locus-tag	class	description
AL504_RS00075	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AL504_RS00100	COG1573	uracil-dna glycosylase
AL504_RS00105	COG1573	uracil-dna glycosylase
AL504_RS00160	COG1136	(ABC) transporter
AL504_RS00165	COG0084	hydrolase, TatD family'
AL504_RS00175	COG0745	RESPONSE REGULATOR receiver
AL504_RS00180	COG4771	TonB-dependent receptor
AL504_RS00185	COG4607	ABC-type enterochelin transport system periplasmic component
AL504_RS00190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS00195	COG4605	iron ion homeostasis
AL504_RS00200	COG4604	ABC transporter, ATP-binding protein
AL504_RS00220	COG1595	DNA-templated transcription, initiation
AL504_RS00250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS00260	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS00275	COG3119	arylsulfatase activity
AL504_RS00290	COG2304	oxidoreductase activity
AL504_RS00310	COG0714	Associated with various cellular activities
AL504_RS00315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL504_RS00345	COG3093	addiction module antidote protein HigA
AL504_RS00355	COG2149	membrane
AL504_RS00390	COG3119	arylsulfatase activity
AL504_RS00400	COG0277	FAD linked oxidase domain protein
AL504_RS00415	COG0159	tryptophan synthase activity
AL504_RS00425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_RS00430	COG0477	Major facilitator Superfamily
AL504_RS00435	COG0583	DNA-binding transcription factor activity
AL504_RS00445	COG0583	DNA-binding transcription factor activity
AL504_RS00455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_RS00475	COG0613	PHP domain protein
AL504_RS00510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS00515	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL504_RS00515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS00525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL504_RS00525	COG0047	phosphoribosylformylglycinamidine synthase activity
AL504_RS00550	COG0642	Histidine kinase
AL504_RS00565	COG0583	DNA-binding transcription factor activity
AL504_RS00580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL504_RS00590	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS00600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS00605	COG0583	DNA-binding transcription factor activity
AL504_RS00610	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS00635	COG0745	RESPONSE REGULATOR receiver
AL504_RS00640	COG0784	Response regulator, receiver
AL504_RS00640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS00640	COG2198	Histidine kinase
AL504_RS00640	COG2205	protein histidine kinase activity
AL504_RS00645	COG0583	DNA-binding transcription factor activity
AL504_RS00680	COG1953	Uracil, thiamine, allantoin
AL504_RS00695	COG0477	Major facilitator Superfamily
AL504_RS00735	COG0583	DNA-binding transcription factor activity
AL504_RS00765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS00770	COG3706	GGDEF domain
AL504_RS00780	COG4774	siderophore transport
AL504_RS00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS00825	COG3618	amidohydrolase
AL504_RS00830	COG0583	DNA-binding transcription factor activity
AL504_RS00840	COG1960	acyl-CoA dehydrogenase activity
AL504_RS00850	COG1024	Enoyl-CoA hydratase
AL504_RS00885	COG4773	Receptor
AL504_RS00915	COG4774	siderophore transport
AL504_RS00955	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS00960	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_RS00965	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS00970	COG0583	DNA-binding transcription factor activity
AL504_RS00985	COG0747	negative chemotaxis
AL504_RS00990	COG4608	Belongs to the ABC transporter superfamily
AL504_RS01000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS01005	COG0601	transmembrane transport
AL504_RS01010	COG2072	flavoprotein involved in K transport
AL504_RS01020	COG1058	Belongs to the CinA family
AL504_RS01020	COG1546	Belongs to the CinA family
AL504_RS01055	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS01060	COG3048	D-serine ammonia-lyase activity
AL504_RS01090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_RS01100	COG0583	DNA-binding transcription factor activity
AL504_RS01120	COG3468	outer membrane autotransporter barrel domain protein
AL504_RS01135	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS01135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL504_RS01155	COG4264	IucA IucC family
AL504_RS01170	COG0583	DNA-binding transcription factor activity
AL504_RS01200	COG0640	Transcriptional regulator
AL504_RS01205	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AL504_RS01215	COG0604	alcohol dehydrogenase
AL504_RS01215	COG3321	synthase
AL504_RS01215	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS01230	COG1846	Transcriptional regulator
AL504_RS01250	COG2207	Transcriptional regulator
AL504_RS01255	COG4221	oxidoreductase activity
AL504_RS01270	COG2267	carboxylic ester hydrolase activity
AL504_RS01275	COG0300	oxidoreductase activity
AL504_RS01290	COG0402	S-adenosylhomocysteine deaminase activity
AL504_RS01295	COG2814	Major facilitator Superfamily
AL504_RS01320	COG2207	Transcriptional regulator
AL504_RS01365	COG0583	DNA-binding transcription factor activity
AL504_RS01380	COG0165	Argininosuccinate lyase
AL504_RS01390	COG0456	acetyltransferase
AL504_RS01390	COG1214	PFAM Peptidase M22, glycoprotease
AL504_RS01395	COG0583	DNA-binding transcription factor activity
AL504_RS01410	COG2814	Major facilitator Superfamily
AL504_RS01420	COG0667	Aldo Keto reductase
AL504_RS01425	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL504_RS01430	COG1129	ABC transporter
AL504_RS01440	COG1070	Carbohydrate kinase
AL504_RS01445	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL504_RS01450	COG2188	Transcriptional regulator
AL504_RS01485	COG0456	acetyltransferase
AL504_RS01500	COG1199	ATP-dependent helicase activity
AL504_RS01515	COG0583	DNA-binding transcription factor activity
AL504_RS01530	COG0840	transmembrane signaling receptor activity
AL504_RS01560	COG2203	Gaf domain
AL504_RS01560	COG3706	GGDEF domain
AL504_RS01560	COG4251	negative regulation of phosphorylation
AL504_RS01560	COG5001	Diguanylate cyclase
AL504_RS01565	COG4149	molybdate abc transporter
AL504_RS01570	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_RS01575	COG3842	ATPase activity
AL504_RS01580	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS01585	COG1522	sequence-specific DNA binding
AL504_RS01595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL504_RS01605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL504_RS01605	COG2010	Cytochrome c
AL504_RS01610	COG1335	isochorismatase
AL504_RS01615	COG2309	aminopeptidase activity
AL504_RS01620	COG0596	Alpha beta hydrolase
AL504_RS01630	COG2080	2 iron, 2 sulfur cluster binding
AL504_RS01635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL504_RS01635	COG2010	Cytochrome c
AL504_RS01640	COG0477	Major facilitator Superfamily
AL504_RS01645	COG1846	Transcriptional regulator
AL504_RS01650	COG2814	Major facilitator Superfamily
AL504_RS01655	COG4771	TonB-dependent receptor
AL504_RS01670	COG0583	DNA-binding transcription factor activity
AL504_RS01695	COG0583	DNA-binding transcription factor activity
AL504_RS01700	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL504_RS01710	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS01715	COG1960	acyl-CoA dehydrogenase activity
AL504_RS01720	COG1960	acyl-CoA dehydrogenase activity
AL504_RS01725	COG0183	Belongs to the thiolase family
AL504_RS01730	COG1024	Enoyl-CoA hydratase
AL504_RS01730	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS01735	COG0583	DNA-binding transcription factor activity
AL504_RS01770	COG0148	phosphopyruvate hydratase activity
AL504_RS01780	COG2733	membrane
AL504_RS01790	COG0625	glutathione transferase activity
AL504_RS01800	COG0024	Methionine aminopeptidase
AL504_RS01995	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AL504_RS02005	COG2885	chlorophyll binding
AL504_RS02035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS02055	COG3971	2-oxopent-4-enoate hydratase activity
AL504_RS02060	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS02080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS02085	COG1414	Transcriptional regulator
AL504_RS02095	COG3541	Predicted nucleotidyltransferase
AL504_RS02100	COG1846	Transcriptional regulator
AL504_RS02125	COG0456	acetyltransferase
AL504_RS02135	COG0583	DNA-binding transcription factor activity
AL504_RS02145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL504_RS02155	COG0697	spore germination
AL504_RS02160	COG2207	Transcriptional regulator
AL504_RS02165	COG4941	Belongs to the sigma-70 factor family
AL504_RS02175	COG3795	YCII-related domain
AL504_RS02180	COG3795	YCII-related domain
AL504_RS02220	COG2207	Transcriptional regulator
AL504_RS02235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL504_RS02240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL504_RS02245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL504_RS02250	COG0084	hydrolase, TatD family'
AL504_RS02265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS02270	COG0765	amino acid transport
AL504_RS02275	COG1126	abc transporter atp-binding protein
AL504_RS02280	COG0010	Belongs to the arginase family
AL504_RS02290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL504_RS02300	COG0095	Lipoate-protein ligase
AL504_RS02315	COG0625	glutathione transferase activity
AL504_RS02325	COG1522	sequence-specific DNA binding
AL504_RS02330	COG0386	Belongs to the glutathione peroxidase family
AL504_RS02335	COG2814	Major facilitator Superfamily
AL504_RS02360	COG3395	kinase activity
AL504_RS02365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL504_RS02375	COG0840	transmembrane signaling receptor activity
AL504_RS02385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS02405	COG0513	Belongs to the DEAD box helicase family
AL504_RS02410	COG1414	Transcriptional regulator
AL504_RS02430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS02435	COG3468	outer membrane autotransporter barrel domain protein
AL504_RS02435	COG3210	domain, Protein
AL504_RS02435	COG3468	outer membrane autotransporter barrel domain protein
AL504_RS02435	COG3210	domain, Protein
AL504_RS02455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS02460	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_RS02465	COG4521	taurine ABC transporter
AL504_RS02485	COG1966	Carbon starvation protein
AL504_RS02490	COG2879	small protein
AL504_RS02495	COG0697	spore germination
AL504_RS02500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS02520	COG0783	Belongs to the Dps family
AL504_RS02535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_RS02540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_RS02550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL504_RS02555	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AL504_RS02560	COG0745	RESPONSE REGULATOR receiver
AL504_RS02565	COG5002	protein histidine kinase activity
AL504_RS02570	COG2070	2-Nitropropane dioxygenase
AL504_RS02590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS02630	COG0583	DNA-binding transcription factor activity
AL504_RS02645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS02650	COG0583	DNA-binding transcription factor activity
AL504_RS02675	COG2223	nitrite transmembrane transporter activity
AL504_RS02680	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL504_RS02685	COG1140	nitrate reductase beta subunit
AL504_RS02690	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL504_RS02695	COG2181	nitrate reductase activity
AL504_RS02700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS02705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL504_RS02710	COG0288	reversible hydration of carbon dioxide
AL504_RS02715	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL504_RS02720	COG3850	Histidine kinase
AL504_RS02725	COG2197	response regulator
AL504_RS02730	COG0826	peptidase U32
AL504_RS02735	COG0826	peptidase U32
AL504_RS02740	COG3154	lipid carrier protein
AL504_RS02750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS02755	COG1104	cysteine desulfurase activity
AL504_RS02785	COG1116	anion transmembrane transporter activity
AL504_RS02790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS02795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS02825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL504_RS02840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS02850	COG1802	Transcriptional regulator
AL504_RS02860	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS02885	COG1132	(ABC) transporter
AL504_RS02885	COG2375	cellular response to nickel ion
AL504_RS02895	COG4774	siderophore transport
AL504_RS02900	COG1309	transcriptional regulator
AL504_RS02920	COG0251	oxidation-reduction process
AL504_RS02945	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL504_RS02965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS02970	COG0277	FAD linked oxidase domain protein
AL504_RS02975	COG0436	Aminotransferase
AL504_RS02980	COG0765	amino acid transport
AL504_RS02990	COG1126	abc transporter atp-binding protein
AL504_RS03010	COG0583	DNA-binding transcription factor activity
AL504_RS03045	COG4774	siderophore transport
AL504_RS03075	COG4566	intracellular signal transduction
AL504_RS03080	COG4191	Histidine kinase
AL504_RS03090	COG1846	Transcriptional regulator
AL504_RS03105	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL504_RS03135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL504_RS03145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS03150	COG2070	2-Nitropropane dioxygenase
AL504_RS03155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS03160	COG0765	amino acid transport
AL504_RS03165	COG1126	abc transporter atp-binding protein
AL504_RS03170	COG1595	DNA-templated transcription, initiation
AL504_RS03175	COG3712	iron ion homeostasis
AL504_RS03180	COG4774	siderophore transport
AL504_RS03235	COG0657	acetylesterase activity
AL504_RS03240	COG4774	siderophore transport
AL504_RS03270	COG1120	ATPase activity
AL504_RS03275	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS03280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS03285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL504_RS03325	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AL504_RS03330	COG1136	(ABC) transporter
AL504_RS03335	COG0390	transport system, permease component
AL504_RS03340	COG0586	Pfam SNARE associated Golgi protein
AL504_RS03355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL504_RS03365	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL504_RS03370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS03380	COG0745	RESPONSE REGULATOR receiver
AL504_RS03385	COG0642	Histidine kinase
AL504_RS03395	COG1126	abc transporter atp-binding protein
AL504_RS03400	COG0765	amino acid transport
AL504_RS03405	COG4597	amino acid ABC transporter
AL504_RS03410	COG0436	Aminotransferase
AL504_RS03415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS03420	COG2188	Transcriptional regulator
AL504_RS03440	COG2721	sulfolactate sulfo-lyase activity
AL504_RS03445	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS03475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL504_RS03475	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS03480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS03490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS03495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS03500	COG2358	TRAP transporter, solute receptor (TAXI family
AL504_RS03510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_RS03515	COG4208	sulfate ABC transporter
AL504_RS03530	COG1335	isochorismatase
AL504_RS03535	COG0583	DNA-binding transcription factor activity
AL504_RS03545	COG0747	negative chemotaxis
AL504_RS03550	COG0601	transmembrane transport
AL504_RS03555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS03560	COG0444	Belongs to the ABC transporter superfamily
AL504_RS03575	COG4771	TonB-dependent receptor
AL504_RS03580	COG0583	DNA-binding transcription factor activity
AL504_RS03585	COG0626	cystathionine gamma-synthase activity
AL504_RS03590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS03595	COG4597	amino acid ABC transporter
AL504_RS03600	COG0765	amino acid transport
AL504_RS03605	COG1126	abc transporter atp-binding protein
AL504_RS03625	COG0583	DNA-binding transcription factor activity
AL504_RS03630	COG2957	Belongs to the agmatine deiminase family
AL504_RS03635	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AL504_RS03640	COG0583	DNA-binding transcription factor activity
AL504_RS03660	COG2207	Transcriptional regulator
AL504_RS03675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL504_RS03705	COG0583	DNA-binding transcription factor activity
AL504_RS03730	COG1733	regulation of RNA biosynthetic process
AL504_RS03770	COG0579	oxidoreductase
AL504_RS03795	COG0625	glutathione transferase activity
AL504_RS03820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS03840	COG3971	2-oxopent-4-enoate hydratase activity
AL504_RS03865	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL504_RS03880	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS03900	COG0251	oxidation-reduction process
AL504_RS03910	COG0747	negative chemotaxis
AL504_RS03915	COG0601	transmembrane transport
AL504_RS03925	COG0444	Belongs to the ABC transporter superfamily
AL504_RS03930	COG4608	Belongs to the ABC transporter superfamily
AL504_RS03935	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS03945	COG0531	amino acid
AL504_RS03950	COG2226	methyltransferase
AL504_RS03965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL504_RS03970	COG0626	cystathionine gamma-synthase activity
AL504_RS03975	COG0628	permease
AL504_RS03985	COG0583	DNA-binding transcription factor activity
AL504_RS03990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_RS04015	COG3706	GGDEF domain
AL504_RS04025	COG0789	Transcriptional regulator
AL504_RS04030	COG3706	GGDEF domain
AL504_RS04170	COG0667	Aldo Keto reductase
AL504_RS04175	COG0583	DNA-binding transcription factor activity
AL504_RS04190	COG2205	protein histidine kinase activity
AL504_RS04215	COG1253	flavin adenine dinucleotide binding
AL504_RS04265	COG3300	MHYT domain
AL504_RS04265	COG5001	Diguanylate cyclase
AL504_RS04270	COG1289	transmembrane transporter activity
AL504_RS04280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_RS04295	COG0693	protein deglycase activity
AL504_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS04345	COG2204	response regulator
AL504_RS04350	COG2204	response regulator
AL504_RS04355	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL504_RS04375	COG4771	TonB-dependent receptor
AL504_RS04385	COG2375	cellular response to nickel ion
AL504_RS04385	COG1132	(ABC) transporter
AL504_RS04390	COG1132	(ABC) transporter
AL504_RS04405	COG2814	Major facilitator Superfamily
AL504_RS04425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL504_RS04430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS04455	COG0488	(ABC) transporter
AL504_RS04465	COG0688	phosphatidylethanolamine metabolic process
AL504_RS04495	COG1408	metallophosphoesterase
