locus-tag	class	description
AXYL_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AXYL_RS00015	COG0592	DNA-directed DNA polymerase activity
AXYL_RS00040	COG0765	amino acid transport
AXYL_RS00045	COG0765	amino acid transport
AXYL_RS00050	COG1126	abc transporter atp-binding protein
AXYL_RS00060	COG0436	Aminotransferase
AXYL_RS00070	COG0583	DNA-binding transcription factor activity
AXYL_RS00085	COG1741	Belongs to the pirin family
AXYL_RS00095	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AXYL_RS00120	COG0154	amidase activity
AXYL_RS00125	COG1917	Cupin 2, conserved barrel domain protein
AXYL_RS00150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_RS00155	COG0583	DNA-binding transcription factor activity
AXYL_RS00160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS00165	COG0765	amino acid transport
AXYL_RS00170	COG0765	amino acid transport
AXYL_RS00175	COG1126	abc transporter atp-binding protein
AXYL_RS00200	COG1304	FMN binding
AXYL_RS00215	COG0402	S-adenosylhomocysteine deaminase activity
AXYL_RS00225	COG4603	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS00230	COG3845	ABC transporter
AXYL_RS00235	COG1744	ABC transporter substrate-binding protein PnrA-like
AXYL_RS00245	COG0586	Pfam SNARE associated Golgi protein
AXYL_RS00250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXYL_RS00265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_RS00280	COG2814	Major facilitator Superfamily
AXYL_RS00295	COG3781	membrane
AXYL_RS00300	COG1522	sequence-specific DNA binding
AXYL_RS00305	COG0028	Belongs to the TPP enzyme family
AXYL_RS00310	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS00315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS00320	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXYL_RS00330	COG0551	DNA topoisomerase type I activity
AXYL_RS00330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXYL_RS00340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXYL_RS00345	COG2922	Belongs to the Smg family
AXYL_RS00355	COG2358	TRAP transporter, solute receptor (TAXI family
AXYL_RS00395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXYL_RS00425	COG0110	maltose O-acetyltransferase activity
AXYL_RS00430	COG0596	Alpha beta hydrolase
AXYL_RS00460	COG3339	Conserved Protein
AXYL_RS00480	COG2957	Belongs to the agmatine deiminase family
AXYL_RS00485	COG0583	DNA-binding transcription factor activity
AXYL_RS00520	COG0583	DNA-binding transcription factor activity
AXYL_RS00525	COG0492	ferredoxin-NADP+ reductase activity
AXYL_RS00560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXYL_RS00565	COG0183	Belongs to the thiolase family
AXYL_RS00570	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AXYL_RS00575	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS00580	COG1473	amidohydrolase
AXYL_RS00585	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS00590	COG1742	UPF0060 membrane protein
AXYL_RS00610	COG0778	Nitroreductase
AXYL_RS00630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXYL_RS00655	COG0395	ABC-type sugar transport system, permease component
AXYL_RS00660	COG1175	transmembrane transport
AXYL_RS00665	COG1653	transport
AXYL_RS00670	COG3842	ATPase activity
AXYL_RS00675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXYL_RS00680	COG1609	Transcriptional regulator
AXYL_RS00685	COG0154	amidase activity
AXYL_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXYL_RS00710	COG0583	DNA-binding transcription factor activity
AXYL_RS00730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXYL_RS00735	COG1280	lysine exporter protein (LysE YggA)
AXYL_RS00740	COG0513	Belongs to the DEAD box helicase family
AXYL_RS00745	COG5339	Protein conserved in bacteria
AXYL_RS00755	COG4172	Belongs to the ABC transporter superfamily
AXYL_RS00760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS00765	COG0601	transmembrane transport
AXYL_RS00770	COG0747	negative chemotaxis
AXYL_RS00775	COG1160	GTP binding
AXYL_RS00785	COG3708	Transcriptional regulator
AXYL_RS00785	COG2207	Transcriptional regulator
AXYL_RS00795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXYL_RS00805	COG0583	DNA-binding transcription factor activity
AXYL_RS00830	COG2969	positive regulation of protein catabolic process
AXYL_RS00835	COG0625	glutathione transferase activity
AXYL_RS00840	COG2857	Cytochrome c1
AXYL_RS00845	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AXYL_RS00850	COG0723	plastoquinol--plastocyanin reductase activity
AXYL_RS00855	COG1970	mechanosensitive ion channel activity
AXYL_RS00860	COG0235	Class ii aldolase
AXYL_RS00870	COG0477	Major facilitator Superfamily
AXYL_RS00880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXYL_RS00885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXYL_RS00900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXYL_RS00905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXYL_RS00910	COG0537	adenosine 5'-monophosphoramidase activity
AXYL_RS00915	COG0140	phosphoribosyl-ATP diphosphatase activity
AXYL_RS00925	COG0107	imidazoleglycerol-phosphate synthase activity
AXYL_RS00930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AXYL_RS00935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXYL_RS00940	COG0131	Imidazoleglycerol-phosphate dehydratase
AXYL_RS00945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXYL_RS00950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AXYL_RS00955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AXYL_RS00960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXYL_RS00970	COG0842	Transport permease protein
AXYL_RS00975	COG1131	(ABC) transporter
AXYL_RS00985	COG2853	Lipoprotein
AXYL_RS00990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXYL_RS00995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXYL_RS01000	COG1127	ABC transporter
AXYL_RS01015	COG0477	Major facilitator Superfamily
AXYL_RS01020	COG0583	DNA-binding transcription factor activity
AXYL_RS01035	COG0069	glutamate synthase activity
AXYL_RS01035	COG0070	glutamate synthase
AXYL_RS01035	COG0067	glutamate synthase
AXYL_RS01060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXYL_RS01080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXYL_RS01115	COG1612	heme a metabolic process
AXYL_RS01125	COG1999	signal sequence binding
AXYL_RS01145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXYL_RS01150	COG2814	Major facilitator Superfamily
AXYL_RS01160	COG0438	transferase activity, transferring glycosyl groups
AXYL_RS01165	COG1522	sequence-specific DNA binding
AXYL_RS01180	COG0457	Tetratricopeptide repeat
AXYL_RS01185	COG0438	transferase activity, transferring glycosyl groups
AXYL_RS01210	COG1560	Kdo2-lipid A biosynthetic process
AXYL_RS01210	COG4783	chaperone-mediated protein folding
AXYL_RS01225	COG2814	Major facilitator Superfamily
AXYL_RS01230	COG1764	response to oxidative stress
AXYL_RS01245	COG3246	L-lysine catabolic process to acetate
AXYL_RS01255	COG0861	Integral membrane protein TerC family
AXYL_RS01270	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS01275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_RS01280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS01305	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS01305	COG2030	dehydratase
AXYL_RS01315	COG1414	Transcriptional regulator
AXYL_RS01330	COG1956	GAF domain-containing protein
AXYL_RS01340	COG0656	L-ascorbic acid biosynthetic process
AXYL_RS01345	COG0583	DNA-binding transcription factor activity
AXYL_RS01350	COG2423	ornithine cyclodeaminase activity
AXYL_RS01360	COG1522	sequence-specific DNA binding
AXYL_RS01365	COG2423	ornithine cyclodeaminase activity
AXYL_RS01375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AXYL_RS01380	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AXYL_RS01395	COG0737	Belongs to the 5'-nucleotidase family
AXYL_RS01425	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AXYL_RS01435	COG1228	amidohydrolase
AXYL_RS01445	COG2814	Major facilitator Superfamily
AXYL_RS01450	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS01500	COG1802	Transcriptional regulator
AXYL_RS01510	COG3069	C4-dicarboxylate transmembrane transporter activity
AXYL_RS01525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_RS01525	COG0543	2 iron, 2 sulfur cluster binding
AXYL_RS01535	COG0431	NADPH-dependent FMN reductase
AXYL_RS01540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS01545	COG1116	anion transmembrane transporter activity
AXYL_RS01550	COG3585	molybdate ion transport
AXYL_RS01555	COG3064	Membrane
AXYL_RS01580	COG1607	acyl-coa hydrolase
AXYL_RS01590	COG0243	molybdopterin cofactor binding
AXYL_RS01590	COG3383	formate dehydrogenase (NAD+) activity
AXYL_RS01595	COG3383	formate dehydrogenase (NAD+) activity
AXYL_RS01595	COG0243	molybdopterin cofactor binding
AXYL_RS01600	COG0437	4 iron, 4 sulfur cluster binding
AXYL_RS01605	COG2864	formate dehydrogenase
AXYL_RS01615	COG1921	L-seryl-tRNASec selenium transferase activity
AXYL_RS01620	COG3276	selenocysteine insertion sequence binding
AXYL_RS01635	COG1305	Transglutaminase-like
AXYL_RS01640	COG0709	Synthesizes selenophosphate from selenide and ATP
AXYL_RS01670	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS01675	COG3284	Transcriptional regulator
AXYL_RS01680	COG0134	indole-3-glycerol-phosphate synthase activity
AXYL_RS01690	COG0512	Glutamine amidotransferase of anthranilate synthase
AXYL_RS01700	COG0546	phosphoglycolate phosphatase activity
AXYL_RS01705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXYL_RS01710	COG2967	ApaG domain
AXYL_RS01715	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AXYL_RS01720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_RS01730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_RS01735	COG0037	tRNA processing
AXYL_RS01750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXYL_RS01755	COG0583	DNA-binding transcription factor activity
AXYL_RS01760	COG0683	leucine binding
AXYL_RS01785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXYL_RS01810	COG3473	Maleate cis-trans isomerase
AXYL_RS01820	COG3328	transposase activity
AXYL_RS01825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXYL_RS01830	COG1024	Enoyl-CoA hydratase
AXYL_RS01845	COG0356	it plays a direct role in the translocation of protons across the membrane
AXYL_RS01860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AXYL_RS01865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AXYL_RS01870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AXYL_RS01880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AXYL_RS01890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AXYL_RS01895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXYL_RS01900	COG0210	DNA helicase
AXYL_RS01905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXYL_RS01915	COG2171	N-acyltransferase activity
AXYL_RS01925	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXYL_RS01935	COG4608	Belongs to the ABC transporter superfamily
AXYL_RS01940	COG0444	Belongs to the ABC transporter superfamily
AXYL_RS01950	COG0601	transmembrane transport
AXYL_RS01955	COG4166	transmembrane transport
AXYL_RS01965	COG0583	DNA-binding transcription factor activity
AXYL_RS01970	COG0747	negative chemotaxis
AXYL_RS01980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXYL_RS01985	COG1024	Enoyl-CoA hydratase
AXYL_RS01990	COG1024	Enoyl-CoA hydratase
AXYL_RS02000	COG1309	transcriptional regulator
AXYL_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS02015	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS02030	COG0523	cobalamin synthesis protein
AXYL_RS02040	COG0583	DNA-binding transcription factor activity
AXYL_RS02060	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS02075	COG4774	siderophore transport
AXYL_RS02080	COG3712	iron ion homeostasis
AXYL_RS02085	COG1595	DNA-templated transcription, initiation
AXYL_RS02095	COG2188	Transcriptional regulator
AXYL_RS02100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AXYL_RS02105	COG1070	Carbohydrate kinase
AXYL_RS02120	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS02125	COG0667	Aldo Keto reductase
AXYL_RS02135	COG0633	Ferredoxin
AXYL_RS02140	COG0784	Response regulator, receiver
AXYL_RS02140	COG2205	protein histidine kinase activity
AXYL_RS02145	COG2197	response regulator
AXYL_RS02195	COG1764	response to oxidative stress
AXYL_RS02200	COG0583	DNA-binding transcription factor activity
AXYL_RS02210	COG1595	DNA-templated transcription, initiation
AXYL_RS02230	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS02235	COG0583	DNA-binding transcription factor activity
AXYL_RS02255	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_RS02275	COG1129	ABC transporter
AXYL_RS02285	COG1802	Transcriptional regulator
AXYL_RS02295	COG0583	DNA-binding transcription factor activity
AXYL_RS02315	COG2918	glutathione biosynthetic process
AXYL_RS02330	COG2197	response regulator
AXYL_RS02340	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_RS02345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_RS02355	COG2721	sulfolactate sulfo-lyase activity
AXYL_RS02360	COG2721	sulfolactate sulfo-lyase activity
AXYL_RS02365	COG2188	Transcriptional regulator
AXYL_RS02370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXYL_RS02375	COG2813	Specifically methylates the guanine in position
AXYL_RS02375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXYL_RS02380	COG2223	nitrite transmembrane transporter activity
AXYL_RS02390	COG2860	membrane
AXYL_RS02395	COG1802	Transcriptional regulator
AXYL_RS02405	COG1984	allophanate hydrolase subunit 2
AXYL_RS02410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AXYL_RS02430	COG4774	siderophore transport
AXYL_RS02445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_RS02455	COG0642	Histidine kinase
AXYL_RS02470	COG0745	RESPONSE REGULATOR receiver
AXYL_RS02475	COG2226	methyltransferase
AXYL_RS02490	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AXYL_RS02500	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXYL_RS02510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXYL_RS02515	COG0351	phosphomethylpyrimidine kinase
AXYL_RS02520	COG2022	thiamine diphosphate biosynthetic process
AXYL_RS02525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXYL_RS02530	COG4771	TonB-dependent receptor
AXYL_RS02545	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS02575	COG0583	DNA-binding transcription factor activity
AXYL_RS02590	COG0625	glutathione transferase activity
AXYL_RS02595	COG1053	succinate dehydrogenase
AXYL_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS02605	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS02635	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS02640	COG1802	Transcriptional regulator
AXYL_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS02650	COG0288	reversible hydration of carbon dioxide
AXYL_RS02670	COG2226	methyltransferase
AXYL_RS02680	COG1802	Transcriptional regulator
AXYL_RS02685	COG0028	Belongs to the TPP enzyme family
AXYL_RS02700	COG1194	a g-specific adenine glycosylase
AXYL_RS02715	COG0477	Major facilitator Superfamily
AXYL_RS02725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AXYL_RS02730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AXYL_RS02750	COG0237	dephospho-CoA kinase activity
AXYL_RS02755	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AXYL_RS02770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_RS02785	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS02790	COG0583	DNA-binding transcription factor activity
AXYL_RS02795	COG0154	amidase activity
AXYL_RS02800	COG0683	leucine binding
AXYL_RS02845	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AXYL_RS02905	COG2199	diguanylate cyclase activity
AXYL_RS02905	COG2200	EAL domain
AXYL_RS02905	COG2202	Pas domain
AXYL_RS02915	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS02920	COG1024	Enoyl-CoA hydratase
AXYL_RS02960	COG4638	Rieske (2fe-2S)
AXYL_RS02965	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXYL_RS02970	COG1335	isochorismatase
AXYL_RS02985	COG0741	lytic transglycosylase activity
AXYL_RS02990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AXYL_RS02995	COG0352	thiamine-phosphate diphosphorylase activity
AXYL_RS03000	COG0352	thiamine-phosphate diphosphorylase activity
AXYL_RS03000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXYL_RS03000	COG0351	phosphomethylpyrimidine kinase
AXYL_RS03010	COG1678	Uncharacterized ACR, COG1678
AXYL_RS03015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AXYL_RS03020	COG0540	Belongs to the ATCase OTCase family
AXYL_RS03035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXYL_RS03045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXYL_RS03050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXYL_RS03065	COG1175	transmembrane transport
AXYL_RS03085	COG0557	exoribonuclease II activity
AXYL_RS03090	COG3150	esterase
AXYL_RS03095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXYL_RS03100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_RS03105	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AXYL_RS03110	COG0511	ligase activity, forming carbon-carbon bonds
AXYL_RS03115	COG0439	Biotin carboxylase
AXYL_RS03120	COG2264	protein methyltransferase activity
AXYL_RS03130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXYL_RS03130	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AXYL_RS03155	COG1696	Membrane protein involved in D-alanine export
AXYL_RS03160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXYL_RS03165	COG0762	integral membrane protein
AXYL_RS03190	COG1522	sequence-specific DNA binding
AXYL_RS03195	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS03205	COG0583	DNA-binding transcription factor activity
AXYL_RS03220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXYL_RS03225	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_RS03225	COG1042	CoA-binding domain protein
AXYL_RS03225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_RS03230	COG1335	isochorismatase
AXYL_RS03235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS03240	COG1116	anion transmembrane transporter activity
AXYL_RS03255	COG3028	Belongs to the UPF0307 family
AXYL_RS03260	COG0312	modulator of DNA gyrase
AXYL_RS03265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXYL_RS03275	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS03280	COG4177	L-phenylalanine transmembrane transporter activity
AXYL_RS03295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AXYL_RS03300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AXYL_RS03305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AXYL_RS03315	COG0316	Belongs to the HesB IscA family
AXYL_RS03320	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AXYL_RS03330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXYL_RS03335	COG1881	PFAM PEBP family protein
AXYL_RS03345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AXYL_RS03350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AXYL_RS03355	COG2207	Transcriptional regulator
AXYL_RS03365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXYL_RS03365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXYL_RS03380	COG2766	serine protein kinase
AXYL_RS03385	COG2718	Belongs to the UPF0229 family
AXYL_RS03390	COG2719	SpoVR family
AXYL_RS03410	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS03435	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS03460	COG3608	succinylglutamate desuccinylase aspartoacylase
AXYL_RS03480	COG0741	lytic transglycosylase activity
AXYL_RS03480	COG1388	LysM domain
AXYL_RS03485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXYL_RS03490	COG2226	methyltransferase
AXYL_RS03495	COG0328	RNA-DNA hybrid ribonuclease activity
AXYL_RS03500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS03505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_RS03525	COG1671	Belongs to the UPF0178 family
AXYL_RS03540	COG0786	glutamate:sodium symporter activity
AXYL_RS03550	COG0463	Glycosyl transferase, family 2
AXYL_RS03555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AXYL_RS03565	COG0583	DNA-binding transcription factor activity
AXYL_RS03600	COG1129	ABC transporter
AXYL_RS03605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_RS03615	COG0583	DNA-binding transcription factor activity
AXYL_RS03620	COG1380	Effector of murein hydrolase LrgA
