locus-tag	class	description
CLM73_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLM73_RS00010	COG0592	DNA-directed DNA polymerase activity
CLM73_RS00020	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS00055	COG0583	DNA-binding transcription factor activity
CLM73_RS00060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS00065	COG0765	amino acid transport
CLM73_RS00070	COG0765	amino acid transport
CLM73_RS00075	COG1126	abc transporter atp-binding protein
CLM73_RS00100	COG1304	FMN binding
CLM73_RS00110	COG3842	ATPase activity
CLM73_RS00115	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLM73_RS00120	COG1177	transmembrane transport
CLM73_RS00150	COG1609	Transcriptional regulator
CLM73_RS00160	COG3842	ATPase activity
CLM73_RS00165	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLM73_RS00170	COG1177	transmembrane transport
CLM73_RS00195	COG0251	oxidation-reduction process
CLM73_RS00200	COG0402	S-adenosylhomocysteine deaminase activity
CLM73_RS00205	COG1079	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS00210	COG4603	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS00215	COG3845	ABC transporter
CLM73_RS00220	COG1744	ABC transporter substrate-binding protein PnrA-like
CLM73_RS00230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLM73_RS00245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLM73_RS00270	COG3781	membrane
CLM73_RS00275	COG1522	sequence-specific DNA binding
CLM73_RS00280	COG0028	Belongs to the TPP enzyme family
CLM73_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS00290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS00295	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CLM73_RS00305	COG0551	DNA topoisomerase type I activity
CLM73_RS00305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLM73_RS00315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLM73_RS00320	COG2922	Belongs to the Smg family
CLM73_RS00330	COG2358	TRAP transporter, solute receptor (TAXI family
CLM73_RS00355	COG0765	amino acid transport
CLM73_RS00360	COG0765	amino acid transport
CLM73_RS00365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS00370	COG0583	DNA-binding transcription factor activity
CLM73_RS00385	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS00390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLM73_RS00445	COG1595	DNA-templated transcription, initiation
CLM73_RS00450	COG0753	catalase activity
CLM73_RS00460	COG2186	Transcriptional regulator
CLM73_RS00465	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS00515	COG0477	Major facilitator Superfamily
CLM73_RS00525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLM73_RS00530	COG0183	Belongs to the thiolase family
CLM73_RS00535	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CLM73_RS00540	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS00545	COG1473	amidohydrolase
CLM73_RS00550	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS00555	COG1742	UPF0060 membrane protein
CLM73_RS00565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM73_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLM73_RS00620	COG0395	ABC-type sugar transport system, permease component
CLM73_RS00625	COG1175	transmembrane transport
CLM73_RS00630	COG1653	transport
CLM73_RS00640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLM73_RS00645	COG1609	Transcriptional regulator
CLM73_RS00650	COG0154	amidase activity
CLM73_RS00655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLM73_RS00665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CLM73_RS00695	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CLM73_RS00700	COG1280	lysine exporter protein (LysE YggA)
CLM73_RS00705	COG0513	Belongs to the DEAD box helicase family
CLM73_RS00710	COG5339	Protein conserved in bacteria
CLM73_RS00730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS00735	COG0601	transmembrane transport
CLM73_RS00740	COG4166	transmembrane transport
CLM73_RS00745	COG1160	GTP binding
CLM73_RS00755	COG3708	Transcriptional regulator
CLM73_RS00755	COG2207	Transcriptional regulator
CLM73_RS00760	COG0697	spore germination
CLM73_RS00765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLM73_RS00775	COG0583	DNA-binding transcription factor activity
CLM73_RS00805	COG2969	positive regulation of protein catabolic process
CLM73_RS00810	COG0625	glutathione transferase activity
CLM73_RS00815	COG2857	Cytochrome c1
CLM73_RS00820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CLM73_RS00825	COG0723	plastoquinol--plastocyanin reductase activity
CLM73_RS00830	COG1970	mechanosensitive ion channel activity
CLM73_RS00835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLM73_RS00840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLM73_RS00855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLM73_RS00860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLM73_RS00865	COG0537	adenosine 5'-monophosphoramidase activity
CLM73_RS00870	COG0140	phosphoribosyl-ATP diphosphatase activity
CLM73_RS00880	COG0107	imidazoleglycerol-phosphate synthase activity
CLM73_RS00885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLM73_RS00890	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLM73_RS00895	COG0131	Imidazoleglycerol-phosphate dehydratase
CLM73_RS00900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLM73_RS00905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLM73_RS00910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CLM73_RS00915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLM73_RS00925	COG0842	Transport permease protein
CLM73_RS00930	COG1131	(ABC) transporter
CLM73_RS00940	COG2853	Lipoprotein
CLM73_RS00945	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLM73_RS00950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLM73_RS00955	COG1127	ABC transporter
CLM73_RS00960	COG2070	2-Nitropropane dioxygenase
CLM73_RS00975	COG0583	DNA-binding transcription factor activity
CLM73_RS00980	COG3047	cAMP biosynthetic process
CLM73_RS00990	COG0067	glutamate synthase
CLM73_RS00990	COG0069	glutamate synthase activity
CLM73_RS00990	COG0070	glutamate synthase
CLM73_RS01015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLM73_RS01035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLM73_RS01065	COG1612	heme a metabolic process
CLM73_RS01075	COG1999	signal sequence binding
CLM73_RS01095	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLM73_RS01100	COG2814	Major facilitator Superfamily
CLM73_RS01115	COG1522	sequence-specific DNA binding
CLM73_RS01150	COG1024	Enoyl-CoA hydratase
CLM73_RS01155	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS01160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLM73_RS01170	COG1024	Enoyl-CoA hydratase
CLM73_RS01175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS01185	COG2070	2-Nitropropane dioxygenase
CLM73_RS01210	COG2814	Major facilitator Superfamily
CLM73_RS01215	COG1401	restriction endodeoxyribonuclease activity
CLM73_RS01230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM73_RS01240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS01255	COG0154	amidase activity
CLM73_RS01265	COG0583	DNA-binding transcription factor activity
CLM73_RS01270	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS01290	COG0583	DNA-binding transcription factor activity
CLM73_RS01320	COG4566	intracellular signal transduction
CLM73_RS01330	COG2814	Major facilitator Superfamily
CLM73_RS01350	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CLM73_RS01355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLM73_RS01365	COG0745	RESPONSE REGULATOR receiver
CLM73_RS01370	COG0642	Histidine kinase
CLM73_RS01465	COG4964	Belongs to the GSP D family
CLM73_RS01485	COG5002	protein histidine kinase activity
CLM73_RS01495	COG0741	lytic transglycosylase activity
CLM73_RS01505	COG0596	Alpha beta hydrolase
CLM73_RS01520	COG0583	DNA-binding transcription factor activity
CLM73_RS01525	COG0861	Integral membrane protein TerC family
CLM73_RS01565	COG0243	molybdopterin cofactor binding
CLM73_RS01575	COG0154	amidase activity
CLM73_RS01585	COG0583	DNA-binding transcription factor activity
CLM73_RS01590	COG1902	pentaerythritol trinitrate reductase activity
CLM73_RS01595	COG0656	L-ascorbic acid biosynthetic process
CLM73_RS01600	COG0583	DNA-binding transcription factor activity
CLM73_RS01610	COG2197	response regulator
CLM73_RS01630	COG2814	Major facilitator Superfamily
CLM73_RS01635	COG0583	DNA-binding transcription factor activity
CLM73_RS01640	COG0604	alcohol dehydrogenase
CLM73_RS01645	COG2423	ornithine cyclodeaminase activity
CLM73_RS01655	COG2200	EAL domain
CLM73_RS01665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLM73_RS01680	COG5001	Diguanylate cyclase
CLM73_RS01685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLM73_RS01725	COG2814	Major facilitator Superfamily
CLM73_RS01740	COG3188	usher protein
CLM73_RS01790	COG1802	Transcriptional regulator
CLM73_RS01800	COG3069	C4-dicarboxylate transmembrane transporter activity
CLM73_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
CLM73_RS01825	COG3064	Membrane
CLM73_RS01875	COG1607	acyl-coa hydrolase
CLM73_RS01885	COG3383	formate dehydrogenase (NAD+) activity
CLM73_RS01885	COG0243	molybdopterin cofactor binding
CLM73_RS01890	COG3383	formate dehydrogenase (NAD+) activity
CLM73_RS01890	COG0243	molybdopterin cofactor binding
CLM73_RS01895	COG0437	4 iron, 4 sulfur cluster binding
CLM73_RS01900	COG2864	formate dehydrogenase
CLM73_RS01915	COG3276	selenocysteine insertion sequence binding
CLM73_RS01930	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CLM73_RS01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM73_RS01945	COG3712	iron ion homeostasis
CLM73_RS01955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM73_RS01965	COG0583	DNA-binding transcription factor activity
CLM73_RS01985	COG1012	belongs to the aldehyde dehydrogenase family
CLM73_RS01990	COG3284	Transcriptional regulator
CLM73_RS01995	COG0134	indole-3-glycerol-phosphate synthase activity
CLM73_RS02000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLM73_RS02005	COG0512	Glutamine amidotransferase of anthranilate synthase
CLM73_RS02015	COG0546	phosphoglycolate phosphatase activity
CLM73_RS02020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLM73_RS02025	COG2967	ApaG domain
CLM73_RS02030	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CLM73_RS02035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM73_RS02040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLM73_RS02045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM73_RS02050	COG0037	tRNA processing
CLM73_RS02075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLM73_RS02095	COG1024	Enoyl-CoA hydratase
CLM73_RS02110	COG0356	it plays a direct role in the translocation of protons across the membrane
CLM73_RS02120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLM73_RS02125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLM73_RS02130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLM73_RS02135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLM73_RS02140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLM73_RS02145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLM73_RS02155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLM73_RS02160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLM73_RS02165	COG0210	DNA helicase
CLM73_RS02170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLM73_RS02180	COG2171	N-acyltransferase activity
CLM73_RS02190	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLM73_RS02200	COG4608	Belongs to the ABC transporter superfamily
CLM73_RS02205	COG0444	Belongs to the ABC transporter superfamily
CLM73_RS02210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS02215	COG0601	transmembrane transport
CLM73_RS02220	COG2988	succinylglutamate desuccinylase activity
CLM73_RS02225	COG0747	negative chemotaxis
CLM73_RS02235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLM73_RS02240	COG1024	Enoyl-CoA hydratase
CLM73_RS02245	COG1024	Enoyl-CoA hydratase
CLM73_RS02270	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM73_RS02285	COG0583	DNA-binding transcription factor activity
CLM73_RS02315	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM73_RS02320	COG1802	Transcriptional regulator
CLM73_RS02325	COG0583	DNA-binding transcription factor activity
CLM73_RS02345	COG2918	glutathione biosynthetic process
CLM73_RS02360	COG2771	luxR family
CLM73_RS02370	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CLM73_RS02375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM73_RS02385	COG2721	sulfolactate sulfo-lyase activity
CLM73_RS02390	COG2721	sulfolactate sulfo-lyase activity
CLM73_RS02395	COG2188	Transcriptional regulator
CLM73_RS02400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM73_RS02405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM73_RS02405	COG2813	Specifically methylates the guanine in position
CLM73_RS02410	COG2223	nitrite transmembrane transporter activity
CLM73_RS02420	COG2860	membrane
CLM73_RS02425	COG1802	Transcriptional regulator
CLM73_RS02435	COG1984	allophanate hydrolase subunit 2
CLM73_RS02440	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CLM73_RS02450	COG0583	DNA-binding transcription factor activity
CLM73_RS02455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM73_RS02465	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CLM73_RS02470	COG0642	Histidine kinase
CLM73_RS02485	COG0745	RESPONSE REGULATOR receiver
CLM73_RS02490	COG2226	methyltransferase
CLM73_RS02505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CLM73_RS02515	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CLM73_RS02530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CLM73_RS02535	COG0351	phosphomethylpyrimidine kinase
CLM73_RS02540	COG2022	thiamine diphosphate biosynthetic process
CLM73_RS02545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLM73_RS02550	COG4771	TonB-dependent receptor
CLM73_RS02565	COG2186	Transcriptional regulator
CLM73_RS02570	COG1063	alcohol dehydrogenase
CLM73_RS02575	COG4948	Mandelate Racemase Muconate Lactonizing
CLM73_RS02580	COG0246	Mannitol dehydrogenase
CLM73_RS02585	COG2226	methyltransferase
CLM73_RS02595	COG1194	a g-specific adenine glycosylase
CLM73_RS02610	COG0477	Major facilitator Superfamily
CLM73_RS02620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CLM73_RS02625	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLM73_RS02645	COG0237	dephospho-CoA kinase activity
CLM73_RS02650	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CLM73_RS02665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM73_RS02675	COG0154	amidase activity
CLM73_RS02690	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLM73_RS02765	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS02770	COG1024	Enoyl-CoA hydratase
CLM73_RS02795	COG2207	Transcriptional regulator
CLM73_RS02810	COG4638	Rieske (2fe-2S)
CLM73_RS02815	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CLM73_RS02820	COG1335	isochorismatase
CLM73_RS02835	COG0741	lytic transglycosylase activity
CLM73_RS02840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CLM73_RS02845	COG0352	thiamine-phosphate diphosphorylase activity
CLM73_RS02860	COG1678	Uncharacterized ACR, COG1678
CLM73_RS02865	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLM73_RS02885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CLM73_RS02895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLM73_RS02900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLM73_RS02910	COG3842	ATPase activity
CLM73_RS02915	COG1175	transmembrane transport
CLM73_RS02935	COG0557	exoribonuclease II activity
CLM73_RS02940	COG3150	esterase
CLM73_RS02945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLM73_RS02950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM73_RS02955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLM73_RS02960	COG0511	ligase activity, forming carbon-carbon bonds
CLM73_RS02965	COG0439	Biotin carboxylase
CLM73_RS02970	COG2264	protein methyltransferase activity
CLM73_RS03005	COG1696	Membrane protein involved in D-alanine export
CLM73_RS03040	COG1522	sequence-specific DNA binding
CLM73_RS03045	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS03065	COG0477	Major facilitator Superfamily
CLM73_RS03070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLM73_RS03075	COG0045	succinate-CoA ligase (ADP-forming) activity
CLM73_RS03075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLM73_RS03075	COG1042	CoA-binding domain protein
CLM73_RS03080	COG1335	isochorismatase
CLM73_RS03085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS03090	COG1116	anion transmembrane transporter activity
CLM73_RS03110	COG3028	Belongs to the UPF0307 family
CLM73_RS03115	COG0312	modulator of DNA gyrase
CLM73_RS03120	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CLM73_RS03130	COG0559	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS03135	COG4177	L-phenylalanine transmembrane transporter activity
CLM73_RS03150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLM73_RS03155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CLM73_RS03160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLM73_RS03170	COG0316	Belongs to the HesB IscA family
CLM73_RS03175	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CLM73_RS03185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLM73_RS03190	COG1881	PFAM PEBP family protein
CLM73_RS03195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLM73_RS03200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLM73_RS03205	COG2207	Transcriptional regulator
CLM73_RS03215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLM73_RS03215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLM73_RS03220	COG2766	serine protein kinase
CLM73_RS03225	COG2718	Belongs to the UPF0229 family
CLM73_RS03230	COG2719	SpoVR family
CLM73_RS03245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLM73_RS03250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS03265	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS03290	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS03310	COG0741	lytic transglycosylase activity
CLM73_RS03310	COG1388	LysM domain
CLM73_RS03315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM73_RS03320	COG2226	methyltransferase
CLM73_RS03325	COG0328	RNA-DNA hybrid ribonuclease activity