AL504_RS04505	COG2814	Major facilitator Superfamily
AL504_RS04515	COG1464	Belongs to the NlpA lipoprotein family
AL504_RS04520	COG0010	Belongs to the arginase family
AL504_RS04530	COG2363	Small membrane protein
AL504_RS04535	COG0697	spore germination
AL504_RS04545	COG2133	pyrroloquinoline quinone binding
AL504_RS04550	COG0625	glutathione transferase activity
AL504_RS04555	COG0583	DNA-binding transcription factor activity
AL504_RS04565	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS04570	COG1794	racemase activity, acting on amino acids and derivatives
AL504_RS04590	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS04600	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL504_RS04610	COG1653	transport
AL504_RS04615	COG1175	transmembrane transport
AL504_RS04620	COG0395	ABC-type sugar transport system, permease component
AL504_RS04625	COG3842	ATPase activity
AL504_RS04640	COG2205	protein histidine kinase activity
AL504_RS04645	COG0745	RESPONSE REGULATOR receiver
AL504_RS04660	COG3866	Pectate lyase
AL504_RS04665	COG1560	Kdo2-lipid A biosynthetic process
AL504_RS04665	COG4783	chaperone-mediated protein folding
AL504_RS04690	COG0438	transferase activity, transferring glycosyl groups
AL504_RS04695	COG0457	Tetratricopeptide repeat
AL504_RS04705	COG0783	Belongs to the Dps family
AL504_RS04715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL504_RS04735	COG0583	DNA-binding transcription factor activity
AL504_RS04760	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_RS04765	COG4149	molybdate abc transporter
AL504_RS04770	COG3842	ATPase activity
AL504_RS04775	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS04780	COG1690	Belongs to the RtcB family
AL504_RS04785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL504_RS04790	COG1741	Belongs to the pirin family
AL504_RS04795	COG1741	Belongs to the pirin family
AL504_RS04800	COG0583	DNA-binding transcription factor activity
AL504_RS04805	COG2204	response regulator
AL504_RS04815	COG0174	glutamine synthetase
AL504_RS04820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL504_RS04825	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL504_RS04835	COG0840	transmembrane signaling receptor activity
AL504_RS04840	COG1960	acyl-CoA dehydrogenase activity
AL504_RS04850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL504_RS04855	COG1561	YicC-like family, N-terminal region
AL504_RS04865	COG0833	amino acid
AL504_RS04870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL504_RS04885	COG0791	NLP P60 protein
AL504_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS04895	COG2863	cytochrome
AL504_RS04900	COG3258	Cytochrome c
AL504_RS04905	COG0194	GDP metabolic process
AL504_RS04910	COG1758	RNA polymerase activity
AL504_RS04915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL504_RS04925	COG1335	isochorismatase
AL504_RS04930	COG1126	abc transporter atp-binding protein
AL504_RS04935	COG0765	amino acid transport
AL504_RS04940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS04960	COG2816	NAD+ diphosphatase activity
AL504_RS04980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS05010	COG4336	lyase activity
AL504_RS05015	COG0583	DNA-binding transcription factor activity
AL504_RS05030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS05045	COG0583	DNA-binding transcription factor activity
AL504_RS05055	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL504_RS05060	COG0560	Phosphoserine phosphatase
AL504_RS05065	COG0583	DNA-binding transcription factor activity
AL504_RS05070	COG3842	ATPase activity
AL504_RS05075	COG1178	ABC-type Fe3 transport system permease component
AL504_RS05085	COG4181	ATPase activity
AL504_RS05095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS05105	COG0584	glycerophosphoryl diester phosphodiesterase
AL504_RS05110	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL504_RS05120	COG2986	histidine ammonia-lyase
AL504_RS05130	COG0678	peroxiredoxin activity
AL504_RS05130	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL504_RS05145	COG0789	Transcriptional regulator
AL504_RS05150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL504_RS05175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL504_RS05185	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL504_RS05190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL504_RS05195	COG2252	PERMEase
AL504_RS05205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS05210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS05245	COG0488	(ABC) transporter
AL504_RS05250	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL504_RS05255	COG0590	tRNA wobble adenosine to inosine editing
AL504_RS05270	COG1320	monovalent cation:proton antiporter activity
AL504_RS05275	COG2212	antiporter activity
AL504_RS05280	COG1863	multisubunit Na H antiporter MnhE subunit
AL504_RS05285	COG0651	ATP synthesis coupled electron transport
AL504_RS05290	COG1006	Multisubunit Na H antiporter MnhC subunit
AL504_RS05295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL504_RS05295	COG2111	Na H antiporter
AL504_RS05305	COG4774	siderophore transport
AL504_RS05330	COG0420	3'-5' exonuclease activity
AL504_RS05335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS05370	COG1960	acyl-CoA dehydrogenase activity
AL504_RS05375	COG1959	2 iron, 2 sulfur cluster binding
AL504_RS05380	COG3634	alkyl hydroperoxide reductase activity
AL504_RS05405	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS05410	COG0346	lactoylglutathione lyase activity
AL504_RS05450	COG0395	ABC-type sugar transport system, permease component
AL504_RS05460	COG3842	ATPase activity
AL504_RS05465	COG3842	ATPase activity
AL504_RS05490	COG2130	NADP-dependent
AL504_RS05495	COG1309	transcriptional regulator
AL504_RS05505	COG1131	(ABC) transporter
AL504_RS05510	COG0842	Transport permease protein
AL504_RS05525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL504_RS05555	COG1902	pentaerythritol trinitrate reductase activity
AL504_RS05570	COG0602	queuosine metabolic process
AL504_RS05575	COG0720	synthase
AL504_RS05585	COG1289	transmembrane transporter activity
AL504_RS05595	COG1566	PFAM secretion protein HlyD family protein
AL504_RS05610	COG0028	Belongs to the TPP enzyme family
AL504_RS05620	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS05630	COG0400	carboxylic ester hydrolase activity
AL504_RS05635	COG0833	amino acid
AL504_RS05650	COG0587	DNA-directed DNA polymerase activity
AL504_RS05670	COG0667	Aldo Keto reductase
AL504_RS05705	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS05710	COG0583	DNA-binding transcription factor activity
AL504_RS05730	COG0765	amino acid transport
AL504_RS05735	COG0765	amino acid transport
AL504_RS05740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS05745	COG0436	Aminotransferase
AL504_RS05750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL504_RS05830	COG0840	transmembrane signaling receptor activity
AL504_RS05915	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL504_RS05935	COG4774	siderophore transport
AL504_RS05940	COG2345	Transcriptional regulator
AL504_RS05950	COG1414	Transcriptional regulator
AL504_RS05960	COG0477	Major facilitator Superfamily
AL504_RS05970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS05975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS05985	COG0667	Aldo Keto reductase
AL504_RS05995	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS06000	COG1309	transcriptional regulator
AL504_RS06020	COG1683	Conserved Protein
AL504_RS06040	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS06040	COG1024	Enoyl-CoA hydratase
AL504_RS06055	COG2867	negative regulation of translational initiation
AL504_RS06060	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL504_RS06080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL504_RS06080	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS06085	COG2169	Transcriptional regulator
AL504_RS06085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL504_RS06125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL504_RS06130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL504_RS06145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL504_RS06150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL504_RS06155	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL504_RS06160	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL504_RS06165	COG0750	zinc metalloprotease
AL504_RS06170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL504_RS06180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL504_RS06185	COG0233	cytoplasmic translational termination
AL504_RS06190	COG0528	UMP kinase activity
AL504_RS06195	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL504_RS06200	COG0052	Belongs to the universal ribosomal protein uS2 family
AL504_RS06205	COG0024	Methionine aminopeptidase
AL504_RS06210	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL504_RS06220	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL504_RS06225	COG1451	nucleotide metabolic process
AL504_RS06245	COG0285	dihydrofolate synthase activity
AL504_RS06255	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS06260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS06280	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL504_RS06300	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL504_RS06310	COG1677	Flagellar hook-basal body complex protein FliE
AL504_RS06315	COG1766	The M ring may be actively involved in energy transduction
AL504_RS06320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL504_RS06345	COG1580	Controls the rotational direction of flagella during chemotaxis
AL504_RS06380	COG0840	transmembrane signaling receptor activity
AL504_RS06385	COG0840	transmembrane signaling receptor activity
AL504_RS06395	COG0840	transmembrane signaling receptor activity
AL504_RS06400	COG0840	transmembrane signaling receptor activity
AL504_RS06410	COG1256	bacterial-type flagellum assembly
AL504_RS06435	COG4787	bacterial-type flagellum-dependent cell motility
AL504_RS06450	COG1558	bacterial-type flagellum-dependent cell motility
AL504_RS06455	COG1815	bacterial-type flagellum-dependent cell motility
AL504_RS06465	COG2747	anti-sigma28 factor FlgM
AL504_RS06490	COG0840	transmembrane signaling receptor activity
AL504_RS06495	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL504_RS06500	COG0745	RESPONSE REGULATOR receiver
AL504_RS06505	COG2201	protein-glutamate methylesterase activity
AL504_RS06510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL504_RS06515	COG0840	transmembrane signaling receptor activity
AL504_RS06520	COG0835	chemotaxis
AL504_RS06530	COG0745	RESPONSE REGULATOR receiver
AL504_RS06560	COG4797	methyltransferase
AL504_RS06560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_RS06575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL504_RS06595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL504_RS06605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL504_RS06635	COG0583	DNA-binding transcription factor activity
AL504_RS06645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL504_RS06650	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL504_RS06655	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL504_RS06665	COG4566	intracellular signal transduction
AL504_RS06670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL504_RS06675	COG0339	signal peptide processing
AL504_RS06685	COG1999	signal sequence binding
AL504_RS06710	COG0583	DNA-binding transcription factor activity
AL504_RS06715	COG1187	pseudouridine synthase activity
AL504_RS06720	COG3161	chorismate lyase activity
AL504_RS06725	COG0477	Major facilitator Superfamily
AL504_RS06740	COG2130	NADP-dependent
AL504_RS06745	COG1309	transcriptional regulator
AL504_RS06750	COG4681	YaeQ
AL504_RS06755	COG4172	Belongs to the ABC transporter superfamily
AL504_RS06760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS06765	COG0601	transmembrane transport
AL504_RS06770	COG0747	negative chemotaxis
AL504_RS06780	COG0583	DNA-binding transcription factor activity
AL504_RS06810	COG2165	general secretion pathway protein
AL504_RS06880	COG0668	transmembrane transport
AL504_RS06885	COG0165	Argininosuccinate lyase
AL504_RS06905	COG0022	dehydrogenase e1 component
AL504_RS06915	COG4774	siderophore transport
AL504_RS06940	COG0789	Transcriptional regulator
AL504_RS06960	COG2271	Major facilitator Superfamily
AL504_RS06970	COG0307	riboflavin synthase, alpha
AL504_RS06985	COG1696	Membrane protein involved in D-alanine export
AL504_RS06995	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07030	COG2070	2-Nitropropane dioxygenase
AL504_RS07080	COG0154	amidase activity
AL504_RS07085	COG2814	Major facilitator Superfamily
AL504_RS07095	COG2226	methyltransferase
AL504_RS07105	COG4608	Belongs to the ABC transporter superfamily
AL504_RS07110	COG0444	Belongs to the ABC transporter superfamily
AL504_RS07120	COG0601	transmembrane transport
AL504_RS07125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS07150	COG0747	negative chemotaxis
AL504_RS07165	COG2814	Major facilitator Superfamily
AL504_RS07180	COG0583	DNA-binding transcription factor activity
AL504_RS07195	COG1733	regulation of RNA biosynthetic process
AL504_RS07205	COG0583	DNA-binding transcription factor activity
AL504_RS07210	COG1132	(ABC) transporter
AL504_RS07255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS07265	COG5265	(ABC) transporter
AL504_RS07270	COG1280	lysine exporter protein (LysE YggA)
AL504_RS07310	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS07315	COG2188	Transcriptional regulator
AL504_RS07330	COG0477	Major facilitator Superfamily
AL504_RS07335	COG0235	Class ii aldolase
AL504_RS07365	COG2610	gluconate transmembrane transporter activity
AL504_RS07370	COG0583	DNA-binding transcription factor activity
AL504_RS07375	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07385	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AL504_RS07430	COG1024	Enoyl-CoA hydratase
AL504_RS07435	COG5001	Diguanylate cyclase
AL504_RS07440	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS07445	COG0129	dihydroxy-acid dehydratase activity
AL504_RS07455	COG0583	DNA-binding transcription factor activity
AL504_RS07460	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS07465	COG3246	L-lysine catabolic process to acetate
AL504_RS07480	COG0243	molybdopterin cofactor binding
AL504_RS07485	COG3043	anaerobic respiration
AL504_RS07490	COG3005	denitrification pathway
AL504_RS07495	COG4133	protoheme IX ABC transporter activity
AL504_RS07515	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL504_RS07525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS07555	COG3381	protein complex oligomerization
AL504_RS07570	COG4133	protoheme IX ABC transporter activity
AL504_RS07580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL504_RS07590	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL504_RS07600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS07605	COG3088	subunit of a heme lyase
AL504_RS07625	COG0109	protoheme IX farnesyltransferase activity
AL504_RS07630	COG0583	DNA-binding transcription factor activity
AL504_RS07645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07675	COG2207	Transcriptional regulator
AL504_RS07710	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07725	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AL504_RS07730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL504_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS07745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL504_RS07750	COG0534	Mate efflux family protein
AL504_RS07765	COG0697	spore germination
AL504_RS07770	COG0697	spore germination
AL504_RS07785	COG1280	lysine exporter protein (LysE YggA)
AL504_RS07800	COG1280	lysine exporter protein (LysE YggA)
AL504_RS07805	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL504_RS07810	COG3245	cytochrome
AL504_RS07820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL504_RS07830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL504_RS07855	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS07860	COG1960	acyl-CoA dehydrogenase activity
AL504_RS07875	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_RS07885	COG2814	Major facilitator Superfamily
AL504_RS07900	COG0625	glutathione transferase activity
AL504_RS07910	COG0583	DNA-binding transcription factor activity
AL504_RS07920	COG0583	DNA-binding transcription factor activity
AL504_RS07940	COG0506	proline dehydrogenase activity
AL504_RS07945	COG0697	spore germination
AL504_RS07950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS07955	COG1959	2 iron, 2 sulfur cluster binding
AL504_RS07980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL504_RS07985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL504_RS07995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL504_RS08035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL504_RS08045	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS08050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL504_RS08060	COG1610	YqeY-like protein
AL504_RS08095	COG0457	Tetratricopeptide repeat
AL504_RS08100	COG1649	PFAM Uncharacterised BCR, COG1649
AL504_RS08100	COG0726	polysaccharide deacetylase
AL504_RS08105	COG1215	transferase activity, transferring glycosyl groups
AL504_RS08115	COG2223	nitrite transmembrane transporter activity
AL504_RS08120	COG1917	Cupin 2, conserved barrel domain protein
AL504_RS08120	COG4977	sequence-specific DNA binding
AL504_RS08130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL504_RS08145	COG0656	L-ascorbic acid biosynthetic process
AL504_RS08150	COG5265	(ABC) transporter
AL504_RS08180	COG1116	anion transmembrane transporter activity
AL504_RS08205	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS08210	COG0583	DNA-binding transcription factor activity
AL504_RS08240	COG1522	sequence-specific DNA binding
AL504_RS08265	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS08280	COG0456	acetyltransferase
AL504_RS08285	COG0384	phenazine biosynthesis protein PhzF
AL504_RS08310	COG0494	nUDIX hydrolase
AL504_RS08315	COG2814	Major facilitator Superfamily
AL504_RS08345	COG0072	phenylalanine-tRNA ligase activity
AL504_RS08345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_RS08350	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL504_RS08355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL504_RS08360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL504_RS08370	COG2960	long-chain fatty acid transporting porin activity
AL504_RS08380	COG0347	Belongs to the P(II) protein family
AL504_RS08385	COG0004	ammonium transporteR
AL504_RS08390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL504_RS08395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL504_RS08410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL504_RS08415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL504_RS08425	COG2197	response regulator
AL504_RS08430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL504_RS08435	COG0789	Transcriptional regulator
AL504_RS08465	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS08475	COG0601	transmembrane transport
