locus-tag	class	description
GCD73_RS00010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GCD73_RS00015	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GCD73_RS00020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GCD73_RS00040	COG1301	dicarboxylic acid transport
GCD73_RS00055	COG0583	DNA-binding transcription factor activity
GCD73_RS00060	COG0405	Gamma-glutamyltransferase
GCD73_RS00085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GCD73_RS00095	COG0739	heme binding
GCD73_RS00105	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCD73_RS00115	COG0306	phosphate transporter
GCD73_RS00155	COG0625	glutathione transferase activity
GCD73_RS00170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GCD73_RS00175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GCD73_RS00185	COG0126	phosphoglycerate kinase activity
GCD73_RS00190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GCD73_RS00195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GCD73_RS00200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GCD73_RS00205	COG2732	(Barnase) inhibitor
GCD73_RS00215	COG0280	phosphate acetyltransferase
GCD73_RS00215	COG0281	malic enzyme
GCD73_RS00225	COG0436	Aminotransferase
GCD73_RS00230	COG0741	lytic transglycosylase activity
GCD73_RS00235	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GCD73_RS00250	COG4575	ribosome binding
GCD73_RS00260	COG0243	molybdopterin cofactor binding
GCD73_RS00265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCD73_RS00270	COG1116	anion transmembrane transporter activity
GCD73_RS00275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCD73_RS00280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCD73_RS00290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GCD73_RS00290	COG1648	precorrin-2 dehydrogenase activity
GCD73_RS00295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GCD73_RS00300	COG2027	D-alanyl-D-alanine carboxypeptidase
GCD73_RS00305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GCD73_RS00310	COG0343	queuine tRNA-ribosyltransferase activity
GCD73_RS00315	COG1862	Preprotein translocase
GCD73_RS00320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCD73_RS00325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCD73_RS00350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GCD73_RS00355	COG1702	phosphate starvation-inducible protein PhoH
GCD73_RS00360	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GCD73_RS00365	COG4535	Mg2 and Co2 transporter CorC
GCD73_RS00370	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GCD73_RS00375	COG0667	Aldo Keto reductase
GCD73_RS00410	COG1366	Belongs to the anti-sigma-factor antagonist family
GCD73_RS00410	COG2202	Pas domain
GCD73_RS00415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GCD73_RS00420	COG0697	spore germination
GCD73_RS00430	COG0678	peroxiredoxin activity
GCD73_RS00440	COG0412	Dienelactone hydrolase
GCD73_RS00450	COG0315	cyclic pyranopterin monophosphate synthase activity
GCD73_RS00460	COG0314	molybdopterin synthase activity
GCD73_RS00465	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCD73_RS00470	COG0303	'Molybdopterin
GCD73_RS00475	COG0746	molybdenum cofactor guanylyltransferase activity
GCD73_RS00480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GCD73_RS00500	COG3383	formate dehydrogenase (NAD+) activity
GCD73_RS00505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GCD73_RS00515	COG2223	nitrite transmembrane transporter activity
GCD73_RS00525	COG1595	DNA-templated transcription, initiation
GCD73_RS00530	COG3712	iron ion homeostasis
GCD73_RS00555	COG4221	oxidoreductase activity
GCD73_RS00580	COG0583	DNA-binding transcription factor activity
GCD73_RS00585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GCD73_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS00620	COG0456	acetyltransferase
GCD73_RS00685	COG0671	phosphoesterase, PA-phosphatase related
GCD73_RS00710	COG0583	DNA-binding transcription factor activity
GCD73_RS00715	COG1666	GTP binding
GCD73_RS00720	COG1120	ATPase activity
GCD73_RS00725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCD73_RS00730	COG4558	Periplasmic binding protein
GCD73_RS00735	COG3720	iron ion transport
GCD73_RS00745	COG3712	iron ion homeostasis
GCD73_RS00750	COG1595	DNA-templated transcription, initiation
GCD73_RS00765	COG2378	regulation of single-species biofilm formation
GCD73_RS00775	COG1113	amino acid transport
GCD73_RS00785	COG1522	sequence-specific DNA binding
GCD73_RS00790	COG1272	protein, Hemolysin III
GCD73_RS00795	COG3191	aminopeptidase activity
GCD73_RS00800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS00805	COG0765	amino acid transport
GCD73_RS00810	COG1126	abc transporter atp-binding protein
GCD73_RS00825	COG1999	signal sequence binding
GCD73_RS00840	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GCD73_RS00850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCD73_RS00855	COG1845	cytochrome c oxidase, subunit III
GCD73_RS00905	COG4772	TonB-dependent receptor
GCD73_RS00935	COG4772	TonB-dependent receptor
GCD73_RS00955	COG0281	malic enzyme
GCD73_RS00955	COG0280	phosphate acetyltransferase
GCD73_RS00985	COG0697	spore germination
GCD73_RS01000	COG0583	DNA-binding transcription factor activity
GCD73_RS01035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCD73_RS01045	COG3145	DNA-N1-methyladenine dioxygenase activity
GCD73_RS01050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GCD73_RS01065	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GCD73_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS01075	COG1285	pathogenesis
GCD73_RS01080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCD73_RS01095	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GCD73_RS01105	COG2706	6-phosphogluconolactonase activity
GCD73_RS01115	COG3712	iron ion homeostasis
GCD73_RS01125	COG0784	Response regulator, receiver
GCD73_RS01125	COG4191	Histidine kinase
GCD73_RS01140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCD73_RS01145	COG0330	HflC and HflK could
GCD73_RS01165	COG2807	transmembrane transport
GCD73_RS01170	COG2207	Transcriptional regulator
GCD73_RS01175	COG4106	trans-aconitate 2-methyltransferase activity
GCD73_RS01180	COG0861	Integral membrane protein TerC family
GCD73_RS01185	COG0583	DNA-binding transcription factor activity
GCD73_RS01215	COG0477	Major facilitator Superfamily
GCD73_RS01220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GCD73_RS01225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCD73_RS01230	COG1845	cytochrome c oxidase, subunit III
GCD73_RS01235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GCD73_RS01250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GCD73_RS01260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCD73_RS01290	COG0519	Catalyzes the synthesis of GMP from XMP
GCD73_RS01315	COG0667	Aldo Keto reductase
GCD73_RS01395	COG1222	aaa ATPase
GCD73_RS01450	COG2133	pyrroloquinoline quinone binding
GCD73_RS01450	COG5183	chlorophyll binding
GCD73_RS01465	COG5295	Hep Hag repeat protein
GCD73_RS01465	COG5295	Hep Hag repeat protein
GCD73_RS01470	COG2814	Major facilitator Superfamily
GCD73_RS01495	COG1116	anion transmembrane transporter activity
GCD73_RS01520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GCD73_RS01525	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GCD73_RS01530	COG2080	2 iron, 2 sulfur cluster binding
GCD73_RS01540	COG2205	protein histidine kinase activity
GCD73_RS01540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS01550	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GCD73_RS01555	COG3850	Histidine kinase
GCD73_RS01555	COG4999	Histidine kinase
GCD73_RS01555	COG3437	response regulator, receiver
GCD73_RS01555	COG2205	protein histidine kinase activity
GCD73_RS01560	COG2204	response regulator
GCD73_RS01590	COG1609	Transcriptional regulator
GCD73_RS01610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCD73_RS01615	COG5001	Diguanylate cyclase
GCD73_RS01615	COG4251	negative regulation of phosphorylation
GCD73_RS01615	COG3706	GGDEF domain
GCD73_RS01615	COG2203	Gaf domain
GCD73_RS01620	COG0840	transmembrane signaling receptor activity
GCD73_RS01630	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS01720	COG1053	succinate dehydrogenase
GCD73_RS01760	COG0583	DNA-binding transcription factor activity
GCD73_RS01765	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS01785	COG4221	oxidoreductase activity
GCD73_RS01810	COG0642	Histidine kinase
GCD73_RS01835	COG3040	lipid binding
GCD73_RS01840	COG3046	protein related to deoxyribodipyrimidine photolyase
GCD73_RS01850	COG3038	cytochrome b561
GCD73_RS01895	COG1454	alcohol dehydrogenase
GCD73_RS01910	COG3135	benzoate transporter
GCD73_RS02095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCD73_RS02115	COG0657	acetylesterase activity
GCD73_RS02140	COG2814	Major facilitator Superfamily
GCD73_RS02145	COG0047	phosphoribosylformylglycinamidine synthase activity
GCD73_RS02180	COG0165	Argininosuccinate lyase
GCD73_RS02230	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS02240	COG0604	alcohol dehydrogenase
GCD73_RS02260	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS02275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GCD73_RS02280	COG0459	protein refolding
GCD73_RS02295	COG0246	Mannitol dehydrogenase
GCD73_RS02300	COG2721	sulfolactate sulfo-lyase activity
GCD73_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS02315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GCD73_RS02325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCD73_RS02330	COG2186	Transcriptional regulator
GCD73_RS02335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GCD73_RS02340	COG1252	NADH dehydrogenase
GCD73_RS02345	COG0284	orotidine-5'-phosphate decarboxylase activity
GCD73_RS02350	COG1546	Belongs to the CinA family
GCD73_RS02355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GCD73_RS02365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GCD73_RS02370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GCD73_RS02395	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GCD73_RS02400	COG3639	organic phosphonate transmembrane transporter activity
GCD73_RS02405	COG3639	organic phosphonate transmembrane transporter activity
GCD73_RS02420	COG0742	ribosomal rna small subunit methyltransferase
GCD73_RS02425	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GCD73_RS02430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCD73_RS02435	COG3135	benzoate transporter
GCD73_RS02450	COG2814	Major facilitator Superfamily
GCD73_RS02475	COG4604	ABC transporter, ATP-binding protein
GCD73_RS02490	COG0012	GTP binding
GCD73_RS02500	COG0193	aminoacyl-tRNA hydrolase activity
GCD73_RS02520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GCD73_RS02525	COG0840	transmembrane signaling receptor activity
GCD73_RS02540	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GCD73_RS02550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCD73_RS02575	COG0204	Acyl-transferase
GCD73_RS02580	COG1368	sulfuric ester hydrolase activity
GCD73_RS02585	COG2186	Transcriptional regulator
GCD73_RS02590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCD73_RS02600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCD73_RS02610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GCD73_RS02610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GCD73_RS02625	COG0745	RESPONSE REGULATOR receiver
GCD73_RS02630	COG0277	FAD linked oxidase domain protein
GCD73_RS02640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GCD73_RS02645	COG0166	Belongs to the GPI family
GCD73_RS02650	COG0438	transferase activity, transferring glycosyl groups
GCD73_RS02655	COG0438	transferase activity, transferring glycosyl groups
GCD73_RS02660	COG0438	transferase activity, transferring glycosyl groups
GCD73_RS02685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GCD73_RS02690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCD73_RS02695	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GCD73_RS02720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCD73_RS02725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GCD73_RS02740	COG0747	negative chemotaxis
GCD73_RS02745	COG0601	transmembrane transport
GCD73_RS02750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS02755	COG4172	Belongs to the ABC transporter superfamily
GCD73_RS02760	COG0154	amidase activity
GCD73_RS02775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GCD73_RS02775	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GCD73_RS02780	COG0509	glycine decarboxylation via glycine cleavage system
GCD73_RS02785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GCD73_RS02800	COG2081	HI0933 family
GCD73_RS02815	COG0456	acetyltransferase
GCD73_RS02815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCD73_RS02820	COG3706	GGDEF domain
GCD73_RS02830	COG0717	Belongs to the dCTP deaminase family
GCD73_RS02845	COG0489	protein tyrosine kinase activity
GCD73_RS02855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCD73_RS02855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCD73_RS02860	COG1054	Belongs to the UPF0176 family
GCD73_RS02890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCD73_RS02895	COG2200	EAL domain
GCD73_RS02910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCD73_RS02915	COG0842	Transport permease protein
GCD73_RS02915	COG1129	ABC transporter
GCD73_RS02920	COG0842	Transport permease protein
GCD73_RS02935	COG1271	oxidase subunit
GCD73_RS02940	COG1294	oxidase, subunit
GCD73_RS02950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCD73_RS02970	COG1053	succinate dehydrogenase
GCD73_RS02970	COG3976	FMN-binding domain protein
GCD73_RS02970	COG0431	NADPH-dependent FMN reductase
GCD73_RS02975	COG0583	DNA-binding transcription factor activity
GCD73_RS02980	COG0625	glutathione transferase activity
GCD73_RS03005	COG1024	Enoyl-CoA hydratase
GCD73_RS03015	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS03020	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS03025	COG0583	DNA-binding transcription factor activity
GCD73_RS03030	COG3618	amidohydrolase
GCD73_RS03045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCD73_RS03060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCD73_RS03110	COG0411	ABC transporter
GCD73_RS03120	COG0559	Belongs to the binding-protein-dependent transport system permease family
GCD73_RS03140	COG1131	(ABC) transporter
GCD73_RS03145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCD73_RS03155	COG0583	DNA-binding transcription factor activity
GCD73_RS03170	COG2267	carboxylic ester hydrolase activity
GCD73_RS03175	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS03195	COG0840	transmembrane signaling receptor activity
GCD73_RS03210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GCD73_RS03220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS03230	COG2814	Major facilitator Superfamily
GCD73_RS03240	COG0165	Argininosuccinate lyase
GCD73_RS03250	COG5002	protein histidine kinase activity
GCD73_RS03295	COG3712	iron ion homeostasis
GCD73_RS03305	COG3246	L-lysine catabolic process to acetate
GCD73_RS03320	COG0154	amidase activity
GCD73_RS03325	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS03330	COG0583	DNA-binding transcription factor activity
GCD73_RS03335	COG1132	(ABC) transporter
GCD73_RS03350	COG0583	DNA-binding transcription factor activity
GCD73_RS03370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCD73_RS03375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS03380	COG0583	DNA-binding transcription factor activity
GCD73_RS03385	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GCD73_RS03400	COG1652	LysM domain
GCD73_RS03405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GCD73_RS03410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCD73_RS03425	COG0625	glutathione transferase activity
GCD73_RS03435	COG0277	FAD linked oxidase domain protein
GCD73_RS03440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCD73_RS03460	COG1012	belongs to the aldehyde dehydrogenase family
GCD73_RS03465	COG0583	DNA-binding transcription factor activity
GCD73_RS03470	COG5002	protein histidine kinase activity
GCD73_RS03490	COG1414	Transcriptional regulator
GCD73_RS03495	COG3734	2-keto-3-deoxy-galactonokinase
GCD73_RS03500	COG0800	Aldolase
GCD73_RS03505	COG4948	Mandelate Racemase Muconate Lactonizing
GCD73_RS03510	COG2271	Major facilitator Superfamily
GCD73_RS03515	COG3657	addiction module killer protein
GCD73_RS03525	COG2814	Major facilitator Superfamily
GCD73_RS03535	COG1396	sequence-specific DNA binding
GCD73_RS03540	COG0326	Molecular chaperone. Has ATPase activity
GCD73_RS03545	COG2233	PERMEase
GCD73_RS03555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCD73_RS03595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCD73_RS03600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCD73_RS03610	COG0583	DNA-binding transcription factor activity
GCD73_RS03630	COG0477	Major facilitator Superfamily
GCD73_RS03640	COG0583	DNA-binding transcription factor activity
GCD73_RS03645	COG0436	Aminotransferase
GCD73_RS03650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCD73_RS03655	COG0583	DNA-binding transcription factor activity
GCD73_RS03665	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GCD73_RS03690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS03710	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS03745	COG4638	Rieske (2fe-2S)
GCD73_RS03755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCD73_RS03760	COG3246	L-lysine catabolic process to acetate
