locus-tag	class	description
AL504_RS00025	COG2205	protein histidine kinase activity
AL504_RS00145	COG1136	(ABC) transporter
AL504_RS00150	COG0084	hydrolase, TatD family'
AL504_RS00160	COG0745	RESPONSE REGULATOR receiver
AL504_RS00165	COG4771	TonB-dependent receptor
AL504_RS00170	COG4607	ABC-type enterochelin transport system periplasmic component
AL504_RS00175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS00180	COG4605	iron ion homeostasis
AL504_RS00185	COG4604	ABC transporter, ATP-binding protein
AL504_RS00205	COG1595	DNA-templated transcription, initiation
AL504_RS00235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS00245	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS00260	COG3119	arylsulfatase activity
AL504_RS00280	COG2304	oxidoreductase activity
AL504_RS00300	COG0714	Associated with various cellular activities
AL504_RS00305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL504_RS00335	COG3093	addiction module antidote protein HigA
AL504_RS00345	COG2149	membrane
AL504_RS00380	COG3119	arylsulfatase activity
AL504_RS00390	COG0277	FAD linked oxidase domain protein
AL504_RS00405	COG0159	tryptophan synthase activity
AL504_RS00415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_RS00420	COG0477	Major facilitator Superfamily
AL504_RS00425	COG0583	DNA-binding transcription factor activity
AL504_RS00435	COG0583	DNA-binding transcription factor activity
AL504_RS00445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_RS00465	COG0613	PHP domain protein
AL504_RS00500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS00505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS00505	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL504_RS00515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL504_RS00515	COG0047	phosphoribosylformylglycinamidine synthase activity
AL504_RS00540	COG0642	Histidine kinase
AL504_RS00555	COG0583	DNA-binding transcription factor activity
AL504_RS00570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL504_RS00580	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS00590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS00595	COG0583	DNA-binding transcription factor activity
AL504_RS00600	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS00625	COG0745	RESPONSE REGULATOR receiver
AL504_RS00630	COG2205	protein histidine kinase activity
AL504_RS00630	COG2198	Histidine kinase
AL504_RS00630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS00630	COG0784	Response regulator, receiver
AL504_RS00635	COG0583	DNA-binding transcription factor activity
AL504_RS00670	COG1953	Uracil, thiamine, allantoin
AL504_RS00685	COG0477	Major facilitator Superfamily
AL504_RS00725	COG0583	DNA-binding transcription factor activity
AL504_RS00755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS00760	COG3706	GGDEF domain
AL504_RS00770	COG4774	siderophore transport
AL504_RS00800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS00815	COG3618	amidohydrolase
AL504_RS00820	COG0583	DNA-binding transcription factor activity
AL504_RS00830	COG1960	acyl-CoA dehydrogenase activity
AL504_RS00840	COG1024	Enoyl-CoA hydratase
AL504_RS00870	COG4773	Receptor
AL504_RS00900	COG4774	siderophore transport
AL504_RS00940	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS00945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_RS00950	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS00955	COG0583	DNA-binding transcription factor activity
AL504_RS00970	COG0747	negative chemotaxis
AL504_RS00975	COG4608	Belongs to the ABC transporter superfamily
AL504_RS00985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS00990	COG0601	transmembrane transport
AL504_RS00995	COG2072	flavoprotein involved in K transport
AL504_RS01005	COG1058	Belongs to the CinA family
AL504_RS01005	COG1546	Belongs to the CinA family
AL504_RS01035	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS01040	COG3048	D-serine ammonia-lyase activity
AL504_RS01070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_RS01080	COG0583	DNA-binding transcription factor activity
AL504_RS01100	COG3468	outer membrane autotransporter barrel domain protein
AL504_RS01115	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS01115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL504_RS01130	COG4264	IucA IucC family
AL504_RS01145	COG0583	DNA-binding transcription factor activity
AL504_RS01175	COG0640	Transcriptional regulator
AL504_RS01180	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AL504_RS01190	COG3321	synthase
AL504_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS01190	COG0604	alcohol dehydrogenase
AL504_RS01205	COG1846	Transcriptional regulator
AL504_RS01225	COG2207	Transcriptional regulator
AL504_RS01230	COG4221	oxidoreductase activity
AL504_RS01245	COG2267	carboxylic ester hydrolase activity
AL504_RS01250	COG0300	oxidoreductase activity
AL504_RS01265	COG0402	S-adenosylhomocysteine deaminase activity
AL504_RS01270	COG2814	Major facilitator Superfamily
AL504_RS01295	COG2207	Transcriptional regulator
AL504_RS01340	COG0583	DNA-binding transcription factor activity
AL504_RS01355	COG0165	Argininosuccinate lyase
AL504_RS01365	COG1214	PFAM Peptidase M22, glycoprotease
AL504_RS01365	COG0456	acetyltransferase
AL504_RS01370	COG0583	DNA-binding transcription factor activity
AL504_RS01385	COG2814	Major facilitator Superfamily
AL504_RS01395	COG0667	Aldo Keto reductase
AL504_RS01400	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL504_RS01405	COG1129	ABC transporter
AL504_RS01415	COG1070	Carbohydrate kinase
AL504_RS01420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL504_RS01425	COG2188	Transcriptional regulator
AL504_RS01460	COG0456	acetyltransferase
AL504_RS01475	COG1199	ATP-dependent helicase activity
AL504_RS01505	COG0840	transmembrane signaling receptor activity
AL504_RS01535	COG3706	GGDEF domain
AL504_RS01535	COG2203	Gaf domain
AL504_RS01535	COG5001	Diguanylate cyclase
AL504_RS01535	COG4251	negative regulation of phosphorylation
AL504_RS01540	COG4149	molybdate abc transporter
AL504_RS01545	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_RS01550	COG3842	ATPase activity
AL504_RS01555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS01560	COG1522	sequence-specific DNA binding
AL504_RS01570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL504_RS01580	COG2010	Cytochrome c
AL504_RS01580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL504_RS01585	COG1335	isochorismatase
AL504_RS01590	COG2309	aminopeptidase activity
AL504_RS01595	COG0596	Alpha beta hydrolase
AL504_RS01605	COG2080	2 iron, 2 sulfur cluster binding
AL504_RS01615	COG0477	Major facilitator Superfamily
AL504_RS01620	COG1846	Transcriptional regulator
AL504_RS01625	COG2814	Major facilitator Superfamily
AL504_RS01630	COG4771	TonB-dependent receptor
AL504_RS01645	COG0583	DNA-binding transcription factor activity
AL504_RS01670	COG0583	DNA-binding transcription factor activity
AL504_RS01675	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL504_RS01685	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS01690	COG1960	acyl-CoA dehydrogenase activity
AL504_RS01695	COG1960	acyl-CoA dehydrogenase activity
AL504_RS01700	COG0183	Belongs to the thiolase family
AL504_RS01705	COG1024	Enoyl-CoA hydratase
AL504_RS01705	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS01710	COG0583	DNA-binding transcription factor activity
AL504_RS01745	COG0148	phosphopyruvate hydratase activity
AL504_RS01755	COG2733	membrane
AL504_RS01765	COG0625	glutathione transferase activity
AL504_RS01775	COG0024	Methionine aminopeptidase
AL504_RS01970	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AL504_RS01980	COG2885	chlorophyll binding
AL504_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS02030	COG3971	2-oxopent-4-enoate hydratase activity
AL504_RS02035	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS02055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS02060	COG1414	Transcriptional regulator
AL504_RS02070	COG3541	Predicted nucleotidyltransferase
AL504_RS02075	COG1846	Transcriptional regulator
AL504_RS02105	COG0456	acetyltransferase
AL504_RS02115	COG0583	DNA-binding transcription factor activity
AL504_RS02125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL504_RS02135	COG0697	spore germination
AL504_RS02140	COG2207	Transcriptional regulator
AL504_RS02145	COG4941	Belongs to the sigma-70 factor family
AL504_RS02155	COG3795	YCII-related domain
AL504_RS02160	COG3795	YCII-related domain
AL504_RS02175	COG3047	cAMP biosynthetic process
AL504_RS02175	COG2885	chlorophyll binding
AL504_RS02195	COG2207	Transcriptional regulator
AL504_RS02210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL504_RS02215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL504_RS02220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL504_RS02225	COG0084	hydrolase, TatD family'
AL504_RS02240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS02245	COG0765	amino acid transport
AL504_RS02250	COG1126	abc transporter atp-binding protein
AL504_RS02255	COG0010	Belongs to the arginase family
AL504_RS02265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL504_RS02275	COG0095	Lipoate-protein ligase
AL504_RS02290	COG0625	glutathione transferase activity
AL504_RS02300	COG1522	sequence-specific DNA binding
AL504_RS02305	COG0386	Belongs to the glutathione peroxidase family
AL504_RS02310	COG2814	Major facilitator Superfamily
AL504_RS02335	COG3395	kinase activity
AL504_RS02340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL504_RS02350	COG0840	transmembrane signaling receptor activity
AL504_RS02360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS02385	COG0513	Belongs to the DEAD box helicase family
AL504_RS02390	COG1414	Transcriptional regulator
AL504_RS02410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS02440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS02445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_RS02450	COG4521	taurine ABC transporter
AL504_RS02470	COG1966	Carbon starvation protein
AL504_RS02475	COG2879	small protein
AL504_RS02480	COG0697	spore germination
AL504_RS02485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS02505	COG0783	Belongs to the Dps family
AL504_RS02520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_RS02525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_RS02535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL504_RS02540	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AL504_RS02545	COG0745	RESPONSE REGULATOR receiver
AL504_RS02550	COG5002	protein histidine kinase activity
AL504_RS02555	COG2070	2-Nitropropane dioxygenase
AL504_RS02575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS02615	COG0583	DNA-binding transcription factor activity
AL504_RS02630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS02635	COG0583	DNA-binding transcription factor activity
AL504_RS02660	COG2223	nitrite transmembrane transporter activity
AL504_RS02670	COG1140	nitrate reductase beta subunit
AL504_RS02675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL504_RS02680	COG2181	nitrate reductase activity
AL504_RS02685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS02690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL504_RS02695	COG0288	reversible hydration of carbon dioxide
AL504_RS02700	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL504_RS02705	COG3850	Histidine kinase
AL504_RS02710	COG2197	response regulator
AL504_RS02715	COG0826	peptidase U32
AL504_RS02720	COG0826	peptidase U32
AL504_RS02725	COG3154	lipid carrier protein
AL504_RS02730	COG4597	amino acid ABC transporter
AL504_RS02735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS02740	COG1104	cysteine desulfurase activity
AL504_RS02770	COG1116	anion transmembrane transporter activity
AL504_RS02775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS02780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS02810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL504_RS02825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS02830	COG1802	Transcriptional regulator
AL504_RS02840	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS02865	COG1132	(ABC) transporter
AL504_RS02865	COG2375	cellular response to nickel ion
AL504_RS02875	COG4774	siderophore transport
AL504_RS02880	COG1309	transcriptional regulator
AL504_RS02900	COG0251	oxidation-reduction process
AL504_RS02925	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL504_RS02945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS02950	COG0277	FAD linked oxidase domain protein
AL504_RS02955	COG0436	Aminotransferase
AL504_RS02960	COG0765	amino acid transport
AL504_RS02970	COG1126	abc transporter atp-binding protein
AL504_RS02990	COG0583	DNA-binding transcription factor activity
AL504_RS03025	COG4774	siderophore transport
AL504_RS03055	COG4566	intracellular signal transduction
AL504_RS03060	COG4191	Histidine kinase
AL504_RS03070	COG1846	Transcriptional regulator
AL504_RS03085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL504_RS03115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL504_RS03125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS03130	COG2070	2-Nitropropane dioxygenase
AL504_RS03135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS03140	COG0765	amino acid transport
AL504_RS03145	COG1126	abc transporter atp-binding protein
AL504_RS03150	COG1595	DNA-templated transcription, initiation
AL504_RS03155	COG3712	iron ion homeostasis
AL504_RS03160	COG4774	siderophore transport
AL504_RS03220	COG0657	acetylesterase activity
AL504_RS03225	COG4774	siderophore transport
AL504_RS03255	COG1120	ATPase activity
AL504_RS03260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS03265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS03270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL504_RS03310	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AL504_RS03315	COG1136	(ABC) transporter
AL504_RS03320	COG0390	transport system, permease component
AL504_RS03325	COG0586	Pfam SNARE associated Golgi protein
AL504_RS03340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL504_RS03345	COG1120	ATPase activity
AL504_RS03350	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL504_RS03355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS03365	COG0745	RESPONSE REGULATOR receiver
AL504_RS03370	COG0642	Histidine kinase
AL504_RS03380	COG1126	abc transporter atp-binding protein
AL504_RS03385	COG0765	amino acid transport
AL504_RS03390	COG4597	amino acid ABC transporter
AL504_RS03395	COG0436	Aminotransferase
AL504_RS03400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS03405	COG2188	Transcriptional regulator
AL504_RS03425	COG2721	sulfolactate sulfo-lyase activity
AL504_RS03430	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS03455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL504_RS03455	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS03460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS03470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS03490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_RS03495	COG4208	sulfate ABC transporter
AL504_RS03510	COG1335	isochorismatase
AL504_RS03515	COG0583	DNA-binding transcription factor activity
AL504_RS03525	COG0747	negative chemotaxis
AL504_RS03530	COG0601	transmembrane transport
AL504_RS03535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS03540	COG0444	Belongs to the ABC transporter superfamily
AL504_RS03550	COG4771	TonB-dependent receptor
AL504_RS03555	COG0583	DNA-binding transcription factor activity
AL504_RS03560	COG0626	cystathionine gamma-synthase activity
AL504_RS03565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS03570	COG4597	amino acid ABC transporter
AL504_RS03575	COG0765	amino acid transport
AL504_RS03580	COG1126	abc transporter atp-binding protein
AL504_RS03600	COG0583	DNA-binding transcription factor activity
AL504_RS03605	COG2957	Belongs to the agmatine deiminase family
AL504_RS03610	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AL504_RS03615	COG0583	DNA-binding transcription factor activity
AL504_RS03635	COG2207	Transcriptional regulator
AL504_RS03650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL504_RS03680	COG0583	DNA-binding transcription factor activity
AL504_RS03705	COG1733	regulation of RNA biosynthetic process
AL504_RS03745	COG0579	oxidoreductase
AL504_RS03770	COG0625	glutathione transferase activity
AL504_RS03795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS03815	COG3971	2-oxopent-4-enoate hydratase activity
AL504_RS03840	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL504_RS03855	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS03875	COG0251	oxidation-reduction process
AL504_RS03885	COG0747	negative chemotaxis
AL504_RS03890	COG0601	transmembrane transport
AL504_RS03900	COG0444	Belongs to the ABC transporter superfamily
AL504_RS03905	COG4608	Belongs to the ABC transporter superfamily
AL504_RS03910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS03925	COG2226	methyltransferase
AL504_RS03940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL504_RS03945	COG0626	cystathionine gamma-synthase activity
AL504_RS03950	COG0628	permease
AL504_RS03960	COG0583	DNA-binding transcription factor activity
AL504_RS03965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_RS03990	COG3706	GGDEF domain
AL504_RS04000	COG0789	Transcriptional regulator
AL504_RS04005	COG3706	GGDEF domain
AL504_RS04145	COG0667	Aldo Keto reductase
AL504_RS04150	COG0583	DNA-binding transcription factor activity
AL504_RS04165	COG2205	protein histidine kinase activity
AL504_RS04190	COG1253	flavin adenine dinucleotide binding
AL504_RS04240	COG5001	Diguanylate cyclase
AL504_RS04240	COG3300	MHYT domain
AL504_RS04245	COG1289	transmembrane transporter activity
AL504_RS04265	COG0693	protein deglycase activity
AL504_RS04285	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS04315	COG2204	response regulator
AL504_RS04320	COG2204	response regulator
AL504_RS04325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL504_RS04345	COG4771	TonB-dependent receptor
AL504_RS04365	COG2375	cellular response to nickel ion
AL504_RS04365	COG1132	(ABC) transporter
AL504_RS04370	COG1132	(ABC) transporter
AL504_RS04385	COG2814	Major facilitator Superfamily
AL504_RS04405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL504_RS04410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS04435	COG0488	(ABC) transporter