AL504_RS08480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS08505	COG1609	Transcriptional regulator
AL504_RS08510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL504_RS08515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS08520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS08525	COG0129	dihydroxy-acid dehydratase activity
AL504_RS08530	COG2755	lipolytic protein G-D-S-L family
AL504_RS08530	COG0657	acetylesterase activity
AL504_RS08570	COG0135	phosphoribosylanthranilate isomerase activity
AL504_RS08575	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL504_RS08580	COG0101	tRNA pseudouridine synthase activity
AL504_RS08595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL504_RS08615	COG4783	chaperone-mediated protein folding
AL504_RS08620	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL504_RS08630	COG3706	GGDEF domain
AL504_RS08635	COG5002	protein histidine kinase activity
AL504_RS08645	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL504_RS08655	COG1295	ribonuclease BN
AL504_RS08665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL504_RS08695	COG4964	Belongs to the GSP D family
AL504_RS08890	COG2369	cell adhesion
AL504_RS08900	COG5410	chromosome segregation
AL504_RS09005	COG3723	Recombinational DNA repair protein, rece pathway
AL504_RS09015	COG1475	DNA binding
AL504_RS09035	COG2755	lipolytic protein G-D-S-L family
AL504_RS09035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL504_RS09050	COG0438	transferase activity, transferring glycosyl groups
AL504_RS09075	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL504_RS09080	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL504_RS09085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL504_RS09090	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AL504_RS09095	COG0330	HflC and HflK could
AL504_RS09100	COG0330	HflC and HflK could
AL504_RS09105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL504_RS09110	COG1923	regulation of RNA biosynthetic process
AL504_RS09115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL504_RS09120	COG1160	GTP binding
AL504_RS09125	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL504_RS09130	COG2976	Protein conserved in bacteria
AL504_RS09150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL504_RS09155	COG0105	UTP biosynthetic process
AL504_RS09160	COG0525	valine-tRNA ligase activity
AL504_RS09165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS09170	COG1126	abc transporter atp-binding protein
AL504_RS09175	COG0765	amino acid transport
AL504_RS09180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS09185	COG1396	sequence-specific DNA binding
AL504_RS09190	COG0336	Belongs to the RNA methyltransferase TrmD family
AL504_RS09200	COG0228	four-way junction DNA binding
AL504_RS09210	COG0425	Belongs to the sulfur carrier protein TusA family
AL504_RS09215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL504_RS09230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS09245	COG2076	Multidrug Resistance protein
AL504_RS09250	COG0633	Ferredoxin
AL504_RS09250	COG3217	Mosc domain protein beta barrel domain protein
AL504_RS09255	COG5285	phytanoyl-CoA dioxygenase
AL504_RS09260	COG0662	Cupin 2, conserved barrel domain protein
AL504_RS09285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL504_RS09290	COG2311	Membrane
AL504_RS09295	COG1309	transcriptional regulator
AL504_RS09320	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL504_RS09335	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL504_RS09340	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL504_RS09360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL504_RS09370	COG3391	amine dehydrogenase activity
AL504_RS09400	COG1846	Transcriptional regulator
AL504_RS09410	COG1566	PFAM secretion protein HlyD family protein
AL504_RS09415	COG2814	Major facilitator Superfamily
AL504_RS09425	COG0473	3-isopropylmalate dehydrogenase activity
AL504_RS09430	COG0433	COG0433 Predicted ATPase
AL504_RS09435	COG0217	transcriptional regulatory protein
AL504_RS09440	COG0151	Belongs to the GarS family
AL504_RS09450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL504_RS09455	COG0799	negative regulation of ribosome biogenesis
AL504_RS09460	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL504_RS09470	COG1301	dicarboxylic acid transport
AL504_RS09475	COG4191	Histidine kinase
AL504_RS09480	COG2204	response regulator
AL504_RS09510	COG1530	ribonuclease E activity
AL504_RS09585	COG1196	nuclear chromosome segregation
AL504_RS09775	COG3723	Recombinational DNA repair protein, rece pathway
AL504_RS09845	COG4251	negative regulation of phosphorylation
AL504_RS09845	COG3706	GGDEF domain
AL504_RS09845	COG5001	Diguanylate cyclase
AL504_RS09845	COG2203	Gaf domain
AL504_RS09860	COG0475	glutathione-regulated potassium exporter activity
AL504_RS09860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL504_RS09865	COG1132	(ABC) transporter
AL504_RS09890	COG0726	polysaccharide deacetylase
AL504_RS09905	COG0726	polysaccharide deacetylase
AL504_RS09910	COG0438	transferase activity, transferring glycosyl groups
AL504_RS09925	COG1116	anion transmembrane transporter activity
AL504_RS09930	COG0395	ABC-type sugar transport system, permease component
AL504_RS09935	COG1643	Atp-dependent helicase
AL504_RS09940	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL504_RS09940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL504_RS09945	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL504_RS09955	COG0704	Plays a role in the regulation of phosphate uptake
AL504_RS09965	COG1960	acyl-CoA dehydrogenase activity
AL504_RS09975	COG1322	Protein conserved in bacteria
AL504_RS09995	COG1177	transmembrane transport
AL504_RS10000	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_RS10005	COG3842	ATPase activity
AL504_RS10015	COG3642	lipopolysaccharide core region biosynthetic process
AL504_RS10025	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL504_RS10030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS10040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS10040	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL504_RS10050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL504_RS10055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL504_RS10060	COG0596	Alpha beta hydrolase
AL504_RS10060	COG2945	thiolester hydrolase activity
AL504_RS10080	COG3618	amidohydrolase
AL504_RS10085	COG0583	DNA-binding transcription factor activity
AL504_RS10090	COG5002	protein histidine kinase activity
AL504_RS10100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS10115	COG0137	argininosuccinate synthase activity
AL504_RS10120	COG3158	transport of potassium into the cell
AL504_RS10125	COG0642	Histidine kinase
AL504_RS10155	COG0776	regulation of translation
AL504_RS10160	COG3128	pkhd-type hydroxylase
AL504_RS10170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL504_RS10175	COG0557	exoribonuclease II activity
AL504_RS10205	COG0679	Auxin Efflux Carrier
AL504_RS10210	COG2391	methyltransferase activity
AL504_RS10215	COG0069	glutamate synthase activity
AL504_RS10220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS10230	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AL504_RS10260	COG0653	protein targeting
AL504_RS10290	COG0697	spore germination
AL504_RS10420	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL504_RS10430	COG0628	permease
AL504_RS10460	COG3909	cytochrome
AL504_RS10470	COG0625	glutathione transferase activity
AL504_RS10475	COG0730	response to heat
AL504_RS10480	COG0482	sulfurtransferase activity
AL504_RS10485	COG0583	DNA-binding transcription factor activity
AL504_RS10515	COG0247	lactate metabolic process
AL504_RS10520	COG0277	FAD linked oxidase domain protein
AL504_RS10525	COG0277	FAD linked oxidase domain protein
AL504_RS10530	COG0277	FAD linked oxidase domain protein
AL504_RS10535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL504_RS10540	COG0312	modulator of DNA gyrase
AL504_RS10555	COG0308	aminopeptidase N
AL504_RS10560	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL504_RS10580	COG0436	Aminotransferase
AL504_RS10590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL504_RS10595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL504_RS10615	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS10630	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS10645	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS10675	COG0181	hydroxymethylbilane synthase activity
AL504_RS10680	COG0861	Integral membrane protein TerC family
AL504_RS10685	COG0861	Integral membrane protein TerC family
AL504_RS10690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL504_RS10695	COG0045	succinate-CoA ligase (ADP-forming) activity
AL504_RS10705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL504_RS10720	COG2137	regulation of response to DNA damage stimulus
AL504_RS10725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL504_RS10760	COG0540	Belongs to the ATCase OTCase family
AL504_RS10820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS10855	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL504_RS10865	COG0305	Participates in initiation and elongation during chromosome replication
AL504_RS10875	COG0359	binds to the 23S rRNA
AL504_RS10880	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL504_RS10885	COG2965	DNA replication, synthesis of RNA primer
AL504_RS10890	COG0360	Binds together with S18 to 16S ribosomal RNA
AL504_RS10895	COG3739	integral membrane protein
AL504_RS10900	COG1469	GTP cyclohydrolase I activity
AL504_RS10910	COG0142	geranyltranstransferase activity
AL504_RS10915	COG1722	exodeoxyribonuclease VII activity
AL504_RS10925	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS10945	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_RS10950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL504_RS10960	COG3842	ATPase activity
AL504_RS10965	COG0583	DNA-binding transcription factor activity
AL504_RS10985	COG0501	Belongs to the peptidase M48B family
AL504_RS10990	COG1760	l-serine dehydratase
AL504_RS10995	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL504_RS11000	COG2801	Transposase and inactivated derivatives
AL504_RS11000	COG3415	Transposase
AL504_RS11010	COG0412	Dienelactone hydrolase
AL504_RS11025	COG1611	Belongs to the LOG family
AL504_RS11030	COG1473	amidohydrolase
AL504_RS11035	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS11055	COG1217	gtp-binding protein TYPA
AL504_RS11060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL504_RS11065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL504_RS11070	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL504_RS11075	COG2251	uridine kinase activity
AL504_RS11075	COG0195	Participates in both transcription termination and antitermination
AL504_RS11080	COG0779	Required for maturation of 30S ribosomal subunits
AL504_RS11085	COG1187	pseudouridine synthase activity
AL504_RS11090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL504_RS11100	COG0583	DNA-binding transcription factor activity
AL504_RS11105	COG0523	cobalamin synthesis protein
AL504_RS11110	COG0523	cobalamin synthesis protein
AL504_RS11135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_RS11140	COG0625	glutathione transferase activity
AL504_RS11145	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL504_RS11155	COG2003	Belongs to the UPF0758 family
AL504_RS11160	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL504_RS11165	COG3483	tryptophan 2,3-dioxygenase activity
AL504_RS11180	COG0534	Mate efflux family protein
AL504_RS11190	COG2050	protein possibly involved in aromatic compounds catabolism
AL504_RS11195	COG1024	Enoyl-CoA hydratase
AL504_RS11200	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS11205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL504_RS11210	COG2151	metal-sulfur cluster biosynthetic enzyme
AL504_RS11215	COG3396	Phenylacetate-CoA oxygenase
AL504_RS11220	COG3460	Phenylacetate-CoA oxygenase
AL504_RS11225	COG3396	Phenylacetate-CoA oxygenase
AL504_RS11230	COG3327	negative regulation of DNA-templated transcription, initiation
AL504_RS11235	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL504_RS11240	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL504_RS11245	COG0501	Belongs to the peptidase M48B family
AL504_RS11250	COG1162	GTPase activity
AL504_RS11260	COG0335	large ribosomal subunit rRNA binding
AL504_RS11290	COG0175	sulfate reduction
AL504_RS11300	COG4208	sulfate ABC transporter
AL504_RS11305	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL504_RS11315	COG0450	alkyl hydroperoxide reductase
AL504_RS11320	COG1960	acyl-CoA dehydrogenase activity
AL504_RS11325	COG2985	domain, Protein
AL504_RS11350	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL504_RS11355	COG2951	lytic endotransglycosylase activity
AL504_RS11385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS11390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL504_RS11395	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL504_RS11415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL504_RS11420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL504_RS11430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL504_RS11440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL504_RS11455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL504_RS11490	COG2951	lytic endotransglycosylase activity
AL504_RS11495	COG2833	Protein of unknown function (DUF455)
AL504_RS11510	COG1132	(ABC) transporter
AL504_RS11515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL504_RS11515	COG0189	ligase activity
AL504_RS11520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL504_RS11520	COG0189	ligase activity
AL504_RS11525	COG3237	CsbD-like
AL504_RS11535	COG2823	Periplasmic or secreted lipoprotein
AL504_RS11565	COG2831	hemolysin activation secretion protein
AL504_RS11590	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AL504_RS11595	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS11600	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL504_RS11605	COG1496	oxidoreductase activity
AL504_RS11610	COG0564	pseudouridine synthase activity
AL504_RS11620	COG1199	ATP-dependent helicase activity
AL504_RS11625	COG2183	response to ionizing radiation
AL504_RS11660	COG4774	siderophore transport
AL504_RS11665	COG3712	iron ion homeostasis
AL504_RS11670	COG1595	DNA-templated transcription, initiation
AL504_RS11675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL504_RS11680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL504_RS11685	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL504_RS11690	COG0567	Dehydrogenase, E1 component
AL504_RS11695	COG1522	sequence-specific DNA binding
AL504_RS11700	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL504_RS11715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_RS11720	COG1297	OPT oligopeptide transporter protein
AL504_RS11730	COG0280	phosphate acetyltransferase
AL504_RS11730	COG0281	malic enzyme
AL504_RS11745	COG0372	Belongs to the citrate synthase family
AL504_RS11750	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL504_RS11755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL504_RS11760	COG1053	succinate dehydrogenase
AL504_RS11765	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL504_RS11770	COG2009	succinate dehydrogenase
AL504_RS11775	COG2188	Transcriptional regulator
AL504_RS11780	COG0039	L-malate dehydrogenase activity
AL504_RS11800	COG1981	membrane
AL504_RS11840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL504_RS11850	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL504_RS11865	COG0148	phosphopyruvate hydratase activity
AL504_RS11875	COG0504	CTP synthase activity
AL504_RS11910	COG0747	negative chemotaxis
AL504_RS11915	COG4172	Belongs to the ABC transporter superfamily
AL504_RS11920	COG1446	asparaginase
AL504_RS11930	COG2153	protein acetylation
AL504_RS11955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS11975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL504_RS11980	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL504_RS11985	COG0697	spore germination
AL504_RS11990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL504_RS12000	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AL504_RS12010	COG0791	NLP P60 protein
AL504_RS12020	COG0583	DNA-binding transcription factor activity
AL504_RS12045	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL504_RS12075	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS12085	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL504_RS12095	COG1381	Involved in DNA repair and RecF pathway recombination
AL504_RS12100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL504_RS12105	COG0571	ribonuclease III activity
AL504_RS12110	COG0681	Belongs to the peptidase S26 family
AL504_RS12120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_RS12145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL504_RS12150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL504_RS12160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL504_RS12165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL504_RS12175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL504_RS12185	COG0424	maF-like protein
AL504_RS12195	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL504_RS12200	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL504_RS12205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL504_RS12210	COG0546	phosphoglycolate phosphatase activity
AL504_RS12215	COG0564	pseudouridine synthase activity
AL504_RS12220	COG1530	ribonuclease E activity
AL504_RS12230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL504_RS12235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL504_RS12240	COG0159	tryptophan synthase activity
AL504_RS12250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_RS12260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL504_RS12265	COG3228	Belongs to the MtfA family
AL504_RS12275	COG0251	oxidation-reduction process
AL504_RS12280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL504_RS12300	COG2878	Part of a membrane complex involved in electron transport
AL504_RS12305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL504_RS12340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL504_RS12375	COG1268	BioY protein
AL504_RS12380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AL504_RS12385	COG1122	ATPase activity
AL504_RS12390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_RS12395	COG2917	probably involved in intracellular septation
AL504_RS12405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS12410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL504_RS12420	COG1196	nuclear chromosome segregation
AL504_RS12425	COG0477	Major facilitator Superfamily
AL504_RS12430	COG1573	uracil-dna glycosylase
AL504_RS12435	COG1214	PFAM Peptidase M22, glycoprotease
AL504_RS12450	COG0450	alkyl hydroperoxide reductase
AL504_RS12455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS12465	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL504_RS12470	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL504_RS12475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL504_RS12480	COG0560	Phosphoserine phosphatase
