locus-tag	class	description
AL520_RS00010	COG1522	sequence-specific DNA binding
AL520_RS00015	COG4772	TonB-dependent receptor
AL520_RS00030	COG2354	Protein conserved in bacteria
AL520_RS00035	COG3813	Protein conserved in bacteria
AL520_RS00055	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS00060	COG2851	Citrate transporter
AL520_RS00070	COG0642	Histidine kinase
AL520_RS00080	COG4566	intracellular signal transduction
AL520_RS00085	COG4191	Histidine kinase
AL520_RS00115	COG3712	iron ion homeostasis
AL520_RS00120	COG1595	DNA-templated transcription, initiation
AL520_RS00175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL520_RS00180	COG0149	triose-phosphate isomerase activity
AL520_RS00200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_RS00210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS00240	COG2819	hydrolase of the alpha beta superfamily
AL520_RS00250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL520_RS00260	COG1185	polyribonucleotide nucleotidyltransferase activity
AL520_RS00265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL520_RS00275	COG1183	phosphatidylcholine synthase activity
AL520_RS00280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL520_RS00285	COG0440	acetolactate synthase activity
AL520_RS00290	COG0028	Belongs to the TPP enzyme family
AL520_RS00295	COG1289	transmembrane transporter activity
AL520_RS00300	COG3022	response to hydroperoxide
AL520_RS00305	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS00325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_RS00365	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL520_RS00370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL520_RS00375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL520_RS00390	COG0601	transmembrane transport
AL520_RS00410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL520_RS00410	COG0517	IMP dehydrogenase activity
AL520_RS00415	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_RS00420	COG0251	oxidation-reduction process
AL520_RS00425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL520_RS00430	COG1674	ftsk spoiiie
AL520_RS00435	COG0492	ferredoxin-NADP+ reductase activity
AL520_RS00440	COG1193	negative regulation of DNA recombination
AL520_RS00450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL520_RS00465	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AL520_RS00470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL520_RS00475	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL520_RS00480	COG2205	protein histidine kinase activity
AL520_RS00485	COG0745	RESPONSE REGULATOR receiver
AL520_RS00505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_RS00510	COG3307	-O-antigen
AL520_RS00540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL520_RS00565	COG0612	Peptidase, M16
AL520_RS00575	COG0484	heat shock protein binding
AL520_RS00580	COG0443	Heat shock 70 kDa protein
AL520_RS00590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL520_RS00600	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL520_RS00605	COG1420	regulation of RNA biosynthetic process
AL520_RS00615	COG0497	DNA recombination
AL520_RS00620	COG0735	belongs to the Fur family
AL520_RS00625	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL520_RS00645	COG0582	viral genome integration into host DNA
AL520_RS00665	COG0300	oxidoreductase activity
AL520_RS00670	COG0583	DNA-binding transcription factor activity
AL520_RS00695	COG1309	transcriptional regulator
AL520_RS00700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_RS00705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL520_RS00730	COG4372	Transposase
AL520_RS00740	COG1309	transcriptional regulator
AL520_RS00745	COG4221	oxidoreductase activity
AL520_RS00750	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS00755	COG0657	acetylesterase activity
AL520_RS00875	COG3246	L-lysine catabolic process to acetate
AL520_RS01010	COG2814	Major facilitator Superfamily
AL520_RS01020	COG0583	DNA-binding transcription factor activity
AL520_RS01025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL520_RS01080	COG1192	Involved in chromosome partitioning
AL520_RS01095	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS01100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS01105	COG0583	DNA-binding transcription factor activity
AL520_RS01175	COG0583	DNA-binding transcription factor activity
AL520_RS01190	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL520_RS01195	COG0167	dihydroorotate dehydrogenase activity
AL520_RS01210	COG1414	Transcriptional regulator
AL520_RS01215	COG1058	Belongs to the CinA family
AL520_RS01215	COG1546	Belongs to the CinA family
AL520_RS01230	COG0513	Belongs to the DEAD box helicase family
AL520_RS01245	COG2814	Major facilitator Superfamily
AL520_RS01285	COG4783	chaperone-mediated protein folding
AL520_RS01300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS01305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL520_RS01320	COG0006	proline dipeptidase activity
AL520_RS01330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_RS01355	COG0632	four-way junction helicase activity
AL520_RS01360	COG1090	epimerase
AL520_RS01370	COG2255	four-way junction helicase activity
AL520_RS01390	COG0514	ATP-dependent DNA helicase (RecQ)
AL520_RS01395	COG1294	oxidase, subunit
AL520_RS01405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL520_RS01415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS01420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_RS01425	COG1414	Transcriptional regulator
AL520_RS01430	COG0850	regulation of cytokinetic process
AL520_RS01435	COG2894	cell division
AL520_RS01440	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL520_RS01465	COG0488	(ABC) transporter
AL520_RS01470	COG2746	aminoglycoside 3-N-acetyltransferase activity
AL520_RS01490	COG4608	Belongs to the ABC transporter superfamily
AL520_RS01495	COG0444	Belongs to the ABC transporter superfamily
AL520_RS01500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS01505	COG0601	transmembrane transport
AL520_RS01510	COG0747	negative chemotaxis
AL520_RS01535	COG4638	Rieske (2fe-2S)
AL520_RS01540	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL520_RS01560	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL520_RS01565	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS01590	COG0463	Glycosyl transferase, family 2
AL520_RS01590	COG1216	Glycosyl transferase, family 2
AL520_RS01605	COG0800	Aldolase
AL520_RS01615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL520_RS01650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL520_RS01655	COG1538	Outer membrane efflux protein