AL504_RS04445	COG0688	phosphatidylethanolamine metabolic process
AL504_RS04475	COG1408	metallophosphoesterase
AL504_RS04485	COG2814	Major facilitator Superfamily
AL504_RS04500	COG0010	Belongs to the arginase family
AL504_RS04510	COG2363	Small membrane protein
AL504_RS04515	COG0697	spore germination
AL504_RS04525	COG2133	pyrroloquinoline quinone binding
AL504_RS04530	COG0625	glutathione transferase activity
AL504_RS04535	COG0583	DNA-binding transcription factor activity
AL504_RS04545	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS04550	COG1794	racemase activity, acting on amino acids and derivatives
AL504_RS04570	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS04580	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL504_RS04590	COG1653	transport
AL504_RS04595	COG1175	transmembrane transport
AL504_RS04600	COG0395	ABC-type sugar transport system, permease component
AL504_RS04605	COG3842	ATPase activity
AL504_RS04620	COG2205	protein histidine kinase activity
AL504_RS04625	COG0745	RESPONSE REGULATOR receiver
AL504_RS04640	COG3866	Pectate lyase
AL504_RS04645	COG1560	Kdo2-lipid A biosynthetic process
AL504_RS04645	COG4783	chaperone-mediated protein folding
AL504_RS04670	COG0438	transferase activity, transferring glycosyl groups
AL504_RS04675	COG0457	Tetratricopeptide repeat
AL504_RS04685	COG0783	Belongs to the Dps family
AL504_RS04695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL504_RS04715	COG0583	DNA-binding transcription factor activity
AL504_RS04740	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_RS04745	COG4149	molybdate abc transporter
AL504_RS04750	COG3842	ATPase activity
AL504_RS04755	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS04760	COG1690	Belongs to the RtcB family
AL504_RS04765	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL504_RS04770	COG1741	Belongs to the pirin family
AL504_RS04775	COG1741	Belongs to the pirin family
AL504_RS04780	COG0583	DNA-binding transcription factor activity
AL504_RS04795	COG0174	glutamine synthetase
AL504_RS04800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL504_RS04805	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL504_RS04815	COG1960	acyl-CoA dehydrogenase activity
AL504_RS04825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL504_RS04830	COG1561	YicC-like family, N-terminal region
AL504_RS04835	COG0833	amino acid
AL504_RS04840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL504_RS04855	COG0791	NLP P60 protein
AL504_RS04860	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS04865	COG2863	cytochrome
AL504_RS04870	COG3258	Cytochrome c
AL504_RS04875	COG0194	GDP metabolic process
AL504_RS04880	COG1758	RNA polymerase activity
AL504_RS04885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL504_RS04895	COG1335	isochorismatase
AL504_RS04900	COG1126	abc transporter atp-binding protein
AL504_RS04905	COG0765	amino acid transport
AL504_RS04910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS04930	COG2816	NAD+ diphosphatase activity
AL504_RS04950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS04980	COG4336	lyase activity
AL504_RS04985	COG0583	DNA-binding transcription factor activity
AL504_RS05000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS05015	COG0583	DNA-binding transcription factor activity
AL504_RS05025	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL504_RS05035	COG0583	DNA-binding transcription factor activity
AL504_RS05040	COG3842	ATPase activity
AL504_RS05045	COG1178	ABC-type Fe3 transport system permease component
AL504_RS05055	COG4181	ATPase activity
AL504_RS05065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS05075	COG0584	glycerophosphoryl diester phosphodiesterase
AL504_RS05080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL504_RS05090	COG2986	histidine ammonia-lyase
AL504_RS05100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL504_RS05100	COG0678	peroxiredoxin activity
AL504_RS05115	COG0789	Transcriptional regulator
AL504_RS05120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL504_RS05145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL504_RS05155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL504_RS05160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL504_RS05165	COG2252	PERMEase
AL504_RS05175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS05180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS05215	COG0488	(ABC) transporter
AL504_RS05220	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL504_RS05225	COG0590	tRNA wobble adenosine to inosine editing
AL504_RS05240	COG1320	monovalent cation:proton antiporter activity
AL504_RS05245	COG2212	antiporter activity
AL504_RS05250	COG1863	multisubunit Na H antiporter MnhE subunit
AL504_RS05255	COG0651	ATP synthesis coupled electron transport
AL504_RS05260	COG1006	Multisubunit Na H antiporter MnhC subunit
AL504_RS05275	COG4774	siderophore transport
AL504_RS05280	COG4774	siderophore transport
AL504_RS05305	COG0420	3'-5' exonuclease activity
AL504_RS05310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS05350	COG1960	acyl-CoA dehydrogenase activity
AL504_RS05355	COG1959	2 iron, 2 sulfur cluster binding
AL504_RS05360	COG3634	alkyl hydroperoxide reductase activity
AL504_RS05385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS05390	COG0346	lactoylglutathione lyase activity
AL504_RS05430	COG0395	ABC-type sugar transport system, permease component
AL504_RS05440	COG3842	ATPase activity
AL504_RS05470	COG2130	NADP-dependent
AL504_RS05485	COG1131	(ABC) transporter
AL504_RS05490	COG0842	Transport permease protein
AL504_RS05505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL504_RS05535	COG1902	pentaerythritol trinitrate reductase activity
AL504_RS05550	COG0602	queuosine metabolic process
AL504_RS05555	COG0720	synthase
AL504_RS05565	COG1289	transmembrane transporter activity
AL504_RS05575	COG1566	PFAM secretion protein HlyD family protein
AL504_RS05590	COG0028	Belongs to the TPP enzyme family
AL504_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS05610	COG0400	carboxylic ester hydrolase activity
AL504_RS05615	COG0833	amino acid
AL504_RS05650	COG0667	Aldo Keto reductase
AL504_RS05660	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL504_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS05690	COG0583	DNA-binding transcription factor activity
AL504_RS05705	COG0765	amino acid transport
AL504_RS05710	COG0765	amino acid transport
AL504_RS05715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS05720	COG0436	Aminotransferase
AL504_RS05780	COG0840	transmembrane signaling receptor activity
AL504_RS05865	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL504_RS05885	COG4774	siderophore transport
AL504_RS05890	COG2345	Transcriptional regulator
AL504_RS05900	COG1414	Transcriptional regulator
AL504_RS05910	COG0477	Major facilitator Superfamily
AL504_RS05920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS05925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS05935	COG0667	Aldo Keto reductase
AL504_RS05945	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS05950	COG1309	transcriptional regulator
AL504_RS05965	COG1683	Conserved Protein
AL504_RS05985	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS05985	COG1024	Enoyl-CoA hydratase
AL504_RS06000	COG2867	negative regulation of translational initiation
AL504_RS06005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL504_RS06025	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS06025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL504_RS06030	COG2169	Transcriptional regulator
AL504_RS06030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL504_RS06070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL504_RS06075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL504_RS06090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL504_RS06095	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL504_RS06100	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL504_RS06105	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL504_RS06110	COG0750	zinc metalloprotease
AL504_RS06115	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL504_RS06125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL504_RS06130	COG0233	cytoplasmic translational termination
AL504_RS06135	COG0528	UMP kinase activity
AL504_RS06140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL504_RS06145	COG0052	Belongs to the universal ribosomal protein uS2 family
AL504_RS06150	COG0024	Methionine aminopeptidase
AL504_RS06155	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL504_RS06165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL504_RS06170	COG1451	nucleotide metabolic process
AL504_RS06190	COG0285	dihydrofolate synthase activity
AL504_RS06200	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS06205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS06225	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL504_RS06245	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL504_RS06255	COG1677	Flagellar hook-basal body complex protein FliE
AL504_RS06260	COG1766	The M ring may be actively involved in energy transduction
AL504_RS06265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL504_RS06290	COG1580	Controls the rotational direction of flagella during chemotaxis
AL504_RS06325	COG0840	transmembrane signaling receptor activity
AL504_RS06330	COG0840	transmembrane signaling receptor activity
AL504_RS06340	COG0840	transmembrane signaling receptor activity
AL504_RS06345	COG0840	transmembrane signaling receptor activity
AL504_RS06355	COG1256	bacterial-type flagellum assembly
AL504_RS06395	COG1558	bacterial-type flagellum-dependent cell motility
AL504_RS06400	COG1815	bacterial-type flagellum-dependent cell motility
AL504_RS06410	COG2747	anti-sigma28 factor FlgM
AL504_RS06435	COG0840	transmembrane signaling receptor activity
AL504_RS06440	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL504_RS06445	COG0745	RESPONSE REGULATOR receiver
AL504_RS06450	COG2201	protein-glutamate methylesterase activity
AL504_RS06455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL504_RS06460	COG0840	transmembrane signaling receptor activity
AL504_RS06465	COG0835	chemotaxis
AL504_RS06475	COG0745	RESPONSE REGULATOR receiver
AL504_RS06505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_RS06505	COG4797	methyltransferase
AL504_RS06540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL504_RS06550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL504_RS06580	COG0583	DNA-binding transcription factor activity
AL504_RS06590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL504_RS06595	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL504_RS06600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL504_RS06610	COG4566	intracellular signal transduction
AL504_RS06615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL504_RS06620	COG0339	signal peptide processing
AL504_RS06630	COG1999	signal sequence binding
AL504_RS06655	COG0583	DNA-binding transcription factor activity
AL504_RS06660	COG1187	pseudouridine synthase activity
AL504_RS06665	COG3161	chorismate lyase activity
AL504_RS06685	COG2130	NADP-dependent
AL504_RS06690	COG1309	transcriptional regulator
AL504_RS06695	COG4681	YaeQ
AL504_RS06700	COG4172	Belongs to the ABC transporter superfamily
AL504_RS06705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS06710	COG0601	transmembrane transport
AL504_RS06715	COG0747	negative chemotaxis
AL504_RS06725	COG0583	DNA-binding transcription factor activity
AL504_RS06755	COG2165	general secretion pathway protein
AL504_RS06825	COG0668	transmembrane transport
AL504_RS06830	COG0165	Argininosuccinate lyase
AL504_RS06850	COG0022	dehydrogenase e1 component
AL504_RS06860	COG4774	siderophore transport
AL504_RS06885	COG0789	Transcriptional regulator
AL504_RS06905	COG2271	Major facilitator Superfamily
AL504_RS06915	COG0307	riboflavin synthase, alpha
AL504_RS06930	COG1696	Membrane protein involved in D-alanine export
AL504_RS06940	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS06975	COG2070	2-Nitropropane dioxygenase
AL504_RS07025	COG0154	amidase activity
AL504_RS07030	COG2814	Major facilitator Superfamily
AL504_RS07040	COG2226	methyltransferase
AL504_RS07050	COG4608	Belongs to the ABC transporter superfamily
AL504_RS07055	COG0444	Belongs to the ABC transporter superfamily
AL504_RS07065	COG0601	transmembrane transport
AL504_RS07070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS07095	COG0747	negative chemotaxis
AL504_RS07130	COG0583	DNA-binding transcription factor activity
AL504_RS07145	COG1733	regulation of RNA biosynthetic process
AL504_RS07155	COG0583	DNA-binding transcription factor activity
AL504_RS07160	COG1132	(ABC) transporter
AL504_RS07205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS07220	COG1280	lysine exporter protein (LysE YggA)
AL504_RS07260	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS07265	COG2188	Transcriptional regulator
AL504_RS07280	COG0477	Major facilitator Superfamily
AL504_RS07285	COG0235	Class ii aldolase
AL504_RS07315	COG2610	gluconate transmembrane transporter activity
AL504_RS07320	COG0583	DNA-binding transcription factor activity
AL504_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07335	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AL504_RS07380	COG1024	Enoyl-CoA hydratase
AL504_RS07385	COG5001	Diguanylate cyclase
AL504_RS07390	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS07395	COG0129	dihydroxy-acid dehydratase activity
AL504_RS07405	COG0583	DNA-binding transcription factor activity
AL504_RS07410	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS07415	COG3246	L-lysine catabolic process to acetate
AL504_RS07430	COG0243	molybdopterin cofactor binding
AL504_RS07435	COG3043	anaerobic respiration
AL504_RS07440	COG3005	denitrification pathway
AL504_RS07445	COG4133	protoheme IX ABC transporter activity
AL504_RS07460	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL504_RS07495	COG3381	protein complex oligomerization
AL504_RS07510	COG4133	protoheme IX ABC transporter activity
AL504_RS07520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL504_RS07530	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL504_RS07540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS07545	COG3088	subunit of a heme lyase
AL504_RS07565	COG0109	protoheme IX farnesyltransferase activity
AL504_RS07570	COG0583	DNA-binding transcription factor activity
AL504_RS07585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS07595	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07615	COG2207	Transcriptional regulator
AL504_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07665	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AL504_RS07670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL504_RS07680	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL504_RS07690	COG0534	Mate efflux family protein
AL504_RS07705	COG0697	spore germination
AL504_RS07710	COG0697	spore germination
AL504_RS07725	COG1280	lysine exporter protein (LysE YggA)
AL504_RS07740	COG1280	lysine exporter protein (LysE YggA)
AL504_RS07750	COG3245	cytochrome
AL504_RS07760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL504_RS07770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL504_RS07795	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS07800	COG1960	acyl-CoA dehydrogenase activity
AL504_RS07815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_RS07825	COG2814	Major facilitator Superfamily
AL504_RS07850	COG0583	DNA-binding transcription factor activity
AL504_RS07860	COG0583	DNA-binding transcription factor activity
AL504_RS07880	COG0506	proline dehydrogenase activity
AL504_RS07885	COG0697	spore germination
AL504_RS07890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS07895	COG1959	2 iron, 2 sulfur cluster binding
AL504_RS07920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL504_RS07935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL504_RS07975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL504_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL504_RS08000	COG1610	YqeY-like protein
AL504_RS08035	COG0457	Tetratricopeptide repeat
AL504_RS08040	COG0726	polysaccharide deacetylase
AL504_RS08040	COG1649	PFAM Uncharacterised BCR, COG1649
AL504_RS08045	COG1215	transferase activity, transferring glycosyl groups
AL504_RS08055	COG2223	nitrite transmembrane transporter activity
AL504_RS08060	COG4977	sequence-specific DNA binding
AL504_RS08060	COG1917	Cupin 2, conserved barrel domain protein
AL504_RS08070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL504_RS08085	COG0656	L-ascorbic acid biosynthetic process
AL504_RS08090	COG5265	(ABC) transporter
AL504_RS08120	COG1116	anion transmembrane transporter activity
AL504_RS08145	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS08150	COG0583	DNA-binding transcription factor activity
AL504_RS08180	COG1522	sequence-specific DNA binding
AL504_RS08205	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS08220	COG0456	acetyltransferase
AL504_RS08225	COG0384	phenazine biosynthesis protein PhzF
AL504_RS08250	COG0494	nUDIX hydrolase
AL504_RS08255	COG2814	Major facilitator Superfamily
AL504_RS08285	COG0072	phenylalanine-tRNA ligase activity
AL504_RS08285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_RS08290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL504_RS08295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL504_RS08300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL504_RS08310	COG2960	long-chain fatty acid transporting porin activity
AL504_RS08320	COG0347	Belongs to the P(II) protein family
AL504_RS08325	COG0004	ammonium transporteR
AL504_RS08330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL504_RS08335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL504_RS08350	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL504_RS08355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL504_RS08365	COG2197	response regulator
AL504_RS08370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL504_RS08375	COG0789	Transcriptional regulator
AL504_RS08405	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS08415	COG0601	transmembrane transport
AL504_RS08420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS08445	COG1609	Transcriptional regulator