AL504_RS12485	COG3210	domain, Protein
AL504_RS12495	COG4774	siderophore transport
AL504_RS12505	COG1007	ATP synthesis coupled electron transport
AL504_RS12520	COG0713	ATP synthesis coupled electron transport
AL504_RS12530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_RS12535	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL504_RS12540	COG1034	ATP synthesis coupled electron transport
AL504_RS12550	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL504_RS12555	COG0649	NAD binding
AL504_RS12560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_RS12565	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_RS12570	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_RS12575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS12600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_RS12605	COG1597	lipid kinase activity
AL504_RS12625	COG1309	transcriptional regulator
AL504_RS12635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS12655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS12660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS12665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL504_RS12680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS12720	COG0747	negative chemotaxis
AL504_RS12750	COG1522	sequence-specific DNA binding
AL504_RS12755	COG2354	Protein conserved in bacteria
AL504_RS12765	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AL504_RS12770	COG3604	Transcriptional regulator
AL504_RS12785	COG1595	DNA-templated transcription, initiation
AL504_RS12810	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS12815	COG2851	Citrate transporter
AL504_RS12825	COG0642	Histidine kinase
AL504_RS12835	COG4566	intracellular signal transduction
AL504_RS12840	COG4191	Histidine kinase
AL504_RS12870	COG0659	secondary active sulfate transmembrane transporter activity
AL504_RS12880	COG3712	iron ion homeostasis
AL504_RS12885	COG1595	DNA-templated transcription, initiation
AL504_RS12915	COG1116	anion transmembrane transporter activity
AL504_RS12950	COG1910	domain protein
AL504_RS12960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL504_RS13000	COG0840	transmembrane signaling receptor activity
AL504_RS13025	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL504_RS13030	COG0149	triose-phosphate isomerase activity
AL504_RS13035	COG3321	synthase
AL504_RS13035	COG0604	alcohol dehydrogenase
AL504_RS13055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS13065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS13090	COG2819	hydrolase of the alpha beta superfamily
AL504_RS13105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL504_RS13115	COG1185	polyribonucleotide nucleotidyltransferase activity
AL504_RS13120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL504_RS13130	COG1183	phosphatidylcholine synthase activity
AL504_RS13135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL504_RS13140	COG0440	acetolactate synthase activity
AL504_RS13145	COG0028	Belongs to the TPP enzyme family
AL504_RS13150	COG1289	transmembrane transporter activity
AL504_RS13155	COG3022	response to hydroperoxide
AL504_RS13160	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS13180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS13220	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL504_RS13225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL504_RS13230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL504_RS13245	COG0601	transmembrane transport
AL504_RS13265	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL504_RS13265	COG0517	IMP dehydrogenase activity
AL504_RS13270	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS13275	COG0251	oxidation-reduction process
AL504_RS13280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL504_RS13285	COG1674	ftsk spoiiie
AL504_RS13290	COG0492	ferredoxin-NADP+ reductase activity
AL504_RS13295	COG1193	negative regulation of DNA recombination
AL504_RS13305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL504_RS13325	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL504_RS13330	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL504_RS13335	COG2205	protein histidine kinase activity
AL504_RS13340	COG0745	RESPONSE REGULATOR receiver
AL504_RS13355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS13360	COG0840	transmembrane signaling receptor activity
AL504_RS13395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL504_RS13420	COG0612	Peptidase, M16
AL504_RS13430	COG0484	heat shock protein binding
AL504_RS13435	COG0443	Heat shock 70 kDa protein
AL504_RS13445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL504_RS13455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL504_RS13460	COG1420	regulation of RNA biosynthetic process
AL504_RS13470	COG0497	DNA recombination
AL504_RS13475	COG0735	belongs to the Fur family
AL504_RS13480	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL504_RS13490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL504_RS13560	COG0583	DNA-binding transcription factor activity
AL504_RS13570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL504_RS13575	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL504_RS13580	COG0167	dihydroorotate dehydrogenase activity
AL504_RS13595	COG1414	Transcriptional regulator
AL504_RS13600	COG1058	Belongs to the CinA family
AL504_RS13600	COG1546	Belongs to the CinA family
AL504_RS13615	COG0513	Belongs to the DEAD box helicase family
AL504_RS13625	COG4771	TonB-dependent receptor
AL504_RS13630	COG2814	Major facilitator Superfamily
AL504_RS13670	COG4783	chaperone-mediated protein folding
AL504_RS13685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS13690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL504_RS13705	COG0006	proline dipeptidase activity
AL504_RS13715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_RS13740	COG0632	four-way junction helicase activity
AL504_RS13745	COG1090	epimerase
AL504_RS13755	COG2255	four-way junction helicase activity
AL504_RS13760	COG3290	protein histidine kinase activity
AL504_RS13775	COG0514	ATP-dependent DNA helicase (RecQ)
AL504_RS13790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL504_RS13800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS13805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS13810	COG1414	Transcriptional regulator
AL504_RS13820	COG2894	cell division
AL504_RS13825	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL504_RS13840	COG0488	(ABC) transporter
AL504_RS13845	COG2746	aminoglycoside 3-N-acetyltransferase activity
AL504_RS13865	COG4608	Belongs to the ABC transporter superfamily
AL504_RS13870	COG0444	Belongs to the ABC transporter superfamily
AL504_RS13875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS13880	COG0601	transmembrane transport
AL504_RS13885	COG0747	negative chemotaxis
AL504_RS13910	COG4638	Rieske (2fe-2S)
AL504_RS13935	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL504_RS13940	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS13965	COG1216	Glycosyl transferase, family 2
AL504_RS13965	COG0463	Glycosyl transferase, family 2
AL504_RS13985	COG0800	Aldolase
AL504_RS13995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL504_RS14010	COG1595	DNA-templated transcription, initiation
AL504_RS14015	COG3712	iron ion homeostasis
AL504_RS14045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL504_RS14050	COG1538	Outer membrane efflux protein
AL504_RS14055	COG1136	(ABC) transporter
AL504_RS14055	COG0577	efflux transmembrane transporter activity
AL504_RS14060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS14075	COG0259	pyridoxamine-phosphate oxidase activity
AL504_RS14080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS14085	COG0579	oxidoreductase
AL504_RS14095	COG0583	DNA-binding transcription factor activity
AL504_RS14105	COG2175	clavaminate synthase activity
AL504_RS14125	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS14130	COG0583	DNA-binding transcription factor activity
AL504_RS14135	COG1960	acyl-CoA dehydrogenase activity
AL504_RS14140	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS14145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS14150	COG0531	amino acid
AL504_RS14155	COG0405	Gamma-glutamyltransferase
AL504_RS14165	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS14175	COG0114	fumarate hydratase activity
AL504_RS14180	COG0802	atpase or kinase
AL504_RS14185	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL504_RS14195	COG0586	Pfam SNARE associated Golgi protein
AL504_RS14205	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL504_RS14215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL504_RS14230	COG0617	tRNA 3'-terminal CCA addition
AL504_RS14240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL504_RS14245	COG2301	Belongs to the HpcH HpaI aldolase family
AL504_RS14255	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AL504_RS14265	COG1024	Enoyl-CoA hydratase
AL504_RS14275	COG1960	acyl-CoA dehydrogenase activity
AL504_RS14290	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS14300	COG2070	2-Nitropropane dioxygenase
AL504_RS14315	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS14320	COG2030	dehydratase
AL504_RS14325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS14340	COG1024	Enoyl-CoA hydratase
AL504_RS14350	COG0751	glycine-tRNA ligase activity
AL504_RS14355	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL504_RS14360	COG0204	Acyl-transferase
AL504_RS14380	COG0242	peptide deformylase activity
AL504_RS14385	COG1960	acyl-CoA dehydrogenase activity
AL504_RS14390	COG0700	Nucleoside recognition
AL504_RS14395	COG0469	pyruvate kinase activity
AL504_RS14400	COG1929	Belongs to the glycerate kinase type-1 family
AL504_RS14405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL504_RS14410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS14420	COG3178	'Phosphotransferase
AL504_RS14450	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL504_RS14480	COG1595	DNA-templated transcription, initiation
AL504_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS14505	COG2982	Protein involved in outer membrane biogenesis
AL504_RS14510	COG1368	sulfuric ester hydrolase activity
AL504_RS14515	COG2818	Glycosylase
AL504_RS14535	COG0735	belongs to the Fur family
AL504_RS14545	COG0583	DNA-binding transcription factor activity
AL504_RS14550	COG0840	transmembrane signaling receptor activity
AL504_RS14610	COG2011	ABC-type metal ion transport system permease component
AL504_RS14615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL504_RS14620	COG1501	Belongs to the glycosyl hydrolase 31 family
AL504_RS14625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS14625	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL504_RS14630	COG0483	inositol monophosphate 1-phosphatase activity
AL504_RS14635	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS14640	COG1473	amidohydrolase
AL504_RS14645	COG0583	DNA-binding transcription factor activity
AL504_RS14650	COG2855	membrane
AL504_RS14660	COG2239	Acts as a magnesium transporter
AL504_RS14675	COG1522	sequence-specific DNA binding
AL504_RS14680	COG0300	oxidoreductase activity
AL504_RS14690	COG0028	Belongs to the TPP enzyme family
AL504_RS14695	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS14710	COG0653	protein targeting
AL504_RS14715	COG0739	heme binding
AL504_RS14725	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL504_RS14730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL504_RS14740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL504_RS14745	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL504_RS14750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL504_RS14755	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL504_RS14765	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL504_RS14770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL504_RS14775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL504_RS14785	COG3116	cell division
AL504_RS14790	COG0275	rRNA processing
AL504_RS14795	COG2001	Belongs to the MraZ family
AL504_RS14805	COG0488	(ABC) transporter
AL504_RS14810	COG0418	dihydroorotase activity
AL504_RS14815	COG1473	amidohydrolase
AL504_RS14825	COG0583	DNA-binding transcription factor activity
AL504_RS14865	COG1522	sequence-specific DNA binding
AL504_RS14875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_RS14880	COG4654	Cytochrome c, class I
AL504_RS14885	COG0129	dihydroxy-acid dehydratase activity
AL504_RS14930	COG2084	Dehydrogenase
AL504_RS14945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_RS14980	COG0824	Thioesterase
AL504_RS14985	COG0811	peptide transport
AL504_RS14990	COG0848	biopolymer transport protein
AL504_RS15000	COG0823	Involved in the tonB-independent uptake of proteins
AL504_RS15015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS15020	COG1120	ATPase activity
AL504_RS15035	COG1522	sequence-specific DNA binding
AL504_RS15045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL504_RS15060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS15065	COG0697	spore germination
AL504_RS15075	COG1346	cytolysis
AL504_RS15085	COG0583	DNA-binding transcription factor activity
AL504_RS15095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS15115	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS15135	COG0583	DNA-binding transcription factor activity
AL504_RS15150	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL504_RS15155	COG0463	Glycosyl transferase, family 2
AL504_RS15165	COG0786	glutamate:sodium symporter activity
AL504_RS15180	COG1671	Belongs to the UPF0178 family
AL504_RS15195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL504_RS15200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS15210	COG0328	RNA-DNA hybrid ribonuclease activity
AL504_RS15215	COG2226	methyltransferase
AL504_RS15220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL504_RS15225	COG0741	lytic transglycosylase activity
AL504_RS15225	COG1388	LysM domain
AL504_RS15265	COG1366	Belongs to the anti-sigma-factor antagonist family
AL504_RS15270	COG2172	sigma factor antagonist activity
AL504_RS15275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL504_RS15285	COG2770	Histidine kinase
AL504_RS15285	COG2208	phosphoserine phosphatase activity
AL504_RS15315	COG4792	protein secretion
AL504_RS15320	COG4791	protein targeting
AL504_RS15325	COG4794	Type iii secretion
AL504_RS15330	COG4790	Type iii secretion
AL504_RS15335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL504_RS15365	COG4669	(LipO)protein
AL504_RS15440	COG4789	Type iii secretion
AL504_RS15475	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS15485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL504_RS15495	COG1942	4-Oxalocrotonate Tautomerase
AL504_RS15510	COG2719	SpoVR family
AL504_RS15515	COG2718	Belongs to the UPF0229 family
AL504_RS15520	COG2766	serine protein kinase
AL504_RS15535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL504_RS15535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL504_RS15540	COG1335	isochorismatase
AL504_RS15550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL504_RS15555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL504_RS15560	COG1280	lysine exporter protein (LysE YggA)
AL504_RS15570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL504_RS15585	COG0316	Belongs to the HesB IscA family
AL504_RS15595	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL504_RS15600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL504_RS15605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL504_RS15625	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS15640	COG0312	modulator of DNA gyrase
AL504_RS15645	COG3028	Belongs to the UPF0307 family
AL504_RS15660	COG1116	anion transmembrane transporter activity
AL504_RS15665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS15670	COG1335	isochorismatase
AL504_RS15675	COG1042	CoA-binding domain protein
AL504_RS15675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL504_RS15675	COG0045	succinate-CoA ligase (ADP-forming) activity
AL504_RS15680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL504_RS15685	COG2814	Major facilitator Superfamily
AL504_RS15695	COG0583	DNA-binding transcription factor activity
AL504_RS15705	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS15710	COG1522	sequence-specific DNA binding
AL504_RS15740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL504_RS15745	COG1696	Membrane protein involved in D-alanine export
AL504_RS15770	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL504_RS15770	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL504_RS15785	COG2264	protein methyltransferase activity
AL504_RS15790	COG0439	Biotin carboxylase
AL504_RS15795	COG0511	ligase activity, forming carbon-carbon bonds
AL504_RS15800	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL504_RS15805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS15810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL504_RS15815	COG3150	esterase
AL504_RS15820	COG0557	exoribonuclease II activity
AL504_RS15840	COG1175	transmembrane transport
AL504_RS15855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL504_RS15860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL504_RS15870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL504_RS15880	COG1126	abc transporter atp-binding protein
AL504_RS15890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS15895	COG0436	Aminotransferase
AL504_RS15900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL504_RS15925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL504_RS15930	COG1678	Uncharacterized ACR, COG1678
AL504_RS15945	COG0352	thiamine-phosphate diphosphorylase activity
AL504_RS15950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL504_RS15955	COG0741	lytic transglycosylase activity
AL504_RS15965	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS15970	COG1335	isochorismatase
AL504_RS15975	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL504_RS15980	COG4638	Rieske (2fe-2S)
AL504_RS16020	COG1024	Enoyl-CoA hydratase
AL504_RS16025	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS16060	COG0410	ABC transporter
AL504_RS16095	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL504_RS16115	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS16120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS16150	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL504_RS16155	COG0237	dephospho-CoA kinase activity
AL504_RS16175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL504_RS16180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL504_RS16190	COG0477	Major facilitator Superfamily
AL504_RS16225	COG1605	Chorismate mutase
AL504_RS16225	COG0077	Prephenate dehydratase
AL504_RS16235	COG2081	HI0933 family
AL504_RS16240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_RS16265	COG1126	abc transporter atp-binding protein
AL504_RS16270	COG0765	amino acid transport
AL504_RS16275	COG4597	amino acid ABC transporter