CLM73_RS03335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM73_RS03340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLM73_RS03350	COG1671	Belongs to the UPF0178 family
CLM73_RS03365	COG0786	glutamate:sodium symporter activity
CLM73_RS03375	COG0463	Glycosyl transferase, family 2
CLM73_RS03380	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLM73_RS03395	COG0583	DNA-binding transcription factor activity
CLM73_RS03410	COG0583	DNA-binding transcription factor activity
CLM73_RS03420	COG1346	cytolysis
CLM73_RS03430	COG0697	spore germination
CLM73_RS03435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM73_RS03450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLM73_RS03460	COG1522	sequence-specific DNA binding
CLM73_RS03475	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CLM73_RS03480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM73_RS03495	COG0823	Involved in the tonB-independent uptake of proteins
CLM73_RS03505	COG0848	biopolymer transport protein
CLM73_RS03510	COG0811	peptide transport
CLM73_RS03515	COG0824	Thioesterase
CLM73_RS03550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM73_RS03565	COG2084	Dehydrogenase
CLM73_RS03570	COG0405	Gamma-glutamyltransferase
CLM73_RS03605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLM73_RS03610	COG0129	dihydroxy-acid dehydratase activity
CLM73_RS03615	COG4654	Cytochrome c, class I
CLM73_RS03620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLM73_RS03690	COG1473	amidohydrolase
CLM73_RS03695	COG0418	dihydroorotase activity
CLM73_RS03700	COG0488	(ABC) transporter
CLM73_RS03710	COG2001	Belongs to the MraZ family
CLM73_RS03715	COG0275	rRNA processing
CLM73_RS03720	COG3116	cell division
CLM73_RS03730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLM73_RS03735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLM73_RS03740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLM73_RS03750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLM73_RS03755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLM73_RS03760	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLM73_RS03765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CLM73_RS03775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLM73_RS03780	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CLM73_RS03790	COG0739	heme binding
CLM73_RS03795	COG0653	protein targeting
CLM73_RS03810	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS03815	COG0028	Belongs to the TPP enzyme family
CLM73_RS03825	COG1522	sequence-specific DNA binding
CLM73_RS03840	COG2239	Acts as a magnesium transporter
CLM73_RS03850	COG2855	membrane
CLM73_RS03860	COG1473	amidohydrolase
CLM73_RS03865	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS03875	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CLM73_RS03875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM73_RS03880	COG1501	Belongs to the glycosyl hydrolase 31 family
CLM73_RS03885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLM73_RS03890	COG2011	ABC-type metal ion transport system permease component
CLM73_RS03915	COG2197	response regulator
CLM73_RS03940	COG2610	gluconate transmembrane transporter activity
CLM73_RS03955	COG0735	belongs to the Fur family
CLM73_RS03970	COG2818	Glycosylase
CLM73_RS03975	COG1368	sulfuric ester hydrolase activity
CLM73_RS03980	COG2982	Protein involved in outer membrane biogenesis
CLM73_RS03995	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS04015	COG0737	Belongs to the 5'-nucleotidase family
CLM73_RS04190	COG2154	pterin-4-alpha-carbinolamine dehydratase
CLM73_RS04205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM73_RS04215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLM73_RS04230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM73_RS04235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLM73_RS04240	COG1929	Belongs to the glycerate kinase type-1 family
CLM73_RS04245	COG0469	pyruvate kinase activity
CLM73_RS04250	COG0700	Nucleoside recognition
CLM73_RS04260	COG0242	peptide deformylase activity
CLM73_RS04280	COG0204	Acyl-transferase
CLM73_RS04285	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLM73_RS04290	COG0751	glycine-tRNA ligase activity
CLM73_RS04295	COG0752	glycyl-tRNA synthetase alpha subunit
CLM73_RS04315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLM73_RS04320	COG1024	Enoyl-CoA hydratase
CLM73_RS04340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS04345	COG2030	dehydratase
CLM73_RS04350	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS04380	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS04395	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS04400	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS04405	COG1024	Enoyl-CoA hydratase
CLM73_RS04410	COG0583	DNA-binding transcription factor activity
CLM73_RS04415	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CLM73_RS04420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS04430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLM73_RS04440	COG0617	tRNA 3'-terminal CCA addition
CLM73_RS04455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLM73_RS04460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLM73_RS04465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLM73_RS04470	COG0586	Pfam SNARE associated Golgi protein
CLM73_RS04475	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLM73_RS04480	COG0802	atpase or kinase
CLM73_RS04495	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS04505	COG0405	Gamma-glutamyltransferase
CLM73_RS04510	COG0531	amino acid
CLM73_RS04515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS04525	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS04530	COG0583	DNA-binding transcription factor activity
CLM73_RS04540	COG0579	oxidoreductase
CLM73_RS04550	COG0259	pyridoxamine-phosphate oxidase activity
CLM73_RS04565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM73_RS04570	COG1136	(ABC) transporter
CLM73_RS04570	COG0577	efflux transmembrane transporter activity
CLM73_RS04575	COG1538	Outer membrane efflux protein
CLM73_RS04585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLM73_RS04620	COG1595	DNA-templated transcription, initiation
CLM73_RS04635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLM73_RS04645	COG0800	Aldolase
CLM73_RS04660	COG0463	Glycosyl transferase, family 2
CLM73_RS04660	COG1216	Glycosyl transferase, family 2
CLM73_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS04690	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CLM73_RS04705	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS04710	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CLM73_RS04715	COG4638	Rieske (2fe-2S)
CLM73_RS04740	COG0747	negative chemotaxis
CLM73_RS04745	COG0601	transmembrane transport
CLM73_RS04750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS04755	COG0444	Belongs to the ABC transporter superfamily
CLM73_RS04760	COG4608	Belongs to the ABC transporter superfamily
CLM73_RS04775	COG0488	(ABC) transporter
CLM73_RS04790	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CLM73_RS04795	COG2894	cell division
CLM73_RS04800	COG0850	regulation of cytokinetic process
CLM73_RS04810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLM73_RS04815	COG1271	oxidase subunit
CLM73_RS04820	COG1294	oxidase, subunit
CLM73_RS04825	COG0514	ATP-dependent DNA helicase (RecQ)
CLM73_RS04845	COG2255	four-way junction helicase activity
CLM73_RS04855	COG1090	epimerase
CLM73_RS04860	COG0632	four-way junction helicase activity
CLM73_RS04865	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLM73_RS04885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM73_RS04895	COG0006	proline dipeptidase activity
CLM73_RS04910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLM73_RS04915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLM73_RS04930	COG4783	chaperone-mediated protein folding
CLM73_RS04935	COG0429	hydrolase of the alpha beta-hydrolase fold
CLM73_RS04965	COG0513	Belongs to the DEAD box helicase family
CLM73_RS04980	COG1058	Belongs to the CinA family
CLM73_RS04980	COG1546	Belongs to the CinA family
CLM73_RS04985	COG1414	Transcriptional regulator
CLM73_RS05000	COG0167	dihydroorotate dehydrogenase activity
CLM73_RS05005	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CLM73_RS05010	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CLM73_RS05080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLM73_RS05085	COG0735	belongs to the Fur family
CLM73_RS05090	COG0497	DNA recombination
CLM73_RS05100	COG1420	regulation of RNA biosynthetic process
CLM73_RS05105	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CLM73_RS05115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLM73_RS05125	COG0443	Heat shock 70 kDa protein
CLM73_RS05130	COG0484	heat shock protein binding
CLM73_RS05140	COG3547	Transposase (IS116 IS110 IS902 family)
CLM73_RS05150	COG0612	Peptidase, M16
CLM73_RS05175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLM73_RS05205	COG0840	transmembrane signaling receptor activity
CLM73_RS05210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM73_RS05225	COG0745	RESPONSE REGULATOR receiver
CLM73_RS05230	COG2205	protein histidine kinase activity
CLM73_RS05235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CLM73_RS05240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CLM73_RS05245	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CLM73_RS05260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLM73_RS05280	COG1193	negative regulation of DNA recombination
CLM73_RS05285	COG0492	ferredoxin-NADP+ reductase activity
CLM73_RS05290	COG1674	ftsk spoiiie
CLM73_RS05295	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CLM73_RS05305	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CLM73_RS05310	COG0517	IMP dehydrogenase activity
CLM73_RS05310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CLM73_RS05330	COG0601	transmembrane transport
CLM73_RS05345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM73_RS05350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLM73_RS05355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLM73_RS05385	COG0126	phosphoglycerate kinase activity
CLM73_RS05405	COG0477	Major facilitator Superfamily
CLM73_RS05410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM73_RS05415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLM73_RS05435	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS05440	COG3022	response to hydroperoxide
CLM73_RS05445	COG1289	transmembrane transporter activity
CLM73_RS05450	COG0028	Belongs to the TPP enzyme family
CLM73_RS05455	COG0440	acetolactate synthase activity
CLM73_RS05460	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLM73_RS05465	COG1183	phosphatidylcholine synthase activity
CLM73_RS05475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLM73_RS05480	COG1185	polyribonucleotide nucleotidyltransferase activity
CLM73_RS05490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLM73_RS05520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS05530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLM73_RS05545	COG0604	alcohol dehydrogenase
CLM73_RS05545	COG3321	synthase
CLM73_RS05550	COG0149	triose-phosphate isomerase activity
CLM73_RS05555	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLM73_RS05560	COG0583	DNA-binding transcription factor activity
CLM73_RS05565	COG5383	Protein conserved in bacteria
CLM73_RS05610	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CLM73_RS05615	COG4608	Belongs to the ABC transporter superfamily
CLM73_RS05620	COG0444	Belongs to the ABC transporter superfamily
CLM73_RS05625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS05630	COG0601	transmembrane transport
CLM73_RS05635	COG0747	negative chemotaxis
CLM73_RS05730	COG1595	DNA-templated transcription, initiation
CLM73_RS05740	COG4774	siderophore transport
CLM73_RS05770	COG2207	Transcriptional regulator
CLM73_RS05775	COG4221	oxidoreductase activity
CLM73_RS05800	COG2851	Citrate transporter
CLM73_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS05825	COG1278	Cold shock
CLM73_RS05835	COG1595	DNA-templated transcription, initiation
CLM73_RS05865	COG3604	Transcriptional regulator
CLM73_RS05870	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CLM73_RS05880	COG2354	Protein conserved in bacteria
CLM73_RS05890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM73_RS05905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLM73_RS05910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM73_RS05915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM73_RS05930	COG0583	DNA-binding transcription factor activity
CLM73_RS05945	COG1597	lipid kinase activity
CLM73_RS05950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLM73_RS05975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLM73_RS05980	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM73_RS05985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM73_RS05990	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM73_RS05995	COG0649	NAD binding
CLM73_RS06000	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CLM73_RS06010	COG1034	ATP synthesis coupled electron transport
CLM73_RS06015	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CLM73_RS06020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM73_RS06030	COG0713	ATP synthesis coupled electron transport
CLM73_RS06045	COG1007	ATP synthesis coupled electron transport
CLM73_RS06055	COG4774	siderophore transport
CLM73_RS06060	COG0560	Phosphoserine phosphatase
CLM73_RS06065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLM73_RS06070	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CLM73_RS06075	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CLM73_RS06085	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM73_RS06090	COG0450	alkyl hydroperoxide reductase
CLM73_RS06105	COG1214	PFAM Peptidase M22, glycoprotease
CLM73_RS06110	COG1573	uracil-dna glycosylase
CLM73_RS06115	COG0477	Major facilitator Superfamily
CLM73_RS06120	COG1196	nuclear chromosome segregation
CLM73_RS06130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLM73_RS06135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM73_RS06145	COG2917	probably involved in intracellular septation
CLM73_RS06150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLM73_RS06155	COG1122	ATPase activity
CLM73_RS06160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLM73_RS06165	COG1268	BioY protein
CLM73_RS06190	COG1414	Transcriptional regulator
CLM73_RS06195	COG2084	Dehydrogenase
CLM73_RS06200	COG1012	belongs to the aldehyde dehydrogenase family
CLM73_RS06210	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS06220	COG0439	Biotin carboxylase
CLM73_RS06225	COG0511	ligase activity, forming carbon-carbon bonds
CLM73_RS06230	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM73_RS06230	COG1024	Enoyl-CoA hydratase
CLM73_RS06240	COG0183	Belongs to the thiolase family
CLM73_RS06250	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLM73_RS06270	COG0559	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS06295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLM73_RS06330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLM73_RS06335	COG2878	Part of a membrane complex involved in electron transport
CLM73_RS06350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CLM73_RS06360	COG0251	oxidation-reduction process
CLM73_RS06370	COG3228	Belongs to the MtfA family
CLM73_RS06375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLM73_RS06385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLM73_RS06395	COG0159	tryptophan synthase activity
CLM73_RS06400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLM73_RS06405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CLM73_RS06415	COG2721	sulfolactate sulfo-lyase activity
CLM73_RS06430	COG1530	ribonuclease E activity
CLM73_RS06435	COG0564	pseudouridine synthase activity
CLM73_RS06445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CLM73_RS06450	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CLM73_RS06455	COG3023	N-Acetylmuramoyl-L-alanine amidase
CLM73_RS06465	COG0424	maF-like protein
CLM73_RS06470	COG1399	metal-binding, possibly nucleic acid-binding protein
CLM73_RS06475	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CLM73_RS06480	COG0416	fatty acid biosynthetic process
CLM73_RS06485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLM73_RS06490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLM73_RS06495	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS06500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLM73_RS06505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLM73_RS06530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLM73_RS06535	COG0481	GTPase activity
CLM73_RS06540	COG0681	Belongs to the peptidase S26 family
CLM73_RS06545	COG0571	ribonuclease III activity
CLM73_RS06550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLM73_RS06555	COG1381	Involved in DNA repair and RecF pathway recombination
CLM73_RS06575	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS06605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLM73_RS06630	COG0583	DNA-binding transcription factor activity
CLM73_RS06640	COG0791	NLP P60 protein
CLM73_RS06650	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CLM73_RS06660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLM73_RS06665	COG0697	spore germination
CLM73_RS06670	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CLM73_RS06680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLM73_RS06705	COG2153	protein acetylation
CLM73_RS06715	COG1446	asparaginase
CLM73_RS06720	COG4172	Belongs to the ABC transporter superfamily
CLM73_RS06725	COG0747	negative chemotaxis
CLM73_RS06735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS06760	COG0504	CTP synthase activity
CLM73_RS06775	COG0148	phosphopyruvate hydratase activity
CLM73_RS06790	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLM73_RS06800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLM73_RS06830	COG1981	membrane
CLM73_RS06850	COG0039	L-malate dehydrogenase activity
CLM73_RS06855	COG2188	Transcriptional regulator
CLM73_RS06860	COG2009	succinate dehydrogenase
CLM73_RS06865	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CLM73_RS06870	COG1053	succinate dehydrogenase
CLM73_RS06875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLM73_RS06880	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CLM73_RS06885	COG0372	Belongs to the citrate synthase family