AL504_RS08450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL504_RS08455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS08460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS08465	COG0129	dihydroxy-acid dehydratase activity
AL504_RS08470	COG2755	lipolytic protein G-D-S-L family
AL504_RS08470	COG0657	acetylesterase activity
AL504_RS08515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL504_RS08520	COG0101	tRNA pseudouridine synthase activity
AL504_RS08535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL504_RS08555	COG4783	chaperone-mediated protein folding
AL504_RS08560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL504_RS08570	COG3706	GGDEF domain
AL504_RS08575	COG5002	protein histidine kinase activity
AL504_RS08585	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL504_RS08595	COG1295	ribonuclease BN
AL504_RS08605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL504_RS08635	COG4964	Belongs to the GSP D family
AL504_RS08830	COG2369	cell adhesion
AL504_RS08840	COG5410	chromosome segregation
AL504_RS08945	COG3723	Recombinational DNA repair protein, rece pathway
AL504_RS08955	COG1475	DNA binding
AL504_RS08970	COG2755	lipolytic protein G-D-S-L family
AL504_RS08970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL504_RS08985	COG0438	transferase activity, transferring glycosyl groups
AL504_RS09010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL504_RS09015	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL504_RS09020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL504_RS09025	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AL504_RS09030	COG0330	HflC and HflK could
AL504_RS09035	COG0330	HflC and HflK could
AL504_RS09040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL504_RS09045	COG1923	regulation of RNA biosynthetic process
AL504_RS09050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL504_RS09055	COG1160	GTP binding
AL504_RS09060	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL504_RS09065	COG2976	Protein conserved in bacteria
AL504_RS09085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL504_RS09090	COG0105	UTP biosynthetic process
AL504_RS09095	COG0525	valine-tRNA ligase activity
AL504_RS09100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS09105	COG1126	abc transporter atp-binding protein
AL504_RS09110	COG0765	amino acid transport
AL504_RS09115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS09120	COG1396	sequence-specific DNA binding
AL504_RS09125	COG0336	Belongs to the RNA methyltransferase TrmD family
AL504_RS09135	COG0228	four-way junction DNA binding
AL504_RS09145	COG0425	Belongs to the sulfur carrier protein TusA family
AL504_RS09165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS09180	COG2076	Multidrug Resistance protein
AL504_RS09185	COG3217	Mosc domain protein beta barrel domain protein
AL504_RS09185	COG0633	Ferredoxin
AL504_RS09190	COG5285	phytanoyl-CoA dioxygenase
AL504_RS09195	COG0662	Cupin 2, conserved barrel domain protein
AL504_RS09220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL504_RS09230	COG1309	transcriptional regulator
AL504_RS09255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL504_RS09270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL504_RS09275	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL504_RS09295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL504_RS09305	COG3391	amine dehydrogenase activity
AL504_RS09335	COG1846	Transcriptional regulator
AL504_RS09345	COG1566	PFAM secretion protein HlyD family protein
AL504_RS09350	COG2814	Major facilitator Superfamily
AL504_RS09360	COG0473	3-isopropylmalate dehydrogenase activity
AL504_RS09365	COG0433	COG0433 Predicted ATPase
AL504_RS09370	COG0217	transcriptional regulatory protein
AL504_RS09375	COG0151	Belongs to the GarS family
AL504_RS09385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL504_RS09390	COG0799	negative regulation of ribosome biogenesis
AL504_RS09395	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL504_RS09405	COG1301	dicarboxylic acid transport
AL504_RS09410	COG4191	Histidine kinase
AL504_RS09415	COG2204	response regulator
AL504_RS09445	COG1530	ribonuclease E activity
AL504_RS09515	COG1196	nuclear chromosome segregation
AL504_RS09700	COG3723	Recombinational DNA repair protein, rece pathway
AL504_RS09770	COG4251	negative regulation of phosphorylation
AL504_RS09770	COG2203	Gaf domain
AL504_RS09770	COG3706	GGDEF domain
AL504_RS09770	COG5001	Diguanylate cyclase
AL504_RS09785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL504_RS09785	COG0475	glutathione-regulated potassium exporter activity
AL504_RS09790	COG1132	(ABC) transporter
AL504_RS09815	COG0726	polysaccharide deacetylase
AL504_RS09830	COG0726	polysaccharide deacetylase
AL504_RS09835	COG0438	transferase activity, transferring glycosyl groups
AL504_RS09850	COG1116	anion transmembrane transporter activity
AL504_RS09855	COG0395	ABC-type sugar transport system, permease component
AL504_RS09860	COG1643	Atp-dependent helicase
AL504_RS09865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL504_RS09865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL504_RS09870	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL504_RS09880	COG0704	Plays a role in the regulation of phosphate uptake
AL504_RS09890	COG1960	acyl-CoA dehydrogenase activity
AL504_RS09900	COG1322	Protein conserved in bacteria
AL504_RS09920	COG1177	transmembrane transport
AL504_RS09925	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_RS09930	COG3842	ATPase activity
AL504_RS09940	COG3642	lipopolysaccharide core region biosynthetic process
AL504_RS09950	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL504_RS09955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS09965	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS09965	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL504_RS09975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL504_RS09980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL504_RS09985	COG0596	Alpha beta hydrolase
AL504_RS09985	COG2945	thiolester hydrolase activity
AL504_RS10005	COG3618	amidohydrolase
AL504_RS10010	COG0583	DNA-binding transcription factor activity
AL504_RS10015	COG5002	protein histidine kinase activity
AL504_RS10025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS10040	COG0137	argininosuccinate synthase activity
AL504_RS10045	COG3158	transport of potassium into the cell
AL504_RS10050	COG0642	Histidine kinase
AL504_RS10080	COG0776	regulation of translation
AL504_RS10085	COG3128	pkhd-type hydroxylase
AL504_RS10095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL504_RS10100	COG0557	exoribonuclease II activity
AL504_RS10130	COG0679	Auxin Efflux Carrier
AL504_RS10135	COG2391	methyltransferase activity
AL504_RS10140	COG0069	glutamate synthase activity
AL504_RS10145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS10200	COG0697	spore germination
AL504_RS10330	COG0628	permease
AL504_RS10360	COG3909	cytochrome
AL504_RS10370	COG0625	glutathione transferase activity
AL504_RS10375	COG0730	response to heat
AL504_RS10380	COG0482	sulfurtransferase activity
AL504_RS10385	COG0583	DNA-binding transcription factor activity
AL504_RS10415	COG0247	lactate metabolic process
AL504_RS10425	COG0277	FAD linked oxidase domain protein
AL504_RS10430	COG0277	FAD linked oxidase domain protein
AL504_RS10435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL504_RS10440	COG0312	modulator of DNA gyrase
AL504_RS10455	COG0308	aminopeptidase N
AL504_RS10480	COG0436	Aminotransferase
AL504_RS10490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL504_RS10500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL504_RS10520	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS10550	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS10580	COG0181	hydroxymethylbilane synthase activity
AL504_RS10585	COG0861	Integral membrane protein TerC family
AL504_RS10590	COG0861	Integral membrane protein TerC family
AL504_RS10595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL504_RS10600	COG0045	succinate-CoA ligase (ADP-forming) activity
AL504_RS10625	COG2137	regulation of response to DNA damage stimulus
AL504_RS10630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL504_RS10665	COG0540	Belongs to the ATCase OTCase family
AL504_RS10760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL504_RS10770	COG0305	Participates in initiation and elongation during chromosome replication
AL504_RS10780	COG0359	binds to the 23S rRNA
AL504_RS10785	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL504_RS10790	COG2965	DNA replication, synthesis of RNA primer
AL504_RS10795	COG0360	Binds together with S18 to 16S ribosomal RNA
AL504_RS10800	COG3739	integral membrane protein
AL504_RS10805	COG1469	GTP cyclohydrolase I activity
AL504_RS10815	COG0142	geranyltranstransferase activity
AL504_RS10820	COG1722	exodeoxyribonuclease VII activity
AL504_RS10830	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS10850	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_RS10855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL504_RS10865	COG3842	ATPase activity
AL504_RS10870	COG0583	DNA-binding transcription factor activity
AL504_RS10890	COG0501	Belongs to the peptidase M48B family
AL504_RS10895	COG1760	l-serine dehydratase
AL504_RS10900	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL504_RS10905	COG2801	Transposase and inactivated derivatives
AL504_RS10905	COG3415	Transposase
AL504_RS10915	COG0412	Dienelactone hydrolase
AL504_RS10930	COG1611	Belongs to the LOG family
AL504_RS10935	COG1473	amidohydrolase
AL504_RS10940	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS10960	COG1217	gtp-binding protein TYPA
AL504_RS10965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL504_RS10970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL504_RS10980	COG0195	Participates in both transcription termination and antitermination
AL504_RS10980	COG2251	uridine kinase activity
AL504_RS10985	COG0779	Required for maturation of 30S ribosomal subunits
AL504_RS10990	COG1187	pseudouridine synthase activity
AL504_RS10995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL504_RS11005	COG0583	DNA-binding transcription factor activity
AL504_RS11010	COG0523	cobalamin synthesis protein
AL504_RS11015	COG0523	cobalamin synthesis protein
AL504_RS11040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_RS11045	COG0625	glutathione transferase activity
AL504_RS11050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL504_RS11060	COG2003	Belongs to the UPF0758 family
AL504_RS11065	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL504_RS11070	COG3483	tryptophan 2,3-dioxygenase activity
AL504_RS11085	COG0534	Mate efflux family protein
AL504_RS11095	COG2050	protein possibly involved in aromatic compounds catabolism
AL504_RS11100	COG1024	Enoyl-CoA hydratase
AL504_RS11105	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS11110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL504_RS11115	COG2151	metal-sulfur cluster biosynthetic enzyme
AL504_RS11120	COG3396	Phenylacetate-CoA oxygenase
AL504_RS11125	COG3460	Phenylacetate-CoA oxygenase
AL504_RS11130	COG3396	Phenylacetate-CoA oxygenase
AL504_RS11135	COG3327	negative regulation of DNA-templated transcription, initiation
AL504_RS11140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL504_RS11145	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL504_RS11150	COG0501	Belongs to the peptidase M48B family
AL504_RS11155	COG1162	GTPase activity
AL504_RS11165	COG0335	large ribosomal subunit rRNA binding
AL504_RS11195	COG0175	sulfate reduction
AL504_RS11205	COG4208	sulfate ABC transporter
AL504_RS11210	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL504_RS11220	COG0450	alkyl hydroperoxide reductase
AL504_RS11225	COG1960	acyl-CoA dehydrogenase activity
AL504_RS11230	COG2985	domain, Protein
AL504_RS11255	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL504_RS11260	COG2951	lytic endotransglycosylase activity
AL504_RS11290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS11295	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL504_RS11300	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL504_RS11320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL504_RS11325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL504_RS11335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL504_RS11345	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL504_RS11360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL504_RS11395	COG2951	lytic endotransglycosylase activity
AL504_RS11410	COG1132	(ABC) transporter
AL504_RS11415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL504_RS11415	COG0189	ligase activity
AL504_RS11420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL504_RS11420	COG0189	ligase activity
AL504_RS11425	COG3237	CsbD-like
AL504_RS11430	COG2823	Periplasmic or secreted lipoprotein
AL504_RS11450	COG2831	hemolysin activation secretion protein
AL504_RS11475	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AL504_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS11485	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL504_RS11490	COG1496	oxidoreductase activity
AL504_RS11495	COG0564	pseudouridine synthase activity
AL504_RS11505	COG1199	ATP-dependent helicase activity
AL504_RS11545	COG4774	siderophore transport
AL504_RS11550	COG3712	iron ion homeostasis
AL504_RS11555	COG1595	DNA-templated transcription, initiation
AL504_RS11560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL504_RS11565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL504_RS11575	COG0567	Dehydrogenase, E1 component
AL504_RS11580	COG1522	sequence-specific DNA binding
AL504_RS11585	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL504_RS11600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_RS11605	COG1297	OPT oligopeptide transporter protein
AL504_RS11615	COG0281	malic enzyme
AL504_RS11615	COG0280	phosphate acetyltransferase
AL504_RS11630	COG0372	Belongs to the citrate synthase family
AL504_RS11635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL504_RS11640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL504_RS11645	COG1053	succinate dehydrogenase
AL504_RS11650	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL504_RS11655	COG2009	succinate dehydrogenase
AL504_RS11660	COG2188	Transcriptional regulator
AL504_RS11665	COG0039	L-malate dehydrogenase activity
AL504_RS11685	COG1981	membrane
AL504_RS11720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL504_RS11730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL504_RS11740	COG0148	phosphopyruvate hydratase activity
AL504_RS11750	COG0504	CTP synthase activity
AL504_RS11785	COG0747	negative chemotaxis
AL504_RS11790	COG4172	Belongs to the ABC transporter superfamily
AL504_RS11795	COG1446	asparaginase
AL504_RS11805	COG2153	protein acetylation
AL504_RS11830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS11850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL504_RS11855	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL504_RS11860	COG0697	spore germination
AL504_RS11865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL504_RS11875	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AL504_RS11885	COG0791	NLP P60 protein
AL504_RS11895	COG0583	DNA-binding transcription factor activity
AL504_RS11920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL504_RS11950	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS11960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL504_RS11970	COG1381	Involved in DNA repair and RecF pathway recombination
AL504_RS11975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL504_RS11980	COG0571	ribonuclease III activity
AL504_RS11985	COG0681	Belongs to the peptidase S26 family
AL504_RS11995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_RS12020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL504_RS12025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL504_RS12035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL504_RS12040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL504_RS12050	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL504_RS12060	COG0424	maF-like protein
AL504_RS12070	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL504_RS12075	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL504_RS12080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL504_RS12085	COG0546	phosphoglycolate phosphatase activity
AL504_RS12090	COG0564	pseudouridine synthase activity
AL504_RS12110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL504_RS12115	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL504_RS12120	COG0159	tryptophan synthase activity
AL504_RS12130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_RS12145	COG3228	Belongs to the MtfA family
AL504_RS12155	COG0251	oxidation-reduction process
AL504_RS12160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL504_RS12180	COG2878	Part of a membrane complex involved in electron transport
AL504_RS12185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL504_RS12220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL504_RS12255	COG1268	BioY protein
AL504_RS12260	COG1268	BioY protein
AL504_RS12265	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AL504_RS12270	COG1122	ATPase activity
AL504_RS12275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_RS12280	COG2917	probably involved in intracellular septation
AL504_RS12290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS12295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL504_RS12315	COG1573	uracil-dna glycosylase
AL504_RS12320	COG1214	PFAM Peptidase M22, glycoprotease
AL504_RS12335	COG0450	alkyl hydroperoxide reductase
AL504_RS12340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS12350	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL504_RS12355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL504_RS12360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL504_RS12365	COG0560	Phosphoserine phosphatase
AL504_RS12370	COG3210	domain, Protein
AL504_RS12380	COG4774	siderophore transport
AL504_RS12390	COG1007	ATP synthesis coupled electron transport
AL504_RS12405	COG0713	ATP synthesis coupled electron transport