AL520_RS01660	COG1136	(ABC) transporter
AL520_RS01660	COG0577	efflux transmembrane transporter activity
AL520_RS01665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_RS01680	COG0259	pyridoxamine-phosphate oxidase activity
AL520_RS01690	COG0579	oxidoreductase
AL520_RS01700	COG0583	DNA-binding transcription factor activity
AL520_RS01705	COG1960	acyl-CoA dehydrogenase activity
AL520_RS01715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS01720	COG0531	amino acid
AL520_RS01725	COG0405	Gamma-glutamyltransferase
AL520_RS01735	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS01745	COG0114	fumarate hydratase activity
AL520_RS01750	COG0802	atpase or kinase
AL520_RS01755	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL520_RS01765	COG0586	Pfam SNARE associated Golgi protein
AL520_RS01770	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL520_RS01775	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL520_RS01785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL520_RS01800	COG0617	tRNA 3'-terminal CCA addition
AL520_RS01810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL520_RS01815	COG2301	Belongs to the HpcH HpaI aldolase family
AL520_RS01825	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AL520_RS01835	COG1024	Enoyl-CoA hydratase
AL520_RS01845	COG1960	acyl-CoA dehydrogenase activity
AL520_RS01855	COG0183	Belongs to the thiolase family
AL520_RS01860	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS01870	COG2070	2-Nitropropane dioxygenase
AL520_RS01890	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS01895	COG2030	dehydratase
AL520_RS01900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS01915	COG1024	Enoyl-CoA hydratase
AL520_RS01920	COG0752	glycyl-tRNA synthetase alpha subunit
AL520_RS01925	COG0751	glycine-tRNA ligase activity
AL520_RS01930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL520_RS01935	COG0204	Acyl-transferase
AL520_RS01955	COG0242	peptide deformylase activity
AL520_RS01965	COG0700	Nucleoside recognition
AL520_RS01970	COG0469	pyruvate kinase activity
AL520_RS01975	COG1929	Belongs to the glycerate kinase type-1 family
AL520_RS01980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL520_RS01985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_RS02000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL520_RS02025	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL520_RS02055	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS02070	COG2982	Protein involved in outer membrane biogenesis
AL520_RS02075	COG1368	sulfuric ester hydrolase activity
AL520_RS02080	COG2818	Glycosylase
AL520_RS02100	COG0735	belongs to the Fur family
AL520_RS02115	COG0840	transmembrane signaling receptor activity
AL520_RS02175	COG2011	ABC-type metal ion transport system permease component
AL520_RS02180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL520_RS02185	COG1501	Belongs to the glycosyl hydrolase 31 family
AL520_RS02190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS02190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL520_RS02195	COG0483	inositol monophosphate 1-phosphatase activity
AL520_RS02200	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS02205	COG1473	amidohydrolase
AL520_RS02210	COG0583	DNA-binding transcription factor activity
AL520_RS02215	COG2855	membrane
AL520_RS02225	COG2239	Acts as a magnesium transporter
AL520_RS02240	COG1522	sequence-specific DNA binding
AL520_RS02245	COG0300	oxidoreductase activity
AL520_RS02255	COG0028	Belongs to the TPP enzyme family
AL520_RS02260	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS02275	COG0653	protein targeting
AL520_RS02280	COG0739	heme binding
AL520_RS02290	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL520_RS02295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL520_RS02305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL520_RS02310	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL520_RS02315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL520_RS02320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL520_RS02330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL520_RS02335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL520_RS02340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL520_RS02350	COG3116	cell division
AL520_RS02355	COG0275	rRNA processing
AL520_RS02360	COG2001	Belongs to the MraZ family
AL520_RS02370	COG0488	(ABC) transporter
AL520_RS02375	COG0418	dihydroorotase activity
AL520_RS02380	COG1473	amidohydrolase
AL520_RS02420	COG1522	sequence-specific DNA binding
AL520_RS02430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL520_RS02435	COG4654	Cytochrome c, class I
AL520_RS02440	COG0129	dihydroxy-acid dehydratase activity
AL520_RS02480	COG0405	Gamma-glutamyltransferase
AL520_RS02485	COG2084	Dehydrogenase
AL520_RS02500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_RS02530	COG0442	prolyl-tRNA aminoacylation
AL520_RS02535	COG0824	Thioesterase
AL520_RS02540	COG0811	peptide transport
AL520_RS02545	COG0848	biopolymer transport protein
AL520_RS02555	COG0823	Involved in the tonB-independent uptake of proteins
AL520_RS02570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_RS02575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL520_RS02590	COG1522	sequence-specific DNA binding
AL520_RS02600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL520_RS02615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS02620	COG0697	spore germination
AL520_RS02635	COG1380	Effector of murein hydrolase LrgA
AL520_RS02640	COG0583	DNA-binding transcription factor activity
AL520_RS02650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_RS02670	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_RS02690	COG0583	DNA-binding transcription factor activity
AL520_RS02705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL520_RS02710	COG0463	Glycosyl transferase, family 2
AL520_RS02720	COG0786	glutamate:sodium symporter activity
AL520_RS02735	COG1671	Belongs to the UPF0178 family
AL520_RS02755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_RS02765	COG0328	RNA-DNA hybrid ribonuclease activity
AL520_RS02770	COG2226	methyltransferase
AL520_RS02775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL520_RS02780	COG1388	LysM domain
AL520_RS02780	COG0741	lytic transglycosylase activity
AL520_RS02820	COG1366	Belongs to the anti-sigma-factor antagonist family
AL520_RS02825	COG2172	sigma factor antagonist activity
AL520_RS02830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL520_RS02840	COG2208	phosphoserine phosphatase activity
