.10 690 800 1.8E-27 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 448 959 1.3E-79 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 SUPERFAMILY SSF55008 42 107 1.17E-11 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 SUPERFAMILY SSF55008 214 278 2.62E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 SUPERFAMILY SSF56784 676 695 6.34E-54 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 SUPERFAMILY SSF56784 733 975 6.34E-54 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00941 Cadmium-transporting ATPase signature 542 558 8.4E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00941 Cadmium-transporting ATPase signature 218 227 8.4E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00941 Cadmium-transporting ATPase signature 460 480 8.4E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00941 Cadmium-transporting ATPase signature 406 418 8.4E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 PRINTS PR00941 Cadmium-transporting ATPase signature 561 575 8.4E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 SUPERFAMILY SSF55008 115 177 2.62E-9 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 SUPERFAMILY SSF81653 478 576 2.88E-23 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Gene3D G3DSA:3.40.50.1000 801 943 5.1E-36 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Gene3D G3DSA:3.30.70.100 114 182 1.9E-8 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 407 978 4.4E-121 T 29-03-2018 CVS48_RS00915 115d34ce2b4a3ef17b29c5ebb3027ca9 984 Pfam PF00702 haloacid dehalogenase-like hydrolase 674 889 6.7E-42 T 29-03-2018 CVS48_RS17625 9ffca009b7a101eaeac0ca17cd712064 617 SUPERFAMILY SSF51998 42 597 4.88E-157 T 29-03-2018 CVS48_RS17625 9ffca009b7a101eaeac0ca17cd712064 617 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 42 612 4.2E-183 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CVS48_RS17625 9ffca009b7a101eaeac0ca17cd712064 617 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 41 611 8.3E-149 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CVS48_RS17625 9ffca009b7a101eaeac0ca17cd712064 617 Gene3D G3DSA:3.20.70.20 50 597 2.3E-190 T 29-03-2018 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SMART SM00028 444 477 10.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SMART SM00028 307 340 0.051 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SMART SM00028 171 204 25.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SMART SM00028 409 442 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SMART SM00028 205 238 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SMART SM00028 137 170 0.014 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SMART SM00028 35 68 80.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 Gene3D G3DSA:1.25.40.10 428 499 1.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 Gene3D G3DSA:1.25.40.10 1 84 1.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 Gene3D G3DSA:1.25.40.10 188 216 3.8E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 Gene3D G3DSA:1.25.40.10 278 368 3.9E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SUPERFAMILY SSF48452 306 472 1.18E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 Gene3D G3DSA:1.25.40.10 217 277 5.5E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 Pfam PF13432 Tetratricopeptide repeat 279 340 8.4E-6 T 29-03-2018 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 Pfam PF13432 Tetratricopeptide repeat 149 199 3.1E-4 T 29-03-2018 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SUPERFAMILY SSF48452 15 104 2.45E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 SUPERFAMILY SSF48452 86 274 1.9E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 Gene3D G3DSA:1.25.40.10 369 427 9.4E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS29070 a90ded5a073fd7684e57d7e7c3325887 511 Gene3D G3DSA:1.25.40.10 85 187 4.1E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS25390 b10ce1eb5102dd26bb188e84d5365091 380 Pfam PF07730 Histidine kinase 181 246 2.1E-13 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CVS48_RS25390 b10ce1eb5102dd26bb188e84d5365091 380 Pfam PF00989 PAS fold 17 132 1.6E-13 T 29-03-2018 IPR013767 PAS fold GO:0006355 CVS48_RS25390 b10ce1eb5102dd26bb188e84d5365091 380 Gene3D G3DSA:3.30.450.20 11 191 3.2E-30 T 29-03-2018 CVS48_RS25390 b10ce1eb5102dd26bb188e84d5365091 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 354 1.6E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25390 b10ce1eb5102dd26bb188e84d5365091 380 SUPERFAMILY SSF55785 27 142 5.93E-23 T 29-03-2018 IPR000014 PAS domain CVS48_RS25390 b10ce1eb5102dd26bb188e84d5365091 380 Gene3D G3DSA:3.30.565.10 245 380 2.4E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25390 b10ce1eb5102dd26bb188e84d5365091 380 SUPERFAMILY SSF55874 262 377 2.36E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25390 b10ce1eb5102dd26bb188e84d5365091 380 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 142 5.9E-20 T 29-03-2018 IPR000014 PAS domain CVS48_RS25390 b10ce1eb5102dd26bb188e84d5365091 380 SMART SM00091 16 82 6.8E-10 T 29-03-2018 IPR000014 PAS domain CVS48_RS06650 f1de533a68d56b15de5ca525f1241053 359 Pfam PF06812 ImpA, N-terminal, type VI secretion system 10 129 5.8E-34 T 29-03-2018 IPR010657 ImpA, N-terminal CVS48_RS06650 f1de533a68d56b15de5ca525f1241053 359 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 1 348 9.4E-80 T 29-03-2018 IPR017740 Type VI secretion system-associated, ImpA CVS48_RS28575 5172f9d5b0714abdf08cf6a3a8eca2a6 340 Gene3D G3DSA:3.40.470.10 142 338 4.1E-63 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS28575 5172f9d5b0714abdf08cf6a3a8eca2a6 340 SMART SM00987 183 334 7.8E-44 T 29-03-2018 CVS48_RS28575 5172f9d5b0714abdf08cf6a3a8eca2a6 340 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 169 335 6.1E-64 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 CVS48_RS28575 5172f9d5b0714abdf08cf6a3a8eca2a6 340 SMART SM00986 183 334 7.8E-44 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS28575 5172f9d5b0714abdf08cf6a3a8eca2a6 340 Pfam PF03167 Uracil DNA glycosylase superfamily 183 334 2.8E-47 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS28575 5172f9d5b0714abdf08cf6a3a8eca2a6 340 SUPERFAMILY SSF52141 157 338 1.28E-61 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 PRINTS PR00969 Pili chaperone signature 34 43 1.5E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 PRINTS PR00969 Pili chaperone signature 111 128 1.5E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 PRINTS PR00969 Pili chaperone signature 83 104 1.5E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 PRINTS PR00969 Pili chaperone signature 135 150 1.5E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 PRINTS PR00969 Pili chaperone signature 175 190 1.5E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 Gene3D G3DSA:2.60.40.10 33 154 2.3E-31 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 180 245 3.0E-18 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 SUPERFAMILY SSF49354 29 153 6.25E-36 T 29-03-2018 IPR008962 PapD-like CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 34 153 9.4E-36 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 Gene3D G3DSA:2.60.40.10 156 252 3.3E-27 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS24985 79ff65426a23b2eb503b1c2b943c6ec3 253 SUPERFAMILY SSF49584 147 247 4.45E-16 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 Pfam PF08521 Two-component sensor kinase N-terminal 22 147 4.4E-10 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 399 1.9E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 1.9E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 385 1.9E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 Gene3D G3DSA:1.20.5.1040 7 56 1.2E-6 T 29-03-2018 CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 Gene3D G3DSA:1.20.5.1040 117 171 1.7E-9 T 29-03-2018 CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 288 1.8E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 SMART SM00388 224 289 4.8E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 SUPERFAMILY SSF47384 207 288 3.53E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 443 2.5E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 Gene3D G3DSA:1.10.287.130 214 283 1.6E-11 T 29-03-2018 CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 Gene3D G3DSA:3.30.565.10 284 444 2.7E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 SMART SM00387 334 444 3.2E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS27215 37786507a8b54f8d7f730a6308b1763c 444 SUPERFAMILY SSF55874 278 442 1.14E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS04215 5a0848f74cb814f365cebb57875bfed0 433 SMART SM00925 167 326 3.9E-92 T 29-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 CVS48_RS04215 5a0848f74cb814f365cebb57875bfed0 433 Pfam PF06725 3D domain 349 422 4.5E-24 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CVS48_RS04215 5a0848f74cb814f365cebb57875bfed0 433 Gene3D G3DSA:2.40.40.10 288 432 3.8E-36 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CVS48_RS04215 5a0848f74cb814f365cebb57875bfed0 433 Gene3D G3DSA:2.40.40.10 50 285 9.0E-32 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CVS48_RS04215 5a0848f74cb814f365cebb57875bfed0 433 PIRSF PIRSF019422 1 432 1.0E-126 T 29-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A CVS48_RS04215 5a0848f74cb814f365cebb57875bfed0 433 SUPERFAMILY SSF50685 57 426 1.4E-123 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CVS48_RS04215 5a0848f74cb814f365cebb57875bfed0 433 Pfam PF03562 MltA specific insert domain 75 326 3.0E-80 T 29-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 CVS48_RS10730 e92008b9684980ac83192d612b989886 209 Gene3D G3DSA:3.30.470.20 147 177 0.18 T 29-03-2018 CVS48_RS10730 e92008b9684980ac83192d612b989886 209 SUPERFAMILY SSF56059 33 157 6.67E-6 T 29-03-2018 CVS48_RS10730 e92008b9684980ac83192d612b989886 209 Gene3D G3DSA:3.30.470.20 30 146 2.4E-6 T 29-03-2018 CVS48_RS28220 4f5122ce23cc084c20d49efdb8e0afec 236 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 25 228 3.2E-41 T 29-03-2018 IPR006214 Bax inhibitor 1-related CVS48_RS13935 fb7557f12be670ae28d8e3bb956441d8 516 SUPERFAMILY SSF52518 341 515 3.22E-38 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS13935 fb7557f12be670ae28d8e3bb956441d8 516 SUPERFAMILY SSF52518 1 178 8.34E-40 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS13935 fb7557f12be670ae28d8e3bb956441d8 516 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 513 2.3E-24 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS13935 fb7557f12be670ae28d8e3bb956441d8 516 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 169 8.3E-38 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS13935 fb7557f12be670ae28d8e3bb956441d8 516 Gene3D G3DSA:3.40.50.970 311 516 8.8E-33 T 29-03-2018 CVS48_RS13935 fb7557f12be670ae28d8e3bb956441d8 516 Gene3D G3DSA:3.40.50.970 1 186 4.0E-40 T 29-03-2018 CVS48_RS08565 0275fdf00cc16c7fd1b9f8ed6b0b5b6d 172 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 6 158 7.2E-56 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CVS48_RS08565 0275fdf00cc16c7fd1b9f8ed6b0b5b6d 172 PIRSF PIRSF028301 1 171 5.4E-58 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CVS48_RS08565 0275fdf00cc16c7fd1b9f8ed6b0b5b6d 172 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 3 158 4.6E-53 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CVS48_RS10540 8c7808702f59ef0f583b6f58803badec 286 Gene3D G3DSA:3.40.630.30 216 283 1.2E-11 T 29-03-2018 CVS48_RS10540 8c7808702f59ef0f583b6f58803badec 286 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 120 5.0E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS10540 8c7808702f59ef0f583b6f58803badec 286 Gene3D G3DSA:3.10.180.10 1 131 2.3E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS10540 8c7808702f59ef0f583b6f58803badec 286 SUPERFAMILY SSF54593 5 125 5.64E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS10540 8c7808702f59ef0f583b6f58803badec 286 Pfam PF13673 Acetyltransferase (GNAT) domain 174 269 4.1E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS10540 8c7808702f59ef0f583b6f58803badec 286 SUPERFAMILY SSF55729 116 270 8.72E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS10540 8c7808702f59ef0f583b6f58803badec 286 Gene3D G3DSA:3.40.630.30 132 215 5.6E-12 T 29-03-2018 CVS48_RS03020 a3bb7a50cb784586e1e9b087a854de2b 236 SMART SM00382 29 230 7.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03020 a3bb7a50cb784586e1e9b087a854de2b 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS03020 a3bb7a50cb784586e1e9b087a854de2b 236 Gene3D G3DSA:3.40.50.300 1 234 6.0E-52 T 29-03-2018 CVS48_RS03020 a3bb7a50cb784586e1e9b087a854de2b 236 SUPERFAMILY SSF52540 4 234 9.16E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03020 a3bb7a50cb784586e1e9b087a854de2b 236 Pfam PF00005 ABC transporter 21 164 1.2E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19420 8a5f75442ba4f20a9b80b4fcd2ae6e6f 452 Gene3D G3DSA:3.40.50.720 10 103 0.0011 T 29-03-2018 CVS48_RS19420 8a5f75442ba4f20a9b80b4fcd2ae6e6f 452 Gene3D G3DSA:3.40.50.2300 104 230 9.4E-4 T 29-03-2018 CVS48_RS19420 8a5f75442ba4f20a9b80b4fcd2ae6e6f 452 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 8 353 8.9E-121 T 29-03-2018 IPR010839 Acyclic terpene utilisation CVS48_RS25345 196fb88a7abf776fe8fe70b16028555a 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 308 1.3E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS25345 196fb88a7abf776fe8fe70b16028555a 312 Gene3D G3DSA:1.10.3720.10 2 299 1.2E-42 T 29-03-2018 CVS48_RS25345 196fb88a7abf776fe8fe70b16028555a 312 SUPERFAMILY SSF161098 91 295 3.27E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10710 3db84dcbba2ac17bb9a2bbfc5e519823 380 Pfam PF13439 Glycosyltransferase Family 4 13 175 7.6E-17 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS10710 3db84dcbba2ac17bb9a2bbfc5e519823 380 Pfam PF00534 Glycosyl transferases group 1 184 338 8.8E-27 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS10710 3db84dcbba2ac17bb9a2bbfc5e519823 380 SUPERFAMILY SSF53756 2 374 5.38E-70 T 29-03-2018 CVS48_RS10710 3db84dcbba2ac17bb9a2bbfc5e519823 380 Gene3D G3DSA:3.40.50.2000 2 183 3.4E-22 T 29-03-2018 CVS48_RS10710 3db84dcbba2ac17bb9a2bbfc5e519823 380 Gene3D G3DSA:3.40.50.2000 184 359 1.9E-40 T 29-03-2018 CVS48_RS10365 b15c4cf83318f926185f63dedf0ef963 468 Gene3D G3DSA:1.25.40.10 209 428 1.0E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS10365 b15c4cf83318f926185f63dedf0ef963 468 SUPERFAMILY SSF48452 336 410 1.11E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS07880 f5dbdd2749d4464d8abbefc2f6bb8461 370 Gene3D G3DSA:3.40.50.450 120 271 4.2E-39 T 29-03-2018 CVS48_RS07880 f5dbdd2749d4464d8abbefc2f6bb8461 370 Gene3D G3DSA:1.10.10.10 294 370 5.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07880 f5dbdd2749d4464d8abbefc2f6bb8461 370 SUPERFAMILY SSF102405 88 297 1.12E-42 T 29-03-2018 CVS48_RS07880 f5dbdd2749d4464d8abbefc2f6bb8461 370 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 77 297 9.6E-74 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CVS48_RS07880 f5dbdd2749d4464d8abbefc2f6bb8461 370 Pfam PF02481 DNA recombination-mediator protein A 86 288 4.9E-75 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 Pfam PF00406 Adenylate kinase 5 185 6.9E-57 T 29-03-2018 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 PRINTS PR00094 Adenylate kinase signature 4 17 3.8E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 PRINTS PR00094 Adenylate kinase signature 156 171 3.8E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 PRINTS PR00094 Adenylate kinase signature 81 97 3.8E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 PRINTS PR00094 Adenylate kinase signature 173 187 3.8E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 PRINTS PR00094 Adenylate kinase signature 32 46 3.8E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 Pfam PF05191 Adenylate kinase, active site lid 123 158 2.5E-17 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 Gene3D G3DSA:3.40.50.300 1 218 2.8E-64 T 29-03-2018 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 SUPERFAMILY SSF52540 1 184 8.48E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 TIGRFAM TIGR01351 adk: adenylate kinase 2 199 6.9E-73 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CVS48_RS22480 90730e3750bec2f31f694024b32c6738 218 Hamap MF_00235 Adenylate kinase [adk]. 1 217 53.326 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CVS48_RS24485 085afde659a96707d933400d58f917eb 63 Gene3D G3DSA:1.10.10.10 1 63 1.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24485 085afde659a96707d933400d58f917eb 63 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 6 51 3.8E-15 T 29-03-2018 IPR010260 DNA-binding transcriptional activator AlpA CVS48_RS13735 3a2619a8563bbc72253d6f70bcab0840 202 SUPERFAMILY SSF111304 8 201 8.37E-68 T 29-03-2018 IPR023627 Recombination protein RecR CVS48_RS13735 3a2619a8563bbc72253d6f70bcab0840 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 87.097 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CVS48_RS13735 3a2619a8563bbc72253d6f70bcab0840 202 Gene3D G3DSA:3.40.1360.10 81 174 2.4E-31 T 29-03-2018 CVS48_RS13735 3a2619a8563bbc72253d6f70bcab0840 202 Pfam PF02132 RecR protein 44 82 7.9E-12 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CVS48_RS13735 3a2619a8563bbc72253d6f70bcab0840 202 SMART SM00493 84 169 3.1E-8 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS13735 3a2619a8563bbc72253d6f70bcab0840 202 Pfam PF13662 Toprim domain 85 175 6.1E-21 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS13735 3a2619a8563bbc72253d6f70bcab0840 202 TIGRFAM TIGR00615 recR: recombination protein RecR 8 200 1.4E-64 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CVS48_RS25875 fa952e699c99a361061d35a714db8b60 575 Gene3D G3DSA:3.40.50.980 20 231 5.3E-42 T 29-03-2018 CVS48_RS25875 fa952e699c99a361061d35a714db8b60 575 SUPERFAMILY SSF56801 14 160 5.63E-152 T 29-03-2018 CVS48_RS25875 fa952e699c99a361061d35a714db8b60 575 SUPERFAMILY SSF56801 196 571 5.63E-152 T 29-03-2018 CVS48_RS25875 fa952e699c99a361061d35a714db8b60 575 Pfam PF13193 AMP-binding enzyme C-terminal domain 484 561 4.9E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS25875 fa952e699c99a361061d35a714db8b60 575 Gene3D G3DSA:3.40.50.980 232 382 4.2E-43 T 29-03-2018 CVS48_RS25875 fa952e699c99a361061d35a714db8b60 575 Pfam PF00501 AMP-binding enzyme 29 474 3.0E-104 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS25875 fa952e699c99a361061d35a714db8b60 575 Gene3D G3DSA:3.30.300.30 469 575 1.6E-27 T 29-03-2018 CVS48_RS25875 fa952e699c99a361061d35a714db8b60 575 Gene3D G3DSA:2.30.38.10 383 468 6.0E-29 T 29-03-2018 CVS48_RS25875 fa952e699c99a361061d35a714db8b60 575 ProSitePatterns PS00455 Putative AMP-binding domain signature. 226 237 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS18840 b540b7c49be7b59f9ee45c0063882d99 317 PIRSF PIRSF028757 4 316 7.5E-79 T 29-03-2018 IPR003507 Peptidase family S66 CVS48_RS18840 b540b7c49be7b59f9ee45c0063882d99 317 SUPERFAMILY SSF52317 6 162 8.24E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS18840 b540b7c49be7b59f9ee45c0063882d99 317 Pfam PF02016 LD-carboxypeptidase 15 302 4.1E-77 T 29-03-2018 IPR003507 Peptidase family S66 CVS48_RS18840 b540b7c49be7b59f9ee45c0063882d99 317 SUPERFAMILY SSF141986 177 307 2.22E-36 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CVS48_RS18840 b540b7c49be7b59f9ee45c0063882d99 317 Gene3D G3DSA:3.40.50.10740 3 164 4.8E-49 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CVS48_RS18840 b540b7c49be7b59f9ee45c0063882d99 317 Gene3D G3DSA:3.50.30.60 165 316 1.3E-39 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CVS48_RS25715 df70bef45da5a218a42aee96e4a8cd1c 307 Gene3D G3DSA:3.90.550.10 2 227 1.4E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS25715 df70bef45da5a218a42aee96e4a8cd1c 307 Pfam PF00535 Glycosyl transferase family 2 7 115 1.2E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS25715 df70bef45da5a218a42aee96e4a8cd1c 307 SUPERFAMILY SSF53448 4 217 8.53E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 Gene3D G3DSA:3.40.190.10 90 177 5.2E-24 T 29-03-2018 CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 SUPERFAMILY SSF46785 4 88 6.04E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 Gene3D G3DSA:3.40.190.10 178 269 4.8E-23 T 29-03-2018 CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 Gene3D G3DSA:1.10.10.10 1 85 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 SUPERFAMILY SSF53850 90 293 1.55E-33 T 29-03-2018 CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 3.2E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01745 ddb5a8d54fe5fb7736c0f9ed48b3b2c8 303 Pfam PF03466 LysR substrate binding domain 89 289 3.2E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS10250 0cc03874090f7dfdfebdccc351a5a253 434 Gene3D G3DSA:3.40.50.2300 204 376 1.2E-10 T 29-03-2018 CVS48_RS10250 0cc03874090f7dfdfebdccc351a5a253 434 SUPERFAMILY SSF53822 31 414 1.51E-65 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS10250 0cc03874090f7dfdfebdccc351a5a253 434 Pfam PF13458 Periplasmic binding protein 31 375 4.9E-49 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS10250 0cc03874090f7dfdfebdccc351a5a253 434 Gene3D G3DSA:3.40.50.2300 27 203 5.8E-26 T 29-03-2018 CVS48_RS08215 f291822e72cb6b06fcab021e509c745a 210 SUPERFAMILY SSF161111 18 199 9.15E-31 T 29-03-2018 CVS48_RS08215 f291822e72cb6b06fcab021e509c745a 210 Gene3D G3DSA:1.20.1510.10 20 201 1.3E-17 T 29-03-2018 CVS48_RS08215 f291822e72cb6b06fcab021e509c745a 210 Pfam PF01545 Cation efflux family 24 199 1.3E-13 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CVS48_RS19390 d5ec4b404e1bd4aa87090da3f517967c 262 Pfam PF00106 short chain dehydrogenase 12 200 2.5E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19390 d5ec4b404e1bd4aa87090da3f517967c 262 Gene3D G3DSA:3.40.50.720 9 234 1.5E-42 T 29-03-2018 CVS48_RS19390 d5ec4b404e1bd4aa87090da3f517967c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 5.7E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19390 d5ec4b404e1bd4aa87090da3f517967c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 5.7E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19390 d5ec4b404e1bd4aa87090da3f517967c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 5.7E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19390 d5ec4b404e1bd4aa87090da3f517967c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.7E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19390 d5ec4b404e1bd4aa87090da3f517967c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.7E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19390 d5ec4b404e1bd4aa87090da3f517967c 262 SUPERFAMILY SSF51735 11 256 1.9E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19390 d5ec4b404e1bd4aa87090da3f517967c 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS16740 180f4a5261ac9e5e5443030d27401d53 356 Pfam PF16363 GDP-mannose 4,6 dehydratase 18 326 1.0E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS16740 180f4a5261ac9e5e5443030d27401d53 356 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 11 352 4.8E-139 T 29-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 CVS48_RS16740 180f4a5261ac9e5e5443030d27401d53 356 Gene3D G3DSA:3.40.50.720 5 199 3.6E-32 T 29-03-2018 CVS48_RS16740 180f4a5261ac9e5e5443030d27401d53 356 Gene3D G3DSA:3.90.25.10 200 356 5.2E-23 T 29-03-2018 CVS48_RS16740 180f4a5261ac9e5e5443030d27401d53 356 SUPERFAMILY SSF51735 11 336 1.77E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS20345 4c70de2413de495b898af9dfa42f9f0c 303 Gene3D G3DSA:1.10.3720.10 23 290 1.3E-39 T 29-03-2018 CVS48_RS20345 4c70de2413de495b898af9dfa42f9f0c 303 SUPERFAMILY SSF161098 96 283 4.32E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20345 4c70de2413de495b898af9dfa42f9f0c 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 300 1.6E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20345 4c70de2413de495b898af9dfa42f9f0c 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 72 3.6E-13 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS15550 1fda98592a8301daf133a84755650778 343 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 43 131 5.0E-6 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CVS48_RS15550 1fda98592a8301daf133a84755650778 343 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 179 294 2.3E-13 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CVS48_RS15550 1fda98592a8301daf133a84755650778 343 Gene3D G3DSA:2.30.110.10 163 329 6.4E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS15550 1fda98592a8301daf133a84755650778 343 SUPERFAMILY SSF50475 238 310 1.43E-9 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS15550 1fda98592a8301daf133a84755650778 343 Gene3D G3DSA:2.30.110.10 35 150 8.4E-9 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS02470 02d994f2c7767594acaeb7f897f29a41 358 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 7 354 34.082 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CVS48_RS02470 02d994f2c7767594acaeb7f897f29a41 358 Gene3D G3DSA:3.40.50.2000 175 348 7.4E-28 T 29-03-2018 CVS48_RS02470 02d994f2c7767594acaeb7f897f29a41 358 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 7 144 1.8E-34 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CVS48_RS02470 02d994f2c7767594acaeb7f897f29a41 358 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 349 1.8E-97 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CVS48_RS02470 02d994f2c7767594acaeb7f897f29a41 358 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 184 336 1.3E-34 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CVS48_RS02470 02d994f2c7767594acaeb7f897f29a41 358 SUPERFAMILY SSF53756 6 354 5.71E-117 T 29-03-2018 CVS48_RS02470 02d994f2c7767594acaeb7f897f29a41 358 Gene3D G3DSA:3.40.50.2000 1 174 1.0E-37 T 29-03-2018 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 Gene3D G3DSA:3.30.499.10 293 431 2.8E-52 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 Gene3D G3DSA:3.30.499.10 4 158 4.1E-29 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 15 427 8.9E-127 T 29-03-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 Gene3D G3DSA:3.40.1060.10 159 292 9.1E-34 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 PRINTS PR00415 Aconitase family signature 123 136 1.1E-21 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 PRINTS PR00415 Aconitase family signature 363 376 1.1E-21 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 PRINTS PR00415 Aconitase family signature 137 152 1.1E-21 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 PRINTS PR00415 Aconitase family signature 112 120 1.1E-21 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 PRINTS PR00415 Aconitase family signature 213 226 1.1E-21 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 PRINTS PR00415 Aconitase family signature 281 295 1.1E-21 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 PRINTS PR00415 Aconitase family signature 199 212 1.1E-21 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 SUPERFAMILY SSF53732 12 430 1.05E-125 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 Pfam PF00330 Aconitase family (aconitate hydratase) 297 421 1.3E-35 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16530 2faecfc30520cab266993251518729b2 431 Pfam PF00330 Aconitase family (aconitate hydratase) 36 297 1.6E-52 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.437 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 SUPERFAMILY SSF82679 3 113 3.79E-37 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 Pfam PF02357 Transcription termination factor nusG 3 108 1.3E-26 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 8.0E-69 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 Gene3D G3DSA:3.30.70.940 2 115 2.7E-42 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 1.6E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 1.6E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 1.6E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 SMART SM00739 123 150 4.8E-6 T 29-03-2018 IPR005824 KOW CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 SUPERFAMILY SSF50104 121 176 8.53E-20 T 29-03-2018 IPR008991 Translation protein SH3-like domain CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 Pfam PF00467 KOW motif 126 158 2.6E-7 T 29-03-2018 IPR005824 KOW CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 Gene3D G3DSA:2.30.30.30 118 177 1.2E-21 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CVS48_RS06250 8f11191cb50812bc46fe678e8de94edb 177 SMART SM00738 2 111 1.5E-45 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CVS48_RS13615 8612a7b4ab3d51d280d33f16096e6cb7 338 Gene3D G3DSA:3.90.180.10 1 192 6.6E-59 T 29-03-2018 CVS48_RS13615 8612a7b4ab3d51d280d33f16096e6cb7 338 SUPERFAMILY SSF50129 8 148 1.03E-36 T 29-03-2018 IPR011032 GroES-like CVS48_RS13615 8612a7b4ab3d51d280d33f16096e6cb7 338 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CVS48_RS13615 8612a7b4ab3d51d280d33f16096e6cb7 338 Pfam PF13602 Zinc-binding dehydrogenase 185 330 2.1E-33 T 29-03-2018 CVS48_RS13615 8612a7b4ab3d51d280d33f16096e6cb7 338 SUPERFAMILY SSF51735 115 297 5.5E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13615 8612a7b4ab3d51d280d33f16096e6cb7 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 87 1.5E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS13615 8612a7b4ab3d51d280d33f16096e6cb7 338 Gene3D G3DSA:3.90.180.10 193 333 4.1E-16 T 29-03-2018 CVS48_RS13615 8612a7b4ab3d51d280d33f16096e6cb7 338 SMART SM00829 13 330 5.1E-36 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS28225 9a6347bc60238734a5f074d532f254b3 305 Gene3D G3DSA:3.20.20.100 28 304 1.7E-48 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS28225 9a6347bc60238734a5f074d532f254b3 305 SUPERFAMILY SSF51430 32 286 3.4E-50 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS28225 9a6347bc60238734a5f074d532f254b3 305 Pfam PF00248 Aldo/keto reductase family 47 284 2.3E-31 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 SMART SM00345 13 71 1.6E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 Gene3D G3DSA:3.40.1410.10 78 247 1.9E-38 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 Pfam PF07702 UTRA domain 102 239 5.7E-34 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 69 4.6E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 SMART SM00866 101 239 3.0E-33 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 Gene3D G3DSA:1.10.10.10 3 70 4.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.0E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.0E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 SUPERFAMILY SSF46785 6 71 2.46E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16500 9bf30ff287b740494e7bc5f73189bc77 265 SUPERFAMILY SSF64288 91 244 2.36E-38 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS02860 56142f4dd46b4c676c75e545e896c7c2 261 SUPERFAMILY SSF51735 6 254 1.15E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS02860 56142f4dd46b4c676c75e545e896c7c2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02860 56142f4dd46b4c676c75e545e896c7c2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02860 56142f4dd46b4c676c75e545e896c7c2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02860 56142f4dd46b4c676c75e545e896c7c2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02860 56142f4dd46b4c676c75e545e896c7c2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02860 56142f4dd46b4c676c75e545e896c7c2 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 1.4E-86 T 29-03-2018 CVS48_RS02860 56142f4dd46b4c676c75e545e896c7c2 261 PIRSF PIRSF000094 1 260 9.3E-113 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS02860 56142f4dd46b4c676c75e545e896c7c2 261 Gene3D G3DSA:3.40.50.720 3 260 1.6E-40 T 29-03-2018 CVS48_RS20680 5a0f551883d6523785b1558e0aea8a9e 221 Pfam PF01584 CheW-like domain 75 216 7.2E-20 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS20680 5a0f551883d6523785b1558e0aea8a9e 221 Gene3D G3DSA:2.30.30.40 162 207 3.7E-7 T 29-03-2018 CVS48_RS20680 5a0f551883d6523785b1558e0aea8a9e 221 Gene3D G3DSA:2.40.50.180 91 161 5.4E-12 T 29-03-2018 CVS48_RS20680 5a0f551883d6523785b1558e0aea8a9e 221 SMART SM00260 70 213 5.5E-11 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS20680 5a0f551883d6523785b1558e0aea8a9e 221 SUPERFAMILY SSF50341 72 217 1.28E-24 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS28505 3c174207064d5677b18051ae7674a8fc 612 Pfam PF00005 ABC transporter 363 520 1.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28505 3c174207064d5677b18051ae7674a8fc 612 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 297 2.4E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS28505 3c174207064d5677b18051ae7674a8fc 612 Gene3D G3DSA:3.40.50.300 340 592 1.4E-57 T 29-03-2018 CVS48_RS28505 3c174207064d5677b18051ae7674a8fc 612 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 570 591 4.2E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS28505 3c174207064d5677b18051ae7674a8fc 612 SMART SM00382 371 569 5.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28505 3c174207064d5677b18051ae7674a8fc 612 SUPERFAMILY SSF52540 345 590 6.02E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28505 3c174207064d5677b18051ae7674a8fc 612 Gene3D G3DSA:1.10.3470.10 4 302 6.9E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS13965 50678dd0bdfd8355bf0356c1eb614e91 163 Gene3D G3DSA:1.20.1260.10 26 137 7.4E-18 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS13965 50678dd0bdfd8355bf0356c1eb614e91 163 Pfam PF03713 Domain of unknown function (DUF305) 84 145 6.4E-11 T 29-03-2018 IPR005183 Domain of unknown function DUF305 CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 247 1.2E-54 T 29-03-2018 CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 185 0.0064 T 29-03-2018 CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 Gene3D G3DSA:3.40.50.720 2 248 1.7E-67 T 29-03-2018 CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 8.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 8.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12290 c13076b439fdea9e56523b988a27290e 248 SUPERFAMILY SSF51735 3 247 1.49E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS22150 8d6910f564ce117b302dbfcd85c53229 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS22150 8d6910f564ce117b302dbfcd85c53229 255 SUPERFAMILY SSF52096 10 255 1.37E-51 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS22150 8d6910f564ce117b302dbfcd85c53229 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 254 4.2E-26 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS22150 8d6910f564ce117b302dbfcd85c53229 255 Gene3D G3DSA:3.90.226.10 9 214 8.3E-39 T 29-03-2018 CVS48_RS22150 8d6910f564ce117b302dbfcd85c53229 255 Gene3D G3DSA:1.10.12.10 215 255 3.7E-5 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS25570 fe09faab8509b6f7f8e5530b63832386 437 SUPERFAMILY SSF48179 339 434 5.95E-23 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS25570 fe09faab8509b6f7f8e5530b63832386 437 SUPERFAMILY SSF51735 32 214 9.33E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25570 fe09faab8509b6f7f8e5530b63832386 437 SUPERFAMILY SSF48179 215 357 5.02E-32 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS25570 fe09faab8509b6f7f8e5530b63832386 437 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 36 213 3.9E-60 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS25570 fe09faab8509b6f7f8e5530b63832386 437 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 216 309 1.5E-26 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS25570 fe09faab8509b6f7f8e5530b63832386 437 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 344 430 2.2E-8 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS25570 fe09faab8509b6f7f8e5530b63832386 437 Gene3D G3DSA:1.10.1040.10 339 434 1.5E-16 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS25570 fe09faab8509b6f7f8e5530b63832386 437 Gene3D G3DSA:1.10.1040.10 215 314 1.1E-26 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS25570 fe09faab8509b6f7f8e5530b63832386 437 Gene3D G3DSA:3.40.50.720 16 214 2.3E-55 T 29-03-2018 CVS48_RS19780 2140ee208de354dbd4ab187e0490f246 393 Pfam PF07690 Major Facilitator Superfamily 9 335 1.2E-35 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS19780 2140ee208de354dbd4ab187e0490f246 393 Gene3D G3DSA:1.20.1250.20 193 393 9.5E-15 T 29-03-2018 CVS48_RS19780 2140ee208de354dbd4ab187e0490f246 393 Gene3D G3DSA:1.20.1250.20 3 192 4.3E-24 T 29-03-2018 CVS48_RS19780 2140ee208de354dbd4ab187e0490f246 393 SUPERFAMILY SSF103473 4 390 4.58E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS18975 9ee3ab2de5fa4b48a306f45c4145a254 301 PRINTS PR00605 Class IC cytochrome C signature 271 293 7.5E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CVS48_RS18975 9ee3ab2de5fa4b48a306f45c4145a254 301 PRINTS PR00605 Class IC cytochrome C signature 129 140 7.5E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CVS48_RS18975 9ee3ab2de5fa4b48a306f45c4145a254 301 Pfam PF00034 Cytochrome c 119 194 6.1E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18975 9ee3ab2de5fa4b48a306f45c4145a254 301 Gene3D G3DSA:1.10.760.10 208 295 7.6E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18975 9ee3ab2de5fa4b48a306f45c4145a254 301 Gene3D G3DSA:1.10.760.10 91 197 5.6E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18975 9ee3ab2de5fa4b48a306f45c4145a254 301 SUPERFAMILY SSF46626 110 196 2.66E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18975 9ee3ab2de5fa4b48a306f45c4145a254 301 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 227 292 3.4E-7 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18975 9ee3ab2de5fa4b48a306f45c4145a254 301 SUPERFAMILY SSF46626 227 296 1.75E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS10045 9d3cb2fd3c92a084c98a3f10b76da8ad 661 SUPERFAMILY SSF48317 241 350 1.16E-23 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS10045 9d3cb2fd3c92a084c98a3f10b76da8ad 661 Pfam PF12951 Passenger-associated-transport-repeat 513 541 1.3E-7 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS10045 9d3cb2fd3c92a084c98a3f10b76da8ad 661 Gene3D G3DSA:1.20.144.10 137 376 1.6E-28 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS10045 9d3cb2fd3c92a084c98a3f10b76da8ad 661 SMART SM00014 232 350 1.9E-12 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS10045 9d3cb2fd3c92a084c98a3f10b76da8ad 661 Pfam PF01569 PAP2 superfamily 242 347 2.5E-12 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS10045 9d3cb2fd3c92a084c98a3f10b76da8ad 661 SUPERFAMILY SSF51126 474 633 2.64E-12 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS10045 9d3cb2fd3c92a084c98a3f10b76da8ad 661 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 513 542 1.5E-10 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS22795 54ae0ea17a623531716d8a297a64737c 409 Gene3D G3DSA:3.10.28.20 288 383 3.5E-17 T 29-03-2018 CVS48_RS22795 54ae0ea17a623531716d8a297a64737c 409 Pfam PF03069 Acetamidase/Formamidase family 7 384 1.1E-177 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 CVS48_RS22795 54ae0ea17a623531716d8a297a64737c 409 Gene3D G3DSA:2.60.120.580 150 281 2.9E-32 T 29-03-2018 CVS48_RS22795 54ae0ea17a623531716d8a297a64737c 409 Gene3D G3DSA:2.60.120.580 2 149 1.5E-34 T 29-03-2018 CVS48_RS22795 54ae0ea17a623531716d8a297a64737c 409 SUPERFAMILY SSF141130 213 383 2.62E-78 T 29-03-2018 CVS48_RS22795 54ae0ea17a623531716d8a297a64737c 409 SUPERFAMILY SSF141130 16 164 2.62E-78 T 29-03-2018 CVS48_RS07415 6462b7c3351fd8bfc4823bb51babb3db 111 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 2 103 9.6E-32 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 76 326 1.7E-101 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 10 327 56.808 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 Gene3D G3DSA:1.10.150.130 8 143 3.2E-21 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 12 327 55.483 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 Pfam PF00589 Phage integrase family 141 312 2.5E-49 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 Gene3D G3DSA:1.10.443.10 144 321 5.3E-47 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 48 4.0E-6 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 77 118 1.5E-6 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 SUPERFAMILY SSF56349 135 324 4.12E-56 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS13565 43c4c3cd2e22f98f34c7bd0c80dcf23e 327 SUPERFAMILY SSF47823 11 129 2.16E-24 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CVS48_RS08915 3762eb2e02ab9ba3281dab58ada32112 233 Gene3D G3DSA:1.20.120.530 83 230 1.2E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS08915 3762eb2e02ab9ba3281dab58ada32112 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.7E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08915 3762eb2e02ab9ba3281dab58ada32112 233 SMART SM00895 90 219 1.1E-13 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS08915 3762eb2e02ab9ba3281dab58ada32112 233 SMART SM00345 22 80 9.3E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08915 3762eb2e02ab9ba3281dab58ada32112 233 Pfam PF07729 FCD domain 91 214 2.6E-21 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS08915 3762eb2e02ab9ba3281dab58ada32112 233 Gene3D G3DSA:1.10.10.10 6 82 5.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08915 3762eb2e02ab9ba3281dab58ada32112 233 SUPERFAMILY SSF48008 87 224 1.2E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS08915 3762eb2e02ab9ba3281dab58ada32112 233 SUPERFAMILY SSF46785 10 84 4.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11960 4ee5728e069ad1078132650d32c9b9f7 335 Pfam PF04261 Dyp-type peroxidase family 9 305 1.4E-94 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CVS48_RS11960 4ee5728e069ad1078132650d32c9b9f7 335 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 10 305 2.0E-88 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CVS48_RS11960 4ee5728e069ad1078132650d32c9b9f7 335 SUPERFAMILY SSF54909 8 310 1.79E-107 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS14480 ad0d8cee58e14565bd36a6d0399b38a0 778 SUPERFAMILY SSF56719 47 521 1.15E-147 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CVS48_RS14480 ad0d8cee58e14565bd36a6d0399b38a0 778 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 27 721 5.5E-226 T 29-03-2018 CVS48_RS14480 ad0d8cee58e14565bd36a6d0399b38a0 778 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 20 775 33.045 T 29-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CVS48_RS14480 ad0d8cee58e14565bd36a6d0399b38a0 778 SMART SM00434 27 499 1.9E-215 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14480 ad0d8cee58e14565bd36a6d0399b38a0 778 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 48 505 1.2E-128 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14480 ad0d8cee58e14565bd36a6d0399b38a0 778 Gene3D G3DSA:3.90.199.10 50 303 4.3E-109 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14480 ad0d8cee58e14565bd36a6d0399b38a0 778 Gene3D G3DSA:1.10.268.10 382 521 5.7E-42 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CVS48_RS14480 ad0d8cee58e14565bd36a6d0399b38a0 778 SUPERFAMILY SSF101904 536 764 1.44E-44 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CVS48_RS14480 ad0d8cee58e14565bd36a6d0399b38a0 778 Gene3D G3DSA:2.120.10.90 529 730 5.8E-43 T 29-03-2018 CVS48_RS23000 48e7e22b8717ea41a439560d4d11b198 429 Pfam PF01546 Peptidase family M20/M25/M40 88 422 4.0E-35 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS23000 48e7e22b8717ea41a439560d4d11b198 429 SUPERFAMILY SSF53187 12 239 4.0E-95 T 29-03-2018 CVS48_RS23000 48e7e22b8717ea41a439560d4d11b198 429 SUPERFAMILY SSF53187 352 424 4.0E-95 T 29-03-2018 CVS48_RS23000 48e7e22b8717ea41a439560d4d11b198 429 Gene3D G3DSA:3.40.630.10 10 267 3.8E-45 T 29-03-2018 CVS48_RS23000 48e7e22b8717ea41a439560d4d11b198 429 Gene3D G3DSA:3.40.630.10 268 425 1.2E-22 T 29-03-2018 CVS48_RS23000 48e7e22b8717ea41a439560d4d11b198 429 PIRSF PIRSF001235 12 429 1.4E-139 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CVS48_RS23000 48e7e22b8717ea41a439560d4d11b198 429 SUPERFAMILY SSF55031 229 344 2.09E-31 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS23000 48e7e22b8717ea41a439560d4d11b198 429 Pfam PF07687 Peptidase dimerisation domain 229 327 4.6E-5 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS23000 48e7e22b8717ea41a439560d4d11b198 429 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 19 422 1.4E-132 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 Gene3D G3DSA:3.30.70.1430 42 135 1.7E-23 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 Gene3D G3DSA:3.30.70.1430 568 670 1.3E-13 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 SUPERFAMILY SSF82866 299 506 4.97E-35 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 Gene3D G3DSA:1.20.1640.10 822 1040 4.5E-41 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 Gene3D G3DSA:1.20.1640.10 293 519 8.0E-36 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 SUPERFAMILY SSF82693 575 668 3.77E-6 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 SUPERFAMILY SSF82693 42 128 2.35E-22 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1044 0.0 T 29-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 SUPERFAMILY SSF82866 815 1041 4.05E-58 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 Gene3D G3DSA:3.30.2090.10 190 277 8.7E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 Pfam PF00873 AcrB/AcrD/AcrF family 6 1038 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 Gene3D G3DSA:3.30.2090.10 725 819 2.5E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 SUPERFAMILY SSF82693 155 191 1.16E-19 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 SUPERFAMILY SSF82693 277 333 1.16E-19 T 29-03-2018 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 SUPERFAMILY SSF82714 193 274 6.41E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 2.6E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.6E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 2.6E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 2.6E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 2.6E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS08270 1a5c20ea81f27c043b987b1e7bb9c329 1052 SUPERFAMILY SSF82714 726 817 1.44E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS00290 65b5a6bcb6d48242416a9cb8b262533c 96 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 15 84 1.1E-26 T 29-03-2018 IPR019886 Sodium symporter small subunit, predicted CVS48_RS00290 65b5a6bcb6d48242416a9cb8b262533c 96 Pfam PF13937 Domain of unknown function (DUF4212) 14 83 1.1E-24 T 29-03-2018 IPR019886 Sodium symporter small subunit, predicted CVS48_RS11670 171ab47c9b67f4d77da546afdb86c792 378 Gene3D G3DSA:3.40.50.1970 8 182 1.2E-47 T 29-03-2018 CVS48_RS11670 171ab47c9b67f4d77da546afdb86c792 378 Gene3D G3DSA:1.20.1090.10 183 378 1.7E-48 T 29-03-2018 CVS48_RS11670 171ab47c9b67f4d77da546afdb86c792 378 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 369 4.1E-106 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CVS48_RS11670 171ab47c9b67f4d77da546afdb86c792 378 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CVS48_RS11670 171ab47c9b67f4d77da546afdb86c792 378 SUPERFAMILY SSF56796 4 376 6.41E-112 T 29-03-2018 CVS48_RS11900 e02660e39c1ef4fcb6fba54163cd5a0d 417 Pfam PF13657 HipA N-terminal domain 23 104 6.0E-12 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CVS48_RS11900 e02660e39c1ef4fcb6fba54163cd5a0d 417 Pfam PF07804 HipA-like C-terminal domain 144 376 7.6E-40 T 29-03-2018 IPR012893 HipA-like, C-terminal CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 29-03-2018 IPR018253 DnaJ domain, conserved site CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 Gene3D G3DSA:2.60.260.20 197 257 9.5E-20 T 29-03-2018 CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 Gene3D G3DSA:2.10.230.10 150 196 1.8E-13 T 29-03-2018 CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 SMART SM00271 4 62 3.5E-32 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 PRINTS PR00625 DnaJ domain signature 25 40 4.6E-33 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 PRINTS PR00625 DnaJ domain signature 42 62 4.6E-33 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 PRINTS PR00625 DnaJ domain signature 62 81 4.6E-33 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 PRINTS PR00625 DnaJ domain signature 7 25 4.6E-33 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 SUPERFAMILY SSF57938 137 213 4.05E-22 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 Gene3D G3DSA:1.10.287.110 1 113 4.2E-37 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 SUPERFAMILY SSF46565 1 111 1.19E-37 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 Pfam PF01556 DnaJ C terminal domain 124 336 4.4E-41 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 Gene3D G3DSA:2.60.260.20 258 368 1.9E-29 T 29-03-2018 CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 Pfam PF00226 DnaJ domain 5 67 3.6E-28 T 29-03-2018 IPR001623 DnaJ domain CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 352 1.7E-137 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 375 41.882 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 SUPERFAMILY SSF49493 262 347 1.27E-23 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 SUPERFAMILY SSF49493 189 264 3.14E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 SUPERFAMILY SSF49493 118 141 3.14E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CVS48_RS00410 73bc40f29c85b1efcfe657dc7eb4971a 377 Pfam PF00684 DnaJ central domain 150 210 6.5E-14 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CVS48_RS07600 48504d1cf9c23092d4ac9fe7958d2cab 262 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 256 3.1E-72 T 29-03-2018 CVS48_RS07600 48504d1cf9c23092d4ac9fe7958d2cab 262 SUPERFAMILY SSF56219 2 259 1.14E-74 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS07600 48504d1cf9c23092d4ac9fe7958d2cab 262 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 251 6.2E-18 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS07600 48504d1cf9c23092d4ac9fe7958d2cab 262 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CVS48_RS07600 48504d1cf9c23092d4ac9fe7958d2cab 262 Gene3D G3DSA:3.60.10.10 1 262 8.5E-53 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS07600 48504d1cf9c23092d4ac9fe7958d2cab 262 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 258 7.7E-77 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CVS48_RS15515 42829beb73495ccc0e6f28cec4611b16 299 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 239 280 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS15515 42829beb73495ccc0e6f28cec4611b16 299 SMART SM00342 202 284 4.2E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS15515 42829beb73495ccc0e6f28cec4611b16 299 Pfam PF02311 AraC-like ligand binding domain 19 95 4.8E-14 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS15515 42829beb73495ccc0e6f28cec4611b16 299 SUPERFAMILY SSF46689 238 285 5.82E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS15515 42829beb73495ccc0e6f28cec4611b16 299 Pfam PF12833 Helix-turn-helix domain 208 285 1.9E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS15515 42829beb73495ccc0e6f28cec4611b16 299 Gene3D G3DSA:1.10.10.60 244 295 2.6E-12 T 29-03-2018 CVS48_RS15515 42829beb73495ccc0e6f28cec4611b16 299 Gene3D G3DSA:1.10.10.60 183 243 5.1E-6 T 29-03-2018 CVS48_RS15515 42829beb73495ccc0e6f28cec4611b16 299 Gene3D G3DSA:2.60.120.10 15 147 3.7E-10 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS15515 42829beb73495ccc0e6f28cec4611b16 299 SUPERFAMILY SSF51215 26 147 6.8E-19 T 29-03-2018 CVS48_RS22110 5343acf5842490a77c383d18732ec0ef 513 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 452 1.1E-39 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CVS48_RS22110 5343acf5842490a77c383d18732ec0ef 513 SUPERFAMILY SSF53067 6 254 5.18E-52 T 29-03-2018 CVS48_RS22110 5343acf5842490a77c383d18732ec0ef 513 Gene3D G3DSA:3.30.420.40 2 248 8.9E-48 T 29-03-2018 CVS48_RS22110 5343acf5842490a77c383d18732ec0ef 513 SUPERFAMILY SSF53067 253 495 7.22E-53 T 29-03-2018 CVS48_RS22110 5343acf5842490a77c383d18732ec0ef 513 Gene3D G3DSA:3.30.420.40 249 512 7.0E-53 T 29-03-2018 CVS48_RS22110 5343acf5842490a77c383d18732ec0ef 513 PIRSF PIRSF000538 4 498 4.4E-100 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CVS48_RS22110 5343acf5842490a77c383d18732ec0ef 513 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 364 384 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CVS48_RS22110 5343acf5842490a77c383d18732ec0ef 513 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 251 9.7E-34 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 ProSitePatterns PS00450 Aconitase family signature 1. 705 722 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 8.5E-95 T 29-03-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 Gene3D G3DSA:3.40.1060.10 524 685 3.9E-27 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 PIRSF PIRSF036687 1 861 0.0 T 29-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 Gene3D G3DSA:3.30.499.10 686 863 1.0E-49 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 856 0.0 T 29-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 Gene3D G3DSA:3.20.19.10 162 363 9.8E-30 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 ProSitePatterns PS01244 Aconitase family signature 2. 763 776 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 Gene3D G3DSA:3.30.499.10 405 523 2.1E-10 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 Pfam PF11791 Aconitate B N-terminal domain 4 156 4.5E-65 T 29-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 SUPERFAMILY SSF74778 1 160 5.49E-67 T 29-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 SUPERFAMILY SSF53732 379 855 5.1E-146 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 Pfam PF00330 Aconitase family (aconitate hydratase) 475 816 7.9E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23475 17f1540788b98a868eb5317ce1e3d739 863 SUPERFAMILY SSF52016 162 372 3.34E-65 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS04580 0d63f3997429c7d5e8454d5f65a50498 247 Pfam PF06532 Protein of unknown function (DUF1109) 48 247 8.5E-43 T 29-03-2018 IPR009495 Anti-sigma-F factor NrsF CVS48_RS23075 6d3eef5d2c9376d59ba328769f8b770e 214 Pfam PF03006 Haemolysin-III related 10 206 5.0E-41 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CVS48_RS23075 6d3eef5d2c9376d59ba328769f8b770e 214 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 12 212 5.6E-61 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CVS48_RS14560 3782de79e11734817d445ca6b6d4df44 446 Gene3D G3DSA:3.40.190.10 37 171 3.9E-14 T 29-03-2018 CVS48_RS14560 3782de79e11734817d445ca6b6d4df44 446 SUPERFAMILY SSF53850 37 439 6.64E-48 T 29-03-2018 CVS48_RS14560 3782de79e11734817d445ca6b6d4df44 446 Pfam PF13416 Bacterial extracellular solute-binding protein 55 369 7.6E-29 T 29-03-2018 CVS48_RS14560 3782de79e11734817d445ca6b6d4df44 446 Gene3D G3DSA:3.40.190.10 172 364 2.0E-19 T 29-03-2018 CVS48_RS27970 b49a6601f56c6c49e7d0da7ef15be9b8 173 Gene3D G3DSA:2.160.10.10 1 173 1.1E-37 T 29-03-2018 CVS48_RS27970 b49a6601f56c6c49e7d0da7ef15be9b8 173 SUPERFAMILY SSF51161 1 169 1.52E-41 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS27970 b49a6601f56c6c49e7d0da7ef15be9b8 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 5.3E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS12295 416b1d1f38a06545c221444ca80aba6f 125 Gene3D G3DSA:2.60.120.10 3 107 3.9E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS12295 416b1d1f38a06545c221444ca80aba6f 125 Pfam PF07883 Cupin domain 36 94 2.8E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS12295 416b1d1f38a06545c221444ca80aba6f 125 SUPERFAMILY SSF51182 2 109 4.34E-26 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS26030 ad9fd3140200cbd2fd6b6099cf7b09cf 289 Gene3D G3DSA:3.40.190.10 172 255 3.5E-13 T 29-03-2018 CVS48_RS26030 ad9fd3140200cbd2fd6b6099cf7b09cf 289 Gene3D G3DSA:1.10.10.10 1 83 1.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26030 ad9fd3140200cbd2fd6b6099cf7b09cf 289 SUPERFAMILY SSF46785 1 110 3.74E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26030 ad9fd3140200cbd2fd6b6099cf7b09cf 289 Gene3D G3DSA:3.40.190.10 91 171 3.1E-13 T 29-03-2018 CVS48_RS26030 ad9fd3140200cbd2fd6b6099cf7b09cf 289 SUPERFAMILY SSF53850 89 286 2.71E-39 T 29-03-2018 CVS48_RS26030 ad9fd3140200cbd2fd6b6099cf7b09cf 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.0E-13 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS26030 ad9fd3140200cbd2fd6b6099cf7b09cf 289 Pfam PF03466 LysR substrate binding domain 88 284 3.3E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.6E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 2.5E-62 T 29-03-2018 CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 SUPERFAMILY SSF51735 1 249 1.96E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 Gene3D G3DSA:3.40.50.720 44 252 1.9E-62 T 29-03-2018 CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 Gene3D G3DSA:3.40.50.720 2 43 4.1E-8 T 29-03-2018 CVS48_RS01210 0bfcee398eee39fd2a09188f02355216 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 178 0.0097 T 29-03-2018 CVS48_RS10520 0957193aa8cb9e98aceea2dcee74aecf 362 Gene3D G3DSA:3.30.300.130 1 86 0.0015 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CVS48_RS10520 0957193aa8cb9e98aceea2dcee74aecf 362 SUPERFAMILY SSF52540 88 320 2.92E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10520 0957193aa8cb9e98aceea2dcee74aecf 362 Pfam PF01883 Iron-sulfur cluster assembly protein 6 73 2.1E-8 T 29-03-2018 IPR002744 MIP18 family-like CVS48_RS10520 0957193aa8cb9e98aceea2dcee74aecf 362 Hamap MF_02040 Iron-sulfur cluster carrier protein. 91 339 37.472 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CVS48_RS10520 0957193aa8cb9e98aceea2dcee74aecf 362 Gene3D G3DSA:3.40.50.300 87 317 5.9E-67 T 29-03-2018 CVS48_RS10520 0957193aa8cb9e98aceea2dcee74aecf 362 SUPERFAMILY SSF117916 4 84 2.55E-7 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CVS48_RS10520 0957193aa8cb9e98aceea2dcee74aecf 362 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 95 338 9.2E-102 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CVS48_RS10520 0957193aa8cb9e98aceea2dcee74aecf 362 ProSitePatterns PS01215 Mrp family signature. 202 218 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 CVS48_RS07900 cdddf32877d8b971876e091d600783f5 208 SUPERFAMILY SSF50475 31 176 9.91E-25 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS07900 cdddf32877d8b971876e091d600783f5 208 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 125 4.1E-17 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CVS48_RS07900 cdddf32877d8b971876e091d600783f5 208 Gene3D G3DSA:2.30.110.10 25 178 4.3E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS07900 cdddf32877d8b971876e091d600783f5 208 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 14 208 3.1E-82 T 29-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent CVS48_RS10625 bfbf003370ea611d3cbb265ae13b6ec7 521 PIRSF PIRSF002741 12 520 9.7E-65 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS10625 bfbf003370ea611d3cbb265ae13b6ec7 521 Gene3D G3DSA:3.10.105.10 286 494 1.8E-30 T 29-03-2018 CVS48_RS10625 bfbf003370ea611d3cbb265ae13b6ec7 521 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 443 2.4E-88 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS10625 bfbf003370ea611d3cbb265ae13b6ec7 521 Gene3D G3DSA:3.90.76.10 36 174 2.7E-31 T 29-03-2018 CVS48_RS10625 bfbf003370ea611d3cbb265ae13b6ec7 521 SUPERFAMILY SSF53850 23 516 1.05E-103 T 29-03-2018 CVS48_RS10625 bfbf003370ea611d3cbb265ae13b6ec7 521 Gene3D G3DSA:3.40.190.10 175 285 5.8E-19 T 29-03-2018 CVS48_RS11885 befb77d44ac2840a1920ab65aa74a3d4 259 SMART SM01007 28 207 1.1E-56 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS11885 befb77d44ac2840a1920ab65aa74a3d4 259 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 29 207 4.3E-43 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS11885 befb77d44ac2840a1920ab65aa74a3d4 259 Gene3D G3DSA:3.40.225.10 13 259 4.2E-74 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS11885 befb77d44ac2840a1920ab65aa74a3d4 259 SUPERFAMILY SSF53639 22 227 1.24E-59 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS14570 4b8a7e6d4751654c366b96efaa7b7347 529 Gene3D G3DSA:3.65.10.10 229 397 2.3E-4 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 Gene3D G3DSA:3.20.20.70 10 377 1.2E-110 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 41 57 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 Pfam PF00682 HMGL-like 34 312 2.8E-78 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 SUPERFAMILY SSF51569 23 331 1.59E-101 T 29-03-2018 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 6 554 1.5E-242 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 244 257 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 SUPERFAMILY SSF89000 389 439 1.65E-14 T 29-03-2018 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 7 555 53.855 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 SUPERFAMILY SSF110921 449 553 4.71E-33 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 SMART SM00917 423 554 1.7E-31 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CVS48_RS05400 487f4c9cdb0f4627e784595900596f8b 572 Pfam PF08502 LeuA allosteric (dimerisation) domain 423 552 7.0E-29 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CVS48_RS01765 19a8489c0090b2b0560628bd79bdb587 468 PIRSF PIRSF006060 3 468 4.0E-80 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CVS48_RS01765 19a8489c0090b2b0560628bd79bdb587 468 Pfam PF13520 Amino acid permease 27 422 2.2E-50 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CVS48_RS14635 75b9bdd97f6f32e49434186beb9b4e28 205 Pfam PF01782 RimM N-terminal domain 16 106 1.1E-22 T 29-03-2018 IPR002676 RimM protein GO:0006364 CVS48_RS14635 75b9bdd97f6f32e49434186beb9b4e28 205 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 15 204 1.1E-35 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CVS48_RS14635 75b9bdd97f6f32e49434186beb9b4e28 205 Gene3D G3DSA:2.40.30.60 13 111 1.2E-23 T 29-03-2018 IPR002676 RimM protein GO:0006364 CVS48_RS14635 75b9bdd97f6f32e49434186beb9b4e28 205 SUPERFAMILY SSF50346 117 205 8.63E-11 T 29-03-2018 IPR011033 PRC-barrel-like CVS48_RS14635 75b9bdd97f6f32e49434186beb9b4e28 205 SUPERFAMILY SSF50447 13 110 1.8E-16 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS14635 75b9bdd97f6f32e49434186beb9b4e28 205 Gene3D G3DSA:2.30.30.240 113 200 2.7E-20 T 29-03-2018 CVS48_RS14635 75b9bdd97f6f32e49434186beb9b4e28 205 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 14 205 22.839 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CVS48_RS13120 d845e7abd487dd0df8abae64c41e6102 243 Pfam PF04452 RNA methyltransferase 19 239 1.2E-65 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS13120 d845e7abd487dd0df8abae64c41e6102 243 Gene3D G3DSA:3.40.1280.10 1 243 7.5E-79 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CVS48_RS13120 d845e7abd487dd0df8abae64c41e6102 243 SUPERFAMILY SSF88697 3 58 1.76E-13 T 29-03-2018 IPR015947 PUA-like domain CVS48_RS13120 d845e7abd487dd0df8abae64c41e6102 243 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 18 241 4.1E-48 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS13120 d845e7abd487dd0df8abae64c41e6102 243 PIRSF PIRSF015601 2 243 3.7E-55 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS13120 d845e7abd487dd0df8abae64c41e6102 243 SUPERFAMILY SSF75217 74 242 1.7E-48 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CVS48_RS24660 425578b45dcf74616a0be1c1bbf1d732 397 Gene3D G3DSA:2.60.120.650 8 212 4.3E-27 T 29-03-2018 CVS48_RS24660 425578b45dcf74616a0be1c1bbf1d732 397 Pfam PF08007 Cupin superfamily protein 15 332 4.2E-84 T 29-03-2018 IPR003347 JmjC domain CVS48_RS24660 425578b45dcf74616a0be1c1bbf1d732 397 SMART SM00558 98 225 0.0017 T 29-03-2018 IPR003347 JmjC domain CVS48_RS24660 425578b45dcf74616a0be1c1bbf1d732 397 SUPERFAMILY SSF51197 6 306 5.22E-61 T 29-03-2018 CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 SUPERFAMILY SSF52540 340 584 9.08E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 Pfam PF00005 ABC transporter 367 514 6.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 SMART SM00382 374 566 7.8E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 Pfam PF00664 ABC transporter transmembrane region 34 300 2.0E-27 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 SUPERFAMILY SSF52172 768 897 1.24E-26 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 Gene3D G3DSA:3.40.50.300 340 590 6.9E-76 T 29-03-2018 CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 Pfam PF00072 Response regulator receiver domain 771 892 1.3E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 SUPERFAMILY SSF90123 18 337 6.67E-59 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 Gene3D G3DSA:1.20.1560.10 12 339 6.3E-50 T 29-03-2018 CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 Gene3D G3DSA:3.30.565.10 597 704 3.7E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 SMART SM00448 769 892 5.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 SUPERFAMILY SSF55874 592 682 9.23E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25705 fc5448d62121f82faed0e9083b71341c 906 Gene3D G3DSA:3.40.50.2300 763 898 6.7E-26 T 29-03-2018 CVS48_RS14850 73a55f351aa1f61627af30c60c9c27ee 122 Pfam PF02643 Uncharacterized ACR, COG1430 18 98 7.2E-12 T 29-03-2018 IPR003795 Protein of unknown function DUF192 CVS48_RS25685 f0b147cc23bb6247a0f20770c1487a69 372 SUPERFAMILY SSF53756 10 353 1.33E-66 T 29-03-2018 CVS48_RS25685 f0b147cc23bb6247a0f20770c1487a69 372 Gene3D G3DSA:3.40.50.2000 171 355 1.0E-40 T 29-03-2018 CVS48_RS25685 f0b147cc23bb6247a0f20770c1487a69 372 Gene3D G3DSA:3.40.50.2000 2 170 1.3E-27 T 29-03-2018 CVS48_RS25685 f0b147cc23bb6247a0f20770c1487a69 372 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 139 331 2.5E-19 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CVS48_RS24685 412cfe7ba1b8e387e40bd8ba84c006ff 208 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 2.3E-53 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CVS48_RS24685 412cfe7ba1b8e387e40bd8ba84c006ff 208 SUPERFAMILY SSF55821 1 202 5.19E-57 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CVS48_RS24685 412cfe7ba1b8e387e40bd8ba84c006ff 208 Gene3D G3DSA:3.90.870.10 1 206 2.9E-54 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CVS48_RS24685 412cfe7ba1b8e387e40bd8ba84c006ff 208 Pfam PF01300 Telomere recombination 23 198 1.7E-38 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CVS48_RS11495 e5376539b63a0dc3d9ea1005053c478e 541 Gene3D G3DSA:3.10.20.310 56 128 5.9E-15 T 29-03-2018 CVS48_RS11495 e5376539b63a0dc3d9ea1005053c478e 541 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 191 502 3.3E-29 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal CVS48_RS11495 e5376539b63a0dc3d9ea1005053c478e 541 Gene3D G3DSA:2.40.160.50 158 541 5.6E-48 T 29-03-2018 CVS48_RS11495 e5376539b63a0dc3d9ea1005053c478e 541 Pfam PF08479 POTRA domain, ShlB-type 53 128 2.0E-17 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type CVS48_RS00135 4c1c739aae2a9e709d6dc2199b4e70fe 325 Pfam PF00795 Carbon-nitrogen hydrolase 8 277 5.2E-55 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS00135 4c1c739aae2a9e709d6dc2199b4e70fe 325 Gene3D G3DSA:3.60.110.10 1 318 1.4E-81 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS00135 4c1c739aae2a9e709d6dc2199b4e70fe 325 SUPERFAMILY SSF56317 6 301 4.97E-72 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS00135 4c1c739aae2a9e709d6dc2199b4e70fe 325 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 164 177 - T 29-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 CVS48_RS00135 4c1c739aae2a9e709d6dc2199b4e70fe 325 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 39 54 - T 29-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 CVS48_RS23695 0710c4cdd34d6851600910d457af6ae7 477 Gene3D G3DSA:3.40.640.10 125 370 9.3E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS23695 0710c4cdd34d6851600910d457af6ae7 477 SUPERFAMILY SSF46785 4 66 4.21E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23695 0710c4cdd34d6851600910d457af6ae7 477 Pfam PF00155 Aminotransferase class I and II 141 435 6.6E-20 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS23695 0710c4cdd34d6851600910d457af6ae7 477 Gene3D G3DSA:3.90.1150.10 371 472 5.8E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS23695 0710c4cdd34d6851600910d457af6ae7 477 SMART SM00345 5 64 1.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS23695 0710c4cdd34d6851600910d457af6ae7 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 64 2.6E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS23695 0710c4cdd34d6851600910d457af6ae7 477 Gene3D G3DSA:1.10.10.10 1 66 7.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23695 0710c4cdd34d6851600910d457af6ae7 477 SUPERFAMILY SSF53383 112 469 6.74E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS23930 477d61174a27317a119e2113e2de282d 481 SUPERFAMILY SSF56954 12 475 9.81E-119 T 29-03-2018 CVS48_RS23930 477d61174a27317a119e2113e2de282d 481 Gene3D G3DSA:1.20.1600.10 28 479 2.0E-105 T 29-03-2018 CVS48_RS23930 477d61174a27317a119e2113e2de282d 481 Pfam PF02321 Outer membrane efflux protein 73 263 9.0E-27 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS23930 477d61174a27317a119e2113e2de282d 481 Pfam PF02321 Outer membrane efflux protein 292 471 3.7E-31 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS23930 477d61174a27317a119e2113e2de282d 481 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 19 473 6.1E-127 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 SUPERFAMILY SSF81767 226 368 9.94E-42 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 PRINTS PR00906 SecA protein signature 100 114 2.5E-72 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 PRINTS PR00906 SecA protein signature 116 126 2.5E-72 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 PRINTS PR00906 SecA protein signature 413 426 2.5E-72 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 PRINTS PR00906 SecA protein signature 169 189 2.5E-72 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 PRINTS PR00906 SecA protein signature 62 86 2.5E-72 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 PRINTS PR00906 SecA protein signature 339 361 2.5E-72 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 PRINTS PR00906 SecA protein signature 376 393 2.5E-72 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 Gene3D G3DSA:3.40.50.300 8 259 1.5E-52 T 29-03-2018 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 Gene3D G3DSA:3.40.50.300 299 416 6.2E-9 T 29-03-2018 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 Gene3D G3DSA:3.40.50.300 417 654 6.8E-58 T 29-03-2018 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 839 19.99 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 Pfam PF07517 SecA DEAD-like domain 5 402 9.8E-130 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 825 0.0 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 SUPERFAMILY SSF52540 416 625 1.46E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 Pfam PF07516 SecA Wing and Scaffold domain 624 836 2.9E-67 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 SMART SM00957 5 402 2.5E-300 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 SUPERFAMILY SSF81886 887 899 6.15E-81 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 SUPERFAMILY SSF81886 628 847 6.15E-81 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 Pfam PF02810 SEC-C motif 891 909 1.8E-10 T 29-03-2018 IPR004027 SEC-C motif CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 Pfam PF01043 SecA preprotein cross-linking domain 232 358 5.4E-35 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 SUPERFAMILY SSF52540 368 415 7.22E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 SUPERFAMILY SSF52540 4 227 7.22E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 Gene3D G3DSA:1.10.3060.10 655 838 3.2E-55 T 29-03-2018 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 SMART SM00958 227 358 2.4E-74 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CVS48_RS02425 2fa6c61d6eaff3817ce2643141b1e9cf 911 ProSitePatterns PS01312 SecA family signature. 500 515 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CVS48_RS18175 ea5e4a1eb1340a82eb9a8ada9eecd6a2 629 Gene3D G3DSA:2.30.40.10 4 73 2.7E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS18175 ea5e4a1eb1340a82eb9a8ada9eecd6a2 629 SUPERFAMILY SSF51338 4 66 1.47E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS18175 ea5e4a1eb1340a82eb9a8ada9eecd6a2 629 SUPERFAMILY SSF51338 497 543 1.47E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS18175 ea5e4a1eb1340a82eb9a8ada9eecd6a2 629 Pfam PF07969 Amidohydrolase family 54 537 4.3E-118 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS18175 ea5e4a1eb1340a82eb9a8ada9eecd6a2 629 SUPERFAMILY SSF51556 65 127 1.15E-41 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS18175 ea5e4a1eb1340a82eb9a8ada9eecd6a2 629 SUPERFAMILY SSF51556 207 498 1.15E-41 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS18175 ea5e4a1eb1340a82eb9a8ada9eecd6a2 629 Gene3D G3DSA:3.20.20.140 74 492 6.5E-34 T 29-03-2018 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 SUPERFAMILY SSF50494 57 282 1.38E-63 T 29-03-2018 IPR009003 Peptidase S1, PA clan CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 Gene3D G3DSA:2.30.42.10 281 386 2.4E-26 T 29-03-2018 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 Gene3D G3DSA:2.40.10.10 162 275 1.8E-40 T 29-03-2018 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 Pfam PF13365 Trypsin-like peptidase domain 112 247 1.0E-34 T 29-03-2018 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 PRINTS PR00834 HtrA/DegQ protease family signature 218 235 8.5E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 PRINTS PR00834 HtrA/DegQ protease family signature 121 133 8.5E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 PRINTS PR00834 HtrA/DegQ protease family signature 183 207 8.5E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 PRINTS PR00834 HtrA/DegQ protease family signature 327 339 8.5E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 PRINTS PR00834 HtrA/DegQ protease family signature 142 162 8.5E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 8.5E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 SMART SM00228 286 369 1.7E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 Pfam PF13180 PDZ domain 287 377 4.9E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 SUPERFAMILY SSF50156 244 370 3.15E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS05165 2d1371e37bb82fd3e5636fcf671f2a76 386 Gene3D G3DSA:2.40.10.10 56 161 3.5E-29 T 29-03-2018 CVS48_RS07110 31e389de4baa6f9d02fcb4b71350b176 371 Gene3D G3DSA:3.40.50.2000 167 344 8.1E-44 T 29-03-2018 CVS48_RS07110 31e389de4baa6f9d02fcb4b71350b176 371 Pfam PF13477 Glycosyl transferase 4-like 2 132 1.5E-29 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS07110 31e389de4baa6f9d02fcb4b71350b176 371 SUPERFAMILY SSF53756 13 361 2.65E-70 T 29-03-2018 CVS48_RS07110 31e389de4baa6f9d02fcb4b71350b176 371 Gene3D G3DSA:3.40.50.2000 3 166 1.3E-14 T 29-03-2018 CVS48_RS07110 31e389de4baa6f9d02fcb4b71350b176 371 Pfam PF00534 Glycosyl transferases group 1 171 337 1.7E-40 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS09835 585990a02a2b1ee192839ed359207683 86 Gene3D G3DSA:2.30.170.10 47 85 4.0E-5 T 29-03-2018 CVS48_RS15710 0574f2228f76b64cd85ec8a427fd9a1c 155 Pfam PF03918 Cytochrome C biogenesis protein 23 151 1.9E-46 T 29-03-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family CVS48_RS19155 0adffaf6db22a8ca57b9fab1f5b27feb 293 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 223 1.9E-50 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CVS48_RS19155 0adffaf6db22a8ca57b9fab1f5b27feb 293 SUPERFAMILY SSF51621 5 233 2.26E-68 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS19155 0adffaf6db22a8ca57b9fab1f5b27feb 293 Gene3D G3DSA:3.20.20.60 2 235 2.8E-58 T 29-03-2018 CVS48_RS19155 0adffaf6db22a8ca57b9fab1f5b27feb 293 PIRSF PIRSF015582 1 293 9.9E-81 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like CVS48_RS27045 f67b60be0441a4b2772ba32d13cfbd16 381 Pfam PF00355 Rieske [2Fe-2S] domain 43 136 6.9E-9 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS27045 f67b60be0441a4b2772ba32d13cfbd16 381 SUPERFAMILY SSF50022 7 156 3.54E-28 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS27045 f67b60be0441a4b2772ba32d13cfbd16 381 Gene3D G3DSA:3.90.380.10 140 380 4.4E-33 T 29-03-2018 CVS48_RS27045 f67b60be0441a4b2772ba32d13cfbd16 381 Gene3D G3DSA:2.20.25.10 79 139 3.7E-17 T 29-03-2018 CVS48_RS27045 f67b60be0441a4b2772ba32d13cfbd16 381 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 177 379 5.6E-35 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CVS48_RS27045 f67b60be0441a4b2772ba32d13cfbd16 381 SUPERFAMILY SSF55961 162 378 5.18E-46 T 29-03-2018 CVS48_RS09180 c02264301141e3cb253eeb3c3f33406c 346 SUPERFAMILY SSF102198 95 118 5.62E-13 T 29-03-2018 CVS48_RS09180 c02264301141e3cb253eeb3c3f33406c 346 SUPERFAMILY SSF102198 167 345 5.62E-13 T 29-03-2018 CVS48_RS09180 c02264301141e3cb253eeb3c3f33406c 346 Pfam PF04199 Putative cyclase 89 274 1.3E-13 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CVS48_RS09180 c02264301141e3cb253eeb3c3f33406c 346 Gene3D G3DSA:3.50.30.50 40 346 2.2E-45 T 29-03-2018 CVS48_RS28600 6e62eaed5dcbf616a658324558233e80 172 Pfam PF02627 Carboxymuconolactone decarboxylase family 97 169 5.6E-13 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS28600 6e62eaed5dcbf616a658324558233e80 172 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 172 71.178 T 29-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS28600 6e62eaed5dcbf616a658324558233e80 172 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 109 158 4.5E-10 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS28600 6e62eaed5dcbf616a658324558233e80 172 SUPERFAMILY SSF69118 4 169 2.52E-38 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS28600 6e62eaed5dcbf616a658324558233e80 172 Gene3D G3DSA:1.20.1290.10 2 171 1.4E-30 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS00910 414c8b0e2aee1afde8362aff5e4ae6cc 166 Pfam PF01252 Signal peptidase (SPase) II 15 153 7.7E-35 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS00910 414c8b0e2aee1afde8362aff5e4ae6cc 166 TIGRFAM TIGR00077 lspA: signal peptidase II 11 157 3.9E-37 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS00910 414c8b0e2aee1afde8362aff5e4ae6cc 166 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 52 60 2.4E-15 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS00910 414c8b0e2aee1afde8362aff5e4ae6cc 166 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 134 150 2.4E-15 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS00910 414c8b0e2aee1afde8362aff5e4ae6cc 166 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 98 113 2.4E-15 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS00910 414c8b0e2aee1afde8362aff5e4ae6cc 166 ProSitePatterns PS00855 Signal peptidases II signature. 101 113 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS00910 414c8b0e2aee1afde8362aff5e4ae6cc 166 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 6 159 15.284 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 SUPERFAMILY SSF55781 66 206 2.16E-6 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 Pfam PF01590 GAF domain 72 202 3.5E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 Pfam PF02954 Bacterial regulatory protein, Fis family 614 643 6.5E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 Gene3D G3DSA:3.40.50.300 203 543 1.5E-28 T 29-03-2018 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 613 630 1.3E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 630 650 1.3E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 SUPERFAMILY SSF52540 340 561 4.37E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 Pfam PF00158 Sigma-54 interaction domain 336 490 1.3E-55 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 Gene3D G3DSA:1.10.10.60 556 653 8.8E-13 T 29-03-2018 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 SUPERFAMILY SSF46689 602 649 2.69E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 Gene3D G3DSA:3.30.450.40 139 202 1.3E-6 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 Gene3D G3DSA:3.30.450.40 59 138 0.2 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 347 360 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CVS48_RS04255 ccf142f492ada39135b7746d9e496ec6 653 SMART SM00382 343 487 6.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28480 3993068679402b52b9e4999b9b877ee5 295 Gene3D G3DSA:1.10.3470.10 4 288 2.3E-45 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS28480 3993068679402b52b9e4999b9b877ee5 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 283 5.3E-41 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS15090 c7561ae910e7d93417e00b0de1c1ba6b 524 SUPERFAMILY SSF53850 29 523 2.9E-131 T 29-03-2018 CVS48_RS15090 c7561ae910e7d93417e00b0de1c1ba6b 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 436 5.1E-89 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS15090 c7561ae910e7d93417e00b0de1c1ba6b 524 Gene3D G3DSA:3.40.190.10 152 294 9.2E-44 T 29-03-2018 CVS48_RS15090 c7561ae910e7d93417e00b0de1c1ba6b 524 Gene3D G3DSA:3.10.105.10 295 491 5.6E-45 T 29-03-2018 CVS48_RS15090 c7561ae910e7d93417e00b0de1c1ba6b 524 Gene3D G3DSA:3.90.76.10 56 151 1.2E-30 T 29-03-2018 CVS48_RS15090 c7561ae910e7d93417e00b0de1c1ba6b 524 PIRSF PIRSF002741 4 524 2.4E-148 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS05950 f7710fcee39f62d04b49e1e3522d86b2 280 Gene3D G3DSA:1.10.10.10 5 85 2.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05950 f7710fcee39f62d04b49e1e3522d86b2 280 SUPERFAMILY SSF46785 16 85 1.73E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05950 f7710fcee39f62d04b49e1e3522d86b2 280 SMART SM00346 13 105 3.4E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS05950 f7710fcee39f62d04b49e1e3522d86b2 280 Gene3D G3DSA:3.30.450.40 88 266 1.7E-32 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS05950 f7710fcee39f62d04b49e1e3522d86b2 280 Pfam PF09339 IclR helix-turn-helix domain 16 65 1.1E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS05950 f7710fcee39f62d04b49e1e3522d86b2 280 SUPERFAMILY SSF55781 88 260 3.34E-34 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS05950 f7710fcee39f62d04b49e1e3522d86b2 280 Pfam PF01614 Bacterial transcriptional regulator 139 256 5.5E-13 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS14350 c19d52e2696e1777af3748e3fe799443 243 Gene3D G3DSA:1.10.10.200 1 78 1.3E-33 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CVS48_RS14350 c19d52e2696e1777af3748e3fe799443 243 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 5.1E-92 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS14350 c19d52e2696e1777af3748e3fe799443 243 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 34.513 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS14350 c19d52e2696e1777af3748e3fe799443 243 Pfam PF01709 Transcriptional regulator 5 236 9.9E-96 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS14350 c19d52e2696e1777af3748e3fe799443 243 SUPERFAMILY SSF75625 3 240 2.09E-94 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS14350 c19d52e2696e1777af3748e3fe799443 243 Gene3D G3DSA:3.30.70.980 83 177 1.5E-31 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS14350 c19d52e2696e1777af3748e3fe799443 243 Gene3D G3DSA:3.30.70.980 178 243 4.3E-10 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS08850 b336875a071d5d3cfd61201952dd19a0 348 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 35 344 1.5E-108 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CVS48_RS08850 b336875a071d5d3cfd61201952dd19a0 348 Gene3D G3DSA:2.40.50.140 272 338 3.7E-8 T 29-03-2018 CVS48_RS08850 b336875a071d5d3cfd61201952dd19a0 348 Pfam PF08402 TOBE domain 269 346 6.1E-19 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS08850 b336875a071d5d3cfd61201952dd19a0 348 SUPERFAMILY SSF52540 4 241 1.08E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08850 b336875a071d5d3cfd61201952dd19a0 348 SUPERFAMILY SSF50331 237 345 8.22E-16 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS08850 b336875a071d5d3cfd61201952dd19a0 348 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS08850 b336875a071d5d3cfd61201952dd19a0 348 Gene3D G3DSA:3.40.50.300 1 257 4.1E-77 T 29-03-2018 CVS48_RS08850 b336875a071d5d3cfd61201952dd19a0 348 SMART SM00382 28 212 1.7E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08850 b336875a071d5d3cfd61201952dd19a0 348 Pfam PF00005 ABC transporter 20 161 1.8E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS27515 2c8b14af5ef959adc537bd196723da15 373 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 371 60.098 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CVS48_RS27515 2c8b14af5ef959adc537bd196723da15 373 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 13 369 2.4E-101 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CVS48_RS27515 2c8b14af5ef959adc537bd196723da15 373 Gene3D G3DSA:3.40.640.10 53 263 2.4E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS27515 2c8b14af5ef959adc537bd196723da15 373 SUPERFAMILY SSF53383 19 371 1.1E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS27515 2c8b14af5ef959adc537bd196723da15 373 Gene3D G3DSA:3.90.1150.10 264 366 1.2E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS27515 2c8b14af5ef959adc537bd196723da15 373 Pfam PF00155 Aminotransferase class I and II 40 364 1.8E-48 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS27515 2c8b14af5ef959adc537bd196723da15 373 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 232 241 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CVS48_RS22690 88b12097526affa39a4f3967439a46eb 406 Pfam PF06792 Uncharacterised protein family (UPF0261) 7 403 1.4E-159 T 29-03-2018 IPR008322 Uncharacterised protein family UPF0261 CVS48_RS22690 88b12097526affa39a4f3967439a46eb 406 Gene3D G3DSA:3.40.50.1820 9 376 1.7E-4 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS22690 88b12097526affa39a4f3967439a46eb 406 PIRSF PIRSF033271 4 406 2.8E-180 T 29-03-2018 IPR008322 Uncharacterised protein family UPF0261 CVS48_RS22690 88b12097526affa39a4f3967439a46eb 406 Hamap MF_00677 UPF0261 protein . 5 406 49.983 T 29-03-2018 IPR008322 Uncharacterised protein family UPF0261 CVS48_RS21550 68f6a983ba42268c8847d3358fa0a98e 324 Gene3D G3DSA:3.40.190.10 125 280 3.4E-12 T 29-03-2018 CVS48_RS21550 68f6a983ba42268c8847d3358fa0a98e 324 PIRSF PIRSF017082 1 324 3.6E-68 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21550 68f6a983ba42268c8847d3358fa0a98e 324 SUPERFAMILY SSF53850 107 288 6.76E-14 T 29-03-2018 CVS48_RS21550 68f6a983ba42268c8847d3358fa0a98e 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 318 1.6E-72 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS19215 2b3883fd13f21e0081e77c14bc0a4836 170 SMART SM00953 21 157 2.7E-26 T 29-03-2018 IPR014914 RES domain CVS48_RS19215 2b3883fd13f21e0081e77c14bc0a4836 170 Pfam PF08808 RES domain 7 163 8.3E-22 T 29-03-2018 IPR014914 RES domain CVS48_RS24460 ef24543c2ab3f5df5de35eb411b34284 415 SMART SM00382 58 243 6.7E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS24460 ef24543c2ab3f5df5de35eb411b34284 415 Gene3D G3DSA:3.40.50.300 50 281 2.2E-17 T 29-03-2018 CVS48_RS24460 ef24543c2ab3f5df5de35eb411b34284 415 SUPERFAMILY SSF52540 48 257 4.7E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS24460 ef24543c2ab3f5df5de35eb411b34284 415 Pfam PF13481 AAA domain 38 214 9.7E-36 T 29-03-2018 CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 PIRSF PIRSF002888 3 331 5.0E-94 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 SUPERFAMILY SSF101801 251 325 1.83E-12 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 Gene3D G3DSA:3.40.1550.10 47 234 2.4E-38 T 29-03-2018 IPR028976 CheC-like domain CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 4.1E-27 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 4.1E-27 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 213 231 4.1E-27 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 4.1E-27 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 SUPERFAMILY SSF103039 51 231 8.37E-20 T 29-03-2018 IPR028976 CheC-like domain CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 6 322 1.7E-103 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 321 1.5E-17 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 Pfam PF02154 Flagellar motor switch protein FliM 39 231 1.2E-71 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CVS48_RS16965 e837b3b206e295fd5e0450634593159b 335 Gene3D G3DSA:2.30.330.10 240 331 3.1E-16 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 Pfam PF00361 Proton-conducting membrane transporter 126 399 2.1E-66 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 819 940 1.5E-30 T 29-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 113 8.2E-9 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 Pfam PF13244 Domain of unknown function (DUF4040) 616 679 5.6E-19 T 29-03-2018 IPR025383 Domain of unknown function DUF4040 CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 9.9E-40 T 29-03-2018 CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 9.9E-40 T 29-03-2018 CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 9.9E-40 T 29-03-2018 CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 9.9E-40 T 29-03-2018 CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 9.9E-40 T 29-03-2018 CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 9.9E-40 T 29-03-2018 CVS48_RS19930 39f13a5696e047651aec5a54df5cfcd6 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 9.9E-40 T 29-03-2018 CVS48_RS16035 5ef7c3bdecf8e48e086ed726834bfdc8 194 Gene3D G3DSA:3.40.630.30 5 174 2.1E-38 T 29-03-2018 CVS48_RS16035 5ef7c3bdecf8e48e086ed726834bfdc8 194 SUPERFAMILY SSF55729 6 166 4.36E-44 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS16035 5ef7c3bdecf8e48e086ed726834bfdc8 194 Pfam PF13302 Acetyltransferase (GNAT) domain 8 142 5.0E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS20995 b56aa2dccd1c9fcecf95a27bd75dcc98 398 Gene3D G3DSA:3.40.50.1820 112 392 1.1E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS20995 b56aa2dccd1c9fcecf95a27bd75dcc98 398 SUPERFAMILY SSF53474 130 323 1.38E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS20995 b56aa2dccd1c9fcecf95a27bd75dcc98 398 SUPERFAMILY SSF53474 350 392 1.38E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS20995 b56aa2dccd1c9fcecf95a27bd75dcc98 398 Pfam PF10503 Esterase PHB depolymerase 133 328 1.5E-66 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CVS48_RS20995 b56aa2dccd1c9fcecf95a27bd75dcc98 398 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 134 317 3.8E-44 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CVS48_RS09895 8e0d4da3d732091a4c5f58c9dfb527cc 432 SUPERFAMILY SSF54373 283 368 4.97E-10 T 29-03-2018 CVS48_RS09895 8e0d4da3d732091a4c5f58c9dfb527cc 432 SUPERFAMILY SSF51905 16 67 5.57E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09895 8e0d4da3d732091a4c5f58c9dfb527cc 432 SUPERFAMILY SSF51905 119 281 5.57E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09895 8e0d4da3d732091a4c5f58c9dfb527cc 432 SUPERFAMILY SSF51905 368 426 5.57E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09895 8e0d4da3d732091a4c5f58c9dfb527cc 432 Gene3D G3DSA:3.50.50.60 5 427 2.3E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09895 8e0d4da3d732091a4c5f58c9dfb527cc 432 Pfam PF01266 FAD dependent oxidoreductase 17 407 1.2E-46 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS20020 2bec24fa547b49aad39174657336e1b3 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 280 1.1E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20020 2bec24fa547b49aad39174657336e1b3 296 Gene3D G3DSA:1.10.3720.10 7 286 3.0E-38 T 29-03-2018 CVS48_RS20020 2bec24fa547b49aad39174657336e1b3 296 SUPERFAMILY SSF161098 50 275 1.07E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 Gene3D G3DSA:3.30.70.1170 188 243 9.4E-17 T 29-03-2018 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 Gene3D G3DSA:1.10.287.730 161 186 5.1E-8 T 29-03-2018 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 Gene3D G3DSA:1.10.940.10 20 160 1.3E-18 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 331 342 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 426 443 1.5E-22 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 264 274 1.5E-22 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 235 249 1.5E-22 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 382 398 1.5E-22 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 332 344 1.5E-22 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 Pfam PF01189 16S rRNA methyltransferase RsmB/F 254 441 3.2E-49 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 Gene3D G3DSA:3.40.50.150 244 445 4.5E-49 T 29-03-2018 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 SUPERFAMILY SSF48013 33 164 7.85E-9 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 108 444 5.2E-86 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS07935 e29e7c807ca10bc473aaeba168f39dc5 445 SUPERFAMILY SSF53335 156 443 9.88E-68 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS22870 4a6c97c6dbb1c593ae18bdcf5f2ee3d6 431 Pfam PF01554 MatE 224 384 2.8E-9 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS22870 4a6c97c6dbb1c593ae18bdcf5f2ee3d6 431 Pfam PF01554 MatE 8 164 4.0E-15 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS21740 b319eeef82da1c8f9c84b5b0da0de583 405 Gene3D G3DSA:1.20.1250.20 199 405 6.2E-21 T 29-03-2018 CVS48_RS21740 b319eeef82da1c8f9c84b5b0da0de583 405 SUPERFAMILY SSF103473 6 392 9.55E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS21740 b319eeef82da1c8f9c84b5b0da0de583 405 Gene3D G3DSA:1.20.1250.20 9 198 5.6E-33 T 29-03-2018 CVS48_RS21740 b319eeef82da1c8f9c84b5b0da0de583 405 Pfam PF07690 Major Facilitator Superfamily 18 231 1.3E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS10440 31925e29222cd354165d6e91fd56ff73 297 Gene3D G3DSA:1.10.3470.10 1 287 4.0E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS10440 31925e29222cd354165d6e91fd56ff73 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 282 2.1E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 Gene3D G3DSA:1.20.120.530 101 254 3.4E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 SMART SM00895 116 243 4.3E-23 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 SMART SM00345 35 94 2.3E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 8.9E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 8.9E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 SUPERFAMILY SSF46785 26 98 3.21E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 94 6.4E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 Gene3D G3DSA:1.10.10.10 5 96 9.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 Pfam PF07729 FCD domain 118 241 2.2E-27 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS13955 d2017df1bb6d3d8723f3b5de7fa776ed 261 SUPERFAMILY SSF48008 113 250 1.36E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS06215 55ae31b887cd880c5b37631b383d8ae3 387 Gene3D G3DSA:1.20.1090.10 191 387 1.5E-54 T 29-03-2018 CVS48_RS06215 55ae31b887cd880c5b37631b383d8ae3 387 Gene3D G3DSA:3.40.50.1970 11 190 7.2E-46 T 29-03-2018 CVS48_RS06215 55ae31b887cd880c5b37631b383d8ae3 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 180 208 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CVS48_RS06215 55ae31b887cd880c5b37631b383d8ae3 387 SUPERFAMILY SSF56796 6 385 1.09E-120 T 29-03-2018 CVS48_RS06215 55ae31b887cd880c5b37631b383d8ae3 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 374 3.8E-114 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CVS48_RS06730 535555351b8e70f99c363c24b064301c 238 PIRSF PIRSF029287 4 238 8.6E-72 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 CVS48_RS06730 535555351b8e70f99c363c24b064301c 238 Gene3D G3DSA:3.40.1730.10 8 237 5.1E-66 T 29-03-2018 CVS48_RS06730 535555351b8e70f99c363c24b064301c 238 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 11 145 5.4E-40 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 CVS48_RS06730 535555351b8e70f99c363c24b064301c 238 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 11 144 4.1E-45 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 124 4.4E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 Gene3D G3DSA:1.20.140.10 228 387 2.3E-48 T 29-03-2018 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 SUPERFAMILY SSF56645 11 249 1.11E-80 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 SUPERFAMILY SSF47203 236 385 4.35E-45 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 224 7.3E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 3.4E-41 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 Gene3D G3DSA:2.40.110.10 127 227 3.6E-39 T 29-03-2018 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 Gene3D G3DSA:1.10.540.10 5 126 6.8E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS25880 0a1f974d6e9b48bef7a7b5c431396eba 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS03185 8ce96ad2ec317af759d239656435e927 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 125 2.4E-17 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CVS48_RS03185 8ce96ad2ec317af759d239656435e927 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 80 93 2.4E-17 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CVS48_RS03185 8ce96ad2ec317af759d239656435e927 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 97 111 2.4E-17 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CVS48_RS03185 8ce96ad2ec317af759d239656435e927 151 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 150 3.5E-53 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CVS48_RS03185 8ce96ad2ec317af759d239656435e927 151 Gene3D G3DSA:2.40.50.100 4 151 8.8E-21 T 29-03-2018 CVS48_RS03185 8ce96ad2ec317af759d239656435e927 151 SUPERFAMILY SSF51230 75 150 1.96E-25 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS03185 8ce96ad2ec317af759d239656435e927 151 Pfam PF00364 Biotin-requiring enzyme 77 150 7.1E-25 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS03185 8ce96ad2ec317af759d239656435e927 151 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 107 124 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 SUPERFAMILY SSF52374 116 454 1.31E-81 T 29-03-2018 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 Gene3D G3DSA:3.40.50.620 108 377 1.5E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 311 332 4.4E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 121 136 4.4E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 136 152 4.4E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 160 173 4.4E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 Gene3D G3DSA:3.30.1360.70 1 107 1.2E-29 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 6 561 9.8E-125 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 SUPERFAMILY SSF55190 8 103 5.1E-20 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 Pfam PF05746 DALR anticodon binding domain 444 561 4.2E-33 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 Hamap MF_00123 Arginine--tRNA ligase [argS]. 11 561 25.205 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 SUPERFAMILY SSF47323 439 561 5.17E-36 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 Pfam PF00750 tRNA synthetases class I (R) 108 406 4.1E-22 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 131 140 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 SMART SM01016 7 93 3.2E-35 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 Gene3D G3DSA:1.10.730.10 410 561 5.5E-45 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 93 1.4E-22 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CVS48_RS05450 382d4890816d29c87088f0de74a698da 561 SMART SM00836 444 561 2.5E-51 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CVS48_RS11990 a8420bef670c87a97be2e5320139dfb5 349 PRINTS PR00069 Aldo-keto reductase signature 119 137 9.6E-9 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS11990 a8420bef670c87a97be2e5320139dfb5 349 PRINTS PR00069 Aldo-keto reductase signature 167 184 9.6E-9 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS11990 a8420bef670c87a97be2e5320139dfb5 349 SUPERFAMILY SSF51430 1 348 7.73E-108 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS11990 a8420bef670c87a97be2e5320139dfb5 349 Pfam PF00248 Aldo/keto reductase family 16 340 3.5E-72 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS11990 a8420bef670c87a97be2e5320139dfb5 349 Gene3D G3DSA:3.20.20.100 1 349 2.3E-94 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS26350 4f99dda91785aae14b5203c4adb382e7 283 SUPERFAMILY SSF53474 29 278 2.41E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS26350 4f99dda91785aae14b5203c4adb382e7 283 Gene3D G3DSA:3.40.50.1820 28 280 9.8E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS26350 4f99dda91785aae14b5203c4adb382e7 283 Pfam PF12146 Serine aminopeptidase, S33 51 155 1.2E-11 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CVS48_RS01175 2a9d42ec18a6c1f86eb741eab9efa9ab 425 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 12 425 50.56 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CVS48_RS01175 2a9d42ec18a6c1f86eb741eab9efa9ab 425 Gene3D G3DSA:3.90.1150.10 280 425 2.4E-54 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS01175 2a9d42ec18a6c1f86eb741eab9efa9ab 425 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 227 243 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CVS48_RS01175 2a9d42ec18a6c1f86eb741eab9efa9ab 425 SUPERFAMILY SSF53383 5 425 8.11E-173 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS01175 2a9d42ec18a6c1f86eb741eab9efa9ab 425 PIRSF PIRSF000412 3 425 2.7E-163 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CVS48_RS01175 2a9d42ec18a6c1f86eb741eab9efa9ab 425 Gene3D G3DSA:3.40.640.10 42 279 1.5E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS01175 2a9d42ec18a6c1f86eb741eab9efa9ab 425 Pfam PF00464 Serine hydroxymethyltransferase 14 390 5.1E-167 T 29-03-2018 CVS48_RS08540 4fe7e45c05a11b286abdc2df1e078086 347 Pfam PF06996 Type VI secretion, TssG 24 312 3.0E-82 T 29-03-2018 IPR010732 Type VI secretion, TssG-like CVS48_RS08540 4fe7e45c05a11b286abdc2df1e078086 347 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 24 312 5.4E-79 T 29-03-2018 IPR010732 Type VI secretion, TssG-like CVS48_RS03530 3338820e41f6c4e764528fdad89e31c8 315 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 38 312 2.0E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS03530 3338820e41f6c4e764528fdad89e31c8 315 PIRSF PIRSF017082 1 315 6.8E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS03530 3338820e41f6c4e764528fdad89e31c8 315 Gene3D G3DSA:3.40.190.10 114 246 6.2E-10 T 29-03-2018 CVS48_RS03530 3338820e41f6c4e764528fdad89e31c8 315 SUPERFAMILY SSF53850 105 277 3.94E-10 T 29-03-2018 CVS48_RS02430 dc1f863fd0f7619156dcb7e57d32761f 328 Gene3D G3DSA:2.70.70.10 150 312 1.7E-44 T 29-03-2018 CVS48_RS02430 dc1f863fd0f7619156dcb7e57d32761f 328 Pfam PF01551 Peptidase family M23 209 303 5.2E-33 T 29-03-2018 IPR016047 Peptidase M23 CVS48_RS02430 dc1f863fd0f7619156dcb7e57d32761f 328 SUPERFAMILY SSF51261 166 307 5.23E-56 T 29-03-2018 IPR011055 Duplicated hybrid motif CVS48_RS17975 1d9f6093c68865a023b27fda11bacd53 297 SUPERFAMILY SSF56281 37 255 7.42E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS17975 1d9f6093c68865a023b27fda11bacd53 297 SMART SM00849 47 232 5.0E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS17975 1d9f6093c68865a023b27fda11bacd53 297 Pfam PF00753 Metallo-beta-lactamase superfamily 46 232 1.6E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS17975 1d9f6093c68865a023b27fda11bacd53 297 Gene3D G3DSA:3.60.15.10 23 261 4.6E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 SUPERFAMILY SSF56601 231 253 7.04E-117 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 SUPERFAMILY SSF56601 445 757 7.04E-117 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 SUPERFAMILY SSF56601 286 337 7.04E-117 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 Pfam PF17092 Penicillin-binding protein OB-like domain 340 448 4.6E-16 T 29-03-2018 IPR031376 Penicillin-binding protein, OB-like domain CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 Gene3D G3DSA:3.40.710.10 262 750 7.0E-116 T 29-03-2018 CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 SUPERFAMILY SSF53955 62 271 2.73E-74 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 Pfam PF00905 Penicillin binding protein transpeptidase domain 451 726 5.1E-38 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 Gene3D G3DSA:1.10.3810.10 68 261 5.4E-76 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 85 735 1.2E-178 T 29-03-2018 CVS48_RS06755 6e9064327069c74bd65b558b9ace3a54 816 Pfam PF00912 Transglycosylase 77 249 4.0E-61 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CVS48_RS16455 5df0ee420f6fcd990577e6c283b0f838 587 SMART SM00382 324 486 3.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16455 5df0ee420f6fcd990577e6c283b0f838 587 Gene3D G3DSA:3.40.50.300 311 486 7.7E-23 T 29-03-2018 CVS48_RS16455 5df0ee420f6fcd990577e6c283b0f838 587 SUPERFAMILY SSF52540 307 487 3.95E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16455 5df0ee420f6fcd990577e6c283b0f838 587 Pfam PF07728 AAA domain (dynein-related subfamily) 327 480 9.4E-27 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CVS48_RS07380 97faf5d5975294da223f93173bbbf5d8 327 SUPERFAMILY SSF53850 114 291 8.14E-6 T 29-03-2018 CVS48_RS07380 97faf5d5975294da223f93173bbbf5d8 327 PIRSF PIRSF017082 1 327 8.4E-75 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS07380 97faf5d5975294da223f93173bbbf5d8 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 9.4E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS07380 97faf5d5975294da223f93173bbbf5d8 327 Gene3D G3DSA:3.40.190.10 125 236 4.4E-6 T 29-03-2018 CVS48_RS10485 ff55343ec6ca0c251f22964e9f28e558 176 Pfam PF03724 META domain 46 167 7.6E-24 T 29-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ CVS48_RS08600 953adedd0f8b93d5c8de8977b4fb006f 323 SMART SM00422 18 95 3.5E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS08600 953adedd0f8b93d5c8de8977b4fb006f 323 Gene3D G3DSA:1.10.1660.10 18 303 1.8E-24 T 29-03-2018 CVS48_RS08600 953adedd0f8b93d5c8de8977b4fb006f 323 Pfam PF13411 MerR HTH family regulatory protein 18 78 3.0E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS08600 953adedd0f8b93d5c8de8977b4fb006f 323 SUPERFAMILY SSF46955 18 84 1.14E-14 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS05800 b9d0e333862b7be1f9c04f40b77223e0 308 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 301 2.4E-23 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CVS48_RS05800 b9d0e333862b7be1f9c04f40b77223e0 308 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 6 304 8.2E-55 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CVS48_RS05800 b9d0e333862b7be1f9c04f40b77223e0 308 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 150 8.6E-35 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CVS48_RS05800 b9d0e333862b7be1f9c04f40b77223e0 308 Gene3D G3DSA:3.40.50.720 1 179 9.1E-28 T 29-03-2018 CVS48_RS05800 b9d0e333862b7be1f9c04f40b77223e0 308 Gene3D G3DSA:1.10.1040.10 180 308 6.7E-27 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS05800 b9d0e333862b7be1f9c04f40b77223e0 308 SUPERFAMILY SSF48179 178 302 6.46E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS05800 b9d0e333862b7be1f9c04f40b77223e0 308 SUPERFAMILY SSF51735 1 152 2.15E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS05155 182f0cc62a622a859945149698dc2e53 263 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 16 234 4.8E-67 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CVS48_RS05155 182f0cc62a622a859945149698dc2e53 263 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 7 248 18.681 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CVS48_RS05155 182f0cc62a622a859945149698dc2e53 263 Pfam PF00902 Sec-independent protein translocase protein (TatC) 18 229 1.7E-64 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CVS48_RS05155 182f0cc62a622a859945149698dc2e53 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 14 41 5.4E-48 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CVS48_RS05155 182f0cc62a622a859945149698dc2e53 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 162 190 5.4E-48 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CVS48_RS05155 182f0cc62a622a859945149698dc2e53 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 111 137 5.4E-48 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CVS48_RS05155 182f0cc62a622a859945149698dc2e53 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 93 111 5.4E-48 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CVS48_RS22405 d8b55ef0a852e7dc97d413f2591575aa 739 Pfam PF00905 Penicillin binding protein transpeptidase domain 327 555 5.5E-18 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CVS48_RS22405 d8b55ef0a852e7dc97d413f2591575aa 739 Pfam PF00912 Transglycosylase 70 241 1.1E-45 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CVS48_RS22405 d8b55ef0a852e7dc97d413f2591575aa 739 Gene3D G3DSA:1.10.3810.10 52 258 4.8E-54 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CVS48_RS22405 d8b55ef0a852e7dc97d413f2591575aa 739 SUPERFAMILY SSF53955 52 272 1.46E-59 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS22405 d8b55ef0a852e7dc97d413f2591575aa 739 Gene3D G3DSA:3.40.710.10 269 633 2.7E-68 T 29-03-2018 CVS48_RS22405 d8b55ef0a852e7dc97d413f2591575aa 739 SUPERFAMILY SSF56601 223 650 4.59E-96 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS22405 d8b55ef0a852e7dc97d413f2591575aa 739 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 648 732 1.3E-16 T 29-03-2018 IPR009647 Penicillin-binding, C-terminal CVS48_RS22405 d8b55ef0a852e7dc97d413f2591575aa 739 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 52 646 5.5E-230 T 29-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 CVS48_RS26320 9d3608a1a0b178413aa3be45a8d69801 525 Gene3D G3DSA:3.10.105.10 287 497 1.3E-41 T 29-03-2018 CVS48_RS26320 9d3608a1a0b178413aa3be45a8d69801 525 Gene3D G3DSA:3.40.190.10 180 286 7.5E-29 T 29-03-2018 CVS48_RS26320 9d3608a1a0b178413aa3be45a8d69801 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 68 424 1.7E-80 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS26320 9d3608a1a0b178413aa3be45a8d69801 525 SUPERFAMILY SSF53850 21 524 3.26E-124 T 29-03-2018 CVS48_RS26320 9d3608a1a0b178413aa3be45a8d69801 525 PIRSF PIRSF002741 15 523 1.0E-82 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS26320 9d3608a1a0b178413aa3be45a8d69801 525 Gene3D G3DSA:3.90.76.10 35 178 9.3E-33 T 29-03-2018 CVS48_RS27790 3ba6050e00f5dff60242072120e122c1 185 SUPERFAMILY SSF88946 28 114 3.3E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS27790 3ba6050e00f5dff60242072120e122c1 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 177 2.7E-21 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS27790 3ba6050e00f5dff60242072120e122c1 185 SUPERFAMILY SSF88659 105 182 1.83E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS27790 3ba6050e00f5dff60242072120e122c1 185 Gene3D G3DSA:1.10.1740.10 14 94 4.4E-15 T 29-03-2018 CVS48_RS27790 3ba6050e00f5dff60242072120e122c1 185 Pfam PF04542 Sigma-70 region 2 31 94 6.6E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS27790 3ba6050e00f5dff60242072120e122c1 185 Gene3D G3DSA:1.10.10.10 106 183 3.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27790 3ba6050e00f5dff60242072120e122c1 185 Pfam PF08281 Sigma-70, region 4 128 179 4.2E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS18010 820691018b14356f0be0a79fcbe60090 264 Gene3D G3DSA:3.40.190.10 153 263 9.7E-14 T 29-03-2018 CVS48_RS18010 820691018b14356f0be0a79fcbe60090 264 SUPERFAMILY SSF53850 2 261 4.08E-66 T 29-03-2018 CVS48_RS18010 820691018b14356f0be0a79fcbe60090 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 259 3.2E-63 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS18010 820691018b14356f0be0a79fcbe60090 264 SMART SM00062 39 261 2.9E-64 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS18010 820691018b14356f0be0a79fcbe60090 264 SMART SM00079 37 260 0.0022 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CVS48_RS18010 820691018b14356f0be0a79fcbe60090 264 Gene3D G3DSA:3.40.190.10 1 152 1.0E-35 T 29-03-2018 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 Pfam PF00696 Amino acid kinase family 3 229 1.4E-48 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 412 2.0E-122 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 9.7E-6 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 PRINTS PR00474 Glutamate 5-kinase family signature 33 47 9.7E-6 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 SUPERFAMILY SSF55021 257 335 4.12E-16 T 29-03-2018 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 SUPERFAMILY SSF55021 340 414 3.15E-22 T 29-03-2018 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 Gene3D G3DSA:3.30.70.260 247 337 2.5E-21 T 29-03-2018 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 Gene3D G3DSA:3.40.1160.10 1 246 1.7E-73 T 29-03-2018 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 Pfam PF01842 ACT domain 278 333 2.3E-8 T 29-03-2018 IPR002912 ACT domain CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 Pfam PF13840 ACT domain 346 409 1.3E-12 T 29-03-2018 IPR027795 GATS-like ACT domain CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 SUPERFAMILY SSF53633 4 250 6.41E-73 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 412 1.7E-108 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 PIRSF PIRSF000726 59 420 8.0E-132 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 PIRSF PIRSF000726 1 62 1.2E-20 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CVS48_RS24035 de5a6c44337585c3353c703b065b9ca6 421 Gene3D G3DSA:3.30.70.260 338 412 2.1E-19 T 29-03-2018 CVS48_RS13175 97b5a48b622977ab88662f4d6129a26c 211 Pfam PF13417 Glutathione S-transferase, N-terminal domain 14 85 1.5E-11 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS13175 97b5a48b622977ab88662f4d6129a26c 211 Gene3D G3DSA:1.20.1050.10 100 207 2.0E-8 T 29-03-2018 CVS48_RS13175 97b5a48b622977ab88662f4d6129a26c 211 Gene3D G3DSA:3.40.30.10 2 99 8.9E-22 T 29-03-2018 CVS48_RS13175 97b5a48b622977ab88662f4d6129a26c 211 SUPERFAMILY SSF47616 90 204 2.9E-7 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS13175 97b5a48b622977ab88662f4d6129a26c 211 Pfam PF14834 Glutathione S-transferase, C-terminal domain 95 204 1.6E-35 T 29-03-2018 IPR034338 Glutathione S-transferases, subfamily 4, C-terminal KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 CVS48_RS13175 97b5a48b622977ab88662f4d6129a26c 211 SUPERFAMILY SSF52833 11 92 1.35E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS22710 81ac4b1fcd81785bb93811e8067f07a0 145 Gene3D G3DSA:3.10.490.10 1 143 1.9E-22 T 29-03-2018 CVS48_RS22710 81ac4b1fcd81785bb93811e8067f07a0 145 SUPERFAMILY SSF110857 2 137 1.26E-20 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CVS48_RS22710 81ac4b1fcd81785bb93811e8067f07a0 145 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 132 6.1E-16 T 29-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CVS48_RS28455 49e0e6896aecc6fa0ef2e4642422158d 212 SUPERFAMILY SSF54862 8 135 5.02E-28 T 29-03-2018 CVS48_RS28455 49e0e6896aecc6fa0ef2e4642422158d 212 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 116 127 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS28455 49e0e6896aecc6fa0ef2e4642422158d 212 Pfam PF14697 4Fe-4S dicluster domain 79 133 8.0E-18 T 29-03-2018 CVS48_RS28455 49e0e6896aecc6fa0ef2e4642422158d 212 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 5 143 6.0E-65 T 29-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 CVS48_RS28455 49e0e6896aecc6fa0ef2e4642422158d 212 Gene3D G3DSA:3.30.70.20 5 90 3.0E-9 T 29-03-2018 CVS48_RS28455 49e0e6896aecc6fa0ef2e4642422158d 212 Pfam PF04060 Putative Fe-S cluster 14 46 2.3E-15 T 29-03-2018 IPR007202 4Fe-4S domain GO:0051536 CVS48_RS28455 49e0e6896aecc6fa0ef2e4642422158d 212 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS28455 49e0e6896aecc6fa0ef2e4642422158d 212 Gene3D G3DSA:3.30.70.20 122 165 2.1E-5 T 29-03-2018 CVS48_RS28455 49e0e6896aecc6fa0ef2e4642422158d 212 Gene3D G3DSA:3.30.70.20 91 121 6.6E-13 T 29-03-2018 CVS48_RS21405 8eae62bbc40e43b742a438c47aaa4e36 155 SMART SM00347 34 134 7.1E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS21405 8eae62bbc40e43b742a438c47aaa4e36 155 Gene3D G3DSA:1.10.10.10 6 153 3.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21405 8eae62bbc40e43b742a438c47aaa4e36 155 SUPERFAMILY SSF46785 15 148 8.47E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21405 8eae62bbc40e43b742a438c47aaa4e36 155 Pfam PF13463 Winged helix DNA-binding domain 41 107 1.0E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS21405 8eae62bbc40e43b742a438c47aaa4e36 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS21405 8eae62bbc40e43b742a438c47aaa4e36 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS21405 8eae62bbc40e43b742a438c47aaa4e36 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS21405 8eae62bbc40e43b742a438c47aaa4e36 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20355 9c32118cb32d8c54796a9d6551edca5a 341 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS20355 9c32118cb32d8c54796a9d6551edca5a 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 226 312 1.0E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS20355 9c32118cb32d8c54796a9d6551edca5a 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 293 1.7E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS20355 9c32118cb32d8c54796a9d6551edca5a 341 Pfam PF00005 ABC transporter 31 177 1.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS20355 9c32118cb32d8c54796a9d6551edca5a 341 SMART SM00382 39 226 2.0E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS20355 9c32118cb32d8c54796a9d6551edca5a 341 Gene3D G3DSA:3.40.50.300 1 325 5.3E-77 T 29-03-2018 CVS48_RS20355 9c32118cb32d8c54796a9d6551edca5a 341 SUPERFAMILY SSF52540 6 248 1.85E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05150 3b7f9e7cc7a6ed71ef01490d1d325e77 189 Gene3D G3DSA:1.10.287.1060 23 107 8.0E-5 T 29-03-2018 CVS48_RS05150 3b7f9e7cc7a6ed71ef01490d1d325e77 189 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 177 17.552 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CVS48_RS05150 3b7f9e7cc7a6ed71ef01490d1d325e77 189 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 72 1.4E-20 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CVS48_RS05150 3b7f9e7cc7a6ed71ef01490d1d325e77 189 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 2.5E-16 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CVS48_RS05150 3b7f9e7cc7a6ed71ef01490d1d325e77 189 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 2.5E-16 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CVS48_RS05150 3b7f9e7cc7a6ed71ef01490d1d325e77 189 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 2.5E-16 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CVS48_RS05150 3b7f9e7cc7a6ed71ef01490d1d325e77 189 Pfam PF02416 mttA/Hcf106 family 4 51 1.6E-8 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CVS48_RS22580 166182b947e6ef57a12e97469f77d9f5 158 SUPERFAMILY SSF46785 6 142 6.76E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22580 166182b947e6ef57a12e97469f77d9f5 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 5.3E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS22580 166182b947e6ef57a12e97469f77d9f5 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 5.3E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS22580 166182b947e6ef57a12e97469f77d9f5 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 5.3E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS22580 166182b947e6ef57a12e97469f77d9f5 158 SMART SM00347 27 127 9.2E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS22580 166182b947e6ef57a12e97469f77d9f5 158 Gene3D G3DSA:1.10.10.10 3 148 2.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22580 166182b947e6ef57a12e97469f77d9f5 158 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CVS48_RS22580 166182b947e6ef57a12e97469f77d9f5 158 Pfam PF01047 MarR family 35 90 3.0E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS22580 166182b947e6ef57a12e97469f77d9f5 158 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 9 134 3.9E-48 T 29-03-2018 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 CVS48_RS04020 52b9445fb0ed787f9e4810892077f4c2 327 Gene3D G3DSA:3.40.50.300 2 326 7.1E-78 T 29-03-2018 CVS48_RS04020 52b9445fb0ed787f9e4810892077f4c2 327 SUPERFAMILY SSF52540 5 254 1.16E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04020 52b9445fb0ed787f9e4810892077f4c2 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 6.3E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS04020 52b9445fb0ed787f9e4810892077f4c2 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 317 7.6E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS04020 52b9445fb0ed787f9e4810892077f4c2 327 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS04020 52b9445fb0ed787f9e4810892077f4c2 327 SMART SM00382 34 233 7.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS04020 52b9445fb0ed787f9e4810892077f4c2 327 Pfam PF00005 ABC transporter 26 183 8.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 35 48 3.5E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 139 155 3.5E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 188 205 3.5E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 72 91 3.5E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 158 176 3.5E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 239 253 3.5E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 20 700 3.2E-271 T 29-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 Pfam PF00771 FHIPEP family 28 691 1.0E-270 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 144 167 - T 29-03-2018 IPR025505 FHIPEP conserved site CVS48_RS16835 956814f5a12c26ee6a61d8cbfa14b5e4 706 PIRSF PIRSF005419 4 706 1.1E-245 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CVS48_RS10220 a677e22540007515962f959f95f5de8a 336 Gene3D G3DSA:1.10.3470.10 3 296 2.1E-20 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS10220 a677e22540007515962f959f95f5de8a 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 290 1.3E-20 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS06850 65349e2493a461113794254eb576bf7d 200 SUPERFAMILY SSF48498 79 187 7.63E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS06850 65349e2493a461113794254eb576bf7d 200 Gene3D G3DSA:1.10.10.60 2 55 1.5E-14 T 29-03-2018 CVS48_RS06850 65349e2493a461113794254eb576bf7d 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 5.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS06850 65349e2493a461113794254eb576bf7d 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 5.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS06850 65349e2493a461113794254eb576bf7d 200 Gene3D G3DSA:1.10.357.10 56 188 1.5E-18 T 29-03-2018 CVS48_RS06850 65349e2493a461113794254eb576bf7d 200 SUPERFAMILY SSF46689 5 75 1.95E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS06850 65349e2493a461113794254eb576bf7d 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS22940 f9cd7f44653ef8130b69a65dbdfeeec0 120 PIRSF PIRSF037511 1 120 3.3E-33 T 29-03-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 CVS48_RS22940 f9cd7f44653ef8130b69a65dbdfeeec0 120 Pfam PF01253 Translation initiation factor SUI1 46 112 1.0E-14 T 29-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 CVS48_RS22940 f9cd7f44653ef8130b69a65dbdfeeec0 120 SUPERFAMILY SSF55159 7 116 2.75E-24 T 29-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 CVS48_RS22940 f9cd7f44653ef8130b69a65dbdfeeec0 120 Gene3D G3DSA:3.30.780.10 31 118 1.9E-13 T 29-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 CVS48_RS28250 add4e9e2652224848227cf9be5697478 302 SUPERFAMILY SSF46785 2 112 2.88E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28250 add4e9e2652224848227cf9be5697478 302 Gene3D G3DSA:3.40.190.10 89 179 2.1E-20 T 29-03-2018 CVS48_RS28250 add4e9e2652224848227cf9be5697478 302 Pfam PF03466 LysR substrate binding domain 90 292 7.9E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS28250 add4e9e2652224848227cf9be5697478 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.1E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS28250 add4e9e2652224848227cf9be5697478 302 SUPERFAMILY SSF53850 92 297 2.5E-37 T 29-03-2018 CVS48_RS28250 add4e9e2652224848227cf9be5697478 302 Gene3D G3DSA:1.10.10.10 1 85 3.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28250 add4e9e2652224848227cf9be5697478 302 Gene3D G3DSA:3.40.190.10 180 266 1.1E-18 T 29-03-2018 CVS48_RS23080 4e9f94bef494890ac8f2ffc9819c0ad8 255 Gene3D G3DSA:1.10.10.60 140 208 1.1E-11 T 29-03-2018 CVS48_RS23080 4e9f94bef494890ac8f2ffc9819c0ad8 255 Gene3D G3DSA:1.10.10.60 209 255 4.9E-9 T 29-03-2018 CVS48_RS23080 4e9f94bef494890ac8f2ffc9819c0ad8 255 Pfam PF12833 Helix-turn-helix domain 176 253 1.2E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS23080 4e9f94bef494890ac8f2ffc9819c0ad8 255 SUPERFAMILY SSF51182 12 186 3.41E-17 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS23080 4e9f94bef494890ac8f2ffc9819c0ad8 255 SMART SM00342 170 252 6.7E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS23080 4e9f94bef494890ac8f2ffc9819c0ad8 255 Pfam PF02311 AraC-like ligand binding domain 23 120 1.5E-5 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS23080 4e9f94bef494890ac8f2ffc9819c0ad8 255 SUPERFAMILY SSF46689 211 253 6.45E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS23080 4e9f94bef494890ac8f2ffc9819c0ad8 255 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 205 248 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS23080 4e9f94bef494890ac8f2ffc9819c0ad8 255 Gene3D G3DSA:2.60.120.10 2 100 6.7E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS15150 81751c06d8756675319b4762d5c50311 412 Gene3D G3DSA:1.10.3430.10 1 391 6.4E-128 T 29-03-2018 CVS48_RS15150 81751c06d8756675319b4762d5c50311 412 PRINTS PR00342 Rhesus blood group protein signature 236 258 2.2E-7 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CVS48_RS15150 81751c06d8756675319b4762d5c50311 412 PRINTS PR00342 Rhesus blood group protein signature 205 223 2.2E-7 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CVS48_RS15150 81751c06d8756675319b4762d5c50311 412 PRINTS PR00342 Rhesus blood group protein signature 105 121 2.2E-7 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CVS48_RS15150 81751c06d8756675319b4762d5c50311 412 PRINTS PR00342 Rhesus blood group protein signature 291 309 2.2E-7 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CVS48_RS15150 81751c06d8756675319b4762d5c50311 412 SUPERFAMILY SSF111352 2 391 7.45E-126 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CVS48_RS15150 81751c06d8756675319b4762d5c50311 412 ProSitePatterns PS01219 Ammonium transporters signature. 166 191 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CVS48_RS15150 81751c06d8756675319b4762d5c50311 412 Pfam PF00909 Ammonium Transporter Family 8 410 2.0E-121 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CVS48_RS15150 81751c06d8756675319b4762d5c50311 412 TIGRFAM TIGR00836 amt: ammonium transporter 5 410 5.7E-135 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CVS48_RS22555 e81d6aee8ac91f8dc68a2121b39fabfa 318 SUPERFAMILY SSF52283 6 136 4.91E-32 T 29-03-2018 CVS48_RS22555 e81d6aee8ac91f8dc68a2121b39fabfa 318 Gene3D G3DSA:3.40.50.720 5 117 8.2E-28 T 29-03-2018 CVS48_RS22555 e81d6aee8ac91f8dc68a2121b39fabfa 318 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 152 179 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CVS48_RS22555 e81d6aee8ac91f8dc68a2121b39fabfa 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 317 8.1E-26 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CVS48_RS22555 e81d6aee8ac91f8dc68a2121b39fabfa 318 SUPERFAMILY SSF51735 104 287 3.78E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS22555 e81d6aee8ac91f8dc68a2121b39fabfa 318 Gene3D G3DSA:3.40.50.720 118 289 7.1E-50 T 29-03-2018 CVS48_RS22555 e81d6aee8ac91f8dc68a2121b39fabfa 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 286 1.4E-48 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS04800 519f0e3ad89e693009ccae258b1ba05c 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 1.7E-8 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS04800 519f0e3ad89e693009ccae258b1ba05c 247 Gene3D G3DSA:3.40.50.300 5 244 4.4E-55 T 29-03-2018 CVS48_RS04800 519f0e3ad89e693009ccae258b1ba05c 247 Pfam PF00005 ABC transporter 24 177 1.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS04800 519f0e3ad89e693009ccae258b1ba05c 247 SUPERFAMILY SSF52540 7 245 1.57E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04800 519f0e3ad89e693009ccae258b1ba05c 247 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 7 247 2.7E-113 T 29-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD CVS48_RS06525 e378eefcde3fe6be07af17230f5af6dd 173 Pfam PF00333 Ribosomal protein S5, N-terminal domain 18 81 3.5E-24 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CVS48_RS06525 e378eefcde3fe6be07af17230f5af6dd 173 ProSitePatterns PS00585 Ribosomal protein S5 signature. 35 67 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CVS48_RS06525 e378eefcde3fe6be07af17230f5af6dd 173 Gene3D G3DSA:3.30.160.20 17 78 5.6E-22 T 29-03-2018 CVS48_RS06525 e378eefcde3fe6be07af17230f5af6dd 173 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 17 170 4.2E-63 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CVS48_RS06525 e378eefcde3fe6be07af17230f5af6dd 173 Pfam PF03719 Ribosomal protein S5, C-terminal domain 94 164 3.1E-27 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CVS48_RS06525 e378eefcde3fe6be07af17230f5af6dd 173 Gene3D G3DSA:3.30.230.10 83 173 1.4E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS06525 e378eefcde3fe6be07af17230f5af6dd 173 SUPERFAMILY SSF54768 15 82 9.42E-21 T 29-03-2018 CVS48_RS06525 e378eefcde3fe6be07af17230f5af6dd 173 SUPERFAMILY SSF54211 86 166 1.04E-24 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS06525 e378eefcde3fe6be07af17230f5af6dd 173 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 170 33.761 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CVS48_RS10430 c130a0e844a0e8d79679ac29fb907fec 272 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS10430 c130a0e844a0e8d79679ac29fb907fec 272 Gene3D G3DSA:3.40.50.300 4 265 2.0E-59 T 29-03-2018 CVS48_RS10430 c130a0e844a0e8d79679ac29fb907fec 272 SMART SM00382 31 229 3.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS10430 c130a0e844a0e8d79679ac29fb907fec 272 SUPERFAMILY SSF52540 6 250 1.55E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10430 c130a0e844a0e8d79679ac29fb907fec 272 Pfam PF00005 ABC transporter 22 181 1.9E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 1.6E-78 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 Gene3D G3DSA:3.30.1490.20 124 210 2.5E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 SUPERFAMILY SSF51246 331 443 3.09E-43 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 6.5E-38 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 Gene3D G3DSA:3.30.470.20 211 444 4.3E-94 T 29-03-2018 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 SUPERFAMILY SSF56059 83 347 7.6E-70 T 29-03-2018 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 Gene3D G3DSA:3.40.50.20 1 123 2.4E-53 T 29-03-2018 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.7E-45 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 SUPERFAMILY SSF52440 1 113 2.73E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 4.0E-221 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CVS48_RS03180 40375eca6d5a42b0c88c68a1d774b55a 448 SMART SM00878 336 441 1.7E-63 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS06725 cd7a2b9bf107af0704ae0e3f9f7919f1 1208 SUPERFAMILY SSF52540 134 305 3.67E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06725 cd7a2b9bf107af0704ae0e3f9f7919f1 1208 Gene3D G3DSA:3.40.50.300 81 303 6.6E-8 T 29-03-2018 CVS48_RS06725 cd7a2b9bf107af0704ae0e3f9f7919f1 1208 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 15 1206 0.0 T 29-03-2018 IPR017731 Type VI secretion system, IcmF CVS48_RS06725 cd7a2b9bf107af0704ae0e3f9f7919f1 1208 Pfam PF06761 Intracellular multiplication and human macrophage-killing 524 832 2.2E-83 T 29-03-2018 IPR009612 ImcF-related CVS48_RS06725 cd7a2b9bf107af0704ae0e3f9f7919f1 1208 Pfam PF06744 Type VI secretion protein IcmF C-terminal 958 1156 3.1E-58 T 29-03-2018 IPR010623 Type VI secretion system IcmF, C-terminal CVS48_RS06725 cd7a2b9bf107af0704ae0e3f9f7919f1 1208 Pfam PF14331 ImcF-related N-terminal domain 209 471 6.2E-95 T 29-03-2018 IPR025743 ImcF-related, N-terminal domain CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 Gene3D G3DSA:1.10.287.950 213 316 1.3E-17 T 29-03-2018 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 Gene3D G3DSA:1.10.287.950 317 512 7.6E-48 T 29-03-2018 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 SMART SM00304 208 260 2.9E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 SMART SM01049 33 125 3.9E-20 T 29-03-2018 IPR033480 Single Cache domain 2 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 Gene3D G3DSA:3.30.450.20 27 184 8.7E-38 T 29-03-2018 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 Pfam PF17200 Single Cache domain 2 38 185 1.0E-33 T 29-03-2018 IPR033480 Single Cache domain 2 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 Pfam PF00672 HAMP domain 210 257 2.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 SUPERFAMILY SSF58104 228 509 6.54E-71 T 29-03-2018 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 320 476 7.1E-48 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 SMART SM00283 261 508 6.0E-86 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 359 386 2.4E-52 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 68 83 2.4E-52 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 282 311 2.4E-52 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 388 417 2.4E-52 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS00340 53096684cf93d3e5028f96ec76473767 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 436 465 2.4E-52 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS18005 1e33ada66cc819238a645624c853a90e 273 Pfam PF08534 Redoxin 147 258 6.0E-16 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CVS48_RS18005 1e33ada66cc819238a645624c853a90e 273 Gene3D G3DSA:3.40.30.10 130 273 2.4E-25 T 29-03-2018 CVS48_RS18005 1e33ada66cc819238a645624c853a90e 273 SUPERFAMILY SSF52833 109 268 1.47E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS18005 1e33ada66cc819238a645624c853a90e 273 ProSitePatterns PS00194 Thioredoxin family active site. 164 182 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 Gene3D G3DSA:3.40.50.720 9 297 3.6E-107 T 29-03-2018 CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 36 203 2.7E-31 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 235 453 4.0E-74 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 PRINTS PR00084 Mannitol dehydrogenase signature 234 247 1.1E-14 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 PRINTS PR00084 Mannitol dehydrogenase signature 37 47 1.1E-14 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 PRINTS PR00084 Mannitol dehydrogenase signature 264 279 1.1E-14 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 PRINTS PR00084 Mannitol dehydrogenase signature 195 208 1.1E-14 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 Gene3D G3DSA:1.10.1040.10 299 515 8.7E-65 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 SUPERFAMILY SSF51735 12 297 5.12E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS03630 20abb2567942dc47c0011e8a3bb0934e 515 SUPERFAMILY SSF48179 301 512 6.12E-57 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 SUPERFAMILY SSF48557 11 447 2.04E-114 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 Gene3D G3DSA:1.10.275.10 4 106 4.8E-24 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 16 444 3.5E-110 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 3.4E-25 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 3.4E-25 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 3.4E-25 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 3.4E-25 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 443 1.2E-15 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 Gene3D G3DSA:1.10.40.30 365 443 1.3E-18 T 29-03-2018 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 Gene3D G3DSA:1.20.200.10 107 364 6.4E-77 T 29-03-2018 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 1.0E-10 T 29-03-2018 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 1.0E-10 T 29-03-2018 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 1.0E-10 T 29-03-2018 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 1.0E-10 T 29-03-2018 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 SMART SM00998 365 444 2.1E-22 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 Pfam PF00206 Lyase 17 298 1.4E-53 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CVS48_RS11635 fc9fc79bbb3121f80140d4ae287ba7fe 454 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CVS48_RS14615 73eba8f0cb935996e42d5a5154e7bd41 89 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 21 45 - T 29-03-2018 IPR001455 TusA-like domain CVS48_RS14615 73eba8f0cb935996e42d5a5154e7bd41 89 Pfam PF01206 Sulfurtransferase TusA 19 84 9.5E-22 T 29-03-2018 IPR001455 TusA-like domain CVS48_RS14615 73eba8f0cb935996e42d5a5154e7bd41 89 SUPERFAMILY SSF64307 3 88 1.05E-22 T 29-03-2018 IPR001455 TusA-like domain CVS48_RS14615 73eba8f0cb935996e42d5a5154e7bd41 89 Gene3D G3DSA:3.30.110.40 1 89 1.4E-25 T 29-03-2018 IPR001455 TusA-like domain CVS48_RS12185 96fc73d86e8360360bc974505f5dd7a7 293 Pfam PF01145 SPFH domain / Band 7 family 36 209 5.2E-30 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS12185 96fc73d86e8360360bc974505f5dd7a7 293 SUPERFAMILY SSF117892 64 200 3.14E-13 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS12185 96fc73d86e8360360bc974505f5dd7a7 293 SMART SM00244 32 195 4.8E-4 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 Gene3D G3DSA:3.40.50.720 1 204 1.6E-57 T 29-03-2018 CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 SUPERFAMILY SSF51735 9 239 3.04E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 Pfam PF00106 short chain dehydrogenase 11 202 3.9E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 184 9.4E-4 T 29-03-2018 CVS48_RS19555 56cd81919e38b2eef210039aa0fc34c5 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 Pfam PF02803 Thiolase, C-terminal domain 288 424 4.4E-41 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 Pfam PF00108 Thiolase, N-terminal domain 6 280 1.5E-55 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 424 9.2E-125 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 SUPERFAMILY SSF53901 6 287 3.51E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 SUPERFAMILY SSF53901 289 424 1.42E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 Gene3D G3DSA:3.40.47.10 2 290 4.6E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 ProSitePatterns PS00737 Thiolases signature 2. 372 388 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 PIRSF PIRSF000429 1 427 4.3E-129 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 Gene3D G3DSA:3.40.47.10 291 423 2.7E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23845 1f9f0c38390b1c74cbc1c85384104089 431 ProSitePatterns PS00099 Thiolases active site. 407 420 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CVS48_RS04115 cf4006087a82c17e662058977fa39787 80 Gene3D G3DSA:1.20.20.10 3 75 1.1E-14 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CVS48_RS04115 cf4006087a82c17e662058977fa39787 80 PRINTS PR00124 ATP synthase C subunit signature 10 29 8.9E-5 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04115 cf4006087a82c17e662058977fa39787 80 PRINTS PR00124 ATP synthase C subunit signature 31 46 8.9E-5 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04115 cf4006087a82c17e662058977fa39787 80 PRINTS PR00124 ATP synthase C subunit signature 48 73 8.9E-5 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04115 cf4006087a82c17e662058977fa39787 80 SUPERFAMILY SSF81333 4 77 4.71E-18 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CVS48_RS04115 cf4006087a82c17e662058977fa39787 80 Pfam PF00137 ATP synthase subunit C 9 71 2.9E-10 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CVS48_RS04115 cf4006087a82c17e662058977fa39787 80 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 75 7.9E-22 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CVS48_RS04115 cf4006087a82c17e662058977fa39787 80 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04115 cf4006087a82c17e662058977fa39787 80 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 73 14.112 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS16875 5fd2bbd069b8b26408e37fa40c59913e 489 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 410 488 6.7E-20 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CVS48_RS16875 5fd2bbd069b8b26408e37fa40c59913e 489 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 184 471 4.2E-48 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CVS48_RS16875 5fd2bbd069b8b26408e37fa40c59913e 489 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 2 227 9.4E-37 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CVS48_RS16875 5fd2bbd069b8b26408e37fa40c59913e 489 Pfam PF07559 Flagellar basal body protein FlaE 249 370 5.8E-17 T 29-03-2018 IPR011491 Flagellar hook protein FlgE CVS48_RS16875 5fd2bbd069b8b26408e37fa40c59913e 489 SUPERFAMILY SSF117143 244 450 1.23E-63 T 29-03-2018 CVS48_RS16875 5fd2bbd069b8b26408e37fa40c59913e 489 SUPERFAMILY SSF117143 73 164 1.23E-63 T 29-03-2018 CVS48_RS16875 5fd2bbd069b8b26408e37fa40c59913e 489 Gene3D G3DSA:2.60.98.20 141 371 6.1E-22 T 29-03-2018 IPR011491 Flagellar hook protein FlgE CVS48_RS16875 5fd2bbd069b8b26408e37fa40c59913e 489 Pfam PF00460 Flagella basal body rod protein 6 33 2.5E-10 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CVS48_RS00390 0c6bb3496c7f5d85f462ae84b9602159 199 Gene3D G3DSA:3.40.630.30 1 195 1.0E-24 T 29-03-2018 CVS48_RS00390 0c6bb3496c7f5d85f462ae84b9602159 199 SUPERFAMILY SSF55729 6 174 2.92E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS00390 0c6bb3496c7f5d85f462ae84b9602159 199 Pfam PF13302 Acetyltransferase (GNAT) domain 11 151 5.8E-30 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS13025 0fa6227112bd2bd43f7211d5178389de 212 Gene3D G3DSA:3.40.50.2020 1 206 4.3E-59 T 29-03-2018 CVS48_RS13025 0fa6227112bd2bd43f7211d5178389de 212 SUPERFAMILY SSF53271 3 206 1.57E-65 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CVS48_RS13025 0fa6227112bd2bd43f7211d5178389de 212 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 42.462 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CVS48_RS13025 0fa6227112bd2bd43f7211d5178389de 212 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 1.2E-62 T 29-03-2018 CVS48_RS13025 0fa6227112bd2bd43f7211d5178389de 212 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 207 3.8E-83 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CVS48_RS14235 f97d85a524e28c259831b3acf1496ac1 210 SUPERFAMILY SSF53098 38 201 2.04E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS14235 f97d85a524e28c259831b3acf1496ac1 210 SMART SM00479 38 204 2.0E-30 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CVS48_RS14235 f97d85a524e28c259831b3acf1496ac1 210 Pfam PF00929 Exonuclease 40 194 1.0E-20 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CVS48_RS14235 f97d85a524e28c259831b3acf1496ac1 210 Gene3D G3DSA:3.30.420.10 20 202 7.9E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 Pfam PF01336 OB-fold nucleic acid binding domain 67 141 3.7E-16 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 Gene3D G3DSA:3.30.930.10 154 503 2.5E-98 T 29-03-2018 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 388 404 1.3E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 260 277 1.3E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 242 255 1.3E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 213 229 1.3E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 197 207 1.3E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 Pfam PF00152 tRNA synthetases class II (D, K and N) 160 503 4.4E-82 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 Gene3D G3DSA:2.40.50.140 14 153 7.9E-39 T 29-03-2018 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 SUPERFAMILY SSF50249 12 153 8.06E-43 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 SUPERFAMILY SSF55681 160 504 6.51E-115 T 29-03-2018 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 15 505 2.2E-192 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CVS48_RS21820 c188e9f8d2d0a3c306ec8ad20d5fafdb 507 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 20 506 43.491 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CVS48_RS12165 9256dff38856118d921254567f825dee 268 Pfam PF12833 Helix-turn-helix domain 181 255 6.6E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS12165 9256dff38856118d921254567f825dee 268 SUPERFAMILY SSF51182 30 181 1.49E-14 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS12165 9256dff38856118d921254567f825dee 268 Gene3D G3DSA:2.60.120.10 16 105 7.4E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS12165 9256dff38856118d921254567f825dee 268 Gene3D G3DSA:1.10.10.60 153 213 1.6E-8 T 29-03-2018 CVS48_RS12165 9256dff38856118d921254567f825dee 268 SUPERFAMILY SSF46689 212 255 1.29E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS12165 9256dff38856118d921254567f825dee 268 SMART SM00342 173 255 2.2E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS12165 9256dff38856118d921254567f825dee 268 Gene3D G3DSA:1.10.10.60 214 265 4.1E-8 T 29-03-2018 CVS48_RS06820 339ca14aaa5aa4b565a8e635e53a29fe 388 Gene3D G3DSA:3.30.390.10 1 115 2.3E-67 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS06820 339ca14aaa5aa4b565a8e635e53a29fe 388 SMART SM00922 162 259 8.0E-13 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CVS48_RS06820 339ca14aaa5aa4b565a8e635e53a29fe 388 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 134 8.5E-5 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CVS48_RS06820 339ca14aaa5aa4b565a8e635e53a29fe 388 SUPERFAMILY SSF54826 1 138 5.07E-30 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS06820 339ca14aaa5aa4b565a8e635e53a29fe 388 Gene3D G3DSA:3.20.20.120 116 371 2.0E-47 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS06820 339ca14aaa5aa4b565a8e635e53a29fe 388 SUPERFAMILY SSF51604 123 380 1.46E-53 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS06820 339ca14aaa5aa4b565a8e635e53a29fe 388 Pfam PF13378 Enolase C-terminal domain-like 165 376 8.0E-41 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS18720 78c906215fbc5c9ea027aa71dcf3c455 207 SUPERFAMILY SSF47240 82 197 1.99E-5 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS18720 78c906215fbc5c9ea027aa71dcf3c455 207 Pfam PF13628 Domain of unknown function (DUF4142) 62 197 8.5E-47 T 29-03-2018 IPR025419 Domain of unknown function DUF4142 CVS48_RS18720 78c906215fbc5c9ea027aa71dcf3c455 207 Gene3D G3DSA:1.20.1260.10 50 201 2.4E-28 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS26250 1b8f0ce9f4988a7d7f976b5a5871d5fc 375 Pfam PF00005 ABC transporter 34 175 4.5E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS26250 1b8f0ce9f4988a7d7f976b5a5871d5fc 375 SUPERFAMILY SSF52540 18 257 5.94E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26250 1b8f0ce9f4988a7d7f976b5a5871d5fc 375 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS26250 1b8f0ce9f4988a7d7f976b5a5871d5fc 375 Pfam PF08402 TOBE domain 293 373 8.2E-13 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS26250 1b8f0ce9f4988a7d7f976b5a5871d5fc 375 SUPERFAMILY SSF50331 251 372 9.07E-14 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS26250 1b8f0ce9f4988a7d7f976b5a5871d5fc 375 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 48 373 4.4E-123 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CVS48_RS26250 1b8f0ce9f4988a7d7f976b5a5871d5fc 375 SMART SM00382 42 227 1.1E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS26250 1b8f0ce9f4988a7d7f976b5a5871d5fc 375 Gene3D G3DSA:2.40.50.140 296 357 0.0015 T 29-03-2018 CVS48_RS26250 1b8f0ce9f4988a7d7f976b5a5871d5fc 375 Gene3D G3DSA:3.40.50.300 14 253 6.3E-72 T 29-03-2018 CVS48_RS09095 7e2ef0f6bb7ccc72482d7e5f0233bf82 187 SUPERFAMILY SSF52507 2 179 3.66E-61 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CVS48_RS09095 7e2ef0f6bb7ccc72482d7e5f0233bf82 187 Gene3D G3DSA:3.40.50.1950 2 182 7.0E-51 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CVS48_RS09095 7e2ef0f6bb7ccc72482d7e5f0233bf82 187 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 178 1.9E-70 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CVS48_RS09095 7e2ef0f6bb7ccc72482d7e5f0233bf82 187 Pfam PF02441 Flavoprotein 3 165 2.7E-26 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CVS48_RS09095 7e2ef0f6bb7ccc72482d7e5f0233bf82 187 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 185 36.743 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CVS48_RS19210 445dd32816365ebd91fc3388876af236 353 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 71 85 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CVS48_RS19210 445dd32816365ebd91fc3388876af236 353 SMART SM00829 8 350 0.006 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS19210 445dd32816365ebd91fc3388876af236 353 Gene3D G3DSA:3.90.180.10 1 171 1.3E-36 T 29-03-2018 CVS48_RS19210 445dd32816365ebd91fc3388876af236 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 140 2.8E-28 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS19210 445dd32816365ebd91fc3388876af236 353 SUPERFAMILY SSF51735 147 319 2.55E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19210 445dd32816365ebd91fc3388876af236 353 Gene3D G3DSA:3.40.50.720 172 321 5.7E-22 T 29-03-2018 CVS48_RS19210 445dd32816365ebd91fc3388876af236 353 Pfam PF00107 Zinc-binding dehydrogenase 187 314 7.5E-24 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS19210 445dd32816365ebd91fc3388876af236 353 SUPERFAMILY SSF50129 1 171 4.72E-37 T 29-03-2018 IPR011032 GroES-like CVS48_RS10465 f49b3b7770bebd543a739bac8820917a 403 Gene3D G3DSA:3.40.50.720 241 365 2.2E-16 T 29-03-2018 CVS48_RS10465 f49b3b7770bebd543a739bac8820917a 403 Pfam PF07885 Ion channel 155 226 3.5E-15 T 29-03-2018 IPR013099 Potassium channel domain CVS48_RS10465 f49b3b7770bebd543a739bac8820917a 403 Pfam PF02254 TrkA-N domain 251 365 1.9E-15 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CVS48_RS10465 f49b3b7770bebd543a739bac8820917a 403 SUPERFAMILY SSF51735 248 381 1.18E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS10465 f49b3b7770bebd543a739bac8820917a 403 SUPERFAMILY SSF81324 129 260 8.63E-21 T 29-03-2018 CVS48_RS10465 f49b3b7770bebd543a739bac8820917a 403 Gene3D G3DSA:1.10.287.70 131 229 7.2E-16 T 29-03-2018 CVS48_RS03295 dbb52f7d49ea9f5437a9513bf93a9fd6 224 Pfam PF03737 Aldolase/RraA 30 176 2.3E-44 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS03295 dbb52f7d49ea9f5437a9513bf93a9fd6 224 SUPERFAMILY SSF89562 29 185 7.85E-44 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS03295 dbb52f7d49ea9f5437a9513bf93a9fd6 224 Gene3D G3DSA:3.50.30.40 23 197 2.7E-51 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS14220 7a28fcc762a5a2a0a1704a4476b3e6a1 236 Gene3D G3DSA:3.40.30.10 1 101 1.4E-18 T 29-03-2018 CVS48_RS14220 7a28fcc762a5a2a0a1704a4476b3e6a1 236 Gene3D G3DSA:1.20.1050.10 102 206 2.2E-23 T 29-03-2018 CVS48_RS14220 7a28fcc762a5a2a0a1704a4476b3e6a1 236 Pfam PF14497 Glutathione S-transferase, C-terminal domain 110 216 1.2E-25 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS14220 7a28fcc762a5a2a0a1704a4476b3e6a1 236 SUPERFAMILY SSF52833 1 84 1.89E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS14220 7a28fcc762a5a2a0a1704a4476b3e6a1 236 SUPERFAMILY SSF47616 84 221 4.68E-21 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS27235 97ef6ac9449e65e8f45de1ffa81f405d 158 SUPERFAMILY SSF54534 13 157 2.55E-28 T 29-03-2018 CVS48_RS27235 97ef6ac9449e65e8f45de1ffa81f405d 158 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 13 86 2.0E-9 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CVS48_RS27235 97ef6ac9449e65e8f45de1ffa81f405d 158 Gene3D G3DSA:3.10.50.40 4 158 1.6E-14 T 29-03-2018 CVS48_RS01720 0d8e85ae2bc6a76a6b150000361d4cb0 218 Pfam PF04752 ChaC-like protein 42 208 2.0E-41 T 29-03-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 Reactome: R-HSA-174403 CVS48_RS01720 0d8e85ae2bc6a76a6b150000361d4cb0 218 Gene3D G3DSA:3.10.490.10 26 213 1.0E-32 T 29-03-2018 CVS48_RS01720 0d8e85ae2bc6a76a6b150000361d4cb0 218 SUPERFAMILY SSF110857 42 157 2.75E-11 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CVS48_RS26650 a692ebf3805ce729bb84e5625600e938 499 Gene3D G3DSA:3.30.465.10 109 253 1.9E-39 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS26650 a692ebf3805ce729bb84e5625600e938 499 Gene3D G3DSA:1.10.45.10 432 471 5.4E-10 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CVS48_RS26650 a692ebf3805ce729bb84e5625600e938 499 SUPERFAMILY SSF55103 205 474 3.6E-75 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS26650 a692ebf3805ce729bb84e5625600e938 499 Gene3D G3DSA:3.30.43.10 5 108 7.8E-23 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS26650 a692ebf3805ce729bb84e5625600e938 499 Pfam PF01565 FAD binding domain 56 195 1.8E-40 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS26650 a692ebf3805ce729bb84e5625600e938 499 SUPERFAMILY SSF56176 19 231 6.07E-69 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS26650 a692ebf3805ce729bb84e5625600e938 499 Pfam PF02913 FAD linked oxidases, C-terminal domain 231 471 4.0E-66 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS27350 b2389ce6c4e6845e31ce2d112a80de69 126 Pfam PF01245 Ribosomal protein L19 9 117 2.9E-45 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27350 b2389ce6c4e6845e31ce2d112a80de69 126 SUPERFAMILY SSF50104 2 118 4.81E-43 T 29-03-2018 IPR008991 Translation protein SH3-like domain CVS48_RS27350 b2389ce6c4e6845e31ce2d112a80de69 126 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 2.0E-46 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27350 b2389ce6c4e6845e31ce2d112a80de69 126 PIRSF PIRSF002191 1 126 2.1E-50 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27350 b2389ce6c4e6845e31ce2d112a80de69 126 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 29.697 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27350 b2389ce6c4e6845e31ce2d112a80de69 126 PRINTS PR00061 Ribosomal protein L19 signature 38 67 3.8E-32 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27350 b2389ce6c4e6845e31ce2d112a80de69 126 PRINTS PR00061 Ribosomal protein L19 signature 92 117 3.8E-32 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27350 b2389ce6c4e6845e31ce2d112a80de69 126 PRINTS PR00061 Ribosomal protein L19 signature 8 37 3.8E-32 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS27350 b2389ce6c4e6845e31ce2d112a80de69 126 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS21600 be3470af69b11d14b859b204efa45c14 705 Pfam PF00665 Integrase core domain 270 408 2.4E-7 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS21600 be3470af69b11d14b859b204efa45c14 705 Gene3D G3DSA:1.10.10.60 175 247 0.0017 T 29-03-2018 CVS48_RS21600 be3470af69b11d14b859b204efa45c14 705 Gene3D G3DSA:3.30.420.10 265 500 2.0E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS24335 dc647fd44ea8ee7a46660ba20890f669 1058 Gene3D G3DSA:2.60.40.10 676 864 3.8E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS24335 dc647fd44ea8ee7a46660ba20890f669 1058 Pfam PF13550 Putative phage tail protein 372 532 1.9E-24 T 29-03-2018 IPR032876 Tip attachment protein J CVS48_RS24335 dc647fd44ea8ee7a46660ba20890f669 1058 Pfam PF09327 Domain of unknown function (DUF1983) 906 982 1.7E-22 T 29-03-2018 IPR015406 Domain of unknown function DUF1983 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 24 523 8.6E-109 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 SUPERFAMILY SSF56235 10 531 3.67E-175 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 350 368 2.1E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 44 69 2.1E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 111 129 2.1E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 129 148 2.1E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 429 446 2.1E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 374 392 2.1E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 227 243 2.1E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 256 275 2.1E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 420 2.1E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24945 8756b49bd443f9db7683532d3aaec54d 531 Pfam PF01019 Gamma-glutamyltranspeptidase 37 526 9.1E-158 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS24430 49e52d73b8c59abeff9cc60799a8ddcf 662 Pfam PF05876 Phage terminase large subunit (GpA) 12 593 3.1E-150 T 29-03-2018 IPR008866 Bacteriophage lambda, GpA CVS48_RS10705 fa6333d7a322f06a9ed94782935f39c3 371 Gene3D G3DSA:3.40.50.2000 187 351 1.3E-36 T 29-03-2018 CVS48_RS10705 fa6333d7a322f06a9ed94782935f39c3 371 Pfam PF00534 Glycosyl transferases group 1 184 339 1.6E-33 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS10705 fa6333d7a322f06a9ed94782935f39c3 371 Gene3D G3DSA:3.40.50.2000 1 186 8.4E-25 T 29-03-2018 CVS48_RS10705 fa6333d7a322f06a9ed94782935f39c3 371 SUPERFAMILY SSF53756 2 365 7.99E-72 T 29-03-2018 CVS48_RS10705 fa6333d7a322f06a9ed94782935f39c3 371 Pfam PF13579 Glycosyl transferase 4-like domain 13 172 3.3E-13 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS10195 4de5bf40c94890239d0ebb60003b2351 322 Gene3D G3DSA:3.40.50.300 1 228 8.8E-59 T 29-03-2018 CVS48_RS10195 4de5bf40c94890239d0ebb60003b2351 322 Pfam PF00005 ABC transporter 20 163 7.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS10195 4de5bf40c94890239d0ebb60003b2351 322 SUPERFAMILY SSF52540 3 220 7.31E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10195 4de5bf40c94890239d0ebb60003b2351 322 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS10195 4de5bf40c94890239d0ebb60003b2351 322 SMART SM00382 29 209 3.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS02625 3b9d74cc9adf80b4b92a9d0185b560ee 301 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 19 32 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CVS48_RS02625 3b9d74cc9adf80b4b92a9d0185b560ee 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 16 176 1.2E-47 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CVS48_RS02625 3b9d74cc9adf80b4b92a9d0185b560ee 301 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 179 298 7.1E-34 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CVS48_RS02625 3b9d74cc9adf80b4b92a9d0185b560ee 301 Gene3D G3DSA:3.40.50.720 12 177 3.5E-36 T 29-03-2018 CVS48_RS02625 3b9d74cc9adf80b4b92a9d0185b560ee 301 SUPERFAMILY SSF51735 15 176 3.8E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS02625 3b9d74cc9adf80b4b92a9d0185b560ee 301 PIRSF PIRSF000103 10 301 9.9E-73 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CVS48_RS02625 3b9d74cc9adf80b4b92a9d0185b560ee 301 SUPERFAMILY SSF48179 178 300 5.21E-40 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS02625 3b9d74cc9adf80b4b92a9d0185b560ee 301 Gene3D G3DSA:1.10.1040.10 178 301 7.4E-34 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS03780 fd380d2977ac8e80f845021c6a74c3cf 151 Gene3D G3DSA:3.40.30.10 27 108 0.001 T 29-03-2018 CVS48_RS03780 fd380d2977ac8e80f845021c6a74c3cf 151 Pfam PF04214 Protein of unknown function, DUF 54 121 6.1E-29 T 29-03-2018 IPR007332 Protein of unknown function DUF411 CVS48_RS24925 7819f91946d654e2920110c6bc823307 290 PIRSF PIRSF000103 1 290 5.7E-74 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CVS48_RS24925 7819f91946d654e2920110c6bc823307 290 Gene3D G3DSA:1.10.1040.10 165 290 1.8E-20 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS24925 7819f91946d654e2920110c6bc823307 290 Gene3D G3DSA:3.40.50.720 1 164 1.0E-30 T 29-03-2018 CVS48_RS24925 7819f91946d654e2920110c6bc823307 290 SUPERFAMILY SSF51735 1 163 3.09E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS24925 7819f91946d654e2920110c6bc823307 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 163 3.3E-36 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CVS48_RS24925 7819f91946d654e2920110c6bc823307 290 SUPERFAMILY SSF48179 164 289 7.71E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS24925 7819f91946d654e2920110c6bc823307 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 281 2.3E-16 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 Pfam PF01479 S4 domain 124 167 1.0E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 Gene3D G3DSA:3.10.290.10 122 180 3.9E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 SMART SM00363 122 180 7.9E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 189 349 5.2E-50 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 Gene3D G3DSA:3.30.70.1560 267 335 3.8E-20 T 29-03-2018 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 SUPERFAMILY SSF55174 123 214 5.76E-18 T 29-03-2018 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 223 237 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 Pfam PF00849 RNA pseudouridylate synthase 185 318 1.6E-15 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 SUPERFAMILY SSF55120 184 348 9.44E-39 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS27175 80acf95e1fb88a442be97d4c4a5bf1f9 624 Gene3D G3DSA:3.30.70.580 181 266 1.2E-13 T 29-03-2018 CVS48_RS11230 91a6d4c82bba493e71f0ca347dae1107 385 Gene3D G3DSA:3.40.47.10 13 134 6.2E-5 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS11230 91a6d4c82bba493e71f0ca347dae1107 385 Pfam PF02803 Thiolase, C-terminal domain 264 361 7.4E-5 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS11230 91a6d4c82bba493e71f0ca347dae1107 385 SUPERFAMILY SSF53901 6 229 8.59E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS11230 91a6d4c82bba493e71f0ca347dae1107 385 PIRSF PIRSF000429 4 374 3.1E-28 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS11230 91a6d4c82bba493e71f0ca347dae1107 385 SUPERFAMILY SSF53901 261 375 7.04E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS11230 91a6d4c82bba493e71f0ca347dae1107 385 Gene3D G3DSA:3.40.47.10 147 377 1.4E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS21860 7de0c0458d64207c885d2faa6239968d 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 276 7.8E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS21860 7de0c0458d64207c885d2faa6239968d 292 Gene3D G3DSA:1.10.3470.10 3 283 2.3E-44 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 SUPERFAMILY SSF56645 5 242 1.44E-72 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 Gene3D G3DSA:2.40.110.10 120 216 5.6E-37 T 29-03-2018 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 PIRSF PIRSF016578 11 361 2.5E-19 T 29-03-2018 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 117 4.7E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 2.3E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 Gene3D G3DSA:1.20.140.10 217 382 1.3E-58 T 29-03-2018 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 Gene3D G3DSA:1.10.540.10 2 119 2.2E-29 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 SUPERFAMILY SSF47203 227 379 1.32E-55 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS03965 0438051cff5d9e53bdaa6850c41d9b5b 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 2.7E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 Gene3D G3DSA:3.30.70.240 402 483 2.6E-19 T 29-03-2018 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 Gene3D G3DSA:2.40.30.10 191 301 1.3E-19 T 29-03-2018 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 Pfam PF00009 Elongation factor Tu GTP binding domain 5 195 1.2E-54 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 PRINTS PR00315 GTP-binding elongation factor signature 123 132 8.2E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 PRINTS PR00315 GTP-binding elongation factor signature 7 20 8.2E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 PRINTS PR00315 GTP-binding elongation factor signature 87 98 8.2E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 PRINTS PR00315 GTP-binding elongation factor signature 71 81 8.2E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 PRINTS PR00315 GTP-binding elongation factor signature 51 59 8.2E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 Gene3D G3DSA:3.40.50.300 2 67 2.2E-10 T 29-03-2018 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 SUPERFAMILY SSF54980 303 388 9.35E-13 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 Pfam PF03144 Elongation factor Tu domain 2 219 290 1.2E-9 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 600 7.0E-286 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 Pfam PF00679 Elongation factor G C-terminus 397 478 1.5E-22 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 Gene3D G3DSA:3.40.50.300 68 190 9.2E-29 T 29-03-2018 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 SUPERFAMILY SSF54980 399 514 4.12E-28 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 Gene3D G3DSA:2.40.50.250 484 574 4.1E-40 T 29-03-2018 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 Gene3D G3DSA:3.30.70.870 303 401 1.5E-31 T 29-03-2018 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 SUPERFAMILY SSF52540 4 207 3.33E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 134 1.6E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS27145 b460d342218235b97d129d6f5f1bf9d2 607 SUPERFAMILY SSF50447 151 300 8.08E-29 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 SUPERFAMILY SSF51905 13 300 4.63E-88 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 SUPERFAMILY SSF51905 484 543 4.63E-88 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 SUPERFAMILY SSF54373 302 485 1.18E-45 T 29-03-2018 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 91 114 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 PIRSF PIRSF000137 1 544 3.3E-146 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 Pfam PF00732 GMC oxidoreductase 15 307 1.8E-86 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 Gene3D G3DSA:4.10.450.10 49 113 1.2E-26 T 29-03-2018 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 266 280 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 Gene3D G3DSA:3.40.50.720 3 48 0.0012 T 29-03-2018 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 Pfam PF05199 GMC oxidoreductase 399 537 5.7E-37 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS08940 dcd60ba17d8b62aa599776a3dfb28440 544 Gene3D G3DSA:3.30.560.10 114 500 1.1E-104 T 29-03-2018 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 PIRSF PIRSF000018 20 426 2.1E-138 T 29-03-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 314 400 4.9E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 Gene3D G3DSA:1.10.760.10 27 160 8.1E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 SUPERFAMILY SSF46626 191 305 1.3E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 Gene3D G3DSA:1.10.760.10 308 426 1.3E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 Pfam PF00034 Cytochrome c 201 297 3.1E-4 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 Pfam PF00034 Cytochrome c 45 145 8.2E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 Gene3D G3DSA:1.10.760.10 161 307 2.2E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 SUPERFAMILY SSF46626 318 421 1.39E-24 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS07730 4b07d38af2f3af6171969d38da59882e 426 SUPERFAMILY SSF46626 43 167 1.56E-25 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS15525 b6371621aede17657a1bfec9322ad3dc 306 Gene3D G3DSA:3.40.190.10 184 275 6.6E-4 T 29-03-2018 CVS48_RS15525 b6371621aede17657a1bfec9322ad3dc 306 SUPERFAMILY SSF46785 4 86 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15525 b6371621aede17657a1bfec9322ad3dc 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 1.0E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15525 b6371621aede17657a1bfec9322ad3dc 306 SUPERFAMILY SSF53850 82 305 4.52E-29 T 29-03-2018 CVS48_RS15525 b6371621aede17657a1bfec9322ad3dc 306 Gene3D G3DSA:1.10.10.10 2 90 3.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15525 b6371621aede17657a1bfec9322ad3dc 306 Gene3D G3DSA:3.40.190.10 91 183 8.8E-14 T 29-03-2018 CVS48_RS15525 b6371621aede17657a1bfec9322ad3dc 306 Pfam PF03466 LysR substrate binding domain 90 304 1.8E-27 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS15730 51488f5ef377cffbf333c4ccb5bee4a4 60 Pfam PF04995 Heme exporter protein D (CcmD) 11 39 2.0E-8 T 29-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 CVS48_RS15730 51488f5ef377cffbf333c4ccb5bee4a4 60 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 9 39 7.7E-7 T 29-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 CVS48_RS07710 143aa300ffff94a0c6e86c33ce148161 194 Gene3D G3DSA:3.30.160.70 18 86 9.8E-20 T 29-03-2018 CVS48_RS07710 143aa300ffff94a0c6e86c33ce148161 194 SUPERFAMILY SSF46767 91 172 3.14E-28 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS07710 143aa300ffff94a0c6e86c33ce148161 194 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 94 172 9.7E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS07710 143aa300ffff94a0c6e86c33ce148161 194 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 92 171 1.1E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS07710 143aa300ffff94a0c6e86c33ce148161 194 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 142 148 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS07710 143aa300ffff94a0c6e86c33ce148161 194 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 22 172 38.695 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CVS48_RS07710 143aa300ffff94a0c6e86c33ce148161 194 Gene3D G3DSA:1.10.10.10 87 174 1.2E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07710 143aa300ffff94a0c6e86c33ce148161 194 SUPERFAMILY SSF53155 19 97 5.1E-19 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CVS48_RS22175 4e990f4bb149d1d285152ebab5865132 273 SUPERFAMILY SSF51161 3 257 4.16E-76 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS22175 4e990f4bb149d1d285152ebab5865132 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 167 6.1E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS22175 4e990f4bb149d1d285152ebab5865132 273 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 272 1.8E-141 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 CVS48_RS22175 4e990f4bb149d1d285152ebab5865132 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 135 163 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CVS48_RS22175 4e990f4bb149d1d285152ebab5865132 273 Gene3D G3DSA:1.10.166.10 4 70 1.7E-29 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 CVS48_RS22175 4e990f4bb149d1d285152ebab5865132 273 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 4 70 6.4E-27 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 CVS48_RS22175 4e990f4bb149d1d285152ebab5865132 273 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 176 210 1.0E-12 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS22175 4e990f4bb149d1d285152ebab5865132 273 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 273 56.237 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 CVS48_RS22175 4e990f4bb149d1d285152ebab5865132 273 Gene3D G3DSA:2.160.10.10 88 258 4.7E-37 T 29-03-2018 CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 Gene3D G3DSA:3.30.360.10 123 231 3.7E-31 T 29-03-2018 CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 Gene3D G3DSA:3.40.50.720 1 118 4.8E-29 T 29-03-2018 CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 SUPERFAMILY SSF51735 1 123 1.1E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 SUPERFAMILY SSF51735 233 263 1.1E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 SUPERFAMILY SSF55347 124 233 3.71E-35 T 29-03-2018 CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 122 2.8E-38 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 262 34.174 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 125 261 1.0E-40 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 262 4.4E-89 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 PIRSF PIRSF000161 1 263 6.6E-85 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS00465 bcd610f1f63b517748a3e0cf5b3c6360 263 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 147 164 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS12320 ce4af9d56aa86bb3eac98abccf285489 514 Pfam PF13091 PLD-like domain 79 224 5.2E-14 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS12320 ce4af9d56aa86bb3eac98abccf285489 514 Pfam PF13091 PLD-like domain 318 458 2.9E-20 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS12320 ce4af9d56aa86bb3eac98abccf285489 514 Gene3D G3DSA:3.30.870.10 310 499 4.4E-22 T 29-03-2018 CVS48_RS12320 ce4af9d56aa86bb3eac98abccf285489 514 SUPERFAMILY SSF56024 41 240 5.49E-44 T 29-03-2018 CVS48_RS12320 ce4af9d56aa86bb3eac98abccf285489 514 Gene3D G3DSA:3.30.870.10 49 235 1.1E-28 T 29-03-2018 CVS48_RS12320 ce4af9d56aa86bb3eac98abccf285489 514 SUPERFAMILY SSF56024 280 460 2.47E-29 T 29-03-2018 CVS48_RS12320 ce4af9d56aa86bb3eac98abccf285489 514 SMART SM00155 405 432 6.1E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS12320 ce4af9d56aa86bb3eac98abccf285489 514 SMART SM00155 165 192 0.029 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS18115 7255aefa84f349d7c148ae39ac703618 800 Pfam PF07715 TonB-dependent Receptor Plug Domain 160 253 8.5E-15 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS18115 7255aefa84f349d7c148ae39ac703618 800 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 783 800 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS18115 7255aefa84f349d7c148ae39ac703618 800 Gene3D G3DSA:2.170.130.10 115 273 2.7E-21 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS18115 7255aefa84f349d7c148ae39ac703618 800 Gene3D G3DSA:2.40.170.20 274 800 2.2E-63 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS18115 7255aefa84f349d7c148ae39ac703618 800 SUPERFAMILY SSF56935 119 800 2.62E-102 T 29-03-2018 CVS48_RS18115 7255aefa84f349d7c148ae39ac703618 800 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 161 800 8.4E-106 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS18115 7255aefa84f349d7c148ae39ac703618 800 SMART SM00965 63 114 8.5E-11 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS18115 7255aefa84f349d7c148ae39ac703618 800 Pfam PF00593 TonB dependent receptor 475 797 1.5E-36 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS11925 d08526385d7d5408818370802693b0bd 322 PIRSF PIRSF017082 1 322 1.4E-75 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11925 d08526385d7d5408818370802693b0bd 322 Gene3D G3DSA:3.40.190.10 122 249 1.9E-13 T 29-03-2018 CVS48_RS11925 d08526385d7d5408818370802693b0bd 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 1.8E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11925 d08526385d7d5408818370802693b0bd 322 SUPERFAMILY SSF53850 109 284 2.68E-17 T 29-03-2018 CVS48_RS04685 bfb9a70e19a89bd63acb05f01a51bd71 281 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 2 219 3.2E-35 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CVS48_RS04685 bfb9a70e19a89bd63acb05f01a51bd71 281 PIRSF PIRSF015582 1 281 6.1E-67 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like CVS48_RS04685 bfb9a70e19a89bd63acb05f01a51bd71 281 Gene3D G3DSA:3.20.20.60 1 237 4.1E-45 T 29-03-2018 CVS48_RS04685 bfb9a70e19a89bd63acb05f01a51bd71 281 SUPERFAMILY SSF51621 1 229 2.3E-53 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 Pfam PF00005 ABC transporter 24 181 4.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 Pfam PF00005 ABC transporter 332 485 1.2E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 SUPERFAMILY SSF52540 3 253 9.63E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 Gene3D G3DSA:3.40.50.300 1 284 5.3E-70 T 29-03-2018 CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 Gene3D G3DSA:3.40.50.300 302 575 5.0E-75 T 29-03-2018 CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 ProSitePatterns PS00211 ABC transporters family signature. 457 471 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 SMART SM00382 32 231 2.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 SMART SM00382 340 534 2.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 SUPERFAMILY SSF52540 320 555 4.19E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 268 2.4E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS05345 803a063040ac0a9c1ccde45ba802fd12 576 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 536 568 1.1E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS11390 ee6b89a0aaa2dbe5e649f86436a3ddea 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 250 2.4E-45 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS11390 ee6b89a0aaa2dbe5e649f86436a3ddea 258 SUPERFAMILY SSF52096 1 251 8.56E-67 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS11390 ee6b89a0aaa2dbe5e649f86436a3ddea 258 Gene3D G3DSA:3.90.226.10 1 258 1.4E-65 T 29-03-2018 CVS48_RS27310 e8cbb0961c0878a3f2f5689f35d4daeb 329 SUPERFAMILY SSF47240 46 289 1.27E-83 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS27310 e8cbb0961c0878a3f2f5689f35d4daeb 329 Gene3D G3DSA:1.10.620.20 17 313 5.7E-82 T 29-03-2018 CVS48_RS27310 e8cbb0961c0878a3f2f5689f35d4daeb 329 Pfam PF05138 Phenylacetic acid catabolic protein 36 311 2.5E-105 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CVS48_RS27310 e8cbb0961c0878a3f2f5689f35d4daeb 329 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 26 315 1.2E-165 T 29-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 CVS48_RS06310 4a84f556fb6c69033a14d9c71184715a 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 3.1E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS06310 4a84f556fb6c69033a14d9c71184715a 238 Gene3D G3DSA:1.10.10.10 122 231 1.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06310 4a84f556fb6c69033a14d9c71184715a 238 Pfam PF00072 Response regulator receiver domain 6 113 2.8E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS06310 4a84f556fb6c69033a14d9c71184715a 238 SUPERFAMILY SSF52172 2 186 4.84E-35 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS06310 4a84f556fb6c69033a14d9c71184715a 238 SMART SM00862 148 224 1.8E-16 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS06310 4a84f556fb6c69033a14d9c71184715a 238 SMART SM00448 1 113 8.7E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS06310 4a84f556fb6c69033a14d9c71184715a 238 Gene3D G3DSA:3.40.50.2300 1 121 1.7E-32 T 29-03-2018 CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 SUPERFAMILY SSF46894 18 92 3.68E-6 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 Gene3D G3DSA:1.25.40.10 128 249 9.4E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 SUPERFAMILY SSF48452 1122 1193 9.87E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 SUPERFAMILY SSF55073 282 409 6.12E-7 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 Gene3D G3DSA:1.25.40.10 924 1216 3.6E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 Gene3D G3DSA:3.30.70.1230 271 435 3.8E-6 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 Gene3D G3DSA:3.40.50.300 436 645 1.7E-8 T 29-03-2018 CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 SUPERFAMILY SSF52540 570 685 4.2E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 SUPERFAMILY SSF52540 431 497 4.2E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 Pfam PF03704 Bacterial transcriptional activator domain 146 249 2.3E-14 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 Gene3D G3DSA:1.10.10.10 10 109 4.1E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 SMART SM01043 111 250 2.2E-15 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 SUPERFAMILY SSF48452 145 250 7.59E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS08575 59e97afaaf2dedd65e94318c3370fb47 1217 Pfam PF13191 AAA ATPase domain 433 625 5.1E-17 T 29-03-2018 CVS48_RS21705 36408c70302fe9b85715ce77099983d8 146 SUPERFAMILY SSF54427 11 145 7.58E-16 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS21705 36408c70302fe9b85715ce77099983d8 146 Pfam PF12680 SnoaL-like domain 22 121 5.3E-10 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CVS48_RS21705 36408c70302fe9b85715ce77099983d8 146 Gene3D G3DSA:3.10.450.50 1 146 2.7E-15 T 29-03-2018 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 SUPERFAMILY SSF56712 3 613 5.1E-166 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 SMART SM00437 278 560 1.2E-76 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 Gene3D G3DSA:1.10.460.10 158 356 4.1E-37 T 29-03-2018 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 Gene3D G3DSA:2.70.20.10 371 481 2.3E-25 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 SMART SM00493 3 125 1.4E-16 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 Pfam PF13342 C-terminal repeat of topoisomerase 754 814 6.2E-18 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 Pfam PF13342 C-terminal repeat of topoisomerase 650 708 4.7E-21 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 408 424 5.8E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 321 330 5.8E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 523 537 5.8E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 5.8E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 5.8E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 Pfam PF01751 Toprim domain 4 131 2.1E-12 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 Gene3D G3DSA:3.40.50.140 3 153 6.8E-33 T 29-03-2018 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 Pfam PF01131 DNA topoisomerase 155 598 1.9E-110 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 SMART SM00436 125 220 1.6E-22 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 Gene3D G3DSA:1.10.460.10 482 875 1.7E-28 T 29-03-2018 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 618 1.9E-166 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CVS48_RS05725 2669cb3284f687aea42215107eb97d85 875 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 315 330 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CVS48_RS19890 d9a2a81d7db2a5a792d8d345e2638c8c 163 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 61 98 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CVS48_RS19890 d9a2a81d7db2a5a792d8d345e2638c8c 163 Gene3D G3DSA:3.40.140.10 3 163 3.8E-52 T 29-03-2018 CVS48_RS19890 d9a2a81d7db2a5a792d8d345e2638c8c 163 SUPERFAMILY SSF53927 8 157 1.34E-55 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CVS48_RS19890 d9a2a81d7db2a5a792d8d345e2638c8c 163 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 15 157 47.636 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CVS48_RS19890 d9a2a81d7db2a5a792d8d345e2638c8c 163 Pfam PF14437 MafB19-like deaminase 11 157 1.1E-29 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 SUPERFAMILY SSF46785 14 125 1.56E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 Gene3D G3DSA:1.10.10.10 10 97 1.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 74 2.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 2.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 2.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 2.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 Pfam PF03466 LysR substrate binding domain 101 314 1.6E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 Gene3D G3DSA:3.40.190.10 200 283 2.4E-15 T 29-03-2018 CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 SUPERFAMILY SSF53850 102 316 3.83E-38 T 29-03-2018 CVS48_RS11150 9d82624a55d5767a3aae14eef258c16f 318 Gene3D G3DSA:3.40.190.10 103 199 1.2E-24 T 29-03-2018 CVS48_RS12880 ba8f8b001e116b2f890f36bb126ecbe7 294 SUPERFAMILY SSF53474 55 289 1.43E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS12880 ba8f8b001e116b2f890f36bb126ecbe7 294 Gene3D G3DSA:3.40.50.1820 48 289 3.0E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS12880 ba8f8b001e116b2f890f36bb126ecbe7 294 Pfam PF01738 Dienelactone hydrolase family 65 289 1.6E-64 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CVS48_RS22415 41b177a2023cdf4dd9275a602a9e3f23 104 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 3 99 29.048 T 29-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CVS48_RS22415 41b177a2023cdf4dd9275a602a9e3f23 104 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 22 99 1.5E-35 T 29-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CVS48_RS22415 41b177a2023cdf4dd9275a602a9e3f23 104 Gene3D G3DSA:3.30.1390.10 11 103 2.1E-34 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CVS48_RS22415 41b177a2023cdf4dd9275a602a9e3f23 104 SUPERFAMILY SSF54736 21 103 4.5E-32 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CVS48_RS07860 520fbf85f32188bc866fd2b2088e6b40 413 SUPERFAMILY SSF53383 12 399 1.63E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS07860 520fbf85f32188bc866fd2b2088e6b40 413 Gene3D G3DSA:3.90.1150.10 281 402 4.0E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS07860 520fbf85f32188bc866fd2b2088e6b40 413 Pfam PF00155 Aminotransferase class I and II 61 391 8.1E-40 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS07860 520fbf85f32188bc866fd2b2088e6b40 413 Gene3D G3DSA:3.40.640.10 59 280 8.0E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS23410 76a6ecd28cfab87529e006cfe0d083f2 322 Gene3D G3DSA:3.40.190.10 121 232 5.5E-10 T 29-03-2018 CVS48_RS23410 76a6ecd28cfab87529e006cfe0d083f2 322 SUPERFAMILY SSF53850 109 284 7.24E-12 T 29-03-2018 CVS48_RS23410 76a6ecd28cfab87529e006cfe0d083f2 322 PIRSF PIRSF017082 1 321 3.3E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23410 76a6ecd28cfab87529e006cfe0d083f2 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 1.2E-89 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23720 1f101a2ef210960ca0c5eb0d78c82e02 315 Gene3D G3DSA:1.10.3130.10 68 189 2.6E-38 T 29-03-2018 CVS48_RS23720 1f101a2ef210960ca0c5eb0d78c82e02 315 PIRSF PIRSF000441 130 303 2.7E-51 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CVS48_RS23720 1f101a2ef210960ca0c5eb0d78c82e02 315 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 257 290 3.5E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS23720 1f101a2ef210960ca0c5eb0d78c82e02 315 Gene3D G3DSA:2.160.10.10 190 303 1.1E-26 T 29-03-2018 CVS48_RS23720 1f101a2ef210960ca0c5eb0d78c82e02 315 SUPERFAMILY SSF51161 115 299 8.18E-44 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 SUPERFAMILY SSF52490 15 207 2.88E-61 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 SMART SM00864 15 204 3.1E-101 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 SUPERFAMILY SSF55307 206 321 7.55E-40 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 172 1.4E-34 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 PRINTS PR00423 Cell division protein FtsZ signature 97 117 9.3E-46 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 PRINTS PR00423 Cell division protein FtsZ signature 211 232 9.3E-46 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 PRINTS PR00423 Cell division protein FtsZ signature 125 146 9.3E-46 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 PRINTS PR00423 Cell division protein FtsZ signature 188 210 9.3E-46 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 Gene3D G3DSA:3.40.50.1440 11 213 2.0E-38 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 SMART SM00865 206 324 2.7E-53 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 Gene3D G3DSA:3.30.1330.20 214 323 2.8E-43 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 324 1.9E-115 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 11 379 34.541 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CVS48_RS02445 7757419ef6e37858c4c588b676d4c3c2 394 Pfam PF12327 FtsZ family, C-terminal domain 221 315 5.2E-32 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CVS48_RS06075 dae598855dea18887966302e94ba5e22 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 310 2.7E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS06075 dae598855dea18887966302e94ba5e22 336 Pfam PF00005 ABC transporter 37 194 7.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS06075 dae598855dea18887966302e94ba5e22 336 SUPERFAMILY SSF52540 45 311 9.61E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06075 dae598855dea18887966302e94ba5e22 336 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS06075 dae598855dea18887966302e94ba5e22 336 Gene3D G3DSA:3.40.50.300 14 334 3.2E-70 T 29-03-2018 CVS48_RS06075 dae598855dea18887966302e94ba5e22 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 244 328 1.9E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS06075 dae598855dea18887966302e94ba5e22 336 SMART SM00382 45 244 1.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19505 e0366ea90649275c774a035170a40459 386 PIRSF PIRSF016578 3 194 1.2E-8 T 29-03-2018 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 PIRSF PIRSF016578 236 383 1.7E-6 T 29-03-2018 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 115 1.9E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 218 9.3E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 Gene3D G3DSA:2.40.110.10 114 219 4.4E-29 T 29-03-2018 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 SUPERFAMILY SSF56645 5 243 6.41E-63 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 Gene3D G3DSA:1.10.540.10 1 113 1.3E-29 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 SUPERFAMILY SSF47203 229 384 2.42E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 364 5.2E-34 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 Gene3D G3DSA:1.20.140.10 220 386 5.6E-48 T 29-03-2018 CVS48_RS19505 e0366ea90649275c774a035170a40459 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS25900 071a40d8cdfc0ce6f7348c734050601b 387 SUPERFAMILY SSF89796 2 386 7.85E-119 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS25900 071a40d8cdfc0ce6f7348c734050601b 387 Gene3D G3DSA:3.40.50.10540 1 386 3.4E-119 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS25900 071a40d8cdfc0ce6f7348c734050601b 387 Pfam PF02515 CoA-transferase family III 7 363 8.1E-101 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS27850 c0fcab9e9d5a4308b943015930983b3a 501 Pfam PF00860 Permease family 26 175 1.2E-33 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS27850 c0fcab9e9d5a4308b943015930983b3a 501 Pfam PF00860 Permease family 205 445 6.9E-66 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS27850 c0fcab9e9d5a4308b943015930983b3a 501 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 21 479 8.8E-112 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 SUPERFAMILY SSF58104 234 520 3.14E-74 T 29-03-2018 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 Pfam PF02203 Tar ligand binding domain homologue 1 165 1.9E-23 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 SMART SM00304 214 266 4.4E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 Gene3D G3DSA:1.10.287.1060 233 324 0.057 T 29-03-2018 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 Pfam PF00672 HAMP domain 214 262 4.5E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 482 2.5E-54 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 Gene3D G3DSA:1.20.120.30 24 188 3.0E-19 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 SMART SM00283 267 514 1.7E-90 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 SUPERFAMILY SSF47170 32 174 6.54E-19 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 Gene3D G3DSA:1.10.287.950 325 518 2.0E-48 T 29-03-2018 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 2.8E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 61 76 2.8E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 392 2.8E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 471 2.8E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 423 2.8E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS02295 6af3d6d0f2a93ac052dd5e4cee48c423 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 2.8E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS26510 889da15e05f9ded527461a173e59ae67 438 Gene3D G3DSA:1.20.120.450 15 160 1.5E-10 T 29-03-2018 CVS48_RS26510 889da15e05f9ded527461a173e59ae67 438 Pfam PF12867 DinB superfamily 26 160 3.2E-14 T 29-03-2018 IPR024775 DinB-like domain CVS48_RS26510 889da15e05f9ded527461a173e59ae67 438 SUPERFAMILY SSF56436 189 438 9.89E-67 T 29-03-2018 IPR016187 C-type lectin fold CVS48_RS26510 889da15e05f9ded527461a173e59ae67 438 Gene3D G3DSA:3.90.1580.10 179 438 6.8E-51 T 29-03-2018 CVS48_RS26510 889da15e05f9ded527461a173e59ae67 438 Pfam PF03781 Sulfatase-modifying factor enzyme 1 195 436 5.8E-31 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CVS48_RS26510 889da15e05f9ded527461a173e59ae67 438 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 24 435 2.8E-166 T 29-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 CVS48_RS28760 126610fdc962dbe24b6e609e986cee2a 222 ProSitePatterns PS00261 Glycoprotein hormones beta chain signature 1. 177 183 - T 29-03-2018 IPR018245 Gonadotropin, beta subunit, conserved site GO:0005179|GO:0005576 CVS48_RS28760 126610fdc962dbe24b6e609e986cee2a 222 SUPERFAMILY SSF46785 19 196 3.71E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28760 126610fdc962dbe24b6e609e986cee2a 222 Gene3D G3DSA:1.10.10.10 12 85 8.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26810 f5992955479da1cb304e6a28445d610a 232 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 185 1.0E-66 T 29-03-2018 IPR022301 Integral membrane protein YjbE CVS48_RS26810 f5992955479da1cb304e6a28445d610a 232 Pfam PF03741 Integral membrane protein TerC family 14 183 4.0E-43 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CVS48_RS28040 080debefdb87c0e986fbaa46333c2114 306 SUPERFAMILY SSF161098 93 289 6.8E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28040 080debefdb87c0e986fbaa46333c2114 306 Gene3D G3DSA:1.10.3720.10 3 293 2.5E-49 T 29-03-2018 CVS48_RS28040 080debefdb87c0e986fbaa46333c2114 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 3.0E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28645 58b90ca28a1c0c01c99e9fd8c7589ba9 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 333 352 1.2E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28645 58b90ca28a1c0c01c99e9fd8c7589ba9 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 385 411 1.2E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28645 58b90ca28a1c0c01c99e9fd8c7589ba9 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 1.2E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28645 58b90ca28a1c0c01c99e9fd8c7589ba9 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 1.2E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28645 58b90ca28a1c0c01c99e9fd8c7589ba9 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 245 269 1.2E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28645 58b90ca28a1c0c01c99e9fd8c7589ba9 500 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 71 132 2.3E-5 T 29-03-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28645 58b90ca28a1c0c01c99e9fd8c7589ba9 500 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 14 495 2.7E-183 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28645 58b90ca28a1c0c01c99e9fd8c7589ba9 500 Pfam PF00361 Proton-conducting membrane transporter 141 425 9.1E-78 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28615 417e381b2363ffebd3e331f3c776d29e 227 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 105 112 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CVS48_RS28615 417e381b2363ffebd3e331f3c776d29e 227 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 227 40.98 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CVS48_RS28615 417e381b2363ffebd3e331f3c776d29e 227 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 225 3.4E-59 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CVS48_RS28615 417e381b2363ffebd3e331f3c776d29e 227 Gene3D G3DSA:3.90.550.10 1 227 4.8E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS28615 417e381b2363ffebd3e331f3c776d29e 227 SUPERFAMILY SSF53448 5 227 2.12E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS28615 417e381b2363ffebd3e331f3c776d29e 227 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 225 1.3E-54 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CVS48_RS22640 478cc3b0011aa40d7fb33b1193541f70 130 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 14 122 5.9E-24 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CVS48_RS22640 478cc3b0011aa40d7fb33b1193541f70 130 TIGRFAM TIGR00494 crcB: protein CrcB 13 123 1.4E-24 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CVS48_RS22640 478cc3b0011aa40d7fb33b1193541f70 130 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 12 127 18.364 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CVS48_RS23995 451d91dd672744f40ef77904f0a4a35c 257 Pfam PF02146 Sir2 family 27 207 1.3E-50 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 CVS48_RS23995 451d91dd672744f40ef77904f0a4a35c 257 Gene3D G3DSA:3.40.50.1220 4 60 9.1E-11 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS23995 451d91dd672744f40ef77904f0a4a35c 257 Gene3D G3DSA:3.40.50.1220 61 255 8.8E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS23995 451d91dd672744f40ef77904f0a4a35c 257 SUPERFAMILY SSF52467 9 254 6.11E-80 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS23995 451d91dd672744f40ef77904f0a4a35c 257 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 20 257 58.394 T 29-03-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 CVS48_RS27735 ea759d9df85f381495e49a20d62acda1 210 SUPERFAMILY SSF49478 133 183 2.59E-6 T 29-03-2018 CVS48_RS27735 ea759d9df85f381495e49a20d62acda1 210 Gene3D G3DSA:2.60.40.1120 128 210 1.2E-5 T 29-03-2018 CVS48_RS27735 ea759d9df85f381495e49a20d62acda1 210 Pfam PF10670 Domain of unknown function (DUF4198) 74 183 5.3E-12 T 29-03-2018 IPR019613 Protein of unknown function DUF4198 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 Gene3D G3DSA:1.10.540.10 1 125 1.3E-42 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 PIRSF PIRSF016578 140 392 2.3E-12 T 29-03-2018 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 PIRSF PIRSF016578 13 101 0.01 T 29-03-2018 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 Gene3D G3DSA:1.20.140.10 223 392 9.3E-52 T 29-03-2018 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 387 7.5E-39 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 6.1E-28 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 SUPERFAMILY SSF47203 233 390 7.41E-44 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 SUPERFAMILY SSF56645 6 247 1.3E-88 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 123 3.3E-39 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS05505 386c05934db52dfa21216585fd6a8a23 392 Gene3D G3DSA:2.40.110.10 126 222 1.1E-41 T 29-03-2018 CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 Gene3D G3DSA:3.40.50.720 1 46 2.2E-10 T 29-03-2018 CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 Gene3D G3DSA:3.40.50.720 47 248 1.1E-56 T 29-03-2018 CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.8E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.8E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.8E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.8E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.8E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.8E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 3.0E-58 T 29-03-2018 CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 2.0E-4 T 29-03-2018 CVS48_RS02240 25b2f37d74d751b1b53f0254316459bf 248 SUPERFAMILY SSF51735 1 247 3.24E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS22040 c56c3008b860372b3a933c2e283709c2 132 SUPERFAMILY SSF55298 2 131 2.2E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS22040 c56c3008b860372b3a933c2e283709c2 132 Gene3D G3DSA:3.30.1330.40 1 131 3.1E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS22040 c56c3008b860372b3a933c2e283709c2 132 Pfam PF01042 Endoribonuclease L-PSP 18 130 4.4E-17 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS28410 fa3ccdd9c243393ceb93c6dce1d05359 437 SUPERFAMILY SSF103473 9 431 4.19E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS28410 fa3ccdd9c243393ceb93c6dce1d05359 437 Pfam PF00083 Sugar (and other) transporter 12 427 3.0E-36 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS28410 fa3ccdd9c243393ceb93c6dce1d05359 437 Gene3D G3DSA:1.20.1250.20 3 227 1.1E-22 T 29-03-2018 CVS48_RS28410 fa3ccdd9c243393ceb93c6dce1d05359 437 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS28410 fa3ccdd9c243393ceb93c6dce1d05359 437 Gene3D G3DSA:1.20.1250.20 243 436 2.1E-21 T 29-03-2018 CVS48_RS28410 fa3ccdd9c243393ceb93c6dce1d05359 437 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 318 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS29035 e73e129ae266919469ff47443d553985 325 SUPERFAMILY SSF50129 1 138 6.7E-38 T 29-03-2018 IPR011032 GroES-like CVS48_RS29035 e73e129ae266919469ff47443d553985 325 Gene3D G3DSA:3.40.50.720 133 309 7.4E-42 T 29-03-2018 CVS48_RS29035 e73e129ae266919469ff47443d553985 325 Gene3D G3DSA:3.90.180.10 1 132 3.1E-36 T 29-03-2018 CVS48_RS29035 e73e129ae266919469ff47443d553985 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 2.6E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS29035 e73e129ae266919469ff47443d553985 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 2.3E-144 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CVS48_RS29035 e73e129ae266919469ff47443d553985 325 SUPERFAMILY SSF51735 111 287 8.0E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS29035 e73e129ae266919469ff47443d553985 325 Pfam PF00107 Zinc-binding dehydrogenase 151 275 1.7E-30 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS29035 e73e129ae266919469ff47443d553985 325 SMART SM00829 10 323 5.8E-52 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS20190 0d248baee2bb9a4935c1b1dfe2415ba5 269 SMART SM00346 21 112 2.6E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS20190 0d248baee2bb9a4935c1b1dfe2415ba5 269 Pfam PF09339 IclR helix-turn-helix domain 23 74 1.3E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS20190 0d248baee2bb9a4935c1b1dfe2415ba5 269 SUPERFAMILY SSF55781 87 265 4.71E-41 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS20190 0d248baee2bb9a4935c1b1dfe2415ba5 269 SUPERFAMILY SSF46785 22 95 1.09E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20190 0d248baee2bb9a4935c1b1dfe2415ba5 269 Pfam PF01614 Bacterial transcriptional regulator 144 263 1.2E-19 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS20190 0d248baee2bb9a4935c1b1dfe2415ba5 269 Gene3D G3DSA:3.30.450.40 88 267 9.4E-43 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS20190 0d248baee2bb9a4935c1b1dfe2415ba5 269 Gene3D G3DSA:1.10.10.10 2 83 5.1E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19170 6b16d4fe934ee35e6536f13bd2740d26 411 SUPERFAMILY SSF51395 30 220 1.04E-91 T 29-03-2018 CVS48_RS19170 6b16d4fe934ee35e6536f13bd2740d26 411 SUPERFAMILY SSF51395 252 403 1.04E-91 T 29-03-2018 CVS48_RS19170 6b16d4fe934ee35e6536f13bd2740d26 411 Pfam PF01070 FMN-dependent dehydrogenase 40 404 3.0E-125 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CVS48_RS19170 6b16d4fe934ee35e6536f13bd2740d26 411 PIRSF PIRSF000138 12 407 3.1E-129 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CVS48_RS19170 6b16d4fe934ee35e6536f13bd2740d26 411 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 302 308 - T 29-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CVS48_RS19170 6b16d4fe934ee35e6536f13bd2740d26 411 Gene3D G3DSA:3.20.20.70 29 407 3.9E-93 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS10460 3d35843fccdfb01dcb9694404a43d143 522 Pfam PF00563 EAL domain 268 501 1.9E-66 T 29-03-2018 IPR001633 EAL domain CVS48_RS10460 3d35843fccdfb01dcb9694404a43d143 522 SUPERFAMILY SSF141868 268 514 2.09E-79 T 29-03-2018 IPR001633 EAL domain CVS48_RS10460 3d35843fccdfb01dcb9694404a43d143 522 Pfam PF12792 CSS motif domain associated with EAL 39 238 2.6E-30 T 29-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain CVS48_RS10460 3d35843fccdfb01dcb9694404a43d143 522 Gene3D G3DSA:3.20.20.450 261 516 7.0E-84 T 29-03-2018 IPR001633 EAL domain CVS48_RS10460 3d35843fccdfb01dcb9694404a43d143 522 SMART SM00052 262 506 1.2E-99 T 29-03-2018 IPR001633 EAL domain CVS48_RS03865 b35624817fb071fbe45912e904241ba4 302 Pfam PF12146 Serine aminopeptidase, S33 37 264 1.2E-57 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CVS48_RS03865 b35624817fb071fbe45912e904241ba4 302 Gene3D G3DSA:3.40.50.1820 2 286 1.4E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03865 b35624817fb071fbe45912e904241ba4 302 SUPERFAMILY SSF53474 8 282 2.73E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82693 41 134 6.28E-26 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 Gene3D G3DSA:3.30.70.1430 40 142 1.1E-25 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82693 277 333 1.15E-26 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82693 139 184 1.15E-26 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82693 818 867 5.49E-26 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82693 682 731 5.49E-26 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1039 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 Pfam PF00873 AcrB/AcrD/AcrF family 3 1036 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82693 575 681 1.94E-26 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82866 299 499 3.66E-53 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 Gene3D G3DSA:3.30.70.1430 589 678 5.9E-18 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82714 732 818 7.32E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 Gene3D G3DSA:1.20.1640.10 519 588 0.13 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 Gene3D G3DSA:1.20.1640.10 289 508 8.5E-53 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 Gene3D G3DSA:1.20.1640.10 856 1040 1.1E-39 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 Gene3D G3DSA:3.30.70.1440 682 776 1.5E-21 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 1.8E-92 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.8E-92 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.8E-92 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.8E-92 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.8E-92 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 1.8E-92 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.8E-92 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 1.8E-92 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.8E-92 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 Gene3D G3DSA:3.30.2090.10 183 278 6.0E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 Gene3D G3DSA:3.30.70.1320 777 855 1.0E-6 T 29-03-2018 CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82714 185 274 2.75E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CVS48_RS09440 136aabbde51bf3ba6af2845dceb9bd0f 1071 SUPERFAMILY SSF82866 841 1036 1.7E-46 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 SUPERFAMILY SSF51905 1 347 3.48E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 356 465 1.8E-38 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 337 8.4E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 Gene3D G3DSA:3.40.50.720 182 343 3.6E-32 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 352 373 1.2E-75 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 1.2E-75 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 185 210 1.2E-75 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 1.2E-75 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 1.2E-75 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 1.2E-75 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.2E-75 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 288 1.2E-75 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 1.2E-75 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PIRSF PIRSF000350 1 474 9.9E-82 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 Gene3D G3DSA:3.30.390.30 344 473 3.6E-43 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 474 2.5E-159 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 Gene3D G3DSA:3.50.50.60 1 181 8.3E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 5.0E-39 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 5.0E-39 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.0E-39 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 203 5.0E-39 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 5.0E-39 T 29-03-2018 CVS48_RS27800 f4aa3c2fc3d78b6cdc5fc676ba230570 475 SUPERFAMILY SSF55424 352 473 5.5E-42 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CVS48_RS22915 5c7e4f00072b242450c09830b4d70be5 610 Pfam PF00005 ABC transporter 409 544 1.0E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22915 5c7e4f00072b242450c09830b4d70be5 610 SMART SM00382 418 590 7.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22915 5c7e4f00072b242450c09830b4d70be5 610 SUPERFAMILY SSF90123 42 376 1.44E-20 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS22915 5c7e4f00072b242450c09830b4d70be5 610 SUPERFAMILY SSF52540 389 586 4.87E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22915 5c7e4f00072b242450c09830b4d70be5 610 Pfam PF06472 ABC transporter transmembrane region 2 37 325 9.3E-79 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CVS48_RS22915 5c7e4f00072b242450c09830b4d70be5 610 Gene3D G3DSA:3.40.50.300 378 583 1.0E-33 T 29-03-2018 CVS48_RS22915 5c7e4f00072b242450c09830b4d70be5 610 Gene3D G3DSA:1.20.1560.10 35 377 5.5E-37 T 29-03-2018 CVS48_RS00200 b28ff78a85ee2bb8e1ba568ca4180be9 263 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 144 164 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CVS48_RS00200 b28ff78a85ee2bb8e1ba568ca4180be9 263 Gene3D G3DSA:3.60.110.10 1 261 5.3E-63 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS00200 b28ff78a85ee2bb8e1ba568ca4180be9 263 SUPERFAMILY SSF56317 2 257 7.72E-66 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS00200 b28ff78a85ee2bb8e1ba568ca4180be9 263 Pfam PF00795 Carbon-nitrogen hydrolase 4 246 2.2E-38 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS09030 add523e3816dbe143238715d7666420c 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 5.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09030 add523e3816dbe143238715d7666420c 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 5.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09030 add523e3816dbe143238715d7666420c 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 5.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09030 add523e3816dbe143238715d7666420c 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS09030 add523e3816dbe143238715d7666420c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09030 add523e3816dbe143238715d7666420c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09030 add523e3816dbe143238715d7666420c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09030 add523e3816dbe143238715d7666420c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09030 add523e3816dbe143238715d7666420c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 2.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09030 add523e3816dbe143238715d7666420c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09030 add523e3816dbe143238715d7666420c 259 Gene3D G3DSA:3.40.50.720 49 259 2.4E-59 T 29-03-2018 CVS48_RS09030 add523e3816dbe143238715d7666420c 259 SUPERFAMILY SSF51735 9 258 3.73E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09030 add523e3816dbe143238715d7666420c 259 Gene3D G3DSA:3.40.50.10090 5 48 4.1E-10 T 29-03-2018 CVS48_RS09030 add523e3816dbe143238715d7666420c 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 256 1.9E-62 T 29-03-2018 CVS48_RS20630 679770f9f1e7a6bf461cc7abacf7b6b8 299 Gene3D G3DSA:1.10.10.10 1 91 1.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20630 679770f9f1e7a6bf461cc7abacf7b6b8 299 SUPERFAMILY SSF46785 1 81 1.71E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20630 679770f9f1e7a6bf461cc7abacf7b6b8 299 Gene3D G3DSA:3.40.190.10 92 181 9.0E-13 T 29-03-2018 CVS48_RS20630 679770f9f1e7a6bf461cc7abacf7b6b8 299 Pfam PF03466 LysR substrate binding domain 86 287 5.8E-23 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20630 679770f9f1e7a6bf461cc7abacf7b6b8 299 Gene3D G3DSA:3.40.190.10 182 262 1.3E-9 T 29-03-2018 CVS48_RS20630 679770f9f1e7a6bf461cc7abacf7b6b8 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20630 679770f9f1e7a6bf461cc7abacf7b6b8 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20630 679770f9f1e7a6bf461cc7abacf7b6b8 299 SUPERFAMILY SSF53850 86 295 2.53E-26 T 29-03-2018 CVS48_RS20630 679770f9f1e7a6bf461cc7abacf7b6b8 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.9E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23580 e7d06f5a168c4bea74338e423236a464 292 SUPERFAMILY SSF48452 65 229 6.33E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS23580 e7d06f5a168c4bea74338e423236a464 292 Gene3D G3DSA:1.25.40.10 159 253 1.1E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS23580 e7d06f5a168c4bea74338e423236a464 292 PIRSF PIRSF029658 9 279 4.4E-76 T 29-03-2018 IPR016931 Uncharacterised conserved protein UCP029658, TPR CVS48_RS23580 e7d06f5a168c4bea74338e423236a464 292 SMART SM00028 135 168 0.033 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS23580 e7d06f5a168c4bea74338e423236a464 292 SMART SM00028 169 202 82.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS23580 e7d06f5a168c4bea74338e423236a464 292 Gene3D G3DSA:1.25.40.10 52 158 2.8E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS08840 e5020e1eb766c271382618bb5f4b0bbd 365 Pfam PF10994 Protein of unknown function (DUF2817) 9 348 1.7E-115 T 29-03-2018 IPR021259 Protein of unknown function DUF2817 CVS48_RS08840 e5020e1eb766c271382618bb5f4b0bbd 365 Gene3D G3DSA:3.40.630.10 8 336 1.2E-17 T 29-03-2018 CVS48_RS08840 e5020e1eb766c271382618bb5f4b0bbd 365 SUPERFAMILY SSF53187 57 128 5.8E-14 T 29-03-2018 CVS48_RS08840 e5020e1eb766c271382618bb5f4b0bbd 365 SUPERFAMILY SSF53187 189 301 5.8E-14 T 29-03-2018 CVS48_RS27070 4fc3dca9f012d5eb64a6aab1a1691035 344 Gene3D G3DSA:3.40.50.300 1 243 1.9E-71 T 29-03-2018 CVS48_RS27070 4fc3dca9f012d5eb64a6aab1a1691035 344 SMART SM00382 20 203 4.9E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS27070 4fc3dca9f012d5eb64a6aab1a1691035 344 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS27070 4fc3dca9f012d5eb64a6aab1a1691035 344 SUPERFAMILY SSF50331 229 315 4.31E-5 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS27070 4fc3dca9f012d5eb64a6aab1a1691035 344 SUPERFAMILY SSF52540 2 235 1.9E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27070 4fc3dca9f012d5eb64a6aab1a1691035 344 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 2 344 2.5E-154 T 29-03-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 CVS48_RS27070 4fc3dca9f012d5eb64a6aab1a1691035 344 Pfam PF00005 ABC transporter 11 153 1.