AL504_RS12415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_RS12420	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL504_RS12425	COG1034	ATP synthesis coupled electron transport
AL504_RS12435	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL504_RS12440	COG0649	NAD binding
AL504_RS12445	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_RS12450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_RS12455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_RS12460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS12485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_RS12490	COG1597	lipid kinase activity
AL504_RS12510	COG1309	transcriptional regulator
AL504_RS12520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS12540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS12545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS12550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL504_RS12605	COG0747	negative chemotaxis
AL504_RS12635	COG1522	sequence-specific DNA binding
AL504_RS12640	COG2354	Protein conserved in bacteria
AL504_RS12650	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AL504_RS12655	COG3604	Transcriptional regulator
AL504_RS12670	COG1595	DNA-templated transcription, initiation
AL504_RS12695	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS12700	COG2851	Citrate transporter
AL504_RS12710	COG0642	Histidine kinase
AL504_RS12720	COG4566	intracellular signal transduction
AL504_RS12725	COG4191	Histidine kinase
AL504_RS12755	COG0659	secondary active sulfate transmembrane transporter activity
AL504_RS12765	COG3712	iron ion homeostasis
AL504_RS12770	COG1595	DNA-templated transcription, initiation
AL504_RS12800	COG1116	anion transmembrane transporter activity
AL504_RS12835	COG1910	domain protein
AL504_RS12845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL504_RS12885	COG0840	transmembrane signaling receptor activity
AL504_RS12910	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL504_RS12915	COG0149	triose-phosphate isomerase activity
AL504_RS12920	COG0604	alcohol dehydrogenase
AL504_RS12920	COG3321	synthase
AL504_RS12940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS12950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS12975	COG2819	hydrolase of the alpha beta superfamily
AL504_RS12990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL504_RS13000	COG1185	polyribonucleotide nucleotidyltransferase activity
AL504_RS13005	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL504_RS13015	COG1183	phosphatidylcholine synthase activity
AL504_RS13020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL504_RS13025	COG0440	acetolactate synthase activity
AL504_RS13030	COG0028	Belongs to the TPP enzyme family
AL504_RS13035	COG1289	transmembrane transporter activity
AL504_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS13065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS13100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL504_RS13105	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL504_RS13110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL504_RS13125	COG0601	transmembrane transport
AL504_RS13145	COG0517	IMP dehydrogenase activity
AL504_RS13145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL504_RS13150	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS13155	COG0251	oxidation-reduction process
AL504_RS13160	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL504_RS13165	COG1674	ftsk spoiiie
AL504_RS13170	COG0492	ferredoxin-NADP+ reductase activity
AL504_RS13175	COG1193	negative regulation of DNA recombination
AL504_RS13185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL504_RS13205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL504_RS13210	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL504_RS13215	COG2205	protein histidine kinase activity
AL504_RS13220	COG0745	RESPONSE REGULATOR receiver
AL504_RS13235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS13240	COG0840	transmembrane signaling receptor activity
AL504_RS13275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL504_RS13300	COG0612	Peptidase, M16
AL504_RS13310	COG0484	heat shock protein binding
AL504_RS13315	COG0443	Heat shock 70 kDa protein
AL504_RS13325	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL504_RS13335	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL504_RS13340	COG1420	regulation of RNA biosynthetic process
AL504_RS13350	COG0497	DNA recombination
AL504_RS13355	COG0735	belongs to the Fur family
AL504_RS13360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL504_RS13370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL504_RS13440	COG0583	DNA-binding transcription factor activity
AL504_RS13450	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL504_RS13455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL504_RS13460	COG0167	dihydroorotate dehydrogenase activity
AL504_RS13475	COG1414	Transcriptional regulator
AL504_RS13480	COG1058	Belongs to the CinA family
AL504_RS13480	COG1546	Belongs to the CinA family
AL504_RS13495	COG0513	Belongs to the DEAD box helicase family
AL504_RS13505	COG4771	TonB-dependent receptor
AL504_RS13510	COG2814	Major facilitator Superfamily
AL504_RS13550	COG4783	chaperone-mediated protein folding
AL504_RS13565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS13585	COG0006	proline dipeptidase activity
AL504_RS13595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_RS13620	COG0632	four-way junction helicase activity
AL504_RS13625	COG1090	epimerase
AL504_RS13635	COG2255	four-way junction helicase activity
AL504_RS13640	COG3290	protein histidine kinase activity
AL504_RS13655	COG0514	ATP-dependent DNA helicase (RecQ)
AL504_RS13670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL504_RS13680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS13685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS13690	COG1414	Transcriptional regulator
AL504_RS13700	COG2894	cell division
AL504_RS13705	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL504_RS13720	COG0488	(ABC) transporter
AL504_RS13725	COG2746	aminoglycoside 3-N-acetyltransferase activity
AL504_RS13745	COG4608	Belongs to the ABC transporter superfamily
AL504_RS13750	COG0444	Belongs to the ABC transporter superfamily
AL504_RS13755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS13760	COG0601	transmembrane transport
AL504_RS13765	COG0747	negative chemotaxis
AL504_RS13790	COG4638	Rieske (2fe-2S)
AL504_RS13815	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL504_RS13820	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS13845	COG1216	Glycosyl transferase, family 2
AL504_RS13845	COG0463	Glycosyl transferase, family 2
AL504_RS13865	COG0800	Aldolase
AL504_RS13875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL504_RS13890	COG1595	DNA-templated transcription, initiation
AL504_RS13895	COG3712	iron ion homeostasis
AL504_RS13925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL504_RS13930	COG1538	Outer membrane efflux protein
AL504_RS13935	COG1136	(ABC) transporter
AL504_RS13935	COG0577	efflux transmembrane transporter activity
AL504_RS13940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS13955	COG0259	pyridoxamine-phosphate oxidase activity
AL504_RS13960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS13965	COG0579	oxidoreductase
AL504_RS13975	COG0583	DNA-binding transcription factor activity
AL504_RS13985	COG2175	clavaminate synthase activity
AL504_RS14005	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS14010	COG0583	DNA-binding transcription factor activity
AL504_RS14015	COG1960	acyl-CoA dehydrogenase activity
AL504_RS14025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS14030	COG0531	amino acid
AL504_RS14035	COG0405	Gamma-glutamyltransferase
AL504_RS14045	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS14055	COG0114	fumarate hydratase activity
AL504_RS14060	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL504_RS14070	COG0586	Pfam SNARE associated Golgi protein
AL504_RS14080	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL504_RS14090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL504_RS14105	COG0617	tRNA 3'-terminal CCA addition
AL504_RS14115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL504_RS14120	COG2301	Belongs to the HpcH HpaI aldolase family
AL504_RS14140	COG1024	Enoyl-CoA hydratase
AL504_RS14150	COG1960	acyl-CoA dehydrogenase activity
AL504_RS14165	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS14175	COG2070	2-Nitropropane dioxygenase
AL504_RS14190	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS14195	COG2030	dehydratase
AL504_RS14200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS14215	COG1024	Enoyl-CoA hydratase
AL504_RS14220	COG0752	glycyl-tRNA synthetase alpha subunit
AL504_RS14225	COG0751	glycine-tRNA ligase activity
AL504_RS14230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL504_RS14235	COG0204	Acyl-transferase
AL504_RS14255	COG0242	peptide deformylase activity
AL504_RS14265	COG0700	Nucleoside recognition
AL504_RS14270	COG0469	pyruvate kinase activity
AL504_RS14275	COG1929	Belongs to the glycerate kinase type-1 family
AL504_RS14280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL504_RS14285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS14295	COG3178	'Phosphotransferase
AL504_RS14325	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL504_RS14355	COG1595	DNA-templated transcription, initiation
AL504_RS14365	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS14380	COG2982	Protein involved in outer membrane biogenesis
AL504_RS14385	COG1368	sulfuric ester hydrolase activity
AL504_RS14390	COG2818	Glycosylase
AL504_RS14410	COG0735	belongs to the Fur family
AL504_RS14420	COG0583	DNA-binding transcription factor activity
AL504_RS14425	COG0840	transmembrane signaling receptor activity
AL504_RS14480	COG2011	ABC-type metal ion transport system permease component
AL504_RS14485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL504_RS14495	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL504_RS14495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS14500	COG0483	inositol monophosphate 1-phosphatase activity
AL504_RS14505	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS14510	COG1473	amidohydrolase
AL504_RS14525	COG2855	membrane
AL504_RS14535	COG2239	Acts as a magnesium transporter
AL504_RS14550	COG1522	sequence-specific DNA binding
AL504_RS14555	COG0300	oxidoreductase activity
AL504_RS14565	COG0028	Belongs to the TPP enzyme family
AL504_RS14570	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS14585	COG0653	protein targeting
AL504_RS14590	COG0739	heme binding
AL504_RS14600	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL504_RS14605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL504_RS14615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL504_RS14620	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL504_RS14625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL504_RS14630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL504_RS14640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL504_RS14645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL504_RS14650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL504_RS14660	COG3116	cell division
AL504_RS14665	COG0275	rRNA processing
AL504_RS14670	COG2001	Belongs to the MraZ family
AL504_RS14680	COG0488	(ABC) transporter
AL504_RS14685	COG0418	dihydroorotase activity
AL504_RS14690	COG1473	amidohydrolase
AL504_RS14700	COG0583	DNA-binding transcription factor activity
AL504_RS14740	COG1522	sequence-specific DNA binding
AL504_RS14750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_RS14755	COG4654	Cytochrome c, class I
AL504_RS14760	COG0129	dihydroxy-acid dehydratase activity
AL504_RS14805	COG2084	Dehydrogenase
AL504_RS14820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_RS14855	COG0824	Thioesterase
AL504_RS14860	COG0811	peptide transport
AL504_RS14865	COG0848	biopolymer transport protein
AL504_RS14875	COG0823	Involved in the tonB-independent uptake of proteins
AL504_RS14890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS14895	COG1120	ATPase activity
AL504_RS14910	COG1522	sequence-specific DNA binding
AL504_RS14920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL504_RS14940	COG0697	spore germination
AL504_RS14950	COG1346	cytolysis
AL504_RS14960	COG0583	DNA-binding transcription factor activity
AL504_RS14970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS14990	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS15010	COG0583	DNA-binding transcription factor activity
AL504_RS15025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL504_RS15030	COG0463	Glycosyl transferase, family 2
AL504_RS15040	COG0786	glutamate:sodium symporter activity
AL504_RS15055	COG1671	Belongs to the UPF0178 family
AL504_RS15065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL504_RS15070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS15080	COG0328	RNA-DNA hybrid ribonuclease activity
AL504_RS15085	COG2226	methyltransferase
AL504_RS15090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL504_RS15095	COG0741	lytic transglycosylase activity
AL504_RS15095	COG1388	LysM domain
AL504_RS15135	COG1366	Belongs to the anti-sigma-factor antagonist family
AL504_RS15140	COG2172	sigma factor antagonist activity
AL504_RS15145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL504_RS15155	COG2770	Histidine kinase
AL504_RS15155	COG2208	phosphoserine phosphatase activity
AL504_RS15185	COG4792	protein secretion
AL504_RS15190	COG4791	protein targeting
AL504_RS15195	COG4794	Type iii secretion
AL504_RS15200	COG4790	Type iii secretion
AL504_RS15205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL504_RS15235	COG4669	(LipO)protein
AL504_RS15305	COG4789	Type iii secretion
AL504_RS15340	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS15350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL504_RS15360	COG1942	4-Oxalocrotonate Tautomerase
AL504_RS15375	COG2719	SpoVR family
AL504_RS15380	COG2718	Belongs to the UPF0229 family
AL504_RS15385	COG2766	serine protein kinase
AL504_RS15400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL504_RS15400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL504_RS15405	COG1335	isochorismatase
AL504_RS15415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL504_RS15420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL504_RS15425	COG1280	lysine exporter protein (LysE YggA)
AL504_RS15435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL504_RS15450	COG0316	Belongs to the HesB IscA family
AL504_RS15460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL504_RS15465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL504_RS15470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL504_RS15490	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS15505	COG0312	modulator of DNA gyrase
AL504_RS15510	COG3028	Belongs to the UPF0307 family
AL504_RS15525	COG1116	anion transmembrane transporter activity
AL504_RS15530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS15535	COG1335	isochorismatase
AL504_RS15540	COG0045	succinate-CoA ligase (ADP-forming) activity
AL504_RS15540	COG1042	CoA-binding domain protein
AL504_RS15540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL504_RS15545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL504_RS15550	COG2814	Major facilitator Superfamily
AL504_RS15560	COG0583	DNA-binding transcription factor activity
AL504_RS15575	COG1522	sequence-specific DNA binding
AL504_RS15605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL504_RS15610	COG1696	Membrane protein involved in D-alanine export
AL504_RS15635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL504_RS15635	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL504_RS15645	COG2264	protein methyltransferase activity
AL504_RS15650	COG0439	Biotin carboxylase
AL504_RS15660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL504_RS15665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS15670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL504_RS15675	COG3150	esterase
AL504_RS15680	COG0557	exoribonuclease II activity
AL504_RS15700	COG1175	transmembrane transport
AL504_RS15730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL504_RS15740	COG1126	abc transporter atp-binding protein
AL504_RS15745	COG0765	amino acid transport
AL504_RS15755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS15760	COG0436	Aminotransferase
AL504_RS15765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL504_RS15790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL504_RS15795	COG1678	Uncharacterized ACR, COG1678
AL504_RS15810	COG0352	thiamine-phosphate diphosphorylase activity
AL504_RS15815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL504_RS15820	COG0741	lytic transglycosylase activity
AL504_RS15830	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS15835	COG1335	isochorismatase
AL504_RS15840	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL504_RS15845	COG4638	Rieske (2fe-2S)
AL504_RS15885	COG1024	Enoyl-CoA hydratase
AL504_RS15890	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS15925	COG0410	ABC transporter
AL504_RS15960	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL504_RS15980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS15985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS16015	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL504_RS16020	COG0237	dephospho-CoA kinase activity
AL504_RS16040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL504_RS16045	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL504_RS16055	COG0477	Major facilitator Superfamily
AL504_RS16090	COG1605	Chorismate mutase
AL504_RS16090	COG0077	Prephenate dehydratase
AL504_RS16100	COG2081	HI0933 family
AL504_RS16105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_RS16130	COG1126	abc transporter atp-binding protein
AL504_RS16135	COG0765	amino acid transport
AL504_RS16140	COG4597	amino acid ABC transporter
AL504_RS16145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS16150	COG2884	Cell division ATP-binding protein ftsE
AL504_RS16155	COG2177	Part of the ABC transporter FtsEX involved in
AL504_RS16200	COG1194	a g-specific adenine glycosylase
AL504_RS16220	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL504_RS16235	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS16250	COG0246	Mannitol dehydrogenase