AL504_RS16280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS16285	COG2884	Cell division ATP-binding protein ftsE
AL504_RS16290	COG2177	Part of the ABC transporter FtsEX involved in
AL504_RS16315	COG1194	a g-specific adenine glycosylase
AL504_RS16335	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL504_RS16350	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS16365	COG0246	Mannitol dehydrogenase
AL504_RS16370	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS16375	COG1126	abc transporter atp-binding protein
AL504_RS16380	COG0765	amino acid transport
AL504_RS16390	COG1063	alcohol dehydrogenase
AL504_RS16405	COG2186	Transcriptional regulator
AL504_RS16415	COG4771	TonB-dependent receptor
AL504_RS16420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL504_RS16425	COG2022	thiamine diphosphate biosynthetic process
AL504_RS16430	COG0351	phosphomethylpyrimidine kinase
AL504_RS16435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL504_RS16445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL504_RS16455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL504_RS16470	COG2226	methyltransferase
AL504_RS16475	COG0745	RESPONSE REGULATOR receiver
AL504_RS16480	COG5002	protein histidine kinase activity
AL504_RS16500	COG2132	Multicopper oxidase
AL504_RS16515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_RS16530	COG4774	siderophore transport
AL504_RS16555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL504_RS16560	COG1984	allophanate hydrolase subunit 2
AL504_RS16570	COG1802	Transcriptional regulator
AL504_RS16575	COG2860	membrane
AL504_RS16585	COG2223	nitrite transmembrane transporter activity
AL504_RS16590	COG2813	Specifically methylates the guanine in position
AL504_RS16590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_RS16595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_RS16600	COG2188	Transcriptional regulator
AL504_RS16605	COG2721	sulfolactate sulfo-lyase activity
AL504_RS16610	COG2721	sulfolactate sulfo-lyase activity
AL504_RS16615	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS16620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_RS16625	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_RS16655	COG2918	glutathione biosynthetic process
AL504_RS16665	COG2988	succinylglutamate desuccinylase activity
AL504_RS16675	COG0583	DNA-binding transcription factor activity
AL504_RS16685	COG1802	Transcriptional regulator
AL504_RS16700	COG1129	ABC transporter
AL504_RS16720	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS16735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS16760	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS16775	COG1309	transcriptional regulator
AL504_RS16785	COG1024	Enoyl-CoA hydratase
AL504_RS16790	COG1024	Enoyl-CoA hydratase
AL504_RS16795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL504_RS16805	COG0747	negative chemotaxis
AL504_RS16810	COG0583	DNA-binding transcription factor activity
AL504_RS16820	COG2988	succinylglutamate desuccinylase activity
AL504_RS16825	COG4166	transmembrane transport
AL504_RS16830	COG0601	transmembrane transport
AL504_RS16845	COG4608	Belongs to the ABC transporter superfamily
AL504_RS16855	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL504_RS16860	COG2171	N-acyltransferase activity
AL504_RS16870	COG4221	oxidoreductase activity
AL504_RS16875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL504_RS16890	COG0210	DNA helicase
AL504_RS16895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL504_RS16900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL504_RS16910	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL504_RS16920	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL504_RS16925	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL504_RS16930	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL504_RS16945	COG0356	it plays a direct role in the translocation of protons across the membrane
AL504_RS16960	COG1024	Enoyl-CoA hydratase
AL504_RS16975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_RS16990	COG0583	DNA-binding transcription factor activity
AL504_RS16995	COG3473	Maleate cis-trans isomerase
AL504_RS17020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL504_RS17025	COG1131	(ABC) transporter
AL504_RS17035	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS17040	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS17060	COG0583	DNA-binding transcription factor activity
AL504_RS17065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_RS17085	COG0037	tRNA processing
AL504_RS17100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_RS17110	COG2967	ApaG domain
AL504_RS17115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL504_RS17120	COG0546	phosphoglycolate phosphatase activity
AL504_RS17130	COG0512	Glutamine amidotransferase of anthranilate synthase
AL504_RS17135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL504_RS17140	COG0134	indole-3-glycerol-phosphate synthase activity
AL504_RS17145	COG3284	Transcriptional regulator
AL504_RS17150	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS17180	COG0709	Synthesizes selenophosphate from selenide and ATP
AL504_RS17185	COG1305	Transglutaminase-like
AL504_RS17190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS17195	COG1442	glycosyl transferase family 8
AL504_RS17195	COG1216	Glycosyl transferase, family 2
AL504_RS17205	COG3276	selenocysteine insertion sequence binding
AL504_RS17210	COG1921	L-seryl-tRNASec selenium transferase activity
AL504_RS17220	COG2864	formate dehydrogenase
AL504_RS17225	COG0437	4 iron, 4 sulfur cluster binding
AL504_RS17230	COG0243	molybdopterin cofactor binding
AL504_RS17230	COG3383	formate dehydrogenase (NAD+) activity
AL504_RS17235	COG0243	molybdopterin cofactor binding
AL504_RS17235	COG3383	formate dehydrogenase (NAD+) activity
AL504_RS17245	COG1607	acyl-coa hydrolase
AL504_RS17270	COG3064	Membrane
AL504_RS17275	COG3585	molybdate ion transport
AL504_RS17280	COG1116	anion transmembrane transporter activity
AL504_RS17285	COG1464	Belongs to the NlpA lipoprotein family
AL504_RS17290	COG2011	ABC-type metal ion transport system permease component
AL504_RS17305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS17310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS17315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS17320	COG0431	NADPH-dependent FMN reductase
AL504_RS17325	COG1464	Belongs to the NlpA lipoprotein family
AL504_RS17350	COG0747	negative chemotaxis
AL504_RS17360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS17370	COG0589	response to stress
AL504_RS17385	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS17390	COG3069	C4-dicarboxylate transmembrane transporter activity
AL504_RS17400	COG1802	Transcriptional regulator
AL504_RS17460	COG3188	usher protein
AL504_RS17475	COG2814	Major facilitator Superfamily
AL504_RS17480	COG0840	transmembrane signaling receptor activity
AL504_RS17495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL504_RS17500	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL504_RS17510	COG2188	Transcriptional regulator
AL504_RS17525	COG0737	Belongs to the 5'-nucleotidase family
AL504_RS17570	COG0463	Glycosyl transferase, family 2
AL504_RS17575	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL504_RS17585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL504_RS17595	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL504_RS17600	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL504_RS17605	COG5001	Diguanylate cyclase
AL504_RS17610	COG2423	ornithine cyclodeaminase activity
AL504_RS17615	COG0583	DNA-binding transcription factor activity
AL504_RS17620	COG2814	Major facilitator Superfamily
AL504_RS17630	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL504_RS17645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS17650	COG1120	ATPase activity
AL504_RS17655	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS17660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS17665	COG4592	Periplasmic binding protein
AL504_RS17670	COG4774	siderophore transport
AL504_RS17675	COG2207	Transcriptional regulator
AL504_RS17690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS17705	COG1595	DNA-templated transcription, initiation
AL504_RS17750	COG2814	Major facilitator Superfamily
AL504_RS17755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL504_RS17775	COG1999	signal sequence binding
AL504_RS17785	COG1612	heme a metabolic process
AL504_RS17815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL504_RS17835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_RS17860	COG0067	glutamate synthase
AL504_RS17860	COG0069	glutamate synthase activity
AL504_RS17860	COG0070	glutamate synthase
AL504_RS17885	COG1984	allophanate hydrolase subunit 2
AL504_RS17900	COG0511	ligase activity, forming carbon-carbon bonds
AL504_RS17905	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL504_RS17910	COG0583	DNA-binding transcription factor activity
AL504_RS17920	COG0583	DNA-binding transcription factor activity
AL504_RS17925	COG0477	Major facilitator Superfamily
AL504_RS17935	COG2070	2-Nitropropane dioxygenase
AL504_RS17940	COG1127	ABC transporter
AL504_RS17945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL504_RS17950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL504_RS17955	COG2853	Lipoprotein
AL504_RS17965	COG1131	(ABC) transporter
AL504_RS17970	COG0842	Transport permease protein
AL504_RS17980	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL504_RS17985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL504_RS17990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL504_RS17995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL504_RS18000	COG0131	Imidazoleglycerol-phosphate dehydratase
AL504_RS18005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL504_RS18010	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL504_RS18015	COG0107	imidazoleglycerol-phosphate synthase activity
AL504_RS18025	COG0140	phosphoribosyl-ATP diphosphatase activity
AL504_RS18030	COG0537	adenosine 5'-monophosphoramidase activity
AL504_RS18035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL504_RS18040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL504_RS18055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_RS18060	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL504_RS18065	COG1970	mechanosensitive ion channel activity
AL504_RS18070	COG0723	plastoquinol--plastocyanin reductase activity
AL504_RS18075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL504_RS18080	COG2857	Cytochrome c1
AL504_RS18085	COG0625	glutathione transferase activity
AL504_RS18090	COG2969	positive regulation of protein catabolic process
AL504_RS18175	COG5489	Protein of unknown function (DUF736)
AL504_RS18185	COG1396	sequence-specific DNA binding
AL504_RS18215	COG1192	Involved in chromosome partitioning
AL504_RS18230	COG4959	Type IV secretory pathway protease TraF
AL504_RS18255	COG1024	Enoyl-CoA hydratase
AL504_RS18260	COG0183	Belongs to the thiolase family
AL504_RS18265	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS18270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS18290	COG2814	Major facilitator Superfamily
AL504_RS18295	COG1960	acyl-CoA dehydrogenase activity
AL504_RS18300	COG2030	dehydratase
AL504_RS18315	COG0583	DNA-binding transcription factor activity
AL504_RS18335	COG4962	Type ii secretion system protein e
AL504_RS18340	COG3838	Conjugal transfer protein Trbc
AL504_RS18350	COG3451	type IV secretory pathway VirB4
AL504_RS18360	COG3846	protein secretion by the type IV secretion system
AL504_RS18375	COG2948	multi-organism process
AL504_RS18410	COG0583	DNA-binding transcription factor activity
AL504_RS18420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL504_RS18430	COG3708	Transcriptional regulator
AL504_RS18430	COG2207	Transcriptional regulator
AL504_RS18440	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL504_RS18445	COG0747	negative chemotaxis
AL504_RS18450	COG0601	transmembrane transport
AL504_RS18455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS18460	COG4172	Belongs to the ABC transporter superfamily
AL504_RS18465	COG1228	amidohydrolase
AL504_RS18470	COG5339	Protein conserved in bacteria
AL504_RS18475	COG5339	Protein conserved in bacteria
AL504_RS18480	COG0513	Belongs to the DEAD box helicase family
AL504_RS18485	COG1280	lysine exporter protein (LysE YggA)
AL504_RS18490	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL504_RS18505	COG0697	spore germination
AL504_RS18510	COG0583	DNA-binding transcription factor activity
AL504_RS18530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL504_RS18545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS18555	COG1609	Transcriptional regulator
AL504_RS18560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_RS18570	COG1653	transport
AL504_RS18575	COG1175	transmembrane transport
AL504_RS18580	COG0395	ABC-type sugar transport system, permease component
AL504_RS18615	COG0018	arginyl-trna synthetase
AL504_RS18625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL504_RS18650	COG1280	lysine exporter protein (LysE YggA)
AL504_RS18665	COG1742	UPF0060 membrane protein
AL504_RS18680	COG1473	amidohydrolase
AL504_RS18685	COG1960	acyl-CoA dehydrogenase activity
AL504_RS18690	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AL504_RS18695	COG0183	Belongs to the thiolase family
AL504_RS18700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL504_RS18750	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS18765	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS18770	COG1595	DNA-templated transcription, initiation
AL504_RS18790	COG2188	Transcriptional regulator
AL504_RS18800	COG1335	isochorismatase
AL504_RS18830	COG3339	Conserved Protein
AL504_RS18840	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AL504_RS18865	COG4977	sequence-specific DNA binding
AL504_RS18885	COG0210	DNA helicase
AL504_RS18900	COG1595	DNA-templated transcription, initiation
AL504_RS18905	COG3712	iron ion homeostasis
AL504_RS18915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL504_RS18920	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS18935	COG1309	transcriptional regulator
AL504_RS18940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS18945	COG0765	amino acid transport
AL504_RS18950	COG0765	amino acid transport
AL504_RS18970	COG2358	TRAP transporter, solute receptor (TAXI family
AL504_RS18980	COG2922	Belongs to the Smg family
AL504_RS18985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL504_RS19010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS19015	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS19020	COG0028	Belongs to the TPP enzyme family
AL504_RS19025	COG1522	sequence-specific DNA binding
AL504_RS19030	COG3781	membrane
AL504_RS19045	COG2814	Major facilitator Superfamily
AL504_RS19060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_RS19075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL504_RS19085	COG1744	ABC transporter substrate-binding protein PnrA-like
AL504_RS19090	COG3845	ABC transporter
AL504_RS19095	COG4603	Belongs to the binding-protein-dependent transport system permease family
AL504_RS19105	COG0402	S-adenosylhomocysteine deaminase activity
AL504_RS19115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS19120	COG0583	DNA-binding transcription factor activity
AL504_RS19125	COG0251	oxidation-reduction process
AL504_RS19150	COG1177	transmembrane transport
AL504_RS19155	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_RS19160	COG3842	ATPase activity
AL504_RS19170	COG1609	Transcriptional regulator
AL504_RS19225	COG1177	transmembrane transport
AL504_RS19230	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_RS19275	COG1126	abc transporter atp-binding protein
AL504_RS19280	COG0765	amino acid transport
AL504_RS19285	COG0765	amino acid transport
AL504_RS19290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS19295	COG0583	DNA-binding transcription factor activity
AL504_RS19305	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL504_RS19315	COG1741	Belongs to the pirin family
AL504_RS19330	COG0583	DNA-binding transcription factor activity
AL504_RS19340	COG0592	DNA-directed DNA polymerase activity
AL504_RS19345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL504_RS19350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL504_RS19355	COG0594	ribonuclease P activity
AL504_RS19360	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL504_RS19370	COG0753	catalase activity
AL504_RS19375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL504_RS19385	COG3712	iron ion homeostasis
AL504_RS19395	COG2175	clavaminate synthase activity
AL504_RS19400	COG1473	amidohydrolase
AL504_RS19405	COG4608	Belongs to the ABC transporter superfamily
AL504_RS19410	COG0444	Belongs to the ABC transporter superfamily
AL504_RS19415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS19420	COG0601	transmembrane transport
AL504_RS19430	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL504_RS19440	COG0038	chloride channel
AL504_RS19450	COG2205	protein histidine kinase activity
AL504_RS19470	COG0436	Aminotransferase
AL504_RS19475	COG3180	Ammonia monooxygenase
AL504_RS19480	COG1278	Cold shock
AL504_RS19485	COG0445	tRNA wobble uridine modification
AL504_RS19490	COG0357	Ribosomal RNA small subunit methyltransferase G
AL504_RS19495	COG1192	Involved in chromosome partitioning
AL504_RS19505	COG1475	DNA binding
AL504_RS19510	COG0252	asparaginase activity
AL504_RS19515	COG0583	DNA-binding transcription factor activity
AL504_RS19540	COG1349	DNA-binding transcription factor activity
AL504_RS19550	COG3842	ATPase activity
AL504_RS19555	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_RS19595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL504_RS19605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL504_RS19615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL504_RS19620	COG0081	regulation of translation
AL504_RS19625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL504_RS19630	COG0222	ribosome binding
AL504_RS19635	COG0085	RNA polymerase activity
AL504_RS19640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL504_RS19655	COG5002	protein histidine kinase activity
AL504_RS19670	COG0745	RESPONSE REGULATOR receiver
AL504_RS19675	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL504_RS19680	COG0049	tRNA binding
AL504_RS19685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL504_RS19690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL504_RS19695	COG0051	transcription antitermination factor activity, RNA binding
AL504_RS19700	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL504_RS19710	COG0089	rRNA binding
AL504_RS19715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL504_RS19720	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL504_RS19725	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL504_RS19730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL504_RS19735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL504_RS19740	COG0255	Belongs to the universal ribosomal protein uL29 family
AL504_RS19745	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL504_RS19760	COG3307	-O-antigen