AXYL_RS03625	COG1346	cytolysis
AXYL_RS03635	COG0697	spore germination
AXYL_RS03640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_RS03655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXYL_RS03665	COG1522	sequence-specific DNA binding
AXYL_RS03670	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_RS03670	COG0596	Alpha beta hydrolase
AXYL_RS03680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AXYL_RS03685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_RS03700	COG0823	Involved in the tonB-independent uptake of proteins
AXYL_RS03710	COG0848	biopolymer transport protein
AXYL_RS03715	COG0811	peptide transport
AXYL_RS03720	COG0824	Thioesterase
AXYL_RS03755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_RS03770	COG2084	Dehydrogenase
AXYL_RS03810	COG0129	dihydroxy-acid dehydratase activity
AXYL_RS03815	COG4654	Cytochrome c, class I
AXYL_RS03820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXYL_RS03830	COG1522	sequence-specific DNA binding
AXYL_RS03875	COG1473	amidohydrolase
AXYL_RS03880	COG0418	dihydroorotase activity
AXYL_RS03885	COG0488	(ABC) transporter
AXYL_RS03890	COG2001	Belongs to the MraZ family
AXYL_RS03895	COG0275	rRNA processing
AXYL_RS03900	COG3116	cell division
AXYL_RS03910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXYL_RS03915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXYL_RS03920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AXYL_RS03930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AXYL_RS03935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXYL_RS03940	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXYL_RS03945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AXYL_RS03955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXYL_RS03960	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AXYL_RS03970	COG0739	heme binding
AXYL_RS03975	COG0653	protein targeting
AXYL_RS03985	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AXYL_RS03985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_RS03995	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS04000	COG0028	Belongs to the TPP enzyme family
AXYL_RS04005	COG0300	oxidoreductase activity
AXYL_RS04010	COG1522	sequence-specific DNA binding
AXYL_RS04025	COG2239	Acts as a magnesium transporter
AXYL_RS04035	COG2855	membrane
AXYL_RS04045	COG1473	amidohydrolase
AXYL_RS04050	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS04060	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AXYL_RS04060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS04065	COG1501	Belongs to the glycosyl hydrolase 31 family
AXYL_RS04070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXYL_RS04075	COG2011	ABC-type metal ion transport system permease component
AXYL_RS04090	COG0840	transmembrane signaling receptor activity
AXYL_RS04095	COG3706	GGDEF domain
AXYL_RS04150	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS04175	COG0735	belongs to the Fur family
AXYL_RS04195	COG2818	Glycosylase
AXYL_RS04200	COG1368	sulfuric ester hydrolase activity
AXYL_RS04205	COG2982	Protein involved in outer membrane biogenesis
AXYL_RS04220	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS04235	COG3712	iron ion homeostasis
AXYL_RS04240	COG4774	siderophore transport
AXYL_RS04250	COG1522	sequence-specific DNA binding
AXYL_RS04260	COG0436	Aminotransferase
AXYL_RS04280	COG2154	pterin-4-alpha-carbinolamine dehydratase
AXYL_RS04295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_RS04305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXYL_RS04320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_RS04325	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXYL_RS04330	COG2801	Transposase and inactivated derivatives
AXYL_RS04340	COG1929	Belongs to the glycerate kinase type-1 family
AXYL_RS04345	COG0469	pyruvate kinase activity
AXYL_RS04350	COG0700	Nucleoside recognition
AXYL_RS04355	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS04360	COG0242	peptide deformylase activity
AXYL_RS04370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXYL_RS04380	COG0204	Acyl-transferase
AXYL_RS04385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AXYL_RS04390	COG0751	glycine-tRNA ligase activity
AXYL_RS04395	COG0752	glycyl-tRNA synthetase alpha subunit
AXYL_RS04400	COG1024	Enoyl-CoA hydratase
AXYL_RS04410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS04415	COG2030	dehydratase
AXYL_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS04425	COG0583	DNA-binding transcription factor activity
AXYL_RS04445	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS04450	COG0183	Belongs to the thiolase family
AXYL_RS04460	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS04470	COG1024	Enoyl-CoA hydratase
AXYL_RS04475	COG0583	DNA-binding transcription factor activity
AXYL_RS04480	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AXYL_RS04485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS04490	COG2301	Belongs to the HpcH HpaI aldolase family
AXYL_RS04495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXYL_RS04505	COG0617	tRNA 3'-terminal CCA addition
AXYL_RS04520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AXYL_RS04525	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AXYL_RS04530	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AXYL_RS04535	COG0586	Pfam SNARE associated Golgi protein
AXYL_RS04540	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXYL_RS04545	COG0802	atpase or kinase
AXYL_RS04550	COG0114	fumarate hydratase activity
AXYL_RS04560	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS04570	COG0405	Gamma-glutamyltransferase
AXYL_RS04575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS04580	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS04585	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS04590	COG0583	DNA-binding transcription factor activity
AXYL_RS04595	COG0659	secondary active sulfate transmembrane transporter activity
AXYL_RS04605	COG0579	oxidoreductase
AXYL_RS04615	COG0259	pyridoxamine-phosphate oxidase activity
AXYL_RS04630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS04635	COG1136	(ABC) transporter
AXYL_RS04635	COG0577	efflux transmembrane transporter activity
AXYL_RS04640	COG1538	Outer membrane efflux protein
AXYL_RS04660	COG1024	Enoyl-CoA hydratase
AXYL_RS04665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AXYL_RS04700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXYL_RS04725	COG1216	Glycosyl transferase, family 2
AXYL_RS04725	COG0463	Glycosyl transferase, family 2
AXYL_RS04750	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS04755	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AXYL_RS04780	COG4638	Rieske (2fe-2S)
AXYL_RS04805	COG0747	negative chemotaxis
AXYL_RS04810	COG0601	transmembrane transport
AXYL_RS04815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS04820	COG0444	Belongs to the ABC transporter superfamily
AXYL_RS04825	COG4608	Belongs to the ABC transporter superfamily
AXYL_RS04845	COG0488	(ABC) transporter
AXYL_RS04860	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AXYL_RS04865	COG2894	cell division
AXYL_RS04870	COG0850	regulation of cytokinetic process
AXYL_RS04875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXYL_RS04880	COG1271	oxidase subunit
AXYL_RS04890	COG0514	ATP-dependent DNA helicase (RecQ)
AXYL_RS04910	COG2255	four-way junction helicase activity
AXYL_RS04920	COG1090	epimerase
AXYL_RS04925	COG0632	four-way junction helicase activity
AXYL_RS04930	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AXYL_RS04950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_RS04960	COG0006	proline dipeptidase activity
AXYL_RS04980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXYL_RS04985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_RS05000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS05005	COG1113	amino acid transport
AXYL_RS05015	COG4783	chaperone-mediated protein folding
AXYL_RS05020	COG0429	hydrolase of the alpha beta-hydrolase fold
AXYL_RS05050	COG0513	Belongs to the DEAD box helicase family
AXYL_RS05065	COG1546	Belongs to the CinA family
AXYL_RS05065	COG1058	Belongs to the CinA family
AXYL_RS05070	COG1414	Transcriptional regulator
AXYL_RS05085	COG0167	dihydroorotate dehydrogenase activity
AXYL_RS05090	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AXYL_RS05095	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AXYL_RS05190	COG0784	Response regulator, receiver
AXYL_RS05190	COG2205	protein histidine kinase activity
AXYL_RS05200	COG2200	EAL domain
AXYL_RS05200	COG2199	diguanylate cyclase activity
AXYL_RS05200	COG2202	Pas domain
AXYL_RS05205	COG0784	Response regulator, receiver
AXYL_RS05205	COG2205	protein histidine kinase activity
AXYL_RS05265	COG0629	single-stranded DNA binding
AXYL_RS05270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXYL_RS05275	COG0270	DNA (cytosine-5-)-methyltransferase activity
AXYL_RS05315	COG0789	Transcriptional regulator
AXYL_RS05410	COG0431	NADPH-dependent FMN reductase
AXYL_RS05415	COG1393	Belongs to the ArsC family
AXYL_RS05420	COG0798	PFAM Bile acid sodium symporter
AXYL_RS05520	COG2003	Belongs to the UPF0758 family
AXYL_RS05575	COG5002	protein histidine kinase activity
AXYL_RS05580	COG0745	RESPONSE REGULATOR receiver
AXYL_RS05585	COG2132	Multicopper oxidase
AXYL_RS05605	COG2217	Heavy metal translocating P-type atpase
AXYL_RS05625	COG0583	DNA-binding transcription factor activity
AXYL_RS05645	COG3039	Transposase
AXYL_RS05660	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_RS05670	COG0582	viral genome integration into host DNA
AXYL_RS05695	COG1053	succinate dehydrogenase
AXYL_RS05705	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AXYL_RS05735	COG0583	DNA-binding transcription factor activity
AXYL_RS05740	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS05750	COG0753	catalase activity
AXYL_RS05780	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXYL_RS05785	COG0735	belongs to the Fur family
AXYL_RS05790	COG0497	DNA recombination
AXYL_RS05800	COG1420	regulation of RNA biosynthetic process
AXYL_RS05805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AXYL_RS05815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AXYL_RS05825	COG0443	Heat shock 70 kDa protein
AXYL_RS05830	COG0484	heat shock protein binding
AXYL_RS05840	COG0612	Peptidase, M16
AXYL_RS05845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_RS05865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXYL_RS05895	COG0840	transmembrane signaling receptor activity
AXYL_RS05900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_RS05915	COG0745	RESPONSE REGULATOR receiver
AXYL_RS05920	COG2205	protein histidine kinase activity
AXYL_RS05925	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AXYL_RS05930	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AXYL_RS05935	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AXYL_RS05950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXYL_RS05970	COG1193	negative regulation of DNA recombination
AXYL_RS05975	COG0492	ferredoxin-NADP+ reductase activity
AXYL_RS05980	COG1674	ftsk spoiiie
AXYL_RS05985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AXYL_RS05995	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_RS06000	COG1737	Transcriptional regulator
AXYL_RS06020	COG0601	transmembrane transport
AXYL_RS06035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXYL_RS06040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXYL_RS06045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AXYL_RS06085	COG4948	Mandelate Racemase Muconate Lactonizing
AXYL_RS06095	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AXYL_RS06110	COG0477	Major facilitator Superfamily
AXYL_RS06115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXYL_RS06120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_RS06135	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS06140	COG3022	response to hydroperoxide
AXYL_RS06145	COG1289	transmembrane transporter activity
AXYL_RS06150	COG0028	Belongs to the TPP enzyme family
AXYL_RS06155	COG0440	acetolactate synthase activity
AXYL_RS06160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AXYL_RS06165	COG1183	phosphatidylcholine synthase activity
AXYL_RS06175	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AXYL_RS06180	COG1185	polyribonucleotide nucleotidyltransferase activity
AXYL_RS06190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXYL_RS06210	COG0583	DNA-binding transcription factor activity
AXYL_RS06230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS06240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_RS06260	COG0604	alcohol dehydrogenase
AXYL_RS06260	COG3321	synthase
AXYL_RS06265	COG0149	triose-phosphate isomerase activity
AXYL_RS06270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXYL_RS06275	COG1737	Transcriptional regulator
AXYL_RS06280	COG0647	UMP catabolic process
AXYL_RS06290	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXYL_RS06310	COG0583	DNA-binding transcription factor activity
AXYL_RS06315	COG5383	Protein conserved in bacteria
AXYL_RS06325	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS06335	COG2072	flavoprotein involved in K transport
AXYL_RS06340	COG3842	ATPase activity
AXYL_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS06345	COG0604	alcohol dehydrogenase
AXYL_RS06345	COG3321	synthase
AXYL_RS06355	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AXYL_RS06360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_RS06365	COG1177	transmembrane transport
AXYL_RS06370	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_RS06380	COG1126	abc transporter atp-binding protein
AXYL_RS06390	COG4215	(ABC) transporter
AXYL_RS06405	COG0251	oxidation-reduction process
AXYL_RS06430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AXYL_RS06455	COG1024	Enoyl-CoA hydratase
AXYL_RS06470	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS06475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS06485	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_RS06490	COG4608	Belongs to the ABC transporter superfamily
AXYL_RS06495	COG0444	Belongs to the ABC transporter superfamily
AXYL_RS06500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS06505	COG0601	transmembrane transport
AXYL_RS06510	COG0747	negative chemotaxis
AXYL_RS06520	COG0251	oxidation-reduction process
AXYL_RS06530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_RS06530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_RS06555	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AXYL_RS06570	COG1595	DNA-templated transcription, initiation
AXYL_RS06610	COG1971	Probably functions as a manganese efflux pump
AXYL_RS06635	COG1116	anion transmembrane transporter activity
AXYL_RS06650	COG0583	DNA-binding transcription factor activity
AXYL_RS06655	COG3048	D-serine ammonia-lyase activity
AXYL_RS06660	COG2271	Major facilitator Superfamily
AXYL_RS06695	COG0698	ribose 5-phosphate isomerase
AXYL_RS06705	COG0596	Alpha beta hydrolase
AXYL_RS06710	COG2203	Gaf domain
AXYL_RS06710	COG3706	GGDEF domain
AXYL_RS06710	COG4251	negative regulation of phosphorylation
AXYL_RS06710	COG5001	Diguanylate cyclase
AXYL_RS06720	COG0697	spore germination
AXYL_RS06725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_RS06730	COG4774	siderophore transport
AXYL_RS06735	COG3712	iron ion homeostasis
AXYL_RS06740	COG1595	DNA-templated transcription, initiation
AXYL_RS06760	COG1629	transport
AXYL_RS06760	COG4206	TonB-dependent receptor
AXYL_RS06770	COG2832	Protein of unknown function (DUF454)
AXYL_RS06815	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS06845	COG0642	Histidine kinase
AXYL_RS06855	COG2851	Citrate transporter
AXYL_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS06880	COG3119	arylsulfatase activity
AXYL_RS06890	COG0601	transmembrane transport
AXYL_RS06895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS06900	COG4172	Belongs to the ABC transporter superfamily
AXYL_RS06915	COG0583	DNA-binding transcription factor activity
AXYL_RS06920	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS06925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS06930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS06940	COG1609	Transcriptional regulator
AXYL_RS06950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AXYL_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS06965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS06970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS06985	COG0022	dehydrogenase e1 component
AXYL_RS06985	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_RS06995	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_RS07005	COG1278	Cold shock
AXYL_RS07015	COG3604	Transcriptional regulator
AXYL_RS07020	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AXYL_RS07035	COG2354	Protein conserved in bacteria
AXYL_RS07065	COG0747	negative chemotaxis
AXYL_RS07070	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS07090	COG3328	transposase activity
AXYL_RS07130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_RS07140	COG1309	transcriptional regulator
AXYL_RS07150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXYL_RS07155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS07160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_RS07180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_RS07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS07190	COG1309	transcriptional regulator
AXYL_RS07215	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXYL_RS07240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_RS07245	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXYL_RS07250	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXYL_RS07255	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXYL_RS07260	COG0649	NAD binding
AXYL_RS07265	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AXYL_RS07275	COG1034	ATP synthesis coupled electron transport
AXYL_RS07280	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AXYL_RS07285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXYL_RS07295	COG0713	ATP synthesis coupled electron transport
AXYL_RS07310	COG1007	ATP synthesis coupled electron transport
AXYL_RS07320	COG4774	siderophore transport
AXYL_RS07325	COG0560	Phosphoserine phosphatase
AXYL_RS07330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXYL_RS07335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AXYL_RS07340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AXYL_RS07350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXYL_RS07355	COG0450	alkyl hydroperoxide reductase
AXYL_RS07370	COG1214	PFAM Peptidase M22, glycoprotease
AXYL_RS07375	COG1573	uracil-dna glycosylase
AXYL_RS07380	COG0477	Major facilitator Superfamily
AXYL_RS07385	COG1196	nuclear chromosome segregation
AXYL_RS07395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AXYL_RS07400	COG1414	Transcriptional regulator
AXYL_RS07415	COG2175	clavaminate synthase activity
AXYL_RS07420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXYL_RS07425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_RS07430	COG2917	probably involved in intracellular septation
AXYL_RS07435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXYL_RS07440	COG1122	ATPase activity
AXYL_RS07445	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AXYL_RS07450	COG1268	BioY protein
AXYL_RS07485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXYL_RS07520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXYL_RS07525	COG2878	Part of a membrane complex involved in electron transport
AXYL_RS07540	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AXYL_RS07545	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AXYL_RS07550	COG0251	oxidation-reduction process
AXYL_RS07560	COG3228	Belongs to the MtfA family
AXYL_RS07565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXYL_RS07575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXYL_RS07585	COG0159	tryptophan synthase activity
AXYL_RS07590	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AXYL_RS07595	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXYL_RS07600	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS07605	COG2721	sulfolactate sulfo-lyase activity