GCD73_RS03770	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS03825	COG0583	DNA-binding transcription factor activity
GCD73_RS03835	COG1695	Transcriptional regulator
GCD73_RS03845	COG0477	Major facilitator Superfamily
GCD73_RS03860	COG0628	permease
GCD73_RS03865	COG0583	DNA-binding transcription factor activity
GCD73_RS03870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCD73_RS03910	COG3829	transcription factor binding
GCD73_RS04010	COG0077	Prephenate dehydratase
GCD73_RS04010	COG1605	Chorismate mutase
GCD73_RS04020	COG2081	HI0933 family
GCD73_RS04025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCD73_RS04045	COG1129	ABC transporter
GCD73_RS04070	COG1126	abc transporter atp-binding protein
GCD73_RS04075	COG0765	amino acid transport
GCD73_RS04080	COG4597	amino acid ABC transporter
GCD73_RS04085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS04090	COG2884	Cell division ATP-binding protein ftsE
GCD73_RS04095	COG2177	Part of the ABC transporter FtsEX involved in
GCD73_RS04105	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GCD73_RS04110	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GCD73_RS04120	COG2186	Transcriptional regulator
GCD73_RS04150	COG0410	ABC transporter
GCD73_RS04155	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS04160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GCD73_RS04170	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCD73_RS04175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCD73_RS04180	COG0583	DNA-binding transcription factor activity
GCD73_RS04185	COG3550	peptidyl-serine autophosphorylation
GCD73_RS04195	COG0129	dihydroxy-acid dehydratase activity
GCD73_RS04220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GCD73_RS04225	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GCD73_RS04230	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCD73_RS04235	COG2031	fatty acid transporter
GCD73_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS04245	COG1414	Transcriptional regulator
GCD73_RS04255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GCD73_RS04260	COG4829	muconolactone delta-isomerase
GCD73_RS04270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GCD73_RS04290	COG0288	reversible hydration of carbon dioxide
GCD73_RS04295	COG0625	glutathione transferase activity
GCD73_RS04300	COG2207	Transcriptional regulator
GCD73_RS04305	COG0300	oxidoreductase activity
GCD73_RS04320	COG0583	DNA-binding transcription factor activity
GCD73_RS04350	COG0318	PFAM AMP-dependent synthetase and ligase
GCD73_RS04365	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS04370	COG4948	Mandelate Racemase Muconate Lactonizing
GCD73_RS04380	COG1464	Belongs to the NlpA lipoprotein family
GCD73_RS04395	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GCD73_RS04400	COG2890	protein-(glutamine-N5) methyltransferase activity
GCD73_RS04405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GCD73_RS04425	COG3171	Protein conserved in bacteria
GCD73_RS04440	COG3264	Mechanosensitive ion channel
GCD73_RS04440	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GCD73_RS04445	COG1522	sequence-specific DNA binding
GCD73_RS04455	COG5006	permease, DMT superfamily
GCD73_RS04465	COG3622	Belongs to the hyi family
GCD73_RS04480	COG0523	cobalamin synthesis protein
GCD73_RS04490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GCD73_RS04500	COG3842	ATPase activity
GCD73_RS04525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GCD73_RS04535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCD73_RS04560	COG3866	Pectate lyase
GCD73_RS04565	COG4783	chaperone-mediated protein folding
GCD73_RS04565	COG1560	Kdo2-lipid A biosynthetic process
GCD73_RS04590	COG0438	transferase activity, transferring glycosyl groups
GCD73_RS04595	COG0457	Tetratricopeptide repeat
GCD73_RS04610	COG0142	geranyltranstransferase activity
GCD73_RS04620	COG1414	Transcriptional regulator
GCD73_RS04625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GCD73_RS04630	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GCD73_RS04635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GCD73_RS04640	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GCD73_RS04655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCD73_RS04660	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GCD73_RS04670	COG2186	Transcriptional regulator
GCD73_RS04685	COG0793	Belongs to the peptidase S41A family
GCD73_RS04690	COG4942	peptidase
GCD73_RS04695	COG0588	phosphoglycerate mutase activity
GCD73_RS04700	COG1054	Belongs to the UPF0176 family
GCD73_RS04705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCD73_RS04710	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GCD73_RS04715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GCD73_RS04725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GCD73_RS04730	COG1040	competence protein
GCD73_RS04735	COG2226	methyltransferase
GCD73_RS04740	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GCD73_RS04750	COG0569	domain protein
GCD73_RS04755	COG2204	response regulator
GCD73_RS04760	COG5000	phosphorelay sensor kinase activity
GCD73_RS04770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GCD73_RS04770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GCD73_RS04775	COG1280	lysine exporter protein (LysE YggA)
GCD73_RS04785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GCD73_RS04805	COG0546	phosphoglycolate phosphatase activity
GCD73_RS04825	COG0242	peptide deformylase activity
GCD73_RS04830	COG0758	DNA mediated transformation
GCD73_RS04845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS04850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCD73_RS04855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GCD73_RS04860	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS04865	COG0071	Belongs to the small heat shock protein (HSP20) family
GCD73_RS04880	COG1238	metal cluster binding
GCD73_RS04885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCD73_RS04890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCD73_RS04910	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GCD73_RS04915	COG4988	ABC transporter
GCD73_RS04925	COG1294	oxidase, subunit
GCD73_RS04930	COG1271	oxidase subunit
GCD73_RS04940	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GCD73_RS04950	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GCD73_RS04965	COG1137	ATPase activity
GCD73_RS04970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCD73_RS04980	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GCD73_RS04985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCD73_RS04990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GCD73_RS04990	COG2010	Cytochrome c
GCD73_RS05000	COG1660	Displays ATPase and GTPase activities
GCD73_RS05010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCD73_RS05025	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GCD73_RS05030	COG2823	Periplasmic or secreted lipoprotein
GCD73_RS05035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCD73_RS05040	COG1464	Belongs to the NlpA lipoprotein family
GCD73_RS05045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GCD73_RS05055	COG1309	transcriptional regulator
GCD73_RS05060	COG0471	metal ion transport
GCD73_RS05065	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GCD73_RS05070	COG0772	Belongs to the SEDS family
GCD73_RS05075	COG0768	penicillin binding
GCD73_RS05085	COG1792	Involved in formation and maintenance of cell shape
GCD73_RS05090	COG1077	Cell shape determining protein MreB Mrl
GCD73_RS05095	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GCD73_RS05100	COG0154	amidase activity
GCD73_RS05105	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GCD73_RS05120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GCD73_RS05125	COG0708	Exodeoxyribonuclease III
GCD73_RS05130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GCD73_RS05140	COG0583	DNA-binding transcription factor activity
GCD73_RS05150	COG0583	DNA-binding transcription factor activity
GCD73_RS05175	COG1764	response to oxidative stress
GCD73_RS05180	COG1846	Transcriptional regulator
GCD73_RS05235	COG0640	Transcriptional regulator
GCD73_RS05260	COG0297	glycogen (starch) synthase activity
GCD73_RS05265	COG3189	MarR family transcriptional regulator
GCD73_RS05270	COG0352	thiamine-phosphate diphosphorylase activity
GCD73_RS05270	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GCD73_RS05270	COG0351	phosphomethylpyrimidine kinase
GCD73_RS05275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GCD73_RS05280	COG0513	Belongs to the DEAD box helicase family
GCD73_RS05290	COG0617	tRNA 3'-terminal CCA addition
GCD73_RS05300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GCD73_RS05305	COG2308	Evidence 4 Homologs of previously reported genes of
GCD73_RS05325	COG1024	Enoyl-CoA hydratase
GCD73_RS05335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS05355	COG0673	inositol 2-dehydrogenase activity
GCD73_RS05360	COG1609	Transcriptional regulator
GCD73_RS05385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GCD73_RS05390	COG1950	PFAM Membrane protein of
GCD73_RS05395	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GCD73_RS05400	COG0438	transferase activity, transferring glycosyl groups
GCD73_RS05415	COG0066	3-isopropylmalate dehydratase activity
GCD73_RS05425	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS05430	COG0583	DNA-binding transcription factor activity
GCD73_RS05435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCD73_RS05470	COG0477	Major facilitator Superfamily
GCD73_RS05475	COG0154	amidase activity
GCD73_RS05480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GCD73_RS05490	COG1560	Kdo2-lipid A biosynthetic process
GCD73_RS05495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GCD73_RS05505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GCD73_RS05510	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GCD73_RS05520	COG0803	Belongs to the bacterial solute-binding protein 9 family
GCD73_RS05540	COG0735	belongs to the Fur family
GCD73_RS05545	COG0523	cobalamin synthesis protein
GCD73_RS05555	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GCD73_RS05560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GCD73_RS05570	COG2096	Adenosyltransferase
GCD73_RS05580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GCD73_RS05585	COG1609	Transcriptional regulator
GCD73_RS05595	COG0321	lipoyl(octanoyl) transferase activity
GCD73_RS05610	COG1686	Belongs to the peptidase S11 family
GCD73_RS05635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GCD73_RS05645	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GCD73_RS05655	COG0859	PFAM glycosyl transferase family 9
GCD73_RS05675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCD73_RS05685	COG1086	Polysaccharide biosynthesis protein
GCD73_RS05710	COG3274	enterobacterial common antigen metabolic process
GCD73_RS05715	COG0438	transferase activity, transferring glycosyl groups
GCD73_RS05720	COG0357	Ribosomal RNA small subunit methyltransferase G
GCD73_RS05740	COG2814	Major facilitator Superfamily
GCD73_RS05745	COG0697	spore germination
GCD73_RS05765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCD73_RS05770	COG3568	Endonuclease Exonuclease Phosphatase
GCD73_RS05775	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GCD73_RS05800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GCD73_RS05815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCD73_RS05820	COG1956	GAF domain-containing protein
GCD73_RS05825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCD73_RS05850	COG2186	Transcriptional regulator
GCD73_RS05855	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GCD73_RS05890	COG4948	Mandelate Racemase Muconate Lactonizing
GCD73_RS05895	COG0583	DNA-binding transcription factor activity
GCD73_RS05925	COG2814	Major facilitator Superfamily
GCD73_RS05935	COG0625	glutathione transferase activity
GCD73_RS05940	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GCD73_RS05945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GCD73_RS05950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GCD73_RS05960	COG1965	Belongs to the frataxin family
GCD73_RS05975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCD73_RS05980	COG1333	cytochrome c biogenesis protein
GCD73_RS05990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GCD73_RS06005	COG4232	protein-disulfide reductase activity
GCD73_RS06010	COG1324	tolerance protein
GCD73_RS06015	COG0537	adenosine 5'-monophosphoramidase activity
GCD73_RS06020	COG0203	ribosomal protein L17
GCD73_RS06025	COG0202	RNA polymerase activity
GCD73_RS06030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GCD73_RS06035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GCD73_RS06040	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GCD73_RS06045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCD73_RS06050	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GCD73_RS06055	COG0201	protein transport
GCD73_RS06060	COG0200	Binds to the 23S rRNA
GCD73_RS06065	COG1841	ribosomal large subunit assembly
GCD73_RS06070	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GCD73_RS06075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GCD73_RS06080	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GCD73_RS06085	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GCD73_RS06090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GCD73_RS06095	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GCD73_RS06100	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GCD73_RS06105	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GCD73_RS06125	COG2207	Transcriptional regulator
GCD73_RS06140	COG0411	ABC transporter
GCD73_RS06165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GCD73_RS06170	COG0255	Belongs to the universal ribosomal protein uL29 family
GCD73_RS06175	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GCD73_RS06180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GCD73_RS06185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GCD73_RS06190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GCD73_RS06195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GCD73_RS06200	COG0089	rRNA binding
GCD73_RS06210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GCD73_RS06215	COG0051	transcription antitermination factor activity, RNA binding
GCD73_RS06220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GCD73_RS06225	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GCD73_RS06230	COG0049	tRNA binding
GCD73_RS06235	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GCD73_RS06240	COG0745	RESPONSE REGULATOR receiver
GCD73_RS06270	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GCD73_RS06275	COG0085	RNA polymerase activity
GCD73_RS06280	COG0222	ribosome binding
GCD73_RS06285	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GCD73_RS06290	COG0081	regulation of translation
GCD73_RS06295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GCD73_RS06315	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GCD73_RS06340	COG1012	belongs to the aldehyde dehydrogenase family
GCD73_RS06375	COG0583	DNA-binding transcription factor activity
GCD73_RS06380	COG0252	asparaginase activity
GCD73_RS06385	COG1475	DNA binding
GCD73_RS06395	COG1192	Involved in chromosome partitioning
GCD73_RS06400	COG0357	Ribosomal RNA small subunit methyltransferase G
GCD73_RS06405	COG0445	tRNA wobble uridine modification
GCD73_RS06410	COG1278	Cold shock
GCD73_RS06415	COG3180	Ammonia monooxygenase
GCD73_RS06420	COG0436	Aminotransferase
GCD73_RS06450	COG0038	chloride channel
GCD73_RS06485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GCD73_RS06495	COG0601	transmembrane transport
GCD73_RS06500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS06505	COG0444	Belongs to the ABC transporter superfamily
GCD73_RS06510	COG4608	Belongs to the ABC transporter superfamily
GCD73_RS06515	COG1473	amidohydrolase
GCD73_RS06520	COG2175	clavaminate synthase activity
GCD73_RS06530	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GCD73_RS06540	COG0753	catalase activity
GCD73_RS06545	COG0706	membrane insertase activity
GCD73_RS06550	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GCD73_RS06555	COG0594	ribonuclease P activity
GCD73_RS06560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GCD73_RS06565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GCD73_RS06570	COG0592	DNA-directed DNA polymerase activity
GCD73_RS06580	COG0583	DNA-binding transcription factor activity
GCD73_RS06590	COG0765	amino acid transport
GCD73_RS06595	COG0765	amino acid transport
GCD73_RS06600	COG1126	abc transporter atp-binding protein
GCD73_RS06625	COG1304	FMN binding
GCD73_RS06635	COG3842	ATPase activity
GCD73_RS06640	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCD73_RS06645	COG1177	transmembrane transport
GCD73_RS06700	COG1609	Transcriptional regulator
GCD73_RS06710	COG3842	ATPase activity
GCD73_RS06715	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCD73_RS06720	COG1177	transmembrane transport
GCD73_RS06745	COG0251	oxidation-reduction process
GCD73_RS06750	COG0402	S-adenosylhomocysteine deaminase activity
GCD73_RS06755	COG1079	Belongs to the binding-protein-dependent transport system permease family
GCD73_RS06760	COG4603	Belongs to the binding-protein-dependent transport system permease family
GCD73_RS06765	COG3845	ABC transporter
GCD73_RS06770	COG1744	ABC transporter substrate-binding protein PnrA-like
GCD73_RS06780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCD73_RS06795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCD73_RS06820	COG3781	membrane