AL520_RS02840	COG2770	Histidine kinase
AL520_RS02870	COG4792	protein secretion
AL520_RS02875	COG4791	protein targeting
AL520_RS02880	COG4794	Type iii secretion
AL520_RS02885	COG4790	Type iii secretion
AL520_RS02890	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL520_RS02920	COG4669	(LipO)protein
AL520_RS02995	COG4789	Type iii secretion
AL520_RS03045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL520_RS03050	COG0456	acetyltransferase
AL520_RS03060	COG1942	4-Oxalocrotonate Tautomerase
AL520_RS03065	COG0583	DNA-binding transcription factor activity
AL520_RS03075	COG2719	SpoVR family
AL520_RS03080	COG2718	Belongs to the UPF0229 family
AL520_RS03085	COG2766	serine protein kinase
AL520_RS03100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL520_RS03100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL520_RS03115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL520_RS03120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL520_RS03125	COG1280	lysine exporter protein (LysE YggA)
AL520_RS03135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL520_RS03150	COG0316	Belongs to the HesB IscA family
AL520_RS03160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL520_RS03165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL520_RS03170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL520_RS03185	COG4177	L-phenylalanine transmembrane transporter activity
AL520_RS03190	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_RS03200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL520_RS03205	COG0312	modulator of DNA gyrase
AL520_RS03210	COG3028	Belongs to the UPF0307 family
AL520_RS03225	COG1116	anion transmembrane transporter activity
AL520_RS03230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS03235	COG1335	isochorismatase
AL520_RS03240	COG0045	succinate-CoA ligase (ADP-forming) activity
AL520_RS03240	COG1042	CoA-binding domain protein
AL520_RS03240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL520_RS03245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL520_RS03260	COG0583	DNA-binding transcription factor activity
AL520_RS03270	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS03275	COG1522	sequence-specific DNA binding
AL520_RS03305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL520_RS03310	COG1696	Membrane protein involved in D-alanine export
AL520_RS03335	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL520_RS03335	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL520_RS03345	COG2264	protein methyltransferase activity
AL520_RS03350	COG0439	Biotin carboxylase
AL520_RS03360	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL520_RS03365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_RS03370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL520_RS03375	COG3150	esterase
AL520_RS03380	COG0557	exoribonuclease II activity
AL520_RS03400	COG1175	transmembrane transport
AL520_RS03405	COG3842	ATPase activity
AL520_RS03415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL520_RS03420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL520_RS03430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL520_RS03435	COG1126	abc transporter atp-binding protein
AL520_RS03440	COG0765	amino acid transport
AL520_RS03450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS03455	COG0436	Aminotransferase
AL520_RS03460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL520_RS03470	COG3328	transposase activity
AL520_RS03490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL520_RS03495	COG1678	Uncharacterized ACR, COG1678
AL520_RS03510	COG0352	thiamine-phosphate diphosphorylase activity
AL520_RS03515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL520_RS03520	COG0741	lytic transglycosylase activity
AL520_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS03535	COG1335	isochorismatase
AL520_RS03540	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL520_RS03545	COG4638	Rieske (2fe-2S)
AL520_RS03585	COG1024	Enoyl-CoA hydratase
AL520_RS03590	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS03625	COG0410	ABC transporter
AL520_RS03660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL520_RS03670	COG2816	NAD+ diphosphatase activity
AL520_RS03680	COG3842	ATPase activity
AL520_RS03690	COG3833	ABC-type maltose transport systems, permease component
AL520_RS03705	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_RS03745	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL520_RS03750	COG0237	dephospho-CoA kinase activity
AL520_RS03770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL520_RS03775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL520_RS03785	COG0477	Major facilitator Superfamily
AL520_RS03820	COG0077	Prephenate dehydratase
AL520_RS03820	COG1605	Chorismate mutase
AL520_RS03830	COG2081	HI0933 family
AL520_RS03835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_RS03860	COG1126	abc transporter atp-binding protein
AL520_RS03865	COG0765	amino acid transport
AL520_RS03870	COG4597	amino acid ABC transporter
AL520_RS03875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS03880	COG2884	Cell division ATP-binding protein ftsE
AL520_RS03885	COG2177	Part of the ABC transporter FtsEX involved in
AL520_RS03910	COG1194	a g-specific adenine glycosylase
AL520_RS03925	COG0246	Mannitol dehydrogenase
AL520_RS03930	COG4948	Mandelate Racemase Muconate Lactonizing
AL520_RS03935	COG1126	abc transporter atp-binding protein
AL520_RS03940	COG0765	amino acid transport
AL520_RS03950	COG1063	alcohol dehydrogenase
AL520_RS03965	COG2186	Transcriptional regulator
AL520_RS03975	COG4771	TonB-dependent receptor
AL520_RS03980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL520_RS03985	COG2022	thiamine diphosphate biosynthetic process
AL520_RS03990	COG0351	phosphomethylpyrimidine kinase
AL520_RS03995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL520_RS04005	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL520_RS04015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL520_RS04030	COG2226	methyltransferase
AL520_RS04035	COG0745	RESPONSE REGULATOR receiver
AL520_RS04060	COG2132	Multicopper oxidase
AL520_RS04075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_RS04090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL520_RS04095	COG1984	allophanate hydrolase subunit 2
AL520_RS04105	COG1802	Transcriptional regulator
AL520_RS04110	COG2860	membrane
AL520_RS04120	COG2223	nitrite transmembrane transporter activity
AL520_RS04125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_RS04125	COG2813	Specifically methylates the guanine in position