AL504_RS19770	COG1215	transferase activity, transferring glycosyl groups
AL504_RS19785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL504_RS19825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL504_RS19845	COG0455	bacterial-type flagellum organization
AL504_RS19850	COG1215	transferase activity, transferring glycosyl groups
AL504_RS19855	COG1215	transferase activity, transferring glycosyl groups
AL504_RS19860	COG1215	transferase activity, transferring glycosyl groups
AL504_RS19865	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AL504_RS19870	COG0457	Tetratricopeptide repeat
AL504_RS19930	COG2207	Transcriptional regulator
AL504_RS19950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL504_RS19955	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL504_RS19960	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL504_RS19965	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL504_RS19970	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL504_RS19975	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL504_RS19980	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL504_RS19985	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL504_RS19990	COG1841	ribosomal large subunit assembly
AL504_RS19995	COG0200	Binds to the 23S rRNA
AL504_RS20000	COG0201	protein transport
AL504_RS20005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL504_RS20010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL504_RS20015	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL504_RS20020	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL504_RS20025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL504_RS20030	COG0202	RNA polymerase activity
AL504_RS20035	COG0203	ribosomal protein L17
AL504_RS20045	COG1324	tolerance protein
AL504_RS20050	COG4232	protein-disulfide reductase activity
AL504_RS20065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL504_RS20075	COG1333	cytochrome c biogenesis protein
AL504_RS20080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL504_RS20095	COG1965	Belongs to the frataxin family
AL504_RS20105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL504_RS20110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL504_RS20115	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL504_RS20120	COG0625	glutathione transferase activity
AL504_RS20130	COG2814	Major facilitator Superfamily
AL504_RS20140	COG2226	methyltransferase
AL504_RS20175	COG2186	Transcriptional regulator
AL504_RS20200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS20205	COG1956	GAF domain-containing protein
AL504_RS20210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS20225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL504_RS20250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL504_RS20255	COG3568	Endonuclease Exonuclease Phosphatase
AL504_RS20260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS20270	COG2814	Major facilitator Superfamily
AL504_RS20300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL504_RS20335	COG1134	teichoic acid transport
AL504_RS20345	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS20350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL504_RS20360	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL504_RS20370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL504_RS20380	COG2089	acid synthase
AL504_RS20385	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL504_RS20390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL504_RS20395	COG1088	dTDP-glucose 4,6-dehydratase activity
AL504_RS20420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL504_RS20425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL504_RS20445	COG0673	inositol 2-dehydrogenase activity
AL504_RS20450	COG0859	PFAM glycosyl transferase family 9
AL504_RS20460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AL504_RS20470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL504_RS20495	COG1686	Belongs to the peptidase S11 family
AL504_RS20505	COG2921	Belongs to the UPF0250 family
AL504_RS20510	COG0321	lipoyl(octanoyl) transferase activity
AL504_RS20525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL504_RS20530	COG2096	Adenosyltransferase
AL504_RS20540	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL504_RS20545	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL504_RS20555	COG0523	cobalamin synthesis protein
AL504_RS20560	COG0735	belongs to the Fur family
AL504_RS20575	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL504_RS20585	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL504_RS20590	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL504_RS20600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL504_RS20605	COG1560	Kdo2-lipid A biosynthetic process
AL504_RS20615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL504_RS20620	COG0154	amidase activity
AL504_RS20625	COG0477	Major facilitator Superfamily
AL504_RS20635	COG0583	DNA-binding transcription factor activity
AL504_RS20640	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS20650	COG0066	3-isopropylmalate dehydratase activity
AL504_RS20665	COG0438	transferase activity, transferring glycosyl groups
AL504_RS20670	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL504_RS20675	COG1950	PFAM Membrane protein of
AL504_RS20700	COG1305	Transglutaminase-like
AL504_RS20710	COG2308	Evidence 4 Homologs of previously reported genes of
AL504_RS20715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL504_RS20735	COG0513	Belongs to the DEAD box helicase family
AL504_RS20740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL504_RS20750	COG3210	domain, Protein
AL504_RS20750	COG3210	domain, Protein
AL504_RS20765	COG0351	phosphomethylpyrimidine kinase
AL504_RS20765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL504_RS20765	COG0352	thiamine-phosphate diphosphorylase activity
AL504_RS20780	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS20800	COG3189	MarR family transcriptional regulator
AL504_RS20830	COG0640	Transcriptional regulator
AL504_RS20890	COG1846	Transcriptional regulator
AL504_RS20895	COG1764	response to oxidative stress
AL504_RS20925	COG0583	DNA-binding transcription factor activity
AL504_RS20940	COG0583	DNA-binding transcription factor activity
AL504_RS20950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL504_RS20955	COG0708	Exodeoxyribonuclease III
AL504_RS20960	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL504_RS20975	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL504_RS20980	COG0154	amidase activity
AL504_RS20985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL504_RS20990	COG1077	Cell shape determining protein MreB Mrl
AL504_RS20995	COG1792	Involved in formation and maintenance of cell shape
AL504_RS21005	COG0768	penicillin binding
AL504_RS21010	COG0772	Belongs to the SEDS family
AL504_RS21020	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_RS21025	COG0471	metal ion transport
AL504_RS21030	COG1309	transcriptional regulator
AL504_RS21040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL504_RS21050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_RS21060	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL504_RS21065	COG0792	nuclease activity
AL504_RS21075	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL504_RS21085	COG1660	Displays ATPase and GTPase activities
AL504_RS21100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS21105	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AL504_RS21115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL504_RS21120	COG1137	ATPase activity
AL504_RS21145	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL504_RS21160	COG1294	oxidase, subunit
AL504_RS21170	COG4988	ABC transporter
AL504_RS21175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL504_RS21180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL504_RS21195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS21200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL504_RS21205	COG1238	metal cluster binding
AL504_RS21220	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS21225	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL504_RS21230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS21235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS21250	COG0758	DNA mediated transformation
AL504_RS21255	COG0242	peptide deformylase activity
AL504_RS21260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL504_RS21270	COG0546	phosphoglycolate phosphatase activity
AL504_RS21290	COG1733	regulation of RNA biosynthetic process
AL504_RS21300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL504_RS21305	COG1280	lysine exporter protein (LysE YggA)
AL504_RS21310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL504_RS21310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL504_RS21320	COG5000	phosphorelay sensor kinase activity
AL504_RS21325	COG2204	response regulator
AL504_RS21330	COG0569	domain protein
AL504_RS21335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL504_RS21340	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AL504_RS21345	COG2226	methyltransferase
AL504_RS21360	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS21365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL504_RS21370	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL504_RS21375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL504_RS21380	COG1054	Belongs to the UPF0176 family
AL504_RS21385	COG0588	phosphoglycerate mutase activity
AL504_RS21390	COG4942	peptidase
AL504_RS21395	COG0793	Belongs to the peptidase S41A family
AL504_RS21400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL504_RS21405	COG3300	MHYT domain
AL504_RS21405	COG5001	Diguanylate cyclase
AL504_RS21410	COG2186	Transcriptional regulator
AL504_RS21425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_RS21425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_RS21440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL504_RS21445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL504_RS21450	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL504_RS21455	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL504_RS21460	COG0142	geranyltranstransferase activity
AL504_RS21485	COG2986	histidine ammonia-lyase
AL504_RS21550	COG0235	Class ii aldolase
AL504_RS21555	COG3622	Belongs to the hyi family
AL504_RS21560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS21565	COG2084	Dehydrogenase
AL504_RS21570	COG3395	kinase activity
AL504_RS21575	COG2186	Transcriptional regulator
AL504_RS21600	COG3622	Belongs to the hyi family
AL504_RS21620	COG1522	sequence-specific DNA binding
AL504_RS21625	COG1280	lysine exporter protein (LysE YggA)
AL504_RS21640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL504_RS21645	COG2890	protein-(glutamine-N5) methyltransferase activity
AL504_RS21650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL504_RS21665	COG1464	Belongs to the NlpA lipoprotein family
AL504_RS21685	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS21715	COG0477	Major facilitator Superfamily
AL504_RS21720	COG0583	DNA-binding transcription factor activity
AL504_RS21730	COG0583	DNA-binding transcription factor activity
AL504_RS21745	COG0625	glutathione transferase activity
AL504_RS21750	COG1053	succinate dehydrogenase
AL504_RS21760	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS21780	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS21790	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS21795	COG1802	Transcriptional regulator
AL504_RS21800	COG0288	reversible hydration of carbon dioxide
AL504_RS21820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_RS21830	COG4829	muconolactone delta-isomerase
AL504_RS21835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_RS21845	COG1414	Transcriptional regulator
AL504_RS21850	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS21855	COG2031	fatty acid transporter
AL504_RS21860	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS21865	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL504_RS21870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL504_RS21890	COG0583	DNA-binding transcription factor activity
AL504_RS21895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS21910	COG0129	dihydroxy-acid dehydratase activity
AL504_RS21915	COG0583	DNA-binding transcription factor activity
AL504_RS21920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL504_RS21925	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL504_RS21935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL504_RS21940	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS21945	COG0410	ABC transporter
AL504_RS21970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL504_RS21980	COG2186	Transcriptional regulator
AL504_RS21990	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AL504_RS22015	COG0583	DNA-binding transcription factor activity
AL504_RS22020	COG0628	permease
AL504_RS22030	COG0477	Major facilitator Superfamily
AL504_RS22050	COG1695	Transcriptional regulator
AL504_RS22060	COG0583	DNA-binding transcription factor activity
AL504_RS22195	COG0583	DNA-binding transcription factor activity
AL504_RS22200	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS22210	COG3246	L-lysine catabolic process to acetate
AL504_RS22215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL504_RS22220	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL504_RS22240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_RS22250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS22265	COG3657	addiction module killer protein
AL504_RS22280	COG2233	PERMEase
AL504_RS22290	COG0326	Molecular chaperone. Has ATPase activity
AL504_RS22295	COG1396	sequence-specific DNA binding
AL504_RS22300	COG3550	peptidyl-serine autophosphorylation
AL504_RS22305	COG2814	Major facilitator Superfamily
AL504_RS22310	COG4774	siderophore transport
AL504_RS22325	COG1131	(ABC) transporter
AL504_RS22330	COG2271	Major facilitator Superfamily
AL504_RS22335	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS22340	COG0800	Aldolase
AL504_RS22350	COG1414	Transcriptional regulator
AL504_RS22370	COG3550	peptidyl-serine autophosphorylation
AL504_RS22400	COG0583	DNA-binding transcription factor activity
AL504_RS22405	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS22425	COG0625	glutathione transferase activity
AL504_RS22440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL504_RS22445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL504_RS22450	COG1652	LysM domain
AL504_RS22470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL504_RS22475	COG0583	DNA-binding transcription factor activity
AL504_RS22480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS22485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS22515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL504_RS22535	COG3246	L-lysine catabolic process to acetate
AL504_RS22540	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS22550	COG0477	Major facilitator Superfamily
AL504_RS22580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_RS22595	COG2205	protein histidine kinase activity
AL504_RS22615	COG0165	Argininosuccinate lyase
AL504_RS22625	COG2828	Protein conserved in bacteria
AL504_RS22640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL504_RS22650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL504_RS22690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL504_RS22705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL504_RS22715	COG1234	tRNA 3'-trailer cleavage
AL504_RS22725	COG0625	glutathione transferase activity
AL504_RS22735	COG3258	Cytochrome c
AL504_RS22770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS22780	COG1294	oxidase, subunit
AL504_RS22785	COG1271	oxidase subunit
AL504_RS22790	COG1942	4-Oxalocrotonate Tautomerase
AL504_RS22795	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS22805	COG0697	spore germination
AL504_RS22810	COG0583	DNA-binding transcription factor activity
AL504_RS22815	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS22825	COG0842	Transport permease protein
AL504_RS22830	COG0842	Transport permease protein
AL504_RS22830	COG1129	ABC transporter
AL504_RS22835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS22845	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL504_RS22855	COG4774	siderophore transport
AL504_RS22865	COG1595	DNA-templated transcription, initiation
AL504_RS22870	COG2200	EAL domain
AL504_RS22895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL504_RS22900	COG0745	RESPONSE REGULATOR receiver
AL504_RS22910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL504_RS22910	COG2755	lipolytic protein G-D-S-L family
AL504_RS22925	COG1054	Belongs to the UPF0176 family
AL504_RS22930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_RS22930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_RS22940	COG0489	protein tyrosine kinase activity
AL504_RS22955	COG0717	Belongs to the dCTP deaminase family
AL504_RS22965	COG3706	GGDEF domain
AL504_RS22985	COG2081	HI0933 family
AL504_RS23000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL504_RS23005	COG0509	glycine decarboxylation via glycine cleavage system
AL504_RS23010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL504_RS23010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL504_RS23025	COG0154	amidase activity
AL504_RS23030	COG4172	Belongs to the ABC transporter superfamily
AL504_RS23035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS23040	COG0601	transmembrane transport
AL504_RS23045	COG0747	negative chemotaxis
AL504_RS23060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL504_RS23065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS23090	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AL504_RS23095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL504_RS23100	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL504_RS23115	COG0438	transferase activity, transferring glycosyl groups
AL504_RS23125	COG0438	transferase activity, transferring glycosyl groups
AL504_RS23130	COG0438	transferase activity, transferring glycosyl groups
AL504_RS23135	COG0438	transferase activity, transferring glycosyl groups
AL504_RS23140	COG0405	Gamma-glutamyltransferase
AL504_RS23145	COG0166	Belongs to the GPI family
AL504_RS23160	COG0277	FAD linked oxidase domain protein
AL504_RS23165	COG0745	RESPONSE REGULATOR receiver
AL504_RS23170	COG2205	protein histidine kinase activity
AL504_RS23180	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL504_RS23180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS23190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS23200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS23205	COG2186	Transcriptional regulator
AL504_RS23210	COG1368	sulfuric ester hydrolase activity
AL504_RS23215	COG0204	Acyl-transferase
AL504_RS23250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL504_RS23265	COG0840	transmembrane signaling receptor activity
AL504_RS23270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL504_RS23290	COG0193	aminoacyl-tRNA hydrolase activity
AL504_RS23300	COG0012	GTP binding