CLM73_RS06890	COG3539	Fimbrial protein
CLM73_RS06900	COG3121	Chaperone
CLM73_RS06910	COG3539	Fimbrial protein
CLM73_RS06915	COG3188	usher protein
CLM73_RS06920	COG3121	Chaperone
CLM73_RS06940	COG0281	malic enzyme
CLM73_RS06940	COG0280	phosphate acetyltransferase
CLM73_RS06950	COG1297	OPT oligopeptide transporter protein
CLM73_RS06970	COG0583	DNA-binding transcription factor activity
CLM73_RS06975	COG2814	Major facilitator Superfamily
CLM73_RS06980	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CLM73_RS06985	COG1522	sequence-specific DNA binding
CLM73_RS06990	COG0567	Dehydrogenase, E1 component
CLM73_RS06995	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLM73_RS07000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLM73_RS07005	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLM73_RS07010	COG1595	DNA-templated transcription, initiation
CLM73_RS07015	COG3712	iron ion homeostasis
CLM73_RS07020	COG4774	siderophore transport
CLM73_RS07050	COG2183	response to ionizing radiation
CLM73_RS07055	COG1199	ATP-dependent helicase activity
CLM73_RS07065	COG0564	pseudouridine synthase activity
CLM73_RS07070	COG1496	oxidoreductase activity
CLM73_RS07075	COG3243	poly(R)-hydroxyalkanoic acid synthase
CLM73_RS07080	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS07085	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CLM73_RS07100	COG0672	)-iron permease
CLM73_RS07125	COG3237	CsbD-like
CLM73_RS07135	COG0189	ligase activity
CLM73_RS07135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLM73_RS07140	COG1132	(ABC) transporter
CLM73_RS07155	COG2833	Protein of unknown function (DUF455)
CLM73_RS07160	COG2258	MOSC domain
CLM73_RS07165	COG2951	lytic endotransglycosylase activity
CLM73_RS07190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLM73_RS07200	COG1696	Membrane protein involved in D-alanine export
CLM73_RS07220	COG1215	transferase activity, transferring glycosyl groups
CLM73_RS07230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLM73_RS07285	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CLM73_RS07290	COG0732	type I restriction modification DNA specificity domain
CLM73_RS07295	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CLM73_RS07335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLM73_RS07350	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLM73_RS07355	COG0077	Prephenate dehydratase
CLM73_RS07355	COG1605	Chorismate mutase
CLM73_RS07360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLM73_RS07370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLM73_RS07375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CLM73_RS07395	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CLM73_RS07400	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CLM73_RS07405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM73_RS07420	COG2951	lytic endotransglycosylase activity
CLM73_RS07425	COG0123	including yeast histone deacetylase and acetoin utilization protein
CLM73_RS07450	COG2985	domain, Protein
CLM73_RS07455	COG0450	alkyl hydroperoxide reductase
CLM73_RS07465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CLM73_RS07470	COG4208	sulfate ABC transporter
CLM73_RS07475	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CLM73_RS07480	COG0175	sulfate reduction
CLM73_RS07510	COG0335	large ribosomal subunit rRNA binding
CLM73_RS07520	COG1162	GTPase activity
CLM73_RS07525	COG0501	Belongs to the peptidase M48B family
CLM73_RS07530	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CLM73_RS07535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLM73_RS07540	COG3327	negative regulation of DNA-templated transcription, initiation
CLM73_RS07545	COG3396	Phenylacetate-CoA oxygenase
CLM73_RS07550	COG3460	Phenylacetate-CoA oxygenase
CLM73_RS07555	COG3396	Phenylacetate-CoA oxygenase
CLM73_RS07560	COG2151	metal-sulfur cluster biosynthetic enzyme
CLM73_RS07565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLM73_RS07570	COG1012	belongs to the aldehyde dehydrogenase family
CLM73_RS07575	COG1024	Enoyl-CoA hydratase
CLM73_RS07580	COG2050	protein possibly involved in aromatic compounds catabolism
CLM73_RS07600	COG0254	rRNA binding
CLM73_RS07605	COG3483	tryptophan 2,3-dioxygenase activity
CLM73_RS07610	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CLM73_RS07615	COG2003	Belongs to the UPF0758 family
CLM73_RS07625	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLM73_RS07630	COG0625	glutathione transferase activity
CLM73_RS07635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLM73_RS07640	COG0642	Histidine kinase
CLM73_RS07660	COG0523	cobalamin synthesis protein
CLM73_RS07665	COG0583	DNA-binding transcription factor activity
CLM73_RS07675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLM73_RS07680	COG1187	pseudouridine synthase activity
CLM73_RS07685	COG0779	Required for maturation of 30S ribosomal subunits
CLM73_RS07690	COG0195	Participates in both transcription termination and antitermination
CLM73_RS07690	COG2251	uridine kinase activity
CLM73_RS07695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLM73_RS07700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLM73_RS07705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLM73_RS07710	COG1217	gtp-binding protein TYPA
CLM73_RS07720	COG0583	DNA-binding transcription factor activity
CLM73_RS07745	COG1283	sodium-dependent phosphate transmembrane transporter activity
CLM73_RS07750	COG1760	l-serine dehydratase
CLM73_RS07755	COG0501	Belongs to the peptidase M48B family
CLM73_RS07775	COG0583	DNA-binding transcription factor activity
CLM73_RS07780	COG3842	ATPase activity
CLM73_RS07790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLM73_RS07795	COG1840	ABC-type Fe3 transport system, periplasmic component
CLM73_RS07815	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS07825	COG1722	exodeoxyribonuclease VII activity
CLM73_RS07830	COG0142	geranyltranstransferase activity
CLM73_RS07840	COG1469	GTP cyclohydrolase I activity
CLM73_RS07845	COG3739	integral membrane protein
CLM73_RS07850	COG0360	Binds together with S18 to 16S ribosomal RNA
CLM73_RS07855	COG2965	DNA replication, synthesis of RNA primer
CLM73_RS07860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLM73_RS07865	COG0359	binds to the 23S rRNA
CLM73_RS07875	COG0305	Participates in initiation and elongation during chromosome replication
CLM73_RS07885	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLM73_RS07920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM73_RS07970	COG0540	Belongs to the ATCase OTCase family
CLM73_RS07975	COG3706	GGDEF domain
CLM73_RS08005	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLM73_RS08010	COG2137	regulation of response to DNA damage stimulus
CLM73_RS08030	COG0045	succinate-CoA ligase (ADP-forming) activity
CLM73_RS08035	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CLM73_RS08040	COG0861	Integral membrane protein TerC family
CLM73_RS08045	COG0861	Integral membrane protein TerC family
CLM73_RS08050	COG0181	hydroxymethylbilane synthase activity
CLM73_RS08085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CLM73_RS08090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLM73_RS08100	COG0436	Aminotransferase
CLM73_RS08120	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CLM73_RS08125	COG0308	aminopeptidase N
CLM73_RS08140	COG0312	modulator of DNA gyrase
CLM73_RS08145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLM73_RS08150	COG0277	FAD linked oxidase domain protein
CLM73_RS08155	COG0277	FAD linked oxidase domain protein
CLM73_RS08160	COG0277	FAD linked oxidase domain protein
CLM73_RS08165	COG0247	lactate metabolic process
CLM73_RS08190	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS08195	COG0583	DNA-binding transcription factor activity
CLM73_RS08200	COG0482	sulfurtransferase activity
CLM73_RS08205	COG0730	response to heat
CLM73_RS08210	COG0625	glutathione transferase activity
CLM73_RS08220	COG3909	cytochrome
CLM73_RS08265	COG0697	spore germination
CLM73_RS08290	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLM73_RS08295	COG3657	addiction module killer protein
CLM73_RS08305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CLM73_RS08325	COG0069	glutamate synthase activity
CLM73_RS08330	COG2391	methyltransferase activity
CLM73_RS08365	COG0557	exoribonuclease II activity
CLM73_RS08370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLM73_RS08375	COG0626	cystathionine gamma-synthase activity
CLM73_RS08380	COG3128	pkhd-type hydroxylase
CLM73_RS08385	COG0776	regulation of translation
CLM73_RS08415	COG0642	Histidine kinase
CLM73_RS08420	COG3158	transport of potassium into the cell
CLM73_RS08425	COG0137	argininosuccinate synthase activity
CLM73_RS08430	COG0583	DNA-binding transcription factor activity
CLM73_RS08455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLM73_RS08460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLM73_RS08470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CLM73_RS08470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS08480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLM73_RS08485	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CLM73_RS08495	COG3642	lipopolysaccharide core region biosynthetic process
CLM73_RS08505	COG3842	ATPase activity
CLM73_RS08510	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLM73_RS08515	COG1177	transmembrane transport
CLM73_RS08535	COG1322	Protein conserved in bacteria
CLM73_RS08545	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS08550	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLM73_RS08555	COG0704	Plays a role in the regulation of phosphate uptake
CLM73_RS08565	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CLM73_RS08570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLM73_RS08570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CLM73_RS08575	COG0765	amino acid transport
CLM73_RS08580	COG0765	amino acid transport
CLM73_RS08590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS08605	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS08610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM73_RS08615	COG0583	DNA-binding transcription factor activity
CLM73_RS08625	COG0277	FAD linked oxidase domain protein
CLM73_RS08630	COG1643	Atp-dependent helicase
CLM73_RS08645	COG0438	transferase activity, transferring glycosyl groups
CLM73_RS08650	COG0726	polysaccharide deacetylase
CLM73_RS08665	COG0726	polysaccharide deacetylase
CLM73_RS08690	COG1132	(ABC) transporter
CLM73_RS08695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLM73_RS08695	COG0475	glutathione-regulated potassium exporter activity
CLM73_RS08705	COG2203	Gaf domain
CLM73_RS08705	COG3706	GGDEF domain
CLM73_RS08705	COG5001	Diguanylate cyclase
CLM73_RS08705	COG4251	negative regulation of phosphorylation
CLM73_RS08715	COG1530	ribonuclease E activity
CLM73_RS08745	COG2204	response regulator
CLM73_RS08750	COG4191	Histidine kinase
CLM73_RS08755	COG1301	dicarboxylic acid transport
CLM73_RS08765	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLM73_RS08770	COG0799	negative regulation of ribosome biogenesis
CLM73_RS08775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLM73_RS08785	COG0151	Belongs to the GarS family
CLM73_RS08790	COG0217	transcriptional regulatory protein
CLM73_RS08795	COG0433	COG0433 Predicted ATPase
CLM73_RS08800	COG0473	3-isopropylmalate dehydrogenase activity
CLM73_RS08810	COG2814	Major facilitator Superfamily
CLM73_RS08815	COG1566	PFAM secretion protein HlyD family protein
CLM73_RS08825	COG1846	Transcriptional regulator
CLM73_RS08845	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLM73_RS08850	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CLM73_RS08875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLM73_RS08900	COG2311	Membrane
CLM73_RS08905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLM73_RS08930	COG0662	Cupin 2, conserved barrel domain protein
CLM73_RS08935	COG5285	phytanoyl-CoA dioxygenase
CLM73_RS08940	COG3217	Mosc domain protein beta barrel domain protein
CLM73_RS08940	COG0633	Ferredoxin
CLM73_RS08945	COG2076	Multidrug Resistance protein
CLM73_RS08960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM73_RS09010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLM73_RS09015	COG0425	Belongs to the sulfur carrier protein TusA family
CLM73_RS09025	COG0228	four-way junction DNA binding
CLM73_RS09030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLM73_RS09035	COG0336	Belongs to the RNA methyltransferase TrmD family
CLM73_RS09040	COG1396	sequence-specific DNA binding
CLM73_RS09045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS09050	COG0765	amino acid transport
CLM73_RS09055	COG1126	abc transporter atp-binding protein
CLM73_RS09060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM73_RS09065	COG0525	valine-tRNA ligase activity
CLM73_RS09070	COG0105	UTP biosynthetic process
CLM73_RS09075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLM73_RS09095	COG2976	Protein conserved in bacteria
CLM73_RS09100	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLM73_RS09105	COG1160	GTP binding
CLM73_RS09110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLM73_RS09115	COG1923	regulation of RNA biosynthetic process
CLM73_RS09120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLM73_RS09125	COG0330	HflC and HflK could
CLM73_RS09130	COG0330	HflC and HflK could
CLM73_RS09135	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CLM73_RS09140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLM73_RS09145	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CLM73_RS09150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CLM73_RS09170	COG0582	viral genome integration into host DNA
CLM73_RS09210	COG4964	Belongs to the GSP D family
CLM73_RS09240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLM73_RS09245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLM73_RS09255	COG1295	ribonuclease BN
CLM73_RS09265	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CLM73_RS09275	COG2205	protein histidine kinase activity
CLM73_RS09290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLM73_RS09295	COG4783	chaperone-mediated protein folding
CLM73_RS09320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM73_RS09335	COG1538	Outer membrane efflux protein
CLM73_RS09355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLM73_RS09365	COG0101	tRNA pseudouridine synthase activity
CLM73_RS09370	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CLM73_RS09375	COG0135	phosphoribosylanthranilate isomerase activity
CLM73_RS09395	COG0129	dihydroxy-acid dehydratase activity
CLM73_RS09400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLM73_RS09405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS09410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CLM73_RS09415	COG1609	Transcriptional regulator
CLM73_RS09425	COG2375	cellular response to nickel ion
CLM73_RS09425	COG1132	(ABC) transporter
CLM73_RS09430	COG1132	(ABC) transporter
CLM73_RS09435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM73_RS09440	COG4605	iron ion homeostasis
CLM73_RS09445	COG4604	ABC transporter, ATP-binding protein
CLM73_RS09450	COG4607	ABC-type enterochelin transport system periplasmic component
CLM73_RS09455	COG4774	siderophore transport
CLM73_RS09475	COG4172	Belongs to the ABC transporter superfamily
CLM73_RS09480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS09485	COG0601	transmembrane transport
CLM73_RS09510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLM73_RS09515	COG2197	response regulator
CLM73_RS09520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLM73_RS09525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLM73_RS09540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLM73_RS09545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLM73_RS09550	COG0004	ammonium transporteR
CLM73_RS09555	COG0347	Belongs to the P(II) protein family
CLM73_RS09560	COG2960	long-chain fatty acid transporting porin activity
CLM73_RS09575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLM73_RS09585	COG0156	8-amino-7-oxononanoate synthase activity
CLM73_RS09595	COG0574	Belongs to the PEP-utilizing enzyme family
CLM73_RS09595	COG3848	Pyruvate phosphate dikinase
CLM73_RS09600	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLM73_RS09620	COG2197	response regulator
CLM73_RS09655	COG0606	chelatase, subunit chli
CLM73_RS09660	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CLM73_RS09665	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLM73_RS09670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLM73_RS09675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLM73_RS09675	COG0072	phenylalanine-tRNA ligase activity
CLM73_RS09705	COG0384	phenazine biosynthesis protein PhzF
CLM73_RS09710	COG0456	acetyltransferase
CLM73_RS09735	COG1522	sequence-specific DNA binding
CLM73_RS09775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM73_RS09785	COG1116	anion transmembrane transporter activity
CLM73_RS09800	COG0583	DNA-binding transcription factor activity
CLM73_RS09815	COG5265	(ABC) transporter
CLM73_RS09820	COG0656	L-ascorbic acid biosynthetic process
CLM73_RS09835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CLM73_RS09850	COG2223	nitrite transmembrane transporter activity
CLM73_RS09860	COG1215	transferase activity, transferring glycosyl groups
CLM73_RS09865	COG0726	polysaccharide deacetylase
CLM73_RS09865	COG1649	PFAM Uncharacterised BCR, COG1649
CLM73_RS09870	COG0457	Tetratricopeptide repeat
CLM73_RS09900	COG1610	YqeY-like protein
CLM73_RS09910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLM73_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS09925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLM73_RS09960	COG1216	Glycosyl transferase, family 2
CLM73_RS09965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLM73_RS09975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLM73_RS09980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLM73_RS09995	COG2091	lysine biosynthetic process via aminoadipic acid
CLM73_RS10010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM73_RS10015	COG0697	spore germination
CLM73_RS10020	COG0506	proline dehydrogenase activity
CLM73_RS10035	COG0583	DNA-binding transcription factor activity
CLM73_RS10055	COG2814	Major facilitator Superfamily