AL520_RS04130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_RS04135	COG2188	Transcriptional regulator
AL520_RS04140	COG2721	sulfolactate sulfo-lyase activity
AL520_RS04145	COG2721	sulfolactate sulfo-lyase activity
AL520_RS04155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_RS04160	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL520_RS04200	COG2918	glutathione biosynthetic process
AL520_RS04210	COG2988	succinylglutamate desuccinylase activity
AL520_RS04220	COG0583	DNA-binding transcription factor activity
AL520_RS04230	COG1802	Transcriptional regulator
AL520_RS04245	COG1129	ABC transporter
AL520_RS04265	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL520_RS04280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS04285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL520_RS04290	COG1595	DNA-templated transcription, initiation
AL520_RS04300	COG0583	DNA-binding transcription factor activity
AL520_RS04305	COG1764	response to oxidative stress
AL520_RS04340	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_RS04355	COG1309	transcriptional regulator
AL520_RS04365	COG1024	Enoyl-CoA hydratase
AL520_RS04370	COG1024	Enoyl-CoA hydratase
AL520_RS04375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL520_RS04385	COG0747	negative chemotaxis
AL520_RS04390	COG0583	DNA-binding transcription factor activity
AL520_RS04400	COG2988	succinylglutamate desuccinylase activity
AL520_RS04405	COG0747	negative chemotaxis
AL520_RS04410	COG0601	transmembrane transport
AL520_RS04420	COG0444	Belongs to the ABC transporter superfamily
AL520_RS04425	COG4608	Belongs to the ABC transporter superfamily
AL520_RS04435	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL520_RS04445	COG2171	N-acyltransferase activity
AL520_RS04455	COG4221	oxidoreductase activity
AL520_RS04460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL520_RS04475	COG0210	DNA helicase
AL520_RS04480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL520_RS04485	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL520_RS04495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL520_RS04505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL520_RS04510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL520_RS04515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL520_RS04530	COG0356	it plays a direct role in the translocation of protons across the membrane
AL520_RS04545	COG1024	Enoyl-CoA hydratase
AL520_RS04550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL520_RS04560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL520_RS04575	COG0583	DNA-binding transcription factor activity
AL520_RS04580	COG3473	Maleate cis-trans isomerase
AL520_RS04585	COG0583	DNA-binding transcription factor activity
AL520_RS04590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_RS04605	COG0037	tRNA processing
AL520_RS04610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_RS04620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_RS04630	COG2967	ApaG domain
AL520_RS04635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL520_RS04640	COG0546	phosphoglycolate phosphatase activity
AL520_RS04650	COG0512	Glutamine amidotransferase of anthranilate synthase
AL520_RS04655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL520_RS04660	COG0134	indole-3-glycerol-phosphate synthase activity
AL520_RS04665	COG3284	Transcriptional regulator
AL520_RS04670	COG1012	belongs to the aldehyde dehydrogenase family
AL520_RS04700	COG0709	Synthesizes selenophosphate from selenide and ATP
AL520_RS04705	COG1305	Transglutaminase-like
AL520_RS04710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_RS04715	COG1215	transferase activity, transferring glycosyl groups
AL520_RS04725	COG3276	selenocysteine insertion sequence binding
AL520_RS04740	COG2864	formate dehydrogenase
AL520_RS04745	COG0437	4 iron, 4 sulfur cluster binding
AL520_RS04750	COG3383	formate dehydrogenase (NAD+) activity
AL520_RS04750	COG0243	molybdopterin cofactor binding
AL520_RS04755	COG3383	formate dehydrogenase (NAD+) activity
AL520_RS04755	COG0243	molybdopterin cofactor binding
AL520_RS04765	COG1607	acyl-coa hydrolase
AL520_RS04770	COG2801	Transposase and inactivated derivatives
AL520_RS04770	COG3415	Transposase
AL520_RS04790	COG3585	molybdate ion transport
AL520_RS04795	COG1116	anion transmembrane transporter activity
AL520_RS04800	COG1464	Belongs to the NlpA lipoprotein family
AL520_RS04805	COG2011	ABC-type metal ion transport system permease component
AL520_RS04820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS04825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL520_RS04830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_RS04835	COG0431	NADPH-dependent FMN reductase
AL520_RS04840	COG1464	Belongs to the NlpA lipoprotein family
AL520_RS04845	COG3328	transposase activity
AL520_RS04870	COG0747	negative chemotaxis
AL520_RS04880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS04885	COG4172	Belongs to the ABC transporter superfamily
AL520_RS04890	COG0589	response to stress
AL520_RS04905	COG1012	belongs to the aldehyde dehydrogenase family
AL520_RS04910	COG3069	C4-dicarboxylate transmembrane transporter activity
AL520_RS04920	COG1802	Transcriptional regulator
AL520_RS04980	COG3188	usher protein
AL520_RS04995	COG2814	Major facilitator Superfamily
AL520_RS05000	COG0840	transmembrane signaling receptor activity
AL520_RS05020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL520_RS05025	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL520_RS05050	COG0737	Belongs to the 5'-nucleotidase family
AL520_RS05095	COG0463	Glycosyl transferase, family 2
AL520_RS05100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL520_RS05120	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL520_RS05125	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL520_RS05130	COG5001	Diguanylate cyclase
AL520_RS05135	COG2423	ornithine cyclodeaminase activity
AL520_RS05140	COG0583	DNA-binding transcription factor activity
AL520_RS05145	COG2814	Major facilitator Superfamily
AL520_RS05150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL520_RS05155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL520_RS05165	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL520_RS05210	COG0456	acetyltransferase
AL520_RS05255	COG2814	Major facilitator Superfamily
AL520_RS05260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL520_RS05280	COG1999	signal sequence binding
AL520_RS05290	COG1612	heme a metabolic process