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS06985 700c1b04ee72947e7e47624cb9893e00 293 SUPERFAMILY SSF53448 1 289 2.12E-92 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS06985 700c1b04ee72947e7e47624cb9893e00 293 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 4 288 3.6E-156 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CVS48_RS06985 700c1b04ee72947e7e47624cb9893e00 293 Pfam PF00483 Nucleotidyl transferase 4 240 1.0E-68 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CVS48_RS06985 700c1b04ee72947e7e47624cb9893e00 293 Gene3D G3DSA:3.90.550.10 4 292 1.3E-72 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS10140 4ea4c51f42bbf99476b0e32b86a65ef1 394 SUPERFAMILY SSF54506 2 182 6.43E-70 T 29-03-2018 CVS48_RS10140 4ea4c51f42bbf99476b0e32b86a65ef1 394 Pfam PF04303 PrpF protein 6 390 8.2E-174 T 29-03-2018 IPR007400 PrpF protein CVS48_RS10140 4ea4c51f42bbf99476b0e32b86a65ef1 394 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 5 392 8.1E-226 T 29-03-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 CVS48_RS10140 4ea4c51f42bbf99476b0e32b86a65ef1 394 Gene3D G3DSA:3.10.310.10 200 372 1.2E-70 T 29-03-2018 CVS48_RS10140 4ea4c51f42bbf99476b0e32b86a65ef1 394 SUPERFAMILY SSF54506 188 392 1.73E-75 T 29-03-2018 CVS48_RS10140 4ea4c51f42bbf99476b0e32b86a65ef1 394 Gene3D G3DSA:3.10.310.10 5 199 1.1E-85 T 29-03-2018 CVS48_RS21000 3ba630550ccfd7d576964cae1b1d3ae8 140 Gene3D G3DSA:1.10.1220.10 17 59 2.2E-10 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CVS48_RS21000 3ba630550ccfd7d576964cae1b1d3ae8 140 SUPERFAMILY SSF47598 17 58 4.78E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CVS48_RS01755 eb3d29911184c63a57582a26828dc080 327 PIRSF PIRSF017082 1 327 8.3E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01755 eb3d29911184c63a57582a26828dc080 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 323 1.7E-91 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01755 eb3d29911184c63a57582a26828dc080 327 SUPERFAMILY SSF53850 117 287 6.15E-11 T 29-03-2018 CVS48_RS01755 eb3d29911184c63a57582a26828dc080 327 Gene3D G3DSA:3.40.190.10 36 298 9.0E-10 T 29-03-2018 CVS48_RS23955 c664410597ea0b93d6298c87399cd648 244 Gene3D G3DSA:3.40.1080.10 2 239 1.3E-24 T 29-03-2018 CVS48_RS23955 c664410597ea0b93d6298c87399cd648 244 SUPERFAMILY SSF100950 6 234 1.91E-50 T 29-03-2018 CVS48_RS23955 c664410597ea0b93d6298c87399cd648 244 SMART SM00882 9 202 1.4E-6 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS23955 c664410597ea0b93d6298c87399cd648 244 Pfam PF01144 Coenzyme A transferase 15 170 3.1E-13 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS19125 e61a3ca3ab85242cc9c0fd568dbb89bc 405 SUPERFAMILY SSF52172 10 153 1.42E-20 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS19125 e61a3ca3ab85242cc9c0fd568dbb89bc 405 Pfam PF00563 EAL domain 160 392 3.2E-58 T 29-03-2018 IPR001633 EAL domain CVS48_RS19125 e61a3ca3ab85242cc9c0fd568dbb89bc 405 SMART SM00052 151 397 4.5E-55 T 29-03-2018 IPR001633 EAL domain CVS48_RS19125 e61a3ca3ab85242cc9c0fd568dbb89bc 405 Pfam PF00072 Response regulator receiver domain 12 134 2.5E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19125 e61a3ca3ab85242cc9c0fd568dbb89bc 405 SMART SM00448 10 133 5.2E-10 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19125 e61a3ca3ab85242cc9c0fd568dbb89bc 405 Gene3D G3DSA:3.20.20.450 150 399 2.8E-68 T 29-03-2018 IPR001633 EAL domain CVS48_RS19125 e61a3ca3ab85242cc9c0fd568dbb89bc 405 Gene3D G3DSA:3.40.50.2300 8 149 2.1E-21 T 29-03-2018 CVS48_RS19125 e61a3ca3ab85242cc9c0fd568dbb89bc 405 SUPERFAMILY SSF141868 163 404 2.88E-63 T 29-03-2018 IPR001633 EAL domain CVS48_RS01945 ca96ff08c81d1e02c972d305fd5aefbd 255 Gene3D G3DSA:3.90.226.10 4 212 1.8E-61 T 29-03-2018 CVS48_RS01945 ca96ff08c81d1e02c972d305fd5aefbd 255 Gene3D G3DSA:1.10.12.10 213 255 5.7E-17 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS01945 ca96ff08c81d1e02c972d305fd5aefbd 255 SUPERFAMILY SSF52096 1 254 1.06E-79 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS01945 ca96ff08c81d1e02c972d305fd5aefbd 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS01945 ca96ff08c81d1e02c972d305fd5aefbd 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 254 6.0E-58 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 SUPERFAMILY SSF50447 165 288 1.87E-29 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 176 1.6E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 SUPERFAMILY SSF54980 292 370 1.33E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 Gene3D G3DSA:3.30.70.240 390 549 2.6E-27 T 29-03-2018 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 300.843 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 Gene3D G3DSA:3.40.50.300 1 190 6.7E-37 T 29-03-2018 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 Pfam PF06421 GTP-binding protein LepA C-terminus 487 593 2.8E-48 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 SUPERFAMILY SSF54980 399 493 2.35E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 PRINTS PR00315 GTP-binding elongation factor signature 6 19 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 PRINTS PR00315 GTP-binding elongation factor signature 49 57 1.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 Gene3D G3DSA:2.40.30.10 191 287 5.3E-22 T 29-03-2018 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 Pfam PF03144 Elongation factor Tu domain 2 205 275 2.0E-10 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 9.5E-54 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 TIGRFAM TIGR01393 lepA: elongation factor 4 3 595 1.4E-297 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 SMART SM00838 398 486 0.0013 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 Gene3D G3DSA:3.30.70.870 288 367 3.8E-27 T 29-03-2018 CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 SUPERFAMILY SSF52540 2 205 6.47E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28275 478f987fec93138f726175e06c1715a7 597 Pfam PF00679 Elongation factor G C-terminus 399 479 2.3E-22 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CVS48_RS11725 592d5e5f5f14529b9afee18c67752f92 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 94 4.8E-16 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS11725 592d5e5f5f14529b9afee18c67752f92 159 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 37 78 1.4E-12 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS11725 592d5e5f5f14529b9afee18c67752f92 159 SUPERFAMILY SSF69118 4 145 9.64E-43 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS11725 592d5e5f5f14529b9afee18c67752f92 159 Gene3D G3DSA:1.20.1290.10 1 152 5.3E-39 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS05435 2b143bcb5e0e988def072f2ba21ca813 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 256 4.5E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05435 2b143bcb5e0e988def072f2ba21ca813 266 Gene3D G3DSA:1.10.3720.10 2 254 1.8E-36 T 29-03-2018 CVS48_RS05435 2b143bcb5e0e988def072f2ba21ca813 266 SUPERFAMILY SSF161098 7 265 4.06E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS23910 d9113b5a07cf1307cbf15bbbbf3c2696 405 SUPERFAMILY SSF142764 5 398 5.23E-83 T 29-03-2018 CVS48_RS23910 d9113b5a07cf1307cbf15bbbbf3c2696 405 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 237 391 1.5E-17 T 29-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain CVS48_RS23910 d9113b5a07cf1307cbf15bbbbf3c2696 405 Pfam PF07005 Putative sugar-binding N-terminal domain 5 221 2.3E-49 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CVS48_RS23910 d9113b5a07cf1307cbf15bbbbf3c2696 405 Gene3D G3DSA:3.40.50.10840 4 231 5.2E-57 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CVS48_RS05095 3fb67391fb42ba211fe62a67f5b69f09 225 Pfam PF01634 ATP phosphoribosyltransferase 59 215 1.1E-48 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CVS48_RS05095 3fb67391fb42ba211fe62a67f5b69f09 225 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 10 198 1.3E-59 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CVS48_RS05095 3fb67391fb42ba211fe62a67f5b69f09 225 SUPERFAMILY SSF53850 9 219 2.82E-65 T 29-03-2018 CVS48_RS05095 3fb67391fb42ba211fe62a67f5b69f09 225 Gene3D G3DSA:3.40.190.10 5 130 1.0E-39 T 29-03-2018 CVS48_RS05095 3fb67391fb42ba211fe62a67f5b69f09 225 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 9 222 54.945 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CVS48_RS05095 3fb67391fb42ba211fe62a67f5b69f09 225 Gene3D G3DSA:3.40.190.10 131 223 9.5E-21 T 29-03-2018 CVS48_RS05095 3fb67391fb42ba211fe62a67f5b69f09 225 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 157 178 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CVS48_RS18800 a790107ff521ca89f71c47bbf7dc077a 366 Gene3D G3DSA:2.40.110.10 65 191 1.1E-10 T 29-03-2018 CVS48_RS18800 a790107ff521ca89f71c47bbf7dc077a 366 Gene3D G3DSA:1.20.140.10 192 356 2.3E-7 T 29-03-2018 CVS48_RS18800 a790107ff521ca89f71c47bbf7dc077a 366 SUPERFAMILY SSF56645 39 196 1.26E-16 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS18800 a790107ff521ca89f71c47bbf7dc077a 366 SUPERFAMILY SSF47203 252 339 2.86E-5 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS07045 4cbce75eaf429710de3402b3c1ae2a3c 436 Pfam PF00202 Aminotransferase class-III 37 341 4.4E-37 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS07045 4cbce75eaf429710de3402b3c1ae2a3c 436 Gene3D G3DSA:3.90.1150.10 301 410 0.0016 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS07045 4cbce75eaf429710de3402b3c1ae2a3c 436 Gene3D G3DSA:3.90.1150.10 1 166 2.9E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS07045 4cbce75eaf429710de3402b3c1ae2a3c 436 SUPERFAMILY SSF53383 5 408 3.5E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS07045 4cbce75eaf429710de3402b3c1ae2a3c 436 Gene3D G3DSA:3.40.640.10 167 300 1.9E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS16795 1d46ed84dc97bc32c2b6db831a052ca9 166 SMART SM00260 14 153 1.7E-40 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS16795 1d46ed84dc97bc32c2b6db831a052ca9 166 Gene3D G3DSA:2.30.30.40 96 147 1.7E-17 T 29-03-2018 CVS48_RS16795 1d46ed84dc97bc32c2b6db831a052ca9 166 SUPERFAMILY SSF50341 18 158 1.01E-37 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS16795 1d46ed84dc97bc32c2b6db831a052ca9 166 Gene3D G3DSA:2.40.50.180 37 95 2.7E-17 T 29-03-2018 CVS48_RS16795 1d46ed84dc97bc32c2b6db831a052ca9 166 Pfam PF01584 CheW-like domain 18 155 1.7E-35 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CVS48_RS06090 7e294cbb57b436ae247302cee8eb90e5 528 Gene3D G3DSA:3.40.190.10 181 302 2.9E-38 T 29-03-2018 CVS48_RS06090 7e294cbb57b436ae247302cee8eb90e5 528 Gene3D G3DSA:3.10.105.10 303 499 5.8E-50 T 29-03-2018 CVS48_RS06090 7e294cbb57b436ae247302cee8eb90e5 528 SUPERFAMILY SSF53850 31 510 2.35E-132 T 29-03-2018 CVS48_RS06090 7e294cbb57b436ae247302cee8eb90e5 528 Gene3D G3DSA:3.90.76.10 38 180 4.5E-36 T 29-03-2018 CVS48_RS06090 7e294cbb57b436ae247302cee8eb90e5 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 438 1.2E-96 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS06090 7e294cbb57b436ae247302cee8eb90e5 528 PIRSF PIRSF002741 24 526 2.9E-108 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS22685 eb87211c1f75104f8f86bc27845a3d6e 276 SUPERFAMILY SSF51621 3 196 1.85E-85 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS22685 eb87211c1f75104f8f86bc27845a3d6e 276 Gene3D G3DSA:3.20.20.70 4 252 4.0E-127 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS22685 eb87211c1f75104f8f86bc27845a3d6e 276 PIRSF PIRSF034452 1 276 7.4E-152 T 29-03-2018 IPR009215 TIM-barrel domain, IGPS-like CVS48_RS22685 eb87211c1f75104f8f86bc27845a3d6e 276 Pfam PF09370 Phosphoenolpyruvate hydrolase-like 9 274 2.2E-132 T 29-03-2018 IPR009215 TIM-barrel domain, IGPS-like CVS48_RS22685 eb87211c1f75104f8f86bc27845a3d6e 276 Gene3D G3DSA:1.20.5.460 253 274 1.1E-11 T 29-03-2018 CVS48_RS19955 c505e69bd19140668be830a6df8416d4 374 PIRSF PIRSF033093 1 371 8.1E-113 T 29-03-2018 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type CVS48_RS19955 c505e69bd19140668be830a6df8416d4 374 SUPERFAMILY SSF56300 4 299 5.77E-37 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS19955 c505e69bd19140668be830a6df8416d4 374 Pfam PF00149 Calcineurin-like phosphoesterase 3 113 1.1E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS19955 c505e69bd19140668be830a6df8416d4 374 Gene3D G3DSA:3.60.21.10 2 251 9.1E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS08455 326f57de80a19fec19e5ff7d330b7df0 202 Pfam PF01464 Transglycosylase SLT domain 27 130 2.2E-20 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CVS48_RS08455 326f57de80a19fec19e5ff7d330b7df0 202 SUPERFAMILY SSF53955 19 139 5.63E-35 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS08455 326f57de80a19fec19e5ff7d330b7df0 202 Gene3D G3DSA:1.10.530.10 20 189 6.5E-22 T 29-03-2018 CVS48_RS24980 3e53f22393a93a3683bf56e2d4721338 837 Pfam PF13954 PapC N-terminal domain 2 151 1.4E-32 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 CVS48_RS24980 3e53f22393a93a3683bf56e2d4721338 837 Pfam PF00577 Outer membrane usher protein 167 724 1.1E-152 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS24980 3e53f22393a93a3683bf56e2d4721338 837 Pfam PF13953 PapC C-terminal domain 739 802 3.3E-16 T 29-03-2018 IPR025949 PapC-like, C-terminal domain CVS48_RS24980 3e53f22393a93a3683bf56e2d4721338 837 SUPERFAMILY SSF141729 25 143 4.45E-21 T 29-03-2018 CVS48_RS16625 4d915933ce2da9a82fc7c135a8acb06b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 57 4.3E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16625 4d915933ce2da9a82fc7c135a8acb06b 301 SUPERFAMILY SSF46785 1 79 2.51E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16625 4d915933ce2da9a82fc7c135a8acb06b 301 Gene3D G3DSA:3.40.190.10 87 172 2.9E-10 T 29-03-2018 CVS48_RS16625 4d915933ce2da9a82fc7c135a8acb06b 301 Gene3D G3DSA:3.40.190.10 173 259 1.1E-21 T 29-03-2018 CVS48_RS16625 4d915933ce2da9a82fc7c135a8acb06b 301 Gene3D G3DSA:1.10.10.10 1 78 8.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16625 4d915933ce2da9a82fc7c135a8acb06b 301 SUPERFAMILY SSF53850 84 289 7.78E-35 T 29-03-2018 CVS48_RS16625 4d915933ce2da9a82fc7c135a8acb06b 301 Pfam PF03466 LysR substrate binding domain 83 287 3.8E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS06140 4fa2e72392b6bfbb8559b6d596621182 351 Pfam PF05145 Transition state regulatory protein AbrB 38 346 3.1E-82 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CVS48_RS06140 4fa2e72392b6bfbb8559b6d596621182 351 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 190 345 7.4E-33 T 29-03-2018 IPR017516 AbrB duplication CVS48_RS06140 4fa2e72392b6bfbb8559b6d596621182 351 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 19 170 1.1E-34 T 29-03-2018 IPR017516 AbrB duplication CVS48_RS06140 4fa2e72392b6bfbb8559b6d596621182 351 PIRSF PIRSF038991 4 351 2.7E-80 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 SUPERFAMILY SSF69864 190 434 1.01E-76 T 29-03-2018 CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 444 68.678 T 29-03-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 1.6E-158 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 Gene3D G3DSA:3.90.1260.10 179 374 1.4E-58 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 Gene3D G3DSA:3.40.50.620 3 178 1.3E-17 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 SUPERFAMILY SSF52402 4 185 1.16E-33 T 29-03-2018 CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 Pfam PF00764 Arginosuccinate synthase 16 394 1.0E-59 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS26380 a26a8360e1949b9229e6a4846b86597d 446 Gene3D G3DSA:1.10.287.400 378 437 7.1E-30 T 29-03-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS13325 71e8ed7c4956a245eba4e619f8da330d 262 SMART SM00382 35 233 1.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13325 71e8ed7c4956a245eba4e619f8da330d 262 Gene3D G3DSA:3.40.50.300 7 262 2.9E-59 T 29-03-2018 CVS48_RS13325 71e8ed7c4956a245eba4e619f8da330d 262 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13325 71e8ed7c4956a245eba4e619f8da330d 262 Pfam PF00005 ABC transporter 27 184 1.1E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13325 71e8ed7c4956a245eba4e619f8da330d 262 TIGRFAM TIGR02323 CP_lyasePhnK: phosphonate C-P lyase system protein PhnK 8 260 1.1E-110 T 29-03-2018 IPR012700 Phosphonate C-P lyase system, PhnK CVS48_RS13325 71e8ed7c4956a245eba4e619f8da330d 262 SUPERFAMILY SSF52540 5 258 9.15E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13325 71e8ed7c4956a245eba4e619f8da330d 262 PIRSF PIRSF037116 2 262 6.9E-134 T 29-03-2018 IPR012700 Phosphonate C-P lyase system, PhnK CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 483 1.5E-56 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 Pfam PF02203 Tar ligand binding domain homologue 1 168 7.7E-19 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 Gene3D G3DSA:1.10.287.1060 236 326 0.019 T 29-03-2018 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 SMART SM00304 215 267 6.9E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 SMART SM00283 268 515 8.7E-99 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 SUPERFAMILY SSF47170 27 180 5.23E-15 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 443 472 2.8E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 2.8E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 289 318 2.8E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 395 424 2.8E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 366 393 2.8E-63 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 Gene3D G3DSA:1.20.120.30 23 187 4.3E-21 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 Gene3D G3DSA:1.10.287.950 327 519 6.5E-51 T 29-03-2018 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 Pfam PF00672 HAMP domain 215 263 4.0E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS16920 66299ff63899f2d63ab488e6eb0a4f2f 622 SUPERFAMILY SSF58104 235 520 1.44E-77 T 29-03-2018 CVS48_RS28490 5d7d0a58f2c7e6314a6f00bbb6e887e4 341 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 40 317 3.4E-67 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CVS48_RS28490 5d7d0a58f2c7e6314a6f00bbb6e887e4 341 SUPERFAMILY SSF53850 37 332 1.43E-78 T 29-03-2018 CVS48_RS28490 5d7d0a58f2c7e6314a6f00bbb6e887e4 341 Gene3D G3DSA:3.40.190.10 32 166 2.8E-21 T 29-03-2018 CVS48_RS28490 5d7d0a58f2c7e6314a6f00bbb6e887e4 341 Gene3D G3DSA:3.40.190.10 167 329 7.1E-33 T 29-03-2018 CVS48_RS03570 b12e999c7e9a71ed9e5bf1158111d7c2 253 Pfam PF04170 NlpE N-terminal domain 134 214 1.1E-4 T 29-03-2018 IPR007298 Copper resistance lipoprotein NlpE CVS48_RS16705 0d52be042739608c90cb98ec58f5c91c 258 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 69 221 1.2E-12 T 29-03-2018 IPR008884 Macrocin-O-methyltransferase CVS48_RS16705 0d52be042739608c90cb98ec58f5c91c 258 Gene3D G3DSA:3.40.50.150 54 252 1.3E-7 T 29-03-2018 CVS48_RS16705 0d52be042739608c90cb98ec58f5c91c 258 SUPERFAMILY SSF53335 157 226 5.55E-8 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS16705 0d52be042739608c90cb98ec58f5c91c 258 SUPERFAMILY SSF53335 69 114 5.55E-8 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS15640 c45d7028e89596a8957f8de2f680891a 427 Gene3D G3DSA:3.40.630.10 255 423 9.6E-23 T 29-03-2018 CVS48_RS15640 c45d7028e89596a8957f8de2f680891a 427 Gene3D G3DSA:3.40.630.10 13 254 1.1E-36 T 29-03-2018 CVS48_RS15640 c45d7028e89596a8957f8de2f680891a 427 Pfam PF01546 Peptidase family M20/M25/M40 87 417 3.7E-28 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS15640 c45d7028e89596a8957f8de2f680891a 427 SUPERFAMILY SSF55031 222 340 6.63E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS15640 c45d7028e89596a8957f8de2f680891a 427 PIRSF PIRSF001235 15 425 2.1E-133 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CVS48_RS15640 c45d7028e89596a8957f8de2f680891a 427 SUPERFAMILY SSF53187 9 232 7.71E-85 T 29-03-2018 CVS48_RS15640 c45d7028e89596a8957f8de2f680891a 427 SUPERFAMILY SSF53187 348 421 7.71E-85 T 29-03-2018 CVS48_RS15640 c45d7028e89596a8957f8de2f680891a 427 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 17 420 7.7E-111 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CVS48_RS22115 8c97b0f3feed00a12c4be45839cb3c09 485 Pfam PF00083 Sugar (and other) transporter 66 446 2.3E-28 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS22115 8c97b0f3feed00a12c4be45839cb3c09 485 Gene3D G3DSA:1.20.1250.20 27 226 1.4E-26 T 29-03-2018 CVS48_RS22115 8c97b0f3feed00a12c4be45839cb3c09 485 Gene3D G3DSA:1.20.1250.20 246 462 5.1E-19 T 29-03-2018 CVS48_RS22115 8c97b0f3feed00a12c4be45839cb3c09 485 SUPERFAMILY SSF103473 22 454 2.09E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 SUPERFAMILY SSF46785 1 86 7.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 Gene3D G3DSA:1.10.10.10 1 83 5.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 Pfam PF03466 LysR substrate binding domain 87 290 2.5E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 SUPERFAMILY SSF53850 87 291 1.49E-35 T 29-03-2018 CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 Gene3D G3DSA:3.40.190.10 88 174 1.4E-16 T 29-03-2018 CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20955 6b2b1d8f7c38ea8c1f1d93da04bd891c 298 Gene3D G3DSA:3.40.190.10 175 267 1.3E-25 T 29-03-2018 CVS48_RS15065 61c784017bc1def2c303f0aa1eaf574d 354 PRINTS PR01270 Histone deacetylase superfamily signature 198 213 1.1E-14 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS15065 61c784017bc1def2c303f0aa1eaf574d 354 PRINTS PR01270 Histone deacetylase superfamily signature 166 189 1.1E-14 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS15065 61c784017bc1def2c303f0aa1eaf574d 354 PRINTS PR01270 Histone deacetylase superfamily signature 284 294 1.1E-14 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS15065 61c784017bc1def2c303f0aa1eaf574d 354 Gene3D G3DSA:3.40.800.20 1 354 7.7E-80 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS15065 61c784017bc1def2c303f0aa1eaf574d 354 Pfam PF00850 Histone deacetylase domain 48 346 1.1E-65 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS15065 61c784017bc1def2c303f0aa1eaf574d 354 SUPERFAMILY SSF52768 4 77 1.97E-83 T 29-03-2018 CVS48_RS15065 61c784017bc1def2c303f0aa1eaf574d 354 SUPERFAMILY SSF52768 114 349 1.97E-83 T 29-03-2018 CVS48_RS01310 6c3799f9e4b90da2d95fef636bcf6135 271 Gene3D G3DSA:3.40.980.10 5 184 1.4E-39 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS01310 6c3799f9e4b90da2d95fef636bcf6135 271 SMART SM00852 11 184 4.5E-29 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS01310 6c3799f9e4b90da2d95fef636bcf6135 271 SUPERFAMILY SSF53218 9 219 9.68E-34 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS01310 6c3799f9e4b90da2d95fef636bcf6135 271 Pfam PF00994 Probable molybdopterin binding domain 12 177 9.9E-24 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS04165 acebd5ef88c26823b331c2ab40e7466d 320 Gene3D G3DSA:3.40.190.10 121 230 1.3E-10 T 29-03-2018 CVS48_RS04165 acebd5ef88c26823b331c2ab40e7466d 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 315 3.4E-89 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04165 acebd5ef88c26823b331c2ab40e7466d 320 SUPERFAMILY SSF53850 108 286 1.11E-11 T 29-03-2018 CVS48_RS04165 acebd5ef88c26823b331c2ab40e7466d 320 PIRSF PIRSF017082 1 319 1.1E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS12615 9f9da6dabd3dba55f375e55e3e7bc9c7 201 SMART SM00014 58 168 2.1E-13 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS12615 9f9da6dabd3dba55f375e55e3e7bc9c7 201 SUPERFAMILY SSF48317 5 174 4.06E-30 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS12615 9f9da6dabd3dba55f375e55e3e7bc9c7 201 Gene3D G3DSA:1.20.144.10 3 190 1.5E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS12615 9f9da6dabd3dba55f375e55e3e7bc9c7 201 Pfam PF01569 PAP2 superfamily 59 172 2.7E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS22905 abd67887c2a0e6c6aa4e69c27398a1fd 462 Pfam PF07687 Peptidase dimerisation domain 250 342 1.2E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS22905 abd67887c2a0e6c6aa4e69c27398a1fd 462 Pfam PF01546 Peptidase family M20/M25/M40 118 450 6.0E-31 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS22905 abd67887c2a0e6c6aa4e69c27398a1fd 462 SUPERFAMILY SSF55031 249 356 9.03E-29 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS22905 abd67887c2a0e6c6aa4e69c27398a1fd 462 SUPERFAMILY SSF53187 364 456 8.57E-85 T 29-03-2018 CVS48_RS22905 abd67887c2a0e6c6aa4e69c27398a1fd 462 SUPERFAMILY SSF53187 47 262 8.57E-85 T 29-03-2018 CVS48_RS22905 abd67887c2a0e6c6aa4e69c27398a1fd 462 Gene3D G3DSA:3.40.630.10 305 462 4.4E-22 T 29-03-2018 CVS48_RS22905 abd67887c2a0e6c6aa4e69c27398a1fd 462 Gene3D G3DSA:3.40.630.10 37 304 1.1E-53 T 29-03-2018 CVS48_RS22905 abd67887c2a0e6c6aa4e69c27398a1fd 462 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 60 441 1.2E-105 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS22905 abd67887c2a0e6c6aa4e69c27398a1fd 462 PIRSF PIRSF005962 44 459 1.9E-119 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS12560 8e8eb8edff787953baa6c7b480e7c82a 876 Pfam PF07715 TonB-dependent Receptor Plug Domain 162 260 3.3E-10 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS12560 8e8eb8edff787953baa6c7b480e7c82a 876 Gene3D G3DSA:2.170.130.10 156 274 7.2E-15 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS12560 8e8eb8edff787953baa6c7b480e7c82a 876 Pfam PF00593 TonB dependent receptor 367 875 9.7E-63 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12560 8e8eb8edff787953baa6c7b480e7c82a 876 SUPERFAMILY SSF56935 533 875 1.34E-97 T 29-03-2018 CVS48_RS12560 8e8eb8edff787953baa6c7b480e7c82a 876 SUPERFAMILY SSF56935 157 504 1.34E-97 T 29-03-2018 CVS48_RS12560 8e8eb8edff787953baa6c7b480e7c82a 876 Gene3D G3DSA:2.40.170.20 275 875 4.0E-75 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12560 8e8eb8edff787953baa6c7b480e7c82a 876 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 157 876 9.7E-166 T 29-03-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 CVS48_RS12560 8e8eb8edff787953baa6c7b480e7c82a 876 SMART SM00965 85 136 3.5E-10 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS12560 8e8eb8edff787953baa6c7b480e7c82a 876 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 188 876 1.2E-174 T 29-03-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 Pfam PF00355 Rieske [2Fe-2S] domain 38 124 1.1E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 193 411 7.5E-18 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 SUPERFAMILY SSF50022 9 163 7.07E-44 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 SUPERFAMILY SSF55961 172 410 8.63E-52 T 29-03-2018 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 81 104 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 95 115 9.2E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 74 94 9.2E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 186 208 9.2E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 22 47 9.2E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 53 68 9.2E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 147 173 9.2E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 Gene3D G3DSA:3.90.380.10 154 412 1.9E-49 T 29-03-2018 CVS48_RS01680 0934e033fd1432953d1db3de13b37613 412 Gene3D G3DSA:2.102.10.10 36 153 1.4E-25 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 584 1.1E-18 T 29-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 SUPERFAMILY SSF47203 289 465 7.09E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 Gene3D G3DSA:1.20.140.10 297 464 5.4E-44 T 29-03-2018 CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 270 8.0E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 35 155 1.1E-11 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 Gene3D G3DSA:2.40.110.10 159 282 6.3E-26 T 29-03-2018 CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 449 1.5E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 SUPERFAMILY SSF56645 34 280 1.18E-60 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 Gene3D G3DSA:1.10.540.10 15 158 1.3E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS15565 d0bbe8a451d213da6b2b797447a90462 589 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 2 33 7.6E-13 T 29-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CVS48_RS25020 9ed6d7eb52012bf921e73b7e249b6024 556 SUPERFAMILY SSF52518 6 189 8.96E-45 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS25020 9ed6d7eb52012bf921e73b7e249b6024 556 SUPERFAMILY SSF52467 162 350 2.17E-29 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS25020 9ed6d7eb52012bf921e73b7e249b6024 556 Gene3D G3DSA:3.40.50.970 352 540 1.7E-29 T 29-03-2018 CVS48_RS25020 9ed6d7eb52012bf921e73b7e249b6024 556 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 326 5.6E-16 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS25020 9ed6d7eb52012bf921e73b7e249b6024 556 SUPERFAMILY SSF52518 364 535 5.2E-38 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS25020 9ed6d7eb52012bf921e73b7e249b6024 556 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 177 1.1E-47 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS25020 9ed6d7eb52012bf921e73b7e249b6024 556 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 533 2.4E-29 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS25020 9ed6d7eb52012bf921e73b7e249b6024 556 Gene3D G3DSA:3.40.50.1220 198 351 8.5E-25 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS25020 9ed6d7eb52012bf921e73b7e249b6024 556 Gene3D G3DSA:3.40.50.970 2 197 1.5E-44 T 29-03-2018 CVS48_RS25565 cbdfd3bbe3ecc91c842cae65896ecafc 383 SUPERFAMILY SSF53901 230 369 1.22E-23 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS25565 cbdfd3bbe3ecc91c842cae65896ecafc 383 Gene3D G3DSA:3.40.47.10 141 373 4.8E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS25565 cbdfd3bbe3ecc91c842cae65896ecafc 383 Gene3D G3DSA:3.40.47.10 12 120 0.007 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS25565 cbdfd3bbe3ecc91c842cae65896ecafc 383 SUPERFAMILY SSF53901 11 222 4.39E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS14135 ddb04af74b365aa866e1a585af0c2edf 288 Gene3D G3DSA:1.10.3470.10 1 279 3.6E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS14135 ddb04af74b365aa866e1a585af0c2edf 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 3.4E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS24580 945dfdd05640c1744611ba8303cf881e 80 SUPERFAMILY SSF47413 10 64 2.82E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS24580 945dfdd05640c1744611ba8303cf881e 80 Gene3D G3DSA:3.30.240.10 1 69 8.7E-12 T 29-03-2018 CVS48_RS24580 945dfdd05640c1744611ba8303cf881e 80 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 13 66 1.7E-16 T 29-03-2018 IPR031856 Putative bacterial antitoxin YdaS CVS48_RS07555 0339b6b9b3f396f25e344b060458e9ed 265 SUPERFAMILY SSF52540 13 262 1.11E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07555 0339b6b9b3f396f25e344b060458e9ed 265 Gene3D G3DSA:3.40.50.300 9 263 1.2E-53 T 29-03-2018 CVS48_RS07555 0339b6b9b3f396f25e344b060458e9ed 265 Pfam PF00005 ABC transporter 30 191 2.1E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07555 0339b6b9b3f396f25e344b060458e9ed 265 SMART SM00382 39 240 1.2E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS07555 0339b6b9b3f396f25e344b060458e9ed 265 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 240 262 3.5E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 9.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 9.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 9.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 Gene3D G3DSA:3.40.50.720 13 172 8.6E-46 T 29-03-2018 CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 257 2.1E-52 T 29-03-2018 CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.4E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 1.4E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 1.4E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.4E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 1.4E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.4E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 Gene3D G3DSA:3.40.50.720 173 258 2.0E-19 T 29-03-2018 CVS48_RS25030 288483548500a08987d6abd1dcaf529e 260 SUPERFAMILY SSF51735 12 259 4.71E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS26860 bea0a515d182926e34e6aa455e1591e2 558 Gene3D G3DSA:1.20.1250.20 14 232 1.9E-26 T 29-03-2018 CVS48_RS26860 bea0a515d182926e34e6aa455e1591e2 558 SUPERFAMILY SSF103473 455 554 6.67E-11 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS26860 bea0a515d182926e34e6aa455e1591e2 558 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS26860 bea0a515d182926e34e6aa455e1591e2 558 Gene3D G3DSA:1.20.1250.20 233 557 5.2E-32 T 29-03-2018 CVS48_RS26860 bea0a515d182926e34e6aa455e1591e2 558 Pfam PF00083 Sugar (and other) transporter 27 240 1.6E-27 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS26860 bea0a515d182926e34e6aa455e1591e2 558 SUPERFAMILY SSF103473 18 341 6.15E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS06170 2f5904fc4b42a45529756323079c51f1 307 SMART SM00470 40 133 1.3E-34 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CVS48_RS06170 2f5904fc4b42a45529756323079c51f1 307 Gene3D G3DSA:1.10.10.730 134 181 1.1E-20 T 29-03-2018 CVS48_RS06170 2f5904fc4b42a45529756323079c51f1 307 SUPERFAMILY SSF109709 126 232 1.99E-33 T 29-03-2018 CVS48_RS06170 2f5904fc4b42a45529756323079c51f1 307 Gene3D G3DSA:3.90.1530.10 27 133 1.5E-34 T 29-03-2018 CVS48_RS06170 2f5904fc4b42a45529756323079c51f1 307 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 40 218 7.4E-57 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CVS48_RS06170 2f5904fc4b42a45529756323079c51f1 307 SUPERFAMILY SSF110849 41 135 4.45E-28 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CVS48_RS06170 2f5904fc4b42a45529756323079c51f1 307 Pfam PF02195 ParB-like nuclease domain 42 133 9.2E-25 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CVS48_RS06670 b95a95f46bfffc6a4214b05ea8888927 272 SUPERFAMILY SSF144059 10 271 6.41E-74 T 29-03-2018 CVS48_RS06670 b95a95f46bfffc6a4214b05ea8888927 272 PIRSF PIRSF029288 8 272 1.1E-82 T 29-03-2018 IPR009211 Predicted virulence protein, SciE type CVS48_RS06670 b95a95f46bfffc6a4214b05ea8888927 272 Pfam PF07024 ImpE protein 147 270 2.6E-39 T 29-03-2018 IPR009211 Predicted virulence protein, SciE type CVS48_RS06670 b95a95f46bfffc6a4214b05ea8888927 272 Gene3D G3DSA:1.25.20.10 10 222 1.7E-4 T 29-03-2018 CVS48_RS02810 132994d404d660b05e072293b997a86d 88 Gene3D G3DSA:1.10.1220.10 30 88 3.2E-5 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CVS48_RS13355 59c73a907460677d04e3d8951d9c1811 299 Gene3D G3DSA:2.120.10.30 2 299 4.6E-29 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS13355 59c73a907460677d04e3d8951d9c1811 299 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 17 270 8.1E-45 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CVS48_RS13355 59c73a907460677d04e3d8951d9c1811 299 SUPERFAMILY SSF63829 7 293 6.76E-48 T 29-03-2018 CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 239 247 - T 29-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 Gene3D G3DSA:2.40.50.140 419 541 7.6E-24 T 29-03-2018 CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 2 539 3.0E-182 T 29-03-2018 IPR026333 ATP-dependent DNA ligase, PP_1105 family CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 Pfam PF04679 ATP dependent DNA ligase C terminal region 436 525 2.8E-9 T 29-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 SUPERFAMILY SSF117018 4 179 4.84E-5 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 SUPERFAMILY SSF50249 420 540 4.11E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 Pfam PF01068 ATP dependent DNA ligase domain 234 415 1.5E-32 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 Pfam PF04675 DNA ligase N terminus 3 173 9.3E-19 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 Gene3D G3DSA:3.30.470.30 244 349 1.8E-27 T 29-03-2018 CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 SUPERFAMILY SSF56091 213 415 3.6E-54 T 29-03-2018 CVS48_RS18780 c008964cd9040b96638146020a83ccee 541 Gene3D G3DSA:3.30.1490.70 350 416 7.5E-21 T 29-03-2018 CVS48_RS03635 0534b4111f1990e153458b950da51b04 403 Pfam PF13378 Enolase C-terminal domain-like 142 377 2.0E-37 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS03635 0534b4111f1990e153458b950da51b04 403 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CVS48_RS03635 0534b4111f1990e153458b950da51b04 403 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 110 5.6E-31 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CVS48_RS03635 0534b4111f1990e153458b950da51b04 403 SUPERFAMILY SSF51604 98 386 9.96E-75 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS03635 0534b4111f1990e153458b950da51b04 403 Gene3D G3DSA:3.20.20.120 113 375 2.3E-55 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS03635 0534b4111f1990e153458b950da51b04 403 Gene3D G3DSA:3.30.390.10 1 112 2.4E-35 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS03635 0534b4111f1990e153458b950da51b04 403 SMART SM00922 128 257 7.0E-16 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CVS48_RS03635 0534b4111f1990e153458b950da51b04 403 SUPERFAMILY SSF54826 1 112 1.47E-33 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS16170 b276afec78599fbd444baba75504acf3 210 Pfam PF11612 Type II secretion system (T2SS), protein J 70 197 3.3E-7 T 29-03-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 CVS48_RS16170 b276afec78599fbd444baba75504acf3 210 SUPERFAMILY SSF54523 51 207 5.1E-10 T 29-03-2018 CVS48_RS16170 b276afec78599fbd444baba75504acf3 210 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 17 39 3.4E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS16170 b276afec78599fbd444baba75504acf3 210 Gene3D G3DSA:3.10.610.10 50 156 1.2E-10 T 29-03-2018 CVS48_RS16170 b276afec78599fbd444baba75504acf3 210 Pfam PF07963 Prokaryotic N-terminal methylation motif 15 39 2.2E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS16170 b276afec78599fbd444baba75504acf3 210 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 18 38 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS11510 a87067f019fcd03274791457282aaac8 272 SUPERFAMILY SSF53474 11 267 6.33E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11510 a87067f019fcd03274791457282aaac8 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 229 7.6E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11510 a87067f019fcd03274791457282aaac8 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 7.6E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11510 a87067f019fcd03274791457282aaac8 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 7.6E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11510 a87067f019fcd03274791457282aaac8 272 Pfam PF12697 Alpha/beta hydrolase family 26 264 2.0E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11510 a87067f019fcd03274791457282aaac8 272 Gene3D G3DSA:3.40.50.1820 9 270 2.7E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS27945 93bc2947736acc2438d60826fb330e8f 627 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 442 453 - T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS27945 93bc2947736acc2438d60826fb330e8f 627 Gene3D G3DSA:3.40.50.150 342 591 4.2E-33 T 29-03-2018 CVS48_RS27945 93bc2947736acc2438d60826fb330e8f 627 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 547 553 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CVS48_RS27945 93bc2947736acc2438d60826fb330e8f 627 Pfam PF01170 Putative RNA methylase family UPF0020 409 613 1.0E-47 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS27945 93bc2947736acc2438d60826fb330e8f 627 Pfam PF02926 THUMP domain 284 400 9.5E-9 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CVS48_RS27945 93bc2947736acc2438d60826fb330e8f 627 SMART SM00981 303 401 1.4E-13 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CVS48_RS27945 93bc2947736acc2438d60826fb330e8f 627 SUPERFAMILY SSF53335 395 464 9.47E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS27945 93bc2947736acc2438d60826fb330e8f 627 SUPERFAMILY SSF53335 501 615 9.47E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS00770 b30d4e11924abfa546adea7418be4d69 214 Gene3D G3DSA:1.20.1170.10 27 198 2.6E-6 T 29-03-2018 CVS48_RS07770 da6e0313ff3d4df18ee9c1632f4b1b93 200 SUPERFAMILY SSF56784 27 184 6.27E-39 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS07770 da6e0313ff3d4df18ee9c1632f4b1b93 200 PIRSF PIRSF006118 17 190 5.8E-60 T 29-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CVS48_RS07770 da6e0313ff3d4df18ee9c1632f4b1b93 200 Pfam PF08282 haloacid dehalogenase-like hydrolase 96 163 5.2E-8 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS07770 da6e0313ff3d4df18ee9c1632f4b1b93 200 Gene3D G3DSA:3.40.50.1000 23 193 3.1E-27 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS07770 da6e0313ff3d4df18ee9c1632f4b1b93 200 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 30 181 3.7E-40 T 29-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CVS48_RS13115 70d1a2fd7e7ef2cfa654184ba0ed3b8e 155 SUPERFAMILY SSF52038 41 129 5.36E-18 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CVS48_RS13115 70d1a2fd7e7ef2cfa654184ba0ed3b8e 155 Pfam PF01337 Barstar (barnase inhibitor) 43 124 7.4E-20 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CVS48_RS13115 70d1a2fd7e7ef2cfa654184ba0ed3b8e 155 Gene3D G3DSA:3.30.370.10 39 135 1.7E-14 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CVS48_RS01895 69b990787d984b0560365112016441d2 506 Gene3D G3DSA:3.40.50.980 7 170 5.0E-39 T 29-03-2018 CVS48_RS01895 69b990787d984b0560365112016441d2 506 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 495 2.2E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS01895 69b990787d984b0560365112016441d2 506 Gene3D G3DSA:2.30.38.10 323 404 3.7E-21 T 29-03-2018 CVS48_RS01895 69b990787d984b0560365112016441d2 506 Pfam PF00501 AMP-binding enzyme 15 411 1.1E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS01895 69b990787d984b0560365112016441d2 506 Gene3D G3DSA:3.30.300.30 405 506 2.1E-25 T 29-03-2018 CVS48_RS01895 69b990787d984b0560365112016441d2 506 SUPERFAMILY SSF56801 7 505 4.32E-136 T 29-03-2018 CVS48_RS01895 69b990787d984b0560365112016441d2 506 Gene3D G3DSA:3.40.50.980 171 322 2.4E-44 T 29-03-2018 CVS48_RS01895 69b990787d984b0560365112016441d2 506 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS25235 a225bc278ccbb0fb6f637e3a66f99c2c 175 SUPERFAMILY SSF46785 17 158 1.43E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25235 a225bc278ccbb0fb6f637e3a66f99c2c 175 SMART SM00347 39 139 3.4E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25235 a225bc278ccbb0fb6f637e3a66f99c2c 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 8.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25235 a225bc278ccbb0fb6f637e3a66f99c2c 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 8.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25235 a225bc278ccbb0fb6f637e3a66f99c2c 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 129 149 8.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25235 a225bc278ccbb0fb6f637e3a66f99c2c 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 8.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25235 a225bc278ccbb0fb6f637e3a66f99c2c 175 Gene3D G3DSA:1.10.10.10 16 135 4.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25235 a225bc278ccbb0fb6f637e3a66f99c2c 175 Gene3D G3DSA:1.10.10.10 136 153 0.35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25235 a225bc278ccbb0fb6f637e3a66f99c2c 175 Pfam PF12802 MarR family 45 103 2.6E-14 T 29-03-2018 CVS48_RS17270 ef488d23512ba603937e5893ac18b61a 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 9.1E-52 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CVS48_RS17270 ef488d23512ba603937e5893ac18b61a 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 290 2.8E-35 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CVS48_RS17270 ef488d23512ba603937e5893ac18b61a 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CVS48_RS17270 ef488d23512ba603937e5893ac18b61a 296 Gene3D G3DSA:3.40.50.720 2 172 7.3E-37 T 29-03-2018 CVS48_RS17270 ef488d23512ba603937e5893ac18b61a 296 SUPERFAMILY SSF48179 162 292 1.47E-39 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS17270 ef488d23512ba603937e5893ac18b61a 296 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 291 4.4E-132 T 29-03-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 CVS48_RS17270 ef488d23512ba603937e5893ac18b61a 296 Gene3D G3DSA:1.10.1040.10 173 296 3.1E-31 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS17270 ef488d23512ba603937e5893ac18b61a 296 SUPERFAMILY SSF51735 3 162 1.45E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS17270 ef488d23512ba603937e5893ac18b61a 296 PIRSF PIRSF000103 1 296 2.6E-80 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CVS48_RS23020 e084018d6716e3678e0baa2d423f6b10 330 SUPERFAMILY SSF48179 195 293 4.51E-23 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS23020 e084018d6716e3678e0baa2d423f6b10 330 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 195 293 1.3E-19 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS23020 e084018d6716e3678e0baa2d423f6b10 330 Gene3D G3DSA:3.40.50.720 2 193 5.9E-42 T 29-03-2018 CVS48_RS23020 e084018d6716e3678e0baa2d423f6b10 330 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 190 1.6E-46 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS23020 e084018d6716e3678e0baa2d423f6b10 330 SUPERFAMILY SSF51735 3 191 1.01E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23020 e084018d6716e3678e0baa2d423f6b10 330 PIRSF PIRSF000105 1 322 2.8E-83 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CVS48_RS23020 e084018d6716e3678e0baa2d423f6b10 330 Gene3D G3DSA:1.10.1040.10 194 298 4.6E-23 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS01315 0703b58f284c0bb09c7f80b7a855ebb5 269 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 30 243 1.5E-18 T 29-03-2018 CVS48_RS13970 8b4d3cd34d74a3e34a2b74b6ab39aa42 154 Pfam PF10027 Predicted integral membrane protein (DUF2269) 6 153 3.7E-57 T 29-03-2018 IPR018729 Protein of unknown function DUF2269, transmembrane CVS48_RS15635 f63e6502153c75c44ee5359a86cf46f1 111 Pfam PF00085 Thioredoxin 5 98 4.6E-5 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CVS48_RS15635 f63e6502153c75c44ee5359a86cf46f1 111 SUPERFAMILY SSF52833 2 104 1.78E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS15635 f63e6502153c75c44ee5359a86cf46f1 111 Gene3D G3DSA:3.40.30.10 1 105 8.2E-10 T 29-03-2018 CVS48_RS12730 42dc03b5f675d5e4b1b7094a6484e54f 234 Gene3D G3DSA:3.40.50.720 1 234 2.9E-54 T 29-03-2018 CVS48_RS12730 42dc03b5f675d5e4b1b7094a6484e54f 234 SUPERFAMILY SSF51735 4 231 4.06E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS12730 42dc03b5f675d5e4b1b7094a6484e54f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.4E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12730 42dc03b5f675d5e4b1b7094a6484e54f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.4E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12730 42dc03b5f675d5e4b1b7094a6484e54f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 2.4E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12730 42dc03b5f675d5e4b1b7094a6484e54f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.4E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12730 42dc03b5f675d5e4b1b7094a6484e54f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.4E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12730 42dc03b5f675d5e4b1b7094a6484e54f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.4E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12730 42dc03b5f675d5e4b1b7094a6484e54f 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 231 6.2E-47 T 29-03-2018 CVS48_RS16945 f1dac1b4cafe6798ab34a7af2ed075d2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 9.0E-22 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CVS48_RS16945 f1dac1b4cafe6798ab34a7af2ed075d2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 9.0E-22 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CVS48_RS16945 f1dac1b4cafe6798ab34a7af2ed075d2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 9.0E-22 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CVS48_RS16945 f1dac1b4cafe6798ab34a7af2ed075d2 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 2.0E-29 T 29-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CVS48_RS16945 f1dac1b4cafe6798ab34a7af2ed075d2 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 4.0E-29 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CVS48_RS16945 f1dac1b4cafe6798ab34a7af2ed075d2 89 PIRSF PIRSF004669 1 89 6.5E-30 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CVS48_RS16570 d98c87c40a4bc9f7b323069ddf43d57f 549 ProSitePatterns PS01130 SLC26A transporters signature. 40 61 - T 29-03-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 CVS48_RS16570 d98c87c40a4bc9f7b323069ddf43d57f 549 SUPERFAMILY SSF52091 433 541 4.91E-16 T 29-03-2018 IPR002645 STAS domain CVS48_RS16570 d98c87c40a4bc9f7b323069ddf43d57f 549 Gene3D G3DSA:3.30.750.24 414 549 1.3E-23 T 29-03-2018 IPR002645 STAS domain CVS48_RS16570 d98c87c40a4bc9f7b323069ddf43d57f 549 Pfam PF00916 Sulfate permease family 12 375 9.0E-86 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CVS48_RS16570 d98c87c40a4bc9f7b323069ddf43d57f 549 Pfam PF01740 STAS domain 430 537 1.1E-14 T 29-03-2018 IPR002645 STAS domain CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 114 131 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 PRINTS PR00069 Aldo-keto reductase signature 25 49 1.9E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 PRINTS PR00069 Aldo-keto reductase signature 81 99 1.9E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 PRINTS PR00069 Aldo-keto reductase signature 149 178 1.9E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 PRINTS PR00069 Aldo-keto reductase signature 186 210 1.9E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 PRINTS PR00069 Aldo-keto reductase signature 114 131 1.9E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 SUPERFAMILY SSF51430 2 257 4.19E-80 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 PIRSF PIRSF000097 1 266 8.1E-69 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 Gene3D G3DSA:3.20.20.100 1 265 1.8E-84 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 29 46 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CVS48_RS04615 956b890b8878f4479de83680874e2eed 268 Pfam PF00248 Aldo/keto reductase family 16 251 4.1E-49 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS18630 4f3f4d31c62803439de62b4aefe4aea6 289 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 286 6.4E-11 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS18630 4f3f4d31c62803439de62b4aefe4aea6 289 Gene3D G3DSA:3.40.50.300 6 284 3.6E-71 T 29-03-2018 CVS48_RS18630 4f3f4d31c62803439de62b4aefe4aea6 289 Pfam PF00005 ABC transporter 30 188 5.7E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS18630 4f3f4d31c62803439de62b4aefe4aea6 289 SUPERFAMILY SSF52540 9 260 1.77E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18630 4f3f4d31c62803439de62b4aefe4aea6 289 SMART SM00382 38 238 1.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS18630 4f3f4d31c62803439de62b4aefe4aea6 289 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 276 1.9E-10 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 Gene3D G3DSA:3.40.50.300 275 541 6.5E-76 T 29-03-2018 CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 Gene3D G3DSA:3.40.50.300 4 273 4.2E-70 T 29-03-2018 CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 Pfam PF00005 ABC transporter 305 453 1.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 Pfam PF00005 ABC transporter 28 185 4.1E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 ProSitePatterns PS00211 ABC transporters family signature. 427 441 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 SMART SM00382 36 235 5.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 SMART SM00382 313 512 2.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 506 532 0.0014 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 269 7.1E-8 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 SUPERFAMILY SSF52540 7 257 7.18E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 SUPERFAMILY SSF52540 278 526 6.53E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS15075 8b6972a9af9568f1e3ef42498f3abb9c 543 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS25810 6ab977546bdc4501cdc7827da079cefc 365 SUPERFAMILY SSF82861 97 177 7.85E-12 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CVS48_RS25810 6ab977546bdc4501cdc7827da079cefc 365 Gene3D G3DSA:2.30.30.60 194 243 3.4E-9 T 29-03-2018 CVS48_RS25810 6ab977546bdc4501cdc7827da079cefc 365 SUPERFAMILY SSF82689 245 347 2.48E-16 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CVS48_RS25810 6ab977546bdc4501cdc7827da079cefc 365 Pfam PF00924 Mechanosensitive ion channel 137 335 4.4E-50 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CVS48_RS25810 6ab977546bdc4501cdc7827da079cefc 365 Gene3D G3DSA:3.30.70.100 247 334 6.6E-14 T 29-03-2018 CVS48_RS25810 6ab977546bdc4501cdc7827da079cefc 365 SUPERFAMILY SSF50182 179 243 2.09E-11 T 29-03-2018 IPR010920 LSM domain CVS48_RS07530 93307e0a1a39232788e5f0d7b81177fc 422 Gene3D G3DSA:3.40.50.980 114 270 4.4E-15 T 29-03-2018 CVS48_RS07530 93307e0a1a39232788e5f0d7b81177fc 422 Pfam PF00501 AMP-binding enzyme 138 287 1.3E-13 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS07530 93307e0a1a39232788e5f0d7b81177fc 422 Gene3D G3DSA:3.30.300.30 325 414 3.3E-5 T 29-03-2018 CVS48_RS07530 93307e0a1a39232788e5f0d7b81177fc 422 SUPERFAMILY SSF56801 122 392 1.13E-32 T 29-03-2018 CVS48_RS10005 ac0fe7d7f9d5e313fb75c4545276d115 155 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 155 55.607 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS10005 ac0fe7d7f9d5e313fb75c4545276d115 155 Gene3D G3DSA:3.40.50.9100 7 153 4.1E-51 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS10005 ac0fe7d7f9d5e313fb75c4545276d115 155 PIRSF PIRSF001399 8 153 1.5E-49 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS10005 ac0fe7d7f9d5e313fb75c4545276d115 155 SUPERFAMILY SSF52304 8 150 1.7E-48 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS10005 ac0fe7d7f9d5e313fb75c4545276d115 155 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 12 144 1.0E-35 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS10005 ac0fe7d7f9d5e313fb75c4545276d115 155 Pfam PF01220 Dehydroquinase class II 12 147 3.5E-48 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS15110 ee7ffd998443bc81ece3505326f8c95d 451 SUPERFAMILY SSF102114 3 438 7.32E-131 T 29-03-2018 CVS48_RS15110 ee7ffd998443bc81ece3505326f8c95d 451 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 2 451 1.4E-167 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 CVS48_RS15110 ee7ffd998443bc81ece3505326f8c95d 451 Pfam PF04055 Radical SAM superfamily 50 221 1.1E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS15110 ee7ffd998443bc81ece3505326f8c95d 451 PIRSF PIRSF000167 2 448 5.4E-164 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 CVS48_RS15110 ee7ffd998443bc81ece3505326f8c95d 451 Gene3D G3DSA:3.20.20.70 27 346 1.4E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS15110 ee7ffd998443bc81ece3505326f8c95d 451 Pfam PF06969 HemN C-terminal domain 357 424 2.3E-8 T 29-03-2018 IPR010723 HemN, C-terminal CVS48_RS15110 ee7ffd998443bc81ece3505326f8c95d 451 SMART SM00729 45 263 3.0E-49 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CVS48_RS04555 165d1430b74ba6505fd72786d099b72f 718 Pfam PF13533 Biotin-lipoyl like 469 508 7.9E-6 T 29-03-2018 CVS48_RS04555 165d1430b74ba6505fd72786d099b72f 718 Pfam PF13437 HlyD family secretion protein 556 635 3.0E-9 T 29-03-2018 CVS48_RS04555 165d1430b74ba6505fd72786d099b72f 718 SUPERFAMILY SSF111369 452 612 6.28E-6 T 29-03-2018 CVS48_RS04555 165d1430b74ba6505fd72786d099b72f 718 Gene3D G3DSA:2.40.50.100 460 593 8.2E-12 T 29-03-2018 CVS48_RS00545 8531fbc851144c2e00dea6c3deae7bf9 109 SUPERFAMILY SSF46785 3 93 1.49E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00545 8531fbc851144c2e00dea6c3deae7bf9 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 3.6E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS00545 8531fbc851144c2e00dea6c3deae7bf9 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.6E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS00545 8531fbc851144c2e00dea6c3deae7bf9 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.6E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS00545 8531fbc851144c2e00dea6c3deae7bf9 109 Gene3D G3DSA:1.10.10.10 2 96 6.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00545 8531fbc851144c2e00dea6c3deae7bf9 109 SMART SM00418 9 89 3.1E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS00545 8531fbc851144c2e00dea6c3deae7bf9 109 Pfam PF12840 Helix-turn-helix domain 10 69 2.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06355 f0079d7deffd818956c964aecbd7c6e3 330 Pfam PF12697 Alpha/beta hydrolase family 77 311 1.6E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS06355 f0079d7deffd818956c964aecbd7c6e3 330 SUPERFAMILY SSF53474 56 314 1.99E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS06355 f0079d7deffd818956c964aecbd7c6e3 330 Gene3D G3DSA:3.40.50.1820 57 315 1.2E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS07190 844971c41fab447068f29ed0f65b79af 217 Gene3D G3DSA:3.40.50.1820 1 213 1.6E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS07190 844971c41fab447068f29ed0f65b79af 217 SUPERFAMILY SSF53474 5 209 1.33E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS00310 a56796d525a29c8af4776f5223b78205 206 PIRSF PIRSF001296 14 206 1.7E-76 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CVS48_RS00310 a56796d525a29c8af4776f5223b78205 206 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 15 202 35.304 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CVS48_RS00310 a56796d525a29c8af4776f5223b78205 206 Pfam PF02669 K+-transporting ATPase, c chain 19 201 8.5E-74 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CVS48_RS00310 a56796d525a29c8af4776f5223b78205 206 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 18 202 4.9E-74 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CVS48_RS11410 06854840a1cd63a8f671ae6b4c72fc6b 367 SUPERFAMILY SSF56601 46 345 3.27E-50 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS11410 06854840a1cd63a8f671ae6b4c72fc6b 367 Gene3D G3DSA:3.40.710.10 160 362 4.2E-28 T 29-03-2018 CVS48_RS11410 06854840a1cd63a8f671ae6b4c72fc6b 367 Gene3D G3DSA:3.40.710.10 36 159 2.8E-25 T 29-03-2018 CVS48_RS11410 06854840a1cd63a8f671ae6b4c72fc6b 367 Pfam PF00144 Beta-lactamase 51 346 6.4E-38 T 29-03-2018 IPR001466 Beta-lactamase-related CVS48_RS23365 3f4a72cbbe713dad85a6388466e63de7 318 Pfam PF00248 Aldo/keto reductase family 15 314 4.7E-70 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS23365 3f4a72cbbe713dad85a6388466e63de7 318 Gene3D G3DSA:3.20.20.100 1 317 4.8E-84 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS23365 3f4a72cbbe713dad85a6388466e63de7 318 SUPERFAMILY SSF51430 1 314 2.36E-91 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS16585 5106ec798789fca5adb302684f72ebd3 388 SUPERFAMILY SSF53822 29 372 1.07E-87 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS16585 5106ec798789fca5adb302684f72ebd3 388 Pfam PF13458 Periplasmic binding protein 29 367 7.9E-80 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS16585 5106ec798789fca5adb302684f72ebd3 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 279 292 3.8E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS16585 5106ec798789fca5adb302684f72ebd3 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 334 349 3.8E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS16585 5106ec798789fca5adb302684f72ebd3 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 68 3.8E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS16585 5106ec798789fca5adb302684f72ebd3 388 Gene3D G3DSA:3.40.50.2300 191 358 6.7E-20 T 29-03-2018 CVS48_RS16585 5106ec798789fca5adb302684f72ebd3 388 Gene3D G3DSA:3.40.50.2300 17 190 1.1E-30 T 29-03-2018 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 SUPERFAMILY SSF48150 6 226 6.28E-70 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 Pfam PF14815 NUDIX domain 238 345 1.9E-24 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 SMART SM00478 39 193 4.1E-43 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 Gene3D G3DSA:1.10.340.30 21 118 1.6E-32 T 29-03-2018 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 SUPERFAMILY SSF55811 223 347 1.42E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 Gene3D G3DSA:1.10.1670.10 119 228 4.8E-33 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 195 211 - T 29-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 6 269 5.7E-103 T 29-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 Gene3D G3DSA:3.90.79.10 234 356 5.7E-14 T 29-03-2018 CVS48_RS03615 254490675cd1d00518ed551427bf0b53 362 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 167 6.3E-20 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 24 212 3.7E-103 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 133 146 - T 29-03-2018 IPR033135 ClpP, histidine active site CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 SUPERFAMILY SSF52096 32 214 1.62E-73 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 Pfam PF00574 Clp protease 34 213 1.8E-87 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 24 214 44.409 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 PRINTS PR00127 Clp protease catalytic subunit P signature 189 208 2.0E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 PRINTS PR00127 Clp protease catalytic subunit P signature 40 55 2.0E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 PRINTS PR00127 Clp protease catalytic subunit P signature 132 151 2.0E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 PRINTS PR00127 Clp protease catalytic subunit P signature 80 100 2.0E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 PRINTS PR00127 Clp protease catalytic subunit P signature 111 128 2.0E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS21970 558f332ecb5c73c1f70a53b8fdea2d77 217 Gene3D G3DSA:3.90.226.10 23 215 1.5E-45 T 29-03-2018 CVS48_RS19375 7338e4faef705cb34facfeae5e7055e2 367 Gene3D G3DSA:3.10.560.10 234 341 3.0E-12 T 29-03-2018 CVS48_RS19375 7338e4faef705cb34facfeae5e7055e2 367 Gene3D G3DSA:3.10.560.10 157 233 2.2E-8 T 29-03-2018 CVS48_RS19375 7338e4faef705cb34facfeae5e7055e2 367 Gene3D G3DSA:3.30.1950.10 84 156 7.4E-15 T 29-03-2018 CVS48_RS19375 7338e4faef705cb34facfeae5e7055e2 367 Pfam PF10531 SLBB domain 171 221 7.1E-5 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS19375 7338e4faef705cb34facfeae5e7055e2 367 Pfam PF02563 Polysaccharide biosynthesis/export protein 77 162 6.0E-17 T 29-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 CVS48_RS24095 859923d2ac0780d63db94dad2ec958bc 329 Gene3D G3DSA:3.40.190.10 136 302 4.6E-13 T 29-03-2018 CVS48_RS24095 859923d2ac0780d63db94dad2ec958bc 329 SUPERFAMILY SSF53850 115 293 1.19E-16 T 29-03-2018 CVS48_RS24095 859923d2ac0780d63db94dad2ec958bc 329 PIRSF PIRSF017082 5 328 1.1E-90 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS24095 859923d2ac0780d63db94dad2ec958bc 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 324 2.7E-99 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04145 21144c46ea65f230d0efae6d13317fc3 356 Pfam PF00419 Fimbrial protein 215 355 2.5E-13 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CVS48_RS04145 21144c46ea65f230d0efae6d13317fc3 356 Gene3D G3DSA:2.60.40.1090 217 356 3.7E-22 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CVS48_RS04145 21144c46ea65f230d0efae6d13317fc3 356 SUPERFAMILY SSF49401 219 356 4.87E-19 T 29-03-2018 IPR008966 Adhesion domain CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 78 1.6E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 78 94 1.6E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 Pfam PF07729 FCD domain 130 254 6.4E-24 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 SUPERFAMILY SSF46785 37 108 5.18E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 SMART SM00895 128 255 4.1E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 Gene3D G3DSA:1.20.120.530 119 267 6.9E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 SMART SM00345 45 104 1.5E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 104 1.1E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 SUPERFAMILY SSF48008 125 262 5.23E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS16010 b1cfc5c2a92f0b858a12c3103ed894f6 267 Gene3D G3DSA:1.10.10.10 36 106 2.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16565 fb460d1246640982e89331bcadf5c645 171 Gene3D G3DSA:1.20.58.60 39 166 1.1E-5 T 29-03-2018 CVS48_RS16565 fb460d1246640982e89331bcadf5c645 171 SUPERFAMILY SSF46966 40 91 4.48E-5 T 29-03-2018 CVS48_RS04065 a490c29017e0a16f05637a133993d9f7 686 Gene3D G3DSA:3.40.50.300 281 381 1.7E-26 T 29-03-2018 CVS48_RS04065 a490c29017e0a16f05637a133993d9f7 686 Gene3D G3DSA:3.40.50.300 1 280 8.3E-51 T 29-03-2018 CVS48_RS04065 a490c29017e0a16f05637a133993d9f7 686 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 9 685 37.316 T 29-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 CVS48_RS04065 a490c29017e0a16f05637a133993d9f7 686 Gene3D G3DSA:1.10.486.10 382 561 2.9E-34 T 29-03-2018 CVS48_RS04065 a490c29017e0a16f05637a133993d9f7 686 Pfam PF13361 UvrD-like helicase C-terminal domain 511 635 1.4E-25 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CVS48_RS04065 a490c29017e0a16f05637a133993d9f7 686 Pfam PF13361 UvrD-like helicase C-terminal domain 276 426 1.6E-31 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CVS48_RS04065 a490c29017e0a16f05637a133993d9f7 686 SUPERFAMILY SSF52540 7 655 2.58E-148 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04065 a490c29017e0a16f05637a133993d9f7 686 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 270 3.8E-67 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CVS48_RS21255 6131ddbbc2bf1b8c957291be4e93657f 293 Pfam PF07859 alpha/beta hydrolase fold 66 154 5.1E-16 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CVS48_RS21255 6131ddbbc2bf1b8c957291be4e93657f 293 SUPERFAMILY SSF53474 36 284 7.9E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21255 6131ddbbc2bf1b8c957291be4e93657f 293 Gene3D G3DSA:3.40.50.1820 17 283 1.3E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS17355 cde8c0effb7de020c48c9be19a7846ac 258 Gene3D G3DSA:3.30.930.10 1 250 8.3E-57 T 29-03-2018 CVS48_RS17355 cde8c0effb7de020c48c9be19a7846ac 258 SUPERFAMILY SSF55681 4 254 2.4E-65 T 29-03-2018 CVS48_RS17355 cde8c0effb7de020c48c9be19a7846ac 258 Pfam PF03099 Biotin/lipoate A/B protein ligase family 64 172 1.6E-6 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CVS48_RS13805 3438e25a7a34b954338b2c35d93daa88 214 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 200 4.5E-61 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CVS48_RS13805 3438e25a7a34b954338b2c35d93daa88 214 Gene3D G3DSA:3.40.50.1240 1 212 2.2E-56 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CVS48_RS13805 3438e25a7a34b954338b2c35d93daa88 214 PIRSF PIRSF000709 1 118 1.6E-8 T 29-03-2018 CVS48_RS13805 3438e25a7a34b954338b2c35d93daa88 214 SUPERFAMILY SSF53254 1 206 1.31E-57 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CVS48_RS13805 3438e25a7a34b954338b2c35d93daa88 214 SMART SM00855 3 161 3.6E-21 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CVS48_RS03280 6a424989b06f2416da04a30e0150dd88 233 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 122 1.0E-16 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS03280 6a424989b06f2416da04a30e0150dd88 233 SUPERFAMILY SSF161098 17 213 4.32E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03280 6a424989b06f2416da04a30e0150dd88 233 Gene3D G3DSA:1.10.3720.10 2 231 4.5E-43 T 29-03-2018 CVS48_RS03280 6a424989b06f2416da04a30e0150dd88 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 228 9.6E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS02805 fd598fda123b1b70dacfd3f352a26d07 498 Gene3D G3DSA:3.40.190.10 202 304 5.2E-11 T 29-03-2018 CVS48_RS02805 fd598fda123b1b70dacfd3f352a26d07 498 Gene3D G3DSA:3.40.190.10 305 429 1.5E-21 T 29-03-2018 CVS48_RS02805 fd598fda123b1b70dacfd3f352a26d07 498 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 193 486 4.0E-56 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CVS48_RS02805 fd598fda123b1b70dacfd3f352a26d07 498 Pfam PF16868 NMT1-like family 209 486 1.1E-54 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CVS48_RS02805 fd598fda123b1b70dacfd3f352a26d07 498 SUPERFAMILY SSF53850 208 487 1.22E-54 T 29-03-2018 CVS48_RS28155 34610314849281b2eee0b4fb1beabe3b 447 Gene3D G3DSA:1.20.1250.20 30 239 9.2E-14 T 29-03-2018 CVS48_RS28155 34610314849281b2eee0b4fb1beabe3b 447 Pfam PF11700 Vacuole effluxer Atg22 like 166 441 1.3E-33 T 29-03-2018 IPR024671 Autophagy-related protein 22-like CVS48_RS28155 34610314849281b2eee0b4fb1beabe3b 447 Gene3D G3DSA:1.20.1250.20 243 439 6.0E-26 T 29-03-2018 CVS48_RS28155 34610314849281b2eee0b4fb1beabe3b 447 SUPERFAMILY SSF103473 36 434 3.53E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS09470 c798b7157a4763e1ae975849ac9a4be8 275 SMART SM00346 24 114 1.3E-23 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS09470 c798b7157a4763e1ae975849ac9a4be8 275 Gene3D G3DSA:1.10.10.10 24 87 2.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09470 c798b7157a4763e1ae975849ac9a4be8 275 Gene3D G3DSA:3.30.450.40 93 271 4.1E-45 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09470 c798b7157a4763e1ae975849ac9a4be8 275 Pfam PF01614 Bacterial transcriptional regulator 144 267 1.2E-28 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS09470 c798b7157a4763e1ae975849ac9a4be8 275 SUPERFAMILY SSF55781 95 267 8.5E-46 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09470 c798b7157a4763e1ae975849ac9a4be8 275 SUPERFAMILY SSF46785 24 97 1.07E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09470 c798b7157a4763e1ae975849ac9a4be8 275 Pfam PF09339 IclR helix-turn-helix domain 26 75 3.8E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS06800 bdc5193e4fa9acb0d72e93fb926e0e60 931 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 78 152 5.3E-25 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06800 bdc5193e4fa9acb0d72e93fb926e0e60 931 SMART SM00912 43 156 5.3E-37 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06800 bdc5193e4fa9acb0d72e93fb926e0e60 931 SUPERFAMILY SSF51126 67 337 1.35E-43 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS06800 bdc5193e4fa9acb0d72e93fb926e0e60 931 Gene3D G3DSA:2.160.20.10 38 316 1.1E-55 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS06800 bdc5193e4fa9acb0d72e93fb926e0e60 931 Gene3D G3DSA:2.160.20.10 317 386 1.5E-4 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS06800 bdc5193e4fa9acb0d72e93fb926e0e60 931 Pfam PF05860 haemagglutination activity domain 43 156 2.2E-24 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06800 bdc5193e4fa9acb0d72e93fb926e0e60 931 Pfam PF07581 The GLUG motif 654 675 0.0015 T 29-03-2018 IPR011493 GLUG CVS48_RS06800 bdc5193e4fa9acb0d72e93fb926e0e60 931 Pfam PF07581 The GLUG motif 794 818 3.1E-5 T 29-03-2018 IPR011493 GLUG CVS48_RS09200 7e9e44f583223a0c0dd11335c08ea659 214 SUPERFAMILY SSF100950 6 213 1.3E-66 T 29-03-2018 CVS48_RS09200 7e9e44f583223a0c0dd11335c08ea659 214 SMART SM00882 8 205 3.6E-68 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS09200 7e9e44f583223a0c0dd11335c08ea659 214 Pfam PF01144 Coenzyme A transferase 8 184 2.7E-37 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS09200 7e9e44f583223a0c0dd11335c08ea659 214 Gene3D G3DSA:3.40.1080.10 5 214 3.2E-59 T 29-03-2018 CVS48_RS09200 7e9e44f583223a0c0dd11335c08ea659 214 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 6 210 1.9E-90 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CVS48_RS26750 4595bef0dc1cc8cc74fe90876ed5c14a 256 SMART SM00382 34 228 2.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS26750 4595bef0dc1cc8cc74fe90876ed5c14a 256 Gene3D G3DSA:3.40.50.300 6 255 1.9E-49 T 29-03-2018 CVS48_RS26750 4595bef0dc1cc8cc74fe90876ed5c14a 256 Pfam PF00005 ABC transporter 26 181 2.9E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS26750 4595bef0dc1cc8cc74fe90876ed5c14a 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 250 1.4E-5 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS26750 4595bef0dc1cc8cc74fe90876ed5c14a 256 SUPERFAMILY SSF52540 9 250 6.29E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10475 1b9d0b267a893fcd884937da5813948e 132 SMART SM00530 13 69 2.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS10475 1b9d0b267a893fcd884937da5813948e 132 SUPERFAMILY SSF47413 9 74 2.46E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS10475 1b9d0b267a893fcd884937da5813948e 132 Pfam PF01381 Helix-turn-helix 14 69 4.0E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS10475 1b9d0b267a893fcd884937da5813948e 132 Gene3D G3DSA:1.10.260.40 6 73 1.1E-18 T 29-03-2018 CVS48_RS01410 ea143df1fcaf486ed0dca04beee7fe88 79 SUPERFAMILY SSF46689 9 77 2.4E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS01410 ea143df1fcaf486ed0dca04beee7fe88 79 Gene3D G3DSA:1.10.10.60 1 78 7.1E-18 T 29-03-2018 CVS48_RS01410 ea143df1fcaf486ed0dca04beee7fe88 79 PIRSF PIRSF002097 1 78 4.5E-26 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 CVS48_RS01410 ea143df1fcaf486ed0dca04beee7fe88 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 58 78 2.5E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS01410 ea143df1fcaf486ed0dca04beee7fe88 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 41 58 2.5E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS01410 ea143df1fcaf486ed0dca04beee7fe88 79 Pfam PF02954 Bacterial regulatory protein, Fis family 38 72 3.2E-15 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS17830 5272a0246e1d34676eb1d9bc7f265ba8 132 Pfam PF01042 Endoribonuclease L-PSP 13 127 4.4E-27 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS17830 5272a0246e1d34676eb1d9bc7f265ba8 132 Gene3D G3DSA:3.30.1330.40 1 131 9.6E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS17830 5272a0246e1d34676eb1d9bc7f265ba8 132 SUPERFAMILY SSF55298 8 129 7.85E-36 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS20125 b9a4d3df24455337ba94248d8a9ba45d 117 Pfam PF12840 Helix-turn-helix domain 22 95 4.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20125 b9a4d3df24455337ba94248d8a9ba45d 117 SMART SM00418 23 115 1.0E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS20125 b9a4d3df24455337ba94248d8a9ba45d 117 SUPERFAMILY SSF46785 19 114 1.51E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20125 b9a4d3df24455337ba94248d8a9ba45d 117 Gene3D G3DSA:1.10.10.10 3 113 6.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07700 a64048b872f82ca7c2248812b1b6bb11 160 Hamap MF_00048 UPF0102 protein YraN [yraN]. 43 158 20.751 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CVS48_RS07700 a64048b872f82ca7c2248812b1b6bb11 160 SUPERFAMILY SSF52980 43 128 6.7E-16 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CVS48_RS07700 a64048b872f82ca7c2248812b1b6bb11 160 Pfam PF02021 Uncharacterised protein family UPF0102 51 144 5.3E-24 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CVS48_RS07700 a64048b872f82ca7c2248812b1b6bb11 160 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 43 147 1.2E-24 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CVS48_RS07700 a64048b872f82ca7c2248812b1b6bb11 160 Gene3D G3DSA:3.40.1350.10 49 159 7.7E-30 T 29-03-2018 CVS48_RS17875 fed24ef0c055636a08c9516017700cb2 340 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 63 334 3.2E-68 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17875 fed24ef0c055636a08c9516017700cb2 340 PIRSF PIRSF017082 4 339 8.6E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17875 fed24ef0c055636a08c9516017700cb2 340 Gene3D G3DSA:3.40.190.10 139 277 8.1E-12 T 29-03-2018 CVS48_RS17875 fed24ef0c055636a08c9516017700cb2 340 SUPERFAMILY SSF53850 133 303 2.39E-11 T 29-03-2018 CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 SUPERFAMILY SSF46785 6 104 6.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 Pfam PF03466 LysR substrate binding domain 88 283 2.1E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.2E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 Gene3D G3DSA:3.40.190.10 174 261 5.2E-23 T 29-03-2018 CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 Gene3D G3DSA:3.40.190.10 87 173 3.0E-19 T 29-03-2018 CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 TIGRFAM TIGR03339 phn_lysR: aminoethylphosphonate catabolism associated LysR family transcriptional regulator 5 283 4.9E-127 T 29-03-2018 IPR017724 Aminoethylphosphonate utilisation-associated transcription regulator, LysR-type CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 Gene3D G3DSA:1.10.10.10 2 82 4.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27075 98ee2920afa85430888fab36633d96fb 287 SUPERFAMILY SSF53850 90 283 1.09E-37 T 29-03-2018 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 SUPERFAMILY SSF50985 148 369 2.62E-41 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Gene3D G3DSA:3.10.100.10 249 280 1.9E-11 T 29-03-2018 IPR016186 C-type lectin-like/link domain CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 150 178 4.9E-10 T 29-03-2018 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 432 475 7.4E-7 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 326 367 1.2E-7 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 271 319 7.7E-7 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 225 268 2.8E-6 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Gene3D G3DSA:2.130.10.30 281 366 1.1E-20 T 29-03-2018 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Gene3D G3DSA:4.10.510.10 146 207 4.8E-16 T 29-03-2018 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Gene3D G3DSA:4.10.510.10 208 248 1.3E-13 T 29-03-2018 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Gene3D G3DSA:4.10.510.10 367 414 7.9E-6 T 29-03-2018 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Gene3D G3DSA:4.10.510.10 463 507 3.7E-10 T 29-03-2018 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 Gene3D G3DSA:4.10.510.10 415 462 1.4E-11 T 29-03-2018 CVS48_RS21585 e927b634f131a63eb8e523a1b359bdf6 507 SUPERFAMILY SSF50985 322 505 5.23E-33 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CVS48_RS17015 6ac99b3769e75474f4350cb3c26ff3c0 100 Pfam PF01312 FlhB HrpN YscU SpaS Family 12 85 6.5E-17 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CVS48_RS17015 6ac99b3769e75474f4350cb3c26ff3c0 100 SUPERFAMILY SSF160544 12 89 4.71E-22 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CVS48_RS17015 6ac99b3769e75474f4350cb3c26ff3c0 100 Gene3D G3DSA:3.40.1690.10 11 89 2.1E-28 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CVS48_RS28670 33772672b3592728fb4a01c69b23a645 357 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 233 246 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28670 33772672b3592728fb4a01c69b23a645 357 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 21 352 24.786 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28670 33772672b3592728fb4a01c69b23a645 357 Pfam PF00146 NADH dehydrogenase 27 345 2.2E-125 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS01825 00d873715cf3521d92141385440c8bed 233 Gene3D G3DSA:1.10.8.60 170 226 6.2E-12 T 29-03-2018 CVS48_RS01825 00d873715cf3521d92141385440c8bed 233 Gene3D G3DSA:3.40.50.300 17 49 0.032 T 29-03-2018 CVS48_RS01825 00d873715cf3521d92141385440c8bed 233 Pfam PF00308 Bacterial dnaA protein 93 206 1.1E-7 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CVS48_RS01825 00d873715cf3521d92141385440c8bed 233 SMART SM00382 37 154 0.0064 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01825 00d873715cf3521d92141385440c8bed 233 Gene3D G3DSA:3.40.50.300 50 169 1.6E-5 T 29-03-2018 CVS48_RS01825 00d873715cf3521d92141385440c8bed 233 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 4 226 3.4E-67 T 29-03-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 CVS48_RS01825 00d873715cf3521d92141385440c8bed 233 SUPERFAMILY SSF52540 19 223 3.58E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06795 09986a6425c56540f6cd05b0d032513c 928 Gene3D G3DSA:2.160.20.10 289 357 1.2E-4 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS06795 09986a6425c56540f6cd05b0d032513c 928 Gene3D G3DSA:2.160.20.10 9 288 2.1E-56 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS06795 09986a6425c56540f6cd05b0d032513c 928 SUPERFAMILY SSF51126 13 308 2.98E-44 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS06795 09986a6425c56540f6cd05b0d032513c 928 Pfam PF07581 The GLUG motif 651 676 7.3E-5 T 29-03-2018 IPR011493 GLUG CVS48_RS06795 09986a6425c56540f6cd05b0d032513c 928 Pfam PF05860 haemagglutination activity domain 14 126 6.2E-25 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06795 09986a6425c56540f6cd05b0d032513c 928 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 49 123 3.8E-25 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06795 09986a6425c56540f6cd05b0d032513c 928 SMART SM00912 14 127 3.4E-38 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06105 a9a5224809c679b21913094a16b79f40 458 Gene3D G3DSA:1.10.3080.10 15 451 6.2E-85 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS06105 a9a5224809c679b21913094a16b79f40 458 Pfam PF00654 Voltage gated chloride channel 85 427 7.5E-85 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS06105 a9a5224809c679b21913094a16b79f40 458 PRINTS PR00762 Chloride channel signature 377 393 1.1E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS06105 a9a5224809c679b21913094a16b79f40 458 PRINTS PR00762 Chloride channel signature 341 361 1.1E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS06105 a9a5224809c679b21913094a16b79f40 458 PRINTS PR00762 Chloride channel signature 395 414 1.1E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS06105 a9a5224809c679b21913094a16b79f40 458 PRINTS PR00762 Chloride channel signature 178 197 1.1E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS06105 a9a5224809c679b21913094a16b79f40 458 PRINTS PR00762 Chloride channel signature 127 146 1.1E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS06105 a9a5224809c679b21913094a16b79f40 458 SUPERFAMILY SSF81340 16 441 1.83E-98 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS07515 2dbc0d3e8418c63a259c1d95cd8dfdf2 111 SMART SM00418 22 100 2.4E-24 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS07515 2dbc0d3e8418c63a259c1d95cd8dfdf2 111 SUPERFAMILY SSF46785 17 103 5.54E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07515 2dbc0d3e8418c63a259c1d95cd8dfdf2 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 4.1E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS07515 2dbc0d3e8418c63a259c1d95cd8dfdf2 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 4.1E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS07515 2dbc0d3e8418c63a259c1d95cd8dfdf2 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 4.1E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS07515 2dbc0d3e8418c63a259c1d95cd8dfdf2 111 Gene3D G3DSA:1.10.10.10 3 98 5.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07515 2dbc0d3e8418c63a259c1d95cd8dfdf2 111 Pfam PF01022 Bacterial regulatory protein, arsR family 30 74 4.4E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS27445 47fe562b3488c0f065adab2a50b8e94a 384 Gene3D G3DSA:1.10.8.350 139 248 9.6E-32 T 29-03-2018 CVS48_RS27445 47fe562b3488c0f065adab2a50b8e94a 384 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 77 377 2.9E-103 T 29-03-2018 IPR011757 Lytic transglycosylase MltB CVS48_RS27445 47fe562b3488c0f065adab2a50b8e94a 384 SUPERFAMILY SSF53955 63 379 7.31E-72 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS27445 47fe562b3488c0f065adab2a50b8e94a 384 Gene3D G3DSA:1.10.530.10 253 384 4.6E-24 T 29-03-2018 CVS48_RS27445 47fe562b3488c0f065adab2a50b8e94a 384 Pfam PF13406 Transglycosylase SLT domain 72 375 7.8E-80 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 CVS48_RS23375 3b9ffefe96f2185c48c6433e569001ff 513 Gene3D G3DSA:3.30.300.30 410 513 2.5E-29 T 29-03-2018 CVS48_RS23375 3b9ffefe96f2185c48c6433e569001ff 513 Pfam PF00501 AMP-binding enzyme 19 416 4.4E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS23375 3b9ffefe96f2185c48c6433e569001ff 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 500 3.3E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS23375 3b9ffefe96f2185c48c6433e569001ff 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS23375 3b9ffefe96f2185c48c6433e569001ff 513 Gene3D G3DSA:3.40.50.980 167 315 8.4E-46 T 29-03-2018 CVS48_RS23375 3b9ffefe96f2185c48c6433e569001ff 513 Gene3D G3DSA:2.30.38.10 316 409 3.5E-27 T 29-03-2018 CVS48_RS23375 3b9ffefe96f2185c48c6433e569001ff 513 Gene3D G3DSA:3.40.50.980 3 166 9.5E-36 T 29-03-2018 CVS48_RS23375 3b9ffefe96f2185c48c6433e569001ff 513 SUPERFAMILY SSF56801 6 512 4.97E-144 T 29-03-2018 CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 SUPERFAMILY SSF52096 486 792 7.69E-32 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 Gene3D G3DSA:3.90.226.10 481 794 4.7E-36 T 29-03-2018 CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 SUPERFAMILY SSF48179 344 458 1.02E-16 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 SUPERFAMILY SSF48179 192 311 3.4E-21 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 SUPERFAMILY SSF51735 5 192 9.28E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 Gene3D G3DSA:1.10.1040.10 192 299 4.2E-15 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 Pfam PF00378 Enoyl-CoA hydratase/isomerase 500 625 5.0E-12 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 Gene3D G3DSA:3.40.50.720 1 191 3.0E-47 T 29-03-2018 CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 194 293 3.1E-10 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 190 1.4E-45 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS23860 597d9f76173fdd7dc42db4a08b0ddfb1 796 Gene3D G3DSA:1.10.1040.10 353 437 2.3E-11 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS22035 ad6c716056f20531ad22fea2f85e8ef9 303 Pfam PF03466 LysR substrate binding domain 90 294 1.2E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS22035 ad6c716056f20531ad22fea2f85e8ef9 303 Gene3D G3DSA:3.40.190.10 88 175 6.1E-10 T 29-03-2018 CVS48_RS22035 ad6c716056f20531ad22fea2f85e8ef9 303 Gene3D G3DSA:3.40.190.10 176 265 3.6E-27 T 29-03-2018 CVS48_RS22035 ad6c716056f20531ad22fea2f85e8ef9 303 SUPERFAMILY SSF53850 91 299 2.17E-35 T 29-03-2018 CVS48_RS22035 ad6c716056f20531ad22fea2f85e8ef9 303 SUPERFAMILY SSF46785 2 111 6.95E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22035 ad6c716056f20531ad22fea2f85e8ef9 303 Gene3D G3DSA:1.10.10.10 1 84 1.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22035 ad6c716056f20531ad22fea2f85e8ef9 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 8.3E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04860 06e3c28e77c4f786ea4df6640f00fcda 341 Pfam PF13280 WYL domain 160 334 1.2E-30 T 29-03-2018 IPR026881 WYL domain CVS48_RS04860 06e3c28e77c4f786ea4df6640f00fcda 341 Gene3D G3DSA:1.10.10.10 2 71 7.5E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20110 c9c734cbc78d787703a1b12e0dfd72ff 124 Pfam PF01124 MAPEG family 4 121 1.5E-20 T 29-03-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein CVS48_RS20110 c9c734cbc78d787703a1b12e0dfd72ff 124 SUPERFAMILY SSF161084 4 120 1.1E-22 T 29-03-2018 CVS48_RS20110 c9c734cbc78d787703a1b12e0dfd72ff 124 Gene3D G3DSA:1.20.120.550 1 124 7.0E-18 T 29-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain CVS48_RS07650 21fe876d31a9ce35ce131b16a0a42f58 378 Pfam PF01098 Cell cycle protein 20 375 6.6E-102 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CVS48_RS07650 21fe876d31a9ce35ce131b16a0a42f58 378 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 332 356 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CVS48_RS07650 21fe876d31a9ce35ce131b16a0a42f58 378 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 16 374 3.4E-129 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 Pfam PF07729 FCD domain 100 221 3.8E-24 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 Gene3D G3DSA:1.10.10.10 13 86 2.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 SMART SM00895 100 222 2.2E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 SUPERFAMILY SSF46785 27 94 7.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 SMART SM00345 32 90 6.1E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 SUPERFAMILY SSF48008 99 229 9.68E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 90 4.8E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 64 6.2E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 80 6.2E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS04400 ea2f31eba40928207c304013734c3b95 238 Gene3D G3DSA:1.20.120.530 87 238 2.8E-32 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS07480 9b410a1c348d01eb28de650be1b43742 409 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 14 398 23.434 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CVS48_RS07480 9b410a1c348d01eb28de650be1b43742 409 Gene3D G3DSA:1.20.1530.10 12 397 9.8E-153 T 29-03-2018 IPR023171 Na/H antiporter domain CVS48_RS07480 9b410a1c348d01eb28de650be1b43742 409 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 17 392 5.5E-139 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CVS48_RS07480 9b410a1c348d01eb28de650be1b43742 409 Pfam PF06965 Na+/H+ antiporter 1 16 392 3.5E-149 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CVS48_RS03165 9922c31022b4e189b11a09b2bf5ff647 313 SUPERFAMILY SSF53613 3 298 1.87E-64 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS03165 9922c31022b4e189b11a09b2bf5ff647 313 Gene3D G3DSA:3.40.1190.20 3 309 2.2E-53 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS03165 9922c31022b4e189b11a09b2bf5ff647 313 Pfam PF00294 pfkB family carbohydrate kinase 36 294 2.8E-42 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CVS48_RS23380 45db2bd8d748631f043622590980bc18 263 Gene3D G3DSA:3.90.226.10 1 221 1.1E-53 T 29-03-2018 CVS48_RS23380 45db2bd8d748631f043622590980bc18 263 Gene3D G3DSA:1.10.12.10 222 263 8.4E-9 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS23380 45db2bd8d748631f043622590980bc18 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS23380 45db2bd8d748631f043622590980bc18 263 SUPERFAMILY SSF52096 8 262 5.64E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS23380 45db2bd8d748631f043622590980bc18 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 261 1.7E-40 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS02125 f444e8ef2526d8af1a6ad6b3c3a3bbab 205 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 14 176 1.2E-26 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN CVS48_RS02125 f444e8ef2526d8af1a6ad6b3c3a3bbab 205 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 23 173 3.1E-28 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN CVS48_RS22155 225d23d223dd4f9e741516ffb45d9a6c 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 63 329 5.9E-60 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22155 225d23d223dd4f9e741516ffb45d9a6c 337 Gene3D G3DSA:3.40.190.10 139 249 4.0E-9 T 29-03-2018 CVS48_RS22155 225d23d223dd4f9e741516ffb45d9a6c 337 PIRSF PIRSF017082 11 334 1.8E-65 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22155 225d23d223dd4f9e741516ffb45d9a6c 337 SUPERFAMILY SSF53850 123 299 6.51E-9 T 29-03-2018 CVS48_RS08450 61eeb628826d466c47d98f7965d1a0f5 351 Pfam PF00437 Type II/IV secretion system protein 18 303 2.9E-59 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS08450 61eeb628826d466c47d98f7965d1a0f5 351 SUPERFAMILY SSF52540 15 315 1.02E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08450 61eeb628826d466c47d98f7965d1a0f5 351 Gene3D G3DSA:3.40.50.300 113 338 8.3E-17 T 29-03-2018 CVS48_RS08450 61eeb628826d466c47d98f7965d1a0f5 351 Gene3D G3DSA:3.30.450.90 11 112 2.6E-21 T 29-03-2018 CVS48_RS18740 9fa8a05f7412f7bffc7c3d3e98ca94f0 131 Gene3D G3DSA:1.10.760.10 7 125 1.9E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18740 9fa8a05f7412f7bffc7c3d3e98ca94f0 131 SUPERFAMILY SSF46626 31 125 3.93E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18740 9fa8a05f7412f7bffc7c3d3e98ca94f0 131 Pfam PF00034 Cytochrome c 37 124 5.2E-5 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS25330 d00ddbd9bdf63a8254a654b6f8da34ce 500 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS25330 d00ddbd9bdf63a8254a654b6f8da34ce 500 Pfam PF00171 Aldehyde dehydrogenase family 22 479 2.5E-128 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS25330 d00ddbd9bdf63a8254a654b6f8da34ce 500 Gene3D G3DSA:3.40.605.10 12 271 5.3E-76 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS25330 d00ddbd9bdf63a8254a654b6f8da34ce 500 Gene3D G3DSA:3.40.309.10 272 468 3.7E-50 T 29-03-2018 CVS48_RS25330 d00ddbd9bdf63a8254a654b6f8da34ce 500 SUPERFAMILY SSF53720 18 487 5.89E-132 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS17770 6633895375ae134e9f18fea869240dac 328 Gene3D G3DSA:3.40.190.10 128 254 4.9E-10 T 29-03-2018 CVS48_RS17770 6633895375ae134e9f18fea869240dac 328 PIRSF PIRSF017082 1 327 1.8E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17770 6633895375ae134e9f18fea869240dac 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 325 2.4E-95 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17770 6633895375ae134e9f18fea869240dac 328 SUPERFAMILY SSF53850 114 288 1.9E-14 T 29-03-2018 CVS48_RS01590 5c182e58ed55aaea4ba7aacc7dab30cd 389 SUPERFAMILY SSF53901 22 118 1.53E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01590 5c182e58ed55aaea4ba7aacc7dab30cd 389 SUPERFAMILY SSF53901 181 354 1.53E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01590 5c182e58ed55aaea4ba7aacc7dab30cd 389 Gene3D G3DSA:3.40.47.10 8 235 6.6E-23 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01590 5c182e58ed55aaea4ba7aacc7dab30cd 389 Gene3D G3DSA:3.40.47.10 238 384 2.7E-5 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01590 5c182e58ed55aaea4ba7aacc7dab30cd 389 PIRSF PIRSF000429 14 371 1.5E-12 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS27960 239f4ae8b6ba5efb30c5ad0e4b3e1505 290 Pfam PF00149 Calcineurin-like phosphoesterase 21 218 8.1E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS27960 239f4ae8b6ba5efb30c5ad0e4b3e1505 290 SUPERFAMILY SSF56300 19 136 1.31E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS27960 239f4ae8b6ba5efb30c5ad0e4b3e1505 290 SUPERFAMILY SSF56300 192 256 1.31E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS27960 239f4ae8b6ba5efb30c5ad0e4b3e1505 290 Gene3D G3DSA:3.60.21.10 14 256 1.4E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS26790 db87a3e77157a5ab3c4bb4be6dd404db 397 Gene3D G3DSA:1.20.1170.10 136 203 0.2 T 29-03-2018 CVS48_RS26790 db87a3e77157a5ab3c4bb4be6dd404db 397 Gene3D G3DSA:1.20.1170.10 19 135 0.22 T 29-03-2018 CVS48_RS26790 db87a3e77157a5ab3c4bb4be6dd404db 397 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 39 386 3.4E-42 T 29-03-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 10 659 52.018 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 Gene3D G3DSA:3.40.50.980 81 273 1.4E-47 T 29-03-2018 CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 Pfam PF00501 AMP-binding enzyme 96 534 4.7E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 29 656 5.9E-298 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 Gene3D G3DSA:3.30.300.30 528 643 1.8E-27 T 29-03-2018 CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 Pfam PF13193 AMP-binding enzyme C-terminal domain 543 624 9.5E-28 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 ProSitePatterns PS00455 Putative AMP-binding domain signature. 268 279 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 SUPERFAMILY SSF56801 17 655 6.67E-173 T 29-03-2018 CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 33 88 3.0E-18 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 Gene3D G3DSA:2.30.38.10 440 527 6.7E-14 T 29-03-2018 CVS48_RS28150 02d3f1a1bb85393c6c294307a6be1ecc 659 Gene3D G3DSA:3.40.50.980 274 439 2.8E-38 T 29-03-2018 CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 Pfam PF03466 LysR substrate binding domain 87 290 4.9E-23 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 16 27 1.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 48 1.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 37 1.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 SUPERFAMILY SSF53850 83 290 5.25E-41 T 29-03-2018 CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 SUPERFAMILY SSF46785 1 78 4.84E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 Gene3D G3DSA:1.10.10.10 1 83 5.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 59 1.2E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 Gene3D G3DSA:3.40.190.10 84 202 3.6E-22 T 29-03-2018 CVS48_RS05900 627008ee5c8150e1ba91984ff6121f54 293 Gene3D G3DSA:3.40.190.10 215 293 1.6E-5 T 29-03-2018 CVS48_RS12815 2ac2b72f052cd8de5a1732ecc2757090 276 SUPERFAMILY SSF53927 29 275 1.8E-79 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CVS48_RS12815 2ac2b72f052cd8de5a1732ecc2757090 276 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 14 275 35.149 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CVS48_RS12815 2ac2b72f052cd8de5a1732ecc2757090 276 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 33 275 4.0E-70 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CVS48_RS12815 2ac2b72f052cd8de5a1732ecc2757090 276 Pfam PF02634 FdhD/NarQ family 36 274 7.0E-77 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CVS48_RS12815 2ac2b72f052cd8de5a1732ecc2757090 276 Gene3D G3DSA:3.40.140.10 139 276 1.3E-47 T 29-03-2018 CVS48_RS12815 2ac2b72f052cd8de5a1732ecc2757090 276 PIRSF PIRSF015626 8 276 2.0E-80 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CVS48_RS12815 2ac2b72f052cd8de5a1732ecc2757090 276 Gene3D G3DSA:3.10.20.10 38 125 5.0E-20 T 29-03-2018 CVS48_RS18090 6fcc043a87ccf8f59768201cd5fde4eb 327 PIRSF PIRSF017082 2 327 3.0E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS18090 6fcc043a87ccf8f59768201cd5fde4eb 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 321 1.1E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS18090 6fcc043a87ccf8f59768201cd5fde4eb 327 Gene3D G3DSA:3.40.190.10 128 235 5.1E-9 T 29-03-2018 CVS48_RS18090 6fcc043a87ccf8f59768201cd5fde4eb 327 SUPERFAMILY SSF53850 111 289 1.18E-14 T 29-03-2018 CVS48_RS15630 f60bc7f882a7b6227950ef3da5e181f6 322 Pfam PF00892 EamA-like transporter family 173 308 8.3E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS15630 f60bc7f882a7b6227950ef3da5e181f6 322 Pfam PF00892 EamA-like transporter family 27 155 6.4E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS15630 f60bc7f882a7b6227950ef3da5e181f6 322 SUPERFAMILY SSF103481 57 157 7.45E-12 T 29-03-2018 CVS48_RS15630 f60bc7f882a7b6227950ef3da5e181f6 322 SUPERFAMILY SSF103481 208 311 1.12E-11 T 29-03-2018 CVS48_RS16055 50dcc383fa73a974d37c2fef9cb5570d 170 SUPERFAMILY SSF88659 106 164 8.6E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16055 50dcc383fa73a974d37c2fef9cb5570d 170 Gene3D G3DSA:1.10.10.10 79 166 3.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16055 50dcc383fa73a974d37c2fef9cb5570d 170 SUPERFAMILY SSF88946 7 100 2.94E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16055 50dcc383fa73a974d37c2fef9cb5570d 170 Pfam PF04542 Sigma-70 region 2 15 79 1.0E-10 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16055 50dcc383fa73a974d37c2fef9cb5570d 170 Gene3D G3DSA:1.10.1740.10 2 78 6.6E-15 T 29-03-2018 CVS48_RS16055 50dcc383fa73a974d37c2fef9cb5570d 170 Pfam PF08281 Sigma-70, region 4 113 160 3.4E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16055 50dcc383fa73a974d37c2fef9cb5570d 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 161 4.6E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS02750 f2dffbb8a2d3f12ff511b395909ff473 306 SUPERFAMILY SSF103481 66 156 7.19E-10 T 29-03-2018 CVS48_RS02750 f2dffbb8a2d3f12ff511b395909ff473 306 Pfam PF00892 EamA-like transporter family 164 294 2.0E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS02750 f2dffbb8a2d3f12ff511b395909ff473 306 Pfam PF00892 EamA-like transporter family 23 147 2.1E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS02750 f2dffbb8a2d3f12ff511b395909ff473 306 SUPERFAMILY SSF103481 207 294 1.7E-6 T 29-03-2018 CVS48_RS14325 52727e0ffe88b414d921df2e4ccb05fa 156 PIRSF PIRSF004505 1 155 3.8E-43 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS14325 52727e0ffe88b414d921df2e4ccb05fa 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 26.858 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS14325 52727e0ffe88b414d921df2e4ccb05fa 156 SUPERFAMILY SSF75217 2 153 6.8E-46 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CVS48_RS14325 52727e0ffe88b414d921df2e4ccb05fa 156 Pfam PF02590 Predicted SPOUT methyltransferase 2 154 4.8E-47 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS14325 52727e0ffe88b414d921df2e4ccb05fa 156 Gene3D G3DSA:3.40.1280.10 1 155 9.1E-50 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 Pfam PF03466 LysR substrate binding domain 87 290 3.7E-23 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 SUPERFAMILY SSF53850 88 294 7.96E-27 T 29-03-2018 CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.0E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 Gene3D G3DSA:3.40.190.10 93 178 1.8E-14 T 29-03-2018 CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 Gene3D G3DSA:3.40.190.10 179 265 2.2E-9 T 29-03-2018 CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 SUPERFAMILY SSF46785 1 107 3.77E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08830 96aefe51a1d58add8e7ef9d84039ab7d 298 Gene3D G3DSA:1.10.10.10 1 92 3.8E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 Pfam PF02803 Thiolase, C-terminal domain 271 392 1.6E-45 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 Gene3D G3DSA:3.40.47.10 266 390 5.3E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 1.2E-138 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 SUPERFAMILY SSF53901 4 269 4.51E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 Pfam PF00108 Thiolase, N-terminal domain 4 262 7.6E-90 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 Gene3D G3DSA:3.40.47.10 1 160 2.8E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 Gene3D G3DSA:3.40.47.10 161 265 1.6E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 PIRSF PIRSF000429 1 393 1.4E-125 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 SUPERFAMILY SSF53901 271 392 4.99E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CVS48_RS23430 e4d364d146ced647127370fe5c8ced99 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CVS48_RS07755 9b4f2f547abaae6709d5ec25e037fd20 264 Gene3D G3DSA:3.40.50.300 10 262 7.0E-58 T 29-03-2018 CVS48_RS07755 9b4f2f547abaae6709d5ec25e037fd20 264 SUPERFAMILY SSF52540 22 260 2.83E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07755 9b4f2f547abaae6709d5ec25e037fd20 264 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 22 264 1.4E-114 T 29-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 CVS48_RS07755 9b4f2f547abaae6709d5ec25e037fd20 264 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS07755 9b4f2f547abaae6709d5ec25e037fd20 264 Pfam PF00005 ABC transporter 38 189 7.8E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07755 9b4f2f547abaae6709d5ec25e037fd20 264 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 237 259 4.9E-7 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS07755 9b4f2f547abaae6709d5ec25e037fd20 264 SMART SM00382 46 239 1.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05200 1d9a467d5d2689b118ef52b8383c27e3 151 SUPERFAMILY SSF101738 3 108 2.75E-43 T 29-03-2018 IPR007481 Stringent starvation protein B CVS48_RS05200 1d9a467d5d2689b118ef52b8383c27e3 151 PIRSF PIRSF005276 1 151 4.9E-50 T 29-03-2018 IPR007481 Stringent starvation protein B CVS48_RS05200 1d9a467d5d2689b118ef52b8383c27e3 151 Gene3D G3DSA:2.30.30.220 7 103 3.3E-35 T 29-03-2018 IPR007481 Stringent starvation protein B CVS48_RS05200 1d9a467d5d2689b118ef52b8383c27e3 151 Pfam PF04386 Stringent starvation protein B 5 151 5.1E-34 T 29-03-2018 IPR007481 Stringent starvation protein B CVS48_RS08275 41d18cf6d92582aa59c4e62bc686f16b 342 Pfam PF00535 Glycosyl transferase family 2 22 181 4.3E-33 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS08275 41d18cf6d92582aa59c4e62bc686f16b 342 SUPERFAMILY SSF53448 19 211 2.01E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS08275 41d18cf6d92582aa59c4e62bc686f16b 342 Gene3D G3DSA:3.90.550.10 4 232 1.0E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS23160 b6e0db8f3852b8b8b7b58ef9e1808db8 247 Gene3D G3DSA:1.10.760.10 42 216 4.6E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS23160 b6e0db8f3852b8b8b7b58ef9e1808db8 247 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 11 189 2.6E-80 T 29-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CVS48_RS23160 b6e0db8f3852b8b8b7b58ef9e1808db8 247 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 11 194 1.6E-78 T 29-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CVS48_RS23160 b6e0db8f3852b8b8b7b58ef9e1808db8 247 SUPERFAMILY SSF46626 21 202 2.66E-27 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS04260 6df700aa0b8e53479b2c65968f8c6fc9 509 Gene3D G3DSA:3.40.309.10 283 483 2.6E-65 T 29-03-2018 CVS48_RS04260 6df700aa0b8e53479b2c65968f8c6fc9 509 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 264 271 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS04260 6df700aa0b8e53479b2c65968f8c6fc9 509 Pfam PF00171 Aldehyde dehydrogenase family 30 496 2.7E-163 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS04260 6df700aa0b8e53479b2c65968f8c6fc9 509 Gene3D G3DSA:3.40.605.10 11 282 7.4E-95 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS04260 6df700aa0b8e53479b2c65968f8c6fc9 509 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 297 308 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS04260 6df700aa0b8e53479b2c65968f8c6fc9 509 SUPERFAMILY SSF53720 16 501 4.97E-161 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 Pfam PF00366 Ribosomal protein S17 18 84 8.4E-31 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 13 88 24.491 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 14 84 6.7E-35 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 Gene3D G3DSA:2.40.50.140 11 92 8.6E-29 T 29-03-2018 CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 SUPERFAMILY SSF50249 12 91 9.85E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 13 84 6.0E-36 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 PRINTS PR00973 Ribosomal protein S17 family signature 32 55 6.8E-10 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 PRINTS PR00973 Ribosomal protein S17 family signature 74 81 6.8E-10 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 PRINTS PR00973 Ribosomal protein S17 family signature 64 74 6.8E-10 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06430 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 ProSitePatterns PS00056 Ribosomal protein S17 signature. 64 76 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06135 03264cd9aaa459b8c7a173818470747d 388 Pfam PF00155 Aminotransferase class I and II 26 385 7.3E-58 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS06135 03264cd9aaa459b8c7a173818470747d 388 SUPERFAMILY SSF53383 3 387 4.92E-99 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS06135 03264cd9aaa459b8c7a173818470747d 388 Gene3D G3DSA:3.90.1150.10 297 388 2.4E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS06135 03264cd9aaa459b8c7a173818470747d 388 Gene3D G3DSA:3.40.640.10 40 296 9.5E-60 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS05990 4fda5520704121cb1496bfd4b75ee839 260 Gene3D G3DSA:1.10.3720.10 2 238 6.0E-42 T 29-03-2018 CVS48_RS05990 4fda5520704121cb1496bfd4b75ee839 260 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 131 1.8E-17 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS05990 4fda5520704121cb1496bfd4b75ee839 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 236 8.2E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05990 4fda5520704121cb1496bfd4b75ee839 260 SUPERFAMILY SSF161098 24 227 4.58E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS15460 519be82d53f4cef6ce972a6de986edbf 565 Pfam PF00501 AMP-binding enzyme 129 289 3.3E-10 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS15460 519be82d53f4cef6ce972a6de986edbf 565 Gene3D G3DSA:3.10.129.10 452 564 2.6E-17 T 29-03-2018 CVS48_RS15460 519be82d53f4cef6ce972a6de986edbf 565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 133 144 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS15460 519be82d53f4cef6ce972a6de986edbf 565 Gene3D G3DSA:3.40.50.980 13 137 1.4E-7 T 29-03-2018 CVS48_RS15460 519be82d53f4cef6ce972a6de986edbf 565 Gene3D G3DSA:3.40.50.980 138 292 2.3E-19 T 29-03-2018 CVS48_RS15460 519be82d53f4cef6ce972a6de986edbf 565 SUPERFAMILY SSF54637 457 556 2.98E-14 T 29-03-2018 IPR029069 HotDog domain CVS48_RS15460 519be82d53f4cef6ce972a6de986edbf 565 SUPERFAMILY SSF56801 30 434 2.49E-46 T 29-03-2018 CVS48_RS15460 519be82d53f4cef6ce972a6de986edbf 565 Gene3D G3DSA:3.30.300.30 337 444 3.1E-10 T 29-03-2018 CVS48_RS01335 ce73c892649943206f17116cddcd7567 229 Pfam PF03591 AzlC protein 13 157 1.8E-32 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease CVS48_RS11735 2ae51021a475b46a741e29a2cc231872 164 Gene3D G3DSA:3.30.300.20 69 164 4.2E-22 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS11735 2ae51021a475b46a741e29a2cc231872 164 SUPERFAMILY SSF82784 23 158 3.01E-32 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS11735 2ae51021a475b46a741e29a2cc231872 164 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 24 160 6.6E-37 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CVS48_RS11735 2ae51021a475b46a741e29a2cc231872 164 Pfam PF02566 OsmC-like protein 63 157 4.1E-18 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS11735 2ae51021a475b46a741e29a2cc231872 164 Gene3D G3DSA:2.20.25.10 21 68 2.8E-16 T 29-03-2018 CVS48_RS00990 da14ef3eb119495394a04d637302f52d 166 Pfam PF03713 Domain of unknown function (DUF305) 110 161 4.0E-11 T 29-03-2018 IPR005183 Domain of unknown function DUF305 CVS48_RS00990 da14ef3eb119495394a04d637302f52d 166 Gene3D G3DSA:1.20.1260.10 1 165 1.4E-21 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 6.7E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 SMART SM00421 155 212 3.7E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 Pfam PF00072 Response regulator receiver domain 5 115 3.7E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 SMART SM00448 2 116 2.2E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 SUPERFAMILY SSF46894 146 217 1.12E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 Gene3D G3DSA:3.40.50.2300 3 127 3.0E-22 T 29-03-2018 CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 SUPERFAMILY SSF52172 4 127 1.99E-22 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS13685 a0e3b53b3c9a56b5c79410e0eb4741d6 233 Gene3D G3DSA:1.10.10.10 128 221 1.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10185 2e1bac7779278273157579595f0b309e 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 4.6E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10185 2e1bac7779278273157579595f0b309e 302 SUPERFAMILY SSF53850 93 294 1.33E-30 T 29-03-2018 CVS48_RS10185 2e1bac7779278273157579595f0b309e 302 Gene3D G3DSA:3.40.190.10 94 178 2.6E-21 T 29-03-2018 CVS48_RS10185 2e1bac7779278273157579595f0b309e 302 Gene3D G3DSA:1.10.10.10 5 93 1.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10185 2e1bac7779278273157579595f0b309e 302 Gene3D G3DSA:3.40.190.10 179 264 1.7E-12 T 29-03-2018 CVS48_RS10185 2e1bac7779278273157579595f0b309e 302 SUPERFAMILY SSF46785 5 114 3.93E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10185 2e1bac7779278273157579595f0b309e 302 Pfam PF03466 LysR substrate binding domain 92 290 4.0E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 Pfam PF03466 LysR substrate binding domain 95 294 3.0E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 5.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 5.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 5.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 Gene3D G3DSA:3.40.190.10 179 265 1.8E-24 T 29-03-2018 CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 Gene3D G3DSA:3.40.190.10 97 178 7.3E-10 T 29-03-2018 CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 Gene3D G3DSA:1.10.10.10 9 90 8.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 SUPERFAMILY SSF53850 95 297 1.99E-36 T 29-03-2018 CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 69 3.5E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19525 38644a34739b7e856e6bbefd2a923086 298 SUPERFAMILY SSF46785 8 87 5.78E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16525 74fe2c1f710614bc73774401eec0746c 236 Pfam PF00005 ABC transporter 20 164 3.9E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS16525 74fe2c1f710614bc73774401eec0746c 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS16525 74fe2c1f710614bc73774401eec0746c 236 SMART SM00382 29 215 4.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16525 74fe2c1f710614bc73774401eec0746c 236 SUPERFAMILY SSF52540 4 233 1.25E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16525 74fe2c1f710614bc73774401eec0746c 236 Gene3D G3DSA:3.40.50.300 1 234 3.6E-50 T 29-03-2018 CVS48_RS19445 61e515d13ea58a5d4ca18cf6028e7f5d 560 SUPERFAMILY SSF161098 294 553 7.3E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19445 61e515d13ea58a5d4ca18cf6028e7f5d 560 Gene3D G3DSA:1.10.3720.10 58 283 3.2E-29 T 29-03-2018 CVS48_RS19445 61e515d13ea58a5d4ca18cf6028e7f5d 560 Gene3D G3DSA:1.10.3720.10 336 558 3.2E-27 T 29-03-2018 CVS48_RS19445 61e515d13ea58a5d4ca18cf6028e7f5d 560 SUPERFAMILY SSF161098 24 275 3.01E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19445 61e515d13ea58a5d4ca18cf6028e7f5d 560 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 385 549 3.4E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19445 61e515d13ea58a5d4ca18cf6028e7f5d 560 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 281 1.1E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20550 ff0c947a919aa0a7a99fde9199a34fd8 245 Pfam PF11445 Protein of unknown function (DUF2894) 23 221 4.1E-59 T 29-03-2018 IPR021549 Protein of unknown function DUF2894 CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 SUPERFAMILY SSF160467 2 84 3.4E-13 T 29-03-2018 CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 SMART SM00796 1 191 9.8E-98 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 SMART SM00797 269 552 2.2E-107 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 SUPERFAMILY SSF50891 426 539 4.55E-17 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 Gene3D G3DSA:2.40.100.10 78 208 1.4E-49 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 191 6.4E-68 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 271 536 2.1E-79 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 SUPERFAMILY SSF50891 80 202 6.07E-42 T 29-03-2018 IPR029000 Cyclophilin-like domain CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 Gene3D G3DSA:3.30.1360.40 1 76 1.1E-18 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CVS48_RS18475 a584646872eb7feec23de709054ba26d 554 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 247 539 2.4E-73 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CVS48_RS13300 029211422f37def381f39072f4ff9501 240 Gene3D G3DSA:3.40.1410.10 73 237 6.8E-30 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS13300 029211422f37def381f39072f4ff9501 240 Pfam PF07702 UTRA domain 96 231 1.1E-25 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS13300 029211422f37def381f39072f4ff9501 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 8.7E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13300 029211422f37def381f39072f4ff9501 240 SMART SM00345 14 73 2.8E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13300 029211422f37def381f39072f4ff9501 240 SUPERFAMILY SSF46785 1 81 1.04E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13300 029211422f37def381f39072f4ff9501 240 SMART SM00866 94 233 5.8E-25 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS13300 029211422f37def381f39072f4ff9501 240 Gene3D G3DSA:1.10.10.10 1 72 3.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13300 029211422f37def381f39072f4ff9501 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 9.2E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13300 029211422f37def381f39072f4ff9501 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 9.2E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS13300 029211422f37def381f39072f4ff9501 240 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 3 236 8.1E-73 T 29-03-2018 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF CVS48_RS13300 029211422f37def381f39072f4ff9501 240 SUPERFAMILY SSF64288 61 236 2.2E-34 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS10230 07c4acfc9dd8686c9db24c14c5029631 218 SMART SM00382 26 214 8.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS10230 07c4acfc9dd8686c9db24c14c5029631 218 SUPERFAMILY SSF52540 3 216 3.5E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10230 07c4acfc9dd8686c9db24c14c5029631 218 Pfam PF00005 ABC transporter 17 163 4.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS10230 07c4acfc9dd8686c9db24c14c5029631 218 Gene3D G3DSA:3.40.50.300 1 217 2.3E-49 T 29-03-2018 CVS48_RS00215 ab067f325206d87f5aec05bed0e1be00 313 Gene3D G3DSA:1.10.3720.10 2 301 7.2E-46 T 29-03-2018 CVS48_RS00215 ab067f325206d87f5aec05bed0e1be00 313 SUPERFAMILY SSF161098 96 298 6.87E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS00215 ab067f325206d87f5aec05bed0e1be00 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 313 8.1E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05540 ac9c0a0f7f291e9f397e050182dfb72b 204 SUPERFAMILY SSF52540 2 193 6.71E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05540 ac9c0a0f7f291e9f397e050182dfb72b 204 Pfam PF00005 ABC transporter 36 156 9.9E-14 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05540 ac9c0a0f7f291e9f397e050182dfb72b 204 Gene3D G3DSA:3.40.50.300 1 197 1.4E-37 T 29-03-2018 CVS48_RS28700 6d4e59443bb09c0b4a325d793c117bd3 158 Gene3D G3DSA:3.40.50.700 11 156 6.7E-48 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28700 6d4e59443bb09c0b4a325d793c117bd3 158 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 41.224 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28700 6d4e59443bb09c0b4a325d793c117bd3 158 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 2.8E-22 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28700 6d4e59443bb09c0b4a325d793c117bd3 158 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28700 6d4e59443bb09c0b4a325d793c117bd3 158 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 151 2.0E-75 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28700 6d4e59443bb09c0b4a325d793c117bd3 158 SUPERFAMILY SSF56770 9 151 1.31E-65 T 29-03-2018 CVS48_RS22210 c92cde0d84b6a1c64ccc6740f2ed7717 394 SUPERFAMILY SSF46626 72 197 3.56E-37 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS22210 c92cde0d84b6a1c64ccc6740f2ed7717 394 SUPERFAMILY SSF46626 232 394 8.48E-32 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS22210 c92cde0d84b6a1c64ccc6740f2ed7717 394 Gene3D G3DSA:1.10.760.10 251 394 2.8E-35 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS22210 c92cde0d84b6a1c64ccc6740f2ed7717 394 Gene3D G3DSA:1.10.760.10 71 250 1.5E-40 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS22210 c92cde0d84b6a1c64ccc6740f2ed7717 394 PIRSF PIRSF000294 49 220 2.4E-36 T 29-03-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 CVS48_RS22210 c92cde0d84b6a1c64ccc6740f2ed7717 394 PIRSF PIRSF000294 211 394 4.8E-35 T 29-03-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 CVS48_RS22210 c92cde0d84b6a1c64ccc6740f2ed7717 394 Pfam PF03150 Di-haem cytochrome c peroxidase 82 255 7.1E-41 T 29-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 CVS48_RS21895 2046dbd22b5b4ca23206ca59124571d8 296 SUPERFAMILY SSF52335 16 140 2.98E-19 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS21895 2046dbd22b5b4ca23206ca59124571d8 296 Gene3D G3DSA:3.40.50.1380 155 294 2.3E-22 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS21895 2046dbd22b5b4ca23206ca59124571d8 296 Gene3D G3DSA:3.40.50.1380 15 149 1.1E-12 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS21895 2046dbd22b5b4ca23206ca59124571d8 296 ProSitePatterns PS01335 Methylglyoxal synthase active site. 222 230 - T 29-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CVS48_RS21895 2046dbd22b5b4ca23206ca59124571d8 296 SUPERFAMILY SSF52335 155 290 8.7E-32 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CVS48_RS23340 df48d439a8bdf639dfc49e2be85f3142 560 Gene3D G3DSA:1.10.405.10 190 275 2.2E-26 T 29-03-2018 CVS48_RS23340 df48d439a8bdf639dfc49e2be85f3142 560 Gene3D G3DSA:3.40.50.720 10 189 4.2E-8 T 29-03-2018 CVS48_RS23340 df48d439a8bdf639dfc49e2be85f3142 560 SUPERFAMILY SSF51905 60 397 9.06E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23340 df48d439a8bdf639dfc49e2be85f3142 560 SUPERFAMILY SSF51905 504 539 9.06E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23340 df48d439a8bdf639dfc49e2be85f3142 560 Pfam PF13450 NAD(P)-binding Rossmann-like domain 63 131 1.7E-9 T 29-03-2018 CVS48_RS23825 a61e3643fe75d7d16e8d546c775bda37 250 Pfam PF00196 Bacterial regulatory proteins, luxR family 167 218 2.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23825 a61e3643fe75d7d16e8d546c775bda37 250 SUPERFAMILY SSF52172 2 128 1.48E-5 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS23825 a61e3643fe75d7d16e8d546c775bda37 250 SUPERFAMILY SSF46894 159 225 2.69E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS23825 a61e3643fe75d7d16e8d546c775bda37 250 SMART SM00421 164 221 5.8E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23825 a61e3643fe75d7d16e8d546c775bda37 250 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 4.5E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23825 a61e3643fe75d7d16e8d546c775bda37 250 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 4.5E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23825 a61e3643fe75d7d16e8d546c775bda37 250 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 4.5E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23825 a61e3643fe75d7d16e8d546c775bda37 250 Gene3D G3DSA:1.10.10.10 113 229 1.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07890 fc1215e17fb7d86a1c7bb29ee8a7673a 313 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 313 34.514 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CVS48_RS07890 fc1215e17fb7d86a1c7bb29ee8a7673a 313 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 309 1.1E-82 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CVS48_RS07890 fc1215e17fb7d86a1c7bb29ee8a7673a 313 Pfam PF02911 Formyl transferase, C-terminal domain 211 309 3.3E-20 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS07890 fc1215e17fb7d86a1c7bb29ee8a7673a 313 Gene3D G3DSA:3.40.50.170 1 213 2.7E-69 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS07890 fc1215e17fb7d86a1c7bb29ee8a7673a 313 SUPERFAMILY SSF53328 1 214 1.26E-65 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS07890 fc1215e17fb7d86a1c7bb29ee8a7673a 313 SUPERFAMILY SSF50486 212 311 1.22E-23 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CVS48_RS07890 fc1215e17fb7d86a1c7bb29ee8a7673a 313 Pfam PF00551 Formyl transferase 2 188 3.4E-43 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS07890 fc1215e17fb7d86a1c7bb29ee8a7673a 313 Gene3D G3DSA:3.10.25.10 214 312 2.6E-21 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 Gene3D G3DSA:3.90.226.10 14 290 3.6E-66 T 29-03-2018 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 283 37.822 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 1.6E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 1.6E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 1.6E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 1.6E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 1.6E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 285 1.1E-124 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 Pfam PF01039 Carboxyl transferase domain 100 242 8.2E-15 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CVS48_RS28390 b45d8db27bd14ba097cbe52d6dac8d61 291 SUPERFAMILY SSF52096 27 285 2.06E-83 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS17930 aeef70f44986d9c02e0bc5867126e7d9 382 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 378 3.0E-35 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS17930 aeef70f44986d9c02e0bc5867126e7d9 382 Gene3D G3DSA:3.30.70.270 206 382 9.2E-48 T 29-03-2018 CVS48_RS17930 aeef70f44986d9c02e0bc5867126e7d9 382 SUPERFAMILY SSF55073 226 380 9.42E-39 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS17930 aeef70f44986d9c02e0bc5867126e7d9 382 SMART SM00267 210 382 6.5E-43 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS17930 aeef70f44986d9c02e0bc5867126e7d9 382 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 381 2.3E-34 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS16735 9b568059d919714fa3b01c73f363f427 185 Gene3D G3DSA:2.60.120.10 1 184 5.0E-63 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS16735 9b568059d919714fa3b01c73f363f427 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 177 1.9E-58 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CVS48_RS16735 9b568059d919714fa3b01c73f363f427 185 SUPERFAMILY SSF51182 4 181 8.46E-64 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS16735 9b568059d919714fa3b01c73f363f427 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 177 2.9E-48 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CVS48_RS16735 9b568059d919714fa3b01c73f363f427 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 174 5.0E-64 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CVS48_RS00485 4e664a2e1f4ddf7d3d55df90414c401f 499 SUPERFAMILY SSF46689 6 75 9.32E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS00485 4e664a2e1f4ddf7d3d55df90414c401f 499 Gene3D G3DSA:1.10.10.10 31 79 1.6E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00485 4e664a2e1f4ddf7d3d55df90414c401f 499 Pfam PF00665 Integrase core domain 124 249 8.6E-13 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS00485 4e664a2e1f4ddf7d3d55df90414c401f 499 Gene3D G3DSA:3.30.420.10 128 304 4.3E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS00485 4e664a2e1f4ddf7d3d55df90414c401f 499 Gene3D G3DSA:1.10.10.60 4 30 4.2E-10 T 29-03-2018 CVS48_RS00485 4e664a2e1f4ddf7d3d55df90414c401f 499 Pfam PF13384 Homeodomain-like domain 12 37 8.5E-6 T 29-03-2018 CVS48_RS04085 1cca583fb16f9986911fa4ce7b289fc3 141 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 132 21.586 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04085 1cca583fb16f9986911fa4ce7b289fc3 141 SUPERFAMILY SSF51344 3 85 2.22E-25 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04085 1cca583fb16f9986911fa4ce7b289fc3 141 Gene3D G3DSA:1.20.5.440 90 128 1.9E-4 T 29-03-2018 CVS48_RS04085 1cca583fb16f9986911fa4ce7b289fc3 141 Gene3D G3DSA:2.60.15.10 1 89 9.9E-31 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04085 1cca583fb16f9986911fa4ce7b289fc3 141 SUPERFAMILY SSF46604 87 135 1.05E-7 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04085 1cca583fb16f9986911fa4ce7b289fc3 141 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 85 9.0E-36 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04085 1cca583fb16f9986911fa4ce7b289fc3 141 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 6.5E-30 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS04085 1cca583fb16f9986911fa4ce7b289fc3 141 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 127 8.8E-41 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS11515 b47e314f334aec4ce1d3b0c240f5c353 443 Pfam PF02913 FAD linked oxidases, C-terminal domain 204 440 9.2E-43 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS11515 b47e314f334aec4ce1d3b0c240f5c353 443 SUPERFAMILY SSF55103 174 442 8.18E-49 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS11515 b47e314f334aec4ce1d3b0c240f5c353 443 Gene3D G3DSA:3.30.43.10 5 76 2.1E-19 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS11515 b47e314f334aec4ce1d3b0c240f5c353 443 Gene3D G3DSA:3.30.465.10 77 220 4.8E-41 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS11515 b47e314f334aec4ce1d3b0c240f5c353 443 SUPERFAMILY SSF56176 10 200 2.84E-67 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS11515 b47e314f334aec4ce1d3b0c240f5c353 443 Pfam PF01565 FAD binding domain 24 161 8.0E-39 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS11515 b47e314f334aec4ce1d3b0c240f5c353 443 Gene3D G3DSA:1.10.45.10 402 441 1.3E-12 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CVS48_RS10275 2e84573fbbd0b821657cc5ee0fec941a 197 Pfam PF14124 Domain of unknown function (DUF4291) 14 192 9.5E-70 T 29-03-2018 IPR025633 Protein of unknown function DUF4291 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 Pfam PF00072 Response regulator receiver domain 5 111 1.1E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 Pfam PF02954 Bacterial regulatory protein, Fis family 398 439 3.3E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 SMART SM00382 156 322 3.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 348 357 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 SMART SM00448 2 111 2.8E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 Gene3D G3DSA:3.40.50.300 131 307 7.5E-28 T 29-03-2018 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 4.3E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 4.3E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 Gene3D G3DSA:1.10.10.60 396 440 9.4E-14 T 29-03-2018 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 Gene3D G3DSA:1.10.8.60 308 384 3.5E-23 T 29-03-2018 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 Gene3D G3DSA:3.40.50.2300 1 121 1.2E-28 T 29-03-2018 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 SUPERFAMILY SSF46689 348 439 2.58E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 SUPERFAMILY SSF52540 136 377 2.01E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 SUPERFAMILY SSF52172 1 181 9.68E-36 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS19070 66a7bef3412d094396b420cfd5660604 460 Pfam PF00158 Sigma-54 interaction domain 137 303 2.0E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CVS48_RS18155 26d020b5a6288ac8c20ca2736cbf2ad5 319 Pfam PF12833 Helix-turn-helix domain 238 316 1.8E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS18155 26d020b5a6288ac8c20ca2736cbf2ad5 319 Gene3D G3DSA:1.10.10.60 274 318 2.1E-14 T 29-03-2018 CVS48_RS18155 26d020b5a6288ac8c20ca2736cbf2ad5 319 SUPERFAMILY SSF46689 219 266 1.17E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS18155 26d020b5a6288ac8c20ca2736cbf2ad5 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS18155 26d020b5a6288ac8c20ca2736cbf2ad5 319 SMART SM00342 232 315 1.7E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS18155 26d020b5a6288ac8c20ca2736cbf2ad5 319 SUPERFAMILY SSF46689 269 316 2.82E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS18155 26d020b5a6288ac8c20ca2736cbf2ad5 319 Gene3D G3DSA:1.10.357.10 95 228 0.006 T 29-03-2018 CVS48_RS18155 26d020b5a6288ac8c20ca2736cbf2ad5 319 Gene3D G3DSA:1.10.10.60 229 273 1.7E-16 T 29-03-2018 CVS48_RS01735 4a34ac7b1be811e542362de028192299 369 Gene3D G3DSA:3.50.50.60 311 369 2.7E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01735 4a34ac7b1be811e542362de028192299 369 Gene3D G3DSA:3.50.50.60 3 55 5.3E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01735 4a34ac7b1be811e542362de028192299 369 Gene3D G3DSA:3.30.9.10 87 195 3.1E-19 T 29-03-2018 CVS48_RS01735 4a34ac7b1be811e542362de028192299 369 Gene3D G3DSA:3.30.9.10 202 310 5.2E-28 T 29-03-2018 CVS48_RS01735 4a34ac7b1be811e542362de028192299 369 SUPERFAMILY SSF51905 5 223 5.61E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01735 4a34ac7b1be811e542362de028192299 369 SUPERFAMILY SSF51905 327 361 5.61E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01735 4a34ac7b1be811e542362de028192299 369 Pfam PF01266 FAD dependent oxidoreductase 6 363 4.2E-64 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS15660 0c86ca36d5f900cf795d279a4ee5a9f9 540 Gene3D G3DSA:3.30.300.30 436 538 4.8E-30 T 29-03-2018 CVS48_RS15660 0c86ca36d5f900cf795d279a4ee5a9f9 540 Pfam PF00501 AMP-binding enzyme 37 440 4.9E-88 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS15660 0c86ca36d5f900cf795d279a4ee5a9f9 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS15660 0c86ca36d5f900cf795d279a4ee5a9f9 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 528 1.6E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS15660 0c86ca36d5f900cf795d279a4ee5a9f9 540 Gene3D G3DSA:3.40.50.980 27 195 1.5E-40 T 29-03-2018 CVS48_RS15660 0c86ca36d5f900cf795d279a4ee5a9f9 540 Gene3D G3DSA:3.40.50.980 196 349 1.8E-34 T 29-03-2018 CVS48_RS15660 0c86ca36d5f900cf795d279a4ee5a9f9 540 Gene3D G3DSA:2.30.38.10 350 434 3.1E-19 T 29-03-2018 CVS48_RS15660 0c86ca36d5f900cf795d279a4ee5a9f9 540 SUPERFAMILY SSF56801 8 536 1.19E-142 T 29-03-2018 CVS48_RS27695 54aaf6ca45b384a3382bc14be303c11f 262 Pfam PF13525 Outer membrane lipoprotein 30 235 1.2E-60 T 29-03-2018 CVS48_RS27695 54aaf6ca45b384a3382bc14be303c11f 262 Gene3D G3DSA:1.25.20.10 27 255 4.0E-19 T 29-03-2018 CVS48_RS27695 54aaf6ca45b384a3382bc14be303c11f 262 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 241 37.912 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD CVS48_RS27695 54aaf6ca45b384a3382bc14be303c11f 262 SUPERFAMILY SSF48452 30 108 8.23E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS27695 54aaf6ca45b384a3382bc14be303c11f 262 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 2 246 5.0E-85 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD CVS48_RS18195 0d72df261fe5f6fea13270fc16290e0e 1134 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 276 1132 0.0 T 29-03-2018 IPR018667 Domain of unknown function DUF2126 CVS48_RS18195 0d72df261fe5f6fea13270fc16290e0e 1134 Gene3D G3DSA:3.90.260.10 165 287 6.2E-5 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS18195 0d72df261fe5f6fea13270fc16290e0e 1134 SUPERFAMILY SSF54001 9 337 1.82E-67 T 29-03-2018 CVS48_RS18195 0d72df261fe5f6fea13270fc16290e0e 1134 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 84 1.0E-26 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CVS48_RS18195 0d72df261fe5f6fea13270fc16290e0e 1134 Pfam PF01841 Transglutaminase-like superfamily 137 246 2.9E-17 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS18195 0d72df261fe5f6fea13270fc16290e0e 1134 SMART SM00460 172 248 7.1E-19 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 294 1.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 SUPERFAMILY SSF47384 213 294 6.08E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 Gene3D G3DSA:3.30.565.10 302 449 3.7E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 SUPERFAMILY SSF55874 285 432 1.83E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 2.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 427 2.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 Pfam PF08521 Two-component sensor kinase N-terminal 17 150 3.8E-10 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 447 2.8E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 Gene3D G3DSA:1.10.287.130 220 291 3.8E-13 T 29-03-2018 CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 SMART SM00387 344 446 5.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 SMART SM00388 230 295 4.2E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 Gene3D G3DSA:1.20.5.1040 1 63 3.6E-9 T 29-03-2018 CVS48_RS16295 63d0100496ff4a5e4e81b8706a2d3e74 452 Gene3D G3DSA:1.20.5.1040 125 177 5.8E-10 T 29-03-2018 CVS48_RS06125 07b70dc42878c62518939688de5f5a9e 145 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 6 137 7.6E-21 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 CVS48_RS15170 635e63cad56eba2744ed39ffb9ac1de2 65 SUPERFAMILY SSF143034 2 64 1.29E-23 T 29-03-2018 CVS48_RS15170 635e63cad56eba2744ed39ffb9ac1de2 65 Pfam PF01632 Ribosomal protein L35 2 62 2.6E-25 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15170 635e63cad56eba2744ed39ffb9ac1de2 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 4.2E-27 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CVS48_RS15170 635e63cad56eba2744ed39ffb9ac1de2 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS15170 635e63cad56eba2744ed39ffb9ac1de2 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.4E-18 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CVS48_RS15170 635e63cad56eba2744ed39ffb9ac1de2 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.4E-18 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CVS48_RS15170 635e63cad56eba2744ed39ffb9ac1de2 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.4E-18 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CVS48_RS15170 635e63cad56eba2744ed39ffb9ac1de2 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.916 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CVS48_RS10035 c0364a5cfa4d64861c914962d7d2c0ce 223 SUPERFAMILY SSF56235 1 222 3.24E-70 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS10035 c0364a5cfa4d64861c914962d7d2c0ce 223 Gene3D G3DSA:3.60.20.10 1 215 7.8E-70 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS10035 c0364a5cfa4d64861c914962d7d2c0ce 223 Pfam PF06267 Family of unknown function (DUF1028) 2 190 1.7E-60 T 29-03-2018 IPR010430 Protein of unknown function DUF1028 CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 PIRSF PIRSF004692 1 329 1.3E-127 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 SMART SM00116 215 263 0.021 T 29-03-2018 IPR000644 CBS domain CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 SMART SM00116 280 328 18.0 T 29-03-2018 IPR000644 CBS domain CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 Pfam PF00571 CBS domain 277 326 5.0E-5 T 29-03-2018 IPR000644 CBS domain CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 Pfam PF00571 CBS domain 206 263 8.7E-6 T 29-03-2018 IPR000644 CBS domain CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 SUPERFAMILY SSF53697 16 327 4.0E-65 T 29-03-2018 CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 50 319 8.8E-102 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 Gene3D G3DSA:3.40.50.10490 6 204 1.7E-53 T 29-03-2018 CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 Pfam PF01380 SIS domain 45 177 5.8E-30 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CVS48_RS07775 7226ba3714888a9a9c931b4007026539 329 Gene3D G3DSA:3.10.580.10 205 327 9.2E-22 T 29-03-2018 CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 SMART SM00345 9 68 2.3E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 4.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 4.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 Pfam PF07702 UTRA domain 100 230 1.3E-16 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 SUPERFAMILY SSF64288 56 236 5.02E-31 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 Gene3D G3DSA:1.10.10.10 2 70 9.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 SUPERFAMILY SSF46785 3 72 1.58E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 Gene3D G3DSA:3.40.1410.10 72 240 1.3E-32 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 1.5E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS11820 ad9dacb96ae576e09eec559805240ef5 240 SMART SM00866 89 231 8.5E-16 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CVS48_RS23185 f2085e8ab62c042a4295df32cc309fae 395 Gene3D G3DSA:3.90.1150.10 290 395 7.1E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS23185 f2085e8ab62c042a4295df32cc309fae 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 245 254 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CVS48_RS23185 f2085e8ab62c042a4295df32cc309fae 395 SUPERFAMILY SSF53383 6 394 7.43E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS23185 f2085e8ab62c042a4295df32cc309fae 395 Gene3D G3DSA:3.40.640.10 49 289 5.4E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS23185 f2085e8ab62c042a4295df32cc309fae 395 Pfam PF00155 Aminotransferase class I and II 41 389 2.6E-54 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS12330 ab8965556235653b6c7dce3e7b3c5e09 180 SUPERFAMILY SSF55729 22 177 2.95E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS12330 ab8965556235653b6c7dce3e7b3c5e09 180 Gene3D G3DSA:3.40.630.30 5 180 3.0E-31 T 29-03-2018 CVS48_RS12330 ab8965556235653b6c7dce3e7b3c5e09 180 Pfam PF13673 Acetyltransferase (GNAT) domain 63 156 8.4E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS03080 600cedd0d5bdc365a8cce2075117a038 230 SUPERFAMILY SSF52499 23 220 1.11E-52 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS03080 600cedd0d5bdc365a8cce2075117a038 230 Pfam PF00857 Isochorismatase family 29 214 1.1E-36 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS03080 600cedd0d5bdc365a8cce2075117a038 230 Gene3D G3DSA:3.40.50.850 18 230 1.3E-48 T 29-03-2018 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 SMART SM00028 378 411 0.0011 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 SUPERFAMILY SSF48452 352 438 6.0E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 PRINTS PR00996 Glutamate methyltransferase family signature 222 245 1.4E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 PRINTS PR00996 Glutamate methyltransferase family signature 203 217 1.4E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 1.4E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 PRINTS PR00996 Glutamate methyltransferase family signature 134 150 1.4E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 PRINTS PR00996 Glutamate methyltransferase family signature 101 121 1.4E-19 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 Pfam PF01739 CheR methyltransferase, SAM binding domain 96 244 1.3E-34 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 Gene3D G3DSA:1.10.155.10 2 64 3.2E-6 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 Gene3D G3DSA:1.25.40.10 391 443 1.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 SMART SM00138 1 263 2.0E-35 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 Gene3D G3DSA:3.40.50.150 66 258 1.0E-37 T 29-03-2018 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 SUPERFAMILY SSF53335 67 253 5.46E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 Gene3D G3DSA:1.25.40.10 347 390 3.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS20685 10eb6d754a84b05db7aed0f308b6da7f 446 Pfam PF13181 Tetratricopeptide repeat 378 411 8.2E-6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS01915 6fa72c4d1125dd8361b0c39105391ca0 299 SUPERFAMILY SSF46785 2 112 2.49E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01915 6fa72c4d1125dd8361b0c39105391ca0 299 Gene3D G3DSA:1.10.10.10 1 85 1.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01915 6fa72c4d1125dd8361b0c39105391ca0 299 Gene3D G3DSA:3.40.190.10 90 176 9.9E-22 T 29-03-2018 CVS48_RS01915 6fa72c4d1125dd8361b0c39105391ca0 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.7E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01915 6fa72c4d1125dd8361b0c39105391ca0 299 Gene3D G3DSA:3.40.190.10 177 266 1.6E-17 T 29-03-2018 CVS48_RS01915 6fa72c4d1125dd8361b0c39105391ca0 299 Pfam PF03466 LysR substrate binding domain 89 296 1.5E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS01915 6fa72c4d1125dd8361b0c39105391ca0 299 SUPERFAMILY SSF53850 90 297 2.82E-40 T 29-03-2018 CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 9.2E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 SUPERFAMILY SSF46785 1 86 4.59E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 Gene3D G3DSA:3.40.190.10 177 274 1.5E-29 T 29-03-2018 CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 SUPERFAMILY SSF53850 88 298 2.9E-43 T 29-03-2018 CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 Pfam PF03466 LysR substrate binding domain 87 296 3.7E-49 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 Gene3D G3DSA:1.10.10.10 1 82 4.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19400 bc7503df38d39aed03b59642fd069353 316 Gene3D G3DSA:3.40.190.10 88 176 1.5E-22 T 29-03-2018 CVS48_RS01065 c6ded45400b38a9e8832a76a9fe5c764 547 Pfam PF00437 Type II/IV secretion system protein 194 456 3.9E-73 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS01065 c6ded45400b38a9e8832a76a9fe5c764 547 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 384 398 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS01065 c6ded45400b38a9e8832a76a9fe5c764 547 Gene3D G3DSA:3.30.450.90 154 287 1.7E-40 T 29-03-2018 CVS48_RS01065 c6ded45400b38a9e8832a76a9fe5c764 547 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 46 149 3.2E-9 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 CVS48_RS01065 c6ded45400b38a9e8832a76a9fe5c764 547 SUPERFAMILY SSF52540 177 543 8.08E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01065 c6ded45400b38a9e8832a76a9fe5c764 547 Gene3D G3DSA:3.40.50.300 290 547 2.0E-46 T 29-03-2018 CVS48_RS01065 c6ded45400b38a9e8832a76a9fe5c764 547 SUPERFAMILY SSF160246 23 140 1.83E-5 T 29-03-2018 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 SMART SM00919 163 400 3.2E-134 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 SUPERFAMILY SSF53223 11 161 1.29E-50 T 29-03-2018 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 Pfam PF03949 Malic enzyme, NAD binding domain 165 360 2.3E-20 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 Gene3D G3DSA:3.40.50.720 161 450 1.2E-81 T 29-03-2018 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 Gene3D G3DSA:3.40.718.10 451 750 4.5E-53 T 29-03-2018 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 SMART SM01274 18 151 4.1E-76 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 SUPERFAMILY SSF51735 163 438 1.97E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 Pfam PF01515 Phosphate acetyl/butaryl transferase 429 755 2.6E-96 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 Gene3D G3DSA:3.40.50.10380 5 160 2.7E-34 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 SUPERFAMILY SSF53659 429 758 1.97E-87 T 29-03-2018 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 PIRSF PIRSF036684 1 762 0.0 T 29-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 CVS48_RS13105 8087e01227a67fc3d3162b3566697190 762 Pfam PF00390 Malic enzyme, N-terminal domain 19 151 1.1E-25 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CVS48_RS11380 5663d43281e5a938aba8c9cd75c87cf9 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 325 3.5E-65 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11380 5663d43281e5a938aba8c9cd75c87cf9 330 SUPERFAMILY SSF53850 117 290 4.65E-11 T 29-03-2018 CVS48_RS11380 5663d43281e5a938aba8c9cd75c87cf9 330 Gene3D G3DSA:3.40.190.10 129 239 5.2E-8 T 29-03-2018 CVS48_RS11380 5663d43281e5a938aba8c9cd75c87cf9 330 PIRSF PIRSF017082 3 328 3.1E-67 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09465 0b754e0f9e8cc33635ee00ceb5cd7131 260 SUPERFAMILY SSF51197 2 253 3.71E-59 T 29-03-2018 CVS48_RS09465 0b754e0f9e8cc33635ee00ceb5cd7131 260 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 14 224 2.8E-32 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CVS48_RS09465 0b754e0f9e8cc33635ee00ceb5cd7131 260 Gene3D G3DSA:2.60.120.620 2 246 1.5E-46 T 29-03-2018 CVS48_RS20045 2ae0e41579e38821e6809bbd27b2eab7 199 SMART SM00471 24 161 6.7E-8 T 29-03-2018 IPR003607 HD/PDEase domain CVS48_RS20045 2ae0e41579e38821e6809bbd27b2eab7 199 SUPERFAMILY SSF109604 20 192 5.14E-33 T 29-03-2018 CVS48_RS20045 2ae0e41579e38821e6809bbd27b2eab7 199 Gene3D G3DSA:1.10.3210.10 13 196 3.6E-42 T 29-03-2018 CVS48_RS20045 2ae0e41579e38821e6809bbd27b2eab7 199 Pfam PF01966 HD domain 30 151 2.5E-18 T 29-03-2018 IPR006674 HD domain CVS48_RS20045 2ae0e41579e38821e6809bbd27b2eab7 199 TIGRFAM TIGR00277 HDIG: HDIG domain 27 119 8.9E-8 T 29-03-2018 IPR006675 HDIG domain CVS48_RS04625 9a21e72d4937344c54813dc6f29db47d 330 PIRSF PIRSF017082 1 330 1.2E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04625 9a21e72d4937344c54813dc6f29db47d 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 326 1.3E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04625 9a21e72d4937344c54813dc6f29db47d 330 SUPERFAMILY SSF53850 111 293 2.04E-11 T 29-03-2018 CVS48_RS04625 9a21e72d4937344c54813dc6f29db47d 330 Gene3D G3DSA:3.40.190.10 38 299 2.2E-8 T 29-03-2018 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 SUPERFAMILY SSF46894 141 210 2.79E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 Gene3D G3DSA:3.40.50.2300 1 126 9.2E-39 T 29-03-2018 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 5.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 5.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 5.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 SMART SM00448 2 115 1.1E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 3.8E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 Gene3D G3DSA:1.10.10.10 127 213 1.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 SUPERFAMILY SSF52172 3 131 3.27E-36 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 Pfam PF00072 Response regulator receiver domain 5 116 2.7E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS18580 705718ab29bb5b8c302dab40502140ed 217 SMART SM00421 146 203 1.4E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS28740 35f60fd50d8e3f7c8390327d078d01ed 330 SUPERFAMILY SSF111331 26 328 1.46E-53 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CVS48_RS28740 35f60fd50d8e3f7c8390327d078d01ed 330 SMART SM00046 26 155 0.0019 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CVS48_RS28740 35f60fd50d8e3f7c8390327d078d01ed 330 Gene3D G3DSA:3.40.50.10330 18 155 1.5E-24 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CVS48_RS28740 35f60fd50d8e3f7c8390327d078d01ed 330 Pfam PF00781 Diacylglycerol kinase catalytic domain 27 150 3.0E-23 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CVS48_RS03385 ee2b9eb79ecc79b73f2d91f97b1a3d34 414 Pfam PF01738 Dienelactone hydrolase family 20 233 3.1E-45 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CVS48_RS03385 ee2b9eb79ecc79b73f2d91f97b1a3d34 414 SUPERFAMILY SSF54427 245 384 1.75E-23 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS03385 ee2b9eb79ecc79b73f2d91f97b1a3d34 414 Gene3D G3DSA:3.10.450.50 245 381 2.4E-20 T 29-03-2018 CVS48_RS03385 ee2b9eb79ecc79b73f2d91f97b1a3d34 414 SUPERFAMILY SSF53474 6 233 5.26E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03385 ee2b9eb79ecc79b73f2d91f97b1a3d34 414 Gene3D G3DSA:3.40.50.1820 5 238 8.9E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS20065 65367d806ac35900c34f076bf979d4d3 322 Pfam PF13437 HlyD family secretion protein 204 314 3.0E-16 T 29-03-2018 CVS48_RS20065 65367d806ac35900c34f076bf979d4d3 322 Pfam PF13533 Biotin-lipoyl like 42 88 6.0E-6 T 29-03-2018 CVS48_RS20065 65367d806ac35900c34f076bf979d4d3 322 Gene3D G3DSA:2.40.50.100 40 102 4.9E-9 T 29-03-2018 CVS48_RS20065 65367d806ac35900c34f076bf979d4d3 322 Gene3D G3DSA:1.20.1600.10 174 269 2.2E-7 T 29-03-2018 CVS48_RS20065 65367d806ac35900c34f076bf979d4d3 322 SUPERFAMILY SSF111369 150 273 7.72E-8 T 29-03-2018 CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 Pfam PF03466 LysR substrate binding domain 85 284 2.7E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 Gene3D G3DSA:3.40.190.10 82 185 9.7E-17 T 29-03-2018 CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 60 1.0E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 Gene3D G3DSA:3.40.190.10 186 257 1.4E-10 T 29-03-2018 CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 SUPERFAMILY SSF53850 87 287 8.38E-29 T 29-03-2018 CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 Gene3D G3DSA:1.10.10.10 1 81 3.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11550 aaab6b0094358c78def90a8965731539 293 SUPERFAMILY SSF46785 2 78 1.38E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06750 80fbe9a6f00796d39a4db41d30484160 109 Pfam PF01491 Frataxin-like domain 1 103 2.0E-21 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS06750 80fbe9a6f00796d39a4db41d30484160 109 ProSitePatterns PS01344 Frataxin family signature. 52 66 - T 29-03-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS06750 80fbe9a6f00796d39a4db41d30484160 109 SMART SM01219 1 108 8.5E-38 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS06750 80fbe9a6f00796d39a4db41d30484160 109 Hamap MF_00142 Protein CyaY [cyaY]. 1 107 23.689 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS06750 80fbe9a6f00796d39a4db41d30484160 109 SUPERFAMILY SSF55387 1 107 3.31E-29 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS06750 80fbe9a6f00796d39a4db41d30484160 109 Gene3D G3DSA:3.30.920.10 1 109 2.2E-25 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS06750 80fbe9a6f00796d39a4db41d30484160 109 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 106 6.8E-34 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 7.2E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 7.2E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 7.2E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 Gene3D G3DSA:3.30.70.920 58 156 4.4E-27 T 29-03-2018 CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 Gene3D G3DSA:1.10.10.10 1 56 1.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 SUPERFAMILY SSF46785 4 96 2.33E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 SMART SM00344 6 115 7.6E-42 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 8.1E-20 T 29-03-2018 CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 SUPERFAMILY SSF54909 66 155 2.28E-21 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CVS48_RS15260 74b511bd4e731594e874ccdfdc5ccd76 156 Pfam PF01037 Lrp/AsnC ligand binding domain 72 146 4.0E-25 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS10800 ecf5cf827ccdfce8d6c45f3fda240833 432 Pfam PF04209 homogentisate 1,2-dioxygenase 4 427 1.4E-203 T 29-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CVS48_RS10800 ecf5cf827ccdfce8d6c45f3fda240833 432 SUPERFAMILY SSF51182 2 430 2.73E-175 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS10800 ecf5cf827ccdfce8d6c45f3fda240833 432 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 2 427 4.1E-202 T 29-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CVS48_RS10800 ecf5cf827ccdfce8d6c45f3fda240833 432 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 4 429 71.081 T 29-03-2018 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 CVS48_RS10800 ecf5cf827ccdfce8d6c45f3fda240833 432 Gene3D G3DSA:2.60.120.10 274 397 4.8E-53 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS10800 ecf5cf827ccdfce8d6c45f3fda240833 432 Gene3D G3DSA:2.60.120.10 195 236 2.2E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS02715 a26f2caa78fd0123fd5a78f28d60aab1 265 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS02715 a26f2caa78fd0123fd5a78f28d60aab1 265 Pfam PF00005 ABC transporter 29 169 4.5E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS02715 a26f2caa78fd0123fd5a78f28d60aab1 265 SUPERFAMILY SSF52540 5 239 6.51E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02715 a26f2caa78fd0123fd5a78f28d60aab1 265 Gene3D G3DSA:3.40.50.300 4 251 2.3E-53 T 29-03-2018 CVS48_RS02715 a26f2caa78fd0123fd5a78f28d60aab1 265 SMART SM00382 32 221 4.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS18745 d89fd70531242a52df6de7e20b446b21 317 Gene3D G3DSA:1.10.760.10 50 163 3.0E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18745 d89fd70531242a52df6de7e20b446b21 317 SUPERFAMILY SSF46626 223 314 4.14E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18745 d89fd70531242a52df6de7e20b446b21 317 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 75 155 3.2E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18745 d89fd70531242a52df6de7e20b446b21 317 SUPERFAMILY SSF46626 77 167 9.74E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18745 d89fd70531242a52df6de7e20b446b21 317 Gene3D G3DSA:1.10.760.10 166 314 4.7E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18745 d89fd70531242a52df6de7e20b446b21 317 Pfam PF00034 Cytochrome c 226 313 4.7E-7 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS27280 3ec2e5c740d331ab9e94604220377be3 262 Gene3D G3DSA:3.90.226.10 5 220 1.1E-60 T 29-03-2018 CVS48_RS27280 3ec2e5c740d331ab9e94604220377be3 262 SUPERFAMILY SSF52096 1 261 1.13E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS27280 3ec2e5c740d331ab9e94604220377be3 262 Gene3D G3DSA:1.10.12.10 221 262 1.7E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS27280 3ec2e5c740d331ab9e94604220377be3 262 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 7 262 7.0E-135 T 29-03-2018 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 CVS48_RS27280 3ec2e5c740d331ab9e94604220377be3 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 262 6.6E-61 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS10525 68b66bad9f9199a50e2acb26184536d7 631 Gene3D G3DSA:3.10.20.310 193 269 8.7E-6 T 29-03-2018 CVS48_RS10525 68b66bad9f9199a50e2acb26184536d7 631 Pfam PF17243 POTRA domain TamA domain 1 32 94 1.3E-6 T 29-03-2018 IPR035243 TamA, POTRA domain 1 CVS48_RS10525 68b66bad9f9199a50e2acb26184536d7 631 Pfam PF01103 Surface antigen 443 631 1.3E-21 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 CVS48_RS10525 68b66bad9f9199a50e2acb26184536d7 631 Gene3D G3DSA:3.10.20.310 106 192 1.3E-11 T 29-03-2018 CVS48_RS10525 68b66bad9f9199a50e2acb26184536d7 631 Gene3D G3DSA:2.40.160.50 286 631 2.4E-40 T 29-03-2018 CVS48_RS22590 36030fba8b581544e39c9c07e6d31d72 488 SUPERFAMILY SSF53720 3 480 2.62E-164 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS22590 36030fba8b581544e39c9c07e6d31d72 488 Gene3D G3DSA:3.40.605.10 1 259 3.2E-94 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS22590 36030fba8b581544e39c9c07e6d31d72 488 Gene3D G3DSA:3.40.309.10 260 460 8.6E-74 T 29-03-2018 CVS48_RS22590 36030fba8b581544e39c9c07e6d31d72 488 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 3 487 5.1E-221 T 29-03-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 CVS48_RS22590 36030fba8b581544e39c9c07e6d31d72 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 271 282 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS22590 36030fba8b581544e39c9c07e6d31d72 488 Pfam PF00171 Aldehyde dehydrogenase family 16 474 3.1E-170 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS22590 36030fba8b581544e39c9c07e6d31d72 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 243 250 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS13470 10045b39e5501f26d43087d40afb911a 262 SMART SM00062 34 258 2.2E-47 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS13470 10045b39e5501f26d43087d40afb911a 262 SUPERFAMILY SSF53850 3 257 1.99E-59 T 29-03-2018 CVS48_RS13470 10045b39e5501f26d43087d40afb911a 262 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 255 1.1E-52 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS13470 10045b39e5501f26d43087d40afb911a 262 Gene3D G3DSA:3.40.190.10 177 255 1.5E-11 T 29-03-2018 CVS48_RS13470 10045b39e5501f26d43087d40afb911a 262 Gene3D G3DSA:3.40.190.10 23 176 1.1E-32 T 29-03-2018 CVS48_RS25010 717d63fc35fdb9a19b50ec65b52cea74 324 SUPERFAMILY SSF54593 6 282 3.7E-38 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS25010 717d63fc35fdb9a19b50ec65b52cea74 324 Gene3D G3DSA:3.10.180.10 2 140 7.0E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS25010 717d63fc35fdb9a19b50ec65b52cea74 324 Gene3D G3DSA:3.10.180.10 146 296 4.2E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS25010 717d63fc35fdb9a19b50ec65b52cea74 324 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 155 268 1.3E-16 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS27645 8de877d89ed35c68b779fe42ad592bf9 290 Gene3D G3DSA:3.10.310.10 1 126 2.8E-24 T 29-03-2018 CVS48_RS27645 8de877d89ed35c68b779fe42ad592bf9 290 SUPERFAMILY SSF54506 4 289 3.49E-65 T 29-03-2018 CVS48_RS27645 8de877d89ed35c68b779fe42ad592bf9 290 Gene3D G3DSA:3.10.310.10 127 279 9.1E-34 T 29-03-2018 CVS48_RS27645 8de877d89ed35c68b779fe42ad592bf9 290 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 288 2.7E-50 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CVS48_RS27645 8de877d89ed35c68b779fe42ad592bf9 290 PIRSF PIRSF016184 1 290 5.6E-65 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CVS48_RS27645 8de877d89ed35c68b779fe42ad592bf9 290 Pfam PF02567 Phenazine biosynthesis-like protein 10 281 6.0E-48 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CVS48_RS26470 225ddfb622a7edfa5e7d8dd29a0c0a1d 300 SUPERFAMILY SSF103481 44 145 3.14E-13 T 29-03-2018 CVS48_RS26470 225ddfb622a7edfa5e7d8dd29a0c0a1d 300 SUPERFAMILY SSF103481 196 294 1.14E-13 T 29-03-2018 CVS48_RS26470 225ddfb622a7edfa5e7d8dd29a0c0a1d 300 Pfam PF00892 EamA-like transporter family 18 143 6.6E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS26470 225ddfb622a7edfa5e7d8dd29a0c0a1d 300 Pfam PF00892 EamA-like transporter family 155 289 2.3E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS14455 5e310e9360a027a5f8c42c86afe050c9 1227 Pfam PF13116 Protein of unknown function 412 693 1.7E-41 T 29-03-2018 IPR025263 Domain of unknown function DUF3971 CVS48_RS14455 5e310e9360a027a5f8c42c86afe050c9 1227 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 227 1192 2.5E-221 T 29-03-2018 IPR011836 Conserved hypothetical protein CHP02099 CVS48_RS14455 5e310e9360a027a5f8c42c86afe050c9 1227 Pfam PF13502 AsmA-like C-terminal region 945 1182 1.4E-50 T 29-03-2018 IPR032712 AsmA-like, C-terminal CVS48_RS19315 3d1ddc411dc0099f2ce92a20cd7913d3 283 Gene3D G3DSA:1.10.3720.10 2 272 3.3E-32 T 29-03-2018 CVS48_RS19315 3d1ddc411dc0099f2ce92a20cd7913d3 283 SUPERFAMILY SSF161098 4 279 1.12E-58 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19315 3d1ddc411dc0099f2ce92a20cd7913d3 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 278 4.1E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS02580 5cc322c0a23c7be5a7ea6366199989e9 111 PRINTS PR00606 Class ID cytochrome C signature 29 42 9.1E-14 T 29-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CVS48_RS02580 5cc322c0a23c7be5a7ea6366199989e9 111 PRINTS PR00606 Class ID cytochrome C signature 68 81 9.1E-14 T 29-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CVS48_RS02580 5cc322c0a23c7be5a7ea6366199989e9 111 PRINTS PR00606 Class ID cytochrome C signature 83 93 9.1E-14 T 29-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CVS48_RS02580 5cc322c0a23c7be5a7ea6366199989e9 111 PRINTS PR00606 Class ID cytochrome C signature 95 105 9.1E-14 T 29-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CVS48_RS02580 5cc322c0a23c7be5a7ea6366199989e9 111 Gene3D G3DSA:1.10.760.10 24 107 6.2E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS02580 5cc322c0a23c7be5a7ea6366199989e9 111 SUPERFAMILY SSF46626 9 108 3.15E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS02580 5cc322c0a23c7be5a7ea6366199989e9 111 Pfam PF00034 Cytochrome c 26 106 4.6E-7 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS11565 c02bcca8d41006ee7622ca28aa25b49a 305 SUPERFAMILY SSF63829 42 298 1.07E-61 T 29-03-2018 CVS48_RS11565 c02bcca8d41006ee7622ca28aa25b49a 305 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 45 283 1.6E-44 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CVS48_RS11565 c02bcca8d41006ee7622ca28aa25b49a 305 Gene3D G3DSA:2.120.10.30 89 297 6.1E-33 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS11565 c02bcca8d41006ee7622ca28aa25b49a 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 162 184 1.7E-9 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CVS48_RS11565 c02bcca8d41006ee7622ca28aa25b49a 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 266 284 1.7E-9 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CVS48_RS11565 c02bcca8d41006ee7622ca28aa25b49a 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 223 240 1.7E-9 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CVS48_RS11565 c02bcca8d41006ee7622ca28aa25b49a 305 Gene3D G3DSA:2.120.10.30 12 88 2.6E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS15300 a5c30fb759d4f97ff3e7356b00b759be 330 PIRSF PIRSF017082 1 330 4.5E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS15300 a5c30fb759d4f97ff3e7356b00b759be 330 SUPERFAMILY SSF53850 116 292 1.85E-12 T 29-03-2018 CVS48_RS15300 a5c30fb759d4f97ff3e7356b00b759be 330 Gene3D G3DSA:3.40.190.10 130 239 4.1E-10 T 29-03-2018 CVS48_RS15300 a5c30fb759d4f97ff3e7356b00b759be 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 326 1.6E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13445 3d3fde11080656f60220343bebe720cb 226 Gene3D G3DSA:3.40.1080.10 2 225 1.8E-79 T 29-03-2018 CVS48_RS13445 3d3fde11080656f60220343bebe720cb 226 Pfam PF01144 Coenzyme A transferase 7 218 3.3E-62 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS13445 3d3fde11080656f60220343bebe720cb 226 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 221 3.8E-109 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CVS48_RS13445 3d3fde11080656f60220343bebe720cb 226 SMART SM00882 6 219 1.5E-74 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS13445 3d3fde11080656f60220343bebe720cb 226 SUPERFAMILY SSF100950 2 220 2.99E-75 T 29-03-2018 CVS48_RS28200 55bf147d3bcc9397d03d2c6774c10a17 369 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 3 355 4.8E-100 T 29-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 CVS48_RS28200 55bf147d3bcc9397d03d2c6774c10a17 369 Pfam PF03739 Predicted permease YjgP/YjgQ family 8 356 1.6E-52 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 Gene3D G3DSA:3.30.450.20 372 497 8.2E-13 T 29-03-2018 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 SUPERFAMILY SSF55785 375 484 1.84E-6 T 29-03-2018 IPR000014 PAS domain CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 Pfam PF01627 Hpt domain 1037 1118 1.1E-5 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 SUPERFAMILY SSF55874 560 733 6.29E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 Gene3D G3DSA:3.40.50.2300 857 990 1.1E-36 T 29-03-2018 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 SMART SM00388 506 571 6.0E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 SMART SM00448 860 971 6.2E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 Pfam PF00072 Response regulator receiver domain 862 970 1.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 SUPERFAMILY SSF52172 860 984 5.98E-35 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 Pfam PF00512 His Kinase A (phospho-acceptor) domain 506 571 2.2E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 Gene3D G3DSA:1.10.287.130 498 567 2.2E-15 T 29-03-2018 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 Gene3D G3DSA:3.30.565.10 575 737 9.9E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 Gene3D G3DSA:1.20.120.160 1026 1121 1.8E-7 T 29-03-2018 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 673 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 693 711 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 677 687 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 717 730 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 SMART SM00387 618 733 1.6E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 SUPERFAMILY SSF47384 491 572 1.06E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 618 731 1.2E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 SUPERFAMILY SSF47226 954 967 8.54E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS12035 8cf30f627a9ebbc9c748d642b9a2c8bf 1121 SUPERFAMILY SSF47226 1016 1116 8.54E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CVS48_RS15130 92bacf44f272824ba1ff3c97ea83ab06 323 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 127 300 3.0E-74 T 29-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CVS48_RS15130 92bacf44f272824ba1ff3c97ea83ab06 323 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 1 123 2.3E-37 T 29-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CVS48_RS15130 92bacf44f272824ba1ff3c97ea83ab06 323 Hamap MF_00162 Glutathione synthetase [gshB]. 1 319 154.286 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CVS48_RS15130 92bacf44f272824ba1ff3c97ea83ab06 323 SUPERFAMILY SSF56059 127 314 1.1E-57 T 29-03-2018 CVS48_RS15130 92bacf44f272824ba1ff3c97ea83ab06 323 SUPERFAMILY SSF52440 1 125 1.35E-33 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS15130 92bacf44f272824ba1ff3c97ea83ab06 323 Gene3D G3DSA:3.30.470.20 194 303 3.0E-16 T 29-03-2018 CVS48_RS15130 92bacf44f272824ba1ff3c97ea83ab06 323 TIGRFAM TIGR01380 glut_syn: glutathione synthase 1 315 5.7E-122 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CVS48_RS15130 92bacf44f272824ba1ff3c97ea83ab06 323 Gene3D G3DSA:3.40.50.20 1 132 1.3E-42 T 29-03-2018 CVS48_RS15130 92bacf44f272824ba1ff3c97ea83ab06 323 Gene3D G3DSA:3.30.1490.20 141 193 1.3E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS21115 db34623bde1b3a82c61bd152e3b85ee4 289 Gene3D G3DSA:3.90.850.10 20 289 1.4E-72 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS21115 db34623bde1b3a82c61bd152e3b85ee4 289 SUPERFAMILY SSF56529 62 284 9.81E-74 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS21115 db34623bde1b3a82c61bd152e3b85ee4 289 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 283 1.0E-59 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS21115 db34623bde1b3a82c61bd152e3b85ee4 289 Pfam PF10370 Domain of unknown function (DUF2437) 1 69 2.0E-5 T 29-03-2018 IPR018833 Domain of unknown function DUF2437 CVS48_RS25310 6f6a74680d3a8347ee170d6db4e1b975 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 112 3.7E-25 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS25310 6f6a74680d3a8347ee170d6db4e1b975 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 220 5.4E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS25310 6f6a74680d3a8347ee170d6db4e1b975 229 Gene3D G3DSA:1.10.3720.10 2 222 4.5E-39 T 29-03-2018 CVS48_RS25310 6f6a74680d3a8347ee170d6db4e1b975 229 SUPERFAMILY SSF161098 14 205 8.24E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS17815 2da054b7a6bb0e20191bcd03df5283f9 443 Gene3D G3DSA:3.30.1120.10 348 431 2.9E-13 T 29-03-2018 CVS48_RS17815 2da054b7a6bb0e20191bcd03df5283f9 443 SUPERFAMILY SSF53649 2 431 1.45E-113 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS17815 2da054b7a6bb0e20191bcd03df5283f9 443 Pfam PF00884 Sulfatase 5 326 2.4E-63 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CVS48_RS17815 2da054b7a6bb0e20191bcd03df5283f9 443 Pfam PF14707 C-terminal region of aryl-sulfatase 351 433 3.3E-8 T 29-03-2018 CVS48_RS17815 2da054b7a6bb0e20191bcd03df5283f9 443 Gene3D G3DSA:3.40.720.10 5 347 1.6E-78 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS07930 1fcf086419c55d5d09020d6b68bf6c25 210 Pfam PF01810 LysE type translocator 15 204 3.8E-30 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS07930 1fcf086419c55d5d09020d6b68bf6c25 210 PIRSF PIRSF006324 1 207 6.5E-53 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS11050 34d3400454e9802ed8f7481f5960ada8 185 Gene3D G3DSA:3.90.950.20 13 185 2.0E-55 T 29-03-2018 CVS48_RS11050 34d3400454e9802ed8f7481f5960ada8 185 Pfam PF02464 Competence-damaged protein 24 180 1.2E-53 T 29-03-2018 IPR008136 CinA, C-terminal CVS48_RS11050 34d3400454e9802ed8f7481f5960ada8 185 SUPERFAMILY SSF142433 21 181 7.19E-52 T 29-03-2018 IPR008136 CinA, C-terminal CVS48_RS11050 34d3400454e9802ed8f7481f5960ada8 185 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 30 178 1.1E-40 T 29-03-2018 IPR008136 CinA, C-terminal CVS48_RS02705 38ee0a21853c249734605b3b9fd9a5fa 228 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 7 227 17.664 T 29-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 CVS48_RS02705 38ee0a21853c249734605b3b9fd9a5fa 228 Gene3D G3DSA:1.25.40.10 108 228 9.3E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS02705 38ee0a21853c249734605b3b9fd9a5fa 228 Pfam PF13432 Tetratricopeptide repeat 111 178 1.4E-10 T 29-03-2018 CVS48_RS02705 38ee0a21853c249734605b3b9fd9a5fa 228 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 107 224 1.6E-31 T 29-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal CVS48_RS02705 38ee0a21853c249734605b3b9fd9a5fa 228 SUPERFAMILY SSF48452 108 226 9.73E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS02705 38ee0a21853c249734605b3b9fd9a5fa 228 Pfam PF13174 Tetratricopeptide repeat 182 213 0.0025 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS02705 38ee0a21853c249734605b3b9fd9a5fa 228 Gene3D G3DSA:1.25.40.10 17 80 0.12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS07365 eb7da0a635820b53cf1cf29e05524814 444 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 3 99 3.0E-7 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CVS48_RS07365 eb7da0a635820b53cf1cf29e05524814 444 Pfam PF07804 HipA-like C-terminal domain 139 368 1.9E-36 T 29-03-2018 IPR012893 HipA-like, C-terminal CVS48_RS07365 eb7da0a635820b53cf1cf29e05524814 444 Pfam PF13657 HipA N-terminal domain 3 99 7.3E-13 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CVS48_RS14200 ebed2794dd25de1c92d8831354fcfecb 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 270 2.6E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS14200 ebed2794dd25de1c92d8831354fcfecb 282 Gene3D G3DSA:1.10.3720.10 10 276 1.3E-39 T 29-03-2018 CVS48_RS14200 ebed2794dd25de1c92d8831354fcfecb 282 SUPERFAMILY SSF161098 11 273 1.83E-51 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19320 107bd1d99dcfc3b2d7b2cc0dda05f3bf 362 Pfam PF00005 ABC transporter 21 162 7.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19320 107bd1d99dcfc3b2d7b2cc0dda05f3bf 362 SUPERFAMILY SSF50331 237 359 2.41E-23 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS19320 107bd1d99dcfc3b2d7b2cc0dda05f3bf 362 Gene3D G3DSA:3.40.50.300 1 239 9.8E-71 T 29-03-2018 CVS48_RS19320 107bd1d99dcfc3b2d7b2cc0dda05f3bf 362 Pfam PF08402 TOBE domain 280 346 9.0E-9 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS19320 107bd1d99dcfc3b2d7b2cc0dda05f3bf 362 Gene3D G3DSA:2.40.50.100 240 291 8.4E-8 T 29-03-2018 CVS48_RS19320 107bd1d99dcfc3b2d7b2cc0dda05f3bf 362 SUPERFAMILY SSF52540 4 245 2.66E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19320 107bd1d99dcfc3b2d7b2cc0dda05f3bf 362 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS19320 107bd1d99dcfc3b2d7b2cc0dda05f3bf 362 SMART SM00382 29 212 2.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19320 107bd1d99dcfc3b2d7b2cc0dda05f3bf 362 Gene3D G3DSA:2.40.50.140 292 341 2.5E-13 T 29-03-2018 CVS48_RS13050 1e0e53d6a3afef9387fe6313ca4b9f74 292 Pfam PF00005 ABC transporter 24 166 3.9E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13050 1e0e53d6a3afef9387fe6313ca4b9f74 292 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13050 1e0e53d6a3afef9387fe6313ca4b9f74 292 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 24 254 3.3E-101 T 29-03-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 CVS48_RS13050 1e0e53d6a3afef9387fe6313ca4b9f74 292 SMART SM00382 33 216 1.6E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13050 1e0e53d6a3afef9387fe6313ca4b9f74 292 Gene3D G3DSA:3.40.50.300 1 288 2.1E-54 T 29-03-2018 CVS48_RS13050 1e0e53d6a3afef9387fe6313ca4b9f74 292 SUPERFAMILY SSF52540 5 226 2.15E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21880 b299762abd8e3906581aaa7122d31e0a 406 Gene3D G3DSA:3.40.50.10540 1 402 9.8E-142 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS21880 b299762abd8e3906581aaa7122d31e0a 406 Pfam PF02515 CoA-transferase family III 4 369 1.7E-124 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS21880 b299762abd8e3906581aaa7122d31e0a 406 SUPERFAMILY SSF89796 2 392 1.57E-133 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 Gene3D G3DSA:1.10.10.60 254 281 0.0023 T 29-03-2018 CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 281 326 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 Pfam PF14525 AraC-binding-like domain 56 208 1.1E-6 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 SUPERFAMILY SSF46689 280 333 3.99E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 Gene3D G3DSA:1.10.10.60 282 337 1.0E-13 T 29-03-2018 CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 Gene3D G3DSA:1.10.10.60 78 253 0.48 T 29-03-2018 CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 SMART SM00342 245 330 2.5E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 5.8E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 5.8E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS11475 c697fe066762b334bbb2e264d24c0e77 337 Pfam PF12833 Helix-turn-helix domain 251 331 1.3E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS23545 7a4ddd1ad41bc3504ef70a11d4448f5c 370 PIRSF PIRSF015557 1 368 9.2E-136 T 29-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 CVS48_RS23545 7a4ddd1ad41bc3504ef70a11d4448f5c 370 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 4 364 3.6E-132 T 29-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 CVS48_RS23545 7a4ddd1ad41bc3504ef70a11d4448f5c 370 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 4 363 1.3E-129 T 29-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 CVS48_RS23560 1186b89e2b0e4053d11679f238e21967 240 Pfam PF11180 Protein of unknown function (DUF2968) 51 228 2.7E-68 T 29-03-2018 IPR021350 Protein of unknown function DUF2968 CVS48_RS23560 1186b89e2b0e4053d11679f238e21967 240 Gene3D G3DSA:1.20.1170.10 24 233 8.1E-6 T 29-03-2018 CVS48_RS12180 8f2a2b287aac405725919502f97e6132 354 SUPERFAMILY SSF55486 73 352 7.14E-81 T 29-03-2018 CVS48_RS12180 8f2a2b287aac405725919502f97e6132 354 Gene3D G3DSA:1.10.390.10 187 353 2.6E-53 T 29-03-2018 CVS48_RS12180 8f2a2b287aac405725919502f97e6132 354 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 185 352 3.3E-47 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CVS48_RS12180 8f2a2b287aac405725919502f97e6132 354 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 76 181 8.2E-28 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CVS48_RS12180 8f2a2b287aac405725919502f97e6132 354 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 137 157 3.1E-26 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CVS48_RS12180 8f2a2b287aac405725919502f97e6132 354 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 275 291 3.1E-26 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CVS48_RS12180 8f2a2b287aac405725919502f97e6132 354 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 173 189 3.1E-26 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CVS48_RS12180 8f2a2b287aac405725919502f97e6132 354 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 194 205 3.1E-26 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CVS48_RS12180 8f2a2b287aac405725919502f97e6132 354 Gene3D G3DSA:3.10.170.10 5 186 2.0E-57 T 29-03-2018 CVS48_RS16770 5f33c448f69cd8eae250d9a4d2b86b7b 193 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 175 6.7E-81 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CVS48_RS16770 5f33c448f69cd8eae250d9a4d2b86b7b 193 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 163 7.0E-82 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CVS48_RS16770 5f33c448f69cd8eae250d9a4d2b86b7b 193 SUPERFAMILY SSF160930 6 163 9.42E-59 T 29-03-2018 CVS48_RS16770 5f33c448f69cd8eae250d9a4d2b86b7b 193 PIRSF PIRSF003159 1 184 4.3E-81 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CVS48_RS16770 5f33c448f69cd8eae250d9a4d2b86b7b 193 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 189 44.743 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 Gene3D G3DSA:1.10.10.10 1 89 1.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 2.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 SUPERFAMILY SSF53850 89 297 2.17E-40 T 29-03-2018 CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 SUPERFAMILY SSF46785 5 89 1.68E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 Gene3D G3DSA:3.40.190.10 179 269 2.1E-25 T 29-03-2018 CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 Pfam PF03466 LysR substrate binding domain 90 297 3.5E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS11265 d1040b3ad4e1b8b895c0abaf0371bcc4 303 Gene3D G3DSA:3.40.190.10 90 178 1.8E-15 T 29-03-2018 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 PIRSF PIRSF500134 1 440 2.8E-192 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 SMART SM00984 320 424 4.8E-52 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 296 1.6E-38 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 Gene3D G3DSA:3.40.50.720 1 202 1.5E-61 T 29-03-2018 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 185 1.1E-63 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 PIRSF PIRSF000124 1 439 1.2E-148 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 Gene3D G3DSA:3.40.50.720 228 436 1.4E-74 T 29-03-2018 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 420 4.5E-136 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 SUPERFAMILY SSF52413 305 434 8.37E-41 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 SUPERFAMILY SSF51735 1 194 3.54E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 423 1.2E-32 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 SUPERFAMILY SSF48179 204 300 2.93E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS04895 6be0269be33f03d8b7d575949a8b1a61 440 Gene3D G3DSA:1.20.5.100 205 227 7.7E-15 T 29-03-2018 CVS48_RS18635 0db7aec1f31b952486d5ff99a4e7354c 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 274 4.4E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18635 0db7aec1f31b952486d5ff99a4e7354c 276 Gene3D G3DSA:1.10.3720.10 6 264 1.0E-35 T 29-03-2018 CVS48_RS18635 0db7aec1f31b952486d5ff99a4e7354c 276 SUPERFAMILY SSF161098 71 256 9.81E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS26760 67acb3e72f09aef6a7158518c0b1b50f 132 SUPERFAMILY SSF51182 20 118 3.49E-26 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS26760 67acb3e72f09aef6a7158518c0b1b50f 132 Pfam PF12973 ChrR Cupin-like domain 28 113 6.8E-18 T 29-03-2018 IPR025979 ChrR-like cupin domain CVS48_RS26760 67acb3e72f09aef6a7158518c0b1b50f 132 Gene3D G3DSA:2.60.120.10 7 123 3.4E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS18060 e6e0a6f06d57c67d908c79625d702773 367 Gene3D G3DSA:1.10.3720.10 26 367 2.0E-40 T 29-03-2018 CVS48_RS18060 e6e0a6f06d57c67d908c79625d702773 367 SUPERFAMILY SSF161098 156 347 3.14E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18060 e6e0a6f06d57c67d908c79625d702773 367 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 175 361 1.7E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18060 e6e0a6f06d57c67d908c79625d702773 367 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 158 253 1.5E-18 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS02610 d9b715c30fdd1c9d22a14d0e29075081 148 Gene3D G3DSA:1.20.5.50 1 77 2.3E-4 T 29-03-2018 CVS48_RS02610 d9b715c30fdd1c9d22a14d0e29075081 148 Gene3D G3DSA:1.20.5.730 78 139 0.017 T 29-03-2018 CVS48_RS13400 147fe9d43ddfb3af06f8c0b95559669b 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CVS48_RS13400 147fe9d43ddfb3af06f8c0b95559669b 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 5.3E-102 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CVS48_RS13400 147fe9d43ddfb3af06f8c0b95559669b 354 PIRSF PIRSF001359 1 329 1.1E-86 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CVS48_RS13400 147fe9d43ddfb3af06f8c0b95559669b 354 SUPERFAMILY SSF51569 1 328 5.86E-107 T 29-03-2018 CVS48_RS13400 147fe9d43ddfb3af06f8c0b95559669b 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CVS48_RS13400 147fe9d43ddfb3af06f8c0b95559669b 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 7.5E-189 T 29-03-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CVS48_RS13400 147fe9d43ddfb3af06f8c0b95559669b 354 Gene3D G3DSA:3.20.20.70 1 331 8.6E-109 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS13400 147fe9d43ddfb3af06f8c0b95559669b 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 327 4.1E-96 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CVS48_RS08125 849c86cdcb9aaca4ada2a95f7c2db8b5 547 Gene3D G3DSA:3.90.1530.10 29 141 8.7E-13 T 29-03-2018 CVS48_RS08125 849c86cdcb9aaca4ada2a95f7c2db8b5 547 SUPERFAMILY SSF110849 43 156 4.19E-7 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CVS48_RS23095 b28023456e5a9623a86bcfa858fb5af3 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 2.1E-13 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS23095 b28023456e5a9623a86bcfa858fb5af3 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 2.1E-13 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS23095 b28023456e5a9623a86bcfa858fb5af3 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 2.1E-13 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS23095 b28023456e5a9623a86bcfa858fb5af3 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 2.1E-13 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS23095 b28023456e5a9623a86bcfa858fb5af3 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 55 77 2.1E-13 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS23095 b28023456e5a9623a86bcfa858fb5af3 253 PIRSF PIRSF006648 6 253 7.2E-29 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS23095 b28023456e5a9623a86bcfa858fb5af3 253 Pfam PF01061 ABC-2 type transporter 5 216 1.3E-33 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CVS48_RS02940 4a4cc2efa80b27a9f3cd7dd7af3cc14b 419 Pfam PF04285 Protein of unknown function (DUF444) 4 417 1.4E-167 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CVS48_RS02940 4a4cc2efa80b27a9f3cd7dd7af3cc14b 419 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 419 34.843 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CVS48_RS02940 4a4cc2efa80b27a9f3cd7dd7af3cc14b 419 SUPERFAMILY SSF53300 248 356 5.34E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A CVS48_RS22990 8223c944d9dfefb283a634301a0c7cd9 317 SUPERFAMILY SSF161098 91 303 7.36E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22990 8223c944d9dfefb283a634301a0c7cd9 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 315 3.5E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22990 8223c944d9dfefb283a634301a0c7cd9 317 Gene3D G3DSA:1.10.3720.10 3 304 3.4E-39 T 29-03-2018 CVS48_RS02760 ed8fefcd9639d917be4645fad9bd5286 295 Pfam PF12146 Serine aminopeptidase, S33 81 193 1.8E-16 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CVS48_RS02760 ed8fefcd9639d917be4645fad9bd5286 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 122 4.1E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS02760 ed8fefcd9639d917be4645fad9bd5286 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 154 167 4.1E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS02760 ed8fefcd9639d917be4645fad9bd5286 295 Gene3D G3DSA:3.40.50.1820 52 294 2.8E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS02760 ed8fefcd9639d917be4645fad9bd5286 295 SUPERFAMILY SSF53474 18 285 1.05E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS28640 f0aae7b7597eef1f2d162ef51b2a11a5 494 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 10 478 7.3E-140 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CVS48_RS28640 f0aae7b7597eef1f2d162ef51b2a11a5 494 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 481 18.262 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CVS48_RS28640 f0aae7b7597eef1f2d162ef51b2a11a5 494 Pfam PF00361 Proton-conducting membrane transporter 127 429 3.5E-74 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS17640 33cef108693fb53b015b727ed3f3318b 204 Gene3D G3DSA:1.20.1260.10 2 174 5.1E-23 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS17640 33cef108693fb53b015b727ed3f3318b 204 SUPERFAMILY SSF47240 10 95 1.42E-8 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS12345 ef1956b53fc97ad1966e68ef547bce33 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 1.6E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12345 ef1956b53fc97ad1966e68ef547bce33 295 Gene3D G3DSA:3.40.190.10 99 185 6.7E-19 T 29-03-2018 CVS48_RS12345 ef1956b53fc97ad1966e68ef547bce33 295 Gene3D G3DSA:3.40.190.10 186 264 1.0E-12 T 29-03-2018 CVS48_RS12345 ef1956b53fc97ad1966e68ef547bce33 295 SUPERFAMILY SSF46785 7 119 3.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12345 ef1956b53fc97ad1966e68ef547bce33 295 Pfam PF03466 LysR substrate binding domain 97 286 2.1E-29 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS12345 ef1956b53fc97ad1966e68ef547bce33 295 Gene3D G3DSA:1.10.10.10 3 97 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12345 ef1956b53fc97ad1966e68ef547bce33 295 SUPERFAMILY SSF53850 98 290 7.71E-28 T 29-03-2018 CVS48_RS20735 c62395956b376ef56bb8ba1a0de5fcd7 591 SUPERFAMILY SSF51905 521 582 1.37E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS20735 c62395956b376ef56bb8ba1a0de5fcd7 591 SUPERFAMILY SSF51905 5 341 1.37E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS20735 c62395956b376ef56bb8ba1a0de5fcd7 591 Pfam PF05199 GMC oxidoreductase 448 571 5.0E-21 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS20735 c62395956b376ef56bb8ba1a0de5fcd7 591 SUPERFAMILY SSF54373 432 492 3.92E-6 T 29-03-2018 CVS48_RS20735 c62395956b376ef56bb8ba1a0de5fcd7 591 Pfam PF00732 GMC oxidoreductase 232 345 2.7E-11 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CVS48_RS20735 c62395956b376ef56bb8ba1a0de5fcd7 591 Gene3D G3DSA:3.50.50.60 2 587 1.9E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18235 0da85e3d815093cef3aae052edfa0f77 586 Gene3D G3DSA:3.40.50.1220 193 351 1.5E-33 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS18235 0da85e3d815093cef3aae052edfa0f77 586 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 330 6.7E-29 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS18235 0da85e3d815093cef3aae052edfa0f77 586 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 175 1.6E-51 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS18235 0da85e3d815093cef3aae052edfa0f77 586 Gene3D G3DSA:3.40.50.970 2 192 8.4E-50 T 29-03-2018 CVS48_RS18235 0da85e3d815093cef3aae052edfa0f77 586 SUPERFAMILY SSF52467 162 344 1.76E-37 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS18235 0da85e3d815093cef3aae052edfa0f77 586 SUPERFAMILY SSF52518 370 550 7.51E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS18235 0da85e3d815093cef3aae052edfa0f77 586 SUPERFAMILY SSF52518 8 191 2.4E-52 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS18235 0da85e3d815093cef3aae052edfa0f77 586 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 541 1.1E-35 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS18235 0da85e3d815093cef3aae052edfa0f77 586 Gene3D G3DSA:3.40.50.970 352 553 2.2E-34 T 29-03-2018 CVS48_RS03255 a59e792bdc1d7e359ff7378872f859da 392 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 365 1.8E-65 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 CVS48_RS03255 a59e792bdc1d7e359ff7378872f859da 392 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 368 2.5E-89 T 29-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 CVS48_RS17760 d1a944d43363e0b82024ae69c2debcff 236 Gene3D G3DSA:3.50.30.40 7 199 1.7E-50 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS17760 d1a944d43363e0b82024ae69c2debcff 236 SUPERFAMILY SSF89562 12 188 5.1E-41 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS17760 d1a944d43363e0b82024ae69c2debcff 236 Pfam PF03737 Aldolase/RraA 14 179 3.1E-32 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 Gene3D G3DSA:3.40.50.720 1 45 6.1E-11 T 29-03-2018 CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 Gene3D G3DSA:3.40.50.720 46 274 4.4E-55 T 29-03-2018 CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 SUPERFAMILY SSF51735 5 273 1.22E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 6.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 6.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.6E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.6E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 237 257 2.6E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.6E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 2.6E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.6E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 201 6.3E-5 T 29-03-2018 CVS48_RS25885 73b6c736e0dfd8a9da0e02e3a5d31c2a 274 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 272 2.4E-48 T 29-03-2018 CVS48_RS29065 f02c3c1f6f48a29a073bde058976ae83 307 Gene3D G3DSA:3.30.700.10 193 306 4.7E-6 T 29-03-2018 CVS48_RS29065 f02c3c1f6f48a29a073bde058976ae83 307 Pfam PF06271 RDD family 1 153 5.6E-11 T 29-03-2018 IPR010432 RDD CVS48_RS17095 ce5cc4193b92328c2ce76886274a0eb7 173 Pfam PF01863 Protein of unknown function DUF45 97 155 3.8E-10 T 29-03-2018 IPR002725 Protein of unknown function DUF45 CVS48_RS14190 7a8857e40ab012a1e4d635ce5348f143 337 Gene3D G3DSA:3.10.310.10 1 153 4.5E-31 T 29-03-2018 CVS48_RS14190 7a8857e40ab012a1e4d635ce5348f143 337 Gene3D G3DSA:3.10.310.10 154 312 1.0E-44 T 29-03-2018 CVS48_RS14190 7a8857e40ab012a1e4d635ce5348f143 337 PIRSF PIRSF029792 1 337 2.9E-99 T 29-03-2018 IPR008794 Proline racemase family CVS48_RS14190 7a8857e40ab012a1e4d635ce5348f143 337 SUPERFAMILY SSF54506 1 334 2.75E-93 T 29-03-2018 CVS48_RS14190 7a8857e40ab012a1e4d635ce5348f143 337 Pfam PF05544 Proline racemase 9 334 1.7E-92 T 29-03-2018 IPR008794 Proline racemase family CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 Gene3D G3DSA:3.40.50.261 135 305 5.0E-39 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 SMART SM00881 14 109 1.8E-33 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 165 301 1.1E-41 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 Pfam PF13380 CoA binding domain 19 142 4.7E-22 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 Gene3D G3DSA:3.30.470.20 568 707 9.5E-30 T 29-03-2018 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 SUPERFAMILY SSF51735 8 146 1.14E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 Gene3D G3DSA:3.30.1490.20 502 567 3.3E-5 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 SUPERFAMILY SSF52210 308 464 1.23E-26 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 Gene3D G3DSA:3.40.50.261 306 468 1.9E-27 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 SUPERFAMILY SSF56059 491 703 2.0E-29 T 29-03-2018 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 Pfam PF13549 ATP-grasp domain 489 703 1.8E-47 T 29-03-2018 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 SUPERFAMILY SSF52210 141 303 2.35E-37 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS01230 0d4d4e4ad1484d8ae5d182b4ced9a7fc 715 Gene3D G3DSA:3.40.50.720 10 134 1.0E-38 T 29-03-2018 CVS48_RS28210 b8c3afc4341b99d4072f3b52192abd7e 156 Gene3D G3DSA:3.40.50.10110 1 150 1.3E-44 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CVS48_RS28210 b8c3afc4341b99d4072f3b52192abd7e 156 SUPERFAMILY SSF102400 1 149 4.58E-37 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CVS48_RS28210 b8c3afc4341b99d4072f3b52192abd7e 156 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 143 3.8E-37 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CVS48_RS19530 fd058808f302d193676bd05d6f4e3e80 519 Pfam PF00324 Amino acid permease 33 482 4.9E-135 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CVS48_RS19530 fd058808f302d193676bd05d6f4e3e80 519 PIRSF PIRSF006060 13 500 1.4E-80 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CVS48_RS19530 fd058808f302d193676bd05d6f4e3e80 519 ProSitePatterns PS00218 Amino acid permeases signature. 58 89 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CVS48_RS00710 e78bd1eb8718310228a70a38342d4095 191 Pfam PF13470 PIN domain 9 114 2.3E-11 T 29-03-2018 IPR002716 PIN domain CVS48_RS00710 e78bd1eb8718310228a70a38342d4095 191 Gene3D G3DSA:3.40.50.1010 9 148 3.0E-5 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS17045 09a02a29eff77e7a940f24820ab2e8cd 245 Pfam PF01614 Bacterial transcriptional regulator 128 243 8.5E-19 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS17045 09a02a29eff77e7a940f24820ab2e8cd 245 Pfam PF09339 IclR helix-turn-helix domain 7 54 1.8E-9 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS17045 09a02a29eff77e7a940f24820ab2e8cd 245 Gene3D G3DSA:1.10.10.10 4 71 2.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17045 09a02a29eff77e7a940f24820ab2e8cd 245 SMART SM00346 3 93 0.0037 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS17045 09a02a29eff77e7a940f24820ab2e8cd 245 SUPERFAMILY SSF46785 3 75 1.32E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17045 09a02a29eff77e7a940f24820ab2e8cd 245 SUPERFAMILY SSF55781 77 243 7.85E-34 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS17045 09a02a29eff77e7a940f24820ab2e8cd 245 Gene3D G3DSA:3.30.450.40 72 245 1.9E-31 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS01820 18dc04dadf08adcb7972e3b37a69e4ef 349 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 347 46.502 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS01820 18dc04dadf08adcb7972e3b37a69e4ef 349 SUPERFAMILY SSF55326 9 172 4.54E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS01820 18dc04dadf08adcb7972e3b37a69e4ef 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 58 166 2.1E-14 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS01820 18dc04dadf08adcb7972e3b37a69e4ef 349 Gene3D G3DSA:3.90.650.10 173 349 3.2E-63 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS01820 18dc04dadf08adcb7972e3b37a69e4ef 349 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 338 2.0E-136 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CVS48_RS01820 18dc04dadf08adcb7972e3b37a69e4ef 349 Gene3D G3DSA:3.30.1330.10 37 163 3.3E-52 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CVS48_RS01820 18dc04dadf08adcb7972e3b37a69e4ef 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 341 5.7E-39 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS01820 18dc04dadf08adcb7972e3b37a69e4ef 349 SUPERFAMILY SSF56042 173 345 4.36E-59 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CVS48_RS01225 6c1c3424d8a5b3f411dd0dac2e72dfac 325 Gene3D G3DSA:3.40.190.10 125 253 8.1E-10 T 29-03-2018 CVS48_RS01225 6c1c3424d8a5b3f411dd0dac2e72dfac 325 SUPERFAMILY SSF53850 112 283 1.19E-13 T 29-03-2018 CVS48_RS01225 6c1c3424d8a5b3f411dd0dac2e72dfac 325 PIRSF PIRSF017082 1 325 1.3E-83 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01225 6c1c3424d8a5b3f411dd0dac2e72dfac 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 1.6E-87 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 Hamap MF_01183 Chaperone SurA [surA]. 14 510 32.642 T 29-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 SUPERFAMILY SSF54534 229 329 2.16E-25 T 29-03-2018 CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 Pfam PF13616 PPIC-type PPIASE domain 367 465 3.0E-27 T 29-03-2018 CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 SUPERFAMILY SSF109998 54 194 1.51E-38 T 29-03-2018 IPR027304 Trigger factor/SurA domain CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 SUPERFAMILY SSF109998 226 257 1.51E-38 T 29-03-2018 IPR027304 Trigger factor/SurA domain CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 Pfam PF09312 SurA N-terminal domain 54 171 2.9E-35 T 29-03-2018 IPR015391 SurA N-terminal CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 Gene3D G3DSA:3.10.50.40 220 343 1.1E-21 T 29-03-2018 CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 Gene3D G3DSA:3.10.50.40 358 508 4.1E-34 T 29-03-2018 CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 SUPERFAMILY SSF54534 367 466 1.5E-32 T 29-03-2018 CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 Pfam PF00639 PPIC-type PPIASE domain 234 327 6.0E-17 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CVS48_RS02010 39cba0b6130178bd8541c12d2a9a0d7e 520 Gene3D G3DSA:1.10.4030.10 50 177 4.4E-23 T 29-03-2018 CVS48_RS28900 fdc7971204a36d45a7454ef4ff826e4c 383 SUPERFAMILY SSF53850 53 338 5.96E-40 T 29-03-2018 CVS48_RS28900 fdc7971204a36d45a7454ef4ff826e4c 383 Gene3D G3DSA:3.40.190.10 171 312 6.4E-15 T 29-03-2018 CVS48_RS28900 fdc7971204a36d45a7454ef4ff826e4c 383 Pfam PF13531 Bacterial extracellular solute-binding protein 54 319 4.5E-18 T 29-03-2018 CVS48_RS28900 fdc7971204a36d45a7454ef4ff826e4c 383 Gene3D G3DSA:3.40.190.10 47 170 3.3E-10 T 29-03-2018 CVS48_RS28320 aeed8f6ca92fe4b19b10e279601189c9 311 PIRSF PIRSF000446 1 309 3.4E-108 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CVS48_RS28320 aeed8f6ca92fe4b19b10e279601189c9 311 SUPERFAMILY SSF55048 126 195 1.44E-17 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CVS48_RS28320 aeed8f6ca92fe4b19b10e279601189c9 311 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 289 5.0E-104 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CVS48_RS28320 aeed8f6ca92fe4b19b10e279601189c9 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 311 6.3E-30 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CVS48_RS28320 aeed8f6ca92fe4b19b10e279601189c9 311 Gene3D G3DSA:3.40.366.10 1 179 5.2E-46 T 29-03-2018 CVS48_RS28320 aeed8f6ca92fe4b19b10e279601189c9 311 Gene3D G3DSA:3.40.366.10 180 310 8.8E-29 T 29-03-2018 CVS48_RS28320 aeed8f6ca92fe4b19b10e279601189c9 311 SUPERFAMILY SSF52151 2 126 1.69E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CVS48_RS28320 aeed8f6ca92fe4b19b10e279601189c9 311 SUPERFAMILY SSF52151 196 295 1.69E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CVS48_RS28320 aeed8f6ca92fe4b19b10e279601189c9 311 Pfam PF00698 Acyl transferase domain 5 276 2.3E-36 T 29-03-2018 IPR014043 Acyl transferase CVS48_RS14025 59ed277bd27b88a577621c9645a0a376 312 PIRSF PIRSF017082 2 311 7.0E-70 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS14025 59ed277bd27b88a577621c9645a0a376 312 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 35 306 9.2E-70 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS14025 59ed277bd27b88a577621c9645a0a376 312 SUPERFAMILY SSF53850 115 273 4.43E-9 T 29-03-2018 CVS48_RS14025 59ed277bd27b88a577621c9645a0a376 312 Gene3D G3DSA:3.40.190.10 114 221 1.1E-9 T 29-03-2018 CVS48_RS25805 706b005f584134b93586e63e50209c50 125 Pfam PF00072 Response regulator receiver domain 13 115 1.4E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25805 706b005f584134b93586e63e50209c50 125 SMART SM00448 10 119 0.0022 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25805 706b005f584134b93586e63e50209c50 125 Gene3D G3DSA:3.40.50.2300 6 121 3.6E-9 T 29-03-2018 CVS48_RS25805 706b005f584134b93586e63e50209c50 125 SUPERFAMILY SSF52172 9 120 3.27E-13 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 SUPERFAMILY SSF46785 13 123 2.97E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 Pfam PF03466 LysR substrate binding domain 102 311 1.3E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 74 8.7E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 Gene3D G3DSA:3.40.190.10 101 188 5.4E-15 T 29-03-2018 CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 SUPERFAMILY SSF53850 102 311 3.12E-36 T 29-03-2018 CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 Gene3D G3DSA:1.10.10.10 10 97 4.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 Gene3D G3DSA:3.40.190.10 189 283 7.3E-15 T 29-03-2018 CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 4.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 4.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS23125 db2d67e0a3c4ab059097e8ec7212f466 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 4.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 SUPERFAMILY SSF51246 330 445 6.8E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 Gene3D G3DSA:3.30.1490.20 123 208 5.6E-16 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 Gene3D G3DSA:3.40.50.20 1 122 3.2E-48 T 29-03-2018 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 Pfam PF02785 Biotin carboxylase C-terminal domain 334 444 3.4E-37 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.2E-42 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 Gene3D G3DSA:3.30.470.20 209 447 4.7E-95 T 29-03-2018 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 4.4E-75 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 SUPERFAMILY SSF51230 502 574 8.9E-16 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 Pfam PF00364 Biotin-requiring enzyme 510 574 6.3E-13 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 SUPERFAMILY SSF52440 1 112 8.63E-47 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 SMART SM00878 334 444 2.7E-60 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 SUPERFAMILY SSF56059 82 330 4.42E-59 T 29-03-2018 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 Gene3D G3DSA:2.40.50.100 505 575 4.1E-17 T 29-03-2018 CVS48_RS18480 27a46c0d8915d21b35943286afe8d676 575 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 532 549 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 Gene3D G3DSA:1.10.10.60 212 260 1.6E-10 T 29-03-2018 CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 SUPERFAMILY SSF46689 210 257 1.16E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 Gene3D G3DSA:2.60.120.10 7 162 2.8E-12 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 SMART SM00342 173 255 6.6E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 Pfam PF02311 AraC-like ligand binding domain 30 80 3.2E-7 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 210 251 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 224 239 2.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 255 2.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 Pfam PF12833 Helix-turn-helix domain 179 256 2.3E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 SUPERFAMILY SSF51182 17 188 8.3E-17 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS02275 5d075528a4431fd0bba5c66d13f59848 261 Gene3D G3DSA:1.10.10.60 163 211 4.3E-13 T 29-03-2018 CVS48_RS22310 ac15a518661d0bd5fe404a34770f16dd 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 6.7E-26 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS22310 ac15a518661d0bd5fe404a34770f16dd 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 217 2.6E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22310 ac15a518661d0bd5fe404a34770f16dd 223 SUPERFAMILY SSF161098 16 217 4.84E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22310 ac15a518661d0bd5fe404a34770f16dd 223 Gene3D G3DSA:1.10.3720.10 2 221 3.5E-40 T 29-03-2018 CVS48_RS22310 ac15a518661d0bd5fe404a34770f16dd 223 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 5 216 4.5E-95 T 29-03-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD CVS48_RS10820 b93c89c8db17f180d81e8a2b9f5ed0b9 317 Gene3D G3DSA:3.60.15.10 11 240 2.2E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS10820 b93c89c8db17f180d81e8a2b9f5ed0b9 317 SUPERFAMILY SSF56281 14 309 1.04E-56 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS10820 b93c89c8db17f180d81e8a2b9f5ed0b9 317 Pfam PF00753 Metallo-beta-lactamase superfamily 33 219 1.1E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS10820 b93c89c8db17f180d81e8a2b9f5ed0b9 317 SMART SM00849 33 220 2.5E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS24245 d0b0a6ad11dd99e263d279f5e75dd3bd 473 Pfam PF00474 Sodium:solute symporter family 37 422 7.7E-21 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 SUPERFAMILY SSF46785 7 87 4.22E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 Gene3D G3DSA:3.40.190.10 184 276 8.7E-10 T 29-03-2018 CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.4E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.4E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.4E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 Pfam PF03466 LysR substrate binding domain 95 301 1.4E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 SUPERFAMILY SSF53850 97 305 1.63E-32 T 29-03-2018 CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 Gene3D G3DSA:1.10.10.10 3 90 1.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 5.0E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22680 f93597daaefc8fa362abbd91efca803c 329 Gene3D G3DSA:3.40.190.10 96 183 1.3E-17 T 29-03-2018 CVS48_RS09410 21ff6dc699a9c683164204c2cd0321c1 212 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 73 6.1E-16 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS09410 21ff6dc699a9c683164204c2cd0321c1 212 Gene3D G3DSA:3.40.30.10 1 96 2.1E-28 T 29-03-2018 CVS48_RS09410 21ff6dc699a9c683164204c2cd0321c1 212 SUPERFAMILY SSF47616 80 210 7.82E-35 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS09410 21ff6dc699a9c683164204c2cd0321c1 212 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 210 1.5E-86 T 29-03-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 CVS48_RS09410 21ff6dc699a9c683164204c2cd0321c1 212 Gene3D G3DSA:1.20.1050.10 97 212 4.4E-30 T 29-03-2018 CVS48_RS09410 21ff6dc699a9c683164204c2cd0321c1 212 SUPERFAMILY SSF52833 1 84 7.63E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS09410 21ff6dc699a9c683164204c2cd0321c1 212 Pfam PF14497 Glutathione S-transferase, C-terminal domain 124 199 6.8E-8 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS07025 05a626618fd13921fe43dc3a9782b0a4 602 Gene3D G3DSA:3.40.50.2000 381 571 2.8E-8 T 29-03-2018 CVS48_RS07025 05a626618fd13921fe43dc3a9782b0a4 602 SUPERFAMILY SSF53756 279 588 4.6E-16 T 29-03-2018 CVS48_RS14995 580e0e9bf2da8273bff2c202033f9762 220 Gene3D G3DSA:3.20.20.70 2 215 1.9E-62 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS14995 580e0e9bf2da8273bff2c202033f9762 220 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 213 38.184 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CVS48_RS14995 580e0e9bf2da8273bff2c202033f9762 220 SUPERFAMILY SSF51366 3 210 6.28E-54 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CVS48_RS14995 580e0e9bf2da8273bff2c202033f9762 220 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 208 8.5E-42 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CVS48_RS21265 97a27ebbdf04826f8f7500995224191d 489 Gene3D G3DSA:3.40.630.10 23 224 5.3E-20 T 29-03-2018 CVS48_RS21265 97a27ebbdf04826f8f7500995224191d 489 Pfam PF01546 Peptidase family M20/M25/M40 107 484 8.6E-22 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS21265 97a27ebbdf04826f8f7500995224191d 489 Gene3D G3DSA:3.30.70.360 225 396 2.1E-39 T 29-03-2018 CVS48_RS21265 97a27ebbdf04826f8f7500995224191d 489 Pfam PF07687 Peptidase dimerisation domain 219 383 8.5E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS21265 97a27ebbdf04826f8f7500995224191d 489 SUPERFAMILY SSF53187 25 221 1.0E-43 T 29-03-2018 CVS48_RS21265 97a27ebbdf04826f8f7500995224191d 489 SUPERFAMILY SSF53187 401 485 1.0E-43 T 29-03-2018 CVS48_RS15985 8922596dd2647ceda0737c88c62fd0d4 483 Pfam PF00474 Sodium:solute symporter family 36 408 1.0E-21 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS22875 e65e4a9068afce5e1459e7874763b627 120 Gene3D G3DSA:2.60.40.1180 47 116 2.8E-7 T 29-03-2018 CVS48_RS22875 e65e4a9068afce5e1459e7874763b627 120 SUPERFAMILY SSF81901 54 116 1.19E-8 T 29-03-2018 CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 Gene3D G3DSA:3.30.70.120 1 109 3.4E-47 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 PIRSF PIRSF039144 1 112 1.9E-52 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 SUPERFAMILY SSF54913 1 112 1.43E-43 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 SMART SM00938 4 105 1.9E-63 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 PRINTS PR00340 P-II protein signature 52 75 5.8E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 PRINTS PR00340 P-II protein signature 2 17 5.8E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 PRINTS PR00340 P-II protein signature 83 103 5.8E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 PRINTS PR00340 P-II protein signature 23 41 5.8E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.6E-41 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS15155 b54efe164e8566c46a00208727c93bee 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CVS48_RS11680 e66ba1a214396bda066b880e97b9295c 533 Gene3D G3DSA:3.40.309.10 281 458 6.4E-23 T 29-03-2018 CVS48_RS11680 e66ba1a214396bda066b880e97b9295c 533 SUPERFAMILY SSF53720 20 522 1.44E-97 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS11680 e66ba1a214396bda066b880e97b9295c 533 Pfam PF00171 Aldehyde dehydrogenase family 18 470 6.5E-46 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS11680 e66ba1a214396bda066b880e97b9295c 533 Gene3D G3DSA:3.40.605.10 3 280 1.3E-47 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS01235 eabe37e76a2d90763b3527521d2dcde1 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 2.8E-91 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01235 eabe37e76a2d90763b3527521d2dcde1 323 PIRSF PIRSF017082 1 322 3.1E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01235 eabe37e76a2d90763b3527521d2dcde1 323 Gene3D G3DSA:3.40.190.10 124 233 9.0E-11 T 29-03-2018 CVS48_RS01235 eabe37e76a2d90763b3527521d2dcde1 323 SUPERFAMILY SSF53850 81 283 2.47E-13 T 29-03-2018 CVS48_RS15365 c745e1f328369e678835b814ccfd5f3d 416 Pfam PF07690 Major Facilitator Superfamily 39 270 2.4E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS15365 c745e1f328369e678835b814ccfd5f3d 416 Gene3D G3DSA:1.20.1250.20 219 413 4.9E-22 T 29-03-2018 CVS48_RS15365 c745e1f328369e678835b814ccfd5f3d 416 Gene3D G3DSA:1.20.1250.20 24 212 8.1E-20 T 29-03-2018 CVS48_RS15365 c745e1f328369e678835b814ccfd5f3d 416 SUPERFAMILY SSF103473 20 410 9.42E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 SUPERFAMILY SSF56601 6 278 5.64E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 257 3.5E-75 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 278 365 5.5E-16 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 58 69 4.3E-19 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 140 153 4.3E-19 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 113 130 4.3E-19 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 Gene3D G3DSA:2.60.410.10 278 366 7.6E-17 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 Gene3D G3DSA:3.40.710.10 13 277 3.4E-51 T 29-03-2018 CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 SUPERFAMILY SSF69189 278 368 5.1E-19 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS25975 a0da77cba30ecb6334d12d9301b806c8 386 SMART SM00936 278 366 1.4E-23 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CVS48_RS25380 057420d23a8837bd7b25934914bddce7 320 Pfam PF00795 Carbon-nitrogen hydrolase 13 286 4.2E-48 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS25380 057420d23a8837bd7b25934914bddce7 320 Gene3D G3DSA:3.60.110.10 8 307 3.0E-61 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS25380 057420d23a8837bd7b25934914bddce7 320 SUPERFAMILY SSF56317 9 306 4.32E-70 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS14175 97e8ac270958662b3d72e7f91442697d 328 Pfam PF02780 Transketolase, C-terminal domain 197 318 3.0E-30 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CVS48_RS14175 97e8ac270958662b3d72e7f91442697d 328 Gene3D G3DSA:3.40.50.970 28 192 2.1E-39 T 29-03-2018 CVS48_RS14175 97e8ac270958662b3d72e7f91442697d 328 SUPERFAMILY SSF52518 26 188 1.25E-48 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS14175 97e8ac270958662b3d72e7f91442697d 328 Pfam PF02779 Transketolase, pyrimidine binding domain 27 181 5.0E-35 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS14175 97e8ac270958662b3d72e7f91442697d 328 Gene3D G3DSA:3.40.50.920 197 328 4.8E-34 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS14175 97e8ac270958662b3d72e7f91442697d 328 SMART SM00861 21 186 2.0E-41 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CVS48_RS14175 97e8ac270958662b3d72e7f91442697d 328 SUPERFAMILY SSF52922 193 326 3.01E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS08875 8b35b74cbc36f6f9a996f6c82e094148 349 SUPERFAMILY SSF53850 35 342 2.17E-58 T 29-03-2018 CVS48_RS08875 8b35b74cbc36f6f9a996f6c82e094148 349 Gene3D G3DSA:3.40.190.10 30 152 6.0E-8 T 29-03-2018 CVS48_RS08875 8b35b74cbc36f6f9a996f6c82e094148 349 Gene3D G3DSA:3.40.190.10 153 304 1.2E-38 T 29-03-2018 CVS48_RS08875 8b35b74cbc36f6f9a996f6c82e094148 349 Pfam PF13416 Bacterial extracellular solute-binding protein 60 311 2.3E-30 T 29-03-2018 CVS48_RS05135 af9419a4171e35f7622e0a8381572948 116 Gene3D G3DSA:1.10.287.1080 8 103 6.8E-22 T 29-03-2018 CVS48_RS05135 af9419a4171e35f7622e0a8381572948 116 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 9 98 20.462 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CVS48_RS05135 af9419a4171e35f7622e0a8381572948 116 SUPERFAMILY SSF101386 16 102 3.74E-22 T 29-03-2018 CVS48_RS05135 af9419a4171e35f7622e0a8381572948 116 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 17 101 2.8E-14 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CVS48_RS05135 af9419a4171e35f7622e0a8381572948 116 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 12 98 1.1E-26 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CVS48_RS01845 1d0b04753c053713de98a46289643e33 298 Gene3D G3DSA:3.40.1190.20 3 293 1.7E-46 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS01845 1d0b04753c053713de98a46289643e33 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 233 246 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CVS48_RS01845 1d0b04753c053713de98a46289643e33 298 Pfam PF00294 pfkB family carbohydrate kinase 3 282 1.2E-21 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CVS48_RS01845 1d0b04753c053713de98a46289643e33 298 SUPERFAMILY SSF53613 3 290 8.73E-50 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS01845 1d0b04753c053713de98a46289643e33 298 PRINTS PR00990 Ribokinase signature 33 52 1.7E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CVS48_RS01845 1d0b04753c053713de98a46289643e33 298 PRINTS PR00990 Ribokinase signature 6 27 1.7E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CVS48_RS01845 1d0b04753c053713de98a46289643e33 298 PRINTS PR00990 Ribokinase signature 200 211 1.7E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CVS48_RS12685 49dcbf9f164fb17ac9ca0f2bbcfce73f 170 Gene3D G3DSA:1.10.1740.10 2 72 1.5E-19 T 29-03-2018 CVS48_RS12685 49dcbf9f164fb17ac9ca0f2bbcfce73f 170 SUPERFAMILY SSF88946 6 79 3.14E-18 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12685 49dcbf9f164fb17ac9ca0f2bbcfce73f 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 154 4.0E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12685 49dcbf9f164fb17ac9ca0f2bbcfce73f 170 Pfam PF08281 Sigma-70, region 4 102 153 6.1E-20 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12685 49dcbf9f164fb17ac9ca0f2bbcfce73f 170 Pfam PF04542 Sigma-70 region 2 9 76 9.2E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12685 49dcbf9f164fb17ac9ca0f2bbcfce73f 170 SUPERFAMILY SSF88659 97 157 1.33E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12685 49dcbf9f164fb17ac9ca0f2bbcfce73f 170 Gene3D G3DSA:1.10.10.10 73 160 5.