locus-tag	class	description
F0U64_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F0U64_RS00010	COG0592	DNA-directed DNA polymerase activity
F0U64_RS00020	COG2814	Major facilitator Superfamily
F0U64_RS00025	COG0583	DNA-binding transcription factor activity
F0U64_RS00030	COG0583	DNA-binding transcription factor activity
F0U64_RS00055	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F0U64_RS00065	COG0583	DNA-binding transcription factor activity
F0U64_RS00070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS00075	COG0765	amino acid transport
F0U64_RS00080	COG0765	amino acid transport
F0U64_RS00085	COG1126	abc transporter atp-binding protein
F0U64_RS00125	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_RS00130	COG1177	transmembrane transport
F0U64_RS00200	COG1609	Transcriptional regulator
F0U64_RS00210	COG3842	ATPase activity
F0U64_RS00215	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_RS00220	COG1177	transmembrane transport
F0U64_RS00245	COG0251	oxidation-reduction process
F0U64_RS00270	COG0402	S-adenosylhomocysteine deaminase activity
F0U64_RS00280	COG4603	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS00285	COG3845	ABC transporter
F0U64_RS00290	COG1744	ABC transporter substrate-binding protein PnrA-like
F0U64_RS00300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F0U64_RS00315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F0U64_RS00330	COG2814	Major facilitator Superfamily
F0U64_RS00345	COG3781	membrane
F0U64_RS00350	COG1522	sequence-specific DNA binding
F0U64_RS00355	COG0028	Belongs to the TPP enzyme family
F0U64_RS00360	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS00365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS00390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0U64_RS00395	COG2922	Belongs to the Smg family
F0U64_RS00405	COG2358	TRAP transporter, solute receptor (TAXI family
F0U64_RS00425	COG0765	amino acid transport
F0U64_RS00430	COG0765	amino acid transport
F0U64_RS00435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS00440	COG3422	double-strand break repair
F0U64_RS00445	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS00450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0U64_RS00475	COG4977	sequence-specific DNA binding
F0U64_RS00490	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
F0U64_RS00525	COG3339	Conserved Protein
F0U64_RS00555	COG2186	Transcriptional regulator
F0U64_RS00560	COG2814	Major facilitator Superfamily
F0U64_RS00570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F0U64_RS00615	COG1595	DNA-templated transcription, initiation
F0U64_RS00620	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS00635	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS00645	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS00685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F0U64_RS00690	COG0183	Belongs to the thiolase family
F0U64_RS00695	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
F0U64_RS00700	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS00705	COG1473	amidohydrolase
F0U64_RS00715	COG1742	UPF0060 membrane protein
F0U64_RS00730	COG1280	lysine exporter protein (LysE YggA)
F0U64_RS00755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0U64_RS00765	COG0018	arginyl-trna synthetase
F0U64_RS00780	COG0395	ABC-type sugar transport system, permease component
F0U64_RS00785	COG1175	transmembrane transport
F0U64_RS00790	COG1653	transport
F0U64_RS00795	COG3842	ATPase activity
F0U64_RS00800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0U64_RS00805	COG1609	Transcriptional regulator
F0U64_RS00815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0U64_RS00830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F0U64_RS00850	COG0583	DNA-binding transcription factor activity
F0U64_RS00870	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F0U64_RS00875	COG1280	lysine exporter protein (LysE YggA)
F0U64_RS00880	COG0513	Belongs to the DEAD box helicase family
F0U64_RS00885	COG5339	Protein conserved in bacteria
F0U64_RS00890	COG5339	Protein conserved in bacteria
F0U64_RS00895	COG1228	amidohydrolase
F0U64_RS00905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS00910	COG0601	transmembrane transport
F0U64_RS00915	COG0747	negative chemotaxis
F0U64_RS00920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F0U64_RS00930	COG2207	Transcriptional regulator
F0U64_RS00930	COG3708	Transcriptional regulator
F0U64_RS00940	COG1104	cysteine desulfurase activity
F0U64_RS00950	COG0583	DNA-binding transcription factor activity
F0U64_RS00980	COG2969	positive regulation of protein catabolic process
F0U64_RS00985	COG0625	glutathione transferase activity
F0U64_RS00990	COG2857	Cytochrome c1
F0U64_RS00995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F0U64_RS01000	COG0723	plastoquinol--plastocyanin reductase activity
F0U64_RS01005	COG1970	mechanosensitive ion channel activity
F0U64_RS01010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F0U64_RS01015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_RS01030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0U64_RS01035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0U64_RS01040	COG0537	adenosine 5'-monophosphoramidase activity
F0U64_RS01045	COG0140	phosphoribosyl-ATP diphosphatase activity
F0U64_RS01055	COG0107	imidazoleglycerol-phosphate synthase activity
F0U64_RS01060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F0U64_RS01065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F0U64_RS01070	COG0131	Imidazoleglycerol-phosphate dehydratase
F0U64_RS01075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0U64_RS01080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F0U64_RS01085	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F0U64_RS01090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F0U64_RS01100	COG0842	Transport permease protein
F0U64_RS01105	COG1131	(ABC) transporter
F0U64_RS01115	COG2853	Lipoprotein
F0U64_RS01120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F0U64_RS01125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0U64_RS01130	COG1127	ABC transporter
F0U64_RS01135	COG2070	2-Nitropropane dioxygenase
F0U64_RS01145	COG0477	Major facilitator Superfamily
F0U64_RS01160	COG0583	DNA-binding transcription factor activity
F0U64_RS01165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F0U64_RS01170	COG0511	ligase activity, forming carbon-carbon bonds
F0U64_RS01185	COG1984	allophanate hydrolase subunit 2
F0U64_RS01200	COG0067	glutamate synthase
F0U64_RS01200	COG0069	glutamate synthase activity
F0U64_RS01200	COG0070	glutamate synthase
F0U64_RS01225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0U64_RS01245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0U64_RS01275	COG1612	heme a metabolic process
F0U64_RS01285	COG1999	signal sequence binding
F0U64_RS01305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F0U64_RS01310	COG2814	Major facilitator Superfamily
F0U64_RS01320	COG0438	transferase activity, transferring glycosyl groups
F0U64_RS01360	COG1074	ATP-dependent DNA helicase activity
F0U64_RS01385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F0U64_RS01395	COG4774	siderophore transport
F0U64_RS01400	COG4592	Periplasmic binding protein
F0U64_RS01405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS01410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS01415	COG1120	ATPase activity
F0U64_RS01420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_RS01435	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
F0U64_RS01460	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F0U64_RS01465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F0U64_RS01470	COG2814	Major facilitator Superfamily
F0U64_RS01475	COG0583	DNA-binding transcription factor activity
F0U64_RS01485	COG2423	ornithine cyclodeaminase activity
F0U64_RS01490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F0U64_RS01495	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F0U64_RS01505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0U64_RS01515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F0U64_RS01520	COG0463	Glycosyl transferase, family 2
F0U64_RS01570	COG0737	Belongs to the 5'-nucleotidase family
F0U64_RS01585	COG2188	Transcriptional regulator
F0U64_RS01595	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F0U64_RS01600	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F0U64_RS01615	COG0840	transmembrane signaling receptor activity
F0U64_RS01620	COG2814	Major facilitator Superfamily
F0U64_RS01635	COG3188	usher protein
F0U64_RS01695	COG1802	Transcriptional regulator
F0U64_RS01705	COG3069	C4-dicarboxylate transmembrane transporter activity
F0U64_RS01710	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_RS01735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS01745	COG0747	negative chemotaxis
F0U64_RS01770	COG1464	Belongs to the NlpA lipoprotein family
F0U64_RS01775	COG0431	NADPH-dependent FMN reductase
F0U64_RS01780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_RS01785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_RS01790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS01805	COG2011	ABC-type metal ion transport system permease component
F0U64_RS01810	COG1464	Belongs to the NlpA lipoprotein family
F0U64_RS01815	COG1116	anion transmembrane transporter activity
F0U64_RS01820	COG3585	molybdate ion transport
F0U64_RS01825	COG3064	Membrane
F0U64_RS01850	COG1607	acyl-coa hydrolase
F0U64_RS01865	COG0437	4 iron, 4 sulfur cluster binding
F0U64_RS01870	COG2864	formate dehydrogenase
F0U64_RS01885	COG3276	selenocysteine insertion sequence binding
F0U64_RS01895	COG1215	transferase activity, transferring glycosyl groups
F0U64_RS01900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_RS01905	COG1305	Transglutaminase-like
F0U64_RS01910	COG0709	Synthesizes selenophosphate from selenide and ATP
F0U64_RS01940	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_RS01945	COG3284	Transcriptional regulator
F0U64_RS01950	COG0134	indole-3-glycerol-phosphate synthase activity
F0U64_RS01955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F0U64_RS01960	COG0512	Glutamine amidotransferase of anthranilate synthase
F0U64_RS01970	COG0546	phosphoglycolate phosphatase activity
F0U64_RS01975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F0U64_RS01980	COG2967	ApaG domain
F0U64_RS01990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_RS01995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0U64_RS02005	COG0037	tRNA processing
F0U64_RS02020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_RS02035	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS02040	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS02055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0U64_RS02080	COG3473	Maleate cis-trans isomerase
F0U64_RS02085	COG0583	DNA-binding transcription factor activity
F0U64_RS02100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0U64_RS02110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_RS02115	COG1024	Enoyl-CoA hydratase
F0U64_RS02130	COG0356	it plays a direct role in the translocation of protons across the membrane
F0U64_RS02145	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F0U64_RS02150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F0U64_RS02155	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F0U64_RS02165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F0U64_RS02175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F0U64_RS02180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F0U64_RS02185	COG0210	DNA helicase
F0U64_RS02200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F0U64_RS02205	COG4221	oxidoreductase activity
F0U64_RS02215	COG2171	N-acyltransferase activity
F0U64_RS02225	COG2195	Cleaves the N-terminal amino acid of tripeptides
F0U64_RS02235	COG4608	Belongs to the ABC transporter superfamily
F0U64_RS02240	COG0444	Belongs to the ABC transporter superfamily
F0U64_RS02250	COG0601	transmembrane transport
F0U64_RS02255	COG0747	negative chemotaxis
F0U64_RS02260	COG2988	succinylglutamate desuccinylase activity
F0U64_RS02270	COG0583	DNA-binding transcription factor activity
F0U64_RS02275	COG0747	negative chemotaxis
F0U64_RS02285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F0U64_RS02290	COG1024	Enoyl-CoA hydratase
F0U64_RS02295	COG1024	Enoyl-CoA hydratase
F0U64_RS02305	COG1309	transcriptional regulator
F0U64_RS02320	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_RS02335	COG2814	Major facilitator Superfamily
F0U64_RS02350	COG1764	response to oxidative stress
F0U64_RS02355	COG0583	DNA-binding transcription factor activity
F0U64_RS02365	COG1595	DNA-templated transcription, initiation
F0U64_RS02370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0U64_RS02375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS02390	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0U64_RS02410	COG1129	ABC transporter
F0U64_RS02425	COG1802	Transcriptional regulator
F0U64_RS02435	COG0583	DNA-binding transcription factor activity
F0U64_RS02445	COG2988	succinylglutamate desuccinylase activity
F0U64_RS02455	COG2918	glutathione biosynthetic process
F0U64_RS02485	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F0U64_RS02490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_RS02500	COG2721	sulfolactate sulfo-lyase activity
F0U64_RS02505	COG2721	sulfolactate sulfo-lyase activity
F0U64_RS02510	COG2188	Transcriptional regulator
F0U64_RS02515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_RS02520	COG2813	Specifically methylates the guanine in position
F0U64_RS02520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_RS02525	COG2223	nitrite transmembrane transporter activity
F0U64_RS02535	COG2860	membrane
F0U64_RS02540	COG1802	Transcriptional regulator
F0U64_RS02550	COG1984	allophanate hydrolase subunit 2
F0U64_RS02555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F0U64_RS02565	COG0583	DNA-binding transcription factor activity
F0U64_RS02575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_RS02590	COG2132	Multicopper oxidase
F0U64_RS02615	COG0745	RESPONSE REGULATOR receiver
F0U64_RS02620	COG2226	methyltransferase
F0U64_RS02635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F0U64_RS02645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F0U64_RS02655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F0U64_RS02660	COG0351	phosphomethylpyrimidine kinase
F0U64_RS02665	COG2022	thiamine diphosphate biosynthetic process
F0U64_RS02670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0U64_RS02675	COG4771	TonB-dependent receptor
F0U64_RS02685	COG2186	Transcriptional regulator
F0U64_RS02700	COG1063	alcohol dehydrogenase
F0U64_RS02710	COG0765	amino acid transport
F0U64_RS02715	COG1126	abc transporter atp-binding protein
F0U64_RS02720	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_RS02725	COG0246	Mannitol dehydrogenase
F0U64_RS02740	COG1194	a g-specific adenine glycosylase
F0U64_RS02765	COG2177	Part of the ABC transporter FtsEX involved in
F0U64_RS02770	COG2884	Cell division ATP-binding protein ftsE
F0U64_RS02775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS02780	COG4597	amino acid ABC transporter
F0U64_RS02785	COG0765	amino acid transport
F0U64_RS02790	COG1126	abc transporter atp-binding protein
F0U64_RS02815	COG1129	ABC transporter
F0U64_RS02820	COG4177	L-phenylalanine transmembrane transporter activity
F0U64_RS02835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_RS02840	COG2081	HI0933 family
F0U64_RS02850	COG1605	Chorismate mutase
F0U64_RS02850	COG0077	Prephenate dehydratase
F0U64_RS02885	COG0477	Major facilitator Superfamily
F0U64_RS02895	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F0U64_RS02900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F0U64_RS02920	COG0237	dephospho-CoA kinase activity
F0U64_RS02925	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
F0U64_RS02955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS02960	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_RS02975	COG3833	ABC-type maltose transport systems, permease component
F0U64_RS02980	COG1175	transmembrane transport
F0U64_RS02985	COG3842	ATPase activity
F0U64_RS03005	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F0U64_RS03040	COG0410	ABC transporter
F0U64_RS03075	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS03080	COG1024	Enoyl-CoA hydratase
F0U64_RS03120	COG4638	Rieske (2fe-2S)
F0U64_RS03125	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F0U64_RS03130	COG1335	isochorismatase
F0U64_RS03135	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS03145	COG0741	lytic transglycosylase activity
F0U64_RS03150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F0U64_RS03155	COG0352	thiamine-phosphate diphosphorylase activity
F0U64_RS03170	COG1678	Uncharacterized ACR, COG1678
F0U64_RS03175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F0U64_RS03200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_RS03205	COG0436	Aminotransferase
F0U64_RS03210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS03220	COG0765	amino acid transport
F0U64_RS03225	COG1126	abc transporter atp-binding protein
F0U64_RS03230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0U64_RS03240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0U64_RS03245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0U64_RS03255	COG3842	ATPase activity
F0U64_RS03260	COG1175	transmembrane transport
F0U64_RS03280	COG0557	exoribonuclease II activity
F0U64_RS03285	COG3150	esterase
F0U64_RS03290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0U64_RS03295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_RS03300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F0U64_RS03305	COG0511	ligase activity, forming carbon-carbon bonds
F0U64_RS03310	COG0439	Biotin carboxylase
F0U64_RS03315	COG2264	protein methyltransferase activity
F0U64_RS03325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F0U64_RS03325	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
F0U64_RS03350	COG1696	Membrane protein involved in D-alanine export
F0U64_RS03400	COG0583	DNA-binding transcription factor activity
F0U64_RS03415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0U64_RS03420	COG1042	CoA-binding domain protein
F0U64_RS03420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0U64_RS03420	COG0045	succinate-CoA ligase (ADP-forming) activity
F0U64_RS03425	COG1335	isochorismatase
F0U64_RS03430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS03435	COG1116	anion transmembrane transporter activity