AL504_RS23310	COG4804	nuclease activity
AL504_RS23320	COG0488	(ABC) transporter
AL504_RS23335	COG2814	Major facilitator Superfamily
AL504_RS23350	COG3135	benzoate transporter
AL504_RS23355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL504_RS23360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL504_RS23365	COG0742	ribosomal rna small subunit methyltransferase
AL504_RS23390	COG3639	organic phosphonate transmembrane transporter activity
AL504_RS23395	COG3639	organic phosphonate transmembrane transporter activity
AL504_RS23400	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL504_RS23425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL504_RS23430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL504_RS23445	COG1546	Belongs to the CinA family
AL504_RS23445	COG1058	Belongs to the CinA family
AL504_RS23450	COG0284	orotidine-5'-phosphate decarboxylase activity
AL504_RS23455	COG1252	NADH dehydrogenase
AL504_RS23460	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL504_RS23465	COG0246	Mannitol dehydrogenase
AL504_RS23475	COG1137	ATPase activity
AL504_RS23500	COG1917	Cupin 2, conserved barrel domain protein
AL504_RS23520	COG4774	siderophore transport
AL504_RS23535	COG1846	Transcriptional regulator
AL504_RS23545	COG0459	protein refolding
AL504_RS23550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL504_RS23575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS23600	COG0372	Belongs to the citrate synthase family
AL504_RS23615	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS23620	COG2207	Transcriptional regulator
AL504_RS23630	COG0583	DNA-binding transcription factor activity
AL504_RS23645	COG0243	molybdopterin cofactor binding
AL504_RS23650	COG0038	chloride channel
AL504_RS23655	COG4191	Histidine kinase
AL504_RS23680	COG2200	EAL domain
AL504_RS23685	COG0300	oxidoreductase activity
AL504_RS23700	COG1132	(ABC) transporter
AL504_RS23700	COG2375	cellular response to nickel ion
AL504_RS23705	COG1132	(ABC) transporter
AL504_RS23710	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS23715	COG4605	iron ion homeostasis
AL504_RS23720	COG4604	ABC transporter, ATP-binding protein
AL504_RS23725	COG4607	ABC-type enterochelin transport system periplasmic component
AL504_RS23730	COG4774	siderophore transport
AL504_RS23755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_RS23780	COG0657	acetylesterase activity
AL504_RS23800	COG0384	phenazine biosynthesis protein PhzF
AL504_RS23825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL504_RS23835	COG0745	RESPONSE REGULATOR receiver
AL504_RS23865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS23880	COG0277	FAD linked oxidase domain protein
AL504_RS23895	COG0793	Belongs to the peptidase S41A family
AL504_RS23910	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS23915	COG2267	carboxylic ester hydrolase activity
AL504_RS23925	COG0583	DNA-binding transcription factor activity
AL504_RS23940	COG0154	amidase activity
AL504_RS23955	COG1595	DNA-templated transcription, initiation
AL504_RS23970	COG4772	TonB-dependent receptor
AL504_RS23975	COG3712	iron ion homeostasis
AL504_RS23980	COG1595	DNA-templated transcription, initiation
AL504_RS24000	COG0583	DNA-binding transcription factor activity
AL504_RS24005	COG0583	DNA-binding transcription factor activity
AL504_RS24020	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS24030	COG0697	spore germination
AL504_RS24035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS24045	COG1960	acyl-CoA dehydrogenase activity
AL504_RS24050	COG0583	DNA-binding transcription factor activity
AL504_RS24055	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS24060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS24080	COG2814	Major facilitator Superfamily
AL504_RS24115	COG0431	NADPH-dependent FMN reductase
AL504_RS24120	COG0798	PFAM Bile acid sodium symporter
AL504_RS24155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS24210	COG4172	Belongs to the ABC transporter superfamily
AL504_RS24215	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL504_RS24215	COG1793	dna ligase
AL504_RS24220	COG1793	dna ligase
AL504_RS24225	COG1201	RNA secondary structure unwinding
AL504_RS24235	COG1132	(ABC) transporter
AL504_RS24250	COG4771	TonB-dependent receptor
AL504_RS24290	COG3712	iron ion homeostasis
AL504_RS24300	COG0028	Belongs to the TPP enzyme family
AL504_RS24355	COG0583	DNA-binding transcription factor activity
AL504_RS24360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_RS24370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL504_RS24385	COG0596	Alpha beta hydrolase
AL504_RS24395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS24420	COG0740	serine-type endopeptidase activity
AL504_RS24430	COG0640	Transcriptional regulator
AL504_RS24435	COG2203	Gaf domain
AL504_RS24435	COG2199	diguanylate cyclase activity
AL504_RS24440	COG0840	transmembrane signaling receptor activity
AL504_RS24465	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS24470	COG0583	DNA-binding transcription factor activity
AL504_RS24475	COG0456	acetyltransferase
AL504_RS24485	COG0023	Translation Initiation Factor
AL504_RS24490	COG0583	DNA-binding transcription factor activity
AL504_RS24495	COG0656	L-ascorbic acid biosynthetic process
AL504_RS24505	COG0667	Aldo Keto reductase
AL504_RS24515	COG0243	molybdopterin cofactor binding
AL504_RS24520	COG2146	nitrite reductase [NAD(P)H] activity
AL504_RS24520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL504_RS24525	COG2146	nitrite reductase [NAD(P)H] activity
AL504_RS24525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL504_RS24530	COG3707	response regulator
AL504_RS24555	COG2197	response regulator
AL504_RS24580	COG0625	glutathione transferase activity
AL504_RS24595	COG2814	Major facilitator Superfamily
AL504_RS24605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS24610	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS24620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL504_RS24625	COG1845	cytochrome c oxidase, subunit III
AL504_RS24630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL504_RS24635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL504_RS24640	COG0477	Major facilitator Superfamily
AL504_RS24650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS24655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_RS24695	COG0583	DNA-binding transcription factor activity
AL504_RS24710	COG4106	trans-aconitate 2-methyltransferase activity
AL504_RS24715	COG2207	Transcriptional regulator
AL504_RS24720	COG2807	transmembrane transport
AL504_RS24745	COG0330	HflC and HflK could
AL504_RS24750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL504_RS24765	COG3712	iron ion homeostasis
AL504_RS24775	COG4221	oxidoreductase activity
AL504_RS24790	COG3712	iron ion homeostasis
AL504_RS24800	COG1595	DNA-templated transcription, initiation
AL504_RS24805	COG3712	iron ion homeostasis
AL504_RS24820	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL504_RS24835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL504_RS24840	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS24845	COG1285	pathogenesis
AL504_RS24850	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL504_RS24865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL504_RS24890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS24895	COG1396	sequence-specific DNA binding
AL504_RS24915	COG0583	DNA-binding transcription factor activity
AL504_RS24950	COG0697	spore germination
AL504_RS24955	COG2207	Transcriptional regulator
AL504_RS24955	COG1917	Cupin 2, conserved barrel domain protein
AL504_RS24965	COG0281	malic enzyme
AL504_RS24965	COG0280	phosphate acetyltransferase
AL504_RS24985	COG4772	TonB-dependent receptor
AL504_RS25000	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL504_RS25005	COG1845	cytochrome c oxidase, subunit III
AL504_RS25010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL504_RS25020	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AL504_RS25040	COG1999	signal sequence binding
AL504_RS25060	COG4942	peptidase
AL504_RS25060	COG1388	LysM domain
AL504_RS25065	COG1126	abc transporter atp-binding protein
AL504_RS25070	COG0765	amino acid transport
AL504_RS25075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS25080	COG3191	aminopeptidase activity
AL504_RS25085	COG1272	protein, Hemolysin III
AL504_RS25090	COG1522	sequence-specific DNA binding
AL504_RS25100	COG1113	amino acid transport
AL504_RS25105	COG0583	DNA-binding transcription factor activity
AL504_RS25130	COG2378	regulation of single-species biofilm formation
AL504_RS25160	COG1595	DNA-templated transcription, initiation
AL504_RS25165	COG3712	iron ion homeostasis
AL504_RS25175	COG3720	iron ion transport
AL504_RS25180	COG4558	Periplasmic binding protein
AL504_RS25185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS25190	COG1120	ATPase activity
AL504_RS25195	COG1666	GTP binding
AL504_RS25210	COG0671	phosphoesterase, PA-phosphatase related
AL504_RS25220	COG4585	Histidine kinase
AL504_RS25240	COG4774	siderophore transport
AL504_RS25265	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS25305	COG0456	acetyltransferase
AL504_RS25310	COG0583	DNA-binding transcription factor activity
AL504_RS25315	COG2828	Protein conserved in bacteria
AL504_RS25335	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS25350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL504_RS25385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL504_RS25390	COG0583	DNA-binding transcription factor activity
AL504_RS25415	COG2223	nitrite transmembrane transporter activity
AL504_RS25425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL504_RS25430	COG3383	formate dehydrogenase (NAD+) activity
AL504_RS25450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL504_RS25455	COG0746	molybdenum cofactor guanylyltransferase activity
AL504_RS25460	COG0303	'Molybdopterin
AL504_RS25465	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL504_RS25470	COG0314	molybdopterin synthase activity
AL504_RS25480	COG0315	cyclic pyranopterin monophosphate synthase activity
AL504_RS25490	COG0412	Dienelactone hydrolase
AL504_RS25500	COG0678	peroxiredoxin activity
AL504_RS25510	COG0697	spore germination
AL504_RS25555	COG0667	Aldo Keto reductase
AL504_RS25560	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL504_RS25565	COG4535	Mg2 and Co2 transporter CorC
AL504_RS25570	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL504_RS25575	COG1702	phosphate starvation-inducible protein PhoH
AL504_RS25580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL504_RS25590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL504_RS25610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_RS25615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_RS25620	COG1862	Preprotein translocase
AL504_RS25625	COG3077	Addiction module antitoxin, RelB DinJ family
AL504_RS25635	COG0343	queuine tRNA-ribosyltransferase activity
AL504_RS25640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL504_RS25650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_RS25665	COG2027	D-alanyl-D-alanine carboxypeptidase
AL504_RS25670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL504_RS25675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL504_RS25675	COG1648	precorrin-2 dehydrogenase activity
AL504_RS25680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS25690	COG1116	anion transmembrane transporter activity
AL504_RS25700	COG4575	ribosome binding
AL504_RS25715	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL504_RS25720	COG0741	lytic transglycosylase activity
AL504_RS25730	COG0436	Aminotransferase
AL504_RS25740	COG0281	malic enzyme
AL504_RS25740	COG0280	phosphate acetyltransferase
AL504_RS25750	COG2732	(Barnase) inhibitor
AL504_RS25755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL504_RS25765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL504_RS25770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL504_RS25775	COG0126	phosphoglycerate kinase activity
AL504_RS25790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL504_RS25795	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL504_RS25815	COG0625	glutathione transferase activity
AL504_RS25835	COG0789	Transcriptional regulator
AL504_RS25850	COG0306	phosphate transporter
AL504_RS25860	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL504_RS25870	COG0739	heme binding
AL504_RS25880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL504_RS25890	COG0640	Transcriptional regulator
AL504_RS25900	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL504_RS25905	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL504_RS25910	COG3639	organic phosphonate transmembrane transporter activity
AL504_RS25925	COG0405	Gamma-glutamyltransferase
AL504_RS25930	COG0583	DNA-binding transcription factor activity
AL504_RS25935	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL504_RS25940	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL504_RS25945	COG3454	Phosphonate metabolism
AL504_RS25950	COG2188	Transcriptional regulator
AL504_RS25955	COG3624	Phosphonate C-P lyase system protein PhnG
AL504_RS25960	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL504_RS25965	COG3626	phosphonate metabolism
AL504_RS25970	COG3627	carbon phosphorus lyase activity
AL504_RS25975	COG4107	phosphonate C-P lyase system protein PhnK
AL504_RS25980	COG4778	phosphonate C-P lyase system protein PhnL
AL504_RS25985	COG3454	Phosphonate metabolism
AL504_RS26000	COG1301	dicarboxylic acid transport
AL504_RS26020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL504_RS26025	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL504_RS26030	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL504_RS26035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL504_RS26040	COG0009	L-threonylcarbamoyladenylate synthase
AL504_RS26045	COG1414	Transcriptional regulator
AL504_RS26050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_RS26065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS26070	COG1414	Transcriptional regulator
AL504_RS26075	COG0010	Belongs to the arginase family
AL504_RS26085	COG0765	amino acid transport
AL504_RS26090	COG1126	abc transporter atp-binding protein
AL504_RS26095	COG0028	Belongs to the TPP enzyme family
AL504_RS26110	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS26140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL504_RS26160	COG2030	dehydratase
AL504_RS26185	COG0028	Belongs to the TPP enzyme family
AL504_RS26190	COG0583	DNA-binding transcription factor activity
AL504_RS26195	COG4974	Belongs to the 'phage' integrase family
AL504_RS26200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL504_RS26220	COG1686	Belongs to the peptidase S11 family
AL504_RS26240	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS26245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_RS26255	COG1024	Enoyl-CoA hydratase
AL504_RS26260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS26275	COG2070	2-Nitropropane dioxygenase
AL504_RS26290	COG1074	ATP-dependent DNA helicase activity
AL504_RS26315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL504_RS26330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_RS26335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS26345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS26360	COG0745	RESPONSE REGULATOR receiver
AL504_RS26380	COG0505	Belongs to the CarA family
AL504_RS26385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL504_RS26400	COG0406	alpha-ribazole phosphatase activity
AL504_RS26410	COG3842	ATPase activity
AL504_RS26430	COG2233	PERMEase
AL504_RS26435	COG0840	transmembrane signaling receptor activity
AL504_RS26440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL504_RS26445	COG1534	Rna-binding protein
AL504_RS26450	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL504_RS26455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL504_RS26465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL504_RS26500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL504_RS26505	COG2814	Major facilitator Superfamily
AL504_RS26515	COG0477	Major facilitator Superfamily
AL504_RS26520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS26535	COG2841	Protein conserved in bacteria
AL504_RS26550	COG1595	DNA-templated transcription, initiation
AL504_RS26560	COG0583	DNA-binding transcription factor activity
AL504_RS26565	COG2207	Transcriptional regulator
AL504_RS26570	COG0667	Aldo Keto reductase
AL504_RS26595	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL504_RS26600	COG0500	methyltransferase
AL504_RS26630	COG0517	IMP dehydrogenase activity
AL504_RS26640	COG3938	Belongs to the proline racemase family
AL504_RS26645	COG1177	transmembrane transport
AL504_RS26655	COG3842	ATPase activity
AL504_RS26715	COG3264	Mechanosensitive ion channel
AL504_RS26715	COG1511	domain protein
AL504_RS26720	COG0583	DNA-binding transcription factor activity
AL504_RS26725	COG0427	acetyl-CoA hydrolase
AL504_RS26730	COG0583	DNA-binding transcription factor activity
AL504_RS26770	COG0235	Class ii aldolase
AL504_RS26780	COG0583	DNA-binding transcription factor activity
AL504_RS26795	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS26805	COG0477	Major facilitator Superfamily
AL504_RS26815	COG0154	amidase activity
AL504_RS26835	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL504_RS26850	COG0495	leucyl-tRNA aminoacylation
AL504_RS26855	COG2814	Major facilitator Superfamily
AL504_RS26860	COG1846	Transcriptional regulator
AL504_RS26870	COG1686	Belongs to the peptidase S11 family
AL504_RS26905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL504_RS26910	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL504_RS26915	COG2814	Major facilitator Superfamily
AL504_RS26920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_RS26930	COG4176	ABC-type proline glycine betaine transport system permease component
AL504_RS26950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS26955	COG2706	6-phosphogluconolactonase activity
AL504_RS26960	COG4214	carbohydrate transport
AL504_RS26965	COG1129	ABC transporter
AL504_RS26970	COG4213	ABC transporter substrate-binding protein
AL504_RS26980	COG0183	Belongs to the thiolase family
AL504_RS26990	COG1802	Transcriptional regulator
AL504_RS27000	COG1024	Enoyl-CoA hydratase
AL504_RS27005	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS27015	COG0667	Aldo Keto reductase
AL504_RS27025	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL504_RS27040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS27050	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL504_RS27070	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AL504_RS27075	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL504_RS27080	COG4149	molybdate abc transporter
AL504_RS27085	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL504_RS27110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_RS27115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_RS27125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL504_RS27130	COG0736	holo-[acyl-carrier-protein] synthase activity