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10925 051b7a464d4107a05be31c76bcee473e 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.1E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10925 051b7a464d4107a05be31c76bcee473e 307 Gene3D G3DSA:1.10.10.10 2 84 5.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10925 051b7a464d4107a05be31c76bcee473e 307 SUPERFAMILY SSF46785 4 88 2.35E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10925 051b7a464d4107a05be31c76bcee473e 307 Gene3D G3DSA:3.40.190.10 177 261 5.9E-16 T 29-03-2018 CVS48_RS10925 051b7a464d4107a05be31c76bcee473e 307 SUPERFAMILY SSF53850 89 292 2.02E-40 T 29-03-2018 CVS48_RS10925 051b7a464d4107a05be31c76bcee473e 307 Pfam PF03466 LysR substrate binding domain 88 288 1.7E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS10925 051b7a464d4107a05be31c76bcee473e 307 Gene3D G3DSA:3.40.190.10 85 176 7.6E-15 T 29-03-2018 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 Pfam PF00206 Lyase 22 315 6.3E-74 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 Gene3D G3DSA:1.10.40.30 390 447 4.4E-29 T 29-03-2018 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 Hamap MF_00006 Argininosuccinate lyase [argH]. 17 468 43.275 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 ProSitePatterns PS00163 Fumarate lyases signature. 290 299 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 6.8E-29 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00149 Fumarate lyase superfamily signature 162 180 6.8E-29 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00149 Fumarate lyase superfamily signature 246 273 6.8E-29 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00149 Fumarate lyase superfamily signature 290 306 6.8E-29 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 SUPERFAMILY SSF48557 19 464 2.36E-149 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 TIGRFAM TIGR00838 argH: argininosuccinate lyase 19 464 1.4E-186 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 Gene3D G3DSA:1.10.275.10 17 121 3.3E-36 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 Pfam PF14698 Argininosuccinate lyase C-terminal 378 446 2.4E-26 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 Gene3D G3DSA:1.20.200.10 122 389 1.7E-100 T 29-03-2018 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00145 Argininosuccinate lyase family signature 246 270 3.1E-67 T 29-03-2018 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00145 Argininosuccinate lyase family signature 116 138 3.1E-67 T 29-03-2018 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00145 Argininosuccinate lyase family signature 157 177 3.1E-67 T 29-03-2018 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00145 Argininosuccinate lyase family signature 290 306 3.1E-67 T 29-03-2018 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00145 Argininosuccinate lyase family signature 325 344 3.1E-67 T 29-03-2018 CVS48_RS16115 0985c5a10f7c40a36c7b569da435dc27 473 PRINTS PR00145 Argininosuccinate lyase family signature 208 224 3.1E-67 T 29-03-2018 CVS48_RS21360 b73139e2f4b5cf7d75e3811b98fc717a 360 Gene3D G3DSA:3.40.50.360 79 347 1.0E-29 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS21360 b73139e2f4b5cf7d75e3811b98fc717a 360 Pfam PF03358 NADPH-dependent FMN reductase 102 309 3.2E-29 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CVS48_RS21360 b73139e2f4b5cf7d75e3811b98fc717a 360 SUPERFAMILY SSF52218 98 229 2.68E-26 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS21360 b73139e2f4b5cf7d75e3811b98fc717a 360 SUPERFAMILY SSF52218 256 344 2.68E-26 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS01220 334490ba4860bec3069422965f03e1bd 452 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 10 366 5.2E-121 T 29-03-2018 IPR010839 Acyclic terpene utilisation CVS48_RS01220 334490ba4860bec3069422965f03e1bd 452 Gene3D G3DSA:3.40.50.720 95 432 0.011 T 29-03-2018 CVS48_RS20525 2cc4eb002fbc4c2dde79853330f5e5e6 210 Gene3D G3DSA:2.130.10.10 155 209 0.002 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS20525 2cc4eb002fbc4c2dde79853330f5e5e6 210 SUPERFAMILY SSF63829 18 207 3.99E-26 T 29-03-2018 CVS48_RS20525 2cc4eb002fbc4c2dde79853330f5e5e6 210 Gene3D G3DSA:2.130.10.10 17 154 2.8E-19 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS17535 b137e92420eaa11fc46732150e10fe6b 233 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 49 199 1.7E-52 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS17535 b137e92420eaa11fc46732150e10fe6b 233 Pfam PF01625 Peptide methionine sulfoxide reductase 49 201 7.2E-59 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS17535 b137e92420eaa11fc46732150e10fe6b 233 Gene3D G3DSA:3.30.1060.10 34 216 1.0E-63 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS17535 b137e92420eaa11fc46732150e10fe6b 233 SUPERFAMILY SSF55068 38 211 1.07E-67 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS17535 b137e92420eaa11fc46732150e10fe6b 233 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 47 207 36.064 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS26190 5e67da11b0a74905ffea5a936eae7aef 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.703 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CVS48_RS26190 5e67da11b0a74905ffea5a936eae7aef 90 SUPERFAMILY SSF111148 1 89 5.62E-38 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CVS48_RS26190 5e67da11b0a74905ffea5a936eae7aef 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 4.0E-41 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CVS48_RS26190 5e67da11b0a74905ffea5a936eae7aef 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 6.0E-37 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CVS48_RS26190 5e67da11b0a74905ffea5a936eae7aef 90 PIRSF PIRSF029827 1 90 5.5E-41 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CVS48_RS26190 5e67da11b0a74905ffea5a936eae7aef 90 Gene3D G3DSA:1.10.3880.10 2 89 1.2E-39 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CVS48_RS27630 eff9e3c5ad01689dbb4a048ee1120e79 66 SUPERFAMILY SSF69047 1 65 1.31E-25 T 29-03-2018 IPR008462 CsbD-like domain CVS48_RS27630 eff9e3c5ad01689dbb4a048ee1120e79 66 Gene3D G3DSA:1.10.1470.10 1 65 3.6E-21 T 29-03-2018 IPR008462 CsbD-like domain CVS48_RS27630 eff9e3c5ad01689dbb4a048ee1120e79 66 PIRSF PIRSF039008 1 66 2.2E-31 T 29-03-2018 IPR026042 Stress response protein YjbJ CVS48_RS27630 eff9e3c5ad01689dbb4a048ee1120e79 66 Pfam PF05532 CsbD-like 4 56 1.0E-20 T 29-03-2018 IPR008462 CsbD-like domain CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 Gene3D G3DSA:3.40.50.620 4 126 6.4E-43 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 Gene3D G3DSA:1.10.10.350 378 467 6.5E-19 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 9 465 3.7E-166 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 SUPERFAMILY SSF52374 9 305 8.85E-112 T 29-03-2018 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 8 468 30.822 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 Gene3D G3DSA:1.10.1160.10 242 324 5.3E-33 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 SUPERFAMILY SSF48163 309 466 2.35E-38 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 12 24 5.6E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 26 37 5.6E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 189 199 5.6E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 54 5.6E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 205 213 5.6E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 Gene3D G3DSA:3.40.50.620 127 241 8.7E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS03090 c734753d06346d5e38dca381ceeab47a 468 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 315 6.1E-106 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CVS48_RS14015 8d0b2deab94d3659d52e5044b149c308 318 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 20 36 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CVS48_RS14015 8d0b2deab94d3659d52e5044b149c308 318 Gene3D G3DSA:3.20.20.70 8 291 6.0E-78 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS14015 8d0b2deab94d3659d52e5044b149c308 318 Pfam PF00682 HMGL-like 17 286 1.2E-45 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CVS48_RS14015 8d0b2deab94d3659d52e5044b149c308 318 SUPERFAMILY SSF51569 6 288 5.86E-67 T 29-03-2018 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 Gene3D G3DSA:3.40.50.720 1 124 2.0E-39 T 29-03-2018 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 Pfam PF02629 CoA binding domain 6 102 1.5E-23 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 Pfam PF00549 CoA-ligase 156 271 1.7E-15 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 PIRSF PIRSF001553 1 293 8.5E-117 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 157 186 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 293 2.0E-127 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 SUPERFAMILY SSF51735 1 127 4.34E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 Gene3D G3DSA:3.40.50.261 125 293 6.4E-51 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 241 254 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 SUPERFAMILY SSF52210 128 291 8.77E-52 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 293 40.651 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 3.3E-34 T 29-03-2018 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 PRINTS PR01798 Succinyl-CoA synthase signature 182 200 3.3E-34 T 29-03-2018 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 PRINTS PR01798 Succinyl-CoA synthase signature 213 226 3.3E-34 T 29-03-2018 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 PRINTS PR01798 Succinyl-CoA synthase signature 245 262 3.3E-34 T 29-03-2018 CVS48_RS26815 18f3b5b297f14571428ffdb69069faf4 293 SMART SM00881 4 103 2.8E-29 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS01495 32fa37c8aea0473f5cd9658413618004 74 ProDom PD052686 LIPOPROTEIN INDUCIBLE OSMOTICALLY B PRECURSOR SIGNAL MEMBRANE PALMITATE TRANSMEMBRANE SURFACE 8 35 0.002 T 29-03-2018 CVS48_RS01495 32fa37c8aea0473f5cd9658413618004 74 Pfam PF05433 Glycine zipper 2TM domain 34 72 1.2E-7 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CVS48_RS07420 357e0879e0cbfc077d89bfbdb7485ccc 280 Gene3D G3DSA:3.20.20.220 1 280 1.9E-97 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CVS48_RS07420 357e0879e0cbfc077d89bfbdb7485ccc 280 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 9 278 1.2E-98 T 29-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CVS48_RS07420 357e0879e0cbfc077d89bfbdb7485ccc 280 Pfam PF02219 Methylenetetrahydrofolate reductase 4 278 1.3E-90 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CVS48_RS07420 357e0879e0cbfc077d89bfbdb7485ccc 280 SUPERFAMILY SSF51730 3 278 2.35E-96 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CVS48_RS28140 c128a735b32e3a993c4035a37de66468 336 Gene3D G3DSA:3.40.640.10 1 245 5.5E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS28140 c128a735b32e3a993c4035a37de66468 336 PIRSF PIRSF017617 1 336 5.3E-134 T 29-03-2018 IPR023603 Threonine aldolase CVS48_RS28140 c128a735b32e3a993c4035a37de66468 336 Gene3D G3DSA:3.90.1150.10 246 336 9.1E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS28140 c128a735b32e3a993c4035a37de66468 336 Pfam PF01212 Beta-eliminating lyase 3 283 3.0E-89 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CVS48_RS28140 c128a735b32e3a993c4035a37de66468 336 SUPERFAMILY SSF53383 1 335 2.09E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS20785 c00d4f70eea1c1aa528fc8446c74a8e9 295 Gene3D G3DSA:1.10.10.10 1 92 1.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20785 c00d4f70eea1c1aa528fc8446c74a8e9 295 Gene3D G3DSA:3.40.190.10 93 183 1.2E-12 T 29-03-2018 CVS48_RS20785 c00d4f70eea1c1aa528fc8446c74a8e9 295 Pfam PF03466 LysR substrate binding domain 94 286 1.6E-23 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20785 c00d4f70eea1c1aa528fc8446c74a8e9 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 1.1E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20785 c00d4f70eea1c1aa528fc8446c74a8e9 295 Gene3D G3DSA:3.40.190.10 184 260 4.8E-5 T 29-03-2018 CVS48_RS20785 c00d4f70eea1c1aa528fc8446c74a8e9 295 SUPERFAMILY SSF53850 95 289 6.33E-26 T 29-03-2018 CVS48_RS20785 c00d4f70eea1c1aa528fc8446c74a8e9 295 SUPERFAMILY SSF46785 7 117 6.51E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28145 d622b56f94e4002dae0b2f18835b1d1c 298 SUPERFAMILY SSF103481 186 288 2.48E-16 T 29-03-2018 CVS48_RS28145 d622b56f94e4002dae0b2f18835b1d1c 298 Pfam PF00892 EamA-like transporter family 150 286 6.1E-27 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS28145 d622b56f94e4002dae0b2f18835b1d1c 298 Pfam PF00892 EamA-like transporter family 10 138 2.1E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS28145 d622b56f94e4002dae0b2f18835b1d1c 298 SUPERFAMILY SSF103481 43 140 2.75E-15 T 29-03-2018 CVS48_RS18230 3553556eb94d837411e097ccac9e3de9 416 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 10 406 4.7E-126 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CVS48_RS18230 3553556eb94d837411e097ccac9e3de9 416 Gene3D G3DSA:3.40.630.10 243 414 3.7E-24 T 29-03-2018 CVS48_RS18230 3553556eb94d837411e097ccac9e3de9 416 Gene3D G3DSA:3.40.630.10 2 242 1.3E-44 T 29-03-2018 CVS48_RS18230 3553556eb94d837411e097ccac9e3de9 416 SUPERFAMILY SSF55031 213 329 1.2E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS18230 3553556eb94d837411e097ccac9e3de9 416 Pfam PF01546 Peptidase family M20/M25/M40 80 405 1.6E-38 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS18230 3553556eb94d837411e097ccac9e3de9 416 SUPERFAMILY SSF53187 336 409 3.43E-95 T 29-03-2018 CVS48_RS18230 3553556eb94d837411e097ccac9e3de9 416 SUPERFAMILY SSF53187 4 223 3.43E-95 T 29-03-2018 CVS48_RS18230 3553556eb94d837411e097ccac9e3de9 416 Pfam PF07687 Peptidase dimerisation domain 210 313 1.1E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS18230 3553556eb94d837411e097ccac9e3de9 416 PIRSF PIRSF001235 4 413 3.9E-133 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CVS48_RS28430 110f4086658d1b223ce14edcb5828f04 116 Gene3D G3DSA:3.30.1330.40 3 116 1.0E-24 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS28430 110f4086658d1b223ce14edcb5828f04 116 SUPERFAMILY SSF55298 11 116 6.44E-28 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS28430 110f4086658d1b223ce14edcb5828f04 116 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 92 110 - T 29-03-2018 IPR019897 RidA, conserved site CVS48_RS28430 110f4086658d1b223ce14edcb5828f04 116 Pfam PF01042 Endoribonuclease L-PSP 6 115 4.4E-24 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS07430 a04333e6e642846d49af506013a35b4f 287 SUPERFAMILY SSF56235 2 240 3.18E-33 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS07430 a04333e6e642846d49af506013a35b4f 287 Gene3D G3DSA:3.60.20.10 2 222 1.3E-37 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS07430 a04333e6e642846d49af506013a35b4f 287 Pfam PF00227 Proteasome subunit 102 183 5.1E-5 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CVS48_RS07430 a04333e6e642846d49af506013a35b4f 287 PIRSF PIRSF009120 1 248 4.0E-112 T 29-03-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 SUPERFAMILY SSF52540 7 257 1.52E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 271 4.7E-5 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 Pfam PF00005 ABC transporter 328 482 4.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 Pfam PF00005 ABC transporter 28 185 1.1E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 Gene3D G3DSA:3.40.50.300 298 563 6.7E-72 T 29-03-2018 CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 Gene3D G3DSA:3.40.50.300 5 297 7.3E-68 T 29-03-2018 CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 SUPERFAMILY SSF52540 300 552 1.98E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 SMART SM00382 336 531 7.9E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS23655 9a44b10596332793fdbf9cb7eebfe58d 568 SMART SM00382 36 235 1.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16175 ea3798653c9acc6df348489a2893f856 116 Pfam PF02501 Type II secretion system (T2SS), protein I 32 112 2.0E-17 T 29-03-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 CVS48_RS16175 ea3798653c9acc6df348489a2893f856 116 SUPERFAMILY SSF54523 31 105 1.57E-11 T 29-03-2018 CVS48_RS16175 ea3798653c9acc6df348489a2893f856 116 TIGRFAM TIGR01707 gspI: type II secretion system protein I 1 94 3.6E-17 T 29-03-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 CVS48_RS16175 ea3798653c9acc6df348489a2893f856 116 Gene3D G3DSA:3.30.1300.30 25 113 2.1E-17 T 29-03-2018 CVS48_RS28780 a93dc585511e0f19656f59ad06ecdf1f 656 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 52 497 3.2E-162 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CVS48_RS28780 a93dc585511e0f19656f59ad06ecdf1f 656 ProSitePatterns PS01303 BCCT family of transporters signature. 314 323 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CVS48_RS28780 a93dc585511e0f19656f59ad06ecdf1f 656 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 14 495 7.3E-201 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CVS48_RS05535 cd5a4b240795a125526ba12158167f72 183 Gene3D G3DSA:3.40.50.880 1 182 1.5E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS05535 cd5a4b240795a125526ba12158167f72 183 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 8 179 1.8E-44 T 29-03-2018 IPR006286 Peptidase C56, PfpI CVS48_RS05535 cd5a4b240795a125526ba12158167f72 183 Pfam PF01965 DJ-1/PfpI family 9 176 7.6E-48 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS05535 cd5a4b240795a125526ba12158167f72 183 SUPERFAMILY SSF52317 8 179 2.66E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS26705 37008034d8ae44ff2b93b500c64f2817 395 Gene3D G3DSA:3.40.640.10 42 277 5.7E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS26705 37008034d8ae44ff2b93b500c64f2817 395 SUPERFAMILY SSF53383 1 389 4.03E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS26705 37008034d8ae44ff2b93b500c64f2817 395 Pfam PF00155 Aminotransferase class I and II 31 375 3.1E-56 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS26705 37008034d8ae44ff2b93b500c64f2817 395 Gene3D G3DSA:3.90.1150.10 278 392 6.6E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS12225 a3247c72cefb267eb4fa7464633ce1f1 827 Pfam PF00593 TonB dependent receptor 366 823 2.1E-51 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12225 a3247c72cefb267eb4fa7464633ce1f1 827 SMART SM00965 82 133 4.9E-10 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS12225 a3247c72cefb267eb4fa7464633ce1f1 827 Gene3D G3DSA:2.170.130.10 135 287 3.2E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS12225 a3247c72cefb267eb4fa7464633ce1f1 827 Pfam PF07715 TonB-dependent Receptor Plug Domain 175 277 5.3E-12 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS12225 a3247c72cefb267eb4fa7464633ce1f1 827 Pfam PF07660 Secretin and TonB N terminus short domain 88 132 8.5E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS12225 a3247c72cefb267eb4fa7464633ce1f1 827 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 177 823 2.4E-105 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS12225 a3247c72cefb267eb4fa7464633ce1f1 827 SUPERFAMILY SSF56935 133 823 5.49E-117 T 29-03-2018 CVS48_RS12225 a3247c72cefb267eb4fa7464633ce1f1 827 Gene3D G3DSA:2.40.170.20 288 824 1.7E-77 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12425 0d24a3972a752c3c8398696597230dec 710 Gene3D G3DSA:2.170.130.10 22 161 3.5E-25 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS12425 0d24a3972a752c3c8398696597230dec 710 Gene3D G3DSA:2.40.170.20 167 710 3.5E-76 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12425 0d24a3972a752c3c8398696597230dec 710 SUPERFAMILY SSF56935 24 707 2.75E-117 T 29-03-2018 CVS48_RS12425 0d24a3972a752c3c8398696597230dec 710 Pfam PF00593 TonB dependent receptor 240 705 2.0E-49 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12425 0d24a3972a752c3c8398696597230dec 710 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 156 5.6E-19 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS03800 c3e152993c6eaf476c02097db358fdcd 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 131 1.8E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS03800 c3e152993c6eaf476c02097db358fdcd 143 SUPERFAMILY SSF54593 10 140 1.34E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS03800 c3e152993c6eaf476c02097db358fdcd 143 Gene3D G3DSA:3.10.180.10 2 134 3.7E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS16510 d390d9809cae69f86583600efad21237 290 Gene3D G3DSA:1.10.3470.10 4 281 5.2E-43 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS16510 d390d9809cae69f86583600efad21237 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 278 1.5E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS17745 eaf01c564d6f5c760303f689760bf4e0 306 SUPERFAMILY SSF53850 89 294 1.5E-25 T 29-03-2018 CVS48_RS17745 eaf01c564d6f5c760303f689760bf4e0 306 SUPERFAMILY SSF46785 4 88 1.05E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17745 eaf01c564d6f5c760303f689760bf4e0 306 Gene3D G3DSA:3.40.190.10 196 268 4.5E-6 T 29-03-2018 CVS48_RS17745 eaf01c564d6f5c760303f689760bf4e0 306 Pfam PF03466 LysR substrate binding domain 96 295 9.1E-16 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17745 eaf01c564d6f5c760303f689760bf4e0 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 3.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17745 eaf01c564d6f5c760303f689760bf4e0 306 Gene3D G3DSA:3.40.190.10 88 195 1.3E-5 T 29-03-2018 CVS48_RS17745 eaf01c564d6f5c760303f689760bf4e0 306 Gene3D G3DSA:1.10.10.10 2 87 1.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11825 b03a9f06dbcd5bff54c5ade9a4cda976 217 PIRSF PIRSF006324 6 213 1.2E-58 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS11825 b03a9f06dbcd5bff54c5ade9a4cda976 217 Pfam PF01810 LysE type translocator 20 210 7.8E-33 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS10110 3c5a069d59dfe3154942ad0868117967 531 Gene3D G3DSA:3.40.50.980 31 192 1.6E-35 T 29-03-2018 CVS48_RS10110 3c5a069d59dfe3154942ad0868117967 531 Gene3D G3DSA:3.30.300.30 411 517 1.3E-27 T 29-03-2018 CVS48_RS10110 3c5a069d59dfe3154942ad0868117967 531 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 501 4.3E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS10110 3c5a069d59dfe3154942ad0868117967 531 Gene3D G3DSA:2.30.38.10 384 410 7.4E-4 T 29-03-2018 CVS48_RS10110 3c5a069d59dfe3154942ad0868117967 531 Gene3D G3DSA:3.40.50.980 193 346 4.2E-35 T 29-03-2018 CVS48_RS10110 3c5a069d59dfe3154942ad0868117967 531 SUPERFAMILY SSF56801 30 513 1.09E-125 T 29-03-2018 CVS48_RS10110 3c5a069d59dfe3154942ad0868117967 531 Pfam PF00501 AMP-binding enzyme 46 381 2.1E-59 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS10110 3c5a069d59dfe3154942ad0868117967 531 Gene3D G3DSA:2.30.38.10 347 383 1.9E-5 T 29-03-2018 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 SMART SM00382 225 370 2.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 SMART SM00382 634 776 4.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 638 656 1.2E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 730 1.2E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 745 759 1.2E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 1.2E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 SUPERFAMILY SSF81923 11 128 4.05E-18 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 321 333 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 23 75 7.1E-5 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 114 130 2.4 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 SMART SM01086 808 901 5.8E-11 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 SUPERFAMILY SSF52540 186 518 8.24E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 12 891 0.0 T 29-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 809 882 5.6E-10 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Gene3D G3DSA:1.10.1780.10 2 163 9.5E-28 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 SUPERFAMILY SSF52540 583 875 2.53E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Gene3D G3DSA:3.40.50.300 589 807 3.9E-41 T 29-03-2018 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Gene3D G3DSA:1.10.8.60 809 902 7.8E-10 T 29-03-2018 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Gene3D G3DSA:1.10.8.60 371 584 5.7E-36 T 29-03-2018 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Pfam PF07724 AAA domain (Cdc48 subfamily) 633 802 2.1E-43 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 230 342 2.3E-9 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS02085 14e6923d8d18bac5094c90c0ac83e5ea 904 Gene3D G3DSA:3.40.50.300 185 369 3.0E-23 T 29-03-2018 CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 Gene3D G3DSA:3.40.50.720 1 245 4.6E-75 T 29-03-2018 CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 3.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 6.4E-69 T 29-03-2018 CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 1.4E-4 T 29-03-2018 CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 SUPERFAMILY SSF51735 5 244 1.35E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 6.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 6.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09320 ade553d1899407f0e864e8aaa524697d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23585 f4286300b821195c924210c1ba9541c8 332 Pfam PF00482 Type II secretion system (T2SS), protein F 187 313 1.3E-12 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS17030 8850b9a94acff0fd48e73e09013a090b 142 Gene3D G3DSA:1.20.120.340 10 135 2.5E-33 T 29-03-2018 CVS48_RS17030 8850b9a94acff0fd48e73e09013a090b 142 Pfam PF02561 Flagellar protein FliS 23 131 3.4E-32 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CVS48_RS17030 8850b9a94acff0fd48e73e09013a090b 142 TIGRFAM TIGR00208 fliS: flagellar protein FliS 16 134 1.1E-23 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CVS48_RS17030 8850b9a94acff0fd48e73e09013a090b 142 PIRSF PIRSF039090 10 139 6.7E-32 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CVS48_RS17030 8850b9a94acff0fd48e73e09013a090b 142 SUPERFAMILY SSF101116 16 131 2.35E-31 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CVS48_RS25575 236e2965cb325fd461074c1c8b67cde3 338 PIRSF PIRSF017082 7 338 1.0E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25575 236e2965cb325fd461074c1c8b67cde3 338 Gene3D G3DSA:3.40.190.10 137 246 2.4E-11 T 29-03-2018 CVS48_RS25575 236e2965cb325fd461074c1c8b67cde3 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 333 5.2E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25575 236e2965cb325fd461074c1c8b67cde3 338 SUPERFAMILY SSF53850 58 286 1.47E-12 T 29-03-2018 CVS48_RS07815 2c9d5fd4d801e7902597606707f2f68f 183 SUPERFAMILY SSF53271 7 178 7.08E-53 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CVS48_RS07815 2c9d5fd4d801e7902597606707f2f68f 183 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 10 178 1.1E-67 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CVS48_RS07815 2c9d5fd4d801e7902597606707f2f68f 183 Pfam PF00156 Phosphoribosyl transferase domain 50 157 2.3E-17 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CVS48_RS07815 2c9d5fd4d801e7902597606707f2f68f 183 Gene3D G3DSA:3.40.50.2020 2 180 2.2E-43 T 29-03-2018 CVS48_RS07815 2c9d5fd4d801e7902597606707f2f68f 183 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 9 178 37.058 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CVS48_RS04075 df628f6bbf3e2f8b56d40583cd0c9713 357 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CVS48_RS04075 df628f6bbf3e2f8b56d40583cd0c9713 357 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CVS48_RS04075 df628f6bbf3e2f8b56d40583cd0c9713 357 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 11 350 1.8E-126 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CVS48_RS04075 df628f6bbf3e2f8b56d40583cd0c9713 357 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 350 1.5E-130 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CVS48_RS04075 df628f6bbf3e2f8b56d40583cd0c9713 357 Gene3D G3DSA:3.20.20.210 2 357 3.9E-102 T 29-03-2018 CVS48_RS04075 df628f6bbf3e2f8b56d40583cd0c9713 357 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 352 48.449 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CVS48_RS04075 df628f6bbf3e2f8b56d40583cd0c9713 357 SUPERFAMILY SSF51726 5 354 1.74E-115 T 29-03-2018 CVS48_RS08265 b3e02030c06cf75021c598509bb9e561 492 SUPERFAMILY SSF111369 187 411 7.06E-24 T 29-03-2018 CVS48_RS08265 b3e02030c06cf75021c598509bb9e561 492 Gene3D G3DSA:1.20.1600.10 175 419 3.0E-18 T 29-03-2018 CVS48_RS08265 b3e02030c06cf75021c598509bb9e561 492 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 169 479 8.7E-47 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS08265 b3e02030c06cf75021c598509bb9e561 492 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 176 407 1.5E-42 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 Gene3D G3DSA:3.40.50.620 3 114 1.4E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 Gene3D G3DSA:3.40.50.620 115 232 6.4E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 252 1.2E-37 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 3.9E-13 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 204 3.9E-13 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 180 190 3.9E-13 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 3.9E-13 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 3.9E-13 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 3 277 6.9E-113 T 29-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 3 296 44.068 T 29-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 CVS48_RS05715 5178f81555474bfe9c2da45abdac8c02 296 SUPERFAMILY SSF52374 3 255 2.95E-79 T 29-03-2018 CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 Gene3D G3DSA:3.30.70.600 3 103 7.8E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 5.6E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 SUPERFAMILY SSF54999 5 101 5.49E-38 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.66 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 SMART SM01403 7 101 1.8E-56 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.4E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.4E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.4E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06340 21d2822f5ea1628a34d6d8705668527e 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.5E-46 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS28855 67ef3db5b127cf06300ba18892ec2632 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.7E-25 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS28855 67ef3db5b127cf06300ba18892ec2632 67 PIRSF PIRSF002599 1 67 1.8E-20 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CVS48_RS28855 67ef3db5b127cf06300ba18892ec2632 67 SMART SM00357 3 67 2.5E-25 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CVS48_RS28855 67ef3db5b127cf06300ba18892ec2632 67 SUPERFAMILY SSF50249 1 66 1.11E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS28855 67ef3db5b127cf06300ba18892ec2632 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CVS48_RS28855 67ef3db5b127cf06300ba18892ec2632 67 PRINTS PR00050 Cold shock protein signature 40 58 9.6E-12 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS28855 67ef3db5b127cf06300ba18892ec2632 67 PRINTS PR00050 Cold shock protein signature 25 34 9.6E-12 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS28855 67ef3db5b127cf06300ba18892ec2632 67 PRINTS PR00050 Cold shock protein signature 4 19 9.6E-12 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS28855 67ef3db5b127cf06300ba18892ec2632 67 Gene3D G3DSA:2.40.50.140 1 67 1.2E-23 T 29-03-2018 CVS48_RS13205 e0341b7ab3cd96a9c1a160c7f8e00e42 491 Pfam PF01384 Phosphate transporter family 30 478 1.5E-83 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CVS48_RS12485 97608c1168ea6c953329ed7e32cbb7ca 226 SMART SM00257 24 68 2.8E-15 T 29-03-2018 IPR018392 LysM domain CVS48_RS12485 97608c1168ea6c953329ed7e32cbb7ca 226 SUPERFAMILY SSF51261 24 221 2.04E-45 T 29-03-2018 IPR011055 Duplicated hybrid motif CVS48_RS12485 97608c1168ea6c953329ed7e32cbb7ca 226 Pfam PF01476 LysM domain 25 67 1.2E-14 T 29-03-2018 IPR018392 LysM domain CVS48_RS12485 97608c1168ea6c953329ed7e32cbb7ca 226 Pfam PF01551 Peptidase family M23 126 219 2.3E-27 T 29-03-2018 IPR016047 Peptidase M23 CVS48_RS12485 97608c1168ea6c953329ed7e32cbb7ca 226 Gene3D G3DSA:3.10.350.10 17 77 8.2E-19 T 29-03-2018 CVS48_RS12485 97608c1168ea6c953329ed7e32cbb7ca 226 Gene3D G3DSA:2.70.70.10 78 225 5.3E-31 T 29-03-2018 CVS48_RS11170 772c1716efcb69268ff9aa29e423831a 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 267 5.3E-57 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS11170 772c1716efcb69268ff9aa29e423831a 275 Gene3D G3DSA:3.90.226.10 7 274 2.9E-70 T 29-03-2018 CVS48_RS11170 772c1716efcb69268ff9aa29e423831a 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 111 131 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS11170 772c1716efcb69268ff9aa29e423831a 275 SUPERFAMILY SSF52096 12 270 2.09E-73 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS05460 f2a0269baca96663f5fe24903aa9b4b3 210 Pfam PF01323 DSBA-like thioredoxin domain 50 184 3.7E-15 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CVS48_RS05460 f2a0269baca96663f5fe24903aa9b4b3 210 Gene3D G3DSA:3.40.30.10 11 207 1.1E-35 T 29-03-2018 CVS48_RS05460 f2a0269baca96663f5fe24903aa9b4b3 210 ProSitePatterns PS00194 Thioredoxin family active site. 50 68 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CVS48_RS05460 f2a0269baca96663f5fe24903aa9b4b3 210 SUPERFAMILY SSF52833 39 196 5.13E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS05460 f2a0269baca96663f5fe24903aa9b4b3 210 PIRSF PIRSF001488 4 210 4.2E-59 T 29-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL CVS48_RS20750 3eb52ecb3461641657f97f20967d5b66 131 SUPERFAMILY SSF88723 1 128 1.34E-16 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS20750 3eb52ecb3461641657f97f20967d5b66 131 Pfam PF01850 PIN domain 4 123 7.8E-8 T 29-03-2018 IPR002716 PIN domain CVS48_RS20750 3eb52ecb3461641657f97f20967d5b66 131 Gene3D G3DSA:3.40.50.1010 1 128 4.1E-13 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS23215 1213f92a52b46b8dfa26900dbb93c5b5 439 ProSitePatterns PS00161 Isocitrate lyase signature. 191 196 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CVS48_RS23215 1213f92a52b46b8dfa26900dbb93c5b5 439 Gene3D G3DSA:3.20.20.60 1 413 5.3E-150 T 29-03-2018 CVS48_RS23215 1213f92a52b46b8dfa26900dbb93c5b5 439 Pfam PF00463 Isocitrate lyase family 254 430 8.9E-46 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CVS48_RS23215 1213f92a52b46b8dfa26900dbb93c5b5 439 Pfam PF00463 Isocitrate lyase family 13 253 4.8E-58 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CVS48_RS23215 1213f92a52b46b8dfa26900dbb93c5b5 439 SUPERFAMILY SSF51621 6 430 1.17E-157 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS23215 1213f92a52b46b8dfa26900dbb93c5b5 439 PIRSF PIRSF001362 1 433 1.1E-237 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CVS48_RS23215 1213f92a52b46b8dfa26900dbb93c5b5 439 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 253 5.8E-111 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CVS48_RS07745 f29b15b63c457365874f586b5156b035 151 Gene3D G3DSA:3.40.930.10 1 148 8.2E-37 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CVS48_RS07745 f29b15b63c457365874f586b5156b035 151 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CVS48_RS07745 f29b15b63c457365874f586b5156b035 151 SUPERFAMILY SSF55804 1 146 4.32E-40 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CVS48_RS07745 f29b15b63c457365874f586b5156b035 151 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 146 1.9E-30 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 72 1.6E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 Gene3D G3DSA:3.40.190.10 98 190 1.1E-10 T 29-03-2018 CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 SUPERFAMILY SSF53850 101 308 2.9E-26 T 29-03-2018 CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 1.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 1.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 1.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 Gene3D G3DSA:1.10.10.10 7 94 2.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 SUPERFAMILY SSF46785 11 121 9.52E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 Gene3D G3DSA:3.40.190.10 191 277 2.7E-11 T 29-03-2018 CVS48_RS13280 202bb06a95c3c6129224c7ab7f9885fa 325 Pfam PF03466 LysR substrate binding domain 98 307 1.5E-23 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS05230 187f223860d8bf5b7d9fe137e5e418eb 378 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 363 7.9E-54 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS05230 187f223860d8bf5b7d9fe137e5e418eb 378 Gene3D G3DSA:1.10.3470.10 51 373 2.7E-24 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS11470 d0444adb27d72a115458d741b54ca3bf 436 Gene3D G3DSA:1.20.1250.20 13 229 5.7E-24 T 29-03-2018 CVS48_RS11470 d0444adb27d72a115458d741b54ca3bf 436 Pfam PF00083 Sugar (and other) transporter 26 230 2.5E-20 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS11470 d0444adb27d72a115458d741b54ca3bf 436 SUPERFAMILY SSF103473 17 434 2.09E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS11470 d0444adb27d72a115458d741b54ca3bf 436 Gene3D G3DSA:1.20.1250.20 230 436 1.4E-19 T 29-03-2018 CVS48_RS00205 6da21ddd27cfdf0526072ca0cfed2706 432 SUPERFAMILY SSF51419 52 283 1.41E-29 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS00205 6da21ddd27cfdf0526072ca0cfed2706 432 Gene3D G3DSA:3.20.20.10 51 342 5.5E-37 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS00205 6da21ddd27cfdf0526072ca0cfed2706 432 Pfam PF14031 Putative serine dehydratase domain 310 418 3.5E-16 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CVS48_RS00205 6da21ddd27cfdf0526072ca0cfed2706 432 SMART SM01119 310 419 9.2E-36 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CVS48_RS00205 6da21ddd27cfdf0526072ca0cfed2706 432 Pfam PF01168 Alanine racemase, N-terminal domain 52 252 2.4E-11 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS00220 c3cf0d2e37fdfab12778bc51062005c3 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 289 1.7E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS00220 c3cf0d2e37fdfab12778bc51062005c3 291 SUPERFAMILY SSF161098 83 288 3.92E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS00220 c3cf0d2e37fdfab12778bc51062005c3 291 Gene3D G3DSA:1.10.3720.10 27 289 4.1E-39 T 29-03-2018 CVS48_RS00220 c3cf0d2e37fdfab12778bc51062005c3 291 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 65 8.5E-8 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS28495 026cba6eb9113dfb722d5eb0b9b214f8 283 SUPERFAMILY SSF56752 4 276 2.75E-70 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CVS48_RS28495 026cba6eb9113dfb722d5eb0b9b214f8 283 Gene3D G3DSA:3.20.10.10 124 277 8.2E-34 T 29-03-2018 CVS48_RS28495 026cba6eb9113dfb722d5eb0b9b214f8 283 Pfam PF01063 Amino-transferase class IV 32 252 9.1E-40 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CVS48_RS28495 026cba6eb9113dfb722d5eb0b9b214f8 283 Gene3D G3DSA:3.30.470.10 1 122 1.0E-22 T 29-03-2018 CVS48_RS03070 49af70c1681a076451419a4ec9538ef6 270 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS03070 49af70c1681a076451419a4ec9538ef6 270 Pfam PF00005 ABC transporter 36 175 1.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS03070 49af70c1681a076451419a4ec9538ef6 270 SUPERFAMILY SSF52540 17 223 3.39E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03070 49af70c1681a076451419a4ec9538ef6 270 Gene3D G3DSA:3.40.50.300 13 235 3.6E-64 T 29-03-2018 CVS48_RS03070 49af70c1681a076451419a4ec9538ef6 270 SMART SM00382 45 226 4.8E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 SUPERFAMILY SSF51905 272 383 1.12E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 SUPERFAMILY SSF51905 7 178 1.12E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 Gene3D G3DSA:3.50.50.60 5 307 1.6E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 Gene3D G3DSA:3.30.9.10 308 363 3.0E-13 T 29-03-2018 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 7.1E-33 T 29-03-2018 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 7.1E-33 T 29-03-2018 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 7.1E-33 T 29-03-2018 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 7.1E-33 T 29-03-2018 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 336 7.1E-33 T 29-03-2018 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 Pfam PF01494 FAD binding domain 7 346 8.9E-60 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS02035 a8b09103cb785a6804387df16c491910 541 Gene3D G3DSA:3.40.30.20 439 537 2.1E-6 T 29-03-2018 CVS48_RS01400 577baa3a74fdf4b6e2eb41991cf38442 387 Pfam PF01494 FAD binding domain 174 314 1.3E-10 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS01400 577baa3a74fdf4b6e2eb41991cf38442 387 SUPERFAMILY SSF51905 6 178 5.18E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01400 577baa3a74fdf4b6e2eb41991cf38442 387 SUPERFAMILY SSF51905 270 382 5.18E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01400 577baa3a74fdf4b6e2eb41991cf38442 387 Gene3D G3DSA:3.50.50.60 4 355 5.5E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01400 577baa3a74fdf4b6e2eb41991cf38442 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 4.3E-13 T 29-03-2018 CVS48_RS01400 577baa3a74fdf4b6e2eb41991cf38442 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 4.3E-13 T 29-03-2018 CVS48_RS01400 577baa3a74fdf4b6e2eb41991cf38442 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 4.3E-13 T 29-03-2018 CVS48_RS01400 577baa3a74fdf4b6e2eb41991cf38442 387 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 382 4.3E-84 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 CVS48_RS01400 577baa3a74fdf4b6e2eb41991cf38442 387 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 288 301 - T 29-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 CVS48_RS12235 da1b67de463826236da78e73bdbeeb40 172 SUPERFAMILY SSF88946 10 97 1.65E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12235 da1b67de463826236da78e73bdbeeb40 172 Pfam PF04542 Sigma-70 region 2 15 80 9.6E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12235 da1b67de463826236da78e73bdbeeb40 172 SUPERFAMILY SSF88659 106 163 4.58E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12235 da1b67de463826236da78e73bdbeeb40 172 Pfam PF08281 Sigma-70, region 4 111 163 5.9E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12235 da1b67de463826236da78e73bdbeeb40 172 Gene3D G3DSA:1.10.1740.10 1 64 2.8E-13 T 29-03-2018 CVS48_RS12235 da1b67de463826236da78e73bdbeeb40 172 Gene3D G3DSA:1.10.10.10 65 164 1.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12235 da1b67de463826236da78e73bdbeeb40 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 162 1.5E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS03845 4adaa687ee087b544ce455b7119b3bdd 335 Gene3D G3DSA:1.10.1530.10 2 77 9.6E-22 T 29-03-2018 CVS48_RS03845 4adaa687ee087b544ce455b7119b3bdd 335 Gene3D G3DSA:3.30.1370.60 78 289 8.3E-80 T 29-03-2018 CVS48_RS03845 4adaa687ee087b544ce455b7119b3bdd 335 Pfam PF02615 Malate/L-lactate dehydrogenase 6 328 2.7E-105 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CVS48_RS03845 4adaa687ee087b544ce455b7119b3bdd 335 SUPERFAMILY SSF89733 3 332 4.45E-104 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CVS48_RS03845 4adaa687ee087b544ce455b7119b3bdd 335 Gene3D G3DSA:1.10.1530.10 290 322 0.45 T 29-03-2018 CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 SUPERFAMILY SSF53850 91 301 6.21E-34 T 29-03-2018 CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 Gene3D G3DSA:3.40.190.10 182 271 3.1E-16 T 29-03-2018 CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 Pfam PF03466 LysR substrate binding domain 93 296 5.7E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.1E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 Gene3D G3DSA:3.40.190.10 93 181 4.3E-18 T 29-03-2018 CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 SUPERFAMILY SSF46785 4 115 2.61E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10040 6b600140feab0bc112621d3c52c615e7 325 Gene3D G3DSA:1.10.10.10 2 91 2.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10385 2e75af4a0e8015278ef6b66cc17373cd 421 Gene3D G3DSA:3.30.70.20 35 107 2.4E-4 T 29-03-2018 CVS48_RS10385 2e75af4a0e8015278ef6b66cc17373cd 421 SUPERFAMILY SSF54862 66 117 2.76E-6 T 29-03-2018 CVS48_RS10385 2e75af4a0e8015278ef6b66cc17373cd 421 TIGRFAM TIGR02484 CitB: CitB domain protein 58 416 6.9E-127 T 29-03-2018 IPR012830 Citrate utilization protein B CVS48_RS10385 2e75af4a0e8015278ef6b66cc17373cd 421 Gene3D G3DSA:1.20.950.20 197 405 6.1E-33 T 29-03-2018 CVS48_RS10385 2e75af4a0e8015278ef6b66cc17373cd 421 SUPERFAMILY SSF103501 200 412 1.03E-31 T 29-03-2018 IPR023234 NarG-like domain CVS48_RS10385 2e75af4a0e8015278ef6b66cc17373cd 421 Gene3D G3DSA:3.30.70.20 108 158 0.011 T 29-03-2018 CVS48_RS06805 818804b029310172b50ba2b23085e786 932 Pfam PF07581 The GLUG motif 823 853 2.0E-5 T 29-03-2018 IPR011493 GLUG CVS48_RS06805 818804b029310172b50ba2b23085e786 932 Pfam PF07581 The GLUG motif 790 814 3.9E-4 T 29-03-2018 IPR011493 GLUG CVS48_RS06805 818804b029310172b50ba2b23085e786 932 Pfam PF07581 The GLUG motif 653 675 0.001 T 29-03-2018 IPR011493 GLUG CVS48_RS06805 818804b029310172b50ba2b23085e786 932 SMART SM00912 43 156 3.3E-37 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06805 818804b029310172b50ba2b23085e786 932 SUPERFAMILY SSF51126 46 335 6.59E-43 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS06805 818804b029310172b50ba2b23085e786 932 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 78 152 2.1E-24 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06805 818804b029310172b50ba2b23085e786 932 Pfam PF05860 haemagglutination activity domain 43 156 4.7E-24 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS06805 818804b029310172b50ba2b23085e786 932 Gene3D G3DSA:2.160.20.10 316 389 2.1E-5 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS06805 818804b029310172b50ba2b23085e786 932 Gene3D G3DSA:2.160.20.10 38 315 1.6E-54 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS22370 d2ece34782a5c6f1550894ab9d6b73ab 309 Gene3D G3DSA:1.10.3470.10 1 298 1.8E-51 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS22370 d2ece34782a5c6f1550894ab9d6b73ab 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 3.8E-46 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS11880 219d4d1de37ff885b765c46db3458eef 575 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 36 243 1.3E-68 T 29-03-2018 IPR027788 Alpha/beta-hydrolase, N-terminal domain CVS48_RS11880 219d4d1de37ff885b765c46db3458eef 575 Pfam PF10081 Alpha/beta-hydrolase family 260 546 1.1E-113 T 29-03-2018 IPR027787 Alpha/beta-hydrolase, catalytic domain CVS48_RS11880 219d4d1de37ff885b765c46db3458eef 575 PIRSF PIRSF007542 2 563 2.5E-246 T 29-03-2018 IPR012037 Alpha/beta-hydrolase family CVS48_RS21095 ab4fb209693cb515b479ed88b48ea497 210 SMART SM00903 19 171 1.3E-21 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS21095 ab4fb209693cb515b479ed88b48ea497 210 Gene3D G3DSA:2.30.110.10 9 187 2.4E-45 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS21095 ab4fb209693cb515b479ed88b48ea497 210 SUPERFAMILY SSF50475 1 191 1.28E-44 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS21095 ab4fb209693cb515b479ed88b48ea497 210 Pfam PF01613 Flavin reductase like domain 22 162 4.9E-17 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS15375 4c206a28c825507fe1500a231218052a 642 Gene3D G3DSA:2.140.10.30 30 150 8.4E-7 T 29-03-2018 CVS48_RS15375 4c206a28c825507fe1500a231218052a 642 SUPERFAMILY SSF50993 67 371 2.59E-14 T 29-03-2018 CVS48_RS15375 4c206a28c825507fe1500a231218052a 642 Gene3D G3DSA:2.130.10.120 154 374 2.1E-21 T 29-03-2018 CVS48_RS15375 4c206a28c825507fe1500a231218052a 642 SUPERFAMILY SSF53474 385 641 2.58E-73 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS15375 4c206a28c825507fe1500a231218052a 642 Pfam PF00326 Prolyl oligopeptidase family 430 641 1.4E-46 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CVS48_RS15375 4c206a28c825507fe1500a231218052a 642 Gene3D G3DSA:3.40.50.1820 375 642 1.1E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 PIRSF PIRSF016578 12 82 4.2E-7 T 29-03-2018 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 PIRSF PIRSF016578 137 384 6.0E-11 T 29-03-2018 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 217 8.8E-29 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 Gene3D G3DSA:1.20.140.10 217 385 1.1E-55 T 29-03-2018 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 117 7.3E-26 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 SUPERFAMILY SSF47203 228 381 2.09E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 377 5.8E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 Gene3D G3DSA:2.40.110.10 120 216 5.3E-42 T 29-03-2018 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 Gene3D G3DSA:1.10.540.10 4 118 5.1E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 SUPERFAMILY SSF56645 9 241 4.06E-79 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS09775 9ea3de932c3e9534623feae717a1827e 388 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS10080 7c171cf973c9534b12ac1f09aa8d584e 248 SUPERFAMILY SSF48008 101 233 1.15E-6 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS10080 7c171cf973c9534b12ac1f09aa8d584e 248 SMART SM00345 20 81 1.4E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10080 7c171cf973c9534b12ac1f09aa8d584e 248 Gene3D G3DSA:1.20.120.530 98 239 4.0E-11 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS10080 7c171cf973c9534b12ac1f09aa8d584e 248 Gene3D G3DSA:1.10.10.10 5 95 2.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10080 7c171cf973c9534b12ac1f09aa8d584e 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 75 5.6E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10080 7c171cf973c9534b12ac1f09aa8d584e 248 SUPERFAMILY SSF46785 11 91 3.11E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24190 65d3b88b00fbb6871a5f840a553f8a73 184 SUPERFAMILY SSF52218 5 175 1.59E-44 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS24190 65d3b88b00fbb6871a5f840a553f8a73 184 Gene3D G3DSA:3.40.50.360 2 184 2.8E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS24190 65d3b88b00fbb6871a5f840a553f8a73 184 Pfam PF03358 NADPH-dependent FMN reductase 5 147 3.1E-34 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CVS48_RS23740 7a26d5c718751d31685dfd1892480e76 753 Gene3D G3DSA:3.40.50.300 549 742 3.1E-28 T 29-03-2018 CVS48_RS23740 7a26d5c718751d31685dfd1892480e76 753 SUPERFAMILY SSF52540 550 725 1.12E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23740 7a26d5c718751d31685dfd1892480e76 753 Pfam PF02706 Chain length determinant protein 25 110 5.0E-12 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CVS48_RS23740 7a26d5c718751d31685dfd1892480e76 753 Pfam PF13807 G-rich domain on putative tyrosine kinase 391 472 5.0E-30 T 29-03-2018 IPR032807 Tyrosine kinase, G-rich domain CVS48_RS23740 7a26d5c718751d31685dfd1892480e76 753 Gene3D G3DSA:3.30.1890.10 47 447 3.0E-60 T 29-03-2018 CVS48_RS23740 7a26d5c718751d31685dfd1892480e76 753 TIGRFAM TIGR01005 eps_transp_fam: exopolysaccharide transport protein family 21 745 1.1E-138 T 29-03-2018 IPR005700 Exopolysaccharide transport protein GO:0006859|GO:0015542 CVS48_RS23740 7a26d5c718751d31685dfd1892480e76 753 Pfam PF13614 AAA domain 559 675 1.1E-7 T 29-03-2018 IPR025669 AAA domain CVS48_RS13535 84f86a2d2c17f8398fc2242bf949d8b8 475 Gene3D G3DSA:1.20.1260.10 97 454 5.9E-84 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS13535 84f86a2d2c17f8398fc2242bf949d8b8 475 SUPERFAMILY SSF47240 107 331 1.95E-48 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS13535 84f86a2d2c17f8398fc2242bf949d8b8 475 TIGRFAM TIGR03225 benzo_boxB: benzoyl-CoA oxygenase, B subunit 4 474 7.3E-270 T 29-03-2018 IPR017635 Benzoyl-CoA oxygenase, B subunit KEGG: 00361+1.14.13.20|MetaCyc: PWY-1361|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CVS48_RS12735 b3c2f139cc2e8dc00fb0dc993872ccdb 149 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 125 141 - T 29-03-2018 IPR028871 Blue (type 1) copper protein, binding site CVS48_RS12735 b3c2f139cc2e8dc00fb0dc993872ccdb 149 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 27 145 2.0E-58 T 29-03-2018 CVS48_RS12735 b3c2f139cc2e8dc00fb0dc993872ccdb 149 TIGRFAM TIGR02695 azurin: azurin 23 147 2.1E-62 T 29-03-2018 IPR014068 Azurin CVS48_RS12735 b3c2f139cc2e8dc00fb0dc993872ccdb 149 Gene3D G3DSA:2.60.40.420 21 147 3.6E-12 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS12735 b3c2f139cc2e8dc00fb0dc993872ccdb 149 SUPERFAMILY SSF49503 21 147 4.51E-47 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS12735 b3c2f139cc2e8dc00fb0dc993872ccdb 149 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 21 147 7.6E-32 T 29-03-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 CVS48_RS03140 25c90fa7564b4888e497cb63753e81ee 375 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 123 326 2.7E-14 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CVS48_RS03140 25c90fa7564b4888e497cb63753e81ee 375 PIRSF PIRSF016636 33 374 1.0E-73 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CVS48_RS23925 f70d3e9a2c68cb2e52f247ccc8344074 200 SUPERFAMILY SSF46689 3 83 5.49E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS23925 f70d3e9a2c68cb2e52f247ccc8344074 200 Gene3D G3DSA:1.10.357.10 65 200 1.0E-12 T 29-03-2018 CVS48_RS23925 f70d3e9a2c68cb2e52f247ccc8344074 200 SUPERFAMILY SSF48498 90 195 8.9E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS23925 f70d3e9a2c68cb2e52f247ccc8344074 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.3E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS23925 f70d3e9a2c68cb2e52f247ccc8344074 200 Gene3D G3DSA:1.10.10.60 2 64 5.7E-19 T 29-03-2018 CVS48_RS23925 f70d3e9a2c68cb2e52f247ccc8344074 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS23925 f70d3e9a2c68cb2e52f247ccc8344074 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS01615 ce12eb1645ae957cd475112226a18bbf 346 Gene3D G3DSA:1.10.3470.10 3 340 3.3E-25 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS01615 ce12eb1645ae957cd475112226a18bbf 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 115 330 1.2E-13 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS01615 ce12eb1645ae957cd475112226a18bbf 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 81 9.4E-6 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS07090 486b10292d2201f2113683db943f7ae7 332 SUPERFAMILY SSF51735 3 321 4.17E-90 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07090 486b10292d2201f2113683db943f7ae7 332 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 306 7.8E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07090 486b10292d2201f2113683db943f7ae7 332 TIGRFAM TIGR04180 EDH_00030: NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family 4 299 4.4E-159 T 29-03-2018 IPR026390 NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family CVS48_RS07090 486b10292d2201f2113683db943f7ae7 332 Gene3D G3DSA:3.90.25.10 191 330 2.9E-29 T 29-03-2018 CVS48_RS07090 486b10292d2201f2113683db943f7ae7 332 Gene3D G3DSA:3.40.50.720 2 190 3.4E-43 T 29-03-2018 CVS48_RS09965 7aacf21c08f6e29c00bfddf29aab3111 232 SUPERFAMILY SSF46785 162 219 1.84E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09965 7aacf21c08f6e29c00bfddf29aab3111 232 Gene3D G3DSA:1.10.10.10 134 226 8.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09965 7aacf21c08f6e29c00bfddf29aab3111 232 SUPERFAMILY SSF51206 2 132 9.69E-23 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CVS48_RS09965 7aacf21c08f6e29c00bfddf29aab3111 232 Pfam PF00027 Cyclic nucleotide-binding domain 26 112 5.4E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS09965 7aacf21c08f6e29c00bfddf29aab3111 232 Pfam PF13545 Crp-like helix-turn-helix domain 162 215 1.6E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CVS48_RS09965 7aacf21c08f6e29c00bfddf29aab3111 232 SMART SM00100 7 128 3.0E-6 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CVS48_RS09965 7aacf21c08f6e29c00bfddf29aab3111 232 Gene3D G3DSA:2.60.120.10 1 133 9.2E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS04395 41aaf5565afece6c071eca38c22f07c5 246 Pfam PF01925 Sulfite exporter TauE/SafE 16 236 1.8E-13 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CVS48_RS18715 ada95b1fa54e430f97adf2a9e233a9cc 179 Pfam PF04239 Protein of unknown function (DUF421) 98 165 1.7E-12 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CVS48_RS18715 ada95b1fa54e430f97adf2a9e233a9cc 179 Gene3D G3DSA:3.30.240.20 93 161 5.2E-16 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 SMART SM00387 332 444 5.8E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 SMART SM00388 223 289 5.4E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 Gene3D G3DSA:3.30.565.10 296 443 3.3E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 Gene3D G3DSA:1.10.287.130 213 285 2.0E-12 T 29-03-2018 CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 SUPERFAMILY SSF47384 206 289 2.16E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 289 2.0E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 9.5E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 398 9.5E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 9.5E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 440 7.3E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 8 438 9.9E-98 T 29-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 CVS48_RS08250 f5b41d9be416015519ca6890921a713d 444 SUPERFAMILY SSF55874 297 438 5.76E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 SUPERFAMILY SSF53328 89 284 4.97E-62 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 Gene3D G3DSA:3.40.50.170 88 284 5.7E-55 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 Pfam PF00551 Formyl transferase 89 265 2.3E-38 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 40 52 2.4E-56 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 235 257 2.4E-56 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 89 111 2.4E-56 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 111 138 2.4E-56 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 257 282 2.4E-56 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 8 34 2.4E-56 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 7 283 6.0E-105 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 PIRSF PIRSF036480 3 284 9.0E-112 T 29-03-2018 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 3 283 47.23 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 Gene3D G3DSA:3.30.70.260 1 87 1.4E-27 T 29-03-2018 CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 Pfam PF01842 ACT domain 6 54 1.6E-6 T 29-03-2018 IPR002912 ACT domain CVS48_RS01740 a72ba0e0d2606076c31161440e937765 284 SUPERFAMILY SSF55021 2 87 3.16E-19 T 29-03-2018 CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 Gene3D G3DSA:1.10.10.760 445 478 2.0E-16 T 29-03-2018 CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 Gene3D G3DSA:3.20.20.80 219 444 5.2E-32 T 29-03-2018 CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 Gene3D G3DSA:3.20.20.80 99 218 3.6E-30 T 29-03-2018 CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 Pfam PF00128 Alpha amylase, catalytic domain 125 213 2.3E-14 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 Pfam PF00128 Alpha amylase, catalytic domain 229 427 1.8E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 Gene3D G3DSA:2.60.40.1180 521 597 6.6E-17 T 29-03-2018 CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 SUPERFAMILY SSF81296 11 98 5.2E-13 T 29-03-2018 IPR014756 Immunoglobulin E-set CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 SMART SM00642 118 451 1.7E-11 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 Gene3D G3DSA:2.60.40.10 7 98 1.8E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 Pfam PF11941 Domain of unknown function (DUF3459) 498 594 2.1E-11 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 SUPERFAMILY SSF51445 93 508 2.11E-100 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 PIRSF PIRSF006337 7 584 3.0E-208 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CVS48_RS18375 6dcfc92645a5caca0684bd4cdaacb03f 599 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 20 555 1.7E-198 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CVS48_RS20740 7dc815fc298626933aa01a404a6835af 237 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 56 209 1.0E-35 T 29-03-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 CVS48_RS00370 ac84e7394c72ac8a562522bb93b6a8ad 293 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 41 187 1.2E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS00370 ac84e7394c72ac8a562522bb93b6a8ad 293 SUPERFAMILY SSF52540 19 249 9.38E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00370 ac84e7394c72ac8a562522bb93b6a8ad 293 SMART SM00382 37 195 1.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS00370 ac84e7394c72ac8a562522bb93b6a8ad 293 Gene3D G3DSA:3.40.50.300 16 223 5.8E-31 T 29-03-2018 CVS48_RS29010 77b01bfc320b3b200e85860ad7cd9144 808 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 791 808 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS29010 77b01bfc320b3b200e85860ad7cd9144 808 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 166 808 1.4E-102 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS29010 77b01bfc320b3b200e85860ad7cd9144 808 Pfam PF00593 TonB dependent receptor 359 806 8.5E-50 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS29010 77b01bfc320b3b200e85860ad7cd9144 808 Gene3D G3DSA:2.40.170.20 274 808 8.2E-81 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS29010 77b01bfc320b3b200e85860ad7cd9144 808 Gene3D G3DSA:2.170.130.10 120 273 7.4E-21 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS29010 77b01bfc320b3b200e85860ad7cd9144 808 SUPERFAMILY SSF56935 125 808 1.08E-121 T 29-03-2018 CVS48_RS29010 77b01bfc320b3b200e85860ad7cd9144 808 Pfam PF07715 TonB-dependent Receptor Plug Domain 164 262 5.1E-16 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS29010 77b01bfc320b3b200e85860ad7cd9144 808 SMART SM00965 67 118 1.4E-6 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS11155 c9ead254166d2067053f9de8dc09af5a 323 PIRSF PIRSF035875 5 308 7.0E-71 T 29-03-2018 IPR017039 Virulence factor BrkB CVS48_RS11155 c9ead254166d2067053f9de8dc09af5a 323 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 24 282 1.0E-21 T 29-03-2018 IPR017039 Virulence factor BrkB CVS48_RS11155 c9ead254166d2067053f9de8dc09af5a 323 Pfam PF03631 Virulence factor BrkB 28 285 9.2E-53 T 29-03-2018 IPR017039 Virulence factor BrkB CVS48_RS28135 55987a4e5e75ddc7d6392d914ee238b9 441 Gene3D G3DSA:3.90.1150.10 327 441 1.9E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS28135 55987a4e5e75ddc7d6392d914ee238b9 441 SUPERFAMILY SSF53383 12 437 6.72E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS28135 55987a4e5e75ddc7d6392d914ee238b9 441 Gene3D G3DSA:3.40.640.10 63 326 3.2E-71 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS28135 55987a4e5e75ddc7d6392d914ee238b9 441 PIRSF PIRSF000521 194 439 1.1E-14 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS28135 55987a4e5e75ddc7d6392d914ee238b9 441 PIRSF PIRSF000521 21 146 2.0E-6 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS28135 55987a4e5e75ddc7d6392d914ee238b9 441 Pfam PF00202 Aminotransferase class-III 22 437 1.6E-90 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS28135 55987a4e5e75ddc7d6392d914ee238b9 441 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS25175 0576ce02ca73213487edc050875f5143 192 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 5 192 6.5E-62 T 29-03-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CVS48_RS25175 0576ce02ca73213487edc050875f5143 192 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 40 68 - T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CVS48_RS25175 0576ce02ca73213487edc050875f5143 192 Pfam PF00775 Dioxygenase 36 146 1.3E-15 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CVS48_RS25175 0576ce02ca73213487edc050875f5143 192 Gene3D G3DSA:2.60.130.10 1 192 5.7E-51 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CVS48_RS25175 0576ce02ca73213487edc050875f5143 192 SUPERFAMILY SSF49482 2 192 1.03E-49 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CVS48_RS23725 1b582904b63bdea60cad0284188f00d6 355 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 332 2.4E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23725 1b582904b63bdea60cad0284188f00d6 355 Gene3D G3DSA:3.90.25.10 217 266 6.4E-9 T 29-03-2018 CVS48_RS23725 1b582904b63bdea60cad0284188f00d6 355 Gene3D G3DSA:3.90.25.10 267 346 5.1E-21 T 29-03-2018 CVS48_RS23725 1b582904b63bdea60cad0284188f00d6 355 SUPERFAMILY SSF51735 1 344 4.87E-89 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23725 1b582904b63bdea60cad0284188f00d6 355 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 8 342 4.4E-123 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CVS48_RS23725 1b582904b63bdea60cad0284188f00d6 355 PRINTS PR01713 Nucleotide sugar epimerase signature 304 321 5.9E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS23725 1b582904b63bdea60cad0284188f00d6 355 PRINTS PR01713 Nucleotide sugar epimerase signature 265 280 5.9E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS23725 1b582904b63bdea60cad0284188f00d6 355 PRINTS PR01713 Nucleotide sugar epimerase signature 240 255 5.9E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CVS48_RS23725 1b582904b63bdea60cad0284188f00d6 355 Gene3D G3DSA:3.40.50.720 4 216 2.4E-35 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 PRINTS PR01002 Flagellar protein FlgJ signature 185 203 4.8E-61 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 PRINTS PR01002 Flagellar protein FlgJ signature 161 184 4.8E-61 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 PRINTS PR01002 Flagellar protein FlgJ signature 205 226 4.8E-61 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 PRINTS PR01002 Flagellar protein FlgJ signature 227 248 4.8E-61 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 PRINTS PR01002 Flagellar protein FlgJ signature 60 80 4.8E-61 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 PRINTS PR01002 Flagellar protein FlgJ signature 35 58 4.8E-61 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 PRINTS PR01002 Flagellar protein FlgJ signature 249 270 4.8E-61 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 PRINTS PR01002 Flagellar protein FlgJ signature 271 290 4.8E-61 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 PRINTS PR01002 Flagellar protein FlgJ signature 291 309 4.8E-61 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 SMART SM00047 156 314 2.4E-46 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 17 308 9.9E-121 T 29-03-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 Pfam PF10135 Rod binding protein 57 103 5.0E-12 T 29-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 Gene3D G3DSA:1.10.530.10 157 312 2.8E-34 T 29-03-2018 CVS48_RS16900 db1d63b02be701e27d66764781d83e79 325 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 173 308 3.8E-20 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CVS48_RS02290 386b98021651fb3123902eeccd96f5ab 303 SUPERFAMILY SSF53850 95 301 3.37E-35 T 29-03-2018 CVS48_RS02290 386b98021651fb3123902eeccd96f5ab 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 9.8E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS02290 386b98021651fb3123902eeccd96f5ab 303 Pfam PF03466 LysR substrate binding domain 95 297 6.6E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS02290 386b98021651fb3123902eeccd96f5ab 303 Gene3D G3DSA:3.40.190.10 92 182 2.9E-18 T 29-03-2018 CVS48_RS02290 386b98021651fb3123902eeccd96f5ab 303 Gene3D G3DSA:1.10.10.10 1 91 1.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02290 386b98021651fb3123902eeccd96f5ab 303 SUPERFAMILY SSF46785 7 92 1.58E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02290 386b98021651fb3123902eeccd96f5ab 303 Gene3D G3DSA:3.40.190.10 183 270 2.8E-20 T 29-03-2018 CVS48_RS20380 ed6c3dab146809d0d148ed0bd725da8b 206 SUPERFAMILY SSF48498 99 199 5.04E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS20380 ed6c3dab146809d0d148ed0bd725da8b 206 Gene3D G3DSA:1.10.260.40 47 74 2.3E-12 T 29-03-2018 CVS48_RS20380 ed6c3dab146809d0d148ed0bd725da8b 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20380 ed6c3dab146809d0d148ed0bd725da8b 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20380 ed6c3dab146809d0d148ed0bd725da8b 206 SUPERFAMILY SSF46689 14 87 1.8E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS20380 ed6c3dab146809d0d148ed0bd725da8b 206 Gene3D G3DSA:1.10.357.10 75 203 1.2E-13 T 29-03-2018 CVS48_RS20380 ed6c3dab146809d0d148ed0bd725da8b 206 Gene3D G3DSA:1.10.10.60 1 46 2.0E-14 T 29-03-2018 CVS48_RS20380 ed6c3dab146809d0d148ed0bd725da8b 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 66 1.5E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS27050 8052f855b91229950c6d2db70ea3c929 376 SUPERFAMILY SSF51905 327 366 8.67E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27050 8052f855b91229950c6d2db70ea3c929 376 SUPERFAMILY SSF51905 3 213 8.67E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27050 8052f855b91229950c6d2db70ea3c929 376 Gene3D G3DSA:3.30.9.10 93 333 4.2E-10 T 29-03-2018 CVS48_RS27050 8052f855b91229950c6d2db70ea3c929 376 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 4 368 1.9E-134 T 29-03-2018 IPR017741 FAD-dependent oxidoreductase, HpnW CVS48_RS27050 8052f855b91229950c6d2db70ea3c929 376 Pfam PF01266 FAD dependent oxidoreductase 5 370 3.2E-33 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS27050 8052f855b91229950c6d2db70ea3c929 376 Gene3D G3DSA:3.50.50.60 1 92 7.2E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23235 7b2cc6286ae631785c91e25337ea5764 436 Pfam PF07690 Major Facilitator Superfamily 35 331 3.6E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS23235 7b2cc6286ae631785c91e25337ea5764 436 SUPERFAMILY SSF103473 11 416 2.35E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS23235 7b2cc6286ae631785c91e25337ea5764 436 Gene3D G3DSA:1.20.1250.20 11 213 1.2E-28 T 29-03-2018 CVS48_RS23235 7b2cc6286ae631785c91e25337ea5764 436 Gene3D G3DSA:1.20.1250.20 235 425 5.5E-20 T 29-03-2018 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1365 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 SMART SM00663 235 514 1.7E-172 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 11 1380 18.733 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 3.9E-85 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 SUPERFAMILY SSF64484 1133 1363 0.0 T 29-03-2018 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 SUPERFAMILY SSF64484 16 944 0.0 T 29-03-2018 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 1.3E-24 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 4.6E-18 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 4.3E-76 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Gene3D G3DSA:2.40.50.100 1110 1161 0.034 T 29-03-2018 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Gene3D G3DSA:2.40.50.100 1162 1212 2.5E-12 T 29-03-2018 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Gene3D G3DSA:2.40.50.100 1011 1038 0.046 T 29-03-2018 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Gene3D G3DSA:2.40.50.100 1039 1109 1.2E-11 T 29-03-2018 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Gene3D G3DSA:2.40.50.100 907 1010 2.0E-28 T 29-03-2018 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Pfam PF00623 RNA polymerase Rpb1, domain 2 395 485 1.8E-26 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 395 3.7E-8 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS06280 1fa43500ac03bde7cd4f8ca79962341f 1414 Gene3D G3DSA:2.40.40.20 346 488 6.6E-40 T 29-03-2018 CVS48_RS11290 22b8845c71624c574cbd98a4ef3987e2 348 PRINTS PR00111 Alpha/beta hydrolase fold signature 270 284 3.1E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11290 22b8845c71624c574cbd98a4ef3987e2 348 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 117 3.1E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11290 22b8845c71624c574cbd98a4ef3987e2 348 PRINTS PR00111 Alpha/beta hydrolase fold signature 147 160 3.1E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11290 22b8845c71624c574cbd98a4ef3987e2 348 SUPERFAMILY SSF53474 43 341 1.63E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11290 22b8845c71624c574cbd98a4ef3987e2 348 Pfam PF12697 Alpha/beta hydrolase family 78 335 6.5E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11290 22b8845c71624c574cbd98a4ef3987e2 348 Gene3D G3DSA:3.40.50.1820 30 343 2.9E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS06045 b9ce69f1991a3534ec84608bf611f823 123 Gene3D G3DSA:3.30.230.10 1 123 1.7E-24 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS06045 b9ce69f1991a3534ec84608bf611f823 123 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 61 75 - T 29-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CVS48_RS06045 b9ce69f1991a3534ec84608bf611f823 123 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 116 14.129 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CVS48_RS06045 b9ce69f1991a3534ec84608bf611f823 123 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 11 109 3.6E-11 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CVS48_RS06045 b9ce69f1991a3534ec84608bf611f823 123 SUPERFAMILY SSF54211 6 108 3.54E-18 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS06045 b9ce69f1991a3534ec84608bf611f823 123 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 44 97 1.0E-7 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CVS48_RS06045 b9ce69f1991a3534ec84608bf611f823 123 Pfam PF00825 Ribonuclease P 6 111 1.8E-19 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CVS48_RS11555 e91eaa807fdc179ade74021cb4445dc9 383 SUPERFAMILY SSF103473 10 368 1.14E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS11555 e91eaa807fdc179ade74021cb4445dc9 383 Gene3D G3DSA:1.20.1250.20 197 371 2.5E-12 T 29-03-2018 CVS48_RS11555 e91eaa807fdc179ade74021cb4445dc9 383 Gene3D G3DSA:1.20.1250.20 8 191 2.5E-22 T 29-03-2018 CVS48_RS11555 e91eaa807fdc179ade74021cb4445dc9 383 Pfam PF07690 Major Facilitator Superfamily 13 183 8.9E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS20960 a771cce49881fac06b98bdcdd1094a33 331 PIRSF PIRSF017082 4 330 1.6E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS20960 a771cce49881fac06b98bdcdd1094a33 331 SUPERFAMILY SSF53850 120 291 5.52E-15 T 29-03-2018 CVS48_RS20960 a771cce49881fac06b98bdcdd1094a33 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 327 1.6E-87 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS20960 a771cce49881fac06b98bdcdd1094a33 331 Gene3D G3DSA:3.40.190.10 131 241 1.3E-13 T 29-03-2018 CVS48_RS14735 9997546603a530e55e8ab55ae644dbbd 434 SMART SM00244 99 274 4.9E-24 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS14735 9997546603a530e55e8ab55ae644dbbd 434 Pfam PF12221 Bacterial membrane protein N terminal 8 58 6.4E-11 T 29-03-2018 IPR020980 Menbrane protein HflK, N-terminal CVS48_RS14735 9997546603a530e55e8ab55ae644dbbd 434 TIGRFAM TIGR01933 hflK: HflK protein 101 376 9.1E-89 T 29-03-2018 IPR010201 HflK GO:0016021 CVS48_RS14735 9997546603a530e55e8ab55ae644dbbd 434 Pfam PF01145 SPFH domain / Band 7 family 103 289 4.4E-27 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS14735 9997546603a530e55e8ab55ae644dbbd 434 SUPERFAMILY SSF117892 166 281 3.14E-20 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS16160 b0bec5a92ab317870a89e73ad1a66920 336 SUPERFAMILY SSF53067 11 148 2.85E-11 T 29-03-2018 CVS48_RS16160 b0bec5a92ab317870a89e73ad1a66920 336 Pfam PF12693 GspL periplasmic domain 181 321 2.3E-19 T 29-03-2018 IPR025691 GspL periplasmic domain CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 SUPERFAMILY SSF53092 172 299 4.45E-5 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 Gene3D G3DSA:3.40.350.10 154 303 2.7E-22 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 Pfam PF16189 Creatinase/Prolidase N-terminal domain 152 308 7.0E-34 T 29-03-2018 CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 Pfam PF00557 Metallopeptidase family M24 311 524 1.8E-43 T 29-03-2018 IPR000994 Peptidase M24 CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 SUPERFAMILY SSF53092 5 130 2.09E-10 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 Pfam PF01321 Creatinase/Prolidase N-terminal domain 7 133 5.1E-17 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 Gene3D G3DSA:3.90.230.10 304 556 1.7E-64 T 29-03-2018 CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 Gene3D G3DSA:3.40.350.10 1 148 1.7E-44 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 SUPERFAMILY SSF55920 305 562 1.44E-54 T 29-03-2018 IPR000994 Peptidase M24 CVS48_RS28020 cbff532b8e9ab2e1c6efa91b624a4bcd 598 Pfam PF16188 C-terminal region of peptidase_M24 536 594 1.2E-24 T 29-03-2018 IPR032416 Peptidase M24, C-terminal domain CVS48_RS25980 0e098dd44618532f031b54d68f6c669d 152 SMART SM00411 55 152 1.3E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS25980 0e098dd44618532f031b54d68f6c669d 152 SUPERFAMILY SSF47729 55 151 1.25E-13 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CVS48_RS25980 0e098dd44618532f031b54d68f6c669d 152 Gene3D G3DSA:4.10.520.10 49 152 6.1E-16 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CVS48_RS25980 0e098dd44618532f031b54d68f6c669d 152 Pfam PF00216 Bacterial DNA-binding protein 55 151 1.4E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 SUPERFAMILY SSF51735 6 252 2.1E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 2.2E-60 T 29-03-2018 CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 Gene3D G3DSA:3.40.50.720 48 256 4.9E-63 T 29-03-2018 CVS48_RS09980 32205c5a16e4637300aee31820fe34ba 258 Gene3D G3DSA:3.40.50.720 1 47 2.7E-9 T 29-03-2018 CVS48_RS11210 ffab6566f74a304217abe14bd3300db9 327 Gene3D G3DSA:3.40.190.10 127 257 1.2E-13 T 29-03-2018 CVS48_RS11210 ffab6566f74a304217abe14bd3300db9 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 323 3.6E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11210 ffab6566f74a304217abe14bd3300db9 327 PIRSF PIRSF017082 1 327 6.8E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11210 ffab6566f74a304217abe14bd3300db9 327 SUPERFAMILY SSF53850 115 289 1.15E-14 T 29-03-2018 CVS48_RS19825 13973235ce469f491f69290573aa8c72 213 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 13 208 20.901 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CVS48_RS19825 13973235ce469f491f69290573aa8c72 213 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 10 207 1.6E-61 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CVS48_RS19825 13973235ce469f491f69290573aa8c72 213 Pfam PF02660 Glycerol-3-phosphate acyltransferase 17 199 8.7E-52 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CVS48_RS19825 13973235ce469f491f69290573aa8c72 213 SMART SM01207 16 200 2.9E-85 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CVS48_RS26160 4dc294cf139d608afed9a76ff3cc325d 282 SUPERFAMILY SSF88713 22 99 9.64E-37 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CVS48_RS26160 4dc294cf139d608afed9a76ff3cc325d 282 SUPERFAMILY SSF88713 136 281 9.64E-37 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CVS48_RS26160 4dc294cf139d608afed9a76ff3cc325d 282 Pfam PF01522 Polysaccharide deacetylase 55 219 5.7E-33 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CVS48_RS26160 4dc294cf139d608afed9a76ff3cc325d 282 Gene3D G3DSA:3.20.20.370 14 281 2.3E-40 T 29-03-2018 CVS48_RS18225 dfd099efb7e3f975d6191f9dc33ddaa0 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS18225 dfd099efb7e3f975d6191f9dc33ddaa0 499 SUPERFAMILY SSF53720 15 496 2.88E-166 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS18225 dfd099efb7e3f975d6191f9dc33ddaa0 499 Pfam PF00171 Aldehyde dehydrogenase family 34 492 2.1E-170 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS18225 dfd099efb7e3f975d6191f9dc33ddaa0 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 266 273 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS18225 dfd099efb7e3f975d6191f9dc33ddaa0 499 Gene3D G3DSA:3.40.309.10 283 479 9.7E-70 T 29-03-2018 CVS48_RS18225 dfd099efb7e3f975d6191f9dc33ddaa0 499 Gene3D G3DSA:3.40.605.10 8 282 9.6E-97 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS08975 e8d392dc94a05fbf48a7dd33e4f72fb8 261 SUPERFAMILY SSF51658 1 257 5.53E-75 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CVS48_RS08975 e8d392dc94a05fbf48a7dd33e4f72fb8 261 Pfam PF01261 Xylose isomerase-like TIM barrel 22 218 7.0E-27 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CVS48_RS08975 e8d392dc94a05fbf48a7dd33e4f72fb8 261 Gene3D G3DSA:3.20.20.150 1 261 2.8E-50 T 29-03-2018 CVS48_RS08975 e8d392dc94a05fbf48a7dd33e4f72fb8 261 PIRSF PIRSF006241 1 261 4.3E-91 T 29-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 CVS48_RS06665 177f579ecdbd32e4d2d25d6fc94eb7ae 155 Pfam PF05638 Type VI secretion system effector, Hcp 1 129 7.1E-36 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS06665 177f579ecdbd32e4d2d25d6fc94eb7ae 155 Gene3D G3DSA:2.30.110.20 1 154 2.1E-43 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS06665 177f579ecdbd32e4d2d25d6fc94eb7ae 155 SUPERFAMILY SSF141452 1 153 1.01E-44 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS23790 80085c365ff9731418750d81a68ed92e 434 Pfam PF04932 O-Antigen ligase 190 331 2.7E-12 T 29-03-2018 IPR007016 O-antigen ligase-related CVS48_RS07395 9dcc340d7f6ed36af3ba249a7c1fca9b 295 Gene3D G3DSA:3.40.50.1820 4 293 6.1E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS07395 9dcc340d7f6ed36af3ba249a7c1fca9b 295 Pfam PF00561 alpha/beta hydrolase fold 28 132 3.0E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS07395 9dcc340d7f6ed36af3ba249a7c1fca9b 295 SUPERFAMILY SSF53474 6 292 8.86E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS24300 01d9ca86fca9346f030b61afe1eafec3 58 Pfam PF12244 Protein of unknown function (DUF3606) 4 56 6.8E-26 T 29-03-2018 IPR022037 Protein of unknown function DUF3606 CVS48_RS04130 4616d88bbbc10d70ecf7566766a1e81f 517 SUPERFAMILY SSF160935 263 515 4.58E-113 T 29-03-2018 CVS48_RS04130 4616d88bbbc10d70ecf7566766a1e81f 517 SUPERFAMILY SSF160935 46 232 4.58E-113 T 29-03-2018 CVS48_RS04130 4616d88bbbc10d70ecf7566766a1e81f 517 Pfam PF06863 Protein of unknown function (DUF1254) 96 226 1.2E-37 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 CVS48_RS04130 4616d88bbbc10d70ecf7566766a1e81f 517 Pfam PF06742 Protein of unknown function (DUF1214) 393 501 6.9E-35 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 CVS48_RS04130 4616d88bbbc10d70ecf7566766a1e81f 517 Gene3D G3DSA:2.60.120.600 345 516 5.3E-51 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 CVS48_RS04130 4616d88bbbc10d70ecf7566766a1e81f 517 Gene3D G3DSA:2.60.40.1610 96 242 5.3E-39 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 CVS48_RS19760 0f9e42a4f6fc6b3a95ef4ff9040bcff3 66 PRINTS PR00944 Copper ion binding protein signature 2 14 2.3E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CVS48_RS19760 0f9e42a4f6fc6b3a95ef4ff9040bcff3 66 PRINTS PR00944 Copper ion binding protein signature 50 63 2.3E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CVS48_RS19760 0f9e42a4f6fc6b3a95ef4ff9040bcff3 66 PRINTS PR00944 Copper ion binding protein signature 14 27 2.3E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CVS48_RS19760 0f9e42a4f6fc6b3a95ef4ff9040bcff3 66 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CVS48_RS19760 0f9e42a4f6fc6b3a95ef4ff9040bcff3 66 Gene3D G3DSA:3.30.70.100 1 66 1.4E-15 T 29-03-2018 CVS48_RS19760 0f9e42a4f6fc6b3a95ef4ff9040bcff3 66 Pfam PF00403 Heavy-metal-associated domain 5 62 5.2E-13 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS19760 0f9e42a4f6fc6b3a95ef4ff9040bcff3 66 SUPERFAMILY SSF55008 2 63 2.88E-14 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CVS48_RS07095 9cd10660f222daf3078f44619fb151fd 624 Gene3D G3DSA:3.40.50.720 283 618 3.0E-57 T 29-03-2018 CVS48_RS07095 9cd10660f222daf3078f44619fb151fd 624 SUPERFAMILY SSF51735 287 542 2.05E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07095 9cd10660f222daf3078f44619fb151fd 624 Gene3D G3DSA:3.40.50.720 147 270 1.3E-22 T 29-03-2018 CVS48_RS07095 9cd10660f222daf3078f44619fb151fd 624 Pfam PF02719 Polysaccharide biosynthesis protein 289 580 1.1E-122 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CVS48_RS07095 9cd10660f222daf3078f44619fb151fd 624 SUPERFAMILY SSF51735 152 273 2.76E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07095 9cd10660f222daf3078f44619fb151fd 624 Pfam PF13727 CoA-binding domain 83 245 4.6E-13 T 29-03-2018 CVS48_RS27140 6afefcce87ed82b46f833ede47563dba 132 SUPERFAMILY SSF55331 2 125 5.4E-22 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CVS48_RS27140 6afefcce87ed82b46f833ede47563dba 132 Gene3D G3DSA:3.30.429.10 1 66 2.1E-9 T 29-03-2018 CVS48_RS27140 6afefcce87ed82b46f833ede47563dba 132 Gene3D G3DSA:3.30.429.10 67 130 1.1E-11 T 29-03-2018 CVS48_RS26840 dc2fd99384e349ac0e7c4633600b0d68 254 Gene3D G3DSA:1.10.10.10 161 201 1.6E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26840 dc2fd99384e349ac0e7c4633600b0d68 254 Gene3D G3DSA:1.10.10.10 111 158 1.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26840 dc2fd99384e349ac0e7c4633600b0d68 254 Hamap MF_01114 Regulatory protein RecX [recX]. 110 254 13.667 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CVS48_RS26840 dc2fd99384e349ac0e7c4633600b0d68 254 Pfam PF02631 RecX family 140 252 5.7E-27 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CVS48_RS26840 dc2fd99384e349ac0e7c4633600b0d68 254 Gene3D G3DSA:1.10.10.10 206 254 1.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 SUPERFAMILY SSF47384 221 298 8.24E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 456 1.6E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 Gene3D G3DSA:1.10.287.130 219 297 5.3E-8 T 29-03-2018 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 Gene3D G3DSA:3.40.190.10 465 646 1.9E-15 T 29-03-2018 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 SUPERFAMILY SSF55874 292 459 2.75E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 Gene3D G3DSA:3.30.565.10 313 464 1.8E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 Pfam PF08521 Two-component sensor kinase N-terminal 25 162 5.1E-34 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 Pfam PF13531 Bacterial extracellular solute-binding protein 509 764 2.0E-18 T 29-03-2018 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 SUPERFAMILY SSF53850 506 780 5.12E-40 T 29-03-2018 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 SMART SM00387 348 458 6.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 Gene3D G3DSA:1.20.5.1040 129 186 1.1E-4 T 29-03-2018 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 Gene3D G3DSA:3.40.190.10 647 776 1.4E-8 T 29-03-2018 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 301 1.9E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS03220 e0ef8560f22c2cae530c28437a5d02e7 832 SMART SM00388 238 303 1.1E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS11970 671d3a0117c73b1a67c4c12addd93c55 263 Gene3D G3DSA:3.40.50.1820 8 263 4.4E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11970 671d3a0117c73b1a67c4c12addd93c55 263 Pfam PF00561 alpha/beta hydrolase fold 32 140 3.3E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11970 671d3a0117c73b1a67c4c12addd93c55 263 SUPERFAMILY SSF53474 13 260 4.92E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11970 671d3a0117c73b1a67c4c12addd93c55 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 1.4E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11970 671d3a0117c73b1a67c4c12addd93c55 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 1.4E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11970 671d3a0117c73b1a67c4c12addd93c55 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 1.4E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS26640 a9af3640cae4245e1fd640bd1ca2e6f1 411 Pfam PF12838 4Fe-4S dicluster domain 24 89 8.1E-13 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS26640 a9af3640cae4245e1fd640bd1ca2e6f1 411 Gene3D G3DSA:3.30.70.20 10 34 0.021 T 29-03-2018 CVS48_RS26640 a9af3640cae4245e1fd640bd1ca2e6f1 411 SUPERFAMILY SSF46548 20 101 2.04E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CVS48_RS26640 a9af3640cae4245e1fd640bd1ca2e6f1 411 Gene3D G3DSA:3.30.70.20 35 77 1.3E-8 T 29-03-2018 CVS48_RS26640 a9af3640cae4245e1fd640bd1ca2e6f1 411 Gene3D G3DSA:3.30.70.20 78 310 2.9E-4 T 29-03-2018 CVS48_RS26640 a9af3640cae4245e1fd640bd1ca2e6f1 411 PIRSF PIRSF000139 9 410 9.2E-111 T 29-03-2018 CVS48_RS26640 a9af3640cae4245e1fd640bd1ca2e6f1 411 Pfam PF02754 Cysteine-rich domain 304 386 3.3E-9 T 29-03-2018 IPR004017 Cysteine-rich domain CVS48_RS26640 a9af3640cae4245e1fd640bd1ca2e6f1 411 Pfam PF02754 Cysteine-rich domain 169 255 1.9E-8 T 29-03-2018 IPR004017 Cysteine-rich domain CVS48_RS26640 a9af3640cae4245e1fd640bd1ca2e6f1 411 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS09535 fd43b1a12170ea32fbd01c966d9152b6 286 Pfam PF13714 Phosphoenolpyruvate phosphomutase 16 252 2.3E-58 T 29-03-2018 CVS48_RS09535 fd43b1a12170ea32fbd01c966d9152b6 286 SUPERFAMILY SSF51621 9 283 1.53E-92 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS09535 fd43b1a12170ea32fbd01c966d9152b6 286 ProSitePatterns PS00161 Isocitrate lyase signature. 119 124 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CVS48_RS09535 fd43b1a12170ea32fbd01c966d9152b6 286 Gene3D G3DSA:3.20.20.60 3 286 7.2E-87 T 29-03-2018 CVS48_RS00255 75921c614375f65bcdb0998028b5505c 795 Pfam PF01580 FtsK/SpoIIIE family 406 615 9.7E-65 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CVS48_RS00255 75921c614375f65bcdb0998028b5505c 795 Pfam PF09397 Ftsk gamma domain 724 784 2.0E-26 T 29-03-2018 IPR018541 FtsK gamma domain CVS48_RS00255 75921c614375f65bcdb0998028b5505c 795 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 28 216 1.5E-45 T 29-03-2018 IPR025199 DNA translocase FtsK, 4TM region CVS48_RS00255 75921c614375f65bcdb0998028b5505c 795 SMART SM00382 441 636 0.0065 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS00255 75921c614375f65bcdb0998028b5505c 795 SMART SM00843 722 787 5.7E-38 T 29-03-2018 IPR018541 FtsK gamma domain CVS48_RS00255 75921c614375f65bcdb0998028b5505c 795 Gene3D G3DSA:1.10.10.10 724 778 2.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00255 75921c614375f65bcdb0998028b5505c 795 Gene3D G3DSA:3.40.50.300 227 656 3.6E-56 T 29-03-2018 CVS48_RS00255 75921c614375f65bcdb0998028b5505c 795 SUPERFAMILY SSF52540 423 686 6.11E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00255 75921c614375f65bcdb0998028b5505c 795 SUPERFAMILY SSF46785 722 786 2.88E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08285 3ee4306bf84225636c00ebb705426d83 377 Pfam PF13439 Glycosyltransferase Family 4 17 164 2.3E-13 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS08285 3ee4306bf84225636c00ebb705426d83 377 SUPERFAMILY SSF53756 6 358 1.31E-46 T 29-03-2018 CVS48_RS08285 3ee4306bf84225636c00ebb705426d83 377 Gene3D G3DSA:3.40.50.2000 172 345 3.6E-23 T 29-03-2018 CVS48_RS08285 3ee4306bf84225636c00ebb705426d83 377 Pfam PF13692 Glycosyl transferases group 1 184 314 2.1E-14 T 29-03-2018 CVS48_RS08285 3ee4306bf84225636c00ebb705426d83 377 Gene3D G3DSA:3.40.50.2000 3 171 1.6E-11 T 29-03-2018 CVS48_RS26850 3deb089ded56287c0fb91e99fbdf5243 229 SUPERFAMILY SSF52172 1 173 3.27E-36 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS26850 3deb089ded56287c0fb91e99fbdf5243 229 Pfam PF00072 Response regulator receiver domain 3 112 8.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS26850 3deb089ded56287c0fb91e99fbdf5243 229 Gene3D G3DSA:1.10.10.10 122 225 1.6E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26850 3deb089ded56287c0fb91e99fbdf5243 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 6.4E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS26850 3deb089ded56287c0fb91e99fbdf5243 229 Gene3D G3DSA:3.40.50.2300 1 121 1.4E-34 T 29-03-2018 CVS48_RS26850 3deb089ded56287c0fb91e99fbdf5243 229 SMART SM00862 145 218 7.5E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS26850 3deb089ded56287c0fb91e99fbdf5243 229 SMART SM00448 1 112 2.2E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS23875 70a18c727ee958d5d8dbee47abc8f92c 197 SUPERFAMILY SSF54626 32 196 8.11E-20 T 29-03-2018 IPR016087 Chalcone isomerase GO:0016872 CVS48_RS23875 70a18c727ee958d5d8dbee47abc8f92c 197 Gene3D G3DSA:3.50.70.10 16 180 1.6E-27 T 29-03-2018 IPR016088 Chalcone isomerase, 3-layer sandwich GO:0009813|GO:0045430 CVS48_RS23875 70a18c727ee958d5d8dbee47abc8f92c 197 Pfam PF16036 Chalcone isomerase-like 31 196 1.9E-48 T 29-03-2018 IPR016087 Chalcone isomerase GO:0016872 CVS48_RS03135 6eacabfaa206ba09c125e0450abe1c79 481 Gene3D G3DSA:3.40.50.980 113 134 5.5E-6 T 29-03-2018 CVS48_RS03135 6eacabfaa206ba09c125e0450abe1c79 481 Pfam PF13193 AMP-binding enzyme C-terminal domain 383 466 3.4E-5 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS03135 6eacabfaa206ba09c125e0450abe1c79 481 Gene3D G3DSA:3.40.50.980 135 285 1.9E-35 T 29-03-2018 CVS48_RS03135 6eacabfaa206ba09c125e0450abe1c79 481 Gene3D G3DSA:3.40.50.980 11 112 2.5E-16 T 29-03-2018 CVS48_RS03135 6eacabfaa206ba09c125e0450abe1c79 481 ProSitePatterns PS00455 Putative AMP-binding domain signature. 128 139 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS03135 6eacabfaa206ba09c125e0450abe1c79 481 SUPERFAMILY SSF56801 16 478 7.33E-112 T 29-03-2018 CVS48_RS03135 6eacabfaa206ba09c125e0450abe1c79 481 Gene3D G3DSA:3.30.300.30 369 480 4.1E-25 T 29-03-2018 CVS48_RS03135 6eacabfaa206ba09c125e0450abe1c79 481 Gene3D G3DSA:2.30.38.10 286 368 2.1E-13 T 29-03-2018 CVS48_RS03135 6eacabfaa206ba09c125e0450abe1c79 481 Pfam PF00501 AMP-binding enzyme 16 374 2.3E-66 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS07440 745d566ca5178fd0dd711065b92240b6 324 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 319 3.7E-102 T 29-03-2018 IPR007296 Domain of unknown function DUF403 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 Gene3D G3DSA:1.10.760.10 589 732 5.2E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 SUPERFAMILY SSF56003 332 439 1.19E-11 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 SUPERFAMILY SSF56003 528 565 1.38E-6 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 SUPERFAMILY SSF46626 616 741 9.99E-24 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 Pfam PF00034 Cytochrome c 619 718 2.0E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 SUPERFAMILY SSF46626 916 1032 9.03E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 936 1017 1.3E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 Gene3D G3DSA:3.30.365.10 332 457 4.4E-11 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 SUPERFAMILY SSF46626 747 871 1.31E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 Gene3D G3DSA:1.10.760.10 907 1044 1.2E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 Gene3D G3DSA:1.10.760.10 744 906 2.5E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS09670 0209b79998c619a3ff1d13284db5fe20 1045 Gene3D G3DSA:3.30.365.10 518 569 9.1E-8 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CVS48_RS11415 9ea73f58bdc0d6bbefefd6fb45feb008 318 Gene3D G3DSA:3.40.50.2000 150 314 4.6E-21 T 29-03-2018 CVS48_RS11415 9ea73f58bdc0d6bbefefd6fb45feb008 318 Gene3D G3DSA:3.40.50.2000 5 144 4.6E-9 T 29-03-2018 CVS48_RS11415 9ea73f58bdc0d6bbefefd6fb45feb008 318 SUPERFAMILY SSF53756 8 309 2.13E-38 T 29-03-2018 CVS48_RS11415 9ea73f58bdc0d6bbefefd6fb45feb008 318 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 116 272 2.5E-9 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CVS48_RS23045 f3c0406a4654b0061da244c3f4ecc6fd 509 SUPERFAMILY SSF56176 21 202 9.35E-28 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS23045 f3c0406a4654b0061da244c3f4ecc6fd 509 Gene3D G3DSA:3.30.43.10 2 80 8.3E-8 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS23045 f3c0406a4654b0061da244c3f4ecc6fd 509 Pfam PF01565 FAD binding domain 35 161 5.2E-11 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS23045 f3c0406a4654b0061da244c3f4ecc6fd 509 Pfam PF08031 Berberine and berberine like 459 508 8.5E-15 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CVS48_RS23045 f3c0406a4654b0061da244c3f4ecc6fd 509 Gene3D G3DSA:3.30.465.10 90 226 3.8E-21 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS16045 b7396e219078cfccb151d36425043a5d 144 SUPERFAMILY SSF46955 1 113 1.36E-32 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS16045 b7396e219078cfccb151d36425043a5d 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.6E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS16045 b7396e219078cfccb151d36425043a5d 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.6E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS16045 b7396e219078cfccb151d36425043a5d 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.6E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS16045 b7396e219078cfccb151d36425043a5d 144 SMART SM00422 1 70 6.3E-25 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS16045 b7396e219078cfccb151d36425043a5d 144 Gene3D G3DSA:1.10.1660.10 1 56 1.1E-21 T 29-03-2018 CVS48_RS16045 b7396e219078cfccb151d36425043a5d 144 Pfam PF13411 MerR HTH family regulatory protein 1 68 5.9E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS16045 b7396e219078cfccb151d36425043a5d 144 Gene3D G3DSA:1.10.1660.10 57 139 1.0E-18 T 29-03-2018 CVS48_RS16045 b7396e219078cfccb151d36425043a5d 144 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 128 1.5E-48 T 29-03-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 CVS48_RS11810 64f65ec7d2bfccc09fbf31e65846af25 326 PIRSF PIRSF017082 1 326 2.9E-79 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11810 64f65ec7d2bfccc09fbf31e65846af25 326 SUPERFAMILY SSF53850 113 281 1.71E-13 T 29-03-2018 CVS48_RS11810 64f65ec7d2bfccc09fbf31e65846af25 326 Gene3D G3DSA:3.40.190.10 123 323 2.6E-13 T 29-03-2018 CVS48_RS11810 64f65ec7d2bfccc09fbf31e65846af25 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 322 5.6E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11220 fb6d64a997a0163147f8096c05e80c24 509 Gene3D G3DSA:2.30.38.10 318 401 1.8E-15 T 29-03-2018 CVS48_RS11220 fb6d64a997a0163147f8096c05e80c24 509 Gene3D G3DSA:3.30.300.30 403 509 1.4E-24 T 29-03-2018 CVS48_RS11220 fb6d64a997a0163147f8096c05e80c24 509 Gene3D G3DSA:3.40.50.980 1 165 1.6E-30 T 29-03-2018 CVS48_RS11220 fb6d64a997a0163147f8096c05e80c24 509 Pfam PF00501 AMP-binding enzyme 5 408 4.7E-73 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS11220 fb6d64a997a0163147f8096c05e80c24 509 Gene3D G3DSA:3.40.50.980 166 317 1.2E-33 T 29-03-2018 CVS48_RS11220 fb6d64a997a0163147f8096c05e80c24 509 SUPERFAMILY SSF56801 3 507 1.44E-121 T 29-03-2018 CVS48_RS11220 fb6d64a997a0163147f8096c05e80c24 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 495 3.8E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS23965 a7f39f0bb2775579832dec04eaa87d85 239 SUPERFAMILY SSF52096 2 238 1.4E-41 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS23965 a7f39f0bb2775579832dec04eaa87d85 239 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 206 5.3E-25 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS23965 a7f39f0bb2775579832dec04eaa87d85 239 Gene3D G3DSA:3.90.226.10 1 226 3.0E-39 T 29-03-2018 CVS48_RS10065 d2984242e1811607edf11574b773b0b2 516 Pfam PF01266 FAD dependent oxidoreductase 110 464 1.7E-48 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS10065 d2984242e1811607edf11574b773b0b2 516 Gene3D G3DSA:3.50.50.60 96 487 2.2E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10065 d2984242e1811607edf11574b773b0b2 516 SUPERFAMILY SSF51905 438 487 6.91E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS10065 d2984242e1811607edf11574b773b0b2 516 SUPERFAMILY SSF51905 108 366 6.91E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS27225 f3111cb3c89d15ecd9fb186b8002e91a 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 81 3.2E-16 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS27225 f3111cb3c89d15ecd9fb186b8002e91a 214 SUPERFAMILY SSF52833 1 85 2.41E-23 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS27225 f3111cb3c89d15ecd9fb186b8002e91a 214 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 213 2.4E-92 T 29-03-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 CVS48_RS27225 f3111cb3c89d15ecd9fb186b8002e91a 214 Gene3D G3DSA:1.20.1050.10 91 214 6.0E-26 T 29-03-2018 CVS48_RS27225 f3111cb3c89d15ecd9fb186b8002e91a 214 Gene3D G3DSA:3.40.30.10 1 90 2.7E-27 T 29-03-2018 CVS48_RS27225 f3111cb3c89d15ecd9fb186b8002e91a 214 SUPERFAMILY SSF47616 82 212 3.06E-33 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS27225 f3111cb3c89d15ecd9fb186b8002e91a 214 Pfam PF14497 Glutathione S-transferase, C-terminal domain 126 202 2.6E-6 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS28420 98764f00e76ed8788061e599871daaa9 277 Pfam PF06167 Glucose-regulated metallo-peptidase M90 18 269 1.7E-76 T 29-03-2018 IPR010384 MtfA family CVS48_RS28420 98764f00e76ed8788061e599871daaa9 277 SUPERFAMILY SSF55486 43 196 1.76E-35 T 29-03-2018 CVS48_RS28420 98764f00e76ed8788061e599871daaa9 277 SUPERFAMILY SSF55486 228 271 1.76E-35 T 29-03-2018 CVS48_RS28420 98764f00e76ed8788061e599871daaa9 277 Gene3D G3DSA:3.40.390.10 83 272 2.2E-23 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 Pfam PF02743 Cache domain 35 263 1.7E-25 T 29-03-2018 IPR033479 Double Cache domain 1 CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 SMART SM00267 350 515 8.4E-51 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 SUPERFAMILY SSF103190 183 252 8.24E-10 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 SUPERFAMILY SSF55073 366 516 1.18E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 Gene3D G3DSA:3.30.450.20 161 278 5.0E-18 T 29-03-2018 CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 Gene3D G3DSA:3.30.450.20 80 160 5.7E-11 T 29-03-2018 CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 357 515 1.6E-40 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 SUPERFAMILY SSF103190 60 178 1.26E-8 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 Gene3D G3DSA:3.30.70.270 355 518 1.9E-51 T 29-03-2018 CVS48_RS18865 0b3df308f5c7f23dacd100ee07db30f7 518 Pfam PF00990 Diguanylate cyclase, GGDEF domain 362 511 3.8E-39 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS21350 1b8516787105b65570e71393b242391d 394 Pfam PF01266 FAD dependent oxidoreductase 7 367 8.2E-45 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS21350 1b8516787105b65570e71393b242391d 394 SUPERFAMILY SSF51905 5 236 2.07E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21350 1b8516787105b65570e71393b242391d 394 SUPERFAMILY SSF51905 329 377 2.07E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21350 1b8516787105b65570e71393b242391d 394 Gene3D G3DSA:3.50.50.60 1 206 2.6E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21350 1b8516787105b65570e71393b242391d 394 Gene3D G3DSA:3.30.9.10 207 328 3.0E-21 T 29-03-2018 CVS48_RS09370 8ff11c8dd60aa6ebcbec5c53f63f59af 366 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 174 360 8.8E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09370 8ff11c8dd60aa6ebcbec5c53f63f59af 366 SUPERFAMILY SSF161098 155 346 6.67E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09370 8ff11c8dd60aa6ebcbec5c53f63f59af 366 Gene3D G3DSA:1.10.3720.10 26 366 9.4E-40 T 29-03-2018 CVS48_RS09370 8ff11c8dd60aa6ebcbec5c53f63f59af 366 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 156 252 2.6E-19 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS07135 2f110f2e7335477110de395efc1a2c12 189 Gene3D G3DSA:2.160.10.10 2 39 1.1E-11 T 29-03-2018 CVS48_RS07135 2f110f2e7335477110de395efc1a2c12 189 Gene3D G3DSA:2.160.10.10 40 164 3.1E-34 T 29-03-2018 CVS48_RS07135 2f110f2e7335477110de395efc1a2c12 189 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 100 134 3.7E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS07135 2f110f2e7335477110de395efc1a2c12 189 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 30 63 3.2E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS07135 2f110f2e7335477110de395efc1a2c12 189 SUPERFAMILY SSF51161 2 157 1.8E-43 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS27315 ce3dcec6a5d0b7fbd8b0e0826b92b96e 309 Pfam PF07848 PaaX-like protein 22 91 2.2E-27 T 29-03-2018 IPR012906 PaaX-like, N-terminal CVS48_RS27315 ce3dcec6a5d0b7fbd8b0e0826b92b96e 309 Gene3D G3DSA:1.10.10.10 21 104 3.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27315 ce3dcec6a5d0b7fbd8b0e0826b92b96e 309 PIRSF PIRSF020623 1 308 4.1E-111 T 29-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CVS48_RS27315 ce3dcec6a5d0b7fbd8b0e0826b92b96e 309 Pfam PF08223 PaaX-like protein C-terminal domain 190 283 4.3E-30 T 29-03-2018 IPR013225 PaaX-like, C-terminal CVS48_RS27315 ce3dcec6a5d0b7fbd8b0e0826b92b96e 309 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 25 305 5.1E-112 T 29-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CVS48_RS16860 4d6ac0af1c370cc6dc38d18153a5ad02 135 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 134 3.4E-40 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CVS48_RS16860 4d6ac0af1c370cc6dc38d18153a5ad02 135 Pfam PF00460 Flagella basal body rod protein 13 39 2.8E-9 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CVS48_RS16860 4d6ac0af1c370cc6dc38d18153a5ad02 135 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CVS48_RS16860 4d6ac0af1c370cc6dc38d18153a5ad02 135 PIRSF PIRSF002889 1 135 1.1E-44 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CVS48_RS18440 030e4a9c5fa9a9b748e835cee1a0df5f 240 Gene3D G3DSA:3.50.30.40 14 205 1.8E-47 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS18440 030e4a9c5fa9a9b748e835cee1a0df5f 240 SUPERFAMILY SSF89562 18 196 2.49E-36 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS18440 030e4a9c5fa9a9b748e835cee1a0df5f 240 Pfam PF03737 Aldolase/RraA 32 184 1.0E-27 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS21905 9667a7cad98e7c448b99756bc603b130 113 Gene3D G3DSA:3.10.20.30 14 113 2.0E-27 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS21905 9667a7cad98e7c448b99756bc603b130 113 PRINTS PR00355 Adrenodoxin signature 84 92 2.9E-9 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CVS48_RS21905 9667a7cad98e7c448b99756bc603b130 113 PRINTS PR00355 Adrenodoxin signature 43 53 2.9E-9 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CVS48_RS21905 9667a7cad98e7c448b99756bc603b130 113 PRINTS PR00355 Adrenodoxin signature 61 75 2.9E-9 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CVS48_RS21905 9667a7cad98e7c448b99756bc603b130 113 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 5.0E-52 T 29-03-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 CVS48_RS21905 9667a7cad98e7c448b99756bc603b130 113 SUPERFAMILY SSF54292 8 109 5.0E-27 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS21905 9667a7cad98e7c448b99756bc603b130 113 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 19 93 7.8E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS21905 9667a7cad98e7c448b99756bc603b130 113 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 43 53 - T 29-03-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CVS48_RS19945 338dd432fd600a5beefbbb577ee678bd 293 SUPERFAMILY SSF103481 191 284 1.27E-11 T 29-03-2018 CVS48_RS19945 338dd432fd600a5beefbbb577ee678bd 293 SUPERFAMILY SSF103481 44 141 9.02E-9 T 29-03-2018 CVS48_RS19945 338dd432fd600a5beefbbb577ee678bd 293 Pfam PF00892 EamA-like transporter family 16 138 1.1E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS19945 338dd432fd600a5beefbbb577ee678bd 293 Pfam PF00892 EamA-like transporter family 151 281 5.8E-10 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 SUPERFAMILY SSF53720 19 420 2.55E-66 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 3 420 32.277 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 PIRSF PIRSF000099 3 423 2.5E-120 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 Gene3D G3DSA:3.40.50.1980 18 217 1.6E-73 T 29-03-2018 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 Pfam PF00815 Histidinol dehydrogenase 15 420 3.9E-136 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 221 253 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 25 419 8.5E-135 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 PRINTS PR00083 Histidinol dehydrogenase signature 162 188 1.1E-66 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 PRINTS PR00083 Histidinol dehydrogenase signature 192 217 1.1E-66 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 PRINTS PR00083 Histidinol dehydrogenase signature 221 242 1.1E-66 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 PRINTS PR00083 Histidinol dehydrogenase signature 353 371 1.1E-66 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 PRINTS PR00083 Histidinol dehydrogenase signature 100 127 1.1E-66 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 PRINTS PR00083 Histidinol dehydrogenase signature 243 262 1.1E-66 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 PRINTS PR00083 Histidinol dehydrogenase signature 25 49 1.1E-66 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 PRINTS PR00083 Histidinol dehydrogenase signature 312 337 1.1E-66 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CVS48_RS08695 56d2e4eef9fdb601605489762b277237 439 Gene3D G3DSA:3.40.50.1980 218 363 1.6E-57 T 29-03-2018 CVS48_RS10605 a48dc72102e67c3ee109597d6089916c 469 Gene3D G3DSA:3.90.1300.10 1 469 4.8E-117 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS10605 a48dc72102e67c3ee109597d6089916c 469 SUPERFAMILY SSF75304 3 455 6.02E-117 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS10605 a48dc72102e67c3ee109597d6089916c 469 Pfam PF01425 Amidase 25 446 4.7E-82 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS16135 91500c15f93fe3dc4d3fab67ef37b56f 401 Pfam PF00482 Type II secretion system (T2SS), protein F 68 190 5.3E-32 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS16135 91500c15f93fe3dc4d3fab67ef37b56f 401 Pfam PF00482 Type II secretion system (T2SS), protein F 270 392 8.8E-27 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS16135 91500c15f93fe3dc4d3fab67ef37b56f 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 162 190 4.8E-28 T 29-03-2018 IPR003004 GspF/PilC family CVS48_RS16135 91500c15f93fe3dc4d3fab67ef37b56f 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 365 379 4.8E-28 T 29-03-2018 IPR003004 GspF/PilC family CVS48_RS16135 91500c15f93fe3dc4d3fab67ef37b56f 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 63 75 4.8E-28 T 29-03-2018 IPR003004 GspF/PilC family CVS48_RS16135 91500c15f93fe3dc4d3fab67ef37b56f 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 381 400 4.8E-28 T 29-03-2018 IPR003004 GspF/PilC family CVS48_RS16135 91500c15f93fe3dc4d3fab67ef37b56f 401 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 400 6.9E-156 T 29-03-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 Gene3D G3DSA:3.40.190.10 89 172 2.1E-16 T 29-03-2018 CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 Pfam PF03466 LysR substrate binding domain 91 291 9.9E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 Gene3D G3DSA:1.10.10.10 2 85 2.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 SUPERFAMILY SSF53850 92 294 4.83E-41 T 29-03-2018 CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 Gene3D G3DSA:3.40.190.10 173 260 1.7E-19 T 29-03-2018 CVS48_RS16350 99da36e77c320ee26cf11d09bf8d9bf8 298 SUPERFAMILY SSF46785 3 111 6.64E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03975 e0023b4c143d11fc3563e26f8ed0753d 323 Gene3D G3DSA:3.20.20.70 11 323 6.4E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS03975 e0023b4c143d11fc3563e26f8ed0753d 323 SUPERFAMILY SSF51412 13 296 2.93E-59 T 29-03-2018 CVS48_RS03975 e0023b4c143d11fc3563e26f8ed0753d 323 Pfam PF03060 Nitronate monooxygenase 87 255 3.7E-22 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CVS48_RS27975 2d92f144d2c229d46bfbc584a75ac781 309 Gene3D G3DSA:3.90.1280.10 239 294 6.1E-22 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CVS48_RS27975 2d92f144d2c229d46bfbc584a75ac781 309 PIRSF PIRSF005261 1 298 3.4E-72 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CVS48_RS27975 2d92f144d2c229d46bfbc584a75ac781 309 Pfam PF01430 Hsp33 protein 3 286 2.5E-81 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CVS48_RS27975 2d92f144d2c229d46bfbc584a75ac781 309 Gene3D G3DSA:1.10.287.480 194 238 5.8E-15 T 29-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain CVS48_RS27975 2d92f144d2c229d46bfbc584a75ac781 309 SUPERFAMILY SSF118352 238 295 1.83E-18 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CVS48_RS27975 2d92f144d2c229d46bfbc584a75ac781 309 SUPERFAMILY SSF64397 3 245 1.44E-60 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CVS48_RS27975 2d92f144d2c229d46bfbc584a75ac781 309 Gene3D G3DSA:3.55.30.10 1 179 5.9E-57 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CVS48_RS27975 2d92f144d2c229d46bfbc584a75ac781 309 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 297 28.26 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CVS48_RS20505 7e45b1d33455915969ef44277971ff8a 418 Gene3D G3DSA:3.30.565.40 203 309 8.2E-9 T 29-03-2018 CVS48_RS12215 c8ededdbf6995d55728554ab1387715f 169 SUPERFAMILY SSF88659 105 166 2.99E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12215 c8ededdbf6995d55728554ab1387715f 169 Pfam PF04542 Sigma-70 region 2 16 79 2.6E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12215 c8ededdbf6995d55728554ab1387715f 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 161 7.0E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12215 c8ededdbf6995d55728554ab1387715f 169 Pfam PF08281 Sigma-70, region 4 111 163 8.8E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12215 c8ededdbf6995d55728554ab1387715f 169 Gene3D G3DSA:1.10.1740.10 8 83 3.7E-14 T 29-03-2018 CVS48_RS12215 c8ededdbf6995d55728554ab1387715f 169 SUPERFAMILY SSF88946 13 97 3.45E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS12215 c8ededdbf6995d55728554ab1387715f 169 Gene3D G3DSA:1.10.10.10 105 167 1.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15470 ad306371e97952cc2d5421855d09a147 84 SUPERFAMILY SSF47336 3 82 2.09E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS15470 ad306371e97952cc2d5421855d09a147 84 Gene3D G3DSA:1.10.1200.10 1 81 7.5E-18 T 29-03-2018 CVS48_RS15470 ad306371e97952cc2d5421855d09a147 84 Pfam PF00550 Phosphopantetheine attachment site 10 75 2.4E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS14660 8ac992dd0fdf1127b1232e5184e46c00 243 Pfam PF00005 ABC transporter 17 165 3.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS14660 8ac992dd0fdf1127b1232e5184e46c00 243 PIRSF PIRSF039085 1 241 4.6E-114 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS14660 8ac992dd0fdf1127b1232e5184e46c00 243 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS14660 8ac992dd0fdf1127b1232e5184e46c00 243 Gene3D G3DSA:3.40.50.300 1 242 1.0E-74 T 29-03-2018 CVS48_RS14660 8ac992dd0fdf1127b1232e5184e46c00 243 SMART SM00382 26 213 6.3E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS14660 8ac992dd0fdf1127b1232e5184e46c00 243 SUPERFAMILY SSF52540 1 235 7.62E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS24410 70289fcbd24e8a31376e51a731fbf515 116 Gene3D G3DSA:2.40.300.10 2 113 1.1E-21 T 29-03-2018 CVS48_RS24410 70289fcbd24e8a31376e51a731fbf515 116 Pfam PF02924 Bacteriophage lambda head decoration protein D 3 104 4.9E-28 T 29-03-2018 IPR004195 Head decoration protein D GO:0019028 CVS48_RS05560 d0501106d9558457487dd833374501a2 462 SMART SM00387 356 457 6.4E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS05560 d0501106d9558457487dd833374501a2 462 Gene3D G3DSA:3.30.565.10 320 460 9.9E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS05560 d0501106d9558457487dd833374501a2 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 2.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS05560 d0501106d9558457487dd833374501a2 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 2.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS05560 d0501106d9558457487dd833374501a2 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 2.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS05560 d0501106d9558457487dd833374501a2 462 SMART SM00388 250 316 1.9E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS05560 d0501106d9558457487dd833374501a2 462 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 309 3.1E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS05560 d0501106d9558457487dd833374501a2 462 SUPERFAMILY SSF55874 323 457 8.12E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS05560 d0501106d9558457487dd833374501a2 462 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 456 3.9E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS05560 d0501106d9558457487dd833374501a2 462 SUPERFAMILY SSF47384 236 313 4.32E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS05560 d0501106d9558457487dd833374501a2 462 Gene3D G3DSA:1.10.287.130 233 312 1.0E-8 T 29-03-2018 CVS48_RS26245 daf2e153880f733e5fbe28f751c529a4 306 SUPERFAMILY SSF161098 15 292 6.64E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS26245 daf2e153880f733e5fbe28f751c529a4 306 Gene3D G3DSA:1.10.3720.10 14 299 5.5E-43 T 29-03-2018 CVS48_RS26245 daf2e153880f733e5fbe28f751c529a4 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 290 8.6E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28570 ea61b9ad47c2d62028be886c9927e87a 437 Gene3D G3DSA:1.20.1250.20 1 218 5.6E-17 T 29-03-2018 CVS48_RS28570 ea61b9ad47c2d62028be886c9927e87a 437 Pfam PF07690 Major Facilitator Superfamily 11 349 1.2E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS28570 ea61b9ad47c2d62028be886c9927e87a 437 SUPERFAMILY SSF103473 3 414 5.1E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS28570 ea61b9ad47c2d62028be886c9927e87a 437 Gene3D G3DSA:1.20.1250.20 228 423 1.7E-8 T 29-03-2018 CVS48_RS00460 6af0e20f18a41bf2377cec5d914d18f6 178 Pfam PF04355 SmpA / OmlA family 42 111 3.9E-24 T 29-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 CVS48_RS00460 6af0e20f18a41bf2377cec5d914d18f6 178 Gene3D G3DSA:3.30.1450.10 42 117 1.5E-16 T 29-03-2018 CVS48_RS00460 6af0e20f18a41bf2377cec5d914d18f6 178 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 12 120 26.978 T 29-03-2018 IPR026592 Outer membrane protein assembly factor BamE CVS48_RS12985 ce044f1a1bd6054e5071ada8d30cb1b8 244 Pfam PF01411 tRNA synthetases class II (A) 21 103 2.2E-7 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CVS48_RS12985 ce044f1a1bd6054e5071ada8d30cb1b8 244 SMART SM00863 197 240 1.6E-14 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CVS48_RS12985 ce044f1a1bd6054e5071ada8d30cb1b8 244 SUPERFAMILY SSF50447 7 99 3.88E-12 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS12985 ce044f1a1bd6054e5071ada8d30cb1b8 244 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 197 240 1.8E-12 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CVS48_RS12985 ce044f1a1bd6054e5071ada8d30cb1b8 244 SUPERFAMILY SSF55186 104 240 1.01E-30 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CVS48_RS12985 ce044f1a1bd6054e5071ada8d30cb1b8 244 Gene3D G3DSA:3.30.980.10 101 243 5.7E-27 T 29-03-2018 CVS48_RS11430 b989eb8f8719246caafb9685f8b0f5df 105 Gene3D G3DSA:3.30.70.100 1 104 2.0E-23 T 29-03-2018 CVS48_RS11430 b989eb8f8719246caafb9685f8b0f5df 105 SUPERFAMILY SSF54909 1 104 4.29E-26 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS11430 b989eb8f8719246caafb9685f8b0f5df 105 Pfam PF07978 NIPSNAP 3 102 3.2E-24 T 29-03-2018 IPR012577 NIPSNAP CVS48_RS22900 1ce49ef9b94c84091ff8162afbac8ad8 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 316 1.3E-64 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22900 1ce49ef9b94c84091ff8162afbac8ad8 319 SUPERFAMILY SSF53850 106 282 7.61E-15 T 29-03-2018 CVS48_RS22900 1ce49ef9b94c84091ff8162afbac8ad8 319 PIRSF PIRSF017082 1 319 1.6E-70 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22900 1ce49ef9b94c84091ff8162afbac8ad8 319 Gene3D G3DSA:3.40.190.10 128 288 2.6E-11 T 29-03-2018 CVS48_RS03495 a0b97d05e1ada0c7ab50cc8a2adffb7f 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 12 408 5.3E-118 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS03495 a0b97d05e1ada0c7ab50cc8a2adffb7f 408 SUPERFAMILY SSF56266 16 405 6.15E-134 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS03495 a0b97d05e1ada0c7ab50cc8a2adffb7f 408 Gene3D G3DSA:3.60.70.12 8 279 2.9E-102 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS03495 a0b97d05e1ada0c7ab50cc8a2adffb7f 408 Pfam PF01960 ArgJ family 22 408 7.9E-138 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS03495 a0b97d05e1ada0c7ab50cc8a2adffb7f 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 154.451 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS03495 a0b97d05e1ada0c7ab50cc8a2adffb7f 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 25 406 8.0E-177 T 29-03-2018 CVS48_RS11610 0c5860f274166f1dbd219c92bc346870 322 PIRSF PIRSF017082 1 321 6.8E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11610 0c5860f274166f1dbd219c92bc346870 322 SUPERFAMILY SSF53850 109 285 3.17E-18 T 29-03-2018 CVS48_RS11610 0c5860f274166f1dbd219c92bc346870 322 Gene3D G3DSA:3.40.190.10 122 232 5.9E-16 T 29-03-2018 CVS48_RS11610 0c5860f274166f1dbd219c92bc346870 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 1.2E-93 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 Gene3D G3DSA:3.40.190.10 182 271 2.9E-25 T 29-03-2018 CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 Gene3D G3DSA:1.10.10.10 1 88 1.8E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 Pfam PF03466 LysR substrate binding domain 92 296 1.2E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 SUPERFAMILY SSF53850 95 298 5.12E-45 T 29-03-2018 CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 SUPERFAMILY SSF46785 5 116 2.91E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 Gene3D G3DSA:3.40.190.10 92 181 2.5E-22 T 29-03-2018 CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12700 88f32d991ef9f08d3cb04a93acd084a4 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.8E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10595 9652522aebe69a8a45c52dcc04a44362 652 Pfam PF10722 Putative bacterial sensory transduction regulator 521 647 6.1E-14 T 29-03-2018 IPR019660 Putative sensory transduction regulator YbjN CVS48_RS10595 9652522aebe69a8a45c52dcc04a44362 652 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 472 1.3E-105 T 29-03-2018 IPR010352 Protein of unknown function DUF945 CVS48_RS20080 e48fc91e3ce062b6ab620b7618fe956b 491 Pfam PF02321 Outer membrane efflux protein 290 465 5.4E-30 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS20080 e48fc91e3ce062b6ab620b7618fe956b 491 Pfam PF02321 Outer membrane efflux protein 64 257 1.9E-16 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS20080 e48fc91e3ce062b6ab620b7618fe956b 491 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 8 467 3.2E-110 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS20080 e48fc91e3ce062b6ab620b7618fe956b 491 SUPERFAMILY SSF56954 2 23 4.84E-98 T 29-03-2018 CVS48_RS20080 e48fc91e3ce062b6ab620b7618fe956b 491 SUPERFAMILY SSF56954 55 470 4.84E-98 T 29-03-2018 CVS48_RS20080 e48fc91e3ce062b6ab620b7618fe956b 491 Gene3D G3DSA:1.20.1600.10 13 473 2.8E-92 T 29-03-2018 CVS48_RS03740 503dc273afa07066994e8f6b12a9b220 334 SUPERFAMILY SSF54427 209 329 7.85E-15 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS03740 503dc273afa07066994e8f6b12a9b220 334 SMART SM00978 200 327 1.2E-34 T 29-03-2018 IPR007379 Tim44-like domain CVS48_RS03740 503dc273afa07066994e8f6b12a9b220 334 Pfam PF04280 Tim44-like domain 209 327 1.5E-11 T 29-03-2018 IPR007379 Tim44-like domain CVS48_RS04670 ad82e88f1f08f9286b2608b1aaac7ff8 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 318 6.2E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04670 ad82e88f1f08f9286b2608b1aaac7ff8 322 SUPERFAMILY SSF53850 109 286 5.93E-13 T 29-03-2018 CVS48_RS04670 ad82e88f1f08f9286b2608b1aaac7ff8 322 Gene3D G3DSA:3.40.190.10 122 236 1.8E-13 T 29-03-2018 CVS48_RS04670 ad82e88f1f08f9286b2608b1aaac7ff8 322 PIRSF PIRSF017082 1 321 8.9E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS02690 a746e40520ab3f639f31a30d4aa37bb2 390 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 316 377 1.8E-10 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CVS48_RS02690 a746e40520ab3f639f31a30d4aa37bb2 390 TIGRFAM TIGR02794 tolA_full: protein TolA 22 381 7.0E-54 T 29-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 CVS48_RS02690 a746e40520ab3f639f31a30d4aa37bb2 390 Gene3D G3DSA:3.30.1150.10 288 388 8.9E-16 T 29-03-2018 CVS48_RS02690 a746e40520ab3f639f31a30d4aa37bb2 390 SUPERFAMILY SSF101447 97 106 1.39E-5 T 29-03-2018 CVS48_RS02690 a746e40520ab3f639f31a30d4aa37bb2 390 Pfam PF13103 TonB C terminal 301 379 1.1E-13 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CVS48_RS02690 a746e40520ab3f639f31a30d4aa37bb2 390 SUPERFAMILY SSF74653 298 379 1.7E-12 T 29-03-2018 CVS48_RS09365 571cea621395cc9f3356110f37259b25 396 SUPERFAMILY SSF161098 89 156 4.09E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09365 571cea621395cc9f3356110f37259b25 396 Gene3D G3DSA:1.10.3720.10 26 396 3.7E-48 T 29-03-2018 CVS48_RS09365 571cea621395cc9f3356110f37259b25 396 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 88 152 5.9E-17 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS09365 571cea621395cc9f3356110f37259b25 396 SUPERFAMILY SSF161098 189 377 9.81E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09365 571cea621395cc9f3356110f37259b25 396 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 266 391 8.2E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18325 221df828b4aeaf9a0d282d363fc47434 525 PIRSF PIRSF002741 6 525 4.5E-140 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS18325 221df828b4aeaf9a0d282d363fc47434 525 Gene3D G3DSA:3.40.190.10 149 289 2.0E-45 T 29-03-2018 CVS48_RS18325 221df828b4aeaf9a0d282d363fc47434 525 Gene3D G3DSA:3.10.105.10 290 496 1.1E-47 T 29-03-2018 CVS48_RS18325 221df828b4aeaf9a0d282d363fc47434 525 SUPERFAMILY SSF53850 26 523 1.59E-132 T 29-03-2018 CVS48_RS18325 221df828b4aeaf9a0d282d363fc47434 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 430 5.4E-89 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS18325 221df828b4aeaf9a0d282d363fc47434 525 Gene3D G3DSA:3.90.76.10 52 148 8.1E-32 T 29-03-2018 CVS48_RS24070 7df55f443c2935abdd4eb68aa2705c5c 255 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 255 95.048 T 29-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 CVS48_RS24070 7df55f443c2935abdd4eb68aa2705c5c 255 Pfam PF00149 Calcineurin-like phosphoesterase 9 208 1.6E-7 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS24070 7df55f443c2935abdd4eb68aa2705c5c 255 Gene3D G3DSA:3.60.21.10 10 237 1.2E-20 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS24070 7df55f443c2935abdd4eb68aa2705c5c 255 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 13 229 2.2E-65 T 29-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 CVS48_RS24070 7df55f443c2935abdd4eb68aa2705c5c 255 SUPERFAMILY SSF56300 10 229 6.21E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS07255 1766a108c0d33ff4509bd3a7f7f8c61f 373 SUPERFAMILY SSF90002 277 371 3.01E-25 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS07255 1766a108c0d33ff4509bd3a7f7f8c61f 373 Gene3D G3DSA:3.40.50.300 8 212 1.8E-45 T 29-03-2018 CVS48_RS07255 1766a108c0d33ff4509bd3a7f7f8c61f 373 SMART SM00833 277 371 2.1E-17 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS07255 1766a108c0d33ff4509bd3a7f7f8c61f 373 Gene3D G3DSA:3.30.1220.10 231 372 2.0E-26 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS07255 1766a108c0d33ff4509bd3a7f7f8c61f 373 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 277 371 1.7E-21 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS07255 1766a108c0d33ff4509bd3a7f7f8c61f 373 SUPERFAMILY SSF52540 12 217 3.81E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07255 1766a108c0d33ff4509bd3a7f7f8c61f 373 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 193 1.8E-50 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CVS48_RS25675 b2a12e13f338b1ace7bbdbb75b423dff 328 SUPERFAMILY SSF53448 5 231 2.53E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS25675 b2a12e13f338b1ace7bbdbb75b423dff 328 Pfam PF00535 Glycosyl transferase family 2 10 128 5.5E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS25675 b2a12e13f338b1ace7bbdbb75b423dff 328 Gene3D G3DSA:3.90.550.10 2 245 1.9E-41 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS25435 07755b067fd96cfec73d7fca79f5500b 369 SUPERFAMILY SSF54534 196 302 1.44E-24 T 29-03-2018 CVS48_RS25435 07755b067fd96cfec73d7fca79f5500b 369 Gene3D G3DSA:3.10.50.40 189 325 5.6E-30 T 29-03-2018 CVS48_RS25435 07755b067fd96cfec73d7fca79f5500b 369 Pfam PF00639 PPIC-type PPIASE domain 215 298 3.5E-20 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CVS48_RS25435 07755b067fd96cfec73d7fca79f5500b 369 SUPERFAMILY SSF109998 88 224 3.92E-7 T 29-03-2018 IPR027304 Trigger factor/SurA domain CVS48_RS25435 07755b067fd96cfec73d7fca79f5500b 369 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 238 259 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CVS48_RS09355 917acb43169c89c8bc0aab5d3528d71c 252 Gene3D G3DSA:3.40.50.300 1 224 3.4E-60 T 29-03-2018 CVS48_RS09355 917acb43169c89c8bc0aab5d3528d71c 252 SUPERFAMILY SSF52540 1 220 2.44E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09355 917acb43169c89c8bc0aab5d3528d71c 252 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS09355 917acb43169c89c8bc0aab5d3528d71c 252 SMART SM00382 27 214 2.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS09355 917acb43169c89c8bc0aab5d3528d71c 252 Pfam PF00005 ABC transporter 18 166 1.0E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS24715 d51e0d8471587d5c0df2f448a113aff7 245 SMART SM00418 12 91 1.1E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS24715 d51e0d8471587d5c0df2f448a113aff7 245 Gene3D G3DSA:1.10.10.10 2 98 1.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24715 d51e0d8471587d5c0df2f448a113aff7 245 Pfam PF12840 Helix-turn-helix domain 13 67 2.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24715 d51e0d8471587d5c0df2f448a113aff7 245 SUPERFAMILY SSF46785 6 89 4.59E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24715 d51e0d8471587d5c0df2f448a113aff7 245 Gene3D G3DSA:1.10.10.10 190 245 0.2 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24715 d51e0d8471587d5c0df2f448a113aff7 245 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 1.5E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS24715 d51e0d8471587d5c0df2f448a113aff7 245 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 1.5E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS24715 d51e0d8471587d5c0df2f448a113aff7 245 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 1.5E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS24715 d51e0d8471587d5c0df2f448a113aff7 245 Gene3D G3DSA:1.10.10.10 106 161 0.35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 Gene3D G3DSA:1.10.10.10 1 89 1.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 Gene3D G3DSA:3.40.190.10 182 276 4.1E-24 T 29-03-2018 CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 Gene3D G3DSA:3.40.190.10 91 181 6.7E-20 T 29-03-2018 CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 SUPERFAMILY SSF46785 5 90 1.73E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 SUPERFAMILY SSF53850 90 303 1.01E-37 T 29-03-2018 CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 4.4E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12780 ed749dfa9317199347fe95205c1b4ba2 314 Pfam PF03466 LysR substrate binding domain 89 300 1.5E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS09770 116c355f94f967f2853e0cebc0c5e078 327 SUPERFAMILY SSF53850 127 291 1.09E-14 T 29-03-2018 CVS48_RS09770 116c355f94f967f2853e0cebc0c5e078 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 5.6E-93 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09770 116c355f94f967f2853e0cebc0c5e078 327 PIRSF PIRSF017082 4 327 2.4E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09770 116c355f94f967f2853e0cebc0c5e078 327 Gene3D G3DSA:3.40.190.10 127 257 6.9E-14 T 29-03-2018 CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 SUPERFAMILY SSF51735 1 253 5.39E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 Pfam PF00106 short chain dehydrogenase 8 191 2.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 Gene3D G3DSA:3.40.50.720 1 255 1.4E-53 T 29-03-2018 CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 9.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 9.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS12280 a2dd4eee6a4c07cd7b647e77625bb0a4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS17580 90ef82eab1ade9ac197d6113412fe62b 312 Gene3D G3DSA:3.20.20.70 7 290 4.6E-78 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS17580 90ef82eab1ade9ac197d6113412fe62b 312 Pfam PF00682 HMGL-like 11 283 2.2E-41 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CVS48_RS17580 90ef82eab1ade9ac197d6113412fe62b 312 SUPERFAMILY SSF51569 8 286 8.06E-65 T 29-03-2018 CVS48_RS11010 cdb98d56a0cb54d19e2a20761e33c93b 332 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 64 299 4.8E-55 T 29-03-2018 CVS48_RS11010 cdb98d56a0cb54d19e2a20761e33c93b 332 Gene3D G3DSA:3.40.190.10 56 160 3.5E-5 T 29-03-2018 CVS48_RS11010 cdb98d56a0cb54d19e2a20761e33c93b 332 SUPERFAMILY SSF53850 73 312 3.63E-50 T 29-03-2018 CVS48_RS11010 cdb98d56a0cb54d19e2a20761e33c93b 332 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 49 279 3.0E-64 T 29-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CVS48_RS11010 cdb98d56a0cb54d19e2a20761e33c93b 332 Gene3D G3DSA:3.40.190.10 161 254 1.6E-29 T 29-03-2018 CVS48_RS15395 e552be60e6a9393745e9b581f1c46827 153 SUPERFAMILY SSF89095 5 152 5.75E-36 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CVS48_RS15395 e552be60e6a9393745e9b581f1c46827 153 Gene3D G3DSA:1.10.1510.10 4 93 1.7E-28 T 29-03-2018 CVS48_RS15395 e552be60e6a9393745e9b581f1c46827 153 Pfam PF09424 Yqey-like protein 7 152 1.1E-48 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CVS48_RS15395 e552be60e6a9393745e9b581f1c46827 153 Gene3D G3DSA:1.10.10.410 94 153 7.0E-13 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 SUPERFAMILY SSF52440 8 118 9.5E-32 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 13 403 50.876 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 Pfam PF02222 ATP-grasp domain 129 306 9.1E-52 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 Gene3D G3DSA:3.30.1490.20 135 203 1.6E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 SUPERFAMILY SSF51246 331 402 1.57E-16 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 Pfam PF01370 NAD dependent epimerase/dehydratase family 24 86 6.9E-5 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 SUPERFAMILY SSF56059 119 325 1.94E-55 T 29-03-2018 CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 19 403 4.6E-172 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 Gene3D G3DSA:3.40.50.20 19 118 2.7E-20 T 29-03-2018 CVS48_RS07780 1b804dd6c3ceaf3364228e775aa19be0 405 Gene3D G3DSA:3.30.470.20 204 402 4.2E-38 T 29-03-2018 CVS48_RS27905 783b3fdccae6891d3c114b65edcc72f9 127 SUPERFAMILY SSF81343 11 127 1.47E-24 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27905 783b3fdccae6891d3c114b65edcc72f9 127 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 16 125 1.1E-33 T 29-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 CVS48_RS27905 783b3fdccae6891d3c114b65edcc72f9 127 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 4 114 5.1E-14 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CVS48_RS27905 783b3fdccae6891d3c114b65edcc72f9 127 PIRSF PIRSF000169 8 127 4.4E-38 T 29-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 CVS48_RS27905 783b3fdccae6891d3c114b65edcc72f9 127 Gene3D G3DSA:1.20.1300.10 10 127 1.6E-17 T 29-03-2018 CVS48_RS28025 bdad38ba6ae1cb1f33b29c5c53bcf423 281 Gene3D G3DSA:3.30.1360.130 218 277 6.5E-13 T 29-03-2018 CVS48_RS28025 bdad38ba6ae1cb1f33b29c5c53bcf423 281 PIRSF PIRSF015853 1 281 3.7E-102 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CVS48_RS28025 bdad38ba6ae1cb1f33b29c5c53bcf423 281 Pfam PF04951 D-aminopeptidase 1 271 8.5E-97 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CVS48_RS28025 bdad38ba6ae1cb1f33b29c5c53bcf423 281 Gene3D G3DSA:3.40.50.10780 1 211 4.5E-80 T 29-03-2018 IPR027476 D-aminopeptidase, N-terminal CVS48_RS28025 bdad38ba6ae1cb1f33b29c5c53bcf423 281 SUPERFAMILY SSF63992 1 281 5.1E-101 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CVS48_RS15420 e32a46645cbcf7705d0d0c4716cca352 399 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 70 230 3.6E-19 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CVS48_RS15420 e32a46645cbcf7705d0d0c4716cca352 399 SUPERFAMILY SSF53901 9 231 2.74E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15420 e32a46645cbcf7705d0d0c4716cca352 399 SMART SM00825 Beta-ketoacyl synthase 8 398 8.7E-8 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CVS48_RS15420 e32a46645cbcf7705d0d0c4716cca352 399 SUPERFAMILY SSF53901 204 396 5.46E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15420 e32a46645cbcf7705d0d0c4716cca352 399 Gene3D G3DSA:3.40.47.10 6 242 1.9E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15420 e32a46645cbcf7705d0d0c4716cca352 399 Gene3D G3DSA:3.40.47.10 245 399 7.3E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15420 e32a46645cbcf7705d0d0c4716cca352 399 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 241 340 2.3E-23 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CVS48_RS15420 e32a46645cbcf7705d0d0c4716cca352 399 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 149 165 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CVS48_RS01610 29e9c6d43f3aabe6b7c9c97a6df49f8d 383 Pfam PF13458 Periplasmic binding protein 26 363 1.2E-50 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS01610 29e9c6d43f3aabe6b7c9c97a6df49f8d 383 Gene3D G3DSA:3.40.50.2300 155 281 3.5E-28 T 29-03-2018 CVS48_RS01610 29e9c6d43f3aabe6b7c9c97a6df49f8d 383 Gene3D G3DSA:3.40.50.2300 282 365 2.8E-6 T 29-03-2018 CVS48_RS01610 29e9c6d43f3aabe6b7c9c97a6df49f8d 383 SUPERFAMILY SSF53822 26 382 6.38E-72 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS01610 29e9c6d43f3aabe6b7c9c97a6df49f8d 383 Gene3D G3DSA:3.40.50.2300 24 154 5.1E-11 T 29-03-2018 CVS48_RS25825 b3b791bc983ee69c98456819ac5fb35f 278 Gene3D G3DSA:3.40.50.1820 1 278 5.6E-67 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS25825 b3b791bc983ee69c98456819ac5fb35f 278 SUPERFAMILY SSF53474 2 277 1.28E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS25825 b3b791bc983ee69c98456819ac5fb35f 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 7.7E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS25825 b3b791bc983ee69c98456819ac5fb35f 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 7.7E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS25825 b3b791bc983ee69c98456819ac5fb35f 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 7.7E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS25825 b3b791bc983ee69c98456819ac5fb35f 278 Pfam PF00561 alpha/beta hydrolase fold 24 258 7.6E-24 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS25825 b3b791bc983ee69c98456819ac5fb35f 278 PRINTS PR00412 Epoxide hydrolase signature 29 47 2.8E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS25825 b3b791bc983ee69c98456819ac5fb35f 278 PRINTS PR00412 Epoxide hydrolase signature 49 64 2.8E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS25825 b3b791bc983ee69c98456819ac5fb35f 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 2.8E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 231 1.2E-49 T 29-03-2018 CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 3.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 3.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 3.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 Gene3D G3DSA:3.40.50.720 2 233 7.0E-60 T 29-03-2018 CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.8E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.8E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.8E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20780 f22ca6ad3f5eed35d0254c156f9a4c42 236 SUPERFAMILY SSF51735 5 234 1.85E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS28360 eabe023dc9e5b3e3d36ec71db0494870 215 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 18 214 20.563 T 29-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 CVS48_RS28360 eabe023dc9e5b3e3d36ec71db0494870 215 Pfam PF01794 Ferric reductase like transmembrane component 63 176 1.2E-16 T 29-03-2018 IPR013130 Ferric reductase transmembrane component-like domain CVS48_RS05235 fd94976f419e4ccb4732098bdc46cbce 346 Gene3D G3DSA:3.40.50.2300 147 286 9.1E-20 T 29-03-2018 CVS48_RS05235 fd94976f419e4ccb4732098bdc46cbce 346 Gene3D G3DSA:3.40.50.2300 31 146 2.0E-15 T 29-03-2018 CVS48_RS05235 fd94976f419e4ccb4732098bdc46cbce 346 Pfam PF13407 Periplasmic binding protein domain 33 281 1.5E-41 T 29-03-2018 IPR025997 Periplasmic binding protein CVS48_RS05235 fd94976f419e4ccb4732098bdc46cbce 346 SUPERFAMILY SSF53822 29 289 9.6E-46 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS07065 c322a2416aafe9a536cbe9e027fafef0 349 SUPERFAMILY SSF53448 96 346 1.17E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS07065 c322a2416aafe9a536cbe9e027fafef0 349 SUPERFAMILY SSF54631 6 106 3.79E-18 T 29-03-2018 CVS48_RS07065 c322a2416aafe9a536cbe9e027fafef0 349 Pfam PF00483 Nucleotidyl transferase 123 344 2.4E-33 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CVS48_RS07065 c322a2416aafe9a536cbe9e027fafef0 349 Gene3D G3DSA:3.10.580.10 1 113 2.6E-15 T 29-03-2018 CVS48_RS07065 c322a2416aafe9a536cbe9e027fafef0 349 Pfam PF00571 CBS domain 9 50 2.6E-6 T 29-03-2018 IPR000644 CBS domain CVS48_RS07065 c322a2416aafe9a536cbe9e027fafef0 349 Gene3D G3DSA:3.90.550.10 116 347 2.0E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS19370 91d313bf1921c2635a1b34051cff0290 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 33 54 1.9E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS19370 91d313bf1921c2635a1b34051cff0290 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 64 86 1.9E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS19370 91d313bf1921c2635a1b34051cff0290 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 179 198 1.9E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS19370 91d313bf1921c2635a1b34051cff0290 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 107 132 1.9E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS19370 91d313bf1921c2635a1b34051cff0290 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 1.9E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS19370 91d313bf1921c2635a1b34051cff0290 261 Pfam PF01061 ABC-2 type transporter 14 219 1.8E-19 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 Gene3D G3DSA:3.40.50.1220 194 350 4.5E-35 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 SUPERFAMILY SSF52467 161 360 1.11E-37 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 Gene3D G3DSA:3.40.50.970 351 549 8.1E-43 T 29-03-2018 CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 SUPERFAMILY SSF52518 5 176 1.64E-55 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 Gene3D G3DSA:3.40.50.970 1 193 6.8E-56 T 29-03-2018 CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 SUPERFAMILY SSF52518 368 546 9.65E-62 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 176 2.6E-56 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 535 5.5E-45 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS11440 ff59d1dd95d09fe6b84c2413f346d07e 561 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 330 2.3E-27 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CVS48_RS23680 a241d7c74a966d158dc5a9eb817de3ec 350 Gene3D G3DSA:3.30.460.20 3 164 7.7E-16 T 29-03-2018 CVS48_RS23680 a241d7c74a966d158dc5a9eb817de3ec 350 Gene3D G3DSA:1.20.58.340 284 350 2.8E-17 T 29-03-2018 CVS48_RS23680 a241d7c74a966d158dc5a9eb817de3ec 350 Gene3D G3DSA:1.20.58.340 165 283 3.3E-19 T 29-03-2018 CVS48_RS23680 a241d7c74a966d158dc5a9eb817de3ec 350 Pfam PF01544 CorA-like Mg2+ transporter protein 60 346 1.1E-50 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CVS48_RS23680 a241d7c74a966d158dc5a9eb817de3ec 350 SUPERFAMILY SSF144083 286 347 6.28E-19 T 29-03-2018 CVS48_RS23680 a241d7c74a966d158dc5a9eb817de3ec 350 SUPERFAMILY SSF143865 47 277 9.42E-48 T 29-03-2018 CVS48_RS20280 4f920e7967b39ef711842e9e8ac3e3a3 290 SMART SM00346 40 129 5.0E-6 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS20280 4f920e7967b39ef711842e9e8ac3e3a3 290 Pfam PF01614 Bacterial transcriptional regulator 161 279 1.8E-29 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS20280 4f920e7967b39ef711842e9e8ac3e3a3 290 Pfam PF09339 IclR helix-turn-helix domain 44 90 4.5E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS20280 4f920e7967b39ef711842e9e8ac3e3a3 290 SUPERFAMILY SSF55781 114 282 1.23E-46 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS20280 4f920e7967b39ef711842e9e8ac3e3a3 290 Gene3D G3DSA:3.30.450.40 116 290 1.6E-47 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS20280 4f920e7967b39ef711842e9e8ac3e3a3 290 SUPERFAMILY SSF46785 44 111 4.04E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20280 4f920e7967b39ef711842e9e8ac3e3a3 290 Gene3D G3DSA:1.10.10.10 21 100 3.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13010 2794bef55509547fa47e97310df7de22 378 Pfam PF01702 Queuine tRNA-ribosyltransferase 129 369 4.5E-91 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CVS48_RS13010 2794bef55509547fa47e97310df7de22 378 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 371 6.1E-166 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CVS48_RS13010 2794bef55509547fa47e97310df7de22 378 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 371 8.5E-159 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CVS48_RS13010 2794bef55509547fa47e97310df7de22 378 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 372 55.041 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CVS48_RS13010 2794bef55509547fa47e97310df7de22 378 SUPERFAMILY SSF51713 3 371 8.5E-157 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CVS48_RS13010 2794bef55509547fa47e97310df7de22 378 Gene3D G3DSA:3.20.20.105 1 376 9.5E-156 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CVS48_RS28400 7fd5a2bd7902678f61d291626d9fddc7 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 382 2.6E-47 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS28400 7fd5a2bd7902678f61d291626d9fddc7 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 6 395 51.379 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS28400 7fd5a2bd7902678f61d291626d9fddc7 399 SUPERFAMILY SSF53686 7 393 1.96E-146 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS28400 7fd5a2bd7902678f61d291626d9fddc7 399 PIRSF PIRSF001413 2 399 3.8E-161 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS28400 7fd5a2bd7902678f61d291626d9fddc7 399 Gene3D G3DSA:3.40.50.1100 13 202 1.1E-42 T 29-03-2018 CVS48_RS28400 7fd5a2bd7902678f61d291626d9fddc7 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 85 99 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS28400 7fd5a2bd7902678f61d291626d9fddc7 399 Gene3D G3DSA:3.40.50.1100 203 396 3.3E-38 T 29-03-2018 CVS48_RS28400 7fd5a2bd7902678f61d291626d9fddc7 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 11 394 4.1E-188 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS18265 1a988ae5928905a8fb15bba4cf8209b2 281 Pfam PF00005 ABC transporter 46 195 7.2E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS18265 1a988ae5928905a8fb15bba4cf8209b2 281 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS18265 1a988ae5928905a8fb15bba4cf8209b2 281 SUPERFAMILY SSF52540 14 270 9.37E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18265 1a988ae5928905a8fb15bba4cf8209b2 281 SMART SM00382 55 244 3.5E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS18265 1a988ae5928905a8fb15bba4cf8209b2 281 Gene3D G3DSA:3.40.50.300 19 279 1.2E-74 T 29-03-2018 CVS48_RS24495 432988293431b2e67bca7335c4a35108 164 Pfam PF07471 Phage DNA packaging protein Nu1 70 150 5.0E-15 T 29-03-2018 IPR010906 Bacteriophage lambda, Nu1, terminase small subunit CVS48_RS10545 4b4bf6af94113fa46904f2b3059bb1b3 413 SMART SM00267 213 404 1.4E-39 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS10545 4b4bf6af94113fa46904f2b3059bb1b3 413 Pfam PF00990 Diguanylate cyclase, GGDEF domain 228 333 7.7E-22 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS10545 4b4bf6af94113fa46904f2b3059bb1b3 413 Pfam PF00990 Diguanylate cyclase, GGDEF domain 358 400 1.7E-5 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS10545 4b4bf6af94113fa46904f2b3059bb1b3 413 Gene3D G3DSA:3.30.70.270 222 411 1.6E-46 T 29-03-2018 CVS48_RS10545 4b4bf6af94113fa46904f2b3059bb1b3 413 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 226 335 1.3E-24 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS10545 4b4bf6af94113fa46904f2b3059bb1b3 413 SUPERFAMILY SSF55073 233 405 2.82E-37 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS11385 46902e304e75dcdbc00c906adb1803f1 526 Gene3D G3DSA:2.30.38.10 327 410 1.8E-21 T 29-03-2018 CVS48_RS11385 46902e304e75dcdbc00c906adb1803f1 526 Pfam PF00501 AMP-binding enzyme 22 417 2.8E-81 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS11385 46902e304e75dcdbc00c906adb1803f1 526 Gene3D G3DSA:3.40.50.980 12 180 1.0E-36 T 29-03-2018 CVS48_RS11385 46902e304e75dcdbc00c906adb1803f1 526 SUPERFAMILY SSF56801 14 511 2.88E-129 T 29-03-2018 CVS48_RS11385 46902e304e75dcdbc00c906adb1803f1 526 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 499 3.6E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS11385 46902e304e75dcdbc00c906adb1803f1 526 Gene3D G3DSA:3.30.300.30 411 515 2.7E-21 T 29-03-2018 CVS48_RS11385 46902e304e75dcdbc00c906adb1803f1 526 Gene3D G3DSA:3.40.50.980 181 326 6.2E-34 T 29-03-2018 CVS48_RS11385 46902e304e75dcdbc00c906adb1803f1 526 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 7.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 7.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 7.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 SUPERFAMILY SSF46785 4 84 8.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 Gene3D G3DSA:1.10.10.10 1 84 2.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 Gene3D G3DSA:3.40.190.10 180 257 1.6E-7 T 29-03-2018 CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 SUPERFAMILY SSF53850 94 289 5.25E-23 T 29-03-2018 CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.1E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 Gene3D G3DSA:3.40.190.10 90 179 3.0E-11 T 29-03-2018 CVS48_RS20650 dfc545ed8f2dabb11dce70c49915f03c 298 Pfam PF03466 LysR substrate binding domain 90 282 1.7E-17 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS10850 c64a1481e4e71eee24046d8a8ea89e26 488 Pfam PF00171 Aldehyde dehydrogenase family 20 477 2.2E-173 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS10850 c64a1481e4e71eee24046d8a8ea89e26 488 SUPERFAMILY SSF53720 4 482 3.67E-169 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS10850 c64a1481e4e71eee24046d8a8ea89e26 488 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 9 475 1.9E-211 T 29-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 CVS48_RS10850 c64a1481e4e71eee24046d8a8ea89e26 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS10850 c64a1481e4e71eee24046d8a8ea89e26 488 Gene3D G3DSA:3.40.309.10 266 463 9.0E-71 T 29-03-2018 CVS48_RS10850 c64a1481e4e71eee24046d8a8ea89e26 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS10850 c64a1481e4e71eee24046d8a8ea89e26 488 Gene3D G3DSA:3.40.605.10 4 265 5.6E-100 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS20350 ff6b1c7779ee5b7993d525f6bc0fc306 329 SMART SM00382 36 235 1.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS20350 ff6b1c7779ee5b7993d525f6bc0fc306 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 303 6.9E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS20350 ff6b1c7779ee5b7993d525f6bc0fc306 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 321 4.9E-21 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS20350 ff6b1c7779ee5b7993d525f6bc0fc306 329 Pfam PF00005 ABC transporter 28 185 4.4E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS20350 ff6b1c7779ee5b7993d525f6bc0fc306 329 Gene3D G3DSA:3.40.50.300 4 326 9.8E-68 T 29-03-2018 CVS48_RS20350 ff6b1c7779ee5b7993d525f6bc0fc306 329 SUPERFAMILY SSF52540 7 256 2.87E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS11835 215d92d2891efd337af67bdf8bd763cd 606 SUPERFAMILY SSF48208 196 591 4.76E-109 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CVS48_RS11835 215d92d2891efd337af67bdf8bd763cd 606 Pfam PF00723 Glycosyl hydrolases family 15 219 585 9.4E-68 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CVS48_RS11835 215d92d2891efd337af67bdf8bd763cd 606 Gene3D G3DSA:1.50.10.10 192 552 4.3E-99 T 29-03-2018 CVS48_RS27985 28b7f3f6f62d73075f37862d6f161b34 133 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 35.539 T 29-03-2018 IPR023081 Cell division protein FtsB CVS48_RS27985 28b7f3f6f62d73075f37862d6f161b34 133 Gene3D G3DSA:1.20.5.400 28 72 9.1E-4 T 29-03-2018 CVS48_RS27985 28b7f3f6f62d73075f37862d6f161b34 133 Pfam PF04977 Septum formation initiator 11 88 1.4E-24 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 176 4.5E-4 T 29-03-2018 CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 SUPERFAMILY SSF51735 6 232 3.2E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 6.7E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 6.7E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 6.7E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 230 3.5E-39 T 29-03-2018 CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 Gene3D G3DSA:3.40.50.720 1 234 3.7E-58 T 29-03-2018 CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 1.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13635 4f484a0b7b7865990f40c8848607928b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20635 e445eb73a8d561e62f33789ee86cb60e 326 SUPERFAMILY SSF53850 113 287 1.27E-10 T 29-03-2018 CVS48_RS20635 e445eb73a8d561e62f33789ee86cb60e 326 Gene3D G3DSA:3.40.190.10 144 299 1.0E-10 T 29-03-2018 CVS48_RS20635 e445eb73a8d561e62f33789ee86cb60e 326 PIRSF PIRSF017082 1 325 2.4E-60 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS20635 e445eb73a8d561e62f33789ee86cb60e 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 7.9E-58 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS26970 fc74ddfb33875211c989d6744ffbcd81 325 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 10 317 3.7E-96 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter CVS48_RS26970 fc74ddfb33875211c989d6744ffbcd81 325 PIRSF PIRSF026166 1 325 1.4E-133 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter CVS48_RS20415 da15de8f0cf90e1ae886a2593a57809c 301 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 221 7.7E-20 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CVS48_RS27690 e920d17804119b9034da4ac47e9483b9 335 SUPERFAMILY SSF55174 44 94 6.9E-9 T 29-03-2018 CVS48_RS27690 e920d17804119b9034da4ac47e9483b9 335 SUPERFAMILY SSF55120 103 332 5.96E-64 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS27690 e920d17804119b9034da4ac47e9483b9 335 Gene3D G3DSA:3.30.2350.10 109 334 4.6E-61 T 29-03-2018 CVS48_RS27690 e920d17804119b9034da4ac47e9483b9 335 Gene3D G3DSA:3.10.290.10 31 100 2.7E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS27690 e920d17804119b9034da4ac47e9483b9 335 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 160 174 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS27690 e920d17804119b9034da4ac47e9483b9 335 Pfam PF00849 RNA pseudouridylate synthase 117 274 3.0E-31 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS27690 e920d17804119b9034da4ac47e9483b9 335 Pfam PF01479 S4 domain 44 89 8.3E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS27690 e920d17804119b9034da4ac47e9483b9 335 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 40 329 8.3E-75 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS27935 c50b573d210b706a5393ad8fa47b4443 482 Pfam PF03972 MmgE/PrpD family 18 466 5.2E-164 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CVS48_RS27935 c50b573d210b706a5393ad8fa47b4443 482 Gene3D G3DSA:1.10.4100.10 397 482 4.5E-13 T 29-03-2018 CVS48_RS27935 c50b573d210b706a5393ad8fa47b4443 482 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 481 2.0E-265 T 29-03-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 CVS48_RS27935 c50b573d210b706a5393ad8fa47b4443 482 SUPERFAMILY SSF103378 12 481 1.96E-164 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CVS48_RS27935 c50b573d210b706a5393ad8fa47b4443 482 Gene3D G3DSA:1.10.4100.10 2 331 5.7E-107 T 29-03-2018 CVS48_RS25085 fa5119da8a83b4414e9570d883d88e5c 213 SUPERFAMILY SSF47741 129 210 5.23E-28 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CVS48_RS25085 fa5119da8a83b4414e9570d883d88e5c 213 Pfam PF01799 [2Fe-2S] binding domain 118 205 1.8E-30 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CVS48_RS25085 fa5119da8a83b4414e9570d883d88e5c 213 Gene3D G3DSA:3.10.20.30 43 119 9.1E-29 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS25085 fa5119da8a83b4414e9570d883d88e5c 213 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 84 92 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS25085 fa5119da8a83b4414e9570d883d88e5c 213 SUPERFAMILY SSF54292 46 132 6.82E-27 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS25085 fa5119da8a83b4414e9570d883d88e5c 213 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 52 105 1.5E-8 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS25085 fa5119da8a83b4414e9570d883d88e5c 213 Gene3D G3DSA:1.10.150.120 120 213 2.8E-36 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CVS48_RS23855 5f86df8fa7f2137b353c674ac6e0632a 440 Gene3D G3DSA:2.40.160.60 27 440 4.4E-91 T 29-03-2018 CVS48_RS23855 5f86df8fa7f2137b353c674ac6e0632a 440 SUPERFAMILY SSF56935 27 440 7.94E-95 T 29-03-2018 CVS48_RS23855 5f86df8fa7f2137b353c674ac6e0632a 440 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 20 440 1.8E-108 T 29-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) CVS48_RS00250 73a3490c3fdc6f410742e02c572b212b 208 SUPERFAMILY SSF89392 27 207 1.02E-43 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CVS48_RS00250 73a3490c3fdc6f410742e02c572b212b 208 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 2 205 2.4E-18 T 29-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 CVS48_RS00250 73a3490c3fdc6f410742e02c572b212b 208 Gene3D G3DSA:2.50.20.10 22 208 1.4E-39 T 29-03-2018 CVS48_RS00250 73a3490c3fdc6f410742e02c572b212b 208 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 9 208 28.523 T 29-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 CVS48_RS00250 73a3490c3fdc6f410742e02c572b212b 208 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 36 198 1.4E-43 T 29-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 SMART SM00304 269 320 9.6E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 SUPERFAMILY SSF158472 269 317 3.01E-5 T 29-03-2018 CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 SUPERFAMILY SSF47384 305 375 1.94E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 SUPERFAMILY SSF55874 406 529 1.83E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 Gene3D G3DSA:1.10.287.130 311 375 5.1E-5 T 29-03-2018 CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 528 2.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 509 2.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 471 2.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 Gene3D G3DSA:3.30.565.10 382 533 4.6E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 SMART SM00387 422 531 2.9E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 Pfam PF00672 HAMP domain 269 316 1.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS01445 b055fcf036900f804241a03831f8691e 533 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 530 4.9E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS05320 e0f60d79e6889a5218ebd6cfff8c213d 478 Pfam PF11067 Protein of unknown function (DUF2868) 162 456 8.5E-75 T 29-03-2018 IPR021296 Protein of unknown function DUF2868 CVS48_RS13380 b9415cec7e0bc4e304450bba301150cc 325 Gene3D G3DSA:1.10.3720.10 1 312 6.6E-47 T 29-03-2018 CVS48_RS13380 b9415cec7e0bc4e304450bba301150cc 325 SUPERFAMILY SSF161098 94 308 1.83E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13380 b9415cec7e0bc4e304450bba301150cc 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 323 6.0E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10010 e887a7f19f32fad16557f11e0260dfae 334 Gene3D G3DSA:3.40.50.720 132 302 1.2E-52 T 29-03-2018 CVS48_RS10010 e887a7f19f32fad16557f11e0260dfae 334 SUPERFAMILY SSF52283 50 148 6.97E-5 T 29-03-2018 CVS48_RS10010 e887a7f19f32fad16557f11e0260dfae 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 128 299 8.2E-51 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS10010 e887a7f19f32fad16557f11e0260dfae 334 Gene3D G3DSA:3.40.50.720 28 131 4.2E-8 T 29-03-2018 CVS48_RS10010 e887a7f19f32fad16557f11e0260dfae 334 SUPERFAMILY SSF51735 118 300 7.64E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS03685 e0df8db3bcd8c0ad318c74aee8eb201a 681 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 41 - T 29-03-2018 IPR010916 TonB box, conserved site CVS48_RS03685 e0df8db3bcd8c0ad318c74aee8eb201a 681 Gene3D G3DSA:2.40.170.20 168 681 2.7E-68 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS03685 e0df8db3bcd8c0ad318c74aee8eb201a 681 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 156 2.4E-21 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS03685 e0df8db3bcd8c0ad318c74aee8eb201a 681 Gene3D G3DSA:2.170.130.10 24 163 5.5E-30 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS03685 e0df8db3bcd8c0ad318c74aee8eb201a 681 Pfam PF00593 TonB dependent receptor 259 680 2.6E-49 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS03685 e0df8db3bcd8c0ad318c74aee8eb201a 681 SUPERFAMILY SSF56935 20 681 1.81E-116 T 29-03-2018 CVS48_RS00375 8b9012125109385f7416d9abafe96385 390 Pfam PF05762 VWA domain containing CoxE-like protein 184 269 5.9E-8 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like CVS48_RS25215 3c7c6c0e0ef64fa037d34ba692f82c83 316 SUPERFAMILY SSF51412 2 309 4.43E-64 T 29-03-2018 CVS48_RS25215 3c7c6c0e0ef64fa037d34ba692f82c83 316 Pfam PF03060 Nitronate monooxygenase 5 303 2.5E-61 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CVS48_RS25215 3c7c6c0e0ef64fa037d34ba692f82c83 316 Gene3D G3DSA:3.20.20.70 1 315 5.7E-57 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS01560 7519b2bfe141f87ea5c262732035175f 748 SUPERFAMILY SSF52518 20 200 3.34E-27 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS01560 7519b2bfe141f87ea5c262732035175f 748 SUPERFAMILY SSF52518 410 663 6.88E-32 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS01560 7519b2bfe141f87ea5c262732035175f 748 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 470 614 5.1E-18 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CVS48_RS01560 7519b2bfe141f87ea5c262732035175f 748 Gene3D G3DSA:3.40.50.970 413 617 2.6E-16 T 29-03-2018 CVS48_RS01560 7519b2bfe141f87ea5c262732035175f 748 Gene3D G3DSA:3.40.50.970 23 261 7.3E-17 T 29-03-2018 CVS48_RS01560 7519b2bfe141f87ea5c262732035175f 748 Gene3D G3DSA:3.30.70.20 618 707 3.1E-5 T 29-03-2018 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 SUPERFAMILY SSF56059 511 723 1.75E-44 T 29-03-2018 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 Gene3D G3DSA:3.40.50.261 304 470 7.0E-24 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 Gene3D G3DSA:3.40.50.261 133 302 2.1E-42 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 163 299 2.3E-50 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CVS48_RS09755 4896526bd74763d32d0969596073769a 734 Pfam PF13549 ATP-grasp domain 507 722 2.3E-69 T 29-03-2018 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 SUPERFAMILY SSF52210 307 458 2.35E-23 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 Gene3D G3DSA:3.40.50.720 8 132 9.2E-36 T 29-03-2018 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 Pfam PF13380 CoA binding domain 16 141 3.2E-21 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 Gene3D G3DSA:3.30.470.20 593 723 6.9E-33 T 29-03-2018 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 SUPERFAMILY SSF52210 138 300 4.45E-41 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 Gene3D G3DSA:3.30.1490.20 529 592 3.0E-28 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS09755 4896526bd74763d32d0969596073769a 734 SUPERFAMILY SSF51735 4 145 1.35E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09755 4896526bd74763d32d0969596073769a 734 SMART SM00881 12 107 1.0E-25 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CVS48_RS04570 6bc6edf0c255aa01fe3b0ac01253ebb4 511 SUPERFAMILY SSF56954 4 467 1.96E-55 T 29-03-2018 CVS48_RS04570 6bc6edf0c255aa01fe3b0ac01253ebb4 511 Pfam PF02321 Outer membrane efflux protein 285 459 3.8E-9 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS04570 6bc6edf0c255aa01fe3b0ac01253ebb4 511 Pfam PF02321 Outer membrane efflux protein 53 252 1.0E-20 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS04570 6bc6edf0c255aa01fe3b0ac01253ebb4 511 Gene3D G3DSA:1.20.1600.10 19 466 1.6E-37 T 29-03-2018 CVS48_RS03520 29216e4217666d9519673c5792f366bc 505 SUPERFAMILY SSF51338 7 64 2.4E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS03520 29216e4217666d9519673c5792f366bc 505 SUPERFAMILY SSF51338 423 474 2.4E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS03520 29216e4217666d9519673c5792f366bc 505 Pfam PF07969 Amidohydrolase family 54 203 1.2E-15 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS03520 29216e4217666d9519673c5792f366bc 505 Pfam PF07969 Amidohydrolase family 349 467 4.7E-18 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS03520 29216e4217666d9519673c5792f366bc 505 Gene3D G3DSA:2.30.40.10 9 72 5.5E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS03520 29216e4217666d9519673c5792f366bc 505 Gene3D G3DSA:2.30.40.10 406 481 0.0015 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS03520 29216e4217666d9519673c5792f366bc 505 SUPERFAMILY SSF51556 64 423 8.98E-79 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS03520 29216e4217666d9519673c5792f366bc 505 Gene3D G3DSA:3.20.20.140 73 405 1.7E-68 T 29-03-2018 CVS48_RS11675 06ad7b82cb0cfc469da5473075b8f64d 446 Gene3D G3DSA:1.20.1250.20 235 446 2.5E-23 T 29-03-2018 CVS48_RS11675 06ad7b82cb0cfc469da5473075b8f64d 446 Pfam PF00083 Sugar (and other) transporter 35 244 1.0E-24 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS11675 06ad7b82cb0cfc469da5473075b8f64d 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 141 166 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS11675 06ad7b82cb0cfc469da5473075b8f64d 446 Pfam PF07690 Major Facilitator Superfamily 268 433 4.8E-9 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS11675 06ad7b82cb0cfc469da5473075b8f64d 446 Gene3D G3DSA:1.20.1250.20 16 234 3.3E-23 T 29-03-2018 CVS48_RS11675 06ad7b82cb0cfc469da5473075b8f64d 446 SUPERFAMILY SSF103473 26 438 2.62E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS18920 65e98f27bb21671f6f3c899899a1a3df 159 Gene3D G3DSA:1.20.1290.10 1 151 2.8E-36 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS18920 65e98f27bb21671f6f3c899899a1a3df 159 SUPERFAMILY SSF69118 5 145 2.72E-38 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS18920 65e98f27bb21671f6f3c899899a1a3df 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 94 8.2E-15 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS18920 65e98f27bb21671f6f3c899899a1a3df 159 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 36 78 5.2E-13 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS01150 b572fa93caa3253fe8eee377d9732421 368 Gene3D G3DSA:3.40.50.1220 233 359 1.1E-39 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS01150 b572fa93caa3253fe8eee377d9732421 368 PIRSF PIRSF000089 52 358 6.0E-68 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CVS48_RS01150 b572fa93caa3253fe8eee377d9732421 368 SUPERFAMILY SSF52467 236 352 2.45E-33 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS01150 b572fa93caa3253fe8eee377d9732421 368 Gene3D G3DSA:3.40.50.620 41 232 5.2E-15 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS01150 b572fa93caa3253fe8eee377d9732421 368 Pfam PF01012 Electron transfer flavoprotein domain 57 200 1.7E-12 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS01150 b572fa93caa3253fe8eee377d9732421 368 SUPERFAMILY SSF52402 55 209 4.74E-12 T 29-03-2018 CVS48_RS01150 b572fa93caa3253fe8eee377d9732421 368 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 237 315 2.1E-25 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 Pfam PF03466 LysR substrate binding domain 87 291 4.6E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 Gene3D G3DSA:1.10.10.10 1 81 2.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 SUPERFAMILY SSF53850 87 294 3.14E-38 T 29-03-2018 CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 Gene3D G3DSA:3.40.190.10 82 191 5.0E-19 T 29-03-2018 CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 5.8E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 SUPERFAMILY SSF46785 1 109 3.43E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21535 a3181646fadebf0eb072aec461fbb70d 305 Gene3D G3DSA:3.40.190.10 192 264 1.2E-16 T 29-03-2018 CVS48_RS28870 9f716239844885ac79108549e7ca741f 60 SUPERFAMILY SSF54786 1 60 1.69E-17 T 29-03-2018 CVS48_RS28870 9f716239844885ac79108549e7ca741f 60 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 3 59 3.5E-18 T 29-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 CVS48_RS28870 9f716239844885ac79108549e7ca741f 60 Gene3D G3DSA:3.30.920.30 1 59 2.4E-21 T 29-03-2018 CVS48_RS04190 f546150d4a3e864088e1f768489a9a0a 119 SMART SM00905 6 117 3.0E-31 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CVS48_RS04190 f546150d4a3e864088e1f768489a9a0a 119 SUPERFAMILY SSF55620 3 119 3.06E-29 T 29-03-2018 CVS48_RS04190 f546150d4a3e864088e1f768489a9a0a 119 Gene3D G3DSA:3.30.1130.10 3 119 3.2E-29 T 29-03-2018 CVS48_RS04190 f546150d4a3e864088e1f768489a9a0a 119 Pfam PF02152 Dihydroneopterin aldolase 6 116 3.4E-28 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CVS48_RS04190 f546150d4a3e864088e1f768489a9a0a 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 5 116 3.2E-25 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CVS48_RS04190 f546150d4a3e864088e1f768489a9a0a 119 TIGRFAM TIGR00526 folB_dom: FolB domain 5 116 6.3E-20 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CVS48_RS11485 96663a1ccc19518f45737a0098361b3c 252 Pfam PF07277 SapC 19 235 4.2E-73 T 29-03-2018 IPR010836 SapC CVS48_RS01830 06be3045225c21d60e9bf0a1aeacebd1 232 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 6 207 2.4E-35 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CVS48_RS01830 06be3045225c21d60e9bf0a1aeacebd1 232 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 195 2.2E-38 T 29-03-2018 CVS48_RS01830 06be3045225c21d60e9bf0a1aeacebd1 232 SUPERFAMILY SSF56784 4 225 1.29E-30 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS01830 06be3045225c21d60e9bf0a1aeacebd1 232 Gene3D G3DSA:3.40.50.1000 86 215 1.9E-9 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS01830 06be3045225c21d60e9bf0a1aeacebd1 232 Gene3D G3DSA:1.20.1440.100 19 85 1.5E-23 T 29-03-2018 CVS48_RS01830 06be3045225c21d60e9bf0a1aeacebd1 232 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 197 2.0E-21 T 29-03-2018 CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 Gene3D G3DSA:3.40.50.720 139 346 4.9E-34 T 29-03-2018 CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 252 9.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 9.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 342 359 9.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 321 340 9.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 36 67 4.8E-12 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 SUPERFAMILY SSF50249 37 132 3.6E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 Gene3D G3DSA:3.40.50.720 347 398 0.027 T 29-03-2018 CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 SUPERFAMILY SSF51735 169 394 7.44E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS01595 3f85fe5ebfe2bfd5a8aa88e52bc2bb1f 413 Pfam PF00106 short chain dehydrogenase 171 360 5.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21435 bc05287c3de263470475efec434cfa67 504 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 338 496 7.7E-24 T 29-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain CVS48_RS21435 bc05287c3de263470475efec434cfa67 504 Pfam PF07005 Putative sugar-binding N-terminal domain 43 288 8.7E-46 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CVS48_RS21435 bc05287c3de263470475efec434cfa67 504 SUPERFAMILY SSF142764 43 301 2.35E-74 T 29-03-2018 CVS48_RS21435 bc05287c3de263470475efec434cfa67 504 SUPERFAMILY SSF142764 330 500 2.35E-74 T 29-03-2018 CVS48_RS21435 bc05287c3de263470475efec434cfa67 504 Gene3D G3DSA:3.40.50.10840 41 293 1.8E-47 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CVS48_RS28685 f9ffb1d316ad2950a66288fe145f7975 164 SUPERFAMILY SSF52833 3 158 1.34E-47 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS28685 f9ffb1d316ad2950a66288fe145f7975 164 PIRSF PIRSF000216 2 164 3.8E-54 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28685 f9ffb1d316ad2950a66288fe145f7975 164 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 12 158 3.5E-46 T 29-03-2018 CVS48_RS28685 f9ffb1d316ad2950a66288fe145f7975 164 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 10 158 4.6E-57 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28685 f9ffb1d316ad2950a66288fe145f7975 164 Gene3D G3DSA:3.40.30.10 75 164 1.3E-12 T 29-03-2018 CVS48_RS23230 16a2f7b06d199d9a741c0739ff2f141d 458 Pfam PF07690 Major Facilitator Superfamily 13 377 7.4E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS23230 16a2f7b06d199d9a741c0739ff2f141d 458 Gene3D G3DSA:1.20.1250.20 1 213 4.7E-22 T 29-03-2018 CVS48_RS23230 16a2f7b06d199d9a741c0739ff2f141d 458 Gene3D G3DSA:1.20.1250.20 220 426 1.3E-24 T 29-03-2018 CVS48_RS23230 16a2f7b06d199d9a741c0739ff2f141d 458 SUPERFAMILY SSF103473 2 415 3.14E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS03555 45a8578a52e2f03c310dc7bd2e782e12 250 Pfam PF07072 Cell division protein 16 224 3.3E-72 T 29-03-2018 IPR009777 Cell division protein ZapD CVS48_RS03555 45a8578a52e2f03c310dc7bd2e782e12 250 Gene3D G3DSA:2.60.440.10 172 248 1.0E-29 T 29-03-2018 IPR027462 Z ring-associated protein D, C-terminal domain CVS48_RS03555 45a8578a52e2f03c310dc7bd2e782e12 250 SUPERFAMILY SSF160950 2 248 2.22E-82 T 29-03-2018 IPR009777 Cell division protein ZapD CVS48_RS03555 45a8578a52e2f03c310dc7bd2e782e12 250 Gene3D G3DSA:1.10.3900.10 10 171 1.4E-55 T 29-03-2018 CVS48_RS03555 45a8578a52e2f03c310dc7bd2e782e12 250 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 248 31.163 T 29-03-2018 IPR009777 Cell division protein ZapD CVS48_RS14445 05d1715d174614639619ffa945fdc1dd 224 Gene3D G3DSA:3.40.50.620 42 199 1.1E-4 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS14445 05d1715d174614639619ffa945fdc1dd 224 Pfam PF02677 Uncharacterized BCR, COG1636 18 192 1.5E-64 T 29-03-2018 IPR003828 Probable epoxyqueuosine reductase QueH CVS48_RS03735 4a3bdbd412f4fcb007630a0ad3e8e0eb 215 Pfam PF02036 SCP-2 sterol transfer family 18 115 3.1E-9 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CVS48_RS08585 8cb32334172a6c942332c4f3ecdc7ef1 377 Gene3D G3DSA:3.30.420.10 126 328 1.4E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS08585 8cb32334172a6c942332c4f3ecdc7ef1 377 Pfam PF00665 Integrase core domain 134 257 1.9E-25 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS08585 8cb32334172a6c942332c4f3ecdc7ef1 377 SUPERFAMILY SSF46689 11 115 2.15E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS08585 8cb32334172a6c942332c4f3ecdc7ef1 377 Gene3D G3DSA:1.10.10.10 10 65 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08585 8cb32334172a6c942332c4f3ecdc7ef1 377 SUPERFAMILY SSF53098 130 302 2.4E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS08585 8cb32334172a6c942332c4f3ecdc7ef1 377 Pfam PF13518 Helix-turn-helix domain 12 62 6.5E-12 T 29-03-2018 CVS48_RS26965 675790e45a9490d1df3a2d8ce97a1dfa 326 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 7 324 7.9E-119 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CVS48_RS26965 675790e45a9490d1df3a2d8ce97a1dfa 326 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 3 325 35.799 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CVS48_RS26965 675790e45a9490d1df3a2d8ce97a1dfa 326 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 34 321 4.2E-110 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CVS48_RS26965 675790e45a9490d1df3a2d8ce97a1dfa 326 SUPERFAMILY SSF53659 5 324 5.44E-110 T 29-03-2018 CVS48_RS26965 675790e45a9490d1df3a2d8ce97a1dfa 326 Gene3D G3DSA:3.40.718.10 1 326 6.3E-132 T 29-03-2018 CVS48_RS07985 6ba1bb9bebda42fc63536e84be7c4a9c 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 153 30.266 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CVS48_RS07985 6ba1bb9bebda42fc63536e84be7c4a9c 156 PIRSF PIRSF029256 1 156 3.7E-59 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CVS48_RS07985 6ba1bb9bebda42fc63536e84be7c4a9c 156 SUPERFAMILY SSF75217 1 154 4.12E-41 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CVS48_RS07985 6ba1bb9bebda42fc63536e84be7c4a9c 156 Pfam PF00588 SpoU rRNA Methylase family 2 143 2.0E-32 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CVS48_RS07985 6ba1bb9bebda42fc63536e84be7c4a9c 156 Gene3D G3DSA:3.40.1280.10 1 156 4.2E-39 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 Pfam PF02978 Signal peptide binding domain 341 441 2.1E-31 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 453 33.252 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 Pfam PF00448 SRP54-type protein, GTPase domain 104 308 5.9E-67 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 Gene3D G3DSA:1.20.120.140 223 323 1.1E-33 T 29-03-2018 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 Gene3D G3DSA:3.40.50.300 103 222 1.3E-16 T 29-03-2018 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.6E-19 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 SUPERFAMILY SSF52540 42 370 7.36E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 282 295 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 SUPERFAMILY SSF47446 311 445 1.31E-43 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 Gene3D G3DSA:1.10.260.30 341 446 2.6E-35 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 SMART SM00382 103 283 7.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 Gene3D G3DSA:1.20.120.140 1 90 8.1E-28 T 29-03-2018 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 SMART SM00962 104 309 1.7E-110 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 SMART SM00963 1 86 8.2E-33 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS09845 b3079bd92494f14edf991917a20be4ab 468 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 443 2.7E-169 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CVS48_RS08985 c5f7215e6c8b3aa18d8a6a35dd6069ed 301 SUPERFAMILY SSF103481 203 284 3.14E-6 T 29-03-2018 CVS48_RS08985 c5f7215e6c8b3aa18d8a6a35dd6069ed 301 Pfam PF00892 EamA-like transporter family 154 282 5.7E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS08985 c5f7215e6c8b3aa18d8a6a35dd6069ed 301 SUPERFAMILY SSF103481 52 143 1.96E-6 T 29-03-2018 CVS48_RS15230 2717bf189cd1e8c030b2dd0ca17e8db7 144 SUPERFAMILY SSF55729 8 133 4.82E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS15230 2717bf189cd1e8c030b2dd0ca17e8db7 144 Pfam PF00583 Acetyltransferase (GNAT) family 28 128 1.7E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS15230 2717bf189cd1e8c030b2dd0ca17e8db7 144 Gene3D G3DSA:3.40.630.30 6 141 1.5E-30 T 29-03-2018 CVS48_RS29045 762ff0e91de656e2773672190b5200ec 308 SUPERFAMILY SSF51569 1 282 4.58E-66 T 29-03-2018 CVS48_RS29045 762ff0e91de656e2773672190b5200ec 308 Pfam PF00682 HMGL-like 5 279 4.4E-46 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CVS48_RS29045 762ff0e91de656e2773672190b5200ec 308 Gene3D G3DSA:3.20.20.70 1 296 2.9E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS02530 ff106880691f84aec4c257f60d2494f0 397 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 381 1.4E-113 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS02530 ff106880691f84aec4c257f60d2494f0 397 SUPERFAMILY SSF55031 188 303 1.01E-27 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS02530 ff106880691f84aec4c257f60d2494f0 397 Gene3D G3DSA:3.40.630.10 2 288 9.8E-64 T 29-03-2018 CVS48_RS02530 ff106880691f84aec4c257f60d2494f0 397 Pfam PF01546 Peptidase family M20/M25/M40 78 390 2.4E-34 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS02530 ff106880691f84aec4c257f60d2494f0 397 Pfam PF07687 Peptidase dimerisation domain 190 287 1.1E-8 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS02530 ff106880691f84aec4c257f60d2494f0 397 SUPERFAMILY SSF53187 305 391 1.74E-86 T 29-03-2018 CVS48_RS02530 ff106880691f84aec4c257f60d2494f0 397 SUPERFAMILY SSF53187 7 202 1.74E-86 T 29-03-2018 CVS48_RS02530 ff106880691f84aec4c257f60d2494f0 397 PIRSF PIRSF005962 2 396 2.5E-127 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 Gene3D G3DSA:3.40.50.1260 6 180 3.2E-56 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 SUPERFAMILY SSF53748 15 393 2.36E-141 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 Gene3D G3DSA:3.40.50.1260 181 382 3.4E-79 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PIRSF PIRSF000724 1 397 3.1E-135 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PRINTS PR00477 Phosphoglycerate kinase family signature 15 31 4.6E-80 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PRINTS PR00477 Phosphoglycerate kinase family signature 192 211 4.6E-80 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 4.6E-80 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PRINTS PR00477 Phosphoglycerate kinase family signature 370 387 4.6E-80 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PRINTS PR00477 Phosphoglycerate kinase family signature 37 59 4.6E-80 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PRINTS PR00477 Phosphoglycerate kinase family signature 347 358 4.6E-80 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 4.6E-80 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PRINTS PR00477 Phosphoglycerate kinase family signature 138 160 4.6E-80 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 PRINTS PR00477 Phosphoglycerate kinase family signature 169 191 4.6E-80 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 20 30 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 394 39.373 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS13140 bc2c352bd6576ba579370aa2ff757d40 397 Pfam PF00162 Phosphoglycerate kinase 15 384 9.6E-139 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 236 9.0E-48 T 29-03-2018 CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 5.0E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 5.0E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 5.0E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 SUPERFAMILY SSF51735 7 237 2.35E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 Gene3D G3DSA:3.40.50.720 144 237 2.6E-25 T 29-03-2018 CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 2.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 2.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 2.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 2.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 2.5E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS09215 ab7302c972c941e6ce2f2a8b76b203ae 242 Gene3D G3DSA:3.40.50.720 1 143 2.4E-33 T 29-03-2018 CVS48_RS22000 968023a4f91d7b353635940ecdb0450a 185 Pfam PF06041 Bacterial protein of unknown function (DUF924) 14 182 8.0E-56 T 29-03-2018 IPR010323 Protein of unknown function DUF924 CVS48_RS22000 968023a4f91d7b353635940ecdb0450a 185 Gene3D G3DSA:1.25.40.10 86 184 8.1E-35 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS22000 968023a4f91d7b353635940ecdb0450a 185 Gene3D G3DSA:1.20.58.320 6 85 7.8E-25 T 29-03-2018 CVS48_RS22000 968023a4f91d7b353635940ecdb0450a 185 SUPERFAMILY SSF48452 7 180 2.88E-65 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS20220 cf20baec8df5af9bc54a6192da67408a 130 Gene3D G3DSA:3.30.10.10 75 127 6.5E-4 T 29-03-2018 CVS48_RS20220 cf20baec8df5af9bc54a6192da67408a 130 Pfam PF11720 Peptidase inhibitor I78 family 66 130 5.1E-24 T 29-03-2018 IPR021719 Proteinase inhibitor I78 CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 Gene3D G3DSA:3.30.1330.60 76 215 6.0E-38 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 173 192 2.2E-5 T 29-03-2018 CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 155 172 2.2E-5 T 29-03-2018 CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 193 213 2.2E-5 T 29-03-2018 CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 Pfam PF13441 YMGG-like Gly-zipper 30 71 5.4E-9 T 29-03-2018 IPR027367 YMGG-like Gly-zipper CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 PRINTS PR01021 OMPA domain signature 140 155 2.7E-12 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 PRINTS PR01021 OMPA domain signature 155 171 2.7E-12 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 PRINTS PR01021 OMPA domain signature 110 132 2.7E-12 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 SUPERFAMILY SSF103088 98 210 2.62E-36 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS02055 c4e916e1038bcf2d38a05590a633ff9a 215 Pfam PF00691 OmpA family 110 204 1.4E-19 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS05180 5073c7c904f38e08507d42b27bce98a0 213 SUPERFAMILY SSF50022 43 209 1.21E-40 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS05180 5073c7c904f38e08507d42b27bce98a0 213 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 24 206 4.3E-63 T 29-03-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 CVS48_RS05180 5073c7c904f38e08507d42b27bce98a0 213 Gene3D G3DSA:1.20.5.510 19 47 2.9E-9 T 29-03-2018 CVS48_RS05180 5073c7c904f38e08507d42b27bce98a0 213 Gene3D G3DSA:2.102.10.10 48 213 1.0E-41 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS05180 5073c7c904f38e08507d42b27bce98a0 213 PRINTS PR00162 Rieske 2Fe-2S subunit signature 165 177 9.9E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CVS48_RS05180 5073c7c904f38e08507d42b27bce98a0 213 PRINTS PR00162 Rieske 2Fe-2S subunit signature 178 190 9.9E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CVS48_RS05180 5073c7c904f38e08507d42b27bce98a0 213 PRINTS PR00162 Rieske 2Fe-2S subunit signature 133 144 9.9E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CVS48_RS05180 5073c7c904f38e08507d42b27bce98a0 213 Pfam PF00355 Rieske [2Fe-2S] domain 125 193 2.2E-12 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS22235 371fcf236b0ca2765bdd311f0145eeb8 485 Gene3D G3DSA:3.30.70.1170 131 200 2.1E-16 T 29-03-2018 CVS48_RS22235 371fcf236b0ca2765bdd311f0145eeb8 485 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 191 205 4.1E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS22235 371fcf236b0ca2765bdd311f0145eeb8 485 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 339 355 4.1E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS22235 371fcf236b0ca2765bdd311f0145eeb8 485 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 220 230 4.1E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS22235 371fcf236b0ca2765bdd311f0145eeb8 485 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 393 410 4.1E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS22235 371fcf236b0ca2765bdd311f0145eeb8 485 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 301 4.1E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS22235 371fcf236b0ca2765bdd311f0145eeb8 485 Gene3D G3DSA:3.40.50.150 201 419 4.9E-56 T 29-03-2018 CVS48_RS22235 371fcf236b0ca2765bdd311f0145eeb8 485 Pfam PF01189 16S rRNA methyltransferase RsmB/F 209 408 1.1E-46 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CVS48_RS22235 371fcf236b0ca2765bdd311f0145eeb8 485 SUPERFAMILY SSF53335 106 411 1.25E-66 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS09315 c9f14c0eea78e6c34ab0ca5a0fc91429 411 Pfam PF13458 Periplasmic binding protein 23 372 1.8E-69 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS09315 c9f14c0eea78e6c34ab0ca5a0fc91429 411 Gene3D G3DSA:3.40.50.2300 20 214 4.6E-24 T 29-03-2018 CVS48_RS09315 c9f14c0eea78e6c34ab0ca5a0fc91429 411 SUPERFAMILY SSF53822 23 378 1.21E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS09315 c9f14c0eea78e6c34ab0ca5a0fc91429 411 Gene3D G3DSA:3.40.50.2300 215 367 1.2E-11 T 29-03-2018 CVS48_RS13045 d6789e2cca86de5c5f4302847bb6aa83 277 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 69 265 4.0E-74 T 29-03-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 CVS48_RS13045 d6789e2cca86de5c5f4302847bb6aa83 277 Gene3D G3DSA:1.10.3720.10 25 277 2.3E-30 T 29-03-2018 CVS48_RS13045 d6789e2cca86de5c5f4302847bb6aa83 277 SUPERFAMILY SSF161098 80 263 1.96E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13045 d6789e2cca86de5c5f4302847bb6aa83 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 271 5.5E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS08660 823e42a4794e94e5862b8fdc17ff7a63 491 Gene3D G3DSA:3.40.50.1460 50 285 6.2E-35 T 29-03-2018 CVS48_RS08660 823e42a4794e94e5862b8fdc17ff7a63 491 Gene3D G3DSA:2.60.40.1180 326 440 4.1E-21 T 29-03-2018 CVS48_RS08660 823e42a4794e94e5862b8fdc17ff7a63 491 Pfam PF08238 Sel1 repeat 357 389 8.3E-6 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS08660 823e42a4794e94e5862b8fdc17ff7a63 491 Pfam PF08238 Sel1 repeat 392 426 6.0E-4 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS08660 823e42a4794e94e5862b8fdc17ff7a63 491 SUPERFAMILY SSF52129 49 283 1.2E-34 T 29-03-2018 IPR029030 Caspase-like domain CVS48_RS08660 823e42a4794e94e5862b8fdc17ff7a63 491 Pfam PF00656 Caspase domain 55 275 7.2E-17 T 29-03-2018 CVS48_RS08660 823e42a4794e94e5862b8fdc17ff7a63 491 SMART SM00671 391 426 1.9E-5 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS08660 823e42a4794e94e5862b8fdc17ff7a63 491 SMART SM00671 355 390 4.9E-8 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS08660 823e42a4794e94e5862b8fdc17ff7a63 491 SUPERFAMILY SSF81901 349 434 1.7E-19 T 29-03-2018 CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 Gene3D G3DSA:3.30.70.920 59 148 4.2E-17 T 29-03-2018 CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 SMART SM00344 9 115 4.3E-24 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 SUPERFAMILY SSF46785 8 69 3.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 1.3E-8 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 1.3E-8 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 1.3E-8 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 Pfam PF13404 AsnC-type helix-turn-helix domain 9 50 6.7E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 SUPERFAMILY SSF54909 70 145 4.16E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 Gene3D G3DSA:1.10.10.10 3 58 2.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05575 d95ac32a6d5b3c174c36bd31396d9d7e 158 Pfam PF01037 Lrp/AsnC ligand binding domain 84 142 3.0E-13 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS28245 1741a711a464859eba4c7117ef213612 366 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 360 5.0E-56 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS28245 1741a711a464859eba4c7117ef213612 366 SUPERFAMILY SSF53686 55 361 5.11E-58 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS28245 1741a711a464859eba4c7117ef213612 366 Gene3D G3DSA:3.40.50.1100 75 181 1.5E-22 T 29-03-2018 CVS48_RS28245 1741a711a464859eba4c7117ef213612 366 Gene3D G3DSA:3.40.50.1100 182 366 3.3E-20 T 29-03-2018 CVS48_RS18670 3c1e8054043630d951208ea2d9a1d107 150 Gene3D G3DSA:3.10.450.50 5 147 1.5E-17 T 29-03-2018 CVS48_RS18670 3c1e8054043630d951208ea2d9a1d107 150 Pfam PF13577 SnoaL-like domain 10 139 1.3E-8 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CVS48_RS18670 3c1e8054043630d951208ea2d9a1d107 150 SUPERFAMILY SSF54427 8 142 1.39E-15 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS18145 9cce3e4b8a5215eef8021968f6e2016b 334 SUPERFAMILY SSF53850 41 243 2.61E-9 T 29-03-2018 CVS48_RS18145 9cce3e4b8a5215eef8021968f6e2016b 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 59 330 4.1E-71 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS18145 9cce3e4b8a5215eef8021968f6e2016b 334 Gene3D G3DSA:3.40.190.10 136 275 2.3E-10 T 29-03-2018 CVS48_RS18145 9cce3e4b8a5215eef8021968f6e2016b 334 PIRSF PIRSF017082 2 333 4.5E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11690 afd35ea1bba9ad9b7f993d2aa4c4bf70 169 SUPERFAMILY SSF88659 105 166 4.8E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS11690 afd35ea1bba9ad9b7f993d2aa4c4bf70 169 Gene3D G3DSA:1.10.10.10 79 168 3.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11690 afd35ea1bba9ad9b7f993d2aa4c4bf70 169 SUPERFAMILY SSF88946 9 100 7.06E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS11690 afd35ea1bba9ad9b7f993d2aa4c4bf70 169 Gene3D G3DSA:1.10.1740.10 1 78 1.7E-15 T 29-03-2018 CVS48_RS11690 afd35ea1bba9ad9b7f993d2aa4c4bf70 169 Pfam PF08281 Sigma-70, region 4 112 163 4.2E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS11690 afd35ea1bba9ad9b7f993d2aa4c4bf70 169 Pfam PF04542 Sigma-70 region 2 15 80 3.1E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS11690 afd35ea1bba9ad9b7f993d2aa4c4bf70 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 160 3.8E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS22475 aebdfd4568f24a79e3a3ee114d7f6d2d 254 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 2 244 2.2E-77 T 29-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 CVS48_RS22475 aebdfd4568f24a79e3a3ee114d7f6d2d 254 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 251 39.252 T 29-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 CVS48_RS22475 aebdfd4568f24a79e3a3ee114d7f6d2d 254 Gene3D G3DSA:3.90.550.10 1 254 8.7E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS22475 aebdfd4568f24a79e3a3ee114d7f6d2d 254 Pfam PF02348 Cytidylyltransferase 4 224 4.4E-48 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CVS48_RS22475 aebdfd4568f24a79e3a3ee114d7f6d2d 254 SUPERFAMILY SSF53448 3 249 1.3E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 Gene3D G3DSA:3.40.190.10 95 184 2.0E-20 T 29-03-2018 CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 SUPERFAMILY SSF46785 3 83 1.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 Pfam PF03466 LysR substrate binding domain 96 295 8.7E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 Gene3D G3DSA:3.40.190.10 185 271 2.4E-21 T 29-03-2018 CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 SUPERFAMILY SSF53850 96 302 3.1E-37 T 29-03-2018 CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 4.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 4.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.4E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS06000 0908f0e991f4187d4977a7965db56587 310 Gene3D G3DSA:1.10.10.10 1 91 2.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03645 7a0fd932666c7c75561b52a513d35606 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 202 1.7E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03645 7a0fd932666c7c75561b52a513d35606 219 Gene3D G3DSA:1.10.3720.10 3 219 7.6E-40 T 29-03-2018 CVS48_RS03645 7a0fd932666c7c75561b52a513d35606 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 8.9E-26 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS03645 7a0fd932666c7c75561b52a513d35606 219 SUPERFAMILY SSF161098 13 201 1.28E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27415 910bf4e957e319be3049cd658234de9e 566 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 397 546 3.6E-29 T 29-03-2018 IPR006512 YidE/YbjL duplication CVS48_RS27415 910bf4e957e319be3049cd658234de9e 566 Gene3D G3DSA:3.30.70.1450 217 282 1.3E-5 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS27415 910bf4e957e319be3049cd658234de9e 566 TIGRFAM TIGR03802 Asp_Ala_antiprt: aspartate-alanine antiporter 6 561 3.2E-184 T 29-03-2018 IPR022457 Aspartate-alanine antiporter GO:0005215|GO:0016020 CVS48_RS27415 910bf4e957e319be3049cd658234de9e 566 SUPERFAMILY SSF116726 306 378 1.96E-6 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS27415 910bf4e957e319be3049cd658234de9e 566 Pfam PF06826 Predicted Permease Membrane Region 15 177 2.1E-28 T 29-03-2018 IPR006512 YidE/YbjL duplication CVS48_RS27415 910bf4e957e319be3049cd658234de9e 566 Pfam PF06826 Predicted Permease Membrane Region 390 559 3.9E-34 T 29-03-2018 IPR006512 YidE/YbjL duplication CVS48_RS27415 910bf4e957e319be3049cd658234de9e 566 Gene3D G3DSA:3.30.70.1450 293 383 1.1E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CVS48_RS06770 fb127e5a4f2f3425d30235f46a5411e0 375 Pfam PF01966 HD domain 64 198 4.0E-14 T 29-03-2018 IPR006674 HD domain CVS48_RS06770 fb127e5a4f2f3425d30235f46a5411e0 375 Gene3D G3DSA:1.10.3210.10 15 373 1.0E-82 T 29-03-2018 CVS48_RS06770 fb127e5a4f2f3425d30235f46a5411e0 375 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 4 372 38.406 T 29-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 CVS48_RS06770 fb127e5a4f2f3425d30235f46a5411e0 375 SUPERFAMILY SSF109604 21 372 3.88E-90 T 29-03-2018 CVS48_RS06770 fb127e5a4f2f3425d30235f46a5411e0 375 Pfam PF13286 Phosphohydrolase-associated domain 285 370 2.7E-30 T 29-03-2018 IPR026875 Phosphohydrolase-associated domain CVS48_RS06770 fb127e5a4f2f3425d30235f46a5411e0 375 SMART SM00471 60 208 1.8E-10 T 29-03-2018 IPR003607 HD/PDEase domain CVS48_RS06770 fb127e5a4f2f3425d30235f46a5411e0 375 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 26 168 2.4E-56 T 29-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 CVS48_RS12465 497b7d2d74dff904358193e8086db817 400 SUPERFAMILY SSF47384 197 253 5.1E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS12465 497b7d2d74dff904358193e8086db817 400 SMART SM00387 288 397 1.2E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12465 497b7d2d74dff904358193e8086db817 400 SUPERFAMILY SSF55874 274 395 1.24E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12465 497b7d2d74dff904358193e8086db817 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 394 1.2E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12465 497b7d2d74dff904358193e8086db817 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 341 1.2E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12465 497b7d2d74dff904358193e8086db817 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 375 1.2E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12465 497b7d2d74dff904358193e8086db817 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 396 5.7E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12465 497b7d2d74dff904358193e8086db817 400 Gene3D G3DSA:3.30.565.10 246 398 9.8E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12465 497b7d2d74dff904358193e8086db817 400 Gene3D G3DSA:1.10.287.130 174 245 2.1E-6 T 29-03-2018 CVS48_RS13440 f9d7b50b5252327c6e93b503ace89766 213 Pfam PF01144 Coenzyme A transferase 8 199 1.3E-37 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS13440 f9d7b50b5252327c6e93b503ace89766 213 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 6 210 9.1E-88 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CVS48_RS13440 f9d7b50b5252327c6e93b503ace89766 213 SUPERFAMILY SSF100950 6 211 7.12E-63 T 29-03-2018 CVS48_RS13440 f9d7b50b5252327c6e93b503ace89766 213 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 46 54 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS13440 f9d7b50b5252327c6e93b503ace89766 213 Gene3D G3DSA:3.40.1080.10 5 212 8.0E-57 T 29-03-2018 CVS48_RS13440 f9d7b50b5252327c6e93b503ace89766 213 SMART SM00882 8 205 6.5E-64 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS02920 e63bfc6d1d321b2f04c9912c72132485 233 Gene3D G3DSA:2.60.40.1090 24 232 3.1E-6 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CVS48_RS02920 e63bfc6d1d321b2f04c9912c72132485 233 Pfam PF06551 Protein of unknown function (DUF1120) 26 127 2.4E-13 T 29-03-2018 IPR010546 Protein of unknown function DUF1120 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Pfam PF14252 Domain of unknown function (DUF4347) 91 245 4.7E-44 T 29-03-2018 IPR025592 Domain of unknown function DUF4347 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 SUPERFAMILY SSF103647 2069 2158 5.89E-6 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 SUPERFAMILY SSF103647 1993 2052 9.94E-5 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 SUPERFAMILY SSF49313 2390 2477 5.89E-8 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:4.10.1080.10 657 865 1.2E-7 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:4.10.1080.10 1867 2060 1.1E-8 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:4.10.1080.10 1062 1164 2.9E-9 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:4.10.1080.10 2061 2191 5.6E-12 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:4.10.1080.10 942 1061 6.2E-8 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 SUPERFAMILY SSF50939 1508 1544 2.35E-7 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 SUPERFAMILY SSF50939 1373 1418 2.35E-7 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 SUPERFAMILY SSF50939 1650 1709 2.35E-7 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 4116 4222 1.7E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 4729 4834 4.4E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3301 3406 1.8E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 6563 6668 3.8E-16 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 1766 1866 3.4E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 2689 2794 1.2E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 7290 7380 2.0E-12 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 8400 8506 1.8E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 4024 4115 5.2E-16 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 4639 4728 2.6E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 5046 5137 2.3E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 4932 5038 8.7E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3211 3300 7.2E-16 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 2393 2484 2.5E-18 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 5545 5649 1.6E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 4434 4523 2.8E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 7177 7282 8.6E-17 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 5138 5242 5.0E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 6882 6971 1.5E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 2893 2997 2.4E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3911 4017 1.9E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 4230 4318 1.1E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 7086 7176 3.7E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 6069 6154 2.7E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 4524 4630 5.1E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 2234 2386 0.087 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 5862 5952 1.7E-16 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 7787 7892 1.4E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 1221 1331 1.1E-9 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 5455 5544 1.9E-16 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 2802 2892 1.1E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 2599 2688 4.1E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 8712 8808 1.6E-10 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 5747 5853 3.9E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 2485 2589 2.4E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 6972 7076 1.6E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3618 3707 1.9E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3820 3910 7.5E-16 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 7381 7485 3.9E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 8195 8301 3.1E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 4843 4931 1.4E-16 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3096 3202 7.8E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 1481 1623 0.017 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 5953 6058 9.0E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 8308 8399 7.6E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3505 3610 5.8E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 5339 5445 2.0E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 8602 8711 6.9E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 6271 6359 4.6E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3006 3095 1.1E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 6360 6466 1.4E-12 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3708 3814 1.4E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 7583 7689 7.9E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 556 656 5.1E-12 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 3413 3504 1.8E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 7494 7582 1.3E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 6155 6262 2.2E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 6767 6873 4.2E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.120.640 1637 1760 7.6E-4 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 8513 8601 4.3E-12 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 6673 6766 6.6E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 8101 8194 1.2E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 7989 8089 3.7E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 5654 5746 2.1E-13 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 4319 4417 1.2E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 7897 7988 3.9E-17 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 7694 7786 3.0E-15 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 5246 5338 1.6E-14 T 29-03-2018 CVS48_RS04550 76069f5e08a239a1608ce70bb79bf317 9082 Gene3D G3DSA:2.60.500.10 6470 6562 1.1E-14 T 29-03-2018 CVS48_RS16745 b727fe8dafce227c6a961ea74d554ccf 256 Gene3D G3DSA:3.90.550.10 1 256 1.6E-52 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS16745 b727fe8dafce227c6a961ea74d554ccf 256 Pfam PF00483 Nucleotidyl transferase 2 200 9.2E-20 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CVS48_RS16745 b727fe8dafce227c6a961ea74d554ccf 256 SUPERFAMILY SSF53448 1 256 1.28E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS16745 b727fe8dafce227c6a961ea74d554ccf 256 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 256 6.0E-144 T 29-03-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 CVS48_RS19360 dfffcf70a3cf37bf4a7434a3967615dc 1168 Gene3D G3DSA:3.40.50.1000 500 661 4.7E-11 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS19360 dfffcf70a3cf37bf4a7434a3967615dc 1168 SUPERFAMILY SSF56784 441 641 8.48E-17 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 SMART SM01209 203 336 0.0035 T 29-03-2018 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 Pfam PF02222 ATP-grasp domain 213 286 1.0E-6 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 SUPERFAMILY SSF53244 711 838 1.08E-23 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 Gene3D G3DSA:3.40.1190.10 467 713 1.5E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 Gene3D G3DSA:3.90.190.20 714 854 1.7E-21 T 29-03-2018 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 Gene3D G3DSA:3.30.470.20 274 454 1.3E-24 T 29-03-2018 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 SUPERFAMILY SSF56059 204 334 4.07E-37 T 29-03-2018 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 SUPERFAMILY SSF56059 370 459 4.07E-37 T 29-03-2018 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 Pfam PF02875 Mur ligase family, glutamate ligase domain 711 785 1.3E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 473 496 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 SUPERFAMILY SSF53623 433 724 4.97E-41 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 2 853 0.0 T 29-03-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 Gene3D G3DSA:3.30.1490.20 185 273 1.3E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS27625 e32802ac57fa71fe8da8e1706fb9fd79 856 Pfam PF08245 Mur ligase middle domain 475 686 3.1E-20 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CVS48_RS04040 c42a7ce124fbcb3a43f177ff0983566f 325 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 5 322 42.142 T 29-03-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 CVS48_RS04040 c42a7ce124fbcb3a43f177ff0983566f 325 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 7 323 5.1E-144 T 29-03-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 CVS48_RS04040 c42a7ce124fbcb3a43f177ff0983566f 325 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 239 271 8.0E-16 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS04040 c42a7ce124fbcb3a43f177ff0983566f 325 Gene3D G3DSA:3.30.60.70 117 157 7.7E-16 T 29-03-2018 CVS48_RS04040 c42a7ce124fbcb3a43f177ff0983566f 325 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 117 157 1.5E-15 T 29-03-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 CVS48_RS04040 c42a7ce124fbcb3a43f177ff0983566f 325 Gene3D G3DSA:2.160.10.10 158 320 7.5E-19 T 29-03-2018 CVS48_RS04040 c42a7ce124fbcb3a43f177ff0983566f 325 SUPERFAMILY SSF51161 78 304 8.73E-39 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS01545 b99b9fed1fbd54851a5cbc8570f047da 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 1.1E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS01545 b99b9fed1fbd54851a5cbc8570f047da 329 SUPERFAMILY SSF161098 92 304 6.76E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS01545 b99b9fed1fbd54851a5cbc8570f047da 329 Gene3D G3DSA:1.10.3720.10 3 308 1.0E-40 T 29-03-2018 CVS48_RS03195 df3f04aed1c1ece24eae49adef27a099 177 ProSitePatterns PS00194 Thioredoxin family active site. 68 86 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CVS48_RS03195 df3f04aed1c1ece24eae49adef27a099 177 Pfam PF08534 Redoxin 47 164 4.0E-16 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CVS48_RS03195 df3f04aed1c1ece24eae49adef27a099 177 Gene3D G3DSA:3.40.30.10 19 177 1.0E-28 T 29-03-2018 CVS48_RS03195 df3f04aed1c1ece24eae49adef27a099 177 SUPERFAMILY SSF52833 1 172 4.05E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS20455 6ccbad2e40a26b0c58daba47ce84c1ba 274 Gene3D G3DSA:1.10.10.60 224 274 5.5E-12 T 29-03-2018 CVS48_RS20455 6ccbad2e40a26b0c58daba47ce84c1ba 274 SMART SM00342 187 269 2.6E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS20455 6ccbad2e40a26b0c58daba47ce84c1ba 274 Pfam PF02311 AraC-like ligand binding domain 24 151 1.6E-24 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CVS48_RS20455 6ccbad2e40a26b0c58daba47ce84c1ba 274 Gene3D G3DSA:2.60.120.10 5 178 4.4E-6 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS20455 6ccbad2e40a26b0c58daba47ce84c1ba 274 SUPERFAMILY SSF46689 171 220 9.86E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS20455 6ccbad2e40a26b0c58daba47ce84c1ba 274 SUPERFAMILY SSF46689 223 272 5.82E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS20455 6ccbad2e40a26b0c58daba47ce84c1ba 274 SUPERFAMILY SSF51215 35 153 4.05E-20 T 29-03-2018 CVS48_RS20455 6ccbad2e40a26b0c58daba47ce84c1ba 274 Pfam PF12833 Helix-turn-helix domain 193 271 7.2E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS20455 6ccbad2e40a26b0c58daba47ce84c1ba 274 Gene3D G3DSA:1.10.10.60 179 223 1.3E-11 T 29-03-2018 CVS48_RS13860 e4c23c244e7208bfca3016da6b230340 281 Pfam PF00809 Pterin binding enzyme 20 259 7.1E-85 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS13860 e4c23c244e7208bfca3016da6b230340 281 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 19 273 3.3E-99 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CVS48_RS13860 e4c23c244e7208bfca3016da6b230340 281 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 53 66 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS13860 e4c23c244e7208bfca3016da6b230340 281 Gene3D G3DSA:3.20.20.20 2 278 2.2E-108 T 29-03-2018 CVS48_RS13860 e4c23c244e7208bfca3016da6b230340 281 SUPERFAMILY SSF51717 6 274 3.4E-99 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS13860 e4c23c244e7208bfca3016da6b230340 281 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 19 34 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CVS48_RS01710 1df89787e33757aef1eac3f6414175e1 401 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 48 269 1.1E-12 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS01710 1df89787e33757aef1eac3f6414175e1 401 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 383 6.3E-47 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS01710 1df89787e33757aef1eac3f6414175e1 401 Gene3D G3DSA:1.20.1600.10 34 392 3.4E-32 T 29-03-2018 CVS48_RS01710 1df89787e33757aef1eac3f6414175e1 401 SUPERFAMILY SSF111369 55 262 2.75E-23 T 29-03-2018 CVS48_RS02895 a726b91e996ddeccd7cb4112b9e6dfd4 235 SUPERFAMILY SSF49354 23 140 4.71E-22 T 29-03-2018 IPR008962 PapD-like CVS48_RS02895 a726b91e996ddeccd7cb4112b9e6dfd4 235 Gene3D G3DSA:2.60.40.10 28 142 9.1E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS02895 a726b91e996ddeccd7cb4112b9e6dfd4 235 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 28 141 8.4E-18 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 CVS48_RS02895 a726b91e996ddeccd7cb4112b9e6dfd4 235 Gene3D G3DSA:2.60.40.10 143 229 1.5E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS02895 a726b91e996ddeccd7cb4112b9e6dfd4 235 SUPERFAMILY SSF49584 145 227 7.33E-8 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal CVS48_RS02895 a726b91e996ddeccd7cb4112b9e6dfd4 235 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 162 223 4.7E-5 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal CVS48_RS09045 c4bdc22886cc500f29f3424afbb63e38 254 SMART SM00382 35 215 2.