F0U64_RS03450	COG3028	Belongs to the UPF0307 family
F0U64_RS03455	COG0312	modulator of DNA gyrase
F0U64_RS03460	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F0U64_RS03470	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS03475	COG4177	L-phenylalanine transmembrane transporter activity
F0U64_RS03490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F0U64_RS03495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F0U64_RS03500	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F0U64_RS03510	COG0316	Belongs to the HesB IscA family
F0U64_RS03525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F0U64_RS03540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F0U64_RS03545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F0U64_RS03560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0U64_RS03560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0U64_RS03575	COG2766	serine protein kinase
F0U64_RS03580	COG2718	Belongs to the UPF0229 family
F0U64_RS03585	COG2719	SpoVR family
F0U64_RS03595	COG0583	DNA-binding transcription factor activity
F0U64_RS03600	COG1942	4-Oxalocrotonate Tautomerase
F0U64_RS03610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0U64_RS03620	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS03640	COG2770	Histidine kinase
F0U64_RS03640	COG2208	phosphoserine phosphatase activity
F0U64_RS03650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0U64_RS03655	COG2172	sigma factor antagonist activity
F0U64_RS03660	COG1366	Belongs to the anti-sigma-factor antagonist family
F0U64_RS03700	COG1388	LysM domain
F0U64_RS03700	COG0741	lytic transglycosylase activity
F0U64_RS03705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0U64_RS03710	COG2226	methyltransferase
F0U64_RS03715	COG0328	RNA-DNA hybrid ribonuclease activity
F0U64_RS03725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_RS03730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F0U64_RS03745	COG1671	Belongs to the UPF0178 family
F0U64_RS03760	COG0786	glutamate:sodium symporter activity
F0U64_RS03770	COG0463	Glycosyl transferase, family 2
F0U64_RS03775	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F0U64_RS03790	COG0583	DNA-binding transcription factor activity
F0U64_RS03810	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS03830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_RS03840	COG0583	DNA-binding transcription factor activity
F0U64_RS03850	COG1346	cytolysis
F0U64_RS03860	COG0697	spore germination
F0U64_RS03865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS03880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F0U64_RS03890	COG1522	sequence-specific DNA binding
F0U64_RS03905	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F0U64_RS03910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS03925	COG0823	Involved in the tonB-independent uptake of proteins
F0U64_RS03935	COG0848	biopolymer transport protein
F0U64_RS03940	COG0811	peptide transport
F0U64_RS03945	COG0824	Thioesterase
F0U64_RS03950	COG0442	prolyl-tRNA aminoacylation
F0U64_RS03980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_RS03995	COG2084	Dehydrogenase
F0U64_RS04000	COG0405	Gamma-glutamyltransferase
F0U64_RS04040	COG0129	dihydroxy-acid dehydratase activity
F0U64_RS04045	COG4654	Cytochrome c, class I
F0U64_RS04050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0U64_RS04060	COG1522	sequence-specific DNA binding
F0U64_RS04100	COG0583	DNA-binding transcription factor activity
F0U64_RS04110	COG1473	amidohydrolase
F0U64_RS04115	COG0418	dihydroorotase activity
F0U64_RS04120	COG0488	(ABC) transporter
F0U64_RS04130	COG2001	Belongs to the MraZ family
F0U64_RS04135	COG0275	rRNA processing
F0U64_RS04140	COG3116	cell division
F0U64_RS04150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F0U64_RS04155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0U64_RS04160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F0U64_RS04170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F0U64_RS04175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0U64_RS04180	COG1181	Belongs to the D-alanine--D-alanine ligase family
F0U64_RS04185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F0U64_RS04195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F0U64_RS04200	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
F0U64_RS04210	COG0739	heme binding
F0U64_RS04215	COG0653	protein targeting
F0U64_RS04230	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS04235	COG0028	Belongs to the TPP enzyme family
F0U64_RS04245	COG0300	oxidoreductase activity
F0U64_RS04250	COG1522	sequence-specific DNA binding
F0U64_RS04265	COG2239	Acts as a magnesium transporter
F0U64_RS04275	COG2855	membrane
F0U64_RS04280	COG0583	DNA-binding transcription factor activity
F0U64_RS04285	COG1473	amidohydrolase
F0U64_RS04290	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS04295	COG0483	inositol monophosphate 1-phosphatase activity
F0U64_RS04300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS04300	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F0U64_RS04305	COG1501	Belongs to the glycosyl hydrolase 31 family
F0U64_RS04310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F0U64_RS04315	COG2011	ABC-type metal ion transport system permease component
F0U64_RS04330	COG1595	DNA-templated transcription, initiation
F0U64_RS04335	COG3712	iron ion homeostasis
F0U64_RS04355	COG0840	transmembrane signaling receptor activity
F0U64_RS04360	COG0583	DNA-binding transcription factor activity
F0U64_RS04370	COG0735	belongs to the Fur family
F0U64_RS04390	COG2818	Glycosylase
F0U64_RS04395	COG1368	sulfuric ester hydrolase activity
F0U64_RS04400	COG2982	Protein involved in outer membrane biogenesis
F0U64_RS04415	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS04445	COG2154	pterin-4-alpha-carbinolamine dehydratase
F0U64_RS04460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_RS04470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F0U64_RS04475	COG3178	'Phosphotransferase
F0U64_RS04485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_RS04490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F0U64_RS04495	COG1929	Belongs to the glycerate kinase type-1 family
F0U64_RS04500	COG0469	pyruvate kinase activity
F0U64_RS04505	COG0700	Nucleoside recognition
F0U64_RS04510	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS04515	COG0242	peptide deformylase activity
F0U64_RS04535	COG0204	Acyl-transferase
F0U64_RS04540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F0U64_RS04545	COG0751	glycine-tRNA ligase activity
F0U64_RS04550	COG0752	glycyl-tRNA synthetase alpha subunit
F0U64_RS04555	COG1024	Enoyl-CoA hydratase
F0U64_RS04575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS04580	COG2030	dehydratase
F0U64_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS04600	COG2070	2-Nitropropane dioxygenase
F0U64_RS04610	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS04615	COG0183	Belongs to the thiolase family
F0U64_RS04625	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS04635	COG1024	Enoyl-CoA hydratase
F0U64_RS04645	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
F0U64_RS04655	COG2301	Belongs to the HpcH HpaI aldolase family
F0U64_RS04660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0U64_RS04670	COG0617	tRNA 3'-terminal CCA addition
F0U64_RS04685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F0U64_RS04695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F0U64_RS04700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F0U64_RS04705	COG0586	Pfam SNARE associated Golgi protein
F0U64_RS04715	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0U64_RS04720	COG0802	atpase or kinase
F0U64_RS04725	COG0114	fumarate hydratase activity
F0U64_RS04735	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS04750	COG0531	amino acid
F0U64_RS04755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS04765	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS04770	COG0583	DNA-binding transcription factor activity
F0U64_RS04775	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0U64_RS04785	COG1304	FMN binding
F0U64_RS04795	COG2175	clavaminate synthase activity
F0U64_RS04805	COG0583	DNA-binding transcription factor activity
F0U64_RS04815	COG0579	oxidoreductase
F0U64_RS04825	COG0259	pyridoxamine-phosphate oxidase activity
F0U64_RS04840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_RS04845	COG0577	efflux transmembrane transporter activity
F0U64_RS04845	COG1136	(ABC) transporter
F0U64_RS04850	COG1538	Outer membrane efflux protein
F0U64_RS04855	COG0583	DNA-binding transcription factor activity
F0U64_RS04875	COG1136	(ABC) transporter
F0U64_RS04875	COG0577	efflux transmembrane transporter activity
F0U64_RS04905	COG1136	(ABC) transporter
F0U64_RS04910	COG0577	efflux transmembrane transporter activity
F0U64_RS04910	COG1136	(ABC) transporter
F0U64_RS04920	COG1566	PFAM secretion protein HlyD family protein
F0U64_RS04925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F0U64_RS04960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F0U64_RS04970	COG0800	Aldolase
F0U64_RS04985	COG0463	Glycosyl transferase, family 2
F0U64_RS04985	COG1216	Glycosyl transferase, family 2
F0U64_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS05015	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
F0U64_RS05035	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F0U64_RS05040	COG4638	Rieske (2fe-2S)
F0U64_RS05065	COG0747	negative chemotaxis
F0U64_RS05070	COG0601	transmembrane transport
F0U64_RS05075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS05080	COG0444	Belongs to the ABC transporter superfamily
F0U64_RS05085	COG4608	Belongs to the ABC transporter superfamily
F0U64_RS05105	COG2746	aminoglycoside 3-N-acetyltransferase activity
F0U64_RS05110	COG0488	(ABC) transporter
F0U64_RS05135	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F0U64_RS05140	COG2894	cell division
F0U64_RS05145	COG0850	regulation of cytokinetic process
F0U64_RS05150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0U64_RS05160	COG1294	oxidase, subunit
F0U64_RS05165	COG0514	ATP-dependent DNA helicase (RecQ)
F0U64_RS05180	COG4191	Histidine kinase
F0U64_RS05185	COG2255	four-way junction helicase activity
F0U64_RS05195	COG1090	epimerase
F0U64_RS05200	COG0632	four-way junction helicase activity
F0U64_RS05225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_RS05235	COG0006	proline dipeptidase activity
F0U64_RS05250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F0U64_RS05255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS05270	COG4783	chaperone-mediated protein folding
F0U64_RS05310	COG2814	Major facilitator Superfamily
F0U64_RS05315	COG4771	TonB-dependent receptor
F0U64_RS05325	COG0513	Belongs to the DEAD box helicase family
F0U64_RS05340	COG1058	Belongs to the CinA family
F0U64_RS05340	COG1546	Belongs to the CinA family
F0U64_RS05345	COG1414	Transcriptional regulator
F0U64_RS05360	COG0167	dihydroorotate dehydrogenase activity
F0U64_RS05365	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
F0U64_RS05370	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F0U64_RS05460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0U64_RS05465	COG0735	belongs to the Fur family
F0U64_RS05470	COG0497	DNA recombination
F0U64_RS05480	COG1420	regulation of RNA biosynthetic process
F0U64_RS05485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F0U64_RS05495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F0U64_RS05505	COG0443	Heat shock 70 kDa protein
F0U64_RS05510	COG0484	heat shock protein binding
F0U64_RS05520	COG0612	Peptidase, M16
F0U64_RS05545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0U64_RS05580	COG0840	transmembrane signaling receptor activity
F0U64_RS05585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_RS05600	COG0745	RESPONSE REGULATOR receiver
F0U64_RS05605	COG2205	protein histidine kinase activity
F0U64_RS05610	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F0U64_RS05615	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F0U64_RS05620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F0U64_RS05635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0U64_RS05645	COG1193	negative regulation of DNA recombination
F0U64_RS05650	COG0492	ferredoxin-NADP+ reductase activity
F0U64_RS05655	COG1674	ftsk spoiiie
F0U64_RS05660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F0U64_RS05665	COG0251	oxidation-reduction process
F0U64_RS05670	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_RS05675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F0U64_RS05675	COG0517	IMP dehydrogenase activity
F0U64_RS05695	COG0601	transmembrane transport
F0U64_RS05710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0U64_RS05715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F0U64_RS05720	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F0U64_RS05760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_RS05770	COG4774	siderophore transport
F0U64_RS05775	COG4607	ABC-type enterochelin transport system periplasmic component
F0U64_RS05780	COG4604	ABC transporter, ATP-binding protein
F0U64_RS05785	COG4605	iron ion homeostasis
F0U64_RS05790	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS05795	COG1132	(ABC) transporter
F0U64_RS05800	COG1132	(ABC) transporter
F0U64_RS05800	COG2375	cellular response to nickel ion
F0U64_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS05825	COG3022	response to hydroperoxide
F0U64_RS05830	COG1289	transmembrane transporter activity
F0U64_RS05835	COG0028	Belongs to the TPP enzyme family
F0U64_RS05840	COG0440	acetolactate synthase activity
F0U64_RS05845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F0U64_RS05850	COG1183	phosphatidylcholine synthase activity
F0U64_RS05860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F0U64_RS05865	COG1185	polyribonucleotide nucleotidyltransferase activity
F0U64_RS05875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0U64_RS05895	COG2207	Transcriptional regulator
F0U64_RS05920	COG0149	triose-phosphate isomerase activity
F0U64_RS05925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F0U64_RS05940	COG2885	chlorophyll binding
F0U64_RS05940	COG3047	cAMP biosynthetic process
F0U64_RS05965	COG0840	transmembrane signaling receptor activity
F0U64_RS05985	COG1910	domain protein
F0U64_RS06020	COG1116	anion transmembrane transporter activity
F0U64_RS06035	COG1595	DNA-templated transcription, initiation
F0U64_RS06040	COG3712	iron ion homeostasis
F0U64_RS06060	COG0642	Histidine kinase
F0U64_RS06070	COG2851	Citrate transporter
F0U64_RS06075	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS06095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F0U64_RS06115	COG3604	Transcriptional regulator
F0U64_RS06120	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
F0U64_RS06125	COG3813	Protein conserved in bacteria
F0U64_RS06130	COG2354	Protein conserved in bacteria
F0U64_RS06135	COG4772	TonB-dependent receptor
F0U64_RS06140	COG1522	sequence-specific DNA binding
F0U64_RS06170	COG0747	negative chemotaxis
F0U64_RS06190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_RS06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_RS06205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0U64_RS06210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_RS06215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_RS06235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_RS06245	COG1309	transcriptional regulator
F0U64_RS06250	COG0583	DNA-binding transcription factor activity
F0U64_RS06270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0U64_RS06295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS06300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0U64_RS06305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0U64_RS06310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0U64_RS06315	COG0649	NAD binding
F0U64_RS06320	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F0U64_RS06330	COG1034	ATP synthesis coupled electron transport
F0U64_RS06335	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
F0U64_RS06340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0U64_RS06350	COG0713	ATP synthesis coupled electron transport
F0U64_RS06365	COG1007	ATP synthesis coupled electron transport
F0U64_RS06375	COG4774	siderophore transport
F0U64_RS06380	COG0560	Phosphoserine phosphatase
F0U64_RS06385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F0U64_RS06390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F0U64_RS06395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F0U64_RS06405	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0U64_RS06410	COG0450	alkyl hydroperoxide reductase
F0U64_RS06425	COG1214	PFAM Peptidase M22, glycoprotease
F0U64_RS06430	COG1573	uracil-dna glycosylase
F0U64_RS06435	COG0477	Major facilitator Superfamily
F0U64_RS06440	COG1196	nuclear chromosome segregation
F0U64_RS06450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F0U64_RS06455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_RS06465	COG2917	probably involved in intracellular septation
F0U64_RS06470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0U64_RS06475	COG1122	ATPase activity
F0U64_RS06480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F0U64_RS06485	COG1268	BioY protein
F0U64_RS06520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0U64_RS06555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F0U64_RS06560	COG2878	Part of a membrane complex involved in electron transport
F0U64_RS06575	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F0U64_RS06580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F0U64_RS06585	COG0251	oxidation-reduction process
F0U64_RS06595	COG3228	Belongs to the MtfA family
F0U64_RS06600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0U64_RS06610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0U64_RS06620	COG0159	tryptophan synthase activity
F0U64_RS06625	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F0U64_RS06630	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F0U64_RS06635	COG1530	ribonuclease E activity
F0U64_RS06640	COG0564	pseudouridine synthase activity
F0U64_RS06645	COG0546	phosphoglycolate phosphatase activity
F0U64_RS06650	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F0U64_RS06655	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
F0U64_RS06670	COG0424	maF-like protein
F0U64_RS06675	COG1399	metal-binding, possibly nucleic acid-binding protein