GCD73_RS06825	COG1522	sequence-specific DNA binding
GCD73_RS06830	COG0028	Belongs to the TPP enzyme family
GCD73_RS06835	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS06840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCD73_RS06845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCD73_RS06845	COG1116	anion transmembrane transporter activity
GCD73_RS06855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCD73_RS06855	COG0551	DNA topoisomerase type I activity
GCD73_RS06865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCD73_RS06870	COG2922	Belongs to the Smg family
GCD73_RS06880	COG2358	TRAP transporter, solute receptor (TAXI family
GCD73_RS06905	COG0765	amino acid transport
GCD73_RS06910	COG0765	amino acid transport
GCD73_RS06915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS06920	COG3547	Transposase (IS116 IS110 IS902 family)
GCD73_RS06925	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS06930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GCD73_RS06950	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GCD73_RS06990	COG3328	transposase activity
GCD73_RS07000	COG1595	DNA-templated transcription, initiation
GCD73_RS07005	COG0753	catalase activity
GCD73_RS07015	COG2186	Transcriptional regulator
GCD73_RS07020	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS07060	COG0477	Major facilitator Superfamily
GCD73_RS07070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GCD73_RS07075	COG0183	Belongs to the thiolase family
GCD73_RS07080	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GCD73_RS07085	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS07090	COG1473	amidohydrolase
GCD73_RS07095	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS07100	COG1742	UPF0060 membrane protein
GCD73_RS07110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCD73_RS07130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCD73_RS07155	COG0395	ABC-type sugar transport system, permease component
GCD73_RS07160	COG1175	transmembrane transport
GCD73_RS07165	COG1653	transport
GCD73_RS07175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCD73_RS07180	COG1609	Transcriptional regulator
GCD73_RS07185	COG0154	amidase activity
GCD73_RS07190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCD73_RS07200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GCD73_RS07210	COG0583	DNA-binding transcription factor activity
GCD73_RS07230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GCD73_RS07235	COG1280	lysine exporter protein (LysE YggA)
GCD73_RS07240	COG0513	Belongs to the DEAD box helicase family
GCD73_RS07245	COG5339	Protein conserved in bacteria
GCD73_RS07265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS07270	COG0601	transmembrane transport
GCD73_RS07275	COG4166	transmembrane transport
GCD73_RS07280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GCD73_RS07290	COG3708	Transcriptional regulator
GCD73_RS07290	COG2207	Transcriptional regulator
GCD73_RS07295	COG0697	spore germination
GCD73_RS07300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GCD73_RS07340	COG2969	positive regulation of protein catabolic process
GCD73_RS07345	COG0625	glutathione transferase activity
GCD73_RS07350	COG2857	Cytochrome c1
GCD73_RS07355	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GCD73_RS07360	COG0723	plastoquinol--plastocyanin reductase activity
GCD73_RS07365	COG1970	mechanosensitive ion channel activity
GCD73_RS07370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GCD73_RS07375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCD73_RS07390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCD73_RS07395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCD73_RS07400	COG0537	adenosine 5'-monophosphoramidase activity
GCD73_RS07405	COG0140	phosphoribosyl-ATP diphosphatase activity
GCD73_RS07410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GCD73_RS07415	COG0107	imidazoleglycerol-phosphate synthase activity
GCD73_RS07420	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GCD73_RS07425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GCD73_RS07430	COG0131	Imidazoleglycerol-phosphate dehydratase
GCD73_RS07435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GCD73_RS07440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GCD73_RS07445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GCD73_RS07450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GCD73_RS07460	COG0842	Transport permease protein
GCD73_RS07465	COG1131	(ABC) transporter
GCD73_RS07475	COG2853	Lipoprotein
GCD73_RS07480	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCD73_RS07485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GCD73_RS07490	COG1127	ABC transporter
GCD73_RS07495	COG2070	2-Nitropropane dioxygenase
GCD73_RS07505	COG0477	Major facilitator Superfamily
GCD73_RS07510	COG0583	DNA-binding transcription factor activity
GCD73_RS07515	COG3047	cAMP biosynthetic process
GCD73_RS07525	COG0069	glutamate synthase activity
GCD73_RS07525	COG0070	glutamate synthase
GCD73_RS07525	COG0067	glutamate synthase
GCD73_RS07550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCD73_RS07570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCD73_RS07600	COG1612	heme a metabolic process
GCD73_RS07610	COG1999	signal sequence binding
GCD73_RS07630	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GCD73_RS07635	COG2814	Major facilitator Superfamily
GCD73_RS07660	COG1522	sequence-specific DNA binding
GCD73_RS07685	COG2814	Major facilitator Superfamily
GCD73_RS07690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCD73_RS07695	COG3437	response regulator, receiver
GCD73_RS07700	COG0784	Response regulator, receiver
GCD73_RS07700	COG2205	protein histidine kinase activity
GCD73_RS07700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS07700	COG2198	Histidine kinase
GCD73_RS07765	COG0583	DNA-binding transcription factor activity
GCD73_RS07770	COG0840	transmembrane signaling receptor activity
GCD73_RS07775	COG0745	RESPONSE REGULATOR receiver
GCD73_RS07790	COG0789	Transcriptional regulator
GCD73_RS07795	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GCD73_RS07815	COG0583	DNA-binding transcription factor activity
GCD73_RS07820	COG0861	Integral membrane protein TerC family
GCD73_RS07860	COG0243	molybdopterin cofactor binding
GCD73_RS07865	COG0038	chloride channel
GCD73_RS07885	COG0154	amidase activity
GCD73_RS07890	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS07895	COG0583	DNA-binding transcription factor activity
GCD73_RS07900	COG0656	L-ascorbic acid biosynthetic process
GCD73_RS07905	COG0583	DNA-binding transcription factor activity
GCD73_RS07915	COG2814	Major facilitator Superfamily
GCD73_RS07920	COG0583	DNA-binding transcription factor activity
GCD73_RS07930	COG2423	ornithine cyclodeaminase activity
GCD73_RS07940	COG2200	EAL domain
GCD73_RS07965	COG5001	Diguanylate cyclase
GCD73_RS07970	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GCD73_RS08000	COG0840	transmembrane signaling receptor activity
GCD73_RS08005	COG2814	Major facilitator Superfamily
GCD73_RS08045	COG1802	Transcriptional regulator
GCD73_RS08055	COG3069	C4-dicarboxylate transmembrane transporter activity
GCD73_RS08060	COG1012	belongs to the aldehyde dehydrogenase family
GCD73_RS08070	COG0543	2 iron, 2 sulfur cluster binding
GCD73_RS08070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCD73_RS08080	COG3064	Membrane
GCD73_RS08105	COG1607	acyl-coa hydrolase
GCD73_RS08120	COG0437	4 iron, 4 sulfur cluster binding
GCD73_RS08125	COG2864	formate dehydrogenase
GCD73_RS08140	COG3276	selenocysteine insertion sequence binding
GCD73_RS08150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCD73_RS08155	COG1305	Transglutaminase-like
GCD73_RS08165	COG0583	DNA-binding transcription factor activity
GCD73_RS08190	COG1012	belongs to the aldehyde dehydrogenase family
GCD73_RS08195	COG3284	Transcriptional regulator
GCD73_RS08205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCD73_RS08210	COG0512	Glutamine amidotransferase of anthranilate synthase
GCD73_RS08220	COG0546	phosphoglycolate phosphatase activity
GCD73_RS08225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GCD73_RS08230	COG2967	ApaG domain
GCD73_RS08235	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GCD73_RS08240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCD73_RS08250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCD73_RS08255	COG0037	tRNA processing
GCD73_RS08290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCD73_RS08295	COG1024	Enoyl-CoA hydratase
GCD73_RS08310	COG0356	it plays a direct role in the translocation of protons across the membrane
GCD73_RS08320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GCD73_RS08325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GCD73_RS08330	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GCD73_RS08335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GCD73_RS08340	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GCD73_RS08345	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GCD73_RS08355	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GCD73_RS08360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GCD73_RS08365	COG0210	DNA helicase
GCD73_RS08370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GCD73_RS08380	COG2171	N-acyltransferase activity
GCD73_RS08385	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCD73_RS08395	COG4608	Belongs to the ABC transporter superfamily
GCD73_RS08405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS08410	COG0601	transmembrane transport
GCD73_RS08415	COG2988	succinylglutamate desuccinylase activity
GCD73_RS08420	COG0747	negative chemotaxis
GCD73_RS08430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GCD73_RS08435	COG1024	Enoyl-CoA hydratase
GCD73_RS08440	COG1024	Enoyl-CoA hydratase
GCD73_RS08465	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCD73_RS08480	COG0582	viral genome integration into host DNA
GCD73_RS08510	COG2916	Histone family protein nucleoid-structuring protein H-NS
GCD73_RS08585	COG1653	transport
GCD73_RS08590	COG0395	ABC-type sugar transport system, permease component
GCD73_RS08595	COG1175	transmembrane transport
GCD73_RS08600	COG3842	ATPase activity
GCD73_RS08605	COG0546	phosphoglycolate phosphatase activity
GCD73_RS08665	COG2003	Belongs to the UPF0758 family
GCD73_RS08700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GCD73_RS08735	COG1674	ftsk spoiiie
GCD73_RS08905	COG0583	DNA-binding transcription factor activity
GCD73_RS08955	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCD73_RS08960	COG1802	Transcriptional regulator
GCD73_RS08965	COG0583	DNA-binding transcription factor activity
GCD73_RS08985	COG2918	glutathione biosynthetic process
GCD73_RS09000	COG2197	response regulator
GCD73_RS09010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GCD73_RS09015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCD73_RS09025	COG2721	sulfolactate sulfo-lyase activity
GCD73_RS09030	COG2721	sulfolactate sulfo-lyase activity
GCD73_RS09035	COG2188	Transcriptional regulator
GCD73_RS09040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GCD73_RS09045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GCD73_RS09045	COG2813	Specifically methylates the guanine in position
GCD73_RS09050	COG2223	nitrite transmembrane transporter activity
GCD73_RS09065	COG2860	membrane
GCD73_RS09070	COG1802	Transcriptional regulator
GCD73_RS09080	COG1984	allophanate hydrolase subunit 2
GCD73_RS09085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GCD73_RS09095	COG0583	DNA-binding transcription factor activity
GCD73_RS09100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCD73_RS09115	COG2132	Multicopper oxidase
GCD73_RS09125	COG0642	Histidine kinase
GCD73_RS09140	COG0745	RESPONSE REGULATOR receiver
GCD73_RS09145	COG2226	methyltransferase
GCD73_RS09160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GCD73_RS09170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GCD73_RS09180	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GCD73_RS09185	COG0351	phosphomethylpyrimidine kinase
GCD73_RS09190	COG2022	thiamine diphosphate biosynthetic process
GCD73_RS09195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCD73_RS09200	COG4771	TonB-dependent receptor
GCD73_RS09215	COG2186	Transcriptional regulator
GCD73_RS09220	COG1063	alcohol dehydrogenase
GCD73_RS09225	COG4948	Mandelate Racemase Muconate Lactonizing
GCD73_RS09230	COG0246	Mannitol dehydrogenase
GCD73_RS09235	COG2226	methyltransferase
GCD73_RS09245	COG1194	a g-specific adenine glycosylase
GCD73_RS09280	COG0477	Major facilitator Superfamily
GCD73_RS09290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GCD73_RS09295	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GCD73_RS09315	COG0237	dephospho-CoA kinase activity
GCD73_RS09320	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GCD73_RS09345	COG0154	amidase activity
GCD73_RS09360	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GCD73_RS09435	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS09440	COG1024	Enoyl-CoA hydratase
GCD73_RS09480	COG4638	Rieske (2fe-2S)
GCD73_RS09485	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GCD73_RS09490	COG1335	isochorismatase
GCD73_RS09495	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS09505	COG0741	lytic transglycosylase activity
GCD73_RS09510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GCD73_RS09515	COG0352	thiamine-phosphate diphosphorylase activity
GCD73_RS09530	COG1678	Uncharacterized ACR, COG1678
GCD73_RS09535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GCD73_RS09555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GCD73_RS09565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCD73_RS09570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GCD73_RS09580	COG3842	ATPase activity
GCD73_RS09585	COG1175	transmembrane transport
GCD73_RS09605	COG0557	exoribonuclease II activity
GCD73_RS09610	COG3150	esterase
GCD73_RS09615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GCD73_RS09620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCD73_RS09625	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GCD73_RS09630	COG0511	ligase activity, forming carbon-carbon bonds
GCD73_RS09635	COG0439	Biotin carboxylase
GCD73_RS09640	COG2264	protein methyltransferase activity
GCD73_RS09675	COG1696	Membrane protein involved in D-alanine export
GCD73_RS09710	COG1522	sequence-specific DNA binding
GCD73_RS09715	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS09725	COG0583	DNA-binding transcription factor activity
GCD73_RS09740	COG3547	Transposase (IS116 IS110 IS902 family)
GCD73_RS09745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCD73_RS09750	COG1042	CoA-binding domain protein
GCD73_RS09750	COG0045	succinate-CoA ligase (ADP-forming) activity
GCD73_RS09750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCD73_RS09755	COG1335	isochorismatase
GCD73_RS09760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCD73_RS09765	COG1116	anion transmembrane transporter activity
GCD73_RS09785	COG0312	modulator of DNA gyrase
GCD73_RS09790	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GCD73_RS09800	COG0559	Belongs to the binding-protein-dependent transport system permease family
GCD73_RS09820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GCD73_RS09825	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GCD73_RS09830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GCD73_RS09840	COG0316	Belongs to the HesB IscA family
GCD73_RS09845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GCD73_RS09855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GCD73_RS09860	COG1881	PFAM PEBP family protein
GCD73_RS09865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GCD73_RS09870	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GCD73_RS09875	COG2207	Transcriptional regulator
GCD73_RS09885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCD73_RS09885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCD73_RS09890	COG2766	serine protein kinase
GCD73_RS09895	COG2718	Belongs to the UPF0229 family
GCD73_RS09900	COG2719	SpoVR family
GCD73_RS09915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCD73_RS09920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS09935	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS09960	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS09980	COG0741	lytic transglycosylase activity
GCD73_RS09980	COG1388	LysM domain
GCD73_RS09985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCD73_RS09990	COG2226	methyltransferase
GCD73_RS09995	COG0328	RNA-DNA hybrid ribonuclease activity
GCD73_RS10005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCD73_RS10010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCD73_RS10020	COG1671	Belongs to the UPF0178 family
GCD73_RS10035	COG0786	glutamate:sodium symporter activity
GCD73_RS10045	COG0463	Glycosyl transferase, family 2
GCD73_RS10050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GCD73_RS10065	COG0583	DNA-binding transcription factor activity
GCD73_RS10080	COG0583	DNA-binding transcription factor activity
GCD73_RS10090	COG1346	cytolysis
GCD73_RS10100	COG0697	spore germination
GCD73_RS10105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCD73_RS10120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GCD73_RS10130	COG1522	sequence-specific DNA binding
GCD73_RS10145	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GCD73_RS10150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCD73_RS10165	COG0823	Involved in the tonB-independent uptake of proteins