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS09045 c4bdc22886cc500f29f3424afbb63e38 254 Pfam PF00005 ABC transporter 27 166 1.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS09045 c4bdc22886cc500f29f3424afbb63e38 254 Gene3D G3DSA:3.40.50.300 5 224 6.1E-61 T 29-03-2018 CVS48_RS09045 c4bdc22886cc500f29f3424afbb63e38 254 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS09045 c4bdc22886cc500f29f3424afbb63e38 254 SUPERFAMILY SSF52540 10 221 1.01E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27020 5d137d0cd4e47d57a07e88d18bcf614a 303 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 92 108 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CVS48_RS27020 5d137d0cd4e47d57a07e88d18bcf614a 303 Pfam PF00348 Polyprenyl synthetase 37 268 1.0E-52 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CVS48_RS27020 5d137d0cd4e47d57a07e88d18bcf614a 303 SUPERFAMILY SSF48576 8 295 1.28E-81 T 29-03-2018 IPR008949 Isoprenoid synthase domain CVS48_RS27020 5d137d0cd4e47d57a07e88d18bcf614a 303 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 222 234 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CVS48_RS27020 5d137d0cd4e47d57a07e88d18bcf614a 303 Gene3D G3DSA:1.10.600.10 1 303 7.1E-82 T 29-03-2018 IPR008949 Isoprenoid synthase domain CVS48_RS09810 4ae8f23391fc8834f2d042e2fce7e4a8 217 Pfam PF01081 KDPG and KHG aldolase 10 189 6.7E-29 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CVS48_RS09810 4ae8f23391fc8834f2d042e2fce7e4a8 217 Gene3D G3DSA:3.20.20.70 4 211 6.8E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS09810 4ae8f23391fc8834f2d042e2fce7e4a8 217 SUPERFAMILY SSF51569 4 208 1.48E-56 T 29-03-2018 CVS48_RS14915 3b3fdb60a693620f457c5f678059d613 648 SUPERFAMILY SSF55073 242 396 1.1E-12 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS14915 3b3fdb60a693620f457c5f678059d613 648 Gene3D G3DSA:3.30.70.270 229 401 7.5E-21 T 29-03-2018 CVS48_RS14915 3b3fdb60a693620f457c5f678059d613 648 Pfam PF00563 EAL domain 416 638 1.7E-22 T 29-03-2018 IPR001633 EAL domain CVS48_RS14915 3b3fdb60a693620f457c5f678059d613 648 SMART SM00052 409 642 1.4E-6 T 29-03-2018 IPR001633 EAL domain CVS48_RS14915 3b3fdb60a693620f457c5f678059d613 648 Gene3D G3DSA:3.20.20.450 402 646 4.7E-28 T 29-03-2018 IPR001633 EAL domain CVS48_RS14915 3b3fdb60a693620f457c5f678059d613 648 Pfam PF16448 LapD/MoxY periplasmic domain 24 145 8.0E-40 T 29-03-2018 IPR032244 LapD/MoxY, periplasmic domain CVS48_RS14915 3b3fdb60a693620f457c5f678059d613 648 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 352 3.9E-11 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS14915 3b3fdb60a693620f457c5f678059d613 648 SUPERFAMILY SSF141868 415 639 2.09E-24 T 29-03-2018 IPR001633 EAL domain CVS48_RS14915 3b3fdb60a693620f457c5f678059d613 648 SMART SM00267 225 397 1.9E-6 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS10810 001ab824b214e7448cd1ccac570fa0bc 72 Pfam PF10932 Protein of unknown function (DUF2783) 3 61 3.2E-29 T 29-03-2018 IPR021233 Protein of unknown function DUF2783 CVS48_RS02310 9d87a1957388fbfd7aabf7f22e665b67 939 SMART SM00869 662 929 6.1E-47 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS02310 9d87a1957388fbfd7aabf7f22e665b67 939 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 339 370 9.3E-6 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CVS48_RS02310 9d87a1957388fbfd7aabf7f22e665b67 939 SUPERFAMILY SSF103515 606 939 3.53E-62 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS02310 9d87a1957388fbfd7aabf7f22e665b67 939 Gene3D G3DSA:2.40.128.130 597 939 1.3E-59 T 29-03-2018 CVS48_RS02310 9d87a1957388fbfd7aabf7f22e665b67 939 SUPERFAMILY SSF51126 108 487 5.34E-19 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS02310 9d87a1957388fbfd7aabf7f22e665b67 939 Pfam PF03797 Autotransporter beta-domain 665 919 1.7E-59 T 29-03-2018 IPR005546 Autotransporter beta-domain CVS48_RS02310 9d87a1957388fbfd7aabf7f22e665b67 939 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 409 939 1.2E-44 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 CVS48_RS22470 46ce9f9e4a04280870f52fcd71512ab1 59 SUPERFAMILY SSF158997 1 55 1.57E-20 T 29-03-2018 CVS48_RS22470 46ce9f9e4a04280870f52fcd71512ab1 59 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 27.867 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 CVS48_RS22470 46ce9f9e4a04280870f52fcd71512ab1 59 Gene3D G3DSA:2.20.25.10 8 59 9.8E-21 T 29-03-2018 CVS48_RS22470 46ce9f9e4a04280870f52fcd71512ab1 59 Pfam PF03966 Trm112p-like protein 4 41 1.2E-11 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 CVS48_RS25440 2f5a975b7e867d17c35994a628b0fc3b 176 Pfam PF10722 Putative bacterial sensory transduction regulator 12 130 7.8E-8 T 29-03-2018 IPR019660 Putative sensory transduction regulator YbjN CVS48_RS19465 dd72dc7c4bbedf976e08c7c289bafcbb 311 Pfam PF03466 LysR substrate binding domain 101 298 3.2E-19 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS19465 dd72dc7c4bbedf976e08c7c289bafcbb 311 Gene3D G3DSA:3.40.190.10 191 270 8.6E-7 T 29-03-2018 CVS48_RS19465 dd72dc7c4bbedf976e08c7c289bafcbb 311 SUPERFAMILY SSF46785 11 119 6.53E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19465 dd72dc7c4bbedf976e08c7c289bafcbb 311 Gene3D G3DSA:1.10.10.10 7 93 2.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19465 dd72dc7c4bbedf976e08c7c289bafcbb 311 Gene3D G3DSA:3.40.190.10 99 190 1.8E-10 T 29-03-2018 CVS48_RS19465 dd72dc7c4bbedf976e08c7c289bafcbb 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 72 3.2E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS19465 dd72dc7c4bbedf976e08c7c289bafcbb 311 SUPERFAMILY SSF53850 102 300 3.44E-23 T 29-03-2018 CVS48_RS06880 41b30464a071de3b953646a314d4137b 130 Gene3D G3DSA:1.10.10.10 17 122 0.016 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS06880 41b30464a071de3b953646a314d4137b 130 Pfam PF13663 Domain of unknown function (DUF4148) 1 54 8.5E-13 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS06880 41b30464a071de3b953646a314d4137b 130 Pfam PF13663 Domain of unknown function (DUF4148) 94 126 6.8E-6 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS06880 41b30464a071de3b953646a314d4137b 130 Pfam PF13663 Domain of unknown function (DUF4148) 59 89 1.1E-6 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS12050 80739af2c87ae4ba85af803405f946e3 269 Gene3D G3DSA:3.20.20.450 118 257 0.01 T 29-03-2018 IPR001633 EAL domain CVS48_RS08580 3203ee8406dec17658548eda7c9d0af9 494 ProSitePatterns PS01130 SLC26A transporters signature. 44 65 - T 29-03-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 CVS48_RS08580 3203ee8406dec17658548eda7c9d0af9 494 Gene3D G3DSA:3.30.750.24 388 483 3.5E-15 T 29-03-2018 IPR002645 STAS domain CVS48_RS08580 3203ee8406dec17658548eda7c9d0af9 494 SUPERFAMILY SSF52091 395 480 7.65E-11 T 29-03-2018 IPR002645 STAS domain CVS48_RS08580 3203ee8406dec17658548eda7c9d0af9 494 Pfam PF00916 Sulfate permease family 17 145 3.0E-25 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CVS48_RS08580 3203ee8406dec17658548eda7c9d0af9 494 Pfam PF00916 Sulfate permease family 148 342 3.7E-28 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CVS48_RS08580 3203ee8406dec17658548eda7c9d0af9 494 Pfam PF01740 STAS domain 403 475 7.1E-7 T 29-03-2018 IPR002645 STAS domain CVS48_RS02900 ab2a6298fec16004f211d68eac101738 811 SUPERFAMILY SSF141729 36 147 1.7E-10 T 29-03-2018 CVS48_RS02900 ab2a6298fec16004f211d68eac101738 811 Pfam PF13953 PapC C-terminal domain 730 792 1.1E-8 T 29-03-2018 IPR025949 PapC-like, C-terminal domain CVS48_RS02900 ab2a6298fec16004f211d68eac101738 811 Pfam PF00577 Outer membrane usher protein 184 721 4.8E-81 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 CVS48_RS02900 ab2a6298fec16004f211d68eac101738 811 Pfam PF13954 PapC N-terminal domain 36 167 1.8E-15 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 CVS48_RS24345 6c8ad6380be00802f5992e27a0dc71d2 259 Pfam PF00877 NlpC/P60 family 124 254 4.8E-13 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CVS48_RS24345 6c8ad6380be00802f5992e27a0dc71d2 259 Pfam PF14464 Prokaryotic homologs of the JAB domain 4 98 1.7E-17 T 29-03-2018 IPR028090 JAB domain, prokaryotic CVS48_RS24345 6c8ad6380be00802f5992e27a0dc71d2 259 Gene3D G3DSA:3.90.1720.10 104 259 3.0E-11 T 29-03-2018 CVS48_RS24345 6c8ad6380be00802f5992e27a0dc71d2 259 SUPERFAMILY SSF102712 2 102 3.14E-21 T 29-03-2018 CVS48_RS24345 6c8ad6380be00802f5992e27a0dc71d2 259 SUPERFAMILY SSF54001 116 256 7.85E-12 T 29-03-2018 CVS48_RS24345 6c8ad6380be00802f5992e27a0dc71d2 259 Gene3D G3DSA:3.40.140.10 1 103 2.1E-11 T 29-03-2018 CVS48_RS04200 68c0bfd224009b4c38cb18bc498f12cb 322 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 175 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CVS48_RS04200 68c0bfd224009b4c38cb18bc498f12cb 322 Gene3D G3DSA:3.40.50.720 119 287 4.4E-51 T 29-03-2018 CVS48_RS04200 68c0bfd224009b4c38cb18bc498f12cb 322 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 286 4.1E-53 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS04200 68c0bfd224009b4c38cb18bc498f12cb 322 Gene3D G3DSA:3.40.50.720 1 118 5.2E-30 T 29-03-2018 CVS48_RS04200 68c0bfd224009b4c38cb18bc498f12cb 322 SUPERFAMILY SSF51735 107 286 1.41E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS04200 68c0bfd224009b4c38cb18bc498f12cb 322 SUPERFAMILY SSF52283 2 127 5.53E-23 T 29-03-2018 CVS48_RS04200 68c0bfd224009b4c38cb18bc498f12cb 322 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 312 1.2E-13 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CVS48_RS05790 b592bba2148c11972e0769d494d3fbe8 195 Gene3D G3DSA:2.30.110.10 8 194 3.5E-50 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS05790 b592bba2148c11972e0769d494d3fbe8 195 SMART SM00903 14 160 6.4E-34 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS05790 b592bba2148c11972e0769d494d3fbe8 195 SUPERFAMILY SSF50475 2 182 6.38E-45 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS05790 b592bba2148c11972e0769d494d3fbe8 195 Pfam PF01613 Flavin reductase like domain 19 152 3.3E-24 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS17860 ea4c245629a1b804ef4f56093c61bdcc 394 Pfam PF01070 FMN-dependent dehydrogenase 18 381 2.6E-119 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CVS48_RS17860 ea4c245629a1b804ef4f56093c61bdcc 394 PIRSF PIRSF000138 1 386 1.2E-122 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CVS48_RS17860 ea4c245629a1b804ef4f56093c61bdcc 394 SUPERFAMILY SSF51395 8 198 7.33E-86 T 29-03-2018 CVS48_RS17860 ea4c245629a1b804ef4f56093c61bdcc 394 SUPERFAMILY SSF51395 231 381 7.33E-86 T 29-03-2018 CVS48_RS17860 ea4c245629a1b804ef4f56093c61bdcc 394 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 280 286 - T 29-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CVS48_RS17860 ea4c245629a1b804ef4f56093c61bdcc 394 Gene3D G3DSA:3.20.20.70 7 385 1.0E-87 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS25530 5d3ded157a6f4dc2755c82cef641de27 440 Pfam PF08378 Nuclease-related domain 54 170 1.0E-9 T 29-03-2018 IPR011528 Nuclease-related domain, NERD CVS48_RS25530 5d3ded157a6f4dc2755c82cef641de27 440 SUPERFAMILY SSF50249 359 431 5.06E-7 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS25530 5d3ded157a6f4dc2755c82cef641de27 440 Gene3D G3DSA:2.40.50.140 358 436 1.8E-7 T 29-03-2018 CVS48_RS22635 65b5fb1fd5408dc5f108f19f94f03aea 440 Pfam PF01593 Flavin containing amine oxidoreductase 11 435 2.2E-26 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CVS48_RS22635 65b5fb1fd5408dc5f108f19f94f03aea 440 Gene3D G3DSA:3.50.50.60 1 438 9.0E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS22635 65b5fb1fd5408dc5f108f19f94f03aea 440 SUPERFAMILY SSF51905 396 435 4.1E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS22635 65b5fb1fd5408dc5f108f19f94f03aea 440 SUPERFAMILY SSF51905 2 300 4.1E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS22635 65b5fb1fd5408dc5f108f19f94f03aea 440 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 4 434 8.5E-113 T 29-03-2018 IPR017830 Squalene-associated FAD-dependent desaturase CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 Gene3D G3DSA:3.90.380.10 163 422 9.4E-46 T 29-03-2018 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 Pfam PF00355 Rieske [2Fe-2S] domain 54 137 1.9E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 97 120 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 SUPERFAMILY SSF55961 184 420 2.04E-46 T 29-03-2018 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 Gene3D G3DSA:2.102.10.10 49 162 3.6E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 SUPERFAMILY SSF50022 21 175 3.4E-44 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 210 420 4.3E-17 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 159 185 2.3E-23 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 90 110 2.3E-23 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 69 84 2.3E-23 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 111 131 2.3E-23 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS18685 0a73bbcef47919cab9d94e04cd11c14f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 198 220 2.3E-23 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS21240 4a172e5bc89055e9fb04af7e44d60634 361 Pfam PF02353 Mycolic acid cyclopropane synthetase 80 343 2.1E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS21240 4a172e5bc89055e9fb04af7e44d60634 361 Gene3D G3DSA:3.40.50.150 75 356 3.9E-42 T 29-03-2018 CVS48_RS21240 4a172e5bc89055e9fb04af7e44d60634 361 SUPERFAMILY SSF53335 83 354 3.68E-55 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS01975 a8495c675e13968933c4738755d7162a 131 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CVS48_RS01975 a8495c675e13968933c4738755d7162a 131 SUPERFAMILY SSF54593 1 128 2.69E-38 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS01975 a8495c675e13968933c4738755d7162a 131 Gene3D G3DSA:3.10.180.10 1 131 5.8E-39 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS01975 a8495c675e13968933c4738755d7162a 131 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 129 2.4E-67 T 29-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CVS48_RS01975 a8495c675e13968933c4738755d7162a 131 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CVS48_RS01975 a8495c675e13968933c4738755d7162a 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 5.8E-25 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS17540 eb810017343afb3eef9c40234c1502be 167 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 44 165 6.1E-51 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS17540 eb810017343afb3eef9c40234c1502be 167 Gene3D G3DSA:2.170.150.20 33 167 2.3E-58 T 29-03-2018 CVS48_RS17540 eb810017343afb3eef9c40234c1502be 167 SUPERFAMILY SSF51316 43 165 1.31E-56 T 29-03-2018 IPR011057 Mss4-like CVS48_RS17540 eb810017343afb3eef9c40234c1502be 167 Pfam PF01641 SelR domain 47 164 1.0E-50 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CVS48_RS24225 e4e4f9b9af5478098b90642e7afa2acf 301 SUPERFAMILY SSF74650 13 290 8.16E-48 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CVS48_RS24225 e4e4f9b9af5478098b90642e7afa2acf 301 Pfam PF01263 Aldose 1-epimerase 65 288 6.8E-28 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CVS48_RS24225 e4e4f9b9af5478098b90642e7afa2acf 301 Gene3D G3DSA:2.70.98.10 12 296 9.7E-51 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CVS48_RS07850 e4feffd6ceda7e255b1820911a12f39c 322 Gene3D G3DSA:3.40.190.10 121 230 7.0E-14 T 29-03-2018 CVS48_RS07850 e4feffd6ceda7e255b1820911a12f39c 322 SUPERFAMILY SSF53850 113 282 5.1E-14 T 29-03-2018 CVS48_RS07850 e4feffd6ceda7e255b1820911a12f39c 322 PIRSF PIRSF017082 1 321 1.8E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS07850 e4feffd6ceda7e255b1820911a12f39c 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 2.8E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22765 2ad276d2ac50db03dbe9a9abb209d14a 766 Pfam PF06761 Intracellular multiplication and human macrophage-killing 70 374 1.8E-66 T 29-03-2018 IPR009612 ImcF-related CVS48_RS22765 2ad276d2ac50db03dbe9a9abb209d14a 766 Pfam PF06744 Type VI secretion protein IcmF C-terminal 463 658 1.3E-50 T 29-03-2018 IPR010623 Type VI secretion system IcmF, C-terminal CVS48_RS21835 a9b7b30bf616952e64a55b79b3e9cfc6 384 Pfam PF00108 Thiolase, N-terminal domain 5 252 9.6E-58 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS21835 a9b7b30bf616952e64a55b79b3e9cfc6 384 ProSitePatterns PS00737 Thiolases signature 2. 330 346 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CVS48_RS21835 a9b7b30bf616952e64a55b79b3e9cfc6 384 Gene3D G3DSA:3.40.47.10 1 255 3.6E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS21835 a9b7b30bf616952e64a55b79b3e9cfc6 384 Gene3D G3DSA:3.40.47.10 256 384 3.5E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS21835 a9b7b30bf616952e64a55b79b3e9cfc6 384 PIRSF PIRSF000429 1 384 2.8E-106 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS21835 a9b7b30bf616952e64a55b79b3e9cfc6 384 SUPERFAMILY SSF53901 215 383 2.01E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS21835 a9b7b30bf616952e64a55b79b3e9cfc6 384 SUPERFAMILY SSF53901 3 124 2.01E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS21835 a9b7b30bf616952e64a55b79b3e9cfc6 384 Pfam PF02803 Thiolase, C-terminal domain 262 383 2.6E-34 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CVS48_RS21835 a9b7b30bf616952e64a55b79b3e9cfc6 384 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 382 8.0E-114 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS04055 0bc409913628d72629ef1184969d0c03 342 Gene3D G3DSA:3.90.1150.10 247 342 9.0E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS04055 0bc409913628d72629ef1184969d0c03 342 Gene3D G3DSA:3.40.640.10 12 246 5.8E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS04055 0bc409913628d72629ef1184969d0c03 342 Pfam PF01212 Beta-eliminating lyase 3 287 5.7E-59 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CVS48_RS04055 0bc409913628d72629ef1184969d0c03 342 SUPERFAMILY SSF53383 1 339 5.19E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS04055 0bc409913628d72629ef1184969d0c03 342 PIRSF PIRSF038940 1 342 1.5E-163 T 29-03-2018 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 CVS48_RS15560 82f8a8ea44b730f6bd2f96fe2a9fa722 397 Gene3D G3DSA:1.20.1250.20 2 188 6.1E-23 T 29-03-2018 CVS48_RS15560 82f8a8ea44b730f6bd2f96fe2a9fa722 397 Gene3D G3DSA:1.20.1250.20 193 390 1.8E-10 T 29-03-2018 CVS48_RS15560 82f8a8ea44b730f6bd2f96fe2a9fa722 397 SUPERFAMILY SSF103473 5 383 7.85E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS15560 82f8a8ea44b730f6bd2f96fe2a9fa722 397 Pfam PF07690 Major Facilitator Superfamily 11 268 2.5E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS11895 acbac4b18c685710de2e8ff7321500e6 88 Gene3D G3DSA:1.10.260.40 13 86 3.1E-11 T 29-03-2018 CVS48_RS11895 acbac4b18c685710de2e8ff7321500e6 88 SMART SM00530 19 73 2.1E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS11895 acbac4b18c685710de2e8ff7321500e6 88 Pfam PF01381 Helix-turn-helix 22 68 8.2E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS11895 acbac4b18c685710de2e8ff7321500e6 88 SUPERFAMILY SSF47413 10 72 1.34E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS20290 6dec02532249fb70a1c8ef40104be5c4 446 Gene3D G3DSA:1.20.1250.20 238 436 4.6E-19 T 29-03-2018 CVS48_RS20290 6dec02532249fb70a1c8ef40104be5c4 446 Pfam PF07690 Major Facilitator Superfamily 253 430 3.6E-14 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS20290 6dec02532249fb70a1c8ef40104be5c4 446 Pfam PF00083 Sugar (and other) transporter 13 225 2.1E-22 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS20290 6dec02532249fb70a1c8ef40104be5c4 446 Gene3D G3DSA:1.20.1250.20 9 226 1.7E-24 T 29-03-2018 CVS48_RS20290 6dec02532249fb70a1c8ef40104be5c4 446 SUPERFAMILY SSF103473 1 426 1.03E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS12375 bff3670a3bfa55b4f517325177ad1eea 297 Pfam PF00892 EamA-like transporter family 1 136 4.1E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS12375 bff3670a3bfa55b4f517325177ad1eea 297 Pfam PF00892 EamA-like transporter family 149 281 2.0E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS12375 bff3670a3bfa55b4f517325177ad1eea 297 SUPERFAMILY SSF103481 190 284 7.06E-11 T 29-03-2018 CVS48_RS12375 bff3670a3bfa55b4f517325177ad1eea 297 SUPERFAMILY SSF103481 36 139 1.57E-14 T 29-03-2018 CVS48_RS11570 703785564aa11bc2c33afba49c720eda 315 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 40 311 6.6E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11570 703785564aa11bc2c33afba49c720eda 315 SUPERFAMILY SSF53850 103 280 6.51E-11 T 29-03-2018 CVS48_RS11570 703785564aa11bc2c33afba49c720eda 315 PIRSF PIRSF017082 1 315 4.7E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11570 703785564aa11bc2c33afba49c720eda 315 Gene3D G3DSA:3.40.190.10 115 245 2.6E-10 T 29-03-2018 CVS48_RS19200 d74638e47915caba3f82b74c667224aa 246 SUPERFAMILY SSF46785 3 74 5.18E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19200 d74638e47915caba3f82b74c667224aa 246 Pfam PF09339 IclR helix-turn-helix domain 6 53 2.0E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS19200 d74638e47915caba3f82b74c667224aa 246 Gene3D G3DSA:1.10.10.10 1 63 5.4E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19200 d74638e47915caba3f82b74c667224aa 246 SUPERFAMILY SSF55781 76 243 2.09E-37 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS19200 d74638e47915caba3f82b74c667224aa 246 Gene3D G3DSA:3.30.450.40 68 244 1.0E-36 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS19200 d74638e47915caba3f82b74c667224aa 246 SMART SM00346 3 93 0.0045 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS19200 d74638e47915caba3f82b74c667224aa 246 Pfam PF01614 Bacterial transcriptional regulator 125 242 2.5E-21 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS05780 64c85b89c43f64ef437ef45cc136b5e1 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 6.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS05780 64c85b89c43f64ef437ef45cc136b5e1 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 6.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS05780 64c85b89c43f64ef437ef45cc136b5e1 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 6.2E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS05780 64c85b89c43f64ef437ef45cc136b5e1 219 SUPERFAMILY SSF46689 10 86 3.34E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS05780 64c85b89c43f64ef437ef45cc136b5e1 219 Gene3D G3DSA:1.10.357.10 6 219 6.5E-36 T 29-03-2018 CVS48_RS25860 6113671e6d98e44ebb2ba91561879371 482 Gene3D G3DSA:3.40.309.10 268 455 2.4E-60 T 29-03-2018 CVS48_RS25860 6113671e6d98e44ebb2ba91561879371 482 Gene3D G3DSA:3.40.605.10 1 267 1.1E-75 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS25860 6113671e6d98e44ebb2ba91561879371 482 Pfam PF00171 Aldehyde dehydrogenase family 17 471 2.5E-132 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS25860 6113671e6d98e44ebb2ba91561879371 482 SUPERFAMILY SSF53720 2 475 2.09E-138 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS25860 6113671e6d98e44ebb2ba91561879371 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS03010 3a0bdbaef51b8c52f8d00953f4748920 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CVS48_RS03010 3a0bdbaef51b8c52f8d00953f4748920 130 SUPERFAMILY SSF54211 5 130 4.55E-46 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CVS48_RS03010 3a0bdbaef51b8c52f8d00953f4748920 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 31.298 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CVS48_RS03010 3a0bdbaef51b8c52f8d00953f4748920 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 2.6E-45 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CVS48_RS03010 3a0bdbaef51b8c52f8d00953f4748920 130 Gene3D G3DSA:3.30.230.10 4 130 6.7E-51 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 SUPERFAMILY SSF46548 2 154 2.28E-41 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 Gene3D G3DSA:3.40.50.720 144 249 1.5E-20 T 29-03-2018 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 Gene3D G3DSA:3.50.50.60 250 333 6.7E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 Gene3D G3DSA:3.50.50.60 334 414 5.4E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 2.4E-26 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 469 1.4E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 SUPERFAMILY SSF51971 142 414 1.65E-63 T 29-03-2018 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 4.4E-226 T 29-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 SUPERFAMILY SSF51971 371 481 6.47E-12 T 29-03-2018 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 9.3E-21 T 29-03-2018 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 9.3E-21 T 29-03-2018 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 9.3E-21 T 29-03-2018 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 Gene3D G3DSA:3.50.50.60 417 488 2.6E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05020 ae5da16bc4b9021664621f3b994022d3 488 Gene3D G3DSA:1.10.1060.10 6 143 3.3E-43 T 29-03-2018 CVS48_RS21545 e38001037c29e951979ddd3816ec5e02 254 Gene3D G3DSA:3.50.30.40 52 227 2.9E-46 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS21545 e38001037c29e951979ddd3816ec5e02 254 Pfam PF03737 Aldolase/RraA 72 207 1.3E-31 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS21545 e38001037c29e951979ddd3816ec5e02 254 SUPERFAMILY SSF89562 55 216 3.79E-41 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS07325 5c1ca8f17e574eeed2e7f5590714843f 439 SUPERFAMILY SSF103473 28 438 1.96E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS07325 5c1ca8f17e574eeed2e7f5590714843f 439 ProSitePatterns PS00217 Sugar transport proteins signature 2. 139 164 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS07325 5c1ca8f17e574eeed2e7f5590714843f 439 Pfam PF07690 Major Facilitator Superfamily 39 382 1.2E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS07325 5c1ca8f17e574eeed2e7f5590714843f 439 ProSitePatterns PS00216 Sugar transport proteins signature 1. 89 105 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS07325 5c1ca8f17e574eeed2e7f5590714843f 439 Gene3D G3DSA:1.20.1250.20 235 439 2.6E-27 T 29-03-2018 CVS48_RS07325 5c1ca8f17e574eeed2e7f5590714843f 439 Gene3D G3DSA:1.20.1250.20 19 234 1.6E-26 T 29-03-2018 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.348 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 Pfam PF00164 Ribosomal protein S12/S23 15 123 3.6E-43 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 3.0E-69 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.1E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.1E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.1E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.1E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.1E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.1E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 SUPERFAMILY SSF50249 2 124 1.29E-52 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 Gene3D G3DSA:2.40.50.140 1 125 8.3E-65 T 29-03-2018 CVS48_RS06320 b4927f9ef75b6cea3c5c5f0877090e41 125 PIRSF PIRSF002133 1 124 4.2E-55 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 202 446 3.6E-87 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 PIRSF PIRSF000185 22 448 6.2E-115 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 SUPERFAMILY SSF51735 202 448 2.6E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 Gene3D G3DSA:1.10.285.10 374 448 2.6E-29 T 29-03-2018 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 Gene3D G3DSA:1.10.285.10 6 63 4.7E-8 T 29-03-2018 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 Gene3D G3DSA:3.40.50.10860 64 190 3.5E-54 T 29-03-2018 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 SMART SM00839 204 446 7.0E-95 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 SUPERFAMILY SSF53223 7 196 4.16E-73 T 29-03-2018 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 184 1.9E-49 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 193 215 6.5E-31 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 6.5E-31 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 6.5E-31 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 235 255 6.5E-31 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 Gene3D G3DSA:3.40.50.720 209 373 1.6E-43 T 29-03-2018 CVS48_RS07595 4a9e16820af208baee79ca2cb2d4b0ae 448 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 122 135 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CVS48_RS05060 3119554104853dd123d394057fff26e8 165 Pfam PF02470 MlaD protein 39 116 6.4E-22 T 29-03-2018 IPR003399 Mce/MlaD CVS48_RS05060 3119554104853dd123d394057fff26e8 165 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 146 1.6E-58 T 29-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 CVS48_RS20950 df97bc58d735966d3e31e939a44ca415 126 Pfam PF04134 Protein of unknown function, DUF393 8 112 2.4E-10 T 29-03-2018 IPR007263 Protein of unknown function DUF393 CVS48_RS05680 c4ef9c025eca76b4a16df7e5331bfb87 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 216 1.9E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05680 c4ef9c025eca76b4a16df7e5331bfb87 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 111 4.4E-28 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS05680 c4ef9c025eca76b4a16df7e5331bfb87 222 SUPERFAMILY SSF161098 15 205 8.83E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05680 c4ef9c025eca76b4a16df7e5331bfb87 222 Gene3D G3DSA:1.10.3720.10 2 222 1.7E-35 T 29-03-2018 CVS48_RS03650 471569006386133e2551cc25ab1d609b 221 Gene3D G3DSA:1.10.3720.10 2 220 1.6E-41 T 29-03-2018 CVS48_RS03650 471569006386133e2551cc25ab1d609b 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 215 1.8E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03650 471569006386133e2551cc25ab1d609b 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 2.2E-23 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS03650 471569006386133e2551cc25ab1d609b 221 SUPERFAMILY SSF161098 13 214 4.32E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS07080 bd66ecb3cf941325077694adb53e55b5 389 Gene3D G3DSA:3.40.50.2000 210 351 2.5E-26 T 29-03-2018 CVS48_RS07080 bd66ecb3cf941325077694adb53e55b5 389 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 6 370 2.9E-141 T 29-03-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-4085001 CVS48_RS07080 bd66ecb3cf941325077694adb53e55b5 389 SUPERFAMILY SSF53756 5 373 1.15E-93 T 29-03-2018 CVS48_RS07080 bd66ecb3cf941325077694adb53e55b5 389 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 372 2.1E-92 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CVS48_RS07080 bd66ecb3cf941325077694adb53e55b5 389 Gene3D G3DSA:3.40.50.2000 2 209 2.8E-52 T 29-03-2018 CVS48_RS14965 b4ce8d2bd29de851de389133bbd5698e 216 Pfam PF00694 Aconitase C-terminal domain 1 132 6.9E-38 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS14965 b4ce8d2bd29de851de389133bbd5698e 216 Gene3D G3DSA:3.20.19.10 1 184 2.8E-46 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS14965 b4ce8d2bd29de851de389133bbd5698e 216 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 42.892 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CVS48_RS14965 b4ce8d2bd29de851de389133bbd5698e 216 SUPERFAMILY SSF52016 1 201 1.24E-60 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS14965 b4ce8d2bd29de851de389133bbd5698e 216 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 1.2E-80 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CVS48_RS00820 1aa69aaef97423234b04bce5b956a667 229 Pfam PF11679 Protein of unknown function (DUF3275) 14 222 6.2E-96 T 29-03-2018 IPR021693 Protein of unknown function DUF3275 CVS48_RS12150 23506e9b6e8952eedcc974338c8bca39 297 Gene3D G3DSA:3.40.190.10 181 260 2.9E-7 T 29-03-2018 CVS48_RS12150 23506e9b6e8952eedcc974338c8bca39 297 Gene3D G3DSA:1.10.10.10 1 85 2.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12150 23506e9b6e8952eedcc974338c8bca39 297 SUPERFAMILY SSF46785 2 84 3.13E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12150 23506e9b6e8952eedcc974338c8bca39 297 Pfam PF03466 LysR substrate binding domain 94 293 1.3E-16 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS12150 23506e9b6e8952eedcc974338c8bca39 297 SUPERFAMILY SSF53850 93 292 2.71E-18 T 29-03-2018 CVS48_RS12150 23506e9b6e8952eedcc974338c8bca39 297 Gene3D G3DSA:3.40.190.10 93 180 4.3E-4 T 29-03-2018 CVS48_RS12150 23506e9b6e8952eedcc974338c8bca39 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.4E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17880 c4a3aba0038063364adf4f938c4aac3f 278 SUPERFAMILY SSF53850 35 257 6.26E-39 T 29-03-2018 CVS48_RS17880 c4a3aba0038063364adf4f938c4aac3f 278 SMART SM00062 39 261 1.4E-25 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS17880 c4a3aba0038063364adf4f938c4aac3f 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 251 7.2E-33 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS17880 c4a3aba0038063364adf4f938c4aac3f 278 Gene3D G3DSA:3.40.190.10 139 260 3.5E-16 T 29-03-2018 CVS48_RS17880 c4a3aba0038063364adf4f938c4aac3f 278 Gene3D G3DSA:3.40.190.10 30 138 1.1E-13 T 29-03-2018 CVS48_RS14485 115edd6a952292a9adb62d0b57a2c108 417 Pfam PF04235 Protein of unknown function (DUF418) 235 395 2.8E-43 T 29-03-2018 IPR007349 Domain of unknown function DUF418 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 Gene3D G3DSA:3.30.420.40 257 322 1.9E-10 T 29-03-2018 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 1.5E-153 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 9.0E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 9.0E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 9.0E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 9.0E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 9.0E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 Gene3D G3DSA:3.30.420.40 8 173 1.5E-38 T 29-03-2018 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 Pfam PF06723 MreB/Mbl protein 11 340 3.3E-147 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 SUPERFAMILY SSF53067 9 153 4.65E-37 T 29-03-2018 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 Gene3D G3DSA:3.90.640.10 191 256 3.3E-26 T 29-03-2018 CVS48_RS07630 11ba214a7eea254b1954721903313e4d 347 SUPERFAMILY SSF53067 156 337 8.96E-49 T 29-03-2018 CVS48_RS13875 f346eebc157f98a89eca86eeecd4af50 495 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 5 303 1.7E-97 T 29-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 CVS48_RS13875 f346eebc157f98a89eca86eeecd4af50 495 Gene3D G3DSA:3.30.420.150 122 302 2.5E-34 T 29-03-2018 CVS48_RS13875 f346eebc157f98a89eca86eeecd4af50 495 Gene3D G3DSA:3.30.420.40 1 121 1.1E-39 T 29-03-2018 CVS48_RS13875 f346eebc157f98a89eca86eeecd4af50 495 SUPERFAMILY SSF109604 310 491 1.63E-40 T 29-03-2018 CVS48_RS13875 f346eebc157f98a89eca86eeecd4af50 495 PIRSF PIRSF001267 1 494 3.6E-188 T 29-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 CVS48_RS13875 f346eebc157f98a89eca86eeecd4af50 495 SUPERFAMILY SSF53067 5 130 2.36E-34 T 29-03-2018 CVS48_RS13875 f346eebc157f98a89eca86eeecd4af50 495 Pfam PF02541 Ppx/GppA phosphatase family 28 304 3.2E-73 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CVS48_RS13875 f346eebc157f98a89eca86eeecd4af50 495 SUPERFAMILY SSF53067 134 305 5.61E-42 T 29-03-2018 CVS48_RS15590 336aee87b843e5c1f6fb9510ea28df48 887 PIRSF PIRSF000156 1 886 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CVS48_RS15590 336aee87b843e5c1f6fb9510ea28df48 887 SUPERFAMILY SSF52518 58 465 2.78E-119 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS15590 336aee87b843e5c1f6fb9510ea28df48 887 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 8 883 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CVS48_RS15590 336aee87b843e5c1f6fb9510ea28df48 887 SUPERFAMILY SSF52518 472 698 1.01E-93 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS15590 336aee87b843e5c1f6fb9510ea28df48 887 Gene3D G3DSA:3.40.50.970 470 704 1.3E-62 T 29-03-2018 CVS48_RS15590 336aee87b843e5c1f6fb9510ea28df48 887 Gene3D G3DSA:3.40.50.970 57 468 1.3E-75 T 29-03-2018 CVS48_RS15590 336aee87b843e5c1f6fb9510ea28df48 887 Gene3D G3DSA:3.40.50.920 705 886 4.0E-37 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS15590 336aee87b843e5c1f6fb9510ea28df48 887 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 204 294 1.3E-4 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS15590 336aee87b843e5c1f6fb9510ea28df48 887 SUPERFAMILY SSF52922 700 882 1.45E-56 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 Gene3D G3DSA:1.10.10.10 4 77 9.1E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 SMART SM00345 16 75 4.0E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 Pfam PF07729 FCD domain 105 226 1.0E-25 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 SUPERFAMILY SSF48008 104 235 5.49E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 SUPERFAMILY SSF46785 7 79 5.06E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 3.9E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 3.9E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 2.0E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 Gene3D G3DSA:1.20.120.530 99 244 6.0E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS15100 3e32ace0ac97a138a8c162204b5db7df 247 SMART SM00895 105 228 1.1E-21 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS13260 251dd156f33cf5c209e5e524988dd1f4 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 263 4.6E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13260 251dd156f33cf5c209e5e524988dd1f4 264 Gene3D G3DSA:1.10.3720.10 16 264 1.2E-29 T 29-03-2018 CVS48_RS13260 251dd156f33cf5c209e5e524988dd1f4 264 SUPERFAMILY SSF161098 67 257 5.36E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13260 251dd156f33cf5c209e5e524988dd1f4 264 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 19 263 1.1E-92 T 29-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CVS48_RS03420 9aa02035f31e232b77711f4f85a5555c 285 Pfam PF00378 Enoyl-CoA hydratase/isomerase 34 284 1.1E-39 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS03420 9aa02035f31e232b77711f4f85a5555c 285 Gene3D G3DSA:1.10.12.10 243 285 1.8E-12 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS03420 9aa02035f31e232b77711f4f85a5555c 285 Gene3D G3DSA:3.90.226.10 28 242 7.4E-57 T 29-03-2018 CVS48_RS03420 9aa02035f31e232b77711f4f85a5555c 285 SUPERFAMILY SSF52096 19 284 1.01E-72 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS03420 9aa02035f31e232b77711f4f85a5555c 285 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 125 145 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS24995 ed1029216d8d01bcf209f2da81b6b2e0 433 SUPERFAMILY SSF103473 4 420 1.18E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS24995 ed1029216d8d01bcf209f2da81b6b2e0 433 Gene3D G3DSA:1.20.1250.20 213 421 1.2E-20 T 29-03-2018 CVS48_RS24995 ed1029216d8d01bcf209f2da81b6b2e0 433 Pfam PF07690 Major Facilitator Superfamily 14 370 4.7E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS24995 ed1029216d8d01bcf209f2da81b6b2e0 433 Gene3D G3DSA:1.20.1250.20 2 204 1.6E-20 T 29-03-2018 CVS48_RS00365 4b2bff9e9238a2471f60b4f7e895ee37 117 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 45 112 3.7E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS00365 4b2bff9e9238a2471f60b4f7e895ee37 117 SUPERFAMILY SSF46626 13 117 5.82E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS00365 4b2bff9e9238a2471f60b4f7e895ee37 117 Gene3D G3DSA:1.10.760.10 7 116 7.4E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS13895 aa41c64ae5e956ebcebe772fa588dfce 285 Gene3D G3DSA:1.10.3720.10 10 280 5.1E-38 T 29-03-2018 CVS48_RS13895 aa41c64ae5e956ebcebe772fa588dfce 285 SUPERFAMILY SSF161098 30 278 1.44E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13895 aa41c64ae5e956ebcebe772fa588dfce 285 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 21 282 1.1E-83 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CVS48_RS13895 aa41c64ae5e956ebcebe772fa588dfce 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 281 1.6E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03290 af35ac0664b08c419f467bd454eae294 405 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 241 254 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CVS48_RS03290 af35ac0664b08c419f467bd454eae294 405 Pfam PF00155 Aminotransferase class I and II 37 397 7.4E-66 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS03290 af35ac0664b08c419f467bd454eae294 405 Gene3D G3DSA:3.90.1150.10 280 405 3.0E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS03290 af35ac0664b08c419f467bd454eae294 405 Gene3D G3DSA:3.40.640.10 50 279 1.9E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS03290 af35ac0664b08c419f467bd454eae294 405 SUPERFAMILY SSF53383 8 401 2.34E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS18795 0b4a3f58ff4d17e94d4d1ab518f99838 197 Gene3D G3DSA:3.40.50.150 5 189 6.7E-26 T 29-03-2018 CVS48_RS18795 0b4a3f58ff4d17e94d4d1ab518f99838 197 SUPERFAMILY SSF53335 13 160 7.0E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS18795 0b4a3f58ff4d17e94d4d1ab518f99838 197 Pfam PF05401 Nodulation protein S (NodS) 17 148 6.4E-14 T 29-03-2018 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 SMART SM00347 34 134 2.6E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 Pfam PF12802 MarR family 42 98 1.5E-11 T 29-03-2018 CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 Gene3D G3DSA:1.10.10.10 5 139 7.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.6E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.6E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.6E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 Gene3D G3DSA:3.40.630.30 140 320 5.1E-18 T 29-03-2018 CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 SUPERFAMILY SSF46785 13 150 3.64E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 Pfam PF00583 Acetyltransferase (GNAT) family 197 297 6.5E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS12020 0363c2660353d314266fdd1d5b0eedc5 322 SUPERFAMILY SSF55729 176 306 1.52E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS14230 f15a10ce6441dad6c929620cbccdde2c 74 Gene3D G3DSA:2.30.30.320 1 72 2.9E-17 T 29-03-2018 IPR023387 DUF1653-like domain CVS48_RS14230 f15a10ce6441dad6c929620cbccdde2c 74 Pfam PF07866 Protein of unknown function (DUF1653) 12 68 8.4E-19 T 29-03-2018 IPR023387 DUF1653-like domain CVS48_RS17750 9b98ad04d0d320968dff7d478d457f82 229 SUPERFAMILY SSF46785 9 80 6.06E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17750 9b98ad04d0d320968dff7d478d457f82 229 Gene3D G3DSA:1.10.10.10 1 72 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17750 9b98ad04d0d320968dff7d478d457f82 229 SMART SM00345 18 76 3.5E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS17750 9b98ad04d0d320968dff7d478d457f82 229 Gene3D G3DSA:1.20.120.530 73 229 9.8E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS17750 9b98ad04d0d320968dff7d478d457f82 229 SUPERFAMILY SSF48008 85 217 8.63E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS17750 9b98ad04d0d320968dff7d478d457f82 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 76 6.7E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS17750 9b98ad04d0d320968dff7d478d457f82 229 Pfam PF07729 FCD domain 90 208 2.6E-19 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS17750 9b98ad04d0d320968dff7d478d457f82 229 SMART SM00895 86 210 1.1E-10 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS21750 4fc006a8db97f8853a1a2f102832287a 309 SUPERFAMILY SSF81345 2 305 6.41E-54 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CVS48_RS21750 4fc006a8db97f8853a1a2f102832287a 309 Gene3D G3DSA:1.10.3470.10 2 309 6.3E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS21750 4fc006a8db97f8853a1a2f102832287a 309 Pfam PF01032 FecCD transport family 20 305 6.1E-52 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CVS48_RS25670 8131dcf68d0ed6e01cc019d4927b7326 353 Gene3D G3DSA:3.40.50.2000 6 167 8.0E-26 T 29-03-2018 CVS48_RS25670 8131dcf68d0ed6e01cc019d4927b7326 353 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 88 327 6.5E-28 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CVS48_RS25670 8131dcf68d0ed6e01cc019d4927b7326 353 Gene3D G3DSA:3.40.50.2000 170 351 8.6E-43 T 29-03-2018 CVS48_RS25670 8131dcf68d0ed6e01cc019d4927b7326 353 SUPERFAMILY SSF53756 13 349 5.96E-72 T 29-03-2018 CVS48_RS21190 b521642caec55436b4de81e50f5639f7 160 Gene3D G3DSA:3.40.140.10 3 158 3.2E-22 T 29-03-2018 CVS48_RS21190 b521642caec55436b4de81e50f5639f7 160 SUPERFAMILY SSF53927 3 112 7.23E-29 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CVS48_RS21190 b521642caec55436b4de81e50f5639f7 160 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 103 1.3E-10 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CVS48_RS28185 a789c55a084ae49f1c463aca91595ed7 497 Gene3D G3DSA:3.40.605.10 1 265 8.8E-86 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS28185 a789c55a084ae49f1c463aca91595ed7 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 483 1.7E-211 T 29-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CVS48_RS28185 a789c55a084ae49f1c463aca91595ed7 497 Pfam PF00171 Aldehyde dehydrogenase family 17 479 9.3E-135 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS28185 a789c55a084ae49f1c463aca91595ed7 497 SUPERFAMILY SSF53720 4 483 4.71E-143 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS28185 a789c55a084ae49f1c463aca91595ed7 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS28185 a789c55a084ae49f1c463aca91595ed7 497 Gene3D G3DSA:3.40.309.10 266 461 1.1E-60 T 29-03-2018 CVS48_RS24215 0db0cfa2d66d678a00b8a95d968c3826 337 SMART SM00829 16 334 4.9E-11 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS24215 0db0cfa2d66d678a00b8a95d968c3826 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 90 1.7E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS24215 0db0cfa2d66d678a00b8a95d968c3826 337 Pfam PF13602 Zinc-binding dehydrogenase 194 334 6.8E-20 T 29-03-2018 CVS48_RS24215 0db0cfa2d66d678a00b8a95d968c3826 337 SUPERFAMILY SSF51735 117 287 6.41E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS24215 0db0cfa2d66d678a00b8a95d968c3826 337 Gene3D G3DSA:3.90.180.10 1 137 1.1E-30 T 29-03-2018 CVS48_RS24215 0db0cfa2d66d678a00b8a95d968c3826 337 Gene3D G3DSA:3.40.50.720 138 301 4.3E-25 T 29-03-2018 CVS48_RS24215 0db0cfa2d66d678a00b8a95d968c3826 337 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 337 3.4E-167 T 29-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 CVS48_RS24215 0db0cfa2d66d678a00b8a95d968c3826 337 SUPERFAMILY SSF50129 15 144 1.0E-32 T 29-03-2018 IPR011032 GroES-like CVS48_RS09395 5496acc14bba61dae548ade6fffe52a6 450 SUPERFAMILY SSF51905 369 422 2.06E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09395 5496acc14bba61dae548ade6fffe52a6 450 SUPERFAMILY SSF51905 8 197 2.06E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09395 5496acc14bba61dae548ade6fffe52a6 450 Pfam PF12831 FAD dependent oxidoreductase 17 439 4.3E-110 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09395 5496acc14bba61dae548ade6fffe52a6 450 Gene3D G3DSA:3.50.50.60 15 421 2.3E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09395 5496acc14bba61dae548ade6fffe52a6 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 351 4.4E-7 T 29-03-2018 CVS48_RS09395 5496acc14bba61dae548ade6fffe52a6 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 17 39 4.4E-7 T 29-03-2018 CVS48_RS28990 e76edeeef247e11ee5e1cfcb6403d336 263 SUPERFAMILY SSF52799 22 256 7.78E-46 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like CVS48_RS28990 e76edeeef247e11ee5e1cfcb6403d336 263 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 157 167 - T 29-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 CVS48_RS28990 e76edeeef247e11ee5e1cfcb6403d336 263 Gene3D G3DSA:3.90.190.10 41 207 7.7E-20 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like CVS48_RS28990 e76edeeef247e11ee5e1cfcb6403d336 263 Pfam PF13350 Tyrosine phosphatase family 22 261 7.4E-58 T 29-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type CVS48_RS16100 1322c6ebe54a3d3de63b1fa5f829b80c 838 Gene3D G3DSA:2.40.170.20 278 838 5.5E-76 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS16100 1322c6ebe54a3d3de63b1fa5f829b80c 838 SUPERFAMILY SSF56935 129 837 1.39E-112 T 29-03-2018 CVS48_RS16100 1322c6ebe54a3d3de63b1fa5f829b80c 838 Pfam PF07715 TonB-dependent Receptor Plug Domain 170 270 4.3E-13 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS16100 1322c6ebe54a3d3de63b1fa5f829b80c 838 Gene3D G3DSA:2.170.130.10 127 277 1.2E-18 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS16100 1322c6ebe54a3d3de63b1fa5f829b80c 838 Pfam PF07660 Secretin and TonB N terminus short domain 76 123 2.9E-11 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS16100 1322c6ebe54a3d3de63b1fa5f829b80c 838 Pfam PF00593 TonB dependent receptor 365 835 1.2E-43 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS16100 1322c6ebe54a3d3de63b1fa5f829b80c 838 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 171 835 9.9E-102 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS16100 1322c6ebe54a3d3de63b1fa5f829b80c 838 SMART SM00965 74 124 2.8E-15 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS19705 5b79259e19b2cf433ffbe4438d307a92 548 SUPERFAMILY SSF161098 6 267 1.96E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19705 5b79259e19b2cf433ffbe4438d307a92 548 SUPERFAMILY SSF161098 289 541 2.06E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19705 5b79259e19b2cf433ffbe4438d307a92 548 Gene3D G3DSA:1.10.3720.10 8 274 3.8E-37 T 29-03-2018 CVS48_RS19705 5b79259e19b2cf433ffbe4438d307a92 548 Gene3D G3DSA:1.10.3720.10 289 544 1.9E-25 T 29-03-2018 CVS48_RS19705 5b79259e19b2cf433ffbe4438d307a92 548 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 360 539 7.5E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19705 5b79259e19b2cf433ffbe4438d307a92 548 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 272 2.2E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10765 9f0461178c08074a0ff27492f9beedc1 325 Gene3D G3DSA:3.40.190.10 142 233 4.6E-5 T 29-03-2018 CVS48_RS10765 9f0461178c08074a0ff27492f9beedc1 325 PIRSF PIRSF006470 1 325 1.8E-95 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS10765 9f0461178c08074a0ff27492f9beedc1 325 SUPERFAMILY SSF53850 137 273 2.53E-5 T 29-03-2018 CVS48_RS10765 9f0461178c08074a0ff27492f9beedc1 325 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 32 308 6.9E-90 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS10765 9f0461178c08074a0ff27492f9beedc1 325 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 35 284 1.5E-72 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS18185 1674e9a706776f685ce7ab7d0c995b91 217 SUPERFAMILY SSF52499 13 208 1.7E-41 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS18185 1674e9a706776f685ce7ab7d0c995b91 217 Pfam PF00857 Isochorismatase family 20 170 4.0E-25 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS18185 1674e9a706776f685ce7ab7d0c995b91 217 Gene3D G3DSA:3.40.50.850 5 206 7.5E-31 T 29-03-2018 CVS48_RS24725 5ed7c0b29b2a7acc224f309c7b9430df 210 Gene3D G3DSA:2.30.110.10 1 207 3.3E-68 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS24725 5ed7c0b29b2a7acc224f309c7b9430df 210 PIRSF PIRSF010372 1 207 1.6E-64 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type CVS48_RS24725 5ed7c0b29b2a7acc224f309c7b9430df 210 SUPERFAMILY SSF50475 11 192 1.31E-38 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS24725 5ed7c0b29b2a7acc224f309c7b9430df 210 Pfam PF04299 Putative FMN-binding domain 1 167 4.3E-60 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type CVS48_RS04460 8ef9e50c09b6ffa20bf99779c75f8d60 509 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 505 1.9E-219 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04460 8ef9e50c09b6ffa20bf99779c75f8d60 509 Gene3D G3DSA:1.10.275.10 1 196 2.3E-73 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CVS48_RS04460 8ef9e50c09b6ffa20bf99779c75f8d60 509 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 2 503 44.621 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CVS48_RS04460 8ef9e50c09b6ffa20bf99779c75f8d60 509 SUPERFAMILY SSF48557 3 504 1.96E-190 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CVS48_RS04460 8ef9e50c09b6ffa20bf99779c75f8d60 509 Pfam PF00221 Aromatic amino acid lyase 10 470 1.6E-185 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CVS48_RS04460 8ef9e50c09b6ffa20bf99779c75f8d60 509 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 138 153 - T 29-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CVS48_RS04460 8ef9e50c09b6ffa20bf99779c75f8d60 509 Gene3D G3DSA:1.20.200.10 198 504 1.4E-119 T 29-03-2018 CVS48_RS13040 301fe3ba0d6dff2e80d079a2dc6fa634 433 Gene3D G3DSA:3.40.190.10 173 388 2.1E-40 T 29-03-2018 CVS48_RS13040 301fe3ba0d6dff2e80d079a2dc6fa634 433 Gene3D G3DSA:3.40.190.10 59 160 2.2E-8 T 29-03-2018 CVS48_RS13040 301fe3ba0d6dff2e80d079a2dc6fa634 433 Pfam PF13379 NMT1-like family 58 308 1.9E-104 T 29-03-2018 CVS48_RS13040 301fe3ba0d6dff2e80d079a2dc6fa634 433 SUPERFAMILY SSF53850 61 299 5.7E-30 T 29-03-2018 CVS48_RS23285 3e33bd4a46322d22f27978d7f10ed062 397 Pfam PF12536 Patatin phospholipase 277 381 1.1E-34 T 29-03-2018 IPR021095 Protein of unknown function DUF3734 CVS48_RS23285 3e33bd4a46322d22f27978d7f10ed062 397 Gene3D G3DSA:3.40.1090.10 6 323 3.5E-39 T 29-03-2018 CVS48_RS23285 3e33bd4a46322d22f27978d7f10ed062 397 SUPERFAMILY SSF52151 147 370 4.01E-52 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CVS48_RS23285 3e33bd4a46322d22f27978d7f10ed062 397 SUPERFAMILY SSF52151 20 92 4.01E-52 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CVS48_RS23285 3e33bd4a46322d22f27978d7f10ed062 397 Pfam PF01734 Patatin-like phospholipase 151 240 4.0E-9 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CVS48_RS23285 3e33bd4a46322d22f27978d7f10ed062 397 Pfam PF01734 Patatin-like phospholipase 23 82 2.8E-12 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CVS48_RS11765 ac7599faacc9954f4709b5bc42531492 305 Gene3D G3DSA:3.60.15.10 12 304 1.4E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS11765 ac7599faacc9954f4709b5bc42531492 305 Pfam PF00753 Metallo-beta-lactamase superfamily 74 258 5.7E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS11765 ac7599faacc9954f4709b5bc42531492 305 SUPERFAMILY SSF56281 18 302 1.7E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS11765 ac7599faacc9954f4709b5bc42531492 305 SMART SM00849 73 280 2.8E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS22305 67e5831ffa7cb5e2a22f95ee9f9fe0a1 256 SMART SM00382 29 226 2.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22305 67e5831ffa7cb5e2a22f95ee9f9fe0a1 256 SUPERFAMILY SSF52540 5 248 1.33E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22305 67e5831ffa7cb5e2a22f95ee9f9fe0a1 256 PIRSF PIRSF039085 1 254 9.0E-103 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS22305 67e5831ffa7cb5e2a22f95ee9f9fe0a1 256 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 6 254 7.0E-105 T 29-03-2018 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein CVS48_RS22305 67e5831ffa7cb5e2a22f95ee9f9fe0a1 256 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS22305 67e5831ffa7cb5e2a22f95ee9f9fe0a1 256 Pfam PF00005 ABC transporter 20 177 6.6E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22305 67e5831ffa7cb5e2a22f95ee9f9fe0a1 256 Gene3D G3DSA:3.40.50.300 1 254 7.7E-71 T 29-03-2018 CVS48_RS16560 e81f05f87bc3e27d3f72da07fd48538a 286 Gene3D G3DSA:3.20.20.60 2 286 2.6E-82 T 29-03-2018 CVS48_RS16560 e81f05f87bc3e27d3f72da07fd48538a 286 SUPERFAMILY SSF51621 12 284 7.18E-90 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS16560 e81f05f87bc3e27d3f72da07fd48538a 286 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 243 6.3E-50 T 29-03-2018 CVS48_RS16560 e81f05f87bc3e27d3f72da07fd48538a 286 ProSitePatterns PS00161 Isocitrate lyase signature. 114 119 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CVS48_RS13095 96803896836ebac8ee191462cbc6f169 386 Gene3D G3DSA:3.90.1150.10 291 386 6.1E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS13095 96803896836ebac8ee191462cbc6f169 386 Pfam PF00155 Aminotransferase class I and II 32 380 7.3E-59 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS13095 96803896836ebac8ee191462cbc6f169 386 SUPERFAMILY SSF53383 1 385 3.09E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS13095 96803896836ebac8ee191462cbc6f169 386 Gene3D G3DSA:3.40.640.10 46 290 5.5E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS24965 aca01479bc35c9235c1d36cc15fca51e 890 Gene3D G3DSA:2.160.20.10 46 347 1.8E-55 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS24965 aca01479bc35c9235c1d36cc15fca51e 890 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 24 1.1E-8 T 29-03-2018 IPR024973 ESPR domain CVS48_RS24965 aca01479bc35c9235c1d36cc15fca51e 890 Pfam PF05860 haemagglutination activity domain 71 162 4.1E-23 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS24965 aca01479bc35c9235c1d36cc15fca51e 890 SMART SM00912 51 165 1.6E-29 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS24965 aca01479bc35c9235c1d36cc15fca51e 890 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 87 160 4.8E-23 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS24965 aca01479bc35c9235c1d36cc15fca51e 890 SUPERFAMILY SSF51126 49 340 1.95E-42 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS27395 787c43011ecd21df6d5df1a5dd8fe7bf 282 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 11 275 5.7E-127 T 29-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 CVS48_RS27395 787c43011ecd21df6d5df1a5dd8fe7bf 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 276 8.9E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27395 787c43011ecd21df6d5df1a5dd8fe7bf 282 Gene3D G3DSA:1.10.3720.10 15 278 8.1E-50 T 29-03-2018 CVS48_RS27395 787c43011ecd21df6d5df1a5dd8fe7bf 282 SUPERFAMILY SSF161098 19 269 1.04E-55 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27395 787c43011ecd21df6d5df1a5dd8fe7bf 282 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 15 270 1.2E-96 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CVS48_RS02960 f14d7e01b37933259fd74dcb9fc157e1 320 SUPERFAMILY SSF46689 268 316 4.93E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS02960 f14d7e01b37933259fd74dcb9fc157e1 320 SUPERFAMILY SSF52317 1 197 5.04E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS02960 f14d7e01b37933259fd74dcb9fc157e1 320 Pfam PF12833 Helix-turn-helix domain 238 314 1.3E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS02960 f14d7e01b37933259fd74dcb9fc157e1 320 SUPERFAMILY SSF46689 216 266 2.11E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS02960 f14d7e01b37933259fd74dcb9fc157e1 320 Gene3D G3DSA:3.40.50.880 2 213 4.6E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS02960 f14d7e01b37933259fd74dcb9fc157e1 320 SMART SM00342 232 315 6.4E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CVS48_RS02960 f14d7e01b37933259fd74dcb9fc157e1 320 Pfam PF01965 DJ-1/PfpI family 5 176 2.6E-9 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS02960 f14d7e01b37933259fd74dcb9fc157e1 320 Gene3D G3DSA:1.10.10.60 266 315 1.6E-6 T 29-03-2018 CVS48_RS02960 f14d7e01b37933259fd74dcb9fc157e1 320 Gene3D G3DSA:1.10.10.60 214 265 2.3E-12 T 29-03-2018 CVS48_RS09280 9841e4ca5413b8d0c07b494f8acfe93f 162 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 144 2.4E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS09280 9841e4ca5413b8d0c07b494f8acfe93f 162 Gene3D G3DSA:3.10.180.10 10 156 5.3E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS09280 9841e4ca5413b8d0c07b494f8acfe93f 162 SUPERFAMILY SSF54593 12 150 3.62E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 SMART SM00895 99 225 6.0E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 4.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 4.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 Gene3D G3DSA:1.10.10.10 6 77 1.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 SUPERFAMILY SSF48008 95 233 7.85E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 4.3E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 SUPERFAMILY SSF46785 6 79 2.92E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 SMART SM00345 16 75 1.0E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 Gene3D G3DSA:1.20.120.530 92 235 1.2E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS08825 4c8cebba334d130d83cb47ddd10f87e4 235 Pfam PF07729 FCD domain 100 223 2.0E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 202 1.6E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 Pfam PF00072 Response regulator receiver domain 15 123 2.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 SMART SM00421 147 204 5.4E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 SUPERFAMILY SSF46894 139 205 8.16E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 SUPERFAMILY SSF52172 13 159 8.68E-32 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 Gene3D G3DSA:3.40.50.2300 1 141 3.7E-28 T 29-03-2018 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 SMART SM00448 13 123 6.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS17945 91c976d9a221a77adc227dde107efe26 209 Gene3D G3DSA:1.10.10.10 142 207 2.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS07575 ddeca84b0c87ae539a9e269b09d95d5a 141 Pfam PF02566 OsmC-like protein 44 138 1.2E-14 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS07575 ddeca84b0c87ae539a9e269b09d95d5a 141 SUPERFAMILY SSF82784 1 140 9.29E-44 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS07575 ddeca84b0c87ae539a9e269b09d95d5a 141 Gene3D G3DSA:2.20.25.10 4 47 5.0E-19 T 29-03-2018 CVS48_RS07575 ddeca84b0c87ae539a9e269b09d95d5a 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 3.4E-54 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CVS48_RS07575 ddeca84b0c87ae539a9e269b09d95d5a 141 Gene3D G3DSA:3.30.300.20 48 141 5.8E-22 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS26785 e5e57e6d0359efaac51db09489e19c8b 543 SUPERFAMILY SSF48452 268 392 9.59E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS26785 e5e57e6d0359efaac51db09489e19c8b 543 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 3 390 3.4E-86 T 29-03-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 CVS48_RS26785 e5e57e6d0359efaac51db09489e19c8b 543 Pfam PF07219 HemY protein N-terminus 26 133 1.7E-26 T 29-03-2018 IPR010817 HemY, N-terminal CVS48_RS26785 e5e57e6d0359efaac51db09489e19c8b 543 Gene3D G3DSA:1.25.40.10 59 233 2.3E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS26785 e5e57e6d0359efaac51db09489e19c8b 543 Gene3D G3DSA:1.25.40.10 267 395 2.7E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS01555 d267a2dce31b9aa28383acd85563138d 168 SMART SM00347 43 143 3.2E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS01555 d267a2dce31b9aa28383acd85563138d 168 Gene3D G3DSA:1.10.10.10 22 160 6.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01555 d267a2dce31b9aa28383acd85563138d 168 SUPERFAMILY SSF46785 23 154 3.52E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01555 d267a2dce31b9aa28383acd85563138d 168 Pfam PF12802 MarR family 49 107 6.1E-10 T 29-03-2018 CVS48_RS01555 d267a2dce31b9aa28383acd85563138d 168 ProSitePatterns PS01117 MarR-type HTH domain signature. 82 116 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 PIRSF PIRSF000410 3 282 1.3E-95 T 29-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 Pfam PF03705 CheR methyltransferase, all-alpha domain 22 74 4.0E-16 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 Gene3D G3DSA:3.40.50.150 88 281 2.5E-47 T 29-03-2018 CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 SUPERFAMILY SSF47757 12 88 3.53E-22 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 PRINTS PR00996 Glutamate methyltransferase family signature 149 165 1.4E-46 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 PRINTS PR00996 Glutamate methyltransferase family signature 82 94 1.4E-46 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 PRINTS PR00996 Glutamate methyltransferase family signature 221 235 1.4E-46 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 PRINTS PR00996 Glutamate methyltransferase family signature 240 263 1.4E-46 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 PRINTS PR00996 Glutamate methyltransferase family signature 43 56 1.4E-46 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 PRINTS PR00996 Glutamate methyltransferase family signature 115 135 1.4E-46 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 SMART SM00138 21 281 8.1E-104 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 Pfam PF01739 CheR methyltransferase, SAM binding domain 89 276 4.5E-57 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 Gene3D G3DSA:1.10.155.10 13 87 4.4E-22 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CVS48_RS16805 b4fd0965c416437c2281f645d42fa1e5 284 SUPERFAMILY SSF53335 89 278 2.21E-58 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS08395 eed43cc7382df633d967b1396413acc9 332 Pfam PF03524 Conjugal transfer protein 32 110 3.1E-11 T 29-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX CVS48_RS08395 eed43cc7382df633d967b1396413acc9 332 Pfam PF10671 Toxin co-regulated pilus biosynthesis protein Q 251 330 5.8E-18 T 29-03-2018 IPR018927 Toxin co-regulated pilus biosynthesis protein Q, C-terminal CVS48_RS28350 1ab3abc858a5aba012f6db6775cb4d9a 236 PIRSF PIRSF005917 1 231 3.1E-45 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS28350 1ab3abc858a5aba012f6db6775cb4d9a 236 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 214 6.7E-9 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS28350 1ab3abc858a5aba012f6db6775cb4d9a 236 SUPERFAMILY SSF53790 3 232 1.57E-63 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS28350 1ab3abc858a5aba012f6db6775cb4d9a 236 Gene3D G3DSA:3.30.950.10 121 230 6.7E-24 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS28350 1ab3abc858a5aba012f6db6775cb4d9a 236 Gene3D G3DSA:3.40.1010.10 2 120 1.1E-28 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CVS48_RS12090 d84c0d46ae423d743addcf136b9642d6 261 Pfam PF02104 SURF1 family 31 241 7.7E-41 T 29-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS15965 6a5495ff178cf3736be300285dc60567 227 Pfam PF01914 MarC family integral membrane protein 15 220 1.4E-50 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CVS48_RS15965 6a5495ff178cf3736be300285dc60567 227 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 21 217 5.4E-33 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CVS48_RS22695 d573594baa8da99b782e7461691eb523 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 7.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS22695 d573594baa8da99b782e7461691eb523 215 Gene3D G3DSA:1.10.10.60 5 58 5.6E-12 T 29-03-2018 CVS48_RS22695 d573594baa8da99b782e7461691eb523 215 Gene3D G3DSA:1.10.10.60 59 210 2.2E-8 T 29-03-2018 CVS48_RS22695 d573594baa8da99b782e7461691eb523 215 SUPERFAMILY SSF46689 18 91 3.29E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS22980 a7d052301c9e8695d20f5838af024519 347 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS22980 a7d052301c9e8695d20f5838af024519 347 SMART SM00382 56 247 7.6E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22980 a7d052301c9e8695d20f5838af024519 347 Pfam PF00005 ABC transporter 48 197 5.7E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22980 a7d052301c9e8695d20f5838af024519 347 SUPERFAMILY SSF52540 19 269 2.6E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22980 a7d052301c9e8695d20f5838af024519 347 Gene3D G3DSA:3.40.50.300 15 342 4.4E-79 T 29-03-2018 CVS48_RS22980 a7d052301c9e8695d20f5838af024519 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 247 332 1.6E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS22980 a7d052301c9e8695d20f5838af024519 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 314 1.6E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS22865 9cc27280b90f4355f18bba9b8fd9cd83 519 SUPERFAMILY SSF53955 115 435 9.9E-67 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS22865 9cc27280b90f4355f18bba9b8fd9cd83 519 Gene3D G3DSA:1.10.101.10 436 515 1.2E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like CVS48_RS22865 9cc27280b90f4355f18bba9b8fd9cd83 519 Gene3D G3DSA:1.10.8.350 190 293 5.2E-22 T 29-03-2018 CVS48_RS22865 9cc27280b90f4355f18bba9b8fd9cd83 519 Pfam PF13406 Transglycosylase SLT domain 127 427 2.2E-75 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 CVS48_RS22865 9cc27280b90f4355f18bba9b8fd9cd83 519 SUPERFAMILY SSF47090 436 505 1.23E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like CVS48_RS22865 9cc27280b90f4355f18bba9b8fd9cd83 519 Gene3D G3DSA:1.10.530.10 299 435 2.4E-25 T 29-03-2018 CVS48_RS22865 9cc27280b90f4355f18bba9b8fd9cd83 519 Pfam PF01471 Putative peptidoglycan binding domain 450 505 5.2E-13 T 29-03-2018 IPR002477 Peptidoglycan binding-like CVS48_RS10085 51aaee421d213582d30b38e5cd5cff6e 265 SUPERFAMILY SSF54427 142 249 2.67E-17 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS10085 51aaee421d213582d30b38e5cd5cff6e 265 Pfam PF12680 SnoaL-like domain 151 244 5.3E-8 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CVS48_RS10085 51aaee421d213582d30b38e5cd5cff6e 265 Pfam PF12680 SnoaL-like domain 20 111 1.3E-8 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CVS48_RS10085 51aaee421d213582d30b38e5cd5cff6e 265 Gene3D G3DSA:3.10.450.50 137 263 1.4E-16 T 29-03-2018 CVS48_RS10085 51aaee421d213582d30b38e5cd5cff6e 265 Gene3D G3DSA:3.10.450.50 10 127 2.8E-14 T 29-03-2018 CVS48_RS10085 51aaee421d213582d30b38e5cd5cff6e 265 SUPERFAMILY SSF54427 18 113 3.58E-17 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS25720 fcdd9db0cf526659a17f1794ec8026bb 288 Gene3D G3DSA:3.40.50.10320 35 285 4.4E-22 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CVS48_RS25720 fcdd9db0cf526659a17f1794ec8026bb 288 Pfam PF02585 GlcNAc-PI de-N-acetylase 71 199 1.6E-7 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CVS48_RS25720 fcdd9db0cf526659a17f1794ec8026bb 288 SUPERFAMILY SSF102588 68 278 4.45E-23 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CVS48_RS28705 61619dd8dfe7689f7b1b4ef7d93ee7f5 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 118 1.9E-39 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28705 61619dd8dfe7689f7b1b4ef7d93ee7f5 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 119 20.287 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 SUPERFAMILY SSF53822 27 367 2.59E-89 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 Gene3D G3DSA:3.40.50.2300 26 216 1.9E-40 T 29-03-2018 CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 1.1E-32 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 1.1E-32 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 332 347 1.1E-32 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 281 294 1.1E-32 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 1.1E-32 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 1.1E-32 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 1.1E-32 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 Pfam PF13458 Periplasmic binding protein 28 367 1.8E-56 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS19290 fad879a4871f93ebdf6cb4d1bb3b58cc 371 Gene3D G3DSA:3.40.50.2300 217 355 2.2E-16 T 29-03-2018 CVS48_RS17055 4fa0827d03816a0c8ed8f6120af1c5b3 410 Gene3D G3DSA:3.40.50.10540 9 410 4.2E-131 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS17055 4fa0827d03816a0c8ed8f6120af1c5b3 410 SUPERFAMILY SSF89796 11 404 8.37E-126 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS17055 4fa0827d03816a0c8ed8f6120af1c5b3 410 Pfam PF02515 CoA-transferase family III 15 381 3.3E-108 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS22785 dd0f6753ced2702058e4e93ed3b8fe35 245 SUPERFAMILY SSF53850 17 233 3.84E-31 T 29-03-2018 CVS48_RS22785 dd0f6753ced2702058e4e93ed3b8fe35 245 SMART SM00062 16 239 1.8E-20 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS22785 dd0f6753ced2702058e4e93ed3b8fe35 245 Gene3D G3DSA:3.40.190.10 119 195 1.4E-6 T 29-03-2018 CVS48_RS22785 dd0f6753ced2702058e4e93ed3b8fe35 245 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 30 230 1.4E-19 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS22785 dd0f6753ced2702058e4e93ed3b8fe35 245 Gene3D G3DSA:3.40.190.10 7 118 1.8E-13 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 6 244 1.2E-56 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 545 784 6.0E-64 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Gene3D G3DSA:1.20.120.330 791 925 7.8E-34 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 SUPERFAMILY SSF81593 794 922 9.42E-31 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 SUPERFAMILY SSF81301 519 794 2.53E-74 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 SUPERFAMILY SSF81593 272 427 4.0E-37 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Gene3D G3DSA:1.10.4050.10 3 88 3.9E-4 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Gene3D G3DSA:1.10.4050.10 519 633 6.1E-19 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 SUPERFAMILY SSF81301 6 271 1.57E-63 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Pfam PF08335 GlnD PII-uridylyltransferase 282 427 3.3E-40 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Pfam PF08335 GlnD PII-uridylyltransferase 806 896 4.8E-9 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Gene3D G3DSA:3.30.460.10 90 269 2.7E-54 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Gene3D G3DSA:3.30.460.10 634 790 1.2E-51 T 29-03-2018 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 2 924 18.551 T 29-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 CVS48_RS14450 ff23046e502246cca9c2de4ea9768ecb 930 Gene3D G3DSA:1.20.120.330 270 430 1.5E-43 T 29-03-2018 CVS48_RS18955 17faf793c0cfe76274d0c80b5dc7d562 524 Pfam PF00571 CBS domain 374 423 2.7E-6 T 29-03-2018 IPR000644 CBS domain CVS48_RS18955 17faf793c0cfe76274d0c80b5dc7d562 524 Gene3D G3DSA:3.30.465.10 434 520 1.2E-15 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS18955 17faf793c0cfe76274d0c80b5dc7d562 524 SUPERFAMILY SSF54631 294 426 3.42E-22 T 29-03-2018 CVS48_RS18955 17faf793c0cfe76274d0c80b5dc7d562 524 SMART SM01091 438 518 1.6E-18 T 29-03-2018 IPR005170 Transporter-associated domain CVS48_RS18955 17faf793c0cfe76274d0c80b5dc7d562 524 Gene3D G3DSA:3.10.580.10 287 433 6.3E-23 T 29-03-2018 CVS48_RS18955 17faf793c0cfe76274d0c80b5dc7d562 524 Pfam PF03741 Integral membrane protein TerC family 17 206 1.0E-49 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CVS48_RS18955 17faf793c0cfe76274d0c80b5dc7d562 524 Pfam PF03471 Transporter associated domain 439 516 2.0E-14 T 29-03-2018 IPR005170 Transporter-associated domain CVS48_RS18955 17faf793c0cfe76274d0c80b5dc7d562 524 SUPERFAMILY SSF56176 433 515 4.36E-15 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS25465 d8b7eb4395b440dc0b8f519980e68737 638 Gene3D G3DSA:2.60.120.200 122 361 1.4E-30 T 29-03-2018 CVS48_RS25465 d8b7eb4395b440dc0b8f519980e68737 638 SUPERFAMILY SSF49899 135 288 4.45E-28 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CVS48_RS25465 d8b7eb4395b440dc0b8f519980e68737 638 SUPERFAMILY SSF49899 327 358 4.45E-28 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CVS48_RS25465 d8b7eb4395b440dc0b8f519980e68737 638 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 195 300 1.5E-14 T 29-03-2018 CVS48_RS25465 d8b7eb4395b440dc0b8f519980e68737 638 Pfam PF10102 Domain of unknown function (DUF2341) 72 153 2.3E-19 T 29-03-2018 IPR018765 Domain of unknown function DUF2341 CVS48_RS25465 d8b7eb4395b440dc0b8f519980e68737 638 Pfam PF01618 MotA/TolQ/ExbB proton channel family 479 589 8.1E-26 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CVS48_RS25465 d8b7eb4395b440dc0b8f519980e68737 638 SMART SM00560 202 352 0.0016 T 29-03-2018 IPR006558 LamG-like jellyroll fold CVS48_RS19100 abab81a2d44404e1096e1d6dae2c31bf 104 SUPERFAMILY SSF63592 5 82 2.35E-13 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CVS48_RS19100 abab81a2d44404e1096e1d6dae2c31bf 104 Gene3D G3DSA:1.10.4000.10 4 97 7.1E-18 T 29-03-2018 CVS48_RS19100 abab81a2d44404e1096e1d6dae2c31bf 104 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 11 81 3.0E-6 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CVS48_RS19100 abab81a2d44404e1096e1d6dae2c31bf 104 Pfam PF05247 Flagellar transcriptional activator (FlhD) 5 84 9.8E-13 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CVS48_RS05705 c6e963583fd522ae3dd1b37ae81e5531 674 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 29 662 2.1E-211 T 29-03-2018 IPR011853 TRAP transporter, 4TM/12TM fusion protein CVS48_RS05705 c6e963583fd522ae3dd1b37ae81e5531 674 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 139 588 2.4E-116 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS11055 46560f6fd10112c5908ee4c8424aea0a 272 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 270 33.708 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS11055 46560f6fd10112c5908ee4c8424aea0a 272 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS11055 46560f6fd10112c5908ee4c8424aea0a 272 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 252 2.8E-69 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS11055 46560f6fd10112c5908ee4c8424aea0a 272 SMART SM00934 17 257 3.1E-52 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS11055 46560f6fd10112c5908ee4c8424aea0a 272 SUPERFAMILY SSF51366 2 257 1.63E-73 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CVS48_RS11055 46560f6fd10112c5908ee4c8424aea0a 272 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 248 1.5E-29 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CVS48_RS11055 46560f6fd10112c5908ee4c8424aea0a 272 Gene3D G3DSA:3.20.20.70 1 272 8.5E-79 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS04940 499b51cfc49949bf4c22a7d49ca5c71d 191 Gene3D G3DSA:3.40.30.10 35 186 2.2E-7 T 29-03-2018 CVS48_RS04940 499b51cfc49949bf4c22a7d49ca5c71d 191 SUPERFAMILY SSF52833 45 185 8.47E-12 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS28100 19a8ad491aec74710b3e09672ae8bb75 114 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 8.4E-12 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CVS48_RS28100 19a8ad491aec74710b3e09672ae8bb75 114 Gene3D G3DSA:3.30.70.100 1 94 6.0E-17 T 29-03-2018 CVS48_RS28100 19a8ad491aec74710b3e09672ae8bb75 114 SUPERFAMILY SSF54909 1 100 3.71E-25 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS06270 40bd93f15c73073c144351684a74f2eb 126 Gene3D G3DSA:1.20.5.710 3 55 4.2E-16 T 29-03-2018 CVS48_RS06270 40bd93f15c73073c144351684a74f2eb 126 SUPERFAMILY SSF48300 4 62 1.27E-15 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06270 40bd93f15c73073c144351684a74f2eb 126 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 62 97 2.0E-12 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06270 40bd93f15c73073c144351684a74f2eb 126 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 126 1.1E-47 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06270 40bd93f15c73073c144351684a74f2eb 126 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 52 3.3E-18 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06270 40bd93f15c73073c144351684a74f2eb 126 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 126 4.3E-30 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06270 40bd93f15c73073c144351684a74f2eb 126 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 126 25.401 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06270 40bd93f15c73073c144351684a74f2eb 126 SUPERFAMILY SSF54736 55 126 4.36E-24 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CVS48_RS06270 40bd93f15c73073c144351684a74f2eb 126 Gene3D G3DSA:3.30.1390.10 56 126 1.9E-30 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CVS48_RS01910 89773210c146c17798853aff1ba120ce 331 PIRSF PIRSF017082 3 330 2.8E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01910 89773210c146c17798853aff1ba120ce 331 SUPERFAMILY SSF53850 118 289 1.09E-15 T 29-03-2018 CVS48_RS01910 89773210c146c17798853aff1ba120ce 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 327 7.2E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS01910 89773210c146c17798853aff1ba120ce 331 Gene3D G3DSA:3.40.190.10 131 241 6.9E-13 T 29-03-2018 CVS48_RS20580 c47faf724bd8c36b8ccdc7cd3f86d1c7 174 SUPERFAMILY SSF49329 32 173 2.23E-43 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CVS48_RS20580 c47faf724bd8c36b8ccdc7cd3f86d1c7 174 Gene3D G3DSA:2.60.40.200 21 174 4.1E-34 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CVS48_RS20580 c47faf724bd8c36b8ccdc7cd3f86d1c7 174 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 36 173 1.2E-30 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 SUPERFAMILY SSF81901 31 212 2.09E-41 T 29-03-2018 CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 SMART SM00671 42 77 6.7E-6 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 SMART SM00671 78 113 2.9E-6 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 SMART SM00671 151 186 0.018 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 SMART SM00671 116 150 0.073 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 Gene3D G3DSA:2.60.40.1180 77 142 4.5E-15 T 29-03-2018 CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 Gene3D G3DSA:2.60.40.1180 29 76 6.2E-7 T 29-03-2018 CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 Gene3D G3DSA:2.60.40.1180 143 205 1.1E-11 T 29-03-2018 CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 Pfam PF08238 Sel1 repeat 158 186 0.014 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 Pfam PF08238 Sel1 repeat 43 77 8.0E-5 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 Pfam PF08238 Sel1 repeat 189 210 130.0 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 Pfam PF08238 Sel1 repeat 79 112 6.7E-6 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS07215 fbc93b5230000088d2a96d16bed1fcdb 240 Pfam PF08238 Sel1 repeat 117 150 4.9E-4 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS05195 b9d0b478b009f0aa95e6f2ef44947aef 203 SUPERFAMILY SSF52833 1 101 7.6E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS05195 b9d0b478b009f0aa95e6f2ef44947aef 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 1.5E-16 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS05195 b9d0b478b009f0aa95e6f2ef44947aef 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 111 188 9.5E-9 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS05195 b9d0b478b009f0aa95e6f2ef44947aef 203 Gene3D G3DSA:3.40.30.10 1 88 1.1E-26 T 29-03-2018 CVS48_RS05195 b9d0b478b009f0aa95e6f2ef44947aef 203 Gene3D G3DSA:1.20.1050.10 89 203 5.2E-22 T 29-03-2018 CVS48_RS05195 b9d0b478b009f0aa95e6f2ef44947aef 203 SUPERFAMILY SSF47616 80 200 1.81E-23 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS10955 ae7efa0011aa3b81a97e176c3ccdeea3 404 Pfam PF03594 Benzoate membrane transport protein 21 395 3.6E-131 T 29-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 CVS48_RS10955 ae7efa0011aa3b81a97e176c3ccdeea3 404 TIGRFAM TIGR00843 benE: benzoate transporter 23 395 4.9E-108 T 29-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Gene3D G3DSA:1.10.1060.10 797 952 8.6E-13 T 29-03-2018 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Gene3D G3DSA:3.30.465.10 261 447 3.6E-20 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 SUPERFAMILY SSF56176 156 425 1.45E-53 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 916 927 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Pfam PF02754 Cysteine-rich domain 1186 1272 1.2E-4 T 29-03-2018 IPR004017 Cysteine-rich domain CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Pfam PF02754 Cysteine-rich domain 1061 1150 4.8E-7 T 29-03-2018 IPR004017 Cysteine-rich domain CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Pfam PF13183 4Fe-4S dicluster domain 852 930 8.4E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Pfam PF11880 Domain of unknown function (DUF3400) 1275 1319 5.7E-24 T 29-03-2018 IPR021817 Protein of unknown function DUF3400 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 SUPERFAMILY SSF55103 430 559 8.78E-40 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 SUPERFAMILY SSF55103 693 818 8.78E-40 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Pfam PF02913 FAD linked oxidases, C-terminal domain 459 576 0.0027 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Pfam PF02913 FAD linked oxidases, C-terminal domain 718 815 1.0E-17 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Gene3D G3DSA:3.30.43.10 143 246 2.3E-14 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Pfam PF12447 Protein of unknown function (DUF3683) 21 144 2.2E-50 T 29-03-2018 IPR022153 Protein of unknown function DUF3683 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 SUPERFAMILY SSF46548 825 946 6.28E-13 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CVS48_RS07845 2abf75ad95c6c29b7ba9a7f84028f051 1319 Pfam PF01565 FAD binding domain 194 339 2.2E-26 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS01510 1d888eb4ea3ea5b2379176efc28c14c2 69 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 44 2.6E-11 T 29-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB CVS48_RS13465 bd066574d8020e85ae36a25080565059 302 PIRSF PIRSF036979 8 292 8.7E-66 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS13465 bd066574d8020e85ae36a25080565059 302 Gene3D G3DSA:3.40.800.10 1 296 1.2E-69 T 29-03-2018 CVS48_RS13465 bd066574d8020e85ae36a25080565059 302 Pfam PF00491 Arginase family 15 285 3.7E-67 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS13465 bd066574d8020e85ae36a25080565059 302 SUPERFAMILY SSF52768 14 287 1.04E-70 T 29-03-2018 CVS48_RS23120 f486c0d2fc8e431e0ab8789c98c90dd1 325 Gene3D G3DSA:3.40.190.10 31 159 0.035 T 29-03-2018 CVS48_RS23120 f486c0d2fc8e431e0ab8789c98c90dd1 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 6.4E-79 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23120 f486c0d2fc8e431e0ab8789c98c90dd1 325 PIRSF PIRSF017082 1 325 4.8E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23120 f486c0d2fc8e431e0ab8789c98c90dd1 325 SUPERFAMILY SSF53850 114 280 1.09E-9 T 29-03-2018 CVS48_RS23120 f486c0d2fc8e431e0ab8789c98c90dd1 325 Gene3D G3DSA:3.40.190.10 160 296 3.6E-8 T 29-03-2018 CVS48_RS20465 4098df8d423237c928f2775ba275c8ab 394 Gene3D G3DSA:1.20.1250.20 210 393 2.4E-17 T 29-03-2018 CVS48_RS20465 4098df8d423237c928f2775ba275c8ab 394 SUPERFAMILY SSF103473 6 390 4.19E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS20465 4098df8d423237c928f2775ba275c8ab 394 Pfam PF07690 Major Facilitator Superfamily 17 333 5.8E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS20465 4098df8d423237c928f2775ba275c8ab 394 Gene3D G3DSA:1.20.1250.20 5 191 6.8E-22 T 29-03-2018 CVS48_RS24290 f540b7fc16bcd8171a385d4fd15cfa48 85 Gene3D G3DSA:1.10.10.620 2 62 3.2E-11 T 29-03-2018 CVS48_RS08835 2a09f275433e7600777717fa1827aeef 456 Pfam PF07690 Major Facilitator Superfamily 33 397 1.6E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS08835 2a09f275433e7600777717fa1827aeef 456 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS08835 2a09f275433e7600777717fa1827aeef 456 ProSitePatterns PS00216 Sugar transport proteins signature 1. 318 334 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS08835 2a09f275433e7600777717fa1827aeef 456 SUPERFAMILY SSF103473 21 447 3.92E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS08835 2a09f275433e7600777717fa1827aeef 456 Gene3D G3DSA:1.20.1250.20 247 448 3.0E-20 T 29-03-2018 CVS48_RS08835 2a09f275433e7600777717fa1827aeef 456 Gene3D G3DSA:1.20.1250.20 15 232 4.8E-24 T 29-03-2018 CVS48_RS11930 f05a4430ed6e57df7a63d85e879496fd 222 SUPERFAMILY SSF89562 24 184 5.23E-47 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS11930 f05a4430ed6e57df7a63d85e879496fd 222 Pfam PF03737 Aldolase/RraA 27 173 1.4E-42 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS11930 f05a4430ed6e57df7a63d85e879496fd 222 Gene3D G3DSA:3.50.30.40 19 194 1.1E-51 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CVS48_RS15920 185282c28abb162b63d427ff0266dd26 259 Gene3D G3DSA:3.40.50.300 1 221 5.8E-69 T 29-03-2018 CVS48_RS15920 185282c28abb162b63d427ff0266dd26 259 SMART SM00382 30 211 3.8E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS15920 185282c28abb162b63d427ff0266dd26 259 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS15920 185282c28abb162b63d427ff0266dd26 259 Pfam PF00005 ABC transporter 21 161 8.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS15920 185282c28abb162b63d427ff0266dd26 259 SUPERFAMILY SSF52540 5 230 6.39E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS25635 1fe0297ed598780d1754e8560eddc812 671 SUPERFAMILY SSF55874 524 644 7.74E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25635 1fe0297ed598780d1754e8560eddc812 671 SUPERFAMILY SSF49785 74 180 6.8E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like CVS48_RS25635 1fe0297ed598780d1754e8560eddc812 671 Pfam PF07695 7TM diverse intracellular signalling 217 402 5.0E-13 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CVS48_RS25635 1fe0297ed598780d1754e8560eddc812 671 Gene3D G3DSA:3.30.565.10 408 653 4.8E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS25635 1fe0297ed598780d1754e8560eddc812 671 Gene3D G3DSA:2.60.120.260 49 214 1.0E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like CVS48_RS25635 1fe0297ed598780d1754e8560eddc812 671 SMART SM00387 552 647 9.9E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12310 b6fd577c14d7651bbfba9d8fb3da4ded 217 SUPERFAMILY SSF51197 20 215 7.0E-58 T 29-03-2018 CVS48_RS12310 b6fd577c14d7651bbfba9d8fb3da4ded 217 Gene3D G3DSA:2.60.120.590 15 217 6.6E-47 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CVS48_RS12310 b6fd577c14d7651bbfba9d8fb3da4ded 217 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 41 214 3.2E-52 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CVS48_RS05835 94f26f4fcecf6a0f57962f5e9b322bce 135 SUPERFAMILY SSF55298 10 117 4.24E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS05835 94f26f4fcecf6a0f57962f5e9b322bce 135 Gene3D G3DSA:3.30.1330.40 4 122 9.9E-20 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS05835 94f26f4fcecf6a0f57962f5e9b322bce 135 Pfam PF01042 Endoribonuclease L-PSP 11 116 4.6E-18 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS15005 8134253d9e1c4b8684fe469f6aeb3bde 518 Pfam PF12792 CSS motif domain associated with EAL 51 144 8.7E-12 T 29-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain CVS48_RS15005 8134253d9e1c4b8684fe469f6aeb3bde 518 Gene3D G3DSA:3.20.20.450 267 518 1.5E-65 T 29-03-2018 IPR001633 EAL domain CVS48_RS15005 8134253d9e1c4b8684fe469f6aeb3bde 518 SMART SM00052 265 510 3.0E-60 T 29-03-2018 IPR001633 EAL domain CVS48_RS15005 8134253d9e1c4b8684fe469f6aeb3bde 518 SUPERFAMILY SSF141868 272 514 7.85E-62 T 29-03-2018 IPR001633 EAL domain CVS48_RS15005 8134253d9e1c4b8684fe469f6aeb3bde 518 Pfam PF00563 EAL domain 273 505 1.5E-53 T 29-03-2018 IPR001633 EAL domain CVS48_RS22185 5656329f69c39cd89c1b6d85a1f19edf 298 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 11 297 3.2E-71 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CVS48_RS22185 5656329f69c39cd89c1b6d85a1f19edf 298 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 9 293 9.2E-123 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 CVS48_RS22185 5656329f69c39cd89c1b6d85a1f19edf 298 Pfam PF05175 Methyltransferase small domain 130 213 8.3E-17 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CVS48_RS22185 5656329f69c39cd89c1b6d85a1f19edf 298 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 2 298 52.325 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 CVS48_RS22185 5656329f69c39cd89c1b6d85a1f19edf 298 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 202 208 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CVS48_RS22185 5656329f69c39cd89c1b6d85a1f19edf 298 SUPERFAMILY SSF53335 12 265 3.38E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS22185 5656329f69c39cd89c1b6d85a1f19edf 298 PIRSF PIRSF037167 1 298 7.1E-129 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 CVS48_RS22185 5656329f69c39cd89c1b6d85a1f19edf 298 Gene3D G3DSA:3.40.50.150 99 277 1.0E-38 T 29-03-2018 CVS48_RS22185 5656329f69c39cd89c1b6d85a1f19edf 298 Gene3D G3DSA:1.10.8.10 10 98 4.7E-14 T 29-03-2018 CVS48_RS08050 c61ad9c3d40df04c7deacb23072efae5 637 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 137 604 56.058 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CVS48_RS08050 c61ad9c3d40df04c7deacb23072efae5 637 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 137 602 2.1E-212 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CVS48_RS08050 c61ad9c3d40df04c7deacb23072efae5 637 Pfam PF01964 Radical SAM ThiC family 139 598 1.7E-197 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CVS48_RS08050 c61ad9c3d40df04c7deacb23072efae5 637 Pfam PF13667 ThiC-associated domain 21 98 1.7E-32 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CVS48_RS13405 3f85cbcbb46b33d9bf6c3923f38c3456 151 Gene3D G3DSA:3.90.1590.10 1 150 5.5E-38 T 29-03-2018 CVS48_RS13405 3f85cbcbb46b33d9bf6c3923f38c3456 151 SUPERFAMILY SSF51316 14 148 4.71E-41 T 29-03-2018 IPR011057 Mss4-like CVS48_RS13405 3f85cbcbb46b33d9bf6c3923f38c3456 151 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 40 130 5.7E-24 T 29-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CVS48_RS14685 4c1afc2d8ba594f2d3508b7755586d98 384 PIRSF PIRSF006004 4 376 8.1E-144 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS14685 4c1afc2d8ba594f2d3508b7755586d98 384 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 6 362 71.9 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS14685 4c1afc2d8ba594f2d3508b7755586d98 384 Gene3D G3DSA:3.20.20.70 15 369 1.8E-40 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS14685 4c1afc2d8ba594f2d3508b7755586d98 384 Pfam PF04055 Radical SAM superfamily 110 290 1.0E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS14685 4c1afc2d8ba594f2d3508b7755586d98 384 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 5 367 1.4E-131 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CVS48_RS14685 4c1afc2d8ba594f2d3508b7755586d98 384 SUPERFAMILY SSF102114 104 321 1.02E-12 T 29-03-2018 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 SUPERFAMILY SSF53795 249 616 4.35E-154 T 29-03-2018 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 Gene3D G3DSA:3.40.449.10 9 248 8.0E-114 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 249 616 7.9E-167 T 29-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 SUPERFAMILY SSF68923 12 248 2.09E-101 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 273 281 - T 29-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 25 245 1.6E-103 T 29-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 PIRSF PIRSF001348 7 618 6.5E-279 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 14 617 51.304 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 Gene3D G3DSA:3.90.228.20 330 618 5.0E-119 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CVS48_RS15665 4066d62f827ca84d2a56d7f4e90e82db 618 Gene3D G3DSA:3.90.228.20 249 323 4.8E-22 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CVS48_RS20705 e856c51297844efe75d8766c3875f446 294 Pfam PF03466 LysR substrate binding domain 88 292 4.4E-40 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20705 e856c51297844efe75d8766c3875f446 294 SUPERFAMILY SSF53850 90 292 1.12E-41 T 29-03-2018 CVS48_RS20705 e856c51297844efe75d8766c3875f446 294 Gene3D G3DSA:3.40.190.10 174 262 7.5E-26 T 29-03-2018 CVS48_RS20705 e856c51297844efe75d8766c3875f446 294 Gene3D G3DSA:1.10.10.10 3 84 4.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20705 e856c51297844efe75d8766c3875f446 294 Gene3D G3DSA:3.40.190.10 89 173 6.6E-11 T 29-03-2018 CVS48_RS20705 e856c51297844efe75d8766c3875f446 294 SUPERFAMILY SSF46785 5 86 1.17E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20705 e856c51297844efe75d8766c3875f446 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 6.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11700 a4cc02195c5a111824e0ab2e5bb046a6 796 Gene3D G3DSA:2.40.170.20 271 796 3.1E-61 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS11700 a4cc02195c5a111824e0ab2e5bb046a6 796 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 779 796 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS11700 a4cc02195c5a111824e0ab2e5bb046a6 796 Gene3D G3DSA:2.170.130.10 111 270 7.5E-25 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS11700 a4cc02195c5a111824e0ab2e5bb046a6 796 SMART SM00965 61 112 7.4E-11 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS11700 a4cc02195c5a111824e0ab2e5bb046a6 796 Pfam PF07715 TonB-dependent Receptor Plug Domain 157 255 5.8E-16 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS11700 a4cc02195c5a111824e0ab2e5bb046a6 796 SUPERFAMILY SSF56935 113 796 4.01E-103 T 29-03-2018 CVS48_RS11700 a4cc02195c5a111824e0ab2e5bb046a6 796 Pfam PF07660 Secretin and TonB N terminus short domain 64 110 4.7E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS11700 a4cc02195c5a111824e0ab2e5bb046a6 796 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 158 796 6.9E-103 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS11700 a4cc02195c5a111824e0ab2e5bb046a6 796 Pfam PF00593 TonB dependent receptor 372 794 8.1E-34 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS02710 24d32dc225a2910d90fad334df9fe0df 347 Gene3D G3DSA:1.10.3470.10 13 346 4.3E-73 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS02710 24d32dc225a2910d90fad334df9fe0df 347 Pfam PF01032 FecCD transport family 30 343 5.5E-87 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CVS48_RS02710 24d32dc225a2910d90fad334df9fe0df 347 SUPERFAMILY SSF81345 11 344 1.57E-80 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 285 1.2E-62 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 6 286 39.524 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 3.9E-18 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 3.9E-18 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 3.9E-18 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 3.9E-18 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 Gene3D G3DSA:3.20.20.70 4 297 1.8E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 SUPERFAMILY SSF51569 8 288 6.07E-73 T 29-03-2018 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 136 166 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 SMART SM01130 6 288 4.9E-81 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 Pfam PF00701 Dihydrodipicolinate synthetase family 7 286 7.2E-60 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 PIRSF PIRSF001365 3 296 7.4E-69 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS00335 162556d0e4eee39a9a4b50d4d32b0e1e 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 42 59 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CVS48_RS13035 ca441864dc8e201265359b3e479deb06 193 PIRSF PIRSF036382 1 191 9.8E-53 T 29-03-2018 IPR008327 Signal transduction response regulator, antiterminator CVS48_RS13035 ca441864dc8e201265359b3e479deb06 193 Gene3D G3DSA:3.40.50.2300 1 137 2.2E-16 T 29-03-2018 CVS48_RS13035 ca441864dc8e201265359b3e479deb06 193 SUPERFAMILY SSF52172 1 184 7.68E-43 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS13035 ca441864dc8e201265359b3e479deb06 193 Pfam PF03861 ANTAR domain 133 184 3.4E-17 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CVS48_RS13035 ca441864dc8e201265359b3e479deb06 193 Pfam PF00072 Response regulator receiver domain 5 104 3.5E-8 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS13035 ca441864dc8e201265359b3e479deb06 193 SMART SM01012 129 184 3.6E-19 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CVS48_RS13035 ca441864dc8e201265359b3e479deb06 193 Gene3D G3DSA:1.10.10.10 138 186 1.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13035 ca441864dc8e201265359b3e479deb06 193 SMART SM00448 2 113 0.0045 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS24940 281c2ad3f03972147827a610410ca590 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 328 3.5E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS24940 281c2ad3f03972147827a610410ca590 332 PIRSF PIRSF017082 1 332 7.5E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS24940 281c2ad3f03972147827a610410ca590 332 SUPERFAMILY SSF53850 124 291 1.78E-12 T 29-03-2018 CVS48_RS24940 281c2ad3f03972147827a610410ca590 332 Gene3D G3DSA:3.40.190.10 132 321 2.1E-8 T 29-03-2018 CVS48_RS21330 6415eae358949e9fc9dbb141948933ed 395 SUPERFAMILY SSF53335 129 385 5.79E-78 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS21330 6415eae358949e9fc9dbb141948933ed 395 Pfam PF02353 Mycolic acid cyclopropane synthetase 120 380 3.7E-94 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS21330 6415eae358949e9fc9dbb141948933ed 395 PIRSF PIRSF003085 24 394 3.4E-122 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CVS48_RS21330 6415eae358949e9fc9dbb141948933ed 395 Gene3D G3DSA:3.40.50.150 117 384 5.0E-63 T 29-03-2018 CVS48_RS17820 370e899f06ccbae9b7238c2943c08291 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 316 2.2E-66 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17820 370e899f06ccbae9b7238c2943c08291 324 PIRSF PIRSF017082 1 321 4.6E-69 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17820 370e899f06ccbae9b7238c2943c08291 324 SUPERFAMILY SSF53850 105 284 5.09E-13 T 29-03-2018 CVS48_RS17820 370e899f06ccbae9b7238c2943c08291 324 Gene3D G3DSA:3.40.190.10 38 292 3.3E-9 T 29-03-2018 CVS48_RS16255 405430a620f8101ca9bfe345c9dada60 292 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 19 59 2.0E-12 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS16255 405430a620f8101ca9bfe345c9dada60 292 SUPERFAMILY SSF161098 85 278 2.62E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS16255 405430a620f8101ca9bfe345c9dada60 292 Gene3D G3DSA:1.10.3720.10 16 280 1.4E-52 T 29-03-2018 CVS48_RS16255 405430a620f8101ca9bfe345c9dada60 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 290 4.6E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS12170 da0df3cecfe5ee231731a33d97d9ba8b 389 Gene3D G3DSA:1.20.1250.20 188 371 3.9E-17 T 29-03-2018 CVS48_RS12170 da0df3cecfe5ee231731a33d97d9ba8b 389 Gene3D G3DSA:1.20.1250.20 1 176 4.0E-13 T 29-03-2018 CVS48_RS12170 da0df3cecfe5ee231731a33d97d9ba8b 389 Pfam PF07690 Major Facilitator Superfamily 11 330 1.7E-18 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS12170 da0df3cecfe5ee231731a33d97d9ba8b 389 SUPERFAMILY SSF103473 7 370 4.58E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS07005 4aed40133792a3b0bf6a87b02559cbf8 299 SUPERFAMILY SSF53448 4 274 4.69E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS07005 4aed40133792a3b0bf6a87b02559cbf8 299 Gene3D G3DSA:3.90.550.10 2 267 1.0E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS07005 4aed40133792a3b0bf6a87b02559cbf8 299 Pfam PF00535 Glycosyl transferase family 2 6 192 1.8E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS20625 58c1ed61bace720bdf2f3061f4272c79 328 PIRSF PIRSF017082 1 327 4.7E-85 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS20625 58c1ed61bace720bdf2f3061f4272c79 328 Gene3D G3DSA:3.40.190.10 128 239 9.1E-10 T 29-03-2018 CVS48_RS20625 58c1ed61bace720bdf2f3061f4272c79 328 SUPERFAMILY SSF53850 119 280 6.76E-9 T 29-03-2018 CVS48_RS20625 58c1ed61bace720bdf2f3061f4272c79 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 323 6.7E-75 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13755 0d225369dc7f48ef772dd6f3122cc075 264 Gene3D G3DSA:1.10.3720.10 11 257 4.7E-27 T 29-03-2018 CVS48_RS13755 0d225369dc7f48ef772dd6f3122cc075 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 251 4.4E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13755 0d225369dc7f48ef772dd6f3122cc075 264 SUPERFAMILY SSF161098 60 243 1.06E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 Gene3D G3DSA:3.40.50.720 4 255 3.1E-75 T 29-03-2018 CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 5.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 5.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 253 9.4E-62 T 29-03-2018 CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 6.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 6.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 6.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 6.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 6.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 191 4.6E-4 T 29-03-2018 CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS08700 20d340ef99437ce26cba90c5800308bd 255 SUPERFAMILY SSF51735 9 254 4.94E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 307 328 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 SUPERFAMILY SSF109998 42 166 1.55E-32 T 29-03-2018 IPR027304 Trigger factor/SurA domain CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 SUPERFAMILY SSF109998 200 236 1.55E-32 T 29-03-2018 IPR027304 Trigger factor/SurA domain CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 Gene3D G3DSA:3.10.50.40 256 394 2.5E-40 T 29-03-2018 CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 Gene3D G3DSA:3.10.50.40 396 520 0.0035 T 29-03-2018 CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 Gene3D G3DSA:3.10.50.40 521 615 0.49 T 29-03-2018 CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 Pfam PF13616 PPIC-type PPIASE domain 259 369 1.6E-26 T 29-03-2018 CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 Pfam PF13624 SurA N-terminal domain 1 162 7.7E-47 T 29-03-2018 CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 Gene3D G3DSA:1.10.4030.10 36 166 5.7E-24 T 29-03-2018 CVS48_RS19725 d1f87bd664e355b868edaebd4698c0db 654 SUPERFAMILY SSF54534 258 368 8.5E-29 T 29-03-2018 CVS48_RS02720 804ad9dcc60363615eea56366ec260ce 165 Pfam PF04073 Aminoacyl-tRNA editing domain 36 152 1.1E-26 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS02720 804ad9dcc60363615eea56366ec260ce 165 Gene3D G3DSA:3.90.960.10 4 163 7.8E-34 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS02720 804ad9dcc60363615eea56366ec260ce 165 SUPERFAMILY SSF55826 14 161 7.85E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS15555 d69d6bfddb0e34e04e1e2bd72dd0ba7c 152 SUPERFAMILY SSF46785 7 145 1.34E-40 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15555 d69d6bfddb0e34e04e1e2bd72dd0ba7c 152 Gene3D G3DSA:1.10.10.10 2 151 3.7E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15555 d69d6bfddb0e34e04e1e2bd72dd0ba7c 152 Pfam PF01638 HxlR-like helix-turn-helix 21 104 9.6E-19 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CVS48_RS01345 2bee7f4c0c6d43e35e7595812fbd0f22 140 Gene3D G3DSA:3.10.450.50 6 132 1.2E-17 T 29-03-2018 CVS48_RS01345 2bee7f4c0c6d43e35e7595812fbd0f22 140 SUPERFAMILY SSF54427 2 123 4.81E-31 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS01345 2bee7f4c0c6d43e35e7595812fbd0f22 140 Pfam PF13474 SnoaL-like domain 10 124 5.6E-15 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CVS48_RS08545 5f4fe83ee83a9294e7aaf4c4468b5a86 574 PIRSF PIRSF028304 1 574 9.5E-145 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CVS48_RS08545 5f4fe83ee83a9294e7aaf4c4468b5a86 574 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 2 573 6.6E-148 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CVS48_RS08545 5f4fe83ee83a9294e7aaf4c4468b5a86 574 Pfam PF05947 Type VI secretion system, TssF 4 571 4.4E-163 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CVS48_RS12455 fb391665d8c592a818f85addcc5a1fa4 302 PIRSF PIRSF000292 2 299 4.6E-130 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CVS48_RS12455 fb391665d8c592a818f85addcc5a1fa4 302 Pfam PF06481 COX Aromatic Rich Motif 237 281 1.8E-11 T 29-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 CVS48_RS12455 fb391665d8c592a818f85addcc5a1fa4 302 SUPERFAMILY SSF49503 121 278 1.22E-49 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS12455 fb391665d8c592a818f85addcc5a1fa4 302 Gene3D G3DSA:1.10.287.90 27 112 8.5E-20 T 29-03-2018 CVS48_RS12455 fb391665d8c592a818f85addcc5a1fa4 302 SUPERFAMILY SSF81464 28 116 2.94E-23 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12455 fb391665d8c592a818f85addcc5a1fa4 302 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 148 218 5.8E-5 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12455 fb391665d8c592a818f85addcc5a1fa4 302 Gene3D G3DSA:2.60.40.420 113 278 1.0E-49 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS12455 fb391665d8c592a818f85addcc5a1fa4 302 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 16 237 1.6E-114 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CVS48_RS24625 7753fe3b92bc0553cff2b52153a127d5 308 Gene3D G3DSA:3.90.1530.10 1 116 3.3E-5 T 29-03-2018 CVS48_RS24625 7753fe3b92bc0553cff2b52153a127d5 308 SUPERFAMILY SSF109709 116 196 2.35E-10 T 29-03-2018 CVS48_RS12360 db878182619b8c448104d9c14e181884 320 Pfam PF03466 LysR substrate binding domain 90 289 2.3E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS12360 db878182619b8c448104d9c14e181884 320 SUPERFAMILY SSF53850 90 288 4.15E-37 T 29-03-2018 CVS48_RS12360 db878182619b8c448104d9c14e181884 320 Gene3D G3DSA:3.40.190.10 90 177 4.0E-24 T 29-03-2018 CVS48_RS12360 db878182619b8c448104d9c14e181884 320 SUPERFAMILY SSF46785 1 113 1.22E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12360 db878182619b8c448104d9c14e181884 320 Gene3D G3DSA:3.40.190.10 178 269 4.6E-20 T 29-03-2018 CVS48_RS12360 db878182619b8c448104d9c14e181884 320 Gene3D G3DSA:1.10.10.10 1 87 3.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12360 db878182619b8c448104d9c14e181884 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.9E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18900 4f0c905f7669478368be9e6eb5e566e7 106 Gene3D G3DSA:3.40.30.10 2 100 2.3E-41 T 29-03-2018 CVS48_RS18900 4f0c905f7669478368be9e6eb5e566e7 106 Pfam PF10262 Rdx family 9 82 3.5E-34 T 29-03-2018 IPR011893 Selenoprotein, Rdx type CVS48_RS18900 4f0c905f7669478368be9e6eb5e566e7 106 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 10 81 2.0E-20 T 29-03-2018 IPR011893 Selenoprotein, Rdx type CVS48_RS18900 4f0c905f7669478368be9e6eb5e566e7 106 SUPERFAMILY SSF52833 7 91 1.14E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS08280 95fb832da113db6560da424efabf304f 481 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 31 236 4.5E-17 T 29-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 CVS48_RS01095 31a3f06ce917a7a134e9a20f64e16cd7 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 66 8.5E-15 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CVS48_RS01095 31a3f06ce917a7a134e9a20f64e16cd7 83 Gene3D G3DSA:3.40.1620.10 1 48 1.8E-16 T 29-03-2018 CVS48_RS01095 31a3f06ce917a7a134e9a20f64e16cd7 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 55 1.3E-10 T 29-03-2018 CVS48_RS01095 31a3f06ce917a7a134e9a20f64e16cd7 83 SUPERFAMILY SSF143120 1 63 9.29E-14 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CVS48_RS22945 d916169ff23464b7ccc9e2eb0f0f9ada 117 PIRSF PIRSF028139 2 117 1.4E-37 T 29-03-2018 IPR014980 Dopa 4,5-dioxygenase CVS48_RS22945 d916169ff23464b7ccc9e2eb0f0f9ada 117 Gene3D G3DSA:3.30.70.1240 4 115 4.8E-40 T 29-03-2018 IPR023389 DOPA-like domain CVS48_RS22945 d916169ff23464b7ccc9e2eb0f0f9ada 117 Pfam PF08883 Dopa 4,5-dioxygenase family 12 113 6.8E-33 T 29-03-2018 IPR014980 Dopa 4,5-dioxygenase CVS48_RS22945 d916169ff23464b7ccc9e2eb0f0f9ada 117 SUPERFAMILY SSF143410 2 114 3.27E-41 T 29-03-2018 IPR023389 DOPA-like domain CVS48_RS11705 5ec6a3ca8fa64eab746c95da4d6de6bc 302 SUPERFAMILY SSF103481 189 287 4.19E-13 T 29-03-2018 CVS48_RS11705 5ec6a3ca8fa64eab746c95da4d6de6bc 302 Pfam PF00892 EamA-like transporter family 7 138 1.1E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS11705 5ec6a3ca8fa64eab746c95da4d6de6bc 302 Pfam PF00892 EamA-like transporter family 153 285 4.8E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS11705 5ec6a3ca8fa64eab746c95da4d6de6bc 302 SUPERFAMILY SSF103481 39 141 8.24E-14 T 29-03-2018 CVS48_RS11545 cc842a73f7a5800dafc90385563472fe 323 SUPERFAMILY SSF52283 18 147 1.68E-28 T 29-03-2018 CVS48_RS11545 cc842a73f7a5800dafc90385563472fe 323 Gene3D G3DSA:3.40.50.720 15 127 4.2E-26 T 29-03-2018 CVS48_RS11545 cc842a73f7a5800dafc90385563472fe 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 123 300 1.0E-54 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS11545 cc842a73f7a5800dafc90385563472fe 323 Gene3D G3DSA:3.40.50.720 128 303 3.1E-54 T 29-03-2018 CVS48_RS11545 cc842a73f7a5800dafc90385563472fe 323 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 210 232 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CVS48_RS11545 cc842a73f7a5800dafc90385563472fe 323 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 239 255 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CVS48_RS11545 cc842a73f7a5800dafc90385563472fe 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 322 1.2E-24 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CVS48_RS11545 cc842a73f7a5800dafc90385563472fe 323 SUPERFAMILY SSF51735 113 301 1.11E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09090 3876038ecf14326dbbc9e9be18eba09e 108 Pfam PF00462 Glutaredoxin 17 82 3.6E-18 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CVS48_RS09090 3876038ecf14326dbbc9e9be18eba09e 108 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 102 9.9E-45 T 29-03-2018 IPR004480 Monothiol glutaredoxin-related CVS48_RS09090 3876038ecf14326dbbc9e9be18eba09e 108 SUPERFAMILY SSF52833 1 106 1.16E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS09090 3876038ecf14326dbbc9e9be18eba09e 108 PIRSF PIRSF005894 1 108 4.4E-48 T 29-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 CVS48_RS09090 3876038ecf14326dbbc9e9be18eba09e 108 Gene3D G3DSA:3.40.30.10 2 108 6.1E-32 T 29-03-2018 CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 Gene3D G3DSA:3.40.190.10 88 176 3.3E-18 T 29-03-2018 CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 9.3E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 Gene3D G3DSA:3.40.190.10 177 266 3.6E-21 T 29-03-2018 CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.8E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.8E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.8E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 Pfam PF03466 LysR substrate binding domain 88 291 1.8E-40 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 SUPERFAMILY SSF53850 90 291 1.09E-38 T 29-03-2018 CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 Gene3D G3DSA:1.10.10.10 1 83 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14265 c346a1b109452572f3c269d1018a0b1a 308 SUPERFAMILY SSF46785 1 85 1.18E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01530 df1b1a6963749ac1ca3250d90585acf9 329 Gene3D G3DSA:3.40.50.300 3 328 2.4E-82 T 29-03-2018 CVS48_RS01530 df1b1a6963749ac1ca3250d90585acf9 329 SMART SM00382 46 238 1.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01530 df1b1a6963749ac1ca3250d90585acf9 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 322 2.0E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS01530 df1b1a6963749ac1ca3250d90585acf9 329 SUPERFAMILY SSF52540 28 260 1.5E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01530 df1b1a6963749ac1ca3250d90585acf9 329 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS01530 df1b1a6963749ac1ca3250d90585acf9 329 Pfam PF00005 ABC transporter 38 189 2.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS01530 df1b1a6963749ac1ca3250d90585acf9 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 304 9.7E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS14410 fd89e93c6829fc9a5a265da93c22bab7 293 Pfam PF13557 Putative MetA-pathway of phenol degradation 67 289 7.0E-25 T 29-03-2018 IPR025737 MetA-pathway of phenol degradation, putative CVS48_RS14500 bcccca4eb9727f5463060a7db120e6fc 448 Gene3D G3DSA:3.90.1150.10 178 255 0.0017 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS14500 bcccca4eb9727f5463060a7db120e6fc 448 PIRSF PIRSF000521 17 439 5.9E-36 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS14500 bcccca4eb9727f5463060a7db120e6fc 448 SUPERFAMILY SSF53383 5 438 3.19E-128 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS14500 bcccca4eb9727f5463060a7db120e6fc 448 Gene3D G3DSA:3.90.1150.10 256 440 1.5E-51 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS14500 bcccca4eb9727f5463060a7db120e6fc 448 Gene3D G3DSA:3.90.1150.10 2 177 3.0E-46 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS14500 bcccca4eb9727f5463060a7db120e6fc 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS14500 bcccca4eb9727f5463060a7db120e6fc 448 Pfam PF00202 Aminotransferase class-III 12 436 2.8E-104 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS10020 d4d0c3325ab746148201966d7838b575 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 268 1.8E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10020 d4d0c3325ab746148201966d7838b575 284 Gene3D G3DSA:1.10.3720.10 9 281 1.2E-38 T 29-03-2018 CVS48_RS10020 d4d0c3325ab746148201966d7838b575 284 SUPERFAMILY SSF161098 10 273 1.03E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27105 da8ed1b5ad66cfe3a8043acba48cccee 553 Gene3D G3DSA:1.20.58.220 445 542 6.7E-5 T 29-03-2018 CVS48_RS27105 da8ed1b5ad66cfe3a8043acba48cccee 553 SUPERFAMILY SSF109755 332 543 6.93E-22 T 29-03-2018 CVS48_RS27105 da8ed1b5ad66cfe3a8043acba48cccee 553 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 5 307 2.8E-64 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CVS48_RS27105 da8ed1b5ad66cfe3a8043acba48cccee 553 Gene3D G3DSA:1.20.58.220 328 436 1.3E-8 T 29-03-2018 CVS48_RS27105 da8ed1b5ad66cfe3a8043acba48cccee 553 Pfam PF02690 Na+/Pi-cotransporter 163 246 6.0E-11 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CVS48_RS27105 da8ed1b5ad66cfe3a8043acba48cccee 553 Pfam PF02690 Na+/Pi-cotransporter 16 150 3.5E-34 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CVS48_RS12855 c23969337e7f9543e7163fb5343420e6 173 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 7 166 4.9E-80 T 29-03-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 CVS48_RS12855 c23969337e7f9543e7163fb5343420e6 173 Gene3D G3DSA:3.40.980.10 3 169 5.2E-36 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS12855 c23969337e7f9543e7163fb5343420e6 173 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 9 149 8.6E-39 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS12855 c23969337e7f9543e7163fb5343420e6 173 SMART SM00852 12 156 6.9E-32 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS12855 c23969337e7f9543e7163fb5343420e6 173 Pfam PF00994 Probable molybdopterin binding domain 12 153 2.5E-35 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS12855 c23969337e7f9543e7163fb5343420e6 173 PIRSF PIRSF006443 1 164 4.9E-65 T 29-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 CVS48_RS12855 c23969337e7f9543e7163fb5343420e6 173 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 70 83 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CVS48_RS12855 c23969337e7f9543e7163fb5343420e6 173 SUPERFAMILY SSF53218 8 166 3.01E-46 T 29-03-2018 IPR001453 MoaB/Mog domain CVS48_RS07085 defc2f6ef5dd28926718fd783ae2934d 395 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 27 387 2.4E-161 T 29-03-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family CVS48_RS07085 defc2f6ef5dd28926718fd783ae2934d 395 Gene3D G3DSA:3.90.1150.10 277 394 2.0E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS07085 defc2f6ef5dd28926718fd783ae2934d 395 Gene3D G3DSA:3.40.640.10 27 276 3.2E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS07085 defc2f6ef5dd28926718fd783ae2934d 395 SUPERFAMILY SSF53383 34 391 3.09E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS07085 defc2f6ef5dd28926718fd783ae2934d 395 PIRSF PIRSF000390 24 395 5.4E-94 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CVS48_RS07085 defc2f6ef5dd28926718fd783ae2934d 395 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 38 393 1.6E-91 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CVS48_RS26140 7966d93cb692a1ea939d0a2fae822f64 384 Gene3D G3DSA:3.40.50.2000 182 361 1.1E-33 T 29-03-2018 CVS48_RS26140 7966d93cb692a1ea939d0a2fae822f64 384 SUPERFAMILY SSF53756 13 377 5.38E-60 T 29-03-2018 CVS48_RS26140 7966d93cb692a1ea939d0a2fae822f64 384 Pfam PF13692 Glycosyl transferases group 1 211 342 7.3E-20 T 29-03-2018 CVS48_RS26140 7966d93cb692a1ea939d0a2fae822f64 384 Pfam PF13439 Glycosyltransferase Family 4 25 182 2.6E-13 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 Pfam PF00344 SecY translocase 74 412 5.6E-119 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 Gene3D G3DSA:1.10.3370.10 9 434 1.9E-165 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 21 39 1.4E-96 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 1.4E-96 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 175 198 1.4E-96 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 149 174 1.4E-96 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 1.4E-96 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 1.4E-96 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 1.4E-96 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 1.4E-96 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 73 93 1.4E-96 T 29-03-2018 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 PIRSF PIRSF004557 9 435 4.7E-127 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 ProSitePatterns PS00756 Protein secY signature 2. 168 185 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 8 428 29.817 T 29-03-2018 IPR026593 Protein translocase subunit SecY CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 SUPERFAMILY SSF103491 13 419 4.05E-135 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CVS48_RS06540 28c223f7e09dab01a7980dc64d3e6b05 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 18 424 1.0E-136 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CVS48_RS12505 77711cf50ef946ca3534014e908a29c5 347 Pfam PF03576 Peptidase family S58 29 339 6.1E-58 T 29-03-2018 IPR005321 Peptidase S58, DmpA CVS48_RS12505 77711cf50ef946ca3534014e908a29c5 347 Gene3D G3DSA:3.60.70.12 25 346 1.2E-104 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS12505 77711cf50ef946ca3534014e908a29c5 347 SUPERFAMILY SSF56266 28 342 3.79E-68 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CVS48_RS10915 4aa37d2d926bf7499ad408fd076b8438 57 Pfam PF07366 SnoaL-like polyketide cyclase 1 52 1.6E-12 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CVS48_RS10915 4aa37d2d926bf7499ad408fd076b8438 57 Gene3D G3DSA:3.10.450.50 1 55 2.7E-8 T 29-03-2018 CVS48_RS10915 4aa37d2d926bf7499ad408fd076b8438 57 SUPERFAMILY SSF54427 2 55 1.75E-12 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS15540 52daa147f6acea45e46ab5531b3c2667 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.5E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15540 52daa147f6acea45e46ab5531b3c2667 301 SUPERFAMILY SSF46785 4 110 2.16E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15540 52daa147f6acea45e46ab5531b3c2667 301 Gene3D G3DSA:3.40.190.10 162 263 3.7E-22 T 29-03-2018 CVS48_RS15540 52daa147f6acea45e46ab5531b3c2667 301 Pfam PF03466 LysR substrate binding domain 90 292 2.8E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS15540 52daa147f6acea45e46ab5531b3c2667 301 Gene3D G3DSA:1.10.10.10 3 86 1.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15540 52daa147f6acea45e46ab5531b3c2667 301 SUPERFAMILY SSF53850 90 293 1.03E-38 T 29-03-2018 CVS48_RS27090 39e51ef1a63ab0b2eb969d205c0c0b6d 284 Pfam PF00892 EamA-like transporter family 3 132 2.1E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS27090 39e51ef1a63ab0b2eb969d205c0c0b6d 284 Pfam PF00892 EamA-like transporter family 143 273 3.1E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS27090 39e51ef1a63ab0b2eb969d205c0c0b6d 284 SUPERFAMILY SSF103481 37 136 3.14E-12 T 29-03-2018 CVS48_RS27090 39e51ef1a63ab0b2eb969d205c0c0b6d 284 SUPERFAMILY SSF103481 178 279 1.57E-9 T 29-03-2018 CVS48_RS24205 56f3060105bc65798b80f2a67d4a4b89 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.3E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS24205 56f3060105bc65798b80f2a67d4a4b89 300 SUPERFAMILY SSF53850 90 297 4.34E-48 T 29-03-2018 CVS48_RS24205 56f3060105bc65798b80f2a67d4a4b89 300 Gene3D G3DSA:3.40.190.10 89 176 2.9E-17 T 29-03-2018 CVS48_RS24205 56f3060105bc65798b80f2a67d4a4b89 300 Gene3D G3DSA:1.10.10.10 1 87 3.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24205 56f3060105bc65798b80f2a67d4a4b89 300 SUPERFAMILY SSF46785 2 112 3.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24205 56f3060105bc65798b80f2a67d4a4b89 300 Gene3D G3DSA:3.40.190.10 177 265 2.7E-30 T 29-03-2018 CVS48_RS24205 56f3060105bc65798b80f2a67d4a4b89 300 Pfam PF03466 LysR substrate binding domain 89 294 7.7E-46 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS08870 f54c76c38792f2112c1571f0059d26c8 325 SUPERFAMILY SSF52540 5 183 4.77E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08870 f54c76c38792f2112c1571f0059d26c8 325 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 230 314 4.8E-10 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS08870 f54c76c38792f2112c1571f0059d26c8 325 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 186 2.0E-35 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CVS48_RS08870 f54c76c38792f2112c1571f0059d26c8 325 Gene3D G3DSA:3.30.1220.10 218 315 6.7E-9 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS08870 f54c76c38792f2112c1571f0059d26c8 325 SMART SM00833 228 325 5.9E-4 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS08870 f54c76c38792f2112c1571f0059d26c8 325 SUPERFAMILY SSF90002 232 314 7.32E-10 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CVS48_RS08870 f54c76c38792f2112c1571f0059d26c8 325 Gene3D G3DSA:3.40.50.300 2 201 1.2E-25 T 29-03-2018 CVS48_RS22965 31bbda591701999e6ac0cb0866481444 141 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 141 5.4E-18 T 29-03-2018 IPR005265 Uncharacterised protein family UPF0093 CVS48_RS22965 31bbda591701999e6ac0cb0866481444 141 PIRSF PIRSF004638 1 141 8.6E-23 T 29-03-2018 IPR005265 Uncharacterised protein family UPF0093 CVS48_RS16840 d9bb1c8aa2ce2a43be88b2c504dcbab7 1013 Pfam PF00448 SRP54-type protein, GTPase domain 406 597 3.4E-35 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS16840 d9bb1c8aa2ce2a43be88b2c504dcbab7 1013 SMART SM00382 403 576 1.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16840 d9bb1c8aa2ce2a43be88b2c504dcbab7 1013 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 268 492 2.3E-58 T 29-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 CVS48_RS16840 d9bb1c8aa2ce2a43be88b2c504dcbab7 1013 Gene3D G3DSA:3.40.50.300 400 600 3.6E-24 T 29-03-2018 CVS48_RS16840 d9bb1c8aa2ce2a43be88b2c504dcbab7 1013 SUPERFAMILY SSF52540 404 598 2.34E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16840 d9bb1c8aa2ce2a43be88b2c504dcbab7 1013 SMART SM00962 404 599 2.4E-58 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CVS48_RS15265 dd6441f82cc083754a65471f929c255a 303 SUPERFAMILY SSF103481 188 289 2.09E-9 T 29-03-2018 CVS48_RS15265 dd6441f82cc083754a65471f929c255a 303 SUPERFAMILY SSF103481 52 143 3.14E-13 T 29-03-2018 CVS48_RS15265 dd6441f82cc083754a65471f929c255a 303 Pfam PF00892 EamA-like transporter family 14 141 1.8E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS15265 dd6441f82cc083754a65471f929c255a 303 Pfam PF00892 EamA-like transporter family 154 286 7.3E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS25185 eb913de32eaee2b811260d4981007b6b 198 Gene3D G3DSA:3.30.920.30 1 48 6.9E-15 T 29-03-2018 CVS48_RS25185 eb913de32eaee2b811260d4981007b6b 198 SUPERFAMILY SSF47598 158 196 9.34E-6 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CVS48_RS25185 eb913de32eaee2b811260d4981007b6b 198 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 4 46 2.4E-14 T 29-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 CVS48_RS25185 eb913de32eaee2b811260d4981007b6b 198 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 72 191 2.5E-37 T 29-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system CVS48_RS25185 eb913de32eaee2b811260d4981007b6b 198 SUPERFAMILY SSF54786 1 49 1.33E-11 T 29-03-2018 CVS48_RS25185 eb913de32eaee2b811260d4981007b6b 198 Gene3D G3DSA:3.30.2390.10 71 134 1.5E-10 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like CVS48_RS25185 eb913de32eaee2b811260d4981007b6b 198 SUPERFAMILY SSF143100 70 128 1.44E-13 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like CVS48_RS25185 eb913de32eaee2b811260d4981007b6b 198 Gene3D G3DSA:1.10.1220.10 135 196 8.7E-8 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CVS48_RS15370 a3dfe61bd7bc50757b3b16f012bdf8e8 413 Gene3D G3DSA:3.30.70.270 213 383 1.8E-53 T 29-03-2018 CVS48_RS15370 a3dfe61bd7bc50757b3b16f012bdf8e8 413 SMART SM00267 209 380 1.2E-54 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS15370 a3dfe61bd7bc50757b3b16f012bdf8e8 413 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 221 379 7.3E-45 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS15370 a3dfe61bd7bc50757b3b16f012bdf8e8 413 SUPERFAMILY SSF55073 225 379 1.1E-47 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS15370 a3dfe61bd7bc50757b3b16f012bdf8e8 413 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 376 6.2E-42 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS25610 b492a39c1d8cd491664a7b111c089f28 207 Pfam PF01810 LysE type translocator 18 205 2.4E-27 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS25610 b492a39c1d8cd491664a7b111c089f28 207 PIRSF PIRSF006324 1 207 8.4E-42 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS18870 746ac0450cc09a1b2c04e86c0c0172b3 345 SUPERFAMILY SSF56935 30 345 1.68E-62 T 29-03-2018 CVS48_RS18870 746ac0450cc09a1b2c04e86c0c0172b3 345 Gene3D G3DSA:2.40.160.10 31 345 6.8E-60 T 29-03-2018 CVS48_RS18870 746ac0450cc09a1b2c04e86c0c0172b3 345 Pfam PF13609 Gram-negative porin 13 330 7.6E-53 T 29-03-2018 CVS48_RS25540 8ad3b3a2eda720094d403dfba97fd494 335 PIRSF PIRSF017082 1 335 8.7E-75 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25540 8ad3b3a2eda720094d403dfba97fd494 335 SUPERFAMILY SSF53850 107 280 1.3E-5 T 29-03-2018 CVS48_RS25540 8ad3b3a2eda720094d403dfba97fd494 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 328 2.2E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25540 8ad3b3a2eda720094d403dfba97fd494 335 Gene3D G3DSA:3.40.190.10 145 304 2.6E-7 T 29-03-2018 CVS48_RS12555 18c6ae819a5c1bf734a4f7c4cb8f3fb9 354 Pfam PF16220 Domain of unknown function (DUF4880) 23 65 1.4E-11 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS12555 18c6ae819a5c1bf734a4f7c4cb8f3fb9 354 Pfam PF04773 FecR protein 120 239 4.2E-12 T 29-03-2018 IPR006860 FecR protein CVS48_RS12555 18c6ae819a5c1bf734a4f7c4cb8f3fb9 354 PIRSF PIRSF018266 13 350 4.4E-83 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 Gene3D G3DSA:1.10.10.10 4 55 7.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 2.4E-17 T 29-03-2018 CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 SUPERFAMILY SSF46785 2 63 1.83E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.1E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.1E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.1E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 SUPERFAMILY SSF54909 63 148 1.61E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 Gene3D G3DSA:3.30.70.920 56 153 1.5E-23 T 29-03-2018 CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 2.2E-18 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS12515 cc7ab81e66d2be682ac85915c50692f0 157 SMART SM00344 3 112 3.3E-38 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS23990 d225da1bd3697e931a56f41665af8c4a 207 Pfam PF05995 Cysteine dioxygenase type I 73 158 1.2E-6 T 29-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CVS48_RS23990 d225da1bd3697e931a56f41665af8c4a 207 SUPERFAMILY SSF51182 10 195 6.36E-51 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS23990 d225da1bd3697e931a56f41665af8c4a 207 Gene3D G3DSA:2.60.120.10 3 196 7.2E-31 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SUPERFAMILY SSF48452 438 566 1.71E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 Pfam PF13432 Tetratricopeptide repeat 251 307 8.5E-4 T 29-03-2018 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 Pfam PF13432 Tetratricopeptide repeat 437 502 0.0028 T 29-03-2018 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 Pfam PF13432 Tetratricopeptide repeat 49 100 0.0028 T 29-03-2018 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 Pfam PF13283 Bacteriophage N adsorption protein A C-term 816 928 7.9E-25 T 29-03-2018 IPR025137 Bacteriophage N4 adsorption protein A, C-terminal CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SMART SM00028 162 195 240.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SMART SM00028 313 346 10.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SMART SM00028 279 312 250.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SMART SM00028 245 278 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SMART SM00028 502 535 62.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SMART SM00028 73 106 300.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SMART SM00028 432 465 37.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SMART SM00028 39 72 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SUPERFAMILY SSF48452 168 226 1.05E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SUPERFAMILY SSF48452 40 115 1.05E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 Gene3D G3DSA:1.25.40.10 239 352 4.3E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 SUPERFAMILY SSF48452 249 353 7.59E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 Gene3D G3DSA:1.25.40.10 353 572 2.1E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS27575 b3de65ea2bc18ef661c63d47286092de 934 Gene3D G3DSA:1.25.40.120 14 238 8.0E-17 T 29-03-2018 CVS48_RS21830 7f0dc02cca683cbcc2be96fb7a1fb7e3 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 5.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS21830 7f0dc02cca683cbcc2be96fb7a1fb7e3 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 5.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS21830 7f0dc02cca683cbcc2be96fb7a1fb7e3 221 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 65 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CVS48_RS21830 7f0dc02cca683cbcc2be96fb7a1fb7e3 221 SUPERFAMILY SSF48498 90 194 2.34E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS21830 7f0dc02cca683cbcc2be96fb7a1fb7e3 221 SUPERFAMILY SSF46689 15 94 3.49E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS21830 7f0dc02cca683cbcc2be96fb7a1fb7e3 221 Gene3D G3DSA:1.10.10.60 1 65 2.1E-17 T 29-03-2018 CVS48_RS21830 7f0dc02cca683cbcc2be96fb7a1fb7e3 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 8.0E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS21830 7f0dc02cca683cbcc2be96fb7a1fb7e3 221 Gene3D G3DSA:1.10.357.10 66 204 7.3E-17 T 29-03-2018 CVS48_RS21575 a079e4c57361d1fb0bb44e1efcad5ddc 546 Pfam PF00899 ThiF family 306 521 3.9E-16 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CVS48_RS21575 a079e4c57361d1fb0bb44e1efcad5ddc 546 Gene3D G3DSA:3.40.50.720 305 546 3.1E-22 T 29-03-2018 CVS48_RS21575 a079e4c57361d1fb0bb44e1efcad5ddc 546 SUPERFAMILY SSF69572 307 475 7.32E-17 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CVS48_RS16590 06d5f62ee600e4f3beb87959bd3bb9e1 277 Gene3D G3DSA:1.10.3470.10 1 269 2.0E-42 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS16590 06d5f62ee600e4f3beb87959bd3bb9e1 277 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 250 5.9E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS06450 06e34a343f35ef6a75400a633f671ae7 336 Gene3D G3DSA:1.10.3470.10 34 326 7.6E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS06450 06e34a343f35ef6a75400a633f671ae7 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 322 4.1E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 SMART SM00929 83 123 4.1E-20 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 SUPERFAMILY SSF54862 76 211 1.76E-35 T 29-03-2018 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 SUPERFAMILY SSF53706 214 654 2.05E-86 T 29-03-2018 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 Gene3D G3DSA:2.20.25.90 209 274 6.8E-4 T 29-03-2018 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 Gene3D G3DSA:3.40.50.740 425 661 2.1E-28 T 29-03-2018 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 SUPERFAMILY SSF54292 1 74 1.18E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 Gene3D G3DSA:3.40.50.740 275 419 4.4E-25 T 29-03-2018 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 Gene3D G3DSA:2.40.40.20 691 772 1.1E-4 T 29-03-2018 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 630 1.3E-200 T 29-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 121 1.9E-16 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 Gene3D G3DSA:3.10.20.30 1 161 8.7E-16 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 Pfam PF00384 Molybdopterin oxidoreductase 522 631 5.0E-12 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 Pfam PF00384 Molybdopterin oxidoreductase 273 413 2.8E-18 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28675 111db684b04af406a550e56c5b3cb4a7 775 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 74 2.0E-20 T 29-03-2018 CVS48_RS03775 69b22d58e3f18e6117b33ebd011c2a87 324 Pfam PF05275 Copper resistance protein B precursor (CopB) 119 324 1.5E-80 T 29-03-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 CVS48_RS03775 69b22d58e3f18e6117b33ebd011c2a87 324 Gene3D G3DSA:2.40.128.130 139 324 1.8E-6 T 29-03-2018 CVS48_RS00490 4a3e34797e9e86d765034ff1a796854f 263 SUPERFAMILY SSF52540 94 232 5.13E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00490 4a3e34797e9e86d765034ff1a796854f 263 Gene3D G3DSA:3.40.50.300 32 232 4.7E-13 T 29-03-2018 CVS48_RS00490 4a3e34797e9e86d765034ff1a796854f 263 PIRSF PIRSF003073 1 252 9.0E-75 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CVS48_RS00490 4a3e34797e9e86d765034ff1a796854f 263 Pfam PF01695 IstB-like ATP binding protein 54 229 3.6E-57 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CVS48_RS00490 4a3e34797e9e86d765034ff1a796854f 263 SMART SM00382 97 230 2.6E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS11655 a017253085e00f899fc396bc6d7afc1e 131 Pfam PF01850 PIN domain 2 125 2.0E-16 T 29-03-2018 IPR002716 PIN domain CVS48_RS11655 a017253085e00f899fc396bc6d7afc1e 131 Gene3D G3DSA:3.40.50.1010 1 130 5.3E-19 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS11655 a017253085e00f899fc396bc6d7afc1e 131 SUPERFAMILY SSF88723 1 124 1.96E-23 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS11655 a017253085e00f899fc396bc6d7afc1e 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 130 9.67 T 29-03-2018 IPR022907 VapC family GO:0004540 CVS48_RS06620 c47bdf5fcdf4fd14bebe9f24165683b8 441 Pfam PF01578 Cytochrome C assembly protein 179 436 2.3E-44 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CVS48_RS06620 c47bdf5fcdf4fd14bebe9f24165683b8 441 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 152 439 3.7E-74 T 29-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CVS48_RS28375 1fe73bab347b203f392609458dc093e3 325 SUPERFAMILY SSF55120 99 322 2.08E-65 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS28375 1fe73bab347b203f392609458dc093e3 325 SUPERFAMILY SSF55174 34 85 1.47E-8 T 29-03-2018 CVS48_RS28375 1fe73bab347b203f392609458dc093e3 325 SMART SM00363 35 93 3.0E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS28375 1fe73bab347b203f392609458dc093e3 325 Gene3D G3DSA:3.10.290.10 23 95 2.0E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS28375 1fe73bab347b203f392609458dc093e3 325 Pfam PF01479 S4 domain 35 81 6.3E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CVS48_RS28375 1fe73bab347b203f392609458dc093e3 325 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 32 322 1.4E-77 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS28375 1fe73bab347b203f392609458dc093e3 325 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 149 163 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS28375 1fe73bab347b203f392609458dc093e3 325 Gene3D G3DSA:3.30.2350.10 102 325 4.1E-67 T 29-03-2018 CVS48_RS28375 1fe73bab347b203f392609458dc093e3 325 Pfam PF00849 RNA pseudouridylate synthase 111 259 1.3E-30 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CVS48_RS18200 e61aa8a8dded35cbf0191e1878a66846 935 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 552 923 1.2E-53 T 29-03-2018 IPR007296 Domain of unknown function DUF403 CVS48_RS18200 e61aa8a8dded35cbf0191e1878a66846 935 SUPERFAMILY SSF56059 89 254 7.42E-23 T 29-03-2018 CVS48_RS18200 e61aa8a8dded35cbf0191e1878a66846 935 SUPERFAMILY SSF56059 368 492 7.42E-23 T 29-03-2018 CVS48_RS18200 e61aa8a8dded35cbf0191e1878a66846 935 Pfam PF14403 Circularly permuted ATP-grasp type 2 116 503 8.1E-149 T 29-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 CVS48_RS15440 6b02909695f60d93bb7c2c2c3f600774 195 SUPERFAMILY SSF89392 19 178 9.81E-12 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CVS48_RS15440 6b02909695f60d93bb7c2c2c3f600774 195 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 33 181 1.0E-6 T 29-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like CVS48_RS15440 6b02909695f60d93bb7c2c2c3f600774 195 Gene3D G3DSA:2.50.20.10 18 189 3.2E-17 T 29-03-2018 CVS48_RS14330 87d0921f66189fcd0bc3c24e9bb6c4ed 134 Pfam PF02410 Ribosomal silencing factor during starvation 9 104 2.7E-24 T 29-03-2018 CVS48_RS14330 87d0921f66189fcd0bc3c24e9bb6c4ed 134 SUPERFAMILY SSF81301 1 109 1.5E-34 T 29-03-2018 CVS48_RS14330 87d0921f66189fcd0bc3c24e9bb6c4ed 134 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 4.4E-32 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CVS48_RS14330 87d0921f66189fcd0bc3c24e9bb6c4ed 134 Gene3D G3DSA:3.30.460.10 1 119 1.4E-30 T 29-03-2018 CVS48_RS14330 87d0921f66189fcd0bc3c24e9bb6c4ed 134 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 23.063 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CVS48_RS10400 2cd7d0922a644fad00c3c9a65734f5cf 470 Gene3D G3DSA:3.90.1150.10 371 469 3.6E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS10400 2cd7d0922a644fad00c3c9a65734f5cf 470 Gene3D G3DSA:3.40.640.10 91 370 5.0E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS10400 2cd7d0922a644fad00c3c9a65734f5cf 470 Pfam PF00155 Aminotransferase class I and II 149 448 1.4E-30 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS10400 2cd7d0922a644fad00c3c9a65734f5cf 470 SUPERFAMILY SSF46785 2 74 3.81E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10400 2cd7d0922a644fad00c3c9a65734f5cf 470 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.3E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10400 2cd7d0922a644fad00c3c9a65734f5cf 470 SUPERFAMILY SSF53383 95 467 1.33E-92 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS10400 2cd7d0922a644fad00c3c9a65734f5cf 470 SMART SM00345 7 66 4.4E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS10400 2cd7d0922a644fad00c3c9a65734f5cf 470 Gene3D G3DSA:1.10.10.10 1 67 4.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05130 85d13e630c08ef35c17497dc6812e4e7 134 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 110 6.0E-25 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CVS48_RS05130 85d13e630c08ef35c17497dc6812e4e7 134 SUPERFAMILY SSF141734 6 114 7.06E-48 T 29-03-2018 CVS48_RS05130 85d13e630c08ef35c17497dc6812e4e7 134 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 111 33.093 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CVS48_RS05130 85d13e630c08ef35c17497dc6812e4e7 134 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 107 1.1E-35 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CVS48_RS03275 9f10ad8f3a720a0e0ae69c235cad6a1d 238 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 116 2.3E-21 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS03275 9f10ad8f3a720a0e0ae69c235cad6a1d 238 SUPERFAMILY SSF161098 22 214 7.19E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03275 9f10ad8f3a720a0e0ae69c235cad6a1d 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 222 6.8E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03275 9f10ad8f3a720a0e0ae69c235cad6a1d 238 Gene3D G3DSA:1.10.3720.10 7 228 1.9E-41 T 29-03-2018 CVS48_RS00575 745048534dbc0601d8b980050a8dccd8 409 PIRSF PIRSF004810 2 408 1.7E-123 T 29-03-2018 IPR014047 Chromate transporter, long chain CVS48_RS00575 745048534dbc0601d8b980050a8dccd8 409 TIGRFAM TIGR00937 2A51: chromate efflux transporter 26 402 3.6E-101 T 29-03-2018 IPR014047 Chromate transporter, long chain CVS48_RS00575 745048534dbc0601d8b980050a8dccd8 409 Pfam PF02417 Chromate transporter 21 186 4.0E-32 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CVS48_RS00575 745048534dbc0601d8b980050a8dccd8 409 Pfam PF02417 Chromate transporter 237 403 8.6E-30 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CVS48_RS04420 5de517ff0bb19145ad99e5db1e471afb 243 SUPERFAMILY SSF48613 9 226 4.45E-51 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CVS48_RS04420 5de517ff0bb19145ad99e5db1e471afb 243 SMART SM01236 78 181 6.8E-27 T 29-03-2018 CVS48_RS04420 5de517ff0bb19145ad99e5db1e471afb 243 Gene3D G3DSA:1.20.910.10 2 239 5.2E-44 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CVS48_RS04420 5de517ff0bb19145ad99e5db1e471afb 243 Pfam PF14518 Iron-containing redox enzyme 44 214 1.1E-35 T 29-03-2018 IPR028201 PqqC-like protein CVS48_RS21580 96b227ae58cd49d75ded86a528581c81 160 Pfam PF14464 Prokaryotic homologs of the JAB domain 32 137 2.1E-12 T 29-03-2018 IPR028090 JAB domain, prokaryotic CVS48_RS21580 96b227ae58cd49d75ded86a528581c81 160 Gene3D G3DSA:3.40.140.10 12 153 3.8E-15 T 29-03-2018 CVS48_RS21580 96b227ae58cd49d75ded86a528581c81 160 SUPERFAMILY SSF102712 35 117 3.92E-8 T 29-03-2018 CVS48_RS01490 0c57a4d7c77fa007ff218ff9a36ce41d 85 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 81 6.2E-31 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CVS48_RS01490 0c57a4d7c77fa007ff218ff9a36ce41d 85 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 83 19.231 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CVS48_RS01490 0c57a4d7c77fa007ff218ff9a36ce41d 85 SUPERFAMILY SSF55229 33 83 1.57E-15 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CVS48_RS01490 0c57a4d7c77fa007ff218ff9a36ce41d 85 Pfam PF03776 Septum formation topological specificity factor MinE 14 81 7.1E-27 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CVS48_RS01490 0c57a4d7c77fa007ff218ff9a36ce41d 85 Gene3D G3DSA:3.30.1070.10 1 82 7.1E-30 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CVS48_RS04485 3bc70f3b71ed42ec2fca6b5de0a19c97 96 Pfam PF02583 Metal-sensitive transcriptional repressor 7 92 1.2E-18 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CVS48_RS25955 ce49bf52a445084f13456855527342d2 625 Pfam PF02653 Branched-chain amino acid transport system / permease component 349 605 3.1E-30 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS25955 ce49bf52a445084f13456855527342d2 625 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 290 3.4E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS25955 ce49bf52a445084f13456855527342d2 625 Gene3D G3DSA:1.10.3470.10 1 295 1.3E-42 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS25955 ce49bf52a445084f13456855527342d2 625 Gene3D G3DSA:1.10.3470.10 334 610 8.4E-31 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS17105 7faee73e0f7237a7942f92f1b9cb225c 237 Pfam PF01914 MarC family integral membrane protein 14 220 1.9E-35 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CVS48_RS17105 7faee73e0f7237a7942f92f1b9cb225c 237 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 14 216 5.8E-33 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CVS48_RS21805 9533e38e37bb6ba05a925b38d367064c 566 Pfam PF01368 DHH family 77 205 1.5E-8 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS21805 9533e38e37bb6ba05a925b38d367064c 566 Pfam PF02272 DHHA1 domain 324 452 5.9E-20 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CVS48_RS21805 9533e38e37bb6ba05a925b38d367064c 566 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 25 564 2.6E-136 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CVS48_RS21805 9533e38e37bb6ba05a925b38d367064c 566 SUPERFAMILY SSF64182 50 464 9.16E-111 T 29-03-2018 CVS48_RS21805 9533e38e37bb6ba05a925b38d367064c 566 Gene3D G3DSA:3.90.1640.10 56 249 7.9E-21 T 29-03-2018 CVS48_RS27700 d2789c8465517325bbe019172cf460a8 716 Pfam PF06733 DEAD_2 177 253 1.5E-4 T 29-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 CVS48_RS27700 d2789c8465517325bbe019172cf460a8 716 SUPERFAMILY SSF52540 191 248 4.44E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27700 d2789c8465517325bbe019172cf460a8 716 SUPERFAMILY SSF52540 639 666 4.44E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27700 d2789c8465517325bbe019172cf460a8 716 SUPERFAMILY SSF52540 3 113 4.44E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27700 d2789c8465517325bbe019172cf460a8 716 SUPERFAMILY SSF52540 535 667 7.17E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27700 d2789c8465517325bbe019172cf460a8 716 Pfam PF13307 Helicase C-terminal domain 530 693 5.9E-33 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CVS48_RS27700 d2789c8465517325bbe019172cf460a8 716 Gene3D G3DSA:3.40.50.300 23 490 5.0E-27 T 29-03-2018 CVS48_RS27700 d2789c8465517325bbe019172cf460a8 716 Gene3D G3DSA:3.40.50.300 521 692 1.0E-10 T 29-03-2018 CVS48_RS27700 d2789c8465517325bbe019172cf460a8 716 SMART SM00491 554 680 1.8E-28 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CVS48_RS06535 f52ffd37dba3f22470c5b4698b60e233 146 Gene3D G3DSA:3.100.10.10 45 146 9.7E-24 T 29-03-2018 CVS48_RS06535 f52ffd37dba3f22470c5b4698b60e233 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 6 146 19.63 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CVS48_RS06535 f52ffd37dba3f22470c5b4698b60e233 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 145 4.5E-47 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06535 f52ffd37dba3f22470c5b4698b60e233 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 31 145 8.1E-29 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CVS48_RS06535 f52ffd37dba3f22470c5b4698b60e233 146 SUPERFAMILY SSF52080 7 144 2.22E-45 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CVS48_RS04730 23551bf99c92ff817e5ec70fb3305b2c 829 SUPERFAMILY SSF48452 756 805 3.37E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04730 23551bf99c92ff817e5ec70fb3305b2c 829 SUPERFAMILY SSF48452 538 684 3.37E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04730 23551bf99c92ff817e5ec70fb3305b2c 829 Gene3D G3DSA:1.25.40.10 756 829 0.059 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04730 23551bf99c92ff817e5ec70fb3305b2c 829 Gene3D G3DSA:3.40.50.1110 46 271 4.8E-4 T 29-03-2018 CVS48_RS04730 23551bf99c92ff817e5ec70fb3305b2c 829 Gene3D G3DSA:1.25.40.10 374 544 0.0045 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04730 23551bf99c92ff817e5ec70fb3305b2c 829 Gene3D G3DSA:1.25.40.10 545 738 1.4E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04730 23551bf99c92ff817e5ec70fb3305b2c 829 Gene3D G3DSA:1.25.40.10 272 373 3.5E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS22320 1bb5581d64c986d094d719291fcf2234 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 281 8.3E-41 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS22320 1bb5581d64c986d094d719291fcf2234 303 SMART SM00062 51 287 2.1E-39 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS22320 1bb5581d64c986d094d719291fcf2234 303 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 36 300 1.8E-94 T 29-03-2018 IPR014337 Ectoine/Hydroxyectoine ABC transporter, substrate-binding protein EhuB GO:0033294|GO:0051470 CVS48_RS22320 1bb5581d64c986d094d719291fcf2234 303 SUPERFAMILY SSF53850 47 283 7.47E-40 T 29-03-2018 CVS48_RS22320 1bb5581d64c986d094d719291fcf2234 303 Gene3D G3DSA:3.40.190.10 41 152 8.9E-26 T 29-03-2018 CVS48_RS22320 1bb5581d64c986d094d719291fcf2234 303 Gene3D G3DSA:3.40.190.10 153 239 4.1E-12 T 29-03-2018 CVS48_RS06460 491a5af6eb714fee5b7f3da6a86f4173 256 Gene3D G3DSA:3.40.50.300 1 255 2.2E-55 T 29-03-2018 CVS48_RS06460 491a5af6eb714fee5b7f3da6a86f4173 256 SUPERFAMILY SSF52540 2 247 1.85E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06460 491a5af6eb714fee5b7f3da6a86f4173 256 Pfam PF00005 ABC transporter 18 177 1.3E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS06460 491a5af6eb714fee5b7f3da6a86f4173 256 SMART SM00382 26 226 6.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS00570 a9d016e57723104e11c106cbeca7bb4b 100 SUPERFAMILY SSF46785 3 97 1.84E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00570 a9d016e57723104e11c106cbeca7bb4b 100 Gene3D G3DSA:1.10.10.10 1 95 6.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00570 a9d016e57723104e11c106cbeca7bb4b 100 Pfam PF03551 Transcriptional regulator PadR-like family 15 83 1.7E-20 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 Pfam PF13599 Pentapeptide repeats (9 copies) 630 696 2.7E-10 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 SUPERFAMILY SSF141571 570 736 5.33E-34 T 29-03-2018 CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 Gene3D G3DSA:2.160.10.20 791 875 8.2E-15 T 29-03-2018 CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 Gene3D G3DSA:2.160.10.20 661 751 1.2E-15 T 29-03-2018 CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 Gene3D G3DSA:2.160.10.20 557 660 1.3E-23 T 29-03-2018 CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 SUPERFAMILY SSF141571 752 872 9.61E-22 T 29-03-2018 CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 Gene3D G3DSA:3.30.1120.50 752 790 3.2E-6 T 29-03-2018 CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 40 295 4.1E-63 T 29-03-2018 IPR018683 Domain of unknown function DUF2169 CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 Pfam PF00805 Pentapeptide repeats (8 copies) 752 787 9.2E-6 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 Pfam PF00805 Pentapeptide repeats (8 copies) 810 847 1.3E-6 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS08525 43f8e631bc2acdee6a23b2607b414edc 879 Pfam PF00805 Pentapeptide repeats (8 copies) 569 608 3.8E-7 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS24710 4989d253fd5874be0a218d0a8191f538 221 Gene3D G3DSA:3.40.630.30 20 189 3.4E-4 T 29-03-2018 CVS48_RS07400 bdffe982d67af72c6c9c3b0569615424 78 Pfam PF06945 Protein of unknown function (DUF1289) 26 70 1.4E-17 T 29-03-2018 IPR010710 Protein of unknown function DUF1289 CVS48_RS27170 e7972166ecd3df2b233f23076f360f5e 167 SUPERFAMILY SSF74942 75 118 1.07E-9 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CVS48_RS27170 e7972166ecd3df2b233f23076f360f5e 167 Pfam PF17384 RimP C-terminal SH3 domain 77 158 5.2E-9 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CVS48_RS27170 e7972166ecd3df2b233f23076f360f5e 167 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 2 160 21.055 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CVS48_RS27170 e7972166ecd3df2b233f23076f360f5e 167 Pfam PF02576 RimP N-terminal domain 9 74 4.0E-16 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CVS48_RS27170 e7972166ecd3df2b233f23076f360f5e 167 Gene3D G3DSA:2.30.30.180 78 157 1.6E-16 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CVS48_RS27170 e7972166ecd3df2b233f23076f360f5e 167 Gene3D G3DSA:3.30.300.70 2 71 2.7E-18 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CVS48_RS27170 e7972166ecd3df2b233f23076f360f5e 167 SUPERFAMILY SSF75420 3 74 4.58E-15 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CVS48_RS03595 57db725d34b39915a2ad3b0581230063 484 SUPERFAMILY SSF103473 260 467 2.22E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS03595 57db725d34b39915a2ad3b0581230063 484 SUPERFAMILY SSF103473 15 209 2.22E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS03595 57db725d34b39915a2ad3b0581230063 484 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 32 434 5.2E-73 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CVS48_RS03595 57db725d34b39915a2ad3b0581230063 484 Pfam PF07690 Major Facilitator Superfamily 31 301 9.0E-34 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS03595 57db725d34b39915a2ad3b0581230063 484 Gene3D G3DSA:1.20.1250.20 271 483 4.4E-21 T 29-03-2018 CVS48_RS03595 57db725d34b39915a2ad3b0581230063 484 Gene3D G3DSA:1.20.1250.20 19 212 3.5E-30 T 29-03-2018 CVS48_RS26000 020ec5be327a780a3304607716010174 220 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 16 175 23.986 T 29-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 CVS48_RS26000 020ec5be327a780a3304607716010174 220 Pfam PF04390 Lipopolysaccharide-assembly 44 170 1.8E-8 T 29-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 CVS48_RS26000 020ec5be327a780a3304607716010174 220 Gene3D G3DSA:3.30.160.150 31 185 4.6E-41 T 29-03-2018 CVS48_RS26505 090f727845c45e9b9437a3110ca05cea 325 SUPERFAMILY SSF53335 260 320 5.12E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS26505 090f727845c45e9b9437a3110ca05cea 325 SUPERFAMILY SSF53335 74 213 5.12E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS26505 090f727845c45e9b9437a3110ca05cea 325 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 28 324 3.2E-97 T 29-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent CVS48_RS26505 090f727845c45e9b9437a3110ca05cea 325 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 27 321 4.9E-112 T 29-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 CVS48_RS26505 090f727845c45e9b9437a3110ca05cea 325 Gene3D G3DSA:3.40.50.150 11 325 6.5E-22 T 29-03-2018 CVS48_RS26505 090f727845c45e9b9437a3110ca05cea 325 PIRSF PIRSF018005 3 325 1.7E-104 T 29-03-2018 IPR017804 Methyltransferase EgtD-like CVS48_RS11575 a545effaf961767864829a0c7d9ca0b0 324 PIRSF PIRSF017082 1 324 1.4E-79 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11575 a545effaf961767864829a0c7d9ca0b0 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 1.3E-75 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11575 a545effaf961767864829a0c7d9ca0b0 324 SUPERFAMILY SSF53850 93 275 1.77E-11 T 29-03-2018 CVS48_RS11575 a545effaf961767864829a0c7d9ca0b0 324 Gene3D G3DSA:3.40.190.10 124 297 7.6E-10 T 29-03-2018 CVS48_RS05405 8b1c7a23cf9c935355bddea1e143e04d 442 Pfam PF01425 Amidase 27 415 2.8E-87 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS05405 8b1c7a23cf9c935355bddea1e143e04d 442 SUPERFAMILY SSF75304 5 423 1.31E-118 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS05405 8b1c7a23cf9c935355bddea1e143e04d 442 Gene3D G3DSA:3.90.1300.10 1 434 7.0E-119 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS02965 15b31881def8693cfc3f7adf967a3ce0 159 Pfam PF03477 ATP cone domain 50 136 3.4E-15 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CVS48_RS02965 15b31881def8693cfc3f7adf967a3ce0 159 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 85.763 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CVS48_RS02965 15b31881def8693cfc3f7adf967a3ce0 159 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 1.7E-60 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CVS48_RS01355 60fac6756c661c8f176ee8e396417d8c 453 Gene3D G3DSA:1.25.40.10 103 449 6.0E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS01355 60fac6756c661c8f176ee8e396417d8c 453 SUPERFAMILY SSF48452 271 424 9.49E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS01355 60fac6756c661c8f176ee8e396417d8c 453 Gene3D G3DSA:3.30.2010.10 13 102 1.8E-20 T 29-03-2018 CVS48_RS01355 60fac6756c661c8f176ee8e396417d8c 453 Pfam PF01435 Peptidase family M48 27 217 6.5E-34 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 148 3.2E-66 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 Gene3D G3DSA:3.90.226.10 23 317 2.8E-69 T 29-03-2018 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 317 8.3E-148 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 SUPERFAMILY SSF52096 5 316 1.1E-101 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 50.001 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 4.5E-46 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 4.5E-46 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 4.5E-46 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 4.5E-46 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 4.5E-46 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS24045 623fddd2b71e61706339af69a47a80f6 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 4.5E-46 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 PIRSF PIRSF000018 1 437 2.2E-162 T 29-03-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 SUPERFAMILY SSF46626 185 295 3.78E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 Gene3D G3DSA:1.10.760.10 317 437 1.8E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 Pfam PF00034 Cytochrome c 35 132 1.6E-5 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 Pfam PF00034 Cytochrome c 326 410 1.8E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 Gene3D G3DSA:1.10.760.10 162 316 1.7E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 SUPERFAMILY SSF46626 25 155 5.58E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 Gene3D G3DSA:1.10.760.10 3 147 4.2E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 PRINTS PR00605 Class IC cytochrome C signature 385 407 1.0E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 PRINTS PR00605 Class IC cytochrome C signature 332 343 1.0E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CVS48_RS20730 1ad00188a74e62e64d2db719ca043c92 438 SUPERFAMILY SSF46626 325 428 9.6E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS02535 a1a69bbab4b923a5b0ad00145a6971e3 92 SMART SM00151 17 92 9.5E-35 T 29-03-2018 IPR019835 SWIB domain Reactome: R-HSA-3214858 CVS48_RS02535 a1a69bbab4b923a5b0ad00145a6971e3 92 Gene3D G3DSA:1.10.245.10 1 92 3.5E-30 T 29-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 CVS48_RS02535 a1a69bbab4b923a5b0ad00145a6971e3 92 SUPERFAMILY SSF47592 12 91 2.62E-28 T 29-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 CVS48_RS02535 a1a69bbab4b923a5b0ad00145a6971e3 92 Pfam PF02201 SWIB/MDM2 domain 19 91 1.3E-29 T 29-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 CVS48_RS13255 c69bd36c2c7543423ccd248698c3b4d6 327 SUPERFAMILY SSF53850 48 240 5.6E-37 T 29-03-2018 CVS48_RS13255 c69bd36c2c7543423ccd248698c3b4d6 327 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 29 277 9.5E-62 T 29-03-2018 CVS48_RS13255 c69bd36c2c7543423ccd248698c3b4d6 327 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 8 250 1.2E-75 T 29-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CVS48_RS13255 c69bd36c2c7543423ccd248698c3b4d6 327 Gene3D G3DSA:3.40.190.10 19 126 1.1E-6 T 29-03-2018 CVS48_RS13255 c69bd36c2c7543423ccd248698c3b4d6 327 Gene3D G3DSA:3.40.190.10 127 275 1.3E-21 T 29-03-2018 CVS48_RS13255 c69bd36c2c7543423ccd248698c3b4d6 327 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 1 290 3.4E-106 T 29-03-2018 IPR017797 Phosphonate ABC transporter, substrate-binding protein GO:0015716|GO:0043190 CVS48_RS28385 2d915be13be017525b96f5294d23f95e 182 PIRSF PIRSF029681 1 182 1.8E-52 T 29-03-2018 IPR018550 Lipid A 3-O-deacylase-related CVS48_RS28385 2d915be13be017525b96f5294d23f95e 182 SUPERFAMILY SSF56925 20 182 1.07E-11 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CVS48_RS28385 2d915be13be017525b96f5294d23f95e 182 Gene3D G3DSA:2.40.160.20 32 182 4.7E-34 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CVS48_RS28385 2d915be13be017525b96f5294d23f95e 182 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 48 180 2.9E-32 T 29-03-2018 IPR018550 Lipid A 3-O-deacylase-related CVS48_RS22500 1523152bd9e2e36415c18129417d85cd 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.376 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS22500 1523152bd9e2e36415c18129417d85cd 87 SUPERFAMILY SSF46992 3 86 1.44E-29 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS22500 1523152bd9e2e36415c18129417d85cd 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 2.0E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS22500 1523152bd9e2e36415c18129417d85cd 87 Pfam PF01649 Ribosomal protein S20 2 84 1.7E-25 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS22500 1523152bd9e2e36415c18129417d85cd 87 Gene3D G3DSA:1.20.58.110 1 87 7.4E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS22500 1523152bd9e2e36415c18129417d85cd 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 1.0E-30 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS01320 54a919ba653853667e6ed467b89381de 127 SUPERFAMILY SSF52833 22 105 2.39E-15 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS01320 54a919ba653853667e6ed467b89381de 127 Gene3D G3DSA:3.40.30.10 25 117 8.5E-13 T 29-03-2018 CVS48_RS01320 54a919ba653853667e6ed467b89381de 127 Pfam PF00085 Thioredoxin 25 81 1.9E-9 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CVS48_RS19410 b533a4debd1f0949d47d6f20a2dfcf36 128 SUPERFAMILY SSF55298 1 128 2.83E-40 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS19410 b533a4debd1f0949d47d6f20a2dfcf36 128 Pfam PF01042 Endoribonuclease L-PSP 9 127 5.8E-38 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS19410 b533a4debd1f0949d47d6f20a2dfcf36 128 Gene3D G3DSA:3.30.1330.40 1 128 8.5E-42 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS19410 b533a4debd1f0949d47d6f20a2dfcf36 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 127 1.8E-43 T 29-03-2018 IPR006056 RidA family CVS48_RS17995 edd4e1b693c13288a517950c636a52cf 390 PIRSF PIRSF000429 13 376 2.0E-12 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS17995 edd4e1b693c13288a517950c636a52cf 390 SUPERFAMILY SSF53901 264 372 3.45E-15 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS17995 edd4e1b693c13288a517950c636a52cf 390 Gene3D G3DSA:3.40.47.10 225 386 1.0E-6 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS17995 edd4e1b693c13288a517950c636a52cf 390 Gene3D G3DSA:3.40.47.10 6 224 1.7E-12 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS17995 edd4e1b693c13288a517950c636a52cf 390 SUPERFAMILY SSF53901 190 387 4.8E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS17995 edd4e1b693c13288a517950c636a52cf 390 SUPERFAMILY SSF53901 35 128 4.8E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15690 82ff7f5dcbb579085cec6914cf5047cc 256 SUPERFAMILY SSF54862 54 234 1.88E-66 T 29-03-2018 CVS48_RS15690 82ff7f5dcbb579085cec6914cf5047cc 256 Pfam PF13247 4Fe-4S dicluster domain 105 199 2.5E-29 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS15690 82ff7f5dcbb579085cec6914cf5047cc 256 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS15690 82ff7f5dcbb579085cec6914cf5047cc 256 Gene3D G3DSA:3.30.70.20 29 67 0.0035 T 29-03-2018 CVS48_RS15690 82ff7f5dcbb579085cec6914cf5047cc 256 Gene3D G3DSA:3.30.70.20 126 165 3.0E-20 T 29-03-2018 CVS48_RS15690 82ff7f5dcbb579085cec6914cf5047cc 256 Gene3D G3DSA:3.30.70.20 166 244 1.1E-24 T 29-03-2018 CVS48_RS15690 82ff7f5dcbb579085cec6914cf5047cc 256 Gene3D G3DSA:3.30.70.20 68 125 2.0E-17 T 29-03-2018 CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 Gene3D G3DSA:3.40.50.1100 156 331 5.5E-44 T 29-03-2018 CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 SUPERFAMILY SSF55021 345 430 2.98E-24 T 29-03-2018 CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 20 520 2.2E-231 T 29-03-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 Gene3D G3DSA:3.40.50.1100 42 155 1.3E-31 T 29-03-2018 CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 338 426 3.3E-25 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 438 520 2.6E-20 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 33 324 4.7E-74 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 SUPERFAMILY SSF55021 427 520 7.1E-24 T 29-03-2018 CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 Gene3D G3DSA:3.40.1020.10 346 521 2.7E-71 T 29-03-2018 CVS48_RS18035 d9753b1ffe12119a7ab89940c02c5cfb 521 SUPERFAMILY SSF53686 16 373 5.89E-92 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS11215 376ba02e8a40805044205372574062ee 291 SUPERFAMILY SSF54637 9 158 1.13E-36 T 29-03-2018 IPR029069 HotDog domain CVS48_RS11215 376ba02e8a40805044205372574062ee 291 SUPERFAMILY SSF54637 163 278 1.79E-27 T 29-03-2018 IPR029069 HotDog domain CVS48_RS11215 376ba02e8a40805044205372574062ee 291 Pfam PF13452 N-terminal half of MaoC dehydratase 50 137 4.1E-9 T 29-03-2018 CVS48_RS11215 376ba02e8a40805044205372574062ee 291 Gene3D G3DSA:3.10.129.10 163 291 5.1E-23 T 29-03-2018 CVS48_RS11215 376ba02e8a40805044205372574062ee 291 Gene3D G3DSA:3.10.129.10 12 162 4.6E-32 T 29-03-2018 CVS48_RS11215 376ba02e8a40805044205372574062ee 291 Pfam PF01575 MaoC like domain 162 271 3.6E-25 T 29-03-2018 IPR002539 MaoC-like domain CVS48_RS18490 2e26c6f752880af37ab1f5b6d51e746a 205 Gene3D G3DSA:1.10.357.10 71 205 2.3E-16 T 29-03-2018 CVS48_RS18490 2e26c6f752880af37ab1f5b6d51e746a 205 Gene3D G3DSA:1.10.10.60 1 70 1.3E-15 T 29-03-2018 CVS48_RS18490 2e26c6f752880af37ab1f5b6d51e746a 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 65 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CVS48_RS18490 2e26c6f752880af37ab1f5b6d51e746a 205 SUPERFAMILY SSF46689 13 94 4.31E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS18490 2e26c6f752880af37ab1f5b6d51e746a 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 5.7E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS18490 2e26c6f752880af37ab1f5b6d51e746a 205 SUPERFAMILY SSF48498 90 204 2.99E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS18490 2e26c6f752880af37ab1f5b6d51e746a 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS18490 2e26c6f752880af37ab1f5b6d51e746a 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS04225 5d5273cbc85f83912691279f45a530b8 242 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 45 59 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CVS48_RS04225 5d5273cbc85f83912691279f45a530b8 242 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 18 231 2.9E-93 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CVS48_RS04225 5d5273cbc85f83912691279f45a530b8 242 Pfam PF00834 Ribulose-phosphate 3 epimerase family 18 218 5.0E-86 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CVS48_RS04225 5d5273cbc85f83912691279f45a530b8 242 Gene3D G3DSA:3.20.20.70 6 235 1.6E-83 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS04225 5d5273cbc85f83912691279f45a530b8 242 PIRSF PIRSF001461 12 241 3.3E-100 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CVS48_RS04225 5d5273cbc85f83912691279f45a530b8 242 SUPERFAMILY SSF51366 8 232 2.77E-72 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CVS48_RS04225 5d5273cbc85f83912691279f45a530b8 242 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 147 169 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 Gene3D G3DSA:3.30.930.10 105 448 2.2E-89 T 29-03-2018 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 445 38.593 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 PIRSF PIRSF001529 1 448 2.6E-164 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 248 423 7.8E-35 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 440 1.9E-151 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 PRINTS PR00981 Seryl-tRNA synthetase signature 300 313 2.8E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 PRINTS PR00981 Seryl-tRNA synthetase signature 288 300 2.8E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 PRINTS PR00981 Seryl-tRNA synthetase signature 357 373 2.8E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 PRINTS PR00981 Seryl-tRNA synthetase signature 340 353 2.8E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 PRINTS PR00981 Seryl-tRNA synthetase signature 375 391 2.8E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 5.3E-28 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 SUPERFAMILY SSF46589 1 112 6.8E-29 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 SUPERFAMILY SSF55681 136 442 5.24E-95 T 29-03-2018 CVS48_RS00190 41819532b6081c2406a5bb0aaf67dbf9 448 Gene3D G3DSA:1.10.287.40 2 104 2.7E-23 T 29-03-2018 CVS48_RS25120 312165166d8242b6758d1a8d29e555be 459 Gene3D G3DSA:2.30.40.10 39 106 2.5E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25120 312165166d8242b6758d1a8d29e555be 459 SUPERFAMILY SSF51556 94 400 2.72E-76 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS25120 312165166d8242b6758d1a8d29e555be 459 Gene3D G3DSA:2.30.40.10 384 454 2.9E-4 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25120 312165166d8242b6758d1a8d29e555be 459 Gene3D G3DSA:3.20.20.140 107 383 1.7E-39 T 29-03-2018 CVS48_RS25120 312165166d8242b6758d1a8d29e555be 459 SUPERFAMILY SSF51338 409 429 2.39E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25120 312165166d8242b6758d1a8d29e555be 459 SUPERFAMILY SSF51338 40 93 2.39E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25120 312165166d8242b6758d1a8d29e555be 459 Pfam PF01979 Amidohydrolase family 90 449 2.0E-33 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS25120 312165166d8242b6758d1a8d29e555be 459 SUPERFAMILY SSF51338 411 454 5.4E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS09970 70ce3194730e5cd366dea762b5f2eea8 404 Gene3D G3DSA:3.40.50.2300 163 333 1.1E-31 T 29-03-2018 CVS48_RS09970 70ce3194730e5cd366dea762b5f2eea8 404 Gene3D G3DSA:3.40.50.2300 32 162 1.9E-10 T 29-03-2018 CVS48_RS09970 70ce3194730e5cd366dea762b5f2eea8 404 Pfam PF13458 Periplasmic binding protein 33 368 4.5E-85 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS09970 70ce3194730e5cd366dea762b5f2eea8 404 SUPERFAMILY SSF53822 33 402 4.12E-85 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS01285 01c365602c71577e9f67ab3d7ef6efd7 244 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 110 231 8.8E-39 T 29-03-2018 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 CVS48_RS01285 01c365602c71577e9f67ab3d7ef6efd7 244 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 3 240 45.303 T 29-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 CVS48_RS01285 01c365602c71577e9f67ab3d7ef6efd7 244 PIRSF PIRSF037208 3 243 7.9E-89 T 29-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 CVS48_RS01285 01c365602c71577e9f67ab3d7ef6efd7 244 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 20 90 1.6E-19 T 29-03-2018 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 CVS48_RS01285 01c365602c71577e9f67ab3d7ef6efd7 244 SUPERFAMILY SSF55729 84 242 2.54E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS13090 71f9ba76dbf61b43f1f95d445dedbda7 272 Gene3D G3DSA:1.10.530.10 95 263 4.9E-23 T 29-03-2018 CVS48_RS13090 71f9ba76dbf61b43f1f95d445dedbda7 272 SUPERFAMILY SSF53955 140 256 2.08E-23 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS13090 71f9ba76dbf61b43f1f95d445dedbda7 272 Pfam PF01464 Transglycosylase SLT domain 156 241 1.1E-13 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CVS48_RS07760 dd5198e6b4e8d94731d8eedbad72f9b9 206 Pfam PF03968 OstA-like protein 45 162 2.8E-23 T 29-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal CVS48_RS07760 dd5198e6b4e8d94731d8eedbad72f9b9 206 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 44 185 2.9E-27 T 29-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 CVS48_RS07760 dd5198e6b4e8d94731d8eedbad72f9b9 206 Gene3D G3DSA:2.60.450.10 34 183 2.3E-21 T 29-03-2018 CVS48_RS07760 dd5198e6b4e8d94731d8eedbad72f9b9 206 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 13 186 22.003 T 29-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 CVS48_RS27455 bb7a646d84ca80bb41cdc53879e71df3 194 Gene3D G3DSA:1.10.150.280 33 122 1.2E-16 T 29-03-2018 CVS48_RS27455 bb7a646d84ca80bb41cdc53879e71df3 194 Gene3D G3DSA:1.10.150.20 123 156 0.059 T 29-03-2018 CVS48_RS27455 bb7a646d84ca80bb41cdc53879e71df3 194 Pfam PF12836 Helix-hairpin-helix motif 77 133 4.7E-14 T 29-03-2018 CVS48_RS27455 bb7a646d84ca80bb41cdc53879e71df3 194 SMART SM00278 86 105 10.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS27455 bb7a646d84ca80bb41cdc53879e71df3 194 SMART SM00278 117 136 4.7 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CVS48_RS27455 bb7a646d84ca80bb41cdc53879e71df3 194 SUPERFAMILY SSF47781 77 134 1.78E-16 T 29-03-2018 IPR010994 RuvA domain 2-like CVS48_RS03335 d4608d80a7946ea466033d1d2e351874 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 29-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CVS48_RS03335 d4608d80a7946ea466033d1d2e351874 54 Pfam PF00301 Rubredoxin 4 49 6.5E-23 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 CVS48_RS03335 d4608d80a7946ea466033d1d2e351874 54 PRINTS PR00163 Rubredoxin signature 3 19 3.4E-8 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 CVS48_RS03335 d4608d80a7946ea466033d1d2e351874 54 PRINTS PR00163 Rubredoxin signature 33 49 3.4E-8 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 CVS48_RS03335 d4608d80a7946ea466033d1d2e351874 54 SUPERFAMILY SSF57802 1 53 3.2E-23 T 29-03-2018 CVS48_RS03335 d4608d80a7946ea466033d1d2e351874 54 Gene3D G3DSA:2.20.28.10 1 53 5.5E-25 T 29-03-2018 CVS48_RS03335 d4608d80a7946ea466033d1d2e351874 54 PIRSF PIRSF000071 1 54 4.1E-26 T 29-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 CVS48_RS03125 45447a600c70357f988fbf90504dee07 250 Pfam PF07382 Histone H1-like nucleoprotein HC2 2 135 5.5E-21 T 29-03-2018 IPR009970 Histone H1-like nucleoprotein HC2 GO:0003677|GO:0030261 CVS48_RS03125 45447a600c70357f988fbf90504dee07 250 Pfam PF07382 Histone H1-like nucleoprotein HC2 131 249 5.1E-18 T 29-03-2018 IPR009970 Histone H1-like nucleoprotein HC2 GO:0003677|GO:0030261 CVS48_RS03125 45447a600c70357f988fbf90504dee07 250 PRINTS PR00624 Histone H5 signature 43 64 1.1E-5 T 29-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 CVS48_RS03125 45447a600c70357f988fbf90504dee07 250 PRINTS PR00624 Histone H5 signature 200 219 1.1E-5 T 29-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 CVS48_RS03125 45447a600c70357f988fbf90504dee07 250 PRINTS PR00624 Histone H5 signature 146 160 1.1E-5 T 29-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 CVS48_RS03125 45447a600c70357f988fbf90504dee07 250 PRINTS PR00624 Histone H5 signature 178 195 1.1E-5 T 29-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 CVS48_RS13730 af67e8ba6519264d7d7313e056595ffe 108 SUPERFAMILY SSF82607 10 102 2.22E-34 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CVS48_RS13730 af67e8ba6519264d7d7313e056595ffe 108 Gene3D G3DSA:3.30.1310.10 1 108 5.2E-42 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CVS48_RS13730 af67e8ba6519264d7d7313e056595ffe 108 Pfam PF02575 YbaB/EbfC DNA-binding family 10 98 1.6E-34 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CVS48_RS13730 af67e8ba6519264d7d7313e056595ffe 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 7.0E-32 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CVS48_RS13730 af67e8ba6519264d7d7313e056595ffe 108 PIRSF PIRSF004555 2 108 5.8E-37 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CVS48_RS13730 af67e8ba6519264d7d7313e056595ffe 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 97 22.445 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CVS48_RS11245 65b872bb37dbec8d60a2fdf9b3bc024b 312 SUPERFAMILY SSF53850 86 276 7.96E-10 T 29-03-2018 CVS48_RS11245 65b872bb37dbec8d60a2fdf9b3bc024b 312 PIRSF PIRSF017082 1 312 4.5E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11245 65b872bb37dbec8d60a2fdf9b3bc024b 312 Gene3D G3DSA:3.40.190.10 114 223 1.2E-8 T 29-03-2018 CVS48_RS11245 65b872bb37dbec8d60a2fdf9b3bc024b 312 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 39 308 1.9E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS16655 a6c7c7e98cc2fbce2b271d20708bac99 261 Gene3D G3DSA:3.40.50.150 8 52 0.04 T 29-03-2018 CVS48_RS16655 a6c7c7e98cc2fbce2b271d20708bac99 261 Pfam PF13489 Methyltransferase domain 21 152 2.3E-7 T 29-03-2018 CVS48_RS16655 a6c7c7e98cc2fbce2b271d20708bac99 261 SUPERFAMILY SSF53335 10 222 3.51E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS16655 a6c7c7e98cc2fbce2b271d20708bac99 261 Gene3D G3DSA:3.40.50.150 78 238 2.6E-14 T 29-03-2018 CVS48_RS09160 18d7fd857271494cde40f597c30ea5c5 202 SUPERFAMILY SSF47616 73 201 5.01E-16 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS09160 18d7fd857271494cde40f597c30ea5c5 202 Gene3D G3DSA:3.40.30.10 1 91 7.4E-16 T 29-03-2018 CVS48_RS09160 18d7fd857271494cde40f597c30ea5c5 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 77 6.8E-16 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS09160 18d7fd857271494cde40f597c30ea5c5 202 SUPERFAMILY SSF52833 1 77 2.38E-15 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS09160 18d7fd857271494cde40f597c30ea5c5 202 Gene3D G3DSA:1.20.1050.10 92 202 5.6E-12 T 29-03-2018 CVS48_RS10120 c23b1a631b21181bc055c2033f91c183 154 Pfam PF03061 Thioesterase superfamily 64 137 1.9E-13 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CVS48_RS10120 c23b1a631b21181bc055c2033f91c183 154 Gene3D G3DSA:3.10.129.10 45 148 1.2E-22 T 29-03-2018 CVS48_RS10120 c23b1a631b21181bc055c2033f91c183 154 SUPERFAMILY SSF54637 53 144 7.63E-24 T 29-03-2018 IPR029069 HotDog domain CVS48_RS05225 1e65e4dd55c82a9b04f4549bd55d9a2a 261 SUPERFAMILY SSF52540 4 233 1.87E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05225 1e65e4dd55c82a9b04f4549bd55d9a2a 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05225 1e65e4dd55c82a9b04f4549bd55d9a2a 261 Pfam PF00005 ABC transporter 21 176 4.3E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05225 1e65e4dd55c82a9b04f4549bd55d9a2a 261 Gene3D G3DSA:3.40.50.300 2 240 3.2E-51 T 29-03-2018 CVS48_RS05225 1e65e4dd55c82a9b04f4549bd55d9a2a 261 SMART SM00382 30 232 1.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS00360 cbf6829a1909e789781b196937567a5e 120 Gene3D G3DSA:1.10.760.10 7 112 5.4E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS00360 cbf6829a1909e789781b196937567a5e 120 Pfam PF00034 Cytochrome c 26 112 5.3E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS00360 cbf6829a1909e789781b196937567a5e 120 SUPERFAMILY SSF46626 4 114 1.29E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS00360 cbf6829a1909e789781b196937567a5e 120 PRINTS PR00605 Class IC cytochrome C signature 35 46 6.0E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CVS48_RS00360 cbf6829a1909e789781b196937567a5e 120 PRINTS PR00605 Class IC cytochrome C signature 87 109 6.0E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CVS48_RS25335 9c8d2d642216af568726446371dad9db 430 SUPERFAMILY SSF56931 188 429 2.35E-55 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CVS48_RS25335 9c8d2d642216af568726446371dad9db 430 Gene3D G3DSA:2.40.230.10 185 430 3.1E-53 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CVS48_RS25335 9c8d2d642216af568726446371dad9db 430 Pfam PF02253 Phospholipase A1 212 428 2.2E-35 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CVS48_RS25335 9c8d2d642216af568726446371dad9db 430 PRINTS PR01486 Bacterial phospholipase A1 protein signature 210 227 1.3E-9 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CVS48_RS25335 9c8d2d642216af568726446371dad9db 430 PRINTS PR01486 Bacterial phospholipase A1 protein signature 340 358 1.3E-9 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CVS48_RS25335 9c8d2d642216af568726446371dad9db 430 PRINTS PR01486 Bacterial phospholipase A1 protein signature 288 302 1.3E-9 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CVS48_RS25335 9c8d2d642216af568726446371dad9db 430 PRINTS PR01486 Bacterial phospholipase A1 protein signature 400 420 1.3E-9 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CVS48_RS09445 6eb9c77ee8a1d3ca88cc707d8bdf7949 399 Gene3D G3DSA:2.40.50.100 71 143 8.6E-19 T 29-03-2018 CVS48_RS09445 6eb9c77ee8a1d3ca88cc707d8bdf7949 399 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 378 5.8E-87 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS09445 6eb9c77ee8a1d3ca88cc707d8bdf7949 399 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 297 1.9E-15 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS09445 6eb9c77ee8a1d3ca88cc707d8bdf7949 399 SUPERFAMILY SSF111369 62 301 4.18E-64 T 29-03-2018 CVS48_RS09445 6eb9c77ee8a1d3ca88cc707d8bdf7949 399 Gene3D G3DSA:2.40.50.100 171 380 5.9E-6 T 29-03-2018 CVS48_RS13600 19cf8748c80597692075381d65631820 648 ProSitePatterns PS00211 ABC transporters family signature. 517 531 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13600 19cf8748c80597692075381d65631820 648 SUPERFAMILY SSF52540 486 623 8.98E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13600 19cf8748c80597692075381d65631820 648 SUPERFAMILY SSF52540 341 455 8.98E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13600 19cf8748c80597692075381d65631820 648 Gene3D G3DSA:3.40.50.300 1 323 1.9E-67 T 29-03-2018 CVS48_RS13600 19cf8748c80597692075381d65631820 648 Gene3D G3DSA:3.40.50.300 349 647 1.5E-62 T 29-03-2018 CVS48_RS13600 19cf8748c80597692075381d65631820 648 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 321 1.4E-15 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS13600 19cf8748c80597692075381d65631820 648 SUPERFAMILY SSF52540 4 256 7.61E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13600 19cf8748c80597692075381d65631820 648 Pfam PF00005 ABC transporter 378 543 4.8E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13600 19cf8748c80597692075381d65631820 648 Pfam PF00005 ABC transporter 27 184 1.0E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13600 19cf8748c80597692075381d65631820 648 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 596 628 5.2E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS13600 19cf8748c80597692075381d65631820 648 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 302 6.9E-15 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS13600 19cf8748c80597692075381d65631820 648 SMART SM00382 387 593 4.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13600 19cf8748c80597692075381d65631820 648 SMART SM00382 36 242 1.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13600 19cf8748c80597692075381d65631820 648 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS01635 3592d49ea658457373f7a1e5b93f34cb 323 Gene3D G3DSA:3.40.190.10 95 203 6.2E-7 T 29-03-2018 CVS48_RS01635 3592d49ea658457373f7a1e5b93f34cb 323 Gene3D G3DSA:1.10.10.10 1 88 4.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01635 3592d49ea658457373f7a1e5b93f34cb 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.1E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS01635 3592d49ea658457373f7a1e5b93f34cb 323 SUPERFAMILY SSF46785 7 116 8.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01635 3592d49ea658457373f7a1e5b93f34cb 323 SUPERFAMILY SSF53850 92 320 9.77E-27 T 29-03-2018 CVS48_RS01635 3592d49ea658457373f7a1e5b93f34cb 323 Gene3D G3DSA:3.40.190.10 204 290 3.5E-15 T 29-03-2018 CVS48_RS01635 3592d49ea658457373f7a1e5b93f34cb 323 Pfam PF03466 LysR substrate binding domain 91 316 2.6E-22 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS26725 f7c7859cbc1b2e27b17bf6fb6e6e3424 43 Pfam PF08085 Entericidin EcnA/B family 21 41 2.5E-10 T 29-03-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 CVS48_RS03720 7d461c1a5b9df6ca27fe1da2f03d36cc 162 Gene3D G3DSA:3.40.50.620 27 148 2.8E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS03720 7d461c1a5b9df6ca27fe1da2f03d36cc 162 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 26 160 3.0E-55 T 29-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 CVS48_RS03720 7d461c1a5b9df6ca27fe1da2f03d36cc 162 SUPERFAMILY SSF52374 28 159 1.63E-21 T 29-03-2018 CVS48_RS03720 7d461c1a5b9df6ca27fe1da2f03d36cc 162 Pfam PF01467 Cytidylyltransferase-like 32 125 4.1E-14 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CVS48_RS03720 7d461c1a5b9df6ca27fe1da2f03d36cc 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 30 91 7.7E-13 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CVS48_RS26980 d7d1c11ecb70f3dbddafe44fbaec9d1e 279 SUPERFAMILY SSF56112 34 50 1.02E-10 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS26980 d7d1c11ecb70f3dbddafe44fbaec9d1e 279 SUPERFAMILY SSF56112 85 205 1.02E-10 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS26980 d7d1c11ecb70f3dbddafe44fbaec9d1e 279 Gene3D G3DSA:1.10.510.10 79 229 1.1E-6 T 29-03-2018 CVS48_RS14655 80dc05dfb13ea44823718ceceb68e170 217 Gene3D G3DSA:1.10.3720.10 1 217 2.5E-44 T 29-03-2018 CVS48_RS14655 80dc05dfb13ea44823718ceceb68e170 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 214 7.9E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS14655 80dc05dfb13ea44823718ceceb68e170 217 SUPERFAMILY SSF161098 13 206 6.67E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS14655 80dc05dfb13ea44823718ceceb68e170 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 1.5E-28 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS23325 1968224f330baefcf9536776d5c8cd80 339 Pfam PF09851 Short C-terminal domain 308 334 5.0E-7 T 29-03-2018 IPR018649 SHOCT domain CVS48_RS23325 1968224f330baefcf9536776d5c8cd80 339 SUPERFAMILY SSF117892 124 231 1.44E-12 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS23325 1968224f330baefcf9536776d5c8cd80 339 Pfam PF13421 SPFH domain-Band 7 family 26 235 1.9E-74 T 29-03-2018 IPR033880 SPFH domain, YdjI-like CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 467 1.9E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 SUPERFAMILY SSF47384 237 308 9.22E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 Gene3D G3DSA:3.30.565.10 316 473 1.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 4.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 465 4.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 4.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 4.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 SMART SM00387 354 468 6.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 SMART SM00304 200 252 6.4E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 SMART SM00388 253 312 1.8E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 Pfam PF00672 HAMP domain 202 248 8.9E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 SUPERFAMILY SSF158472 202 249 1.7E-5 T 29-03-2018 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 SUPERFAMILY SSF55874 312 469 2.75E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 308 1.5E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 66 172 9.0E-39 T 29-03-2018 IPR032408 Sensor histidine kinase RisS, periplasmic domain CVS48_RS28590 505116e5cf064f0d0580775c52cd6f7f 479 Gene3D G3DSA:1.10.287.130 243 308 6.5E-10 T 29-03-2018 CVS48_RS22355 7ed972da112c27866a07eff08a21b680 246 Pfam PF00005 ABC transporter 24 168 2.7E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22355 7ed972da112c27866a07eff08a21b680 246 SMART SM00382 32 234 8.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS22355 7ed972da112c27866a07eff08a21b680 246 PIRSF PIRSF039137 3 241 3.9E-109 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CVS48_RS22355 7ed972da112c27866a07eff08a21b680 246 SUPERFAMILY SSF52540 6 239 9.43E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS22355 7ed972da112c27866a07eff08a21b680 246 Gene3D G3DSA:3.40.50.300 2 241 1.3E-57 T 29-03-2018 CVS48_RS22355 7ed972da112c27866a07eff08a21b680 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS02525 dad3989c72ee10cba3bd411187bdedf1 354 ProSitePatterns PS00483 Dihydroorotase signature 2. 255 266 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS02525 dad3989c72ee10cba3bd411187bdedf1 354 Hamap MF_00219 Dihydroorotase [pyrC]. 7 353 43.514 T 29-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS02525 dad3989c72ee10cba3bd411187bdedf1 354 ProSitePatterns PS00482 Dihydroorotase signature 1. 16 24 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS02525 dad3989c72ee10cba3bd411187bdedf1 354 Pfam PF01979 Amidohydrolase family 16 320 1.4E-23 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS02525 dad3989c72ee10cba3bd411187bdedf1 354 Gene3D G3DSA:3.20.20.140 15 354 4.0E-50 T 29-03-2018 CVS48_RS02525 dad3989c72ee10cba3bd411187bdedf1 354 PIRSF PIRSF001237 5 354 6.1E-135 T 29-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS02525 dad3989c72ee10cba3bd411187bdedf1 354 SUPERFAMILY SSF51556 8 352 2.31E-141 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS02525 dad3989c72ee10cba3bd411187bdedf1 354 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 9 351 3.1E-138 T 29-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 333 35.76 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 3.6E-19 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 3.6E-19 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 3.6E-19 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 3.6E-19 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 Gene3D G3DSA:1.10.240.10 198 328 2.8E-23 T 29-03-2018 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 Pfam PF00579 tRNA synthetases class I (W and Y) 3 287 5.7E-54 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 Gene3D G3DSA:3.40.50.620 1 197 8.4E-62 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 SUPERFAMILY SSF52374 4 332 4.79E-79 T 29-03-2018 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 332 5.9E-95 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CVS48_RS27715 4dd63693bfc84bf8ab8f65aa334f9023 450 SUPERFAMILY SSF160113 354 405 1.1E-8 T 29-03-2018 IPR010879 Domain of unknown function DUF1508 CVS48_RS05650 525c3990982862f518b2686c54b952ee 196 SUPERFAMILY SSF140931 36 194 4.05E-31 T 29-03-2018 IPR003812 Fido domain CVS48_RS05650 525c3990982862f518b2686c54b952ee 196 Pfam PF02661 Fic/DOC family 58 149 2.2E-14 T 29-03-2018 IPR003812 Fido domain CVS48_RS05650 525c3990982862f518b2686c54b952ee 196 TIGRFAM TIGR02613 mob_myst_B: mobile mystery protein B 12 195 4.5E-72 T 29-03-2018 IPR013436 Mobile mystery protein B CVS48_RS05650 525c3990982862f518b2686c54b952ee 196 Gene3D G3DSA:1.10.3290.10 11 196 2.1E-32 T 29-03-2018 IPR003812 Fido domain CVS48_RS05005 5cb067560eb711aa26297dc94cd85a5a 288 Pfam PF00756 Putative esterase 25 278 2.4E-51 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CVS48_RS05005 5cb067560eb711aa26297dc94cd85a5a 288 Gene3D G3DSA:3.40.50.1820 2 283 2.1E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS05005 5cb067560eb711aa26297dc94cd85a5a 288 SUPERFAMILY SSF53474 5 284 6.89E-86 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS05005 5cb067560eb711aa26297dc94cd85a5a 288 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 6 283 4.3E-136 T 29-03-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 CVS48_RS05660 17bb4864622b35f314838d29295262b6 397 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS05660 17bb4864622b35f314838d29295262b6 397 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 8 392 41.208 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CVS48_RS05660 17bb4864622b35f314838d29295262b6 397 PIRSF PIRSF000521 18 394 2.1E-41 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS05660 17bb4864622b35f314838d29295262b6 397 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 12 391 3.7E-125 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CVS48_RS05660 17bb4864622b35f314838d29295262b6 397 Gene3D G3DSA:3.40.640.10 45 282 6.2E-73 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS05660 17bb4864622b35f314838d29295262b6 397 Gene3D G3DSA:3.90.1150.10 283 397 5.3E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS05660 17bb4864622b35f314838d29295262b6 397 Pfam PF00202 Aminotransferase class-III 20 389 2.0E-102 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS05660 17bb4864622b35f314838d29295262b6 397 SUPERFAMILY SSF53383 12 391 1.95E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS13990 f6f2806f6ee63c76709499c5bbe45a4b 189 SUPERFAMILY SSF47240 69 186 1.66E-5 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS13990 f6f2806f6ee63c76709499c5bbe45a4b 189 Gene3D G3DSA:1.20.1260.10 34 184 3.8E-24 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS13990 f6f2806f6ee63c76709499c5bbe45a4b 189 Pfam PF13628 Domain of unknown function (DUF4142) 45 180 1.2E-39 T 29-03-2018 IPR025419 Domain of unknown function DUF4142 CVS48_RS09540 0f4f9b4aa1e910b8927d574c22e2f7f0 961 SUPERFAMILY SSF69360 93 175 2.16E-5 T 29-03-2018 CVS48_RS09540 0f4f9b4aa1e910b8927d574c22e2f7f0 961 Pfam PF14903 WG containing repeat 886 914 0.0018 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09540 0f4f9b4aa1e910b8927d574c22e2f7f0 961 Pfam PF14903 WG containing repeat 236 265 4.7E-4 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09540 0f4f9b4aa1e910b8927d574c22e2f7f0 961 Pfam PF14903 WG containing repeat 598 628 0.036 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09540 0f4f9b4aa1e910b8927d574c22e2f7f0 961 Pfam PF14903 WG containing repeat 94 128 1.0E-9 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09540 0f4f9b4aa1e910b8927d574c22e2f7f0 961 Pfam PF14903 WG containing repeat 128 161 4.8E-8 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS23330 0c24ba6ae47820778757591fb688a5fc 128 Pfam PF03994 Domain of Unknown Function (DUF350) 75 127 7.3E-9 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CVS48_RS23330 0c24ba6ae47820778757591fb688a5fc 128 Pfam PF03994 Domain of Unknown Function (DUF350) 10 63 1.0E-10 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CVS48_RS03935 452727e1f79ad507445049764dc1481b 374 Pfam PF07883 Cupin domain 107 174 1.1E-16 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS03935 452727e1f79ad507445049764dc1481b 374 Pfam PF07883 Cupin domain 279 346 3.0E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS03935 452727e1f79ad507445049764dc1481b 374 Gene3D G3DSA:2.60.120.10 47 366 3.0E-36 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS03935 452727e1f79ad507445049764dc1481b 374 SUPERFAMILY SSF51182 22 371 7.31E-115 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS26020 0dccaccf7ec437576de62bb718a997cb 261 SUPERFAMILY SSF56529 12 259 1.98E-41 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS26020 0dccaccf7ec437576de62bb718a997cb 261 Gene3D G3DSA:3.90.850.10 7 261 4.9E-22 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS26020 0dccaccf7ec437576de62bb718a997cb 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 65 235 4.4E-7 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS03870 31721396817c7e0e452d946eb9a97ad3 523 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 7 514 4.4E-191 T 29-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CVS48_RS03870 31721396817c7e0e452d946eb9a97ad3 523 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 523 208.537 T 29-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CVS48_RS03870 31721396817c7e0e452d946eb9a97ad3 523 Pfam PF04262 Glutamate-cysteine ligase 14 376 1.2E-155 T 29-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CVS48_RS03870 31721396817c7e0e452d946eb9a97ad3 523 SUPERFAMILY SSF55931 9 511 1.57E-182 T 29-03-2018 CVS48_RS26745 69d7ad537b556f4a117cc888689788f8 230 SMART SM00382 26 207 9.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS26745 69d7ad537b556f4a117cc888689788f8 230 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS26745 69d7ad537b556f4a117cc888689788f8 230 Pfam PF00005 ABC transporter 17 158 1.9E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS26745 69d7ad537b556f4a117cc888689788f8 230 SUPERFAMILY SSF52540 2 223 3.09E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26745 69d7ad537b556f4a117cc888689788f8 230 Gene3D G3DSA:3.40.50.300 1 228 4.4E-54 T 29-03-2018 CVS48_RS25070 9132f262e1c9925f11fe5701a640b23c 322 SUPERFAMILY SSF53850 115 280 1.28E-11 T 29-03-2018 CVS48_RS25070 9132f262e1c9925f11fe5701a640b23c 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 316 2.4E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25070 9132f262e1c9925f11fe5701a640b23c 322 Gene3D G3DSA:3.40.190.10 121 232 2.0E-9 T 29-03-2018 CVS48_RS25070 9132f262e1c9925f11fe5701a640b23c 322 PIRSF PIRSF017082 2 322 3.2E-69 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 Gene3D G3DSA:2.160.10.10 246 320 3.0E-15 T 29-03-2018 CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 268 300 1.3E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 320 353 1.6E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 396 430 1.2E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 327 355 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 Pfam PF12804 MobA-like NTP transferase domain 4 129 4.5E-25 T 29-03-2018 IPR025877 MobA-like NTP transferase CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 3 456 1.9E-188 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 453 42.283 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 Gene3D G3DSA:2.160.10.10 321 445 1.5E-32 T 29-03-2018 CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 SUPERFAMILY SSF53448 2 253 1.61E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 Gene3D G3DSA:3.90.550.10 2 245 7.1E-52 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS04905 e8ef3c6546f9fa7a48afa23dad612c40 457 SUPERFAMILY SSF51161 256 438 3.49E-49 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS18860 cffb6ae3103997757fa147d3970816a9 359 Gene3D G3DSA:1.10.150.130 18 156 1.6E-11 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CVS48_RS18860 cffb6ae3103997757fa147d3970816a9 359 Pfam PF00589 Phage integrase family 163 338 1.6E-14 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS18860 cffb6ae3103997757fa147d3970816a9 359 SUPERFAMILY SSF56349 159 352 6.77E-34 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS18860 cffb6ae3103997757fa147d3970816a9 359 SUPERFAMILY SSF47823 28 76 8.24E-12 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CVS48_RS18860 cffb6ae3103997757fa147d3970816a9 359 SUPERFAMILY SSF47823 105 153 8.24E-12 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CVS48_RS18860 cffb6ae3103997757fa147d3970816a9 359 Gene3D G3DSA:1.10.443.10 158 341 4.1E-25 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS18190 cdf9341dcd8ca88760ace293c3f7e42c 265 Pfam PF01841 Transglutaminase-like superfamily 126 217 2.7E-16 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS18190 cdf9341dcd8ca88760ace293c3f7e42c 265 SUPERFAMILY SSF54001 7 246 1.21E-26 T 29-03-2018 CVS48_RS18190 cdf9341dcd8ca88760ace293c3f7e42c 265 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 5 79 1.1E-18 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CVS48_RS18190 cdf9341dcd8ca88760ace293c3f7e42c 265 SMART SM00460 158 220 3.4E-7 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS09560 e6edf3fc63404de7fd1e055266ed6c56 180 Gene3D G3DSA:2.60.120.480 5 170 3.8E-24 T 29-03-2018 IPR024060 Ureidoglycolate lyase domain GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CVS48_RS09560 e6edf3fc63404de7fd1e055266ed6c56 180 Pfam PF04115 Ureidoglycolate lyase 56 134 2.8E-12 T 29-03-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CVS48_RS09560 e6edf3fc63404de7fd1e055266ed6c56 180 SUPERFAMILY SSF51182 6 159 7.29E-26 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS26825 05388653a2a70286284927f05f752420 200 Pfam PF11136 Protein of unknown function (DUF2889) 14 138 4.8E-44 T 29-03-2018 IPR021312 Protein of unknown function DUF2889 CVS48_RS17315 5f2bc3fff171e5a34655f9b2cc9ea3cd 246 SMART SM00346 7 95 2.6E-7 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS17315 5f2bc3fff171e5a34655f9b2cc9ea3cd 246 Gene3D G3DSA:1.10.10.10 8 64 7.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17315 5f2bc3fff171e5a34655f9b2cc9ea3cd 246 Pfam PF01614 Bacterial transcriptional regulator 127 241 4.1E-15 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS17315 5f2bc3fff171e5a34655f9b2cc9ea3cd 246 SUPERFAMILY SSF46785 10 76 3.76E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17315 5f2bc3fff171e5a34655f9b2cc9ea3cd 246 Gene3D G3DSA:3.30.450.40 77 246 7.1E-37 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS17315 5f2bc3fff171e5a34655f9b2cc9ea3cd 246 SUPERFAMILY SSF55781 72 244 1.96E-35 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS17315 5f2bc3fff171e5a34655f9b2cc9ea3cd 246 Pfam PF09339 IclR helix-turn-helix domain 10 58 7.9E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS01470 f0089aedb1f87c2fc98932e5154e58e4 447 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 435 7.1E-95 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CVS48_RS01470 f0089aedb1f87c2fc98932e5154e58e4 447 PIRSF PIRSF006446 1 442 1.5E-93 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CVS48_RS02115 e81853128d949816762542ba3da61cd2 171 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 12 164 1.6E-59 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CVS48_RS02115 e81853128d949816762542ba3da61cd2 171 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 8 165 6.4E-58 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CVS48_RS02115 e81853128d949816762542ba3da61cd2 171 PIRSF PIRSF028301 2 171 4.3E-65 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CVS48_RS02090 d393bba04916df280a78ecec360d7afe 351 Pfam PF06996 Type VI secretion, TssG 7 331 5.9E-92 T 29-03-2018 IPR010732 Type VI secretion, TssG-like CVS48_RS02090 d393bba04916df280a78ecec360d7afe 351 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 7 331 5.9E-100 T 29-03-2018 IPR010732 Type VI secretion, TssG-like CVS48_RS08145 53479a5d11b33c572f1052fcc6b71770 350 Pfam PF08900 Domain of unknown function (DUF1845) 101 318 4.9E-51 T 29-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 CVS48_RS08145 53479a5d11b33c572f1052fcc6b71770 350 TIGRFAM TIGR03761 ICE_PFL4669: integrating conjugative element protein, PFL_4669 family 99 318 3.3E-39 T 29-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 CVS48_RS26775 a267222b2e41f46a664365b12830ad19 278 Pfam PF09339 IclR helix-turn-helix domain 5 51 3.1E-7 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS26775 a267222b2e41f46a664365b12830ad19 278 Gene3D G3DSA:3.30.450.40 81 257 7.8E-32 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS26775 a267222b2e41f46a664365b12830ad19 278 Pfam PF01614 Bacterial transcriptional regulator 121 242 7.4E-12 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS26775 a267222b2e41f46a664365b12830ad19 278 SUPERFAMILY SSF46785 2 72 1.29E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26775 a267222b2e41f46a664365b12830ad19 278 SUPERFAMILY SSF55781 58 244 3.4E-28 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS26775 a267222b2e41f46a664365b12830ad19 278 Gene3D G3DSA:1.10.10.10 1 80 2.3E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26775 a267222b2e41f46a664365b12830ad19 278 SMART SM00346 1 90 1.8E-7 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS13145 c07a19d4969387a83a2c025ee3f22ae5 327 Gene3D G3DSA:3.40.190.10 135 294 1.6E-11 T 29-03-2018 CVS48_RS13145 c07a19d4969387a83a2c025ee3f22ae5 327 PIRSF PIRSF017082 1 326 4.1E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13145 c07a19d4969387a83a2c025ee3f22ae5 327 SUPERFAMILY SSF53850 115 289 1.22E-13 T 29-03-2018 CVS48_RS13145 c07a19d4969387a83a2c025ee3f22ae5 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 320 4.0E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS02405 57a1dc182088b8fd81840c7f3540cc7c 328 PIRSF PIRSF017082 1 326 4.0E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS02405 57a1dc182088b8fd81840c7f3540cc7c 328 Gene3D G3DSA:3.40.190.10 36 298 1.9E-10 T 29-03-2018 CVS48_RS02405 57a1dc182088b8fd81840c7f3540cc7c 328 SUPERFAMILY SSF53850 155 288 9.05E-9 T 29-03-2018 CVS48_RS02405 57a1dc182088b8fd81840c7f3540cc7c 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 323 5.2E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 Gene3D G3DSA:1.20.210.10 53 571 2.3E-186 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 290 344 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 SUPERFAMILY SSF81442 53 569 2.09E-177 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 66 513 1.6E-136 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 57 82 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 226 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 379 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 411 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 188 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 309 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 134 158 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 421 440 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 107 130 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 334 349 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 471 492 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 256 8.1E-95 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 Gene3D G3DSA:1.10.287.70 584 649 1.2E-10 T 29-03-2018 CVS48_RS12105 82f5ce0888baae1e853f6b1221a6768a 667 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 12 654 0.0 T 29-03-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 CVS48_RS25990 0f10d7ebb08d789458cfaaee1e641419 412 SUPERFAMILY SSF103473 11 398 3.14E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS25990 0f10d7ebb08d789458cfaaee1e641419 412 Gene3D G3DSA:1.20.1250.20 210 411 2.2E-14 T 29-03-2018 CVS48_RS25990 0f10d7ebb08d789458cfaaee1e641419 412 Gene3D G3DSA:1.20.1250.20 16 207 1.9E-25 T 29-03-2018 CVS48_RS25990 0f10d7ebb08d789458cfaaee1e641419 412 Pfam PF07690 Major Facilitator Superfamily 29 331 2.4E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS05300 39b7b89651bb3a9b9dc74e37be75546d 157 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 8 146 3.7E-28 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS05300 39b7b89651bb3a9b9dc74e37be75546d 157 Gene3D G3DSA:3.30.1330.40 1 154 4.9E-30 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS05300 39b7b89651bb3a9b9dc74e37be75546d 157 SUPERFAMILY SSF55298 4 153 1.54E-49 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS12605 70a9aa1029a1f0055969fb1e8d756da3 361 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 241 260 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CVS48_RS12605 70a9aa1029a1f0055969fb1e8d756da3 361 SUPERFAMILY SSF53659 1 352 2.5E-111 T 29-03-2018 CVS48_RS12605 70a9aa1029a1f0055969fb1e8d756da3 361 Gene3D G3DSA:3.40.718.10 1 210 6.9E-67 T 29-03-2018 CVS48_RS12605 70a9aa1029a1f0055969fb1e8d756da3 361 Gene3D G3DSA:3.40.718.10 211 353 2.0E-53 T 29-03-2018 CVS48_RS12605 70a9aa1029a1f0055969fb1e8d756da3 361 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 347 5.3E-83 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CVS48_RS12605 70a9aa1029a1f0055969fb1e8d756da3 361 SMART SM01329 5 348 3.9E-162 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CVS48_RS12605 70a9aa1029a1f0055969fb1e8d756da3 361 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 352 8.3E-166 T 29-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CVS48_RS26340 07be4abd4a3d5f0e800d674f60c759f8 407 Pfam PF00202 Aminotransferase class-III 12 382 3.9E-111 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS26340 07be4abd4a3d5f0e800d674f60c759f8 407 PIRSF PIRSF000521 161 388 4.0E-32 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS26340 07be4abd4a3d5f0e800d674f60c759f8 407 PIRSF PIRSF000521 5 150 2.1E-12 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS26340 07be4abd4a3d5f0e800d674f60c759f8 407 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 7 382 1.7E-138 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CVS48_RS26340 07be4abd4a3d5f0e800d674f60c759f8 407 Gene3D G3DSA:3.40.640.10 48 279 2.9E-70 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS26340 07be4abd4a3d5f0e800d674f60c759f8 407 SUPERFAMILY SSF53383 6 385 2.23E-122 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS26340 07be4abd4a3d5f0e800d674f60c759f8 407 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 2 386 44.698 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CVS48_RS26340 07be4abd4a3d5f0e800d674f60c759f8 407 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 212 249 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CVS48_RS26340 07be4abd4a3d5f0e800d674f60c759f8 407 Gene3D G3DSA:3.90.1150.10 280 389 5.6E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS15820 d89669afde71ccf5a27de98cac8543e9 294 Gene3D G3DSA:3.90.226.10 6 265 2.4E-32 T 29-03-2018 CVS48_RS15820 d89669afde71ccf5a27de98cac8543e9 294 SUPERFAMILY SSF52096 25 265 1.76E-32 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS15820 d89669afde71ccf5a27de98cac8543e9 294 Pfam PF00378 Enoyl-CoA hydratase/isomerase 75 217 5.6E-14 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS05115 0f8b421bf4f562a0e1b7c83c6cef6f4f 232 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 230 33.978 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CVS48_RS05115 0f8b421bf4f562a0e1b7c83c6cef6f4f 232 Pfam PF00117 Glutamine amidotransferase class-I 6 227 1.3E-16 T 29-03-2018 IPR017926 Glutamine amidotransferase CVS48_RS05115 0f8b421bf4f562a0e1b7c83c6cef6f4f 232 SUPERFAMILY SSF52317 3 113 1.67E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS05115 0f8b421bf4f562a0e1b7c83c6cef6f4f 232 SUPERFAMILY SSF52317 142 230 1.67E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS05115 0f8b421bf4f562a0e1b7c83c6cef6f4f 232 PIRSF PIRSF000495 130 232 1.1E-29 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CVS48_RS05115 0f8b421bf4f562a0e1b7c83c6cef6f4f 232 PIRSF PIRSF000495 2 121 1.1E-32 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CVS48_RS05115 0f8b421bf4f562a0e1b7c83c6cef6f4f 232 Gene3D G3DSA:3.40.50.880 1 230 5.0E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS05115 0f8b421bf4f562a0e1b7c83c6cef6f4f 232 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 141 229 3.4E-31 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CVS48_RS07060 485ca9c0f52de5628cffeba9c0ce6129 345 Gene3D G3DSA:3.20.20.70 1 272 2.2E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS07060 485ca9c0f52de5628cffeba9c0ce6129 345 SUPERFAMILY SSF51269 282 344 9.42E-10 T 29-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 CVS48_RS07060 485ca9c0f52de5628cffeba9c0ce6129 345 SUPERFAMILY SSF51569 3 279 1.47E-44 T 29-03-2018 CVS48_RS07060 485ca9c0f52de5628cffeba9c0ce6129 345 Pfam PF08666 SAF domain 291 339 1.1E-5 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS07060 485ca9c0f52de5628cffeba9c0ce6129 345 Pfam PF03102 NeuB family 27 270 6.0E-45 T 29-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 CVS48_RS07060 485ca9c0f52de5628cffeba9c0ce6129 345 Gene3D G3DSA:3.90.1210.10 278 344 1.3E-13 T 29-03-2018 CVS48_RS07060 485ca9c0f52de5628cffeba9c0ce6129 345 SMART SM00858 287 345 4.1E-4 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 SMART SM01086 316 411 1.6E-34 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 309 3.2E-47 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 1.1E-198 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 Gene3D G3DSA:3.40.50.300 56 314 5.8E-69 T 29-03-2018 CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 SUPERFAMILY SSF52540 62 398 7.51E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 SMART SM00994 12 51 1.7E-23 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 SMART SM00382 112 332 8.