AXYL_RS07610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_RS07620	COG1530	ribonuclease E activity
AXYL_RS07635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXYL_RS07640	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AXYL_RS07645	COG3023	N-Acetylmuramoyl-L-alanine amidase
AXYL_RS07655	COG0424	maF-like protein
AXYL_RS07660	COG1399	metal-binding, possibly nucleic acid-binding protein
AXYL_RS07665	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AXYL_RS07670	COG0416	fatty acid biosynthetic process
AXYL_RS07675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXYL_RS07680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXYL_RS07685	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS07690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXYL_RS07695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXYL_RS07720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXYL_RS07730	COG0681	Belongs to the peptidase S26 family
AXYL_RS07735	COG0571	ribonuclease III activity
AXYL_RS07740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AXYL_RS07745	COG1381	Involved in DNA repair and RecF pathway recombination
AXYL_RS07765	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS07775	COG0667	Aldo Keto reductase
AXYL_RS07795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXYL_RS07820	COG0583	DNA-binding transcription factor activity
AXYL_RS07830	COG0791	NLP P60 protein
AXYL_RS07835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXYL_RS07840	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AXYL_RS07850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXYL_RS07855	COG0697	spore germination
AXYL_RS07860	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AXYL_RS07865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXYL_RS07870	COG1802	Transcriptional regulator
AXYL_RS07880	COG0747	negative chemotaxis
AXYL_RS07910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXYL_RS07935	COG2153	protein acetylation
AXYL_RS07945	COG1446	asparaginase
AXYL_RS07950	COG4172	Belongs to the ABC transporter superfamily
AXYL_RS07955	COG0747	negative chemotaxis
AXYL_RS07965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS07990	COG0504	CTP synthase activity
AXYL_RS07995	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AXYL_RS08005	COG0148	phosphopyruvate hydratase activity
AXYL_RS08020	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AXYL_RS08030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXYL_RS08060	COG1981	membrane
AXYL_RS08080	COG0039	L-malate dehydrogenase activity
AXYL_RS08085	COG2188	Transcriptional regulator
AXYL_RS08090	COG2009	succinate dehydrogenase
AXYL_RS08095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AXYL_RS08100	COG1053	succinate dehydrogenase
AXYL_RS08105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXYL_RS08110	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AXYL_RS08115	COG0372	Belongs to the citrate synthase family
AXYL_RS08130	COG0281	malic enzyme
AXYL_RS08130	COG0280	phosphate acetyltransferase
AXYL_RS08140	COG1297	OPT oligopeptide transporter protein
AXYL_RS08145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXYL_RS08160	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AXYL_RS08165	COG1522	sequence-specific DNA binding
AXYL_RS08170	COG0567	Dehydrogenase, E1 component
AXYL_RS08175	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_RS08180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXYL_RS08185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AXYL_RS08190	COG1595	DNA-templated transcription, initiation
AXYL_RS08195	COG3712	iron ion homeostasis
AXYL_RS08200	COG4774	siderophore transport
AXYL_RS08235	COG2183	response to ionizing radiation
AXYL_RS08240	COG1199	ATP-dependent helicase activity
AXYL_RS08260	COG0564	pseudouridine synthase activity
AXYL_RS08265	COG1496	oxidoreductase activity
AXYL_RS08270	COG3243	poly(R)-hydroxyalkanoic acid synthase
AXYL_RS08275	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS08280	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AXYL_RS08300	COG0672	)-iron permease
AXYL_RS08315	COG2823	Periplasmic or secreted lipoprotein
AXYL_RS08325	COG3237	CsbD-like
AXYL_RS08330	COG0189	ligase activity
AXYL_RS08330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXYL_RS08335	COG0189	ligase activity
AXYL_RS08335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXYL_RS08340	COG1132	(ABC) transporter
AXYL_RS08355	COG2833	Protein of unknown function (DUF455)
AXYL_RS08360	COG2951	lytic endotransglycosylase activity
AXYL_RS08385	COG1215	transferase activity, transferring glycosyl groups
AXYL_RS08395	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AXYL_RS08400	COG1024	Enoyl-CoA hydratase
AXYL_RS08405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS08415	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS08420	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_RS08430	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS08440	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS08445	COG2030	dehydratase
AXYL_RS08455	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS08480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXYL_RS08495	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AXYL_RS08500	COG1605	Chorismate mutase
AXYL_RS08500	COG0077	Prephenate dehydratase
AXYL_RS08505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXYL_RS08515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AXYL_RS08520	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AXYL_RS08540	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AXYL_RS08545	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AXYL_RS08550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXYL_RS08580	COG2951	lytic endotransglycosylase activity
AXYL_RS08585	COG0123	including yeast histone deacetylase and acetoin utilization protein
AXYL_RS08610	COG2985	domain, Protein
AXYL_RS08620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS08625	COG1024	Enoyl-CoA hydratase
AXYL_RS08625	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS08635	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS08640	COG0450	alkyl hydroperoxide reductase
AXYL_RS08650	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AXYL_RS08655	COG4208	sulfate ABC transporter
AXYL_RS08660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AXYL_RS08665	COG0175	sulfate reduction
AXYL_RS08695	COG0335	large ribosomal subunit rRNA binding
AXYL_RS08705	COG1162	GTPase activity
AXYL_RS08710	COG0501	Belongs to the peptidase M48B family
AXYL_RS08715	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AXYL_RS08740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AXYL_RS08745	COG3327	negative regulation of DNA-templated transcription, initiation
AXYL_RS08750	COG3396	Phenylacetate-CoA oxygenase
AXYL_RS08755	COG3460	Phenylacetate-CoA oxygenase
AXYL_RS08760	COG3396	Phenylacetate-CoA oxygenase
AXYL_RS08765	COG2151	metal-sulfur cluster biosynthetic enzyme
AXYL_RS08770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_RS08775	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS08780	COG1024	Enoyl-CoA hydratase
AXYL_RS08785	COG2050	protein possibly involved in aromatic compounds catabolism
AXYL_RS08795	COG0534	Mate efflux family protein
AXYL_RS08805	COG0254	rRNA binding
AXYL_RS08810	COG3483	tryptophan 2,3-dioxygenase activity
AXYL_RS08815	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AXYL_RS08820	COG2003	Belongs to the UPF0758 family
AXYL_RS08830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AXYL_RS08835	COG0625	glutathione transferase activity
AXYL_RS08840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXYL_RS08845	COG0642	Histidine kinase
AXYL_RS08865	COG0523	cobalamin synthesis protein
AXYL_RS08870	COG0583	DNA-binding transcription factor activity
AXYL_RS08880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AXYL_RS08885	COG1187	pseudouridine synthase activity
AXYL_RS08890	COG0779	Required for maturation of 30S ribosomal subunits
AXYL_RS08895	COG2251	uridine kinase activity
AXYL_RS08895	COG0195	Participates in both transcription termination and antitermination
AXYL_RS08900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AXYL_RS08905	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AXYL_RS08910	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXYL_RS08915	COG1217	gtp-binding protein TYPA
AXYL_RS08920	COG0583	DNA-binding transcription factor activity
AXYL_RS08935	COG2271	Major facilitator Superfamily
AXYL_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS08955	COG1473	amidohydrolase
AXYL_RS08970	COG0428	transporter
AXYL_RS08975	COG0412	Dienelactone hydrolase
AXYL_RS08980	COG1283	sodium-dependent phosphate transmembrane transporter activity
AXYL_RS08985	COG1760	l-serine dehydratase
AXYL_RS08990	COG2706	6-phosphogluconolactonase activity
AXYL_RS08995	COG0501	Belongs to the peptidase M48B family
AXYL_RS09010	COG0583	DNA-binding transcription factor activity
AXYL_RS09025	COG0583	DNA-binding transcription factor activity
AXYL_RS09030	COG3842	ATPase activity
AXYL_RS09040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXYL_RS09045	COG1840	ABC-type Fe3 transport system, periplasmic component
AXYL_RS09090	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS09100	COG1722	exodeoxyribonuclease VII activity
AXYL_RS09105	COG0142	geranyltranstransferase activity
AXYL_RS09115	COG1469	GTP cyclohydrolase I activity
AXYL_RS09120	COG3739	integral membrane protein
AXYL_RS09125	COG0360	Binds together with S18 to 16S ribosomal RNA
AXYL_RS09130	COG2965	DNA replication, synthesis of RNA primer
AXYL_RS09135	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AXYL_RS09140	COG0359	binds to the 23S rRNA
AXYL_RS09150	COG0305	Participates in initiation and elongation during chromosome replication
AXYL_RS09160	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXYL_RS09195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_RS09245	COG0540	Belongs to the ATCase OTCase family
AXYL_RS09265	COG0477	Major facilitator Superfamily
AXYL_RS09280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AXYL_RS09285	COG2137	regulation of response to DNA damage stimulus
AXYL_RS09300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXYL_RS09320	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_RS09325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AXYL_RS09330	COG0861	Integral membrane protein TerC family
AXYL_RS09335	COG0861	Integral membrane protein TerC family
AXYL_RS09345	COG0181	hydroxymethylbilane synthase activity
AXYL_RS09365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXYL_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS09405	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS09425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AXYL_RS09430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXYL_RS09440	COG0436	Aminotransferase
AXYL_RS09460	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AXYL_RS09465	COG0308	aminopeptidase N
AXYL_RS09480	COG0312	modulator of DNA gyrase
AXYL_RS09485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXYL_RS09490	COG0277	FAD linked oxidase domain protein
AXYL_RS09495	COG0277	FAD linked oxidase domain protein
AXYL_RS09500	COG0277	FAD linked oxidase domain protein
AXYL_RS09505	COG0247	lactate metabolic process
AXYL_RS09535	COG0583	DNA-binding transcription factor activity
AXYL_RS09540	COG0482	sulfurtransferase activity
AXYL_RS09545	COG0730	response to heat
AXYL_RS09550	COG0625	glutathione transferase activity
AXYL_RS09560	COG3909	cytochrome
AXYL_RS09615	COG0697	spore germination
AXYL_RS09640	COG2226	methyltransferase
AXYL_RS09665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_RS09670	COG0069	glutamate synthase activity
AXYL_RS09675	COG2391	methyltransferase activity
AXYL_RS09680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AXYL_RS09715	COG0557	exoribonuclease II activity
AXYL_RS09720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXYL_RS09725	COG0626	cystathionine gamma-synthase activity
AXYL_RS09730	COG3128	pkhd-type hydroxylase
AXYL_RS09735	COG0776	regulation of translation
AXYL_RS09765	COG0642	Histidine kinase
AXYL_RS09770	COG3158	transport of potassium into the cell
AXYL_RS09775	COG0137	argininosuccinate synthase activity
AXYL_RS09780	COG0583	DNA-binding transcription factor activity
AXYL_RS09805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AXYL_RS09810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXYL_RS09835	COG0601	transmembrane transport
AXYL_RS09840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS09855	COG0444	Belongs to the ABC transporter superfamily
AXYL_RS09860	COG4608	Belongs to the ABC transporter superfamily
AXYL_RS09865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS09865	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXYL_RS09875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_RS09880	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AXYL_RS09890	COG3642	lipopolysaccharide core region biosynthetic process
AXYL_RS09900	COG3842	ATPase activity
AXYL_RS09905	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_RS09910	COG1177	transmembrane transport
AXYL_RS09930	COG1322	Protein conserved in bacteria
AXYL_RS09940	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS09950	COG0704	Plays a role in the regulation of phosphate uptake
AXYL_RS09960	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AXYL_RS09965	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AXYL_RS09965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXYL_RS09970	COG1643	Atp-dependent helicase
AXYL_RS09985	COG0438	transferase activity, transferring glycosyl groups
AXYL_RS09990	COG0726	polysaccharide deacetylase
AXYL_RS10005	COG0726	polysaccharide deacetylase
AXYL_RS10025	COG0859	PFAM glycosyl transferase family 9
AXYL_RS10030	COG1132	(ABC) transporter
AXYL_RS10035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXYL_RS10035	COG0475	glutathione-regulated potassium exporter activity
AXYL_RS10045	COG2203	Gaf domain
AXYL_RS10045	COG3706	GGDEF domain
AXYL_RS10045	COG4251	negative regulation of phosphorylation
AXYL_RS10045	COG5001	Diguanylate cyclase
AXYL_RS10065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS10065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXYL_RS10070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_RS10075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXYL_RS10105	COG0419	ATPase involved in DNA repair
AXYL_RS10165	COG1396	sequence-specific DNA binding
AXYL_RS10245	COG5410	chromosome segregation
AXYL_RS10400	COG1530	ribonuclease E activity
AXYL_RS10430	COG2204	response regulator
AXYL_RS10435	COG4191	Histidine kinase
AXYL_RS10440	COG1301	dicarboxylic acid transport
AXYL_RS10450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AXYL_RS10455	COG0799	negative regulation of ribosome biogenesis
AXYL_RS10460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AXYL_RS10470	COG0151	Belongs to the GarS family
AXYL_RS10475	COG0217	transcriptional regulatory protein
AXYL_RS10480	COG0433	COG0433 Predicted ATPase
AXYL_RS10485	COG0473	3-isopropylmalate dehydrogenase activity
AXYL_RS10495	COG2814	Major facilitator Superfamily
AXYL_RS10500	COG1566	PFAM secretion protein HlyD family protein
AXYL_RS10510	COG1846	Transcriptional regulator
AXYL_RS10540	COG3391	amine dehydrogenase activity
AXYL_RS10550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXYL_RS10570	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AXYL_RS10575	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AXYL_RS10585	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AXYL_RS10615	COG2311	Membrane
AXYL_RS10625	COG2358	TRAP transporter, solute receptor (TAXI family
AXYL_RS10630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXYL_RS10655	COG0662	Cupin 2, conserved barrel domain protein
AXYL_RS10660	COG5285	phytanoyl-CoA dioxygenase
AXYL_RS10665	COG0633	Ferredoxin
AXYL_RS10665	COG3217	Mosc domain protein beta barrel domain protein
AXYL_RS10670	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS10675	COG2076	Multidrug Resistance protein
AXYL_RS10680	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AXYL_RS10690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS10740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXYL_RS10745	COG0425	Belongs to the sulfur carrier protein TusA family
AXYL_RS10755	COG0228	four-way junction DNA binding
AXYL_RS10760	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AXYL_RS10765	COG0336	Belongs to the RNA methyltransferase TrmD family
AXYL_RS10770	COG0525	valine-tRNA ligase activity
AXYL_RS10775	COG0105	UTP biosynthetic process
AXYL_RS10780	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXYL_RS10800	COG2976	Protein conserved in bacteria
AXYL_RS10805	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXYL_RS10810	COG1160	GTP binding
AXYL_RS10815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXYL_RS10820	COG1923	regulation of RNA biosynthetic process
AXYL_RS10825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXYL_RS10830	COG0330	HflC and HflK could
AXYL_RS10835	COG0330	HflC and HflK could
AXYL_RS10840	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AXYL_RS10845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AXYL_RS10850	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AXYL_RS10855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXYL_RS10865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXYL_RS10900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_RS10905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXYL_RS10910	COG0439	Biotin carboxylase
AXYL_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS10930	COG2030	dehydratase
AXYL_RS10960	COG4964	Belongs to the GSP D family
AXYL_RS10990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXYL_RS11000	COG1295	ribonuclease BN
AXYL_RS11010	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AXYL_RS11020	COG5002	protein histidine kinase activity
AXYL_RS11035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AXYL_RS11040	COG4783	chaperone-mediated protein folding
AXYL_RS11075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS11090	COG1538	Outer membrane efflux protein
AXYL_RS11110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXYL_RS11120	COG0101	tRNA pseudouridine synthase activity
AXYL_RS11125	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXYL_RS11130	COG0135	phosphoribosylanthranilate isomerase activity
AXYL_RS11140	COG2199	diguanylate cyclase activity
AXYL_RS11140	COG2203	Gaf domain
AXYL_RS11150	COG0840	transmembrane signaling receptor activity
AXYL_RS11160	COG0129	dihydroxy-acid dehydratase activity
AXYL_RS11165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_RS11170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS11175	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXYL_RS11180	COG1609	Transcriptional regulator
AXYL_RS11190	COG4172	Belongs to the ABC transporter superfamily
AXYL_RS11195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS11200	COG0601	transmembrane transport
AXYL_RS11225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXYL_RS11235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AXYL_RS11240	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AXYL_RS11255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXYL_RS11260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXYL_RS11265	COG0004	ammonium transporteR
AXYL_RS11270	COG0347	Belongs to the P(II) protein family
AXYL_RS11280	COG2960	long-chain fatty acid transporting porin activity
AXYL_RS11285	COG0606	chelatase, subunit chli
AXYL_RS11290	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AXYL_RS11295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AXYL_RS11300	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AXYL_RS11305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_RS11305	COG0072	phenylalanine-tRNA ligase activity
AXYL_RS11325	COG0456	acetyltransferase
AXYL_RS11365	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS11370	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS11375	COG0129	dihydroxy-acid dehydratase activity
AXYL_RS11380	COG0583	DNA-binding transcription factor activity
AXYL_RS11385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXYL_RS11395	COG1733	regulation of RNA biosynthetic process