CLM73_RS10060	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS10065	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS10100	COG3245	cytochrome
CLM73_RS10105	COG1280	lysine exporter protein (LysE YggA)
CLM73_RS10120	COG1280	lysine exporter protein (LysE YggA)
CLM73_RS10140	COG0697	spore germination
CLM73_RS10145	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CLM73_RS10150	COG0697	spore germination
CLM73_RS10165	COG1024	Enoyl-CoA hydratase
CLM73_RS10170	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS10180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLM73_RS10185	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CLM73_RS10190	COG0667	Aldo Keto reductase
CLM73_RS10195	COG0583	DNA-binding transcription factor activity
CLM73_RS10205	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CLM73_RS10275	COG4235	cytochrome complex assembly
CLM73_RS10285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM73_RS10295	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CLM73_RS10315	COG4133	protoheme IX ABC transporter activity
CLM73_RS10320	COG3005	denitrification pathway
CLM73_RS10325	COG3043	anaerobic respiration
CLM73_RS10345	COG3246	L-lysine catabolic process to acetate
CLM73_RS10350	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM73_RS10355	COG0583	DNA-binding transcription factor activity
CLM73_RS10380	COG1595	DNA-templated transcription, initiation
CLM73_RS10390	COG0129	dihydroxy-acid dehydratase activity
CLM73_RS10395	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS10400	COG5001	Diguanylate cyclase
CLM73_RS10405	COG1024	Enoyl-CoA hydratase
CLM73_RS10410	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS10415	COG0583	DNA-binding transcription factor activity
CLM73_RS10420	COG2610	gluconate transmembrane transporter activity
CLM73_RS10425	COG2226	methyltransferase
CLM73_RS10445	COG2188	Transcriptional regulator
CLM73_RS10450	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS10470	COG4977	sequence-specific DNA binding
CLM73_RS10485	COG1280	lysine exporter protein (LysE YggA)
CLM73_RS10490	COG5265	(ABC) transporter
CLM73_RS10495	COG1132	(ABC) transporter
CLM73_RS10510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS10555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM73_RS10565	COG1487	ribonuclease activity
CLM73_RS10570	COG4691	Plasmid stability protein
CLM73_RS10575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CLM73_RS10610	COG0307	riboflavin synthase, alpha
CLM73_RS10620	COG0154	amidase activity
CLM73_RS10625	COG0747	negative chemotaxis
CLM73_RS10630	COG0601	transmembrane transport
CLM73_RS10635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS10640	COG4172	Belongs to the ABC transporter superfamily
CLM73_RS10650	COG0657	acetylesterase activity
CLM73_RS10655	COG2808	Putative FMN-binding domain
CLM73_RS10660	COG0235	Class ii aldolase
CLM73_RS10665	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CLM73_RS10670	COG4166	transmembrane transport
CLM73_RS10680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLM73_RS10700	COG2207	Transcriptional regulator
CLM73_RS10700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLM73_RS10710	COG0789	Transcriptional regulator
CLM73_RS10730	COG4774	siderophore transport
CLM73_RS10740	COG0022	dehydrogenase e1 component
CLM73_RS10770	COG0165	Argininosuccinate lyase
CLM73_RS10775	COG0668	transmembrane transport
CLM73_RS10835	COG2165	general secretion pathway protein
CLM73_RS10865	COG0583	DNA-binding transcription factor activity
CLM73_RS10880	COG0601	transmembrane transport
CLM73_RS10885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS10890	COG4172	Belongs to the ABC transporter superfamily
CLM73_RS10895	COG1280	lysine exporter protein (LysE YggA)
CLM73_RS10900	COG4681	YaeQ
CLM73_RS10910	COG0300	oxidoreductase activity
CLM73_RS10935	COG2188	Transcriptional regulator
CLM73_RS10965	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLM73_RS10970	COG0066	3-isopropylmalate dehydratase activity
CLM73_RS10990	COG3976	FMN-binding domain protein
CLM73_RS10990	COG1053	succinate dehydrogenase
CLM73_RS11000	COG3161	chorismate lyase activity
CLM73_RS11005	COG1187	pseudouridine synthase activity
CLM73_RS11010	COG0583	DNA-binding transcription factor activity
CLM73_RS11035	COG1999	signal sequence binding
CLM73_RS11040	COG0339	signal peptide processing
CLM73_RS11045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLM73_RS11050	COG4566	intracellular signal transduction
CLM73_RS11065	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLM73_RS11070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLM73_RS11075	COG2807	transmembrane transport
CLM73_RS11080	COG1846	Transcriptional regulator
CLM73_RS11090	COG4797	methyltransferase
CLM73_RS11090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLM73_RS11100	COG1191	sigma factor activity
CLM73_RS11120	COG1360	Flagellar Motor Protein
CLM73_RS11125	COG0745	RESPONSE REGULATOR receiver
CLM73_RS11135	COG0835	chemotaxis
CLM73_RS11140	COG0840	transmembrane signaling receptor activity
CLM73_RS11145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLM73_RS11150	COG2201	protein-glutamate methylesterase activity
CLM73_RS11155	COG0745	RESPONSE REGULATOR receiver
CLM73_RS11160	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CLM73_RS11175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLM73_RS11190	COG2747	anti-sigma28 factor FlgM
CLM73_RS11205	COG1558	bacterial-type flagellum-dependent cell motility
CLM73_RS11215	COG1749	Flagellar hook protein flgE
CLM73_RS11220	COG4787	bacterial-type flagellum-dependent cell motility
CLM73_RS11260	COG0840	transmembrane signaling receptor activity
CLM73_RS11270	COG0840	transmembrane signaling receptor activity
CLM73_RS11275	COG0840	transmembrane signaling receptor activity
CLM73_RS11330	COG1317	bacterial-type flagellum organization
CLM73_RS11335	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLM73_RS11340	COG1766	The M ring may be actively involved in energy transduction
CLM73_RS11345	COG1677	Flagellar hook-basal body complex protein FliE
CLM73_RS11355	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLM73_RS11375	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CLM73_RS11380	COG1334	flagellar protein FlaG
CLM73_RS11395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS11400	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS11410	COG0285	dihydrofolate synthase activity
CLM73_RS11430	COG1451	nucleotide metabolic process
CLM73_RS11435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CLM73_RS11445	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CLM73_RS11450	COG0024	Methionine aminopeptidase
CLM73_RS11455	COG0052	Belongs to the universal ribosomal protein uS2 family
CLM73_RS11460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLM73_RS11465	COG0528	UMP kinase activity
CLM73_RS11470	COG0233	cytoplasmic translational termination
CLM73_RS11475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLM73_RS11480	COG0575	Belongs to the CDS family
CLM73_RS11485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CLM73_RS11490	COG0750	zinc metalloprotease
CLM73_RS11495	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLM73_RS11500	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CLM73_RS11505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM73_RS11510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLM73_RS11525	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLM73_RS11530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLM73_RS11590	COG2169	Transcriptional regulator
CLM73_RS11590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLM73_RS11595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLM73_RS11595	COG0519	Catalyzes the synthesis of GMP from XMP
CLM73_RS11605	COG0330	HflC and HflK could
CLM73_RS11615	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLM73_RS11620	COG2867	negative regulation of translational initiation
CLM73_RS11630	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS11635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CLM73_RS11660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLM73_RS11665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLM73_RS11670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLM73_RS11675	COG0084	hydrolase, TatD family'
CLM73_RS11690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS11695	COG0765	amino acid transport
CLM73_RS11700	COG1126	abc transporter atp-binding protein
CLM73_RS11705	COG0010	Belongs to the arginase family
CLM73_RS11710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLM73_RS11735	COG0625	glutathione transferase activity
CLM73_RS11745	COG1522	sequence-specific DNA binding
CLM73_RS11750	COG0386	Belongs to the glutathione peroxidase family
CLM73_RS11760	COG0840	transmembrane signaling receptor activity
CLM73_RS11770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS11815	COG0513	Belongs to the DEAD box helicase family
CLM73_RS11825	COG1414	Transcriptional regulator
CLM73_RS11840	COG0747	negative chemotaxis
CLM73_RS11845	COG0601	transmembrane transport
CLM73_RS11850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS11860	COG4608	Belongs to the ABC transporter superfamily
CLM73_RS11865	COG1228	amidohydrolase
CLM73_RS11890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS11895	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CLM73_RS11900	COG4521	taurine ABC transporter
CLM73_RS11920	COG1966	Carbon starvation protein
CLM73_RS11925	COG2879	small protein
CLM73_RS11935	COG0783	Belongs to the Dps family
CLM73_RS11945	COG0384	phenazine biosynthesis protein PhzF
CLM73_RS11960	COG4172	Belongs to the ABC transporter superfamily
CLM73_RS11965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS11970	COG0601	transmembrane transport
CLM73_RS11975	COG0747	negative chemotaxis
CLM73_RS11985	COG4774	siderophore transport
CLM73_RS11990	COG3712	iron ion homeostasis
CLM73_RS12005	COG0583	DNA-binding transcription factor activity
CLM73_RS12015	COG0154	amidase activity
CLM73_RS12025	COG0251	oxidation-reduction process
CLM73_RS12030	COG0583	DNA-binding transcription factor activity
CLM73_RS12035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLM73_RS12040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLM73_RS12045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLM73_RS12055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CLM73_RS12060	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CLM73_RS12065	COG0745	RESPONSE REGULATOR receiver
CLM73_RS12070	COG5002	protein histidine kinase activity
CLM73_RS12075	COG0574	Belongs to the PEP-utilizing enzyme family
CLM73_RS12075	COG3848	Pyruvate phosphate dikinase
CLM73_RS12085	COG0697	spore germination
CLM73_RS12095	COG4941	Belongs to the sigma-70 factor family
CLM73_RS12105	COG3795	YCII-related domain
CLM73_RS12110	COG3795	YCII-related domain
CLM73_RS12125	COG2885	chlorophyll binding
CLM73_RS12125	COG3047	cAMP biosynthetic process
CLM73_RS12130	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLM73_RS12135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLM73_RS12145	COG1683	Conserved Protein
CLM73_RS12160	COG1309	transcriptional regulator
CLM73_RS12170	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS12175	COG0668	transmembrane transport
CLM73_RS12195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM73_RS12205	COG4608	Belongs to the ABC transporter superfamily
CLM73_RS12210	COG0444	Belongs to the ABC transporter superfamily
CLM73_RS12215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS12220	COG0601	transmembrane transport
CLM73_RS12230	COG1802	Transcriptional regulator
CLM73_RS12235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CLM73_RS12245	COG0667	Aldo Keto reductase
CLM73_RS12255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM73_RS12260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM73_RS12280	COG1414	Transcriptional regulator
CLM73_RS12285	COG4106	trans-aconitate 2-methyltransferase activity
CLM73_RS12295	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CLM73_RS12320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM73_RS12330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS12335	COG0765	amino acid transport
CLM73_RS12340	COG0765	amino acid transport
CLM73_RS12360	COG0587	DNA-directed DNA polymerase activity
CLM73_RS12375	COG0833	amino acid
CLM73_RS12380	COG0400	carboxylic ester hydrolase activity
CLM73_RS12390	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS12400	COG0028	Belongs to the TPP enzyme family
CLM73_RS12415	COG1566	PFAM secretion protein HlyD family protein
CLM73_RS12435	COG0720	synthase
CLM73_RS12440	COG0602	queuosine metabolic process
CLM73_RS12460	COG1902	pentaerythritol trinitrate reductase activity
CLM73_RS12490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLM73_RS12505	COG0842	Transport permease protein
CLM73_RS12510	COG1131	(ABC) transporter
CLM73_RS12520	COG1309	transcriptional regulator
CLM73_RS12525	COG2130	NADP-dependent
CLM73_RS12550	COG3842	ATPase activity
CLM73_RS12555	COG3842	ATPase activity
CLM73_RS12565	COG0395	ABC-type sugar transport system, permease component
CLM73_RS12590	COG2199	diguanylate cyclase activity
CLM73_RS12590	COG2203	Gaf domain
CLM73_RS12595	COG3634	alkyl hydroperoxide reductase activity
CLM73_RS12605	COG3387	PFAM Glycoside hydrolase 15-related
CLM73_RS12610	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS12645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM73_RS12650	COG0420	3'-5' exonuclease activity
CLM73_RS12675	COG2111	Na H antiporter
CLM73_RS12675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLM73_RS12680	COG1006	Multisubunit Na H antiporter MnhC subunit
CLM73_RS12685	COG0651	ATP synthesis coupled electron transport
CLM73_RS12690	COG1863	multisubunit Na H antiporter MnhE subunit
CLM73_RS12695	COG2212	antiporter activity
CLM73_RS12715	COG0590	tRNA wobble adenosine to inosine editing
CLM73_RS12720	COG1619	proteins homologs of microcin C7 resistance protein MccF
CLM73_RS12725	COG0488	(ABC) transporter
CLM73_RS12760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM73_RS12765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM73_RS12775	COG2252	PERMEase
CLM73_RS12780	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLM73_RS12785	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CLM73_RS12795	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CLM73_RS12820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLM73_RS12825	COG0789	Transcriptional regulator
CLM73_RS12835	COG2608	mercury ion transmembrane transporter activity
CLM73_RS12840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLM73_RS12840	COG0678	peroxiredoxin activity
CLM73_RS12850	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CLM73_RS12855	COG0584	glycerophosphoryl diester phosphodiesterase
CLM73_RS12865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM73_RS12875	COG4181	ATPase activity
CLM73_RS12895	COG0583	DNA-binding transcription factor activity
CLM73_RS12910	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS12925	COG4336	lyase activity
CLM73_RS12935	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLM73_RS12975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS12980	COG0765	amino acid transport
CLM73_RS12985	COG1126	abc transporter atp-binding protein
CLM73_RS12990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLM73_RS12995	COG1758	RNA polymerase activity
CLM73_RS13000	COG0194	GDP metabolic process
CLM73_RS13005	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS13010	COG0791	NLP P60 protein
CLM73_RS13015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLM73_RS13020	COG0833	amino acid
CLM73_RS13025	COG1561	YicC-like family, N-terminal region
CLM73_RS13030	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLM73_RS13040	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS13045	COG0840	transmembrane signaling receptor activity
CLM73_RS13050	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CLM73_RS13055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLM73_RS13060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLM73_RS13065	COG0174	glutamine synthetase
CLM73_RS13075	COG2204	response regulator
CLM73_RS13080	COG0583	DNA-binding transcription factor activity
CLM73_RS13085	COG1741	Belongs to the pirin family
CLM73_RS13090	COG1741	Belongs to the pirin family
CLM73_RS13100	COG0596	Alpha beta hydrolase
CLM73_RS13115	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS13125	COG3842	ATPase activity
CLM73_RS13135	COG1840	ABC-type Fe3 transport system, periplasmic component
CLM73_RS13170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLM73_RS13175	COG0583	DNA-binding transcription factor activity
CLM73_RS13180	COG0783	Belongs to the Dps family
CLM73_RS13185	COG0300	oxidoreductase activity
CLM73_RS13200	COG1596	polysaccharide export
CLM73_RS13215	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLM73_RS13220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CLM73_RS13255	COG0156	8-amino-7-oxononanoate synthase activity
CLM73_RS13260	COG0604	alcohol dehydrogenase
CLM73_RS13260	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS13260	COG3321	synthase
CLM73_RS13275	COG3842	ATPase activity
CLM73_RS13280	COG0395	ABC-type sugar transport system, permease component
CLM73_RS13285	COG1175	transmembrane transport
CLM73_RS13290	COG1653	transport
CLM73_RS13295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CLM73_RS13325	COG1794	racemase activity, acting on amino acids and derivatives
CLM73_RS13330	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CLM73_RS13340	COG0583	DNA-binding transcription factor activity
CLM73_RS13345	COG0625	glutathione transferase activity
CLM73_RS13350	COG2133	pyrroloquinoline quinone binding
CLM73_RS13360	COG0697	spore germination
CLM73_RS13365	COG2363	Small membrane protein
CLM73_RS13395	COG1414	Transcriptional regulator
CLM73_RS13400	COG0010	Belongs to the arginase family
CLM73_RS13405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLM73_RS13410	COG1464	Belongs to the NlpA lipoprotein family
CLM73_RS13420	COG1408	metallophosphoesterase
CLM73_RS13430	COG0688	phosphatidylethanolamine metabolic process
CLM73_RS13435	COG0488	(ABC) transporter
CLM73_RS13445	COG0745	RESPONSE REGULATOR receiver
CLM73_RS13455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLM73_RS13460	COG3300	MHYT domain