AL504_RS16255	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS16260	COG1126	abc transporter atp-binding protein
AL504_RS16265	COG0765	amino acid transport
AL504_RS16275	COG1063	alcohol dehydrogenase
AL504_RS16290	COG2186	Transcriptional regulator
AL504_RS16300	COG4771	TonB-dependent receptor
AL504_RS16305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL504_RS16310	COG2022	thiamine diphosphate biosynthetic process
AL504_RS16315	COG0351	phosphomethylpyrimidine kinase
AL504_RS16320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL504_RS16330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL504_RS16340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL504_RS16355	COG2226	methyltransferase
AL504_RS16360	COG0745	RESPONSE REGULATOR receiver
AL504_RS16365	COG5002	protein histidine kinase activity
AL504_RS16385	COG2132	Multicopper oxidase
AL504_RS16400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_RS16415	COG4774	siderophore transport
AL504_RS16440	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL504_RS16445	COG1984	allophanate hydrolase subunit 2
AL504_RS16455	COG1802	Transcriptional regulator
AL504_RS16460	COG2860	membrane
AL504_RS16470	COG2223	nitrite transmembrane transporter activity
AL504_RS16475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_RS16475	COG2813	Specifically methylates the guanine in position
AL504_RS16480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_RS16485	COG2188	Transcriptional regulator
AL504_RS16490	COG2721	sulfolactate sulfo-lyase activity
AL504_RS16495	COG2721	sulfolactate sulfo-lyase activity
AL504_RS16500	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS16505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_RS16510	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_RS16540	COG2918	glutathione biosynthetic process
AL504_RS16550	COG2988	succinylglutamate desuccinylase activity
AL504_RS16560	COG0583	DNA-binding transcription factor activity
AL504_RS16570	COG1802	Transcriptional regulator
AL504_RS16585	COG1129	ABC transporter
AL504_RS16605	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS16620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS16645	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS16660	COG1309	transcriptional regulator
AL504_RS16670	COG1024	Enoyl-CoA hydratase
AL504_RS16675	COG1024	Enoyl-CoA hydratase
AL504_RS16680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL504_RS16690	COG0747	negative chemotaxis
AL504_RS16695	COG0583	DNA-binding transcription factor activity
AL504_RS16705	COG2988	succinylglutamate desuccinylase activity
AL504_RS16710	COG4166	transmembrane transport
AL504_RS16715	COG0601	transmembrane transport
AL504_RS16730	COG4608	Belongs to the ABC transporter superfamily
AL504_RS16740	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL504_RS16745	COG2171	N-acyltransferase activity
AL504_RS16755	COG4221	oxidoreductase activity
AL504_RS16760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL504_RS16775	COG0210	DNA helicase
AL504_RS16780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL504_RS16785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL504_RS16795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL504_RS16805	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL504_RS16815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL504_RS16830	COG0356	it plays a direct role in the translocation of protons across the membrane
AL504_RS16845	COG1024	Enoyl-CoA hydratase
AL504_RS16860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_RS16875	COG0583	DNA-binding transcription factor activity
AL504_RS16880	COG3473	Maleate cis-trans isomerase
AL504_RS16905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL504_RS16910	COG1131	(ABC) transporter
AL504_RS16920	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS16925	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS16945	COG0583	DNA-binding transcription factor activity
AL504_RS16950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_RS16970	COG0037	tRNA processing
AL504_RS16985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_RS16995	COG2967	ApaG domain
AL504_RS17000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL504_RS17005	COG0546	phosphoglycolate phosphatase activity
AL504_RS17015	COG0512	Glutamine amidotransferase of anthranilate synthase
AL504_RS17020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL504_RS17025	COG0134	indole-3-glycerol-phosphate synthase activity
AL504_RS17030	COG3284	Transcriptional regulator
AL504_RS17035	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS17075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS17080	COG1216	Glycosyl transferase, family 2
AL504_RS17080	COG1442	glycosyl transferase family 8
AL504_RS17090	COG3276	selenocysteine insertion sequence binding
AL504_RS17095	COG1921	L-seryl-tRNASec selenium transferase activity
AL504_RS17105	COG2864	formate dehydrogenase
AL504_RS17110	COG0437	4 iron, 4 sulfur cluster binding
AL504_RS17115	COG0243	molybdopterin cofactor binding
AL504_RS17115	COG3383	formate dehydrogenase (NAD+) activity
AL504_RS17120	COG0243	molybdopterin cofactor binding
AL504_RS17120	COG3383	formate dehydrogenase (NAD+) activity
AL504_RS17130	COG1607	acyl-coa hydrolase
AL504_RS17165	COG3585	molybdate ion transport
AL504_RS17170	COG1116	anion transmembrane transporter activity
AL504_RS17175	COG1464	Belongs to the NlpA lipoprotein family
AL504_RS17180	COG2011	ABC-type metal ion transport system permease component
AL504_RS17195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS17200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS17205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS17210	COG0431	NADPH-dependent FMN reductase
AL504_RS17215	COG1464	Belongs to the NlpA lipoprotein family
AL504_RS17240	COG0747	negative chemotaxis
AL504_RS17250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS17260	COG0589	response to stress
AL504_RS17275	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS17280	COG3069	C4-dicarboxylate transmembrane transporter activity
AL504_RS17290	COG1802	Transcriptional regulator
AL504_RS17350	COG3188	usher protein
AL504_RS17365	COG2814	Major facilitator Superfamily
AL504_RS17370	COG0840	transmembrane signaling receptor activity
AL504_RS17385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL504_RS17390	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL504_RS17400	COG2188	Transcriptional regulator
AL504_RS17460	COG0463	Glycosyl transferase, family 2
AL504_RS17465	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL504_RS17475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL504_RS17485	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL504_RS17490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL504_RS17495	COG5001	Diguanylate cyclase
AL504_RS17500	COG2423	ornithine cyclodeaminase activity
AL504_RS17505	COG0583	DNA-binding transcription factor activity
AL504_RS17510	COG2814	Major facilitator Superfamily
AL504_RS17520	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL504_RS17535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS17540	COG1120	ATPase activity
AL504_RS17550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS17555	COG4592	Periplasmic binding protein
AL504_RS17560	COG4774	siderophore transport
AL504_RS17565	COG2207	Transcriptional regulator
AL504_RS17580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS17595	COG1595	DNA-templated transcription, initiation
AL504_RS17640	COG2814	Major facilitator Superfamily
AL504_RS17645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL504_RS17665	COG1999	signal sequence binding
AL504_RS17675	COG1612	heme a metabolic process
AL504_RS17705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL504_RS17725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_RS17750	COG0070	glutamate synthase
AL504_RS17750	COG0067	glutamate synthase
AL504_RS17750	COG0069	glutamate synthase activity
AL504_RS17775	COG1984	allophanate hydrolase subunit 2
AL504_RS17790	COG0511	ligase activity, forming carbon-carbon bonds
AL504_RS17795	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL504_RS17800	COG0583	DNA-binding transcription factor activity
AL504_RS17810	COG0583	DNA-binding transcription factor activity
AL504_RS17815	COG0477	Major facilitator Superfamily
AL504_RS17825	COG2070	2-Nitropropane dioxygenase
AL504_RS17830	COG1127	ABC transporter
AL504_RS17835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL504_RS17840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL504_RS17845	COG2853	Lipoprotein
AL504_RS17855	COG1131	(ABC) transporter
AL504_RS17860	COG0842	Transport permease protein
AL504_RS17870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL504_RS17875	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL504_RS17880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL504_RS17885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL504_RS17890	COG0131	Imidazoleglycerol-phosphate dehydratase
AL504_RS17895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL504_RS17900	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL504_RS17905	COG0107	imidazoleglycerol-phosphate synthase activity
AL504_RS17915	COG0140	phosphoribosyl-ATP diphosphatase activity
AL504_RS17920	COG0537	adenosine 5'-monophosphoramidase activity
AL504_RS17925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL504_RS17930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL504_RS17950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL504_RS17955	COG1970	mechanosensitive ion channel activity
AL504_RS17960	COG0723	plastoquinol--plastocyanin reductase activity
AL504_RS17965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL504_RS17970	COG2857	Cytochrome c1
AL504_RS17975	COG0625	glutathione transferase activity
AL504_RS17980	COG2969	positive regulation of protein catabolic process
AL504_RS18040	COG5489	Protein of unknown function (DUF736)
AL504_RS18050	COG1396	sequence-specific DNA binding
AL504_RS18075	COG1192	Involved in chromosome partitioning
AL504_RS18090	COG4959	Type IV secretory pathway protease TraF
AL504_RS18110	COG1024	Enoyl-CoA hydratase
AL504_RS18115	COG0183	Belongs to the thiolase family
AL504_RS18120	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS18125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS18145	COG2814	Major facilitator Superfamily
AL504_RS18150	COG1960	acyl-CoA dehydrogenase activity
AL504_RS18155	COG2030	dehydratase
AL504_RS18170	COG0583	DNA-binding transcription factor activity
AL504_RS18190	COG4962	Type ii secretion system protein e
AL504_RS18195	COG3838	Conjugal transfer protein Trbc
AL504_RS18205	COG3451	type IV secretory pathway VirB4
AL504_RS18215	COG3846	protein secretion by the type IV secretion system
AL504_RS18265	COG0583	DNA-binding transcription factor activity
AL504_RS18275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL504_RS18285	COG3708	Transcriptional regulator
AL504_RS18285	COG2207	Transcriptional regulator
AL504_RS18295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL504_RS18300	COG0747	negative chemotaxis
AL504_RS18305	COG0601	transmembrane transport
AL504_RS18310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS18315	COG4172	Belongs to the ABC transporter superfamily
AL504_RS18320	COG1228	amidohydrolase
AL504_RS18325	COG5339	Protein conserved in bacteria
AL504_RS18330	COG5339	Protein conserved in bacteria
AL504_RS18335	COG0513	Belongs to the DEAD box helicase family
AL504_RS18340	COG1280	lysine exporter protein (LysE YggA)
AL504_RS18360	COG0697	spore germination
AL504_RS18365	COG0583	DNA-binding transcription factor activity
AL504_RS18380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL504_RS18395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS18405	COG1609	Transcriptional regulator
AL504_RS18410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_RS18420	COG1653	transport
AL504_RS18425	COG1175	transmembrane transport
AL504_RS18430	COG0395	ABC-type sugar transport system, permease component
AL504_RS18465	COG0018	arginyl-trna synthetase
AL504_RS18475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL504_RS18500	COG1280	lysine exporter protein (LysE YggA)
AL504_RS18515	COG1742	UPF0060 membrane protein
AL504_RS18530	COG1473	amidohydrolase
AL504_RS18535	COG1960	acyl-CoA dehydrogenase activity
AL504_RS18540	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AL504_RS18550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL504_RS18600	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS18615	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS18620	COG1595	DNA-templated transcription, initiation
AL504_RS18640	COG2188	Transcriptional regulator
AL504_RS18650	COG1335	isochorismatase
AL504_RS18670	COG3339	Conserved Protein
AL504_RS18680	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AL504_RS18705	COG4977	sequence-specific DNA binding
AL504_RS18725	COG1595	DNA-templated transcription, initiation
AL504_RS18730	COG3712	iron ion homeostasis
AL504_RS18740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL504_RS18745	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS18760	COG1309	transcriptional regulator
AL504_RS18765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS18770	COG0765	amino acid transport
AL504_RS18775	COG0765	amino acid transport
AL504_RS18795	COG2358	TRAP transporter, solute receptor (TAXI family
AL504_RS18805	COG2922	Belongs to the Smg family
AL504_RS18810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL504_RS18835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS18845	COG0028	Belongs to the TPP enzyme family
AL504_RS18850	COG1522	sequence-specific DNA binding
AL504_RS18855	COG3781	membrane
AL504_RS18870	COG2814	Major facilitator Superfamily
AL504_RS18885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS18900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL504_RS18910	COG1744	ABC transporter substrate-binding protein PnrA-like
AL504_RS18915	COG3845	ABC transporter
AL504_RS18920	COG4603	Belongs to the binding-protein-dependent transport system permease family
AL504_RS18930	COG0402	S-adenosylhomocysteine deaminase activity
AL504_RS18940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS18945	COG0583	DNA-binding transcription factor activity
AL504_RS18950	COG0251	oxidation-reduction process
AL504_RS18975	COG1177	transmembrane transport
AL504_RS18980	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_RS18985	COG3842	ATPase activity
AL504_RS18995	COG1609	Transcriptional regulator
AL504_RS19050	COG1177	transmembrane transport
AL504_RS19055	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_RS19100	COG1126	abc transporter atp-binding protein
AL504_RS19105	COG0765	amino acid transport
AL504_RS19110	COG0765	amino acid transport
AL504_RS19115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS19120	COG0583	DNA-binding transcription factor activity
AL504_RS19130	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL504_RS19140	COG1741	Belongs to the pirin family
AL504_RS19155	COG0583	DNA-binding transcription factor activity
AL504_RS19165	COG0592	DNA-directed DNA polymerase activity
AL504_RS19170	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL504_RS19175	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL504_RS19180	COG0594	ribonuclease P activity
AL504_RS19190	COG0753	catalase activity
AL504_RS19195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL504_RS19205	COG3712	iron ion homeostasis
AL504_RS19215	COG2175	clavaminate synthase activity
AL504_RS19220	COG1473	amidohydrolase
AL504_RS19225	COG4608	Belongs to the ABC transporter superfamily
AL504_RS19230	COG0444	Belongs to the ABC transporter superfamily
AL504_RS19235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS19240	COG0601	transmembrane transport
AL504_RS19250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL504_RS19260	COG0038	chloride channel
AL504_RS19290	COG0436	Aminotransferase
AL504_RS19295	COG3180	Ammonia monooxygenase
AL504_RS19300	COG1278	Cold shock
AL504_RS19305	COG0445	tRNA wobble uridine modification
AL504_RS19310	COG0357	Ribosomal RNA small subunit methyltransferase G
AL504_RS19315	COG1192	Involved in chromosome partitioning
AL504_RS19325	COG1475	DNA binding
AL504_RS19330	COG0252	asparaginase activity
AL504_RS19335	COG0583	DNA-binding transcription factor activity
AL504_RS19360	COG1349	DNA-binding transcription factor activity
AL504_RS19370	COG3842	ATPase activity
AL504_RS19375	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_RS19415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL504_RS19425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL504_RS19435	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL504_RS19440	COG0081	regulation of translation
AL504_RS19445	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL504_RS19450	COG0222	ribosome binding
AL504_RS19455	COG0085	RNA polymerase activity
AL504_RS19460	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL504_RS19475	COG5002	protein histidine kinase activity
AL504_RS19490	COG0745	RESPONSE REGULATOR receiver
AL504_RS19495	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL504_RS19500	COG0049	tRNA binding
AL504_RS19505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL504_RS19510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL504_RS19515	COG0051	transcription antitermination factor activity, RNA binding
AL504_RS19520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL504_RS19530	COG0089	rRNA binding
AL504_RS19535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL504_RS19540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL504_RS19545	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL504_RS19550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL504_RS19555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL504_RS19560	COG0255	Belongs to the universal ribosomal protein uL29 family
AL504_RS19565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL504_RS19580	COG3307	-O-antigen
AL504_RS19590	COG1215	transferase activity, transferring glycosyl groups
AL504_RS19605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL504_RS19645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL504_RS19665	COG0455	bacterial-type flagellum organization
AL504_RS19670	COG1215	transferase activity, transferring glycosyl groups