AXYL_RS11410	COG0384	phenazine biosynthesis protein PhzF
AXYL_RS11415	COG0456	acetyltransferase
AXYL_RS11425	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS11450	COG1522	sequence-specific DNA binding
AXYL_RS11490	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS11525	COG0583	DNA-binding transcription factor activity
AXYL_RS11540	COG5265	(ABC) transporter
AXYL_RS11560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXYL_RS11570	COG4977	sequence-specific DNA binding
AXYL_RS11570	COG1917	Cupin 2, conserved barrel domain protein
AXYL_RS11575	COG2223	nitrite transmembrane transporter activity
AXYL_RS11585	COG1215	transferase activity, transferring glycosyl groups
AXYL_RS11590	COG1649	PFAM Uncharacterised BCR, COG1649
AXYL_RS11590	COG0726	polysaccharide deacetylase
AXYL_RS11595	COG0457	Tetratricopeptide repeat
AXYL_RS11640	COG1610	YqeY-like protein
AXYL_RS11650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXYL_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS11665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXYL_RS11715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXYL_RS11720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXYL_RS11750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS11760	COG0506	proline dehydrogenase activity
AXYL_RS11775	COG0583	DNA-binding transcription factor activity
AXYL_RS11790	COG3246	L-lysine catabolic process to acetate
AXYL_RS11795	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS11810	COG0583	DNA-binding transcription factor activity
AXYL_RS11815	COG0625	glutathione transferase activity
AXYL_RS11830	COG2814	Major facilitator Superfamily
AXYL_RS11835	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS11840	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS11870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXYL_RS11880	COG3245	cytochrome
AXYL_RS11885	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AXYL_RS11890	COG1280	lysine exporter protein (LysE YggA)
AXYL_RS11905	COG1280	lysine exporter protein (LysE YggA)
AXYL_RS11925	COG0697	spore germination
AXYL_RS11930	COG0697	spore germination
AXYL_RS11945	COG0477	Major facilitator Superfamily
AXYL_RS11950	COG0583	DNA-binding transcription factor activity
AXYL_RS11955	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXYL_RS11960	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS11970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXYL_RS11975	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AXYL_RS11985	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AXYL_RS11990	COG1129	ABC transporter
AXYL_RS12015	COG0154	amidase activity
AXYL_RS12020	COG2186	Transcriptional regulator
AXYL_RS12030	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS12050	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS12140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_RS12150	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AXYL_RS12170	COG4133	protoheme IX ABC transporter activity
AXYL_RS12175	COG3005	denitrification pathway
AXYL_RS12180	COG3043	anaerobic respiration
AXYL_RS12215	COG3246	L-lysine catabolic process to acetate
AXYL_RS12220	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS12225	COG0583	DNA-binding transcription factor activity
AXYL_RS12250	COG0596	Alpha beta hydrolase
AXYL_RS12255	COG2309	aminopeptidase activity
AXYL_RS12260	COG1335	isochorismatase
AXYL_RS12265	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXYL_RS12285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXYL_RS12310	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXYL_RS12315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS12330	COG2226	methyltransferase
AXYL_RS12335	COG2226	methyltransferase
AXYL_RS12355	COG0129	dihydroxy-acid dehydratase activity
AXYL_RS12360	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS12365	COG5001	Diguanylate cyclase
AXYL_RS12370	COG1024	Enoyl-CoA hydratase
AXYL_RS12375	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS12380	COG0583	DNA-binding transcription factor activity
AXYL_RS12385	COG2610	gluconate transmembrane transporter activity
AXYL_RS12405	COG0583	DNA-binding transcription factor activity
AXYL_RS12410	COG1051	belongs to the nudix hydrolase family
AXYL_RS12420	COG0235	Class ii aldolase
AXYL_RS12425	COG0477	Major facilitator Superfamily
AXYL_RS12445	COG0477	Major facilitator Superfamily
AXYL_RS12450	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS12455	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS12465	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AXYL_RS12480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXYL_RS12495	COG2188	Transcriptional regulator
AXYL_RS12500	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS12520	COG4977	sequence-specific DNA binding
AXYL_RS12535	COG1280	lysine exporter protein (LysE YggA)
AXYL_RS12540	COG5265	(ABC) transporter
AXYL_RS12545	COG1802	Transcriptional regulator
AXYL_RS12580	COG0411	ABC transporter
AXYL_RS12590	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS12610	COG0640	Transcriptional regulator
AXYL_RS12620	COG4774	siderophore transport
AXYL_RS12630	COG1595	DNA-templated transcription, initiation
AXYL_RS12640	COG3712	iron ion homeostasis
AXYL_RS12645	COG1595	DNA-templated transcription, initiation
AXYL_RS12650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_RS12665	COG0583	DNA-binding transcription factor activity
AXYL_RS12670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXYL_RS12695	COG0251	oxidation-reduction process
AXYL_RS12700	COG0583	DNA-binding transcription factor activity
AXYL_RS12710	COG0477	Major facilitator Superfamily
AXYL_RS12735	COG2186	Transcriptional regulator
AXYL_RS12740	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS12745	COG0183	Belongs to the thiolase family
AXYL_RS12760	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS12775	COG0583	DNA-binding transcription factor activity
AXYL_RS12785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS12800	COG0583	DNA-binding transcription factor activity
AXYL_RS12805	COG2814	Major facilitator Superfamily
AXYL_RS12835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXYL_RS12845	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS12860	COG0583	DNA-binding transcription factor activity
AXYL_RS12935	COG4774	siderophore transport
AXYL_RS12940	COG4774	siderophore transport
AXYL_RS12950	COG2366	antibiotic biosynthetic process
AXYL_RS12970	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS12975	COG2186	Transcriptional regulator
AXYL_RS12985	COG0307	riboflavin synthase, alpha
AXYL_RS13000	COG2271	Major facilitator Superfamily
AXYL_RS13010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_RS13020	COG0789	Transcriptional regulator
AXYL_RS13025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS13030	COG2186	Transcriptional regulator
AXYL_RS13035	COG1024	Enoyl-CoA hydratase
AXYL_RS13050	COG2801	Transposase and inactivated derivatives
AXYL_RS13070	COG0022	dehydrogenase e1 component
AXYL_RS13085	COG0583	DNA-binding transcription factor activity
AXYL_RS13090	COG0154	amidase activity
AXYL_RS13140	COG0477	Major facilitator Superfamily
AXYL_RS13170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_RS13180	COG2814	Major facilitator Superfamily
AXYL_RS13185	COG0583	DNA-binding transcription factor activity
AXYL_RS13190	COG0165	Argininosuccinate lyase
AXYL_RS13195	COG0668	transmembrane transport
AXYL_RS13315	COG0747	negative chemotaxis
AXYL_RS13320	COG0601	transmembrane transport
AXYL_RS13325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS13330	COG4172	Belongs to the ABC transporter superfamily
AXYL_RS13335	COG1280	lysine exporter protein (LysE YggA)
AXYL_RS13340	COG4681	YaeQ
AXYL_RS13360	COG2188	Transcriptional regulator
AXYL_RS13390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AXYL_RS13395	COG0066	3-isopropylmalate dehydratase activity
AXYL_RS13425	COG3161	chorismate lyase activity
AXYL_RS13470	COG1187	pseudouridine synthase activity
AXYL_RS13475	COG0583	DNA-binding transcription factor activity
AXYL_RS13500	COG1999	signal sequence binding
AXYL_RS13510	COG0339	signal peptide processing
AXYL_RS13515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AXYL_RS13520	COG4566	intracellular signal transduction
AXYL_RS13535	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_RS13540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXYL_RS13590	COG1360	Flagellar Motor Protein
AXYL_RS13595	COG0745	RESPONSE REGULATOR receiver
AXYL_RS13605	COG0835	chemotaxis
AXYL_RS13610	COG0840	transmembrane signaling receptor activity
AXYL_RS13615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AXYL_RS13620	COG2201	protein-glutamate methylesterase activity
AXYL_RS13625	COG0745	RESPONSE REGULATOR receiver
AXYL_RS13630	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AXYL_RS13635	COG0840	transmembrane signaling receptor activity
AXYL_RS13640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXYL_RS13645	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXYL_RS13660	COG2747	anti-sigma28 factor FlgM
AXYL_RS13670	COG1815	bacterial-type flagellum-dependent cell motility
AXYL_RS13675	COG1558	bacterial-type flagellum-dependent cell motility
AXYL_RS13690	COG4787	bacterial-type flagellum-dependent cell motility
AXYL_RS13710	COG1705	Flagellar rod assembly protein muramidase FlgJ
AXYL_RS13710	COG3951	Flagellar rod assembly protein muramidase FlgJ
AXYL_RS13725	COG0840	transmembrane signaling receptor activity
AXYL_RS13745	COG0840	transmembrane signaling receptor activity
AXYL_RS13755	COG1987	bacterial-type flagellum assembly
AXYL_RS13770	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXYL_RS13780	COG1580	Controls the rotational direction of flagella during chemotaxis
AXYL_RS13795	COG1157	protein secretion by the type III secretion system
AXYL_RS13800	COG1317	bacterial-type flagellum organization
AXYL_RS13805	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXYL_RS13815	COG1677	Flagellar hook-basal body complex protein FliE
AXYL_RS13825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXYL_RS13850	COG1334	flagellar protein FlaG
AXYL_RS13865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS13870	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS13880	COG0285	dihydrofolate synthase activity
AXYL_RS13900	COG1451	nucleotide metabolic process
AXYL_RS13905	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AXYL_RS13915	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AXYL_RS13920	COG0024	Methionine aminopeptidase
AXYL_RS13925	COG0052	Belongs to the universal ribosomal protein uS2 family
AXYL_RS13930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AXYL_RS13935	COG0528	UMP kinase activity
AXYL_RS13940	COG0233	cytoplasmic translational termination
AXYL_RS13945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXYL_RS13950	COG0575	Belongs to the CDS family
AXYL_RS13955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AXYL_RS13960	COG0750	zinc metalloprotease
AXYL_RS13965	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXYL_RS13970	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AXYL_RS13975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXYL_RS13980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXYL_RS13995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AXYL_RS14000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXYL_RS14030	COG2169	Transcriptional regulator
AXYL_RS14030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXYL_RS14035	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_RS14035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXYL_RS14045	COG0330	HflC and HflK could
AXYL_RS14055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AXYL_RS14060	COG2867	negative regulation of translational initiation
AXYL_RS14065	COG2914	Belongs to the UPF0125 (RnfH) family
AXYL_RS14070	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS14075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXYL_RS14095	COG0354	folic acid binding
AXYL_RS14100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AXYL_RS14105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AXYL_RS14110	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXYL_RS14115	COG0084	hydrolase, TatD family'
AXYL_RS14130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXYL_RS14140	COG1024	Enoyl-CoA hydratase
AXYL_RS14145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS14165	COG1137	ATPase activity
AXYL_RS14175	COG0154	amidase activity
AXYL_RS14185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS14190	COG0765	amino acid transport
AXYL_RS14195	COG1126	abc transporter atp-binding protein
AXYL_RS14200	COG0010	Belongs to the arginase family
AXYL_RS14205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXYL_RS14210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_RS14220	COG0095	Lipoate-protein ligase
AXYL_RS14235	COG0625	glutathione transferase activity
AXYL_RS14245	COG1522	sequence-specific DNA binding
AXYL_RS14250	COG0386	Belongs to the glutathione peroxidase family
AXYL_RS14255	COG2814	Major facilitator Superfamily
AXYL_RS14265	COG0840	transmembrane signaling receptor activity
AXYL_RS14280	COG1470	cell adhesion involved in biofilm formation
AXYL_RS14280	COG1388	LysM domain
AXYL_RS14300	COG0513	Belongs to the DEAD box helicase family
AXYL_RS14305	COG1414	Transcriptional regulator
AXYL_RS14325	COG0601	transmembrane transport
AXYL_RS14330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS14345	COG1228	amidohydrolase
AXYL_RS14355	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS14375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS14380	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXYL_RS14385	COG4521	taurine ABC transporter
AXYL_RS14405	COG1966	Carbon starvation protein
AXYL_RS14410	COG2879	small protein
AXYL_RS14420	COG0783	Belongs to the Dps family
AXYL_RS14430	COG1280	lysine exporter protein (LysE YggA)
AXYL_RS14435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXYL_RS14450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXYL_RS14455	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AXYL_RS14460	COG0745	RESPONSE REGULATOR receiver
AXYL_RS14465	COG2205	protein histidine kinase activity
AXYL_RS14480	COG2070	2-Nitropropane dioxygenase
AXYL_RS14535	COG0583	DNA-binding transcription factor activity
AXYL_RS14540	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS14555	COG1021	2,3-dihydroxybenzoate-AMP ligase
AXYL_RS14570	COG1309	transcriptional regulator
AXYL_RS14575	COG1414	Transcriptional regulator
AXYL_RS14580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_RS14650	COG0583	DNA-binding transcription factor activity
AXYL_RS14655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_RS14695	COG2223	nitrite transmembrane transporter activity
AXYL_RS14700	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AXYL_RS14705	COG1140	nitrate reductase beta subunit
AXYL_RS14710	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AXYL_RS14715	COG2181	nitrate reductase activity
AXYL_RS14720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_RS14730	COG0288	reversible hydration of carbon dioxide
AXYL_RS14735	COG1763	Mo-molybdopterin cofactor biosynthetic process
AXYL_RS14740	COG3850	Histidine kinase
AXYL_RS14745	COG2197	response regulator
AXYL_RS14760	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AXYL_RS14760	COG0028	Belongs to the TPP enzyme family
AXYL_RS14775	COG0826	peptidase U32
AXYL_RS14780	COG0826	peptidase U32
AXYL_RS14785	COG3154	lipid carrier protein
AXYL_RS14815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXYL_RS14825	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS14830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_RS14835	COG1802	Transcriptional regulator
AXYL_RS14885	COG0583	DNA-binding transcription factor activity
AXYL_RS14900	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS14905	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS14910	COG2076	Multidrug Resistance protein
AXYL_RS14915	COG1309	transcriptional regulator
AXYL_RS14930	COG0583	DNA-binding transcription factor activity
AXYL_RS14940	COG0346	lactoylglutathione lyase activity
AXYL_RS14950	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AXYL_RS14965	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS14970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS14990	COG3321	synthase
AXYL_RS14990	COG0604	alcohol dehydrogenase
AXYL_RS14990	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS15015	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AXYL_RS15020	COG0765	amino acid transport
AXYL_RS15030	COG1126	abc transporter atp-binding protein
AXYL_RS15045	COG0583	DNA-binding transcription factor activity
AXYL_RS15065	COG4566	intracellular signal transduction
AXYL_RS15095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AXYL_RS15125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_RS15135	COG0028	Belongs to the TPP enzyme family
AXYL_RS15150	COG0346	lactoylglutathione lyase activity
AXYL_RS15160	COG0596	Alpha beta hydrolase
AXYL_RS15165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_RS15180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS15185	COG0765	amino acid transport
AXYL_RS15190	COG1126	abc transporter atp-binding protein
AXYL_RS15200	COG1120	ATPase activity
AXYL_RS15205	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_RS15210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_RS15215	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AXYL_RS15225	COG2814	Major facilitator Superfamily
AXYL_RS15255	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AXYL_RS15270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_RS15275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS15280	COG0577	efflux transmembrane transporter activity
AXYL_RS15280	COG1136	(ABC) transporter
AXYL_RS15285	COG0390	transport system, permease component
AXYL_RS15290	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AXYL_RS15295	COG0586	Pfam SNARE associated Golgi protein
AXYL_RS15305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXYL_RS15320	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS15335	COG0583	DNA-binding transcription factor activity
AXYL_RS15345	COG0235	Class ii aldolase
AXYL_RS15355	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS15365	COG0028	Belongs to the TPP enzyme family
AXYL_RS15375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXYL_RS15375	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS15385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_RS15395	COG4608	Belongs to the ABC transporter superfamily
AXYL_RS15400	COG0444	Belongs to the ABC transporter superfamily
AXYL_RS15405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS15415	COG0747	negative chemotaxis
AXYL_RS15430	COG2202	Pas domain
AXYL_RS15430	COG2200	EAL domain
AXYL_RS15430	COG2199	diguanylate cyclase activity
AXYL_RS15460	COG1063	alcohol dehydrogenase
AXYL_RS15465	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS15495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXYL_RS15505	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_RS15520	COG0583	DNA-binding transcription factor activity
AXYL_RS15525	COG1335	isochorismatase
AXYL_RS15530	COG0583	DNA-binding transcription factor activity
AXYL_RS15540	COG0477	Major facilitator Superfamily
AXYL_RS15545	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS15645	COG0668	transmembrane transport
AXYL_RS15655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_RS15670	COG0642	Histidine kinase
AXYL_RS15680	COG0596	Alpha beta hydrolase
AXYL_RS15690	COG4772	TonB-dependent receptor
AXYL_RS15695	COG3712	iron ion homeostasis
AXYL_RS15700	COG1595	DNA-templated transcription, initiation
AXYL_RS15715	COG2271	Major facilitator Superfamily
AXYL_RS15720	COG2186	Transcriptional regulator
AXYL_RS15725	COG0154	amidase activity
AXYL_RS15730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS15735	COG1024	Enoyl-CoA hydratase
AXYL_RS15770	COG0625	glutathione transferase activity
AXYL_RS15790	COG0531	amino acid
AXYL_RS15800	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS15850	COG0583	DNA-binding transcription factor activity
AXYL_RS15865	COG1619	proteins homologs of microcin C7 resistance protein MccF