GCD73_RS10175	COG0848	biopolymer transport protein
GCD73_RS10180	COG0811	peptide transport
GCD73_RS10185	COG0824	Thioesterase
GCD73_RS10220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCD73_RS10235	COG2084	Dehydrogenase
GCD73_RS10240	COG0405	Gamma-glutamyltransferase
GCD73_RS10280	COG0129	dihydroxy-acid dehydratase activity
GCD73_RS10285	COG4654	Cytochrome c, class I
GCD73_RS10290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GCD73_RS10360	COG1473	amidohydrolase
GCD73_RS10365	COG0418	dihydroorotase activity
GCD73_RS10370	COG0488	(ABC) transporter
GCD73_RS10380	COG2001	Belongs to the MraZ family
GCD73_RS10385	COG0275	rRNA processing
GCD73_RS10390	COG3116	cell division
GCD73_RS10400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GCD73_RS10405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCD73_RS10410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GCD73_RS10420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GCD73_RS10425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GCD73_RS10430	COG1181	Belongs to the D-alanine--D-alanine ligase family
GCD73_RS10435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GCD73_RS10445	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GCD73_RS10450	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GCD73_RS10460	COG0739	heme binding
GCD73_RS10465	COG0653	protein targeting
GCD73_RS10480	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS10485	COG0028	Belongs to the TPP enzyme family
GCD73_RS10490	COG0300	oxidoreductase activity
GCD73_RS10495	COG1522	sequence-specific DNA binding
GCD73_RS10510	COG2239	Acts as a magnesium transporter
GCD73_RS10520	COG2855	membrane
GCD73_RS10535	COG1473	amidohydrolase
GCD73_RS10540	COG0318	PFAM AMP-dependent synthetase and ligase
GCD73_RS10545	COG0483	inositol monophosphate 1-phosphatase activity
GCD73_RS10550	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GCD73_RS10550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCD73_RS10555	COG1501	Belongs to the glycosyl hydrolase 31 family
GCD73_RS10560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GCD73_RS10565	COG2011	ABC-type metal ion transport system permease component
GCD73_RS10580	COG0582	viral genome integration into host DNA
GCD73_RS10630	COG0028	Belongs to the TPP enzyme family
GCD73_RS10645	COG0583	DNA-binding transcription factor activity
GCD73_RS10650	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS10690	COG2003	Belongs to the UPF0758 family
GCD73_RS10725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GCD73_RS10740	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GCD73_RS10760	COG1653	transport
GCD73_RS10765	COG0395	ABC-type sugar transport system, permease component
GCD73_RS10770	COG1175	transmembrane transport
GCD73_RS10780	COG0546	phosphoglycolate phosphatase activity
GCD73_RS11005	COG2610	gluconate transmembrane transporter activity
GCD73_RS11020	COG0735	belongs to the Fur family
GCD73_RS11035	COG2818	Glycosylase
GCD73_RS11040	COG1368	sulfuric ester hydrolase activity
GCD73_RS11045	COG2982	Protein involved in outer membrane biogenesis
GCD73_RS11055	COG1309	transcriptional regulator
GCD73_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS11080	COG2154	pterin-4-alpha-carbinolamine dehydratase
GCD73_RS11095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCD73_RS11105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GCD73_RS11120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCD73_RS11125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GCD73_RS11130	COG1929	Belongs to the glycerate kinase type-1 family
GCD73_RS11135	COG0469	pyruvate kinase activity
GCD73_RS11140	COG0700	Nucleoside recognition
GCD73_RS11150	COG0242	peptide deformylase activity
GCD73_RS11170	COG0204	Acyl-transferase
GCD73_RS11175	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCD73_RS11180	COG0751	glycine-tRNA ligase activity
GCD73_RS11185	COG0752	glycyl-tRNA synthetase alpha subunit
GCD73_RS11190	COG1024	Enoyl-CoA hydratase
GCD73_RS11200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCD73_RS11205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS11210	COG2030	dehydratase
GCD73_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS11245	COG0318	PFAM AMP-dependent synthetase and ligase
GCD73_RS11260	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS11265	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS11270	COG1024	Enoyl-CoA hydratase
GCD73_RS11275	COG0583	DNA-binding transcription factor activity
GCD73_RS11280	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
GCD73_RS11285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS11290	COG2301	Belongs to the HpcH HpaI aldolase family
GCD73_RS11295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCD73_RS11305	COG0617	tRNA 3'-terminal CCA addition
GCD73_RS11320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GCD73_RS11325	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GCD73_RS11330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GCD73_RS11335	COG0586	Pfam SNARE associated Golgi protein
GCD73_RS11340	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCD73_RS11345	COG0802	atpase or kinase
GCD73_RS11350	COG0114	fumarate hydratase activity
GCD73_RS11360	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS11370	COG0405	Gamma-glutamyltransferase
GCD73_RS11375	COG0531	amino acid
GCD73_RS11380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS11390	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS11395	COG0583	DNA-binding transcription factor activity
GCD73_RS11405	COG0579	oxidoreductase
GCD73_RS11415	COG0259	pyridoxamine-phosphate oxidase activity
GCD73_RS11430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCD73_RS11435	COG1136	(ABC) transporter
GCD73_RS11435	COG0577	efflux transmembrane transporter activity
GCD73_RS11440	COG1538	Outer membrane efflux protein
GCD73_RS11445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GCD73_RS11480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCD73_RS11490	COG0800	Aldolase
GCD73_RS11510	COG0463	Glycosyl transferase, family 2
GCD73_RS11510	COG1216	Glycosyl transferase, family 2
GCD73_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS11540	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GCD73_RS11565	COG4638	Rieske (2fe-2S)
GCD73_RS11590	COG0747	negative chemotaxis
GCD73_RS11595	COG0601	transmembrane transport
GCD73_RS11600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS11605	COG0444	Belongs to the ABC transporter superfamily
GCD73_RS11610	COG4608	Belongs to the ABC transporter superfamily
GCD73_RS11625	COG0488	(ABC) transporter
GCD73_RS11640	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GCD73_RS11645	COG2894	cell division
GCD73_RS11650	COG0850	regulation of cytokinetic process
GCD73_RS11655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCD73_RS11665	COG1294	oxidase, subunit
GCD73_RS11670	COG0514	ATP-dependent DNA helicase (RecQ)
GCD73_RS11685	COG4191	Histidine kinase
GCD73_RS11690	COG2255	four-way junction helicase activity
GCD73_RS11700	COG1090	epimerase
GCD73_RS11705	COG0632	four-way junction helicase activity
GCD73_RS11710	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GCD73_RS11730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCD73_RS11740	COG0006	proline dipeptidase activity
GCD73_RS11755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GCD73_RS11760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCD73_RS11775	COG4783	chaperone-mediated protein folding
GCD73_RS11780	COG0429	hydrolase of the alpha beta-hydrolase fold
GCD73_RS11810	COG0513	Belongs to the DEAD box helicase family
GCD73_RS11825	COG1546	Belongs to the CinA family
GCD73_RS11825	COG1058	Belongs to the CinA family
GCD73_RS11830	COG1414	Transcriptional regulator
GCD73_RS11845	COG0167	dihydroorotate dehydrogenase activity
GCD73_RS11850	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GCD73_RS11855	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GCD73_RS11940	COG0629	single-stranded DNA binding
GCD73_RS11945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCD73_RS11960	COG0789	Transcriptional regulator
GCD73_RS11970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GCD73_RS12015	COG0789	Transcriptional regulator
GCD73_RS12105	COG0431	NADPH-dependent FMN reductase
GCD73_RS12110	COG1393	Belongs to the ArsC family
GCD73_RS12115	COG0798	PFAM Bile acid sodium symporter
GCD73_RS12215	COG2003	Belongs to the UPF0758 family
GCD73_RS12275	COG5002	protein histidine kinase activity
GCD73_RS12280	COG0745	RESPONSE REGULATOR receiver
GCD73_RS12285	COG2132	Multicopper oxidase
GCD73_RS12325	COG0583	DNA-binding transcription factor activity
GCD73_RS12330	COG1396	sequence-specific DNA binding
GCD73_RS12345	COG3039	Transposase
GCD73_RS12360	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCD73_RS12370	COG0582	viral genome integration into host DNA
GCD73_RS12395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCD73_RS12400	COG0735	belongs to the Fur family
GCD73_RS12405	COG0497	DNA recombination
GCD73_RS12415	COG1420	regulation of RNA biosynthetic process
GCD73_RS12420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GCD73_RS12430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GCD73_RS12440	COG0443	Heat shock 70 kDa protein
GCD73_RS12445	COG0484	heat shock protein binding
GCD73_RS12460	COG0612	Peptidase, M16
GCD73_RS12485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GCD73_RS12515	COG0840	transmembrane signaling receptor activity
GCD73_RS12535	COG0745	RESPONSE REGULATOR receiver
GCD73_RS12540	COG2205	protein histidine kinase activity
GCD73_RS12545	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GCD73_RS12550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GCD73_RS12555	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GCD73_RS12570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GCD73_RS12580	COG1193	negative regulation of DNA recombination
GCD73_RS12585	COG0492	ferredoxin-NADP+ reductase activity
GCD73_RS12590	COG1674	ftsk spoiiie
GCD73_RS12595	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GCD73_RS12605	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GCD73_RS12610	COG0517	IMP dehydrogenase activity
GCD73_RS12610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GCD73_RS12630	COG0601	transmembrane transport
GCD73_RS12635	COG0747	negative chemotaxis
GCD73_RS12645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCD73_RS12650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GCD73_RS12655	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GCD73_RS12705	COG0477	Major facilitator Superfamily
GCD73_RS12710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCD73_RS12715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCD73_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS12740	COG3022	response to hydroperoxide
GCD73_RS12745	COG1289	transmembrane transporter activity
GCD73_RS12750	COG0028	Belongs to the TPP enzyme family
GCD73_RS12755	COG0440	acetolactate synthase activity
GCD73_RS12760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GCD73_RS12765	COG1183	phosphatidylcholine synthase activity
GCD73_RS12775	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GCD73_RS12780	COG1185	polyribonucleotide nucleotidyltransferase activity
GCD73_RS12790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCD73_RS12820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS12830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCD73_RS12845	COG0604	alcohol dehydrogenase
GCD73_RS12845	COG3321	synthase
GCD73_RS12850	COG0149	triose-phosphate isomerase activity
GCD73_RS12855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCD73_RS12860	COG0583	DNA-binding transcription factor activity
GCD73_RS12865	COG5383	Protein conserved in bacteria
GCD73_RS12925	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GCD73_RS12930	COG4608	Belongs to the ABC transporter superfamily
GCD73_RS12935	COG0444	Belongs to the ABC transporter superfamily
GCD73_RS12940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS12945	COG0601	transmembrane transport
GCD73_RS12950	COG0747	negative chemotaxis
GCD73_RS13050	COG2207	Transcriptional regulator
GCD73_RS13055	COG4221	oxidoreductase activity
GCD73_RS13080	COG2851	Citrate transporter
GCD73_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS13095	COG3119	arylsulfatase activity
GCD73_RS13100	COG0583	DNA-binding transcription factor activity
GCD73_RS13120	COG1278	Cold shock
GCD73_RS13130	COG3604	Transcriptional regulator
GCD73_RS13135	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GCD73_RS13145	COG2354	Protein conserved in bacteria
GCD73_RS13155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCD73_RS13160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCD73_RS13170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCD73_RS13175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCD73_RS13180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCD73_RS13195	COG0583	DNA-binding transcription factor activity
GCD73_RS13210	COG1597	lipid kinase activity
GCD73_RS13215	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCD73_RS13225	COG0287	Prephenate dehydrogenase
GCD73_RS13240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCD73_RS13245	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCD73_RS13250	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCD73_RS13255	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCD73_RS13260	COG0649	NAD binding
GCD73_RS13265	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GCD73_RS13275	COG1034	ATP synthesis coupled electron transport
GCD73_RS13280	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GCD73_RS13285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCD73_RS13295	COG0713	ATP synthesis coupled electron transport
GCD73_RS13310	COG1007	ATP synthesis coupled electron transport
GCD73_RS13320	COG4774	siderophore transport
GCD73_RS13325	COG0560	Phosphoserine phosphatase
GCD73_RS13330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GCD73_RS13335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GCD73_RS13340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GCD73_RS13350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCD73_RS13355	COG0450	alkyl hydroperoxide reductase
GCD73_RS13370	COG1214	PFAM Peptidase M22, glycoprotease
GCD73_RS13375	COG1573	uracil-dna glycosylase
GCD73_RS13380	COG0477	Major facilitator Superfamily
GCD73_RS13385	COG1196	nuclear chromosome segregation
GCD73_RS13395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GCD73_RS13400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCD73_RS13410	COG2917	probably involved in intracellular septation
GCD73_RS13415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GCD73_RS13420	COG1122	ATPase activity
GCD73_RS13425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GCD73_RS13430	COG1268	BioY protein
GCD73_RS13460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCD73_RS13495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GCD73_RS13500	COG2878	Part of a membrane complex involved in electron transport
GCD73_RS13515	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GCD73_RS13520	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GCD73_RS13525	COG0251	oxidation-reduction process
GCD73_RS13535	COG3228	Belongs to the MtfA family
GCD73_RS13540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCD73_RS13550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GCD73_RS13560	COG0159	tryptophan synthase activity
GCD73_RS13565	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GCD73_RS13570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCD73_RS13575	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS13580	COG2721	sulfolactate sulfo-lyase activity
GCD73_RS13595	COG1530	ribonuclease E activity
GCD73_RS13600	COG0564	pseudouridine synthase activity
GCD73_RS13610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GCD73_RS13615	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GCD73_RS13620	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCD73_RS13630	COG0424	maF-like protein
GCD73_RS13635	COG1399	metal-binding, possibly nucleic acid-binding protein
GCD73_RS13640	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GCD73_RS13645	COG0416	fatty acid biosynthetic process
GCD73_RS13650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GCD73_RS13655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GCD73_RS13660	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS13665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCD73_RS13670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCD73_RS13695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCD73_RS13705	COG0681	Belongs to the peptidase S26 family
GCD73_RS13710	COG0571	ribonuclease III activity
GCD73_RS13715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GCD73_RS13720	COG1381	Involved in DNA repair and RecF pathway recombination
GCD73_RS13770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GCD73_RS13795	COG0583	DNA-binding transcription factor activity
GCD73_RS13805	COG0791	NLP P60 protein
GCD73_RS13815	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GCD73_RS13825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GCD73_RS13830	COG0697	spore germination
GCD73_RS13835	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GCD73_RS13850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GCD73_RS13875	COG2153	protein acetylation
GCD73_RS13885	COG1446	asparaginase
GCD73_RS13890	COG4172	Belongs to the ABC transporter superfamily