F0U64_RS06680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F0U64_RS06690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0U64_RS06695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F0U64_RS06705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0U64_RS06710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0U64_RS06735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_RS06740	COG0481	GTPase activity
F0U64_RS06745	COG0681	Belongs to the peptidase S26 family
F0U64_RS06750	COG0571	ribonuclease III activity
F0U64_RS06755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F0U64_RS06760	COG1381	Involved in DNA repair and RecF pathway recombination
F0U64_RS06810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F0U64_RS06835	COG0583	DNA-binding transcription factor activity
F0U64_RS06845	COG0791	NLP P60 protein
F0U64_RS06855	COG3193	protein, possibly involved in utilization of glycolate and propanediol
F0U64_RS06865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0U64_RS06870	COG0697	spore germination
F0U64_RS06875	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F0U64_RS06880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0U64_RS06900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_RS06925	COG2153	protein acetylation
F0U64_RS06935	COG1446	asparaginase
F0U64_RS06940	COG4172	Belongs to the ABC transporter superfamily
F0U64_RS06945	COG0747	negative chemotaxis
F0U64_RS06980	COG0504	CTP synthase activity
F0U64_RS06990	COG0148	phosphopyruvate hydratase activity
F0U64_RS07005	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F0U64_RS07015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0U64_RS07055	COG1981	membrane
F0U64_RS07075	COG0039	L-malate dehydrogenase activity
F0U64_RS07080	COG2188	Transcriptional regulator
F0U64_RS07085	COG2009	succinate dehydrogenase
F0U64_RS07090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F0U64_RS07095	COG1053	succinate dehydrogenase
F0U64_RS07100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F0U64_RS07105	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F0U64_RS07110	COG0372	Belongs to the citrate synthase family
F0U64_RS07125	COG0280	phosphate acetyltransferase
F0U64_RS07125	COG0281	malic enzyme
F0U64_RS07135	COG1297	OPT oligopeptide transporter protein
F0U64_RS07140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0U64_RS07155	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F0U64_RS07160	COG1522	sequence-specific DNA binding
F0U64_RS07165	COG0567	Dehydrogenase, E1 component
F0U64_RS07170	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0U64_RS07175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0U64_RS07180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F0U64_RS07185	COG1595	DNA-templated transcription, initiation
F0U64_RS07190	COG3712	iron ion homeostasis
F0U64_RS07195	COG4774	siderophore transport
F0U64_RS07230	COG2183	response to ionizing radiation
F0U64_RS07235	COG1199	ATP-dependent helicase activity
F0U64_RS07245	COG0564	pseudouridine synthase activity
F0U64_RS07250	COG1496	oxidoreductase activity
F0U64_RS07255	COG3243	poly(R)-hydroxyalkanoic acid synthase
F0U64_RS07260	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS07265	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
F0U64_RS07290	COG2831	hemolysin activation secretion protein
F0U64_RS07295	COG3210	domain, Protein
F0U64_RS07305	COG3210	domain, Protein
F0U64_RS07320	COG2823	Periplasmic or secreted lipoprotein
F0U64_RS07330	COG3237	CsbD-like
F0U64_RS07335	COG0189	ligase activity
F0U64_RS07335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F0U64_RS07340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F0U64_RS07340	COG0189	ligase activity
F0U64_RS07345	COG1132	(ABC) transporter
F0U64_RS07360	COG2833	Protein of unknown function (DUF455)
F0U64_RS07365	COG2258	MOSC domain
F0U64_RS07370	COG2951	lytic endotransglycosylase activity
F0U64_RS07385	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS07395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0U64_RS07405	COG1696	Membrane protein involved in D-alanine export
F0U64_RS07425	COG1215	transferase activity, transferring glycosyl groups
F0U64_RS07435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F0U64_RS07460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F0U64_RS07475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F0U64_RS07485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0U64_RS07495	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F0U64_RS07500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F0U64_RS07520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F0U64_RS07525	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
F0U64_RS07530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_RS07560	COG2951	lytic endotransglycosylase activity
F0U64_RS07565	COG0123	including yeast histone deacetylase and acetoin utilization protein
F0U64_RS07590	COG2985	domain, Protein
F0U64_RS07595	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS07600	COG0450	alkyl hydroperoxide reductase
F0U64_RS07610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F0U64_RS07615	COG4208	sulfate ABC transporter
F0U64_RS07625	COG0175	sulfate reduction
F0U64_RS07635	COG2895	sulfate adenylyltransferase (ATP) activity
F0U64_RS07655	COG0335	large ribosomal subunit rRNA binding
F0U64_RS07660	COG0494	nUDIX hydrolase
F0U64_RS07665	COG1162	GTPase activity
F0U64_RS07670	COG0501	Belongs to the peptidase M48B family
F0U64_RS07675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F0U64_RS07680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F0U64_RS07685	COG3327	negative regulation of DNA-templated transcription, initiation
F0U64_RS07690	COG3396	Phenylacetate-CoA oxygenase
F0U64_RS07695	COG3460	Phenylacetate-CoA oxygenase
F0U64_RS07700	COG3396	Phenylacetate-CoA oxygenase
F0U64_RS07705	COG2151	metal-sulfur cluster biosynthetic enzyme
F0U64_RS07710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0U64_RS07715	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_RS07720	COG1024	Enoyl-CoA hydratase
F0U64_RS07725	COG2050	protein possibly involved in aromatic compounds catabolism
F0U64_RS07735	COG0534	Mate efflux family protein
F0U64_RS07750	COG3483	tryptophan 2,3-dioxygenase activity
F0U64_RS07755	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
F0U64_RS07760	COG2003	Belongs to the UPF0758 family
F0U64_RS07770	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F0U64_RS07775	COG0625	glutathione transferase activity
F0U64_RS07780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_RS07805	COG0523	cobalamin synthesis protein
F0U64_RS07810	COG0523	cobalamin synthesis protein
F0U64_RS07815	COG0583	DNA-binding transcription factor activity
F0U64_RS07830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F0U64_RS07835	COG1187	pseudouridine synthase activity
F0U64_RS07840	COG0779	Required for maturation of 30S ribosomal subunits
F0U64_RS07845	COG2251	uridine kinase activity
F0U64_RS07845	COG0195	Participates in both transcription termination and antitermination
F0U64_RS07850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F0U64_RS07855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F0U64_RS07860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F0U64_RS07865	COG1217	gtp-binding protein TYPA
F0U64_RS07885	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS07890	COG1473	amidohydrolase
F0U64_RS07895	COG1611	Belongs to the LOG family
F0U64_RS07910	COG0412	Dienelactone hydrolase
F0U64_RS07920	COG1760	l-serine dehydratase
F0U64_RS07925	COG0501	Belongs to the peptidase M48B family
F0U64_RS07945	COG0583	DNA-binding transcription factor activity
F0U64_RS07950	COG3842	ATPase activity
F0U64_RS07960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0U64_RS07965	COG1840	ABC-type Fe3 transport system, periplasmic component
F0U64_RS07985	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS07995	COG1722	exodeoxyribonuclease VII activity
F0U64_RS08000	COG0142	geranyltranstransferase activity
F0U64_RS08010	COG1469	GTP cyclohydrolase I activity
F0U64_RS08015	COG3739	integral membrane protein
F0U64_RS08020	COG0360	Binds together with S18 to 16S ribosomal RNA
F0U64_RS08025	COG2965	DNA replication, synthesis of RNA primer
F0U64_RS08030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F0U64_RS08035	COG0359	binds to the 23S rRNA
F0U64_RS08045	COG0305	Participates in initiation and elongation during chromosome replication
F0U64_RS08055	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F0U64_RS08090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS08140	COG0540	Belongs to the ATCase OTCase family
F0U64_RS08175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F0U64_RS08180	COG2137	regulation of response to DNA damage stimulus
F0U64_RS08205	COG0045	succinate-CoA ligase (ADP-forming) activity
F0U64_RS08210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F0U64_RS08215	COG0861	Integral membrane protein TerC family
F0U64_RS08220	COG0861	Integral membrane protein TerC family
F0U64_RS08225	COG0181	hydroxymethylbilane synthase activity
F0U64_RS08245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F0U64_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS08285	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS08305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
F0U64_RS08310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0U64_RS08320	COG0436	Aminotransferase
F0U64_RS08340	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F0U64_RS08345	COG0308	aminopeptidase N
F0U64_RS08360	COG0312	modulator of DNA gyrase
F0U64_RS08365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F0U64_RS08370	COG0277	FAD linked oxidase domain protein
F0U64_RS08375	COG0277	FAD linked oxidase domain protein
F0U64_RS08380	COG0277	FAD linked oxidase domain protein
F0U64_RS08385	COG0247	lactate metabolic process
F0U64_RS08415	COG0583	DNA-binding transcription factor activity
F0U64_RS08420	COG0482	sulfurtransferase activity
F0U64_RS08425	COG0730	response to heat
F0U64_RS08430	COG0625	glutathione transferase activity
F0U64_RS08440	COG3909	cytochrome
F0U64_RS08470	COG0628	permease
F0U64_RS08480	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F0U64_RS08600	COG0697	spore germination
F0U64_RS08655	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
F0U64_RS08665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0U64_RS08670	COG0069	glutamate synthase activity
F0U64_RS08675	COG2391	methyltransferase activity
F0U64_RS08680	COG0679	Auxin Efflux Carrier
F0U64_RS08710	COG0557	exoribonuclease II activity
F0U64_RS08715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0U64_RS08725	COG3128	pkhd-type hydroxylase
F0U64_RS08730	COG0776	regulation of translation
F0U64_RS08760	COG0642	Histidine kinase
F0U64_RS08765	COG3158	transport of potassium into the cell
F0U64_RS08770	COG0137	argininosuccinate synthase activity
F0U64_RS08775	COG0583	DNA-binding transcription factor activity
F0U64_RS08780	COG3618	amidohydrolase
F0U64_RS08800	COG2945	thiolester hydrolase activity
F0U64_RS08800	COG0596	Alpha beta hydrolase
F0U64_RS08805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F0U64_RS08810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0U64_RS08820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F0U64_RS08820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_RS08830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_RS08835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F0U64_RS08845	COG3642	lipopolysaccharide core region biosynthetic process
F0U64_RS08855	COG3842	ATPase activity
F0U64_RS08860	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_RS08865	COG1177	transmembrane transport
F0U64_RS08885	COG1322	Protein conserved in bacteria
F0U64_RS08895	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS08905	COG0704	Plays a role in the regulation of phosphate uptake
F0U64_RS08915	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
F0U64_RS08920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F0U64_RS08920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F0U64_RS08925	COG1643	Atp-dependent helicase
F0U64_RS08930	COG0395	ABC-type sugar transport system, permease component
F0U64_RS08935	COG1116	anion transmembrane transporter activity
F0U64_RS08950	COG0438	transferase activity, transferring glycosyl groups
F0U64_RS08955	COG0726	polysaccharide deacetylase
F0U64_RS08970	COG0726	polysaccharide deacetylase
F0U64_RS08995	COG1132	(ABC) transporter
F0U64_RS09000	COG0475	glutathione-regulated potassium exporter activity
F0U64_RS09000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0U64_RS09010	COG5001	Diguanylate cyclase
F0U64_RS09010	COG2203	Gaf domain
F0U64_RS09010	COG3706	GGDEF domain
F0U64_RS09010	COG4251	negative regulation of phosphorylation
F0U64_RS09020	COG1530	ribonuclease E activity
F0U64_RS09050	COG2204	response regulator
F0U64_RS09055	COG4191	Histidine kinase
F0U64_RS09060	COG1301	dicarboxylic acid transport
F0U64_RS09070	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F0U64_RS09075	COG0799	negative regulation of ribosome biogenesis
F0U64_RS09080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F0U64_RS09090	COG0151	Belongs to the GarS family
F0U64_RS09095	COG0217	transcriptional regulatory protein
F0U64_RS09100	COG0433	COG0433 Predicted ATPase
F0U64_RS09105	COG0473	3-isopropylmalate dehydrogenase activity
F0U64_RS09115	COG2814	Major facilitator Superfamily
F0U64_RS09120	COG1566	PFAM secretion protein HlyD family protein
F0U64_RS09130	COG1846	Transcriptional regulator
F0U64_RS09160	COG3391	amine dehydrogenase activity
F0U64_RS09170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0U64_RS09190	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F0U64_RS09195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F0U64_RS09205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F0U64_RS09230	COG1309	transcriptional regulator
F0U64_RS09235	COG2311	Membrane
F0U64_RS09240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0U64_RS09265	COG0662	Cupin 2, conserved barrel domain protein
F0U64_RS09270	COG5285	phytanoyl-CoA dioxygenase
F0U64_RS09275	COG0633	Ferredoxin
F0U64_RS09275	COG3217	Mosc domain protein beta barrel domain protein
F0U64_RS09280	COG2076	Multidrug Resistance protein
F0U64_RS09295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS09310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0U64_RS09315	COG0425	Belongs to the sulfur carrier protein TusA family
F0U64_RS09325	COG0228	four-way junction DNA binding
F0U64_RS09335	COG0336	Belongs to the RNA methyltransferase TrmD family
F0U64_RS09340	COG1396	sequence-specific DNA binding
F0U64_RS09345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS09350	COG0765	amino acid transport
F0U64_RS09355	COG1126	abc transporter atp-binding protein
F0U64_RS09360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS09365	COG0525	valine-tRNA ligase activity
F0U64_RS09370	COG0105	UTP biosynthetic process
F0U64_RS09375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F0U64_RS09395	COG2976	Protein conserved in bacteria
F0U64_RS09400	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0U64_RS09405	COG1160	GTP binding
F0U64_RS09410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0U64_RS09415	COG1923	regulation of RNA biosynthetic process
F0U64_RS09420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F0U64_RS09425	COG0330	HflC and HflK could
F0U64_RS09430	COG0330	HflC and HflK could
F0U64_RS09435	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
F0U64_RS09445	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F0U64_RS09450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F0U64_RS09470	COG0438	transferase activity, transferring glycosyl groups
F0U64_RS09480	COG2755	lipolytic protein G-D-S-L family
F0U64_RS09480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F0U64_RS09510	COG4964	Belongs to the GSP D family
F0U64_RS09540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F0U64_RS09550	COG1295	ribonuclease BN
F0U64_RS09560	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F0U64_RS09585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F0U64_RS09615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_RS09620	COG2274	protein secretion by the type I secretion system
F0U64_RS09630	COG1538	Outer membrane efflux protein
F0U64_RS09650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F0U64_RS09660	COG0101	tRNA pseudouridine synthase activity
F0U64_RS09665	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F0U64_RS09685	COG0596	Alpha beta hydrolase
F0U64_RS09720	COG0129	dihydroxy-acid dehydratase activity
F0U64_RS09725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_RS09730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_RS09735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F0U64_RS09740	COG1609	Transcriptional regulator
F0U64_RS09760	COG4172	Belongs to the ABC transporter superfamily
F0U64_RS09765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS09770	COG0601	transmembrane transport
F0U64_RS09780	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_RS09810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0U64_RS09815	COG2197	response regulator
F0U64_RS09825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F0U64_RS09830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F0U64_RS09845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0U64_RS09850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F0U64_RS09855	COG0004	ammonium transporteR
F0U64_RS09860	COG0347	Belongs to the P(II) protein family
F0U64_RS09875	COG2960	long-chain fatty acid transporting porin activity
F0U64_RS09885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F0U64_RS09890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F0U64_RS09895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F0U64_RS09900	COG0072	phenylalanine-tRNA ligase activity
F0U64_RS09900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0U64_RS09930	COG2814	Major facilitator Superfamily
F0U64_RS09955	COG0384	phenazine biosynthesis protein PhzF
F0U64_RS09960	COG0456	acetyltransferase
F0U64_RS09995	COG1522	sequence-specific DNA binding
F0U64_RS10025	COG0583	DNA-binding transcription factor activity
F0U64_RS10030	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS10055	COG1116	anion transmembrane transporter activity
F0U64_RS10085	COG5265	(ABC) transporter
F0U64_RS10090	COG0656	L-ascorbic acid biosynthetic process
F0U64_RS10105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0U64_RS10115	COG1917	Cupin 2, conserved barrel domain protein