CLM73_RS13460	COG5001	Diguanylate cyclase
CLM73_RS13475	COG2814	Major facilitator Superfamily
CLM73_RS13490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CLM73_RS13495	COG2204	response regulator
CLM73_RS13500	COG2204	response regulator
CLM73_RS13535	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS13565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM73_RS13575	COG1289	transmembrane transporter activity
CLM73_RS13580	COG2199	diguanylate cyclase activity
CLM73_RS13580	COG2200	EAL domain
CLM73_RS13590	COG1640	4-alpha-glucanotransferase
CLM73_RS13595	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLM73_RS13605	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLM73_RS13610	COG0366	Alpha amylase catalytic
CLM73_RS13615	COG0366	Alpha amylase catalytic
CLM73_RS13620	COG0297	glycogen (starch) synthase activity
CLM73_RS13625	COG0028	Belongs to the TPP enzyme family
CLM73_RS13670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM73_RS13675	COG3568	Endonuclease Exonuclease Phosphatase
CLM73_RS13690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS13695	COG4172	Belongs to the ABC transporter superfamily
CLM73_RS13705	COG0659	secondary active sulfate transmembrane transporter activity
CLM73_RS13730	COG1253	flavin adenine dinucleotide binding
CLM73_RS13810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLM73_RS13830	COG2814	Major facilitator Superfamily
CLM73_RS13840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM73_RS13865	COG4774	siderophore transport
CLM73_RS13870	COG3712	iron ion homeostasis
CLM73_RS13880	COG2199	diguanylate cyclase activity
CLM73_RS13895	COG0028	Belongs to the TPP enzyme family
CLM73_RS13905	COG2197	response regulator
CLM73_RS13915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CLM73_RS13920	COG0784	Response regulator, receiver
CLM73_RS13920	COG2205	protein histidine kinase activity
CLM73_RS13940	COG0628	permease
CLM73_RS13945	COG1187	pseudouridine synthase activity
CLM73_RS13965	COG1959	2 iron, 2 sulfur cluster binding
CLM73_RS13975	COG0531	amino acid
CLM73_RS13995	COG3119	arylsulfatase activity
CLM73_RS14005	COG1595	DNA-templated transcription, initiation
CLM73_RS14010	COG3712	iron ion homeostasis
CLM73_RS14015	COG4772	TonB-dependent receptor
CLM73_RS14025	COG1393	Belongs to the ArsC family
CLM73_RS14030	COG0798	PFAM Bile acid sodium symporter
CLM73_RS14040	COG0583	DNA-binding transcription factor activity
CLM73_RS14050	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS14075	COG0047	phosphoribosylformylglycinamidine synthase activity
CLM73_RS14150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLM73_RS14155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLM73_RS14215	COG3119	arylsulfatase activity
CLM73_RS14250	COG0714	Associated with various cellular activities
CLM73_RS14255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CLM73_RS14270	COG1120	ATPase activity
CLM73_RS14280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM73_RS14285	COG4993	Dehydrogenase
CLM73_RS14305	COG4771	TonB-dependent receptor
CLM73_RS14310	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLM73_RS14350	COG0288	reversible hydration of carbon dioxide
CLM73_RS14370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CLM73_RS14380	COG3038	cytochrome b561
CLM73_RS14470	COG1121	(ABC) transporter
CLM73_RS14475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLM73_RS14495	COG2721	sulfolactate sulfo-lyase activity
CLM73_RS14540	COG0028	Belongs to the TPP enzyme family
CLM73_RS14545	COG0583	DNA-binding transcription factor activity
CLM73_RS14555	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS14560	COG3386	PFAM SMP-30 Gluconolaconase
CLM73_RS14565	COG2721	sulfolactate sulfo-lyase activity
CLM73_RS14580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM73_RS14585	COG3547	Transposase (IS116 IS110 IS902 family)
CLM73_RS14590	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS14605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS14610	COG0436	Aminotransferase
CLM73_RS14615	COG4597	amino acid ABC transporter
CLM73_RS14620	COG0765	amino acid transport
CLM73_RS14625	COG1126	abc transporter atp-binding protein
CLM73_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS14640	COG0604	alcohol dehydrogenase
CLM73_RS14640	COG3321	synthase
CLM73_RS14660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS14665	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS14680	COG1116	anion transmembrane transporter activity
CLM73_RS14685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS14695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLM73_RS14710	COG2301	Belongs to the HpcH HpaI aldolase family
CLM73_RS14730	COG2130	NADP-dependent
CLM73_RS14740	COG4774	siderophore transport
CLM73_RS14750	COG0745	RESPONSE REGULATOR receiver
CLM73_RS14760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM73_RS14765	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CLM73_RS14770	COG1120	ATPase activity
CLM73_RS14780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLM73_RS14795	COG0390	transport system, permease component
CLM73_RS14800	COG0577	efflux transmembrane transporter activity
CLM73_RS14800	COG1136	(ABC) transporter
CLM73_RS14805	COG1126	abc transporter atp-binding protein
CLM73_RS14810	COG0765	amino acid transport
CLM73_RS14815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS14820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM73_RS14880	COG4566	intracellular signal transduction
CLM73_RS14895	COG2897	thiosulfate sulfurtransferase activity
CLM73_RS14905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLM73_RS14905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLM73_RS14915	COG0783	Belongs to the Dps family
CLM73_RS14920	COG4191	Histidine kinase
CLM73_RS14925	COG4566	intracellular signal transduction
CLM73_RS14940	COG0583	DNA-binding transcription factor activity
CLM73_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS15000	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS15015	COG1335	isochorismatase
CLM73_RS15030	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS15060	COG1473	amidohydrolase
CLM73_RS15080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLM73_RS15105	COG0583	DNA-binding transcription factor activity
CLM73_RS15120	COG2885	chlorophyll binding
CLM73_RS15130	COG0625	glutathione transferase activity
CLM73_RS15190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM73_RS15200	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS15215	COG3706	GGDEF domain
CLM73_RS15225	COG0384	phenazine biosynthesis protein PhzF
CLM73_RS15230	COG0477	Major facilitator Superfamily
CLM73_RS15240	COG0251	oxidation-reduction process
CLM73_RS15265	COG0693	protein deglycase activity
CLM73_RS15285	COG4774	siderophore transport
CLM73_RS15320	COG2010	Cytochrome c
CLM73_RS15320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLM73_RS15340	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLM73_RS15350	COG2226	methyltransferase
CLM73_RS15360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM73_RS15385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS15390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM73_RS15395	COG1116	anion transmembrane transporter activity
CLM73_RS15395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM73_RS15420	COG1104	cysteine desulfurase activity
CLM73_RS15425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS15430	COG4597	amino acid ABC transporter
CLM73_RS15435	COG3154	lipid carrier protein
CLM73_RS15440	COG0826	peptidase U32
CLM73_RS15445	COG0826	peptidase U32
CLM73_RS15450	COG2197	response regulator
CLM73_RS15455	COG3850	Histidine kinase
CLM73_RS15460	COG1763	Mo-molybdopterin cofactor biosynthetic process
CLM73_RS15465	COG0288	reversible hydration of carbon dioxide
CLM73_RS15470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLM73_RS15475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM73_RS15480	COG2181	nitrate reductase activity
CLM73_RS15485	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CLM73_RS15490	COG1140	nitrate reductase beta subunit
CLM73_RS15495	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CLM73_RS15500	COG2223	nitrite transmembrane transporter activity
CLM73_RS15535	COG1538	Outer membrane efflux protein
CLM73_RS15540	COG1566	PFAM secretion protein HlyD family protein
CLM73_RS15555	COG0583	DNA-binding transcription factor activity
CLM73_RS15590	COG1328	CTP reductase activity
CLM73_RS15605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM73_RS15625	COG2070	2-Nitropropane dioxygenase
CLM73_RS15630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLM73_RS15640	COG0583	DNA-binding transcription factor activity
CLM73_RS15650	COG0583	DNA-binding transcription factor activity
CLM73_RS15655	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS15660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLM73_RS15675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS15685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CLM73_RS15690	COG0154	amidase activity
CLM73_RS15695	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS15700	COG3048	D-serine ammonia-lyase activity
CLM73_RS15710	COG4773	Receptor
CLM73_RS15740	COG2885	chlorophyll binding
CLM73_RS15760	COG2211	Major facilitator Superfamily
CLM73_RS15770	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS15775	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS15820	COG0625	glutathione transferase activity
CLM73_RS15825	COG2032	superoxide dismutase activity
CLM73_RS15830	COG2733	membrane
CLM73_RS15835	COG0628	permease
CLM73_RS15840	COG0583	DNA-binding transcription factor activity
CLM73_RS15845	COG1024	Enoyl-CoA hydratase
CLM73_RS15845	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM73_RS15850	COG0183	Belongs to the thiolase family
CLM73_RS15855	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS15860	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS15865	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS15885	COG0477	Major facilitator Superfamily
CLM73_RS15905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLM73_RS15915	COG1012	belongs to the aldehyde dehydrogenase family
CLM73_RS15920	COG0028	Belongs to the TPP enzyme family
CLM73_RS15920	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CLM73_RS15950	COG0583	DNA-binding transcription factor activity
CLM73_RS15960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM73_RS15960	COG0473	3-isopropylmalate dehydrogenase activity
CLM73_RS15975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM73_RS15980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM73_RS15990	COG1012	belongs to the aldehyde dehydrogenase family
CLM73_RS15995	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS16005	COG0583	DNA-binding transcription factor activity
CLM73_RS16060	COG0583	DNA-binding transcription factor activity
CLM73_RS16070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLM73_RS16075	COG3842	ATPase activity
CLM73_RS16080	COG1840	ABC-type Fe3 transport system, periplasmic component
CLM73_RS16085	COG4149	molybdate abc transporter
CLM73_RS16090	COG2203	Gaf domain
CLM73_RS16090	COG3706	GGDEF domain
CLM73_RS16090	COG4251	negative regulation of phosphorylation
CLM73_RS16090	COG5001	Diguanylate cyclase
CLM73_RS16095	COG2201	protein-glutamate methylesterase activity
CLM73_RS16120	COG0840	transmembrane signaling receptor activity
CLM73_RS16125	COG0154	amidase activity
CLM73_RS16130	COG2382	esterase
CLM73_RS16185	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CLM73_RS16195	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS16210	COG0519	Catalyzes the synthesis of GMP from XMP
CLM73_RS16210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLM73_RS16260	COG0583	DNA-binding transcription factor activity
CLM73_RS16270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM73_RS16295	COG2072	flavoprotein involved in K transport
CLM73_RS16300	COG0601	transmembrane transport
CLM73_RS16305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS16310	COG0444	Belongs to the ABC transporter superfamily
CLM73_RS16315	COG4608	Belongs to the ABC transporter superfamily
CLM73_RS16320	COG0747	negative chemotaxis
CLM73_RS16390	COG2130	NADP-dependent
CLM73_RS16395	COG0583	DNA-binding transcription factor activity
CLM73_RS16435	COG1335	isochorismatase
CLM73_RS16460	COG2353	YceI-like domain
CLM73_RS16485	COG0583	DNA-binding transcription factor activity
CLM73_RS16505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLM73_RS16505	COG0047	phosphoribosylformylglycinamidine synthase activity
CLM73_RS16515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS16515	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CLM73_RS16520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLM73_RS16530	COG0613	PHP domain protein
CLM73_RS16540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLM73_RS16550	COG0583	DNA-binding transcription factor activity
CLM73_RS16555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLM73_RS16555	COG2146	nitrite reductase [NAD(P)H] activity
CLM73_RS16565	COG2116	formate transmembrane transporter activity
CLM73_RS16570	COG0515	serine threonine protein kinase
CLM73_RS16580	COG3707	response regulator
CLM73_RS16600	COG1846	Transcriptional regulator
CLM73_RS16620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLM73_RS16625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS16635	COG1850	ribulose-bisphosphate carboxylase activity
CLM73_RS16655	COG0583	DNA-binding transcription factor activity
CLM73_RS16660	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS16675	COG3179	chitinase
CLM73_RS16690	COG0737	Belongs to the 5'-nucleotidase family
CLM73_RS16695	COG4604	ABC transporter, ATP-binding protein
CLM73_RS16700	COG4605	iron ion homeostasis
CLM73_RS16705	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM73_RS16710	COG4607	ABC-type enterochelin transport system periplasmic component
CLM73_RS16715	COG4771	TonB-dependent receptor
CLM73_RS16720	COG0745	RESPONSE REGULATOR receiver
CLM73_RS16730	COG4771	TonB-dependent receptor
CLM73_RS16740	COG1136	(ABC) transporter
CLM73_RS16760	COG2271	Major facilitator Superfamily
CLM73_RS16770	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS16775	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLM73_RS16790	COG0183	Belongs to the thiolase family
CLM73_RS16795	COG1022	Amp-dependent synthetase and ligase
CLM73_RS16830	COG1803	Methylglyoxal synthase
CLM73_RS16835	COG2975	iron-sulfur cluster assembly
CLM73_RS16840	COG0633	Ferredoxin
CLM73_RS16845	COG0443	Heat shock 70 kDa protein
CLM73_RS16850	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CLM73_RS16855	COG0316	Belongs to the HesB IscA family
CLM73_RS16860	COG0822	iron-sulfur transferase activity
CLM73_RS16865	COG1104	cysteine desulfurase activity
CLM73_RS16875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLM73_RS16880	COG0556	nucleotide-excision repair
CLM73_RS16890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLM73_RS16895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLM73_RS16900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLM73_RS16905	COG0740	serine-type endopeptidase activity
CLM73_RS16910	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLM73_RS16915	COG0501	Belongs to the peptidase M48B family
CLM73_RS16925	COG1278	Cold shock
CLM73_RS16940	COG1278	Cold shock
CLM73_RS16995	COG3008	intermembrane lipid transfer
CLM73_RS17000	COG0456	acetyltransferase
CLM73_RS17010	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CLM73_RS17025	COG0277	FAD linked oxidase domain protein
CLM73_RS17030	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLM73_RS17035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLM73_RS17040	COG2271	Major facilitator Superfamily
CLM73_RS17050	COG2200	EAL domain
CLM73_RS17065	COG2171	N-acyltransferase activity
CLM73_RS17075	COG2890	protein-(glutamine-N5) methyltransferase activity
CLM73_RS17080	COG0488	(ABC) transporter
CLM73_RS17090	COG0210	DNA helicase
CLM73_RS17110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLM73_RS17115	COG0196	riboflavin kinase activity
CLM73_RS17120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLM73_RS17125	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLM73_RS17130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLM73_RS17185	COG1902	pentaerythritol trinitrate reductase activity
CLM73_RS17190	COG1126	abc transporter atp-binding protein
CLM73_RS17195	COG0765	amino acid transport
CLM73_RS17200	COG0765	amino acid transport
CLM73_RS17205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS17215	COG1764	response to oxidative stress
CLM73_RS17220	COG1914	H( )-stimulated, divalent metal cation uptake system
CLM73_RS17235	COG2271	Major facilitator Superfamily
CLM73_RS17240	COG1802	Transcriptional regulator
CLM73_RS17245	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS17250	COG1024	Enoyl-CoA hydratase
CLM73_RS17255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS17275	COG0559	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS17285	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CLM73_RS17285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CLM73_RS17285	COG0506	proline dehydrogenase activity
CLM73_RS17295	COG3008	intermembrane lipid transfer
CLM73_RS17300	COG2995	paraquat-inducible protein a
CLM73_RS17305	COG0542	response to heat
CLM73_RS17310	COG4953	penicillin-binding protein 1C
CLM73_RS17320	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CLM73_RS17325	COG1278	Cold shock
CLM73_RS17335	COG0183	Belongs to the thiolase family
CLM73_RS17340	COG0038	chloride channel
CLM73_RS17350	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLM73_RS17365	COG0811	peptide transport
CLM73_RS17380	COG2835	tetraacyldisaccharide 4'-kinase activity
CLM73_RS17385	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CLM73_RS17390	COG0563	adenylate kinase activity
CLM73_RS17405	COG0728	peptidoglycan biosynthetic process
CLM73_RS17415	COG0268	Binds directly to 16S ribosomal RNA
CLM73_RS17420	COG0583	DNA-binding transcription factor activity
CLM73_RS17435	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CLM73_RS17440	COG2186	Transcriptional regulator
CLM73_RS17450	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS17455	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS17460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM73_RS17480	COG0730	response to heat