AL520_RS05320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL520_RS05340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL520_RS05365	COG0070	glutamate synthase
AL520_RS05365	COG0069	glutamate synthase activity
AL520_RS05365	COG0067	glutamate synthase
AL520_RS05390	COG1984	allophanate hydrolase subunit 2
AL520_RS05405	COG0511	ligase activity, forming carbon-carbon bonds
AL520_RS05410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL520_RS05415	COG0583	DNA-binding transcription factor activity
AL520_RS05430	COG0477	Major facilitator Superfamily
AL520_RS05445	COG1127	ABC transporter
AL520_RS05450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL520_RS05455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL520_RS05460	COG2853	Lipoprotein
AL520_RS05470	COG1131	(ABC) transporter
AL520_RS05475	COG0842	Transport permease protein
AL520_RS05485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL520_RS05490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL520_RS05495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL520_RS05500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL520_RS05505	COG0131	Imidazoleglycerol-phosphate dehydratase
AL520_RS05510	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL520_RS05515	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL520_RS05520	COG0107	imidazoleglycerol-phosphate synthase activity
AL520_RS05525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL520_RS05530	COG0140	phosphoribosyl-ATP diphosphatase activity
AL520_RS05535	COG0537	adenosine 5'-monophosphoramidase activity
AL520_RS05540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL520_RS05545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL520_RS05565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL520_RS05570	COG1970	mechanosensitive ion channel activity
AL520_RS05575	COG0723	plastoquinol--plastocyanin reductase activity
AL520_RS05580	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL520_RS05585	COG2857	Cytochrome c1
AL520_RS05590	COG0625	glutathione transferase activity
AL520_RS05595	COG2969	positive regulation of protein catabolic process
AL520_RS05635	COG0583	DNA-binding transcription factor activity
AL520_RS05645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL520_RS05655	COG2207	Transcriptional regulator
AL520_RS05655	COG3708	Transcriptional regulator
AL520_RS05665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL520_RS05670	COG0747	negative chemotaxis
AL520_RS05675	COG0601	transmembrane transport
AL520_RS05680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS05690	COG1228	amidohydrolase
AL520_RS05695	COG5339	Protein conserved in bacteria
AL520_RS05700	COG5339	Protein conserved in bacteria
AL520_RS05705	COG0513	Belongs to the DEAD box helicase family
AL520_RS05710	COG1280	lysine exporter protein (LysE YggA)
AL520_RS05715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL520_RS05735	COG0583	DNA-binding transcription factor activity
AL520_RS05745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL520_RS05760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_RS05770	COG1609	Transcriptional regulator
AL520_RS05775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL520_RS05780	COG3842	ATPase activity
AL520_RS05785	COG1653	transport
AL520_RS05790	COG1175	transmembrane transport
AL520_RS05795	COG0395	ABC-type sugar transport system, permease component
AL520_RS05810	COG0018	arginyl-trna synthetase
AL520_RS05820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL520_RS05845	COG1280	lysine exporter protein (LysE YggA)
AL520_RS05860	COG1742	UPF0060 membrane protein
AL520_RS05870	COG1473	amidohydrolase
AL520_RS05875	COG1960	acyl-CoA dehydrogenase activity
AL520_RS05880	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AL520_RS05885	COG0183	Belongs to the thiolase family
AL520_RS05890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL520_RS05915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS05935	COG1280	lysine exporter protein (LysE YggA)
AL520_RS05945	COG3339	Conserved Protein
AL520_RS05955	COG3328	transposase activity
AL520_RS05985	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AL520_RS06005	COG4977	sequence-specific DNA binding
AL520_RS06015	COG0698	ribose 5-phosphate isomerase
AL520_RS06025	COG1595	DNA-templated transcription, initiation
AL520_RS06030	COG3712	iron ion homeostasis
AL520_RS06040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL520_RS06045	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS06050	COG1309	transcriptional regulator
AL520_RS06055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS06060	COG0765	amino acid transport
AL520_RS06065	COG0765	amino acid transport
AL520_RS06085	COG2358	TRAP transporter, solute receptor (TAXI family
AL520_RS06095	COG2922	Belongs to the Smg family
AL520_RS06100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL520_RS06110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL520_RS06110	COG0551	DNA topoisomerase type I activity
AL520_RS06125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS06130	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS06135	COG0028	Belongs to the TPP enzyme family
AL520_RS06140	COG1522	sequence-specific DNA binding
AL520_RS06145	COG3781	membrane
AL520_RS06160	COG2814	Major facilitator Superfamily
AL520_RS06175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL520_RS06190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL520_RS06200	COG1744	ABC transporter substrate-binding protein PnrA-like
AL520_RS06205	COG3845	ABC transporter
AL520_RS06210	COG4603	Belongs to the binding-protein-dependent transport system permease family
AL520_RS06220	COG0402	S-adenosylhomocysteine deaminase activity
AL520_RS06230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS06235	COG0583	DNA-binding transcription factor activity
AL520_RS06240	COG0251	oxidation-reduction process
AL520_RS06265	COG1177	transmembrane transport
AL520_RS06270	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_RS06275	COG3842	ATPase activity
AL520_RS06285	COG1609	Transcriptional regulator
AL520_RS06320	COG3328	transposase activity
AL520_RS06330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS06345	COG1177	transmembrane transport
AL520_RS06350	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_RS06355	COG3842	ATPase activity
AL520_RS06390	COG1126	abc transporter atp-binding protein
AL520_RS06395	COG0765	amino acid transport
AL520_RS06400	COG0765	amino acid transport
AL520_RS06405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS06410	COG0583	DNA-binding transcription factor activity