F0U64_RS10115	COG4977	sequence-specific DNA binding
F0U64_RS10120	COG2223	nitrite transmembrane transporter activity
F0U64_RS10130	COG1215	transferase activity, transferring glycosyl groups
F0U64_RS10135	COG1649	PFAM Uncharacterised BCR, COG1649
F0U64_RS10135	COG0726	polysaccharide deacetylase
F0U64_RS10140	COG0457	Tetratricopeptide repeat
F0U64_RS10170	COG1610	YqeY-like protein
F0U64_RS10175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0U64_RS10180	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS10220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0U64_RS10230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0U64_RS10235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0U64_RS10260	COG1959	2 iron, 2 sulfur cluster binding
F0U64_RS10265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS10270	COG0697	spore germination
F0U64_RS10275	COG0506	proline dehydrogenase activity
F0U64_RS10295	COG0583	DNA-binding transcription factor activity
F0U64_RS10305	COG0625	glutathione transferase activity
F0U64_RS10320	COG2814	Major facilitator Superfamily
F0U64_RS10325	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F0U64_RS10340	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS10345	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS10385	COG3245	cytochrome
F0U64_RS10390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F0U64_RS10405	COG1280	lysine exporter protein (LysE YggA)
F0U64_RS10420	COG0697	spore germination
F0U64_RS10425	COG0697	spore germination
F0U64_RS10440	COG0534	Mate efflux family protein
F0U64_RS10445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F0U64_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS10460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0U64_RS10465	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
F0U64_RS10475	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS10510	COG2207	Transcriptional regulator
F0U64_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS10530	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS10535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_RS10540	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_RS10550	COG1304	FMN binding
F0U64_RS10570	COG3712	iron ion homeostasis
F0U64_RS10575	COG1595	DNA-templated transcription, initiation
F0U64_RS10600	COG3121	Chaperone
F0U64_RS10610	COG2205	protein histidine kinase activity
F0U64_RS10610	COG0784	Response regulator, receiver
F0U64_RS10610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS10610	COG2198	Histidine kinase
F0U64_RS10615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS10615	COG2205	protein histidine kinase activity
F0U64_RS10625	COG5001	Diguanylate cyclase
F0U64_RS10625	COG1716	ATPase activity
F0U64_RS10645	COG3088	subunit of a heme lyase
F0U64_RS10650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_RS10660	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F0U64_RS10680	COG4133	protoheme IX ABC transporter activity
F0U64_RS10700	COG3381	protein complex oligomerization
F0U64_RS10720	COG4235	cytochrome complex assembly
F0U64_RS10730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_RS10740	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F0U64_RS10760	COG4133	protoheme IX ABC transporter activity
F0U64_RS10765	COG3005	denitrification pathway
F0U64_RS10770	COG3043	anaerobic respiration
F0U64_RS10790	COG3246	L-lysine catabolic process to acetate
F0U64_RS10795	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_RS10800	COG0583	DNA-binding transcription factor activity
F0U64_RS10810	COG0129	dihydroxy-acid dehydratase activity
F0U64_RS10815	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS10820	COG5001	Diguanylate cyclase
F0U64_RS10825	COG1024	Enoyl-CoA hydratase
F0U64_RS10855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS10865	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F0U64_RS10870	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS10875	COG0583	DNA-binding transcription factor activity
F0U64_RS10880	COG2610	gluconate transmembrane transporter activity
F0U64_RS10920	COG0235	Class ii aldolase
F0U64_RS10925	COG0477	Major facilitator Superfamily
F0U64_RS10940	COG2188	Transcriptional regulator
F0U64_RS10945	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS10985	COG1280	lysine exporter protein (LysE YggA)
F0U64_RS10990	COG5265	(ABC) transporter
F0U64_RS11000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_RS11015	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS11020	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS11055	COG0583	DNA-binding transcription factor activity
F0U64_RS11065	COG0583	DNA-binding transcription factor activity
F0U64_RS11075	COG0583	DNA-binding transcription factor activity
F0U64_RS11110	COG2814	Major facilitator Superfamily
F0U64_RS11115	COG0154	amidase activity
F0U64_RS11165	COG2070	2-Nitropropane dioxygenase
F0U64_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS11205	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_RS11210	COG0307	riboflavin synthase, alpha
F0U64_RS11220	COG2271	Major facilitator Superfamily
F0U64_RS11230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0U64_RS11240	COG0789	Transcriptional regulator
F0U64_RS11265	COG4774	siderophore transport
F0U64_RS11275	COG0022	dehydrogenase e1 component
F0U64_RS11295	COG1724	mRNA binding
F0U64_RS11300	COG1598	PFAM Uncharacterised protein family UPF0150
F0U64_RS11305	COG0165	Argininosuccinate lyase
F0U64_RS11310	COG0668	transmembrane transport
F0U64_RS11380	COG2165	general secretion pathway protein
F0U64_RS11410	COG0583	DNA-binding transcription factor activity
F0U64_RS11420	COG0747	negative chemotaxis
F0U64_RS11425	COG0601	transmembrane transport
F0U64_RS11430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS11435	COG4172	Belongs to the ABC transporter superfamily
F0U64_RS11440	COG4681	YaeQ
F0U64_RS11455	COG0477	Major facilitator Superfamily
F0U64_RS11460	COG3161	chorismate lyase activity
F0U64_RS11465	COG1187	pseudouridine synthase activity
F0U64_RS11470	COG0583	DNA-binding transcription factor activity
F0U64_RS11495	COG1999	signal sequence binding
F0U64_RS11505	COG0339	signal peptide processing
F0U64_RS11510	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F0U64_RS11515	COG4566	intracellular signal transduction
F0U64_RS11525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F0U64_RS11530	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0U64_RS11535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0U64_RS11545	COG0583	DNA-binding transcription factor activity
F0U64_RS11575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F0U64_RS11585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0U64_RS11595	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
F0U64_RS11605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F0U64_RS11620	COG1191	sigma factor activity
F0U64_RS11640	COG1360	Flagellar Motor Protein
F0U64_RS11645	COG0745	RESPONSE REGULATOR receiver
F0U64_RS11655	COG0835	chemotaxis
F0U64_RS11660	COG0840	transmembrane signaling receptor activity
F0U64_RS11665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F0U64_RS11670	COG2201	protein-glutamate methylesterase activity
F0U64_RS11675	COG0745	RESPONSE REGULATOR receiver
F0U64_RS11680	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
F0U64_RS11685	COG0840	transmembrane signaling receptor activity
F0U64_RS11710	COG2747	anti-sigma28 factor FlgM
F0U64_RS11720	COG1815	bacterial-type flagellum-dependent cell motility
F0U64_RS11725	COG1558	bacterial-type flagellum-dependent cell motility
F0U64_RS11740	COG4787	bacterial-type flagellum-dependent cell motility
F0U64_RS11775	COG0840	transmembrane signaling receptor activity
F0U64_RS11780	COG0840	transmembrane signaling receptor activity
F0U64_RS11790	COG0840	transmembrane signaling receptor activity
F0U64_RS11795	COG0840	transmembrane signaling receptor activity
F0U64_RS11830	COG1580	Controls the rotational direction of flagella during chemotaxis
F0U64_RS11855	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F0U64_RS11860	COG1766	The M ring may be actively involved in energy transduction
F0U64_RS11865	COG1677	Flagellar hook-basal body complex protein FliE
F0U64_RS11875	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F0U64_RS11895	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F0U64_RS11900	COG1334	flagellar protein FlaG
F0U64_RS11905	COG1414	Transcriptional regulator
F0U64_RS11915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS11920	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS11930	COG0285	dihydrofolate synthase activity
F0U64_RS11950	COG1451	nucleotide metabolic process
F0U64_RS11955	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F0U64_RS11965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F0U64_RS11970	COG0024	Methionine aminopeptidase
F0U64_RS11975	COG0052	Belongs to the universal ribosomal protein uS2 family
F0U64_RS11980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F0U64_RS11985	COG0528	UMP kinase activity
F0U64_RS11990	COG0233	cytoplasmic translational termination
F0U64_RS11995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F0U64_RS12005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F0U64_RS12010	COG0750	zinc metalloprotease
F0U64_RS12015	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0U64_RS12020	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
F0U64_RS12025	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0U64_RS12030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0U64_RS12045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F0U64_RS12050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0U64_RS12070	COG2169	Transcriptional regulator
F0U64_RS12070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0U64_RS12075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0U64_RS12075	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_RS12095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F0U64_RS12100	COG2867	negative regulation of translational initiation
F0U64_RS12105	COG2914	Belongs to the UPF0125 (RnfH) family
F0U64_RS12115	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_RS12115	COG1024	Enoyl-CoA hydratase
F0U64_RS12140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F0U64_RS12145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F0U64_RS12150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F0U64_RS12155	COG0084	hydrolase, TatD family'
F0U64_RS12170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS12175	COG0765	amino acid transport
F0U64_RS12180	COG1126	abc transporter atp-binding protein
F0U64_RS12185	COG0010	Belongs to the arginase family
F0U64_RS12195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0U64_RS12205	COG0095	Lipoate-protein ligase
F0U64_RS12220	COG0625	glutathione transferase activity
F0U64_RS12230	COG1522	sequence-specific DNA binding
F0U64_RS12235	COG0386	Belongs to the glutathione peroxidase family
F0U64_RS12240	COG2814	Major facilitator Superfamily
F0U64_RS12260	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F0U64_RS12270	COG0840	transmembrane signaling receptor activity
F0U64_RS12280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS12310	COG1902	pentaerythritol trinitrate reductase activity
F0U64_RS12340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F0U64_RS12355	COG0842	Transport permease protein
F0U64_RS12360	COG1131	(ABC) transporter
F0U64_RS12375	COG2130	NADP-dependent
F0U64_RS12400	COG3842	ATPase activity
F0U64_RS12405	COG3842	ATPase activity
F0U64_RS12415	COG0395	ABC-type sugar transport system, permease component
F0U64_RS12460	COG0346	lactoylglutathione lyase activity
F0U64_RS12465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS12485	COG3634	alkyl hydroperoxide reductase activity
F0U64_RS12490	COG1959	2 iron, 2 sulfur cluster binding
F0U64_RS12500	COG0583	DNA-binding transcription factor activity
F0U64_RS12505	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS12540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS12545	COG0420	3'-5' exonuclease activity
F0U64_RS12575	COG2111	Na H antiporter
F0U64_RS12575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F0U64_RS12580	COG1006	Multisubunit Na H antiporter MnhC subunit
F0U64_RS12585	COG0651	ATP synthesis coupled electron transport
F0U64_RS12590	COG1863	multisubunit Na H antiporter MnhE subunit
F0U64_RS12595	COG2212	antiporter activity
F0U64_RS12600	COG1320	monovalent cation:proton antiporter activity
F0U64_RS12620	COG1619	proteins homologs of microcin C7 resistance protein MccF
F0U64_RS12625	COG0488	(ABC) transporter
F0U64_RS12660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_RS12665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_RS12675	COG2252	PERMEase
F0U64_RS12680	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F0U64_RS12685	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
F0U64_RS12695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F0U64_RS12720	COG0583	DNA-binding transcription factor activity
F0U64_RS12725	COG2814	Major facilitator Superfamily
F0U64_RS12730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0U64_RS12735	COG0789	Transcriptional regulator
F0U64_RS12750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F0U64_RS12750	COG0678	peroxiredoxin activity
F0U64_RS12760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F0U64_RS12765	COG0584	glycerophosphoryl diester phosphodiesterase
F0U64_RS12775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_RS12785	COG4181	ATPase activity
F0U64_RS12795	COG1178	ABC-type Fe3 transport system permease component
F0U64_RS12800	COG3842	ATPase activity
F0U64_RS12805	COG0583	DNA-binding transcription factor activity
F0U64_RS12810	COG0560	Phosphoserine phosphatase
F0U64_RS12825	COG0583	DNA-binding transcription factor activity
F0U64_RS12840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_RS12855	COG0583	DNA-binding transcription factor activity
F0U64_RS12860	COG4336	lyase activity
F0U64_RS12890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS12910	COG2816	NAD+ diphosphatase activity
F0U64_RS12950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS12955	COG0765	amino acid transport
F0U64_RS12960	COG1126	abc transporter atp-binding protein
F0U64_RS12965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0U64_RS12970	COG1758	RNA polymerase activity
F0U64_RS12975	COG0194	GDP metabolic process
F0U64_RS12980	COG3258	Cytochrome c
F0U64_RS12985	COG2863	cytochrome
F0U64_RS12990	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS12995	COG2831	hemolysin activation secretion protein
F0U64_RS13000	COG3210	domain, Protein
F0U64_RS13010	COG0791	NLP P60 protein
F0U64_RS13025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F0U64_RS13030	COG0833	amino acid
F0U64_RS13035	COG1561	YicC-like family, N-terminal region
F0U64_RS13040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F0U64_RS13050	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS13065	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F0U64_RS13070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0U64_RS13075	COG0174	glutamine synthetase
F0U64_RS13090	COG2204	response regulator
F0U64_RS13095	COG0583	DNA-binding transcription factor activity
F0U64_RS13100	COG1741	Belongs to the pirin family
F0U64_RS13105	COG1741	Belongs to the pirin family
F0U64_RS13110	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS13115	COG3842	ATPase activity
F0U64_RS13120	COG4149	molybdate abc transporter
F0U64_RS13125	COG1840	ABC-type Fe3 transport system, periplasmic component
F0U64_RS13135	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS13150	COG0583	DNA-binding transcription factor activity
F0U64_RS13160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F0U64_RS13170	COG0783	Belongs to the Dps family
F0U64_RS13180	COG0457	Tetratricopeptide repeat
F0U64_RS13185	COG0438	transferase activity, transferring glycosyl groups
F0U64_RS13210	COG1560	Kdo2-lipid A biosynthetic process
F0U64_RS13210	COG4783	chaperone-mediated protein folding
F0U64_RS13215	COG3866	Pectate lyase
F0U64_RS13230	COG0745	RESPONSE REGULATOR receiver
F0U64_RS13235	COG2205	protein histidine kinase activity
F0U64_RS13250	COG3842	ATPase activity
F0U64_RS13255	COG0395	ABC-type sugar transport system, permease component
F0U64_RS13260	COG1175	transmembrane transport
F0U64_RS13265	COG1653	transport
F0U64_RS13275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F0U64_RS13290	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS13315	COG1794	racemase activity, acting on amino acids and derivatives
F0U64_RS13320	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_RS13330	COG0583	DNA-binding transcription factor activity
F0U64_RS13335	COG0625	glutathione transferase activity
F0U64_RS13340	COG2133	pyrroloquinoline quinone binding
F0U64_RS13350	COG0697	spore germination
F0U64_RS13355	COG2363	Small membrane protein
F0U64_RS13375	COG0010	Belongs to the arginase family
F0U64_RS13380	COG1464	Belongs to the NlpA lipoprotein family
F0U64_RS13390	COG2814	Major facilitator Superfamily
F0U64_RS13400	COG1408	metallophosphoesterase
F0U64_RS13410	COG0688	phosphatidylethanolamine metabolic process
F0U64_RS13415	COG0488	(ABC) transporter
F0U64_RS13440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS13445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F0U64_RS13450	COG5001	Diguanylate cyclase
F0U64_RS13450	COG3300	MHYT domain
F0U64_RS13465	COG2814	Major facilitator Superfamily
F0U64_RS13490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F0U64_RS13495	COG2204	response regulator
F0U64_RS13530	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS13550	COG0693	protein deglycase activity
F0U64_RS13565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0U64_RS13575	COG1289	transmembrane transporter activity
F0U64_RS13580	COG3300	MHYT domain
F0U64_RS13580	COG5001	Diguanylate cyclase
F0U64_RS13595	COG4774	siderophore transport
F0U64_RS13630	COG1253	flavin adenine dinucleotide binding
F0U64_RS13645	COG2205	protein histidine kinase activity
F0U64_RS13800	COG0789	Transcriptional regulator
F0U64_RS13810	COG3706	GGDEF domain
F0U64_RS13840	COG1116	anion transmembrane transporter activity
F0U64_RS13845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS13850	COG4521	taurine ABC transporter
F0U64_RS13860	COG0165	Argininosuccinate lyase
F0U64_RS13885	COG0793	Belongs to the peptidase S41A family
F0U64_RS13905	COG0628	permease
F0U64_RS13915	COG1619	proteins homologs of microcin C7 resistance protein MccF