CLM73_RS17505	COG4774	siderophore transport
CLM73_RS17510	COG3712	iron ion homeostasis
CLM73_RS17515	COG1595	DNA-templated transcription, initiation
CLM73_RS17525	COG1234	tRNA 3'-trailer cleavage
CLM73_RS17535	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS17540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLM73_RS17550	COG1562	ergosterol biosynthetic process
CLM73_RS17560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM73_RS17585	COG0583	DNA-binding transcription factor activity
CLM73_RS17595	COG2188	Transcriptional regulator
CLM73_RS17600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLM73_RS17625	COG1477	protein flavinylation
CLM73_RS17640	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CLM73_RS17655	COG5564	TIM-barrel signal transduction protein
CLM73_RS17660	COG5441	Belongs to the UPF0261 family
CLM73_RS17675	COG0542	response to heat
CLM73_RS17685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLM73_RS17720	COG0494	nUDIX hydrolase
CLM73_RS17725	COG0443	Heat shock 70 kDa protein
CLM73_RS17735	COG3530	Putative quorum-sensing-regulated virulence factor
CLM73_RS17785	COG1522	sequence-specific DNA binding
CLM73_RS17790	COG0488	(ABC) transporter
CLM73_RS17815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS17840	COG2951	lytic endotransglycosylase activity
CLM73_RS17860	COG0583	DNA-binding transcription factor activity
CLM73_RS17875	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS17880	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS17890	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CLM73_RS17910	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS17930	COG2326	polyphosphate kinase activity
CLM73_RS17950	COG2011	ABC-type metal ion transport system permease component
CLM73_RS17955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLM73_RS17960	COG1464	Belongs to the NlpA lipoprotein family
CLM73_RS17980	COG1228	amidohydrolase
CLM73_RS17985	COG0596	Alpha beta hydrolase
CLM73_RS17990	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM73_RS17995	COG2207	Transcriptional regulator
CLM73_RS18015	COG0840	transmembrane signaling receptor activity
CLM73_RS18020	COG2169	Transcriptional regulator
CLM73_RS18045	COG1272	protein, Hemolysin III
CLM73_RS18055	COG0842	Transport permease protein
CLM73_RS18060	COG1131	(ABC) transporter
CLM73_RS18075	COG0348	domain, Protein
CLM73_RS18095	COG3278	Belongs to the heme-copper respiratory oxidase family
CLM73_RS18110	COG4106	trans-aconitate 2-methyltransferase activity
CLM73_RS18110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CLM73_RS18115	COG0583	DNA-binding transcription factor activity
CLM73_RS18120	COG1064	alcohol dehydrogenase
CLM73_RS18130	COG2224	Isocitrate lyase
CLM73_RS18135	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLM73_RS18135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLM73_RS18140	COG1858	cytochrome C peroxidase
CLM73_RS18150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLM73_RS18165	COG0736	holo-[acyl-carrier-protein] synthase activity
CLM73_RS18170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CLM73_RS18180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM73_RS18185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM73_RS18210	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CLM73_RS18215	COG4149	molybdate abc transporter
CLM73_RS18220	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLM73_RS18225	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CLM73_RS18245	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CLM73_RS18250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM73_RS18250	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CLM73_RS18255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM73_RS18260	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CLM73_RS18265	COG4120	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS18275	COG0667	Aldo Keto reductase
CLM73_RS18285	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS18290	COG1024	Enoyl-CoA hydratase
CLM73_RS18300	COG1802	Transcriptional regulator
CLM73_RS18320	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS18325	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS18340	COG1024	Enoyl-CoA hydratase
CLM73_RS18350	COG0183	Belongs to the thiolase family
CLM73_RS18355	COG1024	Enoyl-CoA hydratase
CLM73_RS18360	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS18365	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS18375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS18380	COG0583	DNA-binding transcription factor activity
CLM73_RS18385	COG0517	IMP dehydrogenase activity
CLM73_RS18430	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLM73_RS18450	COG3384	dioxygenase
CLM73_RS18465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLM73_RS18480	COG2204	response regulator
CLM73_RS18520	COG4964	Belongs to the GSP D family
CLM73_RS18570	COG1846	Transcriptional regulator
CLM73_RS18575	COG4172	Belongs to the ABC transporter superfamily
CLM73_RS18580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS18585	COG0601	transmembrane transport
CLM73_RS18600	COG0598	Magnesium transport protein CorA
CLM73_RS18605	COG0210	DNA helicase
CLM73_RS18620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLM73_RS18625	COG1012	belongs to the aldehyde dehydrogenase family
CLM73_RS18635	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLM73_RS18640	COG1045	serine acetyltransferase
CLM73_RS18645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLM73_RS18650	COG0166	Belongs to the GPI family
CLM73_RS18670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLM73_RS18695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM73_RS18715	COG0438	transferase activity, transferring glycosyl groups
CLM73_RS18725	COG0110	maltose O-acetyltransferase activity
CLM73_RS18730	COG0297	glycogen (starch) synthase activity
CLM73_RS18735	COG2197	response regulator
CLM73_RS18740	COG2197	response regulator
CLM73_RS18775	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM73_RS18775	COG1024	Enoyl-CoA hydratase
CLM73_RS18780	COG0183	Belongs to the thiolase family
CLM73_RS18795	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS18800	COG4774	siderophore transport
CLM73_RS18810	COG3395	kinase activity
CLM73_RS18815	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLM73_RS18830	COG3485	protocatechuate 3,4-dioxygenase
CLM73_RS18835	COG3485	protocatechuate 3,4-dioxygenase
CLM73_RS18840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS18845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CLM73_RS18850	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLM73_RS18855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLM73_RS18860	COG1414	Transcriptional regulator
CLM73_RS18870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLM73_RS18885	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS18890	COG1609	Transcriptional regulator
CLM73_RS18905	COG1595	DNA-templated transcription, initiation
CLM73_RS18925	COG1764	response to oxidative stress
CLM73_RS18935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM73_RS18940	COG0583	DNA-binding transcription factor activity
CLM73_RS18945	COG2186	Transcriptional regulator
CLM73_RS18950	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM73_RS18955	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS18960	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS18965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLM73_RS18975	COG1024	Enoyl-CoA hydratase
CLM73_RS18985	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS18995	COG1414	Transcriptional regulator
CLM73_RS19005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLM73_RS19020	COG0583	DNA-binding transcription factor activity
CLM73_RS19060	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CLM73_RS19065	COG0583	DNA-binding transcription factor activity
CLM73_RS19070	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS19125	COG0825	malonyl-CoA metabolic process
CLM73_RS19135	COG0215	cysteine-tRNA ligase activity
CLM73_RS19150	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM73_RS19155	COG1968	undecaprenyl-diphosphatase activity
CLM73_RS19160	COG1253	flavin adenine dinucleotide binding
CLM73_RS19175	COG4263	nitrous-oxide reductase activity
CLM73_RS19190	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CLM73_RS19205	COG0625	glutathione transferase activity
CLM73_RS19210	COG1017	nitric oxide dioxygenase activity
CLM73_RS19210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLM73_RS19215	COG0483	inositol monophosphate 1-phosphatase activity
CLM73_RS19235	COG0668	transmembrane transport
CLM73_RS19265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM73_RS19270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS19290	COG1802	Transcriptional regulator
CLM73_RS19315	COG3360	Dodecin
CLM73_RS19325	COG0583	DNA-binding transcription factor activity
CLM73_RS19330	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS19355	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLM73_RS19360	COG2850	peptidyl-arginine hydroxylation
CLM73_RS19370	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CLM73_RS19375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM73_RS19380	COG1994	Peptidase M50
CLM73_RS19385	COG0009	L-threonylcarbamoyladenylate synthase
CLM73_RS19390	COG2321	neutral zinc metallopeptidase
CLM73_RS19445	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CLM73_RS19460	COG0490	domain, Protein
CLM73_RS19460	COG0471	metal ion transport
CLM73_RS19500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM73_RS19525	COG4191	Histidine kinase
CLM73_RS19525	COG0784	Response regulator, receiver
CLM73_RS19530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLM73_RS19565	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS19575	COG3685	Protein conserved in bacteria
CLM73_RS19615	COG0387	Pfam Sodium calcium exchanger
CLM73_RS19650	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CLM73_RS19665	COG2755	lipolytic protein G-D-S-L family
CLM73_RS19665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CLM73_RS19730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM73_RS19755	COG2084	Dehydrogenase
CLM73_RS19775	COG1802	Transcriptional regulator
CLM73_RS19805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLM73_RS19810	COG0519	Catalyzes the synthesis of GMP from XMP
CLM73_RS19810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLM73_RS19825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM73_RS19830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLM73_RS19840	COG2080	2 iron, 2 sulfur cluster binding
CLM73_RS19850	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CLM73_RS19865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLM73_RS19880	COG1228	amidohydrolase
CLM73_RS19925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM73_RS19930	COG0765	amino acid transport
CLM73_RS19940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS19945	COG1126	abc transporter atp-binding protein
CLM73_RS19950	COG1012	belongs to the aldehyde dehydrogenase family
CLM73_RS19965	COG2197	response regulator
CLM73_RS19970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM73_RS19975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS19980	COG1116	anion transmembrane transporter activity
CLM73_RS19985	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CLM73_RS20000	COG1396	sequence-specific DNA binding
CLM73_RS20015	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS20020	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS20025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS20030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CLM73_RS20045	COG0183	Belongs to the thiolase family
CLM73_RS20050	COG1024	Enoyl-CoA hydratase
CLM73_RS20050	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM73_RS20065	COG2084	Dehydrogenase
CLM73_RS20070	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS20080	COG1595	DNA-templated transcription, initiation
CLM73_RS20105	COG0384	phenazine biosynthesis protein PhzF
CLM73_RS20120	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS20135	COG1609	Transcriptional regulator
CLM73_RS20145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS20155	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS20160	COG3618	amidohydrolase
CLM73_RS20165	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLM73_RS20170	COG1024	Enoyl-CoA hydratase
CLM73_RS20175	COG3246	L-lysine catabolic process to acetate
CLM73_RS20180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS20190	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS20195	COG2301	Belongs to the HpcH HpaI aldolase family
CLM73_RS20210	COG0559	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS20220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM73_RS20230	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM73_RS20260	COG0300	oxidoreductase activity
CLM73_RS20275	COG1959	2 iron, 2 sulfur cluster binding
CLM73_RS20285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLM73_RS20345	COG1126	abc transporter atp-binding protein
CLM73_RS20350	COG0765	amino acid transport
CLM73_RS20360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS20365	COG0436	Aminotransferase
CLM73_RS20370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM73_RS20385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM73_RS20395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS20410	COG4774	siderophore transport
CLM73_RS20415	COG3712	iron ion homeostasis
CLM73_RS20420	COG1595	DNA-templated transcription, initiation
CLM73_RS20435	COG1802	Transcriptional regulator
CLM73_RS20450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS20455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS20465	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS20500	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS20505	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CLM73_RS20515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS20545	COG1058	Belongs to the CinA family
CLM73_RS20545	COG1546	Belongs to the CinA family
CLM73_RS20555	COG0500	methyltransferase
CLM73_RS20570	COG1201	RNA secondary structure unwinding
CLM73_RS20575	COG1793	dna ligase
CLM73_RS20580	COG1793	dna ligase
CLM73_RS20580	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CLM73_RS20605	COG4774	siderophore transport
CLM73_RS20610	COG3712	iron ion homeostasis
CLM73_RS20615	COG1595	DNA-templated transcription, initiation
CLM73_RS20635	COG1408	metallophosphoesterase
CLM73_RS20650	COG0583	DNA-binding transcription factor activity
CLM73_RS20675	COG4175	Glycine betaine
CLM73_RS20675	COG3448	diguanylate cyclase activity
CLM73_RS20680	COG4176	ABC-type proline glycine betaine transport system permease component
CLM73_RS20700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS20715	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS20730	COG0604	alcohol dehydrogenase
CLM73_RS20735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS20750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS20770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS20790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CLM73_RS20795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLM73_RS20800	COG2814	Major facilitator Superfamily
CLM73_RS20805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CLM73_RS20810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CLM73_RS20840	COG1686	Belongs to the peptidase S11 family
CLM73_RS20850	COG1846	Transcriptional regulator
CLM73_RS20855	COG2814	Major facilitator Superfamily
CLM73_RS20860	COG0495	leucyl-tRNA aminoacylation
CLM73_RS20875	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLM73_RS20890	COG0154	amidase activity
CLM73_RS20900	COG0477	Major facilitator Superfamily
CLM73_RS20910	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM73_RS20925	COG0583	DNA-binding transcription factor activity
CLM73_RS20935	COG0235	Class ii aldolase
CLM73_RS20960	COG0583	DNA-binding transcription factor activity
CLM73_RS20965	COG0427	acetyl-CoA hydrolase
CLM73_RS20970	COG0583	DNA-binding transcription factor activity
CLM73_RS20975	COG1511	domain protein
CLM73_RS20975	COG3264	Mechanosensitive ion channel
CLM73_RS21025	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CLM73_RS21030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLM73_RS21035	COG3958	Transketolase
CLM73_RS21040	COG3959	Transketolase, thiamine diphosphate binding domain
CLM73_RS21045	COG1802	Transcriptional regulator
CLM73_RS21050	COG0371	Dehydrogenase
CLM73_RS21060	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM73_RS21065	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS21090	COG3321	synthase
CLM73_RS21090	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS21090	COG0604	alcohol dehydrogenase
CLM73_RS21095	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS21100	COG0500	methyltransferase
CLM73_RS21130	COG0667	Aldo Keto reductase
CLM73_RS21135	COG2207	Transcriptional regulator
CLM73_RS21145	COG0583	DNA-binding transcription factor activity
CLM73_RS21150	COG1335	isochorismatase
CLM73_RS21170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS21175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLM73_RS21180	COG0583	DNA-binding transcription factor activity
CLM73_RS21225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLM73_RS21250	COG0248	Ppx GppA phosphatase
CLM73_RS21260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLM73_RS21270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLM73_RS21275	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CLM73_RS21280	COG1534	Rna-binding protein
CLM73_RS21285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLM73_RS21290	COG2233	PERMEase
CLM73_RS21310	COG3842	ATPase activity
CLM73_RS21320	COG0406	alpha-ribazole phosphatase activity
CLM73_RS21330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLM73_RS21335	COG0505	Belongs to the CarA family
CLM73_RS21340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLM73_RS21355	COG0745	RESPONSE REGULATOR receiver
CLM73_RS21370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS21380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM73_RS21385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS21400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLM73_RS21410	COG1074	ATP-dependent DNA helicase activity