AL504_RS19675	COG1215	transferase activity, transferring glycosyl groups
AL504_RS19680	COG1215	transferase activity, transferring glycosyl groups
AL504_RS19685	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AL504_RS19690	COG0457	Tetratricopeptide repeat
AL504_RS19725	COG4177	L-phenylalanine transmembrane transporter activity
AL504_RS19750	COG2207	Transcriptional regulator
AL504_RS19770	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL504_RS19775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL504_RS19780	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL504_RS19785	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL504_RS19790	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL504_RS19795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL504_RS19800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL504_RS19805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL504_RS19810	COG1841	ribosomal large subunit assembly
AL504_RS19815	COG0200	Binds to the 23S rRNA
AL504_RS19820	COG0201	protein transport
AL504_RS19825	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL504_RS19830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL504_RS19835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL504_RS19840	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL504_RS19845	COG0202	RNA polymerase activity
AL504_RS19850	COG0203	ribosomal protein L17
AL504_RS19860	COG1324	tolerance protein
AL504_RS19865	COG4232	protein-disulfide reductase activity
AL504_RS19880	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL504_RS19895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL504_RS19905	COG1965	Belongs to the frataxin family
AL504_RS19915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL504_RS19920	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL504_RS19925	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL504_RS19930	COG0625	glutathione transferase activity
AL504_RS19940	COG2814	Major facilitator Superfamily
AL504_RS19950	COG2226	methyltransferase
AL504_RS19985	COG2186	Transcriptional regulator
AL504_RS20010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS20015	COG1956	GAF domain-containing protein
AL504_RS20020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS20035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL504_RS20060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL504_RS20065	COG3568	Endonuclease Exonuclease Phosphatase
AL504_RS20070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS20080	COG2814	Major facilitator Superfamily
AL504_RS20110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL504_RS20145	COG1134	teichoic acid transport
AL504_RS20155	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS20160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL504_RS20170	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL504_RS20180	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL504_RS20190	COG2089	acid synthase
AL504_RS20195	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL504_RS20200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL504_RS20205	COG1088	dTDP-glucose 4,6-dehydratase activity
AL504_RS20230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL504_RS20235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL504_RS20255	COG0673	inositol 2-dehydrogenase activity
AL504_RS20260	COG0859	PFAM glycosyl transferase family 9
AL504_RS20270	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AL504_RS20280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL504_RS20305	COG1686	Belongs to the peptidase S11 family
AL504_RS20315	COG2921	Belongs to the UPF0250 family
AL504_RS20320	COG0321	lipoyl(octanoyl) transferase activity
AL504_RS20335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL504_RS20340	COG2096	Adenosyltransferase
AL504_RS20350	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL504_RS20355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL504_RS20365	COG0523	cobalamin synthesis protein
AL504_RS20370	COG0735	belongs to the Fur family
AL504_RS20385	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL504_RS20400	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL504_RS20410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL504_RS20415	COG1560	Kdo2-lipid A biosynthetic process
AL504_RS20425	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL504_RS20430	COG0154	amidase activity
AL504_RS20435	COG0477	Major facilitator Superfamily
AL504_RS20445	COG0583	DNA-binding transcription factor activity
AL504_RS20450	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS20460	COG0066	3-isopropylmalate dehydratase activity
AL504_RS20475	COG0438	transferase activity, transferring glycosyl groups
AL504_RS20480	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL504_RS20485	COG1950	PFAM Membrane protein of
AL504_RS20505	COG1305	Transglutaminase-like
AL504_RS20515	COG2308	Evidence 4 Homologs of previously reported genes of
AL504_RS20540	COG0513	Belongs to the DEAD box helicase family
AL504_RS20545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL504_RS20555	COG3210	domain, Protein
AL504_RS20555	COG3210	domain, Protein
AL504_RS20565	COG0351	phosphomethylpyrimidine kinase
AL504_RS20565	COG0352	thiamine-phosphate diphosphorylase activity
AL504_RS20565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL504_RS20580	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS20600	COG3189	MarR family transcriptional regulator
AL504_RS20630	COG0640	Transcriptional regulator
AL504_RS20690	COG1846	Transcriptional regulator
AL504_RS20695	COG1764	response to oxidative stress
AL504_RS20725	COG0583	DNA-binding transcription factor activity
AL504_RS20740	COG0583	DNA-binding transcription factor activity
AL504_RS20750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL504_RS20755	COG0708	Exodeoxyribonuclease III
AL504_RS20760	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL504_RS20770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL504_RS20775	COG0154	amidase activity
AL504_RS20780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL504_RS20785	COG1077	Cell shape determining protein MreB Mrl
AL504_RS20790	COG1792	Involved in formation and maintenance of cell shape
AL504_RS20800	COG0768	penicillin binding
AL504_RS20805	COG0772	Belongs to the SEDS family
AL504_RS20815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_RS20820	COG0471	metal ion transport
AL504_RS20825	COG1309	transcriptional regulator
AL504_RS20835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL504_RS20845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS20855	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL504_RS20860	COG0792	nuclease activity
AL504_RS20870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL504_RS20880	COG1660	Displays ATPase and GTPase activities
AL504_RS20895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS20900	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AL504_RS20910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL504_RS20915	COG1137	ATPase activity
AL504_RS20940	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL504_RS20955	COG1294	oxidase, subunit
AL504_RS20960	COG4988	ABC transporter
AL504_RS20965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL504_RS20970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL504_RS20985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS20990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL504_RS20995	COG1238	metal cluster binding
AL504_RS21010	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS21015	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL504_RS21020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS21025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS21040	COG0758	DNA mediated transformation
AL504_RS21045	COG0242	peptide deformylase activity
AL504_RS21050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL504_RS21060	COG0546	phosphoglycolate phosphatase activity
AL504_RS21080	COG1733	regulation of RNA biosynthetic process
AL504_RS21090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL504_RS21095	COG1280	lysine exporter protein (LysE YggA)
AL504_RS21100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL504_RS21100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL504_RS21110	COG5000	phosphorelay sensor kinase activity
AL504_RS21115	COG2204	response regulator
AL504_RS21120	COG0569	domain protein
AL504_RS21125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL504_RS21130	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AL504_RS21135	COG2226	methyltransferase
AL504_RS21150	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS21155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL504_RS21160	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL504_RS21165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL504_RS21170	COG1054	Belongs to the UPF0176 family
AL504_RS21175	COG0588	phosphoglycerate mutase activity
AL504_RS21180	COG4942	peptidase
AL504_RS21185	COG0793	Belongs to the peptidase S41A family
AL504_RS21190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL504_RS21195	COG3300	MHYT domain
AL504_RS21195	COG5001	Diguanylate cyclase
AL504_RS21200	COG2186	Transcriptional regulator
AL504_RS21215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_RS21215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_RS21230	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL504_RS21235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL504_RS21240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL504_RS21245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL504_RS21250	COG0142	geranyltranstransferase activity
AL504_RS21275	COG2986	histidine ammonia-lyase
AL504_RS21340	COG0235	Class ii aldolase
AL504_RS21345	COG3622	Belongs to the hyi family
AL504_RS21350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS21355	COG2084	Dehydrogenase
AL504_RS21360	COG3395	kinase activity
AL504_RS21365	COG2186	Transcriptional regulator
AL504_RS21390	COG3622	Belongs to the hyi family
AL504_RS21410	COG1522	sequence-specific DNA binding
AL504_RS21415	COG1280	lysine exporter protein (LysE YggA)
AL504_RS21430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL504_RS21435	COG2890	protein-(glutamine-N5) methyltransferase activity
AL504_RS21440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL504_RS21455	COG1464	Belongs to the NlpA lipoprotein family
AL504_RS21475	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS21500	COG0477	Major facilitator Superfamily
AL504_RS21515	COG0583	DNA-binding transcription factor activity
AL504_RS21530	COG0625	glutathione transferase activity
AL504_RS21535	COG1053	succinate dehydrogenase
AL504_RS21545	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS21565	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS21575	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS21580	COG1802	Transcriptional regulator
AL504_RS21585	COG0288	reversible hydration of carbon dioxide
AL504_RS21605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_RS21615	COG4829	muconolactone delta-isomerase
AL504_RS21620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_RS21630	COG1414	Transcriptional regulator
AL504_RS21635	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS21640	COG2031	fatty acid transporter
AL504_RS21645	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS21650	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL504_RS21655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL504_RS21675	COG0583	DNA-binding transcription factor activity
AL504_RS21680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS21695	COG0129	dihydroxy-acid dehydratase activity
AL504_RS21700	COG0583	DNA-binding transcription factor activity
AL504_RS21705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL504_RS21710	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL504_RS21720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL504_RS21725	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS21730	COG0410	ABC transporter
AL504_RS21765	COG2186	Transcriptional regulator
AL504_RS21775	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AL504_RS21800	COG0583	DNA-binding transcription factor activity
AL504_RS21805	COG0628	permease
AL504_RS21815	COG0477	Major facilitator Superfamily
AL504_RS21830	COG1695	Transcriptional regulator
AL504_RS21840	COG0583	DNA-binding transcription factor activity
AL504_RS21985	COG0583	DNA-binding transcription factor activity
AL504_RS21990	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS22000	COG3246	L-lysine catabolic process to acetate
AL504_RS22005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL504_RS22010	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL504_RS22030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS22035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS22060	COG2233	PERMEase
AL504_RS22070	COG0326	Molecular chaperone. Has ATPase activity
AL504_RS22075	COG1396	sequence-specific DNA binding
AL504_RS22080	COG3550	peptidyl-serine autophosphorylation
AL504_RS22085	COG2814	Major facilitator Superfamily
AL504_RS22090	COG4774	siderophore transport
AL504_RS22105	COG1131	(ABC) transporter
AL504_RS22110	COG2271	Major facilitator Superfamily
AL504_RS22115	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS22120	COG0800	Aldolase
AL504_RS22130	COG1414	Transcriptional regulator
AL504_RS22150	COG3550	peptidyl-serine autophosphorylation
AL504_RS22180	COG0583	DNA-binding transcription factor activity
AL504_RS22185	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS22205	COG0625	glutathione transferase activity
AL504_RS22220	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL504_RS22225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL504_RS22230	COG1652	LysM domain
AL504_RS22255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL504_RS22260	COG0583	DNA-binding transcription factor activity
AL504_RS22265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS22270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS22300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL504_RS22320	COG3246	L-lysine catabolic process to acetate
AL504_RS22325	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS22335	COG0477	Major facilitator Superfamily
AL504_RS22365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_RS22380	COG2205	protein histidine kinase activity
AL504_RS22400	COG0165	Argininosuccinate lyase
AL504_RS22410	COG2828	Protein conserved in bacteria
AL504_RS22425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL504_RS22435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL504_RS22475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL504_RS22490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL504_RS22500	COG1234	tRNA 3'-trailer cleavage
AL504_RS22510	COG0625	glutathione transferase activity
AL504_RS22520	COG3258	Cytochrome c
AL504_RS22555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS22560	COG1294	oxidase, subunit
AL504_RS22565	COG1271	oxidase subunit
AL504_RS22570	COG1942	4-Oxalocrotonate Tautomerase
AL504_RS22575	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS22585	COG0697	spore germination
AL504_RS22590	COG0583	DNA-binding transcription factor activity
AL504_RS22595	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS22605	COG0842	Transport permease protein
AL504_RS22615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS22635	COG4774	siderophore transport
AL504_RS22645	COG1595	DNA-templated transcription, initiation
AL504_RS22675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL504_RS22680	COG0745	RESPONSE REGULATOR receiver
AL504_RS22690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL504_RS22690	COG2755	lipolytic protein G-D-S-L family
AL504_RS22705	COG1054	Belongs to the UPF0176 family
AL504_RS22710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_RS22710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_RS22720	COG0489	protein tyrosine kinase activity
AL504_RS22735	COG0717	Belongs to the dCTP deaminase family
AL504_RS22745	COG3706	GGDEF domain
AL504_RS22765	COG2081	HI0933 family
AL504_RS22780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL504_RS22785	COG0509	glycine decarboxylation via glycine cleavage system
AL504_RS22790	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL504_RS22790	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL504_RS22805	COG0154	amidase activity
AL504_RS22810	COG4172	Belongs to the ABC transporter superfamily
AL504_RS22815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS22820	COG0601	transmembrane transport
AL504_RS22840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL504_RS22845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS22875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL504_RS22880	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL504_RS22895	COG0438	transferase activity, transferring glycosyl groups
AL504_RS22905	COG0438	transferase activity, transferring glycosyl groups
AL504_RS22915	COG0438	transferase activity, transferring glycosyl groups
AL504_RS22920	COG0405	Gamma-glutamyltransferase
AL504_RS22925	COG0166	Belongs to the GPI family
AL504_RS22940	COG0277	FAD linked oxidase domain protein
AL504_RS22945	COG0745	RESPONSE REGULATOR receiver
AL504_RS22950	COG2205	protein histidine kinase activity
AL504_RS22960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS22960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL504_RS22970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS22975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS22980	COG2186	Transcriptional regulator
AL504_RS22985	COG1368	sulfuric ester hydrolase activity
AL504_RS22990	COG0204	Acyl-transferase
AL504_RS23025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL504_RS23040	COG0840	transmembrane signaling receptor activity
AL504_RS23045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL504_RS23065	COG0193	aminoacyl-tRNA hydrolase activity
AL504_RS23075	COG0012	GTP binding
AL504_RS23080	COG4804	nuclease activity
AL504_RS23090	COG0488	(ABC) transporter
AL504_RS23105	COG2814	Major facilitator Superfamily
AL504_RS23120	COG3135	benzoate transporter
AL504_RS23125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL504_RS23130	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL504_RS23135	COG0742	ribosomal rna small subunit methyltransferase