AL520_RS06420	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL520_RS06445	COG0583	DNA-binding transcription factor activity
AL520_RS06455	COG0592	DNA-directed DNA polymerase activity
AL520_RS06460	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL520_RS06465	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL520_RS06470	COG0594	ribonuclease P activity
AL520_RS06475	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL520_RS06485	COG0753	catalase activity
AL520_RS06500	COG2175	clavaminate synthase activity
AL520_RS06505	COG1473	amidohydrolase
AL520_RS06510	COG4608	Belongs to the ABC transporter superfamily
AL520_RS06515	COG0444	Belongs to the ABC transporter superfamily
AL520_RS06520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS06525	COG0601	transmembrane transport
AL520_RS06535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL520_RS06545	COG0038	chloride channel
AL520_RS06575	COG0436	Aminotransferase
AL520_RS06580	COG3180	Ammonia monooxygenase
AL520_RS06585	COG1278	Cold shock
AL520_RS06590	COG0445	tRNA wobble uridine modification
AL520_RS06595	COG0357	Ribosomal RNA small subunit methyltransferase G
AL520_RS06600	COG1192	Involved in chromosome partitioning
AL520_RS06610	COG1475	DNA binding
AL520_RS06615	COG0252	asparaginase activity
AL520_RS06620	COG0583	DNA-binding transcription factor activity
AL520_RS06645	COG1349	DNA-binding transcription factor activity
AL520_RS06655	COG3842	ATPase activity
AL520_RS06660	COG1840	ABC-type Fe3 transport system, periplasmic component
AL520_RS06675	COG1012	belongs to the aldehyde dehydrogenase family
AL520_RS06700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL520_RS06710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL520_RS06720	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL520_RS06725	COG0081	regulation of translation
AL520_RS06730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL520_RS06735	COG0222	ribosome binding
AL520_RS06740	COG0085	RNA polymerase activity
AL520_RS06745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL520_RS06760	COG5002	protein histidine kinase activity
AL520_RS06775	COG0745	RESPONSE REGULATOR receiver
AL520_RS06780	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL520_RS06785	COG0049	tRNA binding
AL520_RS06790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL520_RS06795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL520_RS06800	COG0051	transcription antitermination factor activity, RNA binding
AL520_RS06805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL520_RS06815	COG0089	rRNA binding
AL520_RS06820	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL520_RS06825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL520_RS06830	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL520_RS06835	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL520_RS06840	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL520_RS06845	COG0255	Belongs to the universal ribosomal protein uL29 family
AL520_RS06850	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL520_RS06865	COG4177	L-phenylalanine transmembrane transporter activity
AL520_RS06885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_RS06890	COG2207	Transcriptional regulator
AL520_RS06915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL520_RS06920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL520_RS06925	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL520_RS06930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL520_RS06935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL520_RS06940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL520_RS06945	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL520_RS06950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL520_RS06955	COG1841	ribosomal large subunit assembly
AL520_RS06960	COG0200	Binds to the 23S rRNA
AL520_RS06965	COG0201	protein transport
AL520_RS06970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL520_RS06975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL520_RS06980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL520_RS06985	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL520_RS06990	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL520_RS06995	COG0202	RNA polymerase activity
AL520_RS07000	COG0203	ribosomal protein L17
AL520_RS07010	COG1324	tolerance protein
AL520_RS07015	COG4232	protein-disulfide reductase activity
AL520_RS07030	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL520_RS07040	COG1333	cytochrome c biogenesis protein
AL520_RS07045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL520_RS07050	COG0019	diaminopimelate decarboxylase activity
AL520_RS07060	COG1965	Belongs to the frataxin family
AL520_RS07070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL520_RS07075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL520_RS07080	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL520_RS07085	COG0625	glutathione transferase activity
AL520_RS07095	COG2814	Major facilitator Superfamily
AL520_RS07105	COG2226	methyltransferase
AL520_RS07140	COG2186	Transcriptional regulator
AL520_RS07155	COG1422	Protein of unknown function (DUF1090)
AL520_RS07165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS07170	COG1956	GAF domain-containing protein
AL520_RS07175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_RS07190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL520_RS07215	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL520_RS07220	COG3568	Endonuclease Exonuclease Phosphatase
AL520_RS07250	COG2814	Major facilitator Superfamily
AL520_RS07260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL520_RS07285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL520_RS07310	COG0859	PFAM glycosyl transferase family 9
AL520_RS07320	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AL520_RS07330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL520_RS07355	COG1686	Belongs to the peptidase S11 family
AL520_RS07365	COG2921	Belongs to the UPF0250 family
AL520_RS07370	COG0321	lipoyl(octanoyl) transferase activity
AL520_RS07380	COG1609	Transcriptional regulator
AL520_RS07385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL520_RS07390	COG2096	Adenosyltransferase
AL520_RS07400	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL520_RS07405	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL520_RS07415	COG0523	cobalamin synthesis protein
AL520_RS07420	COG0735	belongs to the Fur family