AXYL_RS15875	COG0628	permease
AXYL_RS15880	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AXYL_RS15895	COG0583	DNA-binding transcription factor activity
AXYL_RS15905	COG3706	GGDEF domain
AXYL_RS15940	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXYL_RS15950	COG2205	protein histidine kinase activity
AXYL_RS15985	COG3119	arylsulfatase activity
AXYL_RS16020	COG0714	Associated with various cellular activities
AXYL_RS16025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXYL_RS16035	COG1253	flavin adenine dinucleotide binding
AXYL_RS16050	COG4172	Belongs to the ABC transporter superfamily
AXYL_RS16055	COG3568	Endonuclease Exonuclease Phosphatase
AXYL_RS16060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_RS16065	COG0392	lysyltransferase activity
AXYL_RS16085	COG0028	Belongs to the TPP enzyme family
AXYL_RS16090	COG0297	glycogen (starch) synthase activity
AXYL_RS16095	COG0366	Alpha amylase catalytic
AXYL_RS16105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXYL_RS16120	COG1640	4-alpha-glucanotransferase
AXYL_RS16135	COG3300	MHYT domain
AXYL_RS16135	COG5001	Diguanylate cyclase
AXYL_RS16140	COG1289	transmembrane transporter activity
AXYL_RS16150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXYL_RS16175	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS16190	COG2155	Conserved Protein
AXYL_RS16205	COG2204	response regulator
AXYL_RS16210	COG2204	response regulator
AXYL_RS16215	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXYL_RS16230	COG2814	Major facilitator Superfamily
AXYL_RS16245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_RS16250	COG2199	diguanylate cyclase activity
AXYL_RS16250	COG2203	Gaf domain
AXYL_RS16250	COG2200	EAL domain
AXYL_RS16255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXYL_RS16260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS16285	COG1686	Belongs to the peptidase S11 family
AXYL_RS16290	COG0488	(ABC) transporter
AXYL_RS16305	COG0583	DNA-binding transcription factor activity
AXYL_RS16320	COG0688	phosphatidylethanolamine metabolic process
AXYL_RS16335	COG1408	metallophosphoesterase
AXYL_RS16355	COG1464	Belongs to the NlpA lipoprotein family
AXYL_RS16360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXYL_RS16365	COG0010	Belongs to the arginase family
AXYL_RS16390	COG2363	Small membrane protein
AXYL_RS16395	COG0697	spore germination
AXYL_RS16405	COG2133	pyrroloquinoline quinone binding
AXYL_RS16410	COG0625	glutathione transferase activity
AXYL_RS16415	COG0583	DNA-binding transcription factor activity
AXYL_RS16425	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_RS16430	COG1794	racemase activity, acting on amino acids and derivatives
AXYL_RS16450	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS16460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AXYL_RS16470	COG1653	transport
AXYL_RS16475	COG1175	transmembrane transport
AXYL_RS16480	COG0395	ABC-type sugar transport system, permease component
AXYL_RS16485	COG3842	ATPase activity
AXYL_RS16500	COG2205	protein histidine kinase activity
AXYL_RS16505	COG0745	RESPONSE REGULATOR receiver
AXYL_RS16520	COG0783	Belongs to the Dps family
AXYL_RS16525	COG0583	DNA-binding transcription factor activity
AXYL_RS16530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXYL_RS16545	COG0583	DNA-binding transcription factor activity
AXYL_RS16570	COG1840	ABC-type Fe3 transport system, periplasmic component
AXYL_RS16580	COG3842	ATPase activity
AXYL_RS16585	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS16590	COG1741	Belongs to the pirin family
AXYL_RS16595	COG1741	Belongs to the pirin family
AXYL_RS16600	COG0583	DNA-binding transcription factor activity
AXYL_RS16605	COG2204	response regulator
AXYL_RS16615	COG0174	glutamine synthetase
AXYL_RS16620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXYL_RS16625	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AXYL_RS16635	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS16645	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AXYL_RS16650	COG1561	YicC-like family, N-terminal region
AXYL_RS16655	COG3657	addiction module killer protein
AXYL_RS16660	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXYL_RS16665	COG0833	amino acid
AXYL_RS16670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXYL_RS16675	COG0791	NLP P60 protein
AXYL_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS16685	COG2863	cytochrome
AXYL_RS16690	COG3258	Cytochrome c
AXYL_RS16695	COG0194	GDP metabolic process
AXYL_RS16700	COG1758	RNA polymerase activity
AXYL_RS16705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXYL_RS16710	COG1126	abc transporter atp-binding protein
AXYL_RS16715	COG0765	amino acid transport
AXYL_RS16720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS16760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_RS16790	COG4336	lyase activity
AXYL_RS16795	COG0583	DNA-binding transcription factor activity
AXYL_RS16825	COG0583	DNA-binding transcription factor activity
AXYL_RS16835	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXYL_RS16840	COG0560	Phosphoserine phosphatase
AXYL_RS16845	COG0583	DNA-binding transcription factor activity
AXYL_RS16850	COG3842	ATPase activity
AXYL_RS16855	COG4208	sulfate ABC transporter
AXYL_RS16865	COG4181	ATPase activity
AXYL_RS16875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_RS16885	COG0584	glycerophosphoryl diester phosphodiesterase
AXYL_RS16890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AXYL_RS16900	COG0678	peroxiredoxin activity
AXYL_RS16900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXYL_RS16910	COG0789	Transcriptional regulator
AXYL_RS16915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXYL_RS16920	COG2814	Major facilitator Superfamily
AXYL_RS16925	COG0583	DNA-binding transcription factor activity
AXYL_RS16950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXYL_RS16960	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AXYL_RS16965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AXYL_RS16970	COG2252	PERMEase
AXYL_RS16975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXYL_RS16980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_RS17010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS17015	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS17025	COG1024	Enoyl-CoA hydratase
AXYL_RS17035	COG0183	Belongs to the thiolase family
AXYL_RS17040	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS17045	COG0488	(ABC) transporter
AXYL_RS17050	COG0604	alcohol dehydrogenase
AXYL_RS17060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS17070	COG1619	proteins homologs of microcin C7 resistance protein MccF
AXYL_RS17095	COG2212	antiporter activity
AXYL_RS17100	COG1863	multisubunit Na H antiporter MnhE subunit
AXYL_RS17105	COG0651	ATP synthesis coupled electron transport
AXYL_RS17110	COG1006	Multisubunit Na H antiporter MnhC subunit
AXYL_RS17115	COG2111	Na H antiporter
AXYL_RS17115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXYL_RS17135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS17145	COG1309	transcriptional regulator
AXYL_RS17150	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS17165	COG0420	3'-5' exonuclease activity
AXYL_RS17170	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS17175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS17185	COG0583	DNA-binding transcription factor activity
AXYL_RS17190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS17220	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS17225	COG3387	PFAM Glycoside hydrolase 15-related
AXYL_RS17235	COG2199	diguanylate cyclase activity
AXYL_RS17235	COG2203	Gaf domain
AXYL_RS17245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXYL_RS17250	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS17255	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_RS17260	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS17265	COG0583	DNA-binding transcription factor activity
AXYL_RS17285	COG0395	ABC-type sugar transport system, permease component
AXYL_RS17295	COG3842	ATPase activity
AXYL_RS17300	COG3842	ATPase activity
AXYL_RS17325	COG2130	NADP-dependent
AXYL_RS17330	COG1309	transcriptional regulator
AXYL_RS17340	COG1131	(ABC) transporter
AXYL_RS17345	COG0842	Transport permease protein
AXYL_RS17395	COG1902	pentaerythritol trinitrate reductase activity
AXYL_RS17405	COG0154	amidase activity
AXYL_RS17415	COG0583	DNA-binding transcription factor activity
AXYL_RS17430	COG0602	queuosine metabolic process
AXYL_RS17435	COG0720	synthase
AXYL_RS17455	COG1566	PFAM secretion protein HlyD family protein
AXYL_RS17465	COG0400	carboxylic ester hydrolase activity
AXYL_RS17470	COG0833	amino acid
AXYL_RS17485	COG0587	DNA-directed DNA polymerase activity
AXYL_RS17500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXYL_RS17505	COG2271	Major facilitator Superfamily
AXYL_RS17545	COG0765	amino acid transport
AXYL_RS17550	COG0765	amino acid transport
AXYL_RS17555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS17560	COG0436	Aminotransferase
AXYL_RS17565	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXYL_RS17580	COG2124	cytochrome p450
AXYL_RS17595	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_RS17625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXYL_RS17650	COG1073	alpha beta
AXYL_RS17680	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AXYL_RS17690	COG1473	amidohydrolase
AXYL_RS17695	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS17700	COG1802	Transcriptional regulator
AXYL_RS17705	COG1414	Transcriptional regulator
AXYL_RS17715	COG0477	Major facilitator Superfamily
AXYL_RS17720	COG0667	Aldo Keto reductase
AXYL_RS17730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXYL_RS17735	COG1802	Transcriptional regulator
AXYL_RS17745	COG0601	transmembrane transport
AXYL_RS17750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS17755	COG0444	Belongs to the ABC transporter superfamily
AXYL_RS17760	COG4608	Belongs to the ABC transporter superfamily
AXYL_RS17780	COG1309	transcriptional regulator
AXYL_RS17805	COG1683	Conserved Protein
AXYL_RS17815	COG2207	Transcriptional regulator
AXYL_RS17835	COG1360	Flagellar Motor Protein
AXYL_RS17845	COG2885	chlorophyll binding
AXYL_RS17895	COG3795	YCII-related domain
AXYL_RS17900	COG3795	YCII-related domain
AXYL_RS17915	COG4941	Belongs to the sigma-70 factor family
AXYL_RS17925	COG0697	spore germination
AXYL_RS17945	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS17955	COG1846	Transcriptional regulator
AXYL_RS17960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_RS17970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS17980	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXYL_RS18010	COG0642	Histidine kinase
AXYL_RS18040	COG0583	DNA-binding transcription factor activity
AXYL_RS18055	COG2885	chlorophyll binding
AXYL_RS18080	COG0625	glutathione transferase activity
AXYL_RS18090	COG2733	membrane
AXYL_RS18100	COG0583	DNA-binding transcription factor activity
AXYL_RS18105	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS18105	COG1024	Enoyl-CoA hydratase
AXYL_RS18110	COG0183	Belongs to the thiolase family
AXYL_RS18115	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS18120	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS18125	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS18140	COG1129	ABC transporter
AXYL_RS18155	COG0583	DNA-binding transcription factor activity
AXYL_RS18160	COG0583	DNA-binding transcription factor activity
AXYL_RS18180	COG2814	Major facilitator Superfamily
AXYL_RS18210	COG1522	sequence-specific DNA binding
AXYL_RS18215	COG4251	negative regulation of phosphorylation
AXYL_RS18215	COG3706	GGDEF domain
AXYL_RS18215	COG2203	Gaf domain
AXYL_RS18215	COG5001	Diguanylate cyclase
AXYL_RS18220	COG2201	protein-glutamate methylesterase activity
AXYL_RS18250	COG0154	amidase activity
AXYL_RS18335	COG0488	(ABC) transporter
AXYL_RS18365	COG4166	transmembrane transport
AXYL_RS18370	COG2843	Capsule synthesis protein
AXYL_RS18380	COG0583	DNA-binding transcription factor activity
AXYL_RS18385	COG0778	Nitroreductase
AXYL_RS18390	COG0604	alcohol dehydrogenase
AXYL_RS18390	COG3321	synthase
AXYL_RS18410	COG2814	Major facilitator Superfamily
AXYL_RS18415	COG0183	Belongs to the thiolase family
AXYL_RS18420	COG4221	oxidoreductase activity
AXYL_RS18430	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AXYL_RS18435	COG1942	4-Oxalocrotonate Tautomerase
AXYL_RS18465	COG4774	siderophore transport
AXYL_RS18475	COG4774	siderophore transport
AXYL_RS18480	COG3712	iron ion homeostasis
AXYL_RS18490	COG2814	Major facilitator Superfamily
AXYL_RS18510	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS18515	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_RS18515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXYL_RS18535	COG4977	sequence-specific DNA binding
AXYL_RS18535	COG1917	Cupin 2, conserved barrel domain protein
AXYL_RS18575	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS18585	COG0583	DNA-binding transcription factor activity
AXYL_RS18610	COG2072	flavoprotein involved in K transport
AXYL_RS18615	COG0601	transmembrane transport
AXYL_RS18620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS18625	COG0444	Belongs to the ABC transporter superfamily
AXYL_RS18630	COG4608	Belongs to the ABC transporter superfamily
AXYL_RS18635	COG0747	negative chemotaxis
AXYL_RS18640	COG1073	alpha beta
AXYL_RS18700	COG2963	transposase activity
AXYL_RS18705	COG2801	Transposase and inactivated derivatives
AXYL_RS18730	COG4692	amylo-alpha-1,6-glucosidase activity
AXYL_RS18735	COG0583	DNA-binding transcription factor activity
AXYL_RS18740	COG2814	Major facilitator Superfamily
AXYL_RS18745	COG0583	DNA-binding transcription factor activity
AXYL_RS18750	COG2271	Major facilitator Superfamily
AXYL_RS18760	COG0129	dihydroxy-acid dehydratase activity
AXYL_RS18780	COG1335	isochorismatase
AXYL_RS18785	COG4977	sequence-specific DNA binding
AXYL_RS18820	COG1063	alcohol dehydrogenase
AXYL_RS18855	COG0346	lactoylglutathione lyase activity
AXYL_RS18865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_RS18865	COG0543	2 iron, 2 sulfur cluster binding
AXYL_RS18885	COG3706	GGDEF domain
AXYL_RS18910	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AXYL_RS18990	COG1917	Cupin 2, conserved barrel domain protein
AXYL_RS19005	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS19015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXYL_RS19025	COG1595	DNA-templated transcription, initiation
AXYL_RS19030	COG3712	iron ion homeostasis
AXYL_RS19035	COG4774	siderophore transport
AXYL_RS19040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXYL_RS19040	COG0047	phosphoribosylformylglycinamidine synthase activity
AXYL_RS19050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS19050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXYL_RS19055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_RS19065	COG0613	PHP domain protein
AXYL_RS19075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXYL_RS19085	COG0583	DNA-binding transcription factor activity
AXYL_RS19090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXYL_RS19090	COG2146	nitrite reductase [NAD(P)H] activity
AXYL_RS19095	COG2146	nitrite reductase [NAD(P)H] activity
AXYL_RS19095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXYL_RS19110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXYL_RS19115	COG1126	abc transporter atp-binding protein
AXYL_RS19120	COG0765	amino acid transport
AXYL_RS19125	COG0765	amino acid transport
AXYL_RS19145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_RS19150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS19160	COG1850	ribulose-bisphosphate carboxylase activity
AXYL_RS19170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS19185	COG2030	dehydratase
AXYL_RS19210	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS19215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS19220	COG1024	Enoyl-CoA hydratase
AXYL_RS19235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXYL_RS19240	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS19245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_RS19270	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_RS19300	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS19305	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS19365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS19370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS19375	COG1116	anion transmembrane transporter activity
AXYL_RS19420	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_RS19440	COG0737	Belongs to the 5'-nucleotidase family
AXYL_RS19445	COG4604	ABC transporter, ATP-binding protein
AXYL_RS19450	COG4605	iron ion homeostasis
AXYL_RS19455	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_RS19460	COG4607	ABC-type enterochelin transport system periplasmic component
AXYL_RS19465	COG4771	TonB-dependent receptor
AXYL_RS19470	COG0745	RESPONSE REGULATOR receiver
AXYL_RS19485	COG1136	(ABC) transporter
AXYL_RS19500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXYL_RS19505	COG2271	Major facilitator Superfamily
AXYL_RS19510	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AXYL_RS19515	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS19520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AXYL_RS19530	COG1309	transcriptional regulator
AXYL_RS19535	COG0183	Belongs to the thiolase family
AXYL_RS19540	COG1022	Amp-dependent synthetase and ligase
AXYL_RS19570	COG1024	Enoyl-CoA hydratase
AXYL_RS19580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS19590	COG0583	DNA-binding transcription factor activity
AXYL_RS19595	COG1803	Methylglyoxal synthase
AXYL_RS19600	COG2975	iron-sulfur cluster assembly
AXYL_RS19605	COG0633	Ferredoxin
AXYL_RS19610	COG0443	Heat shock 70 kDa protein
AXYL_RS19615	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AXYL_RS19625	COG0822	iron-sulfur transferase activity
AXYL_RS19630	COG1104	cysteine desulfurase activity
AXYL_RS19640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AXYL_RS19645	COG0556	nucleotide-excision repair
AXYL_RS19655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXYL_RS19660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXYL_RS19665	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AXYL_RS19670	COG0740	serine-type endopeptidase activity
AXYL_RS19675	COG0544	peptidyl-prolyl cis-trans isomerase activity
AXYL_RS19680	COG0501	Belongs to the peptidase M48B family
AXYL_RS19690	COG1278	Cold shock
AXYL_RS19700	COG1278	Cold shock
AXYL_RS19725	COG0251	oxidation-reduction process
AXYL_RS19750	COG1309	transcriptional regulator
AXYL_RS19770	COG3008	intermembrane lipid transfer
AXYL_RS19785	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AXYL_RS19790	COG3038	cytochrome b561
AXYL_RS19940	COG0740	serine-type endopeptidase activity
AXYL_RS19965	COG1598	PFAM Uncharacterised protein family UPF0150
AXYL_RS20045	COG1278	Cold shock
AXYL_RS20125	COG2171	N-acyltransferase activity
AXYL_RS20135	COG2890	protein-(glutamine-N5) methyltransferase activity
AXYL_RS20140	COG0488	(ABC) transporter
AXYL_RS20155	COG4771	TonB-dependent receptor
AXYL_RS20160	COG1858	cytochrome C peroxidase
AXYL_RS20170	COG0210	DNA helicase
AXYL_RS20185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXYL_RS20185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXYL_RS20190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXYL_RS20195	COG0196	riboflavin kinase activity
AXYL_RS20200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AXYL_RS20205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AXYL_RS20210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXYL_RS20260	COG0154	amidase activity
AXYL_RS20300	COG0583	DNA-binding transcription factor activity
AXYL_RS20315	COG1902	pentaerythritol trinitrate reductase activity
AXYL_RS20320	COG1126	abc transporter atp-binding protein
AXYL_RS20325	COG0765	amino acid transport
AXYL_RS20330	COG0765	amino acid transport
AXYL_RS20335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS20345	COG1764	response to oxidative stress
AXYL_RS20350	COG1914	H( )-stimulated, divalent metal cation uptake system
AXYL_RS20355	COG0583	DNA-binding transcription factor activity