CLM73_RS21435	COG1686	Belongs to the peptidase S11 family
CLM73_RS21440	COG2814	Major facilitator Superfamily
CLM73_RS21465	COG1609	Transcriptional regulator
CLM73_RS21480	COG0277	FAD linked oxidase domain protein
CLM73_RS21485	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CLM73_RS21490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLM73_RS21495	COG4974	Belongs to the 'phage' integrase family
CLM73_RS21500	COG0583	DNA-binding transcription factor activity
CLM73_RS21505	COG0028	Belongs to the TPP enzyme family
CLM73_RS21510	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS21545	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLM73_RS21590	COG0028	Belongs to the TPP enzyme family
CLM73_RS21605	COG1595	DNA-templated transcription, initiation
CLM73_RS21610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS21625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLM73_RS21630	COG1414	Transcriptional regulator
CLM73_RS21635	COG0009	L-threonylcarbamoyladenylate synthase
CLM73_RS21640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLM73_RS21645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLM73_RS21650	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CLM73_RS21655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CLM73_RS21695	COG0583	DNA-binding transcription factor activity
CLM73_RS21700	COG0405	Gamma-glutamyltransferase
CLM73_RS21725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLM73_RS21735	COG0739	heme binding
CLM73_RS21745	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLM73_RS21755	COG0306	phosphate transporter
CLM73_RS21795	COG0625	glutathione transferase activity
CLM73_RS21810	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLM73_RS21815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLM73_RS21825	COG0126	phosphoglycerate kinase activity
CLM73_RS21830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLM73_RS21835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLM73_RS21840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLM73_RS21845	COG2732	(Barnase) inhibitor
CLM73_RS21855	COG0280	phosphate acetyltransferase
CLM73_RS21855	COG0281	malic enzyme
CLM73_RS21865	COG0436	Aminotransferase
CLM73_RS21870	COG0741	lytic transglycosylase activity
CLM73_RS21875	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLM73_RS21890	COG4575	ribosome binding
CLM73_RS21900	COG0243	molybdopterin cofactor binding
CLM73_RS21905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLM73_RS21910	COG1116	anion transmembrane transporter activity
CLM73_RS21915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM73_RS21920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM73_RS21940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLM73_RS21945	COG2027	D-alanyl-D-alanine carboxypeptidase
CLM73_RS21950	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLM73_RS21955	COG0343	queuine tRNA-ribosyltransferase activity
CLM73_RS21960	COG1862	Preprotein translocase
CLM73_RS21965	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLM73_RS21970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLM73_RS21990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLM73_RS21995	COG1702	phosphate starvation-inducible protein PhoH
CLM73_RS22000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLM73_RS22005	COG4535	Mg2 and Co2 transporter CorC
CLM73_RS22010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CLM73_RS22015	COG0667	Aldo Keto reductase
CLM73_RS22050	COG1366	Belongs to the anti-sigma-factor antagonist family
CLM73_RS22050	COG2202	Pas domain
CLM73_RS22060	COG0697	spore germination
CLM73_RS22070	COG0678	peroxiredoxin activity
CLM73_RS22080	COG0412	Dienelactone hydrolase
CLM73_RS22090	COG0315	cyclic pyranopterin monophosphate synthase activity
CLM73_RS22100	COG0314	molybdopterin synthase activity
CLM73_RS22105	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLM73_RS22110	COG0303	'Molybdopterin
CLM73_RS22115	COG0746	molybdenum cofactor guanylyltransferase activity
CLM73_RS22120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLM73_RS22140	COG3383	formate dehydrogenase (NAD+) activity
CLM73_RS22145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CLM73_RS22155	COG2223	nitrite transmembrane transporter activity
CLM73_RS22165	COG1595	DNA-templated transcription, initiation
CLM73_RS22170	COG3712	iron ion homeostasis
CLM73_RS22190	COG4221	oxidoreductase activity
CLM73_RS22210	COG0583	DNA-binding transcription factor activity
CLM73_RS22215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CLM73_RS22235	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS22270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM73_RS22325	COG0671	phosphoesterase, PA-phosphatase related
CLM73_RS22350	COG0583	DNA-binding transcription factor activity
CLM73_RS22355	COG1666	GTP binding
CLM73_RS22360	COG1120	ATPase activity
CLM73_RS22365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM73_RS22370	COG4558	Periplasmic binding protein
CLM73_RS22375	COG3720	iron ion transport
CLM73_RS22385	COG3712	iron ion homeostasis
CLM73_RS22390	COG1595	DNA-templated transcription, initiation
CLM73_RS22405	COG2378	regulation of single-species biofilm formation
CLM73_RS22415	COG1113	amino acid transport
CLM73_RS22425	COG1522	sequence-specific DNA binding
CLM73_RS22430	COG1272	protein, Hemolysin III
CLM73_RS22435	COG3191	aminopeptidase activity
CLM73_RS22440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS22445	COG0765	amino acid transport
CLM73_RS22450	COG1126	abc transporter atp-binding protein
CLM73_RS22465	COG1999	signal sequence binding
CLM73_RS22480	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CLM73_RS22490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLM73_RS22495	COG1845	cytochrome c oxidase, subunit III
CLM73_RS22520	COG4772	TonB-dependent receptor
CLM73_RS22525	COG2900	Belongs to the SlyX family
CLM73_RS22530	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CLM73_RS22545	COG0281	malic enzyme
CLM73_RS22545	COG0280	phosphate acetyltransferase
CLM73_RS22570	COG0697	spore germination
CLM73_RS22585	COG0583	DNA-binding transcription factor activity
CLM73_RS22615	COG1396	sequence-specific DNA binding
CLM73_RS22620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM73_RS22630	COG3145	DNA-N1-methyladenine dioxygenase activity
CLM73_RS22665	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS22670	COG1285	pathogenesis
CLM73_RS22675	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS22680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLM73_RS22705	COG2706	6-phosphogluconolactonase activity
CLM73_RS22715	COG3712	iron ion homeostasis
CLM73_RS22740	COG3712	iron ion homeostasis
CLM73_RS22755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLM73_RS22760	COG0330	HflC and HflK could
CLM73_RS22780	COG2807	transmembrane transport
CLM73_RS22790	COG2207	Transcriptional regulator
CLM73_RS22795	COG4106	trans-aconitate 2-methyltransferase activity
CLM73_RS22800	COG0861	Integral membrane protein TerC family
CLM73_RS22805	COG0583	DNA-binding transcription factor activity
CLM73_RS22850	COG0477	Major facilitator Superfamily
CLM73_RS22855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLM73_RS22860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLM73_RS22865	COG1845	cytochrome c oxidase, subunit III
CLM73_RS22870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CLM73_RS22885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLM73_RS22895	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLM73_RS22925	COG0519	Catalyzes the synthesis of GMP from XMP
CLM73_RS22950	COG0667	Aldo Keto reductase
CLM73_RS22980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM73_RS23020	COG0028	Belongs to the TPP enzyme family
CLM73_RS23025	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS23030	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS23085	COG1222	aaa ATPase
CLM73_RS23140	COG5183	chlorophyll binding
CLM73_RS23140	COG2133	pyrroloquinoline quinone binding
CLM73_RS23155	COG2814	Major facilitator Superfamily
CLM73_RS23200	COG4774	siderophore transport
CLM73_RS23225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CLM73_RS23230	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CLM73_RS23235	COG2080	2 iron, 2 sulfur cluster binding
CLM73_RS23245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS23245	COG2205	protein histidine kinase activity
CLM73_RS23255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLM73_RS23265	COG0745	RESPONSE REGULATOR receiver
CLM73_RS23285	COG0025	NhaP-type Na H and K H
CLM73_RS23295	COG1609	Transcriptional regulator
CLM73_RS23305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLM73_RS23315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLM73_RS23325	COG4251	negative regulation of phosphorylation
CLM73_RS23325	COG3706	GGDEF domain
CLM73_RS23325	COG2203	Gaf domain
CLM73_RS23325	COG5001	Diguanylate cyclase
CLM73_RS23330	COG0840	transmembrane signaling receptor activity
CLM73_RS23335	COG0438	transferase activity, transferring glycosyl groups
CLM73_RS23390	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS23405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLM73_RS23430	COG1053	succinate dehydrogenase
CLM73_RS23470	COG0583	DNA-binding transcription factor activity
CLM73_RS23475	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS23490	COG1595	DNA-templated transcription, initiation
CLM73_RS23510	COG0523	cobalamin synthesis protein
CLM73_RS23515	COG1469	GTP cyclohydrolase I activity
CLM73_RS23520	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLM73_RS23530	COG0798	PFAM Bile acid sodium symporter
CLM73_RS23555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLM73_RS23615	COG0747	negative chemotaxis
CLM73_RS23620	COG0601	transmembrane transport
CLM73_RS23625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS23635	COG4608	Belongs to the ABC transporter superfamily
CLM73_RS23690	COG1454	alcohol dehydrogenase
CLM73_RS23710	COG2814	Major facilitator Superfamily
CLM73_RS23715	COG0730	response to heat
CLM73_RS23725	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS23770	COG2226	methyltransferase
CLM73_RS23775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLM73_RS23780	COG0459	protein refolding
CLM73_RS23790	COG1846	Transcriptional regulator
CLM73_RS23810	COG1917	Cupin 2, conserved barrel domain protein
CLM73_RS23825	COG0559	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS23835	COG1137	ATPase activity
CLM73_RS23845	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CLM73_RS23850	COG0246	Mannitol dehydrogenase
CLM73_RS23855	COG2721	sulfolactate sulfo-lyase activity
CLM73_RS23860	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM73_RS23865	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS23870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS23880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLM73_RS23885	COG2186	Transcriptional regulator
CLM73_RS23890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLM73_RS23895	COG1252	NADH dehydrogenase
CLM73_RS23900	COG0284	orotidine-5'-phosphate decarboxylase activity
CLM73_RS23905	COG1546	Belongs to the CinA family
CLM73_RS23910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CLM73_RS23920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLM73_RS23925	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLM73_RS23950	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CLM73_RS23955	COG3639	organic phosphonate transmembrane transporter activity
CLM73_RS23960	COG3639	organic phosphonate transmembrane transporter activity
CLM73_RS23980	COG0742	ribosomal rna small subunit methyltransferase
CLM73_RS23985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLM73_RS23990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLM73_RS23995	COG3135	benzoate transporter
CLM73_RS24010	COG0477	Major facilitator Superfamily
CLM73_RS24030	COG0012	GTP binding
CLM73_RS24060	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CLM73_RS24065	COG0840	transmembrane signaling receptor activity
CLM73_RS24080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CLM73_RS24090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM73_RS24105	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CLM73_RS24115	COG0204	Acyl-transferase
CLM73_RS24120	COG1368	sulfuric ester hydrolase activity
CLM73_RS24125	COG2186	Transcriptional regulator
CLM73_RS24130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM73_RS24140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLM73_RS24150	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CLM73_RS24150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLM73_RS24165	COG0745	RESPONSE REGULATOR receiver
CLM73_RS24170	COG0277	FAD linked oxidase domain protein
CLM73_RS24180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLM73_RS24185	COG0166	Belongs to the GPI family
CLM73_RS24190	COG0438	transferase activity, transferring glycosyl groups
CLM73_RS24195	COG0438	transferase activity, transferring glycosyl groups
CLM73_RS24225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CLM73_RS24230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLM73_RS24235	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CLM73_RS24260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM73_RS24265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLM73_RS24280	COG0747	negative chemotaxis
CLM73_RS24285	COG0601	transmembrane transport
CLM73_RS24290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS24295	COG4172	Belongs to the ABC transporter superfamily
CLM73_RS24300	COG0154	amidase activity
CLM73_RS24315	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLM73_RS24315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLM73_RS24320	COG0509	glycine decarboxylation via glycine cleavage system
CLM73_RS24325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CLM73_RS24340	COG2081	HI0933 family
CLM73_RS24360	COG3706	GGDEF domain
CLM73_RS24370	COG0717	Belongs to the dCTP deaminase family
CLM73_RS24385	COG0489	protein tyrosine kinase activity
CLM73_RS24395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLM73_RS24395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLM73_RS24400	COG1054	Belongs to the UPF0176 family
CLM73_RS24430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLM73_RS24435	COG2200	EAL domain
CLM73_RS24450	COG0697	spore germination
CLM73_RS24460	COG3712	iron ion homeostasis
CLM73_RS24485	COG0431	NADPH-dependent FMN reductase
CLM73_RS24485	COG1053	succinate dehydrogenase
CLM73_RS24485	COG3976	FMN-binding domain protein
CLM73_RS24490	COG0583	DNA-binding transcription factor activity
CLM73_RS24495	COG0625	glutathione transferase activity
CLM73_RS24515	COG1024	Enoyl-CoA hydratase
CLM73_RS24525	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS24530	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS24535	COG0583	DNA-binding transcription factor activity
CLM73_RS24540	COG3618	amidohydrolase
CLM73_RS24555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLM73_RS24580	COG2205	protein histidine kinase activity
CLM73_RS24585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLM73_RS24590	COG1764	response to oxidative stress
CLM73_RS24660	COG0559	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS24680	COG1131	(ABC) transporter
CLM73_RS24685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM73_RS24690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM73_RS24695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLM73_RS24715	COG0583	DNA-binding transcription factor activity
CLM73_RS24730	COG2267	carboxylic ester hydrolase activity
CLM73_RS24740	COG3284	Transcriptional regulator
CLM73_RS24795	COG0840	transmembrane signaling receptor activity
CLM73_RS24815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLM73_RS24825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS24830	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS24835	COG2814	Major facilitator Superfamily
CLM73_RS24845	COG0165	Argininosuccinate lyase
CLM73_RS24905	COG3712	iron ion homeostasis
CLM73_RS24915	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS24920	COG3246	L-lysine catabolic process to acetate
CLM73_RS24940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLM73_RS24945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM73_RS24950	COG0583	DNA-binding transcription factor activity
CLM73_RS24960	COG1024	Enoyl-CoA hydratase
CLM73_RS24970	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS24975	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS24985	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS24995	COG0154	amidase activity
CLM73_RS25000	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS25005	COG0583	DNA-binding transcription factor activity
CLM73_RS25010	COG2223	nitrite transmembrane transporter activity
CLM73_RS25020	COG1802	Transcriptional regulator
CLM73_RS25025	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS25030	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS25035	COG0473	3-isopropylmalate dehydrogenase activity
CLM73_RS25040	COG3618	amidohydrolase
CLM73_RS25045	COG0583	DNA-binding transcription factor activity
CLM73_RS25080	COG1132	(ABC) transporter
CLM73_RS25100	COG0583	DNA-binding transcription factor activity
CLM73_RS25125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLM73_RS25130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM73_RS25140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CLM73_RS25155	COG1652	LysM domain
CLM73_RS25160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLM73_RS25165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLM73_RS25180	COG0625	glutathione transferase activity
CLM73_RS25185	COG5002	protein histidine kinase activity
CLM73_RS25240	COG1414	Transcriptional regulator
CLM73_RS25245	COG3734	2-keto-3-deoxy-galactonokinase
CLM73_RS25250	COG0800	Aldolase
CLM73_RS25255	COG4948	Mandelate Racemase Muconate Lactonizing
CLM73_RS25260	COG2271	Major facilitator Superfamily
CLM73_RS25265	COG3657	addiction module killer protein
CLM73_RS25275	COG4172	Belongs to the ABC transporter superfamily
CLM73_RS25280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS25285	COG0601	transmembrane transport
CLM73_RS25290	COG0747	negative chemotaxis
CLM73_RS25310	COG2814	Major facilitator Superfamily
CLM73_RS25315	COG3550	peptidyl-serine autophosphorylation