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 6 414 52.333 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 Pfam PF06689 ClpX C4-type zinc finger 13 50 4.7E-19 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 316 394 2.5E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 Gene3D G3DSA:1.10.8.60 316 407 8.7E-32 T 29-03-2018 CVS48_RS21965 a5e692b344b697ec96a2a6d8120be275 432 SUPERFAMILY SSF57716 13 48 3.85E-11 T 29-03-2018 CVS48_RS04015 60ac68724e1c30d643a75e4d4a888464 305 SUPERFAMILY SSF161098 99 291 8.37E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS04015 60ac68724e1c30d643a75e4d4a888464 305 Gene3D G3DSA:1.10.3720.10 24 296 1.5E-43 T 29-03-2018 CVS48_RS04015 60ac68724e1c30d643a75e4d4a888464 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 304 1.8E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 7 949 18.867 T 29-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 410 430 8.9E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 196 212 8.9E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 625 654 8.9E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 144 157 8.9E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 764 790 8.9E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 583 603 8.9E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 259 274 8.9E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 Pfam PF00311 Phosphoenolpyruvate carboxylase 141 949 3.5E-286 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 SUPERFAMILY SSF51621 15 949 2.83E-285 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 Gene3D G3DSA:1.20.1440.90 289 412 7.3E-24 T 29-03-2018 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 585 597 - T 29-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS09230 b44e0e13bfdabc228ca9b9ac24fe2875 949 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 145 156 - T 29-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CVS48_RS01855 286e97d34cc8fcfea9c17eaa41fb8805 397 Pfam PF02515 CoA-transferase family III 9 374 1.0E-106 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS01855 286e97d34cc8fcfea9c17eaa41fb8805 397 SUPERFAMILY SSF89796 3 397 4.84E-122 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS01855 286e97d34cc8fcfea9c17eaa41fb8805 397 Gene3D G3DSA:3.40.50.10540 3 397 2.3E-123 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS09310 23c76b529c418bac04a425c2aae66403 313 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 300 8.6E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS09310 23c76b529c418bac04a425c2aae66403 313 Gene3D G3DSA:1.10.3470.10 1 306 2.6E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS10995 0a45afc17be5ec270a1bef845d19d7c9 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 262 6.5E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10995 0a45afc17be5ec270a1bef845d19d7c9 274 SUPERFAMILY SSF161098 78 263 1.01E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10995 0a45afc17be5ec270a1bef845d19d7c9 274 Gene3D G3DSA:1.10.3720.10 74 274 5.8E-24 T 29-03-2018 CVS48_RS10995 0a45afc17be5ec270a1bef845d19d7c9 274 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 24 273 3.3E-88 T 29-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 SUPERFAMILY SSF54292 218 323 1.06E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 246 316 4.4E-9 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 Gene3D G3DSA:3.40.50.80 109 227 8.4E-23 T 29-03-2018 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 Gene3D G3DSA:3.10.20.30 228 325 2.4E-20 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 274 282 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 SUPERFAMILY SSF63380 2 104 2.87E-17 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 Pfam PF00175 Oxidoreductase NAD-binding domain 120 209 7.1E-8 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 PRINTS PR00409 Phthalate dioxygenase reductase family signature 51 65 2.0E-8 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 PRINTS PR00409 Phthalate dioxygenase reductase family signature 144 153 2.0E-8 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 PRINTS PR00409 Phthalate dioxygenase reductase family signature 28 38 2.0E-8 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 PRINTS PR00409 Phthalate dioxygenase reductase family signature 196 204 2.0E-8 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 Gene3D G3DSA:2.40.30.10 2 105 6.8E-15 T 29-03-2018 CVS48_RS01570 743c421b6fad5086951a07ed54fa0e4e 325 SUPERFAMILY SSF52343 102 233 1.44E-30 T 29-03-2018 CVS48_RS12205 571837ae9b7c0d7c0791c2f41661bba6 809 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 168 809 2.8E-107 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS12205 571837ae9b7c0d7c0791c2f41661bba6 809 SMART SM00965 75 125 1.1E-9 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS12205 571837ae9b7c0d7c0791c2f41661bba6 809 Gene3D G3DSA:2.40.170.20 277 809 4.8E-74 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12205 571837ae9b7c0d7c0791c2f41661bba6 809 Pfam PF00593 TonB dependent receptor 350 807 1.7E-45 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS12205 571837ae9b7c0d7c0791c2f41661bba6 809 Gene3D G3DSA:2.170.130.10 123 274 8.1E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS12205 571837ae9b7c0d7c0791c2f41661bba6 809 SUPERFAMILY SSF56935 130 809 1.34E-115 T 29-03-2018 CVS48_RS12205 571837ae9b7c0d7c0791c2f41661bba6 809 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 792 809 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS12205 571837ae9b7c0d7c0791c2f41661bba6 809 Pfam PF07660 Secretin and TonB N terminus short domain 76 124 3.0E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS12205 571837ae9b7c0d7c0791c2f41661bba6 809 Pfam PF07715 TonB-dependent Receptor Plug Domain 166 266 4.4E-12 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 195 5.9E-4 T 29-03-2018 CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 3.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 Gene3D G3DSA:3.40.50.720 1 187 3.2E-54 T 29-03-2018 CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 Pfam PF00106 short chain dehydrogenase 16 199 1.0E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 SUPERFAMILY SSF51735 9 240 4.79E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS25695 2dd88b46b4c0a66746c91ff5a49b2af9 247 Gene3D G3DSA:3.40.50.720 188 239 0.0053 T 29-03-2018 CVS48_RS02150 80efe76f9646954add09caea49ecc3e3 772 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 317 437 2.8E-8 T 29-03-2018 IPR018712 Domain of unknown function DUF2235 CVS48_RS14020 09b6d0335a1b7073d07fd8f5e882a197 408 Pfam PF02515 CoA-transferase family III 19 384 9.5E-110 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS14020 09b6d0335a1b7073d07fd8f5e882a197 408 Gene3D G3DSA:3.40.50.10540 14 408 8.1E-119 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS14020 09b6d0335a1b7073d07fd8f5e882a197 408 SUPERFAMILY SSF89796 15 407 5.62E-118 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS00795 53fb3c1fc3461073bfed17ea50a786aa 369 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 41 55 1.3E-8 T 29-03-2018 CVS48_RS00795 53fb3c1fc3461073bfed17ea50a786aa 369 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 101 113 1.3E-8 T 29-03-2018 CVS48_RS00795 53fb3c1fc3461073bfed17ea50a786aa 369 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 130 154 1.3E-8 T 29-03-2018 CVS48_RS00795 53fb3c1fc3461073bfed17ea50a786aa 369 SUPERFAMILY SSF53335 18 191 2.11E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS00795 53fb3c1fc3461073bfed17ea50a786aa 369 Gene3D G3DSA:3.40.50.150 5 201 7.0E-19 T 29-03-2018 CVS48_RS00795 53fb3c1fc3461073bfed17ea50a786aa 369 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 104 110 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 Gene3D G3DSA:3.90.380.10 151 424 2.3E-63 T 29-03-2018 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 110 130 4.9E-28 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 38 63 4.9E-28 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 89 109 4.9E-28 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 149 175 4.9E-28 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 68 83 4.9E-28 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 187 209 4.9E-28 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 SUPERFAMILY SSF50022 21 164 3.27E-48 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 Pfam PF00355 Rieske [2Fe-2S] domain 53 133 9.7E-18 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 187 419 3.4E-50 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 SUPERFAMILY SSF55961 175 227 5.42E-49 T 29-03-2018 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 SUPERFAMILY SSF55961 254 417 5.42E-49 T 29-03-2018 CVS48_RS01140 9f426b34cf8f1cfdae1a15629d24ac63 425 Gene3D G3DSA:2.102.10.10 51 150 2.8E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS20795 6d0e6761cfd8aa1ee49f7f9614bf9ab9 134 SUPERFAMILY SSF49764 22 133 1.5E-27 T 29-03-2018 IPR008978 HSP20-like chaperone CVS48_RS20795 6d0e6761cfd8aa1ee49f7f9614bf9ab9 134 Pfam PF00011 Hsp20/alpha crystallin family 33 132 4.9E-19 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CVS48_RS20795 6d0e6761cfd8aa1ee49f7f9614bf9ab9 134 Gene3D G3DSA:2.60.40.790 2 134 4.9E-26 T 29-03-2018 IPR008978 HSP20-like chaperone CVS48_RS01860 55068939b76ccb470ecf716e622cae4e 276 Gene3D G3DSA:3.10.129.10 158 275 2.2E-17 T 29-03-2018 CVS48_RS01860 55068939b76ccb470ecf716e622cae4e 276 SUPERFAMILY SSF54637 163 273 6.15E-14 T 29-03-2018 IPR029069 HotDog domain CVS48_RS01860 55068939b76ccb470ecf716e622cae4e 276 SUPERFAMILY SSF54637 43 146 7.46E-7 T 29-03-2018 IPR029069 HotDog domain CVS48_RS01860 55068939b76ccb470ecf716e622cae4e 276 Gene3D G3DSA:3.10.129.10 4 157 1.2E-13 T 29-03-2018 CVS48_RS01860 55068939b76ccb470ecf716e622cae4e 276 Pfam PF13452 N-terminal half of MaoC dehydratase 74 136 3.7E-6 T 29-03-2018 CVS48_RS23595 9619645c205ba18cf43625af7c5693b8 457 SUPERFAMILY SSF52540 72 399 1.44E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23595 9619645c205ba18cf43625af7c5693b8 457 Gene3D G3DSA:3.40.50.300 191 439 1.5E-18 T 29-03-2018 CVS48_RS23595 9619645c205ba18cf43625af7c5693b8 457 Gene3D G3DSA:3.30.450.90 87 190 4.7E-36 T 29-03-2018 CVS48_RS23595 9619645c205ba18cf43625af7c5693b8 457 Pfam PF00437 Type II/IV secretion system protein 92 368 2.6E-78 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS14365 ee70917810908801ce8ff962ff167416 325 Gene3D G3DSA:3.90.1480.10 74 324 9.3E-31 T 29-03-2018 CVS48_RS14365 ee70917810908801ce8ff962ff167416 325 ProDom PD024016 LIPOPOLYSACCHARIDE BIOSYNTHESIS CORE RFAZ WAAZ 75 308 1.0E-13 T 29-03-2018 CVS48_RS13195 20613dd9aaadd6417146722d3cf48e5a 204 SUPERFAMILY SSF52833 1 86 8.31E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS13195 20613dd9aaadd6417146722d3cf48e5a 204 SUPERFAMILY SSF47616 89 198 3.69E-16 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS13195 20613dd9aaadd6417146722d3cf48e5a 204 Gene3D G3DSA:3.40.30.10 2 110 2.3E-24 T 29-03-2018 CVS48_RS13195 20613dd9aaadd6417146722d3cf48e5a 204 Pfam PF13410 Glutathione S-transferase, C-terminal domain 130 184 1.2E-6 T 29-03-2018 CVS48_RS13195 20613dd9aaadd6417146722d3cf48e5a 204 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 76 1.1E-14 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS13195 20613dd9aaadd6417146722d3cf48e5a 204 Gene3D G3DSA:1.20.1050.10 111 204 2.7E-12 T 29-03-2018 CVS48_RS16005 56d313657a72a4032e1b5c59b9861c73 485 PIRSF PIRSF016636 1 485 8.0E-149 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CVS48_RS16005 56d313657a72a4032e1b5c59b9861c73 485 PIRSF PIRSF500217 1 485 1.4E-147 T 29-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CVS48_RS16005 56d313657a72a4032e1b5c59b9861c73 485 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 151 351 1.4E-30 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CVS48_RS09360 5f52fcd37ba0014c1ec9174f74efd644 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CVS48_RS09360 5f52fcd37ba0014c1ec9174f74efd644 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 253 7.7E-35 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS09360 5f52fcd37ba0014c1ec9174f74efd644 338 Gene3D G3DSA:3.40.190.10 24 136 2.8E-18 T 29-03-2018 CVS48_RS09360 5f52fcd37ba0014c1ec9174f74efd644 338 SMART SM00062 34 263 8.9E-51 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS09360 5f52fcd37ba0014c1ec9174f74efd644 338 SUPERFAMILY SSF53850 25 254 1.86E-51 T 29-03-2018 CVS48_RS09360 5f52fcd37ba0014c1ec9174f74efd644 338 Gene3D G3DSA:3.40.190.10 137 226 1.1E-19 T 29-03-2018 CVS48_RS27490 24ddbc1365f206a641b0d5a89a8ff318 119 SMART SM00411 1 91 5.2E-36 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS27490 24ddbc1365f206a641b0d5a89a8ff318 119 Gene3D G3DSA:4.10.520.10 1 98 8.7E-29 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CVS48_RS27490 24ddbc1365f206a641b0d5a89a8ff318 119 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 2 91 1.9E-37 T 29-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 CVS48_RS27490 24ddbc1365f206a641b0d5a89a8ff318 119 Pfam PF00216 Bacterial DNA-binding protein 1 90 8.0E-28 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS27490 24ddbc1365f206a641b0d5a89a8ff318 119 SUPERFAMILY SSF47729 1 91 1.62E-28 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CVS48_RS27490 24ddbc1365f206a641b0d5a89a8ff318 119 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 7.7E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS27490 24ddbc1365f206a641b0d5a89a8ff318 119 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 7.7E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS27490 24ddbc1365f206a641b0d5a89a8ff318 119 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 7.7E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CVS48_RS11095 305cb61268b09861f4bcf2211816d239 288 Gene3D G3DSA:3.90.850.10 14 285 1.9E-83 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS11095 305cb61268b09861f4bcf2211816d239 288 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 278 2.5E-71 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS11095 305cb61268b09861f4bcf2211816d239 288 SUPERFAMILY SSF56529 60 280 1.44E-82 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS21870 2b3d7755bfd4288dd99ef2210bf00eff 267 Gene3D G3DSA:1.10.12.10 225 267 1.6E-14 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS21870 2b3d7755bfd4288dd99ef2210bf00eff 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 267 5.2E-48 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS21870 2b3d7755bfd4288dd99ef2210bf00eff 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS21870 2b3d7755bfd4288dd99ef2210bf00eff 267 SUPERFAMILY SSF52096 7 266 6.64E-71 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS21870 2b3d7755bfd4288dd99ef2210bf00eff 267 Gene3D G3DSA:3.90.226.10 10 224 1.4E-54 T 29-03-2018 CVS48_RS02785 ccf47135a023007f114f84c79cb60653 130 Pfam PF04138 GtrA-like protein 11 125 1.0E-14 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CVS48_RS05840 fa9c592074ea97ff92d1f843731cf5ec 387 Pfam PF01266 FAD dependent oxidoreductase 10 353 2.4E-61 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS05840 fa9c592074ea97ff92d1f843731cf5ec 387 Gene3D G3DSA:3.50.50.60 2 387 3.9E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05840 fa9c592074ea97ff92d1f843731cf5ec 387 SUPERFAMILY SSF51905 9 221 1.2E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05840 fa9c592074ea97ff92d1f843731cf5ec 387 SUPERFAMILY SSF51905 314 374 1.2E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00755 47449feee4f9abeaeb0e1f9875c42dd8 182 Gene3D G3DSA:3.20.20.70 83 176 0.0012 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS00755 47449feee4f9abeaeb0e1f9875c42dd8 182 TIGRFAM TIGR03765 ICE_PFL_4695: integrating conjugative element protein, PFL_4695 family 78 182 1.2E-42 T 29-03-2018 IPR021300 Integrating conjugative element protein, PFL4695 CVS48_RS00755 47449feee4f9abeaeb0e1f9875c42dd8 182 Pfam PF11072 Protein of unknown function (DUF2859) 34 180 4.0E-55 T 29-03-2018 IPR021300 Integrating conjugative element protein, PFL4695 CVS48_RS03110 6048de495326e7af59e69e3166ad7f3d 1168 SUPERFAMILY SSF53323 723 955 1.7E-24 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CVS48_RS03110 6048de495326e7af59e69e3166ad7f3d 1168 SUPERFAMILY SSF52922 282 371 6.54E-6 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CVS48_RS03110 6048de495326e7af59e69e3166ad7f3d 1168 Gene3D G3DSA:3.40.50.970 345 635 8.5E-33 T 29-03-2018 CVS48_RS03110 6048de495326e7af59e69e3166ad7f3d 1168 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 731 918 1.2E-20 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CVS48_RS03110 6048de495326e7af59e69e3166ad7f3d 1168 SUPERFAMILY SSF52518 435 616 9.89E-10 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS03110 6048de495326e7af59e69e3166ad7f3d 1168 Gene3D G3DSA:3.40.920.10 722 935 7.9E-46 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CVS48_RS03110 6048de495326e7af59e69e3166ad7f3d 1168 SUPERFAMILY SSF52518 26 232 2.59E-14 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS03110 6048de495326e7af59e69e3166ad7f3d 1168 Gene3D G3DSA:3.40.50.970 24 305 1.9E-18 T 29-03-2018 CVS48_RS19130 a85417a1188773b3e821911fa7e1844c 376 Pfam PF00793 DAHP synthetase I family 61 358 7.8E-100 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CVS48_RS19130 a85417a1188773b3e821911fa7e1844c 376 PIRSF PIRSF001361 14 373 8.9E-163 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CVS48_RS19130 a85417a1188773b3e821911fa7e1844c 376 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 26 370 2.0E-154 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CVS48_RS19130 a85417a1188773b3e821911fa7e1844c 376 SUPERFAMILY SSF51569 27 369 6.18E-132 T 29-03-2018 CVS48_RS19130 a85417a1188773b3e821911fa7e1844c 376 Gene3D G3DSA:3.20.20.70 28 375 3.9E-130 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS27820 6875b6f2d39d604bb157ea5bec43e133 338 Gene3D G3DSA:3.40.50.1100 153 338 1.3E-27 T 29-03-2018 CVS48_RS27820 6875b6f2d39d604bb157ea5bec43e133 338 PIRSF PIRSF006278 1 337 1.8E-125 T 29-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CVS48_RS27820 6875b6f2d39d604bb157ea5bec43e133 338 Gene3D G3DSA:3.40.50.1100 50 152 1.6E-34 T 29-03-2018 CVS48_RS27820 6875b6f2d39d604bb157ea5bec43e133 338 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 337 1.7E-184 T 29-03-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 CVS48_RS27820 6875b6f2d39d604bb157ea5bec43e133 338 SUPERFAMILY SSF53686 4 334 3.16E-101 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS27820 6875b6f2d39d604bb157ea5bec43e133 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 12 321 5.2E-48 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS27820 6875b6f2d39d604bb157ea5bec43e133 338 Hamap MF_00807 1-aminocyclopropane-1-carboxylate deaminase [acdS]. 2 338 69.936 T 29-03-2018 IPR020601 1-aminocyclopropane-1-carboxylate deaminase, bacterial GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 CVS48_RS26035 f21ed616dfd570c37d93a72de655646c 470 Pfam PF07690 Major Facilitator Superfamily 32 424 1.9E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS26035 f21ed616dfd570c37d93a72de655646c 470 SUPERFAMILY SSF103473 22 212 4.58E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS26035 f21ed616dfd570c37d93a72de655646c 470 SUPERFAMILY SSF103473 262 468 4.58E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS26035 f21ed616dfd570c37d93a72de655646c 470 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 29 433 3.5E-71 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CVS48_RS26035 f21ed616dfd570c37d93a72de655646c 470 Gene3D G3DSA:1.20.1250.20 22 218 6.1E-29 T 29-03-2018 CVS48_RS26035 f21ed616dfd570c37d93a72de655646c 470 Gene3D G3DSA:1.20.1250.20 266 469 7.3E-22 T 29-03-2018 CVS48_RS09915 2d348d83f8f76368dec99d7511075a28 223 SUPERFAMILY SSF161098 15 203 6.67E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09915 2d348d83f8f76368dec99d7511075a28 223 Gene3D G3DSA:1.10.3720.10 14 218 6.7E-37 T 29-03-2018 CVS48_RS09915 2d348d83f8f76368dec99d7511075a28 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 112 5.5E-25 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS09915 2d348d83f8f76368dec99d7511075a28 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 217 8.3E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19245 10494c8b4562f295c52d2e9369de89b4 203 Gene3D G3DSA:3.40.30.10 1 95 9.0E-28 T 29-03-2018 CVS48_RS19245 10494c8b4562f295c52d2e9369de89b4 203 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 71 3.0E-12 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS19245 10494c8b4562f295c52d2e9369de89b4 203 Gene3D G3DSA:1.20.1050.10 96 191 5.4E-22 T 29-03-2018 CVS48_RS19245 10494c8b4562f295c52d2e9369de89b4 203 SUPERFAMILY SSF47616 75 199 1.2E-24 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS19245 10494c8b4562f295c52d2e9369de89b4 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 115 190 4.4E-9 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CVS48_RS19245 10494c8b4562f295c52d2e9369de89b4 203 SUPERFAMILY SSF52833 1 80 2.52E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS01565 5bc0021fb239b78b2759ca4b13c18ea9 514 Gene3D G3DSA:3.40.920.10 7 218 9.5E-37 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CVS48_RS01565 5bc0021fb239b78b2759ca4b13c18ea9 514 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 20 211 2.0E-15 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CVS48_RS01565 5bc0021fb239b78b2759ca4b13c18ea9 514 SUPERFAMILY SSF53323 12 233 5.75E-9 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CVS48_RS18335 d7ff626c8117da131991653671e8597d 717 Gene3D G3DSA:3.30.420.40 7 114 1.4E-5 T 29-03-2018 CVS48_RS18335 d7ff626c8117da131991653671e8597d 717 Pfam PF01968 Hydantoinase/oxoprolinase 212 506 1.8E-76 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CVS48_RS18335 d7ff626c8117da131991653671e8597d 717 SUPERFAMILY SSF53067 15 89 1.73E-7 T 29-03-2018 CVS48_RS18335 d7ff626c8117da131991653671e8597d 717 SUPERFAMILY SSF53067 270 354 1.73E-7 T 29-03-2018 CVS48_RS18335 d7ff626c8117da131991653671e8597d 717 SUPERFAMILY SSF53067 405 502 1.73E-7 T 29-03-2018 CVS48_RS18335 d7ff626c8117da131991653671e8597d 717 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 15 190 5.6E-51 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CVS48_RS18335 d7ff626c8117da131991653671e8597d 717 Gene3D G3DSA:3.30.420.150 271 550 2.9E-4 T 29-03-2018 CVS48_RS23055 9ee44ade553c175277cd40c7f5c1b0c6 119 PIRSF PIRSF007028 2 119 8.6E-43 T 29-03-2018 IPR009874 Protein of unknown function DUF1428 CVS48_RS23055 9ee44ade553c175277cd40c7f5c1b0c6 119 SUPERFAMILY SSF54909 3 117 1.98E-36 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS23055 9ee44ade553c175277cd40c7f5c1b0c6 119 Gene3D G3DSA:3.30.70.100 1 119 4.3E-43 T 29-03-2018 CVS48_RS23055 9ee44ade553c175277cd40c7f5c1b0c6 119 Pfam PF07237 Protein of unknown function (DUF1428) 3 97 1.9E-33 T 29-03-2018 IPR009874 Protein of unknown function DUF1428 CVS48_RS19720 24b5405f36c3e581322c269b90de665e 177 Gene3D G3DSA:3.40.50.1110 1 177 1.8E-34 T 29-03-2018 CVS48_RS19720 24b5405f36c3e581322c269b90de665e 177 SUPERFAMILY SSF52266 1 176 2.44E-46 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CVS48_RS19720 24b5405f36c3e581322c269b90de665e 177 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 1 159 1.5E-24 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CVS48_RS14940 f9adb386984825baae898ea740236257 473 Pfam PF13533 Biotin-lipoyl like 100 139 4.5E-8 T 29-03-2018 CVS48_RS14940 f9adb386984825baae898ea740236257 473 Gene3D G3DSA:1.20.1600.10 160 426 5.1E-18 T 29-03-2018 CVS48_RS14940 f9adb386984825baae898ea740236257 473 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 60 473 6.7E-121 T 29-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 CVS48_RS14940 f9adb386984825baae898ea740236257 473 SUPERFAMILY SSF111369 92 164 2.35E-5 T 29-03-2018 CVS48_RS14940 f9adb386984825baae898ea740236257 473 Gene3D G3DSA:3.90.1170.30 27 152 6.6E-4 T 29-03-2018 CVS48_RS14940 f9adb386984825baae898ea740236257 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 372 396 2.5E-46 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CVS48_RS14940 f9adb386984825baae898ea740236257 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 339 360 2.5E-46 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CVS48_RS14940 f9adb386984825baae898ea740236257 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 437 452 2.5E-46 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CVS48_RS14940 f9adb386984825baae898ea740236257 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 70 93 2.5E-46 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CVS48_RS14940 f9adb386984825baae898ea740236257 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 396 419 2.5E-46 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CVS48_RS14940 f9adb386984825baae898ea740236257 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 452 472 2.5E-46 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CVS48_RS14940 f9adb386984825baae898ea740236257 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 112 132 2.5E-46 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CVS48_RS14940 f9adb386984825baae898ea740236257 473 Pfam PF13437 HlyD family secretion protein 327 437 3.9E-17 T 29-03-2018 CVS48_RS14940 f9adb386984825baae898ea740236257 473 ProSitePatterns PS00543 HlyD family secretion proteins signature. 437 459 - T 29-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 CVS48_RS13825 20ef16d8f8ec863eac2be5b9334ec104 441 SUPERFAMILY SSF53850 22 315 1.24E-47 T 29-03-2018 CVS48_RS13825 20ef16d8f8ec863eac2be5b9334ec104 441 Gene3D G3DSA:3.40.190.10 16 140 5.7E-11 T 29-03-2018 CVS48_RS13825 20ef16d8f8ec863eac2be5b9334ec104 441 Pfam PF13343 Bacterial extracellular solute-binding protein 75 282 3.0E-21 T 29-03-2018 CVS48_RS13825 20ef16d8f8ec863eac2be5b9334ec104 441 Gene3D G3DSA:3.40.190.10 141 286 1.0E-22 T 29-03-2018 CVS48_RS28725 bff16b0f3726c275d427f7f292184b2e 146 Gene3D G3DSA:3.40.50.720 2 139 5.5E-16 T 29-03-2018 CVS48_RS28725 bff16b0f3726c275d427f7f292184b2e 146 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 120 9.8E-9 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CVS48_RS28725 bff16b0f3726c275d427f7f292184b2e 146 SUPERFAMILY SSF51735 4 123 1.24E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS12965 056613458dff453f1727e7e8c2145adc 340 Pfam PF02562 PhoH-like protein 130 333 4.4E-95 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CVS48_RS12965 056613458dff453f1727e7e8c2145adc 340 SUPERFAMILY SSF52540 129 308 2.01E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS12965 056613458dff453f1727e7e8c2145adc 340 Gene3D G3DSA:3.40.50.300 126 333 6.3E-30 T 29-03-2018 CVS48_RS11100 b0b02cc93273bb64295ad551901ab706 511 SMART SM00858 15 84 1.5E-16 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS11100 b0b02cc93273bb64295ad551901ab706 511 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 109 509 1.6E-161 T 29-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CVS48_RS11100 b0b02cc93273bb64295ad551901ab706 511 Pfam PF08666 SAF domain 15 84 1.2E-14 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS15580 6884088d7f935479b936968ab2d23767 234 Gene3D G3DSA:3.40.50.1860 127 232 1.6E-21 T 29-03-2018 CVS48_RS15580 6884088d7f935479b936968ab2d23767 234 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 195 205 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS15580 6884088d7f935479b936968ab2d23767 234 SUPERFAMILY SSF53681 7 119 2.29E-16 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS15580 6884088d7f935479b936968ab2d23767 234 SUPERFAMILY SSF53681 121 230 1.57E-26 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS15580 6884088d7f935479b936968ab2d23767 234 Gene3D G3DSA:3.40.50.1860 5 126 9.3E-17 T 29-03-2018 CVS48_RS15580 6884088d7f935479b936968ab2d23767 234 TIGRFAM TIGR00035 asp_race: aspartate racemase 40 232 9.6E-31 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CVS48_RS15580 6884088d7f935479b936968ab2d23767 234 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 226 1.1E-37 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 Gene3D G3DSA:3.40.190.10 78 174 8.6E-20 T 29-03-2018 CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 Gene3D G3DSA:3.40.190.10 175 258 6.5E-17 T 29-03-2018 CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 SUPERFAMILY SSF46785 2 102 4.19E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 31 1.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 10 21 1.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 1.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 Pfam PF03466 LysR substrate binding domain 84 287 2.9E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 53 1.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 SUPERFAMILY SSF53850 84 288 3.62E-37 T 29-03-2018 CVS48_RS11250 470e9ca3f5a27ce758081934bf8b7caa 297 Gene3D G3DSA:1.10.10.10 1 77 5.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21110 f9e925f381e2f04e001fe7459fa05ac6 304 Pfam PF04909 Amidohydrolase 38 302 1.9E-33 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS21110 f9e925f381e2f04e001fe7459fa05ac6 304 SUPERFAMILY SSF51556 32 303 1.41E-64 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS21110 f9e925f381e2f04e001fe7459fa05ac6 304 Gene3D G3DSA:3.20.20.140 12 304 7.8E-37 T 29-03-2018 CVS48_RS05490 17378fe6d126b2b30efd0a06e9002a09 355 Gene3D G3DSA:3.60.15.10 17 289 3.9E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS05490 17378fe6d126b2b30efd0a06e9002a09 355 SMART SM00849 42 267 1.2E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS05490 17378fe6d126b2b30efd0a06e9002a09 355 Pfam PF00753 Metallo-beta-lactamase superfamily 42 267 9.8E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS05490 17378fe6d126b2b30efd0a06e9002a09 355 SUPERFAMILY SSF56281 15 352 1.83E-68 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS01245 8c551829474f4527bad4024f4d15a9c7 382 Pfam PF00108 Thiolase, N-terminal domain 10 178 1.0E-8 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CVS48_RS01245 8c551829474f4527bad4024f4d15a9c7 382 SUPERFAMILY SSF53901 7 225 1.01E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01245 8c551829474f4527bad4024f4d15a9c7 382 Gene3D G3DSA:3.40.47.10 1 219 3.5E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01245 8c551829474f4527bad4024f4d15a9c7 382 Gene3D G3DSA:3.40.47.10 220 367 1.1E-11 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS01245 8c551829474f4527bad4024f4d15a9c7 382 PIRSF PIRSF000429 1 377 1.5E-26 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CVS48_RS01245 8c551829474f4527bad4024f4d15a9c7 382 SUPERFAMILY SSF53901 227 354 1.54E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS20305 1ea1a4434c69b171850db6b880a2515f 401 Gene3D G3DSA:2.40.50.100 172 211 4.7E-7 T 29-03-2018 CVS48_RS20305 1ea1a4434c69b171850db6b880a2515f 401 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 294 2.6E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS20305 1ea1a4434c69b171850db6b880a2515f 401 Gene3D G3DSA:2.40.50.100 68 121 7.4E-15 T 29-03-2018 CVS48_RS20305 1ea1a4434c69b171850db6b880a2515f 401 Gene3D G3DSA:1.10.287.470 122 171 2.3E-12 T 29-03-2018 CVS48_RS20305 1ea1a4434c69b171850db6b880a2515f 401 SUPERFAMILY SSF111369 57 301 1.44E-75 T 29-03-2018 CVS48_RS20305 1ea1a4434c69b171850db6b880a2515f 401 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 43 376 7.1E-82 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS23445 ddc94b1ee97dfd0611e68c03504145a1 335 Gene3D G3DSA:1.10.540.10 2 101 2.2E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS23445 ddc94b1ee97dfd0611e68c03504145a1 335 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 188 312 5.3E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS23445 ddc94b1ee97dfd0611e68c03504145a1 335 Gene3D G3DSA:1.20.140.10 184 326 1.0E-18 T 29-03-2018 CVS48_RS23445 ddc94b1ee97dfd0611e68c03504145a1 335 SUPERFAMILY SSF47203 189 318 2.09E-25 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS23445 ddc94b1ee97dfd0611e68c03504145a1 335 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 92 3.3E-5 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS23445 ddc94b1ee97dfd0611e68c03504145a1 335 SUPERFAMILY SSF56645 5 93 5.07E-9 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS21885 db5fe9bb5a86636dedff30336169d6f3 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 314 6.4E-72 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21885 db5fe9bb5a86636dedff30336169d6f3 323 Gene3D G3DSA:3.40.190.10 34 142 0.15 T 29-03-2018 CVS48_RS21885 db5fe9bb5a86636dedff30336169d6f3 323 Gene3D G3DSA:3.40.190.10 143 296 2.8E-13 T 29-03-2018 CVS48_RS21885 db5fe9bb5a86636dedff30336169d6f3 323 PIRSF PIRSF017082 1 323 8.0E-79 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21885 db5fe9bb5a86636dedff30336169d6f3 323 SUPERFAMILY SSF53850 112 286 4.34E-14 T 29-03-2018 CVS48_RS22045 0e2e82c7c426187a5b6edfddb799503d 395 Gene3D G3DSA:1.20.1250.20 1 194 1.3E-11 T 29-03-2018 CVS48_RS22045 0e2e82c7c426187a5b6edfddb799503d 395 Gene3D G3DSA:1.20.1250.20 205 394 5.1E-13 T 29-03-2018 CVS48_RS22045 0e2e82c7c426187a5b6edfddb799503d 395 SUPERFAMILY SSF103473 13 388 1.29E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS22045 0e2e82c7c426187a5b6edfddb799503d 395 Pfam PF07690 Major Facilitator Superfamily 233 383 2.5E-9 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS03370 f1b1de8ebf25bfa1d878535edb6ec4f2 202 Gene3D G3DSA:3.40.50.850 2 200 9.6E-40 T 29-03-2018 CVS48_RS03370 f1b1de8ebf25bfa1d878535edb6ec4f2 202 SUPERFAMILY SSF52499 3 195 2.09E-44 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS03370 f1b1de8ebf25bfa1d878535edb6ec4f2 202 Pfam PF00857 Isochorismatase family 5 186 2.4E-36 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS04535 72c45a8e3bdfce7f2f14058553fb9fee 70 Pfam PF06348 Protein of unknown function (DUF1059) 4 53 1.7E-8 T 29-03-2018 IPR009409 Protein of unknown function DUF1059 CVS48_RS00225 201da1f693646703f62cee7d36587dd1 335 SMART SM00382 38 243 6.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS00225 201da1f693646703f62cee7d36587dd1 335 SUPERFAMILY SSF52540 9 264 5.33E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00225 201da1f693646703f62cee7d36587dd1 335 Gene3D G3DSA:3.40.50.300 6 334 4.5E-73 T 29-03-2018 CVS48_RS00225 201da1f693646703f62cee7d36587dd1 335 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS00225 201da1f693646703f62cee7d36587dd1 335 Pfam PF00005 ABC transporter 30 193 8.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS00225 201da1f693646703f62cee7d36587dd1 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 330 3.2E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS00225 201da1f693646703f62cee7d36587dd1 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 311 8.5E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS20310 7dff5778cd6e6b56034741541c19501b 195 ProSitePatterns PS00356 LacI-type HTH domain signature. 26 44 - T 29-03-2018 CVS48_RS20310 7dff5778cd6e6b56034741541c19501b 195 SUPERFAMILY SSF48498 81 157 6.23E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS20310 7dff5778cd6e6b56034741541c19501b 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 53 1.9E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS20310 7dff5778cd6e6b56034741541c19501b 195 Gene3D G3DSA:1.10.10.60 8 51 1.1E-6 T 29-03-2018 CVS48_RS20310 7dff5778cd6e6b56034741541c19501b 195 SUPERFAMILY SSF46689 23 80 2.86E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS20310 7dff5778cd6e6b56034741541c19501b 195 Gene3D G3DSA:1.10.357.10 52 186 1.4E-11 T 29-03-2018 CVS48_RS04890 5038bca46ecfe4a9f856810072b00502 352 Pfam PF00534 Glycosyl transferases group 1 172 326 1.3E-23 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS04890 5038bca46ecfe4a9f856810072b00502 352 SUPERFAMILY SSF53756 2 348 1.3E-56 T 29-03-2018 CVS48_RS04890 5038bca46ecfe4a9f856810072b00502 352 Gene3D G3DSA:3.40.50.2000 1 156 5.5E-12 T 29-03-2018 CVS48_RS04890 5038bca46ecfe4a9f856810072b00502 352 Pfam PF13439 Glycosyltransferase Family 4 13 151 3.2E-12 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS04890 5038bca46ecfe4a9f856810072b00502 352 Gene3D G3DSA:3.40.50.2000 157 333 1.7E-30 T 29-03-2018 CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 SUPERFAMILY SSF47384 92 173 1.28E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 SMART SM00387 221 329 1.9E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 222 326 3.7E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 274 284 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 256 270 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 Gene3D G3DSA:3.30.565.10 181 332 1.9E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 SMART SM00388 109 174 5.0E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 Gene3D G3DSA:1.10.287.130 99 170 5.6E-11 T 29-03-2018 CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 SUPERFAMILY SSF55874 164 326 1.44E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS26390 bad6fca1947ba9c459f74b0fb7a462d2 341 Pfam PF00512 His Kinase A (phospho-acceptor) domain 109 172 3.2E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS26330 8a6659d5c38379a031b3316ea88c038c 239 SMART SM00895 90 213 2.9E-15 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS26330 8a6659d5c38379a031b3316ea88c038c 239 SMART SM00345 22 80 1.5E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS26330 8a6659d5c38379a031b3316ea88c038c 239 Gene3D G3DSA:1.10.10.10 2 76 8.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26330 8a6659d5c38379a031b3316ea88c038c 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 2.5E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS26330 8a6659d5c38379a031b3316ea88c038c 239 SUPERFAMILY SSF46785 13 106 7.92E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26330 8a6659d5c38379a031b3316ea88c038c 239 Pfam PF07729 FCD domain 90 212 1.4E-19 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS26330 8a6659d5c38379a031b3316ea88c038c 239 SUPERFAMILY SSF48008 86 217 4.18E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS26330 8a6659d5c38379a031b3316ea88c038c 239 Gene3D G3DSA:1.20.120.530 77 228 3.2E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS10715 50aa4312ef6c483cba73ce27d3158f99 375 SUPERFAMILY SSF53756 22 371 7.22E-70 T 29-03-2018 CVS48_RS10715 50aa4312ef6c483cba73ce27d3158f99 375 Pfam PF00534 Glycosyl transferases group 1 186 350 7.2E-31 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS10715 50aa4312ef6c483cba73ce27d3158f99 375 Gene3D G3DSA:3.40.50.2000 16 193 7.4E-18 T 29-03-2018 CVS48_RS10715 50aa4312ef6c483cba73ce27d3158f99 375 Pfam PF13477 Glycosyl transferase 4-like 5 154 2.7E-25 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS10715 50aa4312ef6c483cba73ce27d3158f99 375 Gene3D G3DSA:3.40.50.2000 194 365 5.1E-41 T 29-03-2018 CVS48_RS27240 9d0b8fe83f6140ccbf44628064fca5f4 225 SUPERFAMILY SSF102712 124 200 3.27E-5 T 29-03-2018 CVS48_RS27240 9d0b8fe83f6140ccbf44628064fca5f4 225 Gene3D G3DSA:1.10.150.20 8 88 1.4E-5 T 29-03-2018 CVS48_RS27240 9d0b8fe83f6140ccbf44628064fca5f4 225 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CVS48_RS27240 9d0b8fe83f6140ccbf44628064fca5f4 225 Gene3D G3DSA:3.40.140.10 100 225 7.2E-42 T 29-03-2018 CVS48_RS27240 9d0b8fe83f6140ccbf44628064fca5f4 225 Pfam PF04002 RadC-like JAB domain 105 222 2.4E-41 T 29-03-2018 IPR025657 RadC-like JAB domain CVS48_RS27240 9d0b8fe83f6140ccbf44628064fca5f4 225 SUPERFAMILY SSF47781 16 89 8.9E-12 T 29-03-2018 IPR010994 RuvA domain 2-like CVS48_RS27240 9d0b8fe83f6140ccbf44628064fca5f4 225 TIGRFAM TIGR00608 radc: DNA repair protein RadC 12 223 1.3E-66 T 29-03-2018 IPR001405 RadC protein CVS48_RS10505 5b322e3e5a5eebff5e693d14488ad106 147 SUPERFAMILY SSF88723 4 138 3.64E-25 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS10505 5b322e3e5a5eebff5e693d14488ad106 147 Gene3D G3DSA:3.40.50.1010 3 140 1.8E-22 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS10505 5b322e3e5a5eebff5e693d14488ad106 147 Pfam PF01850 PIN domain 4 124 1.8E-13 T 29-03-2018 IPR002716 PIN domain CVS48_RS00695 f5c34d7a06e0d8cf50de69b80a023374 77 TIGRFAM TIGR03758 conj_TIGR03758: integrating conjugative element protein, PFL_4701 family 2 77 7.7E-32 T 29-03-2018 IPR021676 Protein of unknown function DUF3262 CVS48_RS00695 f5c34d7a06e0d8cf50de69b80a023374 77 Pfam PF11660 Protein of unknown function (DUF3262) 1 76 5.8E-26 T 29-03-2018 IPR021676 Protein of unknown function DUF3262 CVS48_RS26710 aea35f6bf0c7cb3aa61e5a6ded960667 153 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 15 145 4.9E-32 T 29-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein CVS48_RS26710 aea35f6bf0c7cb3aa61e5a6ded960667 153 Gene3D G3DSA:3.40.1230.10 1 150 4.6E-36 T 29-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein CVS48_RS26710 aea35f6bf0c7cb3aa61e5a6ded960667 153 SUPERFAMILY SSF64076 13 147 1.57E-30 T 29-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein CVS48_RS26370 64420b65960fc2709ffa012be2722a7b 271 Pfam PF04909 Amidohydrolase 6 270 7.0E-42 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS26370 64420b65960fc2709ffa012be2722a7b 271 SUPERFAMILY SSF51556 1 270 5.61E-74 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS26370 64420b65960fc2709ffa012be2722a7b 271 Gene3D G3DSA:3.20.20.140 1 271 5.3E-39 T 29-03-2018 CVS48_RS05935 40678aa68bfc9e608985d509f0dfabec 264 SUPERFAMILY SSF161098 7 253 1.44E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05935 40678aa68bfc9e608985d509f0dfabec 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 253 7.9E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05935 40678aa68bfc9e608985d509f0dfabec 264 Gene3D G3DSA:1.10.3720.10 6 256 8.3E-42 T 29-03-2018 CVS48_RS19165 bfdd62a32c05da4bf84f3b1d5f855c87 290 Pfam PF02666 Phosphatidylserine decarboxylase 65 284 2.2E-61 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CVS48_RS19165 bfdd62a32c05da4bf84f3b1d5f855c87 290 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 53 284 4.2E-76 T 29-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CVS48_RS19165 bfdd62a32c05da4bf84f3b1d5f855c87 290 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 12 287 47.34 T 29-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CVS48_RS07840 6a66a0ba91368c48dc7923ff65ea3f89 178 Pfam PF09335 SNARE associated Golgi protein 56 167 5.9E-12 T 29-03-2018 IPR032816 SNARE associated Golgi protein CVS48_RS18495 647ff58831c60b2cf0317ebc25969bee 376 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 359 7.2E-62 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS18495 647ff58831c60b2cf0317ebc25969bee 376 Gene3D G3DSA:3.90.1170.30 8 113 4.8E-4 T 29-03-2018 CVS48_RS18495 647ff58831c60b2cf0317ebc25969bee 376 SUPERFAMILY SSF111369 54 265 4.58E-20 T 29-03-2018 CVS48_RS18495 647ff58831c60b2cf0317ebc25969bee 376 Gene3D G3DSA:1.10.287.470 114 163 1.8E-8 T 29-03-2018 CVS48_RS18495 647ff58831c60b2cf0317ebc25969bee 376 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 265 9.4E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS18495 647ff58831c60b2cf0317ebc25969bee 376 Gene3D G3DSA:2.40.50.100 166 366 4.1E-7 T 29-03-2018 CVS48_RS05175 d76595afb40cc1311346565c503ba949 148 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 7 148 22.032 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CVS48_RS05175 d76595afb40cc1311346565c503ba949 148 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 10 24 2.9E-8 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CVS48_RS05175 d76595afb40cc1311346565c503ba949 148 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 109 118 2.9E-8 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CVS48_RS05175 d76595afb40cc1311346565c503ba949 148 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 100 108 2.9E-8 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CVS48_RS05175 d76595afb40cc1311346565c503ba949 148 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 7 147 2.9E-41 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CVS48_RS05175 d76595afb40cc1311346565c503ba949 148 SUPERFAMILY SSF81330 17 143 9.29E-32 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CVS48_RS05175 d76595afb40cc1311346565c503ba949 148 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 7 147 4.1E-35 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 Gene3D G3DSA:3.20.20.140 10 260 6.0E-35 T 29-03-2018 CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 11 1033 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 SMART SM00481 12 79 1.9E-23 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 Gene3D G3DSA:2.40.50.140 980 1076 3.6E-14 T 29-03-2018 CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 295 736 3.4E-175 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 Pfam PF14579 Helix-hairpin-helix motif 809 907 1.8E-27 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 Pfam PF01336 OB-fold nucleic acid binding domain 999 1074 6.2E-11 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 Pfam PF02811 PHP domain 13 177 1.5E-42 T 29-03-2018 IPR004013 PHP domain GO:0003824 CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 SUPERFAMILY SSF89550 11 267 1.61E-10 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CVS48_RS26170 a6f0fd1307701358bf8ddf01bba4be14 1163 Gene3D G3DSA:1.10.150.280 839 904 4.6E-8 T 29-03-2018 CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 133 150 8.2E-9 T 29-03-2018 CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 171 191 8.2E-9 T 29-03-2018 CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 151 170 8.2E-9 T 29-03-2018 CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 Gene3D G3DSA:3.30.1330.60 64 193 5.7E-46 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 Pfam PF00691 OmpA family 87 182 8.2E-27 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 ProSitePatterns PS01068 OmpA-like domain. 120 164 - T 29-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 PRINTS PR01021 OMPA domain signature 88 110 4.2E-23 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 PRINTS PR01021 OMPA domain signature 118 133 4.2E-23 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 PRINTS PR01021 OMPA domain signature 133 149 4.2E-23 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS27535 350a51c2544ff4340e4e1725baa27e7e 193 SUPERFAMILY SSF103088 79 188 4.45E-41 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS19625 75527a5cae8b3af292b5c285299917e9 166 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 154 3.3E-22 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 SUPERFAMILY SSF52821 9 128 2.1E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 SMART SM00450 381 474 0.74 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 SMART SM00450 138 237 2.3E-7 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 SMART SM00450 276 372 3.8E-6 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 SMART SM00450 14 113 2.3E-13 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 SUPERFAMILY SSF52821 264 368 4.71E-23 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 Gene3D G3DSA:3.40.250.10 259 378 3.9E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 Gene3D G3DSA:3.40.250.10 379 477 6.5E-8 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 Gene3D G3DSA:3.40.250.10 9 119 4.5E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 Gene3D G3DSA:3.40.250.10 122 248 2.7E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 SUPERFAMILY SSF52821 115 243 5.76E-29 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 SUPERFAMILY SSF52821 380 526 5.76E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 Pfam PF00581 Rhodanese-like domain 17 109 1.1E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 Pfam PF00581 Rhodanese-like domain 142 233 9.7E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS06195 a68ee687537eff07d73d3c8620a2c7b6 532 Pfam PF00581 Rhodanese-like domain 290 365 4.5E-7 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS23775 e7c0d514e158dedf6d1666593160649d 320 Gene3D G3DSA:3.40.50.720 6 167 1.4E-15 T 29-03-2018 CVS48_RS23775 e7c0d514e158dedf6d1666593160649d 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 239 1.3E-78 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS23775 e7c0d514e158dedf6d1666593160649d 320 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 5 307 47.921 T 29-03-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 CVS48_RS23775 e7c0d514e158dedf6d1666593160649d 320 SUPERFAMILY SSF51735 5 308 1.24E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23775 e7c0d514e158dedf6d1666593160649d 320 Gene3D G3DSA:3.90.25.10 168 317 5.9E-44 T 29-03-2018 CVS48_RS11520 6e455624dedee7935f238eecc6d4516a 482 Gene3D G3DSA:3.40.720.10 1 367 2.0E-68 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS11520 6e455624dedee7935f238eecc6d4516a 482 Gene3D G3DSA:3.30.1120.10 370 454 3.8E-14 T 29-03-2018 CVS48_RS11520 6e455624dedee7935f238eecc6d4516a 482 SUPERFAMILY SSF53649 2 437 4.65E-103 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS11520 6e455624dedee7935f238eecc6d4516a 482 Pfam PF00884 Sulfatase 4 343 1.7E-51 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CVS48_RS01145 7891e6d3c0fe46957d37199295bdea05 253 SUPERFAMILY SSF52402 25 246 1.54E-19 T 29-03-2018 CVS48_RS01145 7891e6d3c0fe46957d37199295bdea05 253 Pfam PF01012 Electron transfer flavoprotein domain 24 161 1.6E-14 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS01145 7891e6d3c0fe46957d37199295bdea05 253 Gene3D G3DSA:3.40.50.620 17 253 9.6E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS14650 ddde4976435c2bb3d4633d6bbcdef7e0 251 Gene3D G3DSA:3.40.190.10 147 251 5.8E-16 T 29-03-2018 CVS48_RS14650 ddde4976435c2bb3d4633d6bbcdef7e0 251 SMART SM00062 25 250 5.5E-46 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS14650 ddde4976435c2bb3d4633d6bbcdef7e0 251 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 247 6.7E-57 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS14650 ddde4976435c2bb3d4633d6bbcdef7e0 251 SUPERFAMILY SSF53850 1 248 5.44E-61 T 29-03-2018 CVS48_RS14650 ddde4976435c2bb3d4633d6bbcdef7e0 251 SMART SM00079 25 250 0.0019 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CVS48_RS14650 ddde4976435c2bb3d4633d6bbcdef7e0 251 Gene3D G3DSA:3.40.190.10 20 146 1.2E-30 T 29-03-2018 CVS48_RS19035 7035e471a08deb6d52ecff16683a0fdb 62 Gene3D G3DSA:1.10.1470.10 1 62 8.5E-19 T 29-03-2018 IPR008462 CsbD-like domain CVS48_RS19035 7035e471a08deb6d52ecff16683a0fdb 62 SUPERFAMILY SSF69047 1 59 4.32E-16 T 29-03-2018 IPR008462 CsbD-like domain CVS48_RS19035 7035e471a08deb6d52ecff16683a0fdb 62 Pfam PF05532 CsbD-like 4 56 4.7E-17 T 29-03-2018 IPR008462 CsbD-like domain CVS48_RS22375 1cf97ffb636c145144f8cc1bc1d38ad6 381 Pfam PF13458 Periplasmic binding protein 28 369 6.5E-60 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS22375 1cf97ffb636c145144f8cc1bc1d38ad6 381 SUPERFAMILY SSF53822 27 374 8.88E-93 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS22375 1cf97ffb636c145144f8cc1bc1d38ad6 381 Gene3D G3DSA:3.40.50.2300 11 190 1.9E-39 T 29-03-2018 CVS48_RS22375 1cf97ffb636c145144f8cc1bc1d38ad6 381 Gene3D G3DSA:3.40.50.2300 191 355 2.7E-21 T 29-03-2018 CVS48_RS10840 2e1f598df184690ad04bad0dc54dcad7 528 ProSitePatterns PS01303 BCCT family of transporters signature. 331 340 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CVS48_RS10840 2e1f598df184690ad04bad0dc54dcad7 528 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 29 516 1.2E-160 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CVS48_RS10840 2e1f598df184690ad04bad0dc54dcad7 528 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 67 516 8.2E-142 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CVS48_RS05860 72cbc6749c8cf8221a69781713d96695 266 Gene3D G3DSA:1.10.3720.10 8 256 2.8E-42 T 29-03-2018 CVS48_RS05860 72cbc6749c8cf8221a69781713d96695 266 SUPERFAMILY SSF161098 10 254 4.39E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05860 72cbc6749c8cf8221a69781713d96695 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 251 1.3E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19680 1dadc0ec21025189549fa116311c11e6 396 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 79 6.1E-37 T 29-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS19680 1dadc0ec21025189549fa116311c11e6 396 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 316 4.9E-105 T 29-03-2018 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS19680 1dadc0ec21025189549fa116311c11e6 396 Pfam PF07055 Enoyl reductase FAD binding domain 323 386 4.3E-29 T 29-03-2018 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS19680 1dadc0ec21025189549fa116311c11e6 396 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 392 53.08 T 29-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS12975 babbb1ca35000d2cd6c67c6e551bc2b2 255 SUPERFAMILY SSF48317 29 240 2.09E-30 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS12975 babbb1ca35000d2cd6c67c6e551bc2b2 255 Gene3D G3DSA:1.20.144.10 31 236 1.8E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS12975 babbb1ca35000d2cd6c67c6e551bc2b2 255 SMART SM00014 120 233 2.3E-8 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS12975 babbb1ca35000d2cd6c67c6e551bc2b2 255 Pfam PF01569 PAP2 superfamily 121 230 8.8E-19 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS28415 17f9c2e50862028587831144a268562a 774 SUPERFAMILY SSF81301 215 393 3.43E-62 T 29-03-2018 CVS48_RS28415 17f9c2e50862028587831144a268562a 774 Gene3D G3DSA:3.30.70.260 697 774 2.4E-13 T 29-03-2018 CVS48_RS28415 17f9c2e50862028587831144a268562a 774 Pfam PF04607 Region found in RelA / SpoT proteins 258 367 1.9E-37 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CVS48_RS28415 17f9c2e50862028587831144a268562a 774 SUPERFAMILY SSF81271 446 508 1.29E-18 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CVS48_RS28415 17f9c2e50862028587831144a268562a 774 SUPERFAMILY SSF55021 698 772 4.28E-14 T 29-03-2018 CVS48_RS28415 17f9c2e50862028587831144a268562a 774 Gene3D G3DSA:3.30.460.10 215 348 1.7E-44 T 29-03-2018 CVS48_RS28415 17f9c2e50862028587831144a268562a 774 Gene3D G3DSA:3.10.20.30 444 517 1.1E-21 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS28415 17f9c2e50862028587831144a268562a 774 Pfam PF13328 HD domain 36 199 9.2E-49 T 29-03-2018 IPR003607 HD/PDEase domain CVS48_RS28415 17f9c2e50862028587831144a268562a 774 Pfam PF13291 ACT domain 698 773 4.2E-15 T 29-03-2018 IPR002912 ACT domain CVS48_RS28415 17f9c2e50862028587831144a268562a 774 SUPERFAMILY SSF109604 15 213 8.16E-43 T 29-03-2018 CVS48_RS28415 17f9c2e50862028587831144a268562a 774 SMART SM00954 258 368 2.4E-63 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CVS48_RS28415 17f9c2e50862028587831144a268562a 774 Pfam PF02824 TGS domain 449 507 9.6E-21 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CVS48_RS04525 9b6bff83820c827fb719386aea36d8c6 368 Gene3D G3DSA:3.40.50.300 8 77 1.1E-11 T 29-03-2018 CVS48_RS04525 9b6bff83820c827fb719386aea36d8c6 368 Pfam PF05128 Domain of unknown function (DUF697) 221 362 4.0E-7 T 29-03-2018 IPR021147 Protein of unknown function DUF697 CVS48_RS04525 9b6bff83820c827fb719386aea36d8c6 368 Gene3D G3DSA:3.40.50.300 78 239 6.7E-10 T 29-03-2018 CVS48_RS04525 9b6bff83820c827fb719386aea36d8c6 368 SUPERFAMILY SSF52540 26 164 3.43E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04525 9b6bff83820c827fb719386aea36d8c6 368 Pfam PF01926 50S ribosome-binding GTPase 30 150 9.7E-14 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS19690 a79552355b1c0d5814ecccc60b72748f 241 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 23 235 1.1E-56 T 29-03-2018 CVS48_RS19690 a79552355b1c0d5814ecccc60b72748f 241 Pfam PF12710 haloacid dehalogenase-like hydrolase 27 201 2.4E-26 T 29-03-2018 CVS48_RS19690 a79552355b1c0d5814ecccc60b72748f 241 Gene3D G3DSA:1.10.150.210 51 84 1.5E-19 T 29-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CVS48_RS19690 a79552355b1c0d5814ecccc60b72748f 241 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 26 202 2.3E-33 T 29-03-2018 CVS48_RS19690 a79552355b1c0d5814ecccc60b72748f 241 SUPERFAMILY SSF56784 21 232 1.6E-43 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS19690 a79552355b1c0d5814ecccc60b72748f 241 Gene3D G3DSA:3.40.50.1000 85 235 3.9E-24 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS19690 a79552355b1c0d5814ecccc60b72748f 241 Gene3D G3DSA:3.40.50.1000 21 50 0.16 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS11400 423304609d12e016f188129bbcce3597 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 1.4E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS11400 423304609d12e016f188129bbcce3597 233 Gene3D G3DSA:1.10.10.10 122 230 3.3E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11400 423304609d12e016f188129bbcce3597 233 SMART SM00862 147 223 5.7E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS11400 423304609d12e016f188129bbcce3597 233 Pfam PF00072 Response regulator receiver domain 5 113 1.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS11400 423304609d12e016f188129bbcce3597 233 SUPERFAMILY SSF46894 123 224 5.95E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS11400 423304609d12e016f188129bbcce3597 233 Gene3D G3DSA:3.40.50.2300 1 121 7.8E-35 T 29-03-2018 CVS48_RS11400 423304609d12e016f188129bbcce3597 233 SUPERFAMILY SSF52172 2 126 1.34E-37 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS11400 423304609d12e016f188129bbcce3597 233 SMART SM00448 2 112 3.1E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS03750 28937fce38676549809c531549e0ac8a 232 Pfam PF00072 Response regulator receiver domain 5 117 7.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS03750 28937fce38676549809c531549e0ac8a 232 SUPERFAMILY SSF46894 123 226 2.83E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS03750 28937fce38676549809c531549e0ac8a 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 1.5E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS03750 28937fce38676549809c531549e0ac8a 232 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 4.9E-113 T 29-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 CVS48_RS03750 28937fce38676549809c531549e0ac8a 232 SMART SM00448 3 116 2.2E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS03750 28937fce38676549809c531549e0ac8a 232 SMART SM00862 148 225 2.3E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS03750 28937fce38676549809c531549e0ac8a 232 SUPERFAMILY SSF52172 3 126 6.97E-43 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS03750 28937fce38676549809c531549e0ac8a 232 Gene3D G3DSA:1.10.10.10 125 230 2.3E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03750 28937fce38676549809c531549e0ac8a 232 Gene3D G3DSA:3.40.50.2300 3 124 1.4E-35 T 29-03-2018 CVS48_RS23175 3fd585fd3d8b6a35b86c3a461f77f339 339 Pfam PF00122 E1-E2 ATPase 165 239 1.6E-10 T 29-03-2018 CVS48_RS23175 3fd585fd3d8b6a35b86c3a461f77f339 339 Gene3D G3DSA:1.20.1110.10 99 244 7.0E-10 T 29-03-2018 CVS48_RS10735 7a1da6d835b97402a262797bdcb7f044 471 SUPERFAMILY SSF56176 3 215 3.27E-75 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS10735 7a1da6d835b97402a262797bdcb7f044 471 Gene3D G3DSA:1.10.45.10 429 468 2.0E-16 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CVS48_RS10735 7a1da6d835b97402a262797bdcb7f044 471 Pfam PF01565 FAD binding domain 38 175 3.0E-35 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS10735 7a1da6d835b97402a262797bdcb7f044 471 Gene3D G3DSA:3.30.465.10 94 214 6.1E-38 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS10735 7a1da6d835b97402a262797bdcb7f044 471 SUPERFAMILY SSF55103 218 469 1.96E-56 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS10735 7a1da6d835b97402a262797bdcb7f044 471 Gene3D G3DSA:3.30.43.10 1 93 3.8E-23 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS10735 7a1da6d835b97402a262797bdcb7f044 471 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 468 1.0E-51 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS15865 9c3a8f9b97c4ba575c16fdb3425f9613 346 SUPERFAMILY SSF102198 95 118 5.62E-13 T 29-03-2018 CVS48_RS15865 9c3a8f9b97c4ba575c16fdb3425f9613 346 SUPERFAMILY SSF102198 167 345 5.62E-13 T 29-03-2018 CVS48_RS15865 9c3a8f9b97c4ba575c16fdb3425f9613 346 Gene3D G3DSA:3.50.30.50 41 346 1.4E-46 T 29-03-2018 CVS48_RS15865 9c3a8f9b97c4ba575c16fdb3425f9613 346 Pfam PF04199 Putative cyclase 84 274 5.0E-15 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CVS48_RS09405 ae3928240d7dacc810940986cfc88672 125 Gene3D G3DSA:1.20.59.10 18 123 3.9E-20 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS09405 ae3928240d7dacc810940986cfc88672 125 SMART SM00830 30 113 5.9E-16 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS09405 ae3928240d7dacc810940986cfc88672 125 SUPERFAMILY SSF48600 21 113 1.02E-17 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS09405 ae3928240d7dacc810940986cfc88672 125 Pfam PF01817 Chorismate mutase type II 30 111 2.4E-13 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS21165 da978da156088da2d7c1d5d9a54bde8d 196 Pfam PF04366 Las17-binding protein actin regulator 109 193 8.4E-16 T 29-03-2018 IPR007461 Ysc84 actin-binding domain CVS48_RS21165 da978da156088da2d7c1d5d9a54bde8d 196 Gene3D G3DSA:2.40.128.130 9 194 7.1E-4 T 29-03-2018 CVS48_RS10755 c2cdafd2473856458cee1eb60c40f938 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 9 416 1.7E-100 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS10755 c2cdafd2473856458cee1eb60c40f938 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 422 7.1E-120 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS10755 c2cdafd2473856458cee1eb60c40f938 427 PIRSF PIRSF006066 1 427 5.2E-138 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS26325 42b351e78de97529db779becd0624852 245 Gene3D G3DSA:3.40.50.1860 22 128 0.0038 T 29-03-2018 CVS48_RS26325 42b351e78de97529db779becd0624852 245 Gene3D G3DSA:3.40.50.1860 129 221 1.2E-8 T 29-03-2018 CVS48_RS05940 8b408b23bd75976b0577a45422488194 293 SUPERFAMILY SSF161098 17 288 1.57E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05940 8b408b23bd75976b0577a45422488194 293 Gene3D G3DSA:1.10.3720.10 19 292 3.3E-48 T 29-03-2018 CVS48_RS05940 8b408b23bd75976b0577a45422488194 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 285 3.1E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS02835 fb7c1b8ad507bd6c6d17de926aa3d065 361 Gene3D G3DSA:1.10.287.470 128 167 7.3E-11 T 29-03-2018 CVS48_RS02835 fb7c1b8ad507bd6c6d17de926aa3d065 361 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 277 9.2E-33 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS02835 fb7c1b8ad507bd6c6d17de926aa3d065 361 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 52 356 1.9E-83 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS02835 fb7c1b8ad507bd6c6d17de926aa3d065 361 SUPERFAMILY SSF111369 68 281 3.14E-45 T 29-03-2018 CVS48_RS02835 fb7c1b8ad507bd6c6d17de926aa3d065 361 Gene3D G3DSA:2.40.50.100 76 127 3.5E-14 T 29-03-2018 CVS48_RS02835 fb7c1b8ad507bd6c6d17de926aa3d065 361 Gene3D G3DSA:2.40.50.100 168 343 1.8E-9 T 29-03-2018 CVS48_RS20090 c47d277ee01763082b44cc901e5b115f 160 Pfam PF04073 Aminoacyl-tRNA editing domain 23 148 4.1E-25 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS20090 c47d277ee01763082b44cc901e5b115f 160 SUPERFAMILY SSF55826 3 157 1.44E-34 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS20090 c47d277ee01763082b44cc901e5b115f 160 Gene3D G3DSA:3.90.960.10 1 160 3.0E-36 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS09590 531b4c8362a74ce9067aea1aa30ec959 311 Gene3D G3DSA:3.20.20.70 5 307 6.2E-111 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS09590 531b4c8362a74ce9067aea1aa30ec959 311 Pfam PF05853 beta-keto acid cleavage enzyme 8 303 1.3E-106 T 29-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CVS48_RS02675 3dc06fedb81838f33c5e40a58e50296a 140 SUPERFAMILY SSF54637 10 136 8.92E-42 T 29-03-2018 IPR029069 HotDog domain CVS48_RS02675 3dc06fedb81838f33c5e40a58e50296a 140 Pfam PF03061 Thioesterase superfamily 23 107 5.1E-19 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CVS48_RS02675 3dc06fedb81838f33c5e40a58e50296a 140 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 13 128 2.0E-34 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CVS48_RS02675 3dc06fedb81838f33c5e40a58e50296a 140 Gene3D G3DSA:3.10.129.10 2 140 2.3E-37 T 29-03-2018 CVS48_RS02675 3dc06fedb81838f33c5e40a58e50296a 140 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 11 133 4.5E-51 T 29-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 CVS48_RS02675 3dc06fedb81838f33c5e40a58e50296a 140 PIRSF PIRSF003230 2 140 9.5E-47 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CVS48_RS08755 eeea07f3b5dbcbd9ee47a26edc7a37a1 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 1.0E-34 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS08755 eeea07f3b5dbcbd9ee47a26edc7a37a1 286 Gene3D G3DSA:1.10.3470.10 1 279 2.1E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS08490 ba9b808c7da9f8d1d7c5a8b518098749 1308 Pfam PF14331 ImcF-related N-terminal domain 167 393 2.6E-40 T 29-03-2018 IPR025743 ImcF-related, N-terminal domain CVS48_RS08490 ba9b808c7da9f8d1d7c5a8b518098749 1308 Gene3D G3DSA:1.20.5.1000 966 1159 0.0026 T 29-03-2018 CVS48_RS08490 ba9b808c7da9f8d1d7c5a8b518098749 1308 Gene3D G3DSA:3.30.70.1070 1227 1294 4.9E-4 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 Pfam PF03466 LysR substrate binding domain 103 308 1.7E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 Gene3D G3DSA:3.40.190.10 104 192 5.6E-12 T 29-03-2018 CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 Gene3D G3DSA:3.40.190.10 193 279 9.2E-19 T 29-03-2018 CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 SUPERFAMILY SSF53850 103 309 2.71E-39 T 29-03-2018 CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 SUPERFAMILY SSF46785 21 126 4.94E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 1.5E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 55 1.5E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 55 66 1.5E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 78 1.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04595 6ab54c8a97296e4ad18ea2ef50397eab 315 Gene3D G3DSA:1.10.10.10 18 99 1.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10410 219826c11ef53971de20327124497745 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 212 8.3E-43 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CVS48_RS10410 219826c11ef53971de20327124497745 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 324 2.4E-96 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CVS48_RS00830 884edf5b32244b06f1588bb7f8aa2b70 301 Pfam PF12101 Protein of unknown function (DUF3577) 131 257 1.8E-49 T 29-03-2018 IPR021960 Protein of unknown function DUF3577 CVS48_RS00830 884edf5b32244b06f1588bb7f8aa2b70 301 Pfam PF12101 Protein of unknown function (DUF3577) 5 123 3.1E-37 T 29-03-2018 IPR021960 Protein of unknown function DUF3577 CVS48_RS06990 04f6fb635b07f4e023dc05cf4c9bd6e3 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 4 177 1.3E-84 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CVS48_RS06990 04f6fb635b07f4e023dc05cf4c9bd6e3 181 Gene3D G3DSA:2.60.120.10 1 180 1.4E-77 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS06990 04f6fb635b07f4e023dc05cf4c9bd6e3 181 SUPERFAMILY SSF51182 1 178 2.57E-77 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS06990 04f6fb635b07f4e023dc05cf4c9bd6e3 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 2.0E-78 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CVS48_RS06990 04f6fb635b07f4e023dc05cf4c9bd6e3 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 175 5.0E-74 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 SUPERFAMILY SSF53850 96 300 2.35E-23 T 29-03-2018 CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 Pfam PF03466 LysR substrate binding domain 96 300 1.8E-24 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 2.8E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 Gene3D G3DSA:1.10.10.10 1 87 3.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 Gene3D G3DSA:3.40.190.10 184 268 1.4E-10 T 29-03-2018 CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 SUPERFAMILY SSF46785 6 90 9.25E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20470 e1a68d09f111250d51843dd9f3c74fa7 301 Gene3D G3DSA:3.40.190.10 92 183 1.8E-9 T 29-03-2018 CVS48_RS17910 8f84cd66fe4475ca6fc20c2123f971e4 404 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 393 9.0E-99 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS17910 8f84cd66fe4475ca6fc20c2123f971e4 404 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 10 394 2.9E-120 T 29-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CVS48_RS17910 8f84cd66fe4475ca6fc20c2123f971e4 404 Gene3D G3DSA:3.40.640.10 6 262 2.1E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS17910 8f84cd66fe4475ca6fc20c2123f971e4 404 PIRSF PIRSF001434 1 397 9.6E-122 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS17910 8f84cd66fe4475ca6fc20c2123f971e4 404 Gene3D G3DSA:3.90.1150.10 263 399 9.3E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS17910 8f84cd66fe4475ca6fc20c2123f971e4 404 SUPERFAMILY SSF53383 29 393 4.57E-90 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS03360 7bcca5403317a450f80920040cab98e2 604 Gene3D G3DSA:2.160.20.70 320 439 3.0E-7 T 29-03-2018 CVS48_RS03360 7bcca5403317a450f80920040cab98e2 604 Pfam PF03961 Flagellar Assembly Protein A 145 600 3.6E-113 T 29-03-2018 IPR005646 Flagellar assembly protein A CVS48_RS01645 7c511b6520fbcfbcefaa6e759c553a58 215 Gene3D G3DSA:3.20.20.70 11 215 5.1E-33 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS01645 7c511b6520fbcfbcefaa6e759c553a58 215 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 13 207 1.1E-48 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CVS48_RS01645 7c511b6520fbcfbcefaa6e759c553a58 215 Pfam PF01081 KDPG and KHG aldolase 14 202 2.0E-39 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CVS48_RS01645 7c511b6520fbcfbcefaa6e759c553a58 215 SUPERFAMILY SSF51569 11 209 2.01E-53 T 29-03-2018 CVS48_RS15435 f61c490471ac4581c41bfd7324b12eb6 775 SUPERFAMILY SSF82866 610 772 1.31E-19 T 29-03-2018 CVS48_RS15435 f61c490471ac4581c41bfd7324b12eb6 775 SUPERFAMILY SSF82866 190 404 6.67E-15 T 29-03-2018 CVS48_RS15435 f61c490471ac4581c41bfd7324b12eb6 775 Gene3D G3DSA:1.20.1640.10 594 772 1.4E-19 T 29-03-2018 CVS48_RS15435 f61c490471ac4581c41bfd7324b12eb6 775 Gene3D G3DSA:1.20.1640.10 205 402 1.2E-16 T 29-03-2018 CVS48_RS15435 f61c490471ac4581c41bfd7324b12eb6 775 Pfam PF03176 MMPL family 192 308 1.2E-5 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 5.2E-19 T 29-03-2018 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.2E-19 T 29-03-2018 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 5.2E-19 T 29-03-2018 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 5.2E-19 T 29-03-2018 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 220 236 5.2E-19 T 29-03-2018 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 Gene3D G3DSA:3.50.50.60 147 206 0.003 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 Gene3D G3DSA:3.50.50.60 4 146 3.1E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 5.4E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 5.4E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 174 5.4E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 SUPERFAMILY SSF51905 1 119 4.08E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 SUPERFAMILY SSF51905 223 294 4.08E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 Gene3D G3DSA:3.40.50.720 207 300 5.5E-11 T 29-03-2018 CVS48_RS04185 b547572b34c3fd138ea94088978be5e0 300 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 273 5.3E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01640 dac85a3873c1cb6d2e2298363d0f84f7 312 SUPERFAMILY SSF53613 6 307 3.7E-79 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS01640 dac85a3873c1cb6d2e2298363d0f84f7 312 Gene3D G3DSA:3.40.1190.20 2 310 2.3E-64 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS01640 dac85a3873c1cb6d2e2298363d0f84f7 312 Pfam PF00294 pfkB family carbohydrate kinase 7 298 1.6E-55 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CVS48_RS09595 ef61397ffcb99e1a6b7ab127b9c95c0f 93 SUPERFAMILY SSF54534 4 92 4.09E-29 T 29-03-2018 CVS48_RS09595 ef61397ffcb99e1a6b7ab127b9c95c0f 93 Pfam PF13616 PPIC-type PPIASE domain 4 91 1.5E-24 T 29-03-2018 CVS48_RS09595 ef61397ffcb99e1a6b7ab127b9c95c0f 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CVS48_RS09595 ef61397ffcb99e1a6b7ab127b9c95c0f 93 Gene3D G3DSA:3.10.50.40 1 93 1.9E-33 T 29-03-2018 CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 7 384 37.835 T 29-03-2018 IPR017687 Outer membrane protein assembly factor BamB CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 Gene3D G3DSA:2.140.10.10 275 385 1.9E-9 T 29-03-2018 CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 SMART SM00564 67 98 21.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 SMART SM00564 280 312 570.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 SMART SM00564 190 222 760.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 SMART SM00564 106 137 18.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 SMART SM00564 146 177 0.005 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 SMART SM00564 322 353 1.3 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 11 381 4.4E-128 T 29-03-2018 IPR017687 Outer membrane protein assembly factor BamB CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 Gene3D G3DSA:2.140.10.10 27 184 6.5E-25 T 29-03-2018 CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 Gene3D G3DSA:2.140.10.10 185 274 3.3E-7 T 29-03-2018 CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 SUPERFAMILY SSF50998 29 374 1.57E-69 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CVS48_RS14710 969e0ee656a259d110dd42f64f4fb7aa 385 Pfam PF13360 PQQ-like domain 80 309 8.1E-48 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CVS48_RS01280 b4a922b4691b27346629b224ebc3a9ae 257 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 34 226 5.7E-54 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 CVS48_RS01280 b4a922b4691b27346629b224ebc3a9ae 257 SUPERFAMILY SSF55729 4 232 3.39E-86 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS01280 b4a922b4691b27346629b224ebc3a9ae 257 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 35 213 6.2E-70 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 CVS48_RS01280 b4a922b4691b27346629b224ebc3a9ae 257 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 257 94.651 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 CVS48_RS13545 4cf1b3ca170a845cd8424d215f127f0a 147 SUPERFAMILY SSF54637 3 141 4.67E-35 T 29-03-2018 IPR029069 HotDog domain CVS48_RS13545 4cf1b3ca170a845cd8424d215f127f0a 147 Pfam PF01575 MaoC like domain 15 108 6.3E-18 T 29-03-2018 IPR002539 MaoC-like domain CVS48_RS13545 4cf1b3ca170a845cd8424d215f127f0a 147 Gene3D G3DSA:3.10.129.10 1 144 2.3E-31 T 29-03-2018 CVS48_RS23830 d69b471dd547202b76d1df177a99e495 534 Gene3D G3DSA:2.115.10.20 124 531 1.1E-14 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CVS48_RS23830 d69b471dd547202b76d1df177a99e495 534 SUPERFAMILY SSF75005 294 461 4.97E-13 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CVS48_RS20435 33a71c031b37a835336c9e3bb252cc86 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 136 12.45 T 29-03-2018 IPR022907 VapC family GO:0004540 CVS48_RS20435 33a71c031b37a835336c9e3bb252cc86 144 Pfam PF01850 PIN domain 2 123 5.8E-17 T 29-03-2018 IPR002716 PIN domain CVS48_RS20435 33a71c031b37a835336c9e3bb252cc86 144 SUPERFAMILY SSF88723 1 137 1.93E-29 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS20435 33a71c031b37a835336c9e3bb252cc86 144 Gene3D G3DSA:3.40.50.1010 1 139 9.8E-25 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS22275 c24e4b6fb65294b2c4d2432990c722b0 255 SMART SM00346 1 91 0.0042 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS22275 c24e4b6fb65294b2c4d2432990c722b0 255 SUPERFAMILY SSF55781 75 248 3.47E-30 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS22275 c24e4b6fb65294b2c4d2432990c722b0 255 Pfam PF01614 Bacterial transcriptional regulator 125 237 8.0E-6 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS22275 c24e4b6fb65294b2c4d2432990c722b0 255 Pfam PF09339 IclR helix-turn-helix domain 10 54 1.5E-9 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS22275 c24e4b6fb65294b2c4d2432990c722b0 255 Gene3D G3DSA:1.10.10.10 1 74 2.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22275 c24e4b6fb65294b2c4d2432990c722b0 255 SUPERFAMILY SSF46785 4 67 1.36E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22275 c24e4b6fb65294b2c4d2432990c722b0 255 Gene3D G3DSA:3.30.450.40 77 252 3.0E-28 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 SUPERFAMILY SSF53732 13 587 1.96E-189 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 Gene3D G3DSA:3.30.499.10 2 227 1.5E-59 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 Pfam PF00694 Aconitase C-terminal domain 657 788 1.1E-30 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 SUPERFAMILY SSF52016 599 858 1.18E-68 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 860 0.0 T 29-03-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 Gene3D G3DSA:3.30.499.10 360 547 9.1E-55 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 Gene3D G3DSA:3.20.19.10 621 860 5.4E-69 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 PRINTS PR00415 Aconitase family signature 162 170 2.1E-30 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 PRINTS PR00415 Aconitase family signature 191 204 2.1E-30 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 PRINTS PR00415 Aconitase family signature 402 413 2.1E-30 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 PRINTS PR00415 Aconitase family signature 360 374 2.1E-30 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 PRINTS PR00415 Aconitase family signature 464 477 2.1E-30 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 PRINTS PR00415 Aconitase family signature 138 151 2.1E-30 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 PRINTS PR00415 Aconitase family signature 267 280 2.1E-30 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 PRINTS PR00415 Aconitase family signature 205 220 2.1E-30 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 PRINTS PR00415 Aconitase family signature 281 294 2.1E-30 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 Pfam PF00330 Aconitase family (aconitate hydratase) 70 533 4.0E-149 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS10145 72617c19f5e324b959e15cc5cefeba9a 872 Gene3D G3DSA:3.40.1060.10 228 359 2.9E-42 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS23795 590cfbc6465b77c69fd4e9558d2c49a1 375 Pfam PF13439 Glycosyltransferase Family 4 13 179 1.4E-19 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS23795 590cfbc6465b77c69fd4e9558d2c49a1 375 Gene3D G3DSA:3.40.50.2000 189 352 4.7E-34 T 29-03-2018 CVS48_RS23795 590cfbc6465b77c69fd4e9558d2c49a1 375 Gene3D G3DSA:3.40.50.2000 2 188 5.3E-13 T 29-03-2018 CVS48_RS23795 590cfbc6465b77c69fd4e9558d2c49a1 375 SUPERFAMILY SSF53756 4 367 1.64E-68 T 29-03-2018 CVS48_RS23795 590cfbc6465b77c69fd4e9558d2c49a1 375 Pfam PF00534 Glycosyl transferases group 1 197 349 2.3E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS08485 bd385c59d83cb97f3cb566f5831080f3 288 Pfam PF00589 Phage integrase family 95 263 2.3E-38 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS08485 bd385c59d83cb97f3cb566f5831080f3 288 Gene3D G3DSA:1.10.443.10 101 280 1.3E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CVS48_RS08485 bd385c59d83cb97f3cb566f5831080f3 288 Gene3D G3DSA:1.10.150.130 4 100 9.2E-6 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CVS48_RS08485 bd385c59d83cb97f3cb566f5831080f3 288 SUPERFAMILY SSF56349 20 271 4.12E-55 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 Gene3D G3DSA:3.40.50.720 1 44 6.7E-11 T 29-03-2018 CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 Gene3D G3DSA:3.40.50.720 45 250 6.6E-65 T 29-03-2018 CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 3.8E-68 T 29-03-2018 CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 SUPERFAMILY SSF51735 5 250 1.66E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS10240 b1a02db157944fdf6cea7a83a17700e0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS28365 91f8367a74a87fb1f92de88a964db568 320 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 7 320 53.677 T 29-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 CVS48_RS28365 91f8367a74a87fb1f92de88a964db568 320 SUPERFAMILY SSF56524 67 316 2.09E-89 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CVS48_RS28365 91f8367a74a87fb1f92de88a964db568 320 Pfam PF00174 Oxidoreductase molybdopterin binding domain 99 254 4.9E-29 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CVS48_RS28365 91f8367a74a87fb1f92de88a964db568 320 Gene3D G3DSA:3.90.420.10 58 320 7.8E-57 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CVS48_RS27780 49b7d2252aebc973e5c87756204efa8e 838 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 171 837 1.5E-129 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS27780 49b7d2252aebc973e5c87756204efa8e 838 Gene3D G3DSA:2.170.130.10 130 277 7.2E-32 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS27780 49b7d2252aebc973e5c87756204efa8e 838 Pfam PF00593 TonB dependent receptor 343 837 2.0E-66 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS27780 49b7d2252aebc973e5c87756204efa8e 838 Pfam PF07715 TonB-dependent Receptor Plug Domain 170 270 5.7E-23 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS27780 49b7d2252aebc973e5c87756204efa8e 838 SUPERFAMILY SSF56935 146 838 1.74E-144 T 29-03-2018 CVS48_RS27780 49b7d2252aebc973e5c87756204efa8e 838 SMART SM00965 75 126 3.7E-14 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS27780 49b7d2252aebc973e5c87756204efa8e 838 Pfam PF07660 Secretin and TonB N terminus short domain 77 125 3.4E-7 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS27780 49b7d2252aebc973e5c87756204efa8e 838 Gene3D G3DSA:2.40.170.20 283 838 1.8E-93 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS20180 429f9a60aefffc3b605dbcbf6aefbd64 325 SUPERFAMILY SSF53850 106 287 8.87E-12 T 29-03-2018 CVS48_RS20180 429f9a60aefffc3b605dbcbf6aefbd64 325 Gene3D G3DSA:3.40.190.10 125 234 2.0E-8 T 29-03-2018 CVS48_RS20180 429f9a60aefffc3b605dbcbf6aefbd64 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 316 5.7E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS20180 429f9a60aefffc3b605dbcbf6aefbd64 325 PIRSF PIRSF017082 1 324 3.1E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS28190 da8ac2f2e8612abec778200fc7df9242 405 Pfam PF13458 Periplasmic binding protein 29 368 2.7E-90 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS28190 da8ac2f2e8612abec778200fc7df9242 405 Gene3D G3DSA:3.40.50.2300 208 361 3.2E-13 T 29-03-2018 CVS48_RS28190 da8ac2f2e8612abec778200fc7df9242 405 Gene3D G3DSA:3.40.50.2300 27 207 3.0E-25 T 29-03-2018 CVS48_RS28190 da8ac2f2e8612abec778200fc7df9242 405 SUPERFAMILY SSF53822 29 403 4.37E-87 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS13625 6e7170a55c49c6a0bccd7ce5add9b0fa 312 SUPERFAMILY SSF51569 7 308 2.62E-66 T 29-03-2018 CVS48_RS13625 6e7170a55c49c6a0bccd7ce5add9b0fa 312 Pfam PF00701 Dihydrodipicolinate synthetase family 7 304 9.4E-37 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS13625 6e7170a55c49c6a0bccd7ce5add9b0fa 312 PIRSF PIRSF001365 3 312 3.0E-54 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS13625 6e7170a55c49c6a0bccd7ce5add9b0fa 312 SMART SM01130 6 308 3.1E-68 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS13625 6e7170a55c49c6a0bccd7ce5add9b0fa 312 Gene3D G3DSA:3.20.20.70 2 310 1.0E-68 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS19340 849991d86a01178324802f82c9a1cb69 443 Gene3D G3DSA:3.40.640.10 100 338 7.9E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS19340 849991d86a01178324802f82c9a1cb69 443 Pfam PF00155 Aminotransferase class I and II 97 433 1.6E-51 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS19340 849991d86a01178324802f82c9a1cb69 443 SUPERFAMILY SSF53383 76 441 2.42E-102 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS19340 849991d86a01178324802f82c9a1cb69 443 Gene3D G3DSA:3.90.1150.10 339 443 3.1E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS12060 960bb86fe968b0ffc74f973c8bcac576 428 Gene3D G3DSA:3.90.1530.10 61 253 1.2E-43 T 29-03-2018 CVS48_RS12060 960bb86fe968b0ffc74f973c8bcac576 428 SUPERFAMILY SSF110849 166 331 5.75E-48 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CVS48_RS12060 960bb86fe968b0ffc74f973c8bcac576 428 SUPERFAMILY SSF110849 63 127 5.75E-48 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CVS48_RS12060 960bb86fe968b0ffc74f973c8bcac576 428 Pfam PF08857 Putative ParB-like nuclease 67 294 4.9E-52 T 29-03-2018 IPR014956 Putative ParB-like nuclease CVS48_RS12060 960bb86fe968b0ffc74f973c8bcac576 428 Gene3D G3DSA:1.10.8.10 263 348 9.2E-14 T 29-03-2018 CVS48_RS16645 66d7e7cc22c707bf213293b701dea555 83 Pfam PF04226 Transglycosylase associated protein 33 80 9.5E-17 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CVS48_RS28470 9003b55cda28d1761cb4a4512d23d732 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS28470 9003b55cda28d1761cb4a4512d23d732 236 SMART SM00382 30 215 9.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS28470 9003b55cda28d1761cb4a4512d23d732 236 SUPERFAMILY SSF52540 4 229 2.21E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28470 9003b55cda28d1761cb4a4512d23d732 236 Pfam PF00005 ABC transporter 21 163 4.7E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28470 9003b55cda28d1761cb4a4512d23d732 236 Gene3D G3DSA:3.40.50.300 1 235 2.1E-48 T 29-03-2018 CVS48_RS00160 f3bdb3bf177517fea6613a580ef67d40 296 SUPERFAMILY SSF53850 88 289 3.5E-36 T 29-03-2018 CVS48_RS00160 f3bdb3bf177517fea6613a580ef67d40 296 Gene3D G3DSA:3.40.190.10 179 260 4.8E-18 T 29-03-2018 CVS48_RS00160 f3bdb3bf177517fea6613a580ef67d40 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 8.3E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS00160 f3bdb3bf177517fea6613a580ef67d40 296 Gene3D G3DSA:3.40.190.10 78 178 1.1E-17 T 29-03-2018 CVS48_RS00160 f3bdb3bf177517fea6613a580ef67d40 296 Pfam PF03466 LysR substrate binding domain 87 286 2.0E-40 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS00160 f3bdb3bf177517fea6613a580ef67d40 296 SUPERFAMILY SSF46785 2 109 2.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00160 f3bdb3bf177517fea6613a580ef67d40 296 Gene3D G3DSA:1.10.10.10 1 77 1.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12675 791d35d451ba8c8ab83c23a6839c8e82 423 Pfam PF00872 Transposase, Mutator family 37 391 1.8E-120 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS12675 791d35d451ba8c8ab83c23a6839c8e82 423 ProSitePatterns PS01007 Transposases, Mutator family, signature. 251 275 - T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS03265 791d35d451ba8c8ab83c23a6839c8e82 423 Pfam PF00872 Transposase, Mutator family 37 391 1.8E-120 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS03265 791d35d451ba8c8ab83c23a6839c8e82 423 ProSitePatterns PS01007 Transposases, Mutator family, signature. 251 275 - T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS09475 791d35d451ba8c8ab83c23a6839c8e82 423 Pfam PF00872 Transposase, Mutator family 37 391 1.8E-120 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS09475 791d35d451ba8c8ab83c23a6839c8e82 423 ProSitePatterns PS01007 Transposases, Mutator family, signature. 251 275 - T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CVS48_RS22270 947c319a676b0859452d18acc3e05b45 234 Pfam PF03575 Peptidase family S51 3 208 4.1E-54 T 29-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CVS48_RS22270 947c319a676b0859452d18acc3e05b45 234 Gene3D G3DSA:3.40.50.880 1 229 1.7E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS22270 947c319a676b0859452d18acc3e05b45 234 SUPERFAMILY SSF52317 3 220 9.16E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS12100 2e38bb6663bd881d88a68ee7c3874e2d 213 Pfam PF00510 Cytochrome c oxidase subunit III 30 210 1.4E-12 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12100 2e38bb6663bd881d88a68ee7c3874e2d 213 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 33 212 8.0E-83 T 29-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 CVS48_RS12100 2e38bb6663bd881d88a68ee7c3874e2d 213 Gene3D G3DSA:1.20.120.80 27 212 3.4E-51 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12100 2e38bb6663bd881d88a68ee7c3874e2d 213 SUPERFAMILY SSF81452 18 210 2.09E-59 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 PIRSF PIRSF037495 2 461 9.1E-144 T 29-03-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.9E-6 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 292 310 1.9E-6 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 1.9E-6 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 Gene3D G3DSA:3.50.50.60 257 357 6.3E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 307 6.9E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 3.3E-10 T 29-03-2018 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 3.3E-10 T 29-03-2018 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.3E-10 T 29-03-2018 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 Pfam PF04324 BFD-like [2Fe-2S] binding domain 372 424 1.3E-12 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 Gene3D G3DSA:3.50.50.60 6 107 1.6E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 Gene3D G3DSA:3.50.50.60 108 255 6.7E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05925 348d7c2afb7ea2c588d9c2bc6a50fd0d 461 SUPERFAMILY SSF51905 7 326 1.73E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS26495 b321643b24cb0938baedd948340a53bd 467 Gene3D G3DSA:3.30.870.10 49 270 2.4E-34 T 29-03-2018 CVS48_RS26495 b321643b24cb0938baedd948340a53bd 467 Pfam PF13091 PLD-like domain 308 434 6.4E-28 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS26495 b321643b24cb0938baedd948340a53bd 467 Pfam PF13091 PLD-like domain 91 200 1.1E-13 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CVS48_RS26495 b321643b24cb0938baedd948340a53bd 467 Gene3D G3DSA:3.30.870.10 301 450 1.4E-30 T 29-03-2018 CVS48_RS26495 b321643b24cb0938baedd948340a53bd 467 SMART SM00155 380 407 1.2E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS26495 b321643b24cb0938baedd948340a53bd 467 SMART SM00155 175 202 0.029 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CVS48_RS26495 b321643b24cb0938baedd948340a53bd 467 SUPERFAMILY SSF56024 63 205 6.59E-46 T 29-03-2018 CVS48_RS26495 b321643b24cb0938baedd948340a53bd 467 SUPERFAMILY SSF56024 238 297 6.59E-46 T 29-03-2018 CVS48_RS26495 b321643b24cb0938baedd948340a53bd 467 SUPERFAMILY SSF56024 264 449 3.14E-43 T 29-03-2018 CVS48_RS11360 f5d236c24ceda41085c8fe98c55cdead 143 SUPERFAMILY SSF55298 12 140 3.46E-33 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS11360 f5d236c24ceda41085c8fe98c55cdead 143 Pfam PF01042 Endoribonuclease L-PSP 16 138 1.0E-26 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS11360 f5d236c24ceda41085c8fe98c55cdead 143 Gene3D G3DSA:3.30.1330.40 4 142 6.2E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS21785 d03737b74947c1298bdf3b21daab8022 272 SUPERFAMILY SSF51556 2 260 2.21E-68 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS21785 d03737b74947c1298bdf3b21daab8022 272 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CVS48_RS21785 d03737b74947c1298bdf3b21daab8022 272 PIRSF PIRSF005902 1 263 2.4E-56 T 29-03-2018 IPR001130 TatD family GO:0016788 CVS48_RS21785 d03737b74947c1298bdf3b21daab8022 272 Pfam PF01026 TatD related DNase 3 259 2.5E-57 T 29-03-2018 IPR001130 TatD family GO:0016788 CVS48_RS21785 d03737b74947c1298bdf3b21daab8022 272 Gene3D G3DSA:3.20.20.140 1 266 2.0E-63 T 29-03-2018 CVS48_RS28580 8cdf42c2823e72195af9523b6318d4a6 435 Pfam PF00583 Acetyltransferase (GNAT) family 306 400 2.2E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS28580 8cdf42c2823e72195af9523b6318d4a6 435 Gene3D G3DSA:3.30.420.40 1 145 2.3E-36 T 29-03-2018 CVS48_RS28580 8cdf42c2823e72195af9523b6318d4a6 435 SUPERFAMILY SSF55729 286 426 3.84E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS28580 8cdf42c2823e72195af9523b6318d4a6 435 SUPERFAMILY SSF53067 5 108 7.77E-21 T 29-03-2018 CVS48_RS28580 8cdf42c2823e72195af9523b6318d4a6 435 Gene3D G3DSA:3.40.630.30 285 434 1.5E-32 T 29-03-2018 CVS48_RS28580 8cdf42c2823e72195af9523b6318d4a6 435 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 5 240 2.5E-56 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CVS48_RS28580 8cdf42c2823e72195af9523b6318d4a6 435 Pfam PF00814 Glycoprotease family 37 136 4.9E-24 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS28580 8cdf42c2823e72195af9523b6318d4a6 435 SUPERFAMILY SSF53067 115 238 9.71E-14 T 29-03-2018 CVS48_RS28580 8cdf42c2823e72195af9523b6318d4a6 435 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 291 423 2.0E-29 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 SMART SM00448 8 119 1.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 Gene3D G3DSA:3.40.50.2300 2 130 1.4E-32 T 29-03-2018 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 Gene3D G3DSA:1.10.10.10 131 204 7.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 SUPERFAMILY SSF52172 9 158 6.55E-37 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 SUPERFAMILY SSF46894 138 200 2.55E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 Pfam PF00072 Response regulator receiver domain 10 119 7.9E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 5.5E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS16670 9c07b8f165363cdb7a1ad8529daf3c44 208 SMART SM00421 143 200 2.3E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS07285 c11478f413f9a1fcf846d875cc0f0e9c 390 Pfam PF03824 High-affinity nickel-transport protein 86 383 1.2E-57 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CVS48_RS22660 de3d3611e54703fe18d7de7c0f2cf4c4 337 Pfam PF02424 ApbE family 23 302 6.5E-82 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CVS48_RS22660 de3d3611e54703fe18d7de7c0f2cf4c4 337 PIRSF PIRSF006268 7 320 2.2E-87 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CVS48_RS22660 de3d3611e54703fe18d7de7c0f2cf4c4 337 SUPERFAMILY SSF143631 18 322 7.32E-97 T 29-03-2018 IPR003374 ApbE-like domain CVS48_RS22660 de3d3611e54703fe18d7de7c0f2cf4c4 337 Gene3D G3DSA:3.10.520.10 26 319 8.0E-57 T 29-03-2018 CVS48_RS02215 7cdb9e42c629d5de6419872641e5918a 533 SUPERFAMILY SSF141322 457 519 6.93E-10 T 29-03-2018 CVS48_RS02215 7cdb9e42c629d5de6419872641e5918a 533 Gene3D G3DSA:2.40.50.140 454 523 8.0E-15 T 29-03-2018 CVS48_RS02215 7cdb9e42c629d5de6419872641e5918a 533 Pfam PF01957 NfeD-like C-terminal, partner-binding 384 520 6.3E-32 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain CVS48_RS02215 7cdb9e42c629d5de6419872641e5918a 533 Gene3D G3DSA:3.90.226.10 51 307 2.7E-26 T 29-03-2018 CVS48_RS02215 7cdb9e42c629d5de6419872641e5918a 533 SUPERFAMILY SSF52096 225 284 1.65E-26 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS02215 7cdb9e42c629d5de6419872641e5918a 533 SUPERFAMILY SSF52096 62 167 1.65E-26 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS20875 9d52684cd4698909a29c24d67a6b1a2a 329 Pfam PF00892 EamA-like transporter family 31 163 6.8E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS20875 9d52684cd4698909a29c24d67a6b1a2a 329 Pfam PF00892 EamA-like transporter family 177 309 1.3E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS20875 9d52684cd4698909a29c24d67a6b1a2a 329 SUPERFAMILY SSF103481 65 166 5.23E-12 T 29-03-2018 CVS48_RS20875 9d52684cd4698909a29c24d67a6b1a2a 329 SUPERFAMILY SSF103481 210 314 1.83E-9 T 29-03-2018 CVS48_RS20555 bfc955461ce859d2a9c13930e345e3f0 623 Gene3D G3DSA:3.20.20.70 350 560 2.1E-22 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS20555 bfc955461ce859d2a9c13930e345e3f0 623 Gene3D G3DSA:3.40.50.280 23 279 2.2E-8 T 29-03-2018 CVS48_RS20555 bfc955461ce859d2a9c13930e345e3f0 623 SMART SM00729 349 562 9.7E-13 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CVS48_RS20555 bfc955461ce859d2a9c13930e345e3f0 623 Pfam PF04055 Radical SAM superfamily 352 513 1.4E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CVS48_RS20555 bfc955461ce859d2a9c13930e345e3f0 623 SUPERFAMILY SSF102114 326 517 3.34E-25 T 29-03-2018 CVS48_RS19615 199f1e079116c7f4218df7cbeb4e93c0 256 Gene3D G3DSA:3.90.79.10 125 251 6.4E-32 T 29-03-2018 CVS48_RS19615 199f1e079116c7f4218df7cbeb4e93c0 256 ProSitePatterns PS00893 Nudix box signature. 158 179 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CVS48_RS19615 199f1e079116c7f4218df7cbeb4e93c0 256 SUPERFAMILY SSF55811 77 236 5.42E-42 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS19615 199f1e079116c7f4218df7cbeb4e93c0 256 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 92 119 3.1E-9 T 29-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CVS48_RS19615 199f1e079116c7f4218df7cbeb4e93c0 256 Pfam PF00293 NUDIX domain 129 230 2.6E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CVS48_RS19615 199f1e079116c7f4218df7cbeb4e93c0 256 SUPERFAMILY SSF55811 3 95 6.69E-8 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS19615 199f1e079116c7f4218df7cbeb4e93c0 256 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 43 90 6.9E-6 T 29-03-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 195 2.1E-5 T 29-03-2018 CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.2E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.2E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.2E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 Gene3D G3DSA:3.40.50.720 162 242 2.3E-23 T 29-03-2018 CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 6 242 1.2E-115 T 29-03-2018 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 Gene3D G3DSA:3.40.50.720 4 161 3.6E-43 T 29-03-2018 CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 242 2.3E-54 T 29-03-2018 CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 SUPERFAMILY SSF51735 6 242 1.09E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15410 010589a4c7894290085db04158eacf9a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS08765 293c201c9ff94e17bba72d8154f62dd7 137 Gene3D G3DSA:1.20.1290.10 17 137 7.0E-35 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS08765 293c201c9ff94e17bba72d8154f62dd7 137 SUPERFAMILY SSF69118 7 130 2.56E-37 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS08765 293c201c9ff94e17bba72d8154f62dd7 137 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 123 2.9E-21 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS24510 3b02b440add7c986594d7975cd7ce928 120 SMART SM00448 1 113 5.3E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS24510 3b02b440add7c986594d7975cd7ce928 120 Gene3D G3DSA:3.40.50.2300 1 115 2.6E-20 T 29-03-2018 CVS48_RS24510 3b02b440add7c986594d7975cd7ce928 120 Pfam PF00072 Response regulator receiver domain 3 113 2.8E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS24510 3b02b440add7c986594d7975cd7ce928 120 SUPERFAMILY SSF52172 1 113 3.42E-19 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS27680 ad1d48d03941d0c610bda7ccab4431c1 544 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 47 213 5.3E-65 T 29-03-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 CVS48_RS27680 ad1d48d03941d0c610bda7ccab4431c1 544 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 16 541 1.5E-198 T 29-03-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 CVS48_RS27680 ad1d48d03941d0c610bda7ccab4431c1 544 Gene3D G3DSA:3.40.50.1820 172 512 1.2E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS27680 ad1d48d03941d0c610bda7ccab4431c1 544 SUPERFAMILY SSF53474 159 475 5.28E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21760 ef02468c475907f3fee83625a98f9f0b 314 Gene3D G3DSA:3.40.50.1980 32 152 1.2E-26 T 29-03-2018 CVS48_RS21760 ef02468c475907f3fee83625a98f9f0b 314 SUPERFAMILY SSF53807 30 299 8.24E-65 T 29-03-2018 CVS48_RS21760 ef02468c475907f3fee83625a98f9f0b 314 Gene3D G3DSA:3.40.50.1980 153 314 4.4E-33 T 29-03-2018 CVS48_RS21760 ef02468c475907f3fee83625a98f9f0b 314 Pfam PF01497 Periplasmic binding protein 56 283 1.1E-25 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CVS48_RS03440 56d7c381e4c84ff3f27fc2316ed8ab86 266 Gene3D G3DSA:3.30.70.270 94 265 1.7E-53 T 29-03-2018 CVS48_RS03440 56d7c381e4c84ff3f27fc2316ed8ab86 266 Pfam PF00990 Diguanylate cyclase, GGDEF domain 102 258 3.2E-44 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS03440 56d7c381e4c84ff3f27fc2316ed8ab86 266 SUPERFAMILY SSF55073 106 260 1.8E-47 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS03440 56d7c381e4c84ff3f27fc2316ed8ab86 266 SMART SM00267 90 262 1.6E-60 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS03440 56d7c381e4c84ff3f27fc2316ed8ab86 266 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 98 260 2.5E-49 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS09585 18d19308dbb9a4cce37a8e47b842de8c 399 Gene3D G3DSA:3.40.50.2300 10 164 6.4E-22 T 29-03-2018 CVS48_RS09585 18d19308dbb9a4cce37a8e47b842de8c 399 Gene3D G3DSA:3.40.50.2300 165 307 1.5E-31 T 29-03-2018 CVS48_RS09585 18d19308dbb9a4cce37a8e47b842de8c 399 Pfam PF13458 Periplasmic binding protein 27 362 5.2E-83 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS09585 18d19308dbb9a4cce37a8e47b842de8c 399 SUPERFAMILY SSF53822 27 397 4.71E-84 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS05140 304c2ee42aee29f39c8678ef34a6f924 122 PRINTS PR00332 Histidine triad family signature 98 108 1.9E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CVS48_RS05140 304c2ee42aee29f39c8678ef34a6f924 122 PRINTS PR00332 Histidine triad family signature 27 45 1.9E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CVS48_RS05140 304c2ee42aee29f39c8678ef34a6f924 122 PRINTS PR00332 Histidine triad family signature 6 22 1.9E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CVS48_RS05140 304c2ee42aee29f39c8678ef34a6f924 122 ProSitePatterns PS00892 HIT domain signature. 91 109 - T 29-03-2018 IPR019808 Histidine triad, conserved site CVS48_RS05140 304c2ee42aee29f39c8678ef34a6f924 122 SUPERFAMILY SSF54197 1 112 1.18E-39 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CVS48_RS05140 304c2ee42aee29f39c8678ef34a6f924 122 Gene3D G3DSA:3.30.428.10 1 115 3.0E-36 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CVS48_RS05140 304c2ee42aee29f39c8678ef34a6f924 122 Pfam PF01230 HIT domain 13 111 5.1E-26 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CVS48_RS11460 b18920cc9a4bacee1d63ab55a833991f 349 SUPERFAMILY SSF53474 56 345 6.43E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11460 b18920cc9a4bacee1d63ab55a833991f 349 Gene3D G3DSA:3.40.50.1820 52 349 2.9E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11460 b18920cc9a4bacee1d63ab55a833991f 349 Pfam PF00561 alpha/beta hydrolase fold 80 209 1.4E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS11460 b18920cc9a4bacee1d63ab55a833991f 349 PRINTS PR00412 Epoxide hydrolase signature 165 178 1.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS11460 b18920cc9a4bacee1d63ab55a833991f 349 PRINTS PR00412 Epoxide hydrolase signature 83 101 1.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS11460 b18920cc9a4bacee1d63ab55a833991f 349 PRINTS PR00412 Epoxide hydrolase signature 151 164 1.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS11460 b18920cc9a4bacee1d63ab55a833991f 349 PRINTS PR00412 Epoxide hydrolase signature 324 346 1.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS11460 b18920cc9a4bacee1d63ab55a833991f 349 PRINTS PR00412 Epoxide hydrolase signature 103 118 1.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS11460 b18920cc9a4bacee1d63ab55a833991f 349 PRINTS PR00412 Epoxide hydrolase signature 290 306 1.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CVS48_RS21850 91a3d5fc08738a5fb05a6c98f21326c7 393 Pfam PF13458 Periplasmic binding protein 37 367 3.2E-62 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS21850 91a3d5fc08738a5fb05a6c98f21326c7 393 Gene3D G3DSA:3.40.50.2300 18 156 8.7E-17 T 29-03-2018 CVS48_RS21850 91a3d5fc08738a5fb05a6c98f21326c7 393 Gene3D G3DSA:3.40.50.2300 157 332 7.3E-23 T 29-03-2018 CVS48_RS21850 91a3d5fc08738a5fb05a6c98f21326c7 393 SUPERFAMILY SSF53822 33 385 3.06E-63 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 Gene3D G3DSA:3.30.70.120 1 108 2.4E-49 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 SMART SM00938 4 105 3.6E-68 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 PIRSF PIRSF039144 1 112 2.3E-54 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 7.1E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 SUPERFAMILY SSF54913 2 112 6.35E-45 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 PRINTS PR00340 P-II protein signature 23 41 8.4E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 PRINTS PR00340 P-II protein signature 52 75 8.4E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 PRINTS PR00340 P-II protein signature 83 103 8.4E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS16130 6b0cd1af685ad09cd62dc06e93cd17d5 112 PRINTS PR00340 P-II protein signature 2 17 8.4E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CVS48_RS06325 80b406501f22bb50dd83c5e0802475b6 156 Gene3D G3DSA:1.10.455.10 6 156 2.5E-58 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CVS48_RS06325 80b406501f22bb50dd83c5e0802475b6 156 PIRSF PIRSF002122 3 156 2.7E-58 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CVS48_RS06325 80b406501f22bb50dd83c5e0802475b6 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06325 80b406501f22bb50dd83c5e0802475b6 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.7E-66 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CVS48_RS06325 80b406501f22bb50dd83c5e0802475b6 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.494 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CVS48_RS06325 80b406501f22bb50dd83c5e0802475b6 156 SUPERFAMILY SSF47973 2 149 1.2E-60 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CVS48_RS06325 80b406501f22bb50dd83c5e0802475b6 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 5.1E-66 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CVS48_RS08010 96458e92453d7a86e86894455e45b86c 116 Gene3D G3DSA:3.40.250.10 6 116 5.0E-29 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS08010 96458e92453d7a86e86894455e45b86c 116 SUPERFAMILY SSF52821 11 114 1.83E-32 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS08010 96458e92453d7a86e86894455e45b86c 116 SMART SM00450 16 111 1.7E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS08010 96458e92453d7a86e86894455e45b86c 116 Pfam PF00581 Rhodanese-like domain 18 108 1.8E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS04720 e5921ffd17b2ff74235b72543b9c1b6d 385 Gene3D G3DSA:3.10.560.10 165 249 5.6E-11 T 29-03-2018 CVS48_RS04720 e5921ffd17b2ff74235b72543b9c1b6d 385 Gene3D G3DSA:3.10.560.10 250 345 7.4E-9 T 29-03-2018 CVS48_RS04720 e5921ffd17b2ff74235b72543b9c1b6d 385 Pfam PF02563 Polysaccharide biosynthesis/export protein 85 164 6.7E-13 T 29-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 CVS48_RS04720 e5921ffd17b2ff74235b72543b9c1b6d 385 Gene3D G3DSA:3.30.1950.10 88 164 5.2E-11 T 29-03-2018 CVS48_RS04795 c20f5cbc3e66dcb8a964235722ec3628 230 Pfam PF00005 ABC transporter 18 159 8.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS04795 c20f5cbc3e66dcb8a964235722ec3628 230 SUPERFAMILY SSF52540 3 219 2.98E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04795 c20f5cbc3e66dcb8a964235722ec3628 230 Gene3D G3DSA:3.40.50.300 1 230 1.6E-53 T 29-03-2018 CVS48_RS04795 c20f5cbc3e66dcb8a964235722ec3628 230 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 3 230 1.2E-100 T 29-03-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE CVS48_RS04795 c20f5cbc3e66dcb8a964235722ec3628 230 SMART SM00382 26 209 3.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS08420 0a3a2b1713d8ac429a140d40e618157c 339 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 54 294 8.8E-7 T 29-03-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 CVS48_RS08785 a5855087977544961aa8664a94a6ae85 409 SUPERFAMILY SSF103473 5 408 7.98E-79 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS08785 a5855087977544961aa8664a94a6ae85 409 Pfam PF07690 Major Facilitator Superfamily 23 301 5.1E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS08785 a5855087977544961aa8664a94a6ae85 409 ProSitePatterns PS00216 Sugar transport proteins signature 1. 279 296 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS08785 a5855087977544961aa8664a94a6ae85 409 Gene3D G3DSA:1.20.1250.20 4 203 2.5E-34 T 29-03-2018 CVS48_RS08785 a5855087977544961aa8664a94a6ae85 409 Gene3D G3DSA:1.20.1250.20 204 409 4.9E-31 T 29-03-2018 CVS48_RS08785 a5855087977544961aa8664a94a6ae85 409 ProSitePatterns PS00217 Sugar transport proteins signature 2. 110 135 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS10255 eec096f8017c264d3ed36874e7f526cf 210 Pfam PF13759 Putative 2OG-Fe(II) oxygenase 105 201 1.1E-14 T 29-03-2018 IPR012668 Conserved hypothetical protein CHP02466 CVS48_RS10255 eec096f8017c264d3ed36874e7f526cf 210 Gene3D G3DSA:2.60.120.620 21 210 2.4E-23 T 29-03-2018 CVS48_RS13640 e851d563119e437a9d7856b256b345ab 192 Pfam PF01965 DJ-1/PfpI family 3 184 3.5E-50 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS13640 e851d563119e437a9d7856b256b345ab 192 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 5 186 8.4E-55 T 29-03-2018 IPR006286 Peptidase C56, PfpI CVS48_RS13640 e851d563119e437a9d7856b256b345ab 192 SUPERFAMILY SSF52317 3 187 2.58E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS13640 e851d563119e437a9d7856b256b345ab 192 Gene3D G3DSA:3.40.50.880 1 190 7.9E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 Gene3D G3DSA:1.10.275.10 1 112 1.2E-14 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 SUPERFAMILY SSF48557 10 457 5.81E-110 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 Pfam PF10397 Adenylosuccinate lyase C-terminus 374 455 7.3E-15 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 ProSitePatterns PS00163 Fumarate lyases signature. 285 294 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 9 358 6.2E-122 T 29-03-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 Pfam PF00206 Lyase 21 308 1.1E-50 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 3.2E-24 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 PRINTS PR00149 Fumarate lyase superfamily signature 285 301 3.2E-24 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 3.2E-24 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 3.2E-24 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 SMART SM00998 373 456 3.7E-16 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 2.3E-8 T 29-03-2018 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 2.3E-8 T 29-03-2018 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 PRINTS PR00145 Argininosuccinate lyase family signature 285 301 2.3E-8 T 29-03-2018 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 2.3E-8 T 29-03-2018 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 Gene3D G3DSA:1.10.40.30 381 456 1.1E-16 T 29-03-2018 CVS48_RS25180 76a7162953a94ebeb3415c083436cdb9 470 Gene3D G3DSA:1.20.200.10 113 380 7.8E-82 T 29-03-2018 CVS48_RS07800 078e769fda42f06902747080707cad43 41 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 30 1.4E-20 T 29-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 CVS48_RS07800 078e769fda42f06902747080707cad43 41 Pfam PF08173 Membrane bound YbgT-like protein 1 27 1.6E-16 T 29-03-2018 IPR012994 Membrane bound YbgT-like CVS48_RS16615 199df2a5fc8935e264b7ac295791cd3c 499 Pfam PF07364 Metallopeptidase family M81 2 285 1.5E-90 T 29-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CVS48_RS16615 199df2a5fc8935e264b7ac295791cd3c 499 Gene3D G3DSA:3.40.50.2300 191 405 0.023 T 29-03-2018 CVS48_RS16615 199df2a5fc8935e264b7ac295791cd3c 499 Pfam PF07171 MlrC C-terminus 298 479 1.7E-50 T 29-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CVS48_RS16615 199df2a5fc8935e264b7ac295791cd3c 499 Gene3D G3DSA:3.40.50.2300 37 186 0.45 T 29-03-2018 CVS48_RS16615 199df2a5fc8935e264b7ac295791cd3c 499 PIRSF PIRSF012702 1 498 1.1E-158 T 29-03-2018 IPR009197 Microcystin LR degradation protein MlrC CVS48_RS09975 ca0817018d1395d85ab03095a64cd8da 304 Pfam PF05853 beta-keto acid cleavage enzyme 5 292 1.5E-88 T 29-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CVS48_RS09975 ca0817018d1395d85ab03095a64cd8da 304 Gene3D G3DSA:3.20.20.70 1 299 2.8E-90 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS00565 125a42b4a04b156ebdbe7cfa910c5c13 140 Pfam PF03960 ArsC family 7 115 1.5E-18 T 29-03-2018 IPR006660 Arsenate reductase-like CVS48_RS00565 125a42b4a04b156ebdbe7cfa910c5c13 140 Gene3D G3DSA:3.40.30.10 1 140 1.4E-45 T 29-03-2018 CVS48_RS00565 125a42b4a04b156ebdbe7cfa910c5c13 140 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 9.8E-41 T 29-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 CVS48_RS00565 125a42b4a04b156ebdbe7cfa910c5c13 140 SUPERFAMILY SSF52833 3 138 8.81E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS17885 d17a84e948aba5b56eeb3896133c9136 280 SUPERFAMILY SSF53850 20 249 1.16E-39 T 29-03-2018 CVS48_RS17885 d17a84e948aba5b56eeb3896133c9136 280 Gene3D G3DSA:3.40.190.10 133 207 1.2E-11 T 29-03-2018 CVS48_RS17885 d17a84e948aba5b56eeb3896133c9136 280 Gene3D G3DSA:3.40.190.10 19 132 1.7E-23 T 29-03-2018 CVS48_RS17885 d17a84e948aba5b56eeb3896133c9136 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 30 241 4.2E-33 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS17885 d17a84e948aba5b56eeb3896133c9136 280 SMART SM00062 29 254 3.1E-33 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS03250 3b117cecfcb37fde3853ddaeebff8d0a 241 SUPERFAMILY SSF53955 64 237 2.02E-59 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS03250 3b117cecfcb37fde3853ddaeebff8d0a 241 Gene3D G3DSA:1.10.3810.10 46 240 1.2E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CVS48_RS03250 3b117cecfcb37fde3853ddaeebff8d0a 241 Pfam PF00912 Transglycosylase 67 235 2.7E-55 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CVS48_RS03250 3b117cecfcb37fde3853ddaeebff8d0a 241 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 13 241 41.622 T 29-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 CVS48_RS03250 3b117cecfcb37fde3853ddaeebff8d0a 241 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 18 240 2.2E-88 T 29-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 CVS48_RS16250 f184ac7b261fd8e206a34f5a04550484 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 1.2E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS16250 f184ac7b261fd8e206a34f5a04550484 314 SUPERFAMILY SSF161098 91 297 1.96E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS16250 f184ac7b261fd8e206a34f5a04550484 314 Gene3D G3DSA:1.10.3720.10 2 301 1.7E-42 T 29-03-2018 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 395 412 1.2E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 412 432 1.2E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 Gene3D G3DSA:3.40.50.2300 1 143 4.6E-24 T 29-03-2018 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 Pfam PF02954 Bacterial regulatory protein, Fis family 391 427 2.4E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 Gene3D G3DSA:3.40.50.300 144 308 2.0E-19 T 29-03-2018 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 SMART SM00448 4 117 2.6E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 Pfam PF00158 Sigma-54 interaction domain 142 302 2.1E-55 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 Pfam PF00072 Response regulator receiver domain 6 118 1.7E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 SUPERFAMILY SSF52540 139 374 3.07E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 Gene3D G3DSA:1.10.10.60 389 428 5.3E-11 T 29-03-2018 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 SUPERFAMILY SSF52172 2 180 8.11E-30 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 Gene3D G3DSA:1.10.8.60 309 388 1.1E-11 T 29-03-2018 CVS48_RS05565 634110892ecdd0ce244c3bc0fcb852bd 439 SUPERFAMILY SSF46689 382 427 1.76E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS14425 434d03b4b4526f1e664f77e1af806343 212 SUPERFAMILY SSF52833 46 169 2.7E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS14425 434d03b4b4526f1e664f77e1af806343 212 Gene3D G3DSA:3.40.30.10 35 207 2.9E-17 T 29-03-2018 CVS48_RS14425 434d03b4b4526f1e664f77e1af806343 212 TIGRFAM TIGR02661 MauD: methylamine dehydrogenase accessory protein MauD 4 191 1.3E-63 T 29-03-2018 IPR013478 Methylamine dehydrogenase accessory protein MauD GO:0030416 CVS48_RS14425 434d03b4b4526f1e664f77e1af806343 212 Pfam PF13098 Thioredoxin-like domain 76 175 2.2E-7 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS04990 a2c45bc6a0b551afddaa1fb01f63dd82 278 SUPERFAMILY SSF56300 17 266 1.04E-48 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS04990 a2c45bc6a0b551afddaa1fb01f63dd82 278 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 206 261 1.0E-21 T 29-03-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 CVS48_RS04990 a2c45bc6a0b551afddaa1fb01f63dd82 278 Gene3D G3DSA:3.60.21.10 6 272 3.9E-41 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS04990 a2c45bc6a0b551afddaa1fb01f63dd82 278 Pfam PF00149 Calcineurin-like phosphoesterase 18 206 2.5E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS04990 a2c45bc6a0b551afddaa1fb01f63dd82 278 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 15 261 36.282 T 29-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CVS48_RS06575 ba39f5ae2407dc2a479e543bf5fec41e 130 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06575 ba39f5ae2407dc2a479e543bf5fec41e 130 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.876 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06575 ba39f5ae2407dc2a479e543bf5fec41e 130 Pfam PF01196 Ribosomal protein L17 20 116 5.6E-35 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06575 ba39f5ae2407dc2a479e543bf5fec41e 130 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 1.7E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06575 ba39f5ae2407dc2a479e543bf5fec41e 130 SUPERFAMILY SSF64263 1 119 3.92E-50 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06575 ba39f5ae2407dc2a479e543bf5fec41e 130 Gene3D G3DSA:3.90.1030.10 1 117 1.0E-49 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS05475 bff8cdace97bad841e0fac2e5da6d505 397 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 8 391 3.7E-113 T 29-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CVS48_RS05475 bff8cdace97bad841e0fac2e5da6d505 397 SUPERFAMILY SSF53383 43 391 7.32E-91 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS05475 bff8cdace97bad841e0fac2e5da6d505 397 Gene3D G3DSA:3.90.1150.10 263 397 2.8E-34 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS05475 bff8cdace97bad841e0fac2e5da6d505 397 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 390 3.2E-95 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS05475 bff8cdace97bad841e0fac2e5da6d505 397 PIRSF PIRSF001434 1 393 6.9E-119 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS05475 bff8cdace97bad841e0fac2e5da6d505 397 Gene3D G3DSA:3.40.640.10 4 261 1.7E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS05475 bff8cdace97bad841e0fac2e5da6d505 397 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 203 217 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 Gene3D G3DSA:3.40.190.10 176 262 2.8E-15 T 29-03-2018 CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.4E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 Pfam PF03466 LysR substrate binding domain 88 294 7.7E-24 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 Gene3D G3DSA:3.40.190.10 91 175 5.5E-15 T 29-03-2018 CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 Gene3D G3DSA:1.10.10.10 1 90 4.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 SUPERFAMILY SSF53850 91 298 4.75E-23 T 29-03-2018 CVS48_RS21005 414898eea6d5e1de2d6ad2b968cfa0df 329 SUPERFAMILY SSF46785 1 85 9.26E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16845 b8f5e7d643fe5ec9e269817c6847c315 158 SUPERFAMILY SSF140566 4 128 2.22E-20 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CVS48_RS16845 b8f5e7d643fe5ec9e269817c6847c315 158 Pfam PF05130 FlgN protein 4 144 6.4E-24 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CVS48_RS16845 b8f5e7d643fe5ec9e269817c6847c315 158 Gene3D G3DSA:1.20.58.300 2 128 2.5E-24 T 29-03-2018 CVS48_RS24415 b4f32159b95bfc47d46def843c1ad19b 392 Gene3D G3DSA:3.90.226.10 23 196 2.1E-25 T 29-03-2018 CVS48_RS24415 b4f32159b95bfc47d46def843c1ad19b 392 Pfam PF00574 Clp protease 42 185 7.9E-23 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CVS48_RS24415 b4f32159b95bfc47d46def843c1ad19b 392 PRINTS PR00127 Clp protease catalytic subunit P signature 107 126 2.5E-5 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS24415 b4f32159b95bfc47d46def843c1ad19b 392 PRINTS PR00127 Clp protease catalytic subunit P signature 57 77 2.5E-5 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS24415 b4f32159b95bfc47d46def843c1ad19b 392 PRINTS PR00127 Clp protease catalytic subunit P signature 164 183 2.5E-5 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CVS48_RS24415 b4f32159b95bfc47d46def843c1ad19b 392 SUPERFAMILY SSF52096 25 188 4.98E-36 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS03465 964e885672ffdd7554d16c61884b09a6 262 Gene3D G3DSA:3.40.50.300 2 262 9.3E-53 T 29-03-2018 CVS48_RS03465 964e885672ffdd7554d16c61884b09a6 262 SMART SM00382 40 260 5.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03465 964e885672ffdd7554d16c61884b09a6 262 SUPERFAMILY SSF52540 14 258 2.0E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03465 964e885672ffdd7554d16c61884b09a6 262 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 235 257 1.5E-12 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS03465 964e885672ffdd7554d16c61884b09a6 262 Pfam PF00005 ABC transporter 32 188 2.1E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS01905 cf914cf484ab92b1d93f7ee484ea3be5 318 SUPERFAMILY SSF51412 10 294 4.94E-54 T 29-03-2018 CVS48_RS01905 cf914cf484ab92b1d93f7ee484ea3be5 318 Gene3D G3DSA:3.20.20.70 7 317 1.3E-34 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS01905 cf914cf484ab92b1d93f7ee484ea3be5 318 Pfam PF03060 Nitronate monooxygenase 81 307 7.6E-23 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CVS48_RS08095 a9e32bf5c755cd7b7caa6696cd44dee2 386 SUPERFAMILY SSF56529 157 360 7.06E-25 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS08095 a9e32bf5c755cd7b7caa6696cd44dee2 386 Gene3D G3DSA:3.90.850.10 78 363 2.7E-25 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS08095 a9e32bf5c755cd7b7caa6696cd44dee2 386 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 214 360 2.7E-6 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS18990 48f16a119c3458580881657f611720e2 301 SUPERFAMILY SSF141868 25 262 5.62E-65 T 29-03-2018 IPR001633 EAL domain CVS48_RS18990 48f16a119c3458580881657f611720e2 301 Pfam PF00563 EAL domain 25 251 5.7E-58 T 29-03-2018 IPR001633 EAL domain CVS48_RS18990 48f16a119c3458580881657f611720e2 301 SMART SM00052 10 256 1.3E-52 T 29-03-2018 IPR001633 EAL domain CVS48_RS18990 48f16a119c3458580881657f611720e2 301 Gene3D G3DSA:3.20.20.450 3 260 2.7E-67 T 29-03-2018 IPR001633 EAL domain CVS48_RS02420 22127f910b66cf4e499759880d3f2fb9 242 Pfam PF13468 Glyoxalase-like domain 10 184 1.2E-31 T 29-03-2018 IPR025870 Glyoxalase-like domain CVS48_RS02420 22127f910b66cf4e499759880d3f2fb9 242 SUPERFAMILY SSF54593 5 123 1.14E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS02420 22127f910b66cf4e499759880d3f2fb9 242 Gene3D G3DSA:3.10.180.10 3 168 7.0E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS15870 41f28bf2ef78bbee522a15bf0d177ac0 331 SUPERFAMILY SSF53850 116 280 2.39E-10 T 29-03-2018 CVS48_RS15870 41f28bf2ef78bbee522a15bf0d177ac0 331 Gene3D G3DSA:3.40.190.10 129 259 2.2E-12 T 29-03-2018 CVS48_RS15870 41f28bf2ef78bbee522a15bf0d177ac0 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 327 1.7E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS15870 41f28bf2ef78bbee522a15bf0d177ac0 331 PIRSF PIRSF017082 3 331 1.4E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS19575 38ad57acca6f0a4427aaed441adec93e 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 15.649 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS19575 38ad57acca6f0a4427aaed441adec93e 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 56 8.5E-16 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CVS48_RS19575 38ad57acca6f0a4427aaed441adec93e 67 SMART SM01409 8 59 5.5E-12 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CVS48_RS19575 38ad57acca6f0a4427aaed441adec93e 67 SUPERFAMILY SSF63562 1 63 1.4E-18 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CVS48_RS19575 38ad57acca6f0a4427aaed441adec93e 67 Pfam PF01192 RNA polymerase Rpb6 8 56 7.4E-13 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CVS48_RS19575 38ad57acca6f0a4427aaed441adec93e 67 Gene3D G3DSA:3.90.940.10 1 66 2.5E-17 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CVS48_RS18205 2846d82bb465de757a1c78cbe40f2784 318 Gene3D G3DSA:3.90.260.10 168 272 1.5E-8 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS18205 2846d82bb465de757a1c78cbe40f2784 318 SUPERFAMILY SSF54001 122 310 1.67E-44 T 29-03-2018 CVS48_RS18205 2846d82bb465de757a1c78cbe40f2784 318 Pfam PF01841 Transglutaminase-like superfamily 162 264 2.7E-19 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS18205 2846d82bb465de757a1c78cbe40f2784 318 SMART SM00460 192 266 1.3E-17 T 29-03-2018 IPR002931 Transglutaminase-like CVS48_RS18205 2846d82bb465de757a1c78cbe40f2784 318 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 20 96 6.9E-21 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CVS48_RS17800 f1da004e62eb6ecbd7473e6b4951dcb9 396 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 98 292 1.0E-4 T 29-03-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 CVS48_RS09990 9b00652584cf64119c640f242a136b27 372 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 44 329 1.7E-109 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CVS48_RS09990 9b00652584cf64119c640f242a136b27 372 SMART SM00382 38 221 4.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS09990 9b00652584cf64119c640f242a136b27 372 SUPERFAMILY SSF52540 14 253 2.46E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09990 9b00652584cf64119c640f242a136b27 372 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS09990 9b00652584cf64119c640f242a136b27 372 SUPERFAMILY SSF50331 246 334 1.53E-9 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS09990 9b00652584cf64119c640f242a136b27 372 Pfam PF00005 ABC transporter 29 171 9.1E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS09990 9b00652584cf64119c640f242a136b27 372 Gene3D G3DSA:3.40.50.300 2 250 3.6E-73 T 29-03-2018 CVS48_RS09990 9b00652584cf64119c640f242a136b27 372 Pfam PF08402 TOBE domain 292 369 5.5E-7 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 10 148 8.6E-37 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 Gene3D G3DSA:3.30.360.10 166 322 3.2E-54 T 29-03-2018 CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 9 348 40.988 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 SUPERFAMILY SSF51735 8 173 4.16E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 SMART SM00859 10 148 3.5E-57 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 151 167 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 Gene3D G3DSA:3.40.50.720 2 165 5.9E-46 T 29-03-2018 CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 9 354 1.2E-124 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 175 325 1.2E-16 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS03005 c118f1ae249714065a7edcc67cfe5cd8 354 SUPERFAMILY SSF55347 156 322 1.83E-47 T 29-03-2018 CVS48_RS13620 b794699cd267d778811d64a278c20425 314 Pfam PF03466 LysR substrate binding domain 95 305 5.3E-21 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS13620 b794699cd267d778811d64a278c20425 314 Gene3D G3DSA:3.40.190.10 99 187 1.2E-4 T 29-03-2018 CVS48_RS13620 b794699cd267d778811d64a278c20425 314 Gene3D G3DSA:1.10.10.10 4 91 3.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13620 b794699cd267d778811d64a278c20425 314 Gene3D G3DSA:3.40.190.10 188 277 7.2E-13 T 29-03-2018 CVS48_RS13620 b794699cd267d778811d64a278c20425 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13620 b794699cd267d778811d64a278c20425 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13620 b794699cd267d778811d64a278c20425 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13620 b794699cd267d778811d64a278c20425 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 9.2E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS13620 b794699cd267d778811d64a278c20425 314 SUPERFAMILY SSF46785 4 118 1.24E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS13620 b794699cd267d778811d64a278c20425 314 SUPERFAMILY SSF53850 96 292 1.81E-17 T 29-03-2018 CVS48_RS03060 49816ac94909c9d2b167a52a981cb874 225 Pfam PF02230 Phospholipase/Carboxylesterase 13 222 1.2E-48 T 29-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CVS48_RS03060 49816ac94909c9d2b167a52a981cb874 225 Gene3D G3DSA:3.40.50.1820 6 225 1.4E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03060 49816ac94909c9d2b167a52a981cb874 225 SUPERFAMILY SSF53474 15 224 1.59E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS27635 7cf18afc8892806be0c937a6e1901da5 54 Pfam PF07043 Protein of unknown function (DUF1328) 6 43 3.2E-15 T 29-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 CVS48_RS27635 7cf18afc8892806be0c937a6e1901da5 54 PIRSF PIRSF036466 1 54 3.7E-22 T 29-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 CVS48_RS27635 7cf18afc8892806be0c937a6e1901da5 54 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 51 20.36 T 29-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 CVS48_RS20485 2132d0bc1842cb06a8a94648e06b2937 305 Pfam PF03466 LysR substrate binding domain 89 290 1.1E-24 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS20485 2132d0bc1842cb06a8a94648e06b2937 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.8E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS20485 2132d0bc1842cb06a8a94648e06b2937 305 SUPERFAMILY SSF53850 89 291 5.43E-28 T 29-03-2018 CVS48_RS20485 2132d0bc1842cb06a8a94648e06b2937 305 Gene3D G3DSA:3.40.190.10 181 262 3.2E-10 T 29-03-2018 CVS48_RS20485 2132d0bc1842cb06a8a94648e06b2937 305 SUPERFAMILY SSF46785 2 111 1.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20485 2132d0bc1842cb06a8a94648e06b2937 305 Gene3D G3DSA:1.10.10.10 1 89 1.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20485 2132d0bc1842cb06a8a94648e06b2937 305 Gene3D G3DSA:3.40.190.10 90 180 8.5E-14 T 29-03-2018 CVS48_RS09690 0ab27ad8922cb0fa17a85801bca109e0 119 SUPERFAMILY SSF56784 35 103 1.39E-15 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS09690 0ab27ad8922cb0fa17a85801bca109e0 119 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 33 90 1.2E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS09690 0ab27ad8922cb0fa17a85801bca109e0 119 Gene3D G3DSA:3.40.50.1000 11 117 1.8E-12 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS09690 0ab27ad8922cb0fa17a85801bca109e0 119 Pfam PF13242 HAD-hyrolase-like 52 93 7.1E-9 T 29-03-2018 CVS48_RS13630 d558f8bbe5eb38f31b6e9d8aedd31622 322 Gene3D G3DSA:3.40.190.10 124 285 1.0E-10 T 29-03-2018 CVS48_RS13630 d558f8bbe5eb38f31b6e9d8aedd31622 322 PIRSF PIRSF017082 1 321 1.9E-72 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13630 d558f8bbe5eb38f31b6e9d8aedd31622 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 318 3.3E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13630 d558f8bbe5eb38f31b6e9d8aedd31622 322 SUPERFAMILY SSF53850 110 283 8.42E-15 T 29-03-2018 CVS48_RS09885 45eacc0072c20ac2afb96b64bed89a10 340 Pfam PF05544 Proline racemase 11 330 4.6E-116 T 29-03-2018 IPR008794 Proline racemase family CVS48_RS09885 45eacc0072c20ac2afb96b64bed89a10 340 SUPERFAMILY SSF54506 1 330 2.35E-101 T 29-03-2018 CVS48_RS09885 45eacc0072c20ac2afb96b64bed89a10 340 Gene3D G3DSA:3.10.310.10 153 308 7.9E-47 T 29-03-2018 CVS48_RS09885 45eacc0072c20ac2afb96b64bed89a10 340 Gene3D G3DSA:3.10.310.10 1 152 3.6E-28 T 29-03-2018 CVS48_RS09885 45eacc0072c20ac2afb96b64bed89a10 340 PIRSF PIRSF029792 1 333 3.0E-115 T 29-03-2018 IPR008794 Proline racemase family CVS48_RS19905 952e9f7622313b1882009fb209ddc941 113 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 16 105 5.5E-23 T 29-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CVS48_RS19905 952e9f7622313b1882009fb209ddc941 113 Pfam PF03334 Na+/H+ antiporter subunit 17 97 1.0E-21 T 29-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CVS48_RS24090 3cef15953ead816d2ba463323a0042b3 262 Gene3D G3DSA:3.40.1280.10 1 174 1.7E-38 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CVS48_RS24090 3cef15953ead816d2ba463323a0042b3 262 PIRSF PIRSF004808 3 259 3.0E-60 T 29-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CVS48_RS24090 3cef15953ead816d2ba463323a0042b3 262 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 7 249 5.5E-52 T 29-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CVS48_RS24090 3cef15953ead816d2ba463323a0042b3 262 Pfam PF00588 SpoU rRNA Methylase family 8 162 3.6E-35 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CVS48_RS24090 3cef15953ead816d2ba463323a0042b3 262 SUPERFAMILY SSF75217 7 173 5.82E-30 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 SMART SM00344 8 117 6.4E-39 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 Pfam PF01037 Lrp/AsnC ligand binding domain 74 134 1.0E-16 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 7.1E-18 T 29-03-2018 CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 Gene3D G3DSA:3.30.70.920 61 149 5.3E-22 T 29-03-2018 CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 1.9E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 1.9E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 1.9E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 SUPERFAMILY SSF54909 68 155 9.52E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 ProSitePatterns PS00519 AsnC-type HTH domain signature. 26 52 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 SUPERFAMILY SSF46785 8 98 4.36E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22810 8bed430b9bb31f4fa2fa1e529bfb3c6f 161 Gene3D G3DSA:1.10.10.10 2 59 9.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24170 5bf70c4efa8d8c180745d1d7323bbd24 462 SUPERFAMILY SSF75304 4 456 9.81E-124 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS24170 5bf70c4efa8d8c180745d1d7323bbd24 462 Pfam PF01425 Amidase 22 445 8.1E-94 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS24170 5bf70c4efa8d8c180745d1d7323bbd24 462 TIGRFAM TIGR02715 amido_AtzE: amidohydrolase, AtzE family 6 458 1.8E-199 T 29-03-2018 IPR014087 Amidohydrolase, AtzE type KEGG: 00791+3.5.1.84|MetaCyc: PWY-5169 CVS48_RS24170 5bf70c4efa8d8c180745d1d7323bbd24 462 Gene3D G3DSA:3.90.1300.10 2 462 8.5E-127 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS09240 d2fe27cad35fd0b213ce5369df8e7a67 396 Gene3D G3DSA:1.20.1250.20 3 196 3.8E-18 T 29-03-2018 CVS48_RS09240 d2fe27cad35fd0b213ce5369df8e7a67 396 SUPERFAMILY SSF103473 5 389 6.67E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS09240 d2fe27cad35fd0b213ce5369df8e7a67 396 Gene3D G3DSA:1.20.1250.20 200 392 0.001 T 29-03-2018 CVS48_RS09240 d2fe27cad35fd0b213ce5369df8e7a67 396 Pfam PF07690 Major Facilitator Superfamily 12 336 2.4E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS12640 4136dec98913632f06ca601d035ecab0 279 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 36 279 2.8E-115 T 29-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD CVS48_RS12640 4136dec98913632f06ca601d035ecab0 279 Gene3D G3DSA:3.40.50.300 26 278 3.7E-49 T 29-03-2018 CVS48_RS12640 4136dec98913632f06ca601d035ecab0 279 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 257 278 3.8E-8 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS12640 4136dec98913632f06ca601d035ecab0 279 SUPERFAMILY SSF52540 36 277 7.55E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS12640 4136dec98913632f06ca601d035ecab0 279 Pfam PF00005 ABC transporter 52 207 2.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS13240 a9619525cd0d3d15db4088531ebcadb0 143 SUPERFAMILY SSF51316 1 132 3.24E-48 T 29-03-2018 IPR011057 Mss4-like CVS48_RS13240 a9619525cd0d3d15db4088531ebcadb0 143 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 24 111 1.5E-19 T 29-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CVS48_RS13240 a9619525cd0d3d15db4088531ebcadb0 143 Gene3D G3DSA:3.90.1590.10 1 143 1.5E-39 T 29-03-2018 CVS48_RS27355 24b0a24222470ee0df6e104301b003f8 290 SUPERFAMILY SSF103481 206 287 1.44E-11 T 29-03-2018 CVS48_RS27355 24b0a24222470ee0df6e104301b003f8 290 SUPERFAMILY SSF103481 39 141 1.83E-13 T 29-03-2018 CVS48_RS27355 24b0a24222470ee0df6e104301b003f8 290 Pfam PF00892 EamA-like transporter family 153 287 4.2E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS07105 7b7993812e21592c920882bbdb516ed7 233 Pfam PF10997 Alternate to MurJ 133 226 1.6E-13 T 29-03-2018 IPR021260 Lipid II flippase Amj CVS48_RS00580 6d711afe8b5da0ae8c0156908a7cc85b 176 Gene3D G3DSA:3.40.630.30 3 141 8.9E-23 T 29-03-2018 CVS48_RS00580 6d711afe8b5da0ae8c0156908a7cc85b 176 Pfam PF13527 Acetyltransferase (GNAT) domain 9 137 1.1E-13 T 29-03-2018 CVS48_RS00580 6d711afe8b5da0ae8c0156908a7cc85b 176 SUPERFAMILY SSF55729 7 155 8.23E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS00420 9d7224c492c693526441bb4589ded88e 134 Gene3D G3DSA:3.40.30.10 10 124 1.4E-10 T 29-03-2018 CVS48_RS00420 9d7224c492c693526441bb4589ded88e 134 SUPERFAMILY SSF52833 8 124 3.35E-19 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 SUPERFAMILY SSF54106 422 466 2.75E-10 T 29-03-2018 IPR018392 LysM domain CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 SUPERFAMILY SSF54106 325 370 4.71E-6 T 29-03-2018 IPR018392 LysM domain CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 SUPERFAMILY SSF53955 96 243 4.41E-40 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 SMART SM00257 326 370 0.043 T 29-03-2018 IPR018392 LysM domain CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 SMART SM00257 423 466 7.2E-15 T 29-03-2018 IPR018392 LysM domain CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 Pfam PF01464 Transglycosylase SLT domain 107 209 7.6E-24 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 Gene3D G3DSA:3.10.350.10 418 471 5.1E-13 T 29-03-2018 CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 Gene3D G3DSA:1.10.530.10 79 246 2.4E-32 T 29-03-2018 CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 117 145 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 Pfam PF01476 LysM domain 424 466 5.3E-13 T 29-03-2018 IPR018392 LysM domain CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 Pfam PF01476 LysM domain 330 370 4.0E-6 T 29-03-2018 IPR018392 LysM domain CVS48_RS02855 6af4dc2506e402af4ef2f2085a44d760 472 Gene3D G3DSA:3.10.350.10 318 414 8.3E-7 T 29-03-2018 CVS48_RS10375 1d1cc27eff364464c7412f969473e7de 308 SUPERFAMILY SSF46785 1 108 3.27E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10375 1d1cc27eff364464c7412f969473e7de 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.1E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10375 1d1cc27eff364464c7412f969473e7de 308 Gene3D G3DSA:3.40.190.10 85 175 3.6E-17 T 29-03-2018 CVS48_RS10375 1d1cc27eff364464c7412f969473e7de 308 Gene3D G3DSA:3.40.190.10 176 265 1.7E-15 T 29-03-2018 CVS48_RS10375 1d1cc27eff364464c7412f969473e7de 308 Gene3D G3DSA:1.10.10.10 1 83 2.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10375 1d1cc27eff364464c7412f969473e7de 308 Pfam PF03466 LysR substrate binding domain 85 284 1.2E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS10375 1d1cc27eff364464c7412f969473e7de 308 SUPERFAMILY SSF53850 87 296 4.81E-33 T 29-03-2018 CVS48_RS18945 fa7fbe52f54fae0463be079226b846d8 334 Gene3D G3DSA:3.40.50.1000 62 329 3.9E-14 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS18945 fa7fbe52f54fae0463be079226b846d8 334 Pfam PF12710 haloacid dehalogenase-like hydrolase 65 269 2.7E-24 T 29-03-2018 CVS48_RS18945 fa7fbe52f54fae0463be079226b846d8 334 SUPERFAMILY SSF56784 63 315 3.14E-21 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS19490 0ca3da94115428d6196bafde6f41f968 207 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 13 204 1.5E-49 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CVS48_RS19490 0ca3da94115428d6196bafde6f41f968 207 Pfam PF01725 Ham1 family 13 201 6.7E-51 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CVS48_RS19490 0ca3da94115428d6196bafde6f41f968 207 SUPERFAMILY SSF52972 10 204 1.81E-66 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CVS48_RS19490 0ca3da94115428d6196bafde6f41f968 207 Gene3D G3DSA:3.90.950.10 2 207 1.2E-71 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CVS48_RS19490 0ca3da94115428d6196bafde6f41f968 207 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 11 206 44.627 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CVS48_RS03205 5a748670c276782942a761d9079abd9f 200 SUPERFAMILY SSF53474 2 190 4.72E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03205 5a748670c276782942a761d9079abd9f 200 Gene3D G3DSA:3.40.50.1820 1 195 5.1E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03205 5a748670c276782942a761d9079abd9f 200 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 191 9.6E-51 T 29-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA CVS48_RS01260 ea25ab825111aad8c5692aa628fce4a5 196 Pfam PF11161 Protein of unknown function (DUF2946) 1 195 3.4E-62 T 29-03-2018 IPR021332 Protein of unknown function DUF2944 CVS48_RS27545 3f5ec0d8b9471ef47d657ac711c65c24 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 71 183 9.0E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS27545 3f5ec0d8b9471ef47d657ac711c65c24 224 SUPERFAMILY SSF56784 4 215 3.66E-51 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS27545 3f5ec0d8b9471ef47d657ac711c65c24 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 87 179 9.7E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CVS48_RS27545 3f5ec0d8b9471ef47d657ac711c65c24 224 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 5 203 2.4E-53 T 29-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 CVS48_RS27545 3f5ec0d8b9471ef47d657ac711c65c24 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 1.8E-31 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS27545 3f5ec0d8b9471ef47d657ac711c65c24 224 Gene3D G3DSA:3.40.50.1000 76 221 4.1E-28 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS27545 3f5ec0d8b9471ef47d657ac711c65c24 224 Gene3D G3DSA:1.10.150.240 17 75 8.9E-12 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CVS48_RS28630 4c49449bacd2725e2511602ff51112ae 759 Pfam PF07715 TonB-dependent Receptor Plug Domain 70 167 1.2E-16 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS28630 4c49449bacd2725e2511602ff51112ae 759 Gene3D G3DSA:2.40.170.20 181 759 2.5E-86 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS28630 4c49449bacd2725e2511602ff51112ae 759 Gene3D G3DSA:2.170.130.10 35 175 4.8E-23 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS28630 4c49449bacd2725e2511602ff51112ae 759 SUPERFAMILY SSF56935 40 759 2.24E-128 T 29-03-2018 CVS48_RS28630 4c49449bacd2725e2511602ff51112ae 759 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 71 757 2.0E-83 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS28630 4c49449bacd2725e2511602ff51112ae 759 Pfam PF00593 TonB dependent receptor 240 758 1.3E-55 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS14540 45afbf6b16bbc6fd6494726d9f95e859 105 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.7E-32 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CVS48_RS14540 45afbf6b16bbc6fd6494726d9f95e859 105 SUPERFAMILY SSF103481 5 104 3.14E-20 T 29-03-2018 CVS48_RS19265 5237dda1511e14c9eda32ff661b9d545 247 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 85 93 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS19265 5237dda1511e14c9eda32ff661b9d545 247 Gene3D G3DSA:3.40.50.1860 8 130 2.8E-32 T 29-03-2018 CVS48_RS19265 5237dda1511e14c9eda32ff661b9d545 247 SUPERFAMILY SSF53681 10 121 5.23E-31 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS19265 5237dda1511e14c9eda32ff661b9d545 247 Pfam PF01177 Asp/Glu/Hydantoin racemase 13 232 1.1E-59 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS19265 5237dda1511e14c9eda32ff661b9d545 247 Gene3D G3DSA:3.40.50.1860 131 237 6.1E-21 T 29-03-2018 CVS48_RS19265 5237dda1511e14c9eda32ff661b9d545 247 SUPERFAMILY SSF53681 126 235 4.58E-24 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CVS48_RS19265 5237dda1511e14c9eda32ff661b9d545 247 TIGRFAM TIGR00035 asp_race: aspartate racemase 10 234 1.0E-44 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CVS48_RS18260 17a632c6bb9b669f8f377d6c03e37f6f 376 Gene3D G3DSA:2.130.10.10 224 375 1.0E-19 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS18260 17a632c6bb9b669f8f377d6c03e37f6f 376 SUPERFAMILY SSF50974 95 370 3.66E-35 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CVS48_RS18260 17a632c6bb9b669f8f377d6c03e37f6f 376 Gene3D G3DSA:2.130.10.10 154 223 4.2E-7 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS18260 17a632c6bb9b669f8f377d6c03e37f6f 376 Gene3D G3DSA:2.130.10.10 11 153 3.2E-10 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS10300 62ec285ef2895f3f9cc509ed948396cf 345 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 3 256 2.8E-70 T 29-03-2018 IPR018712 Domain of unknown function DUF2235 CVS48_RS10300 62ec285ef2895f3f9cc509ed948396cf 345 SUPERFAMILY SSF53474 6 201 1.88E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS10300 62ec285ef2895f3f9cc509ed948396cf 345 Gene3D G3DSA:3.40.50.1820 14 306 6.5E-4 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS15960 a3188cd02a9fecc2fe1e6d73213f9c2b 267 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 4 260 4.2E-102 T 29-03-2018 IPR010247 N-formylglutamate deformylase CVS48_RS15960 a3188cd02a9fecc2fe1e6d73213f9c2b 267 SUPERFAMILY SSF53187 4 260 3.01E-80 T 29-03-2018 CVS48_RS15960 a3188cd02a9fecc2fe1e6d73213f9c2b 267 Pfam PF05013 N-formylglutamate amidohydrolase 12 231 2.2E-69 T 29-03-2018 IPR007709 N-formylglutamate amidohydrolase CVS48_RS15960 a3188cd02a9fecc2fe1e6d73213f9c2b 267 Gene3D G3DSA:3.40.630.40 1 266 8.3E-81 T 29-03-2018 CVS48_RS25525 f77d3801bfe91a0a0a3ac74a679650ab 481 Gene3D G3DSA:3.90.350.10 127 443 2.3E-6 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CVS48_RS25525 f77d3801bfe91a0a0a3ac74a679650ab 481 Pfam PF13751 Transposase DDE domain 348 463 4.9E-15 T 29-03-2018 IPR025668 Transposase DDE domain CVS48_RS25525 f77d3801bfe91a0a0a3ac74a679650ab 481 Pfam PF05598 Transposase domain (DUF772) 56 121 6.9E-18 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CVS48_RS25795 f77d3801bfe91a0a0a3ac74a679650ab 481 Gene3D G3DSA:3.90.350.10 127 443 2.3E-6 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CVS48_RS25795 f77d3801bfe91a0a0a3ac74a679650ab 481 Pfam PF13751 Transposase DDE domain 348 463 4.9E-15 T 29-03-2018 IPR025668 Transposase DDE domain CVS48_RS25795 f77d3801bfe91a0a0a3ac74a679650ab 481 Pfam PF05598 Transposase domain (DUF772) 56 121 6.9E-18 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CVS48_RS12475 3feaabc7b054e85a0643fda024e17cf0 210 Gene3D G3DSA:3.40.30.10 46 210 2.2E-33 T 29-03-2018 CVS48_RS12475 3feaabc7b054e85a0643fda024e17cf0 210 Pfam PF02630 SCO1/SenC 57 192 3.2E-39 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12475 3feaabc7b054e85a0643fda024e17cf0 210 SUPERFAMILY SSF52833 54 209 7.11E-49 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 PRINTS PR00721 Stomatin signature 75 96 4.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 PRINTS PR00721 Stomatin signature 28 50 4.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 PRINTS PR00721 Stomatin signature 110 127 4.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 PRINTS PR00721 Stomatin signature 198 221 4.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 PRINTS PR00721 Stomatin signature 154 172 4.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 PRINTS PR00721 Stomatin signature 173 194 4.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 PRINTS PR00721 Stomatin signature 130 153 4.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 Pfam PF01145 SPFH domain / Band 7 family 26 195 5.6E-33 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 SMART SM00244 21 178 1.2E-55 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS02220 d37fd214d9df2fca951f3e5171936b7e 261 SUPERFAMILY SSF117892 52 185 7.59E-42 T 29-03-2018 IPR001107 Band 7 domain CVS48_RS16975 2b59586e76e87b569824a41735a8d26d 461 Pfam PF02120 Flagellar hook-length control protein FliK 336 414 2.5E-22 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CVS48_RS16975 2b59586e76e87b569824a41735a8d26d 461 PRINTS PR01007 Flagellar hook-length control protein signature 366 381 6.0E-15 T 29-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 CVS48_RS16975 2b59586e76e87b569824a41735a8d26d 461 PRINTS PR01007 Flagellar hook-length control protein signature 381 404 6.0E-15 T 29-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 CVS48_RS16975 2b59586e76e87b569824a41735a8d26d 461 PRINTS PR01007 Flagellar hook-length control protein signature 348 366 6.0E-15 T 29-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 CVS48_RS16975 2b59586e76e87b569824a41735a8d26d 461 PRINTS PR01007 Flagellar hook-length control protein signature 67 84 6.0E-15 T 29-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 CVS48_RS15930 ab598dbee29438f47c9c00cbb9bab204 325 SUPERFAMILY SSF53850 31 259 6.58E-42 T 29-03-2018 CVS48_RS15930 ab598dbee29438f47c9c00cbb9bab204 325 Gene3D G3DSA:3.40.190.10 23 125 4.0E-12 T 29-03-2018 CVS48_RS15930 ab598dbee29438f47c9c00cbb9bab204 325 Pfam PF09084 NMT1/THI5 like 37 253 8.8E-27 T 29-03-2018 IPR015168 SsuA/THI5-like CVS48_RS15930 ab598dbee29438f47c9c00cbb9bab204 325 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 30 325 1.4E-52 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CVS48_RS15930 ab598dbee29438f47c9c00cbb9bab204 325 Gene3D G3DSA:3.40.190.10 126 325 1.6E-33 T 29-03-2018 CVS48_RS27845 5634b9fba2fb6fe484b94b3b780b2eab 409 SUPERFAMILY SSF53187 319 406 3.01E-51 T 29-03-2018 CVS48_RS27845 5634b9fba2fb6fe484b94b3b780b2eab 409 SUPERFAMILY SSF53187 7 194 3.01E-51 T 29-03-2018 CVS48_RS27845 5634b9fba2fb6fe484b94b3b780b2eab 409 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 88 97 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CVS48_RS27845 5634b9fba2fb6fe484b94b3b780b2eab 409 Pfam PF01546 Peptidase family M20/M25/M40 89 403 5.9E-26 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS27845 5634b9fba2fb6fe484b94b3b780b2eab 409 Gene3D G3DSA:3.40.630.10 2 300 3.6E-58 T 29-03-2018 CVS48_RS27845 5634b9fba2fb6fe484b94b3b780b2eab 409 SUPERFAMILY SSF55031 195 310 4.78E-23 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS27845 5634b9fba2fb6fe484b94b3b780b2eab 409 Pfam PF07687 Peptidase dimerisation domain 191 301 1.3E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS07655 f3f319f22115188e748db68ed5df72b7 349 SUPERFAMILY SSF89733 1 346 1.7E-99 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CVS48_RS07655 f3f319f22115188e748db68ed5df72b7 349 Gene3D G3DSA:3.30.1370.60 80 309 4.3E-78 T 29-03-2018 CVS48_RS07655 f3f319f22115188e748db68ed5df72b7 349 Gene3D G3DSA:1.10.1530.10 2 79 1.2E-22 T 29-03-2018 CVS48_RS07655 f3f319f22115188e748db68ed5df72b7 349 Pfam PF02615 Malate/L-lactate dehydrogenase 4 335 1.8E-100 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CVS48_RS05740 e3218415fa143d7b6e51d2a4a9664614 283 Gene3D G3DSA:1.10.3720.10 77 276 1.2E-23 T 29-03-2018 CVS48_RS05740 e3218415fa143d7b6e51d2a4a9664614 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 273 1.1E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05740 e3218415fa143d7b6e51d2a4a9664614 283 SUPERFAMILY SSF161098 83 262 3.53E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18750 c5fbaf3975288d4616696cea6bf0d932 289 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 13 270 1.5E-71 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CVS48_RS18750 c5fbaf3975288d4616696cea6bf0d932 289 Gene3D G3DSA:3.60.21.10 7 282 2.5E-40 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS18750 c5fbaf3975288d4616696cea6bf0d932 289 PIRSF PIRSF000903 10 280 2.6E-90 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CVS48_RS18750 c5fbaf3975288d4616696cea6bf0d932 289 Pfam PF00149 Calcineurin-like phosphoesterase 11 135 2.3E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS18750 c5fbaf3975288d4616696cea6bf0d932 289 SUPERFAMILY SSF56300 11 264 2.67E-46 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS07205 4ba6f50d669577e6f565cf6e06a5f496 90 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 2 90 20.642 T 29-03-2018 IPR007454 Uncharacterised protein family UPF0250 CVS48_RS07205 4ba6f50d669577e6f565cf6e06a5f496 90 Pfam PF04359 Protein of unknown function (DUF493) 7 90 7.0E-28 T 29-03-2018 IPR007454 Uncharacterised protein family UPF0250 CVS48_RS07205 4ba6f50d669577e6f565cf6e06a5f496 90 Gene3D G3DSA:3.30.70.260 6 90 2.8E-28 T 29-03-2018 CVS48_RS07205 4ba6f50d669577e6f565cf6e06a5f496 90 SUPERFAMILY SSF117991 6 90 1.01E-25 T 29-03-2018 IPR027471 YbeD-like domain CVS48_RS27995 2bc16f3170fccbe838c69974d307ed2b 94 SUPERFAMILY SSF54909 1 94 1.18E-25 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS27995 2bc16f3170fccbe838c69974d307ed2b 94 Gene3D G3DSA:3.30.70.100 1 94 2.4E-26 T 29-03-2018 CVS48_RS27995 2bc16f3170fccbe838c69974d307ed2b 94 Pfam PF07045 Domain of unknown function (DUF1330) 2 94 5.2E-33 T 29-03-2018 IPR010753 Domain of unknown function DUF1330 CVS48_RS00715 6f7827e988e0e55dbee40f614fc98000 304 SMART SM00382 64 212 3.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS00715 6f7827e988e0e55dbee40f614fc98000 304 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 68 86 1.6E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS00715 6f7827e988e0e55dbee40f614fc98000 304 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 140 158 1.6E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CVS48_RS00715 6f7827e988e0e55dbee40f614fc98000 304 SUPERFAMILY SSF52540 29 293 6.49E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00715 6f7827e988e0e55dbee40f614fc98000 304 Gene3D G3DSA:3.40.50.300 15 235 2.0E-28 T 29-03-2018 CVS48_RS00715 6f7827e988e0e55dbee40f614fc98000 304 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 68 212 1.1E-24 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 SUPERFAMILY SSF55831 1 124 2.88E-96 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 SUPERFAMILY SSF55831 151 323 2.88E-96 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 Gene3D G3DSA:3.30.572.10 1 323 1.4E-97 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 ProSitePatterns PS00091 Thymidylate synthase active site. 172 199 - T 29-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 PRINTS PR00108 Thymidylate synthase family signature 187 202 2.5E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 PRINTS PR00108 Thymidylate synthase family signature 42 63 2.5E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 PRINTS PR00108 Thymidylate synthase family signature 245 262 2.5E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 PRINTS PR00108 Thymidylate synthase family signature 207 233 2.5E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 PRINTS PR00108 Thymidylate synthase family signature 161 180 2.5E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 153 323 6.0E-36 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 Hamap MF_00008 Thymidylate synthase [thyA]. 1 323 35.112 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10660 c4e0de18114355b38b49a47edb3ed4ad 323 Pfam PF00303 Thymidylate synthase 2 323 1.7E-87 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CVS48_RS10790 1f7020e7206c26bce162110b8c0bec91 377 Gene3D G3DSA:3.30.420.10 126 329 4.2E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS10790 1f7020e7206c26bce162110b8c0bec91 377 Pfam PF13518 Helix-turn-helix domain 12 62 6.5E-12 T 29-03-2018 CVS48_RS10790 1f7020e7206c26bce162110b8c0bec91 377 SUPERFAMILY SSF46689 11 115 2.15E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS10790 1f7020e7206c26bce162110b8c0bec91 377 Pfam PF00665 Integrase core domain 134 257 2.2E-25 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS10790 1f7020e7206c26bce162110b8c0bec91 377 Gene3D G3DSA:1.10.10.10 10 65 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10790 1f7020e7206c26bce162110b8c0bec91 377 SUPERFAMILY SSF53098 130 302 3.67E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS09485 a7058813c043cbb2ff36c148494ec293 591 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 273 3.0E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09485 a7058813c043cbb2ff36c148494ec293 591 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 409 587 5.1E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09485 a7058813c043cbb2ff36c148494ec293 591 Gene3D G3DSA:1.10.3720.10 338 589 7.0E-38 T 29-03-2018 CVS48_RS09485 a7058813c043cbb2ff36c148494ec293 591 Gene3D G3DSA:1.10.3720.10 16 279 6.1E-42 T 29-03-2018 CVS48_RS09485 a7058813c043cbb2ff36c148494ec293 591 SUPERFAMILY SSF161098 338 589 8.22E-51 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS09485 a7058813c043cbb2ff36c148494ec293 591 SUPERFAMILY SSF161098 14 279 2.9E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19055 91d6175fc89b77597888d774b8d03558 92 Pfam PF04070 Domain of unknown function (DUF378) 30 85 2.3E-8 T 29-03-2018 IPR007211 Protein of unknown function DUF378 CVS48_RS21305 704396db48f140658f1f91d9d532b69b 432 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 422 1.2E-96 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS21305 704396db48f140658f1f91d9d532b69b 432 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 427 4.0E-102 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS21305 704396db48f140658f1f91d9d532b69b 432 PIRSF PIRSF006066 1 432 3.8E-119 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS16660 6ac5dca7d0efb3ff51461a345e7eab39 688 Gene3D G3DSA:1.10.1370.10 452 688 9.8E-59 T 29-03-2018 CVS48_RS16660 6ac5dca7d0efb3ff51461a345e7eab39 688 Gene3D G3DSA:1.10.1370.10 142 431 2.0E-50 T 29-03-2018 CVS48_RS16660 6ac5dca7d0efb3ff51461a345e7eab39 688 Pfam PF01432 Peptidase family M3 224 684 4.2E-124 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CVS48_RS16660 6ac5dca7d0efb3ff51461a345e7eab39 688 SUPERFAMILY SSF55486 4 684 8.55E-177 T 29-03-2018 CVS48_RS16660 6ac5dca7d0efb3ff51461a345e7eab39 688 Gene3D G3DSA:1.20.1050.40 7 140 4.6E-34 T 29-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal CVS48_RS16140 124274f4b74491748cf87486468a7406 793 Pfam PF00263 Bacterial type II and III secretion system protein 515 682 7.8E-51 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CVS48_RS16140 124274f4b74491748cf87486468a7406 793 Pfam PF03958 Bacterial type II/III secretion system short domain 223 290 1.1E-10 T 29-03-2018 IPR005644 NolW-like CVS48_RS16140 124274f4b74491748cf87486468a7406 793 Pfam PF03958 Bacterial type II/III secretion system short domain 296 428 5.8E-12 T 29-03-2018 IPR005644 NolW-like CVS48_RS16140 124274f4b74491748cf87486468a7406 793 Pfam PF03958 Bacterial type II/III secretion system short domain 159 218 5.9E-14 T 29-03-2018 IPR005644 NolW-like CVS48_RS16140 124274f4b74491748cf87486468a7406 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 428 438 2.0E-29 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS16140 124274f4b74491748cf87486468a7406 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 546 556 2.0E-29 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS16140 124274f4b74491748cf87486468a7406 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 646 664 2.0E-29 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS16140 124274f4b74491748cf87486468a7406 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 511 535 2.0E-29 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS16140 124274f4b74491748cf87486468a7406 793 PRINTS PR00811 Bacterial general secretion pathway protein D signature 669 683 2.0E-29 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS16140 124274f4b74491748cf87486468a7406 793 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 134 691 2.6E-165 T 29-03-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 346 362 1.8E-17 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 370 378 1.8E-17 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 304 313 1.8E-17 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 240 249 1.8E-17 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 276 295 1.8E-17 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 181 191 1.8E-17 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 204 211 1.8E-17 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 Pfam PF00175 Oxidoreductase NAD-binding domain 277 383 4.8E-12 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 Gene3D G3DSA:3.30.70.20 13 51 7.1E-15 T 29-03-2018 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 SUPERFAMILY SSF63380 128 269 6.1E-38 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 PIRSF PIRSF000361 100 416 9.8E-70 T 29-03-2018 IPR015701 Ferredoxin--NADP reductase GO:0016491|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 Pfam PF00970 Oxidoreductase FAD-binding domain 201 264 1.9E-4 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 Gene3D G3DSA:2.40.30.10 132 261 1.4E-29 T 29-03-2018 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 TIGRFAM TIGR03224 benzo_boxA: benzoyl-CoA oxygenase/reductase, BoxA protein 9 416 2.2E-218 T 29-03-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00361+1.14.13.20|MetaCyc: PWY-1361|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 SUPERFAMILY SSF52343 265 416 3.93E-33 T 29-03-2018 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 Gene3D G3DSA:3.30.70.20 52 105 3.2E-5 T 29-03-2018 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 Gene3D G3DSA:3.40.50.80 262 415 1.2E-26 T 29-03-2018 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 PIRSF PIRSF501177 1 416 6.9E-222 T 29-03-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00361+1.14.13.20|MetaCyc: PWY-1361|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 SUPERFAMILY SSF54862 14 69 8.13E-21 T 29-03-2018 CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 Pfam PF00037 4Fe-4S binding domain 15 36 1.8E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS13540 4517e19e5689518e5a5c6a66efe52e00 416 Pfam PF00037 4Fe-4S binding domain 42 64 2.1E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS05325 718fb4361c0e3f4e582e9d133f58338d 462 Pfam PF01926 50S ribosome-binding GTPase 7 153 1.4E-16 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CVS48_RS05325 718fb4361c0e3f4e582e9d133f58338d 462 Gene3D G3DSA:3.40.50.300 1 284 6.0E-25 T 29-03-2018 CVS48_RS05325 718fb4361c0e3f4e582e9d133f58338d 462 Pfam PF11981 Domain of unknown function (DUF3482) 166 451 1.2E-99 T 29-03-2018 IPR021871 Protein of unknown function DUF3482 CVS48_RS05325 718fb4361c0e3f4e582e9d133f58338d 462 SUPERFAMILY SSF52540 4 67 2.58E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05325 718fb4361c0e3f4e582e9d133f58338d 462 SUPERFAMILY SSF52540 97 162 2.58E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS12545 250e354fa91a1b51f0189f60a84de546 155 Pfam PF05425 Copper resistance protein D 47 153 5.4E-14 T 29-03-2018 IPR008457 Copper resistance protein D GO:0016021 CVS48_RS07460 0cdd8724211a305d2c298623004dd06d 376 Gene3D G3DSA:1.10.3090.10 131 373 2.2E-26 T 29-03-2018 CVS48_RS07460 0cdd8724211a305d2c298623004dd06d 376 SUPERFAMILY SSF81891 133 320 1.96E-32 T 29-03-2018 CVS48_RS07460 0cdd8724211a305d2c298623004dd06d 376 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 159 220 3.5E-9 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CVS48_RS07460 0cdd8724211a305d2c298623004dd06d 376 Pfam PF01743 Poly A polymerase head domain 15 133 2.0E-15 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CVS48_RS07460 0cdd8724211a305d2c298623004dd06d 376 Gene3D G3DSA:3.30.460.10 7 130 2.1E-28 T 29-03-2018 CVS48_RS07460 0cdd8724211a305d2c298623004dd06d 376 SUPERFAMILY SSF81301 12 131 8.94E-30 T 29-03-2018 CVS48_RS07460 0cdd8724211a305d2c298623004dd06d 376 PIRSF PIRSF000813 248 376 4.2E-11 T 29-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 CVS48_RS07460 0cdd8724211a305d2c298623004dd06d 376 PIRSF PIRSF000813 13 251 2.1E-112 T 29-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 CVS48_RS27435 a5b091c76f4f3ade201f043e6bcd41c7 249 SUPERFAMILY SSF52402 1 242 2.37E-86 T 29-03-2018 CVS48_RS27435 a5b091c76f4f3ade201f043e6bcd41c7 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CVS48_RS27435 a5b091c76f4f3ade201f043e6bcd41c7 249 PIRSF PIRSF000090 1 249 1.1E-85 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CVS48_RS27435 a5b091c76f4f3ade201f043e6bcd41c7 249 SMART SM00893 23 211 3.4E-68 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS27435 a5b091c76f4f3ade201f043e6bcd41c7 249 Gene3D G3DSA:3.40.50.620 1 248 1.9E-90 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS27435 a5b091c76f4f3ade201f043e6bcd41c7 249 Pfam PF01012 Electron transfer flavoprotein domain 28 206 3.6E-47 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 SUPERFAMILY SSF46785 28 101 1.23E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 87 1.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 71 1.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 SUPERFAMILY SSF48008 121 253 9.68E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 97 3.3E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 Gene3D G3DSA:1.10.10.10 3 99 4.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 Pfam PF07729 FCD domain 122 244 4.6E-25 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 SMART SM00895 119 246 7.0E-20 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 SMART SM00345 38 97 3.1E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS22535 8315893d57aa2a60458b2dddc6bca048 257 Gene3D G3DSA:1.20.120.530 110 257 5.2E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS14875 c2a5938c473b6c426c42e019f456d6fe 123 Pfam PF09842 Predicted membrane protein (DUF2069) 12 114 4.1E-35 T 29-03-2018 IPR018643 Protein of unknown function DUF2069, membrane CVS48_RS07905 c4b9e759ac2a8c261bdd24a9e9671475 208 Gene3D G3DSA:3.40.50.1000 65 208 2.6E-24 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS07905 c4b9e759ac2a8c261bdd24a9e9671475 208 Gene3D G3DSA:3.40.50.1000 1 62 0.064 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS07905 c4b9e759ac2a8c261bdd24a9e9671475 208 SUPERFAMILY SSF56784 2 207 2.8E-40 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS07905 c4b9e759ac2a8c261bdd24a9e9671475 208 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 176 1.3E-29 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS00090 8aed7b8b3e4cf1a67a5e4a9949b73067 257 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 35.013 T 29-03-2018 IPR005583 Peroxide stress protein YaaA CVS48_RS00090 8aed7b8b3e4cf1a67a5e4a9949b73067 257 Pfam PF03883 Peroxide stress protein YaaA 1 242 1.2E-90 T 29-03-2018 IPR005583 Peroxide stress protein YaaA CVS48_RS18560 edbb62a4f91174d42c3956acfc5834cf 457 Pfam PF00753 Metallo-beta-lactamase superfamily 26 198 7.3E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS18560 edbb62a4f91174d42c3956acfc5834cf 457 Gene3D G3DSA:3.60.15.10 8 270 3.2E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS18560 edbb62a4f91174d42c3956acfc5834cf 457 Pfam PF10996 Beta-Casp domain 251 370 1.3E-24 T 29-03-2018 IPR022712 Beta-Casp domain CVS48_RS18560 edbb62a4f91174d42c3956acfc5834cf 457 SMART SM00849 17 235 1.1E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS18560 edbb62a4f91174d42c3956acfc5834cf 457 SUPERFAMILY SSF56281 6 456 3.14E-129 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS18560 edbb62a4f91174d42c3956acfc5834cf 457 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 384 447 1.6E-14 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CVS48_RS18560 edbb62a4f91174d42c3956acfc5834cf 457 SMART SM01027 251 371 3.5E-45 T 29-03-2018 IPR022712 Beta-Casp domain CVS48_RS24230 87dd1461ecfa40249f3421b4c84556e9 225 SUPERFAMILY SSF56235 1 225 1.16E-72 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS24230 87dd1461ecfa40249f3421b4c84556e9 225 Gene3D G3DSA:3.60.20.10 1 217 2.4E-73 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS24230 87dd1461ecfa40249f3421b4c84556e9 225 Pfam PF06267 Family of unknown function (DUF1028) 2 192 4.2E-64 T 29-03-2018 IPR010430 Protein of unknown function DUF1028 CVS48_RS11915 3004a557e20ea8dcfeeb2024672e9f9b 169 SUPERFAMILY SSF109854 5 168 1.56E-57 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CVS48_RS11915 3004a557e20ea8dcfeeb2024672e9f9b 169 Pfam PF09351 Domain of unknown function (DUF1993) 5 166 3.7E-58 T 29-03-2018 IPR018531 Domain of unknown function DUF1993 CVS48_RS11915 3004a557e20ea8dcfeeb2024672e9f9b 169 Gene3D G3DSA:1.20.120.450 2 169 6.6E-63 T 29-03-2018 CVS48_RS21985 6da1e6e71700be5152ab951de152815a 181 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 12 179 7.6E-59 T 29-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria CVS48_RS21985 6da1e6e71700be5152ab951de152815a 181 Pfam PF03350 Uncharacterized protein family, UPF0114 16 132 1.3E-40 T 29-03-2018 IPR005134 Uncharacterised protein family UPF0114 CVS48_RS21985 6da1e6e71700be5152ab951de152815a 181 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 181 89.771 T 29-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria CVS48_RS26410 76d8eaa6e6a78c03ca9e69a535fb808b 269 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 191 266 8.3E-21 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CVS48_RS26410 76d8eaa6e6a78c03ca9e69a535fb808b 269 SUPERFAMILY SSF74653 188 265 3.92E-20 T 29-03-2018 CVS48_RS26410 76d8eaa6e6a78c03ca9e69a535fb808b 269 PRINTS PR01374 Gram-negative bacterial tonB protein signature 185 206 1.9E-9 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 CVS48_RS26410 76d8eaa6e6a78c03ca9e69a535fb808b 269 PRINTS PR01374 Gram-negative bacterial tonB protein signature 206 224 1.9E-9 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 CVS48_RS26410 76d8eaa6e6a78c03ca9e69a535fb808b 269 PRINTS PR01374 Gram-negative bacterial tonB protein signature 122 132 1.9E-9 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 CVS48_RS26410 76d8eaa6e6a78c03ca9e69a535fb808b 269 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 191 267 5.7E-22 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CVS48_RS26410 76d8eaa6e6a78c03ca9e69a535fb808b 269 Gene3D G3DSA:3.30.1150.10 63 269 6.8E-17 T 29-03-2018 CVS48_RS08255 f07ea54a9ea75f9e9e4da178d824de77 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 9.6E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS08255 f07ea54a9ea75f9e9e4da178d824de77 229 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 224 2.2E-92 T 29-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 CVS48_RS08255 f07ea54a9ea75f9e9e4da178d824de77 229 SMART SM00862 149 224 4.5E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS08255 f07ea54a9ea75f9e9e4da178d824de77 229 Gene3D G3DSA:3.40.50.2300 1 126 3.8E-37 T 29-03-2018 CVS48_RS08255 f07ea54a9ea75f9e9e4da178d824de77 229 SMART SM00448 1 111 1.1E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS08255 f07ea54a9ea75f9e9e4da178d824de77 229 SUPERFAMILY SSF52172 1 124 7.4E-41 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS08255 f07ea54a9ea75f9e9e4da178d824de77 229 Gene3D G3DSA:1.10.10.10 127 229 3.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08255 f07ea54a9ea75f9e9e4da178d824de77 229 Pfam PF00072 Response regulator receiver domain 3 111 2.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS08255 f07ea54a9ea75f9e9e4da178d824de77 229 SUPERFAMILY SSF46894 127 225 3.68E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS01240 413babcad2a0e8fdbdf6083dddadeb0c 113 Gene3D G3DSA:2.40.50.140 40 95 1.1E-5 T 29-03-2018 CVS48_RS01240 413babcad2a0e8fdbdf6083dddadeb0c 113 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 36 92 4.3E-9 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CVS48_RS01240 413babcad2a0e8fdbdf6083dddadeb0c 113 SUPERFAMILY SSF50249 4 102 4.97E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS01240 413babcad2a0e8fdbdf6083dddadeb0c 113 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 4 34 2.0E-5 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CVS48_RS16020 3664ff7c3719de7cadb27a7259efa670 234 PIRSF PIRSF000498 1 213 2.5E-55 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS16020 3664ff7c3719de7cadb27a7259efa670 234 SUPERFAMILY SSF63380 94 201 1.28E-26 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS16020 3664ff7c3719de7cadb27a7259efa670 234 Gene3D G3DSA:2.40.30.20 1 93 6.5E-22 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS16020 3664ff7c3719de7cadb27a7259efa670 234 Gene3D G3DSA:2.40.30.20 95 208 7.0E-25 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CVS48_RS16020 3664ff7c3719de7cadb27a7259efa670 234 SUPERFAMILY SSF63380 1 89 5.61E-21 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CVS48_RS16020 3664ff7c3719de7cadb27a7259efa670 234 Pfam PF00677 Lumazine binding domain 3 88 4.0E-17 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS16020 3664ff7c3719de7cadb27a7259efa670 234 Pfam PF00677 Lumazine binding domain 101 186 1.5E-20 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS16020 3664ff7c3719de7cadb27a7259efa670 234 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 201 1.1E-54 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CVS48_RS03155 5c675e17e2fea5b302db9cfc3bbb3bea 79 Pfam PF00550 Phosphopantetheine attachment site 21 74 3.8E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS03155 5c675e17e2fea5b302db9cfc3bbb3bea 79 Gene3D G3DSA:1.10.1200.10 1 79 7.9E-13 T 29-03-2018 CVS48_RS03155 5c675e17e2fea5b302db9cfc3bbb3bea 79 SUPERFAMILY SSF47336 4 77 1.14E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS00840 9fe5575ebc5987636d756e4c0beb9dd5 94 Pfam PF11284 Protein of unknown function (DUF3085) 1 88 1.1E-30 T 29-03-2018 IPR021436 Protein of unknown function DUF3085 CVS48_RS26895 38816a0e387d2530f2c65715169c66cf 42 Pfam PF08085 Entericidin EcnA/B family 21 41 9.2E-10 T 29-03-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 CVS48_RS11235 764f8f7028349690e5925462414724d7 136 Gene3D G3DSA:2.40.50.140 59 124 2.8E-21 T 29-03-2018 CVS48_RS11235 764f8f7028349690e5925462414724d7 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 56 121 1.2E-25 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CVS48_RS11235 764f8f7028349690e5925462414724d7 136 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 19 55 2.8E-12 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CVS48_RS11235 764f8f7028349690e5925462414724d7 136 SUPERFAMILY SSF50249 4 129 8.57E-38 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS24000 ff8bf8a1dc6b00155c3bb5b7a91aff75 199 SMART SM00530 134 189 1.7E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS24000 ff8bf8a1dc6b00155c3bb5b7a91aff75 199 SUPERFAMILY SSF47413 134 189 2.94E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS24000 ff8bf8a1dc6b00155c3bb5b7a91aff75 199 Gene3D G3DSA:1.10.260.40 132 194 1.3E-11 T 29-03-2018 CVS48_RS24000 ff8bf8a1dc6b00155c3bb5b7a91aff75 199 Pfam PF13560 Helix-turn-helix domain 134 190 7.5E-8 T 29-03-2018 CVS48_RS02200 02cc06541d42eb00c81b8f98d671c026 381 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 3 373 3.7E-116 T 29-03-2018 IPR017740 Type VI secretion system-associated, ImpA CVS48_RS02200 02cc06541d42eb00c81b8f98d671c026 381 Pfam PF06812 ImpA, N-terminal, type VI secretion system 9 130 5.3E-39 T 29-03-2018 IPR010657 ImpA, N-terminal CVS48_RS25775 54de193c017d36d7221ed9be3498e80b 337 Pfam PF01339 CheB methylesterase 8 181 2.0E-50 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS25775 54de193c017d36d7221ed9be3498e80b 337 SUPERFAMILY SSF52738 5 187 4.84E-51 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS25775 54de193c017d36d7221ed9be3498e80b 337 PIRSF PIRSF036461 1 332 5.7E-78 T 29-03-2018 IPR011247 Chemotaxis protein-glutamate methylesterase CVS48_RS25775 54de193c017d36d7221ed9be3498e80b 337 Gene3D G3DSA:3.40.50.180 1 192 1.1E-59 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS12315 e0b000b5ac1fbf9bec43c8337f61f5f3 236 Gene3D G3DSA:2.60.120.620 14 236 1.6E-26 T 29-03-2018 CVS48_RS12315 e0b000b5ac1fbf9bec43c8337f61f5f3 236 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 65 235 1.7E-83 T 29-03-2018 IPR018655 Protein of unknown function DUF2086 CVS48_RS23115 8222d4ce1ce94c1ba4b33a931613a0e7 341 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 37 329 2.5E-80 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CVS48_RS23115 8222d4ce1ce94c1ba4b33a931613a0e7 341 Gene3D G3DSA:3.40.718.10 1 338 9.1E-102 T 29-03-2018 CVS48_RS23115 8222d4ce1ce94c1ba4b33a931613a0e7 341 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 5 333 29.763 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CVS48_RS23115 8222d4ce1ce94c1ba4b33a931613a0e7 341 SUPERFAMILY SSF53659 6 334 3.6E-86 T 29-03-2018 CVS48_RS14530 5583b526234915151df4e7a0f77ae184 308 SUPERFAMILY SSF51197 34 290 2.93E-66 T 29-03-2018 CVS48_RS14530 5583b526234915151df4e7a0f77ae184 308 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 21 298 5.2E-150 T 29-03-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 CVS48_RS14530 5583b526234915151df4e7a0f77ae184 308 Gene3D G3DSA:2.60.120.620 21 280 2.2E-47 T 29-03-2018 CVS48_RS14530 5583b526234915151df4e7a0f77ae184 308 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 45 260 2.1E-33 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CVS48_RS13475 1d950d8cf6bf7a996440fcfc10a5df46 230 SUPERFAMILY SSF161098 13 207 1.31E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13475 1d950d8cf6bf7a996440fcfc10a5df46 230 Gene3D G3DSA:1.10.3720.10 2 214 6.4E-46 T 29-03-2018 CVS48_RS13475 1d950d8cf6bf7a996440fcfc10a5df46 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 213 1.1E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13475 1d950d8cf6bf7a996440fcfc10a5df46 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 3.4E-30 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS22530 096d60dd7230df4180685794c38c0bc8 370 Gene3D G3DSA:3.30.1370.60 86 328 7.6E-84 T 29-03-2018 CVS48_RS22530 096d60dd7230df4180685794c38c0bc8 370 Pfam PF02615 Malate/L-lactate dehydrogenase 12 354 8.6E-111 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CVS48_RS22530 096d60dd7230df4180685794c38c0bc8 370 SUPERFAMILY SSF89733 11 365 5.76E-100 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CVS48_RS22530 096d60dd7230df4180685794c38c0bc8 370 Gene3D G3DSA:1.10.1530.10 9 85 7.0E-21 T 29-03-2018 CVS48_RS17275 ff9c11a19068a0275f3c90d9b4d08eec 145 Pfam PF03061 Thioesterase superfamily 53 129 1.1E-14 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CVS48_RS17275 ff9c11a19068a0275f3c90d9b4d08eec 145 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 24 126 1.9E-15 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CVS48_RS17275 ff9c11a19068a0275f3c90d9b4d08eec 145 SUPERFAMILY SSF54637 7 138 5.05E-28 T 29-03-2018 IPR029069 HotDog domain CVS48_RS17275 ff9c11a19068a0275f3c90d9b4d08eec 145 Gene3D G3DSA:3.10.129.10 7 142 6.6E-26 T 29-03-2018 CVS48_RS08060 9f8cb0fa4b35a640f28349066dbc0535 142 SMART SM00530 1 54 1.1E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS08060 9f8cb0fa4b35a640f28349066dbc0535 142 Pfam PF01381 Helix-turn-helix 1 54 1.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS08060 9f8cb0fa4b35a640f28349066dbc0535 142 SUPERFAMILY SSF47413 1 61 3.1E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS08060 9f8cb0fa4b35a640f28349066dbc0535 142 Gene3D G3DSA:1.10.260.40 1 90 1.2E-13 T 29-03-2018 CVS48_RS11465 1ebd588fb84cdea7986e8864fb435e17 208 Gene3D G3DSA:3.40.30.10 2 95 1.3E-21 T 29-03-2018 CVS48_RS11465 1ebd588fb84cdea7986e8864fb435e17 208 SUPERFAMILY SSF47616 134 203 1.53E-15 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS11465 1ebd588fb84cdea7986e8864fb435e17 208 Pfam PF13410 Glutathione S-transferase, C-terminal domain 135 194 3.5E-6 T 29-03-2018 CVS48_RS11465 1ebd588fb84cdea7986e8864fb435e17 208 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 78 1.7E-10 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS11465 1ebd588fb84cdea7986e8864fb435e17 208 Gene3D G3DSA:1.20.1050.10 96 203 1.6E-14 T 29-03-2018 CVS48_RS11465 1ebd588fb84cdea7986e8864fb435e17 208 SUPERFAMILY SSF52833 1 84 1.08E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS07865 90b4076c626d59cb67f53c78f0b18b72 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 253 5.1E-31 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS07865 90b4076c626d59cb67f53c78f0b18b72 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 56 69 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CVS48_RS07865 90b4076c626d59cb67f53c78f0b18b72 338 SMART SM00062 33 263 5.6E-46 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS07865 90b4076c626d59cb67f53c78f0b18b72 338 Gene3D G3DSA:3.40.190.10 136 226 1.2E-14 T 29-03-2018 CVS48_RS07865 90b4076c626d59cb67f53c78f0b18b72 338 Gene3D G3DSA:3.40.190.10 23 135 2.3E-18 T 29-03-2018 CVS48_RS07865 90b4076c626d59cb67f53c78f0b18b72 338 SUPERFAMILY SSF53850 24 257 6.08E-47 T 29-03-2018 CVS48_RS25305 2334eaf262cc417b0575d2c2b8202b31 430 Gene3D G3DSA:3.30.9.10 226 344 2.1E-17 T 29-03-2018 CVS48_RS25305 2334eaf262cc417b0575d2c2b8202b31 430 Gene3D G3DSA:3.50.50.60 6 225 1.3E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS25305 2334eaf262cc417b0575d2c2b8202b31 430 SUPERFAMILY SSF51905 30 254 1.17E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS25305 2334eaf262cc417b0575d2c2b8202b31 430 SUPERFAMILY SSF51905 345 402 1.17E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS25305 2334eaf262cc417b0575d2c2b8202b31 430 Pfam PF01266 FAD dependent oxidoreductase 31 381 7.8E-55 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS09185 a22545e9027a84e57b754da569437dd1 259 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 10 258 3.8E-91 T 29-03-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 CVS48_RS09185 a22545e9027a84e57b754da569437dd1 259 Pfam PF00561 alpha/beta hydrolase fold 22 245 2.4E-26 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS09185 a22545e9027a84e57b754da569437dd1 259 SUPERFAMILY SSF53474 2 258 7.88E-70 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS09185 a22545e9027a84e57b754da569437dd1 259 Gene3D G3DSA:3.40.50.1820 3 259 1.7E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS09185 a22545e9027a84e57b754da569437dd1 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 5.4E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS09185 a22545e9027a84e57b754da569437dd1 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 5.4E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS09185 a22545e9027a84e57b754da569437dd1 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 5.4E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS23835 cb90691e73aaa02381264a7301288707 223 Gene3D G3DSA:1.10.357.10 53 216 1.2E-35 T 29-03-2018 CVS48_RS23835 cb90691e73aaa02381264a7301288707 223 SUPERFAMILY SSF48498 84 218 1.11E-32 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS23835 cb90691e73aaa02381264a7301288707 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS23835 cb90691e73aaa02381264a7301288707 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS23835 cb90691e73aaa02381264a7301288707 223 SUPERFAMILY SSF46689 4 78 4.87E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS23835 cb90691e73aaa02381264a7301288707 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 6.9E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS23835 cb90691e73aaa02381264a7301288707 223 Gene3D G3DSA:1.10.10.60 2 52 1.1E-18 T 29-03-2018 CVS48_RS08555 5575a629fa772f361b4534b7738d41dd 162 Gene3D G3DSA:2.30.110.20 1 161 4.8E-48 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS08555 5575a629fa772f361b4534b7738d41dd 162 Pfam PF05638 Type VI secretion system effector, Hcp 6 146 1.5E-36 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS08555 5575a629fa772f361b4534b7738d41dd 162 SUPERFAMILY SSF141452 2 159 2.88E-41 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS08555 5575a629fa772f361b4534b7738d41dd 162 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 158 6.6E-56 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CVS48_RS28830 2fc0a38e8a0cc66ec2d6bb40937c0b1e 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 270 3.6E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28830 2fc0a38e8a0cc66ec2d6bb40937c0b1e 273 SUPERFAMILY SSF161098 64 251 3.01E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28830 2fc0a38e8a0cc66ec2d6bb40937c0b1e 273 Gene3D G3DSA:1.10.3720.10 6 271 1.8E-40 T 29-03-2018 CVS48_RS16765 1f47ed0fe17987b1019e18409d2c73d4 107 SUPERFAMILY SSF63592 6 99 2.75E-35 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CVS48_RS16765 1f47ed0fe17987b1019e18409d2c73d4 107 Gene3D G3DSA:1.10.4000.10 5 104 1.7E-37 T 29-03-2018 CVS48_RS16765 1f47ed0fe17987b1019e18409d2c73d4 107 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 12 99 4.0E-43 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CVS48_RS16765 1f47ed0fe17987b1019e18409d2c73d4 107 Pfam PF05247 Flagellar transcriptional activator (FlhD) 6 104 1.9E-41 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CVS48_RS16765 1f47ed0fe17987b1019e18409d2c73d4 107 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 3 106 27.76 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CVS48_RS19120 2458fd641e99931ce1931d01ba41f208 541 Pfam PF13598 Domain of unknown function (DUF4139) 210 533 1.4E-63 T 29-03-2018 IPR011935 Conserved hypothetical protein CHP02231 CVS48_RS19120 2458fd641e99931ce1931d01ba41f208 541 Gene3D G3DSA:2.60.40.1220 457 540 0.07 T 29-03-2018 CVS48_RS19120 2458fd641e99931ce1931d01ba41f208 541 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 22 120 2.1E-22 T 29-03-2018 IPR025554 Domain of unknown function DUF4140 CVS48_RS19120 2458fd641e99931ce1931d01ba41f208 541 Gene3D G3DSA:1.20.5.340 76 306 1.2E-7 T 29-03-2018 CVS48_RS19120 2458fd641e99931ce1931d01ba41f208 541 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 19 538 2.6E-144 T 29-03-2018 IPR011935 Conserved hypothetical protein CHP02231 CVS48_RS24280 046be3054c735955a8141353cd129374 221 Pfam PF02586 SOS response associated peptidase (SRAP) 1 220 7.1E-30 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) CVS48_RS24280 046be3054c735955a8141353cd129374 221 Gene3D G3DSA:3.90.1680.10 1 221 5.6E-43 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) CVS48_RS24280 046be3054c735955a8141353cd129374 221 SUPERFAMILY SSF143081 2 220 1.06E-54 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) CVS48_RS11115 023210a65a5b73322058b087320a6f24 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS11115 023210a65a5b73322058b087320a6f24 236 SMART SM00382 29 213 1.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS11115 023210a65a5b73322058b087320a6f24 236 Pfam PF00005 ABC transporter 22 164 7.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS11115 023210a65a5b73322058b087320a6f24 236 Gene3D G3DSA:3.40.50.300 1 233 6.8E-54 T 29-03-2018 CVS48_RS11115 023210a65a5b73322058b087320a6f24 236 SUPERFAMILY SSF52540 4 227 1.36E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26285 f9405b050d150a354c17db6b304e1802 425 PIRSF PIRSF006066 1 425 1.1E-162 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS26285 f9405b050d150a354c17db6b304e1802 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 416 3.1E-131 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS26285 f9405b050d150a354c17db6b304e1802 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 413 2.2E-116 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS28085 9142650f7397e86ceb50823add60be02 542 Gene3D G3DSA:3.50.50.60 1 379 1.2E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS28085 9142650f7397e86ceb50823add60be02 542 SUPERFAMILY SSF51905 301 440 1.99E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS28085 9142650f7397e86ceb50823add60be02 542 SUPERFAMILY SSF51905 1 204 1.99E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS28085 9142650f7397e86ceb50823add60be02 542 SUPERFAMILY SSF54862 442 540 1.73E-27 T 29-03-2018 CVS48_RS28085 9142650f7397e86ceb50823add60be02 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 4.8E-6 T 29-03-2018 CVS48_RS28085 9142650f7397e86ceb50823add60be02 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 173 188 4.8E-6 T 29-03-2018 CVS48_RS28085 9142650f7397e86ceb50823add60be02 542 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 438 540 8.2E-50 T 29-03-2018 CVS48_RS28085 9142650f7397e86ceb50823add60be02 542 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 52 5.7E-6 T 29-03-2018 CVS48_RS28085 9142650f7397e86ceb50823add60be02 542 SUPERFAMILY SSF54373 206 300 1.33E-37 T 29-03-2018 CVS48_RS05510 ae128fe59314b0d9b67353c2e833c058 645 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 19 621 0.0 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 CVS48_RS05510 ae128fe59314b0d9b67353c2e833c058 645 PIRSF PIRSF000719 17 92 2.0E-16 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 CVS48_RS05510 ae128fe59314b0d9b67353c2e833c058 645 PIRSF PIRSF000719 112 627 1.3E-206 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 CVS48_RS05510 ae128fe59314b0d9b67353c2e833c058 645 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 15 623 44.588 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 CVS48_RS05510 ae128fe59314b0d9b67353c2e833c058 645 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 23 619 5.0E-247 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 CVS48_RS23820 a0e8caee99a8ca5c98f25bfdd66fda16 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 199 2.3E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23820 a0e8caee99a8ca5c98f25bfdd66fda16 221 SUPERFAMILY SSF46894 136 206 3.74E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS23820 a0e8caee99a8ca5c98f25bfdd66fda16 221 Gene3D G3DSA:3.40.50.2300 1 124 8.1E-7 T 29-03-2018 CVS48_RS23820 a0e8caee99a8ca5c98f25bfdd66fda16 221 SMART SM00421 143 200 1.5E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23820 a0e8caee99a8ca5c98f25bfdd66fda16 221 SUPERFAMILY SSF52172 3 176 2.72E-9 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS23820 a0e8caee99a8ca5c98f25bfdd66fda16 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23820 a0e8caee99a8ca5c98f25bfdd66fda16 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23820 a0e8caee99a8ca5c98f25bfdd66fda16 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS23820 a0e8caee99a8ca5c98f25bfdd66fda16 221 Gene3D G3DSA:1.10.10.10 125 210 1.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17555 01816ca4334b168021b2d0836026fcff 210 Gene3D G3DSA:1.20.950.20 18 210 2.3E-34 T 29-03-2018 CVS48_RS17555 01816ca4334b168021b2d0836026fcff 210 Pfam PF01292 Prokaryotic cytochrome b561 21 209 5.3E-27 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CVS48_RS17555 01816ca4334b168021b2d0836026fcff 210 SUPERFAMILY SSF81342 20 210 1.41E-34 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CVS48_RS17555 01816ca4334b168021b2d0836026fcff 210 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 23 46 1.6E-5 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 CVS48_RS17555 01816ca4334b168021b2d0836026fcff 210 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 175 197 1.6E-5 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 CVS48_RS18135 32ab37469dec6477ea62b750d8a77521 524 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 114 522 7.7E-145 T 29-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CVS48_RS18135 32ab37469dec6477ea62b750d8a77521 524 SMART SM00858 18 88 1.2E-7 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS18135 32ab37469dec6477ea62b750d8a77521 524 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 11 524 1.0E-274 T 29-03-2018 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 CVS48_RS18135 32ab37469dec6477ea62b750d8a77521 524 Pfam PF08666 SAF domain 18 84 4.6E-8 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS20165 454153f3959d239cfbc48662e1b692ee 475 SUPERFAMILY SSF56954 61 474 6.28E-98 T 29-03-2018 CVS48_RS20165 454153f3959d239cfbc48662e1b692ee 475 SUPERFAMILY SSF56954 6 30 6.28E-98 T 29-03-2018 CVS48_RS20165 454153f3959d239cfbc48662e1b692ee 475 Pfam PF02321 Outer membrane efflux protein 70 261 3.8E-25 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS20165 454153f3959d239cfbc48662e1b692ee 475 Pfam PF02321 Outer membrane efflux protein 292 463 6.4E-20 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS20165 454153f3959d239cfbc48662e1b692ee 475 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 472 3.2E-91 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS20165 454153f3959d239cfbc48662e1b692ee 475 Gene3D G3DSA:1.20.1600.10 20 475 1.9E-90 T 29-03-2018 CVS48_RS22890 d7cc5686d6b08ab2aff995ab8df45ea5 316 Gene3D G3DSA:3.20.20.140 1 313 1.5E-80 T 29-03-2018 CVS48_RS22890 d7cc5686d6b08ab2aff995ab8df45ea5 316 Pfam PF00962 Adenosine/AMP deaminase 8 311 3.5E-70 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CVS48_RS22890 d7cc5686d6b08ab2aff995ab8df45ea5 316 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 8 312 1.0E-106 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CVS48_RS22890 d7cc5686d6b08ab2aff995ab8df45ea5 316 SUPERFAMILY SSF51556 3 312 8.99E-86 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS22890 d7cc5686d6b08ab2aff995ab8df45ea5 316 Hamap MF_01962 Adenine deaminase. 4 316 83.088 T 29-03-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CVS48_RS20105 b4a572de74b7de7bfad7ac7fa724c19e 144 Gene3D G3DSA:2.60.40.1120 37 144 8.0E-7 T 29-03-2018 CVS48_RS10415 83627cab7f36d11eea9b05e3cc3b3f3b 478 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 436 4.1E-166 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CVS48_RS10415 83627cab7f36d11eea9b05e3cc3b3f3b 478 PIRSF PIRSF006446 1 461 9.5E-216 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CVS48_RS15940 67e2a8351d26a3b81ad04d1b43adaeb6 222 Gene3D G3DSA:2.60.120.10 10 121 6.6E-27 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS15940 67e2a8351d26a3b81ad04d1b43adaeb6 222 Pfam PF05962 HutD 12 185 1.4E-33 T 29-03-2018 IPR010282 Uncharacterised protein family HutD/Ves CVS48_RS15940 67e2a8351d26a3b81ad04d1b43adaeb6 222 SUPERFAMILY SSF51182 11 138 6.31E-31 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS14155 9e2598a325fcd606f5a8029f14bcb57d 311 Gene3D G3DSA:3.20.20.70 1 311 1.4E-109 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS14155 9e2598a325fcd606f5a8029f14bcb57d 311 Pfam PF05853 beta-keto acid cleavage enzyme 7 303 2.6E-106 T 29-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CVS48_RS02790 cf42af6fc30b90f8cb9b41c357a990e9 359 SUPERFAMILY SSF53448 43 268 6.25E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS02790 cf42af6fc30b90f8cb9b41c357a990e9 359 Gene3D G3DSA:3.90.550.10 23 251 1.7E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS02790 cf42af6fc30b90f8cb9b41c357a990e9 359 Pfam PF00535 Glycosyl transferase family 2 44 204 7.8E-30 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS05055 06a3012c28d5527e873adf1588b7019f 262 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 22 260 1.6E-80 T 29-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria CVS48_RS05055 06a3012c28d5527e873adf1588b7019f 262 Pfam PF02405 Permease MlaE 47 258 5.2E-74 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CVS48_RS13085 cdd2fbdc7f840f873ac4ae12e8b1a738 514 SUPERFAMILY SSF50475 3 349 1.06E-109 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS13085 cdd2fbdc7f840f873ac4ae12e8b1a738 514 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 458 1.2E-164 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CVS48_RS13085 cdd2fbdc7f840f873ac4ae12e8b1a738 514 Gene3D G3DSA:1.20.5.570 487 514 1.0E-18 T 29-03-2018 CVS48_RS13085 cdd2fbdc7f840f873ac4ae12e8b1a738 514 SUPERFAMILY SSF143968 350 514 2.35E-66 T 29-03-2018 CVS48_RS13085 cdd2fbdc7f840f873ac4ae12e8b1a738 514 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 514 72.676 T 29-03-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CVS48_RS13085 cdd2fbdc7f840f873ac4ae12e8b1a738 514 Gene3D G3DSA:3.40.1670.10 350 486 4.9E-51 T 29-03-2018 CVS48_RS13085 cdd2fbdc7f840f873ac4ae12e8b1a738 514 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 281 1.0E-73 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CVS48_RS13085 cdd2fbdc7f840f873ac4ae12e8b1a738 514 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 305 482 4.0E-75 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 58 3.0E-15 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 1.2E-56 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 Gene3D G3DSA:3.40.50.620 1 158 8.4E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 Pfam PF01467 Cytidylyltransferase-like 5 133 1.1E-19 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.299 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.2E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.2E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.2E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.2E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.2E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CVS48_RS10965 e2585dc8d6dcc05fd935b1e1ae379453 167 SUPERFAMILY SSF52374 1 156 4.83E-44 T 29-03-2018 CVS48_RS28785 177a154503a090909d296b1a23b2b806 217 SUPERFAMILY SSF48498 86 198 6.47E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS28785 177a154503a090909d296b1a23b2b806 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 2.9E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS28785 177a154503a090909d296b1a23b2b806 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.4E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS28785 177a154503a090909d296b1a23b2b806 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.4E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS28785 177a154503a090909d296b1a23b2b806 217 SUPERFAMILY SSF46689 6 86 5.64E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS28785 177a154503a090909d296b1a23b2b806 217 Gene3D G3DSA:1.10.10.60 4 65 3.8E-19 T 29-03-2018 CVS48_RS28785 177a154503a090909d296b1a23b2b806 217 Gene3D G3DSA:1.10.357.10 66 201 1.4E-16 T 29-03-2018 CVS48_RS28785 177a154503a090909d296b1a23b2b806 217 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 87 198 3.8E-9 T 29-03-2018 CVS48_RS05810 daf0994b9cab5266ffa8d704852604c7 348 Gene3D G3DSA:3.40.50.2300 45 160 2.0E-21 T 29-03-2018 CVS48_RS05810 daf0994b9cab5266ffa8d704852604c7 348 Gene3D G3DSA:3.40.50.2300 161 339 5.6E-38 T 29-03-2018 CVS48_RS05810 daf0994b9cab5266ffa8d704852604c7 348 SUPERFAMILY SSF53822 48 245 2.35E-5 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS05810 daf0994b9cab5266ffa8d704852604c7 348 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 61 287 1.4E-38 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CVS48_RS00130 21bfbb2308c6b4529072b383e4731411 204 SUPERFAMILY SSF50475 1 197 1.52E-43 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS00130 21bfbb2308c6b4529072b383e4731411 204 Pfam PF01613 Flavin reductase like domain 22 162 1.2E-17 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS00130 21bfbb2308c6b4529072b383e4731411 204 Gene3D G3DSA:2.30.110.10 5 199 5.4E-44 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS00130 21bfbb2308c6b4529072b383e4731411 204 SMART SM00903 19 173 4.3E-22 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS22545 c98968025030ddbbd01a86c46eb1be44 333 Gene3D G3DSA:3.40.190.10 140 304 7.3E-10 T 29-03-2018 CVS48_RS22545 c98968025030ddbbd01a86c46eb1be44 333 PIRSF PIRSF017082 1 332 8.3E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22545 c98968025030ddbbd01a86c46eb1be44 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 328 1.4E-81 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22545 c98968025030ddbbd01a86c46eb1be44 333 SUPERFAMILY SSF53850 144 288 2.31E-11 T 29-03-2018 CVS48_RS11035 a14e37d33811fd674cf32998ed5e590f 169 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 24 155 4.6E-36 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CVS48_RS11035 a14e37d33811fd674cf32998ed5e590f 169 Gene3D G3DSA:1.10.940.10 19 160 1.4E-34 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CVS48_RS11035 a14e37d33811fd674cf32998ed5e590f 169 SUPERFAMILY SSF48013 22 157 8.9E-36 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CVS48_RS11035 a14e37d33811fd674cf32998ed5e590f 169 Pfam PF01029 NusB family 25 153 5.5E-29 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CVS48_RS11035 a14e37d33811fd674cf32998ed5e590f 169 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 22 157 20.251 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CVS48_RS23060 f0d55cf564115adef317a70a252d360c 165 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 20 134 5.9E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS23060 f0d55cf564115adef317a70a252d360c 165 SUPERFAMILY SSF54593 12 137 9.4E-34 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS23060 f0d55cf564115adef317a70a252d360c 165 Gene3D G3DSA:3.10.180.10 11 148 8.9E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS20140 9492d373816d3cda6b52188820685b1d 147 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 117 1.4E-29 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CVS48_RS20140 9492d373816d3cda6b52188820685b1d 147 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 146 1.3E-36 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CVS48_RS20140 9492d373816d3cda6b52188820685b1d 147 SUPERFAMILY SSF55620 1 145 3.17E-40 T 29-03-2018 CVS48_RS20140 9492d373816d3cda6b52188820685b1d 147 Gene3D G3DSA:3.30.479.10 1 147 3.7E-39 T 29-03-2018 CVS48_RS20140 9492d373816d3cda6b52188820685b1d 147 PIRSF PIRSF006113 1 81 4.7E-18 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CVS48_RS20140 9492d373816d3cda6b52188820685b1d 147 PIRSF PIRSF006113 87 147 0.029 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CVS48_RS18470 f665a82fe9b655a94b9ba261ba90100b 260 Gene3D G3DSA:3.20.20.370 3 250 3.1E-106 T 29-03-2018 CVS48_RS18470 f665a82fe9b655a94b9ba261ba90100b 260 SUPERFAMILY SSF88713 3 251 2.52E-97 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CVS48_RS18470 f665a82fe9b655a94b9ba261ba90100b 260 Pfam PF03746 LamB/YcsF family 4 242 3.6E-100 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CVS48_RS18470 f665a82fe9b655a94b9ba261ba90100b 260 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 45.728 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CVS48_RS15085 6c97a68ae8528a0eb830f6af3a3b37d8 335 Gene3D G3DSA:1.10.3720.10 2 315 2.9E-44 T 29-03-2018 CVS48_RS15085 6c97a68ae8528a0eb830f6af3a3b37d8 335 SUPERFAMILY SSF161098 95 313 4.19E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS15085 6c97a68ae8528a0eb830f6af3a3b37d8 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 325 1.6E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS06700 ac6e20ac544ab5a13df43de7b634dd1b 258 SMART SM00240 25 79 0.0025 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CVS48_RS06700 ac6e20ac544ab5a13df43de7b634dd1b 258 SUPERFAMILY SSF49879 21 111 5.16E-14 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CVS48_RS06700 ac6e20ac544ab5a13df43de7b634dd1b 258 Gene3D G3DSA:2.60.200.20 2 107 5.2E-12 T 29-03-2018 CVS48_RS06700 ac6e20ac544ab5a13df43de7b634dd1b 258 Pfam PF00498 FHA domain 27 96 7.2E-8 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CVS48_RS10340 b8940225ce4cba0ebcf6369dd3286488 179 Gene3D G3DSA:3.40.30.10 22 178 2.5E-33 T 29-03-2018 CVS48_RS10340 b8940225ce4cba0ebcf6369dd3286488 179 Pfam PF00578 AhpC/TSA family 36 156 1.8E-14 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS10340 b8940225ce4cba0ebcf6369dd3286488 179 SUPERFAMILY SSF52833 36 175 3.91E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS00625 7cd9a5d53354db614520c649930276a2 506 Pfam PF07916 TraG-like protein, N-terminal region 10 489 1.2E-96 T 29-03-2018 IPR012931 TraG-like, N-terminal CVS48_RS06980 3aba1c623c877a1de89d31b03091f0ed 298 SUPERFAMILY SSF51735 1 292 8.44E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS06980 3aba1c623c877a1de89d31b03091f0ed 298 Pfam PF04321 RmlD substrate binding domain 1 291 6.7E-100 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CVS48_RS06980 3aba1c623c877a1de89d31b03091f0ed 298 Gene3D G3DSA:3.40.50.720 1 195 4.5E-24 T 29-03-2018 CVS48_RS06980 3aba1c623c877a1de89d31b03091f0ed 298 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 290 3.3E-97 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CVS48_RS06980 3aba1c623c877a1de89d31b03091f0ed 298 Gene3D G3DSA:3.90.25.10 196 278 2.5E-18 T 29-03-2018 CVS48_RS02185 9b4f9e989c67f4381620dd967777a371 1253 Pfam PF06761 Intracellular multiplication and human macrophage-killing 485 840 1.5E-88 T 29-03-2018 IPR009612 ImcF-related CVS48_RS02185 9b4f9e989c67f4381620dd967777a371 1253 Gene3D G3DSA:3.40.50.300 78 398 6.5E-7 T 29-03-2018 CVS48_RS02185 9b4f9e989c67f4381620dd967777a371 1253 SUPERFAMILY SSF52540 116 266 1.26E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS02185 9b4f9e989c67f4381620dd967777a371 1253 Pfam PF14331 ImcF-related N-terminal domain 181 432 1.0E-79 T 29-03-2018 IPR025743 ImcF-related, N-terminal domain CVS48_RS02185 9b4f9e989c67f4381620dd967777a371 1253 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 23 1207 1.2E-214 T 29-03-2018 IPR017731 Type VI secretion system, IcmF CVS48_RS02185 9b4f9e989c67f4381620dd967777a371 1253 Pfam PF06744 Type VI secretion protein IcmF C-terminal 976 1177 1.1E-49 T 29-03-2018 IPR010623 Type VI secretion system IcmF, C-terminal CVS48_RS11785 2e4f9836d4ed1e4dc30a3691504948b6 149 Pfam PF13441 YMGG-like Gly-zipper 59 120 4.4E-8 T 29-03-2018 IPR027367 YMGG-like Gly-zipper CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 PIRSF PIRSF001554 1 386 6.2E-153 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 SUPERFAMILY SSF56059 1 238 1.94E-83 T 29-03-2018 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 Pfam PF00549 CoA-ligase 262 381 2.8E-25 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 8.5E-159 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.797 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 Gene3D G3DSA:3.30.470.20 96 239 2.2E-55 T 29-03-2018 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 Gene3D G3DSA:3.30.1490.20 21 95 3.1E-25 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 Gene3D G3DSA:3.40.50.261 240 385 6.5E-45 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 SUPERFAMILY SSF52210 239 385 5.1E-54 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CVS48_RS26820 8645463d6482edcc33778e7bc4b5446a 386 Pfam PF08442 ATP-grasp domain 2 201 2.0E-79 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 3.4E-8 T 29-03-2018 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 3.4E-8 T 29-03-2018 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 313 320 3.4E-8 T 29-03-2018 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 Gene3D G3DSA:3.50.50.60 142 351 5.7E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 4.4E-19 T 29-03-2018 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 320 4.4E-19 T 29-03-2018 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 4.4E-19 T 29-03-2018 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 4.4E-19 T 29-03-2018 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 341 1.9E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 Gene3D G3DSA:3.50.50.60 3 141 7.1E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS11060 414c732ea2fa906fc89a6cd2269de749 439 SUPERFAMILY SSF51905 3 347 1.45E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21855 1bbe0755f3ada5821cf72ab4eda5e772 345 Gene3D G3DSA:1.10.3470.10 3 325 1.2E-33 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS21855 1bbe0755f3ada5821cf72ab4eda5e772 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 320 3.9E-34 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS29055 02dd2e99386c42afb3fc0e4c7aaa7b79 402 Pfam PF02515 CoA-transferase family III 17 378 7.2E-99 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS29055 02dd2e99386c42afb3fc0e4c7aaa7b79 402 SUPERFAMILY SSF89796 13 401 1.02E-111 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS29055 02dd2e99386c42afb3fc0e4c7aaa7b79 402 Gene3D G3DSA:3.40.50.10540 11 402 4.0E-115 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS25170 6aa0571e1e24350c833159d9cfd915b5 233 Gene3D G3DSA:2.60.130.10 2 233 1.3E-65 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CVS48_RS25170 6aa0571e1e24350c833159d9cfd915b5 233 Pfam PF00775 Dioxygenase 45 226 1.9E-56 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CVS48_RS25170 6aa0571e1e24350c833159d9cfd915b5 233 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 16 233 1.0E-105 T 29-03-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CVS48_RS25170 6aa0571e1e24350c833159d9cfd915b5 233 SUPERFAMILY SSF49482 12 232 2.88E-76 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CVS48_RS25170 6aa0571e1e24350c833159d9cfd915b5 233 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 77 105 - T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CVS48_RS25170 6aa0571e1e24350c833159d9cfd915b5 233 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 7 41 1.3E-11 T 29-03-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 73 3.9E-32 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 SUPERFAMILY SSF46557 4 78 8.76E-28 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 1.2E-28 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 PIRSF PIRSF006092 1 158 2.1E-52 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.808 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 SUPERFAMILY SSF54534 83 157 2.22E-23 T 29-03-2018 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 Gene3D G3DSA:1.10.287.180 3 76 2.3E-32 T 29-03-2018 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 9.0E-57 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CVS48_RS13840 0844d99c3cf22d516e819fd986196701 158 Gene3D G3DSA:3.10.50.30 78 158 4.5E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CVS48_RS19385 f0d50d33715dba0b3439b64a71092801 549 SUPERFAMILY SSF53649 305 477 1.55E-17 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS19385 f0d50d33715dba0b3439b64a71092801 549 Pfam PF00884 Sulfatase 256 504 1.4E-19 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CVS48_RS19385 f0d50d33715dba0b3439b64a71092801 549 Gene3D G3DSA:3.40.720.10 251 537 7.0E-16 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS21300 91e1e131ef7eb21d9e98908ecc07462e 177 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 41 171 2.6E-32 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS01365 903aac08f818e914f512bcb6e6323b93 290 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 31 264 7.5E-51 T 29-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 SUPERFAMILY SSF51445 31 243 8.61E-17 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 Gene3D G3DSA:2.60.40.10 423 519 1.9E-28 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 Gene3D G3DSA:2.60.40.1180 987 1079 4.4E-15 T 29-03-2018 CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 SUPERFAMILY SSF51445 603 983 4.06E-89 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 Gene3D G3DSA:3.20.20.80 619 986 3.0E-62 T 29-03-2018 CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 Pfam PF11896 Domain of unknown function (DUF3416) 425 617 4.9E-52 T 29-03-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 SMART SM00642 627 976 4.0E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 422 1078 45.774 T 29-03-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 Gene3D G3DSA:3.20.20.80 22 351 7.1E-14 T 29-03-2018 CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 Gene3D G3DSA:1.20.58.280 520 597 1.1E-13 T 29-03-2018 CVS48_RS18395 1ccf5ea86fa325df0266c6207936188c 1080 Pfam PF00128 Alpha amylase, catalytic domain 641 754 6.8E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CVS48_RS28015 bc10313e181f1ffae8ef2c4367844ac3 377 Gene3D G3DSA:3.30.420.10 126 328 4.9E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS28015 bc10313e181f1ffae8ef2c4367844ac3 377 Pfam PF13518 Helix-turn-helix domain 12 62 6.5E-12 T 29-03-2018 CVS48_RS28015 bc10313e181f1ffae8ef2c4367844ac3 377 Gene3D G3DSA:1.10.10.10 10 65 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS28015 bc10313e181f1ffae8ef2c4367844ac3 377 Pfam PF00665 Integrase core domain 134 257 1.9E-25 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS28015 bc10313e181f1ffae8ef2c4367844ac3 377 SUPERFAMILY SSF46689 11 115 2.15E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS28015 bc10313e181f1ffae8ef2c4367844ac3 377 SUPERFAMILY SSF53098 130 302 2.53E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS15520 fda0e68bef9af106ae204c7bc61592d3 221 SUPERFAMILY SSF52218 9 211 8.38E-29 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS15520 fda0e68bef9af106ae204c7bc61592d3 221 Gene3D G3DSA:3.40.50.360 4 199 2.8E-26 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS15520 fda0e68bef9af106ae204c7bc61592d3 221 Pfam PF03358 NADPH-dependent FMN reductase 9 133 5.4E-17 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CVS48_RS28885 4410fec623487a18e24a4ea79bfb4e3a 446 Pfam PF03600 Citrate transporter 14 387 3.6E-51 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CVS48_RS28885 4410fec623487a18e24a4ea79bfb4e3a 446 TIGRFAM TIGR00784 citMHS: citrate transporter 2 438 1.9E-188 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 CVS48_RS06260 856e6e3b8ca29370d34680426edf5193 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.443 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CVS48_RS06260 856e6e3b8ca29370d34680426edf5193 233 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 6.6E-50 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CVS48_RS06260 856e6e3b8ca29370d34680426edf5193 233 Gene3D G3DSA:3.30.190.20 150 228 2.0E-18 T 29-03-2018 CVS48_RS06260 856e6e3b8ca29370d34680426edf5193 233 PIRSF PIRSF002155 1 227 1.3E-76 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06260 856e6e3b8ca29370d34680426edf5193 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06260 856e6e3b8ca29370d34680426edf5193 233 Gene3D G3DSA:3.40.50.790 68 149 6.4E-36 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CVS48_RS06260 856e6e3b8ca29370d34680426edf5193 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 1.6E-102 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CVS48_RS06260 856e6e3b8ca29370d34680426edf5193 233 SUPERFAMILY SSF56808 6 225 2.35E-81 T 29-03-2018 IPR023674 Ribosomal protein L1-like CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 ProSitePatterns PS00480 Citrate synthase signature. 