GCD73_RS13895	COG0747	negative chemotaxis
GCD73_RS13905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS13930	COG0504	CTP synthase activity
GCD73_RS13945	COG0148	phosphopyruvate hydratase activity
GCD73_RS13960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GCD73_RS13970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GCD73_RS14000	COG1981	membrane
GCD73_RS14020	COG0039	L-malate dehydrogenase activity
GCD73_RS14025	COG2188	Transcriptional regulator
GCD73_RS14030	COG2009	succinate dehydrogenase
GCD73_RS14035	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GCD73_RS14040	COG1053	succinate dehydrogenase
GCD73_RS14045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GCD73_RS14050	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GCD73_RS14055	COG0372	Belongs to the citrate synthase family
GCD73_RS14060	COG3539	Fimbrial protein
GCD73_RS14070	COG3121	Chaperone
GCD73_RS14075	COG3539	Fimbrial protein
GCD73_RS14090	COG0280	phosphate acetyltransferase
GCD73_RS14090	COG0281	malic enzyme
GCD73_RS14100	COG1297	OPT oligopeptide transporter protein
GCD73_RS14105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GCD73_RS14120	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GCD73_RS14130	COG1522	sequence-specific DNA binding
GCD73_RS14135	COG0567	Dehydrogenase, E1 component
GCD73_RS14140	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCD73_RS14145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCD73_RS14150	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GCD73_RS14155	COG1595	DNA-templated transcription, initiation
GCD73_RS14160	COG3712	iron ion homeostasis
GCD73_RS14165	COG4774	siderophore transport
GCD73_RS14190	COG2183	response to ionizing radiation
GCD73_RS14195	COG1199	ATP-dependent helicase activity
GCD73_RS14205	COG0564	pseudouridine synthase activity
GCD73_RS14215	COG3243	poly(R)-hydroxyalkanoic acid synthase
GCD73_RS14220	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS14225	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
GCD73_RS14240	COG0672	)-iron permease
GCD73_RS14255	COG2823	Periplasmic or secreted lipoprotein
GCD73_RS14265	COG3237	CsbD-like
GCD73_RS14275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GCD73_RS14275	COG0189	ligase activity
GCD73_RS14280	COG1132	(ABC) transporter
GCD73_RS14295	COG2833	Protein of unknown function (DUF455)
GCD73_RS14300	COG2258	MOSC domain
GCD73_RS14305	COG2951	lytic endotransglycosylase activity
GCD73_RS14355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCD73_RS14370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GCD73_RS14380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GCD73_RS14390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GCD73_RS14395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GCD73_RS14415	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GCD73_RS14420	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GCD73_RS14425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCD73_RS14440	COG2951	lytic endotransglycosylase activity
GCD73_RS14470	COG2985	domain, Protein
GCD73_RS14475	COG0450	alkyl hydroperoxide reductase
GCD73_RS14490	COG4208	sulfate ABC transporter
GCD73_RS14495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GCD73_RS14500	COG0175	sulfate reduction
GCD73_RS14530	COG0335	large ribosomal subunit rRNA binding
GCD73_RS14540	COG1162	GTPase activity
GCD73_RS14545	COG0501	Belongs to the peptidase M48B family
GCD73_RS14550	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GCD73_RS14555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GCD73_RS14560	COG3327	negative regulation of DNA-templated transcription, initiation
GCD73_RS14565	COG3396	Phenylacetate-CoA oxygenase
GCD73_RS14570	COG3460	Phenylacetate-CoA oxygenase
GCD73_RS14575	COG3396	Phenylacetate-CoA oxygenase
GCD73_RS14580	COG2151	metal-sulfur cluster biosynthetic enzyme
GCD73_RS14585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCD73_RS14590	COG1012	belongs to the aldehyde dehydrogenase family
GCD73_RS14595	COG1024	Enoyl-CoA hydratase
GCD73_RS14600	COG2050	protein possibly involved in aromatic compounds catabolism
GCD73_RS14625	COG3483	tryptophan 2,3-dioxygenase activity
GCD73_RS14630	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GCD73_RS14635	COG2003	Belongs to the UPF0758 family
GCD73_RS14645	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GCD73_RS14650	COG0625	glutathione transferase activity
GCD73_RS14655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCD73_RS14660	COG0642	Histidine kinase
GCD73_RS14680	COG0523	cobalamin synthesis protein
GCD73_RS14685	COG0583	DNA-binding transcription factor activity
GCD73_RS14700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GCD73_RS14705	COG1187	pseudouridine synthase activity
GCD73_RS14710	COG0779	Required for maturation of 30S ribosomal subunits
GCD73_RS14715	COG2251	uridine kinase activity
GCD73_RS14715	COG0195	Participates in both transcription termination and antitermination
GCD73_RS14720	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GCD73_RS14725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GCD73_RS14730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GCD73_RS14735	COG1217	gtp-binding protein TYPA
GCD73_RS14745	COG0583	DNA-binding transcription factor activity
GCD73_RS14760	COG0428	transporter
GCD73_RS14770	COG1283	sodium-dependent phosphate transmembrane transporter activity
GCD73_RS14775	COG1760	l-serine dehydratase
GCD73_RS14780	COG0501	Belongs to the peptidase M48B family
GCD73_RS14805	COG3842	ATPase activity
GCD73_RS14815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCD73_RS14820	COG1840	ABC-type Fe3 transport system, periplasmic component
GCD73_RS14825	COG0492	ferredoxin-NADP+ reductase activity
GCD73_RS14840	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS14850	COG1722	exodeoxyribonuclease VII activity
GCD73_RS14855	COG0142	geranyltranstransferase activity
GCD73_RS14865	COG1469	GTP cyclohydrolase I activity
GCD73_RS14870	COG3739	integral membrane protein
GCD73_RS14875	COG0360	Binds together with S18 to 16S ribosomal RNA
GCD73_RS14880	COG2965	DNA replication, synthesis of RNA primer
GCD73_RS14885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GCD73_RS14890	COG0359	binds to the 23S rRNA
GCD73_RS14900	COG0305	Participates in initiation and elongation during chromosome replication
GCD73_RS14910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GCD73_RS14945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCD73_RS14995	COG0540	Belongs to the ATCase OTCase family
GCD73_RS15000	COG3706	GGDEF domain
GCD73_RS15030	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GCD73_RS15035	COG2137	regulation of response to DNA damage stimulus
GCD73_RS15055	COG0045	succinate-CoA ligase (ADP-forming) activity
GCD73_RS15060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GCD73_RS15065	COG0861	Integral membrane protein TerC family
GCD73_RS15070	COG0861	Integral membrane protein TerC family
GCD73_RS15075	COG0181	hydroxymethylbilane synthase activity
GCD73_RS15110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GCD73_RS15115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCD73_RS15125	COG0436	Aminotransferase
GCD73_RS15145	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GCD73_RS15150	COG0308	aminopeptidase N
GCD73_RS15165	COG0312	modulator of DNA gyrase
GCD73_RS15170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCD73_RS15175	COG0277	FAD linked oxidase domain protein
GCD73_RS15180	COG0277	FAD linked oxidase domain protein
GCD73_RS15185	COG0277	FAD linked oxidase domain protein
GCD73_RS15190	COG0247	lactate metabolic process
GCD73_RS15215	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS15220	COG0583	DNA-binding transcription factor activity
GCD73_RS15225	COG0482	sulfurtransferase activity
GCD73_RS15230	COG0730	response to heat
GCD73_RS15235	COG0625	glutathione transferase activity
GCD73_RS15245	COG3909	cytochrome
GCD73_RS15320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GCD73_RS15335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCD73_RS15340	COG0069	glutamate synthase activity
GCD73_RS15345	COG2391	methyltransferase activity
GCD73_RS15380	COG0557	exoribonuclease II activity
GCD73_RS15385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCD73_RS15395	COG3128	pkhd-type hydroxylase
GCD73_RS15400	COG0776	regulation of translation
GCD73_RS15430	COG0642	Histidine kinase
GCD73_RS15435	COG3158	transport of potassium into the cell
GCD73_RS15440	COG0137	argininosuccinate synthase activity
GCD73_RS15445	COG0583	DNA-binding transcription factor activity
GCD73_RS15470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GCD73_RS15475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GCD73_RS15485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GCD73_RS15485	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GCD73_RS15495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCD73_RS15500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GCD73_RS15510	COG3642	lipopolysaccharide core region biosynthetic process
GCD73_RS15520	COG3842	ATPase activity
GCD73_RS15525	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCD73_RS15530	COG1177	transmembrane transport
GCD73_RS15560	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS15565	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GCD73_RS15570	COG0704	Plays a role in the regulation of phosphate uptake
GCD73_RS15580	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GCD73_RS15585	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GCD73_RS15585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GCD73_RS15590	COG0765	amino acid transport
GCD73_RS15595	COG0765	amino acid transport
GCD73_RS15605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS15620	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS15625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCD73_RS15630	COG0583	DNA-binding transcription factor activity
GCD73_RS15640	COG0277	FAD linked oxidase domain protein
GCD73_RS15645	COG1643	Atp-dependent helicase
GCD73_RS15660	COG0438	transferase activity, transferring glycosyl groups
GCD73_RS15665	COG0726	polysaccharide deacetylase
GCD73_RS15680	COG0726	polysaccharide deacetylase
GCD73_RS15705	COG1132	(ABC) transporter
GCD73_RS15710	COG0475	glutathione-regulated potassium exporter activity
GCD73_RS15710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCD73_RS15730	COG1530	ribonuclease E activity
GCD73_RS15760	COG2204	response regulator
GCD73_RS15765	COG4191	Histidine kinase
GCD73_RS15770	COG1301	dicarboxylic acid transport
GCD73_RS15780	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GCD73_RS15785	COG0799	negative regulation of ribosome biogenesis
GCD73_RS15790	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GCD73_RS15800	COG0151	Belongs to the GarS family
GCD73_RS15805	COG0217	transcriptional regulatory protein
GCD73_RS15810	COG0433	COG0433 Predicted ATPase
GCD73_RS15815	COG0473	3-isopropylmalate dehydrogenase activity
GCD73_RS15830	COG2814	Major facilitator Superfamily
GCD73_RS15835	COG1566	PFAM secretion protein HlyD family protein
GCD73_RS15865	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GCD73_RS15870	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GCD73_RS15880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GCD73_RS15905	COG2311	Membrane
GCD73_RS15910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GCD73_RS15935	COG0662	Cupin 2, conserved barrel domain protein
GCD73_RS15940	COG5285	phytanoyl-CoA dioxygenase
GCD73_RS15945	COG3217	Mosc domain protein beta barrel domain protein
GCD73_RS15945	COG0633	Ferredoxin
GCD73_RS15950	COG2076	Multidrug Resistance protein
GCD73_RS15965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCD73_RS15995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GCD73_RS16015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GCD73_RS16020	COG0425	Belongs to the sulfur carrier protein TusA family
GCD73_RS16030	COG0228	four-way junction DNA binding
GCD73_RS16035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GCD73_RS16040	COG0336	Belongs to the RNA methyltransferase TrmD family
GCD73_RS16045	COG1396	sequence-specific DNA binding
GCD73_RS16050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS16055	COG0765	amino acid transport
GCD73_RS16060	COG1126	abc transporter atp-binding protein
GCD73_RS16065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCD73_RS16070	COG0525	valine-tRNA ligase activity
GCD73_RS16075	COG0105	UTP biosynthetic process
GCD73_RS16080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GCD73_RS16100	COG2976	Protein conserved in bacteria
GCD73_RS16105	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCD73_RS16110	COG1160	GTP binding
GCD73_RS16115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GCD73_RS16120	COG1923	regulation of RNA biosynthetic process
GCD73_RS16125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GCD73_RS16130	COG0330	HflC and HflK could
GCD73_RS16135	COG0330	HflC and HflK could
GCD73_RS16140	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GCD73_RS16145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GCD73_RS16150	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GCD73_RS16155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GCD73_RS16165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCD73_RS16205	COG4964	Belongs to the GSP D family
GCD73_RS16230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCD73_RS16235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCD73_RS16245	COG1295	ribonuclease BN
GCD73_RS16255	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GCD73_RS16265	COG2205	protein histidine kinase activity
GCD73_RS16280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GCD73_RS16285	COG4783	chaperone-mediated protein folding
GCD73_RS16310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCD73_RS16315	COG2274	protein secretion by the type I secretion system
GCD73_RS16325	COG1538	Outer membrane efflux protein
GCD73_RS16345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCD73_RS16355	COG0101	tRNA pseudouridine synthase activity
GCD73_RS16360	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GCD73_RS16365	COG0135	phosphoribosylanthranilate isomerase activity
GCD73_RS16385	COG0129	dihydroxy-acid dehydratase activity
GCD73_RS16390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCD73_RS16395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GCD73_RS16400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GCD73_RS16405	COG1609	Transcriptional regulator
GCD73_RS16425	COG4172	Belongs to the ABC transporter superfamily
GCD73_RS16430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS16435	COG0601	transmembrane transport
GCD73_RS16460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCD73_RS16465	COG2197	response regulator
GCD73_RS16470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GCD73_RS16475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GCD73_RS16490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCD73_RS16495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCD73_RS16500	COG0004	ammonium transporteR
GCD73_RS16505	COG0347	Belongs to the P(II) protein family
GCD73_RS16510	COG2960	long-chain fatty acid transporting porin activity
GCD73_RS16515	COG0606	chelatase, subunit chli
GCD73_RS16520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GCD73_RS16525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GCD73_RS16530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GCD73_RS16535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCD73_RS16535	COG0072	phenylalanine-tRNA ligase activity
GCD73_RS16555	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GCD73_RS16590	COG0384	phenazine biosynthesis protein PhzF
GCD73_RS16595	COG0456	acetyltransferase
GCD73_RS16620	COG1522	sequence-specific DNA binding
GCD73_RS16660	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS16675	COG0583	DNA-binding transcription factor activity
GCD73_RS16690	COG5265	(ABC) transporter
GCD73_RS16695	COG0656	L-ascorbic acid biosynthetic process
GCD73_RS16710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GCD73_RS16725	COG2223	nitrite transmembrane transporter activity
GCD73_RS16755	COG1610	YqeY-like protein
GCD73_RS16765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCD73_RS16770	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS16780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCD73_RS16820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GCD73_RS16830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCD73_RS16835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCD73_RS16850	COG2091	lysine biosynthetic process via aminoadipic acid
GCD73_RS16865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCD73_RS16875	COG0506	proline dehydrogenase activity
GCD73_RS16890	COG0583	DNA-binding transcription factor activity
GCD73_RS16900	COG0625	glutathione transferase activity
GCD73_RS16915	COG2814	Major facilitator Superfamily
GCD73_RS16920	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS16925	COG0318	PFAM AMP-dependent synthetase and ligase
GCD73_RS16950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCD73_RS16960	COG3245	cytochrome
GCD73_RS16965	COG1280	lysine exporter protein (LysE YggA)
GCD73_RS16980	COG1280	lysine exporter protein (LysE YggA)
GCD73_RS17000	COG0697	spore germination
GCD73_RS17005	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GCD73_RS17010	COG0697	spore germination