CLM73_RS25320	COG1396	sequence-specific DNA binding
CLM73_RS25325	COG0326	Molecular chaperone. Has ATPase activity
CLM73_RS25330	COG2233	PERMEase
CLM73_RS25340	COG0745	RESPONSE REGULATOR receiver
CLM73_RS25460	COG0740	serine-type endopeptidase activity
CLM73_RS25570	COG2200	EAL domain
CLM73_RS25625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLM73_RS25680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM73_RS25685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLM73_RS25695	COG0583	DNA-binding transcription factor activity
CLM73_RS25710	COG0477	Major facilitator Superfamily
CLM73_RS25740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS25745	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS25750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM73_RS25780	COG4638	Rieske (2fe-2S)
CLM73_RS25790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM73_RS25795	COG3246	L-lysine catabolic process to acetate
CLM73_RS25805	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS25870	COG0583	DNA-binding transcription factor activity
CLM73_RS25880	COG1695	Transcriptional regulator
CLM73_RS25895	COG0477	Major facilitator Superfamily
CLM73_RS25910	COG0628	permease
CLM73_RS25915	COG0583	DNA-binding transcription factor activity
CLM73_RS25920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM73_RS25960	COG3829	transcription factor binding
CLM73_RS26055	COG0625	glutathione transferase activity
CLM73_RS26060	COG0077	Prephenate dehydratase
CLM73_RS26060	COG1605	Chorismate mutase
CLM73_RS26070	COG2081	HI0933 family
CLM73_RS26075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM73_RS26095	COG1129	ABC transporter
CLM73_RS26115	COG2207	Transcriptional regulator
CLM73_RS26120	COG4774	siderophore transport
CLM73_RS26145	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS26160	COG1126	abc transporter atp-binding protein
CLM73_RS26165	COG0765	amino acid transport
CLM73_RS26170	COG4597	amino acid ABC transporter
CLM73_RS26175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS26180	COG2884	Cell division ATP-binding protein ftsE
CLM73_RS26185	COG2177	Part of the ABC transporter FtsEX involved in
CLM73_RS26195	COG3712	iron ion homeostasis
CLM73_RS26215	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CLM73_RS26225	COG2186	Transcriptional regulator
CLM73_RS26255	COG0410	ABC transporter
CLM73_RS26260	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS26265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CLM73_RS26275	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLM73_RS26280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLM73_RS26285	COG0583	DNA-binding transcription factor activity
CLM73_RS26290	COG4773	Receptor
CLM73_RS26305	COG3550	peptidyl-serine autophosphorylation
CLM73_RS26315	COG0129	dihydroxy-acid dehydratase activity
CLM73_RS26340	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLM73_RS26345	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CLM73_RS26350	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM73_RS26355	COG2031	fatty acid transporter
CLM73_RS26360	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS26365	COG1414	Transcriptional regulator
CLM73_RS26375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLM73_RS26380	COG4829	muconolactone delta-isomerase
CLM73_RS26390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM73_RS26410	COG0288	reversible hydration of carbon dioxide
CLM73_RS26415	COG1802	Transcriptional regulator
CLM73_RS26420	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS26430	COG0559	Belongs to the binding-protein-dependent transport system permease family
CLM73_RS26450	COG1028	Short-chain dehydrogenase reductase Sdr
CLM73_RS26460	COG1053	succinate dehydrogenase
CLM73_RS26465	COG0625	glutathione transferase activity
CLM73_RS26470	COG2207	Transcriptional regulator
CLM73_RS26475	COG0300	oxidoreductase activity
CLM73_RS26490	COG0583	DNA-binding transcription factor activity
CLM73_RS26520	COG0318	PFAM AMP-dependent synthetase and ligase
CLM73_RS26535	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS26540	COG4948	Mandelate Racemase Muconate Lactonizing
CLM73_RS26555	COG1464	Belongs to the NlpA lipoprotein family
CLM73_RS26570	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CLM73_RS26575	COG2890	protein-(glutamine-N5) methyltransferase activity
CLM73_RS26580	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLM73_RS26605	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CLM73_RS26605	COG3264	Mechanosensitive ion channel
CLM73_RS26610	COG1522	sequence-specific DNA binding
CLM73_RS26620	COG5006	permease, DMT superfamily
CLM73_RS26635	COG3622	Belongs to the hyi family
CLM73_RS26660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLM73_RS26670	COG3842	ATPase activity
CLM73_RS26675	COG1175	transmembrane transport
CLM73_RS26695	COG2186	Transcriptional regulator
CLM73_RS26700	COG3395	kinase activity
CLM73_RS26705	COG2084	Dehydrogenase
CLM73_RS26710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM73_RS26715	COG3622	Belongs to the hyi family
CLM73_RS26720	COG2271	Major facilitator Superfamily
CLM73_RS26725	COG0235	Class ii aldolase
CLM73_RS26745	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CLM73_RS26755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM73_RS26765	COG4774	siderophore transport
CLM73_RS26770	COG1595	DNA-templated transcription, initiation
CLM73_RS26780	COG3712	iron ion homeostasis
CLM73_RS26785	COG1595	DNA-templated transcription, initiation
CLM73_RS26815	COG0583	DNA-binding transcription factor activity
CLM73_RS26825	COG1960	acyl-CoA dehydrogenase activity
CLM73_RS26840	COG3866	Pectate lyase
CLM73_RS26845	COG1560	Kdo2-lipid A biosynthetic process
CLM73_RS26845	COG4783	chaperone-mediated protein folding
CLM73_RS26870	COG0438	transferase activity, transferring glycosyl groups
CLM73_RS26875	COG0457	Tetratricopeptide repeat
CLM73_RS26890	COG0142	geranyltranstransferase activity
CLM73_RS26900	COG1414	Transcriptional regulator
CLM73_RS26905	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CLM73_RS26910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLM73_RS26915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLM73_RS26920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLM73_RS26935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLM73_RS26945	COG3547	Transposase (IS116 IS110 IS902 family)
CLM73_RS26955	COG2186	Transcriptional regulator
CLM73_RS26970	COG0793	Belongs to the peptidase S41A family
CLM73_RS26975	COG4942	peptidase
CLM73_RS26980	COG0588	phosphoglycerate mutase activity
CLM73_RS26985	COG1054	Belongs to the UPF0176 family
CLM73_RS26990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLM73_RS26995	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CLM73_RS27000	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLM73_RS27005	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS27010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CLM73_RS27015	COG1040	competence protein
CLM73_RS27020	COG2226	methyltransferase
CLM73_RS27025	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CLM73_RS27035	COG0569	domain protein
CLM73_RS27040	COG2204	response regulator
CLM73_RS27045	COG5000	phosphorelay sensor kinase activity
CLM73_RS27060	COG1280	lysine exporter protein (LysE YggA)
CLM73_RS27070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLM73_RS27090	COG0546	phosphoglycolate phosphatase activity
CLM73_RS27110	COG0242	peptide deformylase activity
CLM73_RS27115	COG0758	DNA mediated transformation
CLM73_RS27130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM73_RS27135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM73_RS27140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLM73_RS27145	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS27150	COG0071	Belongs to the small heat shock protein (HSP20) family
CLM73_RS27165	COG1238	metal cluster binding
CLM73_RS27170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLM73_RS27175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLM73_RS27195	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLM73_RS27200	COG4988	ABC transporter
CLM73_RS27210	COG1294	oxidase, subunit
CLM73_RS27215	COG1271	oxidase subunit
CLM73_RS27225	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CLM73_RS27235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CLM73_RS27250	COG1137	ATPase activity
CLM73_RS27255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLM73_RS27265	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CLM73_RS27270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM73_RS27285	COG1660	Displays ATPase and GTPase activities
CLM73_RS27290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLM73_RS27295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLM73_RS27310	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CLM73_RS27315	COG2823	Periplasmic or secreted lipoprotein
CLM73_RS27320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM73_RS27325	COG1464	Belongs to the NlpA lipoprotein family
CLM73_RS27330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLM73_RS27340	COG1309	transcriptional regulator
CLM73_RS27345	COG0471	metal ion transport
CLM73_RS27350	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CLM73_RS27360	COG0772	Belongs to the SEDS family
CLM73_RS27365	COG0768	penicillin binding
CLM73_RS27375	COG1792	Involved in formation and maintenance of cell shape
CLM73_RS27380	COG1077	Cell shape determining protein MreB Mrl
CLM73_RS27385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLM73_RS27390	COG0154	amidase activity
CLM73_RS27395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLM73_RS27410	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLM73_RS27415	COG0708	Exodeoxyribonuclease III
CLM73_RS27420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLM73_RS27430	COG0583	DNA-binding transcription factor activity
CLM73_RS27440	COG0583	DNA-binding transcription factor activity
CLM73_RS27465	COG3547	Transposase (IS116 IS110 IS902 family)
CLM73_RS27470	COG1764	response to oxidative stress
CLM73_RS27475	COG1846	Transcriptional regulator
CLM73_RS27530	COG0640	Transcriptional regulator
CLM73_RS27555	COG0297	glycogen (starch) synthase activity
CLM73_RS27565	COG3189	MarR family transcriptional regulator
CLM73_RS27570	COG0351	phosphomethylpyrimidine kinase
CLM73_RS27570	COG0352	thiamine-phosphate diphosphorylase activity
CLM73_RS27570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CLM73_RS27575	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLM73_RS27580	COG0513	Belongs to the DEAD box helicase family
CLM73_RS27590	COG0617	tRNA 3'-terminal CCA addition
CLM73_RS27600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLM73_RS27605	COG2308	Evidence 4 Homologs of previously reported genes of
CLM73_RS27615	COG1305	Transglutaminase-like
CLM73_RS27625	COG1024	Enoyl-CoA hydratase
CLM73_RS27655	COG0673	inositol 2-dehydrogenase activity
CLM73_RS27660	COG1609	Transcriptional regulator
CLM73_RS27685	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLM73_RS27690	COG1950	PFAM Membrane protein of
CLM73_RS27695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CLM73_RS27715	COG0066	3-isopropylmalate dehydratase activity
CLM73_RS27725	COG3181	Tripartite tricarboxylate transporter family receptor
CLM73_RS27730	COG0583	DNA-binding transcription factor activity
CLM73_RS27735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLM73_RS27770	COG0477	Major facilitator Superfamily
CLM73_RS27775	COG0154	amidase activity
CLM73_RS27780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLM73_RS27790	COG1560	Kdo2-lipid A biosynthetic process
CLM73_RS27795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLM73_RS27805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLM73_RS27810	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CLM73_RS27820	COG0803	Belongs to the bacterial solute-binding protein 9 family
CLM73_RS27835	COG0735	belongs to the Fur family
CLM73_RS27840	COG0523	cobalamin synthesis protein
CLM73_RS27850	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CLM73_RS27855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CLM73_RS27865	COG2096	Adenosyltransferase
CLM73_RS27875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CLM73_RS27880	COG1609	Transcriptional regulator
CLM73_RS27890	COG0321	lipoyl(octanoyl) transferase activity
CLM73_RS27895	COG2921	Belongs to the UPF0250 family
CLM73_RS27905	COG1686	Belongs to the peptidase S11 family
CLM73_RS27930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLM73_RS27940	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CLM73_RS27950	COG0859	PFAM glycosyl transferase family 9
CLM73_RS27970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLM73_RS27980	COG1086	Polysaccharide biosynthesis protein
CLM73_RS28000	COG3274	enterobacterial common antigen metabolic process
CLM73_RS28005	COG0438	transferase activity, transferring glycosyl groups
CLM73_RS28010	COG0357	Ribosomal RNA small subunit methyltransferase G
CLM73_RS28025	COG0756	dUTP diphosphatase activity
CLM73_RS28030	COG2814	Major facilitator Superfamily
CLM73_RS28035	COG0697	spore germination
CLM73_RS28055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM73_RS28060	COG3568	Endonuclease Exonuclease Phosphatase
CLM73_RS28065	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLM73_RS28090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLM73_RS28105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM73_RS28110	COG1956	GAF domain-containing protein
CLM73_RS28115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM73_RS28140	COG2186	Transcriptional regulator
CLM73_RS28145	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CLM73_RS28180	COG4948	Mandelate Racemase Muconate Lactonizing
CLM73_RS28185	COG0583	DNA-binding transcription factor activity
CLM73_RS28190	COG0463	Glycosyl transferase, family 2
CLM73_RS28215	COG2814	Major facilitator Superfamily
CLM73_RS28230	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CLM73_RS28235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLM73_RS28240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLM73_RS28250	COG1965	Belongs to the frataxin family
CLM73_RS28260	COG0019	diaminopimelate decarboxylase activity
CLM73_RS28265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLM73_RS28270	COG1333	cytochrome c biogenesis protein
CLM73_RS28280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLM73_RS28295	COG4232	protein-disulfide reductase activity
CLM73_RS28300	COG1324	tolerance protein
CLM73_RS28310	COG0203	ribosomal protein L17
CLM73_RS28315	COG0202	RNA polymerase activity
CLM73_RS28320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLM73_RS28325	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLM73_RS28330	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLM73_RS28335	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLM73_RS28340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLM73_RS28345	COG0201	protein transport
CLM73_RS28350	COG0200	Binds to the 23S rRNA
CLM73_RS28355	COG1841	ribosomal large subunit assembly
CLM73_RS28360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLM73_RS28365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLM73_RS28370	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLM73_RS28375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLM73_RS28380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLM73_RS28385	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLM73_RS28390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLM73_RS28395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLM73_RS28415	COG2207	Transcriptional regulator
CLM73_RS28430	COG0411	ABC transporter
CLM73_RS28455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLM73_RS28460	COG0255	Belongs to the universal ribosomal protein uL29 family
CLM73_RS28465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLM73_RS28470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLM73_RS28475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLM73_RS28480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLM73_RS28485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLM73_RS28490	COG0089	rRNA binding
CLM73_RS28500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLM73_RS28505	COG0051	transcription antitermination factor activity, RNA binding
CLM73_RS28510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLM73_RS28515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLM73_RS28520	COG0049	tRNA binding
CLM73_RS28525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLM73_RS28530	COG0745	RESPONSE REGULATOR receiver
CLM73_RS28560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLM73_RS28565	COG0085	RNA polymerase activity
CLM73_RS28570	COG0222	ribosome binding
CLM73_RS28575	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLM73_RS28580	COG0081	regulation of translation
CLM73_RS28585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLM73_RS28605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLM73_RS28630	COG1012	belongs to the aldehyde dehydrogenase family
CLM73_RS28660	COG0583	DNA-binding transcription factor activity
CLM73_RS28665	COG0252	asparaginase activity
CLM73_RS28670	COG1475	DNA binding
CLM73_RS28680	COG1192	Involved in chromosome partitioning
CLM73_RS28685	COG0357	Ribosomal RNA small subunit methyltransferase G
CLM73_RS28690	COG0445	tRNA wobble uridine modification
CLM73_RS28695	COG1278	Cold shock
CLM73_RS28700	COG3180	Ammonia monooxygenase
CLM73_RS28705	COG0436	Aminotransferase
CLM73_RS28725	COG5002	protein histidine kinase activity
CLM73_RS28725	COG3850	Histidine kinase
CLM73_RS28755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLM73_RS28765	COG0601	transmembrane transport
CLM73_RS28770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM73_RS28775	COG0444	Belongs to the ABC transporter superfamily
CLM73_RS28780	COG4608	Belongs to the ABC transporter superfamily
CLM73_RS28785	COG1473	amidohydrolase
CLM73_RS28790	COG2175	clavaminate synthase activity
CLM73_RS28800	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CLM73_RS28810	COG0753	catalase activity
CLM73_RS28815	COG0706	membrane insertase activity
CLM73_RS28820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CLM73_RS28825	COG0594	ribonuclease P activity
CLM73_RS28830	COG0230	Belongs to the bacterial ribosomal protein bL34 family