F0U64_RS13930	COG0531	amino acid
F0U64_RS13940	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_RS13945	COG4608	Belongs to the ABC transporter superfamily
F0U64_RS13950	COG0444	Belongs to the ABC transporter superfamily
F0U64_RS13960	COG0601	transmembrane transport
F0U64_RS13965	COG0747	negative chemotaxis
F0U64_RS13975	COG0251	oxidation-reduction process
F0U64_RS13995	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0U64_RS14010	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F0U64_RS14025	COG0446	pyridine nucleotide-disulphide oxidoreductase
F0U64_RS14035	COG3971	2-oxopent-4-enoate hydratase activity
F0U64_RS14065	COG0625	glutathione transferase activity
F0U64_RS14080	COG0477	Major facilitator Superfamily
F0U64_RS14090	COG0579	oxidoreductase
F0U64_RS14105	COG0625	glutathione transferase activity
F0U64_RS14120	COG0431	NADPH-dependent FMN reductase
F0U64_RS14130	COG0798	PFAM Bile acid sodium symporter
F0U64_RS14140	COG0640	Transcriptional regulator
F0U64_RS14160	COG0583	DNA-binding transcription factor activity
F0U64_RS14165	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
F0U64_RS14185	COG1126	abc transporter atp-binding protein
F0U64_RS14190	COG0765	amino acid transport
F0U64_RS14195	COG4597	amino acid ABC transporter
F0U64_RS14200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS14205	COG0626	cystathionine gamma-synthase activity
F0U64_RS14210	COG0583	DNA-binding transcription factor activity
F0U64_RS14230	COG0444	Belongs to the ABC transporter superfamily
F0U64_RS14235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS14240	COG0601	transmembrane transport
F0U64_RS14245	COG0747	negative chemotaxis
F0U64_RS14255	COG0583	DNA-binding transcription factor activity
F0U64_RS14260	COG1335	isochorismatase
F0U64_RS14265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0U64_RS14275	COG2358	TRAP transporter, solute receptor (TAXI family
F0U64_RS14280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS14285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS14295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_RS14300	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_RS14300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0U64_RS14310	COG1276	copper resistance
F0U64_RS14330	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS14335	COG3386	PFAM SMP-30 Gluconolaconase
F0U64_RS14340	COG2721	sulfolactate sulfo-lyase activity
F0U64_RS14360	COG0745	RESPONSE REGULATOR receiver
F0U64_RS14370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS14375	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
F0U64_RS14380	COG3842	ATPase activity
F0U64_RS14385	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0U64_RS14400	COG0586	Pfam SNARE associated Golgi protein
F0U64_RS14405	COG0390	transport system, permease component
F0U64_RS14415	COG3486	L-lysine 6-monooxygenase (NADPH) activity
F0U64_RS14460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS14465	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS14470	COG1120	ATPase activity
F0U64_RS14475	COG1126	abc transporter atp-binding protein
F0U64_RS14480	COG0765	amino acid transport
F0U64_RS14485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS14490	COG2070	2-Nitropropane dioxygenase
F0U64_RS14495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_RS14505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0U64_RS14530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F0U64_RS14535	COG0583	DNA-binding transcription factor activity
F0U64_RS14545	COG1846	Transcriptional regulator
F0U64_RS14555	COG4191	Histidine kinase
F0U64_RS14560	COG4566	intracellular signal transduction
F0U64_RS14595	COG0583	DNA-binding transcription factor activity
F0U64_RS14615	COG1126	abc transporter atp-binding protein
F0U64_RS14625	COG0765	amino acid transport
F0U64_RS14630	COG0436	Aminotransferase
F0U64_RS14655	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
F0U64_RS14680	COG0251	oxidation-reduction process
F0U64_RS14720	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_RS14730	COG1802	Transcriptional regulator
F0U64_RS14735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_RS14755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_RS14780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS14785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_RS14790	COG1116	anion transmembrane transporter activity
F0U64_RS14825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS14830	COG4597	amino acid ABC transporter
F0U64_RS14835	COG3154	lipid carrier protein
F0U64_RS14840	COG0826	peptidase U32
F0U64_RS14845	COG0826	peptidase U32
F0U64_RS14850	COG2197	response regulator
F0U64_RS14855	COG3850	Histidine kinase
F0U64_RS14860	COG1763	Mo-molybdopterin cofactor biosynthetic process
F0U64_RS14865	COG0288	reversible hydration of carbon dioxide
F0U64_RS14870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F0U64_RS14875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_RS14880	COG2181	nitrate reductase activity
F0U64_RS14885	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F0U64_RS14890	COG1140	nitrate reductase beta subunit
F0U64_RS14895	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F0U64_RS14900	COG2223	nitrite transmembrane transporter activity
F0U64_RS14925	COG0583	DNA-binding transcription factor activity
F0U64_RS14945	COG0583	DNA-binding transcription factor activity
F0U64_RS14955	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS14985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS15005	COG2070	2-Nitropropane dioxygenase
F0U64_RS15020	COG5002	protein histidine kinase activity
F0U64_RS15025	COG0745	RESPONSE REGULATOR receiver
F0U64_RS15030	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
F0U64_RS15035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F0U64_RS15045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0U64_RS15050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0U64_RS15065	COG0783	Belongs to the Dps family
F0U64_RS15095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS15100	COG0697	spore germination
F0U64_RS15105	COG2879	small protein
F0U64_RS15110	COG1966	Carbon starvation protein
F0U64_RS15135	COG0583	DNA-binding transcription factor activity
F0U64_RS15140	COG4521	taurine ABC transporter
F0U64_RS15145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F0U64_RS15150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS15185	COG3712	iron ion homeostasis
F0U64_RS15190	COG1595	DNA-templated transcription, initiation
F0U64_RS15195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS15200	COG3210	domain, Protein
F0U64_RS15200	COG3468	outer membrane autotransporter barrel domain protein
F0U64_RS15215	COG0235	Class ii aldolase
F0U64_RS15220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS15230	COG0523	cobalamin synthesis protein
F0U64_RS15235	COG1228	amidohydrolase
F0U64_RS15240	COG4172	Belongs to the ABC transporter superfamily
F0U64_RS15245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS15250	COG0601	transmembrane transport
F0U64_RS15255	COG0747	negative chemotaxis
F0U64_RS15270	COG1414	Transcriptional regulator
F0U64_RS15275	COG0513	Belongs to the DEAD box helicase family
F0U64_RS15280	COG0602	queuosine metabolic process
F0U64_RS15285	COG0720	synthase
F0U64_RS15295	COG1289	transmembrane transporter activity
F0U64_RS15305	COG1566	PFAM secretion protein HlyD family protein
F0U64_RS15320	COG0028	Belongs to the TPP enzyme family
F0U64_RS15330	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS15340	COG0400	carboxylic ester hydrolase activity
F0U64_RS15345	COG0833	amino acid
F0U64_RS15365	COG0587	DNA-directed DNA polymerase activity
F0U64_RS15385	COG0667	Aldo Keto reductase
F0U64_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS15395	COG0583	DNA-binding transcription factor activity
F0U64_RS15420	COG0765	amino acid transport
F0U64_RS15425	COG0765	amino acid transport
F0U64_RS15430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS15435	COG0436	Aminotransferase
F0U64_RS15440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_RS15455	COG3328	transposase activity
F0U64_RS15475	COG3038	cytochrome b561
F0U64_RS15510	COG0840	transmembrane signaling receptor activity
F0U64_RS15595	COG2764	glyoxalase bleomycin resistance protein dioxygenase
F0U64_RS15615	COG4774	siderophore transport
F0U64_RS15620	COG2345	Transcriptional regulator
F0U64_RS15630	COG1414	Transcriptional regulator
F0U64_RS15640	COG0477	Major facilitator Superfamily
F0U64_RS15645	COG0667	Aldo Keto reductase
F0U64_RS15655	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS15660	COG1309	transcriptional regulator
F0U64_RS15680	COG1683	Conserved Protein
F0U64_RS15690	COG2207	Transcriptional regulator
F0U64_RS15710	COG3047	cAMP biosynthetic process
F0U64_RS15710	COG2885	chlorophyll binding
F0U64_RS15725	COG3795	YCII-related domain
F0U64_RS15730	COG3795	YCII-related domain
F0U64_RS15740	COG4941	Belongs to the sigma-70 factor family
F0U64_RS15750	COG0697	spore germination
F0U64_RS15760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0U64_RS15770	COG0583	DNA-binding transcription factor activity
F0U64_RS15800	COG1846	Transcriptional regulator
F0U64_RS15805	COG3541	Predicted nucleotidyltransferase
F0U64_RS15825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS15865	COG1360	Flagellar Motor Protein
F0U64_RS15875	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
F0U64_RS16065	COG0625	glutathione transferase activity
F0U64_RS16070	COG2032	superoxide dismutase activity
F0U64_RS16075	COG2733	membrane
F0U64_RS16085	COG0148	phosphopyruvate hydratase activity
F0U64_RS16110	COG0583	DNA-binding transcription factor activity
F0U64_RS16120	COG0183	Belongs to the thiolase family
F0U64_RS16125	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS16130	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS16135	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS16145	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F0U64_RS16160	COG0583	DNA-binding transcription factor activity
F0U64_RS16170	COG1846	Transcriptional regulator
F0U64_RS16175	COG0477	Major facilitator Superfamily
F0U64_RS16180	COG2010	Cytochrome c
F0U64_RS16180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F0U64_RS16185	COG2080	2 iron, 2 sulfur cluster binding
F0U64_RS16195	COG0596	Alpha beta hydrolase
F0U64_RS16200	COG2309	aminopeptidase activity
F0U64_RS16205	COG1335	isochorismatase
F0U64_RS16210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F0U64_RS16210	COG2010	Cytochrome c
F0U64_RS16220	COG1522	sequence-specific DNA binding
F0U64_RS16225	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS16230	COG3842	ATPase activity
F0U64_RS16235	COG1840	ABC-type Fe3 transport system, periplasmic component
F0U64_RS16240	COG4149	molybdate abc transporter
F0U64_RS16245	COG5001	Diguanylate cyclase
F0U64_RS16245	COG4251	negative regulation of phosphorylation
F0U64_RS16245	COG2203	Gaf domain
F0U64_RS16245	COG3706	GGDEF domain
F0U64_RS16250	COG2201	protein-glutamate methylesterase activity
F0U64_RS16275	COG0840	transmembrane signaling receptor activity
F0U64_RS16295	COG0583	DNA-binding transcription factor activity
F0U64_RS16325	COG0456	acetyltransferase
F0U64_RS16340	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS16375	COG0477	Major facilitator Superfamily
F0U64_RS16410	COG0165	Argininosuccinate lyase
F0U64_RS16425	COG0583	DNA-binding transcription factor activity
F0U64_RS16440	COG2205	protein histidine kinase activity
F0U64_RS16460	COG2207	Transcriptional regulator
F0U64_RS16465	COG2267	carboxylic ester hydrolase activity
F0U64_RS16475	COG4221	oxidoreductase activity
F0U64_RS16480	COG2207	Transcriptional regulator
F0U64_RS16510	COG0640	Transcriptional regulator
F0U64_RS16515	COG0640	Transcriptional regulator
F0U64_RS16525	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F0U64_RS16530	COG0583	DNA-binding transcription factor activity
F0U64_RS16535	COG0431	NADPH-dependent FMN reductase
F0U64_RS16570	COG4264	IucA IucC family
F0U64_RS16605	COG1074	ATP-dependent DNA helicase activity
F0U64_RS16615	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_RS16615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0U64_RS16645	COG0583	DNA-binding transcription factor activity
F0U64_RS16655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0U64_RS16675	COG0583	DNA-binding transcription factor activity
F0U64_RS16680	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS16725	COG2072	flavoprotein involved in K transport
F0U64_RS16730	COG0601	transmembrane transport
F0U64_RS16735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS16745	COG4608	Belongs to the ABC transporter superfamily
F0U64_RS16750	COG0747	negative chemotaxis
F0U64_RS16765	COG0583	DNA-binding transcription factor activity
F0U64_RS16770	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS16775	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F0U64_RS16780	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS16840	COG4774	siderophore transport
F0U64_RS16865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0U64_RS16890	COG0583	DNA-binding transcription factor activity
F0U64_RS16945	COG5001	Diguanylate cyclase
F0U64_RS16950	COG4774	siderophore transport
F0U64_RS16965	COG0583	DNA-binding transcription factor activity
F0U64_RS17015	COG1953	Uracil, thiamine, allantoin
F0U64_RS17050	COG0583	DNA-binding transcription factor activity
F0U64_RS17055	COG2205	protein histidine kinase activity
F0U64_RS17055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS17055	COG2198	Histidine kinase
F0U64_RS17055	COG0784	Response regulator, receiver
F0U64_RS17060	COG0745	RESPONSE REGULATOR receiver
F0U64_RS17060	COG2205	protein histidine kinase activity
F0U64_RS17060	COG3292	Two component regulator propeller
F0U64_RS17085	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS17090	COG0583	DNA-binding transcription factor activity
F0U64_RS17095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS17115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0U64_RS17130	COG0583	DNA-binding transcription factor activity
F0U64_RS17145	COG0642	Histidine kinase
F0U64_RS17170	COG1595	DNA-templated transcription, initiation
F0U64_RS17175	COG3712	iron ion homeostasis
F0U64_RS17180	COG4774	siderophore transport
F0U64_RS17185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F0U64_RS17185	COG0047	phosphoribosylformylglycinamidine synthase activity
F0U64_RS17195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_RS17195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F0U64_RS17200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_RS17235	COG0613	PHP domain protein
F0U64_RS17250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F0U64_RS17260	COG0583	DNA-binding transcription factor activity
F0U64_RS17270	COG0583	DNA-binding transcription factor activity
F0U64_RS17275	COG0477	Major facilitator Superfamily
F0U64_RS17280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0U64_RS17290	COG0159	tryptophan synthase activity
F0U64_RS17315	COG0277	FAD linked oxidase domain protein
F0U64_RS17320	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS17330	COG3119	arylsulfatase activity
F0U64_RS17365	COG2149	membrane
F0U64_RS17375	COG3093	addiction module antidote protein HigA
F0U64_RS17400	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0U64_RS17410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F0U64_RS17415	COG0459	protein refolding
F0U64_RS17450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0U64_RS17455	COG0714	Associated with various cellular activities
F0U64_RS17475	COG2304	oxidoreductase activity
F0U64_RS17490	COG3119	arylsulfatase activity
F0U64_RS17500	COG1280	lysine exporter protein (LysE YggA)
F0U64_RS17530	COG0633	Ferredoxin
F0U64_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS17545	COG4133	protoheme IX ABC transporter activity
F0U64_RS17550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F0U64_RS17590	COG4604	ABC transporter, ATP-binding protein
F0U64_RS17595	COG4605	iron ion homeostasis
F0U64_RS17600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS17605	COG4607	ABC-type enterochelin transport system periplasmic component
F0U64_RS17610	COG4771	TonB-dependent receptor
F0U64_RS17615	COG0745	RESPONSE REGULATOR receiver
F0U64_RS17625	COG0084	hydrolase, TatD family'
F0U64_RS17630	COG1136	(ABC) transporter
F0U64_RS17655	COG2271	Major facilitator Superfamily
F0U64_RS17665	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS17670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F0U64_RS17685	COG3135	benzoate transporter
F0U64_RS17690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F0U64_RS17695	COG1309	transcriptional regulator
F0U64_RS17700	COG0183	Belongs to the thiolase family
F0U64_RS17705	COG1022	Amp-dependent synthetase and ligase
F0U64_RS17735	COG1024	Enoyl-CoA hydratase
F0U64_RS17745	COG1803	Methylglyoxal synthase
F0U64_RS17750	COG2975	iron-sulfur cluster assembly
F0U64_RS17755	COG0633	Ferredoxin
F0U64_RS17760	COG0443	Heat shock 70 kDa protein
F0U64_RS17765	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F0U64_RS17770	COG0316	Belongs to the HesB IscA family
F0U64_RS17775	COG0822	iron-sulfur transferase activity
F0U64_RS17780	COG1104	cysteine desulfurase activity
F0U64_RS17790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F0U64_RS17795	COG0556	nucleotide-excision repair
F0U64_RS17805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F0U64_RS17810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F0U64_RS17815	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F0U64_RS17820	COG0740	serine-type endopeptidase activity
F0U64_RS17825	COG0544	peptidyl-prolyl cis-trans isomerase activity
F0U64_RS17830	COG0501	Belongs to the peptidase M48B family
F0U64_RS17840	COG1278	Cold shock
F0U64_RS17850	COG1278	Cold shock
F0U64_RS17875	COG0251	oxidation-reduction process
F0U64_RS17885	COG0583	DNA-binding transcription factor activity
F0U64_RS17920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F0U64_RS17945	COG0277	FAD linked oxidase domain protein
F0U64_RS17955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F0U64_RS17960	COG2814	Major facilitator Superfamily
F0U64_RS17995	COG2171	N-acyltransferase activity
F0U64_RS18005	COG2890	protein-(glutamine-N5) methyltransferase activity
F0U64_RS18010	COG0488	(ABC) transporter
F0U64_RS18025	COG4771	TonB-dependent receptor
F0U64_RS18030	COG4771	TonB-dependent receptor
F0U64_RS18035	COG4771	TonB-dependent receptor
F0U64_RS18045	COG1858	cytochrome C peroxidase