GCD73_RS17025	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GCD73_RS17030	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS17040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GCD73_RS17045	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GCD73_RS17050	COG0667	Aldo Keto reductase
GCD73_RS17055	COG0583	DNA-binding transcription factor activity
GCD73_RS17075	COG0583	DNA-binding transcription factor activity
GCD73_RS17115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCD73_RS17125	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GCD73_RS17145	COG4133	protoheme IX ABC transporter activity
GCD73_RS17150	COG3005	denitrification pathway
GCD73_RS17155	COG3043	anaerobic respiration
GCD73_RS17160	COG0243	molybdopterin cofactor binding
GCD73_RS17175	COG3246	L-lysine catabolic process to acetate
GCD73_RS17180	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCD73_RS17185	COG0583	DNA-binding transcription factor activity
GCD73_RS17190	COG4774	siderophore transport
GCD73_RS17200	COG1595	DNA-templated transcription, initiation
GCD73_RS17210	COG0129	dihydroxy-acid dehydratase activity
GCD73_RS17215	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS17220	COG5001	Diguanylate cyclase
GCD73_RS17240	COG1024	Enoyl-CoA hydratase
GCD73_RS17245	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS17250	COG0583	DNA-binding transcription factor activity
GCD73_RS17255	COG2610	gluconate transmembrane transporter activity
GCD73_RS17275	COG2188	Transcriptional regulator
GCD73_RS17280	COG0318	PFAM AMP-dependent synthetase and ligase
GCD73_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS17300	COG4977	sequence-specific DNA binding
GCD73_RS17310	COG5265	(ABC) transporter
GCD73_RS17315	COG1132	(ABC) transporter
GCD73_RS17330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCD73_RS17340	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS17370	COG0583	DNA-binding transcription factor activity
GCD73_RS17410	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GCD73_RS17570	COG4626	Terminase
GCD73_RS17570	COG1802	Transcriptional regulator
GCD73_RS17575	COG4695	Portal protein
GCD73_RS17700	COG2186	Transcriptional regulator
GCD73_RS17710	COG0307	riboflavin synthase, alpha
GCD73_RS17720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCD73_RS17740	COG2207	Transcriptional regulator
GCD73_RS17740	COG4753	response regulator
GCD73_RS17750	COG0789	Transcriptional regulator
GCD73_RS17765	COG0022	dehydrogenase e1 component
GCD73_RS17785	COG0165	Argininosuccinate lyase
GCD73_RS17790	COG0668	transmembrane transport
GCD73_RS17850	COG2165	general secretion pathway protein
GCD73_RS17880	COG0583	DNA-binding transcription factor activity
GCD73_RS17890	COG0747	negative chemotaxis
GCD73_RS17895	COG0601	transmembrane transport
GCD73_RS17900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS17905	COG4172	Belongs to the ABC transporter superfamily
GCD73_RS17910	COG1280	lysine exporter protein (LysE YggA)
GCD73_RS17925	COG0300	oxidoreductase activity
GCD73_RS17940	COG2188	Transcriptional regulator
GCD73_RS17970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GCD73_RS17975	COG0066	3-isopropylmalate dehydratase activity
GCD73_RS18005	COG3161	chorismate lyase activity
GCD73_RS18010	COG1187	pseudouridine synthase activity
GCD73_RS18015	COG0583	DNA-binding transcription factor activity
GCD73_RS18040	COG1999	signal sequence binding
GCD73_RS18045	COG0339	signal peptide processing
GCD73_RS18050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GCD73_RS18055	COG4566	intracellular signal transduction
GCD73_RS18070	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCD73_RS18075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCD73_RS18080	COG2807	transmembrane transport
GCD73_RS18085	COG1846	Transcriptional regulator
GCD73_RS18120	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GCD73_RS18130	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GCD73_RS18145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCD73_RS18145	COG4797	methyltransferase
GCD73_RS18150	COG1191	sigma factor activity
GCD73_RS18175	COG0745	RESPONSE REGULATOR receiver
GCD73_RS18185	COG0835	chemotaxis
GCD73_RS18190	COG0840	transmembrane signaling receptor activity
GCD73_RS18195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GCD73_RS18200	COG2201	protein-glutamate methylesterase activity
GCD73_RS18205	COG0745	RESPONSE REGULATOR receiver
GCD73_RS18210	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GCD73_RS18220	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCD73_RS18225	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCD73_RS18240	COG2747	anti-sigma28 factor FlgM
GCD73_RS18255	COG1558	bacterial-type flagellum-dependent cell motility
GCD73_RS18265	COG1749	Flagellar hook protein flgE
GCD73_RS18270	COG4787	bacterial-type flagellum-dependent cell motility
GCD73_RS18290	COG1705	Flagellar rod assembly protein muramidase FlgJ
GCD73_RS18290	COG3951	Flagellar rod assembly protein muramidase FlgJ
GCD73_RS18310	COG0840	transmembrane signaling receptor activity
GCD73_RS18320	COG0840	transmembrane signaling receptor activity
GCD73_RS18325	COG0840	transmembrane signaling receptor activity
GCD73_RS18335	COG1987	bacterial-type flagellum assembly
GCD73_RS18380	COG1317	bacterial-type flagellum organization
GCD73_RS18385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCD73_RS18395	COG1677	Flagellar hook-basal body complex protein FliE
GCD73_RS18405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCD73_RS18425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GCD73_RS18445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS18460	COG0285	dihydrofolate synthase activity
GCD73_RS18480	COG1451	nucleotide metabolic process
GCD73_RS18485	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GCD73_RS18495	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GCD73_RS18500	COG0024	Methionine aminopeptidase
GCD73_RS18505	COG0052	Belongs to the universal ribosomal protein uS2 family
GCD73_RS18510	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GCD73_RS18515	COG0528	UMP kinase activity
GCD73_RS18520	COG0233	cytoplasmic translational termination
GCD73_RS18525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GCD73_RS18530	COG0575	Belongs to the CDS family
GCD73_RS18535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GCD73_RS18540	COG0750	zinc metalloprotease
GCD73_RS18545	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCD73_RS18550	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GCD73_RS18555	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GCD73_RS18560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GCD73_RS18575	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GCD73_RS18580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCD73_RS18615	COG2169	Transcriptional regulator
GCD73_RS18615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCD73_RS18620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GCD73_RS18620	COG0519	Catalyzes the synthesis of GMP from XMP
GCD73_RS18630	COG0330	HflC and HflK could
GCD73_RS18640	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GCD73_RS18645	COG2867	negative regulation of translational initiation
GCD73_RS18655	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS18660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GCD73_RS18680	COG0354	folic acid binding
GCD73_RS18685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GCD73_RS18690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GCD73_RS18695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GCD73_RS18700	COG0084	hydrolase, TatD family'
GCD73_RS18715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS18720	COG0765	amino acid transport
GCD73_RS18725	COG1126	abc transporter atp-binding protein
GCD73_RS18730	COG0010	Belongs to the arginase family
GCD73_RS18735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GCD73_RS18760	COG0625	glutathione transferase activity
GCD73_RS18770	COG1522	sequence-specific DNA binding
GCD73_RS18775	COG0386	Belongs to the glutathione peroxidase family
GCD73_RS18785	COG0840	transmembrane signaling receptor activity
GCD73_RS18795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS18815	COG0513	Belongs to the DEAD box helicase family
GCD73_RS18825	COG1414	Transcriptional regulator
GCD73_RS18840	COG0747	negative chemotaxis
GCD73_RS18845	COG0601	transmembrane transport
GCD73_RS18850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS18860	COG4608	Belongs to the ABC transporter superfamily
GCD73_RS18865	COG1228	amidohydrolase
GCD73_RS18890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCD73_RS18895	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GCD73_RS18900	COG4521	taurine ABC transporter
GCD73_RS18920	COG1966	Carbon starvation protein
GCD73_RS18925	COG2879	small protein
GCD73_RS18945	COG0783	Belongs to the Dps family
GCD73_RS18950	COG0384	phenazine biosynthesis protein PhzF
GCD73_RS18970	COG0583	DNA-binding transcription factor activity
GCD73_RS18980	COG0154	amidase activity
GCD73_RS18990	COG0251	oxidation-reduction process
GCD73_RS18995	COG0583	DNA-binding transcription factor activity
GCD73_RS19000	COG2203	Gaf domain
GCD73_RS19000	COG2199	diguanylate cyclase activity
GCD73_RS19010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GCD73_RS19015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GCD73_RS19025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GCD73_RS19030	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GCD73_RS19035	COG0745	RESPONSE REGULATOR receiver
GCD73_RS19040	COG5002	protein histidine kinase activity
GCD73_RS19045	COG0574	Belongs to the PEP-utilizing enzyme family
GCD73_RS19045	COG3848	Pyruvate phosphate dikinase
GCD73_RS19055	COG0697	spore germination
GCD73_RS19065	COG4941	Belongs to the sigma-70 factor family
GCD73_RS19075	COG3795	YCII-related domain
GCD73_RS19080	COG3795	YCII-related domain
GCD73_RS19095	COG3047	cAMP biosynthetic process
GCD73_RS19095	COG2885	chlorophyll binding
GCD73_RS19115	COG1683	Conserved Protein
GCD73_RS19130	COG1309	transcriptional regulator
GCD73_RS19135	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS19140	COG0668	transmembrane transport
GCD73_RS19180	COG4608	Belongs to the ABC transporter superfamily
GCD73_RS19185	COG0444	Belongs to the ABC transporter superfamily
GCD73_RS19190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS19195	COG0601	transmembrane transport
GCD73_RS19205	COG1802	Transcriptional regulator
GCD73_RS19210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCD73_RS19220	COG0667	Aldo Keto reductase
GCD73_RS19230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCD73_RS19235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCD73_RS19255	COG1414	Transcriptional regulator
GCD73_RS19260	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GCD73_RS19285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCD73_RS19290	COG0436	Aminotransferase
GCD73_RS19295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS19300	COG0765	amino acid transport
GCD73_RS19305	COG0765	amino acid transport
GCD73_RS19310	COG1126	abc transporter atp-binding protein
GCD73_RS19325	COG0587	DNA-directed DNA polymerase activity
GCD73_RS19340	COG0400	carboxylic ester hydrolase activity
GCD73_RS19350	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS19360	COG0028	Belongs to the TPP enzyme family
GCD73_RS19375	COG1566	PFAM secretion protein HlyD family protein
GCD73_RS19395	COG0720	synthase
GCD73_RS19400	COG0602	queuosine metabolic process
GCD73_RS19420	COG1902	pentaerythritol trinitrate reductase activity
GCD73_RS19465	COG0842	Transport permease protein
GCD73_RS19470	COG1131	(ABC) transporter
GCD73_RS19480	COG1309	transcriptional regulator
GCD73_RS19485	COG2130	NADP-dependent
GCD73_RS19490	COG0693	protein deglycase activity
GCD73_RS19510	COG3842	ATPase activity
GCD73_RS19515	COG3842	ATPase activity
GCD73_RS19525	COG0395	ABC-type sugar transport system, permease component
GCD73_RS19545	COG2199	diguanylate cyclase activity
GCD73_RS19545	COG2203	Gaf domain
GCD73_RS19550	COG3634	alkyl hydroperoxide reductase activity
GCD73_RS19560	COG3387	PFAM Glycoside hydrolase 15-related
GCD73_RS19565	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS19600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCD73_RS19605	COG0420	3'-5' exonuclease activity
GCD73_RS19630	COG2111	Na H antiporter
GCD73_RS19630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GCD73_RS19635	COG1006	Multisubunit Na H antiporter MnhC subunit
GCD73_RS19640	COG0651	ATP synthesis coupled electron transport
GCD73_RS19645	COG1863	multisubunit Na H antiporter MnhE subunit
GCD73_RS19650	COG2212	antiporter activity
GCD73_RS19655	COG1320	monovalent cation:proton antiporter activity
GCD73_RS19670	COG0590	tRNA wobble adenosine to inosine editing
GCD73_RS19675	COG1619	proteins homologs of microcin C7 resistance protein MccF
GCD73_RS19680	COG0488	(ABC) transporter
GCD73_RS19715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCD73_RS19720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCD73_RS19730	COG2252	PERMEase
GCD73_RS19735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GCD73_RS19740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GCD73_RS19750	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GCD73_RS19775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCD73_RS19780	COG0789	Transcriptional regulator
GCD73_RS19795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCD73_RS19795	COG0678	peroxiredoxin activity
GCD73_RS19805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GCD73_RS19810	COG0584	glycerophosphoryl diester phosphodiesterase
GCD73_RS19820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCD73_RS19830	COG4181	ATPase activity
GCD73_RS19845	COG0583	DNA-binding transcription factor activity
GCD73_RS19860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GCD73_RS19875	COG4336	lyase activity
GCD73_RS19885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCD73_RS19925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS19930	COG0765	amino acid transport
GCD73_RS19935	COG1126	abc transporter atp-binding protein
GCD73_RS19940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCD73_RS19945	COG1758	RNA polymerase activity
GCD73_RS19950	COG0194	GDP metabolic process
GCD73_RS19955	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS19960	COG0791	NLP P60 protein
GCD73_RS19965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCD73_RS19970	COG0833	amino acid
GCD73_RS19975	COG1561	YicC-like family, N-terminal region
GCD73_RS19980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GCD73_RS19990	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS20000	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GCD73_RS20005	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GCD73_RS20010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCD73_RS20015	COG0174	glutamine synthetase
GCD73_RS20025	COG2204	response regulator
GCD73_RS20030	COG0583	DNA-binding transcription factor activity
GCD73_RS20035	COG1741	Belongs to the pirin family
GCD73_RS20040	COG1741	Belongs to the pirin family
GCD73_RS20060	COG3842	ATPase activity
GCD73_RS20065	COG1178	ABC-type Fe3 transport system permease component
GCD73_RS20070	COG1840	ABC-type Fe3 transport system, periplasmic component
GCD73_RS20105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCD73_RS20110	COG0583	DNA-binding transcription factor activity
GCD73_RS20115	COG0783	Belongs to the Dps family
GCD73_RS20130	COG3842	ATPase activity
GCD73_RS20135	COG0395	ABC-type sugar transport system, permease component
GCD73_RS20140	COG1175	transmembrane transport
GCD73_RS20145	COG1653	transport
GCD73_RS20150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GCD73_RS20180	COG1794	racemase activity, acting on amino acids and derivatives
GCD73_RS20185	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GCD73_RS20195	COG0583	DNA-binding transcription factor activity
GCD73_RS20200	COG0625	glutathione transferase activity
GCD73_RS20205	COG2133	pyrroloquinoline quinone binding
GCD73_RS20215	COG0697	spore germination
GCD73_RS20220	COG2363	Small membrane protein
GCD73_RS20245	COG1414	Transcriptional regulator
GCD73_RS20250	COG0010	Belongs to the arginase family
GCD73_RS20255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GCD73_RS20260	COG1464	Belongs to the NlpA lipoprotein family
GCD73_RS20270	COG1408	metallophosphoesterase
GCD73_RS20280	COG0688	phosphatidylethanolamine metabolic process
GCD73_RS20285	COG0488	(ABC) transporter
GCD73_RS20305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCD73_RS20310	COG2203	Gaf domain
GCD73_RS20310	COG2199	diguanylate cyclase activity
GCD73_RS20310	COG2200	EAL domain
GCD73_RS20330	COG2814	Major facilitator Superfamily
GCD73_RS20335	COG0784	Response regulator, receiver
GCD73_RS20335	COG4191	Histidine kinase
GCD73_RS20345	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GCD73_RS20350	COG2204	response regulator
GCD73_RS20355	COG2204	response regulator
GCD73_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS20420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCD73_RS20430	COG1289	transmembrane transporter activity
GCD73_RS20435	COG2200	EAL domain
GCD73_RS20435	COG2199	diguanylate cyclase activity
GCD73_RS20450	COG1640	4-alpha-glucanotransferase
GCD73_RS20455	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GCD73_RS20465	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GCD73_RS20470	COG0366	Alpha amylase catalytic
GCD73_RS20475	COG0366	Alpha amylase catalytic
GCD73_RS20480	COG0297	glycogen (starch) synthase activity