279 291 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 PRINTS PR00143 Citrate synthase signature 272 292 2.1E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 PRINTS PR00143 Citrate synthase signature 349 363 2.1E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 PRINTS PR00143 Citrate synthase signature 329 345 2.1E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 PRINTS PR00143 Citrate synthase signature 197 212 2.1E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 PRINTS PR00143 Citrate synthase signature 147 160 2.1E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 PRINTS PR00143 Citrate synthase signature 219 247 2.1E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 PIRSF PIRSF001369 23 397 5.5E-110 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 29 396 1.0E-156 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 Gene3D G3DSA:1.10.580.10 36 376 9.2E-80 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 SUPERFAMILY SSF48256 29 396 7.2E-122 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS27930 f5ed0e6a9b48a38296efb9213032425b 397 Pfam PF00285 Citrate synthase, C-terminal domain 30 379 1.5E-112 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS22670 0ff01af909478e78cd8744f625d5ed83 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 313 4.0E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22670 0ff01af909478e78cd8744f625d5ed83 318 SUPERFAMILY SSF53850 108 280 5.07E-5 T 29-03-2018 CVS48_RS22670 0ff01af909478e78cd8744f625d5ed83 318 Gene3D G3DSA:3.40.190.10 53 228 0.0012 T 29-03-2018 CVS48_RS22670 0ff01af909478e78cd8744f625d5ed83 318 PIRSF PIRSF017082 1 318 1.2E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04960 85064fe86abef42803b00e0e1ad4902c 291 Gene3D G3DSA:1.20.120.80 80 291 3.8E-71 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04960 85064fe86abef42803b00e0e1ad4902c 291 Pfam PF00510 Cytochrome c oxidase subunit III 15 291 4.5E-58 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04960 85064fe86abef42803b00e0e1ad4902c 291 Gene3D G3DSA:1.10.287.70 9 79 1.7E-14 T 29-03-2018 CVS48_RS04960 85064fe86abef42803b00e0e1ad4902c 291 SUPERFAMILY SSF81452 13 290 3.24E-78 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 Gene3D G3DSA:3.40.50.300 43 213 1.9E-30 T 29-03-2018 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 Hamap MF_00109 Shikimate kinase [aroK]. 41 207 28.857 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 ProSitePatterns PS01128 Shikimate kinase signature. 97 122 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 PRINTS PR01100 Shikimate kinase family signature 68 81 8.3E-25 T 29-03-2018 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 PRINTS PR01100 Shikimate kinase family signature 114 123 8.3E-25 T 29-03-2018 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 PRINTS PR01100 Shikimate kinase family signature 135 152 8.3E-25 T 29-03-2018 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 PRINTS PR01100 Shikimate kinase family signature 96 104 8.3E-25 T 29-03-2018 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 PRINTS PR01100 Shikimate kinase family signature 44 59 8.3E-25 T 29-03-2018 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 Pfam PF01202 Shikimate kinase 50 206 5.5E-50 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CVS48_RS06760 8a7c793723dcce20b96aabc8326da877 213 SUPERFAMILY SSF52540 44 203 1.32E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS25450 93d93d06663d621cdd7033060565a367 565 Gene3D G3DSA:2.40.160.10 100 565 4.5E-36 T 29-03-2018 CVS48_RS25450 93d93d06663d621cdd7033060565a367 565 SUPERFAMILY SSF56935 408 536 5.13E-7 T 29-03-2018 CVS48_RS25450 93d93d06663d621cdd7033060565a367 565 SUPERFAMILY SSF56935 185 360 5.13E-7 T 29-03-2018 CVS48_RS25450 93d93d06663d621cdd7033060565a367 565 Pfam PF16930 Putative porin 32 565 2.0E-216 T 29-03-2018 IPR032638 Putative bacterial porin CVS48_RS23615 083911c3d93d07dac71389e4566e1715 162 Pfam PF07811 TadE-like protein 18 60 1.5E-7 T 29-03-2018 IPR012495 TadE-like CVS48_RS01030 4f1621e6219e643886fd08fb4a109185 129 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 34 7.0E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS01030 4f1621e6219e643886fd08fb4a109185 129 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS01030 4f1621e6219e643886fd08fb4a109185 129 Gene3D G3DSA:3.30.700.10 15 127 3.7E-16 T 29-03-2018 CVS48_RS01030 4f1621e6219e643886fd08fb4a109185 129 SUPERFAMILY SSF54523 15 101 1.31E-19 T 29-03-2018 CVS48_RS01030 4f1621e6219e643886fd08fb4a109185 129 PRINTS PR00813 Bacterial general secretion pathway protein G signature 14 39 1.4E-11 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CVS48_RS01030 4f1621e6219e643886fd08fb4a109185 129 PRINTS PR00813 Bacterial general secretion pathway protein G signature 50 68 1.4E-11 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CVS48_RS01030 4f1621e6219e643886fd08fb4a109185 129 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 34 1.0E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 ProSitePatterns PS00079 Multicopper oxidases signature 1. 573 593 - T 29-03-2018 IPR033138 Multicopper oxidases, conserved site CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 SUPERFAMILY SSF49503 37 189 1.51E-40 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 Pfam PF00394 Multicopper oxidase 176 351 1.1E-30 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 Pfam PF07732 Multicopper oxidase 56 166 4.6E-42 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 Gene3D G3DSA:2.60.40.420 377 596 6.0E-52 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 SUPERFAMILY SSF49503 440 595 2.42E-40 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 4 596 1.4E-284 T 29-03-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 ProSitePatterns PS00080 Multicopper oxidases signature 2. 578 589 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 SUPERFAMILY SSF49503 170 379 6.1E-56 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 Gene3D G3DSA:2.60.40.420 24 164 1.8E-34 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 Pfam PF07731 Multicopper oxidase 479 595 2.2E-26 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 Gene3D G3DSA:2.60.40.420 171 376 4.1E-39 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS03770 08724914f36b23d27f52f767fdcbe66d 596 ProSitePatterns PS00079 Multicopper oxidases signature 1. 141 161 - T 29-03-2018 IPR033138 Multicopper oxidases, conserved site CVS48_RS05655 cd9586fa21909537e0b1479f23396454 153 Pfam PF13560 Helix-turn-helix domain 34 85 2.6E-8 T 29-03-2018 CVS48_RS05655 cd9586fa21909537e0b1479f23396454 153 SUPERFAMILY SSF47413 33 92 3.49E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS05655 cd9586fa21909537e0b1479f23396454 153 SMART SM00530 33 90 2.1E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS05655 cd9586fa21909537e0b1479f23396454 153 TIGRFAM TIGR02612 mob_myst_A: mobile mystery protein A 7 152 1.8E-40 T 29-03-2018 IPR013435 Mobile mystery protein A CVS48_RS05655 cd9586fa21909537e0b1479f23396454 153 Gene3D G3DSA:1.10.260.40 7 112 5.1E-12 T 29-03-2018 CVS48_RS01325 454bca34527d19e2e54506830324f06c 498 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 172 180 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CVS48_RS01325 454bca34527d19e2e54506830324f06c 498 SMART SM00487 36 241 1.4E-61 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CVS48_RS01325 454bca34527d19e2e54506830324f06c 498 Gene3D G3DSA:3.40.50.300 22 242 4.6E-62 T 29-03-2018 CVS48_RS01325 454bca34527d19e2e54506830324f06c 498 Pfam PF00271 Helicase conserved C-terminal domain 253 358 4.1E-28 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS01325 454bca34527d19e2e54506830324f06c 498 SMART SM00490 277 358 7.8E-34 T 29-03-2018 IPR001650 Helicase, C-terminal CVS48_RS01325 454bca34527d19e2e54506830324f06c 498 Pfam PF00270 DEAD/DEAH box helicase 41 215 6.7E-51 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CVS48_RS01325 454bca34527d19e2e54506830324f06c 498 SUPERFAMILY SSF52540 93 379 2.64E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01325 454bca34527d19e2e54506830324f06c 498 Gene3D G3DSA:3.40.50.300 243 451 8.9E-47 T 29-03-2018 CVS48_RS08035 29944ac23b04cdddd8ee5906a41efb81 382 SMART SM00267 189 361 8.3E-51 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS08035 29944ac23b04cdddd8ee5906a41efb81 382 Pfam PF00990 Diguanylate cyclase, GGDEF domain 200 355 3.2E-42 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS08035 29944ac23b04cdddd8ee5906a41efb81 382 SUPERFAMILY SSF55073 205 360 5.26E-43 T 29-03-2018 IPR029787 Nucleotide cyclase CVS48_RS08035 29944ac23b04cdddd8ee5906a41efb81 382 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 198 356 1.2E-39 T 29-03-2018 IPR000160 GGDEF domain CVS48_RS08035 29944ac23b04cdddd8ee5906a41efb81 382 Gene3D G3DSA:3.30.70.270 193 368 1.2E-51 T 29-03-2018 CVS48_RS06690 ceff0385a8d2f2a7c06fdf2269b677c4 368 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 32 330 5.3E-103 T 29-03-2018 IPR010732 Type VI secretion, TssG-like CVS48_RS06690 ceff0385a8d2f2a7c06fdf2269b677c4 368 Pfam PF06996 Type VI secretion, TssG 32 330 1.7E-103 T 29-03-2018 IPR010732 Type VI secretion, TssG-like CVS48_RS23785 3cb97be0cdb6d184f9d4f49d0d0ed4da 300 Gene3D G3DSA:3.90.550.10 3 265 1.8E-41 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS23785 3cb97be0cdb6d184f9d4f49d0d0ed4da 300 SUPERFAMILY SSF53448 31 232 6.61E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS23785 3cb97be0cdb6d184f9d4f49d0d0ed4da 300 Pfam PF00535 Glycosyl transferase family 2 34 190 4.6E-27 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 7.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 7.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 7.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 7.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 SUPERFAMILY SSF51735 6 254 5.84E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 6.1E-61 T 29-03-2018 CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 2.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 Gene3D G3DSA:3.40.50.720 45 255 1.1E-60 T 29-03-2018 CVS48_RS14115 6edd257cbd8048497eec1c57133efb9b 255 Gene3D G3DSA:3.40.50.720 1 44 1.2E-6 T 29-03-2018 CVS48_RS19190 cee3d131c8bee3b46756e693900b5ad0 273 Gene3D G3DSA:3.40.190.10 32 128 8.9E-14 T 29-03-2018 CVS48_RS19190 cee3d131c8bee3b46756e693900b5ad0 273 Pfam PF03180 NLPA lipoprotein 34 266 1.9E-68 T 29-03-2018 IPR004872 Lipoprotein NlpA family CVS48_RS19190 cee3d131c8bee3b46756e693900b5ad0 273 SUPERFAMILY SSF53850 34 273 1.75E-66 T 29-03-2018 CVS48_RS19190 cee3d131c8bee3b46756e693900b5ad0 273 Gene3D G3DSA:3.40.190.10 129 270 8.1E-38 T 29-03-2018 CVS48_RS00725 304cfda90b256d31a4077304fa87f839 166 SUPERFAMILY SSF56019 6 164 1.57E-27 T 29-03-2018 IPR003511 HORMA domain CVS48_RS00725 304cfda90b256d31a4077304fa87f839 166 Gene3D G3DSA:3.30.900.10 8 153 2.3E-5 T 29-03-2018 CVS48_RS00730 6af9faea32e1fe9c7e5ddf51787fc978 300 Gene3D G3DSA:1.10.1410.20 157 287 6.5E-5 T 29-03-2018 CVS48_RS00730 6af9faea32e1fe9c7e5ddf51787fc978 300 SUPERFAMILY SSF81301 3 156 2.29E-20 T 29-03-2018 CVS48_RS00730 6af9faea32e1fe9c7e5ddf51787fc978 300 Pfam PF01909 Nucleotidyltransferase domain 31 74 4.1E-5 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CVS48_RS00730 6af9faea32e1fe9c7e5ddf51787fc978 300 Gene3D G3DSA:3.30.460.10 18 156 2.8E-16 T 29-03-2018 CVS48_RS12520 45e7246e7d8007219d174efac13641d9 416 Gene3D G3DSA:3.40.640.10 41 295 1.3E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS12520 45e7246e7d8007219d174efac13641d9 416 TIGRFAM TIGR01814 kynureninase: kynureninase 9 400 3.3E-100 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CVS48_RS12520 45e7246e7d8007219d174efac13641d9 416 PIRSF PIRSF038800 1 407 5.5E-144 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CVS48_RS12520 45e7246e7d8007219d174efac13641d9 416 Gene3D G3DSA:3.90.1150.10 296 416 2.0E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS12520 45e7246e7d8007219d174efac13641d9 416 SUPERFAMILY SSF53383 3 400 6.04E-81 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS12520 45e7246e7d8007219d174efac13641d9 416 Hamap MF_01970 Kynureninase [kynU]. 1 399 34.13 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CVS48_RS12520 45e7246e7d8007219d174efac13641d9 416 Pfam PF00266 Aminotransferase class-V 82 350 1.7E-13 T 29-03-2018 IPR000192 Aminotransferase class V domain CVS48_RS17075 850405b612d01def1834d4404647ed31 279 SUPERFAMILY SSF110997 202 276 3.79E-14 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS17075 850405b612d01def1834d4404647ed31 279 Gene3D G3DSA:3.30.70.1070 198 279 3.9E-17 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS17075 850405b612d01def1834d4404647ed31 279 Pfam PF05036 Sporulation related domain 201 276 2.7E-17 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS01450 e4536e7461f1dee307de9db09ee9a33b 233 SUPERFAMILY SSF46894 136 231 3.12E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS01450 e4536e7461f1dee307de9db09ee9a33b 233 Gene3D G3DSA:1.10.10.10 131 233 1.2E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01450 e4536e7461f1dee307de9db09ee9a33b 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 2.3E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS01450 e4536e7461f1dee307de9db09ee9a33b 233 Pfam PF00072 Response regulator receiver domain 9 118 2.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS01450 e4536e7461f1dee307de9db09ee9a33b 233 Gene3D G3DSA:3.40.50.2300 1 130 2.4E-39 T 29-03-2018 CVS48_RS01450 e4536e7461f1dee307de9db09ee9a33b 233 SMART SM00862 154 231 7.9E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS01450 e4536e7461f1dee307de9db09ee9a33b 233 SUPERFAMILY SSF52172 4 129 6.97E-41 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS01450 e4536e7461f1dee307de9db09ee9a33b 233 SMART SM00448 6 117 5.9E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS11325 d949aba9e9fce9fbbcdc21c6da5c3b45 354 SMART SM00829 10 330 6.5E-28 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS11325 d949aba9e9fce9fbbcdc21c6da5c3b45 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 94 1.1E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS11325 d949aba9e9fce9fbbcdc21c6da5c3b45 354 Gene3D G3DSA:3.90.180.10 1 135 2.0E-36 T 29-03-2018 CVS48_RS11325 d949aba9e9fce9fbbcdc21c6da5c3b45 354 SUPERFAMILY SSF50129 1 141 8.07E-33 T 29-03-2018 IPR011032 GroES-like CVS48_RS11325 d949aba9e9fce9fbbcdc21c6da5c3b45 354 Gene3D G3DSA:3.40.50.720 136 316 2.8E-36 T 29-03-2018 CVS48_RS11325 d949aba9e9fce9fbbcdc21c6da5c3b45 354 SUPERFAMILY SSF51735 113 270 1.09E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11325 d949aba9e9fce9fbbcdc21c6da5c3b45 354 Pfam PF00107 Zinc-binding dehydrogenase 152 267 3.3E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS15475 fc4d5be7296bf3c60e28fe4b1446d3e8 86 SUPERFAMILY SSF47336 2 83 2.49E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS15475 fc4d5be7296bf3c60e28fe4b1446d3e8 86 Pfam PF00550 Phosphopantetheine attachment site 7 80 1.1E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS15475 fc4d5be7296bf3c60e28fe4b1446d3e8 86 Gene3D G3DSA:1.10.1200.10 2 85 7.5E-15 T 29-03-2018 CVS48_RS27405 f42e2102df85013ab467f88c0ec8cb24 213 Gene3D G3DSA:3.40.30.10 1 152 2.4E-42 T 29-03-2018 CVS48_RS27405 f42e2102df85013ab467f88c0ec8cb24 213 PIRSF PIRSF000239 1 210 3.7E-79 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS27405 f42e2102df85013ab467f88c0ec8cb24 213 SUPERFAMILY SSF52833 4 210 2.04E-69 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS27405 f42e2102df85013ab467f88c0ec8cb24 213 Pfam PF00578 AhpC/TSA family 7 136 1.8E-33 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS27405 f42e2102df85013ab467f88c0ec8cb24 213 Gene3D G3DSA:3.30.1020.10 153 213 2.6E-24 T 29-03-2018 CVS48_RS27405 f42e2102df85013ab467f88c0ec8cb24 213 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 157 192 1.3E-11 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS01100 f529e533ea500b6cfb73815eb6aedebf 142 Pfam PF13470 PIN domain 5 115 2.9E-21 T 29-03-2018 IPR002716 PIN domain CVS48_RS01100 f529e533ea500b6cfb73815eb6aedebf 142 SUPERFAMILY SSF88723 5 120 9.25E-14 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS01100 f529e533ea500b6cfb73815eb6aedebf 142 SMART SM00670 4 119 6.4E-7 T 29-03-2018 IPR002716 PIN domain CVS48_RS01100 f529e533ea500b6cfb73815eb6aedebf 142 Gene3D G3DSA:3.40.50.1010 1 142 1.8E-13 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS01100 f529e533ea500b6cfb73815eb6aedebf 142 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 5 119 1.0E-18 T 29-03-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component CVS48_RS21680 d9128b85b40a96f3a6678e8c7a580fc4 168 Gene3D G3DSA:2.60.120.10 13 153 1.2E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS21680 d9128b85b40a96f3a6678e8c7a580fc4 168 Pfam PF12973 ChrR Cupin-like domain 25 108 4.8E-7 T 29-03-2018 IPR025979 ChrR-like cupin domain CVS48_RS21680 d9128b85b40a96f3a6678e8c7a580fc4 168 SUPERFAMILY SSF51182 14 108 5.7E-19 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS12400 76f1e97e20f10cc0eeda977e5d1c3b02 434 Pfam PF01546 Peptidase family M20/M25/M40 108 425 2.4E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS12400 76f1e97e20f10cc0eeda977e5d1c3b02 434 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 31 414 2.0E-86 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CVS48_RS12400 76f1e97e20f10cc0eeda977e5d1c3b02 434 SUPERFAMILY SSF55031 215 323 7.5E-12 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS12400 76f1e97e20f10cc0eeda977e5d1c3b02 434 SUPERFAMILY SSF53187 345 429 1.49E-57 T 29-03-2018 CVS48_RS12400 76f1e97e20f10cc0eeda977e5d1c3b02 434 SUPERFAMILY SSF53187 16 214 1.49E-57 T 29-03-2018 CVS48_RS12400 76f1e97e20f10cc0eeda977e5d1c3b02 434 Pfam PF07687 Peptidase dimerisation domain 212 322 2.7E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS12400 76f1e97e20f10cc0eeda977e5d1c3b02 434 Gene3D G3DSA:3.40.630.10 6 324 3.8E-59 T 29-03-2018 CVS48_RS03550 99bbf788e599e76bad4fff37c04c5f06 421 Gene3D G3DSA:2.40.50.100 89 161 2.1E-17 T 29-03-2018 CVS48_RS03550 99bbf788e599e76bad4fff37c04c5f06 421 Pfam PF13437 HlyD family secretion protein 201 303 1.0E-5 T 29-03-2018 CVS48_RS03550 99bbf788e599e76bad4fff37c04c5f06 421 Pfam PF13533 Biotin-lipoyl like 90 135 2.7E-14 T 29-03-2018 CVS48_RS03550 99bbf788e599e76bad4fff37c04c5f06 421 Gene3D G3DSA:2.40.50.100 191 379 1.4E-4 T 29-03-2018 CVS48_RS03550 99bbf788e599e76bad4fff37c04c5f06 421 SUPERFAMILY SSF111369 79 317 1.57E-58 T 29-03-2018 CVS48_RS03550 99bbf788e599e76bad4fff37c04c5f06 421 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 65 393 1.6E-75 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS09330 7603e4a66ac677419f46e17d7af08a28 445 Gene3D G3DSA:3.40.50.720 10 214 2.6E-24 T 29-03-2018 CVS48_RS09330 7603e4a66ac677419f46e17d7af08a28 445 SMART SM00858 361 426 2.4E-5 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CVS48_RS09330 7603e4a66ac677419f46e17d7af08a28 445 SUPERFAMILY SSF51735 14 150 9.98E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS01705 f1e0d28e9063d00917e107f5030e2b5a 652 SMART SM00382 34 221 1.1E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS01705 f1e0d28e9063d00917e107f5030e2b5a 652 Pfam PF00005 ABC transporter 25 173 6.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS01705 f1e0d28e9063d00917e107f5030e2b5a 652 Pfam PF02687 FtsX-like permease family 556 645 4.4E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CVS48_RS01705 f1e0d28e9063d00917e107f5030e2b5a 652 Pfam PF12704 MacB-like periplasmic core domain 275 494 1.8E-40 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CVS48_RS01705 f1e0d28e9063d00917e107f5030e2b5a 652 Gene3D G3DSA:3.40.50.300 2 242 3.9E-65 T 29-03-2018 CVS48_RS01705 f1e0d28e9063d00917e107f5030e2b5a 652 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS01705 f1e0d28e9063d00917e107f5030e2b5a 652 SUPERFAMILY SSF52540 5 229 5.1E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 258 312 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 256 277 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 302 317 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 8.9E-122 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 Gene3D G3DSA:1.20.210.10 26 535 1.9E-222 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 31 534 5.8E-216 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 39 480 5.3E-155 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04970 d9b90c28df190dd84f52ce2b2b2b83ab 535 SUPERFAMILY SSF81442 27 534 2.09E-195 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS22605 4f8033996aae3a17e8e1c2b9c598744b 267 Gene3D G3DSA:3.90.850.10 1 267 2.2E-47 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS22605 4f8033996aae3a17e8e1c2b9c598744b 267 SUPERFAMILY SSF56529 2 266 6.28E-77 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS22605 4f8033996aae3a17e8e1c2b9c598744b 267 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 266 3.4E-134 T 29-03-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 CVS48_RS22605 4f8033996aae3a17e8e1c2b9c598744b 267 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 86 264 3.4E-8 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS20170 32700a0a48b16c1617cd7f7f7ed693ec 288 Gene3D G3DSA:3.30.1980.10 39 123 7.8E-7 T 29-03-2018 CVS48_RS20170 32700a0a48b16c1617cd7f7f7ed693ec 288 Gene3D G3DSA:3.30.1980.10 200 281 0.0013 T 29-03-2018 CVS48_RS01015 b568e23ae3bebac15310397c037eaaeb 390 SMART SM00387 258 367 6.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01015 b568e23ae3bebac15310397c037eaaeb 390 SUPERFAMILY SSF47384 144 211 3.34E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CVS48_RS01015 b568e23ae3bebac15310397c037eaaeb 390 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 263 364 6.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01015 b568e23ae3bebac15310397c037eaaeb 390 Gene3D G3DSA:3.30.565.10 216 368 6.2E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01015 b568e23ae3bebac15310397c037eaaeb 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 364 2.8E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS01015 b568e23ae3bebac15310397c037eaaeb 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 309 2.8E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS01015 b568e23ae3bebac15310397c037eaaeb 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 345 2.8E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS01015 b568e23ae3bebac15310397c037eaaeb 390 Gene3D G3DSA:1.10.287.130 119 209 3.0E-4 T 29-03-2018 CVS48_RS01015 b568e23ae3bebac15310397c037eaaeb 390 SUPERFAMILY SSF55874 203 370 1.44E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS01485 6b6c7eb3d6f4450095791c43938919e2 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 268 3.2E-103 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CVS48_RS01485 6b6c7eb3d6f4450095791c43938919e2 271 SUPERFAMILY SSF52540 1 269 1.67E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS01485 6b6c7eb3d6f4450095791c43938919e2 271 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 226 2.9E-18 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CVS48_RS01485 6b6c7eb3d6f4450095791c43938919e2 271 Gene3D G3DSA:3.40.50.300 1 259 2.4E-52 T 29-03-2018 CVS48_RS01485 6b6c7eb3d6f4450095791c43938919e2 271 PIRSF PIRSF003092 1 271 4.4E-91 T 29-03-2018 IPR025501 ATP binding protein MinD CVS48_RS12500 3300d04d97ba1736a7a577f37bc4adfe 260 Gene3D G3DSA:3.40.190.10 25 140 3.1E-38 T 29-03-2018 CVS48_RS12500 3300d04d97ba1736a7a577f37bc4adfe 260 SUPERFAMILY SSF53850 7 256 3.96E-70 T 29-03-2018 CVS48_RS12500 3300d04d97ba1736a7a577f37bc4adfe 260 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CVS48_RS12500 3300d04d97ba1736a7a577f37bc4adfe 260 Gene3D G3DSA:3.40.190.10 141 251 5.6E-31 T 29-03-2018 CVS48_RS12500 3300d04d97ba1736a7a577f37bc4adfe 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 254 3.7E-65 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS12500 3300d04d97ba1736a7a577f37bc4adfe 260 SMART SM00062 35 256 2.6E-72 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS16380 25de2dbeb3af0cf58b548fb773ee9d31 175 SUPERFAMILY SSF88659 108 167 3.27E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16380 25de2dbeb3af0cf58b548fb773ee9d31 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 168 2.4E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16380 25de2dbeb3af0cf58b548fb773ee9d31 175 Pfam PF08281 Sigma-70, region 4 115 167 1.5E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16380 25de2dbeb3af0cf58b548fb773ee9d31 175 Gene3D G3DSA:1.10.1740.10 3 88 2.6E-16 T 29-03-2018 CVS48_RS16380 25de2dbeb3af0cf58b548fb773ee9d31 175 Gene3D G3DSA:1.10.10.10 92 171 3.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16380 25de2dbeb3af0cf58b548fb773ee9d31 175 SUPERFAMILY SSF88946 11 101 6.67E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS16380 25de2dbeb3af0cf58b548fb773ee9d31 175 Pfam PF04542 Sigma-70 region 2 15 83 1.3E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS09545 45ee48e2da7511ae92c322a162a46169 1043 Gene3D G3DSA:2.10.270.10 23 352 0.0021 T 29-03-2018 CVS48_RS09545 45ee48e2da7511ae92c322a162a46169 1043 Pfam PF14903 WG containing repeat 69 100 7.6E-7 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09545 45ee48e2da7511ae92c322a162a46169 1043 Pfam PF14903 WG containing repeat 954 980 4.7E-4 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09545 45ee48e2da7511ae92c322a162a46169 1043 Pfam PF14903 WG containing repeat 103 134 4.9E-8 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09545 45ee48e2da7511ae92c322a162a46169 1043 Pfam PF14903 WG containing repeat 574 602 6.9E-4 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09545 45ee48e2da7511ae92c322a162a46169 1043 Pfam PF14903 WG containing repeat 687 720 0.0032 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09545 45ee48e2da7511ae92c322a162a46169 1043 Pfam PF14903 WG containing repeat 662 687 0.068 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS09545 45ee48e2da7511ae92c322a162a46169 1043 SUPERFAMILY SSF69360 64 149 4.51E-6 T 29-03-2018 CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 Gene3D G3DSA:3.40.190.10 92 179 1.8E-19 T 29-03-2018 CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 Gene3D G3DSA:1.10.10.10 1 91 6.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 Gene3D G3DSA:3.40.190.10 180 262 1.2E-13 T 29-03-2018 CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.9E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 SUPERFAMILY SSF46785 1 80 7.62E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 Pfam PF03466 LysR substrate binding domain 89 289 9.2E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS16375 3ae3129ea77b4e74caf9dd6c6a2f8449 299 SUPERFAMILY SSF53850 90 291 4.59E-31 T 29-03-2018 CVS48_RS09495 8b78248181e06a7394c8425024d0a742 360 SUPERFAMILY SSF53850 53 358 9.21E-53 T 29-03-2018 CVS48_RS09495 8b78248181e06a7394c8425024d0a742 360 Gene3D G3DSA:3.40.190.10 156 312 5.1E-30 T 29-03-2018 CVS48_RS09495 8b78248181e06a7394c8425024d0a742 360 Gene3D G3DSA:3.40.190.10 14 155 5.6E-9 T 29-03-2018 CVS48_RS09495 8b78248181e06a7394c8425024d0a742 360 Pfam PF13416 Bacterial extracellular solute-binding protein 59 305 4.5E-39 T 29-03-2018 CVS48_RS16885 0d71eb6d3232b1b6e267cdaab771964b 261 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 184 261 7.8E-26 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CVS48_RS16885 0d71eb6d3232b1b6e267cdaab771964b 261 SUPERFAMILY SSF117143 93 223 6.02E-34 T 29-03-2018 CVS48_RS16885 0d71eb6d3232b1b6e267cdaab771964b 261 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 260 4.2E-109 T 29-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 CVS48_RS16885 0d71eb6d3232b1b6e267cdaab771964b 261 Pfam PF00460 Flagella basal body rod protein 5 35 3.6E-10 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CVS48_RS16885 0d71eb6d3232b1b6e267cdaab771964b 261 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CVS48_RS16885 0d71eb6d3232b1b6e267cdaab771964b 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 5.6E-42 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CVS48_RS16885 0d71eb6d3232b1b6e267cdaab771964b 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 146 244 8.6E-31 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CVS48_RS26365 1832993ffc695ec8991c355833b1cd46 317 SUPERFAMILY SSF53850 104 283 2.17E-13 T 29-03-2018 CVS48_RS26365 1832993ffc695ec8991c355833b1cd46 317 PIRSF PIRSF017082 1 316 1.9E-67 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS26365 1832993ffc695ec8991c355833b1cd46 317 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 40 313 7.8E-72 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS26365 1832993ffc695ec8991c355833b1cd46 317 Gene3D G3DSA:3.40.190.10 116 226 7.9E-9 T 29-03-2018 CVS48_RS03920 c62cfd17e1ffbf65be5dec013023a6e3 304 Gene3D G3DSA:1.10.3470.10 1 297 1.3E-48 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS03920 c62cfd17e1ffbf65be5dec013023a6e3 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 292 1.5E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS18565 d54efe6d7cfa23b24f61703cdc409450 151 Pfam PF00571 CBS domain 94 147 1.3E-14 T 29-03-2018 IPR000644 CBS domain CVS48_RS18565 d54efe6d7cfa23b24f61703cdc409450 151 Pfam PF00571 CBS domain 3 57 9.1E-13 T 29-03-2018 IPR000644 CBS domain CVS48_RS18565 d54efe6d7cfa23b24f61703cdc409450 151 Gene3D G3DSA:3.10.580.10 1 151 5.8E-33 T 29-03-2018 CVS48_RS18565 d54efe6d7cfa23b24f61703cdc409450 151 SUPERFAMILY SSF54631 1 147 1.89E-31 T 29-03-2018 CVS48_RS18565 d54efe6d7cfa23b24f61703cdc409450 151 SMART SM00116 100 147 1.7E-11 T 29-03-2018 IPR000644 CBS domain CVS48_RS18565 d54efe6d7cfa23b24f61703cdc409450 151 SMART SM00116 10 58 4.3E-7 T 29-03-2018 IPR000644 CBS domain CVS48_RS23630 61f90ba32572dcdd9c2b4fd1cea89c06 61 Pfam PF04964 Flp/Fap pilin component 8 52 2.6E-16 T 29-03-2018 IPR007047 Flp/Fap pilin component CVS48_RS13785 c04132c6ba18aef7a6391c3407f35b7a 317 Gene3D G3DSA:3.20.20.70 2 316 6.0E-109 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS13785 c04132c6ba18aef7a6391c3407f35b7a 317 TIGRFAM TIGR00874 talAB: transaldolase 3 314 1.0E-125 T 29-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CVS48_RS13785 c04132c6ba18aef7a6391c3407f35b7a 317 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 14 310 9.8E-93 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CVS48_RS13785 c04132c6ba18aef7a6391c3407f35b7a 317 SUPERFAMILY SSF51569 1 314 5.44E-103 T 29-03-2018 CVS48_RS13785 c04132c6ba18aef7a6391c3407f35b7a 317 ProSitePatterns PS00958 Transaldolase active site. 123 140 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CVS48_RS13785 c04132c6ba18aef7a6391c3407f35b7a 317 Hamap MF_00492 Transaldolase [tal]. 2 316 47.608 T 29-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CVS48_RS13785 c04132c6ba18aef7a6391c3407f35b7a 317 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CVS48_RS18735 c8d1414d42827ae01f638be8f2488d5f 328 SUPERFAMILY SSF49503 112 271 1.19E-41 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS18735 c8d1414d42827ae01f638be8f2488d5f 328 Gene3D G3DSA:2.60.40.420 102 251 1.1E-40 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS18735 c8d1414d42827ae01f638be8f2488d5f 328 SUPERFAMILY SSF46626 239 328 4.35E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18735 c8d1414d42827ae01f638be8f2488d5f 328 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 137 215 9.0E-16 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18735 c8d1414d42827ae01f638be8f2488d5f 328 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 161 209 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS18735 c8d1414d42827ae01f638be8f2488d5f 328 Pfam PF00034 Cytochrome c 241 328 4.5E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS18735 c8d1414d42827ae01f638be8f2488d5f 328 Gene3D G3DSA:1.10.760.10 252 328 5.0E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS04500 733a1273c30593c7f5abb1d36832af3f 380 Pfam PF13439 Glycosyltransferase Family 4 14 168 4.4E-22 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS04500 733a1273c30593c7f5abb1d36832af3f 380 Pfam PF00534 Glycosyl transferases group 1 203 347 6.8E-20 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS04500 733a1273c30593c7f5abb1d36832af3f 380 Gene3D G3DSA:3.40.50.2000 1 175 1.3E-22 T 29-03-2018 CVS48_RS04500 733a1273c30593c7f5abb1d36832af3f 380 Gene3D G3DSA:3.40.50.2000 176 349 3.8E-32 T 29-03-2018 CVS48_RS04500 733a1273c30593c7f5abb1d36832af3f 380 SUPERFAMILY SSF53756 2 366 4.32E-59 T 29-03-2018 CVS48_RS04195 6dd03fd6378bfeebc64afafd09255a3f 329 SUPERFAMILY SSF52402 31 250 5.45E-55 T 29-03-2018 CVS48_RS04195 6dd03fd6378bfeebc64afafd09255a3f 329 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 19 285 56.344 T 29-03-2018 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 CVS48_RS04195 6dd03fd6378bfeebc64afafd09255a3f 329 Pfam PF01171 PP-loop family 56 218 9.4E-15 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CVS48_RS04195 6dd03fd6378bfeebc64afafd09255a3f 329 Gene3D G3DSA:3.40.50.620 21 253 2.1E-40 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS17185 11b1d0222e3d6c9b17c03cc9d5dfa4df 398 SUPERFAMILY SSF53756 4 367 3.14E-24 T 29-03-2018 CVS48_RS17185 11b1d0222e3d6c9b17c03cc9d5dfa4df 398 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 2 395 33.268 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CVS48_RS17185 11b1d0222e3d6c9b17c03cc9d5dfa4df 398 Pfam PF02684 Lipid-A-disaccharide synthetase 6 386 5.1E-88 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CVS48_RS17185 11b1d0222e3d6c9b17c03cc9d5dfa4df 398 Gene3D G3DSA:3.40.50.2000 169 377 1.6E-12 T 29-03-2018 CVS48_RS17185 11b1d0222e3d6c9b17c03cc9d5dfa4df 398 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 4 392 8.9E-92 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CVS48_RS22300 8fb1ddb32a0d63e2bfda8e1283c673c6 370 SUPERFAMILY SSF51395 1 353 1.3E-115 T 29-03-2018 CVS48_RS22300 8fb1ddb32a0d63e2bfda8e1283c673c6 370 Gene3D G3DSA:3.20.20.70 1 363 1.1E-119 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS22300 8fb1ddb32a0d63e2bfda8e1283c673c6 370 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 338 4.3E-66 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CVS48_RS08560 7363c69bba284ee75b858335a2e139ef 495 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 69 492 4.6E-181 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CVS48_RS08560 7363c69bba284ee75b858335a2e139ef 495 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 21 493 2.1E-212 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CVS48_RS15175 837aed89c56a55255de45290f668da19 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.0E-39 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15175 837aed89c56a55255de45290f668da19 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.0E-39 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15175 837aed89c56a55255de45290f668da19 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.0E-39 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15175 837aed89c56a55255de45290f668da19 119 Gene3D G3DSA:1.10.1900.20 55 116 5.6E-29 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15175 837aed89c56a55255de45290f668da19 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 71 3.0E-22 T 29-03-2018 CVS48_RS15175 837aed89c56a55255de45290f668da19 119 SUPERFAMILY SSF74731 2 117 1.83E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15175 837aed89c56a55255de45290f668da19 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15175 837aed89c56a55255de45290f668da19 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.108 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15175 837aed89c56a55255de45290f668da19 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.8E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS15175 837aed89c56a55255de45290f668da19 119 Pfam PF00453 Ribosomal protein L20 3 109 9.4E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS14535 35ad031f07e82f6729de34f390fd91a1 290 Pfam PF03473 MOSC domain 158 285 6.2E-27 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CVS48_RS14535 35ad031f07e82f6729de34f390fd91a1 290 Pfam PF03476 MOSC N-terminal beta barrel domain 2 120 1.0E-31 T 29-03-2018 IPR005303 MOSC, N-terminal beta barrel CVS48_RS14535 35ad031f07e82f6729de34f390fd91a1 290 SUPERFAMILY SSF141673 7 133 5.36E-38 T 29-03-2018 CVS48_RS14535 35ad031f07e82f6729de34f390fd91a1 290 SUPERFAMILY SSF50800 167 288 2.3E-16 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CVS48_RS14535 35ad031f07e82f6729de34f390fd91a1 290 SUPERFAMILY SSF50800 1 51 2.3E-16 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CVS48_RS14535 35ad031f07e82f6729de34f390fd91a1 290 Gene3D G3DSA:2.40.33.20 1 289 7.2E-47 T 29-03-2018 CVS48_RS14665 f2ec1393e0720592c2cb99e8ab7e41a5 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 33 55 5.4E-7 T 29-03-2018 CVS48_RS14665 f2ec1393e0720592c2cb99e8ab7e41a5 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 383 398 5.4E-7 T 29-03-2018 CVS48_RS14665 f2ec1393e0720592c2cb99e8ab7e41a5 429 Gene3D G3DSA:3.50.50.60 20 422 4.6E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14665 f2ec1393e0720592c2cb99e8ab7e41a5 429 SUPERFAMILY SSF51905 32 257 1.94E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14665 f2ec1393e0720592c2cb99e8ab7e41a5 429 SUPERFAMILY SSF51905 349 414 1.94E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14665 f2ec1393e0720592c2cb99e8ab7e41a5 429 Pfam PF01266 FAD dependent oxidoreductase 33 385 8.1E-58 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 SUPERFAMILY SSF51905 307 368 1.17E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 SUPERFAMILY SSF51905 38 268 1.17E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 358 364 9.1E-25 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 388 400 9.1E-25 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 112 124 9.1E-25 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 50 9.1E-25 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 51 61 9.1E-25 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 67 79 9.1E-25 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 Pfam PF01266 FAD dependent oxidoreductase 39 370 3.7E-46 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 Gene3D G3DSA:3.50.50.60 8 434 2.6E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS22105 bf8e7ebdfaaec345fb2c41f592fd4445 559 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 420 532 1.3E-27 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CVS48_RS07020 2cdc0427678b3da50392be758396ee72 637 Gene3D G3DSA:3.40.50.2000 471 609 1.2E-8 T 29-03-2018 CVS48_RS07020 2cdc0427678b3da50392be758396ee72 637 SUPERFAMILY SSF53756 406 627 1.14E-12 T 29-03-2018 CVS48_RS27255 b0336961091a5affd7073f81cb00fd46 88 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS27255 b0336961091a5affd7073f81cb00fd46 88 Pfam PF01197 Ribosomal protein L31 1 78 5.6E-28 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS27255 b0336961091a5affd7073f81cb00fd46 88 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 78 5.0E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS27255 b0336961091a5affd7073f81cb00fd46 88 PRINTS PR01249 Ribosomal protein L31 signature 44 59 5.2E-14 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS27255 b0336961091a5affd7073f81cb00fd46 88 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.2E-14 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS27255 b0336961091a5affd7073f81cb00fd46 88 PRINTS PR01249 Ribosomal protein L31 signature 59 77 5.2E-14 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS27255 b0336961091a5affd7073f81cb00fd46 88 SUPERFAMILY SSF143800 1 78 5.1E-20 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS10135 27b2d8fc545ddf1420e6df2b08464caa 110 Gene3D G3DSA:2.10.260.10 8 52 1.5E-7 T 29-03-2018 CVS48_RS10135 27b2d8fc545ddf1420e6df2b08464caa 110 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 9 92 2.0E-27 T 29-03-2018 CVS48_RS10135 27b2d8fc545ddf1420e6df2b08464caa 110 SUPERFAMILY SSF89447 7 47 4.19E-7 T 29-03-2018 CVS48_RS10135 27b2d8fc545ddf1420e6df2b08464caa 110 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 8 107 9.6E-29 T 29-03-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 CVS48_RS10135 27b2d8fc545ddf1420e6df2b08464caa 110 SMART SM00966 9 55 0.0047 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CVS48_RS24100 8199e361eb49172f9a9967b721ef02cd 253 Gene3D G3DSA:3.30.450.40 82 252 2.0E-29 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS24100 8199e361eb49172f9a9967b721ef02cd 253 SMART SM00346 11 99 4.0E-5 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS24100 8199e361eb49172f9a9967b721ef02cd 253 Pfam PF09339 IclR helix-turn-helix domain 14 61 5.9E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS24100 8199e361eb49172f9a9967b721ef02cd 253 Gene3D G3DSA:1.10.10.10 1 73 5.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24100 8199e361eb49172f9a9967b721ef02cd 253 Pfam PF01614 Bacterial transcriptional regulator 133 243 5.1E-12 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS24100 8199e361eb49172f9a9967b721ef02cd 253 SUPERFAMILY SSF55781 82 249 1.77E-32 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS24100 8199e361eb49172f9a9967b721ef02cd 253 SUPERFAMILY SSF46785 13 72 5.65E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02725 c307094597eaaecc9b47e29e53a28c5b 269 SUPERFAMILY SSF53474 12 268 2.01E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS02725 c307094597eaaecc9b47e29e53a28c5b 269 Gene3D G3DSA:3.40.50.1820 9 269 1.3E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS02725 c307094597eaaecc9b47e29e53a28c5b 269 Pfam PF12697 Alpha/beta hydrolase family 30 260 1.7E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS03585 0b5eaad8c9f5fab189b15c369a014b3c 296 Pfam PF02616 Segregation and condensation protein ScpA 71 286 5.6E-34 T 29-03-2018 IPR003768 Segregation and condensation protein A CVS48_RS03585 0b5eaad8c9f5fab189b15c369a014b3c 296 Gene3D G3DSA:1.10.10.580 215 286 6.0E-13 T 29-03-2018 CVS48_RS03585 0b5eaad8c9f5fab189b15c369a014b3c 296 Hamap MF_01805 Segregation and condensation protein A [scpA]. 54 288 20.886 T 29-03-2018 IPR003768 Segregation and condensation protein A CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 SUPERFAMILY SSF51735 6 263 9.47E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 4.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 4.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 4.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 262 8.4E-65 T 29-03-2018 CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 Gene3D G3DSA:3.40.50.720 1 53 1.5E-6 T 29-03-2018 CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 Gene3D G3DSA:3.40.50.720 54 264 3.0E-62 T 29-03-2018 CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.1E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 1.1E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.1E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.1E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS21675 b1500840c0d6da1fc3f098165b0a7e42 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.1E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20620 d56f32bbcb70bf5e3f1efd024687a2a3 648 Gene3D G3DSA:2.30.38.10 392 480 1.2E-16 T 29-03-2018 CVS48_RS20620 d56f32bbcb70bf5e3f1efd024687a2a3 648 Pfam PF00501 AMP-binding enzyme 52 487 1.3E-76 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS20620 d56f32bbcb70bf5e3f1efd024687a2a3 648 Gene3D G3DSA:3.40.50.980 44 236 2.4E-28 T 29-03-2018 CVS48_RS20620 d56f32bbcb70bf5e3f1efd024687a2a3 648 Gene3D G3DSA:3.40.50.980 237 391 5.1E-38 T 29-03-2018 CVS48_RS20620 d56f32bbcb70bf5e3f1efd024687a2a3 648 SUPERFAMILY SSF56801 44 585 1.7E-119 T 29-03-2018 CVS48_RS20620 d56f32bbcb70bf5e3f1efd024687a2a3 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 497 572 2.6E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS20620 d56f32bbcb70bf5e3f1efd024687a2a3 648 Gene3D G3DSA:3.30.300.30 482 607 1.3E-23 T 29-03-2018 CVS48_RS20620 d56f32bbcb70bf5e3f1efd024687a2a3 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 231 242 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS01020 ccfdce6a0dbae87dfd6abf1d830a223a 228 SUPERFAMILY SSF52172 3 176 7.54E-32 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS01020 ccfdce6a0dbae87dfd6abf1d830a223a 228 Gene3D G3DSA:1.10.10.10 119 227 1.4E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS01020 ccfdce6a0dbae87dfd6abf1d830a223a 228 SMART SM00448 1 113 3.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS01020 ccfdce6a0dbae87dfd6abf1d830a223a 228 Pfam PF00072 Response regulator receiver domain 3 112 6.6E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS01020 ccfdce6a0dbae87dfd6abf1d830a223a 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 7.8E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS01020 ccfdce6a0dbae87dfd6abf1d830a223a 228 SMART SM00862 148 224 1.2E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS01020 ccfdce6a0dbae87dfd6abf1d830a223a 228 Gene3D G3DSA:3.40.50.2300 1 118 5.1E-31 T 29-03-2018 CVS48_RS27660 2ae8e2216186cef34217b5a305b39c6a 114 Pfam PF13473 Cupredoxin-like domain 10 110 1.4E-23 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain CVS48_RS27660 2ae8e2216186cef34217b5a305b39c6a 114 SUPERFAMILY SSF49503 12 111 3.39E-14 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS27660 2ae8e2216186cef34217b5a305b39c6a 114 Gene3D G3DSA:2.60.40.420 18 111 3.9E-5 T 29-03-2018 IPR008972 Cupredoxin CVS48_RS26150 5fd4229d7d18b597406b3cf573e059a7 374 Gene3D G3DSA:3.40.50.2000 175 351 3.7E-34 T 29-03-2018 CVS48_RS26150 5fd4229d7d18b597406b3cf573e059a7 374 Gene3D G3DSA:3.40.50.2000 6 174 1.2E-16 T 29-03-2018 CVS48_RS26150 5fd4229d7d18b597406b3cf573e059a7 374 Pfam PF13439 Glycosyltransferase Family 4 14 167 9.2E-20 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS26150 5fd4229d7d18b597406b3cf573e059a7 374 SUPERFAMILY SSF53756 3 370 1.48E-63 T 29-03-2018 CVS48_RS26150 5fd4229d7d18b597406b3cf573e059a7 374 Pfam PF00534 Glycosyl transferases group 1 192 345 1.4E-22 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS22330 ba3773f764650b9fac903943455981b8 141 SUPERFAMILY SSF82784 2 139 1.24E-39 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS22330 ba3773f764650b9fac903943455981b8 141 Pfam PF02566 OsmC-like protein 40 136 4.8E-20 T 29-03-2018 IPR003718 OsmC/Ohr family CVS48_RS22330 ba3773f764650b9fac903943455981b8 141 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 2 137 9.0E-61 T 29-03-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 CVS48_RS22330 ba3773f764650b9fac903943455981b8 141 Gene3D G3DSA:3.30.300.20 1 140 4.2E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS15750 073620b9fecda86bfca42efc7b1788fc 217 SUPERFAMILY SSF48695 12 189 9.99E-63 T 29-03-2018 IPR011031 Multihaem cytochrome CVS48_RS15750 073620b9fecda86bfca42efc7b1788fc 217 Gene3D G3DSA:1.10.468.10 58 207 7.4E-27 T 29-03-2018 CVS48_RS15750 073620b9fecda86bfca42efc7b1788fc 217 TIGRFAM TIGR02161 napC_nirT: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family 5 188 4.1E-99 T 29-03-2018 IPR011885 Periplasmic nitrate reductase c-type cytochrome, NapC/NirT GO:0016021|GO:0019333|GO:0020037 CVS48_RS15750 073620b9fecda86bfca42efc7b1788fc 217 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 15 188 1.2E-75 T 29-03-2018 IPR005126 NapC/NirT cytochrome c, N-terminal CVS48_RS15750 073620b9fecda86bfca42efc7b1788fc 217 PIRSF PIRSF000013 1 197 1.7E-104 T 29-03-2018 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 CVS48_RS08240 e6028d82570348a0b07b87dcea95da28 385 Gene3D G3DSA:2.40.160.10 23 385 2.1E-59 T 29-03-2018 CVS48_RS08240 e6028d82570348a0b07b87dcea95da28 385 Pfam PF13609 Gram-negative porin 8 365 7.9E-47 T 29-03-2018 CVS48_RS08240 e6028d82570348a0b07b87dcea95da28 385 SUPERFAMILY SSF56935 21 385 3.36E-64 T 29-03-2018 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 PIRSF PIRSF000349 1 204 1.2E-78 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 9.1E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 9.1E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 9.1E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 9.1E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 9.1E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 SUPERFAMILY SSF54719 93 203 1.31E-43 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 SUPERFAMILY SSF46609 1 91 3.8E-34 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 90 1.0E-30 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 198 2.0E-37 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CVS48_RS10570 8eca01aef1261641b43d9ee51765be5d 204 Gene3D G3DSA:1.10.287.990 20 90 9.0E-27 T 29-03-2018 CVS48_RS13530 444b5dfac4d73a3bcf48c1cb1c56a819 556 Gene3D G3DSA:3.90.226.10 264 507 1.1E-23 T 29-03-2018 CVS48_RS13530 444b5dfac4d73a3bcf48c1cb1c56a819 556 Gene3D G3DSA:3.90.226.10 508 556 0.047 T 29-03-2018 CVS48_RS13530 444b5dfac4d73a3bcf48c1cb1c56a819 556 Gene3D G3DSA:3.90.226.10 3 241 2.8E-37 T 29-03-2018 CVS48_RS13530 444b5dfac4d73a3bcf48c1cb1c56a819 556 SUPERFAMILY SSF52096 14 234 4.75E-30 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS13530 444b5dfac4d73a3bcf48c1cb1c56a819 556 SUPERFAMILY SSF52096 300 546 3.64E-12 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS13530 444b5dfac4d73a3bcf48c1cb1c56a819 556 TIGRFAM TIGR03222 benzo_boxC: benzoyl-CoA-dihydrodiol lyase 6 556 6.1E-296 T 29-03-2018 IPR017633 Benzoyl-CoA-dihydrodiol lyase MetaCyc: PWY-1361 CVS48_RS13530 444b5dfac4d73a3bcf48c1cb1c56a819 556 Pfam PF00378 Enoyl-CoA hydratase/isomerase 47 235 1.8E-22 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS16200 4a0294a5df933fbc93bf30b7ffedf57d 491 Gene3D G3DSA:3.40.309.10 271 466 4.9E-74 T 29-03-2018 CVS48_RS16200 4a0294a5df933fbc93bf30b7ffedf57d 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS16200 4a0294a5df933fbc93bf30b7ffedf57d 491 SUPERFAMILY SSF53720 10 484 1.7E-161 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS16200 4a0294a5df933fbc93bf30b7ffedf57d 491 Gene3D G3DSA:3.40.605.10 5 270 2.0E-86 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS16200 4a0294a5df933fbc93bf30b7ffedf57d 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CVS48_RS16200 4a0294a5df933fbc93bf30b7ffedf57d 491 Pfam PF00171 Aldehyde dehydrogenase family 18 479 3.4E-169 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS00380 df50c0333a2b8d64feb3df33f387b238 185 SUPERFAMILY SSF55729 22 178 5.23E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS00380 df50c0333a2b8d64feb3df33f387b238 185 Pfam PF13420 Acetyltransferase (GNAT) domain 24 168 4.0E-16 T 29-03-2018 CVS48_RS00380 df50c0333a2b8d64feb3df33f387b238 185 Gene3D G3DSA:3.40.630.30 15 183 2.6E-30 T 29-03-2018 CVS48_RS09955 8c63b603fa1ea6762d0b7ec11383c9ef 261 Pfam PF00290 Tryptophan synthase alpha chain 11 244 2.4E-68 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS09955 8c63b603fa1ea6762d0b7ec11383c9ef 261 SUPERFAMILY SSF51366 1 244 8.29E-69 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CVS48_RS09955 8c63b603fa1ea6762d0b7ec11383c9ef 261 Gene3D G3DSA:3.20.20.70 1 260 1.5E-55 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS09955 8c63b603fa1ea6762d0b7ec11383c9ef 261 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 10 257 5.3E-74 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS09955 8c63b603fa1ea6762d0b7ec11383c9ef 261 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 11 261 30.211 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CVS48_RS23605 f35fc7acbb48d57db47f87c513ef9c9a 461 Pfam PF13629 Pilus formation protein N terminal region 42 115 5.3E-16 T 29-03-2018 IPR032789 Pilus formation protein, N-terminal CVS48_RS23605 f35fc7acbb48d57db47f87c513ef9c9a 461 PRINTS PR00811 Bacterial general secretion pathway protein D signature 405 419 6.9E-15 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS23605 f35fc7acbb48d57db47f87c513ef9c9a 461 PRINTS PR00811 Bacterial general secretion pathway protein D signature 382 400 6.9E-15 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS23605 f35fc7acbb48d57db47f87c513ef9c9a 461 PRINTS PR00811 Bacterial general secretion pathway protein D signature 180 190 6.9E-15 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS23605 f35fc7acbb48d57db47f87c513ef9c9a 461 PRINTS PR00811 Bacterial general secretion pathway protein D signature 285 295 6.9E-15 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS23605 f35fc7acbb48d57db47f87c513ef9c9a 461 PRINTS PR00811 Bacterial general secretion pathway protein D signature 248 272 6.9E-15 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS23605 f35fc7acbb48d57db47f87c513ef9c9a 461 Pfam PF00263 Bacterial type II and III secretion system protein 252 418 4.9E-44 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 Pfam PF13180 PDZ domain 397 477 4.1E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 Pfam PF13180 PDZ domain 285 371 2.5E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 Pfam PF13365 Trypsin-like peptidase domain 112 245 6.5E-36 T 29-03-2018 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 56 475 3.2E-146 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 SUPERFAMILY SSF50494 109 293 7.87E-64 T 29-03-2018 IPR009003 Peptidase S1, PA clan CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 SUPERFAMILY SSF50494 41 75 7.87E-64 T 29-03-2018 IPR009003 Peptidase S1, PA clan CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 Gene3D G3DSA:2.40.10.10 178 278 2.3E-36 T 29-03-2018 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 Gene3D G3DSA:2.30.42.10 279 388 3.1E-26 T 29-03-2018 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 PRINTS PR00834 HtrA/DegQ protease family signature 121 133 1.3E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 PRINTS PR00834 HtrA/DegQ protease family signature 238 255 1.3E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 PRINTS PR00834 HtrA/DegQ protease family signature 324 336 1.3E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 PRINTS PR00834 HtrA/DegQ protease family signature 182 206 1.3E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 PRINTS PR00834 HtrA/DegQ protease family signature 142 162 1.3E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 PRINTS PR00834 HtrA/DegQ protease family signature 216 233 1.3E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 SUPERFAMILY SSF50156 265 374 2.7E-22 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 SUPERFAMILY SSF50156 394 478 1.09E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 Gene3D G3DSA:2.30.42.10 393 478 1.1E-16 T 29-03-2018 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 SMART SM00228 395 470 9.5E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 SMART SM00228 284 366 4.3E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS27220 cd7d6f1610bfda9d0daa6b38a48ed133 480 Gene3D G3DSA:2.40.10.10 52 177 2.7E-38 T 29-03-2018 CVS48_RS03970 39dcfff9d09f88456367603a8330b4bc 207 SUPERFAMILY SSF48498 96 206 3.56E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS03970 39dcfff9d09f88456367603a8330b4bc 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.1E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS03970 39dcfff9d09f88456367603a8330b4bc 207 Gene3D G3DSA:1.10.357.10 71 207 1.0E-23 T 29-03-2018 CVS48_RS03970 39dcfff9d09f88456367603a8330b4bc 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 8.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS03970 39dcfff9d09f88456367603a8330b4bc 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 8.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS03970 39dcfff9d09f88456367603a8330b4bc 207 Gene3D G3DSA:1.10.10.60 1 70 6.3E-20 T 29-03-2018 CVS48_RS03970 39dcfff9d09f88456367603a8330b4bc 207 SUPERFAMILY SSF46689 21 98 2.49E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS15600 ef0043c79746283c364263b410339870 273 Gene3D G3DSA:3.20.20.410 2 273 9.6E-79 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CVS48_RS15600 ef0043c79746283c364263b410339870 273 SUPERFAMILY SSF117396 13 273 2.75E-71 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CVS48_RS15600 ef0043c79746283c364263b410339870 273 Pfam PF01904 Protein of unknown function DUF72 31 271 5.9E-58 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CVS48_RS03215 e0920940318a90bfe57b3e134ff4bdeb 223 SUPERFAMILY SSF52172 1 162 6.26E-37 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS03215 e0920940318a90bfe57b3e134ff4bdeb 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 5.0E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS03215 e0920940318a90bfe57b3e134ff4bdeb 223 Gene3D G3DSA:3.40.50.2300 1 117 2.9E-32 T 29-03-2018 CVS48_RS03215 e0920940318a90bfe57b3e134ff4bdeb 223 SMART SM00862 145 217 3.1E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS03215 e0920940318a90bfe57b3e134ff4bdeb 223 Gene3D G3DSA:1.10.10.10 118 223 2.9E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03215 e0920940318a90bfe57b3e134ff4bdeb 223 SMART SM00448 1 112 2.5E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS03215 e0920940318a90bfe57b3e134ff4bdeb 223 Pfam PF00072 Response regulator receiver domain 3 112 9.2E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS14600 d2e4628035694a5e4b17107bed83557a 205 Gene3D G3DSA:3.30.1690.10 51 205 8.4E-19 T 29-03-2018 CVS48_RS14600 d2e4628035694a5e4b17107bed83557a 205 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 36 9.4E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS14600 d2e4628035694a5e4b17107bed83557a 205 Pfam PF07963 Prokaryotic N-terminal methylation motif 12 35 2.1E-4 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CVS48_RS14600 d2e4628035694a5e4b17107bed83557a 205 SUPERFAMILY SSF54523 45 205 9.94E-19 T 29-03-2018 CVS48_RS14600 d2e4628035694a5e4b17107bed83557a 205 Pfam PF08805 PilS N terminal 116 204 5.2E-10 T 29-03-2018 IPR014911 Type 4 secretion system, PilS, N-terminal CVS48_RS17915 e52adb636c8581a95fedf95425dbdaa3 116 Gene3D G3DSA:3.10.180.10 2 116 2.4E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS17915 e52adb636c8581a95fedf95425dbdaa3 116 SUPERFAMILY SSF54593 13 115 3.99E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS00930 5f6ae5c523287cd452f0d124f689705b 211 Gene3D G3DSA:1.20.1510.10 23 204 4.2E-16 T 29-03-2018 CVS48_RS00930 5f6ae5c523287cd452f0d124f689705b 211 Pfam PF01545 Cation efflux family 28 202 2.5E-12 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CVS48_RS00930 5f6ae5c523287cd452f0d124f689705b 211 SUPERFAMILY SSF161111 23 202 6.54E-30 T 29-03-2018 CVS48_RS27265 0a0d0c6860b657580d48e995bd89182f 466 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 413 8.2E-71 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS27265 0a0d0c6860b657580d48e995bd89182f 466 Pfam PF01554 MatE 24 184 9.5E-23 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS27265 0a0d0c6860b657580d48e995bd89182f 466 Pfam PF01554 MatE 249 410 8.3E-19 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS27265 0a0d0c6860b657580d48e995bd89182f 466 PIRSF PIRSF006603 10 464 9.5E-54 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CVS48_RS13340 9ba77a4688df68c91fbce1b6050b97da 180 Pfam PF03473 MOSC domain 58 166 8.8E-5 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CVS48_RS13340 9ba77a4688df68c91fbce1b6050b97da 180 SUPERFAMILY SSF50800 3 169 4.5E-37 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CVS48_RS13340 9ba77a4688df68c91fbce1b6050b97da 180 Gene3D G3DSA:2.40.33.20 1 180 3.5E-34 T 29-03-2018 CVS48_RS18680 1413cda02c1b898a1d96d15bb212a515 106 SUPERFAMILY SSF50022 1 103 6.15E-28 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS18680 1413cda02c1b898a1d96d15bb212a515 106 Pfam PF00355 Rieske [2Fe-2S] domain 3 90 2.1E-15 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS18680 1413cda02c1b898a1d96d15bb212a515 106 Gene3D G3DSA:2.102.10.10 1 106 2.0E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS23840 ab6ff89e5daed816150f067e0482c009 782 Pfam PF09317 Domain of unknown function (DUF1974) 475 763 1.8E-114 T 29-03-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 CVS48_RS23840 ab6ff89e5daed816150f067e0482c009 782 SUPERFAMILY SSF56645 81 316 2.88E-45 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS23840 ab6ff89e5daed816150f067e0482c009 782 Gene3D G3DSA:1.10.540.10 36 196 6.1E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS23840 ab6ff89e5daed816150f067e0482c009 782 Gene3D G3DSA:2.40.110.10 197 310 1.1E-14 T 29-03-2018 CVS48_RS23840 ab6ff89e5daed816150f067e0482c009 782 SUPERFAMILY SSF47203 321 468 1.48E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS23840 ab6ff89e5daed816150f067e0482c009 782 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 82 194 1.7E-20 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS23840 ab6ff89e5daed816150f067e0482c009 782 Gene3D G3DSA:1.20.140.10 311 470 7.1E-22 T 29-03-2018 CVS48_RS23840 ab6ff89e5daed816150f067e0482c009 782 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 321 468 1.6E-12 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS15350 a2f9e3b942cca8c77db80382e8e1fe82 237 Pfam PF00149 Calcineurin-like phosphoesterase 18 190 2.6E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS15350 a2f9e3b942cca8c77db80382e8e1fe82 237 Gene3D G3DSA:3.60.21.10 9 234 1.8E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS15350 a2f9e3b942cca8c77db80382e8e1fe82 237 SUPERFAMILY SSF56300 14 220 1.82E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS25400 076b4c67b5958de6d1831e9ffd236e18 448 Gene3D G3DSA:3.40.190.10 196 405 4.2E-39 T 29-03-2018 CVS48_RS25400 076b4c67b5958de6d1831e9ffd236e18 448 SUPERFAMILY SSF53850 91 316 3.13E-40 T 29-03-2018 CVS48_RS25400 076b4c67b5958de6d1831e9ffd236e18 448 Gene3D G3DSA:3.40.190.10 90 187 4.0E-12 T 29-03-2018 CVS48_RS25400 076b4c67b5958de6d1831e9ffd236e18 448 Pfam PF13379 NMT1-like family 90 328 5.6E-79 T 29-03-2018 CVS48_RS17325 b78d6000d32c69fa0f7bf39030dcc32a 222 Gene3D G3DSA:1.10.3720.10 2 219 5.8E-48 T 29-03-2018 CVS48_RS17325 b78d6000d32c69fa0f7bf39030dcc32a 222 SUPERFAMILY SSF161098 14 201 5.36E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS17325 b78d6000d32c69fa0f7bf39030dcc32a 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 216 7.3E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS17325 b78d6000d32c69fa0f7bf39030dcc32a 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 6.2E-30 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS10470 3db087dd31bbf9a242394d9d1a9b6e8d 270 Gene3D G3DSA:3.40.50.2300 1 137 5.2E-10 T 29-03-2018 CVS48_RS10470 3db087dd31bbf9a242394d9d1a9b6e8d 270 SUPERFAMILY SSF46894 152 236 1.59E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS10470 3db087dd31bbf9a242394d9d1a9b6e8d 270 Gene3D G3DSA:1.10.10.10 138 240 2.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10470 3db087dd31bbf9a242394d9d1a9b6e8d 270 SMART SM00862 157 234 2.0E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS10470 3db087dd31bbf9a242394d9d1a9b6e8d 270 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 234 9.6E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS10470 3db087dd31bbf9a242394d9d1a9b6e8d 270 SUPERFAMILY SSF52172 13 126 2.7E-10 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS03830 e3eaaf31cbbc769264fcec4e8a8b02b5 416 SUPERFAMILY SSF103473 12 403 3.14E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS03830 e3eaaf31cbbc769264fcec4e8a8b02b5 416 Gene3D G3DSA:1.20.1250.20 207 405 2.2E-16 T 29-03-2018 CVS48_RS03830 e3eaaf31cbbc769264fcec4e8a8b02b5 416 Gene3D G3DSA:1.20.1250.20 1 199 6.5E-19 T 29-03-2018 CVS48_RS03830 e3eaaf31cbbc769264fcec4e8a8b02b5 416 Pfam PF07690 Major Facilitator Superfamily 17 364 3.8E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS24350 3f203390840c547cfb79c3400def4f5e 242 Pfam PF05100 Phage minor tail protein L 26 240 1.2E-75 T 29-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail CVS48_RS24350 3f203390840c547cfb79c3400def4f5e 242 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 6 240 9.0E-89 T 29-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail CVS48_RS10770 2f2b9ed265b48c2ea7a7c21b57c5d218 292 SUPERFAMILY SSF63829 5 287 2.29E-58 T 29-03-2018 CVS48_RS10770 2f2b9ed265b48c2ea7a7c21b57c5d218 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 16 33 1.0E-25 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CVS48_RS10770 2f2b9ed265b48c2ea7a7c21b57c5d218 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 243 261 1.0E-25 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CVS48_RS10770 2f2b9ed265b48c2ea7a7c21b57c5d218 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 201 218 1.0E-25 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CVS48_RS10770 2f2b9ed265b48c2ea7a7c21b57c5d218 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 95 116 1.0E-25 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CVS48_RS10770 2f2b9ed265b48c2ea7a7c21b57c5d218 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 137 159 1.0E-25 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CVS48_RS10770 2f2b9ed265b48c2ea7a7c21b57c5d218 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 160 180 1.0E-25 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CVS48_RS10770 2f2b9ed265b48c2ea7a7c21b57c5d218 292 Gene3D G3DSA:2.120.10.30 14 290 1.9E-34 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS10770 2f2b9ed265b48c2ea7a7c21b57c5d218 292 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 261 1.8E-72 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CVS48_RS09125 e51c95b191631d6ed8da81ab10ed2933 329 SUPERFAMILY SSF53850 114 291 2.96E-15 T 29-03-2018 CVS48_RS09125 e51c95b191631d6ed8da81ab10ed2933 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 325 8.5E-100 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09125 e51c95b191631d6ed8da81ab10ed2933 329 PIRSF PIRSF017082 1 329 3.0E-89 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09125 e51c95b191631d6ed8da81ab10ed2933 329 Gene3D G3DSA:3.40.190.10 155 297 1.0E-11 T 29-03-2018 CVS48_RS27595 60ca66b654c2e78abefa63e4a16e3d99 237 Gene3D G3DSA:2.40.33.20 2 236 8.6E-57 T 29-03-2018 CVS48_RS27595 60ca66b654c2e78abefa63e4a16e3d99 237 Pfam PF03475 3-alpha domain 173 212 2.6E-10 T 29-03-2018 IPR005163 3-alpha domain CVS48_RS27595 60ca66b654c2e78abefa63e4a16e3d99 237 SUPERFAMILY SSF50800 4 228 7.85E-78 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CVS48_RS27595 60ca66b654c2e78abefa63e4a16e3d99 237 Pfam PF03473 MOSC domain 49 163 4.6E-28 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CVS48_RS26130 af4fb63edd366c9c37663d1cc992c376 254 Gene3D G3DSA:3.40.50.620 69 216 6.2E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS26130 af4fb63edd366c9c37663d1cc992c376 254 Pfam PF02698 DUF218 domain 79 244 3.2E-32 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CVS48_RS10740 6790fa6d8fa5dcfbee0afa260d328fc3 237 Pfam PF00072 Response regulator receiver domain 13 121 1.8E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS10740 6790fa6d8fa5dcfbee0afa260d328fc3 237 Gene3D G3DSA:1.10.10.10 131 236 7.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10740 6790fa6d8fa5dcfbee0afa260d328fc3 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 230 9.8E-16 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS10740 6790fa6d8fa5dcfbee0afa260d328fc3 237 SUPERFAMILY SSF52172 10 175 1.42E-34 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS10740 6790fa6d8fa5dcfbee0afa260d328fc3 237 SMART SM00448 11 123 7.7E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS10740 6790fa6d8fa5dcfbee0afa260d328fc3 237 SMART SM00862 157 230 4.6E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS10740 6790fa6d8fa5dcfbee0afa260d328fc3 237 Gene3D G3DSA:3.40.50.2300 4 130 9.0E-32 T 29-03-2018 CVS48_RS23800 864cf862e9030f1da59b32591065d59a 297 SUPERFAMILY SSF53448 5 125 7.22E-17 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS23800 864cf862e9030f1da59b32591065d59a 297 SUPERFAMILY SSF53448 152 204 7.22E-17 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS23800 864cf862e9030f1da59b32591065d59a 297 Pfam PF00535 Glycosyl transferase family 2 7 131 1.3E-11 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS23800 864cf862e9030f1da59b32591065d59a 297 Gene3D G3DSA:3.90.550.10 2 269 3.0E-18 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS20770 3e81ec30ba279a37252bfbef7f081a01 537 Pfam PF01593 Flavin containing amine oxidoreductase 215 266 2.6E-5 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CVS48_RS20770 3e81ec30ba279a37252bfbef7f081a01 537 PIRSF PIRSF038984 1 536 3.5E-245 T 29-03-2018 IPR028348 FAD dependent protein CVS48_RS20770 3e81ec30ba279a37252bfbef7f081a01 537 SUPERFAMILY SSF51905 100 286 1.85E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS20770 3e81ec30ba279a37252bfbef7f081a01 537 SUPERFAMILY SSF51905 479 529 1.85E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS20770 3e81ec30ba279a37252bfbef7f081a01 537 Gene3D G3DSA:3.50.50.60 85 534 6.9E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS21980 2e49737de2a7ed3ba374c7f7c1c2dc18 251 Pfam PF01435 Peptidase family M48 71 246 5.2E-26 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CVS48_RS21980 2e49737de2a7ed3ba374c7f7c1c2dc18 251 Gene3D G3DSA:3.30.2010.10 59 149 1.4E-18 T 29-03-2018 CVS48_RS06655 0dd98471ccf7eea59468060d5617b828 182 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 10 165 1.6E-54 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CVS48_RS06655 0dd98471ccf7eea59468060d5617b828 182 PIRSF PIRSF028301 5 178 1.3E-58 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CVS48_RS06655 0dd98471ccf7eea59468060d5617b828 182 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 14 164 4.3E-56 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CVS48_RS02870 a7cc32c54ec178b692655c625dfddd3c 230 SUPERFAMILY SSF158682 78 225 1.02E-22 T 29-03-2018 CVS48_RS02870 a7cc32c54ec178b692655c625dfddd3c 230 Gene3D G3DSA:1.10.3680.10 86 230 1.1E-13 T 29-03-2018 IPR029024 TerB-like CVS48_RS02870 a7cc32c54ec178b692655c625dfddd3c 230 Pfam PF04391 Protein of unknown function (DUF533) 43 224 2.8E-62 T 29-03-2018 IPR007486 Inner membrane protein YebE CVS48_RS05080 43a35d2ad7e8a050eee76d875d6da41a 270 PRINTS PR00164 ABC-2 type transport system membrane protein signature 190 209 6.2E-10 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS05080 43a35d2ad7e8a050eee76d875d6da41a 270 PRINTS PR00164 ABC-2 type transport system membrane protein signature 72 94 6.2E-10 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS05080 43a35d2ad7e8a050eee76d875d6da41a 270 PRINTS PR00164 ABC-2 type transport system membrane protein signature 210 229 6.2E-10 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS05080 43a35d2ad7e8a050eee76d875d6da41a 270 PIRSF PIRSF006648 1 267 1.9E-24 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CVS48_RS05080 43a35d2ad7e8a050eee76d875d6da41a 270 Pfam PF01061 ABC-2 type transporter 25 233 2.0E-32 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CVS48_RS22215 e9582adc18cae46a253dc10189f15530 101 Gene3D G3DSA:1.20.59.10 2 100 1.8E-24 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS22215 e9582adc18cae46a253dc10189f15530 101 Pfam PF01817 Chorismate mutase type II 15 89 1.7E-16 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS22215 e9582adc18cae46a253dc10189f15530 101 SMART SM00830 15 95 1.8E-21 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS22215 e9582adc18cae46a253dc10189f15530 101 SUPERFAMILY SSF48600 6 93 3.51E-21 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CVS48_RS25960 c88052279463247754a81cce497f985f 252 Gene3D G3DSA:3.40.50.300 4 252 9.2E-53 T 29-03-2018 CVS48_RS25960 c88052279463247754a81cce497f985f 252 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 248 1.4E-7 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS25960 c88052279463247754a81cce497f985f 252 SUPERFAMILY SSF52540 7 247 1.38E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS25960 c88052279463247754a81cce497f985f 252 SMART SM00382 32 226 1.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS25960 c88052279463247754a81cce497f985f 252 Pfam PF00005 ABC transporter 24 177 8.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05260 3e63fea272b05f30fd602c10565cec58 192 Gene3D G3DSA:3.30.450.40 9 190 3.3E-8 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS05260 3e63fea272b05f30fd602c10565cec58 192 SUPERFAMILY SSF55781 76 172 1.33E-7 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS15925 a0112f610f5b8130ff5d3c9a61c24217 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 251 2.5E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS15925 a0112f610f5b8130ff5d3c9a61c24217 256 SUPERFAMILY SSF161098 58 243 6.8E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS15925 a0112f610f5b8130ff5d3c9a61c24217 256 Gene3D G3DSA:1.10.3720.10 11 256 8.9E-26 T 29-03-2018 CVS48_RS26930 eec27da8d776cbeb6454eff58cc6568c 479 Gene3D G3DSA:1.10.10.10 1 70 5.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26930 eec27da8d776cbeb6454eff58cc6568c 479 SUPERFAMILY SSF53383 116 475 3.09E-91 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS26930 eec27da8d776cbeb6454eff58cc6568c 479 SMART SM00345 10 69 2.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS26930 eec27da8d776cbeb6454eff58cc6568c 479 Pfam PF00155 Aminotransferase class I and II 142 466 4.0E-30 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS26930 eec27da8d776cbeb6454eff58cc6568c 479 SUPERFAMILY SSF46785 2 79 2.45E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS26930 eec27da8d776cbeb6454eff58cc6568c 479 Gene3D G3DSA:3.90.1150.10 381 478 1.5E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS26930 eec27da8d776cbeb6454eff58cc6568c 479 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 4.1E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS26930 eec27da8d776cbeb6454eff58cc6568c 479 Gene3D G3DSA:3.40.640.10 128 380 1.4E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS02915 beed4c1f4a912f7fa3e7f640c7e83411 239 Pfam PF06551 Protein of unknown function (DUF1120) 33 132 8.2E-9 T 29-03-2018 IPR010546 Protein of unknown function DUF1120 CVS48_RS02915 beed4c1f4a912f7fa3e7f640c7e83411 239 Gene3D G3DSA:2.60.40.1090 31 239 4.4E-6 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CVS48_RS21345 3368c6aa786efb99e872c5c22d3ecd0a 326 SUPERFAMILY SSF53850 115 288 1.55E-13 T 29-03-2018 CVS48_RS21345 3368c6aa786efb99e872c5c22d3ecd0a 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 1.2E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21345 3368c6aa786efb99e872c5c22d3ecd0a 326 Gene3D G3DSA:3.40.190.10 137 296 1.4E-9 T 29-03-2018 CVS48_RS21345 3368c6aa786efb99e872c5c22d3ecd0a 326 PIRSF PIRSF017082 2 326 7.0E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25240 3dcd8f64b6c910bc523b65308eab2453 311 Gene3D G3DSA:3.20.20.70 1 304 1.1E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS25240 3dcd8f64b6c910bc523b65308eab2453 311 Pfam PF00682 HMGL-like 5 284 1.3E-37 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CVS48_RS25240 3dcd8f64b6c910bc523b65308eab2453 311 SUPERFAMILY SSF51569 1 301 8.61E-60 T 29-03-2018 CVS48_RS26050 e0f8d5486d6b78eb5b0250b7adeacfec 133 SUPERFAMILY SSF54427 34 131 5.94E-34 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS26050 e0f8d5486d6b78eb5b0250b7adeacfec 133 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 8 131 27.268 T 29-03-2018 IPR023006 Uncharacterised protein family UPF0225 CVS48_RS26050 e0f8d5486d6b78eb5b0250b7adeacfec 133 Gene3D G3DSA:3.10.450.50 10 133 2.3E-43 T 29-03-2018 CVS48_RS23435 2ff5e740366c4b0debd2f7ebb7494804 261 Gene3D G3DSA:1.10.12.10 216 257 2.0E-10 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS23435 2ff5e740366c4b0debd2f7ebb7494804 261 SUPERFAMILY SSF52096 1 259 1.23E-78 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS23435 2ff5e740366c4b0debd2f7ebb7494804 261 Gene3D G3DSA:3.90.226.10 1 215 3.1E-64 T 29-03-2018 CVS48_RS23435 2ff5e740366c4b0debd2f7ebb7494804 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 255 1.9E-57 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS21610 4d24674a55dc102ac6008cef9a9bd5b2 383 Gene3D G3DSA:3.90.1520.10 1 86 0.0012 T 29-03-2018 CVS48_RS21610 4d24674a55dc102ac6008cef9a9bd5b2 383 Pfam PF15978 Tn7-like transposition protein D 203 282 2.9E-9 T 29-03-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl CVS48_RS21610 4d24674a55dc102ac6008cef9a9bd5b2 383 Pfam PF06527 TniQ 4 150 4.2E-16 T 29-03-2018 IPR009492 TniQ CVS48_RS21455 a2f91c57baf1b4c1a79c52ff96ebe421 572 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 210 528 6.5E-86 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal CVS48_RS21455 a2f91c57baf1b4c1a79c52ff96ebe421 572 Gene3D G3DSA:3.10.20.310 87 152 1.4E-7 T 29-03-2018 CVS48_RS21455 a2f91c57baf1b4c1a79c52ff96ebe421 572 Pfam PF08479 POTRA domain, ShlB-type 91 152 4.1E-10 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type CVS48_RS21455 a2f91c57baf1b4c1a79c52ff96ebe421 572 Pfam PF17287 POTRA domain 153 205 1.3E-12 T 29-03-2018 IPR035251 ShlB, POTRA domain CVS48_RS21455 a2f91c57baf1b4c1a79c52ff96ebe421 572 PIRSF PIRSF029745 2 572 3.2E-111 T 29-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 CVS48_RS21455 a2f91c57baf1b4c1a79c52ff96ebe421 572 Gene3D G3DSA:2.40.160.50 177 572 5.2E-39 T 29-03-2018 CVS48_RS14980 636dcfaab7a46bec2005e4ea2d28c225 657 Gene3D G3DSA:3.10.350.10 162 221 2.1E-9 T 29-03-2018 CVS48_RS14980 636dcfaab7a46bec2005e4ea2d28c225 657 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 172 243 7.8E-23 T 29-03-2018 IPR020012 Motility protein FimV, N-terminal CVS48_RS14980 636dcfaab7a46bec2005e4ea2d28c225 657 Pfam PF01476 LysM domain 168 220 5.1E-5 T 29-03-2018 IPR018392 LysM domain CVS48_RS21205 0c2086e8c64e1228d271484091124c25 433 Gene3D G3DSA:3.65.10.10 224 432 6.2E-29 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS21205 0c2086e8c64e1228d271484091124c25 433 SUPERFAMILY SSF55205 1 430 6.38E-91 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CVS48_RS21205 0c2086e8c64e1228d271484091124c25 433 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 420 7.2E-53 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS21205 0c2086e8c64e1228d271484091124c25 433 Gene3D G3DSA:3.65.10.10 21 223 8.2E-37 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CVS48_RS25505 f0c1875273461d6c8934e3a72aebc175 184 Gene3D G3DSA:2.60.120.10 70 184 1.0E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS25505 f0c1875273461d6c8934e3a72aebc175 184 Pfam PF07883 Cupin domain 127 181 1.6E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS25505 f0c1875273461d6c8934e3a72aebc175 184 SUPERFAMILY SSF51182 75 181 1.84E-23 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS25505 f0c1875273461d6c8934e3a72aebc175 184 Gene3D G3DSA:1.10.260.40 2 69 3.7E-18 T 29-03-2018 CVS48_RS25505 f0c1875273461d6c8934e3a72aebc175 184 SUPERFAMILY SSF47413 2 67 7.6E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS25505 f0c1875273461d6c8934e3a72aebc175 184 SMART SM00530 7 62 4.6E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS25505 f0c1875273461d6c8934e3a72aebc175 184 Pfam PF01381 Helix-turn-helix 8 60 1.6E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS23640 e3f42b237600adc5d6dea93d8fa5dc53 569 Pfam PF08479 POTRA domain, ShlB-type 77 147 3.4E-17 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type CVS48_RS23640 e3f42b237600adc5d6dea93d8fa5dc53 569 Gene3D G3DSA:3.10.20.310 76 147 2.1E-13 T 29-03-2018 CVS48_RS23640 e3f42b237600adc5d6dea93d8fa5dc53 569 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 238 529 2.5E-19 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal CVS48_RS23640 e3f42b237600adc5d6dea93d8fa5dc53 569 Gene3D G3DSA:2.40.160.50 177 563 4.6E-36 T 29-03-2018 CVS48_RS11370 7c354cce2615823ba5ee738315947825 321 PIRSF PIRSF017082 3 321 2.0E-70 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11370 7c354cce2615823ba5ee738315947825 321 SUPERFAMILY SSF53850 108 281 5.72E-14 T 29-03-2018 CVS48_RS11370 7c354cce2615823ba5ee738315947825 321 Gene3D G3DSA:3.40.190.10 122 231 4.5E-9 T 29-03-2018 CVS48_RS11370 7c354cce2615823ba5ee738315947825 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 314 7.8E-83 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09220 195a6510d4ed81669afcfa1a1b0fc6f9 446 Pfam PF02667 Short chain fatty acid transporter 2 437 1.0E-128 T 29-03-2018 IPR006160 Short chain fatty acid transporter AtoE CVS48_RS24520 991e8c552b630be24c8681582c746f14 119 Gene3D G3DSA:4.10.430.10 75 113 5.9E-15 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CVS48_RS24520 991e8c552b630be24c8681582c746f14 119 SUPERFAMILY SSF81273 72 113 3.33E-10 T 29-03-2018 CVS48_RS24520 991e8c552b630be24c8681582c746f14 119 SMART SM00528 69 113 6.4E-10 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CVS48_RS24520 991e8c552b630be24c8681582c746f14 119 Pfam PF00816 H-NS histone family 10 105 4.9E-19 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 CVS48_RS22805 efb96e93127625039c8c02a74c106f2b 495 Gene3D G3DSA:3.90.1150.10 317 463 9.8E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS22805 efb96e93127625039c8c02a74c106f2b 495 Gene3D G3DSA:3.40.640.10 64 316 1.3E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS22805 efb96e93127625039c8c02a74c106f2b 495 SUPERFAMILY SSF53383 45 464 1.24E-74 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS22805 efb96e93127625039c8c02a74c106f2b 495 Pfam PF00266 Aminotransferase class-V 53 413 1.5E-46 T 29-03-2018 IPR000192 Aminotransferase class V domain CVS48_RS17255 359e4738a8df8fd4017716ba8d82f650 115 SUPERFAMILY SSF54285 10 84 1.29E-20 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CVS48_RS17255 359e4738a8df8fd4017716ba8d82f650 115 Gene3D G3DSA:3.10.20.280 6 94 7.1E-30 T 29-03-2018 IPR005346 RnfH protein CVS48_RS17255 359e4738a8df8fd4017716ba8d82f650 115 Hamap MF_00460 Protein RnfH [rnfH]. 11 101 22.121 T 29-03-2018 IPR005346 RnfH protein CVS48_RS17255 359e4738a8df8fd4017716ba8d82f650 115 Pfam PF03658 RnfH family Ubiquitin 11 93 2.6E-28 T 29-03-2018 IPR005346 RnfH protein CVS48_RS20495 cc5e8048fbbd21616803aff6d26c5aa8 277 SUPERFAMILY SSF48371 85 275 9.87E-37 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CVS48_RS20495 cc5e8048fbbd21616803aff6d26c5aa8 277 Gene3D G3DSA:1.25.40.70 58 162 0.2 T 29-03-2018 CVS48_RS20495 cc5e8048fbbd21616803aff6d26c5aa8 277 Gene3D G3DSA:1.25.40.290 168 277 3.0E-19 T 29-03-2018 CVS48_RS20495 cc5e8048fbbd21616803aff6d26c5aa8 277 Pfam PF13646 HEAT repeats 109 191 1.2E-7 T 29-03-2018 CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 Pfam PF14698 Argininosuccinate lyase C-terminal 380 456 4.2E-12 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 Pfam PF00206 Lyase 111 303 4.5E-25 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 PRINTS PR00149 Fumarate lyase superfamily signature 289 305 1.3E-6 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 PRINTS PR00149 Fumarate lyase superfamily signature 157 175 1.3E-6 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 PRINTS PR00149 Fumarate lyase superfamily signature 243 270 1.3E-6 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 PRINTS PR00149 Fumarate lyase superfamily signature 112 130 1.3E-6 T 29-03-2018 IPR000362 Fumarate lyase family CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 PRINTS PR00145 Argininosuccinate lyase family signature 203 219 8.6E-15 T 29-03-2018 CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 PRINTS PR00145 Argininosuccinate lyase family signature 152 172 8.6E-15 T 29-03-2018 CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 PRINTS PR00145 Argininosuccinate lyase family signature 111 133 8.6E-15 T 29-03-2018 CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 PRINTS PR00145 Argininosuccinate lyase family signature 289 305 8.6E-15 T 29-03-2018 CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 Gene3D G3DSA:1.10.40.30 387 458 2.1E-14 T 29-03-2018 CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 SUPERFAMILY SSF48557 38 481 5.81E-72 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CVS48_RS10050 6f94fb159d5a03d0668bdd698ed2dce0 515 Gene3D G3DSA:1.20.200.10 117 386 7.3E-50 T 29-03-2018 CVS48_RS09600 00639de691363f58f2f5e0808f54b1c8 711 Gene3D G3DSA:3.40.50.300 15 298 8.0E-25 T 29-03-2018 CVS48_RS09600 00639de691363f58f2f5e0808f54b1c8 711 Pfam PF13361 UvrD-like helicase C-terminal domain 568 628 7.7E-10 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CVS48_RS09600 00639de691363f58f2f5e0808f54b1c8 711 SUPERFAMILY SSF52540 465 631 6.7E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09600 00639de691363f58f2f5e0808f54b1c8 711 SUPERFAMILY SSF52540 17 436 6.7E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09600 00639de691363f58f2f5e0808f54b1c8 711 Gene3D G3DSA:3.40.50.300 299 653 1.8E-24 T 29-03-2018 CVS48_RS09600 00639de691363f58f2f5e0808f54b1c8 711 Pfam PF13245 AAA domain 22 280 3.5E-17 T 29-03-2018 CVS48_RS01750 979716f8ee53b0e92ca6c7d05c218a98 567 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 185 283 1.7E-16 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS01750 979716f8ee53b0e92ca6c7d05c218a98 567 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 408 427 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS01750 979716f8ee53b0e92ca6c7d05c218a98 567 Gene3D G3DSA:2.40.110.10 184 291 5.5E-28 T 29-03-2018 CVS48_RS01750 979716f8ee53b0e92ca6c7d05c218a98 567 Gene3D G3DSA:1.20.140.10 292 464 7.0E-37 T 29-03-2018 CVS48_RS01750 979716f8ee53b0e92ca6c7d05c218a98 567 SUPERFAMILY SSF47203 292 451 1.93E-40 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS01750 979716f8ee53b0e92ca6c7d05c218a98 567 SUPERFAMILY SSF56645 92 303 4.97E-42 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS01750 979716f8ee53b0e92ca6c7d05c218a98 567 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 294 449 1.3E-33 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Gene3D G3DSA:1.10.860.10 542 678 8.8E-17 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Pfam PF08275 DNA primase catalytic core, N-terminal domain 129 248 1.3E-35 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 SMART SM00493 256 327 4.3E-19 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 SUPERFAMILY SSF117023 548 668 6.54E-13 T 29-03-2018 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Gene3D G3DSA:3.90.580.10 1 100 7.8E-34 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Pfam PF13662 Toprim domain 257 322 7.6E-16 T 29-03-2018 IPR006171 TOPRIM domain CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Gene3D G3DSA:3.90.980.10 110 237 7.2E-39 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Pfam PF10410 DnaB-helicase binding domain of primase 366 421 2.3E-9 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 SMART SM00400 33 87 3.2E-34 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Hamap MF_00974 DNA primase [dnaG]. 1 674 27.061 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 SMART SM00766 550 674 3.1E-23 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Pfam PF08278 DNA primase DnaG DnaB-binding 552 673 2.2E-13 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 SUPERFAMILY SSF56731 119 419 2.88E-100 T 29-03-2018 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Gene3D G3DSA:1.20.50.20 367 418 1.6E-16 T 29-03-2018 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Gene3D G3DSA:3.40.1360.20 252 366 4.6E-31 T 29-03-2018 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 SUPERFAMILY SSF57783 2 97 4.25E-36 T 29-03-2018 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 Pfam PF01807 CHC2 zinc finger 3 97 3.2E-37 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CVS48_RS14765 e94f292b785191ed8f1ff218848e9d50 686 TIGRFAM TIGR01391 dnaG: DNA primase 2 414 9.8E-137 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CVS48_RS04950 a546c5a3bb9a6965b9a85bf5dad2f017 66 Pfam PF11137 Protein of unknown function (DUF2909) 1 60 1.5E-24 T 29-03-2018 IPR021313 Protein of unknown function DUF2909 CVS48_RS14100 8bbcb583c9e1eb73b8bc159973a5d007 232 Pfam PF10099 Anti-sigma-K factor rskA 62 229 3.9E-29 T 29-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 CVS48_RS04350 b061d79e93381cc772ad8ccb7bf8800b 245 SUPERFAMILY SSF88713 7 233 3.34E-43 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CVS48_RS04350 b061d79e93381cc772ad8ccb7bf8800b 245 Pfam PF01522 Polysaccharide deacetylase 8 158 8.3E-22 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CVS48_RS04350 b061d79e93381cc772ad8ccb7bf8800b 245 Gene3D G3DSA:3.20.20.370 8 240 5.0E-39 T 29-03-2018 CVS48_RS26315 39521167c6f79bca565a3f2deffcd3e9 330 SUPERFAMILY SSF161098 92 305 2.35E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS26315 39521167c6f79bca565a3f2deffcd3e9 330 Gene3D G3DSA:1.10.3720.10 3 308 7.4E-41 T 29-03-2018 CVS48_RS26315 39521167c6f79bca565a3f2deffcd3e9 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 7.8E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS11145 ef99b0195f1e0db762d668ab16661b13 193 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 6 154 5.0E-45 T 29-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CVS48_RS11145 ef99b0195f1e0db762d668ab16661b13 193 Gene3D G3DSA:2.60.120.10 9 174 6.0E-46 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS11145 ef99b0195f1e0db762d668ab16661b13 193 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 4 172 33.443 T 29-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CVS48_RS11145 ef99b0195f1e0db762d668ab16661b13 193 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 8 167 8.0E-79 T 29-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CVS48_RS11145 ef99b0195f1e0db762d668ab16661b13 193 SUPERFAMILY SSF51182 5 173 6.68E-52 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS27940 2bd1b9079dc777045a7417916fc0b003 140 PIRSF PIRSF004638 1 140 1.4E-51 T 29-03-2018 IPR005265 Uncharacterised protein family UPF0093 CVS48_RS27940 2bd1b9079dc777045a7417916fc0b003 140 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 140 2.1E-47 T 29-03-2018 IPR005265 Uncharacterised protein family UPF0093 CVS48_RS12570 6467fb0f55a7627c981db73d5754222e 277 Pfam PF01497 Periplasmic binding protein 25 249 2.4E-40 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CVS48_RS12570 6467fb0f55a7627c981db73d5754222e 277 SUPERFAMILY SSF53807 20 267 3.26E-51 T 29-03-2018 CVS48_RS12570 6467fb0f55a7627c981db73d5754222e 277 Gene3D G3DSA:3.40.50.1980 128 276 5.3E-25 T 29-03-2018 CVS48_RS12570 6467fb0f55a7627c981db73d5754222e 277 Gene3D G3DSA:3.40.50.1980 21 127 4.2E-26 T 29-03-2018 CVS48_RS03985 e69c66db67d56419ad25c7af73153026 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 116 136 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS03985 e69c66db67d56419ad25c7af73153026 277 Gene3D G3DSA:1.10.12.10 233 275 6.2E-9 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS03985 e69c66db67d56419ad25c7af73153026 277 Gene3D G3DSA:3.90.226.10 16 232 9.4E-45 T 29-03-2018 CVS48_RS03985 e69c66db67d56419ad25c7af73153026 277 SUPERFAMILY SSF52096 35 271 2.23E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS03985 e69c66db67d56419ad25c7af73153026 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 36 272 4.5E-41 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS21135 2d3b938bcfb7c9f4eec9cc6287c3ce05 190 Gene3D G3DSA:3.40.50.850 2 190 8.6E-29 T 29-03-2018 CVS48_RS21135 2d3b938bcfb7c9f4eec9cc6287c3ce05 190 SUPERFAMILY SSF52499 5 189 1.06E-36 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS21135 2d3b938bcfb7c9f4eec9cc6287c3ce05 190 Pfam PF00857 Isochorismatase family 12 183 4.1E-21 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS18785 34c2697e8a4c6b7f3427d095634e5542 335 SUPERFAMILY SSF56281 10 319 2.17E-56 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS18785 34c2697e8a4c6b7f3427d095634e5542 335 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 5 334 2.0E-139 T 29-03-2018 IPR026360 Putative exonuclease, DNA ligase-associated CVS48_RS18785 34c2697e8a4c6b7f3427d095634e5542 335 Gene3D G3DSA:3.60.15.10 16 199 1.2E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS03355 9360b1a751d4ba13d8bcbc41ae2caa66 251 SUPERFAMILY SSF53955 115 250 4.13E-43 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS03355 9360b1a751d4ba13d8bcbc41ae2caa66 251 Gene3D G3DSA:1.10.530.10 63 251 4.3E-44 T 29-03-2018 CVS48_RS03355 9360b1a751d4ba13d8bcbc41ae2caa66 251 Pfam PF01464 Transglycosylase SLT domain 124 227 1.3E-27 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CVS48_RS18370 6b6d4d9e439f1477b53d136dbadd50aa 728 Pfam PF02446 4-alpha-glucanotransferase 573 703 4.0E-17 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CVS48_RS18370 6b6d4d9e439f1477b53d136dbadd50aa 728 Pfam PF02446 4-alpha-glucanotransferase 174 544 2.3E-73 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CVS48_RS18370 6b6d4d9e439f1477b53d136dbadd50aa 728 Gene3D G3DSA:3.20.20.80 152 726 1.6E-138 T 29-03-2018 CVS48_RS18370 6b6d4d9e439f1477b53d136dbadd50aa 728 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 135 546 9.2E-72 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CVS48_RS18370 6b6d4d9e439f1477b53d136dbadd50aa 728 SUPERFAMILY SSF51445 574 604 5.83E-119 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18370 6b6d4d9e439f1477b53d136dbadd50aa 728 SUPERFAMILY SSF51445 139 547 5.83E-119 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS18370 6b6d4d9e439f1477b53d136dbadd50aa 728 SUPERFAMILY SSF51445 637 719 5.83E-119 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CVS48_RS15455 f56932c21b8c58b41810f6f0ab011d54 248 Pfam PF00535 Glycosyl transferase family 2 5 127 1.9E-16 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS15455 f56932c21b8c58b41810f6f0ab011d54 248 SUPERFAMILY SSF53448 3 230 7.59E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS15455 f56932c21b8c58b41810f6f0ab011d54 248 Gene3D G3DSA:3.90.550.10 1 247 2.5E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS11005 2fd2abb476eaf146a394c385e3160fc9 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS11005 2fd2abb476eaf146a394c385e3160fc9 256 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 5 250 1.1E-90 T 29-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 CVS48_RS11005 2fd2abb476eaf146a394c385e3160fc9 256 SMART SM00382 30 230 9.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS11005 2fd2abb476eaf146a394c385e3160fc9 256 SUPERFAMILY SSF52540 5 240 1.21E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS11005 2fd2abb476eaf146a394c385e3160fc9 256 Pfam PF00005 ABC transporter 21 181 1.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS11005 2fd2abb476eaf146a394c385e3160fc9 256 Gene3D G3DSA:3.40.50.300 1 245 2.8E-60 T 29-03-2018 CVS48_RS08435 00a0edf15190e686485c61e5addeb28a 877 Gene3D G3DSA:3.40.50.300 471 845 4.4E-9 T 29-03-2018 CVS48_RS08435 00a0edf15190e686485c61e5addeb28a 877 SUPERFAMILY SSF52540 450 818 4.97E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS28560 272ed3247e571bdc1315381c8c8ce38a 358 SMART SM00771 214 336 2.2E-24 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 CVS48_RS28560 272ed3247e571bdc1315381c8c8ce38a 358 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 280 326 5.1E-7 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 CVS48_RS28560 272ed3247e571bdc1315381c8c8ce38a 358 Gene3D G3DSA:3.30.1400.10 215 337 2.2E-15 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 CVS48_RS28560 272ed3247e571bdc1315381c8c8ce38a 358 SUPERFAMILY SSF64383 228 340 1.44E-11 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 CVS48_RS06375 5badee45889eb21232d81f920d1a96fc 263 Pfam PF00005 ABC transporter 38 176 2.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS06375 5badee45889eb21232d81f920d1a96fc 263 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS06375 5badee45889eb21232d81f920d1a96fc 263 SUPERFAMILY SSF52540 19 243 1.62E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06375 5badee45889eb21232d81f920d1a96fc 263 SMART SM00382 47 227 2.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS06375 5badee45889eb21232d81f920d1a96fc 263 Gene3D G3DSA:3.40.50.300 16 237 3.1E-55 T 29-03-2018 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 SUPERFAMILY SSF56235 8 542 1.72E-177 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 136 155 4.6E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 234 250 4.6E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 436 453 4.6E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 118 136 4.6E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 412 427 4.6E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 381 399 4.6E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 357 375 4.6E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 263 282 4.6E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 43 68 4.6E-42 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 Pfam PF01019 Gamma-glutamyltranspeptidase 36 537 4.9E-153 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS16240 178b4418541a1c76871fd0b81af4c81e 542 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 22 516 5.3E-112 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS21470 55d59c7f7d93db9898f29be02aa489c0 386 Pfam PF08878 Domain of unknown function (DUF1837) 82 319 7.7E-57 T 29-03-2018 IPR014976 Protein of unknown function DUF1837 CVS48_RS28925 ba36a6fd86be196c438cb22e597ee9cd 819 PIRSF PIRSF001227 3 817 2.5E-201 T 29-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 CVS48_RS28925 ba36a6fd86be196c438cb22e597ee9cd 819 SUPERFAMILY SSF56235 271 816 3.6E-203 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS28925 ba36a6fd86be196c438cb22e597ee9cd 819 SUPERFAMILY SSF56235 36 222 3.6E-203 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS28925 ba36a6fd86be196c438cb22e597ee9cd 819 Gene3D G3DSA:3.60.20.10 279 633 5.6E-89 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS28925 ba36a6fd86be196c438cb22e597ee9cd 819 Gene3D G3DSA:3.60.20.10 634 808 1.8E-29 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS28925 ba36a6fd86be196c438cb22e597ee9cd 819 Pfam PF01804 Penicillin amidase 40 805 2.7E-205 T 29-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CVS48_RS28925 ba36a6fd86be196c438cb22e597ee9cd 819 Gene3D G3DSA:1.10.439.10 10 174 5.4E-46 T 29-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CVS48_RS10885 c75cd2ca0f5fd2a9eca3a6ae3b06b9ae 259 Pfam PF02517 CAAX protease self-immunity 96 241 2.0E-7 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CVS48_RS28920 dba45a0304637f79760a87d78b5fa839 528 Pfam PF00884 Sulfatase 4 413 3.1E-52 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CVS48_RS28920 dba45a0304637f79760a87d78b5fa839 528 SUPERFAMILY SSF53649 148 514 1.44E-105 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS28920 dba45a0304637f79760a87d78b5fa839 528 SUPERFAMILY SSF53649 4 103 1.44E-105 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS28920 dba45a0304637f79760a87d78b5fa839 528 Gene3D G3DSA:3.40.720.10 2 371 4.7E-71 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS28920 dba45a0304637f79760a87d78b5fa839 528 Gene3D G3DSA:3.40.720.10 372 440 2.0E-9 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS28920 dba45a0304637f79760a87d78b5fa839 528 Pfam PF16347 Domain of unknown function (DUF4976) 419 512 9.5E-9 T 29-03-2018 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096 CVS48_RS28920 dba45a0304637f79760a87d78b5fa839 528 Gene3D G3DSA:3.30.1120.10 450 526 7.5E-8 T 29-03-2018 CVS48_RS17710 3618a6ef9e5670db5c08dd11aed4fae9 339 PRINTS PR01270 Histone deacetylase superfamily signature 153 176 3.3E-16 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS17710 3618a6ef9e5670db5c08dd11aed4fae9 339 PRINTS PR01270 Histone deacetylase superfamily signature 185 200 3.3E-16 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS17710 3618a6ef9e5670db5c08dd11aed4fae9 339 PRINTS PR01270 Histone deacetylase superfamily signature 271 281 3.3E-16 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS17710 3618a6ef9e5670db5c08dd11aed4fae9 339 Gene3D G3DSA:3.40.800.20 1 339 2.8E-88 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS17710 3618a6ef9e5670db5c08dd11aed4fae9 339 SUPERFAMILY SSF52768 3 338 1.63E-87 T 29-03-2018 CVS48_RS17710 3618a6ef9e5670db5c08dd11aed4fae9 339 Pfam PF00850 Histone deacetylase domain 50 334 2.9E-66 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS17295 53dacf625d7169fbdaedc53ab586f3ad 207 Pfam PF02223 Thymidylate kinase 10 193 1.4E-46 T 29-03-2018 CVS48_RS17295 53dacf625d7169fbdaedc53ab586f3ad 207 Gene3D G3DSA:3.40.50.300 2 198 5.3E-48 T 29-03-2018 CVS48_RS17295 53dacf625d7169fbdaedc53ab586f3ad 207 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 4 193 1.1E-48 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CVS48_RS17295 53dacf625d7169fbdaedc53ab586f3ad 207 Hamap MF_00165 Thymidylate kinase [tmk]. 6 203 28.021 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CVS48_RS17295 53dacf625d7169fbdaedc53ab586f3ad 207 SUPERFAMILY SSF52540 1 195 8.17E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 SUPERFAMILY SSF53223 11 162 5.9E-49 T 29-03-2018 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 SMART SM01274 18 152 1.6E-74 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 Gene3D G3DSA:3.40.718.10 448 721 6.7E-54 T 29-03-2018 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 Pfam PF01515 Phosphate acetyl/butaryl transferase 430 750 1.9E-98 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 Gene3D G3DSA:3.40.50.10380 5 161 5.3E-33 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 Pfam PF03949 Malic enzyme, NAD binding domain 166 361 8.7E-24 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 PIRSF PIRSF036684 1 758 0.0 T 29-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 Gene3D G3DSA:3.40.50.720 162 447 3.6E-85 T 29-03-2018 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 SMART SM00919 164 401 5.3E-142 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 SUPERFAMILY SSF53659 430 753 8.22E-90 T 29-03-2018 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 Pfam PF00390 Malic enzyme, N-terminal domain 19 152 2.2E-26 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CVS48_RS27865 cc57864d06366ed20f7da3b1a5e1729f 765 SUPERFAMILY SSF51735 164 443 3.44E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS14095 d5919f2c13dc3758ccc22aae8ba85fdb 182 Gene3D G3DSA:2.30.180.10 35 182 3.1E-36 T 29-03-2018 IPR000782 FAS1 domain CVS48_RS14095 d5919f2c13dc3758ccc22aae8ba85fdb 182 SMART SM00554 70 182 2.0E-23 T 29-03-2018 IPR000782 FAS1 domain CVS48_RS14095 d5919f2c13dc3758ccc22aae8ba85fdb 182 SUPERFAMILY SSF82153 35 181 2.75E-38 T 29-03-2018 IPR000782 FAS1 domain CVS48_RS14095 d5919f2c13dc3758ccc22aae8ba85fdb 182 Pfam PF02469 Fasciclin domain 46 181 4.2E-31 T 29-03-2018 IPR000782 FAS1 domain CVS48_RS22385 73b014611f2a2f35e0a5d832aaad0433 215 SUPERFAMILY SSF159594 28 198 7.32E-34 T 29-03-2018 CVS48_RS22385 73b014611f2a2f35e0a5d832aaad0433 215 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 31 191 2.8E-42 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component CVS48_RS22385 73b014611f2a2f35e0a5d832aaad0433 215 Gene3D G3DSA:3.40.50.10610 18 208 4.4E-47 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component CVS48_RS09610 7ce92b9e89710b6ddf77290b3d331c5b 376 Pfam PF13515 Fusaric acid resistance protein-like 224 349 7.3E-22 T 29-03-2018 CVS48_RS27560 b66862989bb30ccba0544e769e4585bc 386 SUPERFAMILY SSF53756 1 369 2.03E-125 T 29-03-2018 CVS48_RS27560 b66862989bb30ccba0544e769e4585bc 386 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 367 5.7E-115 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CVS48_RS27560 b66862989bb30ccba0544e769e4585bc 386 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 367 6.5E-141 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CVS48_RS27560 b66862989bb30ccba0544e769e4585bc 386 Gene3D G3DSA:3.40.50.2000 1 215 2.0E-76 T 29-03-2018 CVS48_RS27560 b66862989bb30ccba0544e769e4585bc 386 Gene3D G3DSA:3.40.50.2000 216 354 4.1E-35 T 29-03-2018 CVS48_RS21035 bde7900c48b2e4fa2c154f4539160b0f 527 SUPERFAMILY SSF53850 21 504 2.9E-125 T 29-03-2018 CVS48_RS21035 bde7900c48b2e4fa2c154f4539160b0f 527 PIRSF PIRSF002741 9 518 4.3E-100 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS21035 bde7900c48b2e4fa2c154f4539160b0f 527 Gene3D G3DSA:3.90.76.10 32 174 1.8E-30 T 29-03-2018 CVS48_RS21035 bde7900c48b2e4fa2c154f4539160b0f 527 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 64 433 9.9E-89 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS21035 bde7900c48b2e4fa2c154f4539160b0f 527 Gene3D G3DSA:3.10.105.10 286 493 6.8E-52 T 29-03-2018 CVS48_RS21035 bde7900c48b2e4fa2c154f4539160b0f 527 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 70 91 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CVS48_RS21035 bde7900c48b2e4fa2c154f4539160b0f 527 Gene3D G3DSA:3.40.190.10 175 285 6.4E-28 T 29-03-2018 CVS48_RS02260 7aa39b6441762dafba28f6273cb510fc 641 Pfam PF00884 Sulfatase 272 538 7.4E-39 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CVS48_RS02260 7aa39b6441762dafba28f6273cb510fc 641 PIRSF PIRSF005091 15 597 1.7E-83 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like CVS48_RS02260 7aa39b6441762dafba28f6273cb510fc 641 SUPERFAMILY SSF53649 270 591 4.32E-62 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS02260 7aa39b6441762dafba28f6273cb510fc 641 Gene3D G3DSA:3.40.720.10 260 543 2.0E-47 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS26265 b70ee89d98b359f62589db1207ea288d 141 Gene3D G3DSA:1.10.490.10 6 141 1.4E-32 T 29-03-2018 CVS48_RS26265 b70ee89d98b359f62589db1207ea288d 141 SUPERFAMILY SSF46458 18 139 8.28E-35 T 29-03-2018 IPR009050 Globin-like CVS48_RS26265 b70ee89d98b359f62589db1207ea288d 141 Pfam PF01152 Bacterial-like globin 18 137 1.2E-40 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CVS48_RS26265 b70ee89d98b359f62589db1207ea288d 141 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 67 91 - T 29-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CVS48_RS06445 3e3d4b4ba3a37efed2e01cfa1a22d92c 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 317 1.9E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS06445 3e3d4b4ba3a37efed2e01cfa1a22d92c 355 Gene3D G3DSA:1.10.3470.10 15 338 3.9E-27 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS23500 7408ed8114e321132fcc9c7028c20059 266 SUPERFAMILY SSF51182 114 231 1.91E-13 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS23500 7408ed8114e321132fcc9c7028c20059 266 Gene3D G3DSA:2.60.120.10 112 242 2.5E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS06930 176a0429b7fa50a3bf185bb7e7b9a4b9 427 Pfam PF07399 Putative Na+/H+ antiporter 5 425 8.0E-182 T 29-03-2018 IPR009978 Putative Na+/H+ antiporter CVS48_RS02885 ca2fd8637b61a6c5aacb743c87dbb739 328 Gene3D G3DSA:3.90.79.10 25 245 1.2E-26 T 29-03-2018 CVS48_RS02885 ca2fd8637b61a6c5aacb743c87dbb739 328 Gene3D G3DSA:1.10.10.10 246 316 9.6E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02885 ca2fd8637b61a6c5aacb743c87dbb739 328 PIRSF PIRSF019423 12 327 2.3E-142 T 29-03-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein CVS48_RS02885 ca2fd8637b61a6c5aacb743c87dbb739 328 SUPERFAMILY SSF55811 34 144 5.27E-8 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS02885 ca2fd8637b61a6c5aacb743c87dbb739 328 SUPERFAMILY SSF46785 245 316 1.77E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18400 e80cdb53f090fc8642a019be4975dabf 535 Gene3D G3DSA:3.40.50.2000 12 269 3.7E-12 T 29-03-2018 CVS48_RS18400 e80cdb53f090fc8642a019be4975dabf 535 Gene3D G3DSA:3.40.50.2000 270 466 1.1E-37 T 29-03-2018 CVS48_RS18400 e80cdb53f090fc8642a019be4975dabf 535 Pfam PF08323 Starch synthase catalytic domain 5 239 4.7E-68 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CVS48_RS18400 e80cdb53f090fc8642a019be4975dabf 535 Hamap MF_00484 Glycogen synthase [glgA]. 3 484 37.717 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CVS48_RS18400 e80cdb53f090fc8642a019be4975dabf 535 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 4 483 1.2E-153 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CVS48_RS18400 e80cdb53f090fc8642a019be4975dabf 535 SUPERFAMILY SSF53756 5 483 1.67E-104 T 29-03-2018 CVS48_RS18400 e80cdb53f090fc8642a019be4975dabf 535 Pfam PF00534 Glycosyl transferases group 1 291 453 1.6E-15 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS08860 23cf62dc1dd83e508c8c9d0225e117d0 415 Gene3D G3DSA:3.20.20.140 350 392 4.6E-9 T 29-03-2018 CVS48_RS08860 23cf62dc1dd83e508c8c9d0225e117d0 415 SUPERFAMILY SSF51338 352 411 7.64E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS08860 23cf62dc1dd83e508c8c9d0225e117d0 415 Gene3D G3DSA:2.30.40.10 1 68 5.5E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS08860 23cf62dc1dd83e508c8c9d0225e117d0 415 Pfam PF01979 Amidohydrolase family 54 390 4.2E-37 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS08860 23cf62dc1dd83e508c8c9d0225e117d0 415 Gene3D G3DSA:3.20.20.140 69 349 8.6E-46 T 29-03-2018 CVS48_RS08860 23cf62dc1dd83e508c8c9d0225e117d0 415 SUPERFAMILY SSF51556 58 368 1.26E-87 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS08860 23cf62dc1dd83e508c8c9d0225e117d0 415 SUPERFAMILY SSF51338 3 57 3.36E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS26100 447cef2e6612e42f1458f90e17b8372f 233 Pfam PF11254 Protein of unknown function (DUF3053) 12 227 1.0E-72 T 29-03-2018 IPR021413 Protein of unknown function DUF3053 CVS48_RS00550 b76e3d4675b4cc3d0a9de2c5d78f7e9c 156 Gene3D G3DSA:3.10.180.10 1 117 4.6E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS00550 b76e3d4675b4cc3d0a9de2c5d78f7e9c 156 SUPERFAMILY SSF54593 2 119 3.89E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS03980 a9dbd41d4af1da68100a9199fb406847 245 SUPERFAMILY SSF52096 5 245 3.27E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS03980 a9dbd41d4af1da68100a9199fb406847 245 Gene3D G3DSA:3.90.226.10 4 210 2.7E-54 T 29-03-2018 CVS48_RS03980 a9dbd41d4af1da68100a9199fb406847 245 Gene3D G3DSA:1.10.12.10 211 245 6.3E-15 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS03980 a9dbd41d4af1da68100a9199fb406847 245 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 243 4.1E-39 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS02350 215bb769dc86ed1cf469287cb855d7a3 566 Pfam PF13193 AMP-binding enzyme C-terminal domain 477 551 2.2E-19 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS02350 215bb769dc86ed1cf469287cb855d7a3 566 Pfam PF00501 AMP-binding enzyme 35 468 6.7E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS02350 215bb769dc86ed1cf469287cb855d7a3 566 SUPERFAMILY SSF56801 24 559 1.2E-146 T 29-03-2018 CVS48_RS02350 215bb769dc86ed1cf469287cb855d7a3 566 Gene3D G3DSA:3.30.300.30 462 566 2.5E-27 T 29-03-2018 CVS48_RS02350 215bb769dc86ed1cf469287cb855d7a3 566 ProSitePatterns PS00455 Putative AMP-binding domain signature. 215 226 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS02350 215bb769dc86ed1cf469287cb855d7a3 566 Gene3D G3DSA:2.30.38.10 378 461 2.6E-27 T 29-03-2018 CVS48_RS02350 215bb769dc86ed1cf469287cb855d7a3 566 Gene3D G3DSA:3.40.50.980 221 377 2.3E-38 T 29-03-2018 CVS48_RS02350 215bb769dc86ed1cf469287cb855d7a3 566 Gene3D G3DSA:3.40.50.980 26 220 1.0E-43 T 29-03-2018 CVS48_RS17020 129e814b179a48c422117cc87d642b93 447 Pfam PF02120 Flagellar hook-length control protein FliK 369 439 3.2E-12 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CVS48_RS15315 d610394311aee8030ac0ef80d633dbea 280 SUPERFAMILY SSF46785 2 110 3.34E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15315 d610394311aee8030ac0ef80d633dbea 280 Gene3D G3DSA:3.40.190.10 85 215 4.8E-19 T 29-03-2018 CVS48_RS15315 d610394311aee8030ac0ef80d633dbea 280 Gene3D G3DSA:1.10.10.10 2 83 3.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15315 d610394311aee8030ac0ef80d633dbea 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15315 d610394311aee8030ac0ef80d633dbea 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15315 d610394311aee8030ac0ef80d633dbea 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15315 d610394311aee8030ac0ef80d633dbea 280 SUPERFAMILY SSF53850 88 274 6.52E-28 T 29-03-2018 CVS48_RS15315 d610394311aee8030ac0ef80d633dbea 280 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.9E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS15315 d610394311aee8030ac0ef80d633dbea 280 Pfam PF03466 LysR substrate binding domain 87 272 1.3E-29 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS12535 88feea918c2cdb27a9fece8233f99826 229 SUPERFAMILY SSF46785 1 62 9.53E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12535 88feea918c2cdb27a9fece8233f99826 229 Gene3D G3DSA:1.10.10.10 1 64 1.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12535 88feea918c2cdb27a9fece8233f99826 229 Pfam PF13280 WYL domain 138 208 8.6E-12 T 29-03-2018 IPR026881 WYL domain CVS48_RS12535 88feea918c2cdb27a9fece8233f99826 229 Pfam PF08279 HTH domain 6 59 6.1E-16 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CVS48_RS24195 71e230d1770c3fe5ffeed660ed5007d0 71 Pfam PF07311 Dodecin 5 68 5.0E-31 T 29-03-2018 IPR009923 Dodecin CVS48_RS24195 71e230d1770c3fe5ffeed660ed5007d0 71 Gene3D G3DSA:3.30.1660.10 4 68 2.0E-32 T 29-03-2018 IPR025543 Dodecin-like CVS48_RS24195 71e230d1770c3fe5ffeed660ed5007d0 71 SUPERFAMILY SSF89807 5 69 1.14E-26 T 29-03-2018 IPR009923 Dodecin CVS48_RS00945 8b0062d57d880f5c10b24c4fcce1b214 175 Pfam PF11358 Protein of unknown function (DUF3158) 11 165 9.1E-75 T 29-03-2018 IPR021502 Protein of unknown function DUF3158 CVS48_RS27100 0d6b09ed2619d5c964e6d518ef44b67a 463 Gene3D G3DSA:3.30.1330.90 11 160 1.2E-54 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CVS48_RS27100 0d6b09ed2619d5c964e6d518ef44b67a 463 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 460 2.7E-209 T 29-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CVS48_RS27100 0d6b09ed2619d5c964e6d518ef44b67a 463 Pfam PF03313 Serine dehydratase alpha chain 186 457 6.2E-105 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CVS48_RS27100 0d6b09ed2619d5c964e6d518ef44b67a 463 Pfam PF03315 Serine dehydratase beta chain 4 156 2.0E-56 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CVS48_RS27100 0d6b09ed2619d5c964e6d518ef44b67a 463 SUPERFAMILY SSF143548 17 157 6.8E-45 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CVS48_RS27100 0d6b09ed2619d5c964e6d518ef44b67a 463 Gene3D G3DSA:1.10.4100.10 262 449 2.8E-30 T 29-03-2018 CVS48_RS02795 670a777a2c75896bda3a7f327b0077b1 171 Pfam PF00583 Acetyltransferase (GNAT) family 25 134 4.5E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS02795 670a777a2c75896bda3a7f327b0077b1 171 SUPERFAMILY SSF55729 3 141 2.23E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS02795 670a777a2c75896bda3a7f327b0077b1 171 Gene3D G3DSA:3.40.630.30 1 155 1.7E-22 T 29-03-2018 CVS48_RS15245 70a22da6e02fc92bcb788a96a02a73b5 196 Pfam PF04366 Las17-binding protein actin regulator 109 192 1.3E-14 T 29-03-2018 IPR007461 Ysc84 actin-binding domain CVS48_RS07540 f546e44390f45f03a32db6fa7893ddfc 446 Gene3D G3DSA:3.40.50.2300 16 163 1.3E-6 T 29-03-2018 CVS48_RS07540 f546e44390f45f03a32db6fa7893ddfc 446 SUPERFAMILY SSF53822 36 412 1.58E-49 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS07540 f546e44390f45f03a32db6fa7893ddfc 446 Pfam PF13458 Periplasmic binding protein 34 406 1.3E-76 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS07540 f546e44390f45f03a32db6fa7893ddfc 446 Gene3D G3DSA:3.40.50.2300 164 360 6.6E-23 T 29-03-2018 CVS48_RS00435 f0eabe9677b132faa1e8b9e6fe54c838 374 Pfam PF00762 Ferrochelatase 35 353 5.1E-106 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CVS48_RS00435 f0eabe9677b132faa1e8b9e6fe54c838 374 Hamap MF_00323 Ferrochelatase [hemH]. 34 354 37.652 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CVS48_RS00435 f0eabe9677b132faa1e8b9e6fe54c838 374 Gene3D G3DSA:3.40.50.1400 32 230 1.7E-50 T 29-03-2018 CVS48_RS00435 f0eabe9677b132faa1e8b9e6fe54c838 374 TIGRFAM TIGR00109 hemH: ferrochelatase 33 354 1.1E-86 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CVS48_RS00435 f0eabe9677b132faa1e8b9e6fe54c838 374 ProSitePatterns PS00534 Ferrochelatase signature. 223 242 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CVS48_RS00435 f0eabe9677b132faa1e8b9e6fe54c838 374 Gene3D G3DSA:3.40.50.1400 231 356 9.0E-30 T 29-03-2018 CVS48_RS00435 f0eabe9677b132faa1e8b9e6fe54c838 374 SUPERFAMILY SSF53800 34 359 9.03E-103 T 29-03-2018 CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 PIRSF PIRSF002869 1 516 6.9E-149 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 PRINTS PR01806 Virulence factor MviN signature 415 432 3.2E-76 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 PRINTS PR01806 Virulence factor MviN signature 363 382 3.2E-76 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 PRINTS PR01806 Virulence factor MviN signature 33 52 3.2E-76 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 PRINTS PR01806 Virulence factor MviN signature 159 180 3.2E-76 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 PRINTS PR01806 Virulence factor MviN signature 265 291 3.2E-76 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 PRINTS PR01806 Virulence factor MviN signature 135 159 3.2E-76 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 PRINTS PR01806 Virulence factor MviN signature 52 68 3.2E-76 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 473 19.583 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 Pfam PF03023 MviN-like protein 28 469 9.1E-131 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS22490 73c345d0a32b04829bfce236aff42773 519 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 507 3.0E-136 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS08000 7a078be92d506af81f99102206e4c507 181 Gene3D G3DSA:3.10.420.10 9 161 1.2E-46 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CVS48_RS08000 7a078be92d506af81f99102206e4c507 181 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 131 149 1.7E-27 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CVS48_RS08000 7a078be92d506af81f99102206e4c507 181 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 21 38 1.7E-27 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CVS48_RS08000 7a078be92d506af81f99102206e4c507 181 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 105 127 1.7E-27 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CVS48_RS08000 7a078be92d506af81f99102206e4c507 181 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 81 101 1.7E-27 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CVS48_RS08000 7a078be92d506af81f99102206e4c507 181 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 15 148 5.3E-43 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CVS48_RS08000 7a078be92d506af81f99102206e4c507 181 Hamap MF_00821 Protein-export protein SecB [secB]. 1 153 30.92 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CVS48_RS08000 7a078be92d506af81f99102206e4c507 181 Pfam PF02556 Preprotein translocase subunit SecB 14 151 1.9E-50 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CVS48_RS08000 7a078be92d506af81f99102206e4c507 181 SUPERFAMILY SSF54611 7 149 1.53E-46 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CVS48_RS04140 03b527fa09f505239d97b4ca8472337f 590 Gene3D G3DSA:2.30.42.10 487 582 2.6E-10 T 29-03-2018 CVS48_RS04140 03b527fa09f505239d97b4ca8472337f 590 PIRSF PIRSF016493 5 590 1.2E-206 T 29-03-2018 IPR024191 Peptidase M61 CVS48_RS04140 03b527fa09f505239d97b4ca8472337f 590 SUPERFAMILY SSF55486 227 437 3.22E-8 T 29-03-2018 CVS48_RS04140 03b527fa09f505239d97b4ca8472337f 590 SUPERFAMILY SSF50156 510 580 2.1E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS04140 03b527fa09f505239d97b4ca8472337f 590 Pfam PF05299 M61 glycyl aminopeptidase 289 405 1.6E-48 T 29-03-2018 IPR007963 Peptidase M61, catalytic domain CVS48_RS04140 03b527fa09f505239d97b4ca8472337f 590 Pfam PF13180 PDZ domain 504 578 2.9E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CVS48_RS04140 03b527fa09f505239d97b4ca8472337f 590 Gene3D G3DSA:1.10.390.10 279 474 5.4E-23 T 29-03-2018 CVS48_RS02740 49245fd6c160c93ce1223ff115dafd0c 114 Gene3D G3DSA:3.90.190.10 1 111 2.4E-5 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like CVS48_RS02740 49245fd6c160c93ce1223ff115dafd0c 114 Pfam PF04273 Putative phosphatase (DUF442) 7 113 1.5E-33 T 29-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 CVS48_RS02740 49245fd6c160c93ce1223ff115dafd0c 114 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 5 111 2.9E-31 T 29-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 CVS48_RS06070 902480fae02721d10d618f9804628bbb 339 SMART SM00382 57 257 1.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS06070 902480fae02721d10d618f9804628bbb 339 Pfam PF00005 ABC transporter 50 199 7.8E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS06070 902480fae02721d10d618f9804628bbb 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 249 335 1.5E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS06070 902480fae02721d10d618f9804628bbb 339 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS06070 902480fae02721d10d618f9804628bbb 339 SUPERFAMILY SSF52540 57 320 7.46E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06070 902480fae02721d10d618f9804628bbb 339 Gene3D G3DSA:3.40.50.300 9 338 7.2E-80 T 29-03-2018 CVS48_RS06070 902480fae02721d10d618f9804628bbb 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 315 1.3E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS09080 063ce3433d7539099f1b3b13e1b1fe13 360 SMART SM00937 63 178 1.8E-64 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CVS48_RS09080 063ce3433d7539099f1b3b13e1b1fe13 360 Gene3D G3DSA:3.30.160.20 209 292 1.2E-32 T 29-03-2018 CVS48_RS09080 063ce3433d7539099f1b3b13e1b1fe13 360 Gene3D G3DSA:1.20.58.410 2 94 2.3E-18 T 29-03-2018 CVS48_RS09080 063ce3433d7539099f1b3b13e1b1fe13 360 Pfam PF03462 PCRF domain 14 203 2.9E-72 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CVS48_RS09080 063ce3433d7539099f1b3b13e1b1fe13 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 40.819 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CVS48_RS09080 063ce3433d7539099f1b3b13e1b1fe13 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CVS48_RS09080 063ce3433d7539099f1b3b13e1b1fe13 360 Pfam PF00472 RF-1 domain 214 321 7.5E-43 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CVS48_RS09080 063ce3433d7539099f1b3b13e1b1fe13 360 SUPERFAMILY SSF75620 12 353 5.1E-137 T 29-03-2018 CVS48_RS09080 063ce3433d7539099f1b3b13e1b1fe13 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 356 8.0E-161 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CVS48_RS19520 5bc1afd29e05fbea745e13894d80182b 310 Pfam PF03755 YicC-like family, N-terminal region 2 153 2.2E-36 T 29-03-2018 IPR013527 YicC-like, N-terminal CVS48_RS19520 5bc1afd29e05fbea745e13894d80182b 310 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 310 3.3E-63 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 CVS48_RS19520 5bc1afd29e05fbea745e13894d80182b 310 Pfam PF08340 Domain of unknown function (DUF1732) 215 310 3.1E-33 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 CVS48_RS18600 9c8f7e3dd2000fc0521fdf44cb3bfd8e 107 Pfam PF12840 Helix-turn-helix domain 9 69 4.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18600 9c8f7e3dd2000fc0521fdf44cb3bfd8e 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.3E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS18600 9c8f7e3dd2000fc0521fdf44cb3bfd8e 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.3E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS18600 9c8f7e3dd2000fc0521fdf44cb3bfd8e 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.3E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS18600 9c8f7e3dd2000fc0521fdf44cb3bfd8e 107 SUPERFAMILY SSF46785 5 93 6.94E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18600 9c8f7e3dd2000fc0521fdf44cb3bfd8e 107 Gene3D G3DSA:1.10.10.10 1 83 1.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18600 9c8f7e3dd2000fc0521fdf44cb3bfd8e 107 SMART SM00418 8 88 7.5E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CVS48_RS17475 f9d13938aa76af735dd163e22bc517a1 149 Gene3D G3DSA:2.60.120.10 5 149 7.1E-29 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS17475 f9d13938aa76af735dd163e22bc517a1 149 Pfam PF07883 Cupin domain 58 121 4.4E-11 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS17475 f9d13938aa76af735dd163e22bc517a1 149 SUPERFAMILY SSF51182 30 147 1.78E-30 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 PRINTS PR00301 70kDa heat shock protein signature 3 16 9.7E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 PRINTS PR00301 70kDa heat shock protein signature 470 486 9.7E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 PRINTS PR00301 70kDa heat shock protein signature 199 209 9.7E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 PRINTS PR00301 70kDa heat shock protein signature 335 351 9.7E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 PRINTS PR00301 70kDa heat shock protein signature 366 386 9.7E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 PRINTS PR00301 70kDa heat shock protein signature 31 43 9.7E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 PRINTS PR00301 70kDa heat shock protein signature 54 62 9.7E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 PRINTS PR00301 70kDa heat shock protein signature 138 158 9.7E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 PRINTS PR00301 70kDa heat shock protein signature 389 408 9.7E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 637 37.082 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 SUPERFAMILY SSF53067 188 383 1.11E-68 T 29-03-2018 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 338 352 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 SUPERFAMILY SSF100934 508 610 7.65E-20 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 Gene3D G3DSA:3.30.420.40 1 197 7.4E-81 T 29-03-2018 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 604 5.4E-291 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 SUPERFAMILY SSF100920 385 541 1.57E-60 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 SUPERFAMILY SSF53067 4 184 3.4E-65 T 29-03-2018 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 Gene3D G3DSA:3.30.420.40 198 367 2.0E-48 T 29-03-2018 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 Gene3D G3DSA:1.20.1270.10 533 620 1.8E-21 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 Gene3D G3DSA:2.60.34.10 391 532 2.3E-66 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CVS48_RS00415 bc37edad60da171edfb76fa68b2a9a23 641 Pfam PF00012 Hsp70 protein 4 604 4.2E-266 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CVS48_RS06465 04e352efe4a0f5cd4a6c06399a5fd19b 390 Gene3D G3DSA:3.40.50.2300 6 198 6.2E-28 T 29-03-2018 CVS48_RS06465 04e352efe4a0f5cd4a6c06399a5fd19b 390 SUPERFAMILY SSF53822 24 386 6.73E-67 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS06465 04e352efe4a0f5cd4a6c06399a5fd19b 390 Gene3D G3DSA:3.40.50.2300 199 354 1.7E-19 T 29-03-2018 CVS48_RS06465 04e352efe4a0f5cd4a6c06399a5fd19b 390 Pfam PF13458 Periplasmic binding protein 25 362 1.8E-52 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS03790 3421cfa5f6dc5214d28426716929b2a7 377 Pfam PF13518 Helix-turn-helix domain 12 62 6.5E-12 T 29-03-2018 CVS48_RS03790 3421cfa5f6dc5214d28426716929b2a7 377 SUPERFAMILY SSF46689 11 115 2.15E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS03790 3421cfa5f6dc5214d28426716929b2a7 377 Pfam PF00665 Integrase core domain 134 257 2.1E-24 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CVS48_RS03790 3421cfa5f6dc5214d28426716929b2a7 377 SUPERFAMILY SSF53098 130 302 2.28E-36 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS03790 3421cfa5f6dc5214d28426716929b2a7 377 Gene3D G3DSA:1.10.10.10 10 65 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03790 3421cfa5f6dc5214d28426716929b2a7 377 Gene3D G3DSA:3.30.420.10 126 328 3.5E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS01070 fedfad6e8de0fc508affcfdb2405e4a0 397 Pfam PF00482 Type II secretion system (T2SS), protein F 64 188 2.9E-23 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS01070 fedfad6e8de0fc508affcfdb2405e4a0 397 Pfam PF00482 Type II secretion system (T2SS), protein F 267 388 1.5E-23 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS01070 fedfad6e8de0fc508affcfdb2405e4a0 397 PRINTS PR00812 Bacterial general secretion pathway protein F signature 377 396 3.6E-16 T 29-03-2018 IPR003004 GspF/PilC family CVS48_RS01070 fedfad6e8de0fc508affcfdb2405e4a0 397 PRINTS PR00812 Bacterial general secretion pathway protein F signature 59 71 3.6E-16 T 29-03-2018 IPR003004 GspF/PilC family CVS48_RS01070 fedfad6e8de0fc508affcfdb2405e4a0 397 PRINTS PR00812 Bacterial general secretion pathway protein F signature 361 375 3.6E-16 T 29-03-2018 IPR003004 GspF/PilC family CVS48_RS01070 fedfad6e8de0fc508affcfdb2405e4a0 397 PRINTS PR00812 Bacterial general secretion pathway protein F signature 160 188 3.6E-16 T 29-03-2018 IPR003004 GspF/PilC family CVS48_RS01070 fedfad6e8de0fc508affcfdb2405e4a0 397 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 160 188 - T 29-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 CVS48_RS07590 a05dfee8140de6f7e7ba7d93054400eb 165 SUPERFAMILY SSF110087 5 149 6.54E-48 T 29-03-2018 IPR007410 Copper chaperone PCuAC CVS48_RS07590 a05dfee8140de6f7e7ba7d93054400eb 165 Pfam PF04314 Copper chaperone PCu(A)C 32 141 1.1E-40 T 29-03-2018 IPR007410 Copper chaperone PCuAC CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 Gene3D G3DSA:3.30.420.40 1 144 2.8E-36 T 29-03-2018 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 317 9.4E-130 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 SUPERFAMILY SSF53067 2 122 7.12E-27 T 29-03-2018 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 339 60.458 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 310 8.8E-112 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.2E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.2E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 1.2E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 1.2E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.2E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 1.2E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 SUPERFAMILY SSF53067 102 312 8.42E-45 T 29-03-2018 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 Gene3D G3DSA:3.30.420.40 145 293 1.1E-15 T 29-03-2018 CVS48_RS19830 651ca4fe047bc9181a4f965e73ad7b6b 343 Pfam PF00814 Glycoprotease family 24 311 2.9E-97 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CVS48_RS18025 4c6563657291c089bcc74f1f2c6494c5 519 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 69 231 1.0E-16 T 29-03-2018 CVS48_RS20235 d27f17d5a3197068f87a5416ba94db50 229 SUPERFAMILY SSF161098 21 223 1.02E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20235 d27f17d5a3197068f87a5416ba94db50 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 223 3.5E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20235 d27f17d5a3197068f87a5416ba94db50 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 116 2.6E-22 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS20235 d27f17d5a3197068f87a5416ba94db50 229 Gene3D G3DSA:1.10.3720.10 6 228 9.8E-42 T 29-03-2018 CVS48_RS17320 55d299d095b527522347de8e569bcfd0 247 Gene3D G3DSA:3.40.190.10 168 247 2.0E-16 T 29-03-2018 CVS48_RS17320 55d299d095b527522347de8e569bcfd0 247 SMART SM00062 28 245 2.0E-69 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS17320 55d299d095b527522347de8e569bcfd0 247 SMART SM00079 28 244 3.6E-6 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CVS48_RS17320 55d299d095b527522347de8e569bcfd0 247 Gene3D G3DSA:3.40.190.10 19 167 1.8E-43 T 29-03-2018 CVS48_RS17320 55d299d095b527522347de8e569bcfd0 247 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 243 6.6E-63 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS17320 55d299d095b527522347de8e569bcfd0 247 SUPERFAMILY SSF53850 7 243 3.63E-73 T 29-03-2018 CVS48_RS15620 89fbf7e5b6633f3f02d981123843798b 242 SUPERFAMILY SSF55729 26 200 4.09E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS15620 89fbf7e5b6633f3f02d981123843798b 242 Pfam PF13302 Acetyltransferase (GNAT) domain 37 176 2.3E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS15620 89fbf7e5b6633f3f02d981123843798b 242 Gene3D G3DSA:3.40.630.30 20 231 3.0E-28 T 29-03-2018 CVS48_RS12630 ea75485536538c5b4f72c88e50ff906e 145 Pfam PF11162 Protein of unknown function (DUF2946) 13 143 1.3E-11 T 29-03-2018 IPR021333 Protein of unknown function DUF2946 CVS48_RS12590 6d48cc106d6946d802300fa06b273dd7 301 Gene3D G3DSA:3.40.190.10 92 175 2.7E-11 T 29-03-2018 CVS48_RS12590 6d48cc106d6946d802300fa06b273dd7 301 Pfam PF03466 LysR substrate binding domain 88 290 1.9E-47 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS12590 6d48cc106d6946d802300fa06b273dd7 301 Gene3D G3DSA:3.40.190.10 176 264 4.4E-28 T 29-03-2018 CVS48_RS12590 6d48cc106d6946d802300fa06b273dd7 301 SUPERFAMILY SSF46785 6 88 4.82E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12590 6d48cc106d6946d802300fa06b273dd7 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.0E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12590 6d48cc106d6946d802300fa06b273dd7 301 SUPERFAMILY SSF53850 89 296 4.34E-50 T 29-03-2018 CVS48_RS12590 6d48cc106d6946d802300fa06b273dd7 301 Gene3D G3DSA:1.10.10.10 3 84 1.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23645 d3550d45831deb5ca561cdd33d72e6eb 536 Gene3D G3DSA:1.20.120.20 71 498 0.017 T 29-03-2018 CVS48_RS23645 d3550d45831deb5ca561cdd33d72e6eb 536 Pfam PF15984 Bacterial collagen, middle region 60 183 4.3E-13 T 29-03-2018 IPR031929 Bacterial collagen-like protein, middle domain CVS48_RS23645 d3550d45831deb5ca561cdd33d72e6eb 536 Pfam PF15984 Bacterial collagen, middle region 194 342 2.7E-9 T 29-03-2018 IPR031929 Bacterial collagen-like protein, middle domain CVS48_RS07675 f444392e683a5862d66e66bac4ef53dc 300 Pfam PF00696 Amino acid kinase family 33 276 1.3E-43 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS07675 f444392e683a5862d66e66bac4ef53dc 300 Gene3D G3DSA:3.40.1160.10 2 300 7.3E-72 T 29-03-2018 CVS48_RS07675 f444392e683a5862d66e66bac4ef53dc 300 PRINTS PR00474 Glutamate 5-kinase family signature 64 78 4.3E-6 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS07675 f444392e683a5862d66e66bac4ef53dc 300 PRINTS PR00474 Glutamate 5-kinase family signature 199 226 4.3E-6 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS07675 f444392e683a5862d66e66bac4ef53dc 300 PRINTS PR00474 Glutamate 5-kinase family signature 249 269 4.3E-6 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CVS48_RS07675 f444392e683a5862d66e66bac4ef53dc 300 PIRSF PIRSF000728 18 299 1.1E-101 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS07675 f444392e683a5862d66e66bac4ef53dc 300 TIGRFAM TIGR00761 argB: acetylglutamate kinase 34 274 2.2E-73 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS07675 f444392e683a5862d66e66bac4ef53dc 300 Hamap MF_00082_B Acetylglutamate kinase [argB]. 31 299 35.447 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CVS48_RS07675 f444392e683a5862d66e66bac4ef53dc 300 SUPERFAMILY SSF53633 16 299 7.59E-90 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CVS48_RS00700 dd1d9fe1f657852496523a6eed913034 127 Pfam PF09686 Plasmid protein of unknown function (Plasmid_RAQPRD) 35 109 4.9E-28 T 29-03-2018 IPR019110 Uncharacterised protein family, RAQPRD CVS48_RS00700 dd1d9fe1f657852496523a6eed913034 127 TIGRFAM TIGR01690 ICE_RAQPRD: integrative conjugative element protein, RAQPRD family 18 110 3.8E-35 T 29-03-2018 IPR019110 Uncharacterised protein family, RAQPRD CVS48_RS28730 0dc80ac5892600618cfab8b45ec1c190 254 SMART SM00014 126 238 6.8E-10 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS28730 0dc80ac5892600618cfab8b45ec1c190 254 SUPERFAMILY SSF48317 51 248 3.92E-33 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS28730 0dc80ac5892600618cfab8b45ec1c190 254 Gene3D G3DSA:1.20.144.10 4 254 4.9E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS28730 0dc80ac5892600618cfab8b45ec1c190 254 Pfam PF01569 PAP2 superfamily 130 241 8.6E-19 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CVS48_RS23660 d7c45f4ad2f7566500de625e26476ff6 502 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 265 470 4.0E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS23660 d7c45f4ad2f7566500de625e26476ff6 502 Gene3D G3DSA:1.10.3720.10 147 470 2.5E-33 T 29-03-2018 CVS48_RS23660 d7c45f4ad2f7566500de625e26476ff6 502 SUPERFAMILY SSF161098 246 469 3.27E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS06390 6f36159980514a1cfe12d19c0f90e4cb 206 Pfam PF00573 Ribosomal protein L4/L1 family 19 203 9.8E-63 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CVS48_RS06390 6f36159980514a1cfe12d19c0f90e4cb 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 31.943 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06390 6f36159980514a1cfe12d19c0f90e4cb 206 Gene3D G3DSA:3.40.1370.10 145 204 1.3E-10 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CVS48_RS06390 6f36159980514a1cfe12d19c0f90e4cb 206 Gene3D G3DSA:3.40.1370.10 1 144 2.2E-46 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CVS48_RS06390 6f36159980514a1cfe12d19c0f90e4cb 206 SUPERFAMILY SSF52166 1 206 2.09E-70 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CVS48_RS06390 6f36159980514a1cfe12d19c0f90e4cb 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 203 4.2E-70 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS12085 62c96188481d11610075a45755a50ef7 564 SUPERFAMILY SSF51690 197 329 4.88E-30 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CVS48_RS12085 62c96188481d11610075a45755a50ef7 564 SUPERFAMILY SSF51690 387 550 4.88E-30 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CVS48_RS12085 62c96188481d11610075a45755a50ef7 564 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 199 501 1.4E-35 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CVS48_RS12085 62c96188481d11610075a45755a50ef7 564 Gene3D G3DSA:3.20.140.10 3 484 1.1E-74 T 29-03-2018 CVS48_RS17960 c3172e1c3f9b02a8ec37bc5048a6db53 148 SUPERFAMILY SSF46785 7 142 3.91E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17960 c3172e1c3f9b02a8ec37bc5048a6db53 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 80 114 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CVS48_RS17960 c3172e1c3f9b02a8ec37bc5048a6db53 148 Gene3D G3DSA:1.10.10.10 2 147 2.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17960 c3172e1c3f9b02a8ec37bc5048a6db53 148 SMART SM00347 34 148 4.9E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS17960 c3172e1c3f9b02a8ec37bc5048a6db53 148 Pfam PF12802 MarR family 40 105 7.3E-10 T 29-03-2018 CVS48_RS02985 d797c4175f8d75b3bb243b5511af3995 469 Pfam PF01551 Peptidase family M23 323 419 4.5E-34 T 29-03-2018 IPR016047 Peptidase M23 CVS48_RS02985 d797c4175f8d75b3bb243b5511af3995 469 Gene3D G3DSA:2.70.70.10 276 422 9.0E-42 T 29-03-2018 CVS48_RS02985 d797c4175f8d75b3bb243b5511af3995 469 SUPERFAMILY SSF51261 171 421 3.77E-73 T 29-03-2018 IPR011055 Duplicated hybrid motif CVS48_RS07495 ae45d70271f030df04f7c9f84ea4157d 154 Pfam PF01230 HIT domain 25 100 1.0E-11 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CVS48_RS07495 ae45d70271f030df04f7c9f84ea4157d 154 SUPERFAMILY SSF54197 5 118 4.93E-34 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CVS48_RS07495 ae45d70271f030df04f7c9f84ea4157d 154 Gene3D G3DSA:3.30.428.10 1 153 1.4E-26 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CVS48_RS07495 ae45d70271f030df04f7c9f84ea4157d 154 PIRSF PIRSF000714 5 150 7.4E-37 T 29-03-2018 IPR026026 Histidine triad hydrolase, Hint-type CVS48_RS26125 39aa798381891c655a207f8e9262e0ac 323 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 84 314 5.4E-50 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CVS48_RS26125 39aa798381891c655a207f8e9262e0ac 323 SUPERFAMILY SSF53756 9 320 1.19E-46 T 29-03-2018 CVS48_RS26125 39aa798381891c655a207f8e9262e0ac 323 Gene3D G3DSA:3.40.50.2000 168 323 9.5E-27 T 29-03-2018 CVS48_RS26125 39aa798381891c655a207f8e9262e0ac 323 Gene3D G3DSA:3.40.50.2000 5 144 3.6E-15 T 29-03-2018 CVS48_RS03960 36cf4bb95687608f92c80470ad2b7d35 409 SUPERFAMILY SSF89796 4 407 7.19E-146 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS03960 36cf4bb95687608f92c80470ad2b7d35 409 Pfam PF02515 CoA-transferase family III 8 386 2.1E-134 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS03960 36cf4bb95687608f92c80470ad2b7d35 409 Gene3D G3DSA:3.40.50.10540 2 408 1.9E-160 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS09505 68a786a7dfcc1c3ba000dc10f76b2d4e 268 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 265 1.3E-68 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CVS48_RS09505 68a786a7dfcc1c3ba000dc10f76b2d4e 268 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 265 24.0 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CVS48_RS09505 68a786a7dfcc1c3ba000dc10f76b2d4e 268 SUPERFAMILY SSF51735 4 158 3.55E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS09505 68a786a7dfcc1c3ba000dc10f76b2d4e 268 Gene3D G3DSA:3.40.50.720 1 162 5.2E-27 T 29-03-2018 CVS48_RS09505 68a786a7dfcc1c3ba000dc10f76b2d4e 268 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 97 9.4E-9 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CVS48_RS09505 68a786a7dfcc1c3ba000dc10f76b2d4e 268 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 265 2.1E-29 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CVS48_RS09505 68a786a7dfcc1c3ba000dc10f76b2d4e 268 Gene3D G3DSA:1.10.3730.10 163 268 2.2E-30 T 29-03-2018 CVS48_RS09505 68a786a7dfcc1c3ba000dc10f76b2d4e 268 PIRSF PIRSF000193 2 268 1.3E-60 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CVS48_RS09505 68a786a7dfcc1c3ba000dc10f76b2d4e 268 SUPERFAMILY SSF48179 161 266 1.87E-28 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS24165 6fadcde173820b9204fade049109b060 60 Pfam PF13318 Protein of unknown function (DUF4089) 9 58 2.7E-11 T 29-03-2018 IPR025148 Protein of unknown function DUF4089 CVS48_RS21065 db31de916370ba7f39fa838b79d453d5 429 Gene3D G3DSA:3.40.50.300 1 420 1.6E-29 T 29-03-2018 CVS48_RS21065 db31de916370ba7f39fa838b79d453d5 429 SMART SM00382 24 424 0.0019 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21065 db31de916370ba7f39fa838b79d453d5 429 Pfam PF13175 AAA ATPase domain 1 412 6.5E-25 T 29-03-2018 CVS48_RS21065 db31de916370ba7f39fa838b79d453d5 429 SUPERFAMILY SSF52540 1 181 2.73E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21065 db31de916370ba7f39fa838b79d453d5 429 SUPERFAMILY SSF52540 271 415 2.73E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS03565 ee277d1bf48651d24265e87e17fbc8e6 285 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 22 125 6.3E-26 T 29-03-2018 IPR010627 Peptidase A24A, N-terminal CVS48_RS03565 ee277d1bf48651d24265e87e17fbc8e6 285 Pfam PF01478 Type IV leader peptidase family 137 243 5.2E-24 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CVS48_RS03565 ee277d1bf48651d24265e87e17fbc8e6 285 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 201 211 3.2E-24 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CVS48_RS03565 ee277d1bf48651d24265e87e17fbc8e6 285 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 224 239 3.2E-24 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CVS48_RS03565 ee277d1bf48651d24265e87e17fbc8e6 285 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 144 161 3.2E-24 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CVS48_RS03565 ee277d1bf48651d24265e87e17fbc8e6 285 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 212 223 3.2E-24 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CVS48_RS19860 f64e89e6b70275bfb55b89ce437be4c1 272 Gene3D G3DSA:3.40.190.10 34 119 1.5E-6 T 29-03-2018 CVS48_RS19860 f64e89e6b70275bfb55b89ce437be4c1 272 SUPERFAMILY SSF53850 32 254 1.78E-18 T 29-03-2018 CVS48_RS19860 f64e89e6b70275bfb55b89ce437be4c1 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 253 1.2E-15 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS19860 f64e89e6b70275bfb55b89ce437be4c1 272 SMART SM00062 39 257 5.5E-4 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS19860 f64e89e6b70275bfb55b89ce437be4c1 272 Gene3D G3DSA:3.40.190.10 120 211 3.3E-9 T 29-03-2018 CVS48_RS13835 2f7516d9683685069c96e67ae2f3b590 440 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 355 375 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CVS48_RS13835 2f7516d9683685069c96e67ae2f3b590 440 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 28 430 1.4E-104 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CVS48_RS13835 2f7516d9683685069c96e67ae2f3b590 440 Pfam PF00860 Permease family 32 408 1.3E-86 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS12585 349241328e5617d3f6cde4d3617215fe 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 27.935 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CVS48_RS12585 349241328e5617d3f6cde4d3617215fe 160 Gene3D G3DSA:3.30.70.860 95 159 2.4E-30 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain CVS48_RS12585 349241328e5617d3f6cde4d3617215fe 160 Gene3D G3DSA:3.30.70.990 10 94 4.0E-28 T 29-03-2018 IPR035570 UPF0234 N-terminal domain CVS48_RS12585 349241328e5617d3f6cde4d3617215fe 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 8.3E-60 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CVS48_RS12585 349241328e5617d3f6cde4d3617215fe 160 SUPERFAMILY SSF89963 89 160 1.05E-27 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CVS48_RS12585 349241328e5617d3f6cde4d3617215fe 160 SUPERFAMILY SSF89963 2 83 1.23E-27 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CVS48_RS05350 48dffcc876d7558c7eca3154cc55f8c7 486 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 471 2.3E-60 T 29-03-2018 IPR010352 Protein of unknown function DUF945 CVS48_RS10985 6fe6785a5f68db4e6b4abd85c0e867b2 732 Pfam PF05506 Domain of unknown function (DUF756) 532 622 9.8E-24 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CVS48_RS10985 6fe6785a5f68db4e6b4abd85c0e867b2 732 Pfam PF05506 Domain of unknown function (DUF756) 631 714 2.5E-18 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CVS48_RS10985 6fe6785a5f68db4e6b4abd85c0e867b2 732 Pfam PF04185 Phosphoesterase family 49 460 1.3E-110 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 CVS48_RS10985 6fe6785a5f68db4e6b4abd85c0e867b2 732 Gene3D G3DSA:3.40.720.10 128 465 4.2E-23 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS10985 6fe6785a5f68db4e6b4abd85c0e867b2 732 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 6 728 9.1E-278 T 29-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CVS48_RS27540 dab8dfaed2d3add2b0bd80e6885eb729 242 Gene3D G3DSA:3.40.50.150 2 242 3.5E-50 T 29-03-2018 CVS48_RS27540 dab8dfaed2d3add2b0bd80e6885eb729 242 Pfam PF13489 Methyltransferase domain 57 213 1.9E-26 T 29-03-2018 CVS48_RS27540 dab8dfaed2d3add2b0bd80e6885eb729 242 SUPERFAMILY SSF53335 6 226 5.88E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS27540 dab8dfaed2d3add2b0bd80e6885eb729 242 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 19 237 1.7E-86 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 CVS48_RS27540 dab8dfaed2d3add2b0bd80e6885eb729 242 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 17 242 37.946 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 CVS48_RS02385 4fbc22158f6574d9fa37a8b358f69369 203 SUPERFAMILY SSF110857 34 147 5.76E-13 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CVS48_RS02385 4fbc22158f6574d9fa37a8b358f69369 203 Pfam PF04752 ChaC-like protein 34 197 1.2E-43 T 29-03-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 Reactome: R-HSA-174403 CVS48_RS02385 4fbc22158f6574d9fa37a8b358f69369 203 Gene3D G3DSA:3.10.490.10 29 192 2.6E-30 T 29-03-2018 CVS48_RS12370 42f4c5204de40e940b6a48871e9d99dd 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 4.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS12370 42f4c5204de40e940b6a48871e9d99dd 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 4.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS12370 42f4c5204de40e940b6a48871e9d99dd 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 4.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS12370 42f4c5204de40e940b6a48871e9d99dd 158 SMART SM00347 36 136 5.3E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS12370 42f4c5204de40e940b6a48871e9d99dd 158 SUPERFAMILY SSF46785 15 146 7.1E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12370 42f4c5204de40e940b6a48871e9d99dd 158 Pfam PF13463 Winged helix DNA-binding domain 47 109 1.6E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS12370 42f4c5204de40e940b6a48871e9d99dd 158 Gene3D G3DSA:1.10.10.10 17 149 2.6E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09800 b66848fb09b7167c6859c592880f1bd3 436 SUPERFAMILY SSF103473 12 429 4.05E-81 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS09800 b66848fb09b7167c6859c592880f1bd3 436 Gene3D G3DSA:1.20.1250.20 222 432 1.3E-21 T 29-03-2018 CVS48_RS09800 b66848fb09b7167c6859c592880f1bd3 436 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 28 428 7.2E-125 T 29-03-2018 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 CVS48_RS09800 b66848fb09b7167c6859c592880f1bd3 436 Gene3D G3DSA:1.20.1250.20 13 211 1.9E-39 T 29-03-2018 CVS48_RS09800 b66848fb09b7167c6859c592880f1bd3 436 Pfam PF07690 Major Facilitator Superfamily 26 391 1.9E-56 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS09800 b66848fb09b7167c6859c592880f1bd3 436 PIRSF PIRSF002808 3 436 4.3E-38 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 SMART SM00345 25 84 4.6E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 SUPERFAMILY SSF48008 104 236 2.88E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 2.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 2.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 Gene3D G3DSA:1.10.10.10 6 86 2.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 Pfam PF07729 FCD domain 106 232 8.8E-23 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 SMART SM00895 106 232 1.8E-21 T 29-03-2018 IPR011711 GntR, C-terminal CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 SUPERFAMILY SSF46785 20 88 1.17E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 84 5.4E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS03670 8063d4113b001b620cef51f9ac2c96b7 242 Gene3D G3DSA:1.20.120.530 104 242 2.3E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CVS48_RS23195 962fb28c6e7512f928bdc720fb6ec181 478 Gene3D G3DSA:3.40.50.150 2 173 5.4E-31 T 29-03-2018 CVS48_RS23195 962fb28c6e7512f928bdc720fb6ec181 478 Gene3D G3DSA:3.40.50.300 259 458 4.8E-40 T 29-03-2018 CVS48_RS23195 962fb28c6e7512f928bdc720fb6ec181 478 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 260 447 26.19 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CVS48_RS23195 962fb28c6e7512f928bdc720fb6ec181 478 SUPERFAMILY SSF52540 263 454 1.42E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23195 962fb28c6e7512f928bdc720fb6ec181 478 Pfam PF13500 AAA domain 263 450 9.1E-54 T 29-03-2018 CVS48_RS23195 962fb28c6e7512f928bdc720fb6ec181 478 SUPERFAMILY SSF53335 19 194 1.72E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS23195 962fb28c6e7512f928bdc720fb6ec181 478 Pfam PF13649 Methyltransferase domain 50 143 8.5E-17 T 29-03-2018 CVS48_RS23195 962fb28c6e7512f928bdc720fb6ec181 478 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 264 418 1.9E-41 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CVS48_RS00690 72d4f758996b00d0b4fe222482d09b2d 119 Pfam PF11190 Protein of unknown function (DUF2976) 32 118 1.5E-32 T 29-03-2018 IPR021356 Integrating conjugative element protein PFL4702 CVS48_RS00690 72d4f758996b00d0b4fe222482d09b2d 119 TIGRFAM TIGR03745 conj_TIGR03745: integrating conjugative element membrane protein, PFL_4702 family 16 119 1.1E-44 T 29-03-2018 IPR021356 Integrating conjugative element protein PFL4702 CVS48_RS00860 f0c09eb7b894e9c09336441a75f03c24 116 Pfam PF02411 MerT mercuric transport protein 1 116 1.0E-59 T 29-03-2018 IPR003457 Mercuric transport protein MerT GO:0015097|GO:0015694|GO:0016020 CVS48_RS00860 f0c09eb7b894e9c09336441a75f03c24 116 Gene3D G3DSA:1.10.287.910 16 68 7.5E-19 T 29-03-2018 CVS48_RS21025 fd359ce5d7b8cd5c6dd294fafe04a87c 336 SMART SM00382 41 248 6.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21025 fd359ce5d7b8cd5c6dd294fafe04a87c 336 Pfam PF00005 ABC transporter 33 190 3.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS21025 fd359ce5d7b8cd5c6dd294fafe04a87c 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 324 1.8E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS21025 fd359ce5d7b8cd5c6dd294fafe04a87c 336 SUPERFAMILY SSF52540 13 261 7.1E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21025 fd359ce5d7b8cd5c6dd294fafe04a87c 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 306 1.7E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CVS48_RS21025 fd359ce5d7b8cd5c6dd294fafe04a87c 336 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS21025 fd359ce5d7b8cd5c6dd294fafe04a87c 336 Gene3D G3DSA:3.40.50.300 10 335 9.2E-74 T 29-03-2018 CVS48_RS15035 22f7ef47ba71ef9ca124d0e310dc1c59 593 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 127 137 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS15035 22f7ef47ba71ef9ca124d0e310dc1c59 593 SUPERFAMILY SSF52016 381 577 9.42E-46 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS15035 22f7ef47ba71ef9ca124d0e310dc1c59 593 SUPERFAMILY SSF143975 6 378 1.44E-114 T 29-03-2018 CVS48_RS15035 22f7ef47ba71ef9ca124d0e310dc1c59 593 Gene3D G3DSA:3.40.50.720 49 454 0.0011 T 29-03-2018 CVS48_RS15035 22f7ef47ba71ef9ca124d0e310dc1c59 593 Pfam PF00920 Dehydratase family 44 570 2.1E-154 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CVS48_RS09850 8cac0f601968ef44dd3efadd5ce9aebd 148 SMART SM00257 94 145 4.7E-10 T 29-03-2018 IPR018392 LysM domain CVS48_RS09850 8cac0f601968ef44dd3efadd5ce9aebd 148 Pfam PF01476 LysM domain 95 145 1.4E-12 T 29-03-2018 IPR018392 LysM domain CVS48_RS09850 8cac0f601968ef44dd3efadd5ce9aebd 148 Gene3D G3DSA:3.10.350.10 88 148 1.4E-16 T 29-03-2018 CVS48_RS09850 8cac0f601968ef44dd3efadd5ce9aebd 148 Pfam PF04972 BON domain 22 86 1.9E-10 T 29-03-2018 IPR007055 BON domain CVS48_RS09850 8cac0f601968ef44dd3efadd5ce9aebd 148 SUPERFAMILY SSF54106 93 145 7.32E-8 T 29-03-2018 IPR018392 LysM domain CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 Pfam PF03144 Elongation factor Tu domain 2 310 376 3.2E-7 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 524 50.916 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 Gene3D G3DSA:3.40.50.300 4 266 6.0E-39 T 29-03-2018 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 PRINTS PR00315 GTP-binding elongation factor signature 134 143 1.2E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 PRINTS PR00315 GTP-binding elongation factor signature 62 70 1.2E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 PRINTS PR00315 GTP-binding elongation factor signature 98 109 1.2E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.2E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 PRINTS PR00315 GTP-binding elongation factor signature 82 92 1.2E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 SUPERFAMILY SSF54980 388 459 2.09E-16 T 29-03-2018 IPR035647 EF-G domain III/V-like CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 SUPERFAMILY SSF52540 7 273 1.47E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 Pfam PF00009 Elongation factor Tu GTP binding domain 10 273 7.4E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 Gene3D G3DSA:2.40.30.10 267 380 3.2E-18 T 29-03-2018 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 144 1.2E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 526 1.9E-209 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 Gene3D G3DSA:3.30.70.870 385 461 2.1E-12 T 29-03-2018 CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 SUPERFAMILY SSF50447 257 387 1.08E-27 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CVS48_RS05370 c7b174d4fac0a0c96e8d19217d2d8f0b 535 Pfam PF16658 Class II release factor RF3, C-terminal domain 383 511 1.4E-43 T 29-03-2018 IPR032090 Peptide chain release factor 3, C-terminal CVS48_RS09050 4318065e1e83a0b3dec3791bc1f05622 486 Pfam PF05893 Acyl-CoA reductase (LuxC) 62 466 1.1E-85 T 29-03-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 CVS48_RS09050 4318065e1e83a0b3dec3791bc1f05622 486 PIRSF PIRSF009414 16 483 2.0E-74 T 29-03-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 CVS48_RS09050 4318065e1e83a0b3dec3791bc1f05622 486 Gene3D G3DSA:3.40.605.10 28 306 5.1E-13 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS09050 4318065e1e83a0b3dec3791bc1f05622 486 SUPERFAMILY SSF53720 33 438 5.73E-8 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 Gene3D G3DSA:3.40.800.10 14 317 4.3E-79 T 29-03-2018 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 PRINTS PR00116 Arginase signature 237 266 8.0E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 PRINTS PR00116 Arginase signature 108 123 8.0E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 PRINTS PR00116 Arginase signature 189 207 8.0E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 PRINTS PR00116 Arginase signature 272 286 8.0E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 PRINTS PR00116 Arginase signature 135 162 8.0E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 ProSitePatterns PS01053 Arginase family signature. 240 261 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 Pfam PF00491 Arginase family 18 310 2.7E-74 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 PIRSF PIRSF036979 7 314 2.1E-27 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 TIGRFAM TIGR01229 rocF_arginase: arginase 20 314 7.9E-85 T 29-03-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 CVS48_RS19195 1467085631913dfb6abc2e3ca67f119f 320 SUPERFAMILY SSF52768 19 315 1.98E-88 T 29-03-2018 CVS48_RS12305 32c49af3aa9f12dceeeb31aefaa2b1f1 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 121 5.8E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS12305 32c49af3aa9f12dceeeb31aefaa2b1f1 129 SUPERFAMILY SSF54593 7 126 5.5E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS12305 32c49af3aa9f12dceeeb31aefaa2b1f1 129 Gene3D G3DSA:3.10.180.10 1 129 1.1E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS24865 87a914d7f836c94f36178266d6d684dd 357 SUPERFAMILY SSF51306 210 344 8.37E-14 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CVS48_RS24865 87a914d7f836c94f36178266d6d684dd 357 Gene3D G3DSA:2.10.109.10 217 348 2.9E-12 T 29-03-2018 CVS48_RS06885 b231f0ff3562b9ee13db855ae23f0fff 138 Pfam PF06476 Protein of unknown function (DUF1090) 25 129 4.5E-33 T 29-03-2018 IPR009468 Protein of unknown function DUF1090 CVS48_RS18000 819a5414d3bf154e956d4499961459d6 138 SUPERFAMILY SSF50249 4 120 3.26E-7 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS18000 819a5414d3bf154e956d4499961459d6 138 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 4 26 6.7E-6 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CVS48_RS23305 3a113d6b31609ccdb89cd52f649bf7ea 228 Gene3D G3DSA:1.10.3720.10 1 216 2.1E-38 T 29-03-2018 CVS48_RS23305 3a113d6b31609ccdb89cd52f649bf7ea 228 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 212 8.4E-72 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CVS48_RS23305 3a113d6b31609ccdb89cd52f649bf7ea 228 SUPERFAMILY SSF161098 4 214 1.44E-51 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS23305 3a113d6b31609ccdb89cd52f649bf7ea 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 24 210 1.6E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS15485 afccb5a3f131e22ac1426b645cebff49 249 SUPERFAMILY SSF53901 20 164 3.55E-5 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS15485 afccb5a3f131e22ac1426b645cebff49 249 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 22 245 1.3E-71 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CVS48_RS23070 3ccf6d5326c34b9f99304d6691f1b79d 360 Pfam PF10503 Esterase PHB depolymerase 77 277 6.9E-62 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CVS48_RS23070 3ccf6d5326c34b9f99304d6691f1b79d 360 Gene3D G3DSA:3.40.50.1820 12 348 5.6E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS23070 3ccf6d5326c34b9f99304d6691f1b79d 360 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 82 278 5.3E-37 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CVS48_RS23070 3ccf6d5326c34b9f99304d6691f1b79d 360 SUPERFAMILY SSF53474 70 276 9.59E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS04355 7b207e8d58ec16507f52b79392351856 326 Gene3D G3DSA:2.130.10.10 9 126 6.6E-16 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS04355 7b207e8d58ec16507f52b79392351856 326 Gene3D G3DSA:2.130.10.10 127 213 9.7E-13 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS04355 7b207e8d58ec16507f52b79392351856 326 Gene3D G3DSA:2.130.10.10 214 323 1.5E-19 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS04355 7b207e8d58ec16507f52b79392351856 326 Pfam PF10282 Lactonase, 7-bladed beta-propeller 98 301 5.2E-8 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CVS48_RS04355 7b207e8d58ec16507f52b79392351856 326 SUPERFAMILY SSF50974 6 320 4.32E-69 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CVS48_RS15080 4958a618c6711aeb0e65e98781a8c87a 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 276 1.7E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS15080 4958a618c6711aeb0e65e98781a8c87a 279 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 4 50 1.0E-5 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS15080 4958a618c6711aeb0e65e98781a8c87a 279 SUPERFAMILY SSF161098 70 256 1.83E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS15080 4958a618c6711aeb0e65e98781a8c87a 279 Gene3D G3DSA:1.10.3720.10 1 264 6.3E-40 T 29-03-2018 CVS48_RS21250 6d39450c28c9bf9ca05af6e57606cd44 442 SUPERFAMILY SSF53335 80 383 2.41E-76 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS21250 6d39450c28c9bf9ca05af6e57606cd44 442 Gene3D G3DSA:3.40.50.150 150 429 7.6E-65 T 29-03-2018 CVS48_RS21250 6d39450c28c9bf9ca05af6e57606cd44 442 Pfam PF02353 Mycolic acid cyclopropane synthetase 157 424 1.8E-83 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS21250 6d39450c28c9bf9ca05af6e57606cd44 442 PIRSF PIRSF003085 45 441 3.7E-122 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CVS48_RS04135 9f1f35bd4a41f4b3a396fb0d67045651 258 Gene3D G3DSA:3.90.226.10 1 218 9.9E-76 T 29-03-2018 CVS48_RS04135 9f1f35bd4a41f4b3a396fb0d67045651 258 SUPERFAMILY SSF52096 1 258 2.49E-92 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS04135 9f1f35bd4a41f4b3a396fb0d67045651 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS04135 9f1f35bd4a41f4b3a396fb0d67045651 258 Gene3D G3DSA:1.10.12.10 219 256 8.8E-25 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS04135 9f1f35bd4a41f4b3a396fb0d67045651 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 7.6E-82 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS03045 1dc5ca08b2d19920a99485a013ab71e6 364 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 45 324 6.9E-39 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS03045 1dc5ca08b2d19920a99485a013ab71e6 364 PIRSF PIRSF039026 1 358 1.2E-88 T 29-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CVS48_RS03045 1dc5ca08b2d19920a99485a013ab71e6 364 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 27 0.0012 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CVS48_RS22030 34666880376c56e8df90bfb3b1f26679 384 SUPERFAMILY SSF51419 21 244 4.45E-36 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS22030 34666880376c56e8df90bfb3b1f26679 384 Pfam PF01168 Alanine racemase, N-terminal domain 21 246 3.9E-33 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CVS48_RS22030 34666880376c56e8df90bfb3b1f26679 384 SMART SM01119 261 368 2.4E-41 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CVS48_RS22030 34666880376c56e8df90bfb3b1f26679 384 Pfam PF14031 Putative serine dehydratase domain 261 367 1.1E-20 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CVS48_RS22030 34666880376c56e8df90bfb3b1f26679 384 Gene3D G3DSA:3.20.20.10 14 248 1.5E-41 T 29-03-2018 IPR029066 PLP-binding barrel CVS48_RS04565 d691ddc2225200d1feaa577a28216b3b 326 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 260 6.3E-32 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS04565 d691ddc2225200d1feaa577a28216b3b 326 Gene3D G3DSA:2.40.50.100 46 182 1.4E-8 T 29-03-2018 CVS48_RS04565 d691ddc2225200d1feaa577a28216b3b 326 SUPERFAMILY SSF111369 42 254 9.55E-16 T 29-03-2018 CVS48_RS04565 d691ddc2225200d1feaa577a28216b3b 326 Pfam PF13437 HlyD family secretion protein 147 240 1.3E-11 T 29-03-2018 CVS48_RS07635 b0f4ecd971fb0764f9586fcdc0d9ab2c 294 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 10 282 1.5E-53 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CVS48_RS07635 b0f4ecd971fb0764f9586fcdc0d9ab2c 294 PIRSF PIRSF038471 7 288 2.7E-72 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CVS48_RS07635 b0f4ecd971fb0764f9586fcdc0d9ab2c 294 Pfam PF04085 rod shape-determining protein MreC 128 274 4.7E-36 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CVS48_RS06935 114347b8d5ffeabc7ed1f3518964d01b 110 SMART SM00834 1 42 1.2E-17 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CVS48_RS06935 114347b8d5ffeabc7ed1f3518964d01b 110 Pfam PF09723 Zinc ribbon domain 1 41 1.1E-15 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CVS48_RS06935 114347b8d5ffeabc7ed1f3518964d01b 110 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 1.6E-21 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 231 243 2.4E-5 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 326 343 2.4E-5 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 2.4E-5 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 54 65 2.4E-5 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 157 168 2.4E-5 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 Pfam PF13609 Gram-negative porin 7 346 1.7E-56 T 29-03-2018 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 PRINTS PR00184 Neisseria sp. porin signature 156 173 2.2E-8 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 PRINTS PR00184 Neisseria sp. porin signature 323 347 2.2E-8 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 PRINTS PR00184 Neisseria sp. porin signature 56 81 2.2E-8 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 SUPERFAMILY SSF56935 22 369 2.72E-73 T 29-03-2018 CVS48_RS12070 c68538cb50923cb376a6ac6a4f086ddc 369 Gene3D G3DSA:2.40.160.10 8 369 2.0E-70 T 29-03-2018 CVS48_RS28170 6818f45a29b40d227d0fb9aff07db311 169 Pfam PF00877 NlpC/P60 family 50 156 4.8E-29 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CVS48_RS28170 6818f45a29b40d227d0fb9aff07db311 169 SUPERFAMILY SSF54001 38 157 1.01E-39 T 29-03-2018 CVS48_RS28170 6818f45a29b40d227d0fb9aff07db311 169 Gene3D G3DSA:3.90.1720.10 31 169 7.7E-39 T 29-03-2018 CVS48_RS08750 d6cb3e9fef41b3a7ca25772748b6d750 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 300 8.5E-37 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS08750 d6cb3e9fef41b3a7ca25772748b6d750 324 Gene3D G3DSA:1.10.3470.10 6 306 5.2E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS04770 ae96b61cf1c516d1ec2ac6cd9e1303da 333 Pfam PF12281 Nucleotidyltransferase 118 318 4.8E-52 T 29-03-2018 IPR022550 Nucleotidyltransferase 8 CVS48_RS04770 ae96b61cf1c516d1ec2ac6cd9e1303da 333 Gene3D G3DSA:1.10.10.10 106 333 0.5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04770 ae96b61cf1c516d1ec2ac6cd9e1303da 333 Gene3D G3DSA:1.10.10.10 46 105 0.27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22180 3d4dcfe188e91ec9819140dc170505f3 379 SUPERFAMILY SSF55031 181 290 7.18E-31 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS22180 3d4dcfe188e91ec9819140dc170505f3 379 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 7 375 4.0E-162 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CVS48_RS22180 3d4dcfe188e91ec9819140dc170505f3 379 SUPERFAMILY SSF53187 294 375 1.84E-69 T 29-03-2018 CVS48_RS22180 3d4dcfe188e91ec9819140dc170505f3 379 SUPERFAMILY SSF53187 5 180 1.84E-69 T 29-03-2018 CVS48_RS22180 3d4dcfe188e91ec9819140dc170505f3 379 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 4 377 52.275 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CVS48_RS22180 3d4dcfe188e91ec9819140dc170505f3 379 Gene3D G3DSA:3.40.630.10 1 183 2.6E-36 T 29-03-2018 CVS48_RS22180 3d4dcfe188e91ec9819140dc170505f3 379 Pfam PF01546 Peptidase family M20/M25/M40 65 374 2.9E-46 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CVS48_RS22180 3d4dcfe188e91ec9819140dc170505f3 379 Gene3D G3DSA:3.30.70.360 184 293 8.6E-29 T 29-03-2018 CVS48_RS22180 3d4dcfe188e91ec9819140dc170505f3 379 Pfam PF07687 Peptidase dimerisation domain 177 284 2.2E-26 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CVS48_RS07990 f889037c01355c80f66009ee2815f594 330 PIRSF PIRSF017082 1 330 2.1E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS07990 f889037c01355c80f66009ee2815f594 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 326 5.1E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS07990 f889037c01355c80f66009ee2815f594 330 SUPERFAMILY SSF53850 119 290 1.9E-11 T 29-03-2018 CVS48_RS07990 f889037c01355c80f66009ee2815f594 330 Gene3D G3DSA:3.40.190.10 129 240 9.6E-13 T 29-03-2018 CVS48_RS12690 3119735a1478f8ad1aac03ef1254d233 122 Pfam PF03640 Secreted repeat of unknown function 25 66 1.1E-14 T 29-03-2018 IPR005297 Lipoprotein repeat CVS48_RS12690 3119735a1478f8ad1aac03ef1254d233 122 Pfam PF03640 Secreted repeat of unknown function 78 121 4.3E-20 T 29-03-2018 IPR005297 Lipoprotein repeat CVS48_RS12690 3119735a1478f8ad1aac03ef1254d233 122 PIRSF PIRSF029720 1 122 4.6E-48 T 29-03-2018 IPR014558 Uncharacterised conserved lipoprotein CVS48_RS09680 84e3537103d0b13d4f83a17ccfa7130b 152 SUPERFAMILY SSF46785 10 148 2.25E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09680 84e3537103d0b13d4f83a17ccfa7130b 152 Gene3D G3DSA:1.10.10.10 2 148 5.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09680 84e3537103d0b13d4f83a17ccfa7130b 152 SMART SM00347 35 135 8.2E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS09680 84e3537103d0b13d4f83a17ccfa7130b 152 Pfam PF01047 MarR family 42 100 6.1E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 PIRSF PIRSF015855 3 484 3.4E-99 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 Gene3D G3DSA:3.40.50.150 38 443 6.0E-53 T 29-03-2018 CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 SUPERFAMILY SSF53335 334 433 6.18E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 SUPERFAMILY SSF53335 38 218 6.18E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 64 70 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 116 135 1.2E-14 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 358 380 1.2E-14 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 61 73 1.2E-14 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 381 395 1.2E-14 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CVS48_RS21480 ca374723ae0ee0e332fe2ed6060c94df 585 Pfam PF01555 DNA methylase 61 418 3.7E-33 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CVS48_RS17900 9307ff7e5cd552a2662bc4631c887159 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 269 3.3E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS17900 9307ff7e5cd552a2662bc4631c887159 272 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 59 161 2.0E-19 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS17900 9307ff7e5cd552a2662bc4631c887159 272 Gene3D G3DSA:1.10.3720.10 55 272 6.6E-33 T 29-03-2018 CVS48_RS17900 9307ff7e5cd552a2662bc4631c887159 272 SUPERFAMILY SSF161098 59 255 6.93E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS17400 e06abb797ac0349f9dbcff2cd8e2a55d 482 SUPERFAMILY SSF89796 225 475 9.81E-55 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS17400 e06abb797ac0349f9dbcff2cd8e2a55d 482 SUPERFAMILY SSF89796 42 220 2.35E-27 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS17400 e06abb797ac0349f9dbcff2cd8e2a55d 482 Gene3D G3DSA:3.30.1540.10 110 204 8.0E-15 T 29-03-2018 CVS48_RS17400 e06abb797ac0349f9dbcff2cd8e2a55d 482 Gene3D G3DSA:3.40.50.10540 221 440 1.3E-68 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS17400 e06abb797ac0349f9dbcff2cd8e2a55d 482 Pfam PF02515 CoA-transferase family III 227 431 2.5E-45 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS27250 64794973c85b8869d8b8f0e9e1d11400 282 SUPERFAMILY SSF140959 25 282 7.72E-103 T 29-03-2018 CVS48_RS27250 64794973c85b8869d8b8f0e9e1d11400 282 Pfam PF03301 Tryptophan 2,3-dioxygenase 14 207 3.9E-41 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CVS48_RS27250 64794973c85b8869d8b8f0e9e1d11400 282 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 19 282 1.6E-133 T 29-03-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 CVS48_RS27250 64794973c85b8869d8b8f0e9e1d11400 282 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 19 282 41.246 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CVS48_RS21605 6d2ad11fb7044c4b81bd32e80dd13b66 553 SUPERFAMILY SSF52540 141 385 1.6E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21605 6d2ad11fb7044c4b81bd32e80dd13b66 553 Pfam PF05621 Bacterial TniB protein 140 375 9.9E-16 T 29-03-2018 IPR008868 Bacterial TniB CVS48_RS21605 6d2ad11fb7044c4b81bd32e80dd13b66 553 Gene3D G3DSA:1.10.8.10 443 490 0.0012 T 29-03-2018 CVS48_RS21605 6d2ad11fb7044c4b81bd32e80dd13b66 553 Gene3D G3DSA:3.40.50.300 83 296 1.6E-6 T 29-03-2018 CVS48_RS00950 b59c794265816c576dbae7887dd55ab9 263 TIGRFAM TIGR03761 ICE_PFL4669: integrating conjugative element protein, PFL_4669 family 13 225 1.1E-88 T 29-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 CVS48_RS00950 b59c794265816c576dbae7887dd55ab9 263 Pfam PF08900 Domain of unknown function (DUF1845) 12 222 2.1E-79 T 29-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 CVS48_RS17720 3b5a9fb8f4596de00e90a3b2b712cc10 431 SUPERFAMILY SSF53383 9 429 5.32E-131 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS17720 3b5a9fb8f4596de00e90a3b2b712cc10 431 Gene3D G3DSA:3.40.640.10 9 295 1.1E-60 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS17720 3b5a9fb8f4596de00e90a3b2b712cc10 431 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 11 429 1.5E-197 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CVS48_RS17720 3b5a9fb8f4596de00e90a3b2b712cc10 431 PIRSF PIRSF001434 1 431 4.1E-129 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS17720 3b5a9fb8f4596de00e90a3b2b712cc10 431 Gene3D G3DSA:3.90.1150.10 297 431 4.8E-50 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS17720 3b5a9fb8f4596de00e90a3b2b712cc10 431 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 428 1.1E-141 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS17720 3b5a9fb8f4596de00e90a3b2b712cc10 431 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 204 218 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CVS48_RS10055 20db1d17b86226b85853a2a25679d654 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.7E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS10055 20db1d17b86226b85853a2a25679d654 295 SUPERFAMILY SSF53850 92 291 1.21E-39 T 29-03-2018 CVS48_RS10055 20db1d17b86226b85853a2a25679d654 295 Gene3D G3DSA:3.40.190.10 95 182 9.5E-13 T 29-03-2018 CVS48_RS10055 20db1d17b86226b85853a2a25679d654 295 Gene3D G3DSA:1.10.10.10 4 94 9.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10055 20db1d17b86226b85853a2a25679d654 295 Pfam PF03466 LysR substrate binding domain 94 293 1.2E-25 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS10055 20db1d17b86226b85853a2a25679d654 295 Gene3D G3DSA:3.40.190.10 183 266 6.2E-21 T 29-03-2018 CVS48_RS10055 20db1d17b86226b85853a2a25679d654 295 SUPERFAMILY SSF46785 3 83 1.09E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27570 a1d476b9e25bc8be3f07b04c5c525990 564 Pfam PF13632 Glycosyl transferase family group 2 167 386 2.3E-48 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS27570 a1d476b9e25bc8be3f07b04c5c525990 564 Gene3D G3DSA:3.90.550.10 37 363 6.8E-11 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS27570 a1d476b9e25bc8be3f07b04c5c525990 564 SUPERFAMILY SSF160246 490 547 5.49E-10 T 29-03-2018 CVS48_RS27570 a1d476b9e25bc8be3f07b04c5c525990 564 SUPERFAMILY SSF53448 73 299 2.14E-11 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS27570 a1d476b9e25bc8be3f07b04c5c525990 564 SUPERFAMILY SSF53448 326 401 2.14E-11 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS27795 f869ebb15534fe40ddea82fa4b5ff3b1 363 SUPERFAMILY SSF52540 45 187 6.61E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27795 f869ebb15534fe40ddea82fa4b5ff3b1 363 Pfam PF03969 AFG1-like ATPase 3 355 3.6E-129 T 29-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 CVS48_RS27795 f869ebb15534fe40ddea82fa4b5ff3b1 363 Gene3D G3DSA:3.40.50.300 18 236 5.7E-15 T 29-03-2018 CVS48_RS21325 5c50e8bc33597d6d0a365dfce0be8b3c 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 2.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS21325 5c50e8bc33597d6d0a365dfce0be8b3c 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 2.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS21325 5c50e8bc33597d6d0a365dfce0be8b3c 313 Gene3D G3DSA:3.40.50.1820 9 312 5.1E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21325 5c50e8bc33597d6d0a365dfce0be8b3c 313 SUPERFAMILY SSF53474 24 301 1.41E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21325 5c50e8bc33597d6d0a365dfce0be8b3c 313 Pfam PF12697 Alpha/beta hydrolase family 40 308 3.6E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS04920 5fc6128bf2ea3ba81a9585d7133930d0 75 Pfam PF12512 Protein of unknown function (DUF3717) 3 68 1.9E-27 T 29-03-2018 IPR022191 Protein of unknown function DUF3717 CVS48_RS17590 2a6280fe6305a733c6a20cf74d67efe2 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 8.0E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17590 2a6280fe6305a733c6a20cf74d67efe2 328 Gene3D G3DSA:3.40.190.10 126 235 2.1E-8 T 29-03-2018 CVS48_RS17590 2a6280fe6305a733c6a20cf74d67efe2 328 SUPERFAMILY SSF53850 82 284 5.74E-11 T 29-03-2018 CVS48_RS17590 2a6280fe6305a733c6a20cf74d67efe2 328 PIRSF PIRSF017082 1 326 8.2E-74 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS20250 b551135bbbc70e6a836bd8a39e84cbc8 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CVS48_RS20250 b551135bbbc70e6a836bd8a39e84cbc8 400 Gene3D G3DSA:3.90.1150.10 277 400 9.5E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS20250 b551135bbbc70e6a836bd8a39e84cbc8 400 SUPERFAMILY SSF53383 1 398 2.04E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS20250 b551135bbbc70e6a836bd8a39e84cbc8 400 Gene3D G3DSA:3.40.640.10 40 276 1.8E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS20250 b551135bbbc70e6a836bd8a39e84cbc8 400 Pfam PF00155 Aminotransferase class I and II 32 390 4.4E-67 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS01500 6233fd6b714a24d9dec5735a47e42cb0 177 Gene3D G3DSA:3.40.50.850 1 177 3.5E-41 T 29-03-2018 CVS48_RS01500 6233fd6b714a24d9dec5735a47e42cb0 177 SUPERFAMILY SSF52499 1 177 1.22E-46 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS01500 6233fd6b714a24d9dec5735a47e42cb0 177 Pfam PF00857 Isochorismatase family 8 154 1.7E-29 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS22525 7c3fae7cd6df07a5a42a725fbaf6f17f 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 326 4.8E-90 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22525 7c3fae7cd6df07a5a42a725fbaf6f17f 333 SUPERFAMILY SSF53850 117 294 5.43E-12 T 29-03-2018 CVS48_RS22525 7c3fae7cd6df07a5a42a725fbaf6f17f 333 Gene3D G3DSA:3.40.190.10 136 302 1.1E-12 T 29-03-2018 CVS48_RS22525 7c3fae7cd6df07a5a42a725fbaf6f17f 333 PIRSF PIRSF017082 1 333 1.6E-79 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Pfam PF05650 Domain of unknown function (DUF802) 666 718 4.0E-12 T 29-03-2018 IPR008520 Domain of unknown function DUF802 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Pfam PF05650 Domain of unknown function (DUF802) 349 401 6.0E-19 T 29-03-2018 IPR008520 Domain of unknown function DUF802 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Pfam PF05650 Domain of unknown function (DUF802) 535 587 7.3E-16 T 29-03-2018 IPR008520 Domain of unknown function DUF802 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Pfam PF05650 Domain of unknown function (DUF802) 404 456 1.9E-15 T 29-03-2018 IPR008520 Domain of unknown function DUF802 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Pfam PF05650 Domain of unknown function (DUF802) 797 849 2.5E-12 T 29-03-2018 IPR008520 Domain of unknown function DUF802 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 SUPERFAMILY SSF58113 795 933 1.44E-5 T 29-03-2018 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Gene3D G3DSA:1.20.120.290 791 882 4.4E-20 T 29-03-2018 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Gene3D G3DSA:1.20.120.290 883 962 0.52 T 29-03-2018 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Gene3D G3DSA:1.20.120.290 530 619 4.9E-24 T 29-03-2018 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Gene3D G3DSA:1.20.120.290 620 659 0.11 T 29-03-2018 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Gene3D G3DSA:1.20.120.290 486 529 7.8E-5 T 29-03-2018 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Gene3D G3DSA:1.20.120.290 409 485 1.3E-20 T 29-03-2018 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Gene3D G3DSA:1.20.120.290 342 408 1.5E-15 T 29-03-2018 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Gene3D G3DSA:1.20.120.290 660 756 2.6E-20 T 29-03-2018 CVS48_RS20540 90347ccaa433867b0294803a04b98239 1097 Gene3D G3DSA:1.20.120.20 73 341 0.033 T 29-03-2018 CVS48_RS00670 53be84f6ca5fdc9689f0435f9206a13b 472 TIGRFAM TIGR03752 conj_TIGR03752: integrating conjugative element protein, PFL_4705 family 2 462 5.6E-187 T 29-03-2018 IPR021207 Integrating conjugative element protein, PFL4705 CVS48_RS00670 53be84f6ca5fdc9689f0435f9206a13b 472 Gene3D G3DSA:1.20.1170.10 42 403 2.5E-8 T 29-03-2018 CVS48_RS06080 720d7b883643ce23e56752f897439dfe 307 Gene3D G3DSA:1.10.3720.10 19 295 4.8E-43 T 29-03-2018 CVS48_RS06080 720d7b883643ce23e56752f897439dfe 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 304 7.4E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS06080 720d7b883643ce23e56752f897439dfe 307 SUPERFAMILY SSF161098 99 289 1.1E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS06080 720d7b883643ce23e56752f897439dfe 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 19 64 3.2E-11 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 SUPERFAMILY SSF51126 469 493 2.86E-32 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 SUPERFAMILY SSF51126 172 420 2.86E-32 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 Pfam PF12545 Filamentous haemagglutinin family outer membrane protein 4020 4130 1.1E-38 T 29-03-2018 IPR021026 Filamentous haemagglutinin family outer membrane protein, domain of unknown function DUF3739 CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 183 258 2.6E-19 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 Pfam PF05860 haemagglutination activity domain 162 261 9.7E-20 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 Gene3D G3DSA:2.160.20.10 1459 1713 0.024 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 Gene3D G3DSA:2.160.20.10 2294 2486 1.7E-6 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 Gene3D G3DSA:2.160.20.10 153 424 2.6E-34 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 Gene3D G3DSA:2.160.20.10 766 1011 2.7E-8 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 Gene3D G3DSA:2.160.20.10 1027 1304 0.016 T 29-03-2018 IPR012334 Pectin lyase fold CVS48_RS25475 cdd42bcdc3b956f8d320633f5d7d2713 4235 SMART SM00912 158 262 2.5E-24 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CVS48_RS24105 ed1a3b5bed06f2333fa26d83885c8632 281 SUPERFAMILY SSF82689 173 269 2.48E-22 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CVS48_RS24105 ed1a3b5bed06f2333fa26d83885c8632 281 Gene3D G3DSA:3.30.70.100 173 265 8.0E-20 T 29-03-2018 CVS48_RS24105 ed1a3b5bed06f2333fa26d83885c8632 281 SUPERFAMILY SSF50182 106 172 7.52E-15 T 29-03-2018 IPR010920 LSM domain CVS48_RS24105 ed1a3b5bed06f2333fa26d83885c8632 281 Pfam PF05552 Conserved TM helix 10 50 6.3E-7 T 29-03-2018 IPR008910 Conserved TM helix CVS48_RS24105 ed1a3b5bed06f2333fa26d83885c8632 281 Gene3D G3DSA:2.30.30.60 123 172 1.3E-10 T 29-03-2018 CVS48_RS24105 ed1a3b5bed06f2333fa26d83885c8632 281 SUPERFAMILY SSF82861 19 104 3.53E-18 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CVS48_RS24105 ed1a3b5bed06f2333fa26d83885c8632 281 Pfam PF00924 Mechanosensitive ion channel 69 258 1.4E-45 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CVS48_RS12795 d4661efff1e1b18c96375e788bed5cd8 230 Pfam PF07077 Protein of unknown function (DUF1345) 53 221 2.1E-55 T 29-03-2018 IPR009781 Protein of unknown function DUF1345 CVS48_RS13500 4bedadd8596a5f746558e0bca359d614 356 Gene3D G3DSA:1.10.3470.10 6 303 4.4E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS13500 4bedadd8596a5f746558e0bca359d614 356 Pfam PF02653 Branched-chain amino acid transport system / permease component 26 280 1.6E-37 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS17550 0db0ea621de4f161e0b0ba0ac3b2763f 263 Pfam PF00174 Oxidoreductase molybdopterin binding domain 109 252 1.0E-32 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CVS48_RS17550 0db0ea621de4f161e0b0ba0ac3b2763f 263 Gene3D G3DSA:3.90.420.10 58 263 2.8E-56 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CVS48_RS17550 0db0ea621de4f161e0b0ba0ac3b2763f 263 SUPERFAMILY SSF56524 59 262 2.49E-64 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CVS48_RS13075 010b757999ffbfa816efa1d560f1b44c 137 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 10 118 1.4E-17 T 29-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CVS48_RS15780 ffb54aa37625da1bb78e88af67712769 320 Gene3D G3DSA:1.10.1040.10 189 293 7.7E-22 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS15780 ffb54aa37625da1bb78e88af67712769 320 PIRSF PIRSF000105 9 312 2.7E-69 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CVS48_RS15780 ffb54aa37625da1bb78e88af67712769 320 Gene3D G3DSA:3.40.50.720 2 187 4.9E-39 T 29-03-2018 CVS48_RS15780 ffb54aa37625da1bb78e88af67712769 320 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 17 185 1.8E-39 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS15780 ffb54aa37625da1bb78e88af67712769 320 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 187 211 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS15780 ffb54aa37625da1bb78e88af67712769 320 SUPERFAMILY SSF51735 15 185 1.43E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS15780 ffb54aa37625da1bb78e88af67712769 320 SUPERFAMILY SSF48179 189 293 5.87E-22 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS15780 ffb54aa37625da1bb78e88af67712769 320 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 288 1.3E-17 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CVS48_RS18995 0bea1e3b95bb884e55dc98b72d9feeee 715 Pfam PF12805 FUSC-like inner membrane protein yccS 68 191 4.6E-7 T 29-03-2018 IPR032692 Integral membrane protein YccS, N-terminal CVS48_RS18995 0bea1e3b95bb884e55dc98b72d9feeee 715 Pfam PF13515 Fusaric acid resistance protein-like 409 534 6.0E-17 T 29-03-2018 CVS48_RS15030 4e9eb3adc3b5a9eaa12f0f2f9922a7b5 132 Pfam PF04304 Protein of unknown function (DUF454) 3 117 1.0E-36 T 29-03-2018 IPR007401 Protein of unknown function DUF454 CVS48_RS15030 4e9eb3adc3b5a9eaa12f0f2f9922a7b5 132 PIRSF PIRSF016789 2 123 8.5E-37 T 29-03-2018 IPR007401 Protein of unknown function DUF454 CVS48_RS05945 9a8d2dd619548de0b72a4919661f970d 362 Gene3D G3DSA:2.40.50.140 286 338 0.0076 T 29-03-2018 CVS48_RS05945 9a8d2dd619548de0b72a4919661f970d 362 SUPERFAMILY SSF52540 4 242 2.05E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05945 9a8d2dd619548de0b72a4919661f970d 362 Pfam PF08402 TOBE domain 275 347 4.8E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS05945 9a8d2dd619548de0b72a4919661f970d 362 SMART SM00382 28 211 3.7E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05945 9a8d2dd619548de0b72a4919661f970d 362 SUPERFAMILY SSF50331 238 344 5.1E-11 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS05945 9a8d2dd619548de0b72a4919661f970d 362 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05945 9a8d2dd619548de0b72a4919661f970d 362 Pfam PF00005 ABC transporter 20 161 2.6E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05945 9a8d2dd619548de0b72a4919661f970d 362 Gene3D G3DSA:2.40.50.100 248 285 0.0012 T 29-03-2018 CVS48_RS05945 9a8d2dd619548de0b72a4919661f970d 362 Gene3D G3DSA:3.40.50.300 1 247 2.6E-74 T 29-03-2018 CVS48_RS04560 fc1497118c428eca991f2e9e960695a1 493 Pfam PF13437 HlyD family secretion protein 355 454 1.1E-12 T 29-03-2018 CVS48_RS04560 fc1497118c428eca991f2e9e960695a1 493 Gene3D G3DSA:2.40.50.100 43 391 8.4E-8 T 29-03-2018 CVS48_RS04560 fc1497118c428eca991f2e9e960695a1 493 SUPERFAMILY SSF111369 258 422 8.5E-8 T 29-03-2018 CVS48_RS17965 3914360f0320f6832ff09c6ed6581617 297 Gene3D G3DSA:1.10.10.10 1 86 1.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17965 3914360f0320f6832ff09c6ed6581617 297 Pfam PF03466 LysR substrate binding domain 90 290 6.9E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS17965 3914360f0320f6832ff09c6ed6581617 297 Gene3D G3DSA:3.40.190.10 183 266 1.7E-17 T 29-03-2018 CVS48_RS17965 3914360f0320f6832ff09c6ed6581617 297 Gene3D G3DSA:3.40.190.10 91 182 4.6E-20 T 29-03-2018 CVS48_RS17965 3914360f0320f6832ff09c6ed6581617 297 SUPERFAMILY SSF46785 4 113 1.73E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS17965 3914360f0320f6832ff09c6ed6581617 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS17965 3914360f0320f6832ff09c6ed6581617 297 SUPERFAMILY SSF53850 90 293 8.45E-37 T 29-03-2018 CVS48_RS09150 cbfee875cecab023712c5bc77357bd8a 445 Pfam PF11299 Protein of unknown function (DUF3100) 30 270 2.7E-88 T 29-03-2018 IPR021450 Protein of unknown function DUF3100 CVS48_RS18140 c27bb302b183a44a39e10a3fb7b88009 349 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 73 336 6.1E-60 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CVS48_RS18140 c27bb302b183a44a39e10a3fb7b88009 349 Gene3D G3DSA:2.120.10.30 39 99 0.035 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS18140 c27bb302b183a44a39e10a3fb7b88009 349 Gene3D G3DSA:2.120.10.30 100 348 4.3E-35 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS18140 c27bb302b183a44a39e10a3fb7b88009 349 SUPERFAMILY SSF63829 34 347 8.94E-73 T 29-03-2018 CVS48_RS23485 1fc86b451df34ce0d537d18729545ed9 112 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 15 104 1.7E-24 T 29-03-2018 IPR009241 Toxin HigB-like CVS48_RS19545 358629f0abc41e20cff37062e2a3494a 699 Pfam PF00593 TonB dependent receptor 252 696 6.9E-40 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS19545 358629f0abc41e20cff37062e2a3494a 699 SUPERFAMILY SSF56935 52 699 8.79E-92 T 29-03-2018 CVS48_RS19545 358629f0abc41e20cff37062e2a3494a 699 Gene3D G3DSA:2.40.170.20 168 699 2.8E-52 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS19545 358629f0abc41e20cff37062e2a3494a 699 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 166 4.6E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS19545 358629f0abc41e20cff37062e2a3494a 699 Gene3D G3DSA:2.170.130.10 41 167 5.7E-19 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS07200 e60e74857da80b6a19f76b39eb4d09a1 307 SUPERFAMILY SSF56752 30 300 3.01E-73 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CVS48_RS07200 e60e74857da80b6a19f76b39eb4d09a1 307 Pfam PF01063 Amino-transferase class IV 56 278 7.1E-42 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CVS48_RS07200 e60e74857da80b6a19f76b39eb4d09a1 307 Gene3D G3DSA:3.20.10.10 159 306 2.5E-33 T 29-03-2018 CVS48_RS07200 e60e74857da80b6a19f76b39eb4d09a1 307 Gene3D G3DSA:3.30.470.10 24 158 1.0E-32 T 29-03-2018 CVS48_RS00530 4d4de84fc27c7d14dcd424a133416d1a 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 8.7E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS00530 4d4de84fc27c7d14dcd424a133416d1a 230 SUPERFAMILY SSF52172 1 118 3.98E-39 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS00530 4d4de84fc27c7d14dcd424a133416d1a 230 SMART SM00862 146 221 5.2E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS00530 4d4de84fc27c7d14dcd424a133416d1a 230 SUPERFAMILY SSF46894 122 222 7.94E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS00530 4d4de84fc27c7d14dcd424a133416d1a 230 Gene3D G3DSA:3.40.50.2300 1 121 3.2E-32 T 29-03-2018 CVS48_RS00530 4d4de84fc27c7d14dcd424a133416d1a 230 Pfam PF00072 Response regulator receiver domain 4 113 4.2E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS00530 4d4de84fc27c7d14dcd424a133416d1a 230 Gene3D G3DSA:1.10.10.10 122 227 5.4E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00530 4d4de84fc27c7d14dcd424a133416d1a 230 SMART SM00448 1 112 1.6E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS00530 4d4de84fc27c7d14dcd424a133416d1a 230 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 221 2.7E-103 T 29-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 CVS48_RS08390 7eed9a72462ba6541800a877f4a26a52 585 Pfam PF07655 Secretin N-terminal domain 205 294 1.1E-7 T 29-03-2018 IPR011514 Secretin, N-terminal GO:0009297|GO:0019867 CVS48_RS08390 7eed9a72462ba6541800a877f4a26a52 585 TIGRFAM TIGR02520 pilus_B_mal_scr: type IVB pilus formation outer membrane protein, R64 PilN family 56 563 9.5E-157 T 29-03-2018 IPR013359 Pilus formation type IVB, outer membrane PilN CVS48_RS08390 7eed9a72462ba6541800a877f4a26a52 585 Pfam PF00263 Bacterial type II and III secretion system protein 397 534 2.4E-13 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CVS48_RS21635 824d6659dadb3466b4b2d60f7f1f6f67 593 Pfam PF03235 Protein of unknown function DUF262 11 218 7.5E-33 T 29-03-2018 IPR004919 Domain of unknown function DUF262 CVS48_RS21635 824d6659dadb3466b4b2d60f7f1f6f67 593 Pfam PF07510 Protein of unknown function (DUF1524) 439 585 3.2E-20 T 29-03-2018 IPR011089 Domain of unknown function DUF1524 CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 SUPERFAMILY SSF51735 1 230 5.86E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 Pfam PF00106 short chain dehydrogenase 6 193 1.0E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 8.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 8.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 8.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 8.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 Gene3D G3DSA:3.40.50.720 1 254 2.7E-51 T 29-03-2018 CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 5.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS20865 f948962d26c600bd0c448c1db7bf308d 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS23025 5440ffbc9409bc14a14db3de4b0d0c27 431 SUPERFAMILY SSF56601 61 428 1.48E-81 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS23025 5440ffbc9409bc14a14db3de4b0d0c27 431 Pfam PF00144 Beta-lactamase 61 429 9.2E-64 T 29-03-2018 IPR001466 Beta-lactamase-related CVS48_RS23025 5440ffbc9409bc14a14db3de4b0d0c27 431 ProSitePatterns PS00336 Beta-lactamase class-C active site. 109 116 - T 29-03-2018 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 CVS48_RS23025 5440ffbc9409bc14a14db3de4b0d0c27 431 Gene3D G3DSA:3.40.710.10 59 429 7.3E-59 T 29-03-2018 CVS48_RS20145 30f1f20b6202e747646d675f33e1c315 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 1.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20145 30f1f20b6202e747646d675f33e1c315 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 1.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20145 30f1f20b6202e747646d675f33e1c315 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 1.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20145 30f1f20b6202e747646d675f33e1c315 161 SMART SM00347 29 130 5.4E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS20145 30f1f20b6202e747646d675f33e1c315 161 SUPERFAMILY SSF46785 8 144 9.23E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS20145 30f1f20b6202e747646d675f33e1c315 161 Pfam PF12802 MarR family 35 94 1.3E-10 T 29-03-2018 CVS48_RS20145 30f1f20b6202e747646d675f33e1c315 161 Gene3D G3DSA:1.10.10.10 5 161 4.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12565 9aef561b63d948d42c45341b92113451 348 SUPERFAMILY SSF144064 14 341 8.14E-122 T 29-03-2018 CVS48_RS12565 9aef561b63d948d42c45341b92113451 348 Gene3D G3DSA:3.40.1570.10 175 344 5.0E-54 T 29-03-2018 CVS48_RS12565 9aef561b63d948d42c45341b92113451 348 Gene3D G3DSA:3.40.1570.10 13 174 3.0E-47 T 29-03-2018 CVS48_RS12565 9aef561b63d948d42c45341b92113451 348 Pfam PF05171 Haemin-degrading HemS.ChuX domain 209 338 1.6E-43 T 29-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 CVS48_RS12565 9aef561b63d948d42c45341b92113451 348 Pfam PF05171 Haemin-degrading HemS.ChuX domain 37 161 5.2E-37 T 29-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 CVS48_RS25130 a5d9dcd615b048acd570a468d0abe01b 223 Gene3D G3DSA:3.30.70.100 107 180 0.011 T 29-03-2018 CVS48_RS25130 a5d9dcd615b048acd570a468d0abe01b 223 Gene3D G3DSA:3.30.70.100 7 102 1.1E-6 T 29-03-2018 CVS48_RS03925 9aafcc6cd9f78dcdced15f0b79db0b08 397 Pfam PF13458 Periplasmic binding protein 32 368 1.0E-65 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS03925 9aafcc6cd9f78dcdced15f0b79db0b08 397 Gene3D G3DSA:3.40.50.2300 155 314 1.2E-31 T 29-03-2018 CVS48_RS03925 9aafcc6cd9f78dcdced15f0b79db0b08 397 SUPERFAMILY SSF53822 32 376 6.6E-78 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS03925 9aafcc6cd9f78dcdced15f0b79db0b08 397 Gene3D G3DSA:3.40.50.2300 33 154 5.4E-20 T 29-03-2018 CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 SUPERFAMILY SSF49584 130 235 4.58E-10 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 17 136 3.3E-36 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 Gene3D G3DSA:2.60.40.10 16 137 4.6E-32 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 161 231 9.1E-6 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 PRINTS PR00969 Pili chaperone signature 17 26 4.7E-26 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 PRINTS PR00969 Pili chaperone signature 66 87 4.7E-26 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 PRINTS PR00969 Pili chaperone signature 94 111 4.7E-26 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 PRINTS PR00969 Pili chaperone signature 118 133 4.7E-26 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 PRINTS PR00969 Pili chaperone signature 155 170 4.7E-26 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 Gene3D G3DSA:2.60.40.10 139 244 1.3E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS24975 649ab29af85dd0bcbbae1f8f20a6b66c 244 SUPERFAMILY SSF49354 12 136 1.67E-37 T 29-03-2018 IPR008962 PapD-like CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 332 4.7E-30 T 29-03-2018 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 4.7E-30 T 29-03-2018 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 4.7E-30 T 29-03-2018 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 4.7E-30 T 29-03-2018 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 4.7E-30 T 29-03-2018 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 Gene3D G3DSA:3.30.9.10 174 288 9.1E-47 T 29-03-2018 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 Gene3D G3DSA:3.30.9.10 315 392 5.2E-19 T 29-03-2018 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 Gene3D G3DSA:3.50.50.60 3 173 3.9E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 SUPERFAMILY SSF54373 179 279 7.85E-38 T 29-03-2018 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 Pfam PF01494 FAD binding domain 2 346 3.3E-82 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 SUPERFAMILY SSF51905 278 394 3.11E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS25855 c4d37c5e7af89ce9ce0c8c820bf54eb2 399 SUPERFAMILY SSF51905 1 176 3.11E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS06395 8f39b4b97611f3c4589395c403dcb128 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 22.019 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CVS48_RS06395 8f39b4b97611f3c4589395c403dcb128 98 SUPERFAMILY SSF54189 2 92 5.76E-30 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06395 8f39b4b97611f3c4589395c403dcb128 98 Gene3D G3DSA:3.30.70.330 5 98 4.2E-29 T 29-03-2018 CVS48_RS06395 8f39b4b97611f3c4589395c403dcb128 98 Pfam PF00276 Ribosomal protein L23 8 94 4.1E-30 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CVS48_RS02680 4a81d952875101d535404f2d6bb48be1 226 TIGRFAM TIGR02796 tolQ: protein TolQ 8 223 8.7E-84 T 29-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 CVS48_RS02680 4a81d952875101d535404f2d6bb48be1 226 Pfam PF01618 MotA/TolQ/ExbB proton channel family 80 211 4.8E-42 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CVS48_RS19030 3f6b3e17152ad33685b4a2dd827c8dac 113 Pfam PF05957 Bacterial protein of unknown function (DUF883) 34 112 2.5E-17 T 29-03-2018 IPR010279 Protein of unknown function DUF883, ElaB CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 406 1.4E-197 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 SMART SM00825 Beta-ketoacyl synthase 5 409 5.6E-15 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 PIRSF PIRSF000447 1 409 1.1E-183 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 SUPERFAMILY SSF53901 2 251 1.15E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 246 2.3E-64 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 Gene3D G3DSA:3.40.47.10 260 409 7.2E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 366 4.1E-32 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 Gene3D G3DSA:3.40.47.10 5 259 1.5E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS28305 0d0e4fabea395c06796e8f398d12a52e 409 SUPERFAMILY SSF53901 213 408 1.05E-67 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CVS48_RS09055 63a4327e11ed8e47de4ab1a42a54eef6 360 Pfam PF04443 Acyl-protein synthetase, LuxE 26 353 1.0E-16 T 29-03-2018 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 CVS48_RS09055 63a4327e11ed8e47de4ab1a42a54eef6 360 SUPERFAMILY SSF56801 139 338 5.23E-6 T 29-03-2018 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 338 493 3.2E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 SMART SM00086 80 121 0.005 T 29-03-2018 IPR001610 PAC motif CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 Gene3D G3DSA:3.40.50.10600 8 130 5.1E-29 T 29-03-2018 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 112 8.2E-16 T 29-03-2018 IPR000014 PAS domain CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 Gene3D G3DSA:1.10.287.950 334 530 1.7E-45 T 29-03-2018 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 Gene3D G3DSA:1.10.287.950 225 333 1.1E-12 T 29-03-2018 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 SMART SM00091 8 74 2.9E-4 T 29-03-2018 IPR000014 PAS domain CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 SMART SM00304 226 278 5.8E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 SMART SM00283 279 526 7.1E-81 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 377 404 3.9E-56 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 435 3.9E-56 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 300 329 3.9E-56 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 454 483 3.9E-56 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 SUPERFAMILY SSF55785 20 114 1.92E-28 T 29-03-2018 IPR000014 PAS domain CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 SUPERFAMILY SSF58104 246 527 4.32E-70 T 29-03-2018 CVS48_RS16935 6d5dcf281abb8c64a2c5cbaa7d8b9f3b 531 Pfam PF08447 PAS fold 30 112 2.3E-16 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CVS48_RS07750 be236159e1762f50543f1c705271fb44 112 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 1.2E-30 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CVS48_RS07750 be236159e1762f50543f1c705271fb44 112 Gene3D G3DSA:3.30.160.100 1 96 4.4E-29 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CVS48_RS07750 be236159e1762f50543f1c705271fb44 112 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 7.1E-25 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CVS48_RS07750 be236159e1762f50543f1c705271fb44 112 SUPERFAMILY SSF69754 2 101 4.97E-33 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CVS48_RS27925 8da701d943d72686dae299d6f30033cb 296 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 8 292 3.0E-126 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CVS48_RS27925 8da701d943d72686dae299d6f30033cb 296 ProSitePatterns PS00161 Isocitrate lyase signature. 122 127 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CVS48_RS27925 8da701d943d72686dae299d6f30033cb 296 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 255 2.8E-52 T 29-03-2018 CVS48_RS27925 8da701d943d72686dae299d6f30033cb 296 Gene3D G3DSA:3.20.20.60 5 296 1.4E-89 T 29-03-2018 CVS48_RS27925 8da701d943d72686dae299d6f30033cb 296 SUPERFAMILY SSF51621 4 291 6.28E-101 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS27925 8da701d943d72686dae299d6f30033cb 296 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 5 293 48.25 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CVS48_RS13265 d10ef5321d38b089c13f18ece9c40e43 170 SUPERFAMILY SSF55781 29 162 4.91E-10 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS13265 d10ef5321d38b089c13f18ece9c40e43 170 Gene3D G3DSA:3.30.450.40 12 170 8.7E-10 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS06845 4db74959745cde1d5c0990d9f825ff2b 102 Pfam PF13663 Domain of unknown function (DUF4148) 62 98 2.8E-10 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS06845 4db74959745cde1d5c0990d9f825ff2b 102 Pfam PF13663 Domain of unknown function (DUF4148) 1 57 2.4E-12 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS13815 0d27470cf183a6b204e03c0f5b159673 361 SUPERFAMILY SSF50331 239 359 1.81E-11 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CVS48_RS13815 0d27470cf183a6b204e03c0f5b159673 361 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13815 0d27470cf183a6b204e03c0f5b159673 361 Pfam PF08402 TOBE domain 281 359 3.0E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CVS48_RS13815 0d27470cf183a6b204e03c0f5b159673 361 SMART SM00382 30 213 1.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13815 0d27470cf183a6b204e03c0f5b159673 361 Gene3D G3DSA:3.40.50.300 1 251 1.5E-75 T 29-03-2018 CVS48_RS13815 0d27470cf183a6b204e03c0f5b159673 361 SUPERFAMILY SSF52540 6 245 1.5E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13815 0d27470cf183a6b204e03c0f5b159673 361 Pfam PF00005 ABC transporter 21 163 7.7E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS10960 e4891c6fdd039e25c1abb9f3dc632bd7 83 Gene3D G3DSA:3.30.70.20 2 83 1.1E-17 T 29-03-2018 CVS48_RS10960 e4891c6fdd039e25c1abb9f3dc632bd7 83 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CVS48_RS10960 e4891c6fdd039e25c1abb9f3dc632bd7 83 Pfam PF00037 4Fe-4S binding domain 5 25 3.4E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS10960 e4891c6fdd039e25c1abb9f3dc632bd7 83 SUPERFAMILY SSF54862 5 77 2.21E-20 T 29-03-2018 CVS48_RS13420 f96ff6873361014a73712033f38ebf6f 162 Pfam PF00731 AIR carboxylase 1 148 2.5E-57 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CVS48_RS13420 f96ff6873361014a73712033f38ebf6f 162 Gene3D G3DSA:3.40.50.7700 1 155 3.6E-59 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CVS48_RS13420 f96ff6873361014a73712033f38ebf6f 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 154 29.894 T 29-03-2018 IPR033747 Class I PurE CVS48_RS13420 f96ff6873361014a73712033f38ebf6f 162 SUPERFAMILY SSF52255 1 155 4.06E-59 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CVS48_RS13420 f96ff6873361014a73712033f38ebf6f 162 PIRSF PIRSF001338 1 158 7.6E-61 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CVS48_RS13420 f96ff6873361014a73712033f38ebf6f 162 SMART SM01001 1 150 4.4E-86 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CVS48_RS13420 f96ff6873361014a73712033f38ebf6f 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 152 3.5E-59 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CVS48_RS27085 9633536053565c4fac8225ffef3a70b0 288 SUPERFAMILY SSF52821 165 287 1.96E-31 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS27085 9633536053565c4fac8225ffef3a70b0 288 Gene3D G3DSA:3.40.250.10 163 288 7.1E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS27085 9633536053565c4fac8225ffef3a70b0 288 ProSitePatterns PS00380 Rhodanese signature 1. 44 55 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CVS48_RS27085 9633536053565c4fac8225ffef3a70b0 288 Gene3D G3DSA:3.40.250.10 2 153 2.8E-32 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS27085 9633536053565c4fac8225ffef3a70b0 288 SMART SM00450 162 282 2.2E-9 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS27085 9633536053565c4fac8225ffef3a70b0 288 SMART SM00450 7 137 1.6E-21 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS27085 9633536053565c4fac8225ffef3a70b0 288 Pfam PF00581 Rhodanese-like domain 8 133 1.0E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS27085 9633536053565c4fac8225ffef3a70b0 288 Pfam PF00581 Rhodanese-like domain 164 278 3.2E-7 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS27085 9633536053565c4fac8225ffef3a70b0 288 SUPERFAMILY SSF52821 2 144 3.93E-43 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS23345 743d0cd9be363675ec2de2663b47548b 415 Pfam PF01266 FAD dependent oxidoreductase 4 396 2.7E-55 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS23345 743d0cd9be363675ec2de2663b47548b 415 SUPERFAMILY SSF51905 3 55 3.5E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23345 743d0cd9be363675ec2de2663b47548b 415 SUPERFAMILY SSF51905 357 414 3.5E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23345 743d0cd9be363675ec2de2663b47548b 415 SUPERFAMILY SSF51905 116 269 3.5E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23345 743d0cd9be363675ec2de2663b47548b 415 Gene3D G3DSA:3.50.50.60 1 415 8.9E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23345 743d0cd9be363675ec2de2663b47548b 415 SUPERFAMILY SSF54373 272 357 8.24E-6 T 29-03-2018 CVS48_RS10170 6eaefc78969f7a160ceec4035d2b587d 327 SUPERFAMILY SSF53850 112 284 1.54E-15 T 29-03-2018 CVS48_RS10170 6eaefc78969f7a160ceec4035d2b587d 327 Gene3D G3DSA:3.40.190.10 125 235 5.0E-16 T 29-03-2018 CVS48_RS10170 6eaefc78969f7a160ceec4035d2b587d 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 313 5.5E-65 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS10170 6eaefc78969f7a160ceec4035d2b587d 327 PIRSF PIRSF017082 1 324 9.2E-69 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS18625 36969f6e39be2e205490e401c74c8685 271 SUPERFAMILY SSF52540 23 255 1.13E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18625 36969f6e39be2e205490e401c74c8685 271 Gene3D G3DSA:3.40.50.300 2 271 3.2E-72 T 29-03-2018 CVS48_RS18625 36969f6e39be2e205490e401c74c8685 271 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS18625 36969f6e39be2e205490e401c74c8685 271 SMART SM00382 41 233 8.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS18625 36969f6e39be2e205490e401c74c8685 271 Pfam PF00005 ABC transporter 33 183 2.