AL504_RS27145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL504_RS27155	COG0473	3-isopropylmalate dehydrogenase activity
AL504_RS27160	COG0583	DNA-binding transcription factor activity
AL504_RS27165	COG1858	cytochrome C peroxidase
AL504_RS27170	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL504_RS27170	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL504_RS27175	COG2224	Isocitrate lyase
AL504_RS27190	COG4106	trans-aconitate 2-methyltransferase activity
AL504_RS27190	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL504_RS27200	COG0156	8-amino-7-oxononanoate synthase activity
AL504_RS27220	COG3278	Belongs to the heme-copper respiratory oxidase family
AL504_RS27240	COG0348	domain, Protein
AL504_RS27260	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS27265	COG1126	abc transporter atp-binding protein
AL504_RS27270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS27280	COG0765	amino acid transport
AL504_RS27285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_RS27320	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL504_RS27330	COG0438	transferase activity, transferring glycosyl groups
AL504_RS27345	COG1538	Outer membrane efflux protein
AL504_RS27350	COG1566	PFAM secretion protein HlyD family protein
AL504_RS27365	COG0583	DNA-binding transcription factor activity
AL504_RS27370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_RS27375	COG0586	Pfam SNARE associated Golgi protein
AL504_RS27380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_RS27395	COG4608	Belongs to the ABC transporter superfamily
AL504_RS27400	COG0444	Belongs to the ABC transporter superfamily
AL504_RS27405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS27410	COG0601	transmembrane transport
AL504_RS27415	COG0583	DNA-binding transcription factor activity
AL504_RS27420	COG0300	oxidoreductase activity
AL504_RS27425	COG1764	response to oxidative stress
AL504_RS27430	COG2205	protein histidine kinase activity
AL504_RS27455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_RS27470	COG1802	Transcriptional regulator
AL504_RS27485	COG1595	DNA-templated transcription, initiation
AL504_RS27505	COG2084	Dehydrogenase
AL504_RS27515	COG1917	Cupin 2, conserved barrel domain protein
AL504_RS27515	COG2207	Transcriptional regulator
AL504_RS27525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS27565	COG1280	lysine exporter protein (LysE YggA)
AL504_RS27570	COG1522	sequence-specific DNA binding
AL504_RS27590	COG1280	lysine exporter protein (LysE YggA)
AL504_RS27600	COG0745	RESPONSE REGULATOR receiver
AL504_RS27615	COG4774	siderophore transport
AL504_RS27620	COG3712	iron ion homeostasis
AL504_RS27625	COG1595	DNA-templated transcription, initiation
AL504_RS27630	COG0840	transmembrane signaling receptor activity
AL504_RS27635	COG3121	Chaperone
AL504_RS27640	COG3188	usher protein
AL504_RS27660	COG0642	Histidine kinase
AL504_RS27665	COG1475	DNA binding
AL504_RS27675	COG3969	phosphoadenosine phosphosulfate
AL504_RS27680	COG1971	Probably functions as a manganese efflux pump
AL504_RS27685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_RS27740	COG2321	neutral zinc metallopeptidase
AL504_RS27745	COG0009	L-threonylcarbamoyladenylate synthase
AL504_RS27750	COG1994	Peptidase M50
AL504_RS27755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_RS27760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL504_RS27770	COG2850	peptidyl-arginine hydroxylation
AL504_RS27775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL504_RS27810	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL504_RS27820	COG0583	DNA-binding transcription factor activity
AL504_RS27845	COG2311	Membrane
AL504_RS27865	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS27870	COG0583	DNA-binding transcription factor activity
AL504_RS27880	COG3360	Dodecin
AL504_RS27915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_RS27920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS27925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS27965	COG0668	transmembrane transport
AL504_RS27985	COG0583	DNA-binding transcription factor activity
AL504_RS28005	COG0483	inositol monophosphate 1-phosphatase activity
AL504_RS28010	COG4804	nuclease activity
AL504_RS28015	COG1477	protein flavinylation
AL504_RS28025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AL504_RS28040	COG4263	nitrous-oxide reductase activity
AL504_RS28055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL504_RS28060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL504_RS28070	COG1253	flavin adenine dinucleotide binding
AL504_RS28075	COG1968	undecaprenyl-diphosphatase activity
AL504_RS28080	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL504_RS28095	COG0215	cysteine-tRNA ligase activity
AL504_RS28105	COG0825	malonyl-CoA metabolic process
AL504_RS28115	COG0527	aspartate kinase activity
AL504_RS28130	COG0348	domain, Protein
AL504_RS28150	COG3278	Belongs to the heme-copper respiratory oxidase family
AL504_RS28165	COG3258	Cytochrome c
AL504_RS28170	COG2863	cytochrome
AL504_RS28175	COG0784	Response regulator, receiver
AL504_RS28175	COG2205	protein histidine kinase activity
AL504_RS28180	COG2200	EAL domain
AL504_RS28185	COG0784	Response regulator, receiver
AL504_RS28185	COG2205	protein histidine kinase activity
AL504_RS28190	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AL504_RS28200	COG1309	transcriptional regulator
AL504_RS28205	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL504_RS28245	COG0583	DNA-binding transcription factor activity
AL504_RS28270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL504_RS28280	COG1414	Transcriptional regulator
AL504_RS28290	COG1024	Enoyl-CoA hydratase
AL504_RS28295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL504_RS28300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_RS28310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL504_RS28325	COG1132	(ABC) transporter
AL504_RS28335	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS28345	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS28360	COG0183	Belongs to the thiolase family
AL504_RS28365	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS28365	COG1024	Enoyl-CoA hydratase
AL504_RS28375	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS28375	COG1024	Enoyl-CoA hydratase
AL504_RS28385	COG1960	acyl-CoA dehydrogenase activity
AL504_RS28390	COG1309	transcriptional regulator
AL504_RS28400	COG2197	response regulator
AL504_RS28405	COG2197	response regulator
AL504_RS28410	COG0297	glycogen (starch) synthase activity
AL504_RS28415	COG0110	maltose O-acetyltransferase activity
AL504_RS28420	COG0463	Glycosyl transferase, family 2
AL504_RS28445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_RS28490	COG0166	Belongs to the GPI family
AL504_RS28495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL504_RS28500	COG1045	serine acetyltransferase
AL504_RS28505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL504_RS28520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_RS28540	COG0598	Magnesium transport protein CorA
AL504_RS28555	COG0601	transmembrane transport
AL504_RS28560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS28565	COG4172	Belongs to the ABC transporter superfamily
AL504_RS28575	COG1846	Transcriptional regulator
AL504_RS28620	COG4964	Belongs to the GSP D family
AL504_RS28675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL504_RS28690	COG3384	dioxygenase
AL504_RS28695	COG0583	DNA-binding transcription factor activity
AL504_RS28705	COG2814	Major facilitator Superfamily
AL504_RS28710	COG1566	PFAM secretion protein HlyD family protein
AL504_RS28730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL504_RS28750	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS28755	COG3321	synthase
AL504_RS28755	COG0604	alcohol dehydrogenase
AL504_RS28755	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS28770	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_RS28780	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS28785	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS28790	COG3246	L-lysine catabolic process to acetate
AL504_RS28795	COG0371	Dehydrogenase
AL504_RS28800	COG1802	Transcriptional regulator
AL504_RS28805	COG3959	Transketolase, thiamine diphosphate binding domain
AL504_RS28810	COG3958	Transketolase
AL504_RS28815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL504_RS28825	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_RS28830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS28840	COG0765	amino acid transport
AL504_RS28850	COG2721	sulfolactate sulfo-lyase activity
AL504_RS28860	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS28865	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_RS28870	COG1414	Transcriptional regulator
AL504_RS28890	COG0596	Alpha beta hydrolase
AL504_RS28910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL504_RS28920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_RS28925	COG1120	ATPase activity
AL504_RS28940	COG4771	TonB-dependent receptor
AL504_RS28985	COG0784	Response regulator, receiver
AL504_RS28985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS28985	COG2198	Histidine kinase
AL504_RS28985	COG2205	protein histidine kinase activity
AL504_RS28990	COG0477	Major facilitator Superfamily
AL504_RS29000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_RS29010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_RS29030	COG1113	amino acid transport
AL504_RS29040	COG1640	4-alpha-glucanotransferase
AL504_RS29045	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL504_RS29055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL504_RS29060	COG0366	Alpha amylase catalytic
AL504_RS29065	COG0366	Alpha amylase catalytic
AL504_RS29070	COG0297	glycogen (starch) synthase activity
AL504_RS29075	COG0392	lysyltransferase activity
AL504_RS29080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_RS29085	COG3568	Endonuclease Exonuclease Phosphatase
AL504_RS29090	COG0387	Pfam Sodium calcium exchanger
AL504_RS29105	COG3685	Protein conserved in bacteria
AL504_RS29115	COG0166	Belongs to the GPI family
AL504_RS29125	COG0668	transmembrane transport
AL504_RS29195	COG1064	alcohol dehydrogenase
AL504_RS29210	COG1850	ribulose-bisphosphate carboxylase activity
AL504_RS29220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_RS29225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS29230	COG1609	Transcriptional regulator
AL504_RS29240	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS29245	COG0596	Alpha beta hydrolase
AL504_RS29270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL504_RS29285	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29300	COG1396	sequence-specific DNA binding
AL504_RS29390	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AL504_RS29395	COG1116	anion transmembrane transporter activity
AL504_RS29400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_RS29405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_RS29405	COG1116	anion transmembrane transporter activity
AL504_RS29410	COG2197	response regulator
AL504_RS29420	COG1131	(ABC) transporter
AL504_RS29425	COG0842	Transport permease protein
AL504_RS29440	COG0183	Belongs to the thiolase family
AL504_RS29465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_RS29470	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_RS29480	COG0604	alcohol dehydrogenase
AL504_RS29480	COG3321	synthase
AL504_RS29495	COG4638	Rieske (2fe-2S)
AL504_RS29525	COG1272	protein, Hemolysin III
AL504_RS29555	COG2169	Transcriptional regulator
AL504_RS29575	COG0583	DNA-binding transcription factor activity
AL504_RS29585	COG4172	Belongs to the ABC transporter superfamily
AL504_RS29590	COG0402	S-adenosylhomocysteine deaminase activity
AL504_RS29595	COG0747	negative chemotaxis
AL504_RS29600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS29610	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29620	COG2814	Major facilitator Superfamily
AL504_RS29625	COG0583	DNA-binding transcription factor activity
AL504_RS29635	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL504_RS29710	COG4126	flavin adenine dinucleotide binding
AL504_RS29725	COG2837	iron assimilation
AL504_RS29760	COG0583	DNA-binding transcription factor activity
AL504_RS29765	COG2814	Major facilitator Superfamily
AL504_RS29770	COG0583	DNA-binding transcription factor activity
AL504_RS29785	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_RS29800	COG2814	Major facilitator Superfamily
AL504_RS29810	COG1464	Belongs to the NlpA lipoprotein family
AL504_RS29815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL504_RS29820	COG2011	ABC-type metal ion transport system permease component
AL504_RS29855	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29875	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AL504_RS29880	COG0454	-acetyltransferase
AL504_RS29880	COG0456	acetyltransferase
AL504_RS29890	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29895	COG1473	amidohydrolase
AL504_RS29910	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS29915	COG2272	Belongs to the type-B carboxylesterase lipase family
AL504_RS29925	COG0583	DNA-binding transcription factor activity
AL504_RS29940	COG2951	lytic endotransglycosylase activity
AL504_RS29950	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS29960	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_RS29970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_RS29995	COG1522	sequence-specific DNA binding
AL504_RS30010	COG3706	GGDEF domain
AL504_RS30045	COG0625	glutathione transferase activity
AL504_RS30060	COG3530	Putative quorum-sensing-regulated virulence factor
AL504_RS30070	COG2814	Major facilitator Superfamily
AL504_RS30105	COG0443	Heat shock 70 kDa protein
AL504_RS30110	COG0583	DNA-binding transcription factor activity
AL504_RS30130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_RS30135	COG0477	Major facilitator Superfamily
AL504_RS30145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL504_RS30155	COG0542	response to heat
AL504_RS30180	COG5441	Belongs to the UPF0261 family
AL504_RS30185	COG5564	TIM-barrel signal transduction protein
AL504_RS30200	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_RS30215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL504_RS30225	COG1562	ergosterol biosynthetic process
AL504_RS30235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL504_RS30240	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS30250	COG3971	2-oxopent-4-enoate hydratase activity
AL504_RS30265	COG1012	belongs to the aldehyde dehydrogenase family
AL504_RS30270	COG3384	dioxygenase
AL504_RS30300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_RS30310	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS30320	COG2186	Transcriptional regulator
AL504_RS30325	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_RS30330	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_RS30345	COG0583	DNA-binding transcription factor activity
AL504_RS30350	COG0268	Binds directly to 16S ribosomal RNA
AL504_RS30360	COG0728	peptidoglycan biosynthetic process
AL504_RS30370	COG0563	adenylate kinase activity
AL504_RS30375	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL504_RS30380	COG2835	tetraacyldisaccharide 4'-kinase activity
AL504_RS30390	COG1663	tetraacyldisaccharide 4'-kinase activity
AL504_RS30400	COG0811	peptide transport
AL504_RS30405	COG1570	exodeoxyribonuclease VII activity
AL504_RS30415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL504_RS30425	COG0038	chloride channel
AL504_RS30430	COG0183	Belongs to the thiolase family
AL504_RS30440	COG1278	Cold shock
AL504_RS30445	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL504_RS30450	COG2373	Large extracellular alpha-helical protein
AL504_RS30455	COG4953	penicillin-binding protein 1C
AL504_RS30465	COG2995	paraquat-inducible protein a
AL504_RS30470	COG3008	intermembrane lipid transfer
AL504_RS30480	COG0506	proline dehydrogenase activity
AL504_RS30480	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL504_RS30480	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL504_RS30520	COG2271	Major facilitator Superfamily
AL504_RS30540	COG1289	transmembrane transporter activity
AL504_RS30550	COG1566	PFAM secretion protein HlyD family protein
AL504_RS30565	COG0625	glutathione transferase activity
AL504_RS30580	COG1764	response to oxidative stress
AL504_RS30585	COG2423	ornithine cyclodeaminase activity
AL504_RS30595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_RS30600	COG0765	amino acid transport
AL504_RS30605	COG0765	amino acid transport
AL504_RS30610	COG1126	abc transporter atp-binding protein
AL504_RS30615	COG1902	pentaerythritol trinitrate reductase activity
AL504_RS30670	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL504_RS30675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL504_RS30680	COG0196	riboflavin kinase activity
AL504_RS30685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL504_RS30690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL504_RS30690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL504_RS30705	COG0210	DNA helicase
AL504_RS30715	COG1858	cytochrome C peroxidase
AL504_RS30720	COG4771	TonB-dependent receptor
AL504_RS30725	COG4771	TonB-dependent receptor
AL504_RS30730	COG4771	TonB-dependent receptor
AL504_RS30745	COG0488	(ABC) transporter
AL504_RS30750	COG2890	protein-(glutamine-N5) methyltransferase activity
AL504_RS30760	COG2171	N-acyltransferase activity
AL504_RS30825	COG1403	HNH endonuclease
AL504_RS30835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL504_RS30905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL504_RS30935	COG0740	serine-type endopeptidase activity
AL504_RS31110	COG3038	cytochrome b561
AL504_RS31115	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL504_RS31155	COG0583	DNA-binding transcription factor activity
AL504_RS31165	COG0251	oxidation-reduction process
AL504_RS31190	COG1278	Cold shock
AL504_RS31200	COG1278	Cold shock
AL504_RS31210	COG0501	Belongs to the peptidase M48B family
AL504_RS31215	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL504_RS31220	COG0740	serine-type endopeptidase activity
AL504_RS31230	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL504_RS31235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL504_RS31245	COG0556	nucleotide-excision repair
AL504_RS31250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL504_RS31260	COG1104	cysteine desulfurase activity
AL504_RS31265	COG0822	iron-sulfur transferase activity
AL504_RS31270	COG0316	Belongs to the HesB IscA family
AL504_RS31275	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL504_RS31280	COG0443	Heat shock 70 kDa protein
AL504_RS31285	COG0633	Ferredoxin
AL504_RS31290	COG2975	iron-sulfur cluster assembly
AL504_RS31295	COG1803	Methylglyoxal synthase
AL504_RS31305	COG1024	Enoyl-CoA hydratase
AL504_RS31335	COG1022	Amp-dependent synthetase and ligase
AL504_RS31345	COG1309	transcriptional regulator
AL504_RS31375	COG3135	benzoate transporter
AL504_RS31390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL504_RS31395	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_RS31405	COG2271	Major facilitator Superfamily