GCD73_RS20485	COG0028	Belongs to the TPP enzyme family
GCD73_RS20530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCD73_RS20535	COG3568	Endonuclease Exonuclease Phosphatase
GCD73_RS20540	COG0659	secondary active sulfate transmembrane transporter activity
GCD73_RS20545	COG2863	cytochrome
GCD73_RS20565	COG1253	flavin adenine dinucleotide binding
GCD73_RS20575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GCD73_RS20600	COG1024	Enoyl-CoA hydratase
GCD73_RS20635	COG2199	diguanylate cyclase activity
GCD73_RS20650	COG0028	Belongs to the TPP enzyme family
GCD73_RS20660	COG2197	response regulator
GCD73_RS20665	COG2205	protein histidine kinase activity
GCD73_RS20665	COG0784	Response regulator, receiver
GCD73_RS20670	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GCD73_RS20675	COG0784	Response regulator, receiver
GCD73_RS20675	COG2205	protein histidine kinase activity
GCD73_RS20690	COG0628	permease
GCD73_RS20695	COG1187	pseudouridine synthase activity
GCD73_RS20715	COG1959	2 iron, 2 sulfur cluster binding
GCD73_RS20725	COG0531	amino acid
GCD73_RS20745	COG3119	arylsulfatase activity
GCD73_RS20760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GCD73_RS20770	COG3243	poly(R)-hydroxyalkanoic acid synthase
GCD73_RS20780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCD73_RS20785	COG2197	response regulator
GCD73_RS20805	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GCD73_RS20810	COG0589	response to stress
GCD73_RS20820	COG0589	response to stress
GCD73_RS20835	COG0589	response to stress
GCD73_RS20850	COG0431	NADPH-dependent FMN reductase
GCD73_RS20860	COG0798	PFAM Bile acid sodium symporter
GCD73_RS20880	COG4993	Dehydrogenase
GCD73_RS20885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GCD73_RS20920	COG0288	reversible hydration of carbon dioxide
GCD73_RS20925	COG2226	methyltransferase
GCD73_RS20940	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GCD73_RS20950	COG3038	cytochrome b561
GCD73_RS21040	COG1121	(ABC) transporter
GCD73_RS21045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCD73_RS21065	COG2721	sulfolactate sulfo-lyase activity
GCD73_RS21105	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS21110	COG3386	PFAM SMP-30 Gluconolaconase
GCD73_RS21115	COG2721	sulfolactate sulfo-lyase activity
GCD73_RS21120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCD73_RS21140	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS21145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCD73_RS21155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS21160	COG0436	Aminotransferase
GCD73_RS21165	COG4597	amino acid ABC transporter
GCD73_RS21170	COG0765	amino acid transport
GCD73_RS21175	COG1126	abc transporter atp-binding protein
GCD73_RS21180	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCD73_RS21195	COG0745	RESPONSE REGULATOR receiver
GCD73_RS21205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCD73_RS21210	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GCD73_RS21215	COG1120	ATPase activity
GCD73_RS21225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCD73_RS21235	COG0390	transport system, permease component
GCD73_RS21240	COG0577	efflux transmembrane transporter activity
GCD73_RS21240	COG1136	(ABC) transporter
GCD73_RS21255	COG1126	abc transporter atp-binding protein
GCD73_RS21260	COG0765	amino acid transport
GCD73_RS21265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS21295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCD73_RS21315	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS21320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GCD73_RS21325	COG0583	DNA-binding transcription factor activity
GCD73_RS21350	COG4566	intracellular signal transduction
GCD73_RS21365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GCD73_RS21365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCD73_RS21375	COG0783	Belongs to the Dps family
GCD73_RS21380	COG4191	Histidine kinase
GCD73_RS21385	COG4566	intracellular signal transduction
GCD73_RS21450	COG1335	isochorismatase
GCD73_RS21465	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS21535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCD73_RS21545	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS21560	COG3706	GGDEF domain
GCD73_RS21570	COG0384	phenazine biosynthesis protein PhzF
GCD73_RS21585	COG0251	oxidation-reduction process
GCD73_RS21610	COG0693	protein deglycase activity
GCD73_RS21635	COG4774	siderophore transport
GCD73_RS21665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GCD73_RS21665	COG2010	Cytochrome c
GCD73_RS21670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCD73_RS21685	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCD73_RS21695	COG2226	methyltransferase
GCD73_RS21705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCD73_RS21735	COG1104	cysteine desulfurase activity
GCD73_RS21740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS21745	COG4597	amino acid ABC transporter
GCD73_RS21750	COG3154	lipid carrier protein
GCD73_RS21755	COG0826	peptidase U32
GCD73_RS21760	COG0826	peptidase U32
GCD73_RS21765	COG2197	response regulator
GCD73_RS21775	COG1763	Mo-molybdopterin cofactor biosynthetic process
GCD73_RS21780	COG0288	reversible hydration of carbon dioxide
GCD73_RS21785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GCD73_RS21790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCD73_RS21795	COG2181	nitrate reductase activity
GCD73_RS21800	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GCD73_RS21805	COG1140	nitrate reductase beta subunit
GCD73_RS21810	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GCD73_RS21815	COG2223	nitrite transmembrane transporter activity
GCD73_RS21850	COG1538	Outer membrane efflux protein
GCD73_RS21855	COG1566	PFAM secretion protein HlyD family protein
GCD73_RS21870	COG0583	DNA-binding transcription factor activity
GCD73_RS21905	COG1328	CTP reductase activity
GCD73_RS21920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCD73_RS21940	COG2070	2-Nitropropane dioxygenase
GCD73_RS21945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCD73_RS21970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GCD73_RS21980	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GCD73_RS21985	COG0154	amidase activity
GCD73_RS21990	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS21995	COG3048	D-serine ammonia-lyase activity
GCD73_RS22005	COG4773	Receptor
GCD73_RS22035	COG2885	chlorophyll binding
GCD73_RS22055	COG2211	Major facilitator Superfamily
GCD73_RS22070	COG0438	transferase activity, transferring glycosyl groups
GCD73_RS22080	COG2205	protein histidine kinase activity
GCD73_RS22085	COG0745	RESPONSE REGULATOR receiver
GCD73_RS22095	COG2032	superoxide dismutase activity
GCD73_RS22100	COG2733	membrane
GCD73_RS22105	COG0628	permease
GCD73_RS22110	COG0583	DNA-binding transcription factor activity
GCD73_RS22115	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCD73_RS22115	COG1024	Enoyl-CoA hydratase
GCD73_RS22120	COG0183	Belongs to the thiolase family
GCD73_RS22125	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS22130	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS22135	COG0318	PFAM AMP-dependent synthetase and ligase
GCD73_RS22155	COG0477	Major facilitator Superfamily
GCD73_RS22170	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS22175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCD73_RS22180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCD73_RS22185	COG1802	Transcriptional regulator
GCD73_RS22190	COG2203	Gaf domain
GCD73_RS22190	COG3706	GGDEF domain
GCD73_RS22190	COG5001	Diguanylate cyclase
GCD73_RS22190	COG4251	negative regulation of phosphorylation
GCD73_RS22195	COG2201	protein-glutamate methylesterase activity
GCD73_RS22220	COG0840	transmembrane signaling receptor activity
GCD73_RS22260	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GCD73_RS22280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GCD73_RS22280	COG0519	Catalyzes the synthesis of GMP from XMP
GCD73_RS22320	COG0583	DNA-binding transcription factor activity
GCD73_RS22330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCD73_RS22365	COG2072	flavoprotein involved in K transport
GCD73_RS22370	COG0601	transmembrane transport
GCD73_RS22375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS22380	COG0444	Belongs to the ABC transporter superfamily
GCD73_RS22385	COG4608	Belongs to the ABC transporter superfamily
GCD73_RS22390	COG0747	negative chemotaxis
GCD73_RS22415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GCD73_RS22425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCD73_RS22430	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS22445	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCD73_RS22450	COG3971	2-oxopent-4-enoate hydratase activity
GCD73_RS22485	COG2130	NADP-dependent
GCD73_RS22490	COG0583	DNA-binding transcription factor activity
GCD73_RS22550	COG2353	YceI-like domain
GCD73_RS22575	COG0583	DNA-binding transcription factor activity
GCD73_RS22595	COG0047	phosphoribosylformylglycinamidine synthase activity
GCD73_RS22595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GCD73_RS22605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GCD73_RS22605	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GCD73_RS22610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCD73_RS22620	COG0613	PHP domain protein
GCD73_RS22630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCD73_RS22640	COG0583	DNA-binding transcription factor activity
GCD73_RS22645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCD73_RS22645	COG2146	nitrite reductase [NAD(P)H] activity
GCD73_RS22655	COG2116	formate transmembrane transporter activity
GCD73_RS22660	COG0515	serine threonine protein kinase
GCD73_RS22670	COG3707	response regulator
GCD73_RS22680	COG1566	PFAM secretion protein HlyD family protein
GCD73_RS22710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCD73_RS22715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GCD73_RS22725	COG1850	ribulose-bisphosphate carboxylase activity
GCD73_RS22740	COG4221	oxidoreductase activity
GCD73_RS22755	COG4977	sequence-specific DNA binding
GCD73_RS22755	COG1917	Cupin 2, conserved barrel domain protein
GCD73_RS22765	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS22780	COG3179	chitinase
GCD73_RS22795	COG0737	Belongs to the 5'-nucleotidase family
GCD73_RS22800	COG4604	ABC transporter, ATP-binding protein
GCD73_RS22805	COG4605	iron ion homeostasis
GCD73_RS22810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCD73_RS22815	COG4607	ABC-type enterochelin transport system periplasmic component
GCD73_RS22820	COG4771	TonB-dependent receptor
GCD73_RS22825	COG0745	RESPONSE REGULATOR receiver
GCD73_RS22835	COG0084	hydrolase, TatD family'
GCD73_RS22840	COG1136	(ABC) transporter
GCD73_RS22860	COG2271	Major facilitator Superfamily
GCD73_RS22870	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS22875	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GCD73_RS22890	COG0183	Belongs to the thiolase family
GCD73_RS22895	COG1022	Amp-dependent synthetase and ligase
GCD73_RS22910	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCD73_RS22935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS22945	COG0583	DNA-binding transcription factor activity
GCD73_RS22950	COG1803	Methylglyoxal synthase
GCD73_RS22965	COG0443	Heat shock 70 kDa protein
GCD73_RS22970	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GCD73_RS22980	COG0822	iron-sulfur transferase activity
GCD73_RS22985	COG1104	cysteine desulfurase activity
GCD73_RS22995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GCD73_RS23000	COG0556	nucleotide-excision repair
GCD73_RS23010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GCD73_RS23015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GCD73_RS23020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GCD73_RS23025	COG0740	serine-type endopeptidase activity
GCD73_RS23030	COG0544	peptidyl-prolyl cis-trans isomerase activity
GCD73_RS23035	COG0501	Belongs to the peptidase M48B family
GCD73_RS23045	COG1278	Cold shock
GCD73_RS23060	COG1278	Cold shock
GCD73_RS23085	COG0251	oxidation-reduction process
GCD73_RS23115	COG3008	intermembrane lipid transfer
GCD73_RS23120	COG0456	acetyltransferase
GCD73_RS23130	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GCD73_RS23145	COG2200	EAL domain
GCD73_RS23160	COG2171	N-acyltransferase activity
GCD73_RS23165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GCD73_RS23170	COG2890	protein-(glutamine-N5) methyltransferase activity
GCD73_RS23175	COG0488	(ABC) transporter
GCD73_RS23185	COG0210	DNA helicase
GCD73_RS23200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GCD73_RS23200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GCD73_RS23205	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GCD73_RS23210	COG0196	riboflavin kinase activity
GCD73_RS23215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GCD73_RS23220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GCD73_RS23225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GCD73_RS23295	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GCD73_RS23300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GCD73_RS23305	COG1902	pentaerythritol trinitrate reductase activity
GCD73_RS23310	COG1126	abc transporter atp-binding protein
GCD73_RS23315	COG0765	amino acid transport
GCD73_RS23320	COG0765	amino acid transport
GCD73_RS23325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS23335	COG1764	response to oxidative stress
GCD73_RS23340	COG1914	H( )-stimulated, divalent metal cation uptake system
GCD73_RS23355	COG2271	Major facilitator Superfamily
GCD73_RS23360	COG1802	Transcriptional regulator
GCD73_RS23370	COG1024	Enoyl-CoA hydratase
GCD73_RS23375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS23395	COG0559	Belongs to the binding-protein-dependent transport system permease family
GCD73_RS23405	COG0506	proline dehydrogenase activity
GCD73_RS23405	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCD73_RS23405	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCD73_RS23415	COG3008	intermembrane lipid transfer
GCD73_RS23420	COG2995	paraquat-inducible protein a
GCD73_RS23425	COG0542	response to heat
GCD73_RS23430	COG4953	penicillin-binding protein 1C
GCD73_RS23440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GCD73_RS23445	COG1278	Cold shock
GCD73_RS23455	COG0183	Belongs to the thiolase family
GCD73_RS23460	COG0038	chloride channel
GCD73_RS23470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GCD73_RS23480	COG1570	exodeoxyribonuclease VII activity
GCD73_RS23485	COG0811	peptide transport
GCD73_RS23500	COG2835	tetraacyldisaccharide 4'-kinase activity
GCD73_RS23505	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GCD73_RS23510	COG0563	adenylate kinase activity
GCD73_RS23520	COG0728	peptidoglycan biosynthetic process
GCD73_RS23530	COG0268	Binds directly to 16S ribosomal RNA
GCD73_RS23535	COG0583	DNA-binding transcription factor activity
GCD73_RS23555	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GCD73_RS23560	COG2186	Transcriptional regulator
GCD73_RS23570	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS23575	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS23580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCD73_RS23620	COG4774	siderophore transport
GCD73_RS23625	COG3712	iron ion homeostasis
GCD73_RS23630	COG1595	DNA-templated transcription, initiation
GCD73_RS23635	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS23640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCD73_RS23645	COG1562	ergosterol biosynthetic process
GCD73_RS23650	COG1562	ergosterol biosynthetic process
GCD73_RS23660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCD73_RS23685	COG0583	DNA-binding transcription factor activity
GCD73_RS23695	COG2188	Transcriptional regulator
GCD73_RS23700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCD73_RS23725	COG1477	protein flavinylation
GCD73_RS23730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GCD73_RS23740	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GCD73_RS23745	COG0583	DNA-binding transcription factor activity
GCD73_RS23755	COG5564	TIM-barrel signal transduction protein
GCD73_RS23760	COG5441	Belongs to the UPF0261 family
GCD73_RS23780	COG0542	response to heat
GCD73_RS23790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCD73_RS23825	COG0494	nUDIX hydrolase
GCD73_RS23830	COG0443	Heat shock 70 kDa protein
GCD73_RS23840	COG3530	Putative quorum-sensing-regulated virulence factor
GCD73_RS23905	COG1522	sequence-specific DNA binding
GCD73_RS23915	COG3328	transposase activity
GCD73_RS23975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS23985	COG0456	acetyltransferase
GCD73_RS24000	COG2951	lytic endotransglycosylase activity
GCD73_RS24015	COG0583	DNA-binding transcription factor activity
GCD73_RS24030	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS24035	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GCD73_RS24055	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS24065	COG0023	Translation Initiation Factor
GCD73_RS24095	COG2011	ABC-type metal ion transport system permease component
GCD73_RS24100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GCD73_RS24105	COG1464	Belongs to the NlpA lipoprotein family
GCD73_RS24125	COG1228	amidohydrolase
GCD73_RS24130	COG0596	Alpha beta hydrolase
GCD73_RS24135	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCD73_RS24160	COG0840	transmembrane signaling receptor activity
GCD73_RS24170	COG2169	Transcriptional regulator
GCD73_RS24195	COG1272	protein, Hemolysin III