F0U64_RS18055	COG0210	DNA helicase
F0U64_RS18070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F0U64_RS18070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0U64_RS18075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F0U64_RS18080	COG0196	riboflavin kinase activity
F0U64_RS18085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F0U64_RS18090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F0U64_RS18095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F0U64_RS18145	COG1902	pentaerythritol trinitrate reductase activity
F0U64_RS18150	COG1126	abc transporter atp-binding protein
F0U64_RS18155	COG0765	amino acid transport
F0U64_RS18160	COG0765	amino acid transport
F0U64_RS18165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS18180	COG1764	response to oxidative stress
F0U64_RS18190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_RS18195	COG0625	glutathione transferase activity
F0U64_RS18205	COG4178	(ABC) transporter
F0U64_RS18210	COG4771	TonB-dependent receptor
F0U64_RS18225	COG2271	Major facilitator Superfamily
F0U64_RS18255	COG0506	proline dehydrogenase activity
F0U64_RS18255	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F0U64_RS18255	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F0U64_RS18265	COG3008	intermembrane lipid transfer
F0U64_RS18270	COG2995	paraquat-inducible protein a
F0U64_RS18280	COG4953	penicillin-binding protein 1C
F0U64_RS18285	COG2373	Large extracellular alpha-helical protein
F0U64_RS18290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F0U64_RS18295	COG1278	Cold shock
F0U64_RS18305	COG0183	Belongs to the thiolase family
F0U64_RS18310	COG0038	chloride channel
F0U64_RS18320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F0U64_RS18330	COG1570	exodeoxyribonuclease VII activity
F0U64_RS18335	COG0811	peptide transport
F0U64_RS18345	COG1663	tetraacyldisaccharide 4'-kinase activity
F0U64_RS18355	COG2835	tetraacyldisaccharide 4'-kinase activity
F0U64_RS18360	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F0U64_RS18365	COG0563	adenylate kinase activity
F0U64_RS18375	COG0728	peptidoglycan biosynthetic process
F0U64_RS18385	COG0268	Binds directly to 16S ribosomal RNA
F0U64_RS18390	COG0583	DNA-binding transcription factor activity
F0U64_RS18405	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS18410	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F0U64_RS18415	COG2186	Transcriptional regulator
F0U64_RS18425	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS18435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0U64_RS18465	COG3384	dioxygenase
F0U64_RS18470	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_RS18485	COG3971	2-oxopent-4-enoate hydratase activity
F0U64_RS18495	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS18500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0U64_RS18505	COG1562	ergosterol biosynthetic process
F0U64_RS18510	COG1562	ergosterol biosynthetic process
F0U64_RS18520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0U64_RS18535	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_RS18550	COG5564	TIM-barrel signal transduction protein
F0U64_RS18555	COG5441	Belongs to the UPF0261 family
F0U64_RS18580	COG0542	response to heat
F0U64_RS18590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0U64_RS18600	COG0477	Major facilitator Superfamily
F0U64_RS18620	COG0494	nUDIX hydrolase
F0U64_RS18630	COG0583	DNA-binding transcription factor activity
F0U64_RS18635	COG0443	Heat shock 70 kDa protein
F0U64_RS18670	COG2814	Major facilitator Superfamily
F0U64_RS18680	COG3530	Putative quorum-sensing-regulated virulence factor
F0U64_RS18695	COG0625	glutathione transferase activity
F0U64_RS18720	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS18730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0U64_RS18790	COG1522	sequence-specific DNA binding
F0U64_RS18800	COG4172	Belongs to the ABC transporter superfamily
F0U64_RS18815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS18825	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_RS18840	COG1595	DNA-templated transcription, initiation
F0U64_RS18860	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_RS18870	COG2951	lytic endotransglycosylase activity
F0U64_RS18880	COG0583	DNA-binding transcription factor activity
F0U64_RS18890	COG2272	Belongs to the type-B carboxylesterase lipase family
F0U64_RS18895	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS18900	COG1309	transcriptional regulator
F0U64_RS18910	COG1473	amidohydrolase
F0U64_RS18920	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
F0U64_RS18935	COG3618	amidohydrolase
F0U64_RS18940	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS18975	COG2011	ABC-type metal ion transport system permease component
F0U64_RS18980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F0U64_RS18985	COG1464	Belongs to the NlpA lipoprotein family
F0U64_RS18995	COG2814	Major facilitator Superfamily
F0U64_RS19005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F0U64_RS19010	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_RS19050	COG2837	iron assimilation
F0U64_RS19075	COG0583	DNA-binding transcription factor activity
F0U64_RS19080	COG2814	Major facilitator Superfamily
F0U64_RS19085	COG2169	Transcriptional regulator
F0U64_RS19115	COG1272	protein, Hemolysin III
F0U64_RS19125	COG1278	Cold shock
F0U64_RS19155	COG4638	Rieske (2fe-2S)
F0U64_RS19170	COG3321	synthase
F0U64_RS19170	COG0604	alcohol dehydrogenase
F0U64_RS19180	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS19185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_RS19210	COG0183	Belongs to the thiolase family
F0U64_RS19225	COG0842	Transport permease protein
F0U64_RS19230	COG1131	(ABC) transporter
F0U64_RS19250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_RS19280	COG0811	peptide transport
F0U64_RS19340	COG1396	sequence-specific DNA binding
F0U64_RS19355	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS19395	COG1024	Enoyl-CoA hydratase
F0U64_RS19410	COG0583	DNA-binding transcription factor activity
F0U64_RS19465	COG3384	dioxygenase
F0U64_RS19495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_RS19500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F0U64_RS19505	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F0U64_RS19520	COG1609	Transcriptional regulator
F0U64_RS19525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_RS19530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_RS19540	COG1850	ribulose-bisphosphate carboxylase activity
F0U64_RS19555	COG0505	Belongs to the CarA family
F0U64_RS19575	COG3608	succinylglutamate desuccinylase aspartoacylase
F0U64_RS19575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F0U64_RS19580	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F0U64_RS19595	COG2207	Transcriptional regulator
F0U64_RS19600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS19690	COG2192	nodulation
F0U64_RS19700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F0U64_RS19705	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS19710	COG0438	transferase activity, transferring glycosyl groups
F0U64_RS19720	COG5265	(ABC) transporter
F0U64_RS19740	COG0668	transmembrane transport
F0U64_RS19750	COG0166	Belongs to the GPI family
F0U64_RS19760	COG3685	Protein conserved in bacteria
F0U64_RS19780	COG0387	Pfam Sodium calcium exchanger
F0U64_RS19785	COG3568	Endonuclease Exonuclease Phosphatase
F0U64_RS19790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0U64_RS19795	COG0392	lysyltransferase activity
F0U64_RS19800	COG0297	glycogen (starch) synthase activity
F0U64_RS19805	COG0366	Alpha amylase catalytic
F0U64_RS19810	COG0366	Alpha amylase catalytic
F0U64_RS19825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F0U64_RS19830	COG1640	4-alpha-glucanotransferase
F0U64_RS19840	COG1113	amino acid transport
F0U64_RS19855	COG1546	Belongs to the CinA family
F0U64_RS19855	COG1058	Belongs to the CinA family
F0U64_RS19860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0U64_RS19870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F0U64_RS19880	COG0477	Major facilitator Superfamily
F0U64_RS19885	COG1595	DNA-templated transcription, initiation
F0U64_RS19895	COG4774	siderophore transport
F0U64_RS19905	COG4771	TonB-dependent receptor
F0U64_RS19920	COG1120	ATPase activity
F0U64_RS19925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS19955	COG0596	Alpha beta hydrolase
F0U64_RS19970	COG1414	Transcriptional regulator
F0U64_RS19975	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0U64_RS19980	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS19990	COG2721	sulfolactate sulfo-lyase activity
F0U64_RS20000	COG0765	amino acid transport
F0U64_RS20015	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_RS20025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0U64_RS20030	COG3958	Transketolase
F0U64_RS20035	COG3959	Transketolase, thiamine diphosphate binding domain
F0U64_RS20040	COG1802	Transcriptional regulator
F0U64_RS20045	COG0371	Dehydrogenase
F0U64_RS20050	COG3246	L-lysine catabolic process to acetate
F0U64_RS20055	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_RS20060	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS20070	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS20085	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS20085	COG0604	alcohol dehydrogenase
F0U64_RS20085	COG3321	synthase
F0U64_RS20090	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS20120	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS20125	COG0583	DNA-binding transcription factor activity
F0U64_RS20130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F0U64_RS20155	COG2814	Major facilitator Superfamily
F0U64_RS20170	COG3384	dioxygenase
F0U64_RS20185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F0U64_RS20240	COG4964	Belongs to the GSP D family
F0U64_RS20285	COG1846	Transcriptional regulator
F0U64_RS20290	COG4172	Belongs to the ABC transporter superfamily
F0U64_RS20295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS20300	COG0601	transmembrane transport
F0U64_RS20315	COG0598	Magnesium transport protein CorA
F0U64_RS20335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F0U64_RS20350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F0U64_RS20355	COG1045	serine acetyltransferase
F0U64_RS20360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F0U64_RS20365	COG0166	Belongs to the GPI family
F0U64_RS20370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0U64_RS20375	COG3206	protein involved in exopolysaccharide biosynthesis
F0U64_RS20375	COG0489	protein tyrosine kinase activity
F0U64_RS20380	COG1596	polysaccharide export
F0U64_RS20390	COG1051	belongs to the nudix hydrolase family
F0U64_RS20410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_RS20435	COG0463	Glycosyl transferase, family 2
F0U64_RS20440	COG0110	maltose O-acetyltransferase activity
F0U64_RS20445	COG0297	glycogen (starch) synthase activity
F0U64_RS20450	COG2197	response regulator
F0U64_RS20455	COG2197	response regulator
F0U64_RS20465	COG1309	transcriptional regulator
F0U64_RS20470	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS20480	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_RS20480	COG1024	Enoyl-CoA hydratase
F0U64_RS20490	COG1024	Enoyl-CoA hydratase
F0U64_RS20490	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_RS20495	COG0183	Belongs to the thiolase family
F0U64_RS20510	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS20520	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS20530	COG1132	(ABC) transporter
F0U64_RS20540	COG3395	kinase activity
F0U64_RS20545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F0U64_RS20555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0U64_RS20560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F0U64_RS20565	COG1024	Enoyl-CoA hydratase
F0U64_RS20575	COG1414	Transcriptional regulator
F0U64_RS20585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F0U64_RS20605	COG0583	DNA-binding transcription factor activity
F0U64_RS20635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F0U64_RS20640	COG1309	transcriptional regulator
F0U64_RS20650	COG1051	belongs to the nudix hydrolase family
F0U64_RS20655	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
F0U64_RS20665	COG0784	Response regulator, receiver
F0U64_RS20665	COG2205	protein histidine kinase activity
F0U64_RS20675	COG0784	Response regulator, receiver
F0U64_RS20675	COG2205	protein histidine kinase activity
F0U64_RS20690	COG2863	cytochrome
F0U64_RS20695	COG3258	Cytochrome c
F0U64_RS20710	COG3278	Belongs to the heme-copper respiratory oxidase family
F0U64_RS20730	COG0348	domain, Protein
F0U64_RS20770	COG0527	aspartate kinase activity
F0U64_RS20775	COG0037	tRNA processing
F0U64_RS20780	COG0825	malonyl-CoA metabolic process
F0U64_RS20790	COG0215	cysteine-tRNA ligase activity
F0U64_RS20805	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0U64_RS20810	COG1968	undecaprenyl-diphosphatase activity
F0U64_RS20815	COG1253	flavin adenine dinucleotide binding
F0U64_RS20830	COG4263	nitrous-oxide reductase activity
F0U64_RS20845	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
F0U64_RS20855	COG1477	protein flavinylation
F0U64_RS20860	COG4804	nuclease activity
F0U64_RS20865	COG0483	inositol monophosphate 1-phosphatase activity
F0U64_RS20885	COG0668	transmembrane transport
F0U64_RS20925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_RS20930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS20935	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F0U64_RS20970	COG3360	Dodecin
F0U64_RS20980	COG0583	DNA-binding transcription factor activity
F0U64_RS20985	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS21045	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F0U64_RS21050	COG2850	peptidyl-arginine hydroxylation
F0U64_RS21060	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F0U64_RS21065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_RS21070	COG1994	Peptidase M50
F0U64_RS21075	COG0009	L-threonylcarbamoyladenylate synthase
F0U64_RS21080	COG2321	neutral zinc metallopeptidase
F0U64_RS21135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0U64_RS21140	COG3969	phosphoadenosine phosphosulfate
F0U64_RS21150	COG1475	DNA binding
F0U64_RS21155	COG0642	Histidine kinase
F0U64_RS21175	COG3188	usher protein
F0U64_RS21180	COG3121	Chaperone
F0U64_RS21190	COG5001	Diguanylate cyclase
F0U64_RS21190	COG3300	MHYT domain
F0U64_RS21200	COG2197	response regulator
F0U64_RS21230	COG3121	Chaperone
F0U64_RS21235	COG3188	usher protein
F0U64_RS21280	COG3387	PFAM Glycoside hydrolase 15-related
F0U64_RS21295	COG0840	transmembrane signaling receptor activity
F0U64_RS21300	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS21305	COG1280	lysine exporter protein (LysE YggA)
F0U64_RS21310	COG1522	sequence-specific DNA binding
F0U64_RS21315	COG1280	lysine exporter protein (LysE YggA)
F0U64_RS21395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0U64_RS21405	COG1917	Cupin 2, conserved barrel domain protein
F0U64_RS21405	COG2207	Transcriptional regulator
F0U64_RS21415	COG2084	Dehydrogenase
F0U64_RS21430	COG1802	Transcriptional regulator
F0U64_RS21445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_RS21470	COG2205	protein histidine kinase activity
F0U64_RS21475	COG1764	response to oxidative stress
F0U64_RS21480	COG0583	DNA-binding transcription factor activity
F0U64_RS21485	COG0601	transmembrane transport
F0U64_RS21490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS21495	COG0444	Belongs to the ABC transporter superfamily
F0U64_RS21500	COG4608	Belongs to the ABC transporter superfamily
F0U64_RS21515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS21520	COG0586	Pfam SNARE associated Golgi protein
F0U64_RS21525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS21530	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F0U64_RS21590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS21595	COG0765	amino acid transport
F0U64_RS21605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS21615	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_RS21640	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS21660	COG0348	domain, Protein
F0U64_RS21680	COG3278	Belongs to the heme-copper respiratory oxidase family
F0U64_RS21695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0U64_RS21700	COG0156	8-amino-7-oxononanoate synthase activity
F0U64_RS21725	COG2224	Isocitrate lyase
F0U64_RS21730	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F0U64_RS21730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F0U64_RS21735	COG1858	cytochrome C peroxidase
F0U64_RS21740	COG0583	DNA-binding transcription factor activity
F0U64_RS21745	COG0473	3-isopropylmalate dehydrogenase activity
F0U64_RS21755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F0U64_RS21770	COG0736	holo-[acyl-carrier-protein] synthase activity
F0U64_RS21775	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F0U64_RS21785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_RS21790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_RS21815	COG3842	ATPase activity
F0U64_RS21820	COG4149	molybdate abc transporter
F0U64_RS21825	COG0725	ABC transporter, periplasmic molybdate-binding protein
F0U64_RS21830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
F0U64_RS21850	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
F0U64_RS21860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_RS21870	COG4120	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS21880	COG0667	Aldo Keto reductase
F0U64_RS21890	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS21895	COG1024	Enoyl-CoA hydratase
F0U64_RS21905	COG1802	Transcriptional regulator
F0U64_RS21915	COG0183	Belongs to the thiolase family
F0U64_RS21920	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS21925	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS21930	COG0583	DNA-binding transcription factor activity
F0U64_RS21955	COG4213	ABC transporter substrate-binding protein
F0U64_RS21960	COG1129	ABC transporter
F0U64_RS21965	COG4214	carbohydrate transport
F0U64_RS21970	COG2706	6-phosphogluconolactonase activity
F0U64_RS21975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_RS21990	COG4175	Glycine betaine
F0U64_RS21990	COG3448	diguanylate cyclase activity
F0U64_RS21995	COG4176	ABC-type proline glycine betaine transport system permease component
F0U64_RS22005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F0U64_RS22010	COG2814	Major facilitator Superfamily