AL504_RS23160	COG3639	organic phosphonate transmembrane transporter activity
AL504_RS23165	COG3639	organic phosphonate transmembrane transporter activity
AL504_RS23170	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL504_RS23195	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL504_RS23200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL504_RS23215	COG1546	Belongs to the CinA family
AL504_RS23215	COG1058	Belongs to the CinA family
AL504_RS23220	COG0284	orotidine-5'-phosphate decarboxylase activity
AL504_RS23225	COG1252	NADH dehydrogenase
AL504_RS23230	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL504_RS23235	COG0246	Mannitol dehydrogenase
AL504_RS23245	COG1137	ATPase activity
AL504_RS23270	COG1917	Cupin 2, conserved barrel domain protein
AL504_RS23290	COG4774	siderophore transport
AL504_RS23305	COG1846	Transcriptional regulator
AL504_RS23315	COG0459	protein refolding
AL504_RS23320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL504_RS23355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS23380	COG0372	Belongs to the citrate synthase family
AL504_RS23395	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS23400	COG2207	Transcriptional regulator
AL504_RS23410	COG0583	DNA-binding transcription factor activity
AL504_RS23425	COG0243	molybdopterin cofactor binding
AL504_RS23430	COG0038	chloride channel
AL504_RS23435	COG4191	Histidine kinase
AL504_RS23460	COG2200	EAL domain
AL504_RS23465	COG0300	oxidoreductase activity
AL504_RS23480	COG2375	cellular response to nickel ion
AL504_RS23480	COG1132	(ABC) transporter
AL504_RS23485	COG1132	(ABC) transporter
AL504_RS23490	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS23495	COG4605	iron ion homeostasis
AL504_RS23500	COG4604	ABC transporter, ATP-binding protein
AL504_RS23505	COG4607	ABC-type enterochelin transport system periplasmic component
AL504_RS23510	COG4774	siderophore transport
AL504_RS23535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_RS23560	COG0657	acetylesterase activity
AL504_RS23580	COG0384	phenazine biosynthesis protein PhzF
AL504_RS23605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL504_RS23615	COG0745	RESPONSE REGULATOR receiver
AL504_RS23645	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS23660	COG0277	FAD linked oxidase domain protein
AL504_RS23675	COG0793	Belongs to the peptidase S41A family
AL504_RS23690	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS23695	COG2267	carboxylic ester hydrolase activity
AL504_RS23705	COG0583	DNA-binding transcription factor activity
AL504_RS23720	COG0154	amidase activity
AL504_RS23730	COG1595	DNA-templated transcription, initiation
AL504_RS23745	COG4772	TonB-dependent receptor
AL504_RS23750	COG3712	iron ion homeostasis
AL504_RS23755	COG1595	DNA-templated transcription, initiation
AL504_RS23775	COG0583	DNA-binding transcription factor activity
AL504_RS23780	COG0583	DNA-binding transcription factor activity
AL504_RS23785	COG0436	Aminotransferase
AL504_RS23795	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS23805	COG0697	spore germination
AL504_RS23810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS23820	COG1960	acyl-CoA dehydrogenase activity
AL504_RS23825	COG0583	DNA-binding transcription factor activity
AL504_RS23830	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS23835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS23855	COG2814	Major facilitator Superfamily
AL504_RS23890	COG0431	NADPH-dependent FMN reductase
AL504_RS23930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS23985	COG4172	Belongs to the ABC transporter superfamily
AL504_RS23990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL504_RS23990	COG1793	dna ligase
AL504_RS23995	COG1793	dna ligase
AL504_RS24000	COG1201	RNA secondary structure unwinding
AL504_RS24010	COG1132	(ABC) transporter
AL504_RS24025	COG4771	TonB-dependent receptor
AL504_RS24065	COG3712	iron ion homeostasis
AL504_RS24075	COG0028	Belongs to the TPP enzyme family
AL504_RS24095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_RS24130	COG0583	DNA-binding transcription factor activity
AL504_RS24135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_RS24145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL504_RS24160	COG0596	Alpha beta hydrolase
AL504_RS24170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS24195	COG0740	serine-type endopeptidase activity
AL504_RS24205	COG0640	Transcriptional regulator
AL504_RS24210	COG2203	Gaf domain
AL504_RS24210	COG2199	diguanylate cyclase activity
AL504_RS24215	COG0840	transmembrane signaling receptor activity
AL504_RS24240	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS24245	COG0583	DNA-binding transcription factor activity
AL504_RS24250	COG0456	acetyltransferase
AL504_RS24260	COG0023	Translation Initiation Factor
AL504_RS24265	COG0583	DNA-binding transcription factor activity
AL504_RS24270	COG0656	L-ascorbic acid biosynthetic process
AL504_RS24280	COG0667	Aldo Keto reductase
AL504_RS24290	COG0243	molybdopterin cofactor binding
AL504_RS24295	COG2146	nitrite reductase [NAD(P)H] activity
AL504_RS24295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL504_RS24300	COG2146	nitrite reductase [NAD(P)H] activity
AL504_RS24300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL504_RS24305	COG3707	response regulator
AL504_RS24330	COG2197	response regulator
AL504_RS24355	COG0625	glutathione transferase activity
AL504_RS24380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS24385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS24395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL504_RS24400	COG1845	cytochrome c oxidase, subunit III
AL504_RS24405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL504_RS24410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL504_RS24415	COG0477	Major facilitator Superfamily
AL504_RS24425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS24430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_RS24470	COG0583	DNA-binding transcription factor activity
AL504_RS24485	COG4106	trans-aconitate 2-methyltransferase activity
AL504_RS24490	COG2207	Transcriptional regulator
AL504_RS24495	COG2807	transmembrane transport
AL504_RS24520	COG0330	HflC and HflK could
AL504_RS24525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL504_RS24540	COG3712	iron ion homeostasis
AL504_RS24550	COG4221	oxidoreductase activity
AL504_RS24565	COG3712	iron ion homeostasis
AL504_RS24575	COG1595	DNA-templated transcription, initiation
AL504_RS24580	COG3712	iron ion homeostasis
AL504_RS24595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL504_RS24610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL504_RS24615	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS24620	COG1285	pathogenesis
AL504_RS24625	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL504_RS24640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL504_RS24665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS24670	COG1396	sequence-specific DNA binding
AL504_RS24690	COG0583	DNA-binding transcription factor activity
AL504_RS24725	COG0697	spore germination
AL504_RS24730	COG1917	Cupin 2, conserved barrel domain protein
AL504_RS24730	COG2207	Transcriptional regulator
AL504_RS24740	COG0280	phosphate acetyltransferase
AL504_RS24740	COG0281	malic enzyme
AL504_RS24760	COG4772	TonB-dependent receptor
AL504_RS24775	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL504_RS24780	COG1845	cytochrome c oxidase, subunit III
AL504_RS24785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL504_RS24795	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AL504_RS24815	COG1999	signal sequence binding
AL504_RS24840	COG1126	abc transporter atp-binding protein
AL504_RS24845	COG0765	amino acid transport
AL504_RS24850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS24855	COG3191	aminopeptidase activity
AL504_RS24860	COG1272	protein, Hemolysin III
AL504_RS24865	COG1522	sequence-specific DNA binding
AL504_RS24875	COG1113	amino acid transport
AL504_RS24880	COG0583	DNA-binding transcription factor activity
AL504_RS24905	COG2378	regulation of single-species biofilm formation
AL504_RS24935	COG1595	DNA-templated transcription, initiation
AL504_RS24940	COG3712	iron ion homeostasis
AL504_RS24950	COG3720	iron ion transport
AL504_RS24955	COG4558	Periplasmic binding protein
AL504_RS24960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS24965	COG1120	ATPase activity
AL504_RS24970	COG1666	GTP binding
AL504_RS24985	COG0671	phosphoesterase, PA-phosphatase related
AL504_RS25015	COG4774	siderophore transport
AL504_RS25080	COG0456	acetyltransferase
AL504_RS25085	COG0583	DNA-binding transcription factor activity
AL504_RS25090	COG2828	Protein conserved in bacteria
AL504_RS25110	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS25160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL504_RS25165	COG0583	DNA-binding transcription factor activity
AL504_RS25190	COG2223	nitrite transmembrane transporter activity
AL504_RS25200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL504_RS25205	COG3383	formate dehydrogenase (NAD+) activity
AL504_RS25225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL504_RS25230	COG0746	molybdenum cofactor guanylyltransferase activity
AL504_RS25240	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL504_RS25245	COG0314	molybdopterin synthase activity
AL504_RS25255	COG0315	cyclic pyranopterin monophosphate synthase activity
AL504_RS25265	COG0412	Dienelactone hydrolase
AL504_RS25275	COG0678	peroxiredoxin activity
AL504_RS25285	COG0697	spore germination
AL504_RS25330	COG0667	Aldo Keto reductase
AL504_RS25335	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL504_RS25340	COG4535	Mg2 and Co2 transporter CorC
AL504_RS25345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL504_RS25350	COG1702	phosphate starvation-inducible protein PhoH
AL504_RS25355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL504_RS25365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL504_RS25385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_RS25390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_RS25395	COG1862	Preprotein translocase
AL504_RS25400	COG3077	Addiction module antitoxin, RelB DinJ family
AL504_RS25410	COG0343	queuine tRNA-ribosyltransferase activity
AL504_RS25415	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL504_RS25425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS25440	COG2027	D-alanyl-D-alanine carboxypeptidase
AL504_RS25445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL504_RS25450	COG1648	precorrin-2 dehydrogenase activity
AL504_RS25450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL504_RS25455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS25460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS25465	COG1116	anion transmembrane transporter activity
AL504_RS25475	COG4575	ribosome binding
AL504_RS25490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL504_RS25495	COG0741	lytic transglycosylase activity
AL504_RS25505	COG0436	Aminotransferase
AL504_RS25515	COG0281	malic enzyme
AL504_RS25515	COG0280	phosphate acetyltransferase
AL504_RS25525	COG2732	(Barnase) inhibitor
AL504_RS25530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL504_RS25545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL504_RS25550	COG0126	phosphoglycerate kinase activity
AL504_RS25565	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL504_RS25570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL504_RS25590	COG0625	glutathione transferase activity
AL504_RS25610	COG0789	Transcriptional regulator
AL504_RS25625	COG0306	phosphate transporter
AL504_RS25635	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL504_RS25645	COG0739	heme binding
AL504_RS25655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL504_RS25665	COG0640	Transcriptional regulator
AL504_RS25675	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL504_RS25680	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL504_RS25685	COG3639	organic phosphonate transmembrane transporter activity
AL504_RS25705	COG0583	DNA-binding transcription factor activity
AL504_RS25710	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL504_RS25715	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL504_RS25720	COG3454	Phosphonate metabolism
AL504_RS25725	COG2188	Transcriptional regulator
AL504_RS25730	COG3624	Phosphonate C-P lyase system protein PhnG
AL504_RS25735	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL504_RS25740	COG3626	phosphonate metabolism
AL504_RS25745	COG3627	carbon phosphorus lyase activity
AL504_RS25750	COG4107	phosphonate C-P lyase system protein PhnK
AL504_RS25755	COG4778	phosphonate C-P lyase system protein PhnL
AL504_RS25760	COG3454	Phosphonate metabolism
AL504_RS25775	COG1301	dicarboxylic acid transport
AL504_RS25795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL504_RS25800	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL504_RS25805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL504_RS25810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL504_RS25815	COG0009	L-threonylcarbamoyladenylate synthase
AL504_RS25820	COG1414	Transcriptional regulator
AL504_RS25825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_RS25840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS25845	COG1414	Transcriptional regulator
AL504_RS25850	COG0010	Belongs to the arginase family
AL504_RS25860	COG0765	amino acid transport
AL504_RS25865	COG1126	abc transporter atp-binding protein
AL504_RS25870	COG0028	Belongs to the TPP enzyme family
AL504_RS25885	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS25915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL504_RS25935	COG2030	dehydratase
AL504_RS25960	COG0028	Belongs to the TPP enzyme family
AL504_RS25965	COG0583	DNA-binding transcription factor activity
AL504_RS25970	COG4974	Belongs to the 'phage' integrase family
AL504_RS25975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL504_RS25995	COG1686	Belongs to the peptidase S11 family
AL504_RS26010	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS26015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS26025	COG1024	Enoyl-CoA hydratase
AL504_RS26030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS26045	COG2070	2-Nitropropane dioxygenase
AL504_RS26060	COG1074	ATP-dependent DNA helicase activity
AL504_RS26085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL504_RS26100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS26105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS26115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS26130	COG0745	RESPONSE REGULATOR receiver
AL504_RS26150	COG0505	Belongs to the CarA family
AL504_RS26155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL504_RS26170	COG0406	alpha-ribazole phosphatase activity
AL504_RS26180	COG3842	ATPase activity
AL504_RS26200	COG2233	PERMEase
AL504_RS26205	COG0840	transmembrane signaling receptor activity
AL504_RS26210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL504_RS26215	COG1534	Rna-binding protein
AL504_RS26220	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL504_RS26225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL504_RS26235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL504_RS26270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL504_RS26275	COG2814	Major facilitator Superfamily
AL504_RS26285	COG0477	Major facilitator Superfamily
AL504_RS26290	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS26305	COG2841	Protein conserved in bacteria
AL504_RS26320	COG1595	DNA-templated transcription, initiation
AL504_RS26330	COG0583	DNA-binding transcription factor activity
AL504_RS26335	COG2207	Transcriptional regulator
AL504_RS26340	COG0667	Aldo Keto reductase
AL504_RS26365	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL504_RS26370	COG0500	methyltransferase
AL504_RS26400	COG0517	IMP dehydrogenase activity
AL504_RS26410	COG3938	Belongs to the proline racemase family
AL504_RS26415	COG1177	transmembrane transport
AL504_RS26425	COG3842	ATPase activity
AL504_RS26485	COG1511	domain protein
AL504_RS26485	COG3264	Mechanosensitive ion channel
AL504_RS26490	COG0583	DNA-binding transcription factor activity
AL504_RS26495	COG0427	acetyl-CoA hydrolase
AL504_RS26500	COG0583	DNA-binding transcription factor activity
AL504_RS26540	COG0235	Class ii aldolase
AL504_RS26550	COG0583	DNA-binding transcription factor activity
AL504_RS26565	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS26575	COG0477	Major facilitator Superfamily
AL504_RS26585	COG0154	amidase activity
AL504_RS26605	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL504_RS26620	COG0495	leucyl-tRNA aminoacylation
AL504_RS26625	COG2814	Major facilitator Superfamily
AL504_RS26630	COG1846	Transcriptional regulator
AL504_RS26640	COG1686	Belongs to the peptidase S11 family
AL504_RS26675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL504_RS26680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL504_RS26685	COG2814	Major facilitator Superfamily
AL504_RS26690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_RS26700	COG4176	ABC-type proline glycine betaine transport system permease component
AL504_RS26720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS26725	COG2706	6-phosphogluconolactonase activity
AL504_RS26730	COG4214	carbohydrate transport
AL504_RS26735	COG1129	ABC transporter
AL504_RS26740	COG4213	ABC transporter substrate-binding protein
AL504_RS26750	COG0183	Belongs to the thiolase family
AL504_RS26760	COG1802	Transcriptional regulator
AL504_RS26770	COG1024	Enoyl-CoA hydratase
AL504_RS26775	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS26785	COG0667	Aldo Keto reductase
AL504_RS26795	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL504_RS26810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS26820	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL504_RS26840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AL504_RS26845	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL504_RS26850	COG4149	molybdate abc transporter
AL504_RS26855	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL504_RS26880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS26885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS26895	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL504_RS26900	COG0736	holo-[acyl-carrier-protein] synthase activity