AL520_RS07440	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL520_RS07450	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL520_RS07455	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL520_RS07465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL520_RS07470	COG1560	Kdo2-lipid A biosynthetic process
AL520_RS07480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL520_RS07485	COG0154	amidase activity
AL520_RS07505	COG1079	Belongs to the binding-protein-dependent transport system permease family
AL520_RS07525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL520_RS07530	COG0583	DNA-binding transcription factor activity
AL520_RS07535	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS07545	COG0066	3-isopropylmalate dehydratase activity
AL520_RS07560	COG0438	transferase activity, transferring glycosyl groups
AL520_RS07565	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL520_RS07570	COG1950	PFAM Membrane protein of
AL520_RS07590	COG1305	Transglutaminase-like
AL520_RS07600	COG2308	Evidence 4 Homologs of previously reported genes of
AL520_RS07605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL520_RS07615	COG0617	tRNA 3'-terminal CCA addition
AL520_RS07625	COG0513	Belongs to the DEAD box helicase family
AL520_RS07630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL520_RS07665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL520_RS07665	COG0352	thiamine-phosphate diphosphorylase activity
AL520_RS07665	COG0351	phosphomethylpyrimidine kinase
AL520_RS07670	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS07690	COG3189	MarR family transcriptional regulator
AL520_RS07700	COG0297	glycogen (starch) synthase activity
AL520_RS07725	COG0640	Transcriptional regulator
AL520_RS07785	COG1846	Transcriptional regulator
AL520_RS07790	COG1764	response to oxidative stress
AL520_RS07815	COG0583	DNA-binding transcription factor activity
AL520_RS07830	COG0583	DNA-binding transcription factor activity
AL520_RS07845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL520_RS07850	COG0708	Exodeoxyribonuclease III
AL520_RS07855	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL520_RS07870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL520_RS07875	COG0154	amidase activity
AL520_RS07880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL520_RS07885	COG1077	Cell shape determining protein MreB Mrl
AL520_RS07890	COG1792	Involved in formation and maintenance of cell shape
AL520_RS07900	COG0768	penicillin binding
AL520_RS07905	COG0772	Belongs to the SEDS family
AL520_RS07910	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL520_RS07915	COG0471	metal ion transport
AL520_RS07920	COG1309	transcriptional regulator
AL520_RS07930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL520_RS07940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_RS07950	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL520_RS07965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL520_RS07975	COG1660	Displays ATPase and GTPase activities
AL520_RS07990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS07995	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AL520_RS08005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL520_RS08010	COG1137	ATPase activity
AL520_RS08025	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL520_RS08035	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL520_RS08050	COG1294	oxidase, subunit
AL520_RS08060	COG4988	ABC transporter
AL520_RS08065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL520_RS08070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL520_RS08085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS08090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL520_RS08095	COG1238	metal cluster binding
AL520_RS08110	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS08115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL520_RS08120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS08125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS08140	COG0758	DNA mediated transformation
AL520_RS08145	COG0242	peptide deformylase activity
AL520_RS08150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL520_RS08160	COG0546	phosphoglycolate phosphatase activity
AL520_RS08180	COG1733	regulation of RNA biosynthetic process
AL520_RS08190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL520_RS08195	COG1280	lysine exporter protein (LysE YggA)
AL520_RS08200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL520_RS08200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL520_RS08210	COG5000	phosphorelay sensor kinase activity
AL520_RS08215	COG2204	response regulator
AL520_RS08220	COG0569	domain protein
AL520_RS08225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL520_RS08230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AL520_RS08235	COG2226	methyltransferase
AL520_RS08240	COG1040	competence protein
AL520_RS08255	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL520_RS08260	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL520_RS08265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL520_RS08270	COG1054	Belongs to the UPF0176 family
AL520_RS08275	COG0588	phosphoglycerate mutase activity
AL520_RS08280	COG4942	peptidase
AL520_RS08285	COG0793	Belongs to the peptidase S41A family
AL520_RS08290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL520_RS08295	COG5002	protein histidine kinase activity
AL520_RS08295	COG5001	Diguanylate cyclase
AL520_RS08295	COG3447	MASE1 domain protein
AL520_RS08300	COG2186	Transcriptional regulator
AL520_RS08310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL520_RS08315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL520_RS08315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL520_RS08330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL520_RS08335	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL520_RS08340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL520_RS08345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL520_RS08350	COG0142	geranyltranstransferase activity
AL520_RS08405	COG0235	Class ii aldolase
AL520_RS08410	COG3622	Belongs to the hyi family
AL520_RS08415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_RS08420	COG2084	Dehydrogenase
AL520_RS08425	COG3395	kinase activity
AL520_RS08430	COG2186	Transcriptional regulator
AL520_RS08455	COG3622	Belongs to the hyi family
AL520_RS08475	COG1522	sequence-specific DNA binding
AL520_RS08480	COG1280	lysine exporter protein (LysE YggA)
AL520_RS08495	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL520_RS08500	COG2890	protein-(glutamine-N5) methyltransferase activity