F0U64_RS22015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F0U64_RS22020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F0U64_RS22055	COG1686	Belongs to the peptidase S11 family
F0U64_RS22070	COG1846	Transcriptional regulator
F0U64_RS22075	COG2814	Major facilitator Superfamily
F0U64_RS22080	COG0495	leucyl-tRNA aminoacylation
F0U64_RS22095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
F0U64_RS22115	COG0154	amidase activity
F0U64_RS22125	COG0477	Major facilitator Superfamily
F0U64_RS22135	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_RS22150	COG0583	DNA-binding transcription factor activity
F0U64_RS22200	COG0583	DNA-binding transcription factor activity
F0U64_RS22205	COG0427	acetyl-CoA hydrolase
F0U64_RS22210	COG0583	DNA-binding transcription factor activity
F0U64_RS22215	COG3264	Mechanosensitive ion channel
F0U64_RS22215	COG1511	domain protein
F0U64_RS22265	COG3842	ATPase activity
F0U64_RS22270	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_RS22275	COG1177	transmembrane transport
F0U64_RS22280	COG3938	Belongs to the proline racemase family
F0U64_RS22295	COG0517	IMP dehydrogenase activity
F0U64_RS22325	COG0500	methyltransferase
F0U64_RS22340	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F0U64_RS22355	COG0667	Aldo Keto reductase
F0U64_RS22360	COG2207	Transcriptional regulator
F0U64_RS22365	COG0583	DNA-binding transcription factor activity
F0U64_RS22370	COG1335	isochorismatase
F0U64_RS22380	COG2841	Protein conserved in bacteria
F0U64_RS22395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0U64_RS22400	COG0438	transferase activity, transferring glycosyl groups
F0U64_RS22460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F0U64_RS22480	COG2814	Major facilitator Superfamily
F0U64_RS22485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F0U64_RS22510	COG0248	Ppx GppA phosphatase
F0U64_RS22520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0U64_RS22530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0U64_RS22535	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F0U64_RS22540	COG1534	Rna-binding protein
F0U64_RS22545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0U64_RS22550	COG0840	transmembrane signaling receptor activity
F0U64_RS22555	COG2233	PERMEase
F0U64_RS22575	COG3842	ATPase activity
F0U64_RS22590	COG4221	oxidoreductase activity
F0U64_RS22600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F0U64_RS22605	COG0505	Belongs to the CarA family
F0U64_RS22625	COG0745	RESPONSE REGULATOR receiver
F0U64_RS22640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS22650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_RS22655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS22670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F0U64_RS22680	COG1074	ATP-dependent DNA helicase activity
F0U64_RS22695	COG2070	2-Nitropropane dioxygenase
F0U64_RS22715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS22730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0U64_RS22735	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS22755	COG1686	Belongs to the peptidase S11 family
F0U64_RS22770	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
F0U64_RS22775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F0U64_RS22780	COG4974	Belongs to the 'phage' integrase family
F0U64_RS22785	COG0583	DNA-binding transcription factor activity
F0U64_RS22790	COG0028	Belongs to the TPP enzyme family
F0U64_RS22835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0U64_RS22880	COG0028	Belongs to the TPP enzyme family
F0U64_RS22885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS22900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0U64_RS22905	COG1414	Transcriptional regulator
F0U64_RS22910	COG0009	L-threonylcarbamoyladenylate synthase
F0U64_RS22915	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F0U64_RS22920	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F0U64_RS22925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F0U64_RS22935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F0U64_RS22955	COG1301	dicarboxylic acid transport
F0U64_RS22965	COG3454	Phosphonate metabolism
F0U64_RS22970	COG4778	phosphonate C-P lyase system protein PhnL
F0U64_RS22975	COG4107	phosphonate C-P lyase system protein PhnK
F0U64_RS22980	COG3627	carbon phosphorus lyase activity
F0U64_RS22985	COG3626	phosphonate metabolism
F0U64_RS22990	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F0U64_RS22995	COG3624	Phosphonate C-P lyase system protein PhnG
F0U64_RS23000	COG2188	Transcriptional regulator
F0U64_RS23005	COG3454	Phosphonate metabolism
F0U64_RS23010	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F0U64_RS23015	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F0U64_RS23020	COG0583	DNA-binding transcription factor activity
F0U64_RS23025	COG0405	Gamma-glutamyltransferase
F0U64_RS23040	COG3639	organic phosphonate transmembrane transporter activity
F0U64_RS23045	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F0U64_RS23050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F0U64_RS23060	COG0640	Transcriptional regulator
F0U64_RS23070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F0U64_RS23080	COG0739	heme binding
F0U64_RS23090	COG0521	Mo-molybdopterin cofactor biosynthetic process
F0U64_RS23100	COG0306	phosphate transporter
F0U64_RS23135	COG0625	glutathione transferase activity
F0U64_RS23155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F0U64_RS23160	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F0U64_RS23175	COG0126	phosphoglycerate kinase activity
F0U64_RS23180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F0U64_RS23185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F0U64_RS23195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F0U64_RS23200	COG2732	(Barnase) inhibitor
F0U64_RS23210	COG0280	phosphate acetyltransferase
F0U64_RS23210	COG0281	malic enzyme
F0U64_RS23220	COG0436	Aminotransferase
F0U64_RS23240	COG0753	catalase activity
F0U64_RS23250	COG0741	lytic transglycosylase activity
F0U64_RS23255	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F0U64_RS23270	COG4575	ribosome binding
F0U64_RS23280	COG1116	anion transmembrane transporter activity
F0U64_RS23285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_RS23290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_RS23295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F0U64_RS23295	COG1648	precorrin-2 dehydrogenase activity
F0U64_RS23300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F0U64_RS23305	COG2027	D-alanyl-D-alanine carboxypeptidase
F0U64_RS23320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_RS23330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F0U64_RS23335	COG0343	queuine tRNA-ribosyltransferase activity
F0U64_RS23345	COG3077	Addiction module antitoxin, RelB DinJ family
F0U64_RS23350	COG1862	Preprotein translocase
F0U64_RS23355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0U64_RS23360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0U64_RS23380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0U64_RS23390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0U64_RS23395	COG1702	phosphate starvation-inducible protein PhoH
F0U64_RS23400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F0U64_RS23405	COG4535	Mg2 and Co2 transporter CorC
F0U64_RS23410	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F0U64_RS23415	COG0667	Aldo Keto reductase
F0U64_RS23460	COG0697	spore germination
F0U64_RS23470	COG0678	peroxiredoxin activity
F0U64_RS23480	COG0412	Dienelactone hydrolase
F0U64_RS23490	COG0315	cyclic pyranopterin monophosphate synthase activity
F0U64_RS23500	COG0314	molybdopterin synthase activity
F0U64_RS23505	COG0521	Mo-molybdopterin cofactor biosynthetic process
F0U64_RS23510	COG0303	'Molybdopterin
F0U64_RS23520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F0U64_RS23540	COG3383	formate dehydrogenase (NAD+) activity
F0U64_RS23545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F0U64_RS23555	COG2223	nitrite transmembrane transporter activity
F0U64_RS23580	COG0583	DNA-binding transcription factor activity
F0U64_RS23585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F0U64_RS23620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0U64_RS23635	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS23655	COG2828	Protein conserved in bacteria
F0U64_RS23660	COG0583	DNA-binding transcription factor activity
F0U64_RS23665	COG0456	acetyltransferase
F0U64_RS23705	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS23730	COG4774	siderophore transport
F0U64_RS23750	COG4585	Histidine kinase
F0U64_RS23755	COG0671	phosphoesterase, PA-phosphatase related
F0U64_RS23770	COG1666	GTP binding
F0U64_RS23775	COG1120	ATPase activity
F0U64_RS23780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_RS23785	COG4558	Periplasmic binding protein
F0U64_RS23790	COG3720	iron ion transport
F0U64_RS23800	COG3712	iron ion homeostasis
F0U64_RS23805	COG1595	DNA-templated transcription, initiation
F0U64_RS23820	COG2378	regulation of single-species biofilm formation
F0U64_RS23850	COG1113	amino acid transport
F0U64_RS23860	COG1522	sequence-specific DNA binding
F0U64_RS23870	COG3191	aminopeptidase activity
F0U64_RS23875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS23880	COG0765	amino acid transport
F0U64_RS23885	COG1126	abc transporter atp-binding protein
F0U64_RS23890	COG4942	peptidase
F0U64_RS23910	COG1999	signal sequence binding
F0U64_RS23925	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
F0U64_RS23935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0U64_RS23940	COG1845	cytochrome c oxidase, subunit III
F0U64_RS23945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F0U64_RS23955	COG4772	TonB-dependent receptor
F0U64_RS23975	COG0280	phosphate acetyltransferase
F0U64_RS23975	COG0281	malic enzyme
F0U64_RS23990	COG0697	spore germination
F0U64_RS24025	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS24030	COG0583	DNA-binding transcription factor activity
F0U64_RS24050	COG1396	sequence-specific DNA binding
F0U64_RS24055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0U64_RS24080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0U64_RS24095	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
F0U64_RS24100	COG1285	pathogenesis
F0U64_RS24105	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS24110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0U64_RS24125	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F0U64_RS24140	COG3712	iron ion homeostasis
F0U64_RS24145	COG1595	DNA-templated transcription, initiation
F0U64_RS24160	COG4773	Receptor
F0U64_RS24185	COG0330	HflC and HflK could
F0U64_RS24210	COG2807	transmembrane transport
F0U64_RS24215	COG2207	Transcriptional regulator
F0U64_RS24220	COG4106	trans-aconitate 2-methyltransferase activity
F0U64_RS24235	COG0583	DNA-binding transcription factor activity
F0U64_RS24275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F0U64_RS24280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS24285	COG0477	Major facilitator Superfamily
F0U64_RS24290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F0U64_RS24295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0U64_RS24300	COG1845	cytochrome c oxidase, subunit III
F0U64_RS24305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F0U64_RS24315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS24320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS24325	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS24335	COG2814	Major facilitator Superfamily
F0U64_RS24350	COG0625	glutathione transferase activity
F0U64_RS24400	COG3707	response regulator
F0U64_RS24405	COG2146	nitrite reductase [NAD(P)H] activity
F0U64_RS24405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0U64_RS24410	COG2146	nitrite reductase [NAD(P)H] activity
F0U64_RS24410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0U64_RS24415	COG0243	molybdopterin cofactor binding
F0U64_RS24425	COG0667	Aldo Keto reductase
F0U64_RS24445	COG0583	DNA-binding transcription factor activity
F0U64_RS24450	COG0023	Translation Initiation Factor
F0U64_RS24460	COG0456	acetyltransferase
F0U64_RS24460	COG0454	-acetyltransferase
F0U64_RS24465	COG0583	DNA-binding transcription factor activity
F0U64_RS24470	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_RS24485	COG0840	transmembrane signaling receptor activity
F0U64_RS24490	COG2199	diguanylate cyclase activity
F0U64_RS24490	COG2203	Gaf domain
F0U64_RS24495	COG0640	Transcriptional regulator
F0U64_RS24505	COG0740	serine-type endopeptidase activity
F0U64_RS24510	COG2814	Major facilitator Superfamily
F0U64_RS24540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_RS24550	COG0596	Alpha beta hydrolase
F0U64_RS24560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0U64_RS24570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_RS24575	COG0583	DNA-binding transcription factor activity
F0U64_RS24610	COG0028	Belongs to the TPP enzyme family
F0U64_RS24630	COG1230	cation diffusion facilitator family transporter
F0U64_RS24650	COG1132	(ABC) transporter
F0U64_RS24660	COG1201	RNA secondary structure unwinding
F0U64_RS24665	COG1793	dna ligase
F0U64_RS24670	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F0U64_RS24670	COG1793	dna ligase
F0U64_RS24705	COG1960	acyl-CoA dehydrogenase activity
F0U64_RS24715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS24720	COG0697	spore germination
F0U64_RS24730	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS24740	COG0436	Aminotransferase
F0U64_RS24745	COG0583	DNA-binding transcription factor activity
F0U64_RS24750	COG0583	DNA-binding transcription factor activity
F0U64_RS24775	COG0583	DNA-binding transcription factor activity
F0U64_RS24780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_RS24785	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS24790	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_RS24805	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS24850	COG1595	DNA-templated transcription, initiation
F0U64_RS24880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F0U64_RS24885	COG0459	protein refolding
F0U64_RS24895	COG1846	Transcriptional regulator
F0U64_RS24915	COG1917	Cupin 2, conserved barrel domain protein
F0U64_RS24940	COG1137	ATPase activity
F0U64_RS24950	COG0246	Mannitol dehydrogenase
F0U64_RS24955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F0U64_RS24960	COG1252	NADH dehydrogenase
F0U64_RS24965	COG0284	orotidine-5'-phosphate decarboxylase activity
F0U64_RS24970	COG1546	Belongs to the CinA family
F0U64_RS24985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0U64_RS24990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F0U64_RS25015	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F0U64_RS25020	COG3639	organic phosphonate transmembrane transporter activity
F0U64_RS25025	COG3639	organic phosphonate transmembrane transporter activity
F0U64_RS25045	COG0742	ribosomal rna small subunit methyltransferase
F0U64_RS25050	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F0U64_RS25055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F0U64_RS25060	COG3135	benzoate transporter
F0U64_RS25075	COG2814	Major facilitator Superfamily
F0U64_RS25090	COG0488	(ABC) transporter
F0U64_RS25095	COG4773	Receptor
F0U64_RS25100	COG4804	nuclease activity
F0U64_RS25125	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F0U64_RS25135	COG0732	type I restriction modification DNA specificity domain
F0U64_RS25140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F0U64_RS25155	COG0582	viral genome integration into host DNA
F0U64_RS25160	COG0012	GTP binding
F0U64_RS25170	COG0193	aminoacyl-tRNA hydrolase activity
F0U64_RS25190	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F0U64_RS25195	COG0840	transmembrane signaling receptor activity
F0U64_RS25210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F0U64_RS25235	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
F0U64_RS25245	COG0204	Acyl-transferase
F0U64_RS25250	COG1368	sulfuric ester hydrolase activity
F0U64_RS25255	COG2186	Transcriptional regulator
F0U64_RS25260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_RS25270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_RS25280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F0U64_RS25280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_RS25290	COG2205	protein histidine kinase activity
F0U64_RS25295	COG0745	RESPONSE REGULATOR receiver
F0U64_RS25300	COG0277	FAD linked oxidase domain protein
F0U64_RS25315	COG0166	Belongs to the GPI family
F0U64_RS25320	COG0405	Gamma-glutamyltransferase
F0U64_RS25325	COG0438	transferase activity, transferring glycosyl groups
F0U64_RS25335	COG0438	transferase activity, transferring glycosyl groups
F0U64_RS25360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F0U64_RS25365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0U64_RS25395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS25400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0U64_RS25415	COG0747	negative chemotaxis
F0U64_RS25420	COG0601	transmembrane transport
F0U64_RS25425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS25430	COG4172	Belongs to the ABC transporter superfamily
F0U64_RS25435	COG0154	amidase activity
F0U64_RS25450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0U64_RS25450	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0U64_RS25455	COG0509	glycine decarboxylation via glycine cleavage system
F0U64_RS25460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F0U64_RS25475	COG2081	HI0933 family
F0U64_RS25495	COG3706	GGDEF domain
F0U64_RS25505	COG0717	Belongs to the dCTP deaminase family
F0U64_RS25520	COG0489	protein tyrosine kinase activity
F0U64_RS25530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0U64_RS25530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0U64_RS25535	COG1054	Belongs to the UPF0176 family
F0U64_RS25550	COG2755	lipolytic protein G-D-S-L family
F0U64_RS25550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F0U64_RS25565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0U64_RS25585	COG2200	EAL domain
F0U64_RS25605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_RS25610	COG0842	Transport permease protein
F0U64_RS25610	COG1129	ABC transporter
F0U64_RS25615	COG0842	Transport permease protein
F0U64_RS25625	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS25630	COG0583	DNA-binding transcription factor activity
F0U64_RS25635	COG0697	spore germination
F0U64_RS25640	COG1271	oxidase subunit
F0U64_RS25645	COG1294	oxidase, subunit