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS22930 a322bb00fe59662305dda192c73068a8 329 SUPERFAMILY SSF53850 118 289 1.21E-12 T 29-03-2018 CVS48_RS22930 a322bb00fe59662305dda192c73068a8 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 326 1.3E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22930 a322bb00fe59662305dda192c73068a8 329 PIRSF PIRSF017082 1 328 4.0E-71 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22930 a322bb00fe59662305dda192c73068a8 329 Gene3D G3DSA:3.40.190.10 133 301 1.1E-9 T 29-03-2018 CVS48_RS01760 a1e7437bd1acd8e1a26642694e37bea6 370 SUPERFAMILY SSF89796 9 368 2.62E-125 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS01760 a1e7437bd1acd8e1a26642694e37bea6 370 Gene3D G3DSA:3.40.50.10540 5 370 7.4E-135 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS01760 a1e7437bd1acd8e1a26642694e37bea6 370 Pfam PF02515 CoA-transferase family III 11 368 9.0E-121 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS05030 b1d07e0c56422c221638222362a5f066 290 Gene3D G3DSA:3.40.190.10 169 264 1.8E-17 T 29-03-2018 CVS48_RS05030 b1d07e0c56422c221638222362a5f066 290 SUPERFAMILY SSF53850 90 288 2.02E-38 T 29-03-2018 CVS48_RS05030 b1d07e0c56422c221638222362a5f066 290 Gene3D G3DSA:1.10.10.10 1 87 3.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05030 b1d07e0c56422c221638222362a5f066 290 SUPERFAMILY SSF46785 4 112 9.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05030 b1d07e0c56422c221638222362a5f066 290 Pfam PF03466 LysR substrate binding domain 88 286 5.8E-40 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS05030 b1d07e0c56422c221638222362a5f066 290 Gene3D G3DSA:3.40.190.10 88 168 1.8E-19 T 29-03-2018 CVS48_RS05030 b1d07e0c56422c221638222362a5f066 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 9.2E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS18020 7090c413fcf261228c5936aea7442d1c 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS18020 7090c413fcf261228c5936aea7442d1c 250 SMART SM00382 26 223 7.4E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS18020 7090c413fcf261228c5936aea7442d1c 250 Gene3D G3DSA:3.40.50.300 1 249 2.4E-72 T 29-03-2018 CVS48_RS18020 7090c413fcf261228c5936aea7442d1c 250 PIRSF PIRSF039085 1 250 1.7E-119 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS18020 7090c413fcf261228c5936aea7442d1c 250 Pfam PF00005 ABC transporter 17 175 8.2E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS18020 7090c413fcf261228c5936aea7442d1c 250 SUPERFAMILY SSF52540 1 245 6.07E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16550 f38ea42406dda1c929e891a999ff40e2 202 SUPERFAMILY SSF52499 3 200 3.01E-43 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS16550 f38ea42406dda1c929e891a999ff40e2 202 Pfam PF00857 Isochorismatase family 9 194 4.9E-34 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CVS48_RS16550 f38ea42406dda1c929e891a999ff40e2 202 Gene3D G3DSA:3.40.50.850 1 202 8.1E-46 T 29-03-2018 CVS48_RS26005 09b8a5d6fe4bfa93081874455c35caaa 351 SUPERFAMILY SSF48019 220 348 2.89E-24 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CVS48_RS26005 09b8a5d6fe4bfa93081874455c35caaa 351 Gene3D G3DSA:3.40.50.300 2 148 1.7E-19 T 29-03-2018 CVS48_RS26005 09b8a5d6fe4bfa93081874455c35caaa 351 Gene3D G3DSA:1.10.8.60 151 230 2.4E-23 T 29-03-2018 CVS48_RS26005 09b8a5d6fe4bfa93081874455c35caaa 351 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 21 344 2.9E-75 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CVS48_RS26005 09b8a5d6fe4bfa93081874455c35caaa 351 Gene3D G3DSA:1.20.272.10 231 350 9.9E-22 T 29-03-2018 CVS48_RS26005 09b8a5d6fe4bfa93081874455c35caaa 351 Pfam PF06144 DNA polymerase III, delta subunit 25 197 2.7E-24 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CVS48_RS26005 09b8a5d6fe4bfa93081874455c35caaa 351 SUPERFAMILY SSF52540 9 218 1.01E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS26695 69da1cb8c3f9d00c635dbfeb7e8f423f 469 Gene3D G3DSA:3.40.50.1100 206 434 3.7E-85 T 29-03-2018 CVS48_RS26695 69da1cb8c3f9d00c635dbfeb7e8f423f 469 Pfam PF14821 Threonine synthase N terminus 2 79 1.8E-28 T 29-03-2018 IPR029144 Threonine synthase, N-terminal CVS48_RS26695 69da1cb8c3f9d00c635dbfeb7e8f423f 469 Gene3D G3DSA:3.40.50.1100 107 205 2.9E-13 T 29-03-2018 CVS48_RS26695 69da1cb8c3f9d00c635dbfeb7e8f423f 469 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 105 400 1.3E-11 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS26695 69da1cb8c3f9d00c635dbfeb7e8f423f 469 TIGRFAM TIGR00260 thrC: threonine synthase 80 428 2.1E-73 T 29-03-2018 IPR004450 Threonine synthase-like CVS48_RS26695 69da1cb8c3f9d00c635dbfeb7e8f423f 469 Gene3D G3DSA:3.90.1380.10 1 89 8.3E-32 T 29-03-2018 IPR029144 Threonine synthase, N-terminal CVS48_RS26695 69da1cb8c3f9d00c635dbfeb7e8f423f 469 SUPERFAMILY SSF53686 1 465 4.86E-152 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS08885 060187652d566d57d961f44aed5ff22a 99 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 3 55 1.6E-14 T 29-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ CVS48_RS08885 060187652d566d57d961f44aed5ff22a 99 Pfam PF04221 RelB antitoxin 4 51 9.0E-15 T 29-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ CVS48_RS24135 f8bd4ca0b69b523b069030c5256b15bd 271 SUPERFAMILY SSF53639 28 239 9.03E-60 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS24135 f8bd4ca0b69b523b069030c5256b15bd 271 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 35 218 5.8E-44 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS24135 f8bd4ca0b69b523b069030c5256b15bd 271 Gene3D G3DSA:3.40.225.10 19 271 2.6E-75 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS24135 f8bd4ca0b69b523b069030c5256b15bd 271 SMART SM01007 34 218 3.7E-59 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS12025 6572413cf0053817af5a6354d066afb8 231 Gene3D G3DSA:2.160.20.80 139 227 7.8E-20 T 29-03-2018 CVS48_RS12025 6572413cf0053817af5a6354d066afb8 231 Gene3D G3DSA:2.160.20.80 16 138 1.0E-22 T 29-03-2018 CVS48_RS12025 6572413cf0053817af5a6354d066afb8 231 Pfam PF00805 Pentapeptide repeats (8 copies) 33 68 5.4E-7 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS12025 6572413cf0053817af5a6354d066afb8 231 Pfam PF00805 Pentapeptide repeats (8 copies) 178 206 4.9E-7 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS12025 6572413cf0053817af5a6354d066afb8 231 SUPERFAMILY SSF141571 76 227 6.48E-33 T 29-03-2018 CVS48_RS12025 6572413cf0053817af5a6354d066afb8 231 Pfam PF13599 Pentapeptide repeats (9 copies) 91 168 1.3E-9 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS11065 19e780d3eb90bb1aeee58f9e3614281b 132 Gene3D G3DSA:1.10.3830.10 15 127 1.4E-38 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CVS48_RS11065 19e780d3eb90bb1aeee58f9e3614281b 132 Pfam PF01219 Prokaryotic diacylglycerol kinase 24 123 7.5E-34 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CVS48_RS09905 d6f2fcfed18b65b8a1257b4bc8d48ec5 293 SUPERFAMILY SSF51569 1 289 1.36E-81 T 29-03-2018 CVS48_RS09905 d6f2fcfed18b65b8a1257b4bc8d48ec5 293 Pfam PF00701 Dihydrodipicolinate synthetase family 4 287 8.5E-62 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09905 d6f2fcfed18b65b8a1257b4bc8d48ec5 293 SMART SM01130 3 292 2.3E-86 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09905 d6f2fcfed18b65b8a1257b4bc8d48ec5 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 1.8E-15 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09905 d6f2fcfed18b65b8a1257b4bc8d48ec5 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 1.8E-15 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09905 d6f2fcfed18b65b8a1257b4bc8d48ec5 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 1.8E-15 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09905 d6f2fcfed18b65b8a1257b4bc8d48ec5 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 1.8E-15 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09905 d6f2fcfed18b65b8a1257b4bc8d48ec5 293 PIRSF PIRSF001365 1 292 4.9E-76 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS09905 d6f2fcfed18b65b8a1257b4bc8d48ec5 293 Gene3D G3DSA:3.20.20.70 1 292 3.9E-85 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 319 408 3.1E-29 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 415 502 1.8E-22 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 Gene3D G3DSA:3.40.50.1100 138 312 9.2E-50 T 29-03-2018 CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 306 8.4E-81 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 Gene3D G3DSA:3.40.1020.10 328 502 3.5E-75 T 29-03-2018 CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 SUPERFAMILY SSF55021 409 502 3.2E-28 T 29-03-2018 CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 4 502 8.0E-252 T 29-03-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 Gene3D G3DSA:3.40.50.1100 27 137 1.1E-31 T 29-03-2018 CVS48_RS07835 c965c28b492d0248b2fd8c2cfabc9fe4 502 SUPERFAMILY SSF53686 5 355 2.88E-100 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS16225 4ad1f7330481005e8a37a3e07393d21c 269 SUPERFAMILY SSF49899 30 261 8.62E-16 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CVS48_RS16225 4ad1f7330481005e8a37a3e07393d21c 269 Gene3D G3DSA:2.60.120.200 22 267 2.2E-17 T 29-03-2018 CVS48_RS16225 4ad1f7330481005e8a37a3e07393d21c 269 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 102 255 2.4E-6 T 29-03-2018 CVS48_RS11905 31115211faba03c06cd4fca8f7ef3bec 148 Gene3D G3DSA:3.30.530.20 2 146 7.3E-28 T 29-03-2018 IPR023393 START-like domain CVS48_RS11905 31115211faba03c06cd4fca8f7ef3bec 148 SUPERFAMILY SSF55961 2 144 9.78E-41 T 29-03-2018 CVS48_RS11905 31115211faba03c06cd4fca8f7ef3bec 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 143 5.9E-26 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CVS48_RS05610 88f8ab5471921a0c1cbe8a4c827de4c6 478 Pfam PF00171 Aldehyde dehydrogenase family 20 474 2.2E-159 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS05610 88f8ab5471921a0c1cbe8a4c827de4c6 478 Gene3D G3DSA:3.40.309.10 268 461 7.5E-65 T 29-03-2018 CVS48_RS05610 88f8ab5471921a0c1cbe8a4c827de4c6 478 SUPERFAMILY SSF53720 8 475 1.7E-157 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CVS48_RS05610 88f8ab5471921a0c1cbe8a4c827de4c6 478 Gene3D G3DSA:3.40.605.10 2 267 2.2E-92 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CVS48_RS12890 c346e15db381d752cb6288006135faf1 167 Gene3D G3DSA:3.40.30.10 1 167 6.8E-21 T 29-03-2018 CVS48_RS12890 c346e15db381d752cb6288006135faf1 167 SUPERFAMILY SSF52833 1 166 4.48E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS12890 c346e15db381d752cb6288006135faf1 167 Pfam PF08534 Redoxin 5 164 1.9E-34 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CVS48_RS25095 3a260f78aeaed6308768f7256ff0e9b5 237 SUPERFAMILY SSF53448 20 112 1.74E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS25095 3a260f78aeaed6308768f7256ff0e9b5 237 SUPERFAMILY SSF53448 140 233 1.74E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS25095 3a260f78aeaed6308768f7256ff0e9b5 237 Gene3D G3DSA:3.90.550.10 17 235 1.4E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS25095 3a260f78aeaed6308768f7256ff0e9b5 237 Pfam PF12804 MobA-like NTP transferase domain 23 211 2.1E-28 T 29-03-2018 IPR025877 MobA-like NTP transferase CVS48_RS10030 67234dda36208881cc8059cdfc6b6684 137 Pfam PF01042 Endoribonuclease L-PSP 26 134 1.7E-19 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS10030 67234dda36208881cc8059cdfc6b6684 137 Gene3D G3DSA:3.30.1330.40 11 137 1.6E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS10030 67234dda36208881cc8059cdfc6b6684 137 SUPERFAMILY SSF55298 24 136 1.88E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 Gene3D G3DSA:3.90.1150.10 341 462 2.4E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 SUPERFAMILY SSF53383 116 460 1.9E-78 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 SUPERFAMILY SSF46785 5 75 1.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.9E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.9E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 9.9E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 Gene3D G3DSA:3.40.640.10 124 340 4.5E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 Gene3D G3DSA:1.10.10.10 1 73 1.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 SMART SM00345 12 71 3.7E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CVS48_RS02745 427fa96cde602194a06b38542c60cf1a 471 Pfam PF00155 Aminotransferase class I and II 139 447 2.2E-30 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS11125 4ce6ec26bda167b18083fae646b3c9d8 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 295 2.0E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS11125 4ce6ec26bda167b18083fae646b3c9d8 333 Gene3D G3DSA:1.10.3470.10 26 301 3.6E-33 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS25840 cf13024acadca25eee31587c63b0091d 240 Gene3D G3DSA:2.60.130.10 5 239 5.7E-57 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CVS48_RS25840 cf13024acadca25eee31587c63b0091d 240 SUPERFAMILY SSF49482 10 238 4.97E-69 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CVS48_RS25840 cf13024acadca25eee31587c63b0091d 240 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 13 42 2.3E-7 T 29-03-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CVS48_RS25840 cf13024acadca25eee31587c63b0091d 240 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 19 238 2.1E-100 T 29-03-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CVS48_RS25840 cf13024acadca25eee31587c63b0091d 240 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 83 111 - T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CVS48_RS25840 cf13024acadca25eee31587c63b0091d 240 Pfam PF00775 Dioxygenase 51 231 1.3E-56 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CVS48_RS19895 9f61df72a3f9a6dd99a2668923f771c8 282 Gene3D G3DSA:3.40.50.1000 1 268 1.1E-8 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS19895 9f61df72a3f9a6dd99a2668923f771c8 282 SUPERFAMILY SSF56784 5 223 8.78E-13 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS19895 9f61df72a3f9a6dd99a2668923f771c8 282 Pfam PF12710 haloacid dehalogenase-like hydrolase 8 210 8.8E-7 T 29-03-2018 CVS48_RS21845 37f63c14538526d5c5b450c39c8f6162 279 SUPERFAMILY SSF52540 16 255 3.74E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21845 37f63c14538526d5c5b450c39c8f6162 279 SMART SM00382 42 255 1.8E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS21845 37f63c14538526d5c5b450c39c8f6162 279 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS21845 37f63c14538526d5c5b450c39c8f6162 279 Gene3D G3DSA:3.40.50.300 2 256 7.2E-45 T 29-03-2018 CVS48_RS21845 37f63c14538526d5c5b450c39c8f6162 279 Pfam PF00005 ABC transporter 33 183 9.0E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 SUPERFAMILY SSF46785 5 65 7.58E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 Pfam PF01037 Lrp/AsnC ligand binding domain 72 149 2.8E-23 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 1.2E-22 T 29-03-2018 CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 Gene3D G3DSA:3.30.70.920 59 155 2.5E-34 T 29-03-2018 CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 Gene3D G3DSA:1.10.10.10 7 58 1.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 SUPERFAMILY SSF54909 66 157 8.18E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 SMART SM00344 6 118 8.4E-44 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 7.1E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 7.1E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS02565 ceaf832ea31c8934028c523b94e3fbc6 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 7.1E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS09655 b2937eac40c4ab1610c2b0b5f771ce64 258 PIRSF PIRSF015736 1 252 5.2E-73 T 29-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CVS48_RS09655 b2937eac40c4ab1610c2b0b5f771ce64 258 Hamap MF_00943 Maleate isomerase [maiA]. 5 251 49.79 T 29-03-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 CVS48_RS16285 3334dab382468b994e80128def2bbbc2 472 SUPERFAMILY SSF103473 263 465 2.09E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS16285 3334dab382468b994e80128def2bbbc2 472 SUPERFAMILY SSF103473 7 214 2.09E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS16285 3334dab382468b994e80128def2bbbc2 472 Pfam PF07690 Major Facilitator Superfamily 32 426 1.0E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS16285 3334dab382468b994e80128def2bbbc2 472 Gene3D G3DSA:1.20.1250.20 18 215 5.7E-32 T 29-03-2018 CVS48_RS16285 3334dab382468b994e80128def2bbbc2 472 Gene3D G3DSA:1.20.1250.20 266 471 5.4E-24 T 29-03-2018 CVS48_RS16285 3334dab382468b994e80128def2bbbc2 472 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 29 435 7.6E-73 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CVS48_RS17385 1d1dca240145514b6c92247687bf7785 163 PRINTS PR01011 Glutathione peroxidase family signature 22 39 6.9E-21 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CVS48_RS17385 1d1dca240145514b6c92247687bf7785 163 PRINTS PR01011 Glutathione peroxidase family signature 57 73 6.9E-21 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CVS48_RS17385 1d1dca240145514b6c92247687bf7785 163 PRINTS PR01011 Glutathione peroxidase family signature 123 132 6.9E-21 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CVS48_RS17385 1d1dca240145514b6c92247687bf7785 163 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 29-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CVS48_RS17385 1d1dca240145514b6c92247687bf7785 163 Gene3D G3DSA:3.40.30.10 2 161 1.2E-48 T 29-03-2018 CVS48_RS17385 1d1dca240145514b6c92247687bf7785 163 SUPERFAMILY SSF52833 3 159 2.01E-61 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS17385 1d1dca240145514b6c92247687bf7785 163 Pfam PF00255 Glutathione peroxidase 4 111 8.1E-44 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CVS48_RS17385 1d1dca240145514b6c92247687bf7785 163 PIRSF PIRSF000303 1 162 1.1E-65 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CVS48_RS01115 87a0b444bb0b7bead96c0fab202180b5 92 Gene3D G3DSA:3.30.2270.10 1 88 7.1E-35 T 29-03-2018 CVS48_RS01115 87a0b444bb0b7bead96c0fab202180b5 92 Pfam PF04267 Sarcosine oxidase, delta subunit family 4 81 2.8E-34 T 29-03-2018 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CVS48_RS06085 96b6a47535f3c9b78bbe8dc594fcdb46 324 SUPERFAMILY SSF161098 185 304 4.74E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS06085 96b6a47535f3c9b78bbe8dc594fcdb46 324 SUPERFAMILY SSF161098 90 158 4.74E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS06085 96b6a47535f3c9b78bbe8dc594fcdb46 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 8.3E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS06085 96b6a47535f3c9b78bbe8dc594fcdb46 324 Gene3D G3DSA:1.10.3720.10 2 308 1.5E-38 T 29-03-2018 CVS48_RS22625 d847617ee380a31bd597fc4f561a8b16 276 SUPERFAMILY SSF48576 5 275 1.68E-68 T 29-03-2018 IPR008949 Isoprenoid synthase domain CVS48_RS22625 d847617ee380a31bd597fc4f561a8b16 276 Gene3D G3DSA:1.10.600.10 3 276 9.1E-73 T 29-03-2018 IPR008949 Isoprenoid synthase domain CVS48_RS22625 d847617ee380a31bd597fc4f561a8b16 276 Pfam PF00494 Squalene/phytoene synthase 5 262 1.5E-64 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CVS48_RS22625 d847617ee380a31bd597fc4f561a8b16 276 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 2 275 1.2E-114 T 29-03-2018 IPR017827 Squalene synthase HpnC CVS48_RS04380 d6d1dce1daa1f810a564bce039434825 159 Pfam PF03928 Haem-degrading 7 137 2.7E-26 T 29-03-2018 IPR005624 Haem-degrading CVS48_RS04380 d6d1dce1daa1f810a564bce039434825 159 SUPERFAMILY SSF143744 2 140 2.09E-34 T 29-03-2018 CVS48_RS16220 4b4a8907f80da394f30e8ea3133994f5 649 Pfam PF05787 Bacterial protein of unknown function (DUF839) 219 556 1.5E-15 T 29-03-2018 IPR008557 Protein of unknown function DUF839 CVS48_RS13455 988610b0c96a04988614e2d0f024a766 340 Gene3D G3DSA:3.40.190.10 138 228 4.7E-19 T 29-03-2018 CVS48_RS13455 988610b0c96a04988614e2d0f024a766 340 Gene3D G3DSA:3.40.190.10 25 137 1.4E-15 T 29-03-2018 CVS48_RS13455 988610b0c96a04988614e2d0f024a766 340 SUPERFAMILY SSF53850 26 260 6.21E-46 T 29-03-2018 CVS48_RS13455 988610b0c96a04988614e2d0f024a766 340 SMART SM00062 35 265 7.1E-45 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS13455 988610b0c96a04988614e2d0f024a766 340 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 255 2.0E-30 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CVS48_RS03910 97a0794634c6bdfc3e341ed2dc956250 256 Gene3D G3DSA:3.40.50.300 1 255 4.3E-55 T 29-03-2018 CVS48_RS03910 97a0794634c6bdfc3e341ed2dc956250 256 Pfam PF00005 ABC transporter 26 181 4.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS03910 97a0794634c6bdfc3e341ed2dc956250 256 SMART SM00382 34 228 9.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS03910 97a0794634c6bdfc3e341ed2dc956250 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 8.8E-10 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS03910 97a0794634c6bdfc3e341ed2dc956250 256 SUPERFAMILY SSF52540 9 251 6.18E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09010 be60a7fb28cc4f030fa2582e726f768f 328 PIRSF PIRSF017082 1 327 1.0E-46 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09010 be60a7fb28cc4f030fa2582e726f768f 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 325 3.5E-42 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS09010 be60a7fb28cc4f030fa2582e726f768f 328 SUPERFAMILY SSF53850 90 225 3.86E-8 T 29-03-2018 CVS48_RS09010 be60a7fb28cc4f030fa2582e726f768f 328 Gene3D G3DSA:3.40.190.10 123 236 1.4E-8 T 29-03-2018 CVS48_RS02245 5c86e906876b28a565edafab7d299f83 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.9E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS02245 5c86e906876b28a565edafab7d299f83 215 SUPERFAMILY SSF46689 4 84 4.29E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS02245 5c86e906876b28a565edafab7d299f83 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 9.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS02245 5c86e906876b28a565edafab7d299f83 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 9.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS02245 5c86e906876b28a565edafab7d299f83 215 Gene3D G3DSA:1.10.10.60 1 61 3.4E-17 T 29-03-2018 CVS48_RS02245 5c86e906876b28a565edafab7d299f83 215 Gene3D G3DSA:1.10.357.10 62 194 2.8E-23 T 29-03-2018 CVS48_RS02245 5c86e906876b28a565edafab7d299f83 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CVS48_RS02245 5c86e906876b28a565edafab7d299f83 215 SUPERFAMILY SSF48498 82 195 3.68E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS13510 2cebf4aaa0b159692fde9b7e881bb3b9 386 Gene3D G3DSA:3.40.50.2300 200 355 2.0E-18 T 29-03-2018 CVS48_RS13510 2cebf4aaa0b159692fde9b7e881bb3b9 386 SUPERFAMILY SSF53822 27 379 3.62E-86 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS13510 2cebf4aaa0b159692fde9b7e881bb3b9 386 Pfam PF13458 Periplasmic binding protein 26 364 2.6E-71 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS13510 2cebf4aaa0b159692fde9b7e881bb3b9 386 Gene3D G3DSA:3.40.50.2300 23 198 2.2E-36 T 29-03-2018 CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 1.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 1.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 206 0.0099 T 29-03-2018 CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 SUPERFAMILY SSF51735 9 265 5.86E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 Gene3D G3DSA:3.40.50.720 46 269 4.8E-68 T 29-03-2018 CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 Gene3D G3DSA:3.40.50.720 2 45 7.9E-11 T 29-03-2018 CVS48_RS11830 e186aaa4a586099ffec3eb850dac8b5b 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 263 3.1E-67 T 29-03-2018 CVS48_RS18855 fdfa6c4dc1156be363e4f88aca01d598 348 Pfam PF11740 Plasmid replication region DNA-binding N-term 6 118 5.6E-22 T 29-03-2018 IPR021104 KfrA, N-terminal DNA-binding domain CVS48_RS11280 944a91fc4fb11e8ce63ca2ed5d303837 124 Gene3D G3DSA:1.10.760.10 33 124 2.5E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS11280 944a91fc4fb11e8ce63ca2ed5d303837 124 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 42 116 1.2E-12 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS11280 944a91fc4fb11e8ce63ca2ed5d303837 124 SUPERFAMILY SSF46626 17 121 8.22E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20965 0eaff51e70e381df64d04ec2163b129e 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 289 9.1E-56 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CVS48_RS20965 0eaff51e70e381df64d04ec2163b129e 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 36 320 2.5E-21 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CVS48_RS20965 0eaff51e70e381df64d04ec2163b129e 321 SUPERFAMILY SSF52283 10 142 2.08E-31 T 29-03-2018 CVS48_RS20965 0eaff51e70e381df64d04ec2163b129e 321 Gene3D G3DSA:3.40.50.720 121 292 4.6E-59 T 29-03-2018 CVS48_RS20965 0eaff51e70e381df64d04ec2163b129e 321 Gene3D G3DSA:3.40.50.720 9 120 4.9E-27 T 29-03-2018 CVS48_RS20965 0eaff51e70e381df64d04ec2163b129e 321 SUPERFAMILY SSF51735 108 290 7.76E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS10895 8990bfcd96fc61e86a9e7da2fb38ab63 352 Pfam PF06250 Protein of unknown function (DUF1016) 22 332 2.4E-122 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 CVS48_RS28310 d55f157600a99bdac5d796bbf49b031c 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.7E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS28310 d55f157600a99bdac5d796bbf49b031c 79 SUPERFAMILY SSF47336 2 76 9.16E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CVS48_RS28310 d55f157600a99bdac5d796bbf49b031c 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.537 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CVS48_RS28310 d55f157600a99bdac5d796bbf49b031c 79 Gene3D G3DSA:1.10.1200.10 1 78 1.7E-28 T 29-03-2018 CVS48_RS28310 d55f157600a99bdac5d796bbf49b031c 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 1.7E-35 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CVS48_RS28310 d55f157600a99bdac5d796bbf49b031c 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CVS48_RS28310 d55f157600a99bdac5d796bbf49b031c 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 5.0E-4 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 1.7E-13 T 29-03-2018 CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 SUPERFAMILY SSF54909 65 151 5.77E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.1E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.1E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.1E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 SMART SM00344 3 112 2.3E-27 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 Gene3D G3DSA:3.30.70.920 55 149 3.5E-21 T 29-03-2018 CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 SUPERFAMILY SSF46785 2 62 2.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 Gene3D G3DSA:1.10.10.10 1 52 1.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08995 071aae3dd2fad811c9ffcc4c1c01ccbd 154 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 5.2E-17 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CVS48_RS14465 e5a400082fd2064da6881b11bc92b517 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 105 5.9E-39 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CVS48_RS14465 e5a400082fd2064da6881b11bc92b517 108 Gene3D G3DSA:3.40.30.10 1 108 1.1E-36 T 29-03-2018 CVS48_RS14465 e5a400082fd2064da6881b11bc92b517 108 Pfam PF00085 Thioredoxin 5 105 1.6E-34 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CVS48_RS14465 e5a400082fd2064da6881b11bc92b517 108 PRINTS PR00421 Thioredoxin family signature 24 32 8.8E-10 T 29-03-2018 CVS48_RS14465 e5a400082fd2064da6881b11bc92b517 108 PRINTS PR00421 Thioredoxin family signature 32 41 8.8E-10 T 29-03-2018 CVS48_RS14465 e5a400082fd2064da6881b11bc92b517 108 PRINTS PR00421 Thioredoxin family signature 72 83 8.8E-10 T 29-03-2018 CVS48_RS14465 e5a400082fd2064da6881b11bc92b517 108 SUPERFAMILY SSF52833 3 108 9.22E-41 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS14465 e5a400082fd2064da6881b11bc92b517 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CVS48_RS14465 e5a400082fd2064da6881b11bc92b517 108 PIRSF PIRSF000077 2 108 1.3E-44 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CVS48_RS11755 c845337886f4cdb5d27f00bed92a31c1 215 Pfam PF09335 SNARE associated Golgi protein 31 161 8.2E-10 T 29-03-2018 IPR032816 SNARE associated Golgi protein CVS48_RS28510 ac7623e05a982067d887b22a64f3b6e5 345 Gene3D G3DSA:1.10.3470.10 3 339 5.2E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS28510 ac7623e05a982067d887b22a64f3b6e5 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 330 5.0E-22 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS11860 972aa3d2c00dc3e72861fa11e14be239 555 Pfam PF14707 C-terminal region of aryl-sulfatase 410 521 8.9E-9 T 29-03-2018 CVS48_RS11860 972aa3d2c00dc3e72861fa11e14be239 555 SUPERFAMILY SSF53649 32 518 5.5E-108 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS11860 972aa3d2c00dc3e72861fa11e14be239 555 Gene3D G3DSA:3.40.720.10 31 279 7.7E-53 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS11860 972aa3d2c00dc3e72861fa11e14be239 555 Gene3D G3DSA:3.40.720.10 280 409 1.6E-24 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS11860 972aa3d2c00dc3e72861fa11e14be239 555 Pfam PF00884 Sulfatase 35 381 3.1E-59 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CVS48_RS11860 972aa3d2c00dc3e72861fa11e14be239 555 Gene3D G3DSA:3.30.1120.10 410 511 6.8E-15 T 29-03-2018 CVS48_RS05270 7b4c86f031dc1e7ca4b2b67370c971b3 462 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 8 458 6.1E-119 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CVS48_RS05270 7b4c86f031dc1e7ca4b2b67370c971b3 462 PIRSF PIRSF002746 4 460 6.3E-146 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CVS48_RS05270 7b4c86f031dc1e7ca4b2b67370c971b3 462 Pfam PF02447 GntP family permease 9 457 5.4E-125 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CVS48_RS06100 81c7ef383687c205aac3bc2369cc7566 152 Gene3D G3DSA:3.40.630.30 3 152 1.8E-24 T 29-03-2018 CVS48_RS06100 81c7ef383687c205aac3bc2369cc7566 152 Pfam PF00583 Acetyltransferase (GNAT) family 46 129 6.2E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS06100 81c7ef383687c205aac3bc2369cc7566 152 SUPERFAMILY SSF55729 1 148 7.2E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS14690 be221da209244f2ed2c102935080384d 164 SUPERFAMILY SSF47413 19 60 2.78E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS14690 be221da209244f2ed2c102935080384d 164 Gene3D G3DSA:1.10.260.40 2 95 2.8E-8 T 29-03-2018 CVS48_RS14690 be221da209244f2ed2c102935080384d 164 Pfam PF13413 Helix-turn-helix domain 24 83 3.6E-19 T 29-03-2018 CVS48_RS09725 b99377042aafefca863313f6f360b395 197 Gene3D G3DSA:3.40.630.30 6 171 1.7E-10 T 29-03-2018 CVS48_RS09725 b99377042aafefca863313f6f360b395 197 SUPERFAMILY SSF55729 30 155 5.41E-10 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS09725 b99377042aafefca863313f6f360b395 197 Pfam PF00583 Acetyltransferase (GNAT) family 44 150 1.5E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS06165 b19c48c1fedb94ce81e6567077640719 274 SUPERFAMILY SSF55729 103 261 9.75E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS06165 b19c48c1fedb94ce81e6567077640719 274 Pfam PF00583 Acetyltransferase (GNAT) family 197 257 2.8E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS06165 b19c48c1fedb94ce81e6567077640719 274 Gene3D G3DSA:3.40.630.30 101 273 2.4E-19 T 29-03-2018 CVS48_RS11330 71cbe5689b89e00bc7c3e1e821d8a1e3 341 PIRSF PIRSF017082 9 341 2.3E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11330 71cbe5689b89e00bc7c3e1e821d8a1e3 341 SUPERFAMILY SSF53850 130 295 1.21E-14 T 29-03-2018 CVS48_RS11330 71cbe5689b89e00bc7c3e1e821d8a1e3 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 67 336 8.6E-87 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11330 71cbe5689b89e00bc7c3e1e821d8a1e3 341 Gene3D G3DSA:3.40.190.10 142 251 5.5E-13 T 29-03-2018 CVS48_RS10695 8743832f67fa7d7381ebf1abd9eb7ca2 380 Gene3D G3DSA:3.40.50.2000 4 198 3.8E-23 T 29-03-2018 CVS48_RS10695 8743832f67fa7d7381ebf1abd9eb7ca2 380 Pfam PF13439 Glycosyltransferase Family 4 22 180 1.9E-21 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS10695 8743832f67fa7d7381ebf1abd9eb7ca2 380 SUPERFAMILY SSF53756 11 373 3.37E-79 T 29-03-2018 CVS48_RS10695 8743832f67fa7d7381ebf1abd9eb7ca2 380 Gene3D G3DSA:3.40.50.2000 199 359 2.8E-41 T 29-03-2018 CVS48_RS10695 8743832f67fa7d7381ebf1abd9eb7ca2 380 Pfam PF00534 Glycosyl transferases group 1 197 353 2.4E-34 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS13155 d1bdac622c9a5f33ebabcc3109bdcaa5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13155 d1bdac622c9a5f33ebabcc3109bdcaa5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13155 d1bdac622c9a5f33ebabcc3109bdcaa5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13155 d1bdac622c9a5f33ebabcc3109bdcaa5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13155 d1bdac622c9a5f33ebabcc3109bdcaa5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS13155 d1bdac622c9a5f33ebabcc3109bdcaa5 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 259 2.5E-81 T 29-03-2018 CVS48_RS13155 d1bdac622c9a5f33ebabcc3109bdcaa5 262 Gene3D G3DSA:3.40.50.720 8 261 1.1E-45 T 29-03-2018 CVS48_RS13155 d1bdac622c9a5f33ebabcc3109bdcaa5 262 SUPERFAMILY SSF51735 14 260 6.44E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS13155 d1bdac622c9a5f33ebabcc3109bdcaa5 262 PIRSF PIRSF000094 9 262 6.0E-88 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS09630 910a0823dbffada34f35dd96f73d5fd0 181 SUPERFAMILY SSF55781 26 158 4.71E-10 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09630 910a0823dbffada34f35dd96f73d5fd0 181 Pfam PF13185 GAF domain 29 156 6.0E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 CVS48_RS09630 910a0823dbffada34f35dd96f73d5fd0 181 Gene3D G3DSA:3.30.450.40 1 177 5.3E-11 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS28930 0e4e354ddad479541d357555e4a91893 270 Pfam PF14302 Domain of unknown function (DUF4377) 179 265 1.9E-24 T 29-03-2018 IPR025485 Domain of unknown function DUF4377 CVS48_RS28930 0e4e354ddad479541d357555e4a91893 270 Pfam PF03724 META domain 45 159 1.9E-16 T 29-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ CVS48_RS13490 37b12fac7bba7a87e1aa34a5b114a9f9 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS13490 37b12fac7bba7a87e1aa34a5b114a9f9 236 SUPERFAMILY SSF52540 3 233 6.74E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS13490 37b12fac7bba7a87e1aa34a5b114a9f9 236 Gene3D G3DSA:3.40.50.300 1 234 2.9E-55 T 29-03-2018 CVS48_RS13490 37b12fac7bba7a87e1aa34a5b114a9f9 236 SMART SM00382 29 213 3.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS13490 37b12fac7bba7a87e1aa34a5b114a9f9 236 Pfam PF00005 ABC transporter 20 164 8.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05710 eac0e18896bb05050e037579e2c88c16 152 Pfam PF04361 Protein of unknown function (DUF494) 1 152 8.1E-51 T 29-03-2018 IPR007456 Smg CVS48_RS05710 eac0e18896bb05050e037579e2c88c16 152 Hamap MF_00598 Protein Smg [smg]. 1 152 26.95 T 29-03-2018 IPR007456 Smg CVS48_RS22835 a1618b911b3fc02251ecc3ce10a5afed 307 Gene3D G3DSA:1.10.3720.10 3 294 2.7E-44 T 29-03-2018 CVS48_RS22835 a1618b911b3fc02251ecc3ce10a5afed 307 SUPERFAMILY SSF161098 92 291 4.19E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22835 a1618b911b3fc02251ecc3ce10a5afed 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 305 2.8E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28525 cef73b2727413a69a704d20eaaf89119 198 Pfam PF02361 Cobalt transport protein 16 196 8.3E-16 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CVS48_RS02975 64846bb0b23ca97db4ff67367c581996 218 Gene3D G3DSA:3.90.280.10 1 204 4.4E-50 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CVS48_RS02975 64846bb0b23ca97db4ff67367c581996 218 Pfam PF01161 Phosphatidylethanolamine-binding protein 31 201 1.3E-40 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CVS48_RS02975 64846bb0b23ca97db4ff67367c581996 218 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 80 201 3.1E-19 T 29-03-2018 IPR005247 YbhB/YbcL CVS48_RS02975 64846bb0b23ca97db4ff67367c581996 218 SUPERFAMILY SSF49777 1 203 1.83E-44 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CVS48_RS20240 27072dc389d9101ca2fe15ff86a4d3f3 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 49 221 5.0E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20240 27072dc389d9101ca2fe15ff86a4d3f3 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 115 2.1E-17 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS20240 27072dc389d9101ca2fe15ff86a4d3f3 229 SUPERFAMILY SSF161098 11 204 6.15E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20240 27072dc389d9101ca2fe15ff86a4d3f3 229 Gene3D G3DSA:1.10.3720.10 2 225 4.4E-40 T 29-03-2018 CVS48_RS20075 a4a0e51a8e607244648e6eb5abb3de02 381 Gene3D G3DSA:3.40.1710.10 46 201 9.9E-31 T 29-03-2018 CVS48_RS20075 a4a0e51a8e607244648e6eb5abb3de02 381 Pfam PF12698 ABC-2 family transporter protein 32 373 3.5E-50 T 29-03-2018 CVS48_RS26360 5fe50e357e922057ab9f050398f04568 176 Gene3D G3DSA:1.20.1290.10 15 176 2.3E-42 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS26360 5fe50e357e922057ab9f050398f04568 176 SUPERFAMILY SSF69118 15 174 4.01E-38 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS26360 5fe50e357e922057ab9f050398f04568 176 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 109 5.9E-12 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS07250 e0262d89c19c36f68b15037e0062ceaa 154 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 112 146 1.2E-10 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CVS48_RS07250 e0262d89c19c36f68b15037e0062ceaa 154 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 36 144 9.8E-43 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 CVS48_RS07250 e0262d89c19c36f68b15037e0062ceaa 154 SUPERFAMILY SSF109635 20 113 1.44E-28 T 29-03-2018 CVS48_RS07250 e0262d89c19c36f68b15037e0062ceaa 154 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 117 141 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site CVS48_RS07250 e0262d89c19c36f68b15037e0062ceaa 154 SUPERFAMILY SSF57716 114 152 2.0E-8 T 29-03-2018 CVS48_RS07250 e0262d89c19c36f68b15037e0062ceaa 154 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 32 153 28.363 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 CVS48_RS26780 4e2c5edc88fdbf3506503e58ab68ff22 176 Gene3D G3DSA:3.90.80.10 2 176 1.0E-54 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CVS48_RS26780 4e2c5edc88fdbf3506503e58ab68ff22 176 SUPERFAMILY SSF50324 4 175 1.13E-67 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CVS48_RS26780 4e2c5edc88fdbf3506503e58ab68ff22 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.57 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CVS48_RS26780 4e2c5edc88fdbf3506503e58ab68ff22 176 Pfam PF00719 Inorganic pyrophosphatase 18 174 5.4E-54 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 220 6.6E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 SMART SM00448 14 128 5.7E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 6.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 6.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 6.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 SMART SM00421 163 220 7.0E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 Pfam PF00072 Response regulator receiver domain 16 122 7.6E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 Gene3D G3DSA:3.40.50.2300 14 140 2.0E-24 T 29-03-2018 CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 SUPERFAMILY SSF52172 15 194 7.05E-25 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS25630 e0848d17ca94d072f524cd90c1d1a931 227 Gene3D G3DSA:1.10.10.10 141 227 7.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19175 51a49498c6563e758e26965fca440c33 390 Pfam PF00149 Calcineurin-like phosphoesterase 160 328 1.6E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS19175 51a49498c6563e758e26965fca440c33 390 Gene3D G3DSA:3.60.21.10 157 381 5.5E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS19175 51a49498c6563e758e26965fca440c33 390 SUPERFAMILY SSF56300 160 383 2.13E-37 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS17010 adfe2c9d42b2679e1be9ab00475e2cbc 267 Gene3D G3DSA:2.30.110.10 12 122 3.9E-4 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS17010 adfe2c9d42b2679e1be9ab00475e2cbc 267 Gene3D G3DSA:2.40.10.220 123 267 1.4E-11 T 29-03-2018 CVS48_RS23780 3646655e560ddc2c19ede7562b67ba11 438 Pfam PF01943 Polysaccharide biosynthesis protein 15 290 4.2E-17 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CVS48_RS15325 df76a3fc1b481777620cedac26416ff1 135 SUPERFAMILY SSF50022 16 123 1.57E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS15325 df76a3fc1b481777620cedac26416ff1 135 Pfam PF00355 Rieske [2Fe-2S] domain 19 106 2.6E-7 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS15325 df76a3fc1b481777620cedac26416ff1 135 Gene3D G3DSA:2.102.10.10 4 133 1.9E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS00100 1b56367d1d2ca7279639477769b66cc2 401 Gene3D G3DSA:1.20.91.10 220 303 1.3E-10 T 29-03-2018 CVS48_RS00100 1b56367d1d2ca7279639477769b66cc2 401 Pfam PF00999 Sodium/hydrogen exchanger family 5 367 2.9E-61 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CVS48_RS06520 d7cb684a5e711f216597880834155612 121 Gene3D G3DSA:3.30.420.100 1 121 2.2E-36 T 29-03-2018 CVS48_RS06520 d7cb684a5e711f216597880834155612 121 SUPERFAMILY SSF53137 3 119 1.88E-49 T 29-03-2018 CVS48_RS06520 d7cb684a5e711f216597880834155612 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 121 4.4E-35 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS06520 d7cb684a5e711f216597880834155612 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 121 2.8E-36 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS06520 d7cb684a5e711f216597880834155612 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 121 26.071 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS14335 6bf7900142e2d5ff7563017e90eeabb6 195 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 65 3.3E-7 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CVS48_RS14335 6bf7900142e2d5ff7563017e90eeabb6 195 Pfam PF01467 Cytidylyltransferase-like 6 169 1.2E-23 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CVS48_RS14335 6bf7900142e2d5ff7563017e90eeabb6 195 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 194 2.7E-42 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CVS48_RS14335 6bf7900142e2d5ff7563017e90eeabb6 195 SUPERFAMILY SSF52374 2 195 2.44E-44 T 29-03-2018 CVS48_RS14335 6bf7900142e2d5ff7563017e90eeabb6 195 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 195 27.644 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CVS48_RS14335 6bf7900142e2d5ff7563017e90eeabb6 195 Gene3D G3DSA:3.40.50.620 1 195 1.6E-45 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS24855 7b027f834417dd077c7e6d89d52d4790 282 Pfam PF07120 Protein of unknown function (DUF1376) 2 87 3.4E-29 T 29-03-2018 IPR010781 Protein of unknown function DUF1376 CVS48_RS06735 e7142fc005b15cf868a3eee113aff5d5 451 SUPERFAMILY SSF56112 110 177 6.93E-8 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS06735 e7142fc005b15cf868a3eee113aff5d5 451 SUPERFAMILY SSF56112 32 74 6.93E-8 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS06735 e7142fc005b15cf868a3eee113aff5d5 451 Gene3D G3DSA:1.10.510.10 23 325 7.2E-8 T 29-03-2018 CVS48_RS06735 e7142fc005b15cf868a3eee113aff5d5 451 PRINTS PR01217 Proline rich extensin signature 305 326 3.4E-9 T 29-03-2018 CVS48_RS06735 e7142fc005b15cf868a3eee113aff5d5 451 PRINTS PR01217 Proline rich extensin signature 350 367 3.4E-9 T 29-03-2018 CVS48_RS06735 e7142fc005b15cf868a3eee113aff5d5 451 PRINTS PR01217 Proline rich extensin signature 238 250 3.4E-9 T 29-03-2018 CVS48_RS06735 e7142fc005b15cf868a3eee113aff5d5 451 PRINTS PR01217 Proline rich extensin signature 255 271 3.4E-9 T 29-03-2018 CVS48_RS06735 e7142fc005b15cf868a3eee113aff5d5 451 PRINTS PR01217 Proline rich extensin signature 328 344 3.4E-9 T 29-03-2018 CVS48_RS28965 23abf6eaa9e5b9158b1d581a450744f8 199 Gene3D G3DSA:3.40.109.10 4 198 3.0E-21 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CVS48_RS28965 23abf6eaa9e5b9158b1d581a450744f8 199 Pfam PF00881 Nitroreductase family 10 177 3.2E-11 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CVS48_RS28965 23abf6eaa9e5b9158b1d581a450744f8 199 SUPERFAMILY SSF55469 5 197 2.14E-63 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CVS48_RS05465 92a1a6318799523197e54666f8991e7c 405 Pfam PF13458 Periplasmic binding protein 33 368 2.3E-83 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS05465 92a1a6318799523197e54666f8991e7c 405 Gene3D G3DSA:3.40.50.2300 17 167 5.9E-17 T 29-03-2018 CVS48_RS05465 92a1a6318799523197e54666f8991e7c 405 SUPERFAMILY SSF53822 33 403 3.03E-85 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS05465 92a1a6318799523197e54666f8991e7c 405 Gene3D G3DSA:3.40.50.2300 168 340 1.2E-30 T 29-03-2018 CVS48_RS27775 6e53e8c085c3ea707e3ba6343deb61e1 339 SUPERFAMILY SSF53850 59 330 6.34E-49 T 29-03-2018 CVS48_RS27775 6e53e8c085c3ea707e3ba6343deb61e1 339 Gene3D G3DSA:3.40.190.10 148 281 1.9E-25 T 29-03-2018 CVS48_RS27775 6e53e8c085c3ea707e3ba6343deb61e1 339 Gene3D G3DSA:3.40.190.10 26 147 0.0073 T 29-03-2018 CVS48_RS27775 6e53e8c085c3ea707e3ba6343deb61e1 339 Pfam PF13343 Bacterial extracellular solute-binding protein 85 309 1.0E-28 T 29-03-2018 CVS48_RS27775 6e53e8c085c3ea707e3ba6343deb61e1 339 PIRSF PIRSF002825 8 333 5.4E-57 T 29-03-2018 IPR026045 Ferric binding protein CVS48_RS13830 b9d282429469d5a8001dcb4be5ef1f2a 140 Pfam PF14282 FlxA-like protein 62 135 4.5E-8 T 29-03-2018 IPR025577 FlxA-like protein CVS48_RS19815 a3e570f614682f8d9f45a79f77f7705e 212 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 7 207 2.4E-56 T 29-03-2018 CVS48_RS19815 a3e570f614682f8d9f45a79f77f7705e 212 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 133 148 - T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CVS48_RS19815 a3e570f614682f8d9f45a79f77f7705e 212 SUPERFAMILY SSF53335 7 209 2.71E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS19815 a3e570f614682f8d9f45a79f77f7705e 212 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 2 212 34.688 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CVS48_RS19815 a3e570f614682f8d9f45a79f77f7705e 212 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 3 209 3.0E-59 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CVS48_RS19815 a3e570f614682f8d9f45a79f77f7705e 212 Gene3D G3DSA:3.40.50.150 2 211 1.3E-39 T 29-03-2018 CVS48_RS16630 0994143f8eab26742b3c74f9f1c5b075 391 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 58 289 2.4E-13 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS16630 0994143f8eab26742b3c74f9f1c5b075 391 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 371 1.6E-79 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS16630 0994143f8eab26742b3c74f9f1c5b075 391 SUPERFAMILY SSF111369 46 296 7.19E-87 T 29-03-2018 CVS48_RS16630 0994143f8eab26742b3c74f9f1c5b075 391 Gene3D G3DSA:1.20.1600.10 21 339 1.6E-31 T 29-03-2018 CVS48_RS24365 faaf05c2324ad9a63a3216ae456793cf 113 Pfam PF05939 Phage minor tail protein 4 111 1.0E-31 T 29-03-2018 IPR010265 Bacteriophage lambda, GpM, minor tail CVS48_RS21365 3e66f4f1bc725e221cb6e3d9a3138085 219 Pfam PF04120 Low affinity iron permease 43 159 5.1E-47 T 29-03-2018 IPR007251 Low affinity iron permease, Fet4 GO:0055085 CVS48_RS10760 3da77dd7465dd536fc045b6fa58d10be 187 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 50 178 4.2E-27 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS08760 1541c50d4d277661c984c62ca794758c 421 Gene3D G3DSA:3.40.50.2300 186 366 1.6E-28 T 29-03-2018 CVS48_RS08760 1541c50d4d277661c984c62ca794758c 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 55 71 1.2E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS08760 1541c50d4d277661c984c62ca794758c 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 77 93 1.2E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS08760 1541c50d4d277661c984c62ca794758c 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 291 309 1.2E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS08760 1541c50d4d277661c984c62ca794758c 421 Pfam PF13458 Periplasmic binding protein 54 400 1.9E-57 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS08760 1541c50d4d277661c984c62ca794758c 421 SUPERFAMILY SSF53822 54 408 4.35E-75 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS08760 1541c50d4d277661c984c62ca794758c 421 Gene3D G3DSA:3.40.50.2300 38 185 5.7E-29 T 29-03-2018 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 SUPERFAMILY SSF56235 44 584 1.1E-168 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 297 316 6.6E-68 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 427 445 6.6E-68 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 423 6.6E-68 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 167 186 6.6E-68 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 74 99 6.6E-68 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 488 505 6.6E-68 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 464 479 6.6E-68 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 149 167 6.6E-68 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 267 283 6.6E-68 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 53 577 8.7E-131 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS01770 98713e04277dac5ebfdcd2ba387dbf25 585 Pfam PF01019 Gamma-glutamyltranspeptidase 67 580 6.1E-155 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CVS48_RS17765 48d63da8ce43f670d47d923242eecde5 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 8.9E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17765 48d63da8ce43f670d47d923242eecde5 328 PIRSF PIRSF017082 1 327 1.6E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17765 48d63da8ce43f670d47d923242eecde5 328 SUPERFAMILY SSF53850 105 291 1.41E-14 T 29-03-2018 CVS48_RS17765 48d63da8ce43f670d47d923242eecde5 328 Gene3D G3DSA:3.40.190.10 127 264 2.0E-12 T 29-03-2018 CVS48_RS27600 ddd31dbb745604401b1ad5ee6d2f8708 281 PIRSF PIRSF012318 14 280 2.1E-97 T 29-03-2018 IPR011197 Uncharacterised conserved protein UCP012318 CVS48_RS27600 ddd31dbb745604401b1ad5ee6d2f8708 281 Gene3D G3DSA:1.20.1260.10 70 275 9.6E-43 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS27600 ddd31dbb745604401b1ad5ee6d2f8708 281 SUPERFAMILY SSF47240 85 250 9.7E-20 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS27600 ddd31dbb745604401b1ad5ee6d2f8708 281 Pfam PF04305 Protein of unknown function (DUF455) 34 268 6.1E-95 T 29-03-2018 IPR007402 Protein of unknown function DUF455 CVS48_RS21795 4b970e50271ef33eda902e585bc28c11 426 Pfam PF12704 MacB-like periplasmic core domain 38 253 4.1E-19 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CVS48_RS21795 4b970e50271ef33eda902e585bc28c11 426 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 6 425 4.8E-140 T 29-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 CVS48_RS21795 4b970e50271ef33eda902e585bc28c11 426 Pfam PF02687 FtsX-like permease family 312 419 2.1E-13 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CVS48_RS04765 0c8cf2d6e3b689ee18017c1b22e3b47c 297 Gene3D G3DSA:3.40.190.10 177 264 1.5E-21 T 29-03-2018 CVS48_RS04765 0c8cf2d6e3b689ee18017c1b22e3b47c 297 SUPERFAMILY SSF46785 2 86 2.73E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04765 0c8cf2d6e3b689ee18017c1b22e3b47c 297 SUPERFAMILY SSF53850 95 294 8.69E-43 T 29-03-2018 CVS48_RS04765 0c8cf2d6e3b689ee18017c1b22e3b47c 297 Gene3D G3DSA:1.10.10.10 1 94 3.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS04765 0c8cf2d6e3b689ee18017c1b22e3b47c 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.4E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS04765 0c8cf2d6e3b689ee18017c1b22e3b47c 297 Pfam PF03466 LysR substrate binding domain 96 292 1.1E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS04765 0c8cf2d6e3b689ee18017c1b22e3b47c 297 Gene3D G3DSA:3.40.190.10 95 176 3.0E-20 T 29-03-2018 CVS48_RS05010 caeb5a91451e17c599b3fc83787edd55 252 SUPERFAMILY SSF143422 35 107 8.44E-5 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CVS48_RS17100 dfaed5ff4d96d3272bfae04f16758544 160 Gene3D G3DSA:1.20.1550.10 1 160 1.4E-27 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CVS48_RS17100 dfaed5ff4d96d3272bfae04f16758544 160 Pfam PF02600 Disulfide bond formation protein DsbB 8 151 5.7E-31 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CVS48_RS17100 dfaed5ff4d96d3272bfae04f16758544 160 SUPERFAMILY SSF158442 10 151 1.31E-26 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CVS48_RS24420 08bdcac312603541ef348a5f74839c2a 506 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 30 482 1.3E-91 T 29-03-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 CVS48_RS24420 08bdcac312603541ef348a5f74839c2a 506 Pfam PF05136 Phage portal protein, lambda family 32 376 3.5E-109 T 29-03-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 CVS48_RS02370 0ecf74deed11e54fe33c31ca3a1c9f77 136 SUPERFAMILY SSF54637 18 135 2.96E-34 T 29-03-2018 IPR029069 HotDog domain CVS48_RS02370 0ecf74deed11e54fe33c31ca3a1c9f77 136 Pfam PF03061 Thioesterase superfamily 32 107 4.3E-17 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CVS48_RS02370 0ecf74deed11e54fe33c31ca3a1c9f77 136 Gene3D G3DSA:3.10.129.10 4 136 7.5E-32 T 29-03-2018 CVS48_RS16535 fd9cea843969fc9a6e06defe0a92dbd1 182 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 24 178 4.2E-47 T 29-03-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 CVS48_RS16535 fd9cea843969fc9a6e06defe0a92dbd1 182 Gene3D G3DSA:3.20.19.10 18 182 2.0E-40 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS16535 fd9cea843969fc9a6e06defe0a92dbd1 182 Pfam PF00694 Aconitase C-terminal domain 65 124 2.3E-16 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CVS48_RS16535 fd9cea843969fc9a6e06defe0a92dbd1 182 SUPERFAMILY SSF52016 22 179 1.1E-39 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CVS48_RS03225 d6b4c1fbb9ed38ac726edaffdc2558d8 365 Gene3D G3DSA:3.40.190.10 153 317 7.4E-28 T 29-03-2018 CVS48_RS03225 d6b4c1fbb9ed38ac726edaffdc2558d8 365 Gene3D G3DSA:3.40.190.10 39 152 1.8E-7 T 29-03-2018 CVS48_RS03225 d6b4c1fbb9ed38ac726edaffdc2558d8 365 Pfam PF13416 Bacterial extracellular solute-binding protein 62 322 4.1E-21 T 29-03-2018 CVS48_RS03225 d6b4c1fbb9ed38ac726edaffdc2558d8 365 SUPERFAMILY SSF53850 47 343 2.6E-56 T 29-03-2018 CVS48_RS14210 4914ab47490c993ca9a2d5d57d2b27db 350 SUPERFAMILY SSF53850 29 346 1.09E-56 T 29-03-2018 CVS48_RS14210 4914ab47490c993ca9a2d5d57d2b27db 350 Gene3D G3DSA:3.40.190.10 30 148 1.1E-14 T 29-03-2018 CVS48_RS14210 4914ab47490c993ca9a2d5d57d2b27db 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 152 166 1.4E-7 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS14210 4914ab47490c993ca9a2d5d57d2b27db 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 250 269 1.4E-7 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS14210 4914ab47490c993ca9a2d5d57d2b27db 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 98 111 1.4E-7 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS14210 4914ab47490c993ca9a2d5d57d2b27db 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 54 75 1.4E-7 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS14210 4914ab47490c993ca9a2d5d57d2b27db 350 Pfam PF13416 Bacterial extracellular solute-binding protein 48 310 3.1E-27 T 29-03-2018 CVS48_RS14210 4914ab47490c993ca9a2d5d57d2b27db 350 Gene3D G3DSA:3.40.190.10 149 302 1.1E-27 T 29-03-2018 CVS48_RS08030 93e3558634c428fab010c77da5cae540 251 SUPERFAMILY SSF69572 2 247 3.92E-87 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CVS48_RS08030 93e3558634c428fab010c77da5cae540 251 Pfam PF00899 ThiF family 9 243 2.9E-65 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CVS48_RS08030 93e3558634c428fab010c77da5cae540 251 Gene3D G3DSA:3.40.50.720 1 248 1.6E-73 T 29-03-2018 CVS48_RS21015 fdd976b2fd834e0deac6fc960e873a02 324 Gene3D G3DSA:1.10.3720.10 2 308 2.5E-39 T 29-03-2018 CVS48_RS21015 fdd976b2fd834e0deac6fc960e873a02 324 SUPERFAMILY SSF161098 90 306 2.62E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS21015 fdd976b2fd834e0deac6fc960e873a02 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 1.4E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS12765 ca6b47b5df17d35b3719f8f01d0e054f 142 PRINTS PR01438 Universal stress protein signature 1 18 1.7E-14 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS12765 ca6b47b5df17d35b3719f8f01d0e054f 142 PRINTS PR01438 Universal stress protein signature 120 142 1.7E-14 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS12765 ca6b47b5df17d35b3719f8f01d0e054f 142 PRINTS PR01438 Universal stress protein signature 102 114 1.7E-14 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS12765 ca6b47b5df17d35b3719f8f01d0e054f 142 SUPERFAMILY SSF52402 3 142 8.37E-31 T 29-03-2018 CVS48_RS12765 ca6b47b5df17d35b3719f8f01d0e054f 142 Pfam PF00582 Universal stress protein family 3 142 3.4E-25 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS12765 ca6b47b5df17d35b3719f8f01d0e054f 142 Gene3D G3DSA:3.40.50.620 2 142 2.9E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS23035 91b59eaa269e682423f251dc9b24c9d4 184 Gene3D G3DSA:2.70.70.10 32 182 5.0E-31 T 29-03-2018 CVS48_RS23035 91b59eaa269e682423f251dc9b24c9d4 184 Pfam PF01551 Peptidase family M23 77 173 5.9E-24 T 29-03-2018 IPR016047 Peptidase M23 CVS48_RS23035 91b59eaa269e682423f251dc9b24c9d4 184 SUPERFAMILY SSF51261 44 176 6.8E-34 T 29-03-2018 IPR011055 Duplicated hybrid motif CVS48_RS05920 0b6506a46f24e0cc0e84fe6fea1bcae2 389 Pfam PF01266 FAD dependent oxidoreductase 9 349 2.0E-57 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS05920 0b6506a46f24e0cc0e84fe6fea1bcae2 389 Gene3D G3DSA:3.40.50.720 7 73 1.5E-7 T 29-03-2018 CVS48_RS05920 0b6506a46f24e0cc0e84fe6fea1bcae2 389 Gene3D G3DSA:3.30.9.10 74 306 5.7E-34 T 29-03-2018 CVS48_RS05920 0b6506a46f24e0cc0e84fe6fea1bcae2 389 SUPERFAMILY SSF51905 7 219 1.04E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05920 0b6506a46f24e0cc0e84fe6fea1bcae2 389 SUPERFAMILY SSF51905 310 369 1.04E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS05920 0b6506a46f24e0cc0e84fe6fea1bcae2 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.2E-6 T 29-03-2018 CVS48_RS05920 0b6506a46f24e0cc0e84fe6fea1bcae2 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 181 196 1.2E-6 T 29-03-2018 CVS48_RS05920 0b6506a46f24e0cc0e84fe6fea1bcae2 389 SUPERFAMILY SSF54373 229 305 4.71E-6 T 29-03-2018 CVS48_RS22985 83213e2bd51be50eb555bbff2e4a4eb6 298 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 23 62 4.3E-11 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS22985 83213e2bd51be50eb555bbff2e4a4eb6 298 SUPERFAMILY SSF161098 93 280 3.53E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22985 83213e2bd51be50eb555bbff2e4a4eb6 298 Gene3D G3DSA:1.10.3720.10 26 288 4.5E-38 T 29-03-2018 CVS48_RS22985 83213e2bd51be50eb555bbff2e4a4eb6 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 292 1.7E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03390 552d99083035a99633ea3b9f1caad80c 392 SUPERFAMILY SSF53822 29 386 5.34E-84 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS03390 552d99083035a99633ea3b9f1caad80c 392 Gene3D G3DSA:3.40.50.2300 16 189 5.6E-27 T 29-03-2018 CVS48_RS03390 552d99083035a99633ea3b9f1caad80c 392 Pfam PF13458 Periplasmic binding protein 28 362 2.2E-71 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS03390 552d99083035a99633ea3b9f1caad80c 392 Gene3D G3DSA:3.40.50.2300 191 352 8.9E-25 T 29-03-2018 CVS48_RS12790 2b70f25d6ad079f61c8257591a8b7e22 174 Pfam PF02417 Chromate transporter 7 169 1.0E-32 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CVS48_RS12790 2b70f25d6ad079f61c8257591a8b7e22 174 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 18 32 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 SUPERFAMILY SSF46785 17 98 5.63E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 Gene3D G3DSA:3.40.190.10 105 193 1.9E-13 T 29-03-2018 CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 Pfam PF03466 LysR substrate binding domain 107 311 4.1E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 79 6.4E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 56 3.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 46 3.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 56 67 3.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 Gene3D G3DSA:3.40.190.10 194 282 3.6E-14 T 29-03-2018 CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 Gene3D G3DSA:1.10.10.10 2 103 9.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12395 14e7a6216052f7128843b51e508ace82 326 SUPERFAMILY SSF53850 107 316 1.09E-34 T 29-03-2018 CVS48_RS24120 d820f76a8073d2a3f3ba9dd1181f2851 504 Gene3D G3DSA:1.10.760.10 92 174 0.0061 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS24120 d820f76a8073d2a3f3ba9dd1181f2851 504 PIRSF PIRSF028099 2 504 1.3E-179 T 29-03-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase CVS48_RS24120 d820f76a8073d2a3f3ba9dd1181f2851 504 Gene3D G3DSA:1.10.760.10 347 504 2.7E-29 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS24120 d820f76a8073d2a3f3ba9dd1181f2851 504 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 56 504 1.1E-133 T 29-03-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase CVS48_RS24120 d820f76a8073d2a3f3ba9dd1181f2851 504 SUPERFAMILY SSF46626 362 504 1.7E-28 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS13910 5c06f91a05af113a5a44bb02603b4083 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 9.7E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13910 5c06f91a05af113a5a44bb02603b4083 328 Gene3D G3DSA:3.40.190.10 128 295 8.6E-14 T 29-03-2018 CVS48_RS13910 5c06f91a05af113a5a44bb02603b4083 328 SUPERFAMILY SSF53850 90 287 2.1E-18 T 29-03-2018 CVS48_RS13910 5c06f91a05af113a5a44bb02603b4083 328 PIRSF PIRSF017082 2 328 2.9E-92 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS26830 915131dbab8c2c7eae31ad8d8b2f095e 765 PIRSF PIRSF000382 1 765 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CVS48_RS26830 915131dbab8c2c7eae31ad8d8b2f095e 765 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 763 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CVS48_RS26830 915131dbab8c2c7eae31ad8d8b2f095e 765 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 764 37.554 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CVS48_RS26830 915131dbab8c2c7eae31ad8d8b2f095e 765 SUPERFAMILY SSF51726 5 401 6.93E-109 T 29-03-2018 CVS48_RS26830 915131dbab8c2c7eae31ad8d8b2f095e 765 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 438 759 7.5E-156 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CVS48_RS26830 915131dbab8c2c7eae31ad8d8b2f095e 765 Gene3D G3DSA:3.20.20.210 2 396 6.8E-147 T 29-03-2018 CVS48_RS26830 915131dbab8c2c7eae31ad8d8b2f095e 765 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 320 1.0E-119 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CVS48_RS26830 915131dbab8c2c7eae31ad8d8b2f095e 765 Gene3D G3DSA:3.20.20.210 397 765 1.5E-125 T 29-03-2018 CVS48_RS26830 915131dbab8c2c7eae31ad8d8b2f095e 765 SUPERFAMILY SSF51726 416 763 4.19E-116 T 29-03-2018 CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 Gene3D G3DSA:3.10.580.10 195 312 1.9E-20 T 29-03-2018 CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 SUPERFAMILY SSF53697 2 311 1.33E-58 T 29-03-2018 CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 Pfam PF01380 SIS domain 37 167 1.6E-29 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 Pfam PF00571 CBS domain 198 251 2.8E-6 T 29-03-2018 IPR000644 CBS domain CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 Pfam PF00571 CBS domain 263 307 7.1E-6 T 29-03-2018 IPR000644 CBS domain CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 SMART SM00116 205 252 0.073 T 29-03-2018 IPR000644 CBS domain CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 SMART SM00116 269 317 0.0088 T 29-03-2018 IPR000644 CBS domain CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 41 307 3.5E-106 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 Gene3D G3DSA:3.40.50.10490 1 194 1.0E-52 T 29-03-2018 CVS48_RS19345 3654fa5f6c55eb3eecfafd98bda8cba9 319 PIRSF PIRSF004692 1 317 1.6E-125 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CVS48_RS02815 d3082a0d7f8bcfe3128d0c20ca9a5606 150 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 1.9E-50 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CVS48_RS02815 d3082a0d7f8bcfe3128d0c20ca9a5606 150 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 32.964 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CVS48_RS04080 80fd2f75fa27641eed3a7a333ca95c6e 271 Gene3D G3DSA:1.10.10.60 194 259 5.6E-13 T 29-03-2018 CVS48_RS04080 80fd2f75fa27641eed3a7a333ca95c6e 271 SUPERFAMILY SSF46689 205 255 4.48E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS04080 80fd2f75fa27641eed3a7a333ca95c6e 271 Pfam PF02954 Bacterial regulatory protein, Fis family 216 238 4.9E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CVS48_RS06010 e3356efd0496cec613b7bad2a52f658c 341 PIRSF PIRSF015268 1 332 2.8E-129 T 29-03-2018 IPR011204 Virulence protein RhuM-like CVS48_RS06010 e3356efd0496cec613b7bad2a52f658c 341 Pfam PF13310 Virulence protein RhuM family 61 306 2.7E-103 T 29-03-2018 IPR011204 Virulence protein RhuM-like CVS48_RS10015 409400eda60ecc60e31ba7cfd4b421b9 273 Gene3D G3DSA:1.10.3720.10 13 261 2.1E-42 T 29-03-2018 CVS48_RS10015 409400eda60ecc60e31ba7cfd4b421b9 273 SUPERFAMILY SSF161098 13 261 1.4E-51 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS10015 409400eda60ecc60e31ba7cfd4b421b9 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 260 2.4E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS17175 b02d3680819a677fa90dec1511779986 151 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 3 146 2.9E-58 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS17175 b02d3680819a677fa90dec1511779986 151 SUPERFAMILY SSF54637 5 147 3.16E-48 T 29-03-2018 IPR029069 HotDog domain CVS48_RS17175 b02d3680819a677fa90dec1511779986 151 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 3 148 33.927 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS17175 b02d3680819a677fa90dec1511779986 151 Gene3D G3DSA:3.10.129.10 1 151 1.3E-56 T 29-03-2018 CVS48_RS17175 b02d3680819a677fa90dec1511779986 151 Pfam PF07977 FabA-like domain 12 141 3.7E-41 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CVS48_RS25000 47cefcdac117a3bc28b0d11559f997e5 390 Gene3D G3DSA:2.40.160.10 48 390 3.7E-50 T 29-03-2018 CVS48_RS25000 47cefcdac117a3bc28b0d11559f997e5 390 Pfam PF13609 Gram-negative porin 35 357 1.8E-36 T 29-03-2018 CVS48_RS25000 47cefcdac117a3bc28b0d11559f997e5 390 SUPERFAMILY SSF56935 46 390 4.88E-57 T 29-03-2018 CVS48_RS28115 abb90f57bc21b9df76e51da981e63000 314 Gene3D G3DSA:1.10.3720.10 3 301 5.9E-42 T 29-03-2018 CVS48_RS28115 abb90f57bc21b9df76e51da981e63000 314 SUPERFAMILY SSF161098 91 297 1.27E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS28115 abb90f57bc21b9df76e51da981e63000 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 2.1E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS08400 57979f24f5f5c1413c1cbcc34b0bfddd 441 Pfam PF03743 Bacterial conjugation TrbI-like protein 243 433 1.4E-44 T 29-03-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI CVS48_RS04925 bf40ddee42547afb5168d7d815466afb 204 Gene3D G3DSA:3.40.30.10 25 204 1.0E-37 T 29-03-2018 CVS48_RS04925 bf40ddee42547afb5168d7d815466afb 204 Pfam PF02630 SCO1/SenC 44 180 3.8E-45 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS04925 bf40ddee42547afb5168d7d815466afb 204 SUPERFAMILY SSF52833 48 203 1.0E-51 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS18070 c512f4ec4018f4e3c36c15b6ecabf834 402 Gene3D G3DSA:3.40.640.10 46 275 5.8E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS18070 c512f4ec4018f4e3c36c15b6ecabf834 402 SUPERFAMILY SSF53383 5 396 8.02E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS18070 c512f4ec4018f4e3c36c15b6ecabf834 402 Gene3D G3DSA:3.90.1150.10 276 401 4.3E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS18070 c512f4ec4018f4e3c36c15b6ecabf834 402 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CVS48_RS18070 c512f4ec4018f4e3c36c15b6ecabf834 402 Pfam PF00155 Aminotransferase class I and II 36 392 1.5E-62 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS10315 96d2da8a7230411f7b1a742bc73c8bf7 303 SUPERFAMILY SSF46785 50 124 2.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10315 96d2da8a7230411f7b1a742bc73c8bf7 303 Pfam PF09339 IclR helix-turn-helix domain 56 102 6.3E-8 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS10315 96d2da8a7230411f7b1a742bc73c8bf7 303 Gene3D G3DSA:3.30.450.40 124 302 2.0E-34 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS10315 96d2da8a7230411f7b1a742bc73c8bf7 303 Pfam PF01614 Bacterial transcriptional regulator 168 293 2.2E-7 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS10315 96d2da8a7230411f7b1a742bc73c8bf7 303 SMART SM00346 50 140 3.4E-9 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS10315 96d2da8a7230411f7b1a742bc73c8bf7 303 Gene3D G3DSA:1.10.10.10 41 120 3.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS10315 96d2da8a7230411f7b1a742bc73c8bf7 303 SUPERFAMILY SSF55781 117 299 3.4E-29 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS02210 86f48d6d0f812ac5633a4ef633c3d45a 89 Pfam PF05488 PAAR motif 9 78 2.4E-21 T 29-03-2018 IPR008727 PAAR motif CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 Pfam PF12445 Flagellin protein 332 468 2.4E-13 T 29-03-2018 IPR032826 Flagellin, H7-serospecific domain CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 PRINTS PR00207 Flagellin signature 37 54 6.9E-28 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 PRINTS PR00207 Flagellin signature 111 134 6.9E-28 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 PRINTS PR00207 Flagellin signature 76 95 6.9E-28 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.7E-43 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 Gene3D G3DSA:1.20.1330.10 40 535 1.0E-56 T 29-03-2018 CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 Pfam PF00700 Bacterial flagellin C-terminal helical region 477 562 2.8E-29 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 SUPERFAMILY SSF64518 1 183 1.31E-101 T 29-03-2018 CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 SUPERFAMILY SSF64518 212 327 1.31E-101 T 29-03-2018 CVS48_RS16755 e74534afc96ab2cb49d23d164a3b91a9 563 SUPERFAMILY SSF64518 375 563 1.31E-101 T 29-03-2018 CVS48_RS27295 5c30e54e25df9b07ddf42684c1713f38 168 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 19 167 3.3E-61 T 29-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit CVS48_RS27295 5c30e54e25df9b07ddf42684c1713f38 168 SUPERFAMILY SSF117916 6 101 2.03E-27 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CVS48_RS27295 5c30e54e25df9b07ddf42684c1713f38 168 Pfam PF01883 Iron-sulfur cluster assembly protein 10 71 1.5E-13 T 29-03-2018 IPR002744 MIP18 family-like CVS48_RS27295 5c30e54e25df9b07ddf42684c1713f38 168 Gene3D G3DSA:3.30.300.130 6 103 9.6E-24 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CVS48_RS21105 ac441aaa8d23c9ebdcec5e2c7315d656 126 SUPERFAMILY SSF55298 5 125 2.2E-23 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS21105 ac441aaa8d23c9ebdcec5e2c7315d656 126 Pfam PF01042 Endoribonuclease L-PSP 21 124 3.8E-12 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS21105 ac441aaa8d23c9ebdcec5e2c7315d656 126 Gene3D G3DSA:3.30.1330.40 1 126 3.3E-21 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS24870 02f60ebc6026296c857b0ebbdd0ab626 149 PIRSF PIRSF029477 1 148 4.5E-57 T 29-03-2018 IPR016920 Uncharacterised conserved protein UCP029477 CVS48_RS24870 02f60ebc6026296c857b0ebbdd0ab626 149 SUPERFAMILY SSF47240 4 145 2.95E-6 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS24870 02f60ebc6026296c857b0ebbdd0ab626 149 TIGRFAM TIGR02284 TIGR02284: conserved hypothetical protein 6 142 2.0E-46 T 29-03-2018 IPR011971 Conserved hypothetical protein CHP02284 CVS48_RS24870 02f60ebc6026296c857b0ebbdd0ab626 149 Pfam PF09537 Domain of unknown function (DUF2383) 5 114 9.6E-39 T 29-03-2018 IPR019052 Domain of unknown function DUF2383 CVS48_RS24870 02f60ebc6026296c857b0ebbdd0ab626 149 Gene3D G3DSA:1.20.1260.10 1 146 6.9E-27 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS22760 9e4ede73e0abb1da90f6a1c87f634838 195 Pfam PF11319 Type VI secretion system VasI, EvfG, VC_A0118 19 195 4.1E-32 T 29-03-2018 IPR017738 Type VI secretion system-associated, VCA0118 CVS48_RS22760 9e4ede73e0abb1da90f6a1c87f634838 195 TIGRFAM TIGR03360 VI_minor_1: type VI secretion-associated protein, VC_A0118 family 17 195 5.0E-37 T 29-03-2018 IPR017738 Type VI secretion system-associated, VCA0118 CVS48_RS16365 a526fd7ea49f02d559bc419af8861b6a 326 SUPERFAMILY SSF53850 112 283 1.17E-13 T 29-03-2018 CVS48_RS16365 a526fd7ea49f02d559bc419af8861b6a 326 PIRSF PIRSF017082 1 325 3.5E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS16365 a526fd7ea49f02d559bc419af8861b6a 326 Gene3D G3DSA:3.40.190.10 126 240 3.1E-14 T 29-03-2018 CVS48_RS16365 a526fd7ea49f02d559bc419af8861b6a 326 Gene3D G3DSA:3.40.50.720 266 324 0.27 T 29-03-2018 CVS48_RS16365 a526fd7ea49f02d559bc419af8861b6a 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 5.4E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 Pfam PF02040 Arsenical pump membrane protein 3 422 6.4E-152 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 425 1.6E-204 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 4.8E-116 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 4.8E-116 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 4.8E-116 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 4.8E-116 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 4.8E-116 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 4.8E-116 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 4.8E-116 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS26480 dd8726ebfa2eb6139875ffbb68624543 426 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 4.8E-116 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CVS48_RS12755 309a6ae83f39218b025e3ef5d533a843 220 Gene3D G3DSA:3.40.50.2300 1 119 6.2E-36 T 29-03-2018 CVS48_RS12755 309a6ae83f39218b025e3ef5d533a843 220 Pfam PF00072 Response regulator receiver domain 3 113 4.3E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12755 309a6ae83f39218b025e3ef5d533a843 220 SUPERFAMILY SSF52172 1 179 2.28E-40 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS12755 309a6ae83f39218b025e3ef5d533a843 220 SMART SM00862 145 216 1.1E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS12755 309a6ae83f39218b025e3ef5d533a843 220 SMART SM00448 1 112 7.4E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS12755 309a6ae83f39218b025e3ef5d533a843 220 Gene3D G3DSA:1.10.10.10 120 220 6.9E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS12755 309a6ae83f39218b025e3ef5d533a843 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 7.4E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS27670 a77d4535465d75fb0aede500e6822282 188 Pfam PF05233 PHB accumulation regulatory domain 76 114 1.1E-18 T 29-03-2018 IPR007897 PHB accumulation regulatory CVS48_RS27670 a77d4535465d75fb0aede500e6822282 188 Pfam PF05233 PHB accumulation regulatory domain 126 165 1.4E-14 T 29-03-2018 IPR007897 PHB accumulation regulatory CVS48_RS27670 a77d4535465d75fb0aede500e6822282 188 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 12 71 2.2E-31 T 29-03-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal CVS48_RS27670 a77d4535465d75fb0aede500e6822282 188 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 11 117 6.2E-46 T 29-03-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 CVS48_RS23470 427eac59130ad5952218ceea8dfc391b 278 Gene3D G3DSA:2.60.40.10 163 276 9.7E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS08550 b71f3c371a287c185012c02479b3faff 139 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 4 135 4.6E-30 T 29-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein CVS48_RS08550 b71f3c371a287c185012c02479b3faff 139 Pfam PF04965 Gene 25-like lysozyme 28 115 3.1E-16 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD CVS48_RS08550 b71f3c371a287c185012c02479b3faff 139 SUPERFAMILY SSF160719 29 128 2.48E-19 T 29-03-2018 CVS48_RS08550 b71f3c371a287c185012c02479b3faff 139 Gene3D G3DSA:3.10.450.40 9 134 1.9E-21 T 29-03-2018 CVS48_RS25910 63542d75f366ac8c6092c83ebfd071b9 124 SUPERFAMILY SSF55331 2 118 5.5E-23 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CVS48_RS25910 63542d75f366ac8c6092c83ebfd071b9 124 Pfam PF01361 Tautomerase enzyme 64 114 5.8E-9 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CVS48_RS25910 63542d75f366ac8c6092c83ebfd071b9 124 Pfam PF01361 Tautomerase enzyme 2 56 9.5E-12 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CVS48_RS25910 63542d75f366ac8c6092c83ebfd071b9 124 Gene3D G3DSA:3.30.429.10 63 124 1.5E-10 T 29-03-2018 CVS48_RS25910 63542d75f366ac8c6092c83ebfd071b9 124 Gene3D G3DSA:3.30.429.10 1 62 1.9E-14 T 29-03-2018 CVS48_RS25745 1eab2dc2ae3adef1a919151f21fc3833 277 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 265 4.5E-110 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CVS48_RS25745 1eab2dc2ae3adef1a919151f21fc3833 277 Gene3D G3DSA:3.90.550.10 3 277 4.7E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS25745 1eab2dc2ae3adef1a919151f21fc3833 277 SUPERFAMILY SSF53448 3 269 1.04E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS25745 1eab2dc2ae3adef1a919151f21fc3833 277 Pfam PF00483 Nucleotidyl transferase 11 269 1.3E-27 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CVS48_RS07970 2407846038930418f5abd64a701627f6 311 Gene3D G3DSA:3.40.50.150 37 294 4.0E-26 T 29-03-2018 CVS48_RS07970 2407846038930418f5abd64a701627f6 311 SUPERFAMILY SSF53335 39 239 1.1E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS07970 2407846038930418f5abd64a701627f6 311 Pfam PF08241 Methyltransferase domain 58 168 6.6E-15 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CVS48_RS14920 d522df56f417ccbd6418df1234fcf5e6 226 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 70 143 2.9E-8 T 29-03-2018 IPR010319 Transglutaminase-like cysteine peptidase, predicted CVS48_RS17225 a3c9bf2e5610dfc76b5617cf631603cb 245 Pfam PF00117 Glutamine amidotransferase class-I 44 196 2.4E-19 T 29-03-2018 IPR017926 Glutamine amidotransferase CVS48_RS17225 a3c9bf2e5610dfc76b5617cf631603cb 245 Gene3D G3DSA:3.40.50.880 18 242 1.4E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS17225 a3c9bf2e5610dfc76b5617cf631603cb 245 SUPERFAMILY SSF52317 60 242 4.74E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS19550 7c1659706fc9bf04bc034f2b16905819 198 Gene3D G3DSA:3.90.1720.10 53 198 9.6E-44 T 29-03-2018 CVS48_RS19550 7c1659706fc9bf04bc034f2b16905819 198 Pfam PF00877 NlpC/P60 family 75 183 2.6E-34 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CVS48_RS19550 7c1659706fc9bf04bc034f2b16905819 198 SUPERFAMILY SSF54001 56 188 5.56E-44 T 29-03-2018 CVS48_RS18640 2712dc13655c31dd427b1c84b3f3cbd1 318 SUPERFAMILY SSF161098 93 314 5.49E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18640 2712dc13655c31dd427b1c84b3f3cbd1 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 315 1.4E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18640 2712dc13655c31dd427b1c84b3f3cbd1 318 Gene3D G3DSA:1.10.3720.10 4 303 6.1E-43 T 29-03-2018 CVS48_RS01520 723ec1cb5fd331d13eda69ab06c43a80 308 SUPERFAMILY SSF103481 46 148 6.41E-13 T 29-03-2018 CVS48_RS01520 723ec1cb5fd331d13eda69ab06c43a80 308 SUPERFAMILY SSF103481 198 295 5.62E-14 T 29-03-2018 CVS48_RS01520 723ec1cb5fd331d13eda69ab06c43a80 308 Pfam PF00892 EamA-like transporter family 161 291 4.3E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS01520 723ec1cb5fd331d13eda69ab06c43a80 308 Pfam PF00892 EamA-like transporter family 14 146 4.2E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS18340 dd3c5a5d02f301ac9fa11a20c4077cdb 193 Pfam PF13875 Domain of unknown function (DUF4202) 7 182 2.0E-60 T 29-03-2018 IPR025255 Protein of unknown function DUF4202 CVS48_RS17080 b999946b5323efc19b8e55f7dbeb0eb3 162 Pfam PF02674 Colicin V production protein 4 142 2.3E-35 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CVS48_RS06200 f01d5d81005e355df355818d616cad38 337 PIRSF PIRSF017082 3 337 1.3E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS06200 f01d5d81005e355df355818d616cad38 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 333 1.8E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS06200 f01d5d81005e355df355818d616cad38 337 SUPERFAMILY SSF53850 127 295 1.86E-13 T 29-03-2018 CVS48_RS06200 f01d5d81005e355df355818d616cad38 337 Gene3D G3DSA:3.40.190.10 136 243 4.0E-15 T 29-03-2018 CVS48_RS00295 8e4b653235e616b6f2c90d6dec8cdc91 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 8 29 1.1E-10 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CVS48_RS00295 8e4b653235e616b6f2c90d6dec8cdc91 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 29 1.2E-9 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CVS48_RS23280 5a5ef1734ea78d71286a349ef1b908d7 133 Pfam PF00486 Transcriptional regulatory protein, C terminal 54 123 2.3E-10 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS23280 5a5ef1734ea78d71286a349ef1b908d7 133 Gene3D G3DSA:1.10.10.10 34 126 4.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23280 5a5ef1734ea78d71286a349ef1b908d7 133 SUPERFAMILY SSF46894 46 124 9.64E-14 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS23280 5a5ef1734ea78d71286a349ef1b908d7 133 SMART SM00862 52 123 7.7E-11 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS02280 a1cf5cc97c91ef61ab90b068d15286b5 146 Pfam PF01475 Ferric uptake regulator family 9 128 2.3E-37 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CVS48_RS02280 a1cf5cc97c91ef61ab90b068d15286b5 146 SUPERFAMILY SSF46785 4 132 3.16E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02280 a1cf5cc97c91ef61ab90b068d15286b5 146 Gene3D G3DSA:1.10.10.10 2 88 4.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19305 556f2a7c0bd40c4c36ce47f84f6bbd55 437 Pfam PF13416 Bacterial extracellular solute-binding protein 45 361 5.8E-50 T 29-03-2018 CVS48_RS19305 556f2a7c0bd40c4c36ce47f84f6bbd55 437 Gene3D G3DSA:3.40.190.10 25 216 1.2E-35 T 29-03-2018 CVS48_RS19305 556f2a7c0bd40c4c36ce47f84f6bbd55 437 Gene3D G3DSA:3.40.190.10 230 379 1.2E-11 T 29-03-2018 CVS48_RS19305 556f2a7c0bd40c4c36ce47f84f6bbd55 437 SUPERFAMILY SSF53850 22 426 1.94E-79 T 29-03-2018 CVS48_RS19305 556f2a7c0bd40c4c36ce47f84f6bbd55 437 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 141 158 - T 29-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 CVS48_RS23870 c3d71ca12c72f7fa6759a44543d5a53a 181 Gene3D G3DSA:3.10.129.10 5 167 5.4E-21 T 29-03-2018 CVS48_RS23870 c3d71ca12c72f7fa6759a44543d5a53a 181 Pfam PF14539 Domain of unknown function (DUF4442) 20 155 1.1E-15 T 29-03-2018 IPR027961 Protein of unknown function DUF4442 CVS48_RS23870 c3d71ca12c72f7fa6759a44543d5a53a 181 SUPERFAMILY SSF54637 11 155 1.22E-20 T 29-03-2018 IPR029069 HotDog domain CVS48_RS06715 31e22b5a7041db959239363e74bfc50c 444 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 5 443 2.6E-151 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 CVS48_RS06715 31e22b5a7041db959239363e74bfc50c 444 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 442 1.7E-161 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 Gene3D G3DSA:3.50.50.60 5 397 2.6E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 SUPERFAMILY SSF51905 283 371 6.83E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 SUPERFAMILY SSF51905 18 186 6.83E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 1.3E-20 T 29-03-2018 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 165 180 1.3E-20 T 29-03-2018 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 1.3E-20 T 29-03-2018 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 1.3E-20 T 29-03-2018 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 345 361 1.3E-20 T 29-03-2018 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 Pfam PF01494 FAD binding domain 18 356 1.5E-25 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS09390 eaab0046f642e3e0339144dfc10e8be9 408 SUPERFAMILY SSF54373 190 289 2.59E-13 T 29-03-2018 CVS48_RS02380 15aa0237534ed10e7de251b128f96002 184 Pfam PF07017 Antimicrobial peptide resistance and lipid A acylation protein PagP 37 181 5.6E-62 T 29-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 CVS48_RS02380 15aa0237534ed10e7de251b128f96002 184 Gene3D G3DSA:2.40.160.20 29 184 1.8E-52 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CVS48_RS02380 15aa0237534ed10e7de251b128f96002 184 ProDom PD103779 CRCA ANTIMICROBIAL RESISTANCE LIPOPROTEIN RCP A PEPTIDE ACYLATION LIPID EXPORTED 36 171 2.0E-59 T 29-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 CVS48_RS02380 15aa0237534ed10e7de251b128f96002 184 SUPERFAMILY SSF56925 27 184 8.63E-68 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CVS48_RS02380 15aa0237534ed10e7de251b128f96002 184 Hamap MF_00837 Lipid A palmitoyltransferase PagP [pagP]. 1 184 37.123 T 29-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 CVS48_RS15195 03b8d45eda8b28653eb766a648fc6386 147 SMART SM00422 19 89 3.3E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS15195 03b8d45eda8b28653eb766a648fc6386 147 Pfam PF13411 MerR HTH family regulatory protein 19 85 2.6E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CVS48_RS15195 03b8d45eda8b28653eb766a648fc6386 147 Gene3D G3DSA:1.10.1660.10 14 140 1.3E-27 T 29-03-2018 CVS48_RS15195 03b8d45eda8b28653eb766a648fc6386 147 SUPERFAMILY SSF46955 17 120 2.61E-19 T 29-03-2018 IPR009061 Putative DNA-binding domain CVS48_RS26235 582065ec496f7dfa364fd750ebb08b76 118 Pfam PF03960 ArsC family 46 114 1.0E-13 T 29-03-2018 IPR006660 Arsenate reductase-like CVS48_RS26235 582065ec496f7dfa364fd750ebb08b76 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 5 114 8.0E-28 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CVS48_RS26235 582065ec496f7dfa364fd750ebb08b76 118 Gene3D G3DSA:3.40.30.10 1 117 2.3E-33 T 29-03-2018 CVS48_RS26235 582065ec496f7dfa364fd750ebb08b76 118 SUPERFAMILY SSF52833 4 116 7.11E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS16815 4b68c3689cb42d317221bb3479c740ea 129 Gene3D G3DSA:3.40.50.2300 1 128 4.4E-37 T 29-03-2018 CVS48_RS16815 4b68c3689cb42d317221bb3479c740ea 129 SMART SM00448 6 120 1.5E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS16815 4b68c3689cb42d317221bb3479c740ea 129 Pfam PF00072 Response regulator receiver domain 8 120 1.0E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS16815 4b68c3689cb42d317221bb3479c740ea 129 SUPERFAMILY SSF52172 4 125 8.97E-37 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS21540 dda647ce0cdc930579699ea47bee7474 272 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 151 171 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CVS48_RS21540 dda647ce0cdc930579699ea47bee7474 272 Gene3D G3DSA:3.60.110.10 1 271 3.7E-73 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS21540 dda647ce0cdc930579699ea47bee7474 272 SUPERFAMILY SSF56317 1 268 3.14E-77 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS21540 dda647ce0cdc930579699ea47bee7474 272 Pfam PF00795 Carbon-nitrogen hydrolase 2 260 1.0E-51 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS22100 a86af42eb8f4401fd35545d5bbd2e2e2 522 Pfam PF01565 FAD binding domain 97 235 3.7E-31 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CVS48_RS22100 a86af42eb8f4401fd35545d5bbd2e2e2 522 Pfam PF02913 FAD linked oxidases, C-terminal domain 272 509 3.9E-27 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CVS48_RS22100 a86af42eb8f4401fd35545d5bbd2e2e2 522 Gene3D G3DSA:1.10.45.10 471 509 1.9E-11 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CVS48_RS22100 a86af42eb8f4401fd35545d5bbd2e2e2 522 SUPERFAMILY SSF56176 54 272 2.8E-47 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CVS48_RS22100 a86af42eb8f4401fd35545d5bbd2e2e2 522 SUPERFAMILY SSF55103 249 512 1.83E-33 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CVS48_RS22100 a86af42eb8f4401fd35545d5bbd2e2e2 522 Gene3D G3DSA:3.30.465.10 149 291 4.0E-31 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CVS48_RS22100 a86af42eb8f4401fd35545d5bbd2e2e2 522 Gene3D G3DSA:3.30.43.10 39 148 9.3E-17 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CVS48_RS24270 19b6b22eb0c96da37ea88feb06ad01bc 169 Gene3D G3DSA:1.10.10.60 54 98 1.1E-7 T 29-03-2018 CVS48_RS24270 19b6b22eb0c96da37ea88feb06ad01bc 169 Pfam PF01381 Helix-turn-helix 82 132 6.0E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS24270 19b6b22eb0c96da37ea88feb06ad01bc 169 SMART SM00530 78 134 9.8E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS24270 19b6b22eb0c96da37ea88feb06ad01bc 169 SUPERFAMILY SSF47413 81 136 5.36E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS24270 19b6b22eb0c96da37ea88feb06ad01bc 169 Gene3D G3DSA:3.30.1190.10 99 165 1.7E-8 T 29-03-2018 CVS48_RS19440 b9e5194d423652e492b136bc8f57d474 347 Pfam PF13343 Bacterial extracellular solute-binding protein 79 305 3.6E-18 T 29-03-2018 CVS48_RS19440 b9e5194d423652e492b136bc8f57d474 347 PIRSF PIRSF002825 5 347 7.7E-87 T 29-03-2018 IPR026045 Ferric binding protein CVS48_RS19440 b9e5194d423652e492b136bc8f57d474 347 Gene3D G3DSA:3.40.190.10 29 168 1.9E-20 T 29-03-2018 CVS48_RS19440 b9e5194d423652e492b136bc8f57d474 347 SUPERFAMILY SSF53850 30 344 3.26E-74 T 29-03-2018 CVS48_RS19440 b9e5194d423652e492b136bc8f57d474 347 Gene3D G3DSA:3.40.190.10 169 314 1.7E-18 T 29-03-2018 CVS48_RS25425 8fdb418972c44306405a908e55578f63 165 Gene3D G3DSA:3.40.50.720 20 165 6.4E-4 T 29-03-2018 CVS48_RS26635 18018204cf565cc1bef49dd260e0e3f1 479 SUPERFAMILY SSF52467 306 479 3.0E-75 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS26635 18018204cf565cc1bef49dd260e0e3f1 479 PIRSF PIRSF000204 2 479 8.2E-212 T 29-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 CVS48_RS26635 18018204cf565cc1bef49dd260e0e3f1 479 Gene3D G3DSA:3.40.50.1220 305 479 2.0E-83 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CVS48_RS26635 18018204cf565cc1bef49dd260e0e3f1 479 Pfam PF02233 NAD(P) transhydrogenase beta subunit 8 476 1.4E-191 T 29-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CVS48_RS12740 a95dddddcb53c5d2f60b8e490b33272d 443 SUPERFAMILY SSF50952 132 441 1.7E-36 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CVS48_RS12740 a95dddddcb53c5d2f60b8e490b33272d 443 SUPERFAMILY SSF50952 62 101 1.7E-36 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CVS48_RS12740 a95dddddcb53c5d2f60b8e490b33272d 443 Gene3D G3DSA:2.120.10.30 332 443 5.9E-12 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS12740 a95dddddcb53c5d2f60b8e490b33272d 443 Gene3D G3DSA:2.120.10.30 59 331 8.5E-35 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CVS48_RS12740 a95dddddcb53c5d2f60b8e490b33272d 443 Pfam PF07995 Glucose / Sorbosone dehydrogenase 176 328 1.1E-10 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CVS48_RS07715 72d91996c115d901c38c23912043453f 320 SUPERFAMILY SSF50685 86 170 1.22E-6 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CVS48_RS07715 72d91996c115d901c38c23912043453f 320 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 89 181 2.0E-38 T 29-03-2018 IPR012997 Rare lipoprotein A CVS48_RS07715 72d91996c115d901c38c23912043453f 320 Gene3D G3DSA:2.40.40.10 69 179 9.2E-23 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CVS48_RS07715 72d91996c115d901c38c23912043453f 320 Pfam PF05036 Sporulation related domain 244 307 2.1E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS07715 72d91996c115d901c38c23912043453f 320 Pfam PF03330 Lytic transglycolase 87 174 3.6E-23 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CVS48_RS07715 72d91996c115d901c38c23912043453f 320 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 23 179 23.44 T 29-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 CVS48_RS07715 72d91996c115d901c38c23912043453f 320 Gene3D G3DSA:3.30.70.1070 240 310 8.5E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS07715 72d91996c115d901c38c23912043453f 320 SUPERFAMILY SSF110997 245 307 1.83E-11 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS08990 bf0fd9dfb4119ee4356ca0ff8975d6b5 214 PIRSF PIRSF006324 1 209 1.7E-45 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS08990 bf0fd9dfb4119ee4356ca0ff8975d6b5 214 Pfam PF01810 LysE type translocator 16 207 3.5E-29 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS26795 59d7655a8cee29b9ae74c169971d0303 266 Gene3D G3DSA:3.40.50.10090 153 260 7.3E-16 T 29-03-2018 CVS48_RS26795 59d7655a8cee29b9ae74c169971d0303 266 SUPERFAMILY SSF69618 7 238 6.54E-32 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS26795 59d7655a8cee29b9ae74c169971d0303 266 Gene3D G3DSA:3.40.50.10090 40 152 1.4E-22 T 29-03-2018 CVS48_RS26795 59d7655a8cee29b9ae74c169971d0303 266 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 235 4.4E-24 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CVS48_RS17040 db4f75bbb4be8065733858f50ab96900 125 Pfam PF03646 FlaG protein 35 119 5.7E-22 T 29-03-2018 IPR005186 FlaG protein CVS48_RS17040 db4f75bbb4be8065733858f50ab96900 125 SUPERFAMILY SSF160214 22 121 7.59E-23 T 29-03-2018 IPR005186 FlaG protein CVS48_RS17040 db4f75bbb4be8065733858f50ab96900 125 Gene3D G3DSA:3.30.160.170 25 121 1.3E-21 T 29-03-2018 IPR005186 FlaG protein CVS48_RS13850 50345c6820493aa2474b929307b3eaf9 210 SUPERFAMILY SSF53335 27 209 1.37E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS13850 50345c6820493aa2474b929307b3eaf9 210 PIRSF PIRSF005461 1 210 6.1E-69 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 CVS48_RS13850 50345c6820493aa2474b929307b3eaf9 210 Pfam PF01728 FtsJ-like methyltransferase 28 208 6.8E-53 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CVS48_RS13850 50345c6820493aa2474b929307b3eaf9 210 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 210 30.377 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 CVS48_RS13850 50345c6820493aa2474b929307b3eaf9 210 Gene3D G3DSA:3.40.50.150 1 210 1.8E-48 T 29-03-2018 CVS48_RS22720 b56c4420c0224139a2a0a5a9c2bda850 400 SUPERFAMILY SSF53474 178 260 4.69E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS22720 b56c4420c0224139a2a0a5a9c2bda850 400 SUPERFAMILY SSF53474 99 148 4.69E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS22720 b56c4420c0224139a2a0a5a9c2bda850 400 Gene3D G3DSA:3.40.50.1820 58 381 2.1E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS00325 de7d95d38bbd8ba96188176fbc7fd777 255 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 29 255 1.5E-74 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 CVS48_RS00325 de7d95d38bbd8ba96188176fbc7fd777 255 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 10 255 1.3E-69 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 CVS48_RS02645 e0d483b6d3232ffd0d19a1c0ab890194 509 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 22 441 7.3E-133 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CVS48_RS09555 03480cfc217b80d3139a0f23e9b467d9 79 Pfam PF12167 Arm DNA-binding domain 7 67 5.9E-17 T 29-03-2018 IPR022000 Min27-like integrase, DNA-binding domain CVS48_RS10775 9b1753b4a0ffd9c49af4975ebef339b7 282 Gene3D G3DSA:3.40.50.720 13 239 2.2E-33 T 29-03-2018 CVS48_RS10775 9b1753b4a0ffd9c49af4975ebef339b7 282 Pfam PF01370 NAD dependent epimerase/dehydratase family 18 178 4.3E-21 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS10775 9b1753b4a0ffd9c49af4975ebef339b7 282 SUPERFAMILY SSF51735 16 238 4.44E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS17375 8dbabae419e43bcb85c5cddba2fe7354 302 SUPERFAMILY SSF103481 189 287 4.84E-13 T 29-03-2018 CVS48_RS17375 8dbabae419e43bcb85c5cddba2fe7354 302 Pfam PF00892 EamA-like transporter family 13 140 6.3E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS17375 8dbabae419e43bcb85c5cddba2fe7354 302 Pfam PF00892 EamA-like transporter family 154 284 5.3E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS17375 8dbabae419e43bcb85c5cddba2fe7354 302 SUPERFAMILY SSF103481 40 141 1.57E-13 T 29-03-2018 CVS48_RS22565 b94bb7b25d068a786f05685f3e96f628 288 Pfam PF01925 Sulfite exporter TauE/SafE 10 282 1.9E-50 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CVS48_RS22565 b94bb7b25d068a786f05685f3e96f628 288 SUPERFAMILY SSF103473 10 214 4.19E-6 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS22565 b94bb7b25d068a786f05685f3e96f628 288 SUPERFAMILY SSF103473 241 286 4.19E-6 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS08670 2b21897d873d7659d5566e43bdf08a99 221 SUPERFAMILY SSF88659 155 215 1.77E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS08670 2b21897d873d7659d5566e43bdf08a99 221 Gene3D G3DSA:1.10.10.10 108 218 5.8E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS08670 2b21897d873d7659d5566e43bdf08a99 221 Pfam PF08281 Sigma-70, region 4 161 210 6.9E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS19135 ff9802799be3a128df9e578c26fae40a 412 Pfam PF01266 FAD dependent oxidoreductase 4 395 3.2E-62 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS19135 ff9802799be3a128df9e578c26fae40a 412 SUPERFAMILY SSF54373 271 356 2.0E-6 T 29-03-2018 CVS48_RS19135 ff9802799be3a128df9e578c26fae40a 412 SUPERFAMILY SSF51905 3 57 3.63E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19135 ff9802799be3a128df9e578c26fae40a 412 SUPERFAMILY SSF51905 108 268 3.63E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19135 ff9802799be3a128df9e578c26fae40a 412 SUPERFAMILY SSF51905 356 412 3.63E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS19135 ff9802799be3a128df9e578c26fae40a 412 Gene3D G3DSA:3.50.50.60 1 412 1.4E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00680 6d6bf7c9e8c12039f0e3ac849052462e 230 TIGRFAM TIGR03746 conj_TIGR03746: integrating conjugative element protein, PFL_4703 family 4 207 5.9E-96 T 29-03-2018 IPR021548 Protein of unknown function DUF2895 CVS48_RS00680 6d6bf7c9e8c12039f0e3ac849052462e 230 Pfam PF11444 Protein of unknown function (DUF2895) 6 206 1.8E-90 T 29-03-2018 IPR021548 Protein of unknown function DUF2895 CVS48_RS10835 bc6219fef88239a683ac91d644baf6c0 200 SUPERFAMILY SSF89392 29 199 3.14E-30 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CVS48_RS10835 bc6219fef88239a683ac91d644baf6c0 200 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 13 200 20.1 T 29-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 CVS48_RS10835 bc6219fef88239a683ac91d644baf6c0 200 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 61 175 1.2E-22 T 29-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 CVS48_RS10835 bc6219fef88239a683ac91d644baf6c0 200 Gene3D G3DSA:2.50.20.10 37 199 5.3E-30 T 29-03-2018 CVS48_RS10835 bc6219fef88239a683ac91d644baf6c0 200 Pfam PF03550 Outer membrane lipoprotein LolB 44 199 2.3E-34 T 29-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 CVS48_RS17845 145251be63c6bbe23a484f79b5836021 333 PIRSF PIRSF017082 2 333 9.8E-97 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS17845 145251be63c6bbe23a484f79b5836021 333 SUPERFAMILY SSF53850 110 299 3.26E-11 T 29-03-2018 CVS48_RS17845 145251be63c6bbe23a484f79b5836021 333 Gene3D G3DSA:3.40.190.10 140 304 7.4E-14 T 29-03-2018 CVS48_RS17845 145251be63c6bbe23a484f79b5836021 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 321 1.5E-49 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS00080 ee12b4ca0b91724aa11eb8f6314373cc 769 Pfam PF13515 Fusaric acid resistance protein-like 419 543 8.5E-17 T 29-03-2018 CVS48_RS00080 ee12b4ca0b91724aa11eb8f6314373cc 769 Pfam PF12805 FUSC-like inner membrane protein yccS 72 352 9.4E-70 T 29-03-2018 IPR032692 Integral membrane protein YccS, N-terminal CVS48_RS09935 eb228b8145dce9fd50ef3f50ced78ee2 137 Gene3D G3DSA:1.10.10.10 2 43 3.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09935 eb228b8145dce9fd50ef3f50ced78ee2 137 Pfam PF13560 Helix-turn-helix domain 25 84 2.5E-7 T 29-03-2018 CVS48_RS09935 eb228b8145dce9fd50ef3f50ced78ee2 137 SUPERFAMILY SSF47413 24 84 2.08E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS09935 eb228b8145dce9fd50ef3f50ced78ee2 137 Gene3D G3DSA:1.10.260.40 44 102 9.0E-9 T 29-03-2018 CVS48_RS06145 117402912f0228e8b4ba9da742b285e5 68 SUPERFAMILY SSF50249 3 67 1.03E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS06145 117402912f0228e8b4ba9da742b285e5 68 PIRSF PIRSF002599 1 68 9.0E-26 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CVS48_RS06145 117402912f0228e8b4ba9da742b285e5 68 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 2.2E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS06145 117402912f0228e8b4ba9da742b285e5 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 29-03-2018 IPR019844 Cold-shock conserved site CVS48_RS06145 117402912f0228e8b4ba9da742b285e5 68 SMART SM00357 4 68 2.3E-30 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CVS48_RS06145 117402912f0228e8b4ba9da742b285e5 68 PRINTS PR00050 Cold shock protein signature 41 59 1.2E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS06145 117402912f0228e8b4ba9da742b285e5 68 PRINTS PR00050 Cold shock protein signature 5 20 1.2E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS06145 117402912f0228e8b4ba9da742b285e5 68 PRINTS PR00050 Cold shock protein signature 26 35 1.2E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CVS48_RS06145 117402912f0228e8b4ba9da742b285e5 68 Gene3D G3DSA:2.40.50.140 1 68 2.8E-28 T 29-03-2018 CVS48_RS11715 7f16f8861c8f54a2282c989b8f99f06d 688 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 146 1.1E-24 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS11715 7f16f8861c8f54a2282c989b8f99f06d 688 Gene3D G3DSA:2.170.130.10 6 158 1.5E-29 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS11715 7f16f8861c8f54a2282c989b8f99f06d 688 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 45 688 3.5E-87 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS11715 7f16f8861c8f54a2282c989b8f99f06d 688 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 671 688 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CVS48_RS11715 7f16f8861c8f54a2282c989b8f99f06d 688 SUPERFAMILY SSF56935 12 688 8.01E-130 T 29-03-2018 CVS48_RS11715 7f16f8861c8f54a2282c989b8f99f06d 688 Pfam PF00593 TonB dependent receptor 232 687 9.0E-52 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS11715 7f16f8861c8f54a2282c989b8f99f06d 688 Gene3D G3DSA:2.40.170.20 160 688 1.6E-75 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS11890 c13f40c952458af24ecdcd9cee8a5a0a 193 SMART SM00867 25 190 9.1E-55 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CVS48_RS11890 c13f40c952458af24ecdcd9cee8a5a0a 193 Pfam PF04264 YceI-like domain 26 189 1.7E-34 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CVS48_RS11890 c13f40c952458af24ecdcd9cee8a5a0a 193 SUPERFAMILY SSF101874 23 191 4.71E-46 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CVS48_RS11890 c13f40c952458af24ecdcd9cee8a5a0a 193 Gene3D G3DSA:2.40.128.110 24 191 2.6E-43 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CVS48_RS15845 52daf023b4035a816fdcad268a3675da 152 Pfam PF00293 NUDIX domain 19 128 3.8E-21 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CVS48_RS15845 52daf023b4035a816fdcad268a3675da 152 SUPERFAMILY SSF55811 14 132 2.17E-32 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS15845 52daf023b4035a816fdcad268a3675da 152 Gene3D G3DSA:3.90.79.10 10 149 3.2E-30 T 29-03-2018 CVS48_RS15845 52daf023b4035a816fdcad268a3675da 152 PRINTS PR00502 NUDIX hydrolase family signature 57 72 2.3E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CVS48_RS15845 52daf023b4035a816fdcad268a3675da 152 PRINTS PR00502 NUDIX hydrolase family signature 43 57 2.3E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CVS48_RS06660 96496269a4df79d0e4d13e40465f073d 500 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 69 493 1.2E-189 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CVS48_RS06660 96496269a4df79d0e4d13e40465f073d 500 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 19 493 4.3E-222 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CVS48_RS05645 d64968672466078c835395401bad0dbf 96 Pfam PF13023 HD domain 16 55 8.5E-9 T 29-03-2018 IPR006674 HD domain CVS48_RS05645 d64968672466078c835395401bad0dbf 96 SUPERFAMILY SSF109604 6 53 1.81E-12 T 29-03-2018 CVS48_RS05645 d64968672466078c835395401bad0dbf 96 Gene3D G3DSA:1.10.3210.10 1 65 3.6E-13 T 29-03-2018 CVS48_RS18895 5b13170a523c478e14991ff9307701dd 397 SUPERFAMILY SSF103473 17 391 1.05E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS18895 5b13170a523c478e14991ff9307701dd 397 Gene3D G3DSA:1.20.1250.20 14 197 1.7E-11 T 29-03-2018 CVS48_RS18895 5b13170a523c478e14991ff9307701dd 397 Pfam PF07690 Major Facilitator Superfamily 41 354 1.7E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS18895 5b13170a523c478e14991ff9307701dd 397 Gene3D G3DSA:1.20.1250.20 209 392 2.0E-19 T 29-03-2018 CVS48_RS10495 dbe3629bec87b872102a43c08d1beb45 244 Pfam PF00581 Rhodanese-like domain 119 214 5.2E-6 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS10495 dbe3629bec87b872102a43c08d1beb45 244 SUPERFAMILY SSF52821 99 235 6.81E-25 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS10495 dbe3629bec87b872102a43c08d1beb45 244 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 243 32.345 T 29-03-2018 IPR020936 Uncharacterised protein family UPF0176 CVS48_RS10495 dbe3629bec87b872102a43c08d1beb45 244 Gene3D G3DSA:3.40.250.10 107 226 7.7E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS10495 dbe3629bec87b872102a43c08d1beb45 244 SMART SM00450 119 220 3.8E-8 T 29-03-2018 IPR001763 Rhodanese-like domain CVS48_RS24250 14cb273ff22eb0dfb07d266d72241c24 72 Pfam PF11755 Protein of unknown function (DUF3311) 10 65 3.7E-12 T 29-03-2018 IPR021741 Protein of unknown function DUF3311 CVS48_RS15705 476492016d8599ccc2b37577cb55f091 463 Gene3D G3DSA:1.25.40.10 229 308 8.2E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS15705 476492016d8599ccc2b37577cb55f091 463 SMART SM00028 257 290 24.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS15705 476492016d8599ccc2b37577cb55f091 463 SMART SM00028 186 219 1.0E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS15705 476492016d8599ccc2b37577cb55f091 463 SUPERFAMILY SSF48452 181 310 4.6E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS15705 476492016d8599ccc2b37577cb55f091 463 Gene3D G3DSA:1.25.40.10 168 228 4.8E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS15705 476492016d8599ccc2b37577cb55f091 463 Pfam PF07719 Tetratricopeptide repeat 186 218 4.7E-7 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 CVS48_RS15705 476492016d8599ccc2b37577cb55f091 463 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 4 120 5.7E-26 T 29-03-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI CVS48_RS24360 122f0e008fe262b1257d45dab226b491 477 Gene3D G3DSA:1.10.287.1060 3 68 1.9E-4 T 29-03-2018 CVS48_RS24360 122f0e008fe262b1257d45dab226b491 477 SUPERFAMILY SSF88874 254 353 3.14E-11 T 29-03-2018 CVS48_RS24360 122f0e008fe262b1257d45dab226b491 477 SUPERFAMILY SSF88874 186 227 3.14E-11 T 29-03-2018 CVS48_RS24360 122f0e008fe262b1257d45dab226b491 477 Gene3D G3DSA:4.10.1070.10 261 331 0.0013 T 29-03-2018 CVS48_RS24360 122f0e008fe262b1257d45dab226b491 477 Gene3D G3DSA:3.90.1340.10 186 260 8.7E-15 T 29-03-2018 IPR011083 Phage tail collar domain CVS48_RS15625 deff2f1db59a13570e1b052b47e56a6c 294 SUPERFAMILY SSF103481 185 287 1.57E-9 T 29-03-2018 CVS48_RS15625 deff2f1db59a13570e1b052b47e56a6c 294 SUPERFAMILY SSF103481 39 135 2.62E-15 T 29-03-2018 CVS48_RS15625 deff2f1db59a13570e1b052b47e56a6c 294 Pfam PF00892 EamA-like transporter family 150 286 4.0E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS15625 deff2f1db59a13570e1b052b47e56a6c 294 Pfam PF00892 EamA-like transporter family 7 133 3.7E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS04900 3e6f7de8c8cea1754e654b6e6c685c5e 456 SUPERFAMILY SSF103473 9 205 1.7E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS04900 3e6f7de8c8cea1754e654b6e6c685c5e 456 SUPERFAMILY SSF103473 252 450 1.7E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS04900 3e6f7de8c8cea1754e654b6e6c685c5e 456 Gene3D G3DSA:1.20.1250.20 15 207 9.8E-26 T 29-03-2018 CVS48_RS04900 3e6f7de8c8cea1754e654b6e6c685c5e 456 Pfam PF07690 Major Facilitator Superfamily 29 413 6.4E-49 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS04900 3e6f7de8c8cea1754e654b6e6c685c5e 456 Gene3D G3DSA:1.20.1250.20 263 453 1.4E-26 T 29-03-2018 CVS48_RS25140 710c5e6bb60dd04514f69be42fc07dfd 283 SUPERFAMILY SSF55781 73 248 8.5E-33 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS25140 710c5e6bb60dd04514f69be42fc07dfd 283 SMART SM00346 2 92 8.4E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS25140 710c5e6bb60dd04514f69be42fc07dfd 283 Pfam PF09339 IclR helix-turn-helix domain 4 55 7.8E-9 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS25140 710c5e6bb60dd04514f69be42fc07dfd 283 SUPERFAMILY SSF46785 4 74 2.45E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25140 710c5e6bb60dd04514f69be42fc07dfd 283 Gene3D G3DSA:1.10.10.10 1 71 2.2E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25140 710c5e6bb60dd04514f69be42fc07dfd 283 Pfam PF01614 Bacterial transcriptional regulator 127 247 3.3E-14 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS25140 710c5e6bb60dd04514f69be42fc07dfd 283 Gene3D G3DSA:3.30.450.40 72 254 4.3E-34 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS04680 0f4d54c9aa6ee670ff5763c9cc981ce2 427 Gene3D G3DSA:3.40.50.10540 5 427 1.0E-117 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS04680 0f4d54c9aa6ee670ff5763c9cc981ce2 427 Pfam PF02515 CoA-transferase family III 11 355 5.3E-106 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS04680 0f4d54c9aa6ee670ff5763c9cc981ce2 427 SUPERFAMILY SSF89796 9 359 2.88E-102 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS04680 0f4d54c9aa6ee670ff5763c9cc981ce2 427 SUPERFAMILY SSF89796 389 426 2.27E-5 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS09245 5e83cd2ab2af414d974d35da4c6b9d5a 181 SUPERFAMILY SSF55729 10 173 1.08E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS09245 5e83cd2ab2af414d974d35da4c6b9d5a 181 Gene3D G3DSA:3.40.630.30 5 180 5.8E-35 T 29-03-2018 CVS48_RS09245 5e83cd2ab2af414d974d35da4c6b9d5a 181 Pfam PF13420 Acetyltransferase (GNAT) domain 10 164 6.0E-20 T 29-03-2018 CVS48_RS10585 4fb8b4ed9ebcba41238d022c0d2c5efe 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 35.934 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CVS48_RS10585 4fb8b4ed9ebcba41238d022c0d2c5efe 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CVS48_RS10585 4fb8b4ed9ebcba41238d022c0d2c5efe 125 Gene3D G3DSA:2.40.50.100 5 125 2.6E-40 T 29-03-2018 CVS48_RS10585 4fb8b4ed9ebcba41238d022c0d2c5efe 125 Pfam PF01597 Glycine cleavage H-protein 7 122 5.7E-39 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CVS48_RS10585 4fb8b4ed9ebcba41238d022c0d2c5efe 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 123 1.5E-39 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CVS48_RS10585 4fb8b4ed9ebcba41238d022c0d2c5efe 125 SUPERFAMILY SSF51230 3 123 6.81E-39 T 29-03-2018 IPR011053 Single hybrid motif CVS48_RS13665 48579e9e6e3cf62518610b53c6a039a7 93 SUPERFAMILY SSF143120 6 79 8.63E-17 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CVS48_RS13665 48579e9e6e3cf62518610b53c6a039a7 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 60 5.5E-7 T 29-03-2018 CVS48_RS13665 48579e9e6e3cf62518610b53c6a039a7 93 Gene3D G3DSA:3.40.1620.10 6 64 3.8E-9 T 29-03-2018 CVS48_RS13665 48579e9e6e3cf62518610b53c6a039a7 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 75 7.9E-16 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CVS48_RS16070 0c6a165b74546b73c6d38e404e8db6be 410 Pfam PF12573 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal 6 44 9.6E-19 T 29-03-2018 IPR022593 2-oxoisovalerate dehydrogenase, E1 alpha subunit, N-terminal domain KEGG: 00280+1.2.4.4|KEGG: 00640+1.2.4.4|MetaCyc: PWY-5046 CVS48_RS16070 0c6a165b74546b73c6d38e404e8db6be 410 SUPERFAMILY SSF52518 47 407 1.59E-93 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS16070 0c6a165b74546b73c6d38e404e8db6be 410 Gene3D G3DSA:3.40.50.970 2 408 1.7E-86 T 29-03-2018 CVS48_RS16070 0c6a165b74546b73c6d38e404e8db6be 410 Pfam PF00676 Dehydrogenase E1 component 81 377 5.8E-99 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CVS48_RS11080 f72532b26f5fdf45ff1a2902783bc640 220 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 75 204 5.7E-30 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS16650 1963baa3edf4443002fc98a99e851724 204 Gene3D G3DSA:3.40.30.10 33 200 6.7E-33 T 29-03-2018 CVS48_RS16650 1963baa3edf4443002fc98a99e851724 204 Pfam PF02630 SCO1/SenC 43 178 1.1E-37 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS16650 1963baa3edf4443002fc98a99e851724 204 SUPERFAMILY SSF52833 44 201 5.46E-45 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS14160 dddeb95e0169a15c1ba67c7368a01547 356 Gene3D G3DSA:3.40.50.1970 1 161 4.8E-25 T 29-03-2018 CVS48_RS14160 dddeb95e0169a15c1ba67c7368a01547 356 PIRSF PIRSF000112 1 352 7.9E-65 T 29-03-2018 CVS48_RS14160 dddeb95e0169a15c1ba67c7368a01547 356 SUPERFAMILY SSF56796 2 354 3.93E-67 T 29-03-2018 CVS48_RS14160 dddeb95e0169a15c1ba67c7368a01547 356 Gene3D G3DSA:1.20.1090.10 162 356 8.7E-26 T 29-03-2018 CVS48_RS14160 dddeb95e0169a15c1ba67c7368a01547 356 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 346 1.3E-51 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CVS48_RS27605 5eab78f92d469cdcad167c11947c297d 376 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 12 373 2.6E-152 T 29-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition CVS48_RS27605 5eab78f92d469cdcad167c11947c297d 376 SUPERFAMILY SSF55729 176 347 1.59E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS27605 5eab78f92d469cdcad167c11947c297d 376 Gene3D G3DSA:3.40.630.30 176 332 4.7E-36 T 29-03-2018 CVS48_RS27605 5eab78f92d469cdcad167c11947c297d 376 Gene3D G3DSA:3.40.630.30 10 175 2.0E-19 T 29-03-2018 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 77 248 2.8E-46 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 362 443 2.3E-30 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 371 382 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 SUPERFAMILY SSF142019 45 269 5.36E-84 T 29-03-2018 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 SUPERFAMILY SSF142984 270 353 1.57E-26 T 29-03-2018 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 SMART SM00928 358 403 5.0E-25 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 Pfam PF10531 SLBB domain 272 320 9.8E-13 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 SUPERFAMILY SSF140490 355 452 4.18E-38 T 29-03-2018 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 Gene3D G3DSA:3.10.560.10 264 342 1.9E-4 T 29-03-2018 CVS48_RS28680 09064689f868369d9d8ec0dc0b8b77ad 455 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 44 444 1.9E-192 T 29-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS14515 399747935ef626d7a544f2072881e905 186 Pfam PF00583 Acetyltransferase (GNAT) family 60 143 2.8E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS14515 399747935ef626d7a544f2072881e905 186 Gene3D G3DSA:3.40.630.30 23 185 2.8E-23 T 29-03-2018 CVS48_RS14515 399747935ef626d7a544f2072881e905 186 SUPERFAMILY SSF55729 24 144 1.16E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS14515 399747935ef626d7a544f2072881e905 186 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 26 181 2.1E-67 T 29-03-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 CVS48_RS23535 cefd32ed5797895740edaf1f8408149e 269 PIRSF PIRSF006157 11 269 8.2E-89 T 29-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 CVS48_RS23535 cefd32ed5797895740edaf1f8408149e 269 SUPERFAMILY SSF53213 13 268 4.45E-85 T 29-03-2018 CVS48_RS23535 cefd32ed5797895740edaf1f8408149e 269 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 16 267 1.2E-52 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CVS48_RS23535 cefd32ed5797895740edaf1f8408149e 269 Gene3D G3DSA:3.40.830.10 10 268 2.3E-82 T 29-03-2018 CVS48_RS28160 babbb9f8cabab366a2e1c7fceb9e967a 135 Pfam PF03928 Haem-degrading 7 130 3.1E-30 T 29-03-2018 IPR005624 Haem-degrading CVS48_RS28160 babbb9f8cabab366a2e1c7fceb9e967a 135 SUPERFAMILY SSF143744 2 134 1.57E-37 T 29-03-2018 CVS48_RS16725 596849e61f796d0d49c9a8a2ecea2cb1 275 Gene3D G3DSA:3.40.50.720 35 271 3.1E-18 T 29-03-2018 CVS48_RS16725 596849e61f796d0d49c9a8a2ecea2cb1 275 SUPERFAMILY SSF51735 3 270 3.07E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS16725 596849e61f796d0d49c9a8a2ecea2cb1 275 Gene3D G3DSA:3.40.50.720 1 32 7.6E-5 T 29-03-2018 CVS48_RS16725 596849e61f796d0d49c9a8a2ecea2cb1 275 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 206 1.1E-16 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS07720 0f008ecf32e53e482c5dae197e0ba0f0 290 Gene3D G3DSA:3.40.50.300 2 167 2.1E-9 T 29-03-2018 CVS48_RS07720 0f008ecf32e53e482c5dae197e0ba0f0 290 SUPERFAMILY SSF52540 3 160 2.3E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07720 0f008ecf32e53e482c5dae197e0ba0f0 290 PIRSF PIRSF005052 2 289 4.0E-109 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CVS48_RS07720 0f008ecf32e53e482c5dae197e0ba0f0 290 Pfam PF03668 P-loop ATPase protein family 3 282 6.8E-84 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CVS48_RS07720 0f008ecf32e53e482c5dae197e0ba0f0 290 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 2 286 38.456 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CVS48_RS00165 523ef4bdad03d65c93e2d347fbe9bcdf 399 Gene3D G3DSA:2.30.40.10 3 64 2.8E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS00165 523ef4bdad03d65c93e2d347fbe9bcdf 399 Gene3D G3DSA:3.20.20.140 65 352 7.4E-32 T 29-03-2018 CVS48_RS00165 523ef4bdad03d65c93e2d347fbe9bcdf 399 Pfam PF07969 Amidohydrolase family 158 390 6.7E-19 T 29-03-2018 IPR013108 Amidohydrolase 3 CVS48_RS00165 523ef4bdad03d65c93e2d347fbe9bcdf 399 SUPERFAMILY SSF51556 55 361 9.19E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS00165 523ef4bdad03d65c93e2d347fbe9bcdf 399 SUPERFAMILY SSF51338 1 55 5.47E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS00165 523ef4bdad03d65c93e2d347fbe9bcdf 399 SUPERFAMILY SSF51338 352 392 5.47E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS16575 e83289a9dcf16f164ac31f0009192b16 206 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 13 189 24.773 T 29-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 CVS48_RS16575 e83289a9dcf16f164ac31f0009192b16 206 SUPERFAMILY SSF64288 12 187 1.94E-42 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS16575 e83289a9dcf16f164ac31f0009192b16 206 Pfam PF04345 Chorismate lyase 23 189 4.9E-20 T 29-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 CVS48_RS16575 e83289a9dcf16f164ac31f0009192b16 206 Gene3D G3DSA:3.40.1410.10 9 188 4.6E-42 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CVS48_RS29025 3129ea152487d18b30c6ac0016f764b3 159 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 7 76 8.6E-25 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CVS48_RS29025 3129ea152487d18b30c6ac0016f764b3 159 Pfam PF03840 Preprotein translocase SecG subunit 7 76 1.3E-21 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CVS48_RS29025 3129ea152487d18b30c6ac0016f764b3 159 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 1.1E-29 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CVS48_RS29025 3129ea152487d18b30c6ac0016f764b3 159 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 1.1E-29 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CVS48_RS29025 3129ea152487d18b30c6ac0016f764b3 159 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 1.1E-29 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CVS48_RS29025 3129ea152487d18b30c6ac0016f764b3 159 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 1.1E-29 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CVS48_RS20655 8c96d5e2358d8a05b9b55d7e96a16f1c 515 Gene3D G3DSA:1.20.1250.20 10 209 1.2E-29 T 29-03-2018 CVS48_RS20655 8c96d5e2358d8a05b9b55d7e96a16f1c 515 Gene3D G3DSA:1.20.1250.20 264 513 7.4E-20 T 29-03-2018 CVS48_RS20655 8c96d5e2358d8a05b9b55d7e96a16f1c 515 SUPERFAMILY SSF103473 259 429 2.35E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS20655 8c96d5e2358d8a05b9b55d7e96a16f1c 515 SUPERFAMILY SSF103473 483 511 2.35E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS20655 8c96d5e2358d8a05b9b55d7e96a16f1c 515 SUPERFAMILY SSF103473 9 203 2.35E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS20655 8c96d5e2358d8a05b9b55d7e96a16f1c 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 5.0E-5 T 29-03-2018 CVS48_RS20655 8c96d5e2358d8a05b9b55d7e96a16f1c 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 410 429 5.0E-5 T 29-03-2018 CVS48_RS20655 8c96d5e2358d8a05b9b55d7e96a16f1c 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 82 104 5.0E-5 T 29-03-2018 CVS48_RS20655 8c96d5e2358d8a05b9b55d7e96a16f1c 515 Pfam PF07690 Major Facilitator Superfamily 24 419 4.6E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS13070 92aca4b6ef2b8431bd342a7232691d06 105 Pfam PF05957 Bacterial protein of unknown function (DUF883) 13 105 1.7E-30 T 29-03-2018 IPR010279 Protein of unknown function DUF883, ElaB CVS48_RS13070 92aca4b6ef2b8431bd342a7232691d06 105 Gene3D G3DSA:1.20.120.20 6 82 8.0E-4 T 29-03-2018 CVS48_RS07295 eed6612d67afc5c7aab5ba2ae520d8bd 225 SUPERFAMILY SSF55781 81 217 2.75E-6 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS07295 eed6612d67afc5c7aab5ba2ae520d8bd 225 Gene3D G3DSA:3.30.450.40 41 219 2.7E-17 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS07295 eed6612d67afc5c7aab5ba2ae520d8bd 225 Pfam PF04340 Protein of unknown function, DUF484 2 217 1.1E-30 T 29-03-2018 IPR007435 Protein of unknown function DUF484 CVS48_RS27955 e463b1012fe9e3aaa6346747df1c7ab6 172 Pfam PF06271 RDD family 13 158 2.5E-18 T 29-03-2018 IPR010432 RDD CVS48_RS16540 e38aaa9a4e46a0f980bf28559bb4a67e 559 Pfam PF02538 Hydantoinase B/oxoprolinase 3 530 5.2E-164 T 29-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 CVS48_RS02365 cf6251f3c81faff7f7a5307947b29615 328 Pfam PF03601 Conserved hypothetical protein 698 2 308 5.8E-89 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CVS48_RS02365 cf6251f3c81faff7f7a5307947b29615 328 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 3 323 9.0E-77 T 29-03-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 CVS48_RS01435 f05ddf56ba8d9e17595e60902290e6a5 321 Gene3D G3DSA:3.40.50.1100 54 108 8.0E-20 T 29-03-2018 CVS48_RS01435 f05ddf56ba8d9e17595e60902290e6a5 321 SUPERFAMILY SSF53686 7 314 1.83E-89 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS01435 f05ddf56ba8d9e17595e60902290e6a5 321 Gene3D G3DSA:3.40.50.1100 109 321 1.0E-47 T 29-03-2018 CVS48_RS01435 f05ddf56ba8d9e17595e60902290e6a5 321 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 307 2.1E-69 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 390 409 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 Pfam PF04963 Sigma-54 factor, core binding domain 137 330 2.6E-46 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 27 500 5.7E-128 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 22 66 6.8E-14 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 Gene3D G3DSA:1.10.10.10 348 440 1.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 PRINTS PR00045 Sigma-54 factor signature 402 414 2.9E-24 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 PRINTS PR00045 Sigma-54 factor signature 212 229 2.9E-24 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 PRINTS PR00045 Sigma-54 factor signature 418 429 2.9E-24 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 PRINTS PR00045 Sigma-54 factor signature 476 494 2.9E-24 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 Pfam PF04552 Sigma-54, DNA binding domain 345 501 4.0E-60 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CVS48_RS19080 375a5f825871f77af2bbe95664f5c9ba 502 PIRSF PIRSF000774 18 502 2.5E-136 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CVS48_RS05850 2d3058cbbc5bafac0950118bf39c5d18 102 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 94 1.9E-26 T 29-03-2018 CVS48_RS05850 2d3058cbbc5bafac0950118bf39c5d18 102 Gene3D G3DSA:3.10.20.30 14 91 7.1E-8 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS05850 2d3058cbbc5bafac0950118bf39c5d18 102 SUPERFAMILY SSF54292 17 94 2.1E-18 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CVS48_RS09175 5e6f2d7cf239891784277c086f5c123b 108 Pfam PF07769 psiF repeat 33 64 1.4E-16 T 29-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat CVS48_RS09175 5e6f2d7cf239891784277c086f5c123b 108 Pfam PF07769 psiF repeat 75 107 3.3E-18 T 29-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat CVS48_RS09645 2abd29d871ee83e9e07b9fe3d6e36836 357 SUPERFAMILY SSF144052 19 338 5.75E-17 T 29-03-2018 CVS48_RS25945 5c347666adaa320926924d16adf9e44f 55 SUPERFAMILY SSF57829 1 53 2.81E-19 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CVS48_RS25945 5c347666adaa320926924d16adf9e44f 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 1.7E-25 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS25945 5c347666adaa320926924d16adf9e44f 55 Pfam PF00471 Ribosomal protein L33 7 53 1.7E-17 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS25945 5c347666adaa320926924d16adf9e44f 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.773 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS24915 192d1e62fab7ad059a1c64ef23722fa2 393 Pfam PF02515 CoA-transferase family III 6 383 1.8E-125 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS24915 192d1e62fab7ad059a1c64ef23722fa2 393 SUPERFAMILY SSF89796 4 388 8.63E-130 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS24915 192d1e62fab7ad059a1c64ef23722fa2 393 Gene3D G3DSA:3.40.50.10540 2 392 3.9E-140 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS12445 f44819560da0bcb28b4e89c9f32110d1 204 Gene3D G3DSA:1.20.120.80 19 204 2.5E-51 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12445 f44819560da0bcb28b4e89c9f32110d1 204 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 25 204 1.1E-83 T 29-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 CVS48_RS12445 f44819560da0bcb28b4e89c9f32110d1 204 SUPERFAMILY SSF81452 7 202 1.07E-57 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS12445 f44819560da0bcb28b4e89c9f32110d1 204 Pfam PF00510 Cytochrome c oxidase subunit III 26 202 1.1E-14 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS07370 ef506602ce3f2828328a0ad7c8adb717 85 Gene3D G3DSA:1.10.260.40 1 84 3.2E-13 T 29-03-2018 CVS48_RS07370 ef506602ce3f2828328a0ad7c8adb717 85 Pfam PF13560 Helix-turn-helix domain 8 62 1.3E-12 T 29-03-2018 CVS48_RS07370 ef506602ce3f2828328a0ad7c8adb717 85 SUPERFAMILY SSF47413 5 71 1.6E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS07370 ef506602ce3f2828328a0ad7c8adb717 85 SMART SM00530 10 66 1.9E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS23350 b00539acd4e4b9cfdebd9b2d1a34168e 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS23350 b00539acd4e4b9cfdebd9b2d1a34168e 264 SUPERFAMILY SSF52540 2 235 6.2E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23350 b00539acd4e4b9cfdebd9b2d1a34168e 264 Pfam PF00005 ABC transporter 22 177 2.9E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS23350 b00539acd4e4b9cfdebd9b2d1a34168e 264 Gene3D G3DSA:3.40.50.300 1 239 3.4E-52 T 29-03-2018 CVS48_RS23350 b00539acd4e4b9cfdebd9b2d1a34168e 264 SMART SM00382 31 226 4.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS23275 2b34717cee7d83a188f8f089f17788df 436 Gene3D G3DSA:1.20.1600.10 44 325 2.1E-27 T 29-03-2018 CVS48_RS23275 2b34717cee7d83a188f8f089f17788df 436 SUPERFAMILY SSF111369 52 300 1.96E-79 T 29-03-2018 CVS48_RS23275 2b34717cee7d83a188f8f089f17788df 436 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 58 293 2.8E-13 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CVS48_RS23275 2b34717cee7d83a188f8f089f17788df 436 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 374 1.7E-82 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CVS48_RS08110 ae67f5b8f1d1ac8d8cc42a26572e32c4 283 Gene3D G3DSA:3.40.50.300 1 268 1.4E-37 T 29-03-2018 CVS48_RS08110 ae67f5b8f1d1ac8d8cc42a26572e32c4 283 Pfam PF13614 AAA domain 3 158 3.1E-24 T 29-03-2018 IPR025669 AAA domain CVS48_RS08110 ae67f5b8f1d1ac8d8cc42a26572e32c4 283 SUPERFAMILY SSF52540 1 263 5.32E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS14935 c7b93f803ab824697438ca4692877e36 218 SUPERFAMILY SSF46894 144 204 3.4E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS14935 c7b93f803ab824697438ca4692877e36 218 SMART SM00421 146 203 1.6E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS14935 c7b93f803ab824697438ca4692877e36 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 2.1E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS14935 c7b93f803ab824697438ca4692877e36 218 Gene3D G3DSA:1.10.10.10 109 206 3.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14935 c7b93f803ab824697438ca4692877e36 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 5.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS14935 c7b93f803ab824697438ca4692877e36 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 5.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS14935 c7b93f803ab824697438ca4692877e36 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 5.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS14935 c7b93f803ab824697438ca4692877e36 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CVS48_RS18280 7e23fa1a6e669d0a9b111403aa0e6a4f 305 Gene3D G3DSA:1.10.3720.10 3 291 3.7E-38 T 29-03-2018 CVS48_RS18280 7e23fa1a6e669d0a9b111403aa0e6a4f 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 302 5.3E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18280 7e23fa1a6e669d0a9b111403aa0e6a4f 305 SUPERFAMILY SSF161098 89 285 2.35E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS01960 b0c57d60ac4422022929b4198457ccb3 179 PIRSF PIRSF004682 1 179 8.2E-54 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 CVS48_RS01960 b0c57d60ac4422022929b4198457ccb3 179 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 3 145 1.2E-43 T 29-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CVS48_RS01960 b0c57d60ac4422022929b4198457ccb3 179 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 146 1.2E-30 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CVS48_RS01960 b0c57d60ac4422022929b4198457ccb3 179 SUPERFAMILY SSF56784 2 176 5.09E-43 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS01960 b0c57d60ac4422022929b4198457ccb3 179 Gene3D G3DSA:3.40.50.1000 1 179 8.1E-31 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS01960 b0c57d60ac4422022929b4198457ccb3 179 Pfam PF13242 HAD-hyrolase-like 99 169 2.0E-8 T 29-03-2018 CVS48_RS21690 b7fe557064f538915f16f32087be411b 176 Gene3D G3DSA:3.10.180.10 4 170 1.6E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS21690 b7fe557064f538915f16f32087be411b 176 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 132 1.1E-22 T 29-03-2018 CVS48_RS21690 b7fe557064f538915f16f32087be411b 176 SUPERFAMILY SSF54593 7 147 2.89E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS12760 41c3e2a5c18b39e09188f534f0962b7e 463 SUPERFAMILY SSF55874 321 461 3.93E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12760 41c3e2a5c18b39e09188f534f0962b7e 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 462 4.7E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12760 41c3e2a5c18b39e09188f534f0962b7e 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 5.8E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12760 41c3e2a5c18b39e09188f534f0962b7e 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 5.8E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12760 41c3e2a5c18b39e09188f534f0962b7e 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 5.8E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CVS48_RS12760 41c3e2a5c18b39e09188f534f0962b7e 463 SMART SM00387 357 463 2.5E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS12760 41c3e2a5c18b39e09188f534f0962b7e 463 Gene3D G3DSA:3.30.565.10 318 463 4.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CVS48_RS11270 b87910d49e5a0cdb96c86afad7119545 108 Gene3D G3DSA:3.10.450.50 8 107 3.6E-11 T 29-03-2018 CVS48_RS11270 b87910d49e5a0cdb96c86afad7119545 108 SUPERFAMILY SSF54427 7 99 2.14E-8 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS25065 2208ade020dda447fa3a14d79fbce581 300 Gene3D G3DSA:3.40.50.720 1 174 6.1E-36 T 29-03-2018 CVS48_RS25065 2208ade020dda447fa3a14d79fbce581 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 1.2E-39 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CVS48_RS25065 2208ade020dda447fa3a14d79fbce581 300 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CVS48_RS25065 2208ade020dda447fa3a14d79fbce581 300 Gene3D G3DSA:1.10.1040.10 175 294 2.0E-25 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS25065 2208ade020dda447fa3a14d79fbce581 300 PIRSF PIRSF000103 1 294 3.8E-68 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CVS48_RS25065 2208ade020dda447fa3a14d79fbce581 300 SUPERFAMILY SSF51735 2 163 2.87E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS25065 2208ade020dda447fa3a14d79fbce581 300 SUPERFAMILY SSF48179 165 286 8.5E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS25065 2208ade020dda447fa3a14d79fbce581 300 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 285 2.0E-33 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CVS48_RS00355 5888cd5495dab082aa2e5fb31d404e0b 141 Pfam PF08897 Domain of unknown function (DUF1841) 5 137 4.4E-57 T 29-03-2018 IPR014993 Protein of unknown function DUF1841 CVS48_RS28070 ec8ac3d9d29a126ab9bd8c2dd4a9d8e2 216 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS28070 ec8ac3d9d29a126ab9bd8c2dd4a9d8e2 216 SMART SM00882 6 206 2.8E-81 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS28070 ec8ac3d9d29a126ab9bd8c2dd4a9d8e2 216 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 212 4.2E-96 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CVS48_RS28070 ec8ac3d9d29a126ab9bd8c2dd4a9d8e2 216 Pfam PF01144 Coenzyme A transferase 7 205 2.6E-40 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS28070 ec8ac3d9d29a126ab9bd8c2dd4a9d8e2 216 Gene3D G3DSA:3.40.1080.10 3 216 5.4E-68 T 29-03-2018 CVS48_RS28070 ec8ac3d9d29a126ab9bd8c2dd4a9d8e2 216 SUPERFAMILY SSF100950 3 214 7.89E-71 T 29-03-2018 CVS48_RS03515 fa9fd995fb6eea137f26b71265566c2d 220 SUPERFAMILY SSF46689 2 60 1.05E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS03515 fa9fd995fb6eea137f26b71265566c2d 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 9.8E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS03515 fa9fd995fb6eea137f26b71265566c2d 220 Gene3D G3DSA:1.10.260.40 34 131 3.1E-9 T 29-03-2018 CVS48_RS03515 fa9fd995fb6eea137f26b71265566c2d 220 Gene3D G3DSA:1.10.10.60 2 33 1.5E-11 T 29-03-2018 CVS48_RS09210 9d5a96cfd1a8c912ac26013aba8d0997 260 SMART SM00346 14 102 6.8E-24 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS09210 9d5a96cfd1a8c912ac26013aba8d0997 260 SUPERFAMILY SSF46785 14 85 2.29E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09210 9d5a96cfd1a8c912ac26013aba8d0997 260 Gene3D G3DSA:1.10.10.10 6 80 7.0E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09210 9d5a96cfd1a8c912ac26013aba8d0997 260 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 11 257 1.6E-105 T 29-03-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 CVS48_RS09210 9d5a96cfd1a8c912ac26013aba8d0997 260 SUPERFAMILY SSF55781 78 257 4.22E-52 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09210 9d5a96cfd1a8c912ac26013aba8d0997 260 Pfam PF01614 Bacterial transcriptional regulator 129 255 1.0E-34 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CVS48_RS09210 9d5a96cfd1a8c912ac26013aba8d0997 260 Gene3D G3DSA:3.30.450.40 81 260 1.0E-56 T 29-03-2018 IPR029016 GAF domain-like CVS48_RS09210 9d5a96cfd1a8c912ac26013aba8d0997 260 Pfam PF09339 IclR helix-turn-helix domain 18 64 6.7E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CVS48_RS27440 0a0ab7305aa40657b32ba0df664877ee 304 Pfam PF00850 Histone deacetylase domain 17 301 1.1E-81 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS27440 0a0ab7305aa40657b32ba0df664877ee 304 Gene3D G3DSA:3.40.800.20 1 304 5.7E-109 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS27440 0a0ab7305aa40657b32ba0df664877ee 304 SUPERFAMILY SSF52768 2 303 1.34E-102 T 29-03-2018 CVS48_RS27440 0a0ab7305aa40657b32ba0df664877ee 304 PRINTS PR01270 Histone deacetylase superfamily signature 153 168 8.2E-18 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS27440 0a0ab7305aa40657b32ba0df664877ee 304 PRINTS PR01270 Histone deacetylase superfamily signature 231 241 8.2E-18 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS27440 0a0ab7305aa40657b32ba0df664877ee 304 PRINTS PR01270 Histone deacetylase superfamily signature 119 142 8.2E-18 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CVS48_RS03190 e179f53bbcaf8c30f8e9a76a4c42e972 144 PIRSF PIRSF001399 1 144 6.3E-57 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS03190 e179f53bbcaf8c30f8e9a76a4c42e972 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 141 2.0E-59 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS03190 e179f53bbcaf8c30f8e9a76a4c42e972 144 Pfam PF01220 Dehydroquinase class II 4 141 1.2E-58 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS03190 e179f53bbcaf8c30f8e9a76a4c42e972 144 SUPERFAMILY SSF52304 4 143 6.02E-60 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS03190 e179f53bbcaf8c30f8e9a76a4c42e972 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS03190 e179f53bbcaf8c30f8e9a76a4c42e972 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 5 143 9.1E-58 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS03190 e179f53bbcaf8c30f8e9a76a4c42e972 144 Gene3D G3DSA:3.40.50.9100 1 144 1.6E-63 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS03190 e179f53bbcaf8c30f8e9a76a4c42e972 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 70.322 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CVS48_RS17450 dacbfacbfada9c1b72903fda1ccdd6d2 321 PIRSF PIRSF018266 1 320 5.6E-66 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS17450 dacbfacbfada9c1b72903fda1ccdd6d2 321 Pfam PF16220 Domain of unknown function (DUF4880) 12 51 2.6E-13 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS17450 dacbfacbfada9c1b72903fda1ccdd6d2 321 Pfam PF04773 FecR protein 121 199 2.7E-11 T 29-03-2018 IPR006860 FecR protein CVS48_RS06510 4ed44e96e20b773545871849b27e3005 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 32.516 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06510 4ed44e96e20b773545871849b27e3005 131 Pfam PF00410 Ribosomal protein S8 5 130 3.0E-50 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06510 4ed44e96e20b773545871849b27e3005 131 Gene3D G3DSA:3.30.1370.30 2 71 1.0E-26 T 29-03-2018 CVS48_RS06510 4ed44e96e20b773545871849b27e3005 131 Gene3D G3DSA:3.30.1490.10 72 129 1.1E-21 T 29-03-2018 CVS48_RS06510 4ed44e96e20b773545871849b27e3005 131 SUPERFAMILY SSF56047 2 130 3.4E-48 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS06510 4ed44e96e20b773545871849b27e3005 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CVS48_RS03915 4019808d815706f2a9d5e348b7646fee 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 309 6.4E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS03915 4019808d815706f2a9d5e348b7646fee 328 Gene3D G3DSA:1.10.3470.10 25 313 1.1E-31 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS13190 37e3a6b0842d7e1c9fac9cd068085232 105 Gene3D G3DSA:1.10.1660.10 10 104 2.4E-6 T 29-03-2018 CVS48_RS13190 37e3a6b0842d7e1c9fac9cd068085232 105 Pfam PF13591 MerR HTH family regulatory protein 19 100 8.2E-14 T 29-03-2018 CVS48_RS27650 a862a183fc1d2e0a4033f5705fe48cf3 465 Pfam PF12801 4Fe-4S binding domain 65 101 1.7E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS27650 a862a183fc1d2e0a4033f5705fe48cf3 465 Pfam PF12801 4Fe-4S binding domain 161 184 4.6E-4 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CVS48_RS27650 a862a183fc1d2e0a4033f5705fe48cf3 465 SUPERFAMILY SSF54862 221 228 1.08E-5 T 29-03-2018 CVS48_RS27650 a862a183fc1d2e0a4033f5705fe48cf3 465 SUPERFAMILY SSF54862 160 193 1.08E-5 T 29-03-2018 CVS48_RS27650 a862a183fc1d2e0a4033f5705fe48cf3 465 SUPERFAMILY SSF54862 70 123 1.08E-5 T 29-03-2018 CVS48_RS26665 22fc7b8426d567f5efbeccff7ebf6e45 486 Gene3D G3DSA:3.30.2290.10 26 245 1.3E-53 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CVS48_RS26665 22fc7b8426d567f5efbeccff7ebf6e45 486 PIRSF PIRSF004919 23 486 3.2E-134 T 29-03-2018 IPR025502 TldD CVS48_RS26665 22fc7b8426d567f5efbeccff7ebf6e45 486 Pfam PF01523 Putative modulator of DNA gyrase 43 337 5.8E-67 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CVS48_RS26665 22fc7b8426d567f5efbeccff7ebf6e45 486 SUPERFAMILY SSF111283 28 485 1.26E-130 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CVS48_RS25940 9f66750c11028e63a9003f2895caca0e 78 Gene3D G3DSA:2.30.170.40 2 75 4.7E-33 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS25940 9f66750c11028e63a9003f2895caca0e 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 6.9E-31 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS25940 9f66750c11028e63a9003f2895caca0e 78 SUPERFAMILY SSF143800 1 77 1.24E-33 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS25940 9f66750c11028e63a9003f2895caca0e 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 23.258 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CVS48_RS25940 9f66750c11028e63a9003f2895caca0e 78 Pfam PF00830 Ribosomal L28 family 3 62 9.5E-31 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CVS48_RS28715 426218c19bf04f242bcd6139f2dd525b 205 SUPERFAMILY SSF46689 12 89 4.39E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS28715 426218c19bf04f242bcd6139f2dd525b 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 5.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS28715 426218c19bf04f242bcd6139f2dd525b 205 Gene3D G3DSA:1.10.357.10 2 205 3.7E-29 T 29-03-2018 CVS48_RS28715 426218c19bf04f242bcd6139f2dd525b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.7E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS28715 426218c19bf04f242bcd6139f2dd525b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.7E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS19280 d8f5dc7f41bc83b71b18abf1c31250f2 412 Pfam PF11862 Domain of unknown function (DUF3382) 5 98 4.7E-24 T 29-03-2018 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal CVS48_RS19280 d8f5dc7f41bc83b71b18abf1c31250f2 412 Pfam PF02653 Branched-chain amino acid transport system / permease component 108 393 9.4E-52 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS19280 d8f5dc7f41bc83b71b18abf1c31250f2 412 Gene3D G3DSA:1.10.3470.10 90 395 4.9E-44 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS22995 672fe68d57477106027211bb1dfda7dd 555 PIRSF PIRSF002741 5 549 2.9E-64 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS22995 672fe68d57477106027211bb1dfda7dd 555 Gene3D G3DSA:3.90.76.10 64 173 7.1E-24 T 29-03-2018 CVS48_RS22995 672fe68d57477106027211bb1dfda7dd 555 SUPERFAMILY SSF53850 28 548 1.6E-98 T 29-03-2018 CVS48_RS22995 672fe68d57477106027211bb1dfda7dd 555 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 444 1.0E-65 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS22995 672fe68d57477106027211bb1dfda7dd 555 Gene3D G3DSA:3.40.190.10 174 321 3.7E-28 T 29-03-2018 CVS48_RS22995 672fe68d57477106027211bb1dfda7dd 555 Gene3D G3DSA:3.10.105.10 322 527 1.5E-35 T 29-03-2018 CVS48_RS03730 32237cde9697db576a9f61dfbf574cfc 517 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 4 442 7.9E-172 T 29-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 CVS48_RS03730 32237cde9697db576a9f61dfbf574cfc 517 Gene3D G3DSA:3.30.200.20 98 243 1.3E-22 T 29-03-2018 CVS48_RS03730 32237cde9697db576a9f61dfbf574cfc 517 Pfam PF03109 ABC1 family 108 229 7.3E-33 T 29-03-2018 IPR004147 UbiB domain CVS48_RS03730 32237cde9697db576a9f61dfbf574cfc 517 SUPERFAMILY SSF56112 90 153 3.02E-42 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS03730 32237cde9697db576a9f61dfbf574cfc 517 SUPERFAMILY SSF56112 188 435 3.02E-42 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS27550 d12f5ade30bd377e7c8726d386e205fd 392 SUPERFAMILY SSF103473 4 376 6.54E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS27550 d12f5ade30bd377e7c8726d386e205fd 392 Gene3D G3DSA:1.20.1250.20 194 391 2.6E-22 T 29-03-2018 CVS48_RS27550 d12f5ade30bd377e7c8726d386e205fd 392 Gene3D G3DSA:1.20.1250.20 3 189 9.9E-24 T 29-03-2018 CVS48_RS27550 d12f5ade30bd377e7c8726d386e205fd 392 Pfam PF07690 Major Facilitator Superfamily 10 284 9.7E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS03035 9e355b829ec1652d479053e7ab11b8e9 293 Gene3D G3DSA:1.10.3470.10 1 282 1.4E-50 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS03035 9e355b829ec1652d479053e7ab11b8e9 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 277 8.7E-49 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS02635 64d76644050595589accd61dd8114b13 311 Gene3D G3DSA:3.40.190.10 178 266 1.2E-29 T 29-03-2018 CVS48_RS02635 64d76644050595589accd61dd8114b13 311 SUPERFAMILY SSF53850 89 299 9.05E-47 T 29-03-2018 CVS48_RS02635 64d76644050595589accd61dd8114b13 311 Gene3D G3DSA:3.40.190.10 92 177 3.8E-9 T 29-03-2018 CVS48_RS02635 64d76644050595589accd61dd8114b13 311 Gene3D G3DSA:1.10.10.10 1 90 8.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02635 64d76644050595589accd61dd8114b13 311 Pfam PF03466 LysR substrate binding domain 88 295 1.1E-42 T 29-03-2018 IPR005119 LysR, substrate-binding CVS48_RS02635 64d76644050595589accd61dd8114b13 311 SUPERFAMILY SSF46785 3 88 1.43E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS02635 64d76644050595589accd61dd8114b13 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CVS48_RS22730 3db7e1c88699c7d5676f8f6182c11d99 142 Gene3D G3DSA:3.30.530.20 2 141 8.5E-29 T 29-03-2018 IPR023393 START-like domain CVS48_RS22730 3db7e1c88699c7d5676f8f6182c11d99 142 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 11 138 4.5E-31 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CVS48_RS22730 3db7e1c88699c7d5676f8f6182c11d99 142 SUPERFAMILY SSF55961 2 140 2.45E-41 T 29-03-2018 CVS48_RS15510 93b39cd9b42b234c2bd3a6197bad8d5f 347 SUPERFAMILY SSF51730 37 339 3.02E-44 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CVS48_RS15510 93b39cd9b42b234c2bd3a6197bad8d5f 347 Pfam PF01619 Proline dehydrogenase 45 332 1.2E-20 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CVS48_RS15510 93b39cd9b42b234c2bd3a6197bad8d5f 347 Gene3D G3DSA:3.20.20.220 5 343 2.2E-51 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CVS48_RS10550 58a8ffc0a608620525e9400b25f3b2b0 172 Pfam PF00583 Acetyltransferase (GNAT) family 30 143 2.8E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS10550 58a8ffc0a608620525e9400b25f3b2b0 172 Gene3D G3DSA:3.40.630.30 5 172 3.3E-34 T 29-03-2018 CVS48_RS10550 58a8ffc0a608620525e9400b25f3b2b0 172 SUPERFAMILY SSF55729 6 170 4.73E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS27065 c0a612d0c7ecf1d9d1b21dba5aef2d09 560 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 13 556 4.3E-249 T 29-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative CVS48_RS27065 c0a612d0c7ecf1d9d1b21dba5aef2d09 560 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 266 4.5E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27065 c0a612d0c7ecf1d9d1b21dba5aef2d09 560 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 380 540 4.1E-7 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27065 c0a612d0c7ecf1d9d1b21dba5aef2d09 560 SUPERFAMILY SSF161098 296 536 5.98E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27065 c0a612d0c7ecf1d9d1b21dba5aef2d09 560 Gene3D G3DSA:1.10.3720.10 14 271 3.1E-38 T 29-03-2018 CVS48_RS27065 c0a612d0c7ecf1d9d1b21dba5aef2d09 560 Gene3D G3DSA:1.10.3720.10 288 553 2.6E-24 T 29-03-2018 CVS48_RS27065 c0a612d0c7ecf1d9d1b21dba5aef2d09 560 SUPERFAMILY SSF161098 16 263 5.14E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS24920 5d227bfc7d2be38b53c73df6045c800f 142 SUPERFAMILY SSF54637 14 136 1.63E-26 T 29-03-2018 IPR029069 HotDog domain CVS48_RS24920 5d227bfc7d2be38b53c73df6045c800f 142 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 31 112 8.3E-12 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CVS48_RS24920 5d227bfc7d2be38b53c73df6045c800f 142 Pfam PF03061 Thioesterase superfamily 49 116 1.2E-13 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CVS48_RS24920 5d227bfc7d2be38b53c73df6045c800f 142 Gene3D G3DSA:3.10.129.10 2 135 9.1E-26 T 29-03-2018 CVS48_RS12865 548bf323963f6ebbfbd9b110ace634c7 83 Pfam PF02597 ThiS family 9 83 7.7E-17 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CVS48_RS12865 548bf323963f6ebbfbd9b110ace634c7 83 Gene3D G3DSA:3.10.20.30 6 83 2.5E-18 T 29-03-2018 IPR012675 Beta-grasp domain CVS48_RS12865 548bf323963f6ebbfbd9b110ace634c7 83 SUPERFAMILY SSF54285 6 83 1.01E-15 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CVS48_RS11135 346dcfa470ade950aff736fff54b0a76 397 Pfam PF13458 Periplasmic binding protein 31 366 1.6E-72 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS11135 346dcfa470ade950aff736fff54b0a76 397 SUPERFAMILY SSF53822 31 380 1.26E-81 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS11135 346dcfa470ade950aff736fff54b0a76 397 Gene3D G3DSA:3.40.50.2300 18 192 1.5E-31 T 29-03-2018 CVS48_RS11135 346dcfa470ade950aff736fff54b0a76 397 Gene3D G3DSA:3.40.50.2300 194 356 2.9E-24 T 29-03-2018 CVS48_RS08260 8000b252a47eddd78710ee8414cb415b 419 Gene3D G3DSA:1.20.1600.10 39 419 9.3E-65 T 29-03-2018 CVS48_RS08260 8000b252a47eddd78710ee8414cb415b 419 Pfam PF02321 Outer membrane efflux protein 244 418 1.6E-25 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS08260 8000b252a47eddd78710ee8414cb415b 419 Pfam PF02321 Outer membrane efflux protein 45 219 3.5E-25 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS08260 8000b252a47eddd78710ee8414cb415b 419 SUPERFAMILY SSF56954 1 418 1.07E-78 T 29-03-2018 CVS48_RS14865 21e38831fb0c03d79dd7008021e819a6 152 Gene3D G3DSA:3.10.580.10 1 138 2.1E-24 T 29-03-2018 CVS48_RS14865 21e38831fb0c03d79dd7008021e819a6 152 Pfam PF00571 CBS domain 72 125 2.1E-8 T 29-03-2018 IPR000644 CBS domain CVS48_RS14865 21e38831fb0c03d79dd7008021e819a6 152 Pfam PF00571 CBS domain 16 60 9.7E-7 T 29-03-2018 IPR000644 CBS domain CVS48_RS14865 21e38831fb0c03d79dd7008021e819a6 152 SMART SM00116 78 125 0.015 T 29-03-2018 IPR000644 CBS domain CVS48_RS14865 21e38831fb0c03d79dd7008021e819a6 152 SMART SM00116 14 61 0.0071 T 29-03-2018 IPR000644 CBS domain CVS48_RS14865 21e38831fb0c03d79dd7008021e819a6 152 SUPERFAMILY SSF54631 2 126 1.64E-27 T 29-03-2018 CVS48_RS15585 9495a5f26888c2bc01ce96022dd1c593 152 SUPERFAMILY SSF46785 9 142 9.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15585 9495a5f26888c2bc01ce96022dd1c593 152 SMART SM00347 25 129 1.2E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS15585 9495a5f26888c2bc01ce96022dd1c593 152 Gene3D G3DSA:1.10.10.10 4 150 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS15585 9495a5f26888c2bc01ce96022dd1c593 152 Pfam PF12802 MarR family 34 92 6.3E-12 T 29-03-2018 CVS48_RS15585 9495a5f26888c2bc01ce96022dd1c593 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 4.0E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS15585 9495a5f26888c2bc01ce96022dd1c593 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 4.0E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS15585 9495a5f26888c2bc01ce96022dd1c593 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 4.0E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS11365 9b5543edcf352cfa37302e5cd5c59439 286 Gene3D G3DSA:3.40.50.1820 5 246 1.9E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS11365 9b5543edcf352cfa37302e5cd5c59439 286 Pfam PF07859 alpha/beta hydrolase fold 67 182 5.2E-22 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CVS48_RS11365 9b5543edcf352cfa37302e5cd5c59439 286 SUPERFAMILY SSF53474 27 264 1.37E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS08950 a4de7cfcc1466b47112f4af91ada7652 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 288 2.6E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS08950 a4de7cfcc1466b47112f4af91ada7652 304 Gene3D G3DSA:1.10.3470.10 1 291 8.6E-43 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS26145 c46a806d430b733a116379b71a99926c 241 Gene3D G3DSA:3.20.20.370 13 236 1.2E-41 T 29-03-2018 CVS48_RS26145 c46a806d430b733a116379b71a99926c 241 Pfam PF01522 Polysaccharide deacetylase 57 194 5.8E-30 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CVS48_RS26145 c46a806d430b733a116379b71a99926c 241 SUPERFAMILY SSF88713 21 215 3.95E-41 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CVS48_RS07035 8826142c75dc5a7b2967cc99330ca707 292 Pfam PF01061 ABC-2 type transporter 49 252 2.9E-13 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CVS48_RS08630 59c9b0ae7eb3f16e3e09d8c2e209c851 159 Pfam PF01575 MaoC like domain 20 137 1.4E-27 T 29-03-2018 IPR002539 MaoC-like domain CVS48_RS08630 59c9b0ae7eb3f16e3e09d8c2e209c851 159 Gene3D G3DSA:3.10.129.10 6 157 1.1E-31 T 29-03-2018 CVS48_RS08630 59c9b0ae7eb3f16e3e09d8c2e209c851 159 SUPERFAMILY SSF54637 18 158 4.87E-34 T 29-03-2018 IPR029069 HotDog domain CVS48_RS14045 1e5c2e329242b85c3665203f2679a788 189 Pfam PF04542 Sigma-70 region 2 29 97 7.9E-20 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14045 1e5c2e329242b85c3665203f2679a788 189 SUPERFAMILY SSF88946 6 109 7.46E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14045 1e5c2e329242b85c3665203f2679a788 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 188 6.8E-26 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14045 1e5c2e329242b85c3665203f2679a788 189 Pfam PF08281 Sigma-70, region 4 137 184 2.1E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14045 1e5c2e329242b85c3665203f2679a788 189 SUPERFAMILY SSF88659 132 188 4.8E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS14045 1e5c2e329242b85c3665203f2679a788 189 Gene3D G3DSA:1.10.10.10 91 189 2.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS14045 1e5c2e329242b85c3665203f2679a788 189 Gene3D G3DSA:1.10.1740.10 13 90 9.3E-23 T 29-03-2018 CVS48_RS25820 610ea537451a1bb67acc321d07b72918 170 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 8 153 2.6E-27 T 29-03-2018 IPR008136 CinA, C-terminal CVS48_RS25820 610ea537451a1bb67acc321d07b72918 170 SUPERFAMILY SSF142433 4 159 3.53E-41 T 29-03-2018 IPR008136 CinA, C-terminal CVS48_RS25820 610ea537451a1bb67acc321d07b72918 170 Pfam PF02464 Competence-damaged protein 5 157 5.3E-39 T 29-03-2018 IPR008136 CinA, C-terminal CVS48_RS25820 610ea537451a1bb67acc321d07b72918 170 Gene3D G3DSA:3.90.950.20 2 163 3.4E-43 T 29-03-2018 CVS48_RS23440 4b4622b3960e91e56b88acb30fd3791c 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CVS48_RS23440 4b4622b3960e91e56b88acb30fd3791c 385 Gene3D G3DSA:2.40.110.10 127 227 3.5E-28 T 29-03-2018 CVS48_RS23440 4b4622b3960e91e56b88acb30fd3791c 385 Gene3D G3DSA:1.10.540.10 8 125 9.0E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS23440 4b4622b3960e91e56b88acb30fd3791c 385 SUPERFAMILY SSF47203 238 381 4.57E-6 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS23440 4b4622b3960e91e56b88acb30fd3791c 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 275 382 3.6E-4 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CVS48_RS23440 4b4622b3960e91e56b88acb30fd3791c 385 SUPERFAMILY SSF56645 15 248 6.81E-60 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CVS48_RS23440 4b4622b3960e91e56b88acb30fd3791c 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 123 5.8E-20 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CVS48_RS23440 4b4622b3960e91e56b88acb30fd3791c 385 Gene3D G3DSA:1.20.140.10 228 384 1.3E-19 T 29-03-2018 CVS48_RS23440 4b4622b3960e91e56b88acb30fd3791c 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 226 2.2E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CVS48_RS14050 ca8a525561db8591fb93f83c7ca9a968 187 Pfam PF11937 Protein of unknown function (DUF3455) 46 185 1.6E-31 T 29-03-2018 IPR021851 Protein of unknown function DUF3455 CVS48_RS10200 837e4fa4a091e20d84ca240b1ba14790 237 Pfam PF12679 ABC-2 family transporter protein 55 188 1.4E-10 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CVS48_RS05795 1310fdf74c05141f253e260aee113683 203 SUPERFAMILY SSF51735 1 202 2.0E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS05795 1310fdf74c05141f253e260aee113683 203 Gene3D G3DSA:3.40.50.720 1 203 6.2E-29 T 29-03-2018 CVS48_RS05795 1310fdf74c05141f253e260aee113683 203 Pfam PF13460 NAD(P)H-binding 7 191 5.1E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS01840 27235739b7121433107d7c63bbe1a9b8 162 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 8 136 2.6E-39 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CVS48_RS01840 27235739b7121433107d7c63bbe1a9b8 162 SUPERFAMILY SSF55083 6 156 1.57E-48 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CVS48_RS01840 27235739b7121433107d7c63bbe1a9b8 162 Gene3D G3DSA:3.30.70.560 4 161 1.7E-52 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CVS48_RS01840 27235739b7121433107d7c63bbe1a9b8 162 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 91 102 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CVS48_RS01840 27235739b7121433107d7c63bbe1a9b8 162 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 9 136 4.2E-35 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CVS48_RS04275 016371754a514e5414ef1f773a612636 75 Pfam PF11142 Protein of unknown function (DUF2917) 3 61 1.2E-13 T 29-03-2018 IPR021317 Protein of unknown function DUF2917 CVS48_RS28840 96ed808ac144c274b09e01d7d594316f 289 SUPERFAMILY SSF53474 29 281 1.79E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS28840 96ed808ac144c274b09e01d7d594316f 289 Gene3D G3DSA:3.40.50.1820 20 286 4.2E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS06020 d00d74940644db2940500b0b0f5a4241 637 Pfam PF14903 WG containing repeat 281 306 9.5E-5 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS06020 d00d74940644db2940500b0b0f5a4241 637 Pfam PF14903 WG containing repeat 308 339 0.062 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS06020 d00d74940644db2940500b0b0f5a4241 637 Pfam PF14903 WG containing repeat 341 370 2.0E-5 T 29-03-2018 IPR032774 WG containing repeat CVS48_RS08970 e146d66c0ab770b3b0c98ecc746e167e 313 SUPERFAMILY SSF51569 8 300 4.58E-77 T 29-03-2018 CVS48_RS08970 e146d66c0ab770b3b0c98ecc746e167e 313 Gene3D G3DSA:3.20.20.70 6 302 4.0E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS08970 e146d66c0ab770b3b0c98ecc746e167e 313 Pfam PF00682 HMGL-like 11 282 4.0E-53 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CVS48_RS15790 1ad72fd20a272e709a6ec3d65d78bfcf 78 SMART SM00966 4 50 4.8E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CVS48_RS15790 1ad72fd20a272e709a6ec3d65d78bfcf 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 44 2.6E-13 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CVS48_RS15790 1ad72fd20a272e709a6ec3d65d78bfcf 78 Gene3D G3DSA:2.10.260.10 1 44 2.5E-14 T 29-03-2018 CVS48_RS15790 1ad72fd20a272e709a6ec3d65d78bfcf 78 SUPERFAMILY SSF89447 1 40 2.09E-12 T 29-03-2018 CVS48_RS23335 19b4f7a230142a6ca4b357450c73f28d 503 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 285 298 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CVS48_RS23335 19b4f7a230142a6ca4b357450c73f28d 503 Gene3D G3DSA:1.20.1250.20 1 199 7.8E-6 T 29-03-2018 CVS48_RS23335 19b4f7a230142a6ca4b357450c73f28d 503 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 182 481 23.497 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CVS48_RS23335 19b4f7a230142a6ca4b357450c73f28d 503 Gene3D G3DSA:3.40.50.150 262 478 2.5E-38 T 29-03-2018 CVS48_RS23335 19b4f7a230142a6ca4b357450c73f28d 503 SUPERFAMILY SSF53335 207 475 6.14E-66 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS23335 19b4f7a230142a6ca4b357450c73f28d 503 SUPERFAMILY SSF103473 2 191 4.84E-8 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS23335 19b4f7a230142a6ca4b357450c73f28d 503 Pfam PF01564 Spermine/spermidine synthase domain 264 444 1.2E-32 T 29-03-2018 CVS48_RS27270 f5d8d315f7ddbec6871a2a4bbabc56a1 439 Pfam PF14535 AMP-binding enzyme C-terminal domain 338 435 9.5E-24 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal CVS48_RS27270 f5d8d315f7ddbec6871a2a4bbabc56a1 439 PIRSF PIRSF006444 3 437 5.4E-207 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CVS48_RS27270 f5d8d315f7ddbec6871a2a4bbabc56a1 439 Gene3D G3DSA:3.30.300.30 328 438 4.4E-9 T 29-03-2018 CVS48_RS27270 f5d8d315f7ddbec6871a2a4bbabc56a1 439 SUPERFAMILY SSF56801 22 432 3.4E-63 T 29-03-2018 CVS48_RS27270 f5d8d315f7ddbec6871a2a4bbabc56a1 439 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 14 435 1.3E-217 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CVS48_RS27270 f5d8d315f7ddbec6871a2a4bbabc56a1 439 Pfam PF00501 AMP-binding enzyme 90 292 1.5E-17 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS27270 f5d8d315f7ddbec6871a2a4bbabc56a1 439 Gene3D G3DSA:3.40.50.980 87 261 2.6E-22 T 29-03-2018 CVS48_RS05965 b3ec963b7d06914e648e20875b71f7f1 98 ProSitePatterns PS00151 Acylphosphatase signature 2. 41 57 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CVS48_RS05965 b3ec963b7d06914e648e20875b71f7f1 98 SUPERFAMILY SSF54975 10 92 1.35E-25 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CVS48_RS05965 b3ec963b7d06914e648e20875b71f7f1 98 Pfam PF00708 Acylphosphatase 15 96 1.4E-24 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CVS48_RS05965 b3ec963b7d06914e648e20875b71f7f1 98 PRINTS PR00112 Acylphosphatase signature 12 27 6.5E-7 T 29-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CVS48_RS05965 b3ec963b7d06914e648e20875b71f7f1 98 PRINTS PR00112 Acylphosphatase signature 33 58 6.5E-7 T 29-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CVS48_RS05965 b3ec963b7d06914e648e20875b71f7f1 98 Gene3D G3DSA:3.30.70.100 2 97 2.5E-27 T 29-03-2018 CVS48_RS24690 e11c71d4433857db02b97d8a6df8032f 283 SUPERFAMILY SSF55486 56 223 3.09E-5 T 29-03-2018 CVS48_RS24690 e11c71d4433857db02b97d8a6df8032f 283 Pfam PF04228 Putative neutral zinc metallopeptidase 1 278 1.3E-118 T 29-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CVS48_RS18485 d6eb6c89c2605174558261ef09e59e15 479 Pfam PF02321 Outer membrane efflux protein 66 262 1.2E-17 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS18485 d6eb6c89c2605174558261ef09e59e15 479 Pfam PF02321 Outer membrane efflux protein 293 470 5.9E-22 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS18485 d6eb6c89c2605174558261ef09e59e15 479 Gene3D G3DSA:1.20.1600.10 20 478 9.5E-91 T 29-03-2018 CVS48_RS18485 d6eb6c89c2605174558261ef09e59e15 479 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 474 7.9E-94 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS18485 d6eb6c89c2605174558261ef09e59e15 479 SUPERFAMILY SSF56954 3 476 1.18E-96 T 29-03-2018 CVS48_RS22365 5a5efabff7c242a664d80cc8d13dc598 363 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 336 1.5E-53 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS22365 5a5efabff7c242a664d80cc8d13dc598 363 Gene3D G3DSA:1.10.3470.10 30 342 4.1E-49 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS16980 0fe87c6b51a34131ec903d45f130cf24 149 PIRSF PIRSF019404 1 148 8.2E-49 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CVS48_RS16980 0fe87c6b51a34131ec903d45f130cf24 149 Pfam PF02050 Flagellar FliJ protein 19 141 2.6E-33 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CVS48_RS16980 0fe87c6b51a34131ec903d45f130cf24 149 PRINTS PR01004 Flagellar FliJ protein signature 44 61 2.2E-14 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CVS48_RS16980 0fe87c6b51a34131ec903d45f130cf24 149 PRINTS PR01004 Flagellar FliJ protein signature 63 84 2.2E-14 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CVS48_RS16980 0fe87c6b51a34131ec903d45f130cf24 149 PRINTS PR01004 Flagellar FliJ protein signature 108 126 2.2E-14 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CVS48_RS16980 0fe87c6b51a34131ec903d45f130cf24 149 PRINTS PR01004 Flagellar FliJ protein signature 4 26 2.2E-14 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CVS48_RS16980 0fe87c6b51a34131ec903d45f130cf24 149 PRINTS PR01004 Flagellar FliJ protein signature 126 146 2.2E-14 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CVS48_RS16980 0fe87c6b51a34131ec903d45f130cf24 149 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 144 6.3E-31 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CVS48_RS00060 fd648247e5e6117a741139e5876a8623 257 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CVS48_RS00060 fd648247e5e6117a741139e5876a8623 257 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 26 165 3.2E-33 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CVS48_RS00060 fd648247e5e6117a741139e5876a8623 257 Pfam PF01066 CDP-alcohol phosphatidyltransferase 19 82 1.5E-13 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CVS48_RS29115 fd648247e5e6117a741139e5876a8623 257 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CVS48_RS29115 fd648247e5e6117a741139e5876a8623 257 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 26 165 3.2E-33 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CVS48_RS29115 fd648247e5e6117a741139e5876a8623 257 Pfam PF01066 CDP-alcohol phosphatidyltransferase 19 82 1.5E-13 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CVS48_RS21260 8d3d5f51fa6b75a2a7c61a1da25867b6 185 Pfam PF07209 Protein of unknown function (DUF1415) 11 180 1.0E-70 T 29-03-2018 IPR009858 Protein of unknown function DUF1415 CVS48_RS23385 373992981c36adb1d8ac321016c981fe 383 Pfam PF17408 Malonyl-CoA decarboxylase N-terminal domain 19 100 1.0E-13 T 29-03-2018 IPR035372 Malonyl-CoA decarboxylase, N-terminal KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247 CVS48_RS23385 373992981c36adb1d8ac321016c981fe 383 Pfam PF05292 Malonyl-CoA decarboxylase C-terminal domain 103 357 4.3E-100 T 29-03-2018 IPR007956 Malonyl-CoA decarboxylase, C-terminal GO:0006633|GO:0050080 KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247 CVS48_RS08725 61d929b9928c3ab00a81876daad9fddb 267 SUPERFAMILY SSF56281 29 244 2.03E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS08725 61d929b9928c3ab00a81876daad9fddb 267 Gene3D G3DSA:3.60.15.10 2 243 6.4E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS08725 61d929b9928c3ab00a81876daad9fddb 267 Pfam PF00753 Metallo-beta-lactamase superfamily 40 206 2.9E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS08725 61d929b9928c3ab00a81876daad9fddb 267 SMART SM00849 38 238 5.9E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS03700 2e5c18d86dd90ed9081d7b901615dc51 280 Gene3D G3DSA:3.40.1190.20 1 280 1.5E-64 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS03700 2e5c18d86dd90ed9081d7b901615dc51 280 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 16 276 1.6E-91 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CVS48_RS03700 2e5c18d86dd90ed9081d7b901615dc51 280 SUPERFAMILY SSF53613 13 279 3.43E-77 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS03700 2e5c18d86dd90ed9081d7b901615dc51 280 Pfam PF08543 Phosphomethylpyrimidine kinase 23 274 9.6E-89 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CVS48_RS25100 1d32bbf1d728244eebe0f25f2f8a1189 330 Gene3D G3DSA:3.40.190.10 128 239 8.8E-15 T 29-03-2018 CVS48_RS25100 1d32bbf1d728244eebe0f25f2f8a1189 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 325 5.9E-88 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25100 1d32bbf1d728244eebe0f25f2f8a1189 330 SUPERFAMILY SSF53850 117 284 2.41E-18 T 29-03-2018 CVS48_RS25100 1d32bbf1d728244eebe0f25f2f8a1189 330 PIRSF PIRSF017082 1 329 2.1E-87 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS26675 927f5a3387b4145ecc8d46dc013be1ea 215 Pfam PF13590 Domain of unknown function (DUF4136) 36 202 7.0E-25 T 29-03-2018 IPR025411 Domain of unknown function DUF4136 CVS48_RS27825 16d83601ac7ad82f5e37cb25302ef146 401 Pfam PF06181 Urate oxidase N-terminal 4 300 3.9E-131 T 29-03-2018 IPR010389 Urate oxidase N-terminal CVS48_RS27825 16d83601ac7ad82f5e37cb25302ef146 401 SUPERFAMILY SSF46626 301 398 2.83E-8 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS20325 b2f235c182236deabfbf24d7d513360f 399 PIRSF PIRSF000524 5 394 1.4E-130 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CVS48_RS20325 b2f235c182236deabfbf24d7d513360f 399 SUPERFAMILY SSF53383 10 374 7.26E-103 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS20325 b2f235c182236deabfbf24d7d513360f 399 Gene3D G3DSA:3.40.640.10 20 276 6.3E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS20325 b2f235c182236deabfbf24d7d513360f 399 Gene3D G3DSA:3.90.1150.10 277 398 5.7E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS20325 b2f235c182236deabfbf24d7d513360f 399 Pfam PF00266 Aminotransferase class-V 13 328 4.9E-37 T 29-03-2018 IPR000192 Aminotransferase class V domain CVS48_RS03705 10d720b51edbab381444ea42a1638783 226 SUPERFAMILY SSF53335 8 189 9.82E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS03705 10d720b51edbab381444ea42a1638783 226 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 17 209 1.3E-34 T 29-03-2018 CVS48_RS03705 10d720b51edbab381444ea42a1638783 226 Gene3D G3DSA:3.40.50.150 2 223 3.6E-30 T 29-03-2018 CVS48_RS07545 1f53306bcf5657a2d548aac3bc516989 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 329 3.3E-30 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS07545 1f53306bcf5657a2d548aac3bc516989 354 Gene3D G3DSA:1.10.3470.10 32 334 2.8E-29 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS27005 f0dc240dbe689890e43c192f3d36066b 307 PIRSF PIRSF009141 29 295 2.1E-101 T 29-03-2018 IPR008535 Protein of unknown function DUF817 CVS48_RS27005 f0dc240dbe689890e43c192f3d36066b 307 Pfam PF05675 Protein of unknown function (DUF817) 38 274 5.4E-106 T 29-03-2018 IPR008535 Protein of unknown function DUF817 CVS48_RS21310 e6b3dd4480669968f2c31b1dbc77696c 342 PIRSF PIRSF006470 1 339 1.1E-84 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS21310 e6b3dd4480669968f2c31b1dbc77696c 342 Gene3D G3DSA:3.40.190.10 149 331 0.0022 T 29-03-2018 CVS48_RS21310 e6b3dd4480669968f2c31b1dbc77696c 342 SUPERFAMILY SSF53850 157 211 5.97E-6 T 29-03-2018 CVS48_RS21310 e6b3dd4480669968f2c31b1dbc77696c 342 SUPERFAMILY SSF53850 77 124 5.97E-6 T 29-03-2018 CVS48_RS21310 e6b3dd4480669968f2c31b1dbc77696c 342 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 35 275 2.5E-61 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS21310 e6b3dd4480669968f2c31b1dbc77696c 342 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 323 2.8E-76 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS26615 84236da8167754b9c023fee9f77678f7 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 325 4.0E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS26615 84236da8167754b9c023fee9f77678f7 329 Gene3D G3DSA:3.40.190.10 131 326 2.0E-6 T 29-03-2018 CVS48_RS26615 84236da8167754b9c023fee9f77678f7 329 PIRSF PIRSF017082 1 328 7.4E-79 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS26615 84236da8167754b9c023fee9f77678f7 329 SUPERFAMILY SSF53850 116 286 1.09E-9 T 29-03-2018 CVS48_RS07320 e8f15727d388d3d6df6f3067d3e5ffb3 535 ProSitePatterns PS00571 Amidases signature. 159 190 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CVS48_RS07320 e8f15727d388d3d6df6f3067d3e5ffb3 535 Pfam PF01425 Amidase 31 249 1.2E-74 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS07320 e8f15727d388d3d6df6f3067d3e5ffb3 535 Pfam PF01425 Amidase 335 511 6.9E-16 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS07320 e8f15727d388d3d6df6f3067d3e5ffb3 535 SUPERFAMILY SSF75304 5 259 1.02E-111 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS07320 e8f15727d388d3d6df6f3067d3e5ffb3 535 SUPERFAMILY SSF75304 322 520 1.02E-111 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS07320 e8f15727d388d3d6df6f3067d3e5ffb3 535 Gene3D G3DSA:3.90.1300.10 5 533 1.4E-122 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS00975 340c8f6b086e023c1d3558da05716833 291 Gene3D G3DSA:3.40.50.300 1 277 1.1E-47 T 29-03-2018 CVS48_RS00975 340c8f6b086e023c1d3558da05716833 291 Pfam PF13614 AAA domain 1 168 2.4E-25 T 29-03-2018 IPR025669 AAA domain CVS48_RS00975 340c8f6b086e023c1d3558da05716833 291 SUPERFAMILY SSF52540 1 266 9.46E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21770 d4b8ce8dcb4c72a576b29773c492b25e 237 SMART SM00862 156 233 5.2E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS21770 d4b8ce8dcb4c72a576b29773c492b25e 237 SUPERFAMILY SSF52172 8 135 1.57E-39 T 29-03-2018 IPR011006 CheY-like superfamily CVS48_RS21770 d4b8ce8dcb4c72a576b29773c492b25e 237 Gene3D G3DSA:3.40.50.2300 3 130 1.0E-34 T 29-03-2018 CVS48_RS21770 d4b8ce8dcb4c72a576b29773c492b25e 237 SUPERFAMILY SSF46894 133 233 2.67E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CVS48_RS21770 d4b8ce8dcb4c72a576b29773c492b25e 237 SMART SM00448 10 120 3.5E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS21770 d4b8ce8dcb4c72a576b29773c492b25e 237 Pfam PF00072 Response regulator receiver domain 12 120 4.4E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CVS48_RS21770 d4b8ce8dcb4c72a576b29773c492b25e 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 233 1.4E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CVS48_RS21770 d4b8ce8dcb4c72a576b29773c492b25e 237 Gene3D G3DSA:1.10.10.10 131 237 3.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS18460 0dd2a734c150d17d4e6ab265c2650016 490 Pfam PF03929 PepSY-associated TM region 29 425 4.0E-65 T 29-03-2018 IPR005625 PepSY-associated TM protein CVS48_RS05340 1fd1a5daa26be8754ae18a38e51638e2 308 SUPERFAMILY SSF161098 92 291 3.53E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05340 1fd1a5daa26be8754ae18a38e51638e2 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 308 2.7E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05340 1fd1a5daa26be8754ae18a38e51638e2 308 Gene3D G3DSA:1.10.3720.10 16 297 2.4E-40 T 29-03-2018 CVS48_RS05340 1fd1a5daa26be8754ae18a38e51638e2 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 67 2.1E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS05385 a6fcdf1037d6fb839ce6b5aeb96989e1 93 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 49 3.6E-9 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CVS48_RS20320 3fd7a8ac23e1c4cf542cfca33e511863 353 SUPERFAMILY SSF56601 46 332 5.41E-57 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CVS48_RS20320 3fd7a8ac23e1c4cf542cfca33e511863 353 Gene3D G3DSA:3.40.710.10 38 350 5.6E-40 T 29-03-2018 CVS48_RS20320 3fd7a8ac23e1c4cf542cfca33e511863 353 Pfam PF00144 Beta-lactamase 53 335 4.0E-19 T 29-03-2018 IPR001466 Beta-lactamase-related CVS48_RS05075 0e48c36df099df7d4da968af970d3773 270 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05075 0e48c36df099df7d4da968af970d3773 270 SMART SM00382 44 225 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS05075 0e48c36df099df7d4da968af970d3773 270 Gene3D G3DSA:3.40.50.300 1 266 1.4E-62 T 29-03-2018 CVS48_RS05075 0e48c36df099df7d4da968af970d3773 270 SUPERFAMILY SSF52540 29 240 1.28E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05075 0e48c36df099df7d4da968af970d3773 270 Pfam PF00005 ABC transporter 35 177 9.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS28595 c710a0f8c999cdaf9705ee992483e8d6 182 SUPERFAMILY SSF52833 4 181 1.1E-43 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS28595 c710a0f8c999cdaf9705ee992483e8d6 182 PIRSF PIRSF000239 1 182 8.4E-39 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS28595 c710a0f8c999cdaf9705ee992483e8d6 182 Gene3D G3DSA:3.40.30.10 1 167 1.1E-29 T 29-03-2018 CVS48_RS28595 c710a0f8c999cdaf9705ee992483e8d6 182 Pfam PF00578 AhpC/TSA family 6 143 3.9E-24 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS20720 1f3927c15de6395dab8e692396c81ebc 571 Gene3D G3DSA:1.25.40.10 5 493 3.3E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS20720 1f3927c15de6395dab8e692396c81ebc 571 SMART SM00990 452 566 1.9E-43 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 CVS48_RS20720 1f3927c15de6395dab8e692396c81ebc 571 Pfam PF08774 VRR-NUC domain 457 566 1.9E-31 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 CVS48_RS22425 7157fe29b07d784f5e334511c12e3af1 170 Pfam PF02643 Uncharacterized ACR, COG1430 65 166 3.7E-34 T 29-03-2018 IPR003795 Protein of unknown function DUF192 CVS48_RS17290 fbb9361a5396e3c1317315a76056a403 386 Gene3D G3DSA:3.30.160.60 76 110 0.0021 T 29-03-2018 CVS48_RS17290 fbb9361a5396e3c1317315a76056a403 386 Gene3D G3DSA:3.30.160.60 304 338 6.3E-10 T 29-03-2018 CVS48_RS17290 fbb9361a5396e3c1317315a76056a403 386 Pfam PF02618 YceG-like family 45 329 1.3E-74 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CVS48_RS17290 fbb9361a5396e3c1317315a76056a403 386 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 10 336 31.058 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CVS48_RS17290 fbb9361a5396e3c1317315a76056a403 386 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 8 333 1.2E-80 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CVS48_RS26935 bad9b9d0f6be9cc1705a686303d3bcdd 188 Pfam PF09335 SNARE associated Golgi protein 25 145 3.5E-20 T 29-03-2018 IPR032816 SNARE associated Golgi protein CVS48_RS07345 b63ff37ca59065d1f5cdf29dfaee16ce 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 33 49 2.1E-8 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS07345 b63ff37ca59065d1f5cdf29dfaee16ce 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 290 303 2.1E-8 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS07345 b63ff37ca59065d1f5cdf29dfaee16ce 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 55 71 2.1E-8 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CVS48_RS07345 b63ff37ca59065d1f5cdf29dfaee16ce 396 Gene3D G3DSA:3.40.50.2300 209 376 5.1E-19 T 29-03-2018 CVS48_RS07345 b63ff37ca59065d1f5cdf29dfaee16ce 396 Pfam PF13458 Periplasmic binding protein 32 363 3.4E-58 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS07345 b63ff37ca59065d1f5cdf29dfaee16ce 396 Gene3D G3DSA:3.40.50.2300 17 208 1.3E-36 T 29-03-2018 CVS48_RS07345 b63ff37ca59065d1f5cdf29dfaee16ce 396 SUPERFAMILY SSF53822 31 373 1.65E-75 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS05605 04d10ffd745bc650a87d5d0f5636a5f4 116 Pfam PF02627 Carboxymuconolactone decarboxylase family 18 101 6.7E-20 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS05605 04d10ffd745bc650a87d5d0f5636a5f4 116 Gene3D G3DSA:1.20.1290.10 4 115 1.8E-28 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS05605 04d10ffd745bc650a87d5d0f5636a5f4 116 SUPERFAMILY SSF69118 10 105 2.22E-26 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS18880 66f068379a4821800a5b340d633bc97c 203 Gene3D G3DSA:1.10.357.10 71 199 3.0E-28 T 29-03-2018 CVS48_RS18880 66f068379a4821800a5b340d633bc97c 203 Gene3D G3DSA:1.10.10.60 5 70 2.4E-14 T 29-03-2018 CVS48_RS18880 66f068379a4821800a5b340d633bc97c 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.6E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS18880 66f068379a4821800a5b340d633bc97c 203 SUPERFAMILY SSF48498 93 197 3.81E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS18880 66f068379a4821800a5b340d633bc97c 203 SUPERFAMILY SSF46689 22 99 1.33E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS18880 66f068379a4821800a5b340d633bc97c 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS18880 66f068379a4821800a5b340d633bc97c 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS18555 465a8913c6d06266a7d93831e4f011a2 150 Gene3D G3DSA:3.40.50.620 2 150 6.5E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS18555 465a8913c6d06266a7d93831e4f011a2 150 SUPERFAMILY SSF52402 1 147 2.43E-35 T 29-03-2018 CVS48_RS18555 465a8913c6d06266a7d93831e4f011a2 150 PRINTS PR01438 Universal stress protein signature 2 20 9.4E-20 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS18555 465a8913c6d06266a7d93831e4f011a2 150 PRINTS PR01438 Universal stress protein signature 124 146 9.4E-20 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS18555 465a8913c6d06266a7d93831e4f011a2 150 PRINTS PR01438 Universal stress protein signature 106 118 9.4E-20 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS18555 465a8913c6d06266a7d93831e4f011a2 150 Pfam PF00582 Universal stress protein family 1 146 1.8E-29 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS21925 aa8087775fdf2c374dce82772d46870a 134 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 1.4E-68 T 29-03-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CVS48_RS21925 aa8087775fdf2c374dce82772d46870a 134 Pfam PF01592 NifU-like N terminal domain 3 125 1.1E-56 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CVS48_RS21925 aa8087775fdf2c374dce82772d46870a 134 SUPERFAMILY SSF82649 2 125 8.63E-48 T 29-03-2018 CVS48_RS21925 aa8087775fdf2c374dce82772d46870a 134 Gene3D G3DSA:3.90.1010.10 1 133 1.3E-51 T 29-03-2018 CVS48_RS21200 d6d4c473551ac9049e0b9b9969560602 706 SMART SM00671 496 534 7.5 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS21200 d6d4c473551ac9049e0b9b9969560602 706 SMART SM00671 620 655 17.0 T 29-03-2018 IPR006597 Sel1-like repeat CVS48_RS21200 d6d4c473551ac9049e0b9b9969560602 706 Gene3D G3DSA:1.25.40.10 13 669 0.0033 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS21200 d6d4c473551ac9049e0b9b9969560602 706 Pfam PF13226 Domain of unknown function (DUF4034) 15 289 2.7E-78 T 29-03-2018 IPR025115 Domain of unknown function DUF4034 CVS48_RS21200 d6d4c473551ac9049e0b9b9969560602 706 SUPERFAMILY SSF81901 518 657 1.44E-6 T 29-03-2018 CVS48_RS18755 01403054c89a7500897e2b68a4584e09 85 Pfam PF07369 Protein of unknown function (DUF1488) 2 68 1.8E-7 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CVS48_RS18755 01403054c89a7500897e2b68a4584e09 85 Gene3D G3DSA:3.30.160.140 1 69 2.1E-9 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CVS48_RS18755 01403054c89a7500897e2b68a4584e09 85 SUPERFAMILY SSF160272 3 67 9.02E-5 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CVS48_RS27835 bb7f6b5ffa02f4c6763bb70c31005077 314 Gene3D G3DSA:3.20.20.370 6 313 3.7E-58 T 29-03-2018 CVS48_RS27835 bb7f6b5ffa02f4c6763bb70c31005077 314 SUPERFAMILY SSF88713 10 310 5.28E-89 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CVS48_RS27835 bb7f6b5ffa02f4c6763bb70c31005077 314 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 10 310 7.7E-154 T 29-03-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 CVS48_RS27835 bb7f6b5ffa02f4c6763bb70c31005077 314 Pfam PF01522 Polysaccharide deacetylase 80 167 7.6E-12 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CVS48_RS21120 58fe55f2a807513784e041685b6c5cdd 260 SUPERFAMILY SSF56529 4 259 2.09E-75 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS21120 58fe55f2a807513784e041685b6c5cdd 260 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 256 3.6E-7 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS21120 58fe55f2a807513784e041685b6c5cdd 260 Gene3D G3DSA:3.90.850.10 1 260 3.6E-43 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS21120 58fe55f2a807513784e041685b6c5cdd 260 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 259 4.9E-115 T 29-03-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 CVS48_RS18535 71861dd6df81ddd5bab048cb5f8d11a8 287 Gene3D G3DSA:3.40.50.150 32 285 6.4E-31 T 29-03-2018 CVS48_RS18535 71861dd6df81ddd5bab048cb5f8d11a8 287 SUPERFAMILY SSF53335 39 252 1.14E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS18535 71861dd6df81ddd5bab048cb5f8d11a8 287 Pfam PF13649 Methyltransferase domain 66 158 9.8E-21 T 29-03-2018 CVS48_RS16065 e431360958f652e0ff2ec86c3c9c7679 796 Gene3D G3DSA:2.40.170.20 269 796 5.8E-85 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS16065 e431360958f652e0ff2ec86c3c9c7679 796 SMART SM00965 60 111 1.2E-9 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CVS48_RS16065 e431360958f652e0ff2ec86c3c9c7679 796 Pfam PF00593 TonB dependent receptor 329 795 4.5E-63 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CVS48_RS16065 e431360958f652e0ff2ec86c3c9c7679 796 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 154 795 3.1E-113 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CVS48_RS16065 e431360958f652e0ff2ec86c3c9c7679 796 Pfam PF07715 TonB-dependent Receptor Plug Domain 153 256 2.9E-18 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS16065 e431360958f652e0ff2ec86c3c9c7679 796 Gene3D G3DSA:2.170.130.10 110 268 7.5E-25 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CVS48_RS16065 e431360958f652e0ff2ec86c3c9c7679 796 SUPERFAMILY SSF56935 113 796 7.89E-133 T 29-03-2018 CVS48_RS26995 fe61e88e06cd5bc88b04ce3964e83a69 107 PIRSF PIRSF003135 1 97 1.5E-13 T 29-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 CVS48_RS26995 fe61e88e06cd5bc88b04ce3964e83a69 107 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 2 95 2.3E-29 T 29-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 CVS48_RS26995 fe61e88e06cd5bc88b04ce3964e83a69 107 SUPERFAMILY SSF50249 1 97 9.14E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CVS48_RS26995 fe61e88e06cd5bc88b04ce3964e83a69 107 Hamap MF_00720 Primosomal replication protein N [priB]. 1 96 22.597 T 29-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 CVS48_RS26995 fe61e88e06cd5bc88b04ce3964e83a69 107 Gene3D G3DSA:2.40.50.140 1 106 1.2E-6 T 29-03-2018 CVS48_RS14390 d275320c884a46ed1d5ea4db62c4c01e 292 SUPERFAMILY SSF103481 182 282 1.83E-16 T 29-03-2018 CVS48_RS14390 d275320c884a46ed1d5ea4db62c4c01e 292 SUPERFAMILY SSF103481 38 137 6.41E-9 T 29-03-2018 CVS48_RS14390 d275320c884a46ed1d5ea4db62c4c01e 292 Pfam PF00892 EamA-like transporter family 148 277 1.7E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS14390 d275320c884a46ed1d5ea4db62c4c01e 292 Pfam PF00892 EamA-like transporter family 7 136 4.7E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS28055 a4469d223a78565be599a5341b946e90 326 Pfam PF01112 Asparaginase 4 325 2.2E-122 T 29-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 CVS48_RS28055 a4469d223a78565be599a5341b946e90 326 Gene3D G3DSA:3.60.20.30 193 326 6.1E-48 T 29-03-2018 CVS48_RS28055 a4469d223a78565be599a5341b946e90 326 SUPERFAMILY SSF56235 3 155 1.52E-100 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS28055 a4469d223a78565be599a5341b946e90 326 SUPERFAMILY SSF56235 190 324 1.52E-100 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CVS48_RS11780 6a98519a0b4a80bdb74174328db3975a 361 Pfam PF01699 Sodium/calcium exchanger protein 41 185 9.9E-17 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CVS48_RS11780 6a98519a0b4a80bdb74174328db3975a 361 Pfam PF01699 Sodium/calcium exchanger protein 217 356 4.8E-7 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CVS48_RS19510 92029cfc1b35afa2c50431964db3903b 457 Pfam PF03972 MmgE/PrpD family 13 446 1.2E-133 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CVS48_RS19510 92029cfc1b35afa2c50431964db3903b 457 Gene3D G3DSA:1.10.4100.10 1 315 2.8E-96 T 29-03-2018 CVS48_RS19510 92029cfc1b35afa2c50431964db3903b 457 SUPERFAMILY SSF103378 8 451 7.32E-122 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CVS48_RS10575 6dc5ef3c2e284ec099d8188ba7f1e976 297 Pfam PF02535 ZIP Zinc transporter 149 292 1.8E-21 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CVS48_RS20395 a679b5bad579f1a0daa6065cd4dea4c1 168 Pfam PF04463 Protein of unknown function (DUF523) 4 150 5.3E-41 T 29-03-2018 IPR007553 Domain of unknown function DUF523 CVS48_RS03405 78e64fa4fca213f74a68868c3b551a94 141 SUPERFAMILY SSF54637 2 138 6.85E-39 T 29-03-2018 IPR029069 HotDog domain CVS48_RS03405 78e64fa4fca213f74a68868c3b551a94 141 Gene3D G3DSA:3.10.129.10 1 141 3.5E-28 T 29-03-2018 CVS48_RS03405 78e64fa4fca213f74a68868c3b551a94 141 Pfam PF13279 Thioesterase-like superfamily 11 132 2.9E-7 T 29-03-2018 CVS48_RS27770 f00d4c0e5a40866568de32d500798543 550 Gene3D G3DSA:1.10.3720.10 11 278 4.5E-35 T 29-03-2018 CVS48_RS27770 f00d4c0e5a40866568de32d500798543 550 Gene3D G3DSA:1.10.3720.10 295 546 3.6E-25 T 29-03-2018 CVS48_RS27770 f00d4c0e5a40866568de32d500798543 550 SUPERFAMILY SSF161098 296 544 9.94E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27770 f00d4c0e5a40866568de32d500798543 550 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 274 1.6E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27770 f00d4c0e5a40866568de32d500798543 550 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 376 543 5.4E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS27770 f00d4c0e5a40866568de32d500798543 550 SUPERFAMILY SSF161098 11 276 1.44E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS08365 f0cfc11bbde0aebf64234c65df072eeb 134 Pfam PF08805 PilS N terminal 23 119 4.8E-17 T 29-03-2018 IPR014911 Type 4 secretion system, PilS, N-terminal CVS48_RS08365 f0cfc11bbde0aebf64234c65df072eeb 134 Gene3D G3DSA:3.30.1690.10 25 133 6.4E-17 T 29-03-2018 CVS48_RS08365 f0cfc11bbde0aebf64234c65df072eeb 134 SUPERFAMILY SSF54523 21 123 1.33E-15 T 29-03-2018 CVS48_RS19920 de6e5a8a4b12fab470d7b24b86f0d4a4 543 Pfam PF00361 Proton-conducting membrane transporter 137 438 5.0E-35 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS03480 4804427cb35295a1c43a15297637fcd5 387 Gene3D G3DSA:3.40.50.2300 19 186 1.3E-24 T 29-03-2018 CVS48_RS03480 4804427cb35295a1c43a15297637fcd5 387 SUPERFAMILY SSF53822 23 386 7.33E-82 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS03480 4804427cb35295a1c43a15297637fcd5 387 Gene3D G3DSA:3.40.50.2300 187 349 5.2E-22 T 29-03-2018 CVS48_RS03480 4804427cb35295a1c43a15297637fcd5 387 Pfam PF13458 Periplasmic binding protein 23 361 4.7E-67 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS01480 06f06cb8a51d2c1974177e9220cf34b0 297 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 7 296 26.346 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CVS48_RS01480 06f06cb8a51d2c1974177e9220cf34b0 297 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 8 95 1.2E-16 T 29-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 CVS48_RS01480 06f06cb8a51d2c1974177e9220cf34b0 297 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 8 295 7.4E-56 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CVS48_RS01480 06f06cb8a51d2c1974177e9220cf34b0 297 Gene3D G3DSA:2.160.20.70 171 297 2.2E-34 T 29-03-2018 CVS48_RS01480 06f06cb8a51d2c1974177e9220cf34b0 297 SUPERFAMILY SSF63848 190 295 4.32E-30 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CVS48_RS01480 06f06cb8a51d2c1974177e9220cf34b0 297 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 191 293 4.5E-31 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CVS48_RS03885 db4670703c3e41e145b78ae815bc00f7 330 PIRSF PIRSF017082 2 330 2.2E-65 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS03885 db4670703c3e41e145b78ae815bc00f7 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 326 9.5E-62 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS03885 db4670703c3e41e145b78ae815bc00f7 330 SUPERFAMILY SSF53850 98 289 2.79E-7 T 29-03-2018 CVS48_RS03885 db4670703c3e41e145b78ae815bc00f7 330 Gene3D G3DSA:3.40.190.10 136 302 4.2E-9 T 29-03-2018 CVS48_RS25230 264d571d07e7c81e55827639005542f9 244 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 225 1.1E-51 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS25230 264d571d07e7c81e55827639005542f9 244 SUPERFAMILY SSF52096 6 235 6.97E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS25230 264d571d07e7c81e55827639005542f9 244 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CVS48_RS25230 264d571d07e7c81e55827639005542f9 244 Gene3D G3DSA:3.90.226.10 2 243 2.6E-64 T 29-03-2018 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PIRSF PIRSF019574 3 367 2.3E-140 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 Gene3D G3DSA:3.40.190.10 20 205 8.3E-34 T 29-03-2018 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 Gene3D G3DSA:3.40.190.10 206 343 1.9E-15 T 29-03-2018 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 SUPERFAMILY SSF53850 27 366 4.94E-98 T 29-03-2018 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 266 285 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 216 235 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 49 70 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 105 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 76 90 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 179 198 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 125 141 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 311 337 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 33 49 2.6E-64 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CVS48_RS26255 84e496a0a8aa2bac1591de8989114857 367 Pfam PF13416 Bacterial extracellular solute-binding protein 47 332 3.4E-35 T 29-03-2018 CVS48_RS03725 16f880a7907982918ef2d0fd6894b2a1 292 Gene3D G3DSA:1.10.620.20 3 203 5.1E-26 T 29-03-2018 CVS48_RS03725 16f880a7907982918ef2d0fd6894b2a1 292 SUPERFAMILY SSF47240 12 277 2.86E-43 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS04740 34744ea5c96e2feeaa6114a6f975fa67 195 Gene3D G3DSA:1.10.10.60 6 53 4.9E-12 T 29-03-2018 CVS48_RS04740 34744ea5c96e2feeaa6114a6f975fa67 195 Gene3D G3DSA:1.10.357.10 54 192 1.3E-24 T 29-03-2018 CVS48_RS04740 34744ea5c96e2feeaa6114a6f975fa67 195 SUPERFAMILY SSF48498 78 191 7.5E-29 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CVS48_RS04740 34744ea5c96e2feeaa6114a6f975fa67 195 SUPERFAMILY SSF46689 11 84 8.72E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS04740 34744ea5c96e2feeaa6114a6f975fa67 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 3.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CVS48_RS08815 fcf5a83f369de51f3042b30cb3164db2 417 SUPERFAMILY SSF142764 5 416 6.93E-129 T 29-03-2018 CVS48_RS08815 fcf5a83f369de51f3042b30cb3164db2 417 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 252 412 1.5E-43 T 29-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain CVS48_RS08815 fcf5a83f369de51f3042b30cb3164db2 417 Gene3D G3DSA:3.40.50.10840 4 238 1.6E-76 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CVS48_RS08815 fcf5a83f369de51f3042b30cb3164db2 417 Pfam PF07005 Putative sugar-binding N-terminal domain 5 227 3.2E-71 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CVS48_RS19715 3fbc51793ec7b267b42d01614a59269d 225 Pfam PF00005 ABC transporter 26 171 6.0E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19715 3fbc51793ec7b267b42d01614a59269d 225 SMART SM00382 35 220 6.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19715 3fbc51793ec7b267b42d01614a59269d 225 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS19715 3fbc51793ec7b267b42d01614a59269d 225 Gene3D G3DSA:3.40.50.300 2 225 5.4E-61 T 29-03-2018 CVS48_RS19715 3fbc51793ec7b267b42d01614a59269d 225 SUPERFAMILY SSF52540 7 223 1.21E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18820 c8f148950ab059c6085a2f6f3d378372 296 SUPERFAMILY SSF53335 71 200 2.2E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS18820 c8f148950ab059c6085a2f6f3d378372 296 Pfam PF13847 Methyltransferase domain 95 218 3.3E-10 T 29-03-2018 IPR025714 Methyltransferase domain CVS48_RS18820 c8f148950ab059c6085a2f6f3d378372 296 Gene3D G3DSA:3.40.50.150 24 240 3.0E-19 T 29-03-2018 CVS48_RS04360 998bb1a50b8c69581bbdaa438272b03e 290 Pfam PF11453 Protein of unknown function (DUF2950) 34 276 6.4E-63 T 29-03-2018 IPR021556 Protein of unknown function DUF2950 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 Gene3D G3DSA:2.40.160.10 8 382 8.2E-72 T 29-03-2018 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 SUPERFAMILY SSF56935 17 382 1.75E-72 T 29-03-2018 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 PRINTS PR00184 Neisseria sp. porin signature 336 360 5.9E-10 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 PRINTS PR00184 Neisseria sp. porin signature 59 84 5.9E-10 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 PRINTS PR00184 Neisseria sp. porin signature 159 176 5.9E-10 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 Pfam PF13609 Gram-negative porin 7 362 1.6E-57 T 29-03-2018 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 57 68 7.8E-5 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 160 171 7.8E-5 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 101 111 7.8E-5 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS28710 ae8d50548f7e2e96a4aeab78a82cb4e0 382 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 339 356 7.8E-5 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CVS48_RS11650 52b4f895db4ba83e2c42c5f9eb8b2883 462 Gene3D G3DSA:1.10.4100.10 2 310 9.2E-66 T 29-03-2018 CVS48_RS11650 52b4f895db4ba83e2c42c5f9eb8b2883 462 SUPERFAMILY SSF103378 10 440 4.97E-82 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CVS48_RS11650 52b4f895db4ba83e2c42c5f9eb8b2883 462 Pfam PF03972 MmgE/PrpD family 9 430 1.7E-87 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CVS48_RS15775 22e011fa298a023ffbb9c0b8279cc8c0 284 Pfam PF05853 beta-keto acid cleavage enzyme 15 281 6.9E-70 T 29-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CVS48_RS15775 22e011fa298a023ffbb9c0b8279cc8c0 284 Gene3D G3DSA:3.20.20.70 13 283 8.4E-77 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS11195 0980d68d21f0732dbd5935fd3be206f9 165 SUPERFAMILY SSF54637 15 159 6.68E-39 T 29-03-2018 IPR029069 HotDog domain CVS48_RS11195 0980d68d21f0732dbd5935fd3be206f9 165 Pfam PF01575 MaoC like domain 28 127 5.5E-26 T 29-03-2018 IPR002539 MaoC-like domain CVS48_RS11195 0980d68d21f0732dbd5935fd3be206f9 165 Gene3D G3DSA:3.10.129.10 12 161 7.2E-37 T 29-03-2018 CVS48_RS19330 a85785323d11bb00556723de48661def 198 SUPERFAMILY SSF53474 6 171 4.74E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS19330 a85785323d11bb00556723de48661def 198 Gene3D G3DSA:3.40.50.1820 6 178 2.1E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS19330 a85785323d11bb00556723de48661def 198 Pfam PF06821 Serine hydrolase 6 172 3.7E-64 T 29-03-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 CVS48_RS01730 0cfadb6420cee5f74c5a463bd6e60290 174 Pfam PF01613 Flavin reductase like domain 18 160 2.0E-34 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS01730 0cfadb6420cee5f74c5a463bd6e60290 174 SUPERFAMILY SSF50475 9 160 2.21E-46 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS01730 0cfadb6420cee5f74c5a463bd6e60290 174 SMART SM00903 17 162 1.3E-58 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CVS48_RS01730 0cfadb6420cee5f74c5a463bd6e60290 174 Gene3D G3DSA:2.30.110.10 5 172 6.8E-39 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CVS48_RS11450 b1a45bf57ee38ea076a1e3277e57e6bb 88 Pfam PF01402 Ribbon-helix-helix protein, copG family 8 45 1.5E-10 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CVS48_RS11450 b1a45bf57ee38ea076a1e3277e57e6bb 88 Gene3D G3DSA:1.10.1220.10 3 51 7.4E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CVS48_RS11450 b1a45bf57ee38ea076a1e3277e57e6bb 88 SUPERFAMILY SSF47598 5 47 3.78E-9 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CVS48_RS17740 9ecb1cc9b4d6bd6f5a8bf150cf718fbf 335 Pfam PF03741 Integral membrane protein TerC family 83 285 4.5E-54 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CVS48_RS17740 9ecb1cc9b4d6bd6f5a8bf150cf718fbf 335 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 10 316 8.9E-117 T 29-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CVS48_RS25740 f866b6bfeb0337b25ffcbecc22efd8a5 286 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 22 277 31.512 T 29-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CVS48_RS25740 f866b6bfeb0337b25ffcbecc22efd8a5 286 Gene3D G3DSA:3.40.50.620 11 281 7.6E-61 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS25740 f866b6bfeb0337b25ffcbecc22efd8a5 286 TIGRFAM TIGR00552 nadE: NAD+ synthetase 35 275 4.1E-63 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CVS48_RS25740 f866b6bfeb0337b25ffcbecc22efd8a5 286 SUPERFAMILY SSF52402 14 276 2.2E-73 T 29-03-2018 CVS48_RS25740 f866b6bfeb0337b25ffcbecc22efd8a5 286 Pfam PF02540 NAD synthase 30 274 8.8E-64 T 29-03-2018 IPR022310 NAD/GMP synthase CVS48_RS28915 6465a4aab6fe3ce3817acfc6fa495fdc 339 PIRSF PIRSF017082 6 339 1.7E-60 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS28915 6465a4aab6fe3ce3817acfc6fa495fdc 339 SUPERFAMILY SSF53850 136 297 3.04E-6 T 29-03-2018 CVS48_RS28915 6465a4aab6fe3ce3817acfc6fa495fdc 339 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 335 6.2E-56 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS28915 6465a4aab6fe3ce3817acfc6fa495fdc 339 Gene3D G3DSA:3.40.190.10 137 246 1.1E-12 T 29-03-2018 CVS48_RS00965 c759f5e68ad87717b1c4f84b47b172b6 559 Gene3D G3DSA:3.90.1530.10 31 144 1.7E-13 T 29-03-2018 CVS48_RS00965 c759f5e68ad87717b1c4f84b47b172b6 559 TIGRFAM TIGR03764 ICE_PFGI_1_parB: integrating conjugative element, PFGI_1 class, ParB family protein 28 290 1.7E-119 T 29-03-2018 IPR022304 Integrating conjugative element, PFGI-1, ParB CVS48_RS00965 c759f5e68ad87717b1c4f84b47b172b6 559 SUPERFAMILY SSF110849 37 140 8.89E-10 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CVS48_RS19310 f86d508db78bb536716538b0c46954b5 293 SUPERFAMILY SSF161098 55 281 6.54E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19310 f86d508db78bb536716538b0c46954b5 293 Gene3D G3DSA:1.10.3720.10 12 293 6.4E-43 T 29-03-2018 CVS48_RS19310 f86d508db78bb536716538b0c46954b5 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 292 1.2E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS16305 ed35f96a5d4db0ded0c3af16628b2b6a 208 Pfam PF12261 Thermostable hemolysin 32 198 2.7E-50 T 29-03-2018 IPR022050 Thermostable hemolysin CVS48_RS21320 91c42c442f081449eb5f798682e15209 281 Gene3D G3DSA:3.20.20.140 5 269 9.6E-42 T 29-03-2018 CVS48_RS21320 91c42c442f081449eb5f798682e15209 281 SUPERFAMILY SSF89550 6 86 6.47E-49 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CVS48_RS21320 91c42c442f081449eb5f798682e15209 281 SUPERFAMILY SSF89550 169 280 6.47E-49 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CVS48_RS21320 91c42c442f081449eb5f798682e15209 281 Pfam PF02811 PHP domain 9 104 3.4E-9 T 29-03-2018 IPR004013 PHP domain GO:0003824 CVS48_RS21320 91c42c442f081449eb5f798682e15209 281 SMART SM00481 8 73 1.1E-15 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CVS48_RS21070 1d893430f84977fdce38779247285564 351 Pfam PF14491 Protein of unknown function (DUF4435) 67 203 7.5E-9 T 29-03-2018 IPR029492 Domain of unknown function DUF4435 CVS48_RS14005 1475b37b3e3a990353da0f31b25d1baf 200 Pfam PF01810 LysE type translocator 13 200 4.5E-37 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS17735 895a453265d2388c51f5470ce05b5ad7 139 SUPERFAMILY SSF52402 1 139 1.0E-27 T 29-03-2018 CVS48_RS17735 895a453265d2388c51f5470ce05b5ad7 139 Gene3D G3DSA:3.40.50.620 1 139 1.7E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS17735 895a453265d2388c51f5470ce05b5ad7 139 Pfam PF00582 Universal stress protein family 2 139 1.5E-23 T 29-03-2018 IPR006016 UspA GO:0006950 CVS48_RS17735 895a453265d2388c51f5470ce05b5ad7 139 PRINTS PR01438 Universal stress protein signature 1 18 2.1E-15 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS17735 895a453265d2388c51f5470ce05b5ad7 139 PRINTS PR01438 Universal stress protein signature 100 112 2.1E-15 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS17735 895a453265d2388c51f5470ce05b5ad7 139 PRINTS PR01438 Universal stress protein signature 118 139 2.1E-15 T 29-03-2018 IPR006015 Universal stress protein A CVS48_RS13930 989a049556d0b4cde26c97e9a771da5e 368 SUPERFAMILY SSF51604 112 364 5.5E-59 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS13930 989a049556d0b4cde26c97e9a771da5e 368 Gene3D G3DSA:3.20.20.120 116 356 1.9E-48 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS13930 989a049556d0b4cde26c97e9a771da5e 368 SMART SM00922 142 238 8.5E-16 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CVS48_RS13930 989a049556d0b4cde26c97e9a771da5e 368 Pfam PF13378 Enolase C-terminal domain-like 145 356 2.9E-49 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CVS48_RS13930 989a049556d0b4cde26c97e9a771da5e 368 SUPERFAMILY SSF54826 1 126 4.27E-22 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS13930 989a049556d0b4cde26c97e9a771da5e 368 Gene3D G3DSA:3.30.390.10 1 115 3.5E-25 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CVS48_RS13930 989a049556d0b4cde26c97e9a771da5e 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 30 124 2.1E-13 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CVS48_RS21040 53c3f396236535607073e1bd6b99ea51 450 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 15 138 6.9E-30 T 29-03-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase CVS48_RS21040 53c3f396236535607073e1bd6b99ea51 450 SUPERFAMILY SSF53474 62 258 8.47E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21040 53c3f396236535607073e1bd6b99ea51 450 SUPERFAMILY SSF53474 417 430 8.47E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21040 53c3f396236535607073e1bd6b99ea51 450 SUPERFAMILY SSF53474 291 388 8.47E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21040 53c3f396236535607073e1bd6b99ea51 450 PIRSF PIRSF016521 1 439 2.8E-102 T 29-03-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 CVS48_RS21040 53c3f396236535607073e1bd6b99ea51 450 Gene3D G3DSA:3.40.50.1820 128 431 1.4E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21040 53c3f396236535607073e1bd6b99ea51 450 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 203 431 2.8E-56 T 29-03-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal CVS48_RS17280 73f97430fcf95a17a4f034a0c758f261 229 Pfam PF01988 VIT family 15 222 2.6E-53 T 29-03-2018 IPR008217 Ccc1 family CVS48_RS24370 b20fc787cc9042a4721949bd69f38bd9 998 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 746 820 2.4E-23 T 29-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal CVS48_RS24370 b20fc787cc9042a4721949bd69f38bd9 998 TIGRFAM TIGR01541 tape_meas_lam_C: phage tail tape measure protein, lambda family 592 933 8.1E-48 T 29-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal CVS48_RS24370 b20fc787cc9042a4721949bd69f38bd9 998 Pfam PF06791 Prophage tail length tape measure protein 130 333 1.2E-64 T 29-03-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal CVS48_RS13695 0517348fe775a41e20a48c9d54c82063 558 Pfam PF00474 Sodium:solute symporter family 62 477 2.5E-108 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS13695 0517348fe775a41e20a48c9d54c82063 558 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 177 202 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CVS48_RS13695 0517348fe775a41e20a48c9d54c82063 558 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 62 476 1.9E-57 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS15305 c789f9c9b266d3510e8ab5a6c6f113c1 292 Pfam PF05013 N-formylglutamate amidohydrolase 20 252 1.5E-65 T 29-03-2018 IPR007709 N-formylglutamate amidohydrolase CVS48_RS15305 c789f9c9b266d3510e8ab5a6c6f113c1 292 Gene3D G3DSA:3.40.630.40 2 285 3.4E-83 T 29-03-2018 CVS48_RS15305 c789f9c9b266d3510e8ab5a6c6f113c1 292 SUPERFAMILY SSF53187 9 281 3.45E-86 T 29-03-2018 CVS48_RS19915 636329f724767bef3e9b2c35feec9088 160 PIRSF PIRSF019239 2 160 3.4E-37 T 29-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CVS48_RS19915 636329f724767bef3e9b2c35feec9088 160 Pfam PF01899 Na+/H+ ion antiporter subunit 11 158 4.7E-40 T 29-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CVS48_RS08200 e1cd11a374ac9f0fc53172aa0345a701 219 SUPERFAMILY SSF52833 46 210 2.34E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS08200 e1cd11a374ac9f0fc53172aa0345a701 219 Gene3D G3DSA:3.40.30.10 43 219 3.4E-40 T 29-03-2018 CVS48_RS08200 e1cd11a374ac9f0fc53172aa0345a701 219 Pfam PF13462 Thioredoxin 53 211 7.8E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS00775 cf257467eaf93d80cc4b0d39b8b99c5b 199 TIGRFAM TIGR03748 conj_PilL: integrating conjugative element protein PilL, PFGI-1 class 61 164 1.0E-41 T 29-03-2018 IPR022260 Integrating conjugative element protein PilL, PFGI-1 CVS48_RS16450 d045cbf74364ef10f5e4a90a2f5cb06c 345 PIRSF PIRSF003109 2 345 7.5E-86 T 29-03-2018 IPR014407 5-methylcytosine restriction system component, bacterial GO:0009307 CVS48_RS16450 d045cbf74364ef10f5e4a90a2f5cb06c 345 Pfam PF10117 McrBC 5-methylcytosine restriction system component 14 305 4.6E-32 T 29-03-2018 IPR019292 5-methylcytosine restriction system component CVS48_RS00960 a12e0943b8d5b0c3648dc52c6a6dd446 186 Pfam PF11198 Protein of unknown function (DUF2857) 8 182 4.6E-63 T 29-03-2018 IPR021364 Protein of unknown function DUF2857 CVS48_RS25150 254de615ae9d9397ad9a6b56d7a90fae 335 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 313 5.3E-90 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS25150 254de615ae9d9397ad9a6b56d7a90fae 335 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 33 288 2.9E-80 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS25150 254de615ae9d9397ad9a6b56d7a90fae 335 PIRSF PIRSF006470 1 331 1.3E-110 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS27500 0bca6e22cc18970630847d36f021f777 231 Pfam PF02224 Cytidylate kinase 14 221 1.6E-70 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CVS48_RS27500 0bca6e22cc18970630847d36f021f777 231 Gene3D G3DSA:3.40.50.300 11 226 4.1E-48 T 29-03-2018 CVS48_RS27500 0bca6e22cc18970630847d36f021f777 231 Hamap MF_00238 Cytidylate kinase [cmk]. 