AXYL_RS20360	COG0583	DNA-binding transcription factor activity
AXYL_RS20375	COG2271	Major facilitator Superfamily
AXYL_RS20380	COG1802	Transcriptional regulator
AXYL_RS20390	COG1024	Enoyl-CoA hydratase
AXYL_RS20395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS20425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXYL_RS20425	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXYL_RS20425	COG0506	proline dehydrogenase activity
AXYL_RS20435	COG3008	intermembrane lipid transfer
AXYL_RS20440	COG2995	paraquat-inducible protein a
AXYL_RS20450	COG4953	penicillin-binding protein 1C
AXYL_RS20455	COG2373	Large extracellular alpha-helical protein
AXYL_RS20460	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXYL_RS20465	COG1278	Cold shock
AXYL_RS20475	COG0183	Belongs to the thiolase family
AXYL_RS20490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXYL_RS20495	COG1570	exodeoxyribonuclease VII activity
AXYL_RS20500	COG0811	peptide transport
AXYL_RS20510	COG1663	tetraacyldisaccharide 4'-kinase activity
AXYL_RS20515	COG2835	tetraacyldisaccharide 4'-kinase activity
AXYL_RS20520	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AXYL_RS20525	COG0563	adenylate kinase activity
AXYL_RS20535	COG0728	peptidoglycan biosynthetic process
AXYL_RS20545	COG0268	Binds directly to 16S ribosomal RNA
AXYL_RS20550	COG0583	DNA-binding transcription factor activity
AXYL_RS20560	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS20565	COG0753	catalase activity
AXYL_RS20570	COG0583	DNA-binding transcription factor activity
AXYL_RS20585	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS20600	COG2186	Transcriptional regulator
AXYL_RS20610	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS20620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXYL_RS20650	COG3384	dioxygenase
AXYL_RS20655	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS20670	COG3971	2-oxopent-4-enoate hydratase activity
AXYL_RS20690	COG1234	tRNA 3'-trailer cleavage
AXYL_RS20700	COG1942	4-Oxalocrotonate Tautomerase
AXYL_RS20710	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS20715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXYL_RS20725	COG1562	ergosterol biosynthetic process
AXYL_RS20735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXYL_RS20760	COG1477	protein flavinylation
AXYL_RS20775	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_RS20790	COG5564	TIM-barrel signal transduction protein
AXYL_RS20795	COG5441	Belongs to the UPF0261 family
AXYL_RS20805	COG1802	Transcriptional regulator
AXYL_RS20810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_RS20815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXYL_RS20835	COG3119	arylsulfatase activity
AXYL_RS20855	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS20860	COG3485	protocatechuate 3,4-dioxygenase
AXYL_RS20870	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXYL_RS20880	COG0542	response to heat
AXYL_RS20890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXYL_RS20900	COG0477	Major facilitator Superfamily
AXYL_RS20930	COG0494	nUDIX hydrolase
AXYL_RS20940	COG0583	DNA-binding transcription factor activity
AXYL_RS20945	COG0443	Heat shock 70 kDa protein
AXYL_RS20975	COG3530	Putative quorum-sensing-regulated virulence factor
AXYL_RS20985	COG1595	DNA-templated transcription, initiation
AXYL_RS20990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXYL_RS20995	COG0625	glutathione transferase activity
AXYL_RS21025	COG0784	Response regulator, receiver
AXYL_RS21025	COG4191	Histidine kinase
AXYL_RS21030	COG2204	response regulator
AXYL_RS21045	COG1522	sequence-specific DNA binding
AXYL_RS21050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_RS21095	COG2801	Transposase and inactivated derivatives
AXYL_RS21100	COG2963	transposase activity
AXYL_RS21140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS21150	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_RS21170	COG2951	lytic endotransglycosylase activity
AXYL_RS21185	COG0583	DNA-binding transcription factor activity
AXYL_RS21200	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS21205	COG1309	transcriptional regulator
AXYL_RS21210	COG0477	Major facilitator Superfamily
AXYL_RS21215	COG1473	amidohydrolase
AXYL_RS21225	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AXYL_RS21240	COG0023	Translation Initiation Factor
AXYL_RS21250	COG2326	polyphosphate kinase activity
AXYL_RS21265	COG2011	ABC-type metal ion transport system permease component
AXYL_RS21270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXYL_RS21290	COG2814	Major facilitator Superfamily
AXYL_RS21305	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS21330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_RS21335	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AXYL_RS21340	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS21340	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXYL_RS21345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS21345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXYL_RS21350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_RS21355	COG0277	FAD linked oxidase domain protein
AXYL_RS21360	COG1414	Transcriptional regulator
AXYL_RS21365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AXYL_RS21390	COG1566	PFAM secretion protein HlyD family protein
AXYL_RS21435	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_RS21465	COG2169	Transcriptional regulator
AXYL_RS21490	COG1272	protein, Hemolysin III
AXYL_RS21540	COG0842	Transport permease protein
AXYL_RS21545	COG1131	(ABC) transporter
AXYL_RS21555	COG4948	Mandelate Racemase Muconate Lactonizing
AXYL_RS21575	COG2824	Alkylphosphonate utilization operon protein PhnA
AXYL_RS21590	COG0348	domain, Protein
AXYL_RS21610	COG3278	Belongs to the heme-copper respiratory oxidase family
AXYL_RS21625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXYL_RS21630	COG0156	8-amino-7-oxononanoate synthase activity
AXYL_RS21640	COG4106	trans-aconitate 2-methyltransferase activity
AXYL_RS21640	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AXYL_RS21655	COG2224	Isocitrate lyase
AXYL_RS21660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AXYL_RS21660	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AXYL_RS21665	COG1858	cytochrome C peroxidase
AXYL_RS21675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXYL_RS21690	COG0736	holo-[acyl-carrier-protein] synthase activity
AXYL_RS21695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AXYL_RS21710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS21735	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AXYL_RS21740	COG4149	molybdate abc transporter
AXYL_RS21745	COG0725	ABC transporter, periplasmic molybdate-binding protein
AXYL_RS21750	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AXYL_RS21770	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AXYL_RS21775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS21780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS21785	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXYL_RS21790	COG4120	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS21800	COG0667	Aldo Keto reductase
AXYL_RS21810	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS21815	COG1024	Enoyl-CoA hydratase
AXYL_RS21825	COG1802	Transcriptional regulator
AXYL_RS21840	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS21855	COG1024	Enoyl-CoA hydratase
AXYL_RS21865	COG0183	Belongs to the thiolase family
AXYL_RS21870	COG0583	DNA-binding transcription factor activity
AXYL_RS21875	COG0516	GMP reductase activity
AXYL_RS21875	COG0517	IMP dehydrogenase activity
AXYL_RS21925	COG4177	L-phenylalanine transmembrane transporter activity
AXYL_RS21940	COG1802	Transcriptional regulator
AXYL_RS21950	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS21955	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS21960	COG0583	DNA-binding transcription factor activity
AXYL_RS21965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXYL_RS21970	COG3384	dioxygenase
AXYL_RS21985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AXYL_RS22040	COG4964	Belongs to the GSP D family
AXYL_RS22085	COG1846	Transcriptional regulator
AXYL_RS22090	COG4172	Belongs to the ABC transporter superfamily
AXYL_RS22095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS22100	COG0601	transmembrane transport
AXYL_RS22115	COG0598	Magnesium transport protein CorA
AXYL_RS22135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXYL_RS22150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXYL_RS22155	COG1045	serine acetyltransferase
AXYL_RS22160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXYL_RS22165	COG0166	Belongs to the GPI family
AXYL_RS22210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXYL_RS22230	COG0438	transferase activity, transferring glycosyl groups
AXYL_RS22240	COG0110	maltose O-acetyltransferase activity
AXYL_RS22245	COG0297	glycogen (starch) synthase activity
AXYL_RS22250	COG2197	response regulator
AXYL_RS22255	COG2197	response regulator
AXYL_RS22265	COG1309	transcriptional regulator
AXYL_RS22270	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS22275	COG0183	Belongs to the thiolase family
AXYL_RS22280	COG1024	Enoyl-CoA hydratase
AXYL_RS22280	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS22290	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS22290	COG1024	Enoyl-CoA hydratase
AXYL_RS22295	COG0183	Belongs to the thiolase family
AXYL_RS22310	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS22320	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS22330	COG4774	siderophore transport
AXYL_RS22340	COG3395	kinase activity
AXYL_RS22345	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXYL_RS22355	COG2186	Transcriptional regulator
AXYL_RS22360	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_RS22370	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS22375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_RS22380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXYL_RS22385	COG1024	Enoyl-CoA hydratase
AXYL_RS22395	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS22400	COG1414	Transcriptional regulator
AXYL_RS22460	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AXYL_RS22470	COG0527	aspartate kinase activity
AXYL_RS22480	COG0825	malonyl-CoA metabolic process
AXYL_RS22490	COG0215	cysteine-tRNA ligase activity
AXYL_RS22505	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXYL_RS22510	COG1968	undecaprenyl-diphosphatase activity
AXYL_RS22515	COG1253	flavin adenine dinucleotide binding
AXYL_RS22530	COG4263	nitrous-oxide reductase activity
AXYL_RS22545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AXYL_RS22565	COG2801	Transposase and inactivated derivatives
AXYL_RS22570	COG0483	inositol monophosphate 1-phosphatase activity
AXYL_RS22590	COG0668	transmembrane transport
AXYL_RS22620	COG0235	Class ii aldolase
AXYL_RS22630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXYL_RS22650	COG1802	Transcriptional regulator
AXYL_RS22665	COG4804	nuclease activity
AXYL_RS22670	COG3360	Dodecin
AXYL_RS22680	COG0583	DNA-binding transcription factor activity
AXYL_RS22685	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS22710	COG0583	DNA-binding transcription factor activity
AXYL_RS22715	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS22745	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AXYL_RS22750	COG2850	peptidyl-arginine hydroxylation
AXYL_RS22760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AXYL_RS22765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_RS22770	COG1994	Peptidase M50
AXYL_RS22775	COG0009	L-threonylcarbamoyladenylate synthase
AXYL_RS22780	COG2321	neutral zinc metallopeptidase
AXYL_RS22800	COG0640	Transcriptional regulator
AXYL_RS22840	COG0583	DNA-binding transcription factor activity
AXYL_RS22855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_RS22865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS22870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS22875	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS23040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_RS23050	COG1024	Enoyl-CoA hydratase
AXYL_RS23080	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS23085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_RS23095	COG0183	Belongs to the thiolase family
AXYL_RS23125	COG1802	Transcriptional regulator
AXYL_RS23140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AXYL_RS23145	COG0463	Glycosyl transferase, family 2
AXYL_RS23190	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS23210	COG0028	Belongs to the TPP enzyme family
AXYL_RS23250	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS23285	COG0297	glycogen (starch) synthase activity
AXYL_RS23300	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS23310	COG0247	lactate metabolic process
AXYL_RS23345	COG0583	DNA-binding transcription factor activity
AXYL_RS23360	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AXYL_RS23360	COG3608	succinylglutamate desuccinylase aspartoacylase
AXYL_RS23380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS23385	COG0765	amino acid transport
AXYL_RS23405	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS23425	COG1396	sequence-specific DNA binding
AXYL_RS23440	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS23450	COG0346	lactoylglutathione lyase activity
AXYL_RS23460	COG0798	PFAM Bile acid sodium symporter
AXYL_RS23475	COG0431	NADPH-dependent FMN reductase
AXYL_RS23480	COG0653	protein targeting
AXYL_RS23490	COG1595	DNA-templated transcription, initiation
AXYL_RS23500	COG4774	siderophore transport
AXYL_RS23505	COG1595	DNA-templated transcription, initiation
AXYL_RS23530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXYL_RS23545	COG0252	asparaginase activity
AXYL_RS23560	COG4774	siderophore transport
AXYL_RS23565	COG3712	iron ion homeostasis
AXYL_RS23570	COG1595	DNA-templated transcription, initiation
AXYL_RS23575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS23580	COG0183	Belongs to the thiolase family
AXYL_RS23590	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS23595	COG0583	DNA-binding transcription factor activity
AXYL_RS23600	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS23605	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS23610	COG1024	Enoyl-CoA hydratase
AXYL_RS23630	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS23635	COG2030	dehydratase
AXYL_RS23655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS23670	COG0330	HflC and HflK could
AXYL_RS23675	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS23680	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS23695	COG2030	dehydratase
AXYL_RS23705	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS23715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS23725	COG0583	DNA-binding transcription factor activity
AXYL_RS23730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS23750	COG3448	diguanylate cyclase activity
AXYL_RS23750	COG4175	Glycine betaine
AXYL_RS23755	COG4176	ABC-type proline glycine betaine transport system permease component
AXYL_RS23765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXYL_RS23770	COG2814	Major facilitator Superfamily
AXYL_RS23775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AXYL_RS23780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXYL_RS23815	COG1686	Belongs to the peptidase S11 family
AXYL_RS23825	COG1846	Transcriptional regulator
AXYL_RS23830	COG2814	Major facilitator Superfamily
AXYL_RS23835	COG0495	leucyl-tRNA aminoacylation
AXYL_RS23850	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AXYL_RS23865	COG0154	amidase activity
AXYL_RS23875	COG0477	Major facilitator Superfamily
AXYL_RS23885	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS23935	COG0583	DNA-binding transcription factor activity
AXYL_RS23940	COG0427	acetyl-CoA hydrolase
AXYL_RS23945	COG0583	DNA-binding transcription factor activity
AXYL_RS23950	COG1511	domain protein
AXYL_RS23950	COG3264	Mechanosensitive ion channel
AXYL_RS24005	COG3842	ATPase activity
AXYL_RS24010	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_RS24015	COG1177	transmembrane transport
AXYL_RS24020	COG3938	Belongs to the proline racemase family
AXYL_RS24030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXYL_RS24035	COG3958	Transketolase
AXYL_RS24040	COG3959	Transketolase, thiamine diphosphate binding domain
AXYL_RS24045	COG1802	Transcriptional regulator
AXYL_RS24050	COG0371	Dehydrogenase
AXYL_RS24055	COG3246	L-lysine catabolic process to acetate
AXYL_RS24060	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS24065	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS24075	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS24090	COG3321	synthase
AXYL_RS24090	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS24090	COG0604	alcohol dehydrogenase
AXYL_RS24095	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS24100	COG0500	methyltransferase
AXYL_RS24105	COG0667	Aldo Keto reductase
AXYL_RS24110	COG2207	Transcriptional regulator
AXYL_RS24120	COG0765	amino acid transport
AXYL_RS24140	COG0251	oxidation-reduction process
AXYL_RS24150	COG1609	Transcriptional regulator
AXYL_RS24160	COG0583	DNA-binding transcription factor activity
AXYL_RS24165	COG1335	isochorismatase
AXYL_RS24170	COG1335	isochorismatase
AXYL_RS24200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXYL_RS24210	COG0411	ABC transporter
AXYL_RS24215	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS24220	COG0683	leucine binding
AXYL_RS24240	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_RS24245	COG1024	Enoyl-CoA hydratase
AXYL_RS24250	COG0022	dehydrogenase e1 component
AXYL_RS24255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXYL_RS24280	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS24285	COG1024	Enoyl-CoA hydratase
AXYL_RS24310	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS24315	COG0583	DNA-binding transcription factor activity
AXYL_RS24320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AXYL_RS24325	COG0511	ligase activity, forming carbon-carbon bonds
AXYL_RS24340	COG1984	allophanate hydrolase subunit 2
AXYL_RS24350	COG1418	mRNA catabolic process
AXYL_RS24355	COG1595	DNA-templated transcription, initiation
AXYL_RS24360	COG3712	iron ion homeostasis
AXYL_RS24365	COG4774	siderophore transport
AXYL_RS24370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS24375	COG0653	protein targeting
AXYL_RS24425	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS24430	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS24450	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_RS24455	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS24455	COG2030	dehydratase
AXYL_RS24460	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS24470	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS24475	COG2030	dehydratase
AXYL_RS24485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS24510	COG1024	Enoyl-CoA hydratase
AXYL_RS24520	COG1024	Enoyl-CoA hydratase
AXYL_RS24540	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS24545	COG2030	dehydratase
AXYL_RS24555	COG2188	Transcriptional regulator
AXYL_RS24565	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS24570	COG4221	oxidoreductase activity
AXYL_RS24600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXYL_RS24635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXYL_RS24645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXYL_RS24650	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AXYL_RS24655	COG1534	Rna-binding protein
AXYL_RS24660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXYL_RS24665	COG0840	transmembrane signaling receptor activity
AXYL_RS24670	COG2233	PERMEase
AXYL_RS24690	COG3842	ATPase activity
AXYL_RS24700	COG0406	alpha-ribazole phosphatase activity
AXYL_RS24705	COG0300	oxidoreductase activity
AXYL_RS24710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AXYL_RS24715	COG0505	Belongs to the CarA family
AXYL_RS24720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXYL_RS24730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS24740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXYL_RS24745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS24760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXYL_RS24770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS24785	COG1177	transmembrane transport