GCD73_RS24215	COG0842	Transport permease protein
GCD73_RS24220	COG1131	(ABC) transporter
GCD73_RS24235	COG0348	domain, Protein
GCD73_RS24255	COG3278	Belongs to the heme-copper respiratory oxidase family
GCD73_RS24270	COG4106	trans-aconitate 2-methyltransferase activity
GCD73_RS24270	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCD73_RS24275	COG0583	DNA-binding transcription factor activity
GCD73_RS24280	COG1064	alcohol dehydrogenase
GCD73_RS24290	COG2224	Isocitrate lyase
GCD73_RS24295	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GCD73_RS24295	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GCD73_RS24300	COG1858	cytochrome C peroxidase
GCD73_RS24310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GCD73_RS24325	COG0736	holo-[acyl-carrier-protein] synthase activity
GCD73_RS24330	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GCD73_RS24340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCD73_RS24345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCD73_RS24370	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GCD73_RS24375	COG4149	molybdate abc transporter
GCD73_RS24385	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GCD73_RS24405	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GCD73_RS24410	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GCD73_RS24410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCD73_RS24415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCD73_RS24425	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GCD73_RS24430	COG4120	Belongs to the binding-protein-dependent transport system permease family
GCD73_RS24440	COG0667	Aldo Keto reductase
GCD73_RS24450	COG0318	PFAM AMP-dependent synthetase and ligase
GCD73_RS24455	COG1024	Enoyl-CoA hydratase
GCD73_RS24465	COG1802	Transcriptional regulator
GCD73_RS24485	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS24490	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS24505	COG1024	Enoyl-CoA hydratase
GCD73_RS24515	COG0183	Belongs to the thiolase family
GCD73_RS24520	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS24530	COG0517	IMP dehydrogenase activity
GCD73_RS24580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GCD73_RS24585	COG3384	dioxygenase
GCD73_RS24600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GCD73_RS24610	COG4172	Belongs to the ABC transporter superfamily
GCD73_RS24615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCD73_RS24620	COG0601	transmembrane transport
GCD73_RS24635	COG0598	Magnesium transport protein CorA
GCD73_RS24655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCD73_RS24660	COG1012	belongs to the aldehyde dehydrogenase family
GCD73_RS24670	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GCD73_RS24675	COG1045	serine acetyltransferase
GCD73_RS24680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GCD73_RS24685	COG0166	Belongs to the GPI family
GCD73_RS24700	COG1596	polysaccharide export
GCD73_RS24730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCD73_RS24750	COG0438	transferase activity, transferring glycosyl groups
GCD73_RS24760	COG0110	maltose O-acetyltransferase activity
GCD73_RS24765	COG0297	glycogen (starch) synthase activity
GCD73_RS24795	COG2197	response regulator
GCD73_RS24800	COG2197	response regulator
GCD73_RS24820	COG0183	Belongs to the thiolase family
GCD73_RS24835	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCD73_RS24835	COG1024	Enoyl-CoA hydratase
GCD73_RS24840	COG0183	Belongs to the thiolase family
GCD73_RS24870	COG3395	kinase activity
GCD73_RS24875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GCD73_RS24890	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS24895	COG1609	Transcriptional regulator
GCD73_RS24900	COG1595	DNA-templated transcription, initiation
GCD73_RS24915	COG1764	response to oxidative stress
GCD73_RS24935	COG2186	Transcriptional regulator
GCD73_RS24940	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCD73_RS24950	COG0318	PFAM AMP-dependent synthetase and ligase
GCD73_RS24955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GCD73_RS24965	COG1024	Enoyl-CoA hydratase
GCD73_RS24975	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS24985	COG1414	Transcriptional regulator
GCD73_RS24995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GCD73_RS25010	COG0583	DNA-binding transcription factor activity
GCD73_RS25040	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GCD73_RS25060	COG0825	malonyl-CoA metabolic process
GCD73_RS25070	COG0215	cysteine-tRNA ligase activity
GCD73_RS25085	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GCD73_RS25090	COG1968	undecaprenyl-diphosphatase activity
GCD73_RS25095	COG1253	flavin adenine dinucleotide binding
GCD73_RS25110	COG4263	nitrous-oxide reductase activity
GCD73_RS25125	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GCD73_RS25140	COG0483	inositol monophosphate 1-phosphatase activity
GCD73_RS25160	COG0668	transmembrane transport
GCD73_RS25190	COG0235	Class ii aldolase
GCD73_RS25210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCD73_RS25215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCD73_RS25235	COG1802	Transcriptional regulator
GCD73_RS25255	COG3360	Dodecin
GCD73_RS25265	COG0583	DNA-binding transcription factor activity
GCD73_RS25270	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS25290	COG3339	Conserved Protein
GCD73_RS25295	COG1278	Cold shock
GCD73_RS25305	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GCD73_RS25310	COG2850	peptidyl-arginine hydroxylation
GCD73_RS25320	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GCD73_RS25325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCD73_RS25330	COG1994	Peptidase M50
GCD73_RS25335	COG0009	L-threonylcarbamoyladenylate synthase
GCD73_RS25340	COG2321	neutral zinc metallopeptidase
GCD73_RS25390	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GCD73_RS25400	COG0490	domain, Protein
GCD73_RS25400	COG0471	metal ion transport
GCD73_RS25435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCD73_RS25440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCD73_RS25450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GCD73_RS25455	COG0784	Response regulator, receiver
GCD73_RS25455	COG4191	Histidine kinase
GCD73_RS25460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCD73_RS25490	COG3685	Protein conserved in bacteria
GCD73_RS25520	COG0668	transmembrane transport
GCD73_RS25530	COG0387	Pfam Sodium calcium exchanger
GCD73_RS25555	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GCD73_RS25570	COG0668	transmembrane transport
GCD73_RS25600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCD73_RS25610	COG2084	Dehydrogenase
GCD73_RS25620	COG1802	Transcriptional regulator
GCD73_RS25635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCD73_RS25655	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCD73_RS25660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GCD73_RS25660	COG0519	Catalyzes the synthesis of GMP from XMP
GCD73_RS25675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCD73_RS25680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCD73_RS25700	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GCD73_RS25730	COG1228	amidohydrolase
GCD73_RS25735	COG2070	2-Nitropropane dioxygenase
GCD73_RS25745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS25750	COG1024	Enoyl-CoA hydratase
GCD73_RS25760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCD73_RS25785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GCD73_RS25790	COG0765	amino acid transport
GCD73_RS25800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS25805	COG1126	abc transporter atp-binding protein
GCD73_RS25810	COG1012	belongs to the aldehyde dehydrogenase family
GCD73_RS25825	COG2197	response regulator
GCD73_RS25830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCD73_RS25835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCD73_RS25840	COG1116	anion transmembrane transporter activity
GCD73_RS25845	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GCD73_RS25860	COG1396	sequence-specific DNA binding
GCD73_RS25875	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS25890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCD73_RS25890	COG0473	3-isopropylmalate dehydrogenase activity
GCD73_RS25895	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS25910	COG0793	Belongs to the peptidase S41A family
GCD73_RS25925	COG0583	DNA-binding transcription factor activity
GCD73_RS25930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCD73_RS25950	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS25955	COG1024	Enoyl-CoA hydratase
GCD73_RS25960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS25965	COG0583	DNA-binding transcription factor activity
GCD73_RS25975	COG1126	abc transporter atp-binding protein
GCD73_RS25980	COG0765	amino acid transport
GCD73_RS25990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS26000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCD73_RS26010	COG1063	alcohol dehydrogenase
GCD73_RS26035	COG0071	Belongs to the small heat shock protein (HSP20) family
GCD73_RS26070	COG1024	Enoyl-CoA hydratase
GCD73_RS26080	COG1595	DNA-templated transcription, initiation
GCD73_RS26120	COG1058	Belongs to the CinA family
GCD73_RS26120	COG1546	Belongs to the CinA family
GCD73_RS26130	COG0500	methyltransferase
GCD73_RS26145	COG1201	RNA secondary structure unwinding
GCD73_RS26150	COG1793	dna ligase
GCD73_RS26155	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GCD73_RS26155	COG1793	dna ligase
GCD73_RS26175	COG1063	alcohol dehydrogenase
GCD73_RS26195	COG1408	metallophosphoesterase
GCD73_RS26210	COG0583	DNA-binding transcription factor activity
GCD73_RS26235	COG3448	diguanylate cyclase activity
GCD73_RS26235	COG4175	Glycine betaine
GCD73_RS26240	COG4176	ABC-type proline glycine betaine transport system permease component
GCD73_RS26250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCD73_RS26255	COG2814	Major facilitator Superfamily
GCD73_RS26260	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GCD73_RS26265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GCD73_RS26295	COG1686	Belongs to the peptidase S11 family
GCD73_RS26305	COG1846	Transcriptional regulator
GCD73_RS26310	COG2814	Major facilitator Superfamily
GCD73_RS26315	COG0495	leucyl-tRNA aminoacylation
GCD73_RS26330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GCD73_RS26345	COG0154	amidase activity
GCD73_RS26355	COG0477	Major facilitator Superfamily
GCD73_RS26365	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCD73_RS26380	COG0583	DNA-binding transcription factor activity
GCD73_RS26415	COG0583	DNA-binding transcription factor activity
GCD73_RS26420	COG0427	acetyl-CoA hydrolase
GCD73_RS26425	COG0583	DNA-binding transcription factor activity
GCD73_RS26430	COG3264	Mechanosensitive ion channel
GCD73_RS26430	COG1511	domain protein
GCD73_RS26485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GCD73_RS26490	COG3958	Transketolase
GCD73_RS26495	COG3959	Transketolase, thiamine diphosphate binding domain
GCD73_RS26500	COG1802	Transcriptional regulator
GCD73_RS26505	COG0371	Dehydrogenase
GCD73_RS26515	COG1250	3-hydroxyacyl-CoA dehydrogenase
GCD73_RS26520	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS26530	COG0559	Belongs to the binding-protein-dependent transport system permease family
GCD73_RS26545	COG4221	oxidoreductase activity
GCD73_RS26545	COG0604	alcohol dehydrogenase
GCD73_RS26545	COG3321	synthase
GCD73_RS26545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCD73_RS26550	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS26555	COG0500	methyltransferase
GCD73_RS26580	COG0667	Aldo Keto reductase
GCD73_RS26585	COG2207	Transcriptional regulator
GCD73_RS26590	COG0583	DNA-binding transcription factor activity
GCD73_RS26595	COG1335	isochorismatase
GCD73_RS26615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS26620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GCD73_RS26625	COG0583	DNA-binding transcription factor activity
GCD73_RS26690	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS26695	COG0582	viral genome integration into host DNA
GCD73_RS26840	COG1674	ftsk spoiiie
GCD73_RS26850	COG0730	response to heat
GCD73_RS26860	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS26865	COG0583	DNA-binding transcription factor activity
GCD73_RS26875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GCD73_RS26880	COG0463	Glycosyl transferase, family 2
GCD73_RS26915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCD73_RS26935	COG2217	Heavy metal translocating P-type atpase
GCD73_RS26945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCD73_RS26955	COG2847	Copper chaperone PCu(A)C
GCD73_RS26965	COG0789	Transcriptional regulator
GCD73_RS26970	COG3093	addiction module antidote protein HigA
GCD73_RS26980	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GCD73_RS27000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GCD73_RS27120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GCD73_RS27140	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GCD73_RS27165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GCD73_RS27170	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GCD73_RS27175	COG1534	Rna-binding protein
GCD73_RS27180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCD73_RS27185	COG2233	PERMEase
GCD73_RS27205	COG3842	ATPase activity
GCD73_RS27215	COG0406	alpha-ribazole phosphatase activity
GCD73_RS27225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GCD73_RS27230	COG0505	Belongs to the CarA family
GCD73_RS27235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GCD73_RS27250	COG0745	RESPONSE REGULATOR receiver
GCD73_RS27265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCD73_RS27275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCD73_RS27280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS27295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GCD73_RS27305	COG1074	ATP-dependent DNA helicase activity
GCD73_RS27330	COG1686	Belongs to the peptidase S11 family
GCD73_RS27355	COG4974	Belongs to the 'phage' integrase family
GCD73_RS27360	COG0583	DNA-binding transcription factor activity
GCD73_RS27365	COG0028	Belongs to the TPP enzyme family
GCD73_RS27370	COG1960	acyl-CoA dehydrogenase activity
GCD73_RS27400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GCD73_RS27445	COG0028	Belongs to the TPP enzyme family
GCD73_RS27450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCD73_RS27465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GCD73_RS27470	COG1414	Transcriptional regulator
GCD73_RS27475	COG0009	L-threonylcarbamoyladenylate synthase
GCD73_RS27480	COG4191	Histidine kinase
GCD73_RS27480	COG0784	Response regulator, receiver
GCD73_RS27695	COG1902	pentaerythritol trinitrate reductase activity
GCD73_RS27725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GCD73_RS27725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCD73_RS27735	COG0604	alcohol dehydrogenase
GCD73_RS27735	COG3321	synthase
GCD73_RS27735	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS27740	COG4221	oxidoreductase activity
GCD73_RS27745	COG0583	DNA-binding transcription factor activity
GCD73_RS27760	COG3436	PFAM IS66 Orf2 family protein
GCD73_RS27785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GCD73_RS27795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GCD73_RS27805	COG3181	Tripartite tricarboxylate transporter family receptor
GCD73_RS27810	COG1024	Enoyl-CoA hydratase
GCD73_RS27815	COG1024	Enoyl-CoA hydratase
GCD73_RS27830	COG1902	pentaerythritol trinitrate reductase activity
GCD73_RS27840	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS27870	COG2084	Dehydrogenase
GCD73_RS27880	COG0583	DNA-binding transcription factor activity
GCD73_RS27900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCD73_RS27905	COG1902	pentaerythritol trinitrate reductase activity
GCD73_RS27910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCD73_RS27915	COG0583	DNA-binding transcription factor activity
GCD73_RS27920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCD73_RS27930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCD73_RS27965	COG1309	transcriptional regulator
GCD73_RS28010	COG1902	pentaerythritol trinitrate reductase activity
GCD73_RS28015	COG3284	Transcriptional regulator
GCD73_RS28025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCD73_RS28055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GCD73_RS28095	COG1609	Transcriptional regulator
GCD73_RS28100	COG1063	alcohol dehydrogenase
GCD73_RS28110	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS28140	COG3436	PFAM IS66 Orf2 family protein
GCD73_RS28225	COG1475	DNA binding
GCD73_RS28230	COG1192	Involved in chromosome partitioning
GCD73_RS28345	COG1733	regulation of RNA biosynthetic process
GCD73_RS28350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCD73_RS28350	COG3321	synthase
GCD73_RS28350	COG0604	alcohol dehydrogenase
GCD73_RS28350	COG4221	oxidoreductase activity
GCD73_RS28355	COG3321	synthase
GCD73_RS28355	COG1028	Short-chain dehydrogenase reductase Sdr
GCD73_RS28355	COG0604	alcohol dehydrogenase
GCD73_RS28365	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GCD73_RS28410	COG0640	Transcriptional regulator
GCD73_RS28415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCD73_RS28420	COG1902	pentaerythritol trinitrate reductase activity
GCD73_RS28445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCD73_RS28785	COG0154	amidase activity
GCD73_RS28835	COG0745	RESPONSE REGULATOR receiver
GCD73_RS28845	COG0745	RESPONSE REGULATOR receiver