12 226 32.482 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CVS48_RS27500 0bca6e22cc18970630847d36f021f777 231 SUPERFAMILY SSF52540 13 224 2.2E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS27500 0bca6e22cc18970630847d36f021f777 231 TIGRFAM TIGR00017 cmk: cytidylate kinase 12 220 7.8E-70 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CVS48_RS25360 b94f937abda76fedcbe3acba35768c0a 484 SUPERFAMILY SSF51556 67 384 2.36E-66 T 29-03-2018 IPR032466 Metal-dependent hydrolase CVS48_RS25360 b94f937abda76fedcbe3acba35768c0a 484 Gene3D G3DSA:2.30.40.10 10 81 1.4E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25360 b94f937abda76fedcbe3acba35768c0a 484 SUPERFAMILY SSF51338 29 67 2.33E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25360 b94f937abda76fedcbe3acba35768c0a 484 SUPERFAMILY SSF51338 384 455 2.33E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CVS48_RS25360 b94f937abda76fedcbe3acba35768c0a 484 Pfam PF01979 Amidohydrolase family 64 433 8.3E-42 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CVS48_RS25360 b94f937abda76fedcbe3acba35768c0a 484 Gene3D G3DSA:3.20.20.140 82 400 3.2E-48 T 29-03-2018 CVS48_RS14170 404371f80927e28f09894d79e40a57e4 285 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 20 264 5.4E-43 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CVS48_RS14170 404371f80927e28f09894d79e40a57e4 285 Gene3D G3DSA:3.40.50.970 4 277 1.7E-68 T 29-03-2018 CVS48_RS14170 404371f80927e28f09894d79e40a57e4 285 SUPERFAMILY SSF52518 4 274 4.29E-76 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CVS48_RS09750 4506de7c1123b164b5ebc760c3b3567d 418 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 16 101 5.2E-16 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CVS48_RS09750 4506de7c1123b164b5ebc760c3b3567d 418 Pfam PF13657 HipA N-terminal domain 10 96 2.4E-14 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CVS48_RS09750 4506de7c1123b164b5ebc760c3b3567d 418 Pfam PF07804 HipA-like C-terminal domain 143 360 6.1E-43 T 29-03-2018 IPR012893 HipA-like, C-terminal CVS48_RS04005 512ee997cafbefb9f6bded23be7f2685 323 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 41 193 7.3E-13 T 29-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CVS48_RS04005 512ee997cafbefb9f6bded23be7f2685 323 SUPERFAMILY SSF53187 16 320 9.24E-52 T 29-03-2018 CVS48_RS04005 512ee997cafbefb9f6bded23be7f2685 323 Gene3D G3DSA:3.40.630.10 36 262 1.3E-13 T 29-03-2018 CVS48_RS16940 efca01d287b73aceeac5346df0e43597 262 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 15 255 4.6E-73 T 29-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 CVS48_RS16940 efca01d287b73aceeac5346df0e43597 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 1.7E-29 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CVS48_RS16940 efca01d287b73aceeac5346df0e43597 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 1.7E-29 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CVS48_RS16940 efca01d287b73aceeac5346df0e43597 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 1.7E-29 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CVS48_RS16940 efca01d287b73aceeac5346df0e43597 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.7E-29 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CVS48_RS16940 efca01d287b73aceeac5346df0e43597 262 Pfam PF01311 Bacterial export proteins, family 1 15 246 1.1E-72 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CVS48_RS10025 e0cf9d8d9523a8366871e4410c784ad9 341 Gene3D G3DSA:3.40.190.10 20 139 5.0E-4 T 29-03-2018 CVS48_RS10025 e0cf9d8d9523a8366871e4410c784ad9 341 SUPERFAMILY SSF53850 24 337 1.28E-61 T 29-03-2018 CVS48_RS10025 e0cf9d8d9523a8366871e4410c784ad9 341 Gene3D G3DSA:3.40.190.10 140 293 9.8E-33 T 29-03-2018 CVS48_RS10025 e0cf9d8d9523a8366871e4410c784ad9 341 Pfam PF13343 Bacterial extracellular solute-binding protein 89 297 1.9E-27 T 29-03-2018 CVS48_RS20970 591c2ae751b13f73632af5be2d81ab45 133 Pfam PF14430 Immunity protein Imm1 52 131 2.5E-5 T 29-03-2018 IPR025680 Immunity protein Imm1 CVS48_RS01120 b67277c37b28c8a0bc1be48c0c9f0797 414 Gene3D G3DSA:3.50.50.60 30 414 1.2E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01120 b67277c37b28c8a0bc1be48c0c9f0797 414 Pfam PF01266 FAD dependent oxidoreductase 34 379 1.1E-61 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS01120 b67277c37b28c8a0bc1be48c0c9f0797 414 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 3 406 2.8E-216 T 29-03-2018 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CVS48_RS01120 b67277c37b28c8a0bc1be48c0c9f0797 414 SUPERFAMILY SSF51905 342 403 6.07E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS01120 b67277c37b28c8a0bc1be48c0c9f0797 414 SUPERFAMILY SSF51905 33 252 6.07E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS00265 d1a7890f6207ae5920905af81be10ba6 222 SMART SM00463 131 215 3.2E-16 T 29-03-2018 IPR002625 Smr domain CVS48_RS00265 d1a7890f6207ae5920905af81be10ba6 222 SUPERFAMILY SSF160443 132 215 1.57E-17 T 29-03-2018 IPR002625 Smr domain CVS48_RS00265 d1a7890f6207ae5920905af81be10ba6 222 Pfam PF01713 Smr domain 134 215 5.2E-25 T 29-03-2018 IPR002625 Smr domain CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 Gene3D G3DSA:3.40.50.720 1 45 4.8E-9 T 29-03-2018 CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 Gene3D G3DSA:3.40.50.720 46 252 2.3E-44 T 29-03-2018 CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.5E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.5E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.5E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.3E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.3E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.3E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 Pfam PF00106 short chain dehydrogenase 6 195 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 SUPERFAMILY SSF51735 3 247 1.83E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS22485 c755882e5985d9cae473e867910f709c 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 189 0.0062 T 29-03-2018 CVS48_RS26715 0b1b725832ebc85302e7fa8f8d898c4e 154 SUPERFAMILY SSF52833 4 153 3.71E-48 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS26715 0b1b725832ebc85302e7fa8f8d898c4e 154 Gene3D G3DSA:3.40.30.10 1 153 1.8E-34 T 29-03-2018 CVS48_RS26715 0b1b725832ebc85302e7fa8f8d898c4e 154 PIRSF PIRSF000239 1 153 3.4E-29 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS26715 0b1b725832ebc85302e7fa8f8d898c4e 154 Pfam PF00578 AhpC/TSA family 5 131 2.3E-33 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CVS48_RS19235 39a846c60622a2c1605880da1b4b75dd 212 SUPERFAMILY SSF52833 3 86 2.88E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS19235 39a846c60622a2c1605880da1b4b75dd 212 Gene3D G3DSA:3.40.30.10 1 100 8.3E-15 T 29-03-2018 CVS48_RS19235 39a846c60622a2c1605880da1b4b75dd 212 Gene3D G3DSA:1.20.1050.10 101 204 2.4E-5 T 29-03-2018 CVS48_RS19235 39a846c60622a2c1605880da1b4b75dd 212 Pfam PF13409 Glutathione S-transferase, N-terminal domain 17 77 2.2E-8 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS19235 39a846c60622a2c1605880da1b4b75dd 212 SUPERFAMILY SSF47616 83 204 3.41E-10 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CVS48_RS08020 39facd872cb22e51d91e822b701c4f97 532 Gene3D G3DSA:1.20.120.330 17 222 1.7E-4 T 29-03-2018 CVS48_RS08020 39facd872cb22e51d91e822b701c4f97 532 SUPERFAMILY SSF51261 397 530 9.42E-42 T 29-03-2018 IPR011055 Duplicated hybrid motif CVS48_RS08020 39facd872cb22e51d91e822b701c4f97 532 Gene3D G3DSA:2.70.70.10 392 532 2.2E-29 T 29-03-2018 CVS48_RS08020 39facd872cb22e51d91e822b701c4f97 532 Pfam PF01551 Peptidase family M23 433 526 2.8E-24 T 29-03-2018 IPR016047 Peptidase M23 CVS48_RS14030 83f87b9e0949fc5ecffc930a80f02ba8 74 Pfam PF04325 Protein of unknown function (DUF465) 19 66 2.6E-16 T 29-03-2018 IPR007420 Protein of unknown function DUF465 CVS48_RS09435 4023f1d58162dc76ad7cb97f4e74eaf6 492 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 479 7.8E-121 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS09435 4023f1d58162dc76ad7cb97f4e74eaf6 492 SUPERFAMILY SSF56954 4 35 4.45E-108 T 29-03-2018 CVS48_RS09435 4023f1d58162dc76ad7cb97f4e74eaf6 492 SUPERFAMILY SSF56954 65 484 4.45E-108 T 29-03-2018 CVS48_RS09435 4023f1d58162dc76ad7cb97f4e74eaf6 492 Pfam PF02321 Outer membrane efflux protein 74 266 3.5E-24 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS09435 4023f1d58162dc76ad7cb97f4e74eaf6 492 Pfam PF02321 Outer membrane efflux protein 290 465 4.6E-28 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS09435 4023f1d58162dc76ad7cb97f4e74eaf6 492 Gene3D G3DSA:1.20.1600.10 21 484 4.6E-106 T 29-03-2018 CVS48_RS11995 9c3f14b4e0ee02484421e772a1282293 271 Gene3D G3DSA:3.60.21.10 1 261 1.6E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS11995 9c3f14b4e0ee02484421e772a1282293 271 Pfam PF00149 Calcineurin-like phosphoesterase 2 232 3.1E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CVS48_RS11995 9c3f14b4e0ee02484421e772a1282293 271 SUPERFAMILY SSF56300 1 121 6.28E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS11995 9c3f14b4e0ee02484421e772a1282293 271 SUPERFAMILY SSF56300 168 252 6.28E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CVS48_RS23355 3bbcc7e83e8b65d55cc2f85482718a31 296 Gene3D G3DSA:1.10.3470.10 1 290 1.2E-38 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS23355 3bbcc7e83e8b65d55cc2f85482718a31 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 279 3.5E-31 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS01805 3cd86304758cc2d184ec3be4e84d1f6c 210 Pfam PF09335 SNARE associated Golgi protein 46 170 1.9E-21 T 29-03-2018 IPR032816 SNARE associated Golgi protein CVS48_RS16435 760c0eecad688b49e833e1600a33ddf4 357 Pfam PF01266 FAD dependent oxidoreductase 8 334 3.4E-46 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS16435 760c0eecad688b49e833e1600a33ddf4 357 Gene3D G3DSA:3.50.50.60 2 357 1.6E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16435 760c0eecad688b49e833e1600a33ddf4 357 SUPERFAMILY SSF51905 299 354 2.59E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS16435 760c0eecad688b49e833e1600a33ddf4 357 SUPERFAMILY SSF51905 7 213 2.59E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18660 40806d2729d17d6acae71b910cb36222 327 Gene3D G3DSA:3.40.190.10 127 256 7.0E-10 T 29-03-2018 CVS48_RS18660 40806d2729d17d6acae71b910cb36222 327 PIRSF PIRSF017082 1 327 3.2E-84 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS18660 40806d2729d17d6acae71b910cb36222 327 SUPERFAMILY SSF53850 121 289 9.77E-14 T 29-03-2018 CVS48_RS18660 40806d2729d17d6acae71b910cb36222 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 6.1E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS16985 e4371e07442f79a37abae32e5ba3ce8a 488 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 39 478 3.5E-193 T 29-03-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS16985 e4371e07442f79a37abae32e5ba3ce8a 488 SUPERFAMILY SSF52540 133 407 3.25E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16985 e4371e07442f79a37abae32e5ba3ce8a 488 SMART SM00382 198 385 6.8E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16985 e4371e07442f79a37abae32e5ba3ce8a 488 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 25 479 2.7E-175 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS16985 e4371e07442f79a37abae32e5ba3ce8a 488 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 186 401 4.5E-71 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS16985 e4371e07442f79a37abae32e5ba3ce8a 488 Gene3D G3DSA:3.40.50.300 107 401 2.7E-80 T 29-03-2018 CVS48_RS16985 e4371e07442f79a37abae32e5ba3ce8a 488 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 392 401 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CVS48_RS25700 1220e585470bea3aadc87613c58b274d 423 Pfam PF00534 Glycosyl transferases group 1 211 386 6.2E-44 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CVS48_RS25700 1220e585470bea3aadc87613c58b274d 423 Pfam PF13439 Glycosyltransferase Family 4 23 198 1.8E-34 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CVS48_RS25700 1220e585470bea3aadc87613c58b274d 423 Gene3D G3DSA:3.40.50.2000 210 392 6.9E-55 T 29-03-2018 CVS48_RS25700 1220e585470bea3aadc87613c58b274d 423 Gene3D G3DSA:3.40.50.2000 7 209 7.1E-25 T 29-03-2018 CVS48_RS25700 1220e585470bea3aadc87613c58b274d 423 SUPERFAMILY SSF53756 1 405 2.51E-94 T 29-03-2018 CVS48_RS18055 42f8a945dc06bda42f8e2d670831258d 246 Pfam PF00005 ABC transporter 21 169 9.5E-39 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS18055 42f8a945dc06bda42f8e2d670831258d 246 PIRSF PIRSF039085 2 246 6.2E-107 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CVS48_RS18055 42f8a945dc06bda42f8e2d670831258d 246 SUPERFAMILY SSF52540 5 240 2.54E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS18055 42f8a945dc06bda42f8e2d670831258d 246 SMART SM00382 30 218 3.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS18055 42f8a945dc06bda42f8e2d670831258d 246 Gene3D G3DSA:3.40.50.300 1 245 2.5E-76 T 29-03-2018 CVS48_RS18055 42f8a945dc06bda42f8e2d670831258d 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS28075 df845f1f8ac8416e86af7144e2cb2207 232 Gene3D G3DSA:3.40.1080.10 1 232 2.3E-100 T 29-03-2018 CVS48_RS28075 df845f1f8ac8416e86af7144e2cb2207 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 216 7.4E-81 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CVS48_RS28075 df845f1f8ac8416e86af7144e2cb2207 232 SMART SM00882 5 217 1.1E-94 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS28075 df845f1f8ac8416e86af7144e2cb2207 232 Pfam PF01144 Coenzyme A transferase 6 217 4.8E-81 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS28075 df845f1f8ac8416e86af7144e2cb2207 232 SUPERFAMILY SSF100950 2 226 1.31E-89 T 29-03-2018 CVS48_RS28075 df845f1f8ac8416e86af7144e2cb2207 232 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CVS48_RS06130 61b4c5b04f7d8a6da3cbbaebf3b33d8a 508 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 445 4.6E-140 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CVS48_RS03930 93c8d9c902cfff1436111e27c426573a 303 Gene3D G3DSA:3.90.850.10 58 303 8.5E-77 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS03930 93c8d9c902cfff1436111e27c426573a 303 SUPERFAMILY SSF56529 78 302 1.18E-71 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS03930 93c8d9c902cfff1436111e27c426573a 303 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 90 301 2.0E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS14120 bab6908cf794376da393cd3d2ef97401 331 SUPERFAMILY SSF50129 12 144 5.82E-34 T 29-03-2018 IPR011032 GroES-like CVS48_RS14120 bab6908cf794376da393cd3d2ef97401 331 SUPERFAMILY SSF51735 115 291 3.32E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS14120 bab6908cf794376da393cd3d2ef97401 331 SMART SM00829 14 327 2.0E-66 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CVS48_RS14120 bab6908cf794376da393cd3d2ef97401 331 Pfam PF00107 Zinc-binding dehydrogenase 155 273 1.3E-29 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CVS48_RS14120 bab6908cf794376da393cd3d2ef97401 331 Gene3D G3DSA:3.40.50.720 138 286 5.0E-35 T 29-03-2018 CVS48_RS14120 bab6908cf794376da393cd3d2ef97401 331 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 8 329 5.1E-137 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CVS48_RS14120 bab6908cf794376da393cd3d2ef97401 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 107 1.3E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CVS48_RS14120 bab6908cf794376da393cd3d2ef97401 331 Gene3D G3DSA:3.90.180.10 6 137 1.3E-31 T 29-03-2018 CVS48_RS14120 bab6908cf794376da393cd3d2ef97401 331 Gene3D G3DSA:3.90.180.10 287 330 3.7E-8 T 29-03-2018 CVS48_RS04945 2c22b2b00eb85c4123a73d78ca9f49ab 307 Pfam PF02104 SURF1 family 20 279 2.0E-28 T 29-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CVS48_RS22395 673f9d5f6b0cf3ef4dcc047a14f284a1 445 Gene3D G3DSA:1.20.1070.10 41 403 0.0021 T 29-03-2018 CVS48_RS22395 673f9d5f6b0cf3ef4dcc047a14f284a1 445 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 8 411 3.8E-80 T 29-03-2018 IPR005219 Conserved hypothetical protein CHP00155 CVS48_RS22395 673f9d5f6b0cf3ef4dcc047a14f284a1 445 Pfam PF04403 Paraquat-inducible protein A 47 198 2.5E-41 T 29-03-2018 IPR007498 Paraquat-inducible protein A CVS48_RS22395 673f9d5f6b0cf3ef4dcc047a14f284a1 445 Pfam PF04403 Paraquat-inducible protein A 257 411 3.0E-50 T 29-03-2018 IPR007498 Paraquat-inducible protein A CVS48_RS05040 0c1702a4785513e4a908af05961700a8 325 SUPERFAMILY SSF53850 112 286 6.65E-12 T 29-03-2018 CVS48_RS05040 0c1702a4785513e4a908af05961700a8 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 2.4E-89 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS05040 0c1702a4785513e4a908af05961700a8 325 Gene3D G3DSA:3.40.190.10 124 234 1.2E-9 T 29-03-2018 CVS48_RS05040 0c1702a4785513e4a908af05961700a8 325 PIRSF PIRSF017082 1 325 5.4E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS07525 d5d621c3950c262b623c4c9e0b60e94d 139 Pfam PF04143 Sulphur transport 49 131 4.8E-7 T 29-03-2018 IPR007272 Sulphur transport domain CVS48_RS03475 6a819134ff6c551cb506e86e88607ea1 306 Gene3D G3DSA:1.10.3470.10 1 298 1.4E-39 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS03475 6a819134ff6c551cb506e86e88607ea1 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 294 1.3E-34 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS22655 71ae73521bc323c6ee418b54dddc1ca3 266 Gene3D G3DSA:2.60.40.10 167 252 0.0039 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS22655 71ae73521bc323c6ee418b54dddc1ca3 266 Pfam PF10670 Domain of unknown function (DUF4198) 19 242 1.2E-69 T 29-03-2018 IPR019613 Protein of unknown function DUF4198 CVS48_RS22655 71ae73521bc323c6ee418b54dddc1ca3 266 Gene3D G3DSA:2.60.120.380 22 119 0.0069 T 29-03-2018 CVS48_RS22850 076f9352c1cade3be0af6cfa5c199733 145 SUPERFAMILY SSF55729 1 143 1.26E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS22850 076f9352c1cade3be0af6cfa5c199733 145 Pfam PF13673 Acetyltransferase (GNAT) domain 37 131 4.7E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CVS48_RS22850 076f9352c1cade3be0af6cfa5c199733 145 Gene3D G3DSA:3.40.630.30 1 145 5.3E-23 T 29-03-2018 CVS48_RS23515 d742123d1583f7c03990aafc876b39aa 526 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 508 3.2E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CVS48_RS23515 d742123d1583f7c03990aafc876b39aa 526 Gene3D G3DSA:3.30.300.30 419 526 4.4E-28 T 29-03-2018 CVS48_RS23515 d742123d1583f7c03990aafc876b39aa 526 Gene3D G3DSA:3.40.50.980 178 332 3.1E-36 T 29-03-2018 CVS48_RS23515 d742123d1583f7c03990aafc876b39aa 526 Gene3D G3DSA:3.40.50.980 2 177 2.9E-28 T 29-03-2018 CVS48_RS23515 d742123d1583f7c03990aafc876b39aa 526 SUPERFAMILY SSF56801 5 521 2.49E-113 T 29-03-2018 CVS48_RS23515 d742123d1583f7c03990aafc876b39aa 526 Pfam PF00501 AMP-binding enzyme 8 424 7.8E-64 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CVS48_RS23515 d742123d1583f7c03990aafc876b39aa 526 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site CVS48_RS23515 d742123d1583f7c03990aafc876b39aa 526 Gene3D G3DSA:2.30.38.10 333 417 1.2E-16 T 29-03-2018 CVS48_RS21080 ee9b8e0971b26ef5f9d3dde6d8c68e3d 535 Pfam PF08878 Domain of unknown function (DUF1837) 293 516 7.6E-18 T 29-03-2018 IPR014976 Protein of unknown function DUF1837 CVS48_RS21080 ee9b8e0971b26ef5f9d3dde6d8c68e3d 535 Pfam PF14130 Domain of unknown function (DUF4297) 5 209 7.1E-26 T 29-03-2018 IPR025382 Domain of unknown function DUF4297 CVS48_RS19795 41499d17e3f0d759374e5e8db90ea4fd 250 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 1 250 9.1E-50 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 CVS48_RS19795 41499d17e3f0d759374e5e8db90ea4fd 250 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 29 249 2.3E-51 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 CVS48_RS26765 1eb545b5d3129e784ae1c4c3325489c7 403 SUPERFAMILY SSF53822 30 401 5.38E-90 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS26765 1eb545b5d3129e784ae1c4c3325489c7 403 Pfam PF13458 Periplasmic binding protein 30 366 1.3E-85 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS26765 1eb545b5d3129e784ae1c4c3325489c7 403 Gene3D G3DSA:3.40.50.2300 155 311 2.6E-30 T 29-03-2018 CVS48_RS26765 1eb545b5d3129e784ae1c4c3325489c7 403 Gene3D G3DSA:3.40.50.2300 28 154 2.6E-15 T 29-03-2018 CVS48_RS21555 17f34c46a0755785373a7471fa31796d 104 Pfam PF01527 Transposase 3 62 3.0E-12 T 29-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CVS48_RS21555 17f34c46a0755785373a7471fa31796d 104 Gene3D G3DSA:1.10.10.10 1 57 4.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS21555 17f34c46a0755785373a7471fa31796d 104 SUPERFAMILY SSF46689 3 55 1.27E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CVS48_RS19610 68a29a6bf82a35325ad7cec2f8e73d07 169 Gene3D G3DSA:1.10.10.10 12 168 9.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19610 68a29a6bf82a35325ad7cec2f8e73d07 169 SUPERFAMILY SSF46785 22 148 2.47E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS19610 68a29a6bf82a35325ad7cec2f8e73d07 169 PIRSF PIRSF036158 1 169 5.1E-76 T 29-03-2018 IPR014601 Transcriptional regulator with MarR-type HTH domain CVS48_RS19610 68a29a6bf82a35325ad7cec2f8e73d07 169 Pfam PF13463 Winged helix DNA-binding domain 50 115 1.7E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS01970 97f76bcf5675ccc962abc56aec58b8ac 346 Pfam PF01863 Protein of unknown function DUF45 124 338 5.6E-59 T 29-03-2018 IPR002725 Protein of unknown function DUF45 CVS48_RS13305 157d626ae90f4a3a6c33eb25ee63a1b0 159 Pfam PF06754 Phosphonate metabolism protein PhnG 14 157 1.8E-49 T 29-03-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS13305 157d626ae90f4a3a6c33eb25ee63a1b0 159 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 13 158 5.6E-49 T 29-03-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS14240 108f4ac7d21e42d303ef5d031455c77a 96 SUPERFAMILY SSF54909 1 96 1.42E-30 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS14240 108f4ac7d21e42d303ef5d031455c77a 96 Gene3D G3DSA:3.30.70.100 1 96 2.1E-21 T 29-03-2018 CVS48_RS14240 108f4ac7d21e42d303ef5d031455c77a 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 6.3E-14 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CVS48_RS04160 d01cdad36ec30c7337adcf0149fed08c 181 Gene3D G3DSA:2.60.40.1090 26 181 9.7E-23 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CVS48_RS04160 d01cdad36ec30c7337adcf0149fed08c 181 SUPERFAMILY SSF49401 28 181 7.46E-19 T 29-03-2018 IPR008966 Adhesion domain CVS48_RS21720 e9a1c4591ee9497335685fb4c00eef09 240 SUPERFAMILY SSF102588 6 237 1.44E-48 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CVS48_RS21720 e9a1c4591ee9497335685fb4c00eef09 240 Gene3D G3DSA:3.40.50.10320 2 238 6.8E-32 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CVS48_RS21720 e9a1c4591ee9497335685fb4c00eef09 240 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 137 1.8E-19 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CVS48_RS17700 c9d3a7b7610de56b710611fe8613eab1 153 Pfam PF13211 Protein of unknown function (DUF4019) 38 139 1.8E-24 T 29-03-2018 IPR025091 Protein of unknown function DUF4019 CVS48_RS20010 e72ba748d2ea1e980de1a7065059a62e 102 Pfam PF09928 Predicted small integral membrane protein (DUF2160) 4 102 4.6E-37 T 29-03-2018 IPR018678 Protein of unknown function DUF2160, transmembrane CVS48_RS22435 3d2423e7e84bec973e74e8ae7252d729 478 Pfam PF00654 Voltage gated chloride channel 84 432 1.7E-70 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS22435 3d2423e7e84bec973e74e8ae7252d729 478 PRINTS PR00762 Chloride channel signature 400 419 3.9E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS22435 3d2423e7e84bec973e74e8ae7252d729 478 PRINTS PR00762 Chloride channel signature 352 372 3.9E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS22435 3d2423e7e84bec973e74e8ae7252d729 478 PRINTS PR00762 Chloride channel signature 128 147 3.9E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS22435 3d2423e7e84bec973e74e8ae7252d729 478 PRINTS PR00762 Chloride channel signature 94 111 3.9E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS22435 3d2423e7e84bec973e74e8ae7252d729 478 PRINTS PR00762 Chloride channel signature 382 398 3.9E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS22435 3d2423e7e84bec973e74e8ae7252d729 478 PRINTS PR00762 Chloride channel signature 184 203 3.9E-26 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS22435 3d2423e7e84bec973e74e8ae7252d729 478 Gene3D G3DSA:1.10.3080.10 14 453 7.3E-69 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS22435 3d2423e7e84bec973e74e8ae7252d729 478 SUPERFAMILY SSF81340 15 447 1.06E-84 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CVS48_RS08510 b9ce4b1b2d988abcaacb8e7d79148d45 134 Pfam PF13665 Domain of unknown function (DUF4150) 11 120 6.3E-35 T 29-03-2018 IPR025425 Domain of unknown function DUF4150 CVS48_RS18065 bb772a72c154136f422f317ecc62d30a 396 Gene3D G3DSA:1.10.3720.10 18 176 1.2E-18 T 29-03-2018 CVS48_RS18065 bb772a72c154136f422f317ecc62d30a 396 Gene3D G3DSA:1.10.3720.10 183 396 1.6E-36 T 29-03-2018 CVS48_RS18065 bb772a72c154136f422f317ecc62d30a 396 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 266 391 8.2E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18065 bb772a72c154136f422f317ecc62d30a 396 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 88 152 7.3E-16 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS18065 bb772a72c154136f422f317ecc62d30a 396 SUPERFAMILY SSF161098 183 200 1.57E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18065 bb772a72c154136f422f317ecc62d30a 396 SUPERFAMILY SSF161098 89 156 1.57E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18065 bb772a72c154136f422f317ecc62d30a 396 SUPERFAMILY SSF161098 189 377 1.96E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19865 8d2c59cadafecadc66f94c5a830a8456 257 SUPERFAMILY SSF161098 58 240 1.7E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19865 8d2c59cadafecadc66f94c5a830a8456 257 Gene3D G3DSA:1.10.3720.10 13 256 3.6E-25 T 29-03-2018 CVS48_RS19865 8d2c59cadafecadc66f94c5a830a8456 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 238 2.2E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS15530 bbf407c618173b63d9c43443a116333e 492 Gene3D G3DSA:1.20.1250.20 275 479 2.4E-20 T 29-03-2018 CVS48_RS15530 bbf407c618173b63d9c43443a116333e 492 SUPERFAMILY SSF103473 28 471 5.75E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS15530 bbf407c618173b63d9c43443a116333e 492 Gene3D G3DSA:1.20.1250.20 32 241 2.9E-32 T 29-03-2018 CVS48_RS15530 bbf407c618173b63d9c43443a116333e 492 Pfam PF07690 Major Facilitator Superfamily 52 365 4.4E-41 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS13760 579e372c8f566974169046779115b342 191 Pfam PF01126 Heme oxygenase 7 183 5.6E-11 T 29-03-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CVS48_RS13760 579e372c8f566974169046779115b342 191 SUPERFAMILY SSF48613 5 186 3.18E-35 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CVS48_RS13760 579e372c8f566974169046779115b342 191 Gene3D G3DSA:1.20.910.10 2 189 2.4E-26 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CVS48_RS28425 f7cdd2aa139d7de8d886c95914977e1e 169 Gene3D G3DSA:3.40.50.360 1 167 3.9E-25 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS28425 f7cdd2aa139d7de8d886c95914977e1e 169 SUPERFAMILY SSF52218 1 165 5.37E-28 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS09520 711304265941334cd473ab886729a4ac 161 Pfam PF03551 Transcriptional regulator PadR-like family 2 70 4.5E-16 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CVS48_RS09520 711304265941334cd473ab886729a4ac 161 SUPERFAMILY SSF46785 2 111 4.82E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS09520 711304265941334cd473ab886729a4ac 161 Gene3D G3DSA:1.10.10.10 1 94 4.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS16230 7661b73ca8873cde46b23e9796a1c15f 723 Pfam PF05506 Domain of unknown function (DUF756) 527 614 1.1E-25 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CVS48_RS16230 7661b73ca8873cde46b23e9796a1c15f 723 Pfam PF05506 Domain of unknown function (DUF756) 625 708 2.2E-22 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CVS48_RS16230 7661b73ca8873cde46b23e9796a1c15f 723 Pfam PF04185 Phosphoesterase family 54 454 1.1E-114 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 CVS48_RS16230 7661b73ca8873cde46b23e9796a1c15f 723 Gene3D G3DSA:3.40.720.10 131 457 2.5E-18 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS16230 7661b73ca8873cde46b23e9796a1c15f 723 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 12 722 4.8E-291 T 29-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CVS48_RS00765 d8a02907bef132b0f3d9ca1f69ca56bc 245 Gene3D G3DSA:3.40.30.10 146 207 0.0017 T 29-03-2018 CVS48_RS00765 d8a02907bef132b0f3d9ca1f69ca56bc 245 TIGRFAM TIGR03759 conj_TIGR03759: integrating conjugative element protein, PFL_4693 family 45 242 7.0E-86 T 29-03-2018 IPR022293 Integrating conjugative element protein, PFL4693 CVS48_RS28330 3cdade7098f2254856dff999cedadfcb 355 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 2 339 1.1E-114 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CVS48_RS28330 3cdade7098f2254856dff999cedadfcb 355 PIRSF PIRSF002465 1 338 3.2E-131 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CVS48_RS28330 3cdade7098f2254856dff999cedadfcb 355 Pfam PF02504 Fatty acid synthesis protein 2 322 1.1E-107 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CVS48_RS28330 3cdade7098f2254856dff999cedadfcb 355 SUPERFAMILY SSF53659 2 333 9.87E-106 T 29-03-2018 CVS48_RS28330 3cdade7098f2254856dff999cedadfcb 355 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 338 153.719 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CVS48_RS28330 3cdade7098f2254856dff999cedadfcb 355 Gene3D G3DSA:3.40.718.10 1 335 8.4E-107 T 29-03-2018 CVS48_RS23755 14528f04227e083d7b228f74781472e1 183 Gene3D G3DSA:3.90.79.10 33 183 2.3E-19 T 29-03-2018 CVS48_RS23755 14528f04227e083d7b228f74781472e1 183 PIRSF PIRSF037599 34 183 2.7E-51 T 29-03-2018 IPR033715 GDP-mannose mannosyl hydrolase GO:0008727 CVS48_RS23755 14528f04227e083d7b228f74781472e1 183 SUPERFAMILY SSF55811 38 178 1.9E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS23755 14528f04227e083d7b228f74781472e1 183 Pfam PF00293 NUDIX domain 51 171 5.0E-12 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CVS48_RS18255 b808610de3dcce4cf8b5331373dfc1c6 331 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 312 2.0E-88 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS18255 b808610de3dcce4cf8b5331373dfc1c6 331 PIRSF PIRSF006470 1 330 3.5E-98 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS18255 b808610de3dcce4cf8b5331373dfc1c6 331 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 34 290 2.1E-78 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS14070 45117ee6ff6ce7e036a21fca491593f7 348 Pfam PF00248 Aldo/keto reductase family 15 319 1.7E-81 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS14070 45117ee6ff6ce7e036a21fca491593f7 348 SUPERFAMILY SSF51430 1 319 8.25E-104 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS14070 45117ee6ff6ce7e036a21fca491593f7 348 Gene3D G3DSA:3.20.20.100 3 322 5.5E-101 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CVS48_RS05455 317b15ab7a350eea6bae5749e6bc5925 241 Pfam PF05036 Sporulation related domain 165 239 2.2E-15 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS05455 317b15ab7a350eea6bae5749e6bc5925 241 SUPERFAMILY SSF110997 166 240 6.02E-17 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS05455 317b15ab7a350eea6bae5749e6bc5925 241 Gene3D G3DSA:3.30.70.1070 162 241 3.0E-15 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CVS48_RS05955 6ffb11c6668796d5ed06d7a0c4ee61d1 387 SUPERFAMILY SSF51395 8 373 1.34E-104 T 29-03-2018 CVS48_RS05955 6ffb11c6668796d5ed06d7a0c4ee61d1 387 Pfam PF01070 FMN-dependent dehydrogenase 18 378 4.7E-133 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CVS48_RS05955 6ffb11c6668796d5ed06d7a0c4ee61d1 387 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 278 284 - T 29-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CVS48_RS05955 6ffb11c6668796d5ed06d7a0c4ee61d1 387 Gene3D G3DSA:3.20.20.70 7 380 2.1E-103 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS05955 6ffb11c6668796d5ed06d7a0c4ee61d1 387 PIRSF PIRSF000138 1 382 7.0E-123 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CVS48_RS20000 50fc9df6b7b27b67bd127f5b246ff1a4 328 SUPERFAMILY SSF53474 196 307 3.1E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS20000 50fc9df6b7b27b67bd127f5b246ff1a4 328 SUPERFAMILY SSF53474 21 158 3.1E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS20000 50fc9df6b7b27b67bd127f5b246ff1a4 328 Gene3D G3DSA:3.40.50.1820 1 324 3.3E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS20000 50fc9df6b7b27b67bd127f5b246ff1a4 328 Pfam PF12146 Serine aminopeptidase, S33 45 153 7.2E-8 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CVS48_RS20000 50fc9df6b7b27b67bd127f5b246ff1a4 328 PIRSF PIRSF031982 1 312 1.6E-82 T 29-03-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL CVS48_RS05520 5bd4e59ea2cdde31dd50cd871d4d0e20 535 SUPERFAMILY SSF52096 22 269 1.24E-70 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS05520 5bd4e59ea2cdde31dd50cd871d4d0e20 535 SUPERFAMILY SSF52096 277 535 1.2E-87 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS05520 5bd4e59ea2cdde31dd50cd871d4d0e20 535 Gene3D G3DSA:3.90.226.10 9 273 4.3E-69 T 29-03-2018 CVS48_RS05520 5bd4e59ea2cdde31dd50cd871d4d0e20 535 Pfam PF01039 Carboxyl transferase domain 48 526 5.7E-152 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CVS48_RS05520 5bd4e59ea2cdde31dd50cd871d4d0e20 535 Gene3D G3DSA:3.90.226.10 274 531 2.9E-72 T 29-03-2018 CVS48_RS05050 ebf14c78c43dda6b91fc174c71789a36 278 Gene3D G3DSA:3.40.50.300 10 273 1.2E-63 T 29-03-2018 CVS48_RS05050 ebf14c78c43dda6b91fc174c71789a36 278 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS05050 ebf14c78c43dda6b91fc174c71789a36 278 SUPERFAMILY SSF52540 13 242 3.64E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS05050 ebf14c78c43dda6b91fc174c71789a36 278 Pfam PF00005 ABC transporter 28 177 2.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05050 ebf14c78c43dda6b91fc174c71789a36 278 SMART SM00382 37 225 1.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS04250 d5255e47b96db8aa949e855889570af5 262 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 34.671 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CVS48_RS04250 d5255e47b96db8aa949e855889570af5 262 SUPERFAMILY SSF51366 12 261 1.29E-85 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CVS48_RS04250 d5255e47b96db8aa949e855889570af5 262 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 259 1.4E-91 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CVS48_RS04250 d5255e47b96db8aa949e855889570af5 262 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CVS48_RS04250 d5255e47b96db8aa949e855889570af5 262 Gene3D G3DSA:3.20.20.70 11 262 4.8E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS16865 cb2a7f249bc3ba398976dc802421c46e 139 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CVS48_RS16865 cb2a7f249bc3ba398976dc802421c46e 139 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 138 6.8E-53 T 29-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CVS48_RS16865 cb2a7f249bc3ba398976dc802421c46e 139 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 91 135 1.4E-14 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CVS48_RS16865 cb2a7f249bc3ba398976dc802421c46e 139 Pfam PF00460 Flagella basal body rod protein 7 37 6.5E-9 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CVS48_RS24160 7d9f0856be648e5a6350ab758c7da160 273 SUPERFAMILY SSF52540 27 253 1.5E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS24160 7d9f0856be648e5a6350ab758c7da160 273 Pfam PF00005 ABC transporter 43 181 3.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS24160 7d9f0856be648e5a6350ab758c7da160 273 SMART SM00382 51 232 3.9E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS24160 7d9f0856be648e5a6350ab758c7da160 273 Gene3D G3DSA:3.40.50.300 23 249 2.0E-58 T 29-03-2018 CVS48_RS25460 faa39fa720446f4d1edd79f32150fc36 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 18 136 1.2E-27 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CVS48_RS04760 f8d1f807d53c4396b4fea11c59d3c9e6 131 Gene3D G3DSA:3.30.1330.40 3 131 1.6E-31 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS04760 f8d1f807d53c4396b4fea11c59d3c9e6 131 Pfam PF01042 Endoribonuclease L-PSP 18 125 1.0E-27 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CVS48_RS04760 f8d1f807d53c4396b4fea11c59d3c9e6 131 SUPERFAMILY SSF55298 3 125 1.08E-33 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CVS48_RS08360 5030025445986e634a1fd2d34aa800d7 331 Pfam PF00437 Type II/IV secretion system protein 113 274 1.7E-14 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CVS48_RS08360 5030025445986e634a1fd2d34aa800d7 331 SUPERFAMILY SSF52540 15 239 3.32E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS08360 5030025445986e634a1fd2d34aa800d7 331 Gene3D G3DSA:3.40.50.300 123 330 0.0012 T 29-03-2018 CVS48_RS20150 d02694d0158ca6fe45cd7189e97741bb 687 Pfam PF04632 Fusaric acid resistance protein family 10 672 4.6E-194 T 29-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 CVS48_RS13570 d8d70493e366e9ed1d9adedfb7c39270 162 PIRSF PIRSF006181 5 162 1.0E-47 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CVS48_RS13570 d8d70493e366e9ed1d9adedfb7c39270 162 Pfam PF04073 Aminoacyl-tRNA editing domain 37 149 6.8E-27 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS13570 d8d70493e366e9ed1d9adedfb7c39270 162 SUPERFAMILY SSF55826 7 159 2.62E-43 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS13570 d8d70493e366e9ed1d9adedfb7c39270 162 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 157 9.4E-49 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CVS48_RS13570 d8d70493e366e9ed1d9adedfb7c39270 162 Gene3D G3DSA:3.90.960.10 1 161 1.9E-38 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CVS48_RS06455 f338ee05008334f3760cf82509e516ef 250 SUPERFAMILY SSF52540 6 235 1.57E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS06455 f338ee05008334f3760cf82509e516ef 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS06455 f338ee05008334f3760cf82509e516ef 250 Pfam PF00005 ABC transporter 22 172 2.8E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS06455 f338ee05008334f3760cf82509e516ef 250 Gene3D G3DSA:3.40.50.300 5 246 6.5E-52 T 29-03-2018 CVS48_RS06455 f338ee05008334f3760cf82509e516ef 250 SMART SM00382 31 221 6.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS24405 0bb989722c7778045e96b27e462f7f01 334 Gene3D G3DSA:3.15.30.10 7 205 8.7E-11 T 29-03-2018 CVS48_RS24405 0bb989722c7778045e96b27e462f7f01 334 Pfam PF03864 Phage major capsid protein E 12 332 8.2E-78 T 29-03-2018 IPR005564 Major capsid protein GpE GO:0019028 CVS48_RS11720 844e5f191abb367670427fc8cc22857f 134 Pfam PF11162 Protein of unknown function (DUF2946) 16 128 3.0E-6 T 29-03-2018 IPR021333 Protein of unknown function DUF2946 CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 Gene3D G3DSA:3.40.50.720 16 297 5.1E-64 T 29-03-2018 CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 43 278 3.4E-51 T 29-03-2018 CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 124 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 176 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 242 262 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 204 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 35 52 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 34 179 0.0014 T 29-03-2018 CVS48_RS15650 ab927baa2864c7dfb3468e9abc22ce96 317 SUPERFAMILY SSF51735 32 278 2.27E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS27155 6635a11f6eab8be147b00071753b0cca 133 Gene3D G3DSA:3.30.300.20 11 119 1.2E-25 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CVS48_RS27155 6635a11f6eab8be147b00071753b0cca 133 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 12 115 7.2E-20 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CVS48_RS27155 6635a11f6eab8be147b00071753b0cca 133 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 8 120 16.527 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CVS48_RS27155 6635a11f6eab8be147b00071753b0cca 133 SUPERFAMILY SSF89919 12 116 1.44E-24 T 29-03-2018 IPR023799 Ribosome-binding factor A domain CVS48_RS27155 6635a11f6eab8be147b00071753b0cca 133 Pfam PF02033 Ribosome-binding factor A 12 112 2.7E-23 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CVS48_RS27155 6635a11f6eab8be147b00071753b0cca 133 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 15 100 5.0E-40 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CVS48_RS24860 23814e0e2b1d71dabb12a0c1ea345014 79 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 9 63 5.7E-17 T 29-03-2018 IPR031856 Putative bacterial antitoxin YdaS CVS48_RS24860 23814e0e2b1d71dabb12a0c1ea345014 79 Gene3D G3DSA:1.10.260.40 1 61 4.0E-12 T 29-03-2018 CVS48_RS24860 23814e0e2b1d71dabb12a0c1ea345014 79 SUPERFAMILY SSF47413 7 63 1.52E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS16325 8c5968d0812b0630ab5e9e84117d4595 219 SUPERFAMILY SSF48452 73 190 4.22E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS16325 8c5968d0812b0630ab5e9e84117d4595 219 Gene3D G3DSA:1.25.40.10 154 216 7.7E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS16325 8c5968d0812b0630ab5e9e84117d4595 219 Pfam PF13181 Tetratricopeptide repeat 166 196 0.03 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CVS48_RS16325 8c5968d0812b0630ab5e9e84117d4595 219 Gene3D G3DSA:1.20.1250.10 32 153 2.9E-6 T 29-03-2018 CVS48_RS05310 0175b0e8984e10565c7fca2c9582dd5a 297 Pfam PF00892 EamA-like transporter family 4 134 4.0E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS05310 0175b0e8984e10565c7fca2c9582dd5a 297 Pfam PF00892 EamA-like transporter family 149 285 1.3E-10 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS05310 0175b0e8984e10565c7fca2c9582dd5a 297 SUPERFAMILY SSF103481 195 287 2.09E-9 T 29-03-2018 CVS48_RS05310 0175b0e8984e10565c7fca2c9582dd5a 297 SUPERFAMILY SSF103481 35 137 1.57E-14 T 29-03-2018 CVS48_RS26740 ef50b18b89be96203478ebf40e167738 625 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 283 3.3E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS26740 ef50b18b89be96203478ebf40e167738 625 Pfam PF02653 Branched-chain amino acid transport system / permease component 339 599 3.7E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS26740 ef50b18b89be96203478ebf40e167738 625 Gene3D G3DSA:1.10.3470.10 277 605 3.0E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS26740 ef50b18b89be96203478ebf40e167738 625 Gene3D G3DSA:1.10.3470.10 7 276 9.6E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS01295 c0262b1ddf1051b5b278616ac63c1b60 192 Pfam PF09361 Phasin protein 7 105 5.2E-24 T 29-03-2018 IPR018968 Phasin CVS48_RS01295 c0262b1ddf1051b5b278616ac63c1b60 192 TIGRFAM TIGR01841 phasin: phasin family protein 27 112 5.8E-21 T 29-03-2018 IPR010127 Phasin, subfamily 1 CVS48_RS27655 67c6b0d30d4f60468a2bb48c645e5383 287 Pfam PF03239 Iron permease FTR1 family 3 262 2.9E-23 T 29-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CVS48_RS16870 b1b9c0b6b36d72527d980aec269fddf5 232 Pfam PF13860 FlgD Ig-like domain 110 186 4.3E-22 T 29-03-2018 IPR025965 FlgD Ig-like domain CVS48_RS16870 b1b9c0b6b36d72527d980aec269fddf5 232 Pfam PF13861 FlgD Tudor-like domain 85 227 7.3E-13 T 29-03-2018 IPR025963 FlgD Tudor-like domain CVS48_RS16870 b1b9c0b6b36d72527d980aec269fddf5 232 Pfam PF03963 Flagellar hook capping protein - N-terminal region 5 75 1.7E-21 T 29-03-2018 IPR005648 Flagellar hook capping protein CVS48_RS08495 0953473f59470ec3fa31350695cdcc3a 227 Pfam PF09850 Type VI secretion system protein DotU 22 210 7.8E-37 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU CVS48_RS08495 0953473f59470ec3fa31350695cdcc3a 227 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 22 213 2.0E-32 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU CVS48_RS12470 8b674150fbd689309a93d3673b5dd156 167 Pfam PF04314 Copper chaperone PCu(A)C 34 137 1.1E-35 T 29-03-2018 IPR007410 Copper chaperone PCuAC CVS48_RS12470 8b674150fbd689309a93d3673b5dd156 167 SUPERFAMILY SSF110087 11 146 1.44E-42 T 29-03-2018 IPR007410 Copper chaperone PCuAC CVS48_RS02000 6c8e3cb1873db2d6a1fa895b6f03f246 380 SUPERFAMILY SSF110738 2 373 1.44E-129 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CVS48_RS02000 6c8e3cb1873db2d6a1fa895b6f03f246 380 PIRSF PIRSF006078 1 377 1.1E-130 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CVS48_RS02000 6c8e3cb1873db2d6a1fa895b6f03f246 380 Gene3D G3DSA:3.90.1510.10 42 274 3.8E-91 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CVS48_RS02000 6c8e3cb1873db2d6a1fa895b6f03f246 380 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 373 3.6E-146 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CVS48_RS02000 6c8e3cb1873db2d6a1fa895b6f03f246 380 Pfam PF02595 Glycerate kinase family 3 372 9.5E-144 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CVS48_RS28550 54a0f1d6711b7aa5dac17d2b949048ac 258 Pfam PF13616 PPIC-type PPIASE domain 119 220 3.6E-26 T 29-03-2018 CVS48_RS28550 54a0f1d6711b7aa5dac17d2b949048ac 258 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 157 178 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CVS48_RS28550 54a0f1d6711b7aa5dac17d2b949048ac 258 SUPERFAMILY SSF54534 101 219 1.05E-30 T 29-03-2018 CVS48_RS28550 54a0f1d6711b7aa5dac17d2b949048ac 258 Gene3D G3DSA:3.10.50.40 119 243 2.9E-38 T 29-03-2018 CVS48_RS08345 f5085e32388e99b07c23ccd8c04a885a 153 Pfam PF12101 Protein of unknown function (DUF3577) 4 136 3.8E-35 T 29-03-2018 IPR021960 Protein of unknown function DUF3577 CVS48_RS23190 8b1b96a0ac637c221d917652dc6a1f3f 249 Gene3D G3DSA:3.40.50.1820 2 247 6.9E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS23190 8b1b96a0ac637c221d917652dc6a1f3f 249 SUPERFAMILY SSF53474 3 244 2.32E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS23190 8b1b96a0ac637c221d917652dc6a1f3f 249 Pfam PF12697 Alpha/beta hydrolase family 8 230 3.9E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CVS48_RS17300 a403d80132b51f20680cfbbde28984f2 349 Gene3D G3DSA:1.20.272.10 238 348 1.1E-8 T 29-03-2018 CVS48_RS17300 a403d80132b51f20680cfbbde28984f2 349 Gene3D G3DSA:3.40.50.300 11 189 2.7E-21 T 29-03-2018 CVS48_RS17300 a403d80132b51f20680cfbbde28984f2 349 Pfam PF13177 DNA polymerase III, delta subunit 21 192 1.7E-37 T 29-03-2018 CVS48_RS17300 a403d80132b51f20680cfbbde28984f2 349 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 20 225 1.3E-63 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CVS48_RS17300 a403d80132b51f20680cfbbde28984f2 349 SUPERFAMILY SSF52540 9 83 4.47E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS17300 a403d80132b51f20680cfbbde28984f2 349 SUPERFAMILY SSF52540 110 230 4.47E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS15765 3b76a38a647b7db014bd6e3752c056d8 105 Pfam PF03927 NapD protein 16 90 2.2E-27 T 29-03-2018 IPR005623 Chaperone NapD, nitrate reductase assembly CVS48_RS26045 0104c36c564d21b0dabde54fe98d0053 90 Gene3D G3DSA:3.40.630.30 1 90 7.0E-18 T 29-03-2018 CVS48_RS26045 0104c36c564d21b0dabde54fe98d0053 90 SUPERFAMILY SSF55729 2 89 5.31E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS26045 0104c36c564d21b0dabde54fe98d0053 90 Pfam PF14542 GCN5-related N-acetyl-transferase 12 88 4.6E-26 T 29-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CVS48_RS28845 2c88fc76587167a31d7a226522993ba2 305 Pfam PF05661 Protein of unknown function (DUF808) 4 293 2.6E-116 T 29-03-2018 IPR008526 Inner membrane protein YedI CVS48_RS28845 2c88fc76587167a31d7a226522993ba2 305 PIRSF PIRSF016660 1 305 3.4E-124 T 29-03-2018 IPR008526 Inner membrane protein YedI CVS48_RS27480 d2114a9930250a2620585caa425814e0 404 Gene3D G3DSA:1.25.40.10 38 258 3.1E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS27480 d2114a9930250a2620585caa425814e0 404 SUPERFAMILY SSF48452 40 171 5.36E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS27480 d2114a9930250a2620585caa425814e0 404 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 402 32.778 T 29-03-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 CVS48_RS22820 5bda1eadccf5281de6d712076222992c 170 SUPERFAMILY SSF46785 24 159 4.48E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22820 5bda1eadccf5281de6d712076222992c 170 Pfam PF13463 Winged helix DNA-binding domain 52 117 1.2E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS22820 5bda1eadccf5281de6d712076222992c 170 Gene3D G3DSA:1.10.10.10 22 167 5.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22820 5bda1eadccf5281de6d712076222992c 170 PIRSF PIRSF036158 1 170 1.1E-71 T 29-03-2018 IPR014601 Transcriptional regulator with MarR-type HTH domain CVS48_RS20430 37077eec66998b424da7ec2c5651021b 83 SUPERFAMILY SSF47598 3 67 6.23E-21 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CVS48_RS20430 37077eec66998b424da7ec2c5651021b 83 Pfam PF03869 Arc-like DNA binding domain 10 46 4.2E-6 T 29-03-2018 IPR005569 Arc-like DNA binding domain GO:0003677 CVS48_RS20430 37077eec66998b424da7ec2c5651021b 83 Gene3D G3DSA:1.10.1220.10 1 73 2.3E-14 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CVS48_RS08945 67b8b60b480118a7acc7a3dc5fd0dabb 400 SUPERFAMILY SSF53822 31 396 3.7E-74 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS08945 67b8b60b480118a7acc7a3dc5fd0dabb 400 Gene3D G3DSA:3.40.50.2300 270 370 2.9E-6 T 29-03-2018 CVS48_RS08945 67b8b60b480118a7acc7a3dc5fd0dabb 400 Gene3D G3DSA:3.40.50.2300 24 251 1.2E-40 T 29-03-2018 CVS48_RS08945 67b8b60b480118a7acc7a3dc5fd0dabb 400 Pfam PF13458 Periplasmic binding protein 31 381 2.5E-61 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS19225 350eb894c9c00ec38f348237876b9821 125 Pfam PF04241 Protein of unknown function (DUF423) 20 106 2.0E-28 T 29-03-2018 IPR006696 Protein of unknown function DUF423 CVS48_RS17390 c73ff7e30ad0ddd5095c4fb92d776ec8 110 SUPERFAMILY SSF48452 6 78 6.12E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS17390 c73ff7e30ad0ddd5095c4fb92d776ec8 110 Gene3D G3DSA:1.25.40.10 1 110 1.8E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS17390 c73ff7e30ad0ddd5095c4fb92d776ec8 110 Pfam PF13432 Tetratricopeptide repeat 24 83 8.2E-6 T 29-03-2018 CVS48_RS25545 35f629bc82a21da90e1a6ecf331872e1 815 SUPERFAMILY SSF89796 405 806 9.03E-104 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS25545 35f629bc82a21da90e1a6ecf331872e1 815 SUPERFAMILY SSF89796 9 381 1.05E-62 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS25545 35f629bc82a21da90e1a6ecf331872e1 815 Gene3D G3DSA:3.40.50.10540 401 815 7.1E-109 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS25545 35f629bc82a21da90e1a6ecf331872e1 815 Gene3D G3DSA:3.40.50.10540 4 391 2.2E-62 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS25545 35f629bc82a21da90e1a6ecf331872e1 815 Pfam PF02515 CoA-transferase family III 11 361 3.3E-52 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS25545 35f629bc82a21da90e1a6ecf331872e1 815 Pfam PF02515 CoA-transferase family III 407 782 2.1E-102 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS09115 698c3e53fa14eaee49b521c29de04433 264 Pfam PF00285 Citrate synthase, C-terminal domain 35 232 1.7E-25 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS09115 698c3e53fa14eaee49b521c29de04433 264 Gene3D G3DSA:1.10.580.10 8 139 4.8E-18 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CVS48_RS09115 698c3e53fa14eaee49b521c29de04433 264 Gene3D G3DSA:1.10.580.10 140 235 1.3E-5 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CVS48_RS09115 698c3e53fa14eaee49b521c29de04433 264 SUPERFAMILY SSF48256 29 243 1.1E-39 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CVS48_RS22020 b6f564c3d39cd5e1b71b63ec589b9b1c 102 Gene3D G3DSA:1.10.10.10 6 89 2.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS22020 b6f564c3d39cd5e1b71b63ec589b9b1c 102 Pfam PF10711 Hypothetical protein (DUF2513) 3 89 1.7E-8 T 29-03-2018 IPR019650 Protein of unknown function DUF2513 CVS48_RS03340 fe58d6fbdf20e2c673f665da04e067e7 269 Gene3D G3DSA:3.40.1190.20 4 262 8.5E-24 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS03340 fe58d6fbdf20e2c673f665da04e067e7 269 SUPERFAMILY SSF53613 5 265 2.8E-36 T 29-03-2018 IPR029056 Ribokinase-like CVS48_RS03340 fe58d6fbdf20e2c673f665da04e067e7 269 Pfam PF08543 Phosphomethylpyrimidine kinase 16 259 1.3E-33 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CVS48_RS05430 0626d50ae235db69c9de7fb265920cd8 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 288 7.3E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05430 0626d50ae235db69c9de7fb265920cd8 291 Gene3D G3DSA:1.20.58.370 3 39 2.0E-5 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CVS48_RS05430 0626d50ae235db69c9de7fb265920cd8 291 Gene3D G3DSA:1.10.3720.10 58 289 2.5E-45 T 29-03-2018 CVS48_RS05430 0626d50ae235db69c9de7fb265920cd8 291 SUPERFAMILY SSF161098 52 277 1.83E-58 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS06305 63ea72a3a7c56d37957b487454aa3745 369 Pfam PF01476 LysM domain 36 82 2.6E-7 T 29-03-2018 IPR018392 LysM domain CVS48_RS06305 63ea72a3a7c56d37957b487454aa3745 369 SMART SM00257 35 82 9.9E-5 T 29-03-2018 IPR018392 LysM domain CVS48_RS06305 63ea72a3a7c56d37957b487454aa3745 369 Pfam PF04773 FecR protein 120 221 2.9E-15 T 29-03-2018 IPR006860 FecR protein CVS48_RS06305 63ea72a3a7c56d37957b487454aa3745 369 Gene3D G3DSA:3.10.350.10 34 84 7.7E-8 T 29-03-2018 CVS48_RS06305 63ea72a3a7c56d37957b487454aa3745 369 SUPERFAMILY SSF54106 35 82 2.75E-6 T 29-03-2018 IPR018392 LysM domain CVS48_RS06305 63ea72a3a7c56d37957b487454aa3745 369 PIRSF PIRSF029644 1 364 4.2E-106 T 29-03-2018 IPR016930 Uncharacterised conserved protein UCP029644, LysM, PA4035 CVS48_RS02130 6dadf0e7ab4d6301796b3bb291d9ea86 448 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 6 447 2.2E-141 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 CVS48_RS02130 6dadf0e7ab4d6301796b3bb291d9ea86 448 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 446 6.2E-137 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 CVS48_RS06380 c62170d2262ccbeda4044a159f03d6a4 255 Gene3D G3DSA:1.10.3720.10 4 248 4.4E-23 T 29-03-2018 CVS48_RS06380 c62170d2262ccbeda4044a159f03d6a4 255 SUPERFAMILY SSF161098 51 231 6.54E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS06380 c62170d2262ccbeda4044a159f03d6a4 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 244 5.4E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19185 7ec277c51c2315164b4498bbb9a43312 398 Gene3D G3DSA:1.20.1250.20 13 197 1.3E-22 T 29-03-2018 CVS48_RS19185 7ec277c51c2315164b4498bbb9a43312 398 Gene3D G3DSA:1.20.1250.20 204 398 4.7E-23 T 29-03-2018 CVS48_RS19185 7ec277c51c2315164b4498bbb9a43312 398 Pfam PF07690 Major Facilitator Superfamily 20 233 7.1E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS19185 7ec277c51c2315164b4498bbb9a43312 398 SUPERFAMILY SSF103473 12 390 1.7E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 Pfam PF00106 short chain dehydrogenase 5 188 1.5E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 3.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 3.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 SUPERFAMILY SSF51735 5 247 4.68E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CVS48_RS05630 9de4550720cc974f7e0745d51c775e06 276 Gene3D G3DSA:3.40.50.720 4 276 4.5E-62 T 29-03-2018 CVS48_RS26560 515007dc0a892890f17cf6ab09da5592 363 Pfam PF01594 AI-2E family transporter 15 340 1.0E-52 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CVS48_RS02605 9b9955ef0761b8035fa10108b7069ea3 103 Pfam PF05164 Cell division protein ZapA 4 89 6.4E-19 T 29-03-2018 IPR007838 Cell division protein ZapA-like CVS48_RS02605 9b9955ef0761b8035fa10108b7069ea3 103 SUPERFAMILY SSF102829 3 97 1.44E-20 T 29-03-2018 IPR007838 Cell division protein ZapA-like CVS48_RS18050 9d1a1588b3721461b4a0bdf4016666c4 362 Pfam PF13609 Gram-negative porin 10 341 3.4E-41 T 29-03-2018 CVS48_RS18050 9d1a1588b3721461b4a0bdf4016666c4 362 Gene3D G3DSA:2.40.160.10 10 361 3.2E-54 T 29-03-2018 CVS48_RS18050 9d1a1588b3721461b4a0bdf4016666c4 362 PRINTS PR00184 Neisseria sp. porin signature 316 340 1.9E-6 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS18050 9d1a1588b3721461b4a0bdf4016666c4 362 PRINTS PR00184 Neisseria sp. porin signature 55 80 1.9E-6 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS18050 9d1a1588b3721461b4a0bdf4016666c4 362 PRINTS PR00184 Neisseria sp. porin signature 275 301 1.9E-6 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CVS48_RS18050 9d1a1588b3721461b4a0bdf4016666c4 362 SUPERFAMILY SSF56935 23 361 5.49E-58 T 29-03-2018 CVS48_RS20155 be79fc119d85e8186aef038e6b1155a8 70 Pfam PF07869 Protein of unknown function (DUF1656) 4 58 8.7E-23 T 29-03-2018 IPR012451 Protein of unknown function DUF1656 CVS48_RS16120 042b93df1c56bdd104088defeea8166b 457 Gene3D G3DSA:2.30.30.60 204 254 1.9E-10 T 29-03-2018 CVS48_RS16120 042b93df1c56bdd104088defeea8166b 457 Pfam PF00924 Mechanosensitive ion channel 148 399 9.3E-43 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CVS48_RS16120 042b93df1c56bdd104088defeea8166b 457 SUPERFAMILY SSF50182 187 254 1.14E-10 T 29-03-2018 IPR010920 LSM domain CVS48_RS05480 4de68c7e91581fca485fe4b3b87ae517 240 Pfam PF00881 Nitroreductase family 24 214 1.9E-27 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CVS48_RS05480 4de68c7e91581fca485fe4b3b87ae517 240 SUPERFAMILY SSF55469 21 238 1.07E-43 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CVS48_RS05480 4de68c7e91581fca485fe4b3b87ae517 240 Gene3D G3DSA:3.40.109.10 3 235 1.9E-47 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CVS48_RS13670 8e9eecf69fee4d2c327631c27e6ff3c7 106 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 93 1.5E-10 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CVS48_RS13670 8e9eecf69fee4d2c327631c27e6ff3c7 106 Gene3D G3DSA:3.30.2310.20 1 101 7.9E-11 T 29-03-2018 CVS48_RS10130 349bf17fa1b9c217f6d556cddfc41f37 157 Gene3D G3DSA:3.30.2310.20 3 130 1.3E-5 T 29-03-2018 CVS48_RS10130 349bf17fa1b9c217f6d556cddfc41f37 157 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 15 151 1.2E-60 T 29-03-2018 IPR021679 Toxin endonuclease, YhaV GO:0004540|GO:0110001 CVS48_RS25480 6bd0c99ff3790910d88e405afb153978 323 Pfam PF04773 FecR protein 123 210 2.8E-6 T 29-03-2018 IPR006860 FecR protein CVS48_RS25480 6bd0c99ff3790910d88e405afb153978 323 PIRSF PIRSF018266 10 322 2.0E-51 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS25480 6bd0c99ff3790910d88e405afb153978 323 Pfam PF16220 Domain of unknown function (DUF4880) 20 59 5.0E-10 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS01990 6eb350ea39418de7481f47929d0e01ab 409 PIRSF PIRSF036542 1 409 6.6E-207 T 29-03-2018 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB CVS48_RS01990 6eb350ea39418de7481f47929d0e01ab 409 Pfam PF07670 Nucleoside recognition 52 158 3.7E-8 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CVS48_RS21745 6fc583500666b3c4b110475eba2ac250 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS21745 6fc583500666b3c4b110475eba2ac250 252 SUPERFAMILY SSF52540 2 225 2.89E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21745 6fc583500666b3c4b110475eba2ac250 252 Pfam PF00005 ABC transporter 18 164 1.5E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS21745 6fc583500666b3c4b110475eba2ac250 252 Gene3D G3DSA:3.40.50.300 1 229 3.7E-63 T 29-03-2018 CVS48_RS21745 6fc583500666b3c4b110475eba2ac250 252 SMART SM00382 26 213 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS16195 598cdc2b185a3922a65c2211908cf939 340 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 255 1.0E-43 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CVS48_RS16195 598cdc2b185a3922a65c2211908cf939 340 SUPERFAMILY SSF51735 12 336 1.22E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS16195 598cdc2b185a3922a65c2211908cf939 340 Gene3D G3DSA:3.40.50.720 12 339 1.4E-62 T 29-03-2018 CVS48_RS18105 c630a6ee2898641d4c8404167fc5e39d 209 Gene3D G3DSA:3.40.50.180 16 208 8.4E-64 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS18105 c630a6ee2898641d4c8404167fc5e39d 209 Pfam PF01339 CheB methylesterase 24 200 2.4E-54 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS18105 c630a6ee2898641d4c8404167fc5e39d 209 SUPERFAMILY SSF52738 19 203 4.32E-55 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CVS48_RS23015 13aecbc5290e24280a5c0dad89355da4 365 SUPERFAMILY SSF51735 1 143 2.1E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS23015 13aecbc5290e24280a5c0dad89355da4 365 Gene3D G3DSA:3.40.50.720 1 188 4.3E-21 T 29-03-2018 CVS48_RS23015 13aecbc5290e24280a5c0dad89355da4 365 SUPERFAMILY SSF48179 191 361 5.44E-46 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CVS48_RS23015 13aecbc5290e24280a5c0dad89355da4 365 Gene3D G3DSA:1.10.1040.10 197 351 1.6E-36 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CVS48_RS23015 13aecbc5290e24280a5c0dad89355da4 365 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 187 333 1.3E-29 T 29-03-2018 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 CVS48_RS00445 a77edc04fc98212eceacd84bc547697f 299 Hamap MF_00361 NAD kinase [nadK]. 4 288 32.554 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CVS48_RS00445 a77edc04fc98212eceacd84bc547697f 299 Pfam PF01513 ATP-NAD kinase 52 272 6.9E-55 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CVS48_RS00445 a77edc04fc98212eceacd84bc547697f 299 SUPERFAMILY SSF111331 5 290 1.13E-86 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CVS48_RS00445 a77edc04fc98212eceacd84bc547697f 299 Gene3D G3DSA:3.40.50.10330 1 139 2.0E-35 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CVS48_RS00445 a77edc04fc98212eceacd84bc547697f 299 Gene3D G3DSA:2.60.200.30 140 265 9.4E-37 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CVS48_RS28290 6a5fd5543c7e7076b85caa9b087601eb 171 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 16 79 6.0E-12 T 29-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 CVS48_RS28290 6a5fd5543c7e7076b85caa9b087601eb 171 SUPERFAMILY SSF89069 15 78 1.31E-12 T 29-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 CVS48_RS19105 05d2dd80467ba545fd04f93a636fc90b 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 1.1E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS19105 05d2dd80467ba545fd04f93a636fc90b 135 SUPERFAMILY SSF54593 2 130 8.38E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS19105 05d2dd80467ba545fd04f93a636fc90b 135 Gene3D G3DSA:3.10.180.10 1 135 9.2E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS25935 1d4f592ea4b51da37764832556b47e14 384 Pfam PF07690 Major Facilitator Superfamily 5 344 3.8E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS25935 1d4f592ea4b51da37764832556b47e14 384 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 2 373 5.0E-92 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CVS48_RS25935 1d4f592ea4b51da37764832556b47e14 384 SUPERFAMILY SSF103473 3 372 9.81E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS25935 1d4f592ea4b51da37764832556b47e14 384 Gene3D G3DSA:1.20.1250.20 185 376 3.8E-11 T 29-03-2018 CVS48_RS25935 1d4f592ea4b51da37764832556b47e14 384 Gene3D G3DSA:1.20.1250.20 1 179 7.6E-30 T 29-03-2018 CVS48_RS16910 e27b19694c3fcff4858ba2107ebc3dbb 419 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 416 3.2E-80 T 29-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 CVS48_RS16910 e27b19694c3fcff4858ba2107ebc3dbb 419 Gene3D G3DSA:1.20.1330.10 38 394 7.0E-23 T 29-03-2018 CVS48_RS16910 e27b19694c3fcff4858ba2107ebc3dbb 419 SUPERFAMILY SSF64518 1 417 6.54E-64 T 29-03-2018 CVS48_RS16910 e27b19694c3fcff4858ba2107ebc3dbb 419 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 140 6.1E-19 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CVS48_RS02070 37536f13b24e0fd4c505545b6fea59f7 288 Pfam PF13503 Domain of unknown function (DUF4123) 16 131 5.3E-5 T 29-03-2018 IPR025391 Domain of unknown function DUF4123 CVS48_RS23170 1b38f818574c47c790dca8b4ad934049 57 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 3 45 6.5E-19 T 29-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type CVS48_RS23170 1b38f818574c47c790dca8b4ad934049 57 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 47 3.5E-15 T 29-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type CVS48_RS14035 bc8361c04dfc2130272043fb14b54196 382 Pfam PF04116 Fatty acid hydroxylase superfamily 213 346 5.0E-28 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CVS48_RS08230 868c0a135d92ebac4ccae5d3f900fe8f 96 Pfam PF13663 Domain of unknown function (DUF4148) 4 54 2.0E-8 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS21125 a917f16f33340b597aaaeb473861b047 255 SUPERFAMILY SSF51621 2 253 4.89E-76 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS21125 a917f16f33340b597aaaeb473861b047 255 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 241 3.5E-53 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CVS48_RS21125 a917f16f33340b597aaaeb473861b047 255 Gene3D G3DSA:3.20.20.60 2 254 4.5E-41 T 29-03-2018 CVS48_RS25500 44ce5abc2674b7d9d21ac6b92913571d 121 SUPERFAMILY SSF51182 18 118 1.01E-14 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS25500 44ce5abc2674b7d9d21ac6b92913571d 121 Gene3D G3DSA:2.60.120.10 12 121 7.5E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS25500 44ce5abc2674b7d9d21ac6b92913571d 121 Pfam PF05899 Protein of unknown function (DUF861) 42 115 1.6E-14 T 29-03-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 CVS48_RS22790 77ab140d671615c19f7b8265e3befa07 110 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 46 1.8E-14 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CVS48_RS22790 77ab140d671615c19f7b8265e3befa07 110 Pfam PF09723 Zinc ribbon domain 1 40 2.4E-10 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CVS48_RS22790 77ab140d671615c19f7b8265e3befa07 110 SMART SM00834 1 41 9.8E-13 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CVS48_RS18570 6a99c0b1f75475d9d8135fa6a159b6a8 174 Gene3D G3DSA:3.40.50.360 1 171 1.7E-9 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS18570 6a99c0b1f75475d9d8135fa6a159b6a8 174 SUPERFAMILY SSF52218 2 125 1.29E-10 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS21210 e52805cf14d9112cf2c3fc30c900b96c 433 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 202 427 4.1E-32 T 29-03-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal CVS48_RS21210 e52805cf14d9112cf2c3fc30c900b96c 433 PIRSF PIRSF016521 3 432 2.1E-107 T 29-03-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 CVS48_RS21210 e52805cf14d9112cf2c3fc30c900b96c 433 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 17 135 1.2E-22 T 29-03-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase CVS48_RS21210 e52805cf14d9112cf2c3fc30c900b96c 433 Gene3D G3DSA:3.40.50.1820 129 426 3.4E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21210 e52805cf14d9112cf2c3fc30c900b96c 433 SUPERFAMILY SSF53474 291 384 8.34E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21210 e52805cf14d9112cf2c3fc30c900b96c 433 SUPERFAMILY SSF53474 121 263 8.34E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS24540 c9bd13e07f17102b3ba6c2c3b49c198d 137 Gene3D G3DSA:3.40.1350.10 1 74 2.9E-5 T 29-03-2018 CVS48_RS01800 677d8e34b1ecb38f65a2e8afa314d4b0 411 SMART SM00646 243 398 9.4E-59 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CVS48_RS01800 677d8e34b1ecb38f65a2e8afa314d4b0 411 Pfam PF11741 AMIN domain 3 106 3.1E-24 T 29-03-2018 IPR021731 AMIN domain CVS48_RS01800 677d8e34b1ecb38f65a2e8afa314d4b0 411 SUPERFAMILY SSF53187 325 401 5.96E-55 T 29-03-2018 CVS48_RS01800 677d8e34b1ecb38f65a2e8afa314d4b0 411 SUPERFAMILY SSF53187 181 277 5.96E-55 T 29-03-2018 CVS48_RS01800 677d8e34b1ecb38f65a2e8afa314d4b0 411 Gene3D G3DSA:3.40.630.40 178 405 5.6E-56 T 29-03-2018 CVS48_RS01800 677d8e34b1ecb38f65a2e8afa314d4b0 411 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 183 398 2.4E-49 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CVS48_RS02145 62b19548fbba23d0f2b7b1e29b9f7940 166 Gene3D G3DSA:2.60.40.1120 78 166 0.0025 T 29-03-2018 CVS48_RS07075 3d154dcadde64fcf364032963ce0409c 355 Pfam PF03102 NeuB family 23 290 2.1E-92 T 29-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 CVS48_RS07075 3d154dcadde64fcf364032963ce0409c 355 TIGRFAM TIGR03569 NeuB_NnaB: N-acetylneuraminate synthase 3 352 1.2E-136 T 29-03-2018 IPR020007 N-acetylneuraminate synthase KEGG: 00520+2.5.1.101|KEGG: 00900+2.5.1.10|MetaCyc: PWY-5123|MetaCyc: PWY-6749|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7131|MetaCyc: PWY-7721|MetaCyc: PWY-7736 CVS48_RS07075 3d154dcadde64fcf364032963ce0409c 355 Gene3D G3DSA:3.90.1210.10 294 355 1.4E-10 T 29-03-2018 CVS48_RS07075 3d154dcadde64fcf364032963ce0409c 355 SUPERFAMILY SSF51569 2 158 4.4E-73 T 29-03-2018 CVS48_RS07075 3d154dcadde64fcf364032963ce0409c 355 SUPERFAMILY SSF51569 186 313 4.4E-73 T 29-03-2018 CVS48_RS07075 3d154dcadde64fcf364032963ce0409c 355 Gene3D G3DSA:3.20.20.70 1 290 8.9E-82 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS07075 3d154dcadde64fcf364032963ce0409c 355 SUPERFAMILY SSF51269 296 353 1.32E-10 T 29-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 CVS48_RS24670 ee389a493bff6f30f4d273d6602b18d7 376 Pfam PF06804 NlpB/DapX lipoprotein 42 374 8.0E-46 T 29-03-2018 IPR010653 NlpB/DapX lipoprotein CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 Gene3D G3DSA:2.160.20.80 6 78 6.2E-11 T 29-03-2018 CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 Gene3D G3DSA:2.160.20.80 187 264 4.0E-17 T 29-03-2018 CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 Pfam PF00805 Pentapeptide repeats (8 copies) 21 55 5.6E-8 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 Pfam PF00805 Pentapeptide repeats (8 copies) 274 311 5.4E-8 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 Pfam PF13599 Pentapeptide repeats (9 copies) 191 266 5.0E-9 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 Pfam PF13599 Pentapeptide repeats (9 copies) 73 145 4.5E-8 T 29-03-2018 IPR001646 Pentapeptide repeat CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 SUPERFAMILY SSF141571 7 174 6.57E-33 T 29-03-2018 CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 SUPERFAMILY SSF141571 151 317 1.5E-32 T 29-03-2018 CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 Gene3D G3DSA:2.160.10.20 265 330 6.0E-15 T 29-03-2018 CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 Gene3D G3DSA:2.160.10.20 79 141 4.2E-13 T 29-03-2018 CVS48_RS06630 1892b8279e1d1ec5ec667819ae40f3e2 352 Gene3D G3DSA:2.160.10.20 142 186 3.0E-7 T 29-03-2018 CVS48_RS05825 6c830797bbf4968c5e7166295eddcbb0 316 Gene3D G3DSA:1.10.3470.10 4 305 2.3E-35 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS05825 6c830797bbf4968c5e7166295eddcbb0 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 15 293 1.3E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS19925 b04a023d934a24344ca5b64c5a589e90 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 109 1.4E-27 T 29-03-2018 CVS48_RS18815 f8854c508f8107bbb277451ced34fcc1 432 Pfam PF13520 Amino acid permease 3 400 1.1E-39 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CVS48_RS18815 f8854c508f8107bbb277451ced34fcc1 432 PIRSF PIRSF006060 1 431 7.9E-64 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CVS48_RS24745 d8e73e160f29fd6103cf3ab3beed72d2 156 Gene3D G3DSA:1.20.1290.10 1 154 8.3E-36 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS24745 d8e73e160f29fd6103cf3ab3beed72d2 156 SUPERFAMILY SSF69118 6 145 2.21E-42 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS24745 d8e73e160f29fd6103cf3ab3beed72d2 156 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 76 2.2E-14 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS24745 d8e73e160f29fd6103cf3ab3beed72d2 156 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 94 4.3E-16 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS03130 be26ff6c1bea6db5e3c56f869c07138c 186 Pfam PF02325 YGGT family 12 81 1.4E-14 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 CVS48_RS03130 be26ff6c1bea6db5e3c56f869c07138c 186 Pfam PF02325 YGGT family 110 176 1.2E-15 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 CVS48_RS28285 2f431e6be23cbef0a3e21014b49725dd 348 Pfam PF17188 MucB/RseB C-terminal domain 245 339 1.8E-25 T 29-03-2018 IPR033436 MucB/RseB, C-terminal CVS48_RS28285 2f431e6be23cbef0a3e21014b49725dd 348 Gene3D G3DSA:2.50.20.10 47 235 1.4E-18 T 29-03-2018 CVS48_RS28285 2f431e6be23cbef0a3e21014b49725dd 348 Pfam PF03888 MucB/RseB N-terminal domain 51 224 4.1E-60 T 29-03-2018 IPR033434 MucB/RseB, N-terminal CVS48_RS28285 2f431e6be23cbef0a3e21014b49725dd 348 PIRSF PIRSF005427 14 346 5.8E-99 T 29-03-2018 IPR005588 MucB/RseB CVS48_RS16775 e02aaabdce6f804b924fff1c97ece33e 289 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 238 1.8E-10 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CVS48_RS16775 e02aaabdce6f804b924fff1c97ece33e 289 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 2 282 1.6E-119 T 29-03-2018 IPR022522 Flagellar motor stator, MotA CVS48_RS16775 e02aaabdce6f804b924fff1c97ece33e 289 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 29-03-2018 IPR000540 Flagellar motor protein MotA, conserved site CVS48_RS16030 8c116d07eea5144d4f03f9fa76a8fa27 247 SUPERFAMILY SSF53639 7 213 2.55E-63 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS16030 8c116d07eea5144d4f03f9fa76a8fa27 247 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 195 2.0E-47 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS16030 8c116d07eea5144d4f03f9fa76a8fa27 247 SMART SM01007 12 195 2.2E-64 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS16030 8c116d07eea5144d4f03f9fa76a8fa27 247 Gene3D G3DSA:3.40.225.10 2 242 3.2E-78 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CVS48_RS12015 74a52ca92d28fe2e8349a91043185477 260 Pfam PF07103 Protein of unknown function (DUF1365) 2 245 3.2E-62 T 29-03-2018 IPR010775 Protein of unknown function DUF1365 CVS48_RS00300 a50fad61e9c8a9334509594004467e10 598 PIRSF PIRSF001294 1 598 1.0E-234 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CVS48_RS00300 a50fad61e9c8a9334509594004467e10 598 Pfam PF03814 Potassium-transporting ATPase A subunit 11 596 1.1E-239 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CVS48_RS00300 a50fad61e9c8a9334509594004467e10 598 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 598 35.393 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CVS48_RS00300 a50fad61e9c8a9334509594004467e10 598 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 235 597 8.4E-155 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CVS48_RS13200 e595abdaf7043ea0889b438b028c0d97 218 Gene3D G3DSA:3.40.30.10 5 208 3.6E-31 T 29-03-2018 CVS48_RS13200 e595abdaf7043ea0889b438b028c0d97 218 Pfam PF01323 DSBA-like thioredoxin domain 11 188 6.2E-8 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CVS48_RS13200 e595abdaf7043ea0889b438b028c0d97 218 SUPERFAMILY SSF52833 7 212 1.45E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS26425 0594e5df6f2c3b08049da37255eccfa4 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 176 5.0E-13 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CVS48_RS26425 0594e5df6f2c3b08049da37255eccfa4 226 SMART SM00702 1 177 1.0E-28 T 29-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 CVS48_RS26425 0594e5df6f2c3b08049da37255eccfa4 226 Gene3D G3DSA:2.60.120.620 2 187 4.7E-32 T 29-03-2018 CVS48_RS26425 0594e5df6f2c3b08049da37255eccfa4 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 46.455 T 29-03-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 CVS48_RS20100 0dfb8cb1e8c9608d38f952f2620ee6df 256 Pfam PF05742 Transport and Golgi organisation 2 1 238 2.7E-56 T 29-03-2018 IPR008551 Transport and Golgi organisation protein 2 CVS48_RS23885 3ff9d69e8e609a516943fb644cb4572b 534 Pfam PF00884 Sulfatase 5 383 3.4E-54 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CVS48_RS23885 3ff9d69e8e609a516943fb644cb4572b 534 Gene3D G3DSA:3.40.720.10 1 411 2.7E-80 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS23885 3ff9d69e8e609a516943fb644cb4572b 534 SUPERFAMILY SSF53649 6 109 1.67E-107 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS23885 3ff9d69e8e609a516943fb644cb4572b 534 SUPERFAMILY SSF53649 151 504 1.67E-107 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS23885 3ff9d69e8e609a516943fb644cb4572b 534 Gene3D G3DSA:3.30.1120.10 440 526 1.1E-12 T 29-03-2018 CVS48_RS01550 dd136740dc6548a328f0eb08a171c844 523 Gene3D G3DSA:3.10.105.10 285 493 1.1E-41 T 29-03-2018 CVS48_RS01550 dd136740dc6548a328f0eb08a171c844 523 SUPERFAMILY SSF53850 17 505 1.99E-118 T 29-03-2018 CVS48_RS01550 dd136740dc6548a328f0eb08a171c844 523 PIRSF PIRSF002741 8 520 6.5E-83 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CVS48_RS01550 dd136740dc6548a328f0eb08a171c844 523 Gene3D G3DSA:3.90.76.10 33 177 7.4E-34 T 29-03-2018 CVS48_RS01550 dd136740dc6548a328f0eb08a171c844 523 Gene3D G3DSA:3.40.190.10 178 284 9.9E-23 T 29-03-2018 CVS48_RS01550 dd136740dc6548a328f0eb08a171c844 523 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 65 435 4.9E-81 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CVS48_RS04980 55e5d6c7a6a993a85b8e995f4c4a61cd 268 Pfam PF15916 Domain of unknown function (DUF4743) 24 117 1.0E-5 T 29-03-2018 IPR031804 Domain of unknown function DUF4743 CVS48_RS04980 55e5d6c7a6a993a85b8e995f4c4a61cd 268 SUPERFAMILY SSF55811 100 262 9.34E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS04980 55e5d6c7a6a993a85b8e995f4c4a61cd 268 Pfam PF00293 NUDIX domain 126 203 2.8E-10 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CVS48_RS04980 55e5d6c7a6a993a85b8e995f4c4a61cd 268 Gene3D G3DSA:3.90.79.10 87 264 7.7E-23 T 29-03-2018 CVS48_RS09300 b70c952005390485ed10525868cf28ee 250 Pfam PF00005 ABC transporter 22 177 3.4E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS09300 b70c952005390485ed10525868cf28ee 250 SUPERFAMILY SSF52540 5 246 6.09E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS09300 b70c952005390485ed10525868cf28ee 250 SMART SM00382 30 224 3.7E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS09300 b70c952005390485ed10525868cf28ee 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 1.9E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CVS48_RS09300 b70c952005390485ed10525868cf28ee 250 Gene3D G3DSA:3.40.50.300 2 249 7.9E-52 T 29-03-2018 CVS48_RS04915 d63ca3a78c8e1d3fa15cec510f01d28a 227 Pfam PF05433 Glycine zipper 2TM domain 136 176 4.2E-8 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CVS48_RS25905 751d96f50273d940e3fd17824e142459 335 PIRSF PIRSF017082 6 335 1.2E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25905 751d96f50273d940e3fd17824e142459 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 332 1.1E-66 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS25905 751d96f50273d940e3fd17824e142459 335 Gene3D G3DSA:3.40.190.10 145 304 2.2E-10 T 29-03-2018 CVS48_RS25905 751d96f50273d940e3fd17824e142459 335 SUPERFAMILY SSF53850 126 298 2.31E-9 T 29-03-2018 CVS48_RS25270 9438ece1381623cb40e967e1f1e71893 163 SUPERFAMILY SSF88946 4 94 3.92E-11 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25270 9438ece1381623cb40e967e1f1e71893 163 Gene3D G3DSA:1.10.10.10 83 159 1.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25270 9438ece1381623cb40e967e1f1e71893 163 Pfam PF04542 Sigma-70 region 2 9 73 3.4E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25270 9438ece1381623cb40e967e1f1e71893 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 157 6.5E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25270 9438ece1381623cb40e967e1f1e71893 163 Gene3D G3DSA:1.10.1740.10 2 77 2.1E-11 T 29-03-2018 CVS48_RS25270 9438ece1381623cb40e967e1f1e71893 163 Pfam PF08281 Sigma-70, region 4 110 157 6.8E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS25270 9438ece1381623cb40e967e1f1e71893 163 SUPERFAMILY SSF88659 83 158 7.63E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CVS48_RS09165 a1fcb70245e60475171a94ed4e3bebd1 216 Pfam PF00484 Carbonic anhydrase 38 195 4.7E-48 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS09165 a1fcb70245e60475171a94ed4e3bebd1 216 SMART SM00947 30 200 2.9E-63 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS09165 a1fcb70245e60475171a94ed4e3bebd1 216 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 89 109 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS09165 a1fcb70245e60475171a94ed4e3bebd1 216 SUPERFAMILY SSF53056 3 209 1.3E-57 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS09165 a1fcb70245e60475171a94ed4e3bebd1 216 Gene3D G3DSA:3.40.1050.10 3 210 9.8E-57 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CVS48_RS11600 47670ace991bd99992b206855afb7c6c 333 PIRSF PIRSF017082 7 332 1.3E-76 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11600 47670ace991bd99992b206855afb7c6c 333 SUPERFAMILY SSF53850 122 296 7.17E-11 T 29-03-2018 CVS48_RS11600 47670ace991bd99992b206855afb7c6c 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 329 2.8E-80 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS11600 47670ace991bd99992b206855afb7c6c 333 Gene3D G3DSA:3.40.190.10 132 241 3.3E-11 T 29-03-2018 CVS48_RS15995 a82b5c51cc107980033a5bbbcefa4b28 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 257 2.5E-76 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CVS48_RS15995 a82b5c51cc107980033a5bbbcefa4b28 260 Gene3D G3DSA:3.60.10.10 1 259 3.1E-52 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS15995 a82b5c51cc107980033a5bbbcefa4b28 260 SUPERFAMILY SSF56219 1 258 5.76E-80 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS15995 a82b5c51cc107980033a5bbbcefa4b28 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 257 4.8E-78 T 29-03-2018 CVS48_RS15995 a82b5c51cc107980033a5bbbcefa4b28 260 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 214 225 - T 29-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 CVS48_RS15995 a82b5c51cc107980033a5bbbcefa4b28 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 5.2E-19 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS19985 9e548ece69cff5f8500b6ad7ff089a35 129 Pfam PF10861 Protein of Unknown function (DUF2784) 4 111 6.5E-36 T 29-03-2018 IPR021218 Protein of unknown function DUF2784 CVS48_RS16215 aaf3e2a79ceb372f994debf244ba4b11 649 Gene3D G3DSA:3.40.190.10 9 605 2.2E-4 T 29-03-2018 CVS48_RS16215 aaf3e2a79ceb372f994debf244ba4b11 649 Pfam PF05787 Bacterial protein of unknown function (DUF839) 209 593 2.6E-22 T 29-03-2018 IPR008557 Protein of unknown function DUF839 CVS48_RS09350 83c183e1827c45787518c8788da496ac 302 Pfam PF02687 FtsX-like permease family 206 299 6.8E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CVS48_RS09350 83c183e1827c45787518c8788da496ac 302 PIRSF PIRSF003097 2 302 3.6E-53 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CVS48_RS19645 f48a8c694280cbcae9ef362e51a542eb 449 SUPERFAMILY SSF75304 5 447 3.27E-111 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS19645 f48a8c694280cbcae9ef362e51a542eb 449 Pfam PF01425 Amidase 22 436 8.0E-80 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS19645 f48a8c694280cbcae9ef362e51a542eb 449 Gene3D G3DSA:3.90.1300.10 3 447 7.1E-115 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS19645 f48a8c694280cbcae9ef362e51a542eb 449 ProSitePatterns PS00571 Amidases signature. 153 184 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CVS48_RS07875 0de9cad4b468682b5089c829d24d50ba 302 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 233 242 - T 29-03-2018 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|Reactome: R-HSA-77111 CVS48_RS07875 0de9cad4b468682b5089c829d24d50ba 302 Gene3D G3DSA:3.20.20.70 2 299 1.2E-110 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS07875 0de9cad4b468682b5089c829d24d50ba 302 SUPERFAMILY SSF51569 2 288 1.76E-74 T 29-03-2018 CVS48_RS07875 0de9cad4b468682b5089c829d24d50ba 302 Pfam PF00682 HMGL-like 6 278 1.4E-54 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CVS48_RS18885 6e444085f7ec473642b2bcaa76a0631b 159 Pfam PF07080 Protein of unknown function (DUF1348) 12 141 2.9E-64 T 29-03-2018 IPR009783 Protein of unknown function DUF1348 CVS48_RS18885 6e444085f7ec473642b2bcaa76a0631b 159 Gene3D G3DSA:3.10.450.50 15 159 5.8E-70 T 29-03-2018 CVS48_RS18885 6e444085f7ec473642b2bcaa76a0631b 159 SUPERFAMILY SSF54427 7 159 1.29E-78 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS24605 6e29c8640e189401c9126b147f560883 230 SMART SM00507 175 225 0.002 T 29-03-2018 IPR003615 HNH nuclease CVS48_RS24605 6e29c8640e189401c9126b147f560883 230 Pfam PF01844 HNH endonuclease 178 229 3.7E-11 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CVS48_RS24605 6e29c8640e189401c9126b147f560883 230 Gene3D G3DSA:3.40.1800.10 161 229 9.8E-12 T 29-03-2018 CVS48_RS23085 2811f823a7db27856ed6d979388330cd 283 Pfam PF01925 Sulfite exporter TauE/SafE 7 280 1.1E-35 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CVS48_RS18045 3740e74bbc9165e1121c3b3314112c51 389 Pfam PF07786 Protein of unknown function (DUF1624) 14 231 7.0E-16 T 29-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 CVS48_RS25430 54e59a21edf99285a7c02f1615d118fc 168 Pfam PF09722 Protein of unknown function (DUF2384) 116 165 2.5E-8 T 29-03-2018 IPR024467 Domain of unknown function DUF2384 CVS48_RS05070 a01ef952b416d0a0341aeb7546a02971 209 Gene3D G3DSA:1.10.10.640 172 209 2.9E-7 T 29-03-2018 CVS48_RS05070 a01ef952b416d0a0341aeb7546a02971 209 Pfam PF05494 MlaC protein 43 206 7.0E-54 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC CVS48_RS05070 a01ef952b416d0a0341aeb7546a02971 209 Gene3D G3DSA:3.10.450.50 82 171 1.7E-25 T 29-03-2018 CVS48_RS05070 a01ef952b416d0a0341aeb7546a02971 209 Gene3D G3DSA:3.10.450.50 35 81 0.064 T 29-03-2018 CVS48_RS05070 a01ef952b416d0a0341aeb7546a02971 209 PIRSF PIRSF004649 7 209 8.3E-48 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC CVS48_RS16545 7a835c5ff4bfbf7011b9a704ce28b8af 687 Pfam PF01968 Hydantoinase/oxoprolinase 207 497 4.4E-88 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CVS48_RS16545 7a835c5ff4bfbf7011b9a704ce28b8af 687 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 14 186 4.6E-49 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CVS48_RS16545 7a835c5ff4bfbf7011b9a704ce28b8af 687 Gene3D G3DSA:3.30.420.150 268 341 0.0085 T 29-03-2018 CVS48_RS16545 7a835c5ff4bfbf7011b9a704ce28b8af 687 Gene3D G3DSA:3.30.420.40 5 108 3.5E-7 T 29-03-2018 CVS48_RS04930 98df512a68c487cd1870f755abe33633 297 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 14 291 3.8E-91 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CVS48_RS04930 98df512a68c487cd1870f755abe33633 297 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 11 292 18.959 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CVS48_RS04930 98df512a68c487cd1870f755abe33633 297 Pfam PF01040 UbiA prenyltransferase family 27 275 9.8E-56 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CVS48_RS15430 9eecea517e60a91b70afa463f924a21f 414 Gene3D G3DSA:3.50.50.60 2 173 1.7E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS15430 9eecea517e60a91b70afa463f924a21f 414 Pfam PF01494 FAD binding domain 5 222 3.9E-16 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS15430 9eecea517e60a91b70afa463f924a21f 414 Gene3D G3DSA:3.30.9.10 174 325 4.5E-17 T 29-03-2018 CVS48_RS15430 9eecea517e60a91b70afa463f924a21f 414 SUPERFAMILY SSF51905 3 173 3.6E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS15430 9eecea517e60a91b70afa463f924a21f 414 SUPERFAMILY SSF51905 281 360 3.6E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS18250 683f44379e946a4809529b57c2c97826 159 Gene3D G3DSA:1.20.1630.10 1 158 1.4E-4 T 29-03-2018 CVS48_RS18250 683f44379e946a4809529b57c2c97826 159 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 25 150 2.5E-23 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS14555 1ef75f3dcc1e28e25bfb63511bd77887 418 Pfam PF01266 FAD dependent oxidoreductase 2 403 6.5E-66 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CVS48_RS14555 1ef75f3dcc1e28e25bfb63511bd77887 418 SUPERFAMILY SSF51905 1 54 4.92E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14555 1ef75f3dcc1e28e25bfb63511bd77887 418 SUPERFAMILY SSF51905 107 275 4.92E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14555 1ef75f3dcc1e28e25bfb63511bd77887 418 SUPERFAMILY SSF51905 365 413 4.92E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS14555 1ef75f3dcc1e28e25bfb63511bd77887 418 SUPERFAMILY SSF54373 275 365 8.76E-16 T 29-03-2018 CVS48_RS14555 1ef75f3dcc1e28e25bfb63511bd77887 418 Gene3D G3DSA:3.50.50.60 1 416 7.7E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS23420 bc0faab6579fbb1eb6cc73dc3d1ab1c0 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 236 2.0E-50 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS23420 bc0faab6579fbb1eb6cc73dc3d1ab1c0 267 SUPERFAMILY SSF52096 1 250 3.08E-67 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS23420 bc0faab6579fbb1eb6cc73dc3d1ab1c0 267 Gene3D G3DSA:3.90.226.10 1 266 2.2E-61 T 29-03-2018 CVS48_RS06840 b7853f70f2310232c06d21fb89937fce 102 Pfam PF13663 Domain of unknown function (DUF4148) 1 60 1.4E-13 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS06840 b7853f70f2310232c06d21fb89937fce 102 Pfam PF13663 Domain of unknown function (DUF4148) 62 98 1.1E-10 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS06840 b7853f70f2310232c06d21fb89937fce 102 Gene3D G3DSA:1.10.287.180 19 63 0.023 T 29-03-2018 CVS48_RS04830 ec0ee27e94c6065571aa5f1025d74656 440 SUPERFAMILY SSF48452 159 262 1.24E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS04830 ec0ee27e94c6065571aa5f1025d74656 440 Gene3D G3DSA:1.25.40.10 87 437 2.6E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS12250 a8d354ff62ce81eda62c184561467531 351 SUPERFAMILY SSF51004 16 346 2.88E-50 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CVS48_RS12250 a8d354ff62ce81eda62c184561467531 351 Gene3D G3DSA:2.130.10.10 265 347 1.9E-11 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS12250 a8d354ff62ce81eda62c184561467531 351 Gene3D G3DSA:2.130.10.10 1 264 2.1E-36 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CVS48_RS12250 a8d354ff62ce81eda62c184561467531 351 Pfam PF10282 Lactonase, 7-bladed beta-propeller 2 346 1.1E-102 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CVS48_RS21505 e269fdab7b546c96e8fba516b5c0e3cd 365 Pfam PF07042 TrfA protein 93 334 1.2E-5 T 29-03-2018 IPR010751 Plasmid replication initiator protein TrfA CVS48_RS15890 d66c9713daf56df01acbefd890a30295 224 SUPERFAMILY SSF52317 1 182 1.48E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS15890 d66c9713daf56df01acbefd890a30295 224 Gene3D G3DSA:3.40.50.880 1 224 5.6E-60 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CVS48_RS15890 d66c9713daf56df01acbefd890a30295 224 Pfam PF01965 DJ-1/PfpI family 2 162 2.9E-30 T 29-03-2018 IPR002818 DJ-1/PfpI CVS48_RS05025 e025988f28f7f2cff207da12a380460b 212 SUPERFAMILY SSF56925 32 212 8.89E-30 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CVS48_RS05025 e025988f28f7f2cff207da12a380460b 212 Pfam PF03922 OmpW family 30 212 1.5E-51 T 29-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 CVS48_RS05025 e025988f28f7f2cff207da12a380460b 212 Gene3D G3DSA:2.40.160.20 29 212 1.1E-36 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CVS48_RS05335 21eb1c0d41ed5ef8d06d587ac002db06 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 4.7E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05335 21eb1c0d41ed5ef8d06d587ac002db06 323 Gene3D G3DSA:1.10.3720.10 3 308 3.9E-40 T 29-03-2018 CVS48_RS05335 21eb1c0d41ed5ef8d06d587ac002db06 323 SUPERFAMILY SSF161098 92 305 3.08E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20375 86e4fd064020c863ddd2519479cb2e7c 299 SUPERFAMILY SSF50630 182 282 1.58E-8 T 29-03-2018 IPR021109 Aspartic peptidase domain CVS48_RS20375 86e4fd064020c863ddd2519479cb2e7c 299 Gene3D G3DSA:2.40.70.10 32 169 5.5E-4 T 29-03-2018 IPR021109 Aspartic peptidase domain CVS48_RS20375 86e4fd064020c863ddd2519479cb2e7c 299 Gene3D G3DSA:2.40.70.10 181 298 3.0E-12 T 29-03-2018 IPR021109 Aspartic peptidase domain CVS48_RS20375 86e4fd064020c863ddd2519479cb2e7c 299 Pfam PF13650 Aspartyl protease 191 272 1.8E-5 T 29-03-2018 CVS48_RS00660 f832787f70d6b61643d68d471046babe 963 SUPERFAMILY SSF52540 487 614 4.68E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00660 f832787f70d6b61643d68d471046babe 963 SUPERFAMILY SSF52540 650 884 4.68E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS00660 f832787f70d6b61643d68d471046babe 963 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 65 343 1.1E-71 T 29-03-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase CVS48_RS00660 f832787f70d6b61643d68d471046babe 963 Gene3D G3DSA:3.40.50.300 533 901 4.7E-16 T 29-03-2018 CVS48_RS00660 f832787f70d6b61643d68d471046babe 963 TIGRFAM TIGR03744 traC_PFL_4706: conjugative transfer ATPase, PFL_4706 family 54 954 0.0 T 29-03-2018 IPR022303 Conjugative transfer ATPase CVS48_RS08965 ebdd6dfc127d400fdee5c4fab1012da1 396 SUPERFAMILY SSF89796 4 396 8.11E-131 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS08965 ebdd6dfc127d400fdee5c4fab1012da1 396 Gene3D G3DSA:3.40.50.10540 1 396 1.3E-139 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS08965 ebdd6dfc127d400fdee5c4fab1012da1 396 Pfam PF02515 CoA-transferase family III 6 373 1.3E-126 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS07580 38392705f984e3e3e89089afb3bb6419 208 Pfam PF01810 LysE type translocator 22 206 1.4E-33 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS00400 75a0bfc51c4dab0854a32d32aacc4b0e 129 Pfam PF13663 Domain of unknown function (DUF4148) 95 125 1.4E-8 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS00400 75a0bfc51c4dab0854a32d32aacc4b0e 129 Pfam PF13663 Domain of unknown function (DUF4148) 1 54 5.5E-12 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS12710 16a1f5dd40a7426ad4f37aec383d6a83 322 PIRSF PIRSF017082 3 322 3.3E-68 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS12710 16a1f5dd40a7426ad4f37aec383d6a83 322 Gene3D G3DSA:3.40.190.10 122 295 7.6E-5 T 29-03-2018 CVS48_RS12710 16a1f5dd40a7426ad4f37aec383d6a83 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 6.2E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS12710 16a1f5dd40a7426ad4f37aec383d6a83 322 SUPERFAMILY SSF53850 111 281 5.97E-10 T 29-03-2018 CVS48_RS25455 cfd01ac2e4a5556d0a1a3ab26d7e43fb 237 Gene3D G3DSA:3.30.1150.10 140 229 9.4E-9 T 29-03-2018 CVS48_RS25455 cfd01ac2e4a5556d0a1a3ab26d7e43fb 237 Pfam PF13103 TonB C terminal 150 212 1.4E-5 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CVS48_RS25455 cfd01ac2e4a5556d0a1a3ab26d7e43fb 237 SUPERFAMILY SSF74653 137 221 4.12E-6 T 29-03-2018 CVS48_RS25455 cfd01ac2e4a5556d0a1a3ab26d7e43fb 237 SUPERFAMILY SSF74653 59 72 4.12E-6 T 29-03-2018 CVS48_RS18950 1ea4219b903b2d34e2bc8549f1a3826d 388 Gene3D G3DSA:3.90.1580.10 48 386 1.8E-89 T 29-03-2018 CVS48_RS18950 1ea4219b903b2d34e2bc8549f1a3826d 388 SUPERFAMILY SSF56436 54 371 2.07E-81 T 29-03-2018 IPR016187 C-type lectin fold CVS48_RS18950 1ea4219b903b2d34e2bc8549f1a3826d 388 Pfam PF03781 Sulfatase-modifying factor enzyme 1 55 369 2.2E-78 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CVS48_RS23460 2c3c10faba7bca7f396b2911b89302ca 254 Pfam PF01925 Sulfite exporter TauE/SafE 10 241 4.3E-18 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CVS48_RS16165 6b693dc360f89ee5db0004e58167f585 317 Gene3D G3DSA:3.30.1300.30 30 152 1.6E-22 T 29-03-2018 CVS48_RS16165 6b693dc360f89ee5db0004e58167f585 317 SUPERFAMILY SSF54523 277 302 3.4E-5 T 29-03-2018 CVS48_RS16165 6b693dc360f89ee5db0004e58167f585 317 SUPERFAMILY SSF54523 40 110 3.4E-5 T 29-03-2018 CVS48_RS16165 6b693dc360f89ee5db0004e58167f585 317 SUPERFAMILY SSF47781 214 261 2.45E-5 T 29-03-2018 IPR010994 RuvA domain 2-like CVS48_RS16165 6b693dc360f89ee5db0004e58167f585 317 PIRSF PIRSF002786 4 317 1.6E-66 T 29-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 CVS48_RS16165 6b693dc360f89ee5db0004e58167f585 317 Pfam PF03934 Type II secretion system (T2SS), protein K 34 303 4.2E-59 T 29-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 CVS48_RS16165 6b693dc360f89ee5db0004e58167f585 317 Gene3D G3DSA:1.10.40.60 217 277 1.6E-9 T 29-03-2018 CVS48_RS17285 7cff8919898d2f2432c1dc4a48ecaece 332 SUPERFAMILY SSF103025 18 247 2.83E-48 T 29-03-2018 CVS48_RS17285 7cff8919898d2f2432c1dc4a48ecaece 332 Gene3D G3DSA:3.30.70.1400 24 244 1.4E-23 T 29-03-2018 CVS48_RS17285 7cff8919898d2f2432c1dc4a48ecaece 332 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 192 254 1.6E-26 T 29-03-2018 IPR017703 YgfZ/GcvT conserved site CVS48_RS13520 67dc1a266785b6d934b491368e78bcbe 158 Pfam PF16155 Domain of unknown function (DUF4863) 11 153 9.3E-57 T 29-03-2018 IPR032345 Protein of unknown function DUF4863 CVS48_RS00825 8b96403dffd72dcf81b233a7cdb62b2a 275 Pfam PF06067 Domain of unknown function (DUF932) 37 264 2.0E-61 T 29-03-2018 IPR026325 Protein of unknown function DUF932 CVS48_RS01465 cb34656e0c30b8c334a3e32561e12b60 350 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 20 334 1.1E-58 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CVS48_RS28485 cb76ba19264ff76b4b894abc2609c164 327 Gene3D G3DSA:1.10.3470.10 5 309 5.3E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS28485 cb76ba19264ff76b4b894abc2609c164 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 302 2.1E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS17570 c7cb5f87e47cd9fc203543658a32513d 385 SUPERFAMILY SSF51412 15 312 1.14E-28 T 29-03-2018 CVS48_RS17570 c7cb5f87e47cd9fc203543658a32513d 385 Gene3D G3DSA:3.20.20.70 1 379 2.7E-27 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS17570 c7cb5f87e47cd9fc203543658a32513d 385 Pfam PF03060 Nitronate monooxygenase 16 304 4.0E-28 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CVS48_RS24155 c8c1f22ef169fbaa896657095dc88134 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 268 5.4E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS24155 c8c1f22ef169fbaa896657095dc88134 275 SUPERFAMILY SSF161098 76 260 2.62E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS24155 c8c1f22ef169fbaa896657095dc88134 275 Gene3D G3DSA:1.10.3720.10 29 274 1.2E-20 T 29-03-2018 CVS48_RS19455 2f05f918468addcfca74b3d85864ddc4 301 SUPERFAMILY SSF51182 13 286 2.82E-82 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS19455 2f05f918468addcfca74b3d85864ddc4 301 Pfam PF05726 Pirin C-terminal cupin domain 184 283 2.2E-26 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 CVS48_RS19455 2f05f918468addcfca74b3d85864ddc4 301 Pfam PF02678 Pirin 26 131 1.0E-34 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CVS48_RS19455 2f05f918468addcfca74b3d85864ddc4 301 PIRSF PIRSF006232 9 291 5.0E-86 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CVS48_RS19455 2f05f918468addcfca74b3d85864ddc4 301 Gene3D G3DSA:2.60.120.10 9 255 1.8E-64 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS04515 c6ca2eef889f19a3159073765e45726d 467 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 395 415 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CVS48_RS04515 c6ca2eef889f19a3159073765e45726d 467 Pfam PF00474 Sodium:solute symporter family 32 413 1.6E-37 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS03470 d47cba7fb580ce04d2ae6059b607f74a 321 Gene3D G3DSA:1.10.3470.10 20 304 3.6E-39 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS03470 d47cba7fb580ce04d2ae6059b607f74a 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 293 1.6E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 Hamap MF_00416 Flagellar P-ring protein [flgI]. 14 378 38.301 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 Pfam PF02119 Flagellar P-ring protein 34 377 1.4E-137 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 PRINTS PR01010 Flagellar P-ring protein signature 134 152 2.9E-84 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 PRINTS PR01010 Flagellar P-ring protein signature 200 218 2.9E-84 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 PRINTS PR01010 Flagellar P-ring protein signature 34 49 2.9E-84 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 PRINTS PR01010 Flagellar P-ring protein signature 95 114 2.9E-84 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 PRINTS PR01010 Flagellar P-ring protein signature 117 134 2.9E-84 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 PRINTS PR01010 Flagellar P-ring protein signature 49 64 2.9E-84 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 PRINTS PR01010 Flagellar P-ring protein signature 264 276 2.9E-84 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 PRINTS PR01010 Flagellar P-ring protein signature 174 192 2.9E-84 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS16895 45db0eee2e47472a78f0a6f426c0e7de 378 PRINTS PR01010 Flagellar P-ring protein signature 69 84 2.9E-84 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CVS48_RS05960 0342697acf1c47a2a69a9050ef5baeb2 298 Gene3D G3DSA:2.60.120.620 1 262 1.6E-36 T 29-03-2018 CVS48_RS05960 0342697acf1c47a2a69a9050ef5baeb2 298 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 15 223 7.3E-27 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CVS48_RS05960 0342697acf1c47a2a69a9050ef5baeb2 298 SUPERFAMILY SSF51197 4 234 1.01E-48 T 29-03-2018 CVS48_RS08605 4ec4b4e48785649574140ca75c04a3fb 690 Gene3D G3DSA:3.40.190.10 27 618 9.6E-6 T 29-03-2018 CVS48_RS08605 4ec4b4e48785649574140ca75c04a3fb 690 Pfam PF05787 Bacterial protein of unknown function (DUF839) 79 652 1.9E-142 T 29-03-2018 IPR008557 Protein of unknown function DUF839 CVS48_RS02630 b9e3af4549f2ce27c411e180617718e0 209 Pfam PF02525 Flavodoxin-like fold 1 196 7.8E-46 T 29-03-2018 IPR003680 Flavodoxin-like fold CVS48_RS02630 b9e3af4549f2ce27c411e180617718e0 209 SUPERFAMILY SSF52218 1 198 4.04E-55 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS02630 b9e3af4549f2ce27c411e180617718e0 209 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 199 30.953 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CVS48_RS02630 b9e3af4549f2ce27c411e180617718e0 209 Gene3D G3DSA:3.40.50.360 1 206 2.3E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain CVS48_RS23540 093f90efc0f0f5884888a837cc601959 400 Pfam PF11062 Protein of unknown function (DUF2863) 5 399 3.9E-170 T 29-03-2018 IPR021292 Protein of unknown function DUF2863 CVS48_RS17265 ecdec22c1f843441b69ace5c9399d6a5 391 Pfam PF16113 Enoyl-CoA hydratase/isomerase 19 371 2.5E-114 T 29-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CVS48_RS17265 ecdec22c1f843441b69ace5c9399d6a5 391 Gene3D G3DSA:3.90.226.10 4 365 2.1E-78 T 29-03-2018 CVS48_RS17265 ecdec22c1f843441b69ace5c9399d6a5 391 SUPERFAMILY SSF52096 18 198 3.09E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS17265 ecdec22c1f843441b69ace5c9399d6a5 391 SUPERFAMILY SSF52096 281 357 3.09E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS13870 606aebfa27dd0558fd9621e9ea30face 268 Pfam PF13444 Acetyltransferase (GNAT) domain 42 143 1.3E-31 T 29-03-2018 CVS48_RS13870 606aebfa27dd0558fd9621e9ea30face 268 Gene3D G3DSA:3.40.630.30 24 190 4.8E-36 T 29-03-2018 CVS48_RS13870 606aebfa27dd0558fd9621e9ea30face 268 SUPERFAMILY SSF55729 25 232 1.87E-43 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS13590 2a6042175abb201161f674fc15bcb267 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 336 1.1E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13590 2a6042175abb201161f674fc15bcb267 338 SUPERFAMILY SSF161098 95 163 2.45E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13590 2a6042175abb201161f674fc15bcb267 338 SUPERFAMILY SSF161098 200 324 2.45E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13590 2a6042175abb201161f674fc15bcb267 338 Gene3D G3DSA:1.10.3720.10 3 325 4.9E-38 T 29-03-2018 CVS48_RS09335 df8babf9a265c214d66d706341008d60 186 SUPERFAMILY SSF56784 2 177 4.27E-38 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS09335 df8babf9a265c214d66d706341008d60 186 Gene3D G3DSA:3.40.50.1000 58 179 6.9E-30 T 29-03-2018 IPR023214 HAD-like domain CVS48_RS09335 df8babf9a265c214d66d706341008d60 186 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 1 176 7.4E-24 T 29-03-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 CVS48_RS09335 df8babf9a265c214d66d706341008d60 186 Gene3D G3DSA:1.10.40.40 14 57 5.0E-16 T 29-03-2018 CVS48_RS25925 d5af69d92cead09b21689c0e785ae16f 333 Gene3D G3DSA:3.40.190.10 166 324 3.2E-31 T 29-03-2018 CVS48_RS25925 d5af69d92cead09b21689c0e785ae16f 333 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 312 4.2E-62 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CVS48_RS25925 d5af69d92cead09b21689c0e785ae16f 333 Gene3D G3DSA:3.40.190.10 27 165 5.5E-19 T 29-03-2018 CVS48_RS25925 d5af69d92cead09b21689c0e785ae16f 333 SUPERFAMILY SSF53850 31 328 2.5E-81 T 29-03-2018 CVS48_RS17685 69b044170584cb956e22b63943d8a27d 439 Pfam PF05940 NnrS protein 24 418 8.3E-86 T 29-03-2018 IPR010266 NnrS CVS48_RS00455 1c1fb5c2c585b28d01c67691c4b5cda4 139 Pfam PF01475 Ferric uptake regulator family 10 129 7.0E-46 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CVS48_RS00455 1c1fb5c2c585b28d01c67691c4b5cda4 139 SUPERFAMILY SSF46785 5 133 4.54E-41 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS00455 1c1fb5c2c585b28d01c67691c4b5cda4 139 Gene3D G3DSA:1.10.10.10 3 89 4.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS05985 64bc6b6d95a974c6593c78eea45b7d99 229 Gene3D G3DSA:1.10.3720.10 2 227 8.3E-37 T 29-03-2018 CVS48_RS05985 64bc6b6d95a974c6593c78eea45b7d99 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 226 1.6E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS05985 64bc6b6d95a974c6593c78eea45b7d99 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 120 3.1E-22 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS05985 64bc6b6d95a974c6593c78eea45b7d99 229 SUPERFAMILY SSF161098 17 211 1.83E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18420 aad49608f9a73659341f14bb7b0c0ca4 389 Pfam PF11379 Protein of unknown function (DUF3182) 17 370 3.7E-134 T 29-03-2018 IPR021519 Protein of unknown function DUF3182 CVS48_RS18420 aad49608f9a73659341f14bb7b0c0ca4 389 SUPERFAMILY SSF56059 128 242 2.55E-8 T 29-03-2018 CVS48_RS18420 aad49608f9a73659341f14bb7b0c0ca4 389 Gene3D G3DSA:3.30.470.20 115 295 4.4E-8 T 29-03-2018 CVS48_RS18330 46c74a0582e0dc0b50b9a3213cfbc419 574 Pfam PF02538 Hydantoinase B/oxoprolinase 20 543 1.8E-138 T 29-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 CVS48_RS25985 0cf8e82af0edfbdf17764688ed7d0ec6 172 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CVS48_RS25985 0cf8e82af0edfbdf17764688ed7d0ec6 172 Gene3D G3DSA:1.10.10.10 13 166 4.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS25985 0cf8e82af0edfbdf17764688ed7d0ec6 172 SMART SM00347 45 148 1.1E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25985 0cf8e82af0edfbdf17764688ed7d0ec6 172 Pfam PF01047 MarR family 54 112 1.6E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25985 0cf8e82af0edfbdf17764688ed7d0ec6 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 1.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25985 0cf8e82af0edfbdf17764688ed7d0ec6 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 1.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25985 0cf8e82af0edfbdf17764688ed7d0ec6 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 1.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25985 0cf8e82af0edfbdf17764688ed7d0ec6 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 1.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS25985 0cf8e82af0edfbdf17764688ed7d0ec6 172 SUPERFAMILY SSF46785 12 159 2.15E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS27610 c3f4857c0bb85b411c6e85afdf2cd454 160 Pfam PF08909 Domain of unknown function (DUF1854) 30 159 1.3E-52 T 29-03-2018 IPR015005 Domain of unknown function DUF1854 CVS48_RS18320 9a4b1b12fca57ef0104d0affc16a0f4f 327 Gene3D G3DSA:1.10.3720.10 1 314 9.9E-43 T 29-03-2018 CVS48_RS18320 9a4b1b12fca57ef0104d0affc16a0f4f 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 325 4.4E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18320 9a4b1b12fca57ef0104d0affc16a0f4f 327 SUPERFAMILY SSF161098 96 308 4.58E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS03895 17898ff3ec4f10cdace8294be47f4583 294 Gene3D G3DSA:3.40.50.1820 24 251 4.3E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03895 17898ff3ec4f10cdace8294be47f4583 294 SUPERFAMILY SSF53474 17 279 1.79E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS03895 17898ff3ec4f10cdace8294be47f4583 294 Pfam PF07859 alpha/beta hydrolase fold 79 165 2.6E-14 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CVS48_RS00175 a6c2c7719b6ab9dad5ece1fdc5b50e23 165 Gene3D G3DSA:2.30.130.30 1 162 1.9E-23 T 29-03-2018 CVS48_RS01580 8b437dce0c59f4e94f604160934c05d6 163 Pfam PF00866 Ring hydroxylating beta subunit 15 151 1.1E-25 T 29-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CVS48_RS01580 8b437dce0c59f4e94f604160934c05d6 163 Gene3D G3DSA:3.10.450.50 2 163 1.7E-27 T 29-03-2018 CVS48_RS01580 8b437dce0c59f4e94f604160934c05d6 163 SUPERFAMILY SSF54427 6 163 3.73E-43 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS23300 8ac20885bd15810cb41740d5196adca2 228 SUPERFAMILY SSF52540 18 219 3.9E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS23300 8ac20885bd15810cb41740d5196adca2 228 SMART SM00382 27 218 1.3E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS23300 8ac20885bd15810cb41740d5196adca2 228 Pfam PF00005 ABC transporter 27 168 2.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS23300 8ac20885bd15810cb41740d5196adca2 228 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS23300 8ac20885bd15810cb41740d5196adca2 228 Gene3D G3DSA:3.40.50.300 14 224 1.4E-53 T 29-03-2018 CVS48_RS23065 a01f83312928aeac0a3a067a777de32f 170 Pfam PF09351 Domain of unknown function (DUF1993) 6 165 3.0E-62 T 29-03-2018 IPR018531 Domain of unknown function DUF1993 CVS48_RS23065 a01f83312928aeac0a3a067a777de32f 170 SUPERFAMILY SSF109854 4 168 7.94E-61 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CVS48_RS23065 a01f83312928aeac0a3a067a777de32f 170 Gene3D G3DSA:1.20.120.450 2 169 4.3E-67 T 29-03-2018 CVS48_RS01785 ccbd06ee0710c1cdce12cd1b3e4975a5 313 Pfam PF03547 Membrane transport protein 167 309 4.4E-13 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CVS48_RS08715 c7aa1f3819944f59fe5022efedaba47e 261 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 24 233 7.3E-31 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CVS48_RS08715 c7aa1f3819944f59fe5022efedaba47e 261 Gene3D G3DSA:3.20.20.60 8 258 4.5E-37 T 29-03-2018 CVS48_RS08715 c7aa1f3819944f59fe5022efedaba47e 261 SUPERFAMILY SSF51621 5 245 2.09E-65 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CVS48_RS26730 973caff619fde98f6a426567737ee863 231 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 27 230 3.6E-52 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS26730 973caff619fde98f6a426567737ee863 231 Gene3D G3DSA:3.90.850.10 6 231 2.2E-75 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS26730 973caff619fde98f6a426567737ee863 231 SUPERFAMILY SSF56529 20 231 6.28E-71 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CVS48_RS05875 ce3a7cac3d7c306150dd26105e2d4d2f 343 SUPERFAMILY SSF53850 24 339 5.24E-59 T 29-03-2018 CVS48_RS05875 ce3a7cac3d7c306150dd26105e2d4d2f 343 Gene3D G3DSA:3.40.190.10 140 299 1.6E-36 T 29-03-2018 CVS48_RS05875 ce3a7cac3d7c306150dd26105e2d4d2f 343 Gene3D G3DSA:3.40.190.10 26 139 2.3E-18 T 29-03-2018 CVS48_RS05875 ce3a7cac3d7c306150dd26105e2d4d2f 343 Pfam PF13416 Bacterial extracellular solute-binding protein 47 303 2.3E-35 T 29-03-2018 CVS48_RS23620 577c64f4edc0ab6abd2acaf098dd6e64 153 Pfam PF07811 TadE-like protein 1 39 5.5E-11 T 29-03-2018 IPR012495 TadE-like CVS48_RS20015 b3884a8d29d3c5dd60c098fe800d2af7 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 259 3.6E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS20015 b3884a8d29d3c5dd60c098fe800d2af7 270 Gene3D G3DSA:1.10.3720.10 6 263 3.1E-41 T 29-03-2018 CVS48_RS20015 b3884a8d29d3c5dd60c098fe800d2af7 270 SUPERFAMILY SSF161098 6 269 1.27E-63 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS01690 fbb27a31bf7307f0539fd84fce004d5c 103 SUPERFAMILY SSF50022 3 102 1.57E-32 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS01690 fbb27a31bf7307f0539fd84fce004d5c 103 Pfam PF00355 Rieske [2Fe-2S] domain 4 91 5.7E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS01690 fbb27a31bf7307f0539fd84fce004d5c 103 Gene3D G3DSA:2.102.10.10 1 103 2.6E-27 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CVS48_RS11110 7f1647b766ffedfc35483722462360bf 350 Gene3D G3DSA:3.30.1370.60 84 309 3.2E-75 T 29-03-2018 CVS48_RS11110 7f1647b766ffedfc35483722462360bf 350 Pfam PF02615 Malate/L-lactate dehydrogenase 10 335 2.3E-104 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CVS48_RS11110 7f1647b766ffedfc35483722462360bf 350 SUPERFAMILY SSF89733 7 343 2.88E-98 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CVS48_RS11110 7f1647b766ffedfc35483722462360bf 350 Gene3D G3DSA:1.10.1530.10 6 83 1.1E-19 T 29-03-2018 CVS48_RS21185 4c4e2c9658efaddcb401dc49c13d6360 122 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 6 117 3.8E-23 T 29-03-2018 IPR009387 Toxin HigB-2 CVS48_RS20700 35138ee00493fe38b01fd8738fd52db3 496 Gene3D G3DSA:3.90.1300.10 11 495 2.1E-121 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS20700 35138ee00493fe38b01fd8738fd52db3 496 SUPERFAMILY SSF75304 14 489 3.14E-124 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS20700 35138ee00493fe38b01fd8738fd52db3 496 Pfam PF01425 Amidase 36 468 3.5E-89 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CVS48_RS20700 35138ee00493fe38b01fd8738fd52db3 496 ProSitePatterns PS00571 Amidases signature. 165 196 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CVS48_RS24140 61446eaac279e1f639362bfa77a3b373 319 Gene3D G3DSA:3.40.190.10 123 231 1.5E-15 T 29-03-2018 CVS48_RS24140 61446eaac279e1f639362bfa77a3b373 319 SUPERFAMILY SSF53850 117 272 8.69E-14 T 29-03-2018 CVS48_RS24140 61446eaac279e1f639362bfa77a3b373 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 314 2.5E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS24140 61446eaac279e1f639362bfa77a3b373 319 PIRSF PIRSF017082 1 316 1.8E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS04675 b44e3af283876e4cd5323ffc103c3513 334 Gene3D G3DSA:3.50.30.50 45 334 6.8E-45 T 29-03-2018 CVS48_RS04675 b44e3af283876e4cd5323ffc103c3513 334 SUPERFAMILY SSF102198 156 333 3.01E-9 T 29-03-2018 CVS48_RS04675 b44e3af283876e4cd5323ffc103c3513 334 SUPERFAMILY SSF102198 96 128 3.01E-9 T 29-03-2018 CVS48_RS04675 b44e3af283876e4cd5323ffc103c3513 334 Pfam PF04199 Putative cyclase 52 262 2.3E-14 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CVS48_RS19650 6babe23cc57e67151fdd1af852a6d34e 227 Pfam PF11010 Protein of unknown function (DUF2848) 25 218 2.2E-78 T 29-03-2018 IPR021269 Protein of unknown function DUF2848 CVS48_RS22585 b9f328778b59fa446dcbf69ecfbcf056 283 TIGRFAM TIGR02298 HpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1 281 1.5E-146 T 29-03-2018 IPR011984 3,4-dihydroxyphenylacetate 2,3-dioxygenase GO:0008687 KEGG: 00350+1.13.11.15 CVS48_RS22585 b9f328778b59fa446dcbf69ecfbcf056 283 SUPERFAMILY SSF53213 12 279 2.22E-53 T 29-03-2018 CVS48_RS22585 b9f328778b59fa446dcbf69ecfbcf056 283 Gene3D G3DSA:3.40.830.10 2 276 4.6E-52 T 29-03-2018 CVS48_RS22585 b9f328778b59fa446dcbf69ecfbcf056 283 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 279 5.4E-66 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CVS48_RS12270 b0479cf27ffe0f06a97d568cc7581fb9 213 Gene3D G3DSA:2.60.120.620 19 213 1.9E-5 T 29-03-2018 CVS48_RS12270 b0479cf27ffe0f06a97d568cc7581fb9 213 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 49 211 6.9E-60 T 29-03-2018 IPR018655 Protein of unknown function DUF2086 CVS48_RS09345 1e1542c23785dd31216e4f6336789a8b 262 Pfam PF03975 CheD chemotactic sensory transduction 65 167 1.2E-30 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CVS48_RS09345 1e1542c23785dd31216e4f6336789a8b 262 SUPERFAMILY SSF64438 23 169 5.86E-49 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CVS48_RS09345 1e1542c23785dd31216e4f6336789a8b 262 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 18 171 29.114 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CVS48_RS05365 7f50deffb557e26b081edb75fe6ee567 209 Pfam PF01810 LysE type translocator 16 203 1.3E-30 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS05365 7f50deffb557e26b081edb75fe6ee567 209 PIRSF PIRSF006324 1 207 7.2E-51 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS03160 9ada4cecbe9ade3450156d5eb0f84170 167 Pfam PF05433 Glycine zipper 2TM domain 76 115 2.1E-8 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CVS48_RS07185 46c08567e6cfe3ff240f713657f96d4c 218 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 61 193 1.8E-8 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component CVS48_RS07185 46c08567e6cfe3ff240f713657f96d4c 218 Gene3D G3DSA:3.40.50.10610 22 210 3.2E-30 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component CVS48_RS07185 46c08567e6cfe3ff240f713657f96d4c 218 SUPERFAMILY SSF159594 37 201 1.18E-24 T 29-03-2018 CVS48_RS02935 81e4973edee5f9f9d48efe5b85a67ca8 517 Pfam PF04293 SpoVR like protein 25 455 1.8E-172 T 29-03-2018 IPR007390 Sporulation stage V, protein R CVS48_RS27870 075949d7fa51d7960e95b6234dd86a1e 150 Pfam PF09980 Predicted membrane protein (DUF2214) 4 146 1.6E-52 T 29-03-2018 IPR018706 Protein of unknown function DUF2214, membrane CVS48_RS26385 63e3f7d6b42da3b7f503cfd111f9a440 642 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 21 642 33.208 T 29-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup CVS48_RS26385 63e3f7d6b42da3b7f503cfd111f9a440 642 Pfam PF02705 K+ potassium transporter 30 562 3.5E-202 T 29-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 CVS48_RS22325 0adcc8f50065dd034257f30344f435cd 384 Gene3D G3DSA:3.40.50.2300 150 313 4.4E-26 T 29-03-2018 CVS48_RS22325 0adcc8f50065dd034257f30344f435cd 384 Pfam PF13458 Periplasmic binding protein 24 373 2.6E-45 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS22325 0adcc8f50065dd034257f30344f435cd 384 Gene3D G3DSA:3.40.50.2300 9 149 1.4E-16 T 29-03-2018 CVS48_RS22325 0adcc8f50065dd034257f30344f435cd 384 SUPERFAMILY SSF53822 24 381 1.41E-65 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS18015 2b64156a7ff5bb108c32fdc1bab919e8 217 SUPERFAMILY SSF161098 11 204 1.7E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS18015 2b64156a7ff5bb108c32fdc1bab919e8 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 108 3.4E-28 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CVS48_RS18015 2b64156a7ff5bb108c32fdc1bab919e8 217 Gene3D G3DSA:1.10.3720.10 2 217 2.7E-43 T 29-03-2018 CVS48_RS18015 2b64156a7ff5bb108c32fdc1bab919e8 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 212 9.5E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS21700 4faab7a441e2f48fcf9c7aaa4e3d1a8d 319 PIRSF PIRSF017082 1 319 1.0E-61 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21700 4faab7a441e2f48fcf9c7aaa4e3d1a8d 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 290 3.4E-58 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS21700 4faab7a441e2f48fcf9c7aaa4e3d1a8d 319 Gene3D G3DSA:3.40.190.10 120 235 5.0E-10 T 29-03-2018 CVS48_RS21700 4faab7a441e2f48fcf9c7aaa4e3d1a8d 319 SUPERFAMILY SSF53850 118 276 6.59E-9 T 29-03-2018 CVS48_RS11685 1a4309e6c34e90cbf35458d7615223ae 424 Pfam PF03929 PepSY-associated TM region 27 364 1.5E-49 T 29-03-2018 IPR005625 PepSY-associated TM protein CVS48_RS18940 97aea0d65e4184e31733992447eff4f5 139 Gene3D G3DSA:1.10.10.10 25 81 0.001 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS23200 7079e9b9cd5d6e52fa9d22209809a6e3 82 SUPERFAMILY SSF47598 2 43 1.67E-10 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CVS48_RS23200 7079e9b9cd5d6e52fa9d22209809a6e3 82 Gene3D G3DSA:1.10.1220.10 4 44 1.8E-13 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CVS48_RS18690 ada1ac9f3d08306b2a5f038cb09f036e 163 SUPERFAMILY SSF54427 10 163 7.49E-46 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS18690 ada1ac9f3d08306b2a5f038cb09f036e 163 Pfam PF00866 Ring hydroxylating beta subunit 25 154 3.7E-15 T 29-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CVS48_RS18690 ada1ac9f3d08306b2a5f038cb09f036e 163 Gene3D G3DSA:3.10.450.50 2 163 8.7E-32 T 29-03-2018 CVS48_RS22540 cb211bbc6daee5b4b13edb35af133388 309 Gene3D G3DSA:3.20.20.70 7 306 1.0E-27 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS22540 cb211bbc6daee5b4b13edb35af133388 309 Pfam PF00701 Dihydrodipicolinate synthetase family 57 291 4.1E-5 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS22540 cb211bbc6daee5b4b13edb35af133388 309 SMART SM01130 10 303 3.3E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CVS48_RS22540 cb211bbc6daee5b4b13edb35af133388 309 SUPERFAMILY SSF51569 14 299 8.37E-29 T 29-03-2018 CVS48_RS12140 a687eedf8ec43db007c19517693e97db 205 Gene3D G3DSA:2.60.40.10 36 121 1.2E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CVS48_RS25160 13848d971d66cc41ddcc46a3889eb1bd 191 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 155 1.0E-30 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS08515 494a6cd11172623e69f3b738e35b1594 230 Pfam PF12059 Protein of unknown function (DUF3540) 33 230 2.7E-47 T 29-03-2018 IPR021927 Protein of unknown function DUF3540 CVS48_RS05445 db0cb2059bdc73ca895485d6cfa32723 113 Pfam PF08895 Domain of unknown function (DUF1840) 1 107 1.4E-27 T 29-03-2018 IPR014991 Protein of unknown function DUF1840 CVS48_RS21420 aa8468e4af85b47a296e4fa8e824683a 626 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 213 621 1.4E-96 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS21420 aa8468e4af85b47a296e4fa8e824683a 626 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 46 172 7.4E-28 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS21420 aa8468e4af85b47a296e4fa8e824683a 626 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 222 622 3.5E-86 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS02770 689c13e13a602def6307f3f2663e4029 169 Pfam PF05232 Chlorhexidine efflux transporter 11 74 1.7E-24 T 29-03-2018 IPR007896 Chlorhexidine efflux transporter CVS48_RS02770 689c13e13a602def6307f3f2663e4029 169 Pfam PF05232 Chlorhexidine efflux transporter 79 142 4.0E-26 T 29-03-2018 IPR007896 Chlorhexidine efflux transporter CVS48_RS05530 d368607214258f1347400f5f1d27b007 124 Gene3D G3DSA:3.40.30.10 19 124 2.7E-17 T 29-03-2018 CVS48_RS05530 d368607214258f1347400f5f1d27b007 124 Pfam PF13417 Glutathione S-transferase, N-terminal domain 45 122 7.1E-13 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CVS48_RS05530 d368607214258f1347400f5f1d27b007 124 SUPERFAMILY SSF52833 44 122 7.37E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS20915 d8de207c88d6d188d8d11d7525f8dae1 342 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 327 7.9E-38 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CVS48_RS20915 d8de207c88d6d188d8d11d7525f8dae1 342 SUPERFAMILY SSF51726 7 341 1.27E-68 T 29-03-2018 CVS48_RS20915 d8de207c88d6d188d8d11d7525f8dae1 342 Gene3D G3DSA:3.20.20.210 1 341 4.6E-90 T 29-03-2018 CVS48_RS20915 d8de207c88d6d188d8d11d7525f8dae1 342 PIRSF PIRSF005632 1 342 1.6E-200 T 29-03-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit CVS48_RS18615 e40cfea9dda18c771e0c2ec6670beb37 415 Gene3D G3DSA:1.20.1250.20 14 206 4.9E-14 T 29-03-2018 CVS48_RS18615 e40cfea9dda18c771e0c2ec6670beb37 415 Gene3D G3DSA:1.20.1250.20 215 414 9.4E-11 T 29-03-2018 CVS48_RS18615 e40cfea9dda18c771e0c2ec6670beb37 415 Pfam PF07690 Major Facilitator Superfamily 24 370 1.3E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS18615 e40cfea9dda18c771e0c2ec6670beb37 415 SUPERFAMILY SSF103473 8 410 1.22E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS24075 300bf2dcb6cbb1405d71aa59ebe6ffe1 287 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 6 284 17.73 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CVS48_RS24075 300bf2dcb6cbb1405d71aa59ebe6ffe1 287 Pfam PF02673 Bacitracin resistance protein BacA 11 278 1.3E-81 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CVS48_RS11955 e97bb4a62a0ed9be3ebfa6807893db06 254 Gene3D G3DSA:2.40.160.10 8 254 4.9E-5 T 29-03-2018 CVS48_RS11955 e97bb4a62a0ed9be3ebfa6807893db06 254 Pfam PF06629 MltA-interacting protein MipA 30 254 2.8E-46 T 29-03-2018 IPR010583 MltA-interacting MipA CVS48_RS05170 e30d64adc97e730156a8d461d358c023 258 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 10 245 1.5E-51 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CVS48_RS05170 e30d64adc97e730156a8d461d358c023 258 Gene3D G3DSA:3.40.1390.30 1 111 4.7E-23 T 29-03-2018 CVS48_RS05170 e30d64adc97e730156a8d461d358c023 258 Gene3D G3DSA:3.40.1390.30 112 229 7.8E-30 T 29-03-2018 CVS48_RS05170 e30d64adc97e730156a8d461d358c023 258 SUPERFAMILY SSF102705 8 257 2.62E-72 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CVS48_RS05170 e30d64adc97e730156a8d461d358c023 258 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 9 257 2.3E-54 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.3E-20 T 29-03-2018 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 3.3E-20 T 29-03-2018 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 3.3E-20 T 29-03-2018 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 3.3E-20 T 29-03-2018 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 3.3E-20 T 29-03-2018 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 Gene3D G3DSA:3.50.50.60 4 355 4.0E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 Pfam PF01494 FAD binding domain 7 348 1.3E-22 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 SUPERFAMILY SSF51905 5 172 1.94E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 SUPERFAMILY SSF51905 273 371 1.94E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CVS48_RS09660 275dbeec7349dae7b5f1a90b0dea8759 385 SUPERFAMILY SSF54373 177 278 1.92E-8 T 29-03-2018 CVS48_RS27720 fc955e90c31bbc5b8e085d6a1ec2794b 107 Pfam PF11804 Protein of unknown function (DUF3325) 3 102 7.2E-35 T 29-03-2018 IPR021762 Protein of unknown function DUF3325 CVS48_RS20475 1bba57a7d77da0f99e2192b0043f10aa 269 Pfam PF02596 Uncharacterised ArCR, COG2043 19 225 5.2E-37 T 29-03-2018 IPR003748 Protein of unknown function DUF169 CVS48_RS21670 79c8e2f4cea5876ccf7fddf8b0e6ea7a 1306 SUPERFAMILY SSF52151 663 827 1.52E-8 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CVS48_RS21670 79c8e2f4cea5876ccf7fddf8b0e6ea7a 1306 Gene3D G3DSA:3.40.1090.10 9 133 1.0E-13 T 29-03-2018 CVS48_RS21670 79c8e2f4cea5876ccf7fddf8b0e6ea7a 1306 Gene3D G3DSA:3.40.1090.10 617 825 1.2E-6 T 29-03-2018 CVS48_RS21670 79c8e2f4cea5876ccf7fddf8b0e6ea7a 1306 SUPERFAMILY SSF52151 35 98 3.4E-12 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CVS48_RS21670 79c8e2f4cea5876ccf7fddf8b0e6ea7a 1306 Pfam PF01734 Patatin-like phospholipase 46 107 7.0E-8 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CVS48_RS21500 88de7c8a094e7f74e12c49b72b131454 297 Gene3D G3DSA:3.40.50.150 1 293 1.1E-6 T 29-03-2018 CVS48_RS21500 88de7c8a094e7f74e12c49b72b131454 297 SUPERFAMILY SSF53335 42 154 1.23E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS06345 9c917256e109bc2454fb01e9147da0b6 269 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 1 269 35.478 T 29-03-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CVS48_RS06345 9c917256e109bc2454fb01e9147da0b6 269 Gene3D G3DSA:3.30.360.10 135 239 1.7E-37 T 29-03-2018 CVS48_RS06345 9c917256e109bc2454fb01e9147da0b6 269 SUPERFAMILY SSF51735 1 154 1.5E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain CVS48_RS06345 9c917256e109bc2454fb01e9147da0b6 269 Pfam PF01958 Domain of unknown function DUF108 172 257 1.4E-32 T 29-03-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 CVS48_RS06345 9c917256e109bc2454fb01e9147da0b6 269 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 120 4.5E-23 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CVS48_RS06345 9c917256e109bc2454fb01e9147da0b6 269 Gene3D G3DSA:3.40.50.720 1 134 3.4E-14 T 29-03-2018 CVS48_RS06345 9c917256e109bc2454fb01e9147da0b6 269 PIRSF PIRSF005227 1 269 5.3E-80 T 29-03-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CVS48_RS06345 9c917256e109bc2454fb01e9147da0b6 269 SUPERFAMILY SSF55347 125 239 3.79E-31 T 29-03-2018 CVS48_RS24585 f8c337ac07452c9abfc7f3029975b541 342 SUPERFAMILY SSF51306 195 327 1.57E-17 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CVS48_RS24585 f8c337ac07452c9abfc7f3029975b541 342 Gene3D G3DSA:2.10.109.10 202 331 6.0E-18 T 29-03-2018 CVS48_RS24585 f8c337ac07452c9abfc7f3029975b541 342 Pfam PF00717 Peptidase S24-like 242 312 6.6E-6 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CVS48_RS21380 68b69f96a7077fc3275415636ece3e91 270 Pfam PF01226 Formate/nitrite transporter 8 257 7.5E-64 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CVS48_RS21380 68b69f96a7077fc3275415636ece3e91 270 Gene3D G3DSA:1.20.1080.10 4 270 1.2E-66 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CVS48_RS13270 f8b411817fd2758a20c82e1183912077 324 Gene3D G3DSA:3.40.190.10 126 234 1.5E-8 T 29-03-2018 CVS48_RS13270 f8b411817fd2758a20c82e1183912077 324 PIRSF PIRSF017082 1 324 4.4E-87 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS13270 f8b411817fd2758a20c82e1183912077 324 SUPERFAMILY SSF53850 115 282 1.41E-7 T 29-03-2018 CVS48_RS13270 f8b411817fd2758a20c82e1183912077 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 8.3E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS22735 0964ca163837ace43995448871d83453 232 Pfam PF05988 Bacterial protein of unknown function (DUF899) 3 221 3.4E-85 T 29-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like CVS48_RS22735 0964ca163837ace43995448871d83453 232 Gene3D G3DSA:3.40.30.10 18 191 2.6E-14 T 29-03-2018 CVS48_RS22735 0964ca163837ace43995448871d83453 232 SUPERFAMILY SSF52833 58 189 9.67E-10 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS26630 f906700f814d1ca1a10f1cafe906c071 105 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 11 94 2.8E-35 T 29-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CVS48_RS19660 f7ced7ce2ded92e79d7cb8c12d1fc308 206 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 36 165 1.4E-20 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS09190 86b37f867f5edef0a5ae22a0c6da7b5b 98 SUPERFAMILY SSF54909 1 90 6.43E-22 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS09190 86b37f867f5edef0a5ae22a0c6da7b5b 98 Pfam PF03795 YCII-related domain 1 88 2.2E-20 T 29-03-2018 IPR005545 YCII-related CVS48_RS09190 86b37f867f5edef0a5ae22a0c6da7b5b 98 Gene3D G3DSA:3.30.70.1060 1 91 1.4E-20 T 29-03-2018 CVS48_RS12125 acc849149171cc826ff7a96222662148 210 Gene3D G3DSA:3.40.50.620 50 188 8.1E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CVS48_RS12125 acc849149171cc826ff7a96222662148 210 Pfam PF02698 DUF218 domain 58 183 3.5E-22 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CVS48_RS27330 c55002a64b6c54b9b9fc75283c6966b9 416 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 24 202 5.7E-56 T 29-03-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 CVS48_RS27330 c55002a64b6c54b9b9fc75283c6966b9 416 Gene3D G3DSA:3.30.2010.10 201 283 2.8E-24 T 29-03-2018 CVS48_RS27330 c55002a64b6c54b9b9fc75283c6966b9 416 Pfam PF01435 Peptidase family M48 206 413 8.8E-38 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CVS48_RS23805 0d7e02c6f516263458955a75a264e10a 186 SUPERFAMILY SSF51161 24 182 1.66E-35 T 29-03-2018 IPR011004 Trimeric LpxA-like CVS48_RS23805 0d7e02c6f516263458955a75a264e10a 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 128 159 3.8E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CVS48_RS23805 0d7e02c6f516263458955a75a264e10a 186 Gene3D G3DSA:2.160.10.10 15 186 2.1E-28 T 29-03-2018 CVS48_RS15850 d1bb3f0ca8630fd503b9c06f31e84cc8 420 Pfam PF13458 Periplasmic binding protein 47 383 7.8E-94 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS15850 d1bb3f0ca8630fd503b9c06f31e84cc8 420 Gene3D G3DSA:3.40.50.2300 184 359 3.8E-31 T 29-03-2018 CVS48_RS15850 d1bb3f0ca8630fd503b9c06f31e84cc8 420 SUPERFAMILY SSF53822 47 418 2.12E-92 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS15850 d1bb3f0ca8630fd503b9c06f31e84cc8 420 Gene3D G3DSA:3.40.50.2300 37 183 2.2E-16 T 29-03-2018 CVS48_RS16470 fc3c9ef6db7d4edd9136997990d2c2d8 109 Gene3D G3DSA:3.30.70.1060 1 109 1.7E-12 T 29-03-2018 CVS48_RS16470 fc3c9ef6db7d4edd9136997990d2c2d8 109 Pfam PF03795 YCII-related domain 12 105 1.0E-5 T 29-03-2018 IPR005545 YCII-related CVS48_RS16470 fc3c9ef6db7d4edd9136997990d2c2d8 109 SUPERFAMILY SSF54909 21 106 1.29E-7 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS22455 a34e95d1906c0587d90e49af76c46645 207 Pfam PF01618 MotA/TolQ/ExbB proton channel family 67 186 1.2E-28 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CVS48_RS09385 db083973e19a579b48ace6af8b014ae1 391 SUPERFAMILY SSF53822 27 389 2.56E-76 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS09385 db083973e19a579b48ace6af8b014ae1 391 Pfam PF13458 Periplasmic binding protein 28 362 8.2E-66 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS09385 db083973e19a579b48ace6af8b014ae1 391 Gene3D G3DSA:3.40.50.2300 28 151 5.5E-17 T 29-03-2018 CVS48_RS09385 db083973e19a579b48ace6af8b014ae1 391 Gene3D G3DSA:3.40.50.2300 152 322 9.2E-33 T 29-03-2018 CVS48_RS15695 c4afa8720b8805674a1a629eaf239308 344 Gene3D G3DSA:1.20.1630.10 4 294 2.9E-37 T 29-03-2018 CVS48_RS15695 c4afa8720b8805674a1a629eaf239308 344 Pfam PF03916 Polysulphide reductase, NrfD 12 289 9.0E-13 T 29-03-2018 IPR005614 NrfD family CVS48_RS27110 219218eb22cc777d8409889db3a45fe8 262 Gene3D G3DSA:3.40.50.1820 19 261 4.1E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS27110 219218eb22cc777d8409889db3a45fe8 262 SUPERFAMILY SSF53474 26 262 9.47E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS27110 219218eb22cc777d8409889db3a45fe8 262 Pfam PF01738 Dienelactone hydrolase family 36 262 3.0E-64 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CVS48_RS10225 52a7c434f78609fe9d407b2c4b3e3055 246 Pfam PF00005 ABC transporter 21 174 8.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS10225 52a7c434f78609fe9d407b2c4b3e3055 246 SMART SM00382 29 240 2.3E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS10225 52a7c434f78609fe9d407b2c4b3e3055 246 SUPERFAMILY SSF52540 3 239 5.65E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS10225 52a7c434f78609fe9d407b2c4b3e3055 246 Gene3D G3DSA:3.40.50.300 1 244 4.3E-50 T 29-03-2018 CVS48_RS14565 09c4a79ba64807e2949502f83531b3bc 314 Pfam PF10671 Toxin co-regulated pilus biosynthesis protein Q 219 298 6.8E-22 T 29-03-2018 IPR018927 Toxin co-regulated pilus biosynthesis protein Q, C-terminal CVS48_RS14565 09c4a79ba64807e2949502f83531b3bc 314 Pfam PF03524 Conjugal transfer protein 36 113 1.7E-11 T 29-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX CVS48_RS00285 be6e87dc8cb874efb5739a64200c1988 696 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 49 686 2.5E-232 T 29-03-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily CVS48_RS00285 be6e87dc8cb874efb5739a64200c1988 696 Gene3D G3DSA:3.40.50.720 301 620 0.0014 T 29-03-2018 CVS48_RS00285 be6e87dc8cb874efb5739a64200c1988 696 Pfam PF00474 Sodium:solute symporter family 74 233 3.1E-28 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS00285 be6e87dc8cb874efb5739a64200c1988 696 Pfam PF00474 Sodium:solute symporter family 496 611 9.0E-16 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS12875 5a53b1524fd9c672ae88e73d79daee02 1180 Gene3D G3DSA:3.30.1330.60 991 1173 5.4E-16 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS12875 5a53b1524fd9c672ae88e73d79daee02 1180 Pfam PF05359 Domain of Unknown Function (DUF748) 561 701 1.4E-21 T 29-03-2018 IPR008023 Protein of unknown function DUF748 CVS48_RS12875 5a53b1524fd9c672ae88e73d79daee02 1180 Pfam PF05359 Domain of Unknown Function (DUF748) 786 932 3.5E-37 T 29-03-2018 IPR008023 Protein of unknown function DUF748 CVS48_RS12875 5a53b1524fd9c672ae88e73d79daee02 1180 Pfam PF05359 Domain of Unknown Function (DUF748) 157 310 8.0E-22 T 29-03-2018 IPR008023 Protein of unknown function DUF748 CVS48_RS02300 a7eab9f76f63fd7189ff6b1844f04047 95 SMART SM00994 4 43 0.0055 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CVS48_RS02300 a7eab9f76f63fd7189ff6b1844f04047 95 Pfam PF06689 ClpX C4-type zinc finger 6 38 6.5E-6 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CVS48_RS20410 d64f6443bd206cbd39ca536e96a75c37 604 Pfam PF01936 NYN domain 10 153 9.5E-33 T 29-03-2018 IPR021139 NYN domain, limkain-b1-type CVS48_RS20410 d64f6443bd206cbd39ca536e96a75c37 604 Gene3D G3DSA:3.40.50.1010 1 157 3.3E-30 T 29-03-2018 IPR029060 PIN domain-like CVS48_RS05820 fadb4167647b121ff14a0657beec0194 357 Gene3D G3DSA:1.10.3470.10 9 356 3.1E-36 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS05820 fadb4167647b121ff14a0657beec0194 357 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 342 2.8E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS02120 f7dad39f18e5074f633a7058272e30e0 211 Gene3D G3DSA:1.25.40.10 4 174 2.8E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS02120 f7dad39f18e5074f633a7058272e30e0 211 SUPERFAMILY SSF48452 24 91 2.38E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS08475 73bf7b2b16ab075f64df9a36faec44b6 198 Pfam PF14348 Domain of unknown function (DUF4400) 76 195 1.3E-18 T 29-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type CVS48_RS00125 30d158b4d5c304a424536aefcbc6794e 425 Pfam PF10011 Predicted membrane protein (DUF2254) 14 377 2.1E-102 T 29-03-2018 IPR018723 Protein of unknown function DUF2254, membrane CVS48_RS24550 720e9271fecd0c210dad74cc635e5402 274 Pfam PF13730 Helix-turn-helix domain 16 67 3.0E-12 T 29-03-2018 CVS48_RS10690 42f137950908d97de28ebb165e22d8aa 449 Pfam PF03023 MviN-like protein 44 443 6.3E-37 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CVS48_RS18245 a7a10f4e6f4537d5b31ea24a9cef375f 427 PIRSF PIRSF006066 3 427 8.4E-142 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS18245 a7a10f4e6f4537d5b31ea24a9cef375f 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 10 418 1.5E-107 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS18245 a7a10f4e6f4537d5b31ea24a9cef375f 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 20 423 1.0E-121 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 CVS48_RS06895 2d73f14c55c666e35568401dc3844cfc 400 Gene3D G3DSA:3.90.1150.10 276 400 6.2E-34 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CVS48_RS06895 2d73f14c55c666e35568401dc3844cfc 400 Gene3D G3DSA:3.40.640.10 60 275 4.7E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CVS48_RS06895 2d73f14c55c666e35568401dc3844cfc 400 SUPERFAMILY SSF53383 10 398 1.77E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CVS48_RS06895 2d73f14c55c666e35568401dc3844cfc 400 Pfam PF00155 Aminotransferase class I and II 49 387 3.9E-34 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CVS48_RS10630 532a7d11b27a8721d61d15e6b38ba37e 502 PIRSF PIRSF012702 1 500 5.1E-181 T 29-03-2018 IPR009197 Microcystin LR degradation protein MlrC CVS48_RS10630 532a7d11b27a8721d61d15e6b38ba37e 502 Pfam PF07171 MlrC C-terminus 304 481 7.2E-56 T 29-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CVS48_RS10630 532a7d11b27a8721d61d15e6b38ba37e 502 Pfam PF07364 Metallopeptidase family M81 2 292 4.8E-106 T 29-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CVS48_RS10630 532a7d11b27a8721d61d15e6b38ba37e 502 Gene3D G3DSA:3.20.20.70 77 189 0.12 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS10630 532a7d11b27a8721d61d15e6b38ba37e 502 Gene3D G3DSA:3.20.20.70 244 371 0.12 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CVS48_RS26310 dc1f4292c4275029233f7f2912dbd88a 313 Gene3D G3DSA:1.10.3720.10 23 302 1.3E-43 T 29-03-2018 CVS48_RS26310 dc1f4292c4275029233f7f2912dbd88a 313 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 72 2.6E-9 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS26310 dc1f4292c4275029233f7f2912dbd88a 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 313 2.0E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS26310 dc1f4292c4275029233f7f2912dbd88a 313 SUPERFAMILY SSF161098 94 293 2.75E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS16060 44238f6f4b7f8f8394a2f831ad48321e 322 Pfam PF16220 Domain of unknown function (DUF4880) 14 52 3.9E-13 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS16060 44238f6f4b7f8f8394a2f831ad48321e 322 Pfam PF04773 FecR protein 115 206 2.6E-20 T 29-03-2018 IPR006860 FecR protein CVS48_RS16060 44238f6f4b7f8f8394a2f831ad48321e 322 PIRSF PIRSF018266 4 317 3.3E-85 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS15320 5619542f1e565f133c3d6e170c7cca94 327 PIRSF PIRSF026166 1 326 2.1E-118 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter CVS48_RS15320 5619542f1e565f133c3d6e170c7cca94 327 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 7 314 3.9E-93 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter CVS48_RS19355 78b0bba711cecab642c34975c2024ed8 428 Pfam PF05159 Capsule polysaccharide biosynthesis protein 85 394 2.1E-77 T 29-03-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 CVS48_RS23975 3c2926fe2c5967b47e6731dc31fd8a7d 321 PIRSF PIRSF017082 1 320 1.1E-77 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23975 3c2926fe2c5967b47e6731dc31fd8a7d 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 316 8.6E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CVS48_RS23975 3c2926fe2c5967b47e6731dc31fd8a7d 321 Gene3D G3DSA:3.40.190.10 123 257 8.1E-10 T 29-03-2018 CVS48_RS23975 3c2926fe2c5967b47e6731dc31fd8a7d 321 SUPERFAMILY SSF53850 91 277 1.19E-9 T 29-03-2018 CVS48_RS28635 8873f772502daa708f0a38d01d82b83d 109 Pfam PF10993 Protein of unknown function (DUF2818) 6 102 2.6E-34 T 29-03-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane CVS48_RS28635 8873f772502daa708f0a38d01d82b83d 109 PIRSF PIRSF019883 1 106 2.6E-43 T 29-03-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane CVS48_RS15490 d71d8761da4459715d6e4ec8115f53dc 219 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 84 170 2.9E-11 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CVS48_RS15490 d71d8761da4459715d6e4ec8115f53dc 219 Gene3D G3DSA:3.90.470.20 93 185 1.5E-11 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CVS48_RS15490 d71d8761da4459715d6e4ec8115f53dc 219 SUPERFAMILY SSF56214 83 195 6.54E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CVS48_RS15490 d71d8761da4459715d6e4ec8115f53dc 219 Gene3D G3DSA:3.90.470.20 3 92 3.3E-6 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CVS48_RS24905 c5afe280426cfb18a940b95dfd1da273 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 255 1.5E-48 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS24905 c5afe280426cfb18a940b95dfd1da273 263 Gene3D G3DSA:3.90.226.10 3 261 2.2E-69 T 29-03-2018 CVS48_RS24905 c5afe280426cfb18a940b95dfd1da273 263 SUPERFAMILY SSF52096 9 259 3.89E-71 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS08410 41f971c1cfdc8c0283b582a8efce0a0e 269 Pfam PF04335 VirB8 protein 46 253 7.8E-21 T 29-03-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 CVS48_RS12575 e6597ac917a74cad4d7088bb7a77ea49 313 SUPERFAMILY SSF81345 4 308 6.15E-75 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CVS48_RS12575 e6597ac917a74cad4d7088bb7a77ea49 313 Pfam PF01032 FecCD transport family 3 308 1.2E-82 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CVS48_RS12575 e6597ac917a74cad4d7088bb7a77ea49 313 Gene3D G3DSA:1.10.3470.10 1 313 6.8E-64 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS02160 7038ba5f9a59de9fae9be34c53a0c93e 326 Pfam PF13503 Domain of unknown function (DUF4123) 29 165 8.4E-14 T 29-03-2018 IPR025391 Domain of unknown function DUF4123 CVS48_RS10405 fead6812c331218b1c4ef41e1849920a 54 Pfam PF10617 Protein of unknown function (DUF2474) 17 54 9.1E-15 T 29-03-2018 IPR018895 Protein of unknown function DUF2474 CVS48_RS10125 16822a9ec3ed8fa493e62326f8257050 562 Gene3D G3DSA:1.10.287.70 5 395 0.23 T 29-03-2018 CVS48_RS10125 16822a9ec3ed8fa493e62326f8257050 562 Pfam PF00474 Sodium:solute symporter family 48 423 9.7E-26 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS20940 76a0bc4449b415e3281053f146ab02a1 204 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 9 193 3.4E-79 T 29-03-2018 IPR018715 Protein of unknown function DUF2239 CVS48_RS13180 b77f1d5180973e7d80042fbaf371fc2b 109 SUPERFAMILY SSF51182 30 105 8.1E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS13180 b77f1d5180973e7d80042fbaf371fc2b 109 Gene3D G3DSA:2.60.120.10 2 109 6.0E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS15070 e8570e2d17c194afc4625bba12da9aa8 96 Pfam PF07883 Cupin domain 22 91 9.8E-7 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS15070 e8570e2d17c194afc4625bba12da9aa8 96 SUPERFAMILY SSF51182 3 91 1.39E-12 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS15070 e8570e2d17c194afc4625bba12da9aa8 96 Gene3D G3DSA:2.60.120.10 3 96 5.6E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS27725 5c4419e28865a94da5d6e56e806d7393 555 Pfam PF03929 PepSY-associated TM region 20 374 3.0E-66 T 29-03-2018 IPR005625 PepSY-associated TM protein CVS48_RS14435 d173f1eae3c25b0936400b733e3bfab9 152 SUPERFAMILY SSF46626 28 124 2.47E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS14435 d173f1eae3c25b0936400b733e3bfab9 152 Gene3D G3DSA:1.10.760.10 2 124 3.3E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CVS48_RS21485 8ea6633fbd4d084a9a1932403d93d5e3 64 Gene3D G3DSA:1.10.1220.10 5 47 1.5E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CVS48_RS21485 8ea6633fbd4d084a9a1932403d93d5e3 64 SUPERFAMILY SSF47598 7 50 2.38E-5 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CVS48_RS04265 c602669b04cd541d46af523d35ff0607 125 Pfam PF05610 Protein of unknown function (DUF779) 17 110 4.4E-48 T 29-03-2018 IPR008497 Protein of unknown function DUF779 CVS48_RS04265 c602669b04cd541d46af523d35ff0607 125 PIRSF PIRSF009151 1 124 1.5E-58 T 29-03-2018 IPR008497 Protein of unknown function DUF779 CVS48_RS18425 18ad36ef443e07cc9f65f3ce2740f959 334 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 26 301 1.2E-11 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CVS48_RS04600 886c9b602c1e52b0241b80bf71b4c3cf 404 SUPERFAMILY SSF103473 8 389 1.57E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS04600 886c9b602c1e52b0241b80bf71b4c3cf 404 Gene3D G3DSA:1.20.1250.20 3 194 9.0E-21 T 29-03-2018 CVS48_RS04600 886c9b602c1e52b0241b80bf71b4c3cf 404 Gene3D G3DSA:1.20.1250.20 199 392 7.3E-12 T 29-03-2018 CVS48_RS04600 886c9b602c1e52b0241b80bf71b4c3cf 404 Pfam PF07690 Major Facilitator Superfamily 18 326 6.4E-28 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CVS48_RS16330 8f3309cf24911123a49bdb351e4d3a0a 153 Gene3D G3DSA:3.40.630.30 8 148 1.1E-7 T 29-03-2018 CVS48_RS16330 8f3309cf24911123a49bdb351e4d3a0a 153 SUPERFAMILY SSF55729 14 139 4.68E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CVS48_RS23140 dba790b08113903fde28d01594d168fa 78 Pfam PF05751 FixH 16 44 6.4E-5 T 29-03-2018 IPR008620 Nitrogen fixation protein FixH CVS48_RS12725 488e136b0e0e6db16b621f20b90b1fe8 504 Pfam PF08811 Protein of unknown function (DUF1800) 10 501 5.6E-86 T 29-03-2018 IPR014917 Protein of unknown function DUF1800 CVS48_RS09100 eaacf339aa30bfbb06eb58adf444a01f 357 Gene3D G3DSA:1.25.40.10 3 356 1.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CVS48_RS23090 ec35ef7bfd9061981e88251eb3530cd5 130 Pfam PF13767 Domain of unknown function (DUF4168) 45 121 2.9E-18 T 29-03-2018 IPR025433 Domain of unknown function DUF4168 CVS48_RS08680 2984034173cddce129103f83f96f4212 155 Gene3D G3DSA:1.10.357.10 20 139 8.9E-4 T 29-03-2018 CVS48_RS11585 8de6821af773625bc79ddb417f7bde1f 356 SUPERFAMILY SSF102198 100 130 3.27E-10 T 29-03-2018 CVS48_RS11585 8de6821af773625bc79ddb417f7bde1f 356 SUPERFAMILY SSF102198 172 355 3.27E-10 T 29-03-2018 CVS48_RS11585 8de6821af773625bc79ddb417f7bde1f 356 Pfam PF04199 Putative cyclase 94 279 5.4E-13 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CVS48_RS11585 8de6821af773625bc79ddb417f7bde1f 356 Gene3D G3DSA:3.50.30.50 42 356 4.1E-46 T 29-03-2018 CVS48_RS01380 28ee116bce89b009a70cf54a60dd7682 112 Gene3D G3DSA:3.30.70.260 21 108 8.5E-4 T 29-03-2018 CVS48_RS00615 e29dc8ba25e6aa0a56df9033a5bc9c8e 210 Pfam PF08808 RES domain 29 177 1.3E-21 T 29-03-2018 IPR014914 RES domain CVS48_RS00615 e29dc8ba25e6aa0a56df9033a5bc9c8e 210 SMART SM00953 28 175 3.2E-15 T 29-03-2018 IPR014914 RES domain CVS48_RS22460 04c3009ebde259cf9ed4ec1a44a50ee2 137 Gene3D G3DSA:3.40.50.2300 11 135 4.3E-4 T 29-03-2018 CVS48_RS22460 04c3009ebde259cf9ed4ec1a44a50ee2 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 134 4.8E-26 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CVS48_RS00655 108a81cb361070048b72c9d168c99705 255 SUPERFAMILY SSF52833 28 229 6.97E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS00655 108a81cb361070048b72c9d168c99705 255 Gene3D G3DSA:3.40.30.10 62 240 2.4E-25 T 29-03-2018 CVS48_RS00655 108a81cb361070048b72c9d168c99705 255 Pfam PF13462 Thioredoxin 65 208 3.7E-15 T 29-03-2018 IPR012336 Thioredoxin-like fold CVS48_RS23575 2e9a678b2350c681c4f5ef484066f82b 161 Pfam PF12266 Protein of unknown function (DUF3613) 91 153 2.4E-12 T 29-03-2018 IPR022053 Protein of unknown function DUF3613 CVS48_RS22750 bd14df6d82d9d39fb849ffe2b7927712 198 SUPERFAMILY SSF55811 17 183 2.03E-49 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CVS48_RS22750 bd14df6d82d9d39fb849ffe2b7927712 198 Pfam PF00293 NUDIX domain 52 160 9.8E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CVS48_RS22750 bd14df6d82d9d39fb849ffe2b7927712 198 Gene3D G3DSA:3.90.79.10 2 191 3.8E-42 T 29-03-2018 CVS48_RS20890 0a3ae2b0985e91a966a1b1723394e9af 88 Pfam PF08808 RES domain 3 56 3.3E-8 T 29-03-2018 IPR014914 RES domain CVS48_RS17730 31c7e44a1849b85aa333302891f0f3ed 440 Gene3D G3DSA:2.120.10.10 265 433 3.8E-4 T 29-03-2018 CVS48_RS17730 31c7e44a1849b85aa333302891f0f3ed 440 SUPERFAMILY SSF50939 355 433 1.47E-8 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CVS48_RS17730 31c7e44a1849b85aa333302891f0f3ed 440 SUPERFAMILY SSF50939 143 225 1.47E-8 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CVS48_RS17730 31c7e44a1849b85aa333302891f0f3ed 440 Gene3D G3DSA:2.120.10.10 78 237 8.6E-7 T 29-03-2018 CVS48_RS28175 a560ec9dfba4cda493479fe75fc4b564 107 PIRSF PIRSF020408 5 106 7.3E-42 T 29-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 CVS48_RS28175 a560ec9dfba4cda493479fe75fc4b564 107 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 6 97 9.0E-18 T 29-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 CVS48_RS02595 625678fa4742ac151184b1f09fa9eadb 253 Pfam PF04402 Protein of unknown function (DUF541) 52 249 2.6E-25 T 29-03-2018 IPR007497 Protein of unknown function DUF541 CVS48_RS12415 b00acbad722d9d7ec0f57d9cd50e85a8 118 Pfam PF13663 Domain of unknown function (DUF4148) 1 71 1.1E-9 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS12415 b00acbad722d9d7ec0f57d9cd50e85a8 118 Pfam PF13663 Domain of unknown function (DUF4148) 80 107 7.8E-7 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 Pfam PF04972 BON domain 28 71 0.0026 T 29-03-2018 IPR007055 BON domain CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 SUPERFAMILY SSF103088 155 261 1.83E-33 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 Pfam PF00691 OmpA family 162 256 3.5E-24 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 225 244 2.8E-7 T 29-03-2018 CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 245 264 2.8E-7 T 29-03-2018 CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 207 224 2.8E-7 T 29-03-2018 CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 Gene3D G3DSA:3.30.1330.60 80 264 1.8E-37 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 PRINTS PR01021 OMPA domain signature 207 223 5.4E-12 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 PRINTS PR01021 OMPA domain signature 192 207 5.4E-12 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS02195 a13b50626c6a714ce0eea6101c3279ad 264 PRINTS PR01021 OMPA domain signature 162 184 5.4E-12 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CVS48_RS28515 2890c925fc00adbfffcd076b685ba98e 387 SUPERFAMILY SSF53822 26 383 1.91E-74 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CVS48_RS28515 2890c925fc00adbfffcd076b685ba98e 387 Gene3D G3DSA:3.40.50.2300 9 153 7.5E-18 T 29-03-2018 CVS48_RS28515 2890c925fc00adbfffcd076b685ba98e 387 Pfam PF13458 Periplasmic binding protein 25 379 1.4E-49 T 29-03-2018 IPR028081 Leucine-binding protein domain CVS48_RS28515 2890c925fc00adbfffcd076b685ba98e 387 Gene3D G3DSA:3.40.50.2300 154 282 1.8E-27 T 29-03-2018 CVS48_RS28515 2890c925fc00adbfffcd076b685ba98e 387 Gene3D G3DSA:3.40.50.2300 283 367 7.8E-7 T 29-03-2018 CVS48_RS07310 445c8292f5d212cdc0e29e41c82742dd 298 PIRSF PIRSF026649 1 279 1.9E-79 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CVS48_RS07310 445c8292f5d212cdc0e29e41c82742dd 298 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 271 1.2E-34 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CVS48_RS06910 a668b2042622aea098346b3c9c2a3ea7 258 Pfam PF04116 Fatty acid hydroxylase superfamily 105 234 4.0E-22 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CVS48_RS06675 49eb80688ffb2e7639cf8bd373c7636e 186 Pfam PF04965 Gene 25-like lysozyme 56 160 1.8E-21 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD CVS48_RS06675 49eb80688ffb2e7639cf8bd373c7636e 186 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 28 179 4.0E-22 T 29-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein CVS48_RS06675 49eb80688ffb2e7639cf8bd373c7636e 186 SUPERFAMILY SSF160719 56 171 3.53E-9 T 29-03-2018 CVS48_RS06675 49eb80688ffb2e7639cf8bd373c7636e 186 Gene3D G3DSA:3.10.450.40 24 175 4.9E-23 T 29-03-2018 CVS48_RS27115 edd8b97255fd78e4713db314be76ec58 279 Pfam PF02535 ZIP Zinc transporter 91 250 1.5E-23 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CVS48_RS27115 edd8b97255fd78e4713db314be76ec58 279 Gene3D G3DSA:1.20.1640.10 4 256 0.0013 T 29-03-2018 CVS48_RS20420 736e3bd967eb22030ddc3c5a8361e738 325 Gene3D G3DSA:3.30.1330.60 9 323 4.1E-39 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS20420 736e3bd967eb22030ddc3c5a8361e738 325 Pfam PF00691 OmpA family 191 289 1.8E-19 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS20420 736e3bd967eb22030ddc3c5a8361e738 325 SUPERFAMILY SSF103088 180 295 1.7E-30 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS20420 736e3bd967eb22030ddc3c5a8361e738 325 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 50 81 1.4E-7 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CVS48_RS18790 9b111ba28a5d8238ed1088169b712720 227 SUPERFAMILY SSF53448 2 194 2.53E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS18790 9b111ba28a5d8238ed1088169b712720 227 Pfam PF00535 Glycosyl transferase family 2 4 145 8.7E-11 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CVS48_RS18790 9b111ba28a5d8238ed1088169b712720 227 Gene3D G3DSA:3.90.550.10 1 210 8.0E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CVS48_RS25250 c432bf9db55f7aeace5868a6bdd2a5ed 253 SUPERFAMILY SSF52096 2 248 2.87E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS25250 c432bf9db55f7aeace5868a6bdd2a5ed 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 231 4.4E-50 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS25250 c432bf9db55f7aeace5868a6bdd2a5ed 253 Gene3D G3DSA:3.90.226.10 1 252 6.2E-75 T 29-03-2018 CVS48_RS26805 22708131b16865d11a18e12bbb0375e7 239 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 191 1.6E-70 T 29-03-2018 IPR022301 Integral membrane protein YjbE CVS48_RS26805 22708131b16865d11a18e12bbb0375e7 239 Pfam PF03741 Integral membrane protein TerC family 14 190 3.1E-43 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CVS48_RS20765 b66de0f9cd023a89d386bef50a39ebd3 345 Gene3D G3DSA:3.60.15.10 62 332 1.6E-49 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS20765 b66de0f9cd023a89d386bef50a39ebd3 345 SUPERFAMILY SSF56281 79 305 2.44E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS20765 b66de0f9cd023a89d386bef50a39ebd3 345 Pfam PF12706 Beta-lactamase superfamily domain 96 288 1.5E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CVS48_RS14830 dd4e2d8013d39c0625650bc4a76159f0 458 Pfam PF00263 Bacterial type II and III secretion system protein 240 396 3.3E-43 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CVS48_RS14830 dd4e2d8013d39c0625650bc4a76159f0 458 PRINTS PR00811 Bacterial general secretion pathway protein D signature 236 260 1.4E-11 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS14830 dd4e2d8013d39c0625650bc4a76159f0 458 PRINTS PR00811 Bacterial general secretion pathway protein D signature 163 173 1.4E-11 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS14830 dd4e2d8013d39c0625650bc4a76159f0 458 PRINTS PR00811 Bacterial general secretion pathway protein D signature 361 379 1.4E-11 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS14830 dd4e2d8013d39c0625650bc4a76159f0 458 PRINTS PR00811 Bacterial general secretion pathway protein D signature 384 398 1.4E-11 T 29-03-2018 IPR001775 GspD/PilQ family CVS48_RS14830 dd4e2d8013d39c0625650bc4a76159f0 458 Pfam PF13629 Pilus formation protein N terminal region 28 95 5.0E-15 T 29-03-2018 IPR032789 Pilus formation protein, N-terminal CVS48_RS24400 114920d182fc771020c0d9c9b54e4803 103 Gene3D G3DSA:2.40.10.180 1 103 3.3E-5 T 29-03-2018 CVS48_RS10480 b3af38dcf4b4098a2306910769afcc65 389 Pfam PF01757 Acyltransferase family 4 335 4.3E-16 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CVS48_RS10295 465cd77aff9f0cc4209c5b09987d9e2d 114 SUPERFAMILY SSF53098 8 100 1.06E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CVS48_RS01265 2c8cd1f385a15affd3acf65282fa6443 133 Pfam PF07681 DoxX 11 87 3.8E-17 T 29-03-2018 IPR032808 DoxX family CVS48_RS07535 e743ae0214c933cf11e0fce09f4a41ca 284 Pfam PF00005 ABC transporter 38 189 3.2E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS07535 e743ae0214c933cf11e0fce09f4a41ca 284 SMART SM00382 47 239 4.4E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS07535 e743ae0214c933cf11e0fce09f4a41ca 284 SUPERFAMILY SSF52540 20 261 6.21E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07535 e743ae0214c933cf11e0fce09f4a41ca 284 Gene3D G3DSA:3.40.50.300 16 263 2.8E-48 T 29-03-2018 CVS48_RS06995 2d79744a820fee51dd077e00b97cf903 354 Pfam PF00953 Glycosyl transferase family 4 77 233 9.9E-32 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CVS48_RS24180 89146928e043e7ac0c2960a2f8483837 180 SUPERFAMILY SSF54909 5 102 2.91E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CVS48_RS24180 89146928e043e7ac0c2960a2f8483837 180 Gene3D G3DSA:3.30.70.100 8 102 1.8E-14 T 29-03-2018 CVS48_RS15135 ed40e75dac53490c4a610e866446b8e4 133 Gene3D G3DSA:3.40.50.510 2 133 1.1E-27 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CVS48_RS15135 ed40e75dac53490c4a610e866446b8e4 133 Pfam PF03610 PTS system fructose IIA component 4 111 9.4E-16 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CVS48_RS15135 ed40e75dac53490c4a610e866446b8e4 133 SUPERFAMILY SSF53062 1 132 1.96E-24 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CVS48_RS08225 05da4c22cbc2c81403e21a9aaeb8a2ea 111 Pfam PF13663 Domain of unknown function (DUF4148) 1 61 1.5E-5 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS22200 42ce2b7c5708a486418fc886ebe887cd 308 Pfam PF16220 Domain of unknown function (DUF4880) 13 55 1.9E-10 T 29-03-2018 IPR032623 FecR, N-terminal CVS48_RS22200 42ce2b7c5708a486418fc886ebe887cd 308 PIRSF PIRSF018266 3 308 1.7E-60 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CVS48_RS22200 42ce2b7c5708a486418fc886ebe887cd 308 Pfam PF04773 FecR protein 107 192 9.3E-16 T 29-03-2018 IPR006860 FecR protein CVS48_RS25750 67d722e593c5ead1776c9c4db5472d30 296 Pfam PF05067 Manganese containing catalase 1 288 6.1E-86 T 29-03-2018 IPR007760 Manganese catalase CVS48_RS25750 67d722e593c5ead1776c9c4db5472d30 296 SUPERFAMILY SSF47240 1 287 7.22E-84 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS25750 67d722e593c5ead1776c9c4db5472d30 296 Gene3D G3DSA:1.20.1260.10 1 200 4.7E-64 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS16490 9278ed8ecf2450d24e030397e87bd7ca 204 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 10 55 2.5E-11 T 29-03-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin CVS48_RS07825 fea431d3f5742226f3fc8039bd5ab65a 127 Pfam PF13663 Domain of unknown function (DUF4148) 91 123 2.3E-8 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS07825 fea431d3f5742226f3fc8039bd5ab65a 127 Pfam PF13663 Domain of unknown function (DUF4148) 1 51 3.3E-12 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS07825 fea431d3f5742226f3fc8039bd5ab65a 127 Pfam PF13663 Domain of unknown function (DUF4148) 56 86 5.0E-8 T 29-03-2018 IPR025421 Protein of unknown function DUF4148 CVS48_RS24825 a9ed50c68941bd2f2cd39258cc5192c3 142 Pfam PF11681 Protein of unknown function (DUF3277) 28 132 2.9E-9 T 29-03-2018 IPR021695 Bacteriophage rv5, Orf52 CVS48_RS06585 90cee16ac4330f41526f11178f2e5293 115 SUPERFAMILY SSF54913 5 107 1.22E-33 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CVS48_RS06585 90cee16ac4330f41526f11178f2e5293 115 Pfam PF03091 CutA1 divalent ion tolerance protein 9 106 1.7E-28 T 29-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CVS48_RS06585 90cee16ac4330f41526f11178f2e5293 115 Gene3D G3DSA:3.30.70.120 5 111 5.0E-32 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CVS48_RS14475 e66789a3e341dcdae8059962facc7aeb 200 Pfam PF14317 YcxB-like protein 127 176 3.1E-11 T 29-03-2018 IPR025588 YcxB-like protein CVS48_RS13385 8c3e0ebe968e042ac06096e10205900f 279 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 4 50 2.2E-7 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CVS48_RS13385 8c3e0ebe968e042ac06096e10205900f 279 SUPERFAMILY SSF161098 69 256 6.54E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13385 8c3e0ebe968e042ac06096e10205900f 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 274 8.8E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS13385 8c3e0ebe968e042ac06096e10205900f 279 Gene3D G3DSA:1.10.3720.10 2 263 3.9E-40 T 29-03-2018 CVS48_RS04785 32dbcda2d95f6c524b8e0e1e58ef71d2 110 SMART SM00834 1 41 4.5E-16 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CVS48_RS04785 32dbcda2d95f6c524b8e0e1e58ef71d2 110 Pfam PF09723 Zinc ribbon domain 1 38 1.9E-13 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CVS48_RS04785 32dbcda2d95f6c524b8e0e1e58ef71d2 110 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 45 1.7E-16 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CVS48_RS23555 ca6a0628a53b1c7e3ec197f6247bbdf4 152 Pfam PF06676 Protein of unknown function (DUF1178) 4 144 3.8E-51 T 29-03-2018 IPR009562 Protein of unknown function DUF1178 CVS48_RS23555 ca6a0628a53b1c7e3ec197f6247bbdf4 152 PIRSF PIRSF032131 3 150 1.9E-47 T 29-03-2018 IPR009562 Protein of unknown function DUF1178 CVS48_RS03240 c75a9df16eb50ab207324fe5f7116c87 298 Gene3D G3DSA:3.30.1150.10 62 297 2.8E-20 T 29-03-2018 CVS48_RS03240 c75a9df16eb50ab207324fe5f7116c87 298 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 213 288 1.6E-13 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CVS48_RS03240 c75a9df16eb50ab207324fe5f7116c87 298 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 212 288 1.5E-12 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CVS48_RS03240 c75a9df16eb50ab207324fe5f7116c87 298 SUPERFAMILY SSF74653 180 288 1.44E-17 T 29-03-2018 CVS48_RS23945 f180d3f157063d29c6709890d98772c6 375 Pfam PF12698 ABC-2 family transporter protein 26 364 1.6E-32 T 29-03-2018 CVS48_RS23945 f180d3f157063d29c6709890d98772c6 375 Gene3D G3DSA:3.40.1710.10 41 194 1.4E-22 T 29-03-2018 CVS48_RS12810 e3496e44ddd00cd8f58f961debdb8b73 85 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 5 71 3.8E-28 T 29-03-2018 IPR021074 Formate dehydrogenase, delta subunit CVS48_RS07940 801c968d7c2bd6825e060f435ff1b207 196 Pfam PF14334 Domain of unknown function (DUF4390) 29 184 3.7E-50 T 29-03-2018 IPR025500 Protein of unknown function DUF4390 CVS48_RS08370 2966e20fe93a721b902852c9fce8b067 364 Pfam PF00482 Type II secretion system (T2SS), protein F 28 156 4.2E-13 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS08370 2966e20fe93a721b902852c9fce8b067 364 Pfam PF00482 Type II secretion system (T2SS), protein F 231 351 2.7E-9 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS19095 93dd7256c05c91eac2653661f7f077fa 143 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 86 128 3.8E-10 T 29-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 CVS48_RS25055 e8c26e324eb00b5ee16306837f681515 130 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 117 5.3E-19 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CVS48_RS25055 e8c26e324eb00b5ee16306837f681515 130 SUPERFAMILY SSF69118 4 122 1.11E-31 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS25055 e8c26e324eb00b5ee16306837f681515 130 Gene3D G3DSA:1.20.1290.10 7 130 3.7E-30 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CVS48_RS20590 0fa1bf732d826219f1ffb255fe1e567d 391 Pfam PF01594 AI-2E family transporter 51 379 1.6E-36 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CVS48_RS07030 6477e847abb74415bebe1e3b73f0d0e6 599 SMART SM00382 377 546 3.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS07030 6477e847abb74415bebe1e3b73f0d0e6 599 Gene3D G3DSA:3.40.50.300 330 573 6.1E-44 T 29-03-2018 CVS48_RS07030 6477e847abb74415bebe1e3b73f0d0e6 599 SUPERFAMILY SSF52540 354 562 8.52E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS07030 6477e847abb74415bebe1e3b73f0d0e6 599 Pfam PF00005 ABC transporter 368 497 8.2E-16 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS05470 8780772f017ddc6cd2faa86770e12698 327 SUPERFAMILY SSF53474 75 323 5.21E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS05470 8780772f017ddc6cd2faa86770e12698 327 Gene3D G3DSA:3.40.50.1820 2 326 5.1E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS02015 ab8cfea81dd0931445fa44ce658b50ce 799 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 27 766 20.204 T 29-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 CVS48_RS02015 ab8cfea81dd0931445fa44ce658b50ce 799 Pfam PF04453 Organic solvent tolerance protein 303 693 9.8E-102 T 29-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 CVS48_RS02015 ab8cfea81dd0931445fa44ce658b50ce 799 Gene3D G3DSA:2.60.450.10 57 211 1.1E-13 T 29-03-2018 CVS48_RS21475 21895d67c9122c212d6b822fd266f1d3 875 Pfam PF04851 Type III restriction enzyme, res subunit 6 238 5.3E-14 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CVS48_RS21475 21895d67c9122c212d6b822fd266f1d3 875 Gene3D G3DSA:3.40.50.300 6 261 5.8E-12 T 29-03-2018 CVS48_RS21475 21895d67c9122c212d6b822fd266f1d3 875 SUPERFAMILY SSF52540 59 168 1.0E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21475 21895d67c9122c212d6b822fd266f1d3 875 SUPERFAMILY SSF52540 336 404 1.0E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21475 21895d67c9122c212d6b822fd266f1d3 875 SUPERFAMILY SSF52540 198 239 1.0E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS21415 19f99a1bcd9bcbb3481faef4ad449fb3 339 PIRSF PIRSF006470 4 336 5.7E-72 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS21415 19f99a1bcd9bcbb3481faef4ad449fb3 339 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 311 1.1E-71 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS21415 19f99a1bcd9bcbb3481faef4ad449fb3 339 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 39 292 3.9E-71 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS26540 756b6870f40318c80109574a65bddb93 301 SUPERFAMILY SSF103481 195 292 5.49E-7 T 29-03-2018 CVS48_RS26540 756b6870f40318c80109574a65bddb93 301 SUPERFAMILY SSF103481 51 145 8.5E-9 T 29-03-2018 CVS48_RS26540 756b6870f40318c80109574a65bddb93 301 Pfam PF00892 EamA-like transporter family 11 141 2.4E-8 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS26540 756b6870f40318c80109574a65bddb93 301 Pfam PF00892 EamA-like transporter family 164 288 1.8E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CVS48_RS21225 55b8dcf4ce1fc4dde358420f912a8840 220 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 160 1.2E-26 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS25640 44080086b3b468c4f938f58e856677c9 142 SUPERFAMILY SSF54593 8 136 2.97E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS25640 44080086b3b468c4f938f58e856677c9 142 Gene3D G3DSA:3.10.180.10 7 142 2.9E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS19835 839c9ae772cca8383147056c2ed1aa4a 430 PIRSF PIRSF005353 1 429 1.1E-175 T 29-03-2018 IPR026033 Purine permease PbuG-like CVS48_RS19835 839c9ae772cca8383147056c2ed1aa4a 430 Pfam PF00860 Permease family 17 390 2.3E-52 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CVS48_RS04885 62caa3769687e93bc3f8d07e2d9a28cf 251 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 42 226 8.8E-14 T 29-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CVS48_RS20115 766d306a5b1827f7d1ca779a59269c8c 282 Pfam PF02517 CAAX protease self-immunity 176 268 4.2E-21 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CVS48_RS12620 4e51d6769edf82f9d90cea2a07d98444 509 Pfam PF03929 PepSY-associated TM region 26 501 3.9E-16 T 29-03-2018 IPR005625 PepSY-associated TM protein CVS48_RS12420 315ea2ea0b2c1aa14fa45ea46a3e5fa1 71 Pfam PF04102 SlyX 8 71 1.0E-19 T 29-03-2018 IPR007236 SlyX CVS48_RS12420 315ea2ea0b2c1aa14fa45ea46a3e5fa1 71 Gene3D G3DSA:1.20.5.300 5 51 1.2E-14 T 29-03-2018 CVS48_RS27010 c40ea0a25280d3aa347a98c280fc40b1 265 Gene3D G3DSA:3.10.270.10 10 264 1.0E-99 T 29-03-2018 CVS48_RS27010 c40ea0a25280d3aa347a98c280fc40b1 265 Pfam PF02649 Type I GTP cyclohydrolase folE2 11 261 1.1E-87 T 29-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CVS48_RS27010 c40ea0a25280d3aa347a98c280fc40b1 265 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 11 265 35.306 T 29-03-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CVS48_RS00760 d855c479f53ce35f46744f9fac99925f 196 Gene3D G3DSA:1.10.530.10 24 191 2.9E-16 T 29-03-2018 CVS48_RS00760 d855c479f53ce35f46744f9fac99925f 196 SUPERFAMILY SSF53955 103 176 4.13E-16 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS00760 d855c479f53ce35f46744f9fac99925f 196 SUPERFAMILY SSF53955 33 75 4.13E-16 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS00760 d855c479f53ce35f46744f9fac99925f 196 Pfam PF01464 Transglycosylase SLT domain 36 157 1.6E-6 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CVS48_RS02030 c3ee380a718b5e000c256c5eff81a14a 232 Gene3D G3DSA:1.20.120.330 52 222 1.1E-7 T 29-03-2018 CVS48_RS20210 880116ed099894070c09e3e31d7742d4 489 Pfam PF00817 impB/mucB/samB family 28 145 8.3E-8 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CVS48_RS20210 880116ed099894070c09e3e31d7742d4 489 SUPERFAMILY SSF56672 2 226 3.34E-29 T 29-03-2018 CVS48_RS17065 773e9e75dae5b3e2140a4dd88a2f390d 138 Gene3D G3DSA:2.60.120.10 3 132 2.7E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CVS48_RS17065 773e9e75dae5b3e2140a4dd88a2f390d 138 Pfam PF07883 Cupin domain 49 116 1.7E-17 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CVS48_RS17065 773e9e75dae5b3e2140a4dd88a2f390d 138 SUPERFAMILY SSF51182 9 133 4.57E-29 T 29-03-2018 IPR011051 RmlC-like cupin domain CVS48_RS25970 2eb0b802414024ba8cfb696ac92d9732 182 Pfam PF01814 Hemerythrin HHE cation binding domain 18 157 3.1E-18 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CVS48_RS25970 2eb0b802414024ba8cfb696ac92d9732 182 Gene3D G3DSA:1.20.120.520 5 179 9.8E-31 T 29-03-2018 CVS48_RS01685 95d1c2df849cf919583853106f58eadc 157 Pfam PF00866 Ring hydroxylating beta subunit 18 149 1.7E-12 T 29-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CVS48_RS01685 95d1c2df849cf919583853106f58eadc 157 Gene3D G3DSA:3.10.450.50 6 156 6.7E-28 T 29-03-2018 CVS48_RS01685 95d1c2df849cf919583853106f58eadc 157 SUPERFAMILY SSF54427 2 157 1.08E-43 T 29-03-2018 IPR032710 NTF2-like domain CVS48_RS24125 c0d4b2c6f4febf2e7af539a5acf43545 432 Pfam PF09375 Imelysin 36 404 1.5E-100 T 29-03-2018 IPR018976 Peptidase M75, Imelysin CVS48_RS26565 6b757c3320962d9b5b06fab081e0366a 234 Pfam PF11254 Protein of unknown function (DUF3053) 12 225 3.4E-49 T 29-03-2018 IPR021413 Protein of unknown function DUF3053 CVS48_RS18910 76b0c1cc4131ca795dfefb354c6f11ba 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 267 4.3E-50 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CVS48_RS18910 76b0c1cc4131ca795dfefb354c6f11ba 268 Gene3D G3DSA:3.90.226.10 16 226 5.0E-63 T 29-03-2018 CVS48_RS18910 76b0c1cc4131ca795dfefb354c6f11ba 268 SUPERFAMILY SSF52096 14 267 1.46E-79 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CVS48_RS18910 76b0c1cc4131ca795dfefb354c6f11ba 268 Gene3D G3DSA:1.10.12.10 227 268 3.7E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal CVS48_RS16970 a071bc44f211caf73a39863200ecf4ca 204 Pfam PF03748 Flagellar basal body-associated protein FliL 104 204 2.2E-23 T 29-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CVS48_RS00665 541f71d3d950652bfaa8f2c1c078bda0 149 TIGRFAM TIGR03751 conj_TIGR03751: conjugative transfer region lipoprotein, TIGR03751 family 15 146 9.6E-53 T 29-03-2018 IPR022262 Lipoprotein, putative CVS48_RS23395 0eac074d6b360ef31954784b963d34f4 256 SUPERFAMILY SSF53335 12 234 5.55E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS23395 0eac074d6b360ef31954784b963d34f4 256 Gene3D G3DSA:3.40.50.150 45 248 1.4E-11 T 29-03-2018 CVS48_RS22840 14689dbb71012ad9ba232e997d85de06 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 284 4.0E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22840 14689dbb71012ad9ba232e997d85de06 288 SUPERFAMILY SSF161098 84 271 9.03E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS22840 14689dbb71012ad9ba232e997d85de06 288 Gene3D G3DSA:1.10.3720.10 11 276 7.9E-38 T 29-03-2018 CVS48_RS04430 810d4db15d44343f9f503e5401f5f955 143 Pfam PF10990 Protein of unknown function (DUF2809) 32 111 4.3E-18 T 29-03-2018 IPR021257 Protein of unknown function DUF2809 CVS48_RS19270 244755f0cc723a352d932ce71c300fa2 233 PIRSF PIRSF039137 1 233 7.0E-106 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CVS48_RS19270 244755f0cc723a352d932ce71c300fa2 233 Pfam PF00005 ABC transporter 17 161 1.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CVS48_RS19270 244755f0cc723a352d932ce71c300fa2 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CVS48_RS19270 244755f0cc723a352d932ce71c300fa2 233 SUPERFAMILY SSF52540 2 231 5.74E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS19270 244755f0cc723a352d932ce71c300fa2 233 SMART SM00382 26 212 2.2E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CVS48_RS19270 244755f0cc723a352d932ce71c300fa2 233 Gene3D G3DSA:3.40.50.300 1 233 5.0E-56 T 29-03-2018 CVS48_RS18835 924d8357dd193df5e24253461c8740c3 114 SUPERFAMILY SSF47413 13 63 1.32E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS18835 924d8357dd193df5e24253461c8740c3 114 Pfam PF13560 Helix-turn-helix domain 17 68 1.4E-6 T 29-03-2018 CVS48_RS18835 924d8357dd193df5e24253461c8740c3 114 SMART SM00530 21 76 0.0088 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS18835 924d8357dd193df5e24253461c8740c3 114 Gene3D G3DSA:1.10.260.40 6 73 4.8E-10 T 29-03-2018 CVS48_RS10435 8134a4462bd974b070e85963d98f7204 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 277 9.3E-38 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS10435 8134a4462bd974b070e85963d98f7204 295 Gene3D G3DSA:1.10.3470.10 1 284 2.1E-34 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS09305 b7a3fc92e43a6c6e7beb251331f68201 422 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 301 2.2E-27 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS09305 b7a3fc92e43a6c6e7beb251331f68201 422 Gene3D G3DSA:1.10.3470.10 18 312 1.5E-25 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS03880 3c616d1ba40d4ab837814a91a2ee89b3 314 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 31 227 1.1E-10 T 29-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CVS48_RS03880 3c616d1ba40d4ab837814a91a2ee89b3 314 SUPERFAMILY SSF53187 3 310 3.95E-53 T 29-03-2018 CVS48_RS03880 3c616d1ba40d4ab837814a91a2ee89b3 314 Gene3D G3DSA:3.40.630.10 26 262 5.9E-12 T 29-03-2018 CVS48_RS27040 729105de2c78fd4291a9e64005168027 336 Pfam PF01757 Acyltransferase family 9 327 5.5E-35 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CVS48_RS18215 47a987778da899541ca3a1559ed072e8 389 Gene3D G3DSA:1.10.3290.10 19 300 1.7E-39 T 29-03-2018 IPR003812 Fido domain CVS48_RS18215 47a987778da899541ca3a1559ed072e8 389 SUPERFAMILY SSF140931 99 284 4.32E-25 T 29-03-2018 IPR003812 Fido domain CVS48_RS18215 47a987778da899541ca3a1559ed072e8 389 Pfam PF02661 Fic/DOC family 125 215 1.4E-13 T 29-03-2018 IPR003812 Fido domain CVS48_RS12095 a4c245c511d2cd2770dad62ff2408b8e 134 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 34 107 2.2E-18 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CVS48_RS12095 a4c245c511d2cd2770dad62ff2408b8e 134 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 27 123 1.3E-34 T 29-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 CVS48_RS12095 a4c245c511d2cd2770dad62ff2408b8e 134 Gene3D G3DSA:1.20.1250.20 15 129 3.3E-4 T 29-03-2018 CVS48_RS03590 65fd4686cbbeafdea39100d1eec2f087 62 Pfam PF11943 Protein of unknown function (DUF3460) 4 60 2.6E-27 T 29-03-2018 IPR021853 Protein of unknown function DUF3460 CVS48_RS00620 2a1e6c4ab8a7b1da9902d3c96c92d0e7 121 Pfam PF12553 Protein of unknown function (DUF3742) 1 105 4.3E-42 T 29-03-2018 IPR022213 Protein of unknown function DUF3742 CVS48_RS11130 ce25d8956b3f021de67d0f0de33c0ceb 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 293 5.1E-37 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS11130 ce25d8956b3f021de67d0f0de33c0ceb 306 Gene3D G3DSA:1.10.3470.10 1 298 7.0E-44 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS20545 5af4a6125c1d7277a13f27e6dad21b85 216 Gene3D G3DSA:3.30.1330.60 40 215 5.2E-37 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS20545 5af4a6125c1d7277a13f27e6dad21b85 216 SUPERFAMILY SSF103088 70 201 2.09E-29 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS20545 5af4a6125c1d7277a13f27e6dad21b85 216 Pfam PF00691 OmpA family 92 196 1.1E-20 T 29-03-2018 IPR006665 OmpA-like domain CVS48_RS18875 4cebcfca7c25f952b8b6f6387b896feb 244 Pfam PF01564 Spermine/spermidine synthase domain 53 169 3.9E-12 T 29-03-2018 CVS48_RS18875 4cebcfca7c25f952b8b6f6387b896feb 244 SUPERFAMILY SSF53335 13 211 1.06E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS18875 4cebcfca7c25f952b8b6f6387b896feb 244 Gene3D G3DSA:3.40.50.150 2 236 3.6E-24 T 29-03-2018 CVS48_RS02615 c750db1bf35747e3d946017e03412836 154 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 145 1.4E-23 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 CVS48_RS26555 8825fb54be04481ede631fecb385134a 616 Pfam PF13687 Domain of unknown function (DUF4153) 169 399 4.2E-14 T 29-03-2018 IPR025291 Protein of unknown function DUF4153 CVS48_RS06295 bb7c4e925a8ef8cc67ecf10ba0e02cb8 426 SUPERFAMILY SSF56112 32 189 2.56E-13 T 29-03-2018 IPR011009 Protein kinase-like domain CVS48_RS06295 bb7c4e925a8ef8cc67ecf10ba0e02cb8 426 Gene3D G3DSA:1.10.510.10 26 348 1.4E-12 T 29-03-2018 CVS48_RS28660 e6e6055454cd3448611e0e4cd05c9e81 218 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 162 3.2E-33 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CVS48_RS03690 da090242b5a2c0f61784d11d6f99fe4c 328 Gene3D G3DSA:3.40.50.1980 51 170 4.0E-24 T 29-03-2018 CVS48_RS03690 da090242b5a2c0f61784d11d6f99fe4c 328 Pfam PF01497 Periplasmic binding protein 81 304 3.9E-20 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CVS48_RS03690 da090242b5a2c0f61784d11d6f99fe4c 328 SUPERFAMILY SSF53807 59 322 2.65E-56 T 29-03-2018 CVS48_RS03690 da090242b5a2c0f61784d11d6f99fe4c 328 Gene3D G3DSA:3.40.50.1980 171 328 8.2E-31 T 29-03-2018 CVS48_RS07235 337f60ab4a15d4f4a34548f6d7737c5a 101 Pfam PF11604 Copper binding periplasmic protein CusF 36 100 2.6E-24 T 29-03-2018 IPR021647 Copper binding periplasmic protein CusF CVS48_RS25605 8388cdb5fb3948f6b722602eee5056df 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 114 1.8E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CVS48_RS25605 8388cdb5fb3948f6b722602eee5056df 119 SUPERFAMILY SSF54593 2 118 8.19E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS25605 8388cdb5fb3948f6b722602eee5056df 119 Gene3D G3DSA:3.10.180.10 1 119 2.2E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS08315 54513e9948cdea155d9ac5595a31059d 206 Pfam PF11679 Protein of unknown function (DUF3275) 2 204 3.2E-47 T 29-03-2018 IPR021693 Protein of unknown function DUF3275 CVS48_RS08405 63ff023602bf28d349030e7be82519f4 322 Pfam PF03524 Conjugal transfer protein 53 297 1.4E-40 T 29-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX CVS48_RS04030 58d6c09da324afacbac10ca61c4cc9e4 301 Gene3D G3DSA:3.40.50.1820 1 301 3.5E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS04030 58d6c09da324afacbac10ca61c4cc9e4 301 SUPERFAMILY SSF53474 33 85 6.58E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS04030 58d6c09da324afacbac10ca61c4cc9e4 301 SUPERFAMILY SSF53474 113 271 6.58E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS21660 c5e119dcde6185155c632af399047837 220 Pfam PF13567 Domain of unknown function (DUF4131) 4 161 1.5E-18 T 29-03-2018 IPR025405 Domain of unknown function DUF4131 CVS48_RS07280 c0ba264989fab3338d61be68a54ce64e 227 Pfam PF06226 Protein of unknown function (DUF1007) 14 226 4.4E-54 T 29-03-2018 IPR010412 Protein of unknown function DUF1007 CVS48_RS24305 94183dc1635cdd4fb027180aba5b6dba 203 SUPERFAMILY SSF47240 10 82 1.25E-9 T 29-03-2018 IPR009078 Ferritin-like superfamily CVS48_RS24305 94183dc1635cdd4fb027180aba5b6dba 203 Gene3D G3DSA:1.20.1260.10 1 171 8.2E-23 T 29-03-2018 IPR012347 Ferritin-related CVS48_RS01075 4194529ece11218ae803ac8a442da4c6 160 Pfam PF01464 Transglycosylase SLT domain 23 133 3.0E-28 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CVS48_RS01075 4194529ece11218ae803ac8a442da4c6 160 SUPERFAMILY SSF53955 17 148 4.65E-34 T 29-03-2018 IPR023346 Lysozyme-like domain CVS48_RS01075 4194529ece11218ae803ac8a442da4c6 160 Gene3D G3DSA:1.10.530.10 14 150 1.3E-24 T 29-03-2018 CVS48_RS06625 88bc9c91dbac88417cf8ac769acd5147 127 Pfam PF13665 Domain of unknown function (DUF4150) 12 112 1.9E-30 T 29-03-2018 IPR025425 Domain of unknown function DUF4150 CVS48_RS00140 d37136a27ec6f4163f93d04546990361 551 Gene3D G3DSA:1.20.1250.20 15 232 6.4E-28 T 29-03-2018 CVS48_RS00140 d37136a27ec6f4163f93d04546990361 551 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CVS48_RS00140 d37136a27ec6f4163f93d04546990361 551 Pfam PF00083 Sugar (and other) transporter 449 545 5.0E-8 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS00140 d37136a27ec6f4163f93d04546990361 551 Pfam PF00083 Sugar (and other) transporter 26 336 9.8E-30 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CVS48_RS00140 d37136a27ec6f4163f93d04546990361 551 Gene3D G3DSA:1.20.1250.20 233 548 7.3E-31 T 29-03-2018 CVS48_RS00140 d37136a27ec6f4163f93d04546990361 551 SUPERFAMILY SSF103473 450 543 2.35E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS00140 d37136a27ec6f4163f93d04546990361 551 SUPERFAMILY SSF103473 21 346 2.35E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain CVS48_RS26240 a1fc6fa0f4f31b679ac5873cec8f8a73 269 Gene3D G3DSA:1.10.3720.10 7 269 6.1E-40 T 29-03-2018 CVS48_RS26240 a1fc6fa0f4f31b679ac5873cec8f8a73 269 SUPERFAMILY SSF161098 7 265 4.21E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS26240 a1fc6fa0f4f31b679ac5873cec8f8a73 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 261 2.7E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS14080 b4a3302c6bd7f2db74ef7c40981c1943 252 Pfam PF06912 Protein of unknown function (DUF1275) 22 238 2.3E-36 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 CVS48_RS09795 1884f82145391d65b0a79ccf805d3017 102 SUPERFAMILY SSF47413 35 91 3.38E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS13210 ca9977ed134be86878a1f1f7de18677e 374 Gene3D G3DSA:3.40.50.1110 49 374 8.1E-6 T 29-03-2018 CVS48_RS13210 ca9977ed134be86878a1f1f7de18677e 374 Pfam PF04914 DltD protein 65 176 6.3E-17 T 29-03-2018 IPR006998 DltD CVS48_RS13210 ca9977ed134be86878a1f1f7de18677e 374 Pfam PF04914 DltD protein 218 372 2.1E-27 T 29-03-2018 IPR006998 DltD CVS48_RS19285 03578b54d1a50479b20f90a8c8fc69e7 308 Gene3D G3DSA:1.10.3470.10 4 297 3.2E-52 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS19285 03578b54d1a50479b20f90a8c8fc69e7 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 292 9.5E-51 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS12720 d7b9b2c1845be848b80aa870dd6654a8 460 Gene3D G3DSA:3.40.720.10 119 419 0.0016 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS12720 d7b9b2c1845be848b80aa870dd6654a8 460 Pfam PF07394 Protein of unknown function (DUF1501) 47 404 4.4E-51 T 29-03-2018 IPR010869 Protein of unknown function DUF1501 CVS48_RS16955 bb1866404b0bc6e55e06a95ef12db76c 107 Pfam PF04347 Flagellar biosynthesis protein, FliO 25 105 8.0E-21 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CVS48_RS16955 bb1866404b0bc6e55e06a95ef12db76c 107 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 13 80 4.5E-22 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CVS48_RS09000 89ed3dd2d029a893255d0a5d26475d28 257 SUPERFAMILY SSF56317 1 252 9.55E-64 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS09000 89ed3dd2d029a893255d0a5d26475d28 257 Pfam PF00795 Carbon-nitrogen hydrolase 5 239 7.8E-41 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS09000 89ed3dd2d029a893255d0a5d26475d28 257 Gene3D G3DSA:3.60.110.10 2 256 9.0E-63 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CVS48_RS20585 6f9c3fcdbe9d08d6126e8d658344ae59 414 Gene3D G3DSA:1.10.357.10 217 406 1.1E-4 T 29-03-2018 CVS48_RS20585 6f9c3fcdbe9d08d6126e8d658344ae59 414 Pfam PF04286 Protein of unknown function (DUF445) 35 411 1.0E-102 T 29-03-2018 IPR007383 Protein of unknown function DUF445 CVS48_RS07465 3e68a089217fa707185994f733ac3112 395 Gene3D G3DSA:3.40.50.150 83 367 2.2E-11 T 29-03-2018 CVS48_RS07465 3e68a089217fa707185994f733ac3112 395 SUPERFAMILY SSF53335 25 387 1.38E-91 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CVS48_RS07465 3e68a089217fa707185994f733ac3112 395 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 91 323 1.1E-53 T 29-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 CVS48_RS27580 0e4cef54a45bea2216acf593a850aac0 325 Pfam PF14488 Domain of unknown function (DUF4434) 32 198 2.5E-30 T 29-03-2018 IPR027849 Protein of unknown function DUF4434 CVS48_RS27580 0e4cef54a45bea2216acf593a850aac0 325 Gene3D G3DSA:3.20.20.150 34 323 5.2E-4 T 29-03-2018 CVS48_RS07170 80938f900f9ba73742ba6042de99ec3c 376 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 159 373 4.2E-67 T 29-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria CVS48_RS07170 80938f900f9ba73742ba6042de99ec3c 376 Pfam PF02405 Permease MlaE 160 369 3.1E-67 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CVS48_RS16315 843c87a4554004f53b271d622ba9ac7a 223 Gene3D G3DSA:1.20.910.10 1 223 3.5E-35 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CVS48_RS16315 843c87a4554004f53b271d622ba9ac7a 223 Pfam PF14518 Iron-containing redox enzyme 39 206 1.9E-24 T 29-03-2018 IPR028201 PqqC-like protein CVS48_RS16315 843c87a4554004f53b271d622ba9ac7a 223 SUPERFAMILY SSF48613 1 214 3.76E-52 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CVS48_RS16315 843c87a4554004f53b271d622ba9ac7a 223 SMART SM01236 73 170 8.1E-5 T 29-03-2018 CVS48_RS18345 9f808b8a9d28fa0e4fe336c639a62ac2 310 SMART SM00945 70 184 1.0E-38 T 29-03-2018 IPR016103 ProQ/FinO domain CVS48_RS18345 9f808b8a9d28fa0e4fe336c639a62ac2 310 Gene3D G3DSA:1.10.1710.10 3 188 1.0E-40 T 29-03-2018 IPR016103 ProQ/FinO domain CVS48_RS18345 9f808b8a9d28fa0e4fe336c639a62ac2 310 Pfam PF04352 ProQ/FINO family 73 180 5.5E-32 T 29-03-2018 IPR016103 ProQ/FinO domain CVS48_RS18345 9f808b8a9d28fa0e4fe336c639a62ac2 310 SUPERFAMILY SSF48657 58 181 8.89E-32 T 29-03-2018 IPR016103 ProQ/FinO domain CVS48_RS02990 5b6dfc3c3730226f8ac345c0cc7c18bd 359 Gene3D G3DSA:3.30.420.40 1 173 1.2E-52 T 29-03-2018 CVS48_RS02990 5b6dfc3c3730226f8ac345c0cc7c18bd 359 Gene3D G3DSA:3.30.420.40 207 359 4.5E-25 T 29-03-2018 CVS48_RS02990 5b6dfc3c3730226f8ac345c0cc7c18bd 359 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 359 38.938 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CVS48_RS02990 5b6dfc3c3730226f8ac345c0cc7c18bd 359 SUPERFAMILY SSF53067 133 330 6.48E-26 T 29-03-2018 CVS48_RS02990 5b6dfc3c3730226f8ac345c0cc7c18bd 359 SUPERFAMILY SSF53067 58 103 6.48E-26 T 29-03-2018 CVS48_RS02990 5b6dfc3c3730226f8ac345c0cc7c18bd 359 SUPERFAMILY SSF53067 25 31 6.48E-26 T 29-03-2018 CVS48_RS02990 5b6dfc3c3730226f8ac345c0cc7c18bd 359 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 1 359 6.4E-138 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CVS48_RS07550 e003e3c8703f9769872cb12c08aa1cdb 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 295 3.8E-30 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CVS48_RS07550 e003e3c8703f9769872cb12c08aa1cdb 309 Gene3D G3DSA:1.10.3470.10 1 296 1.4E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CVS48_RS05760 a9cbb989bfdf263448ef7d6e1a45fd4e 306 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 1 284 2.3E-61 T 29-03-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 CVS48_RS13700 48b9b67bb6f5c82b482ac66fa921b704 92 Pfam PF04341 Protein of unknown function, DUF485 2 88 3.1E-22 T 29-03-2018 IPR007436 Protein of unknown function DUF485 CVS48_RS00030 5cff1658693dcd54395041fd69c00622 140 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 1 132 7.3E-22 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 CVS48_RS29085 5cff1658693dcd54395041fd69c00622 140 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 1 132 7.3E-22 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 CVS48_RS10070 dc88742a39bc70fdc79681588d0d6019 123 Pfam PF05656 Protein of unknown function (DUF805) 11 118 4.3E-28 T 29-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 CVS48_RS04705 463441e56fa0d9a55b95cd0417dadb4e 350 Gene3D G3DSA:1.10.533.10 132 212 5.1E-4 T 29-03-2018 CVS48_RS24340 b35e758b8cd22205a38e5bfb9e180293 204 Pfam PF06805 Bacteriophage lambda tail assembly protein I 8 89 2.3E-12 T 29-03-2018 IPR010654 Bacteriophage lambda tail assembly I CVS48_RS28765 2cb589be4f11a1d5fbf97087fb4d4129 486 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 18 468 8.0E-90 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CVS48_RS28765 2cb589be4f11a1d5fbf97087fb4d4129 486 Pfam PF02321 Outer membrane efflux protein 284 466 1.1E-19 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS28765 2cb589be4f11a1d5fbf97087fb4d4129 486 Pfam PF02321 Outer membrane efflux protein 68 257 8.2E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CVS48_RS28765 2cb589be4f11a1d5fbf97087fb4d4129 486 Gene3D G3DSA:1.20.1600.10 26 473 3.5E-91 T 29-03-2018 CVS48_RS28765 2cb589be4f11a1d5fbf97087fb4d4129 486 SUPERFAMILY SSF56954 4 472 9.02E-99 T 29-03-2018 CVS48_RS15450 76a644b542c1a8294fd91f047e0ace27 320 PIRSF PIRSF028561 3 320 2.5E-100 T 29-03-2018 IPR014548 Predicted acyltransferase CVS48_RS15450 76a644b542c1a8294fd91f047e0ace27 320 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 104 317 6.1E-9 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CVS48_RS17025 1d4270e07e7c4d535fc5100781bfe209 117 Pfam PF05400 Flagellar protein FliT 25 110 4.1E-18 T 29-03-2018 IPR008622 Flagellar protein FliT CVS48_RS17025 1d4270e07e7c4d535fc5100781bfe209 117 Gene3D G3DSA:1.20.58.380 12 96 1.1E-23 T 29-03-2018 CVS48_RS07180 977f9732ac1d2f2d192bf4db68f78cc8 310 Pfam PF02470 MlaD protein 34 103 3.0E-11 T 29-03-2018 IPR003399 Mce/MlaD CVS48_RS07180 977f9732ac1d2f2d192bf4db68f78cc8 310 Gene3D G3DSA:1.20.120.570 129 227 4.3E-4 T 29-03-2018 CVS48_RS02925 6c6a8e529f124d29b18fe7f3f1afc4e6 234 Pfam PF06551 Protein of unknown function (DUF1120) 30 135 1.0E-10 T 29-03-2018 IPR010546 Protein of unknown function DUF1120 CVS48_RS12990 ff33220ca1444782a5080c9b1e01b572 225 Gene3D G3DSA:3.10.180.10 3 147 5.7E-9 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CVS48_RS12990 ff33220ca1444782a5080c9b1e01b572 225 Pfam PF13468 Glyoxalase-like domain 5 189 1.4E-37 T 29-03-2018 IPR025870 Glyoxalase-like domain CVS48_RS28655 057a90ebfc4d1d5359a6d05e5b923619 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 102 21.039 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CVS48_RS28655 057a90ebfc4d1d5359a6d05e5b923619 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 98 6.9E-25 T 29-03-2018 CVS48_RS11865 d88cb2a949d0393cee63b43c7d6cb78f 329 Pfam PF13515 Fusaric acid resistance protein-like 3 118 7.7E-7 T 29-03-2018 CVS48_RS11240 591aabdb2fcf5144a2e4f9827d6ef825 529 Gene3D G3DSA:3.40.720.10 4 439 1.6E-83 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CVS48_RS11240 591aabdb2fcf5144a2e4f9827d6ef825 529 SUPERFAMILY SSF53649 153 514 6.15E-108 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS11240 591aabdb2fcf5144a2e4f9827d6ef825 529 SUPERFAMILY SSF53649 6 111 6.15E-108 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CVS48_RS11240 591aabdb2fcf5144a2e4f9827d6ef825 529 Pfam PF00884 Sulfatase 8 415 6.2E-54 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CVS48_RS11240 591aabdb2fcf5144a2e4f9827d6ef825 529 Gene3D G3DSA:3.30.1120.10 440 526 1.6E-7 T 29-03-2018 CVS48_RS22265 cb02374e42b7c9cb6dec638f4fc81fd5 321 Pfam PF06675 Protein of unknown function (DUF1177) 38 300 1.9E-114 T 29-03-2018 IPR009561 Protein of unknown function DUF1177 CVS48_RS16000 be4f317b7263ef80946cc2851f7740b9 409 Gene3D G3DSA:3.40.50.1110 43 351 9.7E-8 T 29-03-2018 CVS48_RS12525 5b5c985836666d52e6491de6635f5076 468 PIRSF PIRSF006060 8 464 1.5E-65 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CVS48_RS12525 5b5c985836666d52e6491de6635f5076 468 ProSitePatterns PS00218 Amino acid permeases signature. 50 80 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CVS48_RS12525 5b5c985836666d52e6491de6635f5076 468 Pfam PF00324 Amino acid permease 26 452 2.1E-95 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CVS48_RS02685 20cb5b5203f5ae99516fa78ad3717ea2 153 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 138 2.2E-26 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CVS48_RS04345 10d9505adc57fb86f15f8456788bf213 335 Pfam PF04116 Fatty acid hydroxylase superfamily 135 275 3.8E-31 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CVS48_RS17940 14626a4bf8ba6555a4e7fa87270b3995 154 SUPERFAMILY SSF143744 15 146 1.14E-34 T 29-03-2018 CVS48_RS17940 14626a4bf8ba6555a4e7fa87270b3995 154 Pfam PF03928 Haem-degrading 21 145 1.7E-28 T 29-03-2018 IPR005624 Haem-degrading CVS48_RS22775 93e50a9d59209210fd3f5452e87aaa2f 78 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 58 4.0E-17 T 29-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor CVS48_RS22775 93e50a9d59209210fd3f5452e87aaa2f 78 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 2 67 5.9E-31 T 29-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor CVS48_RS01695 7c5e834061897c0bc6f6b56552f33377 279 Pfam PF00899 ThiF family 25 276 6.0E-32 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CVS48_RS01695 7c5e834061897c0bc6f6b56552f33377 279 SUPERFAMILY SSF69572 241 276 1.57E-56 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CVS48_RS01695 7c5e834061897c0bc6f6b56552f33377 279 SUPERFAMILY SSF69572 14 201 1.57E-56 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CVS48_RS01695 7c5e834061897c0bc6f6b56552f33377 279 Gene3D G3DSA:3.40.50.720 8 279 2.7E-53 T 29-03-2018 CVS48_RS08500 293781350c2b4faea2a52bf72031026d 464 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 8 463 5.9E-100 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 CVS48_RS08500 293781350c2b4faea2a52bf72031026d 464 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 21 462 1.1E-106 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 CVS48_RS19380 f31ed653c4b162f470125c09d10c7ed8 368 Gene3D G3DSA:3.30.1890.10 26 337 2.0E-12 T 29-03-2018 CVS48_RS20510 410a37c3808c32cccd7fc7f3d6a35039 645 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 41 318 3.1E-33 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS20510 410a37c3808c32cccd7fc7f3d6a35039 645 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 428 635 5.4E-37 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS09745 842aed76bae83b64a634f6ae0af11d97 85 SMART SM00530 23 78 0.0038 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CVS48_RS09745 842aed76bae83b64a634f6ae0af11d97 85 Gene3D G3DSA:1.10.260.40 10 84 2.8E-8 T 29-03-2018 CVS48_RS09745 842aed76bae83b64a634f6ae0af11d97 85 SUPERFAMILY SSF47413 14 81 3.66E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CVS48_RS09745 842aed76bae83b64a634f6ae0af11d97 85 Pfam PF13560 Helix-turn-helix domain 19 76 2.5E-8 T 29-03-2018 CVS48_RS19790 e5123922a696b41330ebf040ff3c676f 101 Pfam PF15595 Immunity protein 51 2 99 4.2E-30 T 29-03-2018 IPR028956 Immunity protein 51 CVS48_RS26455 59e63a24bf03c094840da4e268bcf88c 203 SMART SM01144 2 187 1.3E-57 T 29-03-2018 IPR005636 DTW CVS48_RS26455 59e63a24bf03c094840da4e268bcf88c 203 Pfam PF03942 DTW domain 3 181 1.6E-39 T 29-03-2018 IPR005636 DTW CVS48_RS24640 0649ff569af03c49c31dc8802aab4b82 260 Gene3D G3DSA:2.10.230.10 51 111 1.0E-5 T 29-03-2018 CVS48_RS24640 0649ff569af03c49c31dc8802aab4b82 260 SUPERFAMILY SSF57938 64 104 2.88E-6 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CVS48_RS17840 4a8dc7a90e17c7edbb08766a44e39e7e 277 Pfam PF13827 Domain of unknown function (DUF4189) 165 255 9.5E-7 T 29-03-2018 IPR025240 Domain of unknown function DUF4189 CVS48_RS17840 4a8dc7a90e17c7edbb08766a44e39e7e 277 Pfam PF13827 Domain of unknown function (DUF4189) 34 127 4.4E-15 T 29-03-2018 IPR025240 Domain of unknown function DUF4189 CVS48_RS03445 1f5a50e44a06aba945fcd385c79f9338 125 Pfam PF09345 Domain of unknown function (DUF1987) 6 122 5.1E-39 T 29-03-2018 IPR018530 Domain of unknown function DUF1987 CVS48_RS14845 b1650b413898dcf5dd1b755ecfbd7692 289 Pfam PF00482 Type II secretion system (T2SS), protein F 152 276 3.2E-16 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS24815 50fe8940783327af84f98972c39afa27 669 Gene3D G3DSA:1.20.5.1230 17 545 1.2E-9 T 29-03-2018 CVS48_RS27565 392499d0d267abea9534bdb9c72b3166 719 Pfam PF03170 Bacterial cellulose synthase subunit 30 167 1.5E-5 T 29-03-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 CVS48_RS02255 e9742e33d71c69ae4b6fdcf17d9e9e26 691 Pfam PF05170 AsmA family 1 576 4.5E-127 T 29-03-2018 IPR007844 AsmA CVS48_RS10490 a4ffc23d66e4f210e4fa3d9581ff9730 168 Pfam PF03724 META domain 45 160 1.1E-18 T 29-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ CVS48_RS09460 8b949a3285c57a37209e408207b93646 371 Pfam PF01594 AI-2E family transporter 14 344 1.4E-37 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CVS48_RS13320 7de5b3483e42810caba29960cfa8e247 293 PIRSF PIRSF011468 4 293 6.2E-161 T 29-03-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS13320 7de5b3483e42810caba29960cfa8e247 293 Pfam PF06007 Phosphonate metabolism protein PhnJ 13 284 4.1E-147 T 29-03-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CVS48_RS26400 6246cb784f439e24177cefacd86acacc 167 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 8.2E-32 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CVS48_RS28805 debd53d04648129cd6d9a49d87eb1b84 378 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 128 351 4.7E-13 T 29-03-2018 IPR005079 Peptidase C45 CVS48_RS28805 debd53d04648129cd6d9a49d87eb1b84 378 Gene3D G3DSA:3.60.60.10 114 372 6.9E-25 T 29-03-2018 CVS48_RS07610 8409732d9315f0222ef6115c5dd64004 82 Gene3D G3DSA:3.40.1620.10 5 79 6.0E-4 T 29-03-2018 CVS48_RS03000 2c59f23fdfc037a070477ea885021916 234 Gene3D G3DSA:1.20.5.340 30 130 0.0014 T 29-03-2018 CVS48_RS04465 0daf676cffcd6a655f929a807c202bb4 466 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 20 442 2.2E-52 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CVS48_RS04465 0daf676cffcd6a655f929a807c202bb4 466 PIRSF PIRSF002744 2 465 4.1E-100 T 29-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CVS48_RS04965 8dbf8b73cee12fcd78bd361c054b59cf 74 Pfam PF11174 Protein of unknown function (DUF2970) 15 70 4.8E-25 T 29-03-2018 IPR021344 Protein of unknown function DUF2970 CVS48_RS21155 28da7628b0f6ca938e0bc1e8002e6b57 112 Gene3D G3DSA:3.30.1460.30 2 91 5.1E-5 T 29-03-2018 CVS48_RS08350 8110b2a1dce9d48b424868d6bb909bf4 150 Pfam PF07419 PilM 35 149 1.2E-21 T 29-03-2018 IPR009987 PilM, inner membrane CVS48_RS13740 39cd0bac73a9c8ce72b27b2fc9ceff87 419 SUPERFAMILY SSF89796 2 414 6.02E-124 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS13740 39cd0bac73a9c8ce72b27b2fc9ceff87 419 Pfam PF02515 CoA-transferase family III 4 391 1.4E-115 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CVS48_RS13740 39cd0bac73a9c8ce72b27b2fc9ceff87 419 Gene3D G3DSA:3.40.50.10540 1 419 1.7E-134 T 29-03-2018 IPR023606 CoA-transferase family III domain CVS48_RS07350 01e97788564d275d6241b907934b68c2 297 Gene3D G3DSA:3.20.20.370 8 295 1.8E-43 T 29-03-2018 CVS48_RS07350 01e97788564d275d6241b907934b68c2 297 Pfam PF01522 Polysaccharide deacetylase 67 173 1.3E-6 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CVS48_RS07350 01e97788564d275d6241b907934b68c2 297 SUPERFAMILY SSF88713 4 287 1.04E-58 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CVS48_RS08185 8d689ed2fb12c629c87779007791393f 386 Pfam PF03824 High-affinity nickel-transport protein 15 144 8.6E-16 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CVS48_RS08185 8d689ed2fb12c629c87779007791393f 386 Pfam PF03824 High-affinity nickel-transport protein 242 384 1.3E-19 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CVS48_RS17520 f79deaca118b5592f199b56cdce81a7f 104 SUPERFAMILY SSF48295 3 70 3.87E-16 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CVS48_RS17520 f79deaca118b5592f199b56cdce81a7f 104 Pfam PF06627 Protein of unknown function (DUF1153) 7 62 4.2E-8 T 29-03-2018 IPR009534 Protein of unknown function DUF1153 CVS48_RS17520 f79deaca118b5592f199b56cdce81a7f 104 Gene3D G3DSA:1.10.10.10 3 81 2.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24375 52352609c21b5beeb153d188ad81afe6 120 Pfam PF08809 Phage related hypothetical protein (DUF1799) 42 114 2.3E-9 T 29-03-2018 IPR014915 Bacteriophage TLS, TfmB CVS48_RS25735 d019d53e56e293f503fa8abb6a9580b6 77 Gene3D G3DSA:1.10.10.620 1 61 4.1E-12 T 29-03-2018 CVS48_RS22225 100c048699090eb9073c92f964e5aaff 402 Pfam PF00487 Fatty acid desaturase 17 230 2.0E-11 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CVS48_RS22225 100c048699090eb9073c92f964e5aaff 402 Pfam PF01610 Transposase 276 401 2.2E-8 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CVS48_RS26270 02a40f5698e583cf1c9ef29ae6be96eb 845 Pfam PF02687 FtsX-like permease family 302 381 1.4E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CVS48_RS26270 02a40f5698e583cf1c9ef29ae6be96eb 845 Pfam PF02687 FtsX-like permease family 749 838 1.0E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CVS48_RS11345 9f8e082786cbce5faf8e52d88fff5bae 307 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 11 266 2.2E-23 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CVS48_RS11345 9f8e082786cbce5faf8e52d88fff5bae 307 SUPERFAMILY SSF53213 9 290 1.57E-27 T 29-03-2018 CVS48_RS11345 9f8e082786cbce5faf8e52d88fff5bae 307 Gene3D G3DSA:3.40.830.10 2 305 2.4E-39 T 29-03-2018 CVS48_RS03850 0899be9072b756910d48ddf65369d16a 298 Pfam PF03547 Membrane transport protein 151 291 2.2E-14 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CVS48_RS06440 14d5fb97194235bd928618b5a24cfcc6 146 Gene3D G3DSA:1.20.1170.10 23 146 4.1E-7 T 29-03-2018 CVS48_RS02650 77e8c5787848fa7069f4fad99ec51ddd 142 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 2 137 2.7E-20 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 CVS48_RS27305 164f9525f8a350aa3b9ece424f10cebf 94 PIRSF PIRSF030200 1 94 2.9E-42 T 29-03-2018 IPR009359 Phenylacetic acid degradation B CVS48_RS27305 164f9525f8a350aa3b9ece424f10cebf 94 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 5 94 2.9E-42 T 29-03-2018 IPR009359 Phenylacetic acid degradation B CVS48_RS27305 164f9525f8a350aa3b9ece424f10cebf 94 Pfam PF06243 Phenylacetic acid degradation B 4 90 1.2E-38 T 29-03-2018 IPR009359 Phenylacetic acid degradation B CVS48_RS28950 47ca7c924e5818ed3d8827c6ff88ce22 294 Pfam PF07007 Lysozyme inhibitor LprI 46 105 1.2E-8 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal CVS48_RS10675 9fce9a0ea81d228f01c05741fc7ac8c8 368 Pfam PF00953 Glycosyl transferase family 4 75 230 5.0E-28 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CVS48_RS17415 9d4e661beeb7fdd6cc083789c91308c7 135 Pfam PF07681 DoxX 9 89 4.1E-20 T 29-03-2018 IPR032808 DoxX family CVS48_RS04340 578fb578f4bcdb2679de745bc816560e 166 SUPERFAMILY SSF54637 8 156 4.36E-44 T 29-03-2018 IPR029069 HotDog domain CVS48_RS04340 578fb578f4bcdb2679de745bc816560e 166 Gene3D G3DSA:3.10.129.10 2 154 7.4E-47 T 29-03-2018 CVS48_RS04340 578fb578f4bcdb2679de745bc816560e 166 Pfam PF03061 Thioesterase superfamily 24 97 2.8E-17 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CVS48_RS08190 64019fa754800e4cd95ec58c4a1beefc 92 Pfam PF02583 Metal-sensitive transcriptional repressor 10 89 1.8E-22 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CVS48_RS22780 eaae4eea37ddb3624c2fd8903dd15bd7 141 Pfam PF04170 NlpE N-terminal domain 46 129 3.7E-25 T 29-03-2018 IPR007298 Copper resistance lipoprotein NlpE CVS48_RS06940 2078f483cb3848fc0c6568e0ea284bf9 223 Pfam PF04367 Protein of unknown function (DUF502) 58 163 3.7E-37 T 29-03-2018 IPR007462 Protein of unknown function DUF502 CVS48_RS21245 c008ea7256158cf641250aa62db2d5fc 271 Pfam PF06966 Protein of unknown function (DUF1295) 22 248 3.8E-71 T 29-03-2018 IPR010721 Protein of unknown function DUF1295 CVS48_RS12130 c05d0348403642b0933752b45f2a74f7 427 Gene3D G3DSA:2.130.10.130 16 379 3.1E-4 T 29-03-2018 CVS48_RS21650 0baad3c9f26a58759e295024feb6b4c1 362 Gene3D G3DSA:3.40.1350.10 30 169 1.9E-9 T 29-03-2018 CVS48_RS27640 91810ce92203dbfdb5476065e6650d01 110 Pfam PF04972 BON domain 39 106 6.3E-20 T 29-03-2018 IPR007055 BON domain CVS48_RS27640 91810ce92203dbfdb5476065e6650d01 110 SMART SM00749 44 107 2.3E-6 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria CVS48_RS02270 76a0352d404af47fa8ddf2d8385e7eed 153 Pfam PF03692 Putative zinc- or iron-chelating domain 26 109 2.2E-9 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein CVS48_RS16420 6c3529e7a8338e7a3b9768e7db64b72b 559 SUPERFAMILY SSF52540 53 205 1.52E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CVS48_RS16420 6c3529e7a8338e7a3b9768e7db64b72b 559 Gene3D G3DSA:3.40.50.300 28 389 7.5E-9 T 29-03-2018 CVS48_RS23590 528d4c00bb22b32ae226391408655a2a 307 Gene3D G3DSA:3.40.50.1820 115 265 0.0056 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS23590 528d4c00bb22b32ae226391408655a2a 307 Pfam PF00482 Type II secretion system (T2SS), protein F 140 266 9.2E-12 T 29-03-2018 IPR018076 Type II secretion system F domain CVS48_RS02325 8bf32b1ccdfaa771f4ec343db80272a7 217 SUPERFAMILY SSF161098 8 207 2.75E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS02325 8bf32b1ccdfaa771f4ec343db80272a7 217 Gene3D G3DSA:1.10.3720.10 1 217 1.1E-40 T 29-03-2018 CVS48_RS02325 8bf32b1ccdfaa771f4ec343db80272a7 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 215 2.9E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS19600 5c024436f9b2f2dc7fbddac55197b78f 344 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 106 330 1.0E-47 T 29-03-2018 IPR005079 Peptidase C45 CVS48_RS19600 5c024436f9b2f2dc7fbddac55197b78f 344 Gene3D G3DSA:3.60.60.10 95 342 1.4E-19 T 29-03-2018 CVS48_RS25135 2da86a58d121ed61ff09cc993e46d831 343 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 43 321 1.9E-88 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CVS48_RS25135 2da86a58d121ed61ff09cc993e46d831 343 PIRSF PIRSF006470 6 338 3.6E-112 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS25135 2da86a58d121ed61ff09cc993e46d831 343 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 40 294 3.5E-83 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CVS48_RS08380 0eaf18080f68515286504b183c154374 171 TIGRFAM TIGR03021 pilP_fam: type IV pilus biogenesis protein PilP 71 131 7.1E-13 T 29-03-2018 IPR022753 Type IV pilus biogenesis PilP CVS48_RS26600 d9d354afbd21e0d27171b19f1c05aa52 273 Pfam PF01925 Sulfite exporter TauE/SafE 10 262 5.9E-55 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CVS48_RS23625 37308bcad496bcedc7dacaaec0dd4920 168 Pfam PF01478 Type IV leader peptidase family 5 114 3.5E-12 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CVS48_RS17630 22e840ece20f071c5d216ea5dfea368d 116 Pfam PF11804 Protein of unknown function (DUF3325) 11 108 3.4E-31 T 29-03-2018 IPR021762 Protein of unknown function DUF3325 CVS48_RS10530 42b0784f14ba3bd077528cc4c4208960 1281 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 941 1276 1.4E-33 T 29-03-2018 IPR007452 Translocation and assembly module TamB CVS48_RS27730 d7565e991d41f3ee0881b9ce99e86922 102 Pfam PF12365 Protein of unknown function (DUF3649) 69 94 8.2E-11 T 29-03-2018 IPR022109 Protein of unknown function DUF3649 CVS48_RS01385 3d0efcf4aea6d5871800d6e12711830f 335 Pfam PF01699 Sodium/calcium exchanger protein 195 328 1.7E-9 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CVS48_RS01385 3d0efcf4aea6d5871800d6e12711830f 335 Pfam PF01699 Sodium/calcium exchanger protein 5 158 4.3E-14 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CVS48_RS21490 d75343422a92e54870d06bd4693f7497 325 Pfam PF14022 Protein of unknown function (DUF4238) 6 275 1.2E-31 T 29-03-2018 IPR025332 Protein of unknown function DUF4238 CVS48_RS14420 17a3ebac7a2e0e7bd11345aa46eeddf0 183 Pfam PF07291 Methylamine utilisation protein MauE 1 173 1.5E-19 T 29-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 CVS48_RS04845 3bb49b7bb29c5d72c5fe23f63ad7b798 854 Gene3D G3DSA:3.90.320.10 594 765 0.001 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CVS48_RS22390 764b7ef0c7988c4b9ff441a1d7812d65 554 Pfam PF02470 MlaD protein 53 141 2.4E-11 T 29-03-2018 IPR003399 Mce/MlaD CVS48_RS22390 764b7ef0c7988c4b9ff441a1d7812d65 554 Pfam PF02470 MlaD protein 173 232 2.3E-7 T 29-03-2018 IPR003399 Mce/MlaD CVS48_RS22390 764b7ef0c7988c4b9ff441a1d7812d65 554 Pfam PF02470 MlaD protein 303 408 5.6E-13 T 29-03-2018 IPR003399 Mce/MlaD CVS48_RS22390 764b7ef0c7988c4b9ff441a1d7812d65 554 Gene3D G3DSA:3.90.20.10 388 534 2.7E-4 T 29-03-2018 CVS48_RS17230 278131932347623d185e32fc96adf2d3 145 Gene3D G3DSA:2.40.50.140 64 144 5.1E-4 T 29-03-2018 CVS48_RS16695 af17eb6bab72b5fa064c2bbe3cdc22b6 63 Pfam PF14070 Putative motility protein 10 61 2.5E-10 T 29-03-2018 IPR025906 Putative motility protein CVS48_RS09840 9fbb643edc713fbb62cb035a0f91c30a 249 Pfam PF01578 Cytochrome C assembly protein 29 245 5.5E-25 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CVS48_RS21220 78af370301915cc80e3b574d9a6b2c1e 553 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 513 1.3E-116 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CVS48_RS18765 8d41a9148c9cbeabb31cf776caf7a467 301 Pfam PF04972 BON domain 216 282 3.9E-14 T 29-03-2018 IPR007055 BON domain CVS48_RS01330 f8e11d78fca98618dd08b4fedddf8ee7 111 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 11 107 1.2E-21 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CVS48_RS16495 2a571fccd36e2bcf97dd6ce329a2522d 306 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 36 270 2.2E-30 T 29-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CVS48_RS25765 3275e82eb0446ce2363c40faa67f8a54 312 Pfam PF10002 Predicted membrane protein (DUF2243) 19 160 7.8E-39 T 29-03-2018 IPR018719 Protein of unknown function DUF2243, membrane CVS48_RS23570 7a1415e53e4b80240810ab4370161a83 698 Pfam PF09977 Putative Tad-like Flp pilus-assembly 61 156 4.8E-6 T 29-03-2018 IPR018705 Domain of unknown function DUF2134, membrane CVS48_RS06745 ad8f5f5f581a8fa29ff482fc42aa82aa 58 Pfam PF13627 Prokaryotic lipoprotein-attachment site 17 35 8.6E-8 T 29-03-2018 IPR032831 Prokaryotic lipoprotein-attachment site CVS48_RS08175 ef12c08a715964c70a2bf92358952a96 243 Gene3D G3DSA:1.20.1170.10 74 243 4.7E-5 T 29-03-2018 CVS48_RS18965 15e2c94addf97315ba4334c854ad14f4 264 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 73 226 1.9E-35 T 29-03-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 CVS48_RS23635 fcae8457d58621031a565fa45ca077d3 276 Pfam PF03707 Bacterial signalling protein N terminal repeat 60 117 1.4E-15 T 29-03-2018 IPR005330 MHYT domain CVS48_RS23635 fcae8457d58621031a565fa45ca077d3 276 Pfam PF03707 Bacterial signalling protein N terminal repeat 123 177 4.6E-16 T 29-03-2018 IPR005330 MHYT domain CVS48_RS24425 8d9eee1ccfc6620129a95ddb6b19ac64 68 Gene3D G3DSA:3.30.1580.10 16 59 3.6E-6 T 29-03-2018 CVS48_RS08355 29ca570619c2263571bd7a69dcc6968c 413 Pfam PF04917 Bacterial shufflon protein, N-terminal constant region 245 341 5.4E-12 T 29-03-2018 IPR007001 Bacterial shufflon protein, N-terminal CVS48_RS08355 29ca570619c2263571bd7a69dcc6968c 413 Pfam PF04917 Bacterial shufflon protein, N-terminal constant region 42 248 1.0E-36 T 29-03-2018 IPR007001 Bacterial shufflon protein, N-terminal CVS48_RS06915 7f3034abe0a9d7b78d5dc73b185ad752 302 Pfam PF00487 Fatty acid desaturase 42 261 3.2E-24 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CVS48_RS20515 8a8fc020afeb3d3f8181bdff45835a38 208 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 159 8.3E-25 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS17600 744f7f68831c8290e044e8e7ec94535f 462 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 17 440 2.4E-38 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CVS48_RS06685 e13d2879fdfc5e8470643fa6c8786812 218 Pfam PF12059 Protein of unknown function (DUF3540) 23 218 9.1E-60 T 29-03-2018 IPR021927 Protein of unknown function DUF3540 CVS48_RS08855 4502f88fb05d6ccd7244d60993c77081 293 SUPERFAMILY SSF161098 11 286 7.06E-59 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS08855 4502f88fb05d6ccd7244d60993c77081 293 Gene3D G3DSA:1.10.3720.10 17 291 4.8E-48 T 29-03-2018 CVS48_RS08855 4502f88fb05d6ccd7244d60993c77081 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 282 3.2E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CVS48_RS01050 4a40850114d0ecec2608a4e01fc34647 190 Gene3D G3DSA:3.30.70.60 103 189 1.6E-4 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CVS48_RS18435 503267b71fa08c8c00b546d245af7ea6 254 Gene3D G3DSA:3.60.10.10 4 253 2.1E-32 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS18435 503267b71fa08c8c00b546d245af7ea6 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 34 245 2.0E-17 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS18435 503267b71fa08c8c00b546d245af7ea6 254 SUPERFAMILY SSF56219 11 252 2.62E-50 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CVS48_RS17635 12b6490ca48191fbb8238907bd32126e 536 Pfam PF03929 PepSY-associated TM region 2 377 4.8E-60 T 29-03-2018 IPR005625 PepSY-associated TM protein CVS48_RS26405 a5bef57ec0e0ba1273e29e6f83883693 315 Pfam PF01618 MotA/TolQ/ExbB proton channel family 156 274 4.2E-34 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CVS48_RS02755 7da0b079fc1a836d1e9cdbfc811f57f6 214 Pfam PF01810 LysE type translocator 30 203 5.1E-17 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CVS48_RS02435 07dc1432214088d08e002595f54b7211 135 Pfam PF05258 Protein of unknown function (DUF721) 8 70 3.7E-6 T 29-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 CVS48_RS23290 b36416d86973311e9f13733c2b86659f 187 Pfam PF13590 Domain of unknown function (DUF4136) 17 171 1.1E-34 T 29-03-2018 IPR025411 Domain of unknown function DUF4136 CVS48_RS10945 1678d1901e03cd89aef85d521f822011 832 Pfam PF05170 AsmA family 1 207 4.3E-28 T 29-03-2018 IPR007844 AsmA CVS48_RS10945 1678d1901e03cd89aef85d521f822011 832 Pfam PF05170 AsmA family 472 720 2.9E-33 T 29-03-2018 IPR007844 AsmA CVS48_RS28935 35949f50573b2b7d632058cec22434c4 449 Pfam PF05488 PAAR motif 9 76 9.0E-18 T 29-03-2018 IPR008727 PAAR motif CVS48_RS04125 d89cf250e34e556d7db5f38e6eb59f2b 141 Pfam PF03899 ATP synthase I chain 32 125 1.6E-9 T 29-03-2018 IPR005598 ATP synthase protein I CVS48_RS17785 3f0a3bb7b923a36f1a0322a1d52cd581 322 Gene3D G3DSA:2.40.128.130 22 164 4.1E-4 T 29-03-2018 CVS48_RS17785 3f0a3bb7b923a36f1a0322a1d52cd581 322 Gene3D G3DSA:2.40.128.130 165 322 0.016 T 29-03-2018 CVS48_RS21615 cec36d8fc53aa76c9ccb3b0f6edb52a6 381 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 279 350 7.8E-13 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family CVS48_RS11340 5712085077fb48a4fb742c288b59e4ad 183 Pfam PF01047 MarR family 64 120 5.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS11340 5712085077fb48a4fb742c288b59e4ad 183 SMART SM00347 56 156 1.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CVS48_RS11340 5712085077fb48a4fb742c288b59e4ad 183 Gene3D G3DSA:1.10.10.10 3 176 1.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS11340 5712085077fb48a4fb742c288b59e4ad 183 SUPERFAMILY SSF46785 34 168 2.83E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CVS48_RS24830 228b7d45bda3e8b063a57de3cda94d6a 452 Pfam PF11863 Protein of unknown function (DUF3383) 4 446 3.7E-69 T 29-03-2018 IPR021808 Protein of unknown function DUF3383 CVS48_RS17545 3c68cecdc2c4b0401fa7c4964d19d012 103 TIGRFAM TIGR02953 penta_MxKDx: pentapeptide MXKDX repeat protein 4 76 1.1E-20 T 29-03-2018 IPR014299 Pentapeptide MXKDX repeat protein CVS48_RS17545 3c68cecdc2c4b0401fa7c4964d19d012 103 TIGRFAM TIGR02953 penta_MxKDx: pentapeptide MXKDX repeat protein 52 103 4.6E-14 T 29-03-2018 IPR014299 Pentapeptide MXKDX repeat protein CVS48_RS12480 c9d3a9bd2c520fdc2c650dbf71ecb6f7 142 Pfam PF11162 Protein of unknown function (DUF2946) 21 139 2.1E-9 T 29-03-2018 IPR021333 Protein of unknown function DUF2946 CVS48_RS10335 6358b56dfa62777460037be73441a10f 229 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 208 1.1E-25 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CVS48_RS04605 ad51c4d4483f691483f1c0e60c798256 297 Pfam PF14080 Domain of unknown function (DUF4261) 207 283 1.1E-14 T 29-03-2018 IPR025357 Domain of unknown function DUF4261 CVS48_RS26475 9fddb3acb19fe3763fce546766f4f54f 314 Pfam PF03547 Membrane transport protein 159 304 8.6E-18 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CVS48_RS26475 9fddb3acb19fe3763fce546766f4f54f 314 Pfam PF03547 Membrane transport protein 4 145 1.8E-15 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CVS48_RS26335 c4f74e1656c08a8b50fa23cb7d6a6bb3 96 Pfam PF12112 Protein of unknown function (DUF3579) 5 93 1.5E-37 T 29-03-2018 IPR021969 Protein of unknown function DUF3579 CVS48_RS05885 0e80d2203ec12352e415c1de94f86693 592 Pfam PF02538 Hydantoinase B/oxoprolinase 25 549 2.3E-170 T 29-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 CVS48_RS02155 9c38d718f46f42888fdcd18c686906af 259 Pfam PF11745 Protein of unknown function (DUF3304) 15 135 1.0E-12 T 29-03-2018 IPR021733 Protein of unknown function DUF3304 CVS48_RS26135 cbc6eecda79423c56f2a5bb84c71c40b 95 Pfam PF03692 Putative zinc- or iron-chelating domain 11 65 7.4E-5 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein CVS48_RS09685 40b8ac978c3a70549c8393a2dfe0b021 426 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 9 86 0.001 T 29-03-2018 CVS48_RS20945 0d90b735fa725be54041b99a4ed0ea24 473 Gene3D G3DSA:3.40.50.1820 178 456 9.2E-4 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CVS48_RS07115 3d96b4c61e39cd444fcc65eba5d4df93 197 Pfam PF02397 Bacterial sugar transferase 3 196 3.3E-57 T 29-03-2018 IPR003362 Bacterial sugar transferase CVS48_RS15050 2f76eccb71ed45ed4fef7f261dcadb7d 180 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 36 164 3.2E-26 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CVS48_RS24570 893d0eca53ea534ed431f590f0182a3f 147 Pfam PF06892 Phage regulatory protein CII (CP76) 25 142 4.1E-6 T 29-03-2018 IPR009679 Bacteriophage 186, CII CVS48_RS17680 edbffa2c29fff9f3e77aa21a4e25a865 313 Gene3D G3DSA:1.20.58.60 3 310 7.0E-4 T 29-03-2018 CVS48_RS05355 41d9b1c2baaa27e4430b766d51c2bda9 490 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 475 1.4E-108 T 29-03-2018 IPR010352 Protein of unknown function DUF945 CVS48_RS20095 8d627aa72f7a6c7e58c899df34368a50 653 Pfam PF13515 Fusaric acid resistance protein-like 350 471 3.1E-13 T 29-03-2018 CVS48_RS15670 84532902f0e4bad2c24a782d61607543 146 Pfam PF06250 Protein of unknown function (DUF1016) 1 122 6.4E-35 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 CVS48_RS00345 2ba864a3814497ff6584cbd126b1ae6c 418 Pfam PF04932 O-Antigen ligase 184 338 1.1E-21 T 29-03-2018 IPR007016 O-antigen ligase-related CVS48_RS26225 3e670c66f0b4ff7880b584c99fe1e98c 233 Pfam PF10707 PhoP regulatory network protein YrbL 22 223 3.8E-73 T 29-03-2018 IPR019647 PhoP regulatory network protein YrbL CVS48_RS24260 7badb2b4d98774a8f94ec0e52c8ceeeb 242 SUPERFAMILY SSF56024 104 201 1.83E-5 T 29-03-2018