AXYL_RS24800	COG3842	ATPase activity
AXYL_RS24810	COG1074	ATP-dependent DNA helicase activity
AXYL_RS24830	COG1686	Belongs to the peptidase S11 family
AXYL_RS24845	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AXYL_RS24855	COG4974	Belongs to the 'phage' integrase family
AXYL_RS24860	COG0583	DNA-binding transcription factor activity
AXYL_RS24865	COG0028	Belongs to the TPP enzyme family
AXYL_RS24890	COG2030	dehydratase
AXYL_RS24910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXYL_RS24955	COG3842	ATPase activity
AXYL_RS24960	COG1178	ABC-type Fe3 transport system permease component
AXYL_RS24980	COG0583	DNA-binding transcription factor activity
AXYL_RS24985	COG0028	Belongs to the TPP enzyme family
AXYL_RS24990	COG1126	abc transporter atp-binding protein
AXYL_RS24995	COG0765	amino acid transport
AXYL_RS25000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS25005	COG0010	Belongs to the arginase family
AXYL_RS25010	COG1414	Transcriptional regulator
AXYL_RS25015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS25030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_RS25035	COG1414	Transcriptional regulator
AXYL_RS25040	COG0009	L-threonylcarbamoyladenylate synthase
AXYL_RS25045	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXYL_RS25050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AXYL_RS25055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AXYL_RS25065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AXYL_RS25085	COG1301	dicarboxylic acid transport
AXYL_RS25105	COG3454	Phosphonate metabolism
AXYL_RS25110	COG4778	phosphonate C-P lyase system protein PhnL
AXYL_RS25115	COG4107	phosphonate C-P lyase system protein PhnK
AXYL_RS25120	COG3627	carbon phosphorus lyase activity
AXYL_RS25125	COG3626	phosphonate metabolism
AXYL_RS25130	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AXYL_RS25135	COG3624	Phosphonate C-P lyase system protein PhnG
AXYL_RS25140	COG2188	Transcriptional regulator
AXYL_RS25145	COG3454	Phosphonate metabolism
AXYL_RS25150	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AXYL_RS25155	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AXYL_RS25160	COG0583	DNA-binding transcription factor activity
AXYL_RS25165	COG0405	Gamma-glutamyltransferase
AXYL_RS25180	COG3639	organic phosphonate transmembrane transporter activity
AXYL_RS25185	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AXYL_RS25190	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXYL_RS25210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXYL_RS25220	COG0739	heme binding
AXYL_RS25230	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXYL_RS25240	COG0306	phosphate transporter
AXYL_RS25265	COG0789	Transcriptional regulator
AXYL_RS25280	COG0625	glutathione transferase activity
AXYL_RS25300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXYL_RS25305	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXYL_RS25315	COG0126	phosphoglycerate kinase activity
AXYL_RS25320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXYL_RS25325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXYL_RS25330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXYL_RS25335	COG2732	(Barnase) inhibitor
AXYL_RS25345	COG0280	phosphate acetyltransferase
AXYL_RS25345	COG0281	malic enzyme
AXYL_RS25355	COG0436	Aminotransferase
AXYL_RS25360	COG0741	lytic transglycosylase activity
AXYL_RS25365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AXYL_RS25385	COG4575	ribosome binding
AXYL_RS25395	COG0243	molybdopterin cofactor binding
AXYL_RS25400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXYL_RS25405	COG1116	anion transmembrane transporter activity
AXYL_RS25410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS25415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXYL_RS25425	COG1648	precorrin-2 dehydrogenase activity
AXYL_RS25425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXYL_RS25430	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AXYL_RS25435	COG2027	D-alanyl-D-alanine carboxypeptidase
AXYL_RS25450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AXYL_RS25455	COG0343	queuine tRNA-ribosyltransferase activity
AXYL_RS25465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXYL_RS25470	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS25475	COG1024	Enoyl-CoA hydratase
AXYL_RS25495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS25500	COG1862	Preprotein translocase
AXYL_RS25505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXYL_RS25510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXYL_RS25515	COG2801	Transposase and inactivated derivatives
AXYL_RS25535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXYL_RS25545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXYL_RS25550	COG1702	phosphate starvation-inducible protein PhoH
AXYL_RS25555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AXYL_RS25560	COG4535	Mg2 and Co2 transporter CorC
AXYL_RS25565	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AXYL_RS25570	COG0667	Aldo Keto reductase
AXYL_RS25605	COG4191	Histidine kinase
AXYL_RS25610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AXYL_RS25615	COG0697	spore germination
AXYL_RS25625	COG0678	peroxiredoxin activity
AXYL_RS25635	COG0412	Dienelactone hydrolase
AXYL_RS25645	COG0315	cyclic pyranopterin monophosphate synthase activity
AXYL_RS25660	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXYL_RS25665	COG0303	'Molybdopterin
AXYL_RS25670	COG0746	molybdenum cofactor guanylyltransferase activity
AXYL_RS25675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXYL_RS25685	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AXYL_RS25695	COG3383	formate dehydrogenase (NAD+) activity
AXYL_RS25700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXYL_RS25710	COG2223	nitrite transmembrane transporter activity
AXYL_RS25740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AXYL_RS25775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_RS25785	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS25810	COG2188	Transcriptional regulator
AXYL_RS25815	COG0683	leucine binding
AXYL_RS25855	COG0251	oxidation-reduction process
AXYL_RS25860	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS25915	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS25955	COG0671	phosphoesterase, PA-phosphatase related
AXYL_RS25980	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AXYL_RS25985	COG0583	DNA-binding transcription factor activity
AXYL_RS25990	COG1666	GTP binding
AXYL_RS25995	COG1120	ATPase activity
AXYL_RS26000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_RS26005	COG4558	Periplasmic binding protein
AXYL_RS26010	COG3720	iron ion transport
AXYL_RS26025	COG1595	DNA-templated transcription, initiation
AXYL_RS26040	COG2378	regulation of single-species biofilm formation
AXYL_RS26050	COG1113	amino acid transport
AXYL_RS26060	COG1522	sequence-specific DNA binding
AXYL_RS26065	COG1272	protein, Hemolysin III
AXYL_RS26070	COG3191	aminopeptidase activity
AXYL_RS26075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS26080	COG0765	amino acid transport
AXYL_RS26085	COG1126	abc transporter atp-binding protein
AXYL_RS26095	COG4771	TonB-dependent receptor
AXYL_RS26110	COG1120	ATPase activity
AXYL_RS26115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_RS26150	COG1999	signal sequence binding
AXYL_RS26170	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AXYL_RS26180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXYL_RS26185	COG1845	cytochrome c oxidase, subunit III
AXYL_RS26205	COG4772	TonB-dependent receptor
AXYL_RS26210	COG2900	Belongs to the SlyX family
AXYL_RS26225	COG0281	malic enzyme
AXYL_RS26225	COG0280	phosphate acetyltransferase
AXYL_RS26250	COG0697	spore germination
AXYL_RS26290	COG0456	acetyltransferase
AXYL_RS26295	COG1396	sequence-specific DNA binding
AXYL_RS26300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_RS26305	COG3145	DNA-N1-methyladenine dioxygenase activity
AXYL_RS26310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXYL_RS26320	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AXYL_RS26325	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS26330	COG1285	pathogenesis
AXYL_RS26335	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS26340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXYL_RS26355	COG1309	transcriptional regulator
AXYL_RS26375	COG3712	iron ion homeostasis
AXYL_RS26380	COG1595	DNA-templated transcription, initiation
AXYL_RS26390	COG3712	iron ion homeostasis
AXYL_RS26420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXYL_RS26425	COG0330	HflC and HflK could
AXYL_RS26445	COG2807	transmembrane transport
AXYL_RS26450	COG2207	Transcriptional regulator
AXYL_RS26475	COG4106	trans-aconitate 2-methyltransferase activity
AXYL_RS26485	COG0583	DNA-binding transcription factor activity
AXYL_RS26520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXYL_RS26525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS26530	COG0477	Major facilitator Superfamily
AXYL_RS26535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXYL_RS26540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXYL_RS26545	COG1845	cytochrome c oxidase, subunit III
AXYL_RS26550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AXYL_RS26560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_RS26575	COG0625	glutathione transferase activity
AXYL_RS26590	COG2197	response regulator
AXYL_RS26605	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_RS26625	COG3795	YCII-related domain
AXYL_RS26630	COG0667	Aldo Keto reductase
AXYL_RS26645	COG2837	iron assimilation
AXYL_RS26660	COG0730	response to heat
AXYL_RS26665	COG2188	Transcriptional regulator
AXYL_RS26680	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_RS26695	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS26705	COG1024	Enoyl-CoA hydratase
AXYL_RS26705	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS26710	COG0183	Belongs to the thiolase family
AXYL_RS26725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS26730	COG1024	Enoyl-CoA hydratase
AXYL_RS26740	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS26750	COG0183	Belongs to the thiolase family
AXYL_RS26755	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS26760	COG2030	dehydratase
AXYL_RS26770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_RS26775	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS26780	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS26795	COG2084	Dehydrogenase
AXYL_RS26810	COG1280	lysine exporter protein (LysE YggA)
AXYL_RS26845	COG0737	Belongs to the 5'-nucleotidase family
AXYL_RS26855	COG2010	Cytochrome c
AXYL_RS26880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXYL_RS26885	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXYL_RS26925	COG0133	tryptophan synthase activity
AXYL_RS26945	COG1414	Transcriptional regulator
AXYL_RS26950	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_RS26970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXYL_RS26995	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AXYL_RS27000	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AXYL_RS27005	COG4774	siderophore transport
AXYL_RS27010	COG4607	ABC-type enterochelin transport system periplasmic component
AXYL_RS27015	COG4604	ABC transporter, ATP-binding protein
AXYL_RS27020	COG4605	iron ion homeostasis
AXYL_RS27025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_RS27035	COG1132	(ABC) transporter
AXYL_RS27035	COG2375	cellular response to nickel ion
AXYL_RS27045	COG0625	glutathione transferase activity
AXYL_RS27085	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS27085	COG2030	dehydratase
AXYL_RS27090	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS27100	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS27105	COG1454	alcohol dehydrogenase
AXYL_RS27125	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS27135	COG3712	iron ion homeostasis
AXYL_RS27140	COG4774	siderophore transport
AXYL_RS27145	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXYL_RS27170	COG1846	Transcriptional regulator
AXYL_RS27175	COG1764	response to oxidative stress
AXYL_RS27210	COG0668	transmembrane transport
AXYL_RS27220	COG1733	regulation of RNA biosynthetic process
AXYL_RS27245	COG4774	siderophore transport
AXYL_RS27260	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS27265	COG0028	Belongs to the TPP enzyme family
AXYL_RS27270	COG0436	Aminotransferase
AXYL_RS27285	COG1802	Transcriptional regulator
AXYL_RS27305	COG3842	ATPase activity
AXYL_RS27315	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_RS27335	COG2199	diguanylate cyclase activity
AXYL_RS27360	COG0697	spore germination
AXYL_RS27365	COG2267	carboxylic ester hydrolase activity
AXYL_RS27385	COG0583	DNA-binding transcription factor activity
AXYL_RS27390	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXYL_RS27395	COG0459	protein refolding
AXYL_RS27405	COG1846	Transcriptional regulator
AXYL_RS27435	COG1917	Cupin 2, conserved barrel domain protein
AXYL_RS27445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_RS27450	COG0246	Mannitol dehydrogenase
AXYL_RS27455	COG4948	Mandelate Racemase Muconate Lactonizing
AXYL_RS27460	COG2721	sulfolactate sulfo-lyase activity
AXYL_RS27465	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_RS27470	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS27475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_RS27485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_RS27490	COG1063	alcohol dehydrogenase
AXYL_RS27500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AXYL_RS27505	COG1252	NADH dehydrogenase
AXYL_RS27510	COG0284	orotidine-5'-phosphate decarboxylase activity
AXYL_RS27515	COG1546	Belongs to the CinA family
AXYL_RS27520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AXYL_RS27530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXYL_RS27535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AXYL_RS27560	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXYL_RS27565	COG3639	organic phosphonate transmembrane transporter activity
AXYL_RS27570	COG3639	organic phosphonate transmembrane transporter activity
AXYL_RS27590	COG0742	ribosomal rna small subunit methyltransferase
AXYL_RS27595	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AXYL_RS27600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXYL_RS27605	COG3135	benzoate transporter
AXYL_RS27620	COG2814	Major facilitator Superfamily
AXYL_RS27640	COG0012	GTP binding
AXYL_RS27650	COG0193	aminoacyl-tRNA hydrolase activity
AXYL_RS27670	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AXYL_RS27685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AXYL_RS27720	COG0204	Acyl-transferase
AXYL_RS27725	COG1368	sulfuric ester hydrolase activity
AXYL_RS27730	COG2186	Transcriptional regulator
AXYL_RS27740	COG2205	protein histidine kinase activity
AXYL_RS27745	COG0745	RESPONSE REGULATOR receiver
AXYL_RS27750	COG0277	FAD linked oxidase domain protein
AXYL_RS27765	COG0166	Belongs to the GPI family
AXYL_RS27775	COG0438	transferase activity, transferring glycosyl groups
AXYL_RS27780	COG0438	transferase activity, transferring glycosyl groups
AXYL_RS27805	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AXYL_RS27810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXYL_RS27815	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AXYL_RS27840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_RS27845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXYL_RS27865	COG0601	transmembrane transport
AXYL_RS27870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS27875	COG4172	Belongs to the ABC transporter superfamily
AXYL_RS27880	COG0154	amidase activity
AXYL_RS27895	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXYL_RS27895	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXYL_RS27900	COG0509	glycine decarboxylation via glycine cleavage system
AXYL_RS27905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AXYL_RS27920	COG2081	HI0933 family
AXYL_RS27940	COG3706	GGDEF domain
AXYL_RS27950	COG0717	Belongs to the dCTP deaminase family
AXYL_RS27965	COG0489	protein tyrosine kinase activity
AXYL_RS27975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_RS27975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_RS27980	COG1054	Belongs to the UPF0176 family
AXYL_RS27995	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AXYL_RS28005	COG0745	RESPONSE REGULATOR receiver
AXYL_RS28010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXYL_RS28015	COG2200	EAL domain
AXYL_RS28030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS28035	COG1129	ABC transporter
AXYL_RS28035	COG0842	Transport permease protein
AXYL_RS28040	COG0842	Transport permease protein
AXYL_RS28060	COG0778	Nitroreductase
AXYL_RS28065	COG0697	spore germination
AXYL_RS28070	COG1271	oxidase subunit
AXYL_RS28075	COG1294	oxidase, subunit
AXYL_RS28080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_RS28090	COG3712	iron ion homeostasis
AXYL_RS28110	COG1053	succinate dehydrogenase
AXYL_RS28110	COG3976	FMN-binding domain protein
AXYL_RS28115	COG0583	DNA-binding transcription factor activity
AXYL_RS28120	COG3258	Cytochrome c
AXYL_RS28130	COG0625	glutathione transferase activity
AXYL_RS28345	COG0583	DNA-binding transcription factor activity
AXYL_RS28355	COG2267	carboxylic ester hydrolase activity
AXYL_RS28360	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS28365	COG3284	Transcriptional regulator
AXYL_RS28415	COG0438	transferase activity, transferring glycosyl groups
AXYL_RS28450	COG0165	Argininosuccinate lyase
AXYL_RS28455	COG2130	NADP-dependent
AXYL_RS28460	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXYL_RS28470	COG0583	DNA-binding transcription factor activity
AXYL_RS28485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXYL_RS28490	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS28495	COG2072	flavoprotein involved in K transport
AXYL_RS28505	COG3135	benzoate transporter
AXYL_RS28520	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AXYL_RS28525	COG0583	DNA-binding transcription factor activity
AXYL_RS28535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_RS28545	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS28550	COG1802	Transcriptional regulator
AXYL_RS28555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXYL_RS28555	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_RS28585	COG0688	phosphatidylethanolamine metabolic process
AXYL_RS28610	COG0006	proline dipeptidase activity
AXYL_RS28615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_RS28640	COG3275	phosphorelay sensor kinase activity
AXYL_RS28645	COG3279	Response regulator of the LytR AlgR family
AXYL_RS28670	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS28675	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_RS28680	COG1448	Aminotransferase
AXYL_RS28685	COG1473	amidohydrolase
AXYL_RS28695	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS28700	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS28705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS28710	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS28715	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS28720	COG0596	Alpha beta hydrolase
AXYL_RS28740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_RS28755	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS28760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_RS28765	COG0626	cystathionine gamma-synthase activity
AXYL_RS28770	COG0583	DNA-binding transcription factor activity
AXYL_RS28775	COG1522	sequence-specific DNA binding
AXYL_RS28785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AXYL_RS28805	COG1652	LysM domain
AXYL_RS28810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXYL_RS28815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXYL_RS28830	COG0625	glutathione transferase activity
AXYL_RS28835	COG1414	Transcriptional regulator
AXYL_RS28840	COG3734	2-keto-3-deoxy-galactonokinase
AXYL_RS28845	COG0800	Aldolase
AXYL_RS28850	COG4948	Mandelate Racemase Muconate Lactonizing
AXYL_RS28855	COG2271	Major facilitator Superfamily
AXYL_RS28860	COG2814	Major facilitator Superfamily
AXYL_RS28885	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS28895	COG0604	alcohol dehydrogenase