F0U64_RS25655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS25690	COG3258	Cytochrome c
F0U64_RS25700	COG0625	glutathione transferase activity
F0U64_RS25705	COG2986	histidine ammonia-lyase
F0U64_RS25710	COG1234	tRNA 3'-trailer cleavage
F0U64_RS25720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F0U64_RS25735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F0U64_RS25765	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0U64_RS25785	COG1595	DNA-templated transcription, initiation
F0U64_RS25790	COG3712	iron ion homeostasis
F0U64_RS25800	COG0165	Argininosuccinate lyase
F0U64_RS25805	COG2205	protein histidine kinase activity
F0U64_RS25810	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F0U64_RS25825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_RS25855	COG0477	Major facilitator Superfamily
F0U64_RS25865	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS25870	COG3246	L-lysine catabolic process to acetate
F0U64_RS25885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F0U64_RS25890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_RS25895	COG0154	amidase activity
F0U64_RS25900	COG0372	Belongs to the citrate synthase family
F0U64_RS25905	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_RS25950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0U64_RS25955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_RS25960	COG0583	DNA-binding transcription factor activity
F0U64_RS25965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F0U64_RS25985	COG1652	LysM domain
F0U64_RS25990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F0U64_RS25995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0U64_RS26010	COG0625	glutathione transferase activity
F0U64_RS26035	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_RS26070	COG3550	peptidyl-serine autophosphorylation
F0U64_RS26090	COG1414	Transcriptional regulator
F0U64_RS26100	COG0800	Aldolase
F0U64_RS26105	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_RS26110	COG2271	Major facilitator Superfamily
F0U64_RS26115	COG1131	(ABC) transporter
F0U64_RS26130	COG4774	siderophore transport
F0U64_RS26135	COG2814	Major facilitator Superfamily
F0U64_RS26140	COG0326	Molecular chaperone. Has ATPase activity
F0U64_RS26150	COG2233	PERMEase
F0U64_RS26180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS26185	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0U64_RS26190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0U64_RS26260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS26265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_RS26270	COG3246	L-lysine catabolic process to acetate
F0U64_RS26280	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS26390	COG0784	Response regulator, receiver
F0U64_RS26390	COG5002	protein histidine kinase activity
F0U64_RS26390	COG2198	Histidine kinase
F0U64_RS26410	COG0583	DNA-binding transcription factor activity
F0U64_RS26420	COG1695	Transcriptional regulator
F0U64_RS26435	COG0477	Major facilitator Superfamily
F0U64_RS26450	COG0277	FAD linked oxidase domain protein
F0U64_RS26460	COG3842	ATPase activity
F0U64_RS26465	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_RS26485	COG0628	permease
F0U64_RS26490	COG0583	DNA-binding transcription factor activity
F0U64_RS26495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_RS26515	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
F0U64_RS26525	COG2186	Transcriptional regulator
F0U64_RS26535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0U64_RS26560	COG0410	ABC transporter
F0U64_RS26565	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS26570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F0U64_RS26580	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0U64_RS26585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0U64_RS26590	COG0583	DNA-binding transcription factor activity
F0U64_RS26595	COG0129	dihydroxy-acid dehydratase activity
F0U64_RS26605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0U64_RS26610	COG0583	DNA-binding transcription factor activity
F0U64_RS26625	COG2200	EAL domain
F0U64_RS26630	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F0U64_RS26635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
F0U64_RS26640	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_RS26645	COG2031	fatty acid transporter
F0U64_RS26650	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS26655	COG1414	Transcriptional regulator
F0U64_RS26665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0U64_RS26670	COG4829	muconolactone delta-isomerase
F0U64_RS26680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_RS26700	COG0288	reversible hydration of carbon dioxide
F0U64_RS26705	COG1802	Transcriptional regulator
F0U64_RS26710	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS26720	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_RS26740	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS26745	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS26750	COG1053	succinate dehydrogenase
F0U64_RS26755	COG0625	glutathione transferase activity
F0U64_RS26775	COG0583	DNA-binding transcription factor activity
F0U64_RS26785	COG0583	DNA-binding transcription factor activity
F0U64_RS26790	COG0477	Major facilitator Superfamily
F0U64_RS26815	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_RS26835	COG1464	Belongs to the NlpA lipoprotein family
F0U64_RS26850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F0U64_RS26855	COG2890	protein-(glutamine-N5) methyltransferase activity
F0U64_RS26860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F0U64_RS26875	COG1280	lysine exporter protein (LysE YggA)
F0U64_RS26880	COG1522	sequence-specific DNA binding
F0U64_RS26900	COG3622	Belongs to the hyi family
F0U64_RS26920	COG0583	DNA-binding transcription factor activity
F0U64_RS26925	COG2186	Transcriptional regulator
F0U64_RS26930	COG3395	kinase activity
F0U64_RS26935	COG2084	Dehydrogenase
F0U64_RS26940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_RS26945	COG3622	Belongs to the hyi family
F0U64_RS26950	COG0235	Class ii aldolase
F0U64_RS27020	COG0142	geranyltranstransferase activity
F0U64_RS27025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F0U64_RS27030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F0U64_RS27035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F0U64_RS27040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F0U64_RS27055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0U64_RS27060	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F0U64_RS27070	COG2186	Transcriptional regulator
F0U64_RS27075	COG3447	MASE1 domain protein
F0U64_RS27075	COG5001	Diguanylate cyclase
F0U64_RS27075	COG5002	protein histidine kinase activity
F0U64_RS27080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0U64_RS27085	COG0793	Belongs to the peptidase S41A family
F0U64_RS27090	COG4942	peptidase
F0U64_RS27095	COG0588	phosphoglycerate mutase activity
F0U64_RS27100	COG1054	Belongs to the UPF0176 family
F0U64_RS27105	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F0U64_RS27110	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F0U64_RS27115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F0U64_RS27120	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS27130	COG1040	competence protein
F0U64_RS27135	COG2226	methyltransferase
F0U64_RS27140	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
F0U64_RS27145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F0U64_RS27150	COG0569	domain protein
F0U64_RS27155	COG2204	response regulator
F0U64_RS27160	COG5000	phosphorelay sensor kinase activity
F0U64_RS27170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0U64_RS27170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F0U64_RS27175	COG1280	lysine exporter protein (LysE YggA)
F0U64_RS27180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0U64_RS27190	COG1733	regulation of RNA biosynthetic process
F0U64_RS27210	COG0546	phosphoglycolate phosphatase activity
F0U64_RS27220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F0U64_RS27225	COG0242	peptide deformylase activity
F0U64_RS27230	COG0758	DNA mediated transformation
F0U64_RS27245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_RS27250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS27255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F0U64_RS27260	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS27275	COG1238	metal cluster binding
F0U64_RS27280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0U64_RS27285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_RS27300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F0U64_RS27305	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F0U64_RS27310	COG4988	ABC transporter
F0U64_RS27320	COG1294	oxidase, subunit
F0U64_RS27335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
F0U64_RS27345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F0U64_RS27360	COG1137	ATPase activity
F0U64_RS27365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F0U64_RS27375	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
F0U64_RS27380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS27395	COG1660	Displays ATPase and GTPase activities
F0U64_RS27405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0U64_RS27415	COG0792	nuclease activity
F0U64_RS27420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F0U64_RS27430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_RS27435	COG1464	Belongs to the NlpA lipoprotein family
F0U64_RS27440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F0U64_RS27450	COG1309	transcriptional regulator
F0U64_RS27455	COG0471	metal ion transport
F0U64_RS27460	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F0U64_RS27465	COG0772	Belongs to the SEDS family
F0U64_RS27470	COG0768	penicillin binding
F0U64_RS27480	COG1792	Involved in formation and maintenance of cell shape
F0U64_RS27485	COG1077	Cell shape determining protein MreB Mrl
F0U64_RS27490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F0U64_RS27495	COG0154	amidase activity
F0U64_RS27500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F0U64_RS27515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F0U64_RS27520	COG0708	Exodeoxyribonuclease III
F0U64_RS27525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0U64_RS27535	COG0583	DNA-binding transcription factor activity
F0U64_RS27545	COG0583	DNA-binding transcription factor activity
F0U64_RS27570	COG1764	response to oxidative stress
F0U64_RS27575	COG1846	Transcriptional regulator
F0U64_RS27635	COG0640	Transcriptional regulator
F0U64_RS27665	COG3189	MarR family transcriptional regulator
F0U64_RS27685	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_RS27690	COG0351	phosphomethylpyrimidine kinase
F0U64_RS27690	COG0352	thiamine-phosphate diphosphorylase activity
F0U64_RS27690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F0U64_RS27750	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F0U64_RS27755	COG0513	Belongs to the DEAD box helicase family
F0U64_RS27765	COG0617	tRNA 3'-terminal CCA addition
F0U64_RS27775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F0U64_RS27785	COG2308	Evidence 4 Homologs of previously reported genes of
F0U64_RS27795	COG1305	Transglutaminase-like
F0U64_RS27815	COG1950	PFAM Membrane protein of
F0U64_RS27820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F0U64_RS27825	COG0438	transferase activity, transferring glycosyl groups
F0U64_RS27840	COG0066	3-isopropylmalate dehydratase activity
F0U64_RS27850	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_RS27855	COG0583	DNA-binding transcription factor activity
F0U64_RS27860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F0U64_RS27895	COG0477	Major facilitator Superfamily
F0U64_RS27900	COG0154	amidase activity
F0U64_RS27905	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F0U64_RS27920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F0U64_RS27930	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F0U64_RS27935	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F0U64_RS27945	COG0803	Belongs to the bacterial solute-binding protein 9 family
F0U64_RS27960	COG0735	belongs to the Fur family
F0U64_RS27965	COG0523	cobalamin synthesis protein
F0U64_RS27975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F0U64_RS27980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F0U64_RS27990	COG2096	Adenosyltransferase
F0U64_RS28000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F0U64_RS28015	COG0321	lipoyl(octanoyl) transferase activity
F0U64_RS28020	COG2921	Belongs to the UPF0250 family
F0U64_RS28030	COG1686	Belongs to the peptidase S11 family
F0U64_RS28055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0U64_RS28065	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
F0U64_RS28075	COG0859	PFAM glycosyl transferase family 9
F0U64_RS28100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0U64_RS28135	COG0367	asparagine synthase
F0U64_RS28150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_RS28160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0U64_RS28170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0U64_RS28185	COG0175	sulfate reduction
F0U64_RS28215	COG2226	methyltransferase
F0U64_RS28230	COG0367	asparagine synthase
F0U64_RS28245	COG2814	Major facilitator Superfamily
F0U64_RS28275	COG3568	Endonuclease Exonuclease Phosphatase
F0U64_RS28280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F0U64_RS28305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0U64_RS28320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_RS28325	COG1956	GAF domain-containing protein
F0U64_RS28330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_RS28355	COG2186	Transcriptional regulator
F0U64_RS28395	COG4106	trans-aconitate 2-methyltransferase activity
F0U64_RS28405	COG2814	Major facilitator Superfamily
F0U64_RS28415	COG0625	glutathione transferase activity
F0U64_RS28420	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F0U64_RS28425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F0U64_RS28430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0U64_RS28440	COG1965	Belongs to the frataxin family
F0U64_RS28450	COG0019	diaminopimelate decarboxylase activity
F0U64_RS28455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0U64_RS28460	COG1333	cytochrome c biogenesis protein
F0U64_RS28470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F0U64_RS28485	COG4232	protein-disulfide reductase activity
F0U64_RS28490	COG1324	tolerance protein
F0U64_RS28500	COG0203	ribosomal protein L17
F0U64_RS28505	COG0202	RNA polymerase activity
F0U64_RS28510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F0U64_RS28515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F0U64_RS28520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F0U64_RS28525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0U64_RS28530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F0U64_RS28535	COG0201	protein transport
F0U64_RS28540	COG0200	Binds to the 23S rRNA
F0U64_RS28545	COG1841	ribosomal large subunit assembly
F0U64_RS28550	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F0U64_RS28555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F0U64_RS28560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F0U64_RS28565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F0U64_RS28570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F0U64_RS28575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F0U64_RS28580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F0U64_RS28585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F0U64_RS28600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0U64_RS28600	COG2169	Transcriptional regulator
F0U64_RS28615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_RS28625	COG0411	ABC transporter
F0U64_RS28650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F0U64_RS28655	COG0255	Belongs to the universal ribosomal protein uL29 family
F0U64_RS28660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F0U64_RS28665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F0U64_RS28670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F0U64_RS28675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F0U64_RS28680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F0U64_RS28685	COG0089	rRNA binding
F0U64_RS28695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F0U64_RS28700	COG0051	transcription antitermination factor activity, RNA binding
F0U64_RS28705	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0U64_RS28710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F0U64_RS28715	COG0049	tRNA binding
F0U64_RS28720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F0U64_RS28725	COG0745	RESPONSE REGULATOR receiver
F0U64_RS28740	COG5002	protein histidine kinase activity
F0U64_RS28755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F0U64_RS28760	COG0085	RNA polymerase activity
F0U64_RS28765	COG0222	ribosome binding
F0U64_RS28770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F0U64_RS28775	COG0081	regulation of translation
F0U64_RS28780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F0U64_RS28790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F0U64_RS28800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0U64_RS28840	COG1840	ABC-type Fe3 transport system, periplasmic component
F0U64_RS28845	COG3842	ATPase activity
F0U64_RS28855	COG1349	DNA-binding transcription factor activity
F0U64_RS28880	COG0583	DNA-binding transcription factor activity
F0U64_RS28885	COG0252	asparaginase activity
F0U64_RS28890	COG1475	DNA binding
F0U64_RS28900	COG1192	Involved in chromosome partitioning
F0U64_RS28905	COG0357	Ribosomal RNA small subunit methyltransferase G
F0U64_RS28910	COG0445	tRNA wobble uridine modification
F0U64_RS28915	COG1278	Cold shock
F0U64_RS28920	COG3180	Ammonia monooxygenase
F0U64_RS28925	COG0436	Aminotransferase
F0U64_RS28960	COG0038	chloride channel
F0U64_RS28975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F0U64_RS28985	COG0601	transmembrane transport
F0U64_RS28990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_RS28995	COG0444	Belongs to the ABC transporter superfamily
F0U64_RS29000	COG4608	Belongs to the ABC transporter superfamily
F0U64_RS29005	COG1473	amidohydrolase
F0U64_RS29010	COG2175	clavaminate synthase activity
F0U64_RS29025	COG0753	catalase activity
F0U64_RS29035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F0U64_RS29040	COG0594	ribonuclease P activity
F0U64_RS29045	COG0230	Belongs to the bacterial ribosomal protein bL34 family