AL504_RS26915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL504_RS26925	COG0473	3-isopropylmalate dehydrogenase activity
AL504_RS26930	COG0583	DNA-binding transcription factor activity
AL504_RS26935	COG1858	cytochrome C peroxidase
AL504_RS26940	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL504_RS26940	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL504_RS26945	COG2224	Isocitrate lyase
AL504_RS26960	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL504_RS26960	COG4106	trans-aconitate 2-methyltransferase activity
AL504_RS26970	COG0156	8-amino-7-oxononanoate synthase activity
AL504_RS26990	COG3278	Belongs to the heme-copper respiratory oxidase family
AL504_RS27010	COG0348	domain, Protein
AL504_RS27030	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS27035	COG1126	abc transporter atp-binding protein
AL504_RS27040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS27050	COG0765	amino acid transport
AL504_RS27055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS27090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL504_RS27100	COG0438	transferase activity, transferring glycosyl groups
AL504_RS27115	COG1538	Outer membrane efflux protein
AL504_RS27120	COG1566	PFAM secretion protein HlyD family protein
AL504_RS27135	COG0583	DNA-binding transcription factor activity
AL504_RS27140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS27145	COG0586	Pfam SNARE associated Golgi protein
AL504_RS27150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS27165	COG4608	Belongs to the ABC transporter superfamily
AL504_RS27170	COG0444	Belongs to the ABC transporter superfamily
AL504_RS27175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS27180	COG0601	transmembrane transport
AL504_RS27185	COG0583	DNA-binding transcription factor activity
AL504_RS27190	COG0300	oxidoreductase activity
AL504_RS27195	COG1764	response to oxidative stress
AL504_RS27200	COG2205	protein histidine kinase activity
AL504_RS27225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_RS27240	COG1802	Transcriptional regulator
AL504_RS27255	COG1595	DNA-templated transcription, initiation
AL504_RS27275	COG2084	Dehydrogenase
AL504_RS27285	COG1917	Cupin 2, conserved barrel domain protein
AL504_RS27285	COG2207	Transcriptional regulator
AL504_RS27295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS27360	COG1280	lysine exporter protein (LysE YggA)
AL504_RS27370	COG0745	RESPONSE REGULATOR receiver
AL504_RS27385	COG4774	siderophore transport
AL504_RS27390	COG3712	iron ion homeostasis
AL504_RS27395	COG1595	DNA-templated transcription, initiation
AL504_RS27405	COG3121	Chaperone
AL504_RS27410	COG3188	usher protein
AL504_RS27430	COG0642	Histidine kinase
AL504_RS27435	COG1475	DNA binding
AL504_RS27440	COG3969	phosphoadenosine phosphosulfate
AL504_RS27445	COG1971	Probably functions as a manganese efflux pump
AL504_RS27450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_RS27510	COG0009	L-threonylcarbamoyladenylate synthase
AL504_RS27515	COG1994	Peptidase M50
AL504_RS27520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS27525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL504_RS27535	COG2850	peptidyl-arginine hydroxylation
AL504_RS27540	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL504_RS27575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL504_RS27585	COG0583	DNA-binding transcription factor activity
AL504_RS27610	COG2311	Membrane
AL504_RS27630	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS27635	COG0583	DNA-binding transcription factor activity
AL504_RS27645	COG3360	Dodecin
AL504_RS27680	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_RS27685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS27690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS27730	COG0668	transmembrane transport
AL504_RS27750	COG0583	DNA-binding transcription factor activity
AL504_RS27770	COG0483	inositol monophosphate 1-phosphatase activity
AL504_RS27775	COG4804	nuclease activity
AL504_RS27780	COG1477	protein flavinylation
AL504_RS27790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AL504_RS27805	COG4263	nitrous-oxide reductase activity
AL504_RS27820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL504_RS27825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL504_RS27835	COG1253	flavin adenine dinucleotide binding
AL504_RS27840	COG1968	undecaprenyl-diphosphatase activity
AL504_RS27845	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL504_RS27860	COG0215	cysteine-tRNA ligase activity
AL504_RS27870	COG0825	malonyl-CoA metabolic process
AL504_RS27880	COG0527	aspartate kinase activity
AL504_RS27895	COG0348	domain, Protein
AL504_RS27915	COG3278	Belongs to the heme-copper respiratory oxidase family
AL504_RS27930	COG3258	Cytochrome c
AL504_RS27935	COG2863	cytochrome
AL504_RS27940	COG2205	protein histidine kinase activity
AL504_RS27940	COG0784	Response regulator, receiver
AL504_RS27945	COG2200	EAL domain
AL504_RS27950	COG2205	protein histidine kinase activity
AL504_RS27950	COG0784	Response regulator, receiver
AL504_RS27955	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AL504_RS27965	COG1309	transcriptional regulator
AL504_RS27970	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL504_RS28010	COG0583	DNA-binding transcription factor activity
AL504_RS28035	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL504_RS28045	COG1414	Transcriptional regulator
AL504_RS28055	COG1024	Enoyl-CoA hydratase
AL504_RS28060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL504_RS28065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_RS28075	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL504_RS28090	COG1132	(ABC) transporter
AL504_RS28100	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS28110	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS28125	COG0183	Belongs to the thiolase family
AL504_RS28130	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS28130	COG1024	Enoyl-CoA hydratase
AL504_RS28140	COG1024	Enoyl-CoA hydratase
AL504_RS28140	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS28150	COG1960	acyl-CoA dehydrogenase activity
AL504_RS28155	COG1309	transcriptional regulator
AL504_RS28165	COG2197	response regulator
AL504_RS28170	COG2197	response regulator
AL504_RS28175	COG0297	glycogen (starch) synthase activity
AL504_RS28180	COG0110	maltose O-acetyltransferase activity
AL504_RS28185	COG0463	Glycosyl transferase, family 2
AL504_RS28210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS28255	COG0166	Belongs to the GPI family
AL504_RS28260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL504_RS28265	COG1045	serine acetyltransferase
AL504_RS28270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL504_RS28285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_RS28305	COG0598	Magnesium transport protein CorA
AL504_RS28320	COG0601	transmembrane transport
AL504_RS28325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS28330	COG4172	Belongs to the ABC transporter superfamily
AL504_RS28340	COG1846	Transcriptional regulator
AL504_RS28385	COG4964	Belongs to the GSP D family
AL504_RS28440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL504_RS28455	COG3384	dioxygenase
AL504_RS28460	COG0583	DNA-binding transcription factor activity
AL504_RS28470	COG2814	Major facilitator Superfamily
AL504_RS28475	COG1566	PFAM secretion protein HlyD family protein
AL504_RS28495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL504_RS28515	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS28520	COG3321	synthase
AL504_RS28520	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS28520	COG0604	alcohol dehydrogenase
AL504_RS28535	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS28545	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS28550	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS28555	COG3246	L-lysine catabolic process to acetate
AL504_RS28560	COG0371	Dehydrogenase
AL504_RS28565	COG1802	Transcriptional regulator
AL504_RS28570	COG3959	Transketolase, thiamine diphosphate binding domain
AL504_RS28575	COG3958	Transketolase
AL504_RS28580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL504_RS28590	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS28595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS28605	COG0765	amino acid transport
AL504_RS28615	COG2721	sulfolactate sulfo-lyase activity
AL504_RS28625	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS28630	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS28635	COG1414	Transcriptional regulator
AL504_RS28655	COG0596	Alpha beta hydrolase
AL504_RS28675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL504_RS28685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS28690	COG1120	ATPase activity
AL504_RS28705	COG4771	TonB-dependent receptor
AL504_RS28755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS28755	COG0784	Response regulator, receiver
AL504_RS28755	COG2198	Histidine kinase
AL504_RS28755	COG2205	protein histidine kinase activity
AL504_RS28760	COG0477	Major facilitator Superfamily
AL504_RS28770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_RS28780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_RS28800	COG1113	amino acid transport
AL504_RS28815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL504_RS28825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL504_RS28830	COG0366	Alpha amylase catalytic
AL504_RS28835	COG0366	Alpha amylase catalytic
AL504_RS28840	COG0297	glycogen (starch) synthase activity
AL504_RS28845	COG0392	lysyltransferase activity
AL504_RS28850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS28855	COG3568	Endonuclease Exonuclease Phosphatase
AL504_RS28860	COG0387	Pfam Sodium calcium exchanger
AL504_RS28875	COG3685	Protein conserved in bacteria
AL504_RS28885	COG0166	Belongs to the GPI family
AL504_RS28895	COG0668	transmembrane transport
AL504_RS28965	COG1064	alcohol dehydrogenase
AL504_RS28980	COG1850	ribulose-bisphosphate carboxylase activity
AL504_RS28990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS28995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS29000	COG1609	Transcriptional regulator
AL504_RS29010	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS29015	COG0596	Alpha beta hydrolase
AL504_RS29040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL504_RS29055	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29070	COG1396	sequence-specific DNA binding
AL504_RS29175	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AL504_RS29180	COG1116	anion transmembrane transporter activity
AL504_RS29185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS29190	COG1116	anion transmembrane transporter activity
AL504_RS29190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS29195	COG2197	response regulator
AL504_RS29205	COG1131	(ABC) transporter
AL504_RS29210	COG0842	Transport permease protein
AL504_RS29225	COG0183	Belongs to the thiolase family
AL504_RS29250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS29270	COG3321	synthase
AL504_RS29270	COG0604	alcohol dehydrogenase
AL504_RS29285	COG4638	Rieske (2fe-2S)
AL504_RS29315	COG1272	protein, Hemolysin III
AL504_RS29345	COG2169	Transcriptional regulator
AL504_RS29365	COG0583	DNA-binding transcription factor activity
AL504_RS29375	COG4172	Belongs to the ABC transporter superfamily
AL504_RS29380	COG0402	S-adenosylhomocysteine deaminase activity
AL504_RS29385	COG0747	negative chemotaxis
AL504_RS29390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS29400	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29410	COG2814	Major facilitator Superfamily
AL504_RS29415	COG0583	DNA-binding transcription factor activity
AL504_RS29505	COG2267	carboxylic ester hydrolase activity
AL504_RS29510	COG2837	iron assimilation
AL504_RS29545	COG0583	DNA-binding transcription factor activity
AL504_RS29550	COG2814	Major facilitator Superfamily
AL504_RS29555	COG0583	DNA-binding transcription factor activity
AL504_RS29570	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS29585	COG2814	Major facilitator Superfamily
AL504_RS29595	COG1464	Belongs to the NlpA lipoprotein family
AL504_RS29600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL504_RS29605	COG2011	ABC-type metal ion transport system permease component
AL504_RS29640	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29660	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AL504_RS29665	COG0456	acetyltransferase
AL504_RS29665	COG0454	-acetyltransferase
AL504_RS29675	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29680	COG1473	amidohydrolase
AL504_RS29695	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29700	COG2272	Belongs to the type-B carboxylesterase lipase family
AL504_RS29710	COG0583	DNA-binding transcription factor activity
AL504_RS29735	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS29740	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS29750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS29775	COG1522	sequence-specific DNA binding
AL504_RS29790	COG3706	GGDEF domain
AL504_RS29825	COG0625	glutathione transferase activity
AL504_RS29840	COG3530	Putative quorum-sensing-regulated virulence factor
AL504_RS29890	COG0583	DNA-binding transcription factor activity
AL504_RS29910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS29915	COG0477	Major facilitator Superfamily
AL504_RS29925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL504_RS29935	COG0542	response to heat
AL504_RS29960	COG5441	Belongs to the UPF0261 family
AL504_RS29965	COG5564	TIM-barrel signal transduction protein
AL504_RS29980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS29995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL504_RS30005	COG1562	ergosterol biosynthetic process
AL504_RS30015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL504_RS30020	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS30030	COG3971	2-oxopent-4-enoate hydratase activity
AL504_RS30045	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS30050	COG3384	dioxygenase
AL504_RS30080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_RS30090	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS30100	COG2186	Transcriptional regulator
AL504_RS30105	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_RS30110	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS30125	COG0583	DNA-binding transcription factor activity
AL504_RS30130	COG0268	Binds directly to 16S ribosomal RNA
AL504_RS30140	COG0728	peptidoglycan biosynthetic process
AL504_RS30150	COG0563	adenylate kinase activity
AL504_RS30155	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL504_RS30160	COG2835	tetraacyldisaccharide 4'-kinase activity
AL504_RS30170	COG1663	tetraacyldisaccharide 4'-kinase activity
AL504_RS30180	COG0811	peptide transport
AL504_RS30185	COG1570	exodeoxyribonuclease VII activity
AL504_RS30195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL504_RS30205	COG0038	chloride channel
AL504_RS30210	COG0183	Belongs to the thiolase family
AL504_RS30220	COG1278	Cold shock
AL504_RS30225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL504_RS30230	COG2373	Large extracellular alpha-helical protein
AL504_RS30235	COG4953	penicillin-binding protein 1C
AL504_RS30245	COG2995	paraquat-inducible protein a
AL504_RS30250	COG3008	intermembrane lipid transfer
AL504_RS30260	COG0506	proline dehydrogenase activity
AL504_RS30260	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL504_RS30260	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL504_RS30305	COG2271	Major facilitator Superfamily
AL504_RS30325	COG1289	transmembrane transporter activity
AL504_RS30335	COG1566	PFAM secretion protein HlyD family protein
AL504_RS30350	COG0625	glutathione transferase activity
AL504_RS30365	COG1764	response to oxidative stress
AL504_RS30370	COG2423	ornithine cyclodeaminase activity
AL504_RS30380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS30385	COG0765	amino acid transport
AL504_RS30390	COG0765	amino acid transport
AL504_RS30395	COG1126	abc transporter atp-binding protein
AL504_RS30400	COG1902	pentaerythritol trinitrate reductase activity
AL504_RS30450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL504_RS30455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL504_RS30460	COG0196	riboflavin kinase activity
AL504_RS30465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL504_RS30485	COG0210	DNA helicase
AL504_RS30500	COG4771	TonB-dependent receptor
AL504_RS30505	COG4771	TonB-dependent receptor
AL504_RS30510	COG4771	TonB-dependent receptor
AL504_RS30525	COG0488	(ABC) transporter
AL504_RS30530	COG2890	protein-(glutamine-N5) methyltransferase activity
AL504_RS30540	COG2171	N-acyltransferase activity
AL504_RS30710	COG0740	serine-type endopeptidase activity
AL504_RS30875	COG3038	cytochrome b561
AL504_RS30880	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL504_RS30930	COG0583	DNA-binding transcription factor activity
AL504_RS30940	COG0251	oxidation-reduction process
AL504_RS30965	COG1278	Cold shock
AL504_RS30975	COG1278	Cold shock
AL504_RS30985	COG0501	Belongs to the peptidase M48B family
AL504_RS30990	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL504_RS30995	COG0740	serine-type endopeptidase activity
AL504_RS31005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL504_RS31010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL504_RS31020	COG0556	nucleotide-excision repair
AL504_RS31025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL504_RS31035	COG1104	cysteine desulfurase activity
AL504_RS31040	COG0822	iron-sulfur transferase activity
AL504_RS31045	COG0316	Belongs to the HesB IscA family
AL504_RS31050	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL504_RS31055	COG0443	Heat shock 70 kDa protein
AL504_RS31060	COG0633	Ferredoxin
AL504_RS31065	COG2975	iron-sulfur cluster assembly
AL504_RS31070	COG1803	Methylglyoxal synthase
AL504_RS31080	COG1024	Enoyl-CoA hydratase
AL504_RS31110	COG1022	Amp-dependent synthetase and ligase
AL504_RS31120	COG1309	transcriptional regulator
AL504_RS31150	COG3135	benzoate transporter
AL504_RS31165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL504_RS31170	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS31175	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL504_RS31180	COG2271	Major facilitator Superfamily