AXYL_RS28910	COG1396	sequence-specific DNA binding
AXYL_RS28915	COG0326	Molecular chaperone. Has ATPase activity
AXYL_RS28925	COG2233	PERMEase
AXYL_RS28950	COG0583	DNA-binding transcription factor activity
AXYL_RS28990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS29010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_RS29020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AXYL_RS29025	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS29030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXYL_RS29035	COG3246	L-lysine catabolic process to acetate
AXYL_RS29045	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS29050	COG0583	DNA-binding transcription factor activity
AXYL_RS29105	COG1695	Transcriptional regulator
AXYL_RS29120	COG0477	Major facilitator Superfamily
AXYL_RS29130	COG0628	permease
AXYL_RS29135	COG0583	DNA-binding transcription factor activity
AXYL_RS29140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_RS29175	COG0625	glutathione transferase activity
AXYL_RS29180	COG1605	Chorismate mutase
AXYL_RS29180	COG0077	Prephenate dehydratase
AXYL_RS29190	COG2081	HI0933 family
AXYL_RS29195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_RS29215	COG1129	ABC transporter
AXYL_RS29235	COG1024	Enoyl-CoA hydratase
AXYL_RS29245	COG0583	DNA-binding transcription factor activity
AXYL_RS29250	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS29265	COG1960	acyl-CoA dehydrogenase activity
AXYL_RS29270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXYL_RS29275	COG1126	abc transporter atp-binding protein
AXYL_RS29280	COG0765	amino acid transport
AXYL_RS29285	COG4597	amino acid ABC transporter
AXYL_RS29290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS29295	COG2884	Cell division ATP-binding protein ftsE
AXYL_RS29300	COG2177	Part of the ABC transporter FtsEX involved in
AXYL_RS29315	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AXYL_RS29325	COG2186	Transcriptional regulator
AXYL_RS29335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXYL_RS29345	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_RS29365	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS29370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXYL_RS29380	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_RS29385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXYL_RS29390	COG0583	DNA-binding transcription factor activity
AXYL_RS29395	COG0129	dihydroxy-acid dehydratase activity
AXYL_RS29405	COG0583	DNA-binding transcription factor activity
AXYL_RS29420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AXYL_RS29425	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AXYL_RS29430	COG1595	DNA-templated transcription, initiation
AXYL_RS29435	COG3712	iron ion homeostasis
AXYL_RS29440	COG4774	siderophore transport
AXYL_RS29445	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_RS29450	COG2031	fatty acid transporter
AXYL_RS29455	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS29460	COG1414	Transcriptional regulator
AXYL_RS29470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_RS29475	COG4829	muconolactone delta-isomerase
AXYL_RS29485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXYL_RS29500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AXYL_RS29505	COG2890	protein-(glutamine-N5) methyltransferase activity
AXYL_RS29510	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AXYL_RS29525	COG1335	isochorismatase
AXYL_RS29535	COG0583	DNA-binding transcription factor activity
AXYL_RS29540	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AXYL_RS29540	COG3264	Mechanosensitive ion channel
AXYL_RS29565	COG2217	Heavy metal translocating P-type atpase
AXYL_RS29575	COG1595	DNA-templated transcription, initiation
AXYL_RS29590	COG1522	sequence-specific DNA binding
AXYL_RS29600	COG5006	permease, DMT superfamily
AXYL_RS29615	COG3622	Belongs to the hyi family
AXYL_RS29620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_RS29625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS29650	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AXYL_RS29655	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS29660	COG0583	DNA-binding transcription factor activity
AXYL_RS29670	COG2186	Transcriptional regulator
AXYL_RS29675	COG3395	kinase activity
AXYL_RS29680	COG2084	Dehydrogenase
AXYL_RS29685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXYL_RS29690	COG3622	Belongs to the hyi family
AXYL_RS29695	COG0235	Class ii aldolase
AXYL_RS29700	COG2084	Dehydrogenase
AXYL_RS29705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXYL_RS29710	COG0683	leucine binding
AXYL_RS29735	COG2188	Transcriptional regulator
AXYL_RS29740	COG1073	alpha beta
AXYL_RS29740	COG2226	methyltransferase
AXYL_RS29750	COG0523	cobalamin synthesis protein
AXYL_RS29755	COG1335	isochorismatase
AXYL_RS29760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXYL_RS29765	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXYL_RS29770	COG1802	Transcriptional regulator
AXYL_RS29775	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AXYL_RS29785	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS29795	COG4774	siderophore transport
AXYL_RS29810	COG4585	Histidine kinase
AXYL_RS29830	COG2197	response regulator
AXYL_RS29835	COG2205	protein histidine kinase activity
AXYL_RS29835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS29840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS29840	COG2198	Histidine kinase
AXYL_RS29840	COG0784	Response regulator, receiver
AXYL_RS29840	COG2205	protein histidine kinase activity
AXYL_RS29845	COG3539	Fimbrial protein
AXYL_RS29875	COG3121	Chaperone
AXYL_RS29880	COG3188	usher protein
AXYL_RS29885	COG3121	Chaperone
AXYL_RS29905	COG2197	response regulator
AXYL_RS29910	COG2205	protein histidine kinase activity
AXYL_RS29910	COG0784	Response regulator, receiver
AXYL_RS29915	COG3119	arylsulfatase activity
AXYL_RS29930	COG1846	Transcriptional regulator
AXYL_RS29945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXYL_RS29955	COG0142	geranyltranstransferase activity
AXYL_RS29965	COG1414	Transcriptional regulator
AXYL_RS29970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AXYL_RS29975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AXYL_RS29980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXYL_RS29985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AXYL_RS30010	COG2801	Transposase and inactivated derivatives
AXYL_RS30020	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXYL_RS30045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXYL_RS30050	COG0793	Belongs to the peptidase S41A family
AXYL_RS30055	COG4942	peptidase
AXYL_RS30060	COG0588	phosphoglycerate mutase activity
AXYL_RS30065	COG1054	Belongs to the UPF0176 family
AXYL_RS30070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXYL_RS30075	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AXYL_RS30080	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AXYL_RS30090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXYL_RS30100	COG2226	methyltransferase
AXYL_RS30105	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AXYL_RS30110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXYL_RS30115	COG0569	domain protein
AXYL_RS30120	COG2204	response regulator
AXYL_RS30125	COG5000	phosphorelay sensor kinase activity
AXYL_RS30135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXYL_RS30140	COG1280	lysine exporter protein (LysE YggA)
AXYL_RS30150	COG1024	Enoyl-CoA hydratase
AXYL_RS30155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AXYL_RS30155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AXYL_RS30160	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AXYL_RS30160	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AXYL_RS30165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS30175	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS30195	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_RS30205	COG2096	Adenosyltransferase
AXYL_RS30230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXYL_RS30240	COG1733	regulation of RNA biosynthetic process
AXYL_RS30260	COG0546	phosphoglycolate phosphatase activity
AXYL_RS30270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AXYL_RS30275	COG0242	peptide deformylase activity
AXYL_RS30280	COG0758	DNA mediated transformation
AXYL_RS30295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_RS30300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_RS30305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AXYL_RS30320	COG1238	metal cluster binding
AXYL_RS30325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXYL_RS30330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_RS30340	COG2801	Transposase and inactivated derivatives
AXYL_RS30355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXYL_RS30360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AXYL_RS30365	COG4988	ABC transporter
AXYL_RS30375	COG1294	oxidase, subunit
AXYL_RS30380	COG1271	oxidase subunit
AXYL_RS30390	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AXYL_RS30400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AXYL_RS30415	COG1137	ATPase activity
AXYL_RS30420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AXYL_RS30430	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AXYL_RS30435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_RS30450	COG1660	Displays ATPase and GTPase activities
AXYL_RS30460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXYL_RS30475	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AXYL_RS30480	COG2823	Periplasmic or secreted lipoprotein
AXYL_RS30485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_RS30495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXYL_RS30505	COG1309	transcriptional regulator
AXYL_RS30510	COG0471	metal ion transport
AXYL_RS30515	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_RS30520	COG0772	Belongs to the SEDS family
AXYL_RS30525	COG0768	penicillin binding
AXYL_RS30535	COG1792	Involved in formation and maintenance of cell shape
AXYL_RS30540	COG1077	Cell shape determining protein MreB Mrl
AXYL_RS30545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXYL_RS30550	COG0154	amidase activity
AXYL_RS30555	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXYL_RS30570	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AXYL_RS30575	COG0708	Exodeoxyribonuclease III
AXYL_RS30585	COG1280	lysine exporter protein (LysE YggA)
AXYL_RS30590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXYL_RS30600	COG0583	DNA-binding transcription factor activity
AXYL_RS30615	COG0583	DNA-binding transcription factor activity
AXYL_RS30640	COG1764	response to oxidative stress
AXYL_RS30645	COG1846	Transcriptional regulator
AXYL_RS30690	COG0730	response to heat
AXYL_RS30710	COG0640	Transcriptional regulator
AXYL_RS30725	COG0456	acetyltransferase
AXYL_RS30750	COG3189	MarR family transcriptional regulator
AXYL_RS30755	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS30760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXYL_RS30780	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AXYL_RS30785	COG0513	Belongs to the DEAD box helicase family
AXYL_RS30795	COG0617	tRNA 3'-terminal CCA addition
AXYL_RS30805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXYL_RS30810	COG2308	Evidence 4 Homologs of previously reported genes of
AXYL_RS30820	COG1305	Transglutaminase-like
AXYL_RS30845	COG2301	Belongs to the HpcH HpaI aldolase family
AXYL_RS30850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_RS30860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AXYL_RS30865	COG1950	PFAM Membrane protein of
AXYL_RS30870	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AXYL_RS30875	COG0438	transferase activity, transferring glycosyl groups
AXYL_RS30885	COG0596	Alpha beta hydrolase
AXYL_RS30890	COG0066	3-isopropylmalate dehydratase activity
AXYL_RS30900	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_RS30905	COG0583	DNA-binding transcription factor activity
AXYL_RS30915	COG0477	Major facilitator Superfamily
AXYL_RS30920	COG0154	amidase activity
AXYL_RS30925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AXYL_RS30935	COG1560	Kdo2-lipid A biosynthetic process
AXYL_RS30940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AXYL_RS30950	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AXYL_RS30955	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AXYL_RS30980	COG0735	belongs to the Fur family
AXYL_RS30985	COG0523	cobalamin synthesis protein
AXYL_RS30995	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AXYL_RS31000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AXYL_RS31010	COG2096	Adenosyltransferase
AXYL_RS31025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXYL_RS31030	COG1609	Transcriptional regulator
AXYL_RS31040	COG0321	lipoyl(octanoyl) transferase activity
AXYL_RS31090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXYL_RS31100	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AXYL_RS31110	COG0859	PFAM glycosyl transferase family 9
AXYL_RS31125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXYL_RS31150	COG0482	sulfurtransferase activity
AXYL_RS31155	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXYL_RS31165	COG1086	Polysaccharide biosynthesis protein
AXYL_RS31190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXYL_RS31215	COG2814	Major facilitator Superfamily
AXYL_RS31225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AXYL_RS31230	COG2076	Multidrug Resistance protein
AXYL_RS31240	COG0500	methyltransferase
AXYL_RS31245	COG0463	Glycosyl transferase, family 2
AXYL_RS31250	COG3958	Transketolase
AXYL_RS31255	COG3959	Transketolase, thiamine diphosphate binding domain
AXYL_RS31270	COG3568	Endonuclease Exonuclease Phosphatase
AXYL_RS31275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AXYL_RS31305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXYL_RS31320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXYL_RS31335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_RS31340	COG1956	GAF domain-containing protein
AXYL_RS31345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_RS31370	COG2186	Transcriptional regulator
AXYL_RS31405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXYL_RS31430	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AXYL_RS31510	COG2814	Major facilitator Superfamily
AXYL_RS31520	COG0625	glutathione transferase activity
AXYL_RS31525	COG0583	DNA-binding transcription factor activity
AXYL_RS31535	COG1473	amidohydrolase
AXYL_RS31540	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AXYL_RS31545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AXYL_RS31550	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXYL_RS31560	COG1965	Belongs to the frataxin family
AXYL_RS31570	COG0019	diaminopimelate decarboxylase activity
AXYL_RS31690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXYL_RS31695	COG1333	cytochrome c biogenesis protein
AXYL_RS31705	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AXYL_RS31740	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS31745	COG1053	succinate dehydrogenase
AXYL_RS31755	COG4232	protein-disulfide reductase activity
AXYL_RS31760	COG1324	tolerance protein
AXYL_RS31765	COG0537	adenosine 5'-monophosphoramidase activity
AXYL_RS31770	COG0203	ribosomal protein L17
AXYL_RS31775	COG0202	RNA polymerase activity
AXYL_RS31780	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AXYL_RS31785	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AXYL_RS31790	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXYL_RS31795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXYL_RS31800	COG0201	protein transport
AXYL_RS31805	COG0200	Binds to the 23S rRNA
AXYL_RS31810	COG1841	ribosomal large subunit assembly
AXYL_RS31815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AXYL_RS31820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AXYL_RS31825	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AXYL_RS31830	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AXYL_RS31835	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AXYL_RS31840	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXYL_RS31845	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AXYL_RS31850	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AXYL_RS31865	COG2207	Transcriptional regulator
AXYL_RS31890	COG4177	L-phenylalanine transmembrane transporter activity
AXYL_RS31905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AXYL_RS31910	COG0255	Belongs to the universal ribosomal protein uL29 family
AXYL_RS31915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AXYL_RS31920	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AXYL_RS31925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AXYL_RS31930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AXYL_RS31935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AXYL_RS31940	COG0089	rRNA binding
AXYL_RS31950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AXYL_RS31955	COG0051	transcription antitermination factor activity, RNA binding
AXYL_RS31960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXYL_RS31965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXYL_RS31970	COG0049	tRNA binding
AXYL_RS31975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AXYL_RS31980	COG0745	RESPONSE REGULATOR receiver
AXYL_RS31995	COG5002	protein histidine kinase activity
AXYL_RS32010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AXYL_RS32015	COG0085	RNA polymerase activity
AXYL_RS32020	COG0222	ribosome binding
AXYL_RS32025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AXYL_RS32030	COG0081	regulation of translation
AXYL_RS32035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AXYL_RS32045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXYL_RS32055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXYL_RS32095	COG1840	ABC-type Fe3 transport system, periplasmic component
AXYL_RS32100	COG3842	ATPase activity
AXYL_RS32110	COG1349	DNA-binding transcription factor activity
AXYL_RS32135	COG0583	DNA-binding transcription factor activity
AXYL_RS32140	COG0252	asparaginase activity
AXYL_RS32145	COG1475	DNA binding
AXYL_RS32155	COG1192	Involved in chromosome partitioning
AXYL_RS32160	COG0357	Ribosomal RNA small subunit methyltransferase G
AXYL_RS32165	COG0445	tRNA wobble uridine modification
AXYL_RS32170	COG1278	Cold shock
AXYL_RS32175	COG3180	Ammonia monooxygenase
AXYL_RS32180	COG0436	Aminotransferase
AXYL_RS32200	COG0642	Histidine kinase
AXYL_RS32210	COG0038	chloride channel
AXYL_RS32235	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AXYL_RS32245	COG0601	transmembrane transport
AXYL_RS32250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_RS32255	COG0444	Belongs to the ABC transporter superfamily
AXYL_RS32260	COG4608	Belongs to the ABC transporter superfamily
AXYL_RS32265	COG1473	amidohydrolase
AXYL_RS32275	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_RS32290	COG2175	clavaminate synthase activity
AXYL_RS32300	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXYL_RS32310	COG0753	catalase activity
AXYL_RS32320	COG0594	ribonuclease P activity
AXYL_RS32325	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AXYL_RS32625	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_RS32845	COG0187	DNA topoisomerase II activity
AXYL_RS33135	COG0551	DNA topoisomerase type I activity
AXYL_RS33135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXYL_RS33530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXYL_RS33540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_RS33595	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXYL_RS33605	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXYL_RS33725	COG0235	Class ii aldolase
AXYL_RS33810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXYL_RS33880	COG0067	glutamate synthase
AXYL_RS33880	COG0069	glutamate synthase activity
AXYL_RS33880	COG0070	glutamate synthase
AXYL_RS33900	COG0067	glutamate synthase
AXYL_RS33900	COG0069	glutamate synthase activity
AXYL_RS33900	COG0070	glutamate synthase
AXYL_RS34005	COG0457	Tetratricopeptide repeat
AXYL_RS34060	COG0726	polysaccharide deacetylase
AXYL_RS34120	COG0583	DNA-binding transcription factor activity
AXYL_RS34125	COG2076	Multidrug Resistance protein