AL520_RS08505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL520_RS08520	COG1464	Belongs to the NlpA lipoprotein family
AL520_RS08540	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS08565	COG0477	Major facilitator Superfamily
AL520_RS08570	COG0583	DNA-binding transcription factor activity
AL520_RS08580	COG0583	DNA-binding transcription factor activity
AL520_RS08595	COG0625	glutathione transferase activity
AL520_RS08600	COG1053	succinate dehydrogenase
AL520_RS08610	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS08630	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_RS08640	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS08645	COG1802	Transcriptional regulator
AL520_RS08650	COG0288	reversible hydration of carbon dioxide
AL520_RS08670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_RS08680	COG4829	muconolactone delta-isomerase
AL520_RS08685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL520_RS08695	COG1414	Transcriptional regulator
AL520_RS08700	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS08705	COG2031	fatty acid transporter
AL520_RS08710	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_RS08715	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL520_RS08720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL520_RS08725	COG3300	MHYT domain
AL520_RS08725	COG5001	Diguanylate cyclase
AL520_RS08740	COG0583	DNA-binding transcription factor activity
AL520_RS08745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_RS08755	COG0129	dihydroxy-acid dehydratase activity
AL520_RS08760	COG0583	DNA-binding transcription factor activity
AL520_RS08765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL520_RS08780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL520_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS08790	COG0410	ABC transporter
AL520_RS08815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL520_RS08825	COG2186	Transcriptional regulator
AL520_RS08835	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AL520_RS08855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_RS08860	COG0583	DNA-binding transcription factor activity
AL520_RS08865	COG0628	permease
AL520_RS08885	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_RS08890	COG3842	ATPase activity
AL520_RS08900	COG0277	FAD linked oxidase domain protein
AL520_RS08915	COG0477	Major facilitator Superfamily
AL520_RS08935	COG1695	Transcriptional regulator
AL520_RS08945	COG0583	DNA-binding transcription factor activity
AL520_RS08970	COG0745	RESPONSE REGULATOR receiver
AL520_RS08975	COG2198	Histidine kinase
AL520_RS08975	COG0784	Response regulator, receiver
AL520_RS08975	COG5002	protein histidine kinase activity
AL520_RS09080	COG0583	DNA-binding transcription factor activity
AL520_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS09095	COG3246	L-lysine catabolic process to acetate
AL520_RS09100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL520_RS09105	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL520_RS09120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_RS09130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS09140	COG2755	lipolytic protein G-D-S-L family
AL520_RS09140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL520_RS09185	COG0582	viral genome integration into host DNA
AL520_RS09225	COG0629	single-stranded DNA binding
AL520_RS09365	COG3566	protein conserved in bacteria
AL520_RS09530	COG3621	Patatin-like phospholipase
AL520_RS09570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL520_RS09575	COG0501	Belongs to the peptidase M48B family
AL520_RS09605	COG0542	response to heat
AL520_RS09630	COG0071	Belongs to the small heat shock protein (HSP20) family
AL520_RS09660	COG0556	nucleotide-excision repair
AL520_RS09685	COG2233	PERMEase
AL520_RS09695	COG0326	Molecular chaperone. Has ATPase activity
AL520_RS09700	COG1396	sequence-specific DNA binding
AL520_RS09705	COG3550	peptidyl-serine autophosphorylation
AL520_RS09715	COG4774	siderophore transport
AL520_RS09730	COG1131	(ABC) transporter
AL520_RS09735	COG2271	Major facilitator Superfamily
AL520_RS09740	COG4948	Mandelate Racemase Muconate Lactonizing
AL520_RS09745	COG0800	Aldolase
AL520_RS09755	COG1414	Transcriptional regulator
AL520_RS09805	COG1012	belongs to the aldehyde dehydrogenase family
AL520_RS09830	COG0625	glutathione transferase activity
AL520_RS09845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL520_RS09850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL520_RS09855	COG1652	LysM domain
AL520_RS09870	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL520_RS09875	COG0583	DNA-binding transcription factor activity
AL520_RS09880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS09885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_RS09900	COG0582	viral genome integration into host DNA
AL520_RS09975	COG2003	Belongs to the UPF0758 family
AL520_RS10035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL520_RS10040	COG0464	growth
AL520_RS10055	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AL520_RS10155	COG0443	Heat shock 70 kDa protein
AL520_RS10175	COG3344	reverse transcriptase
AL520_RS10245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL520_RS10310	COG0583	DNA-binding transcription factor activity
AL520_RS10315	COG0583	DNA-binding transcription factor activity
AL520_RS10335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL520_RS10355	COG3246	L-lysine catabolic process to acetate
AL520_RS10360	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS10365	COG2205	protein histidine kinase activity
AL520_RS10370	COG0165	Argininosuccinate lyase
AL520_RS10380	COG2828	Protein conserved in bacteria
AL520_RS10395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL520_RS10435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL520_RS10455	COG0625	glutathione transferase activity
AL520_RS10465	COG3258	Cytochrome c
AL520_RS10500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS10510	COG1294	oxidase, subunit
AL520_RS10515	COG1271	oxidase subunit
AL520_RS10520	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS10530	COG0842	Transport permease protein
AL520_RS10540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_RS10550	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL520_RS10560	COG2200	EAL domain
AL520_RS10585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL520_RS10590	COG0745	RESPONSE REGULATOR receiver
AL520_RS10615	COG1054	Belongs to the UPF0176 family
AL520_RS10620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL520_RS10620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL520_RS10630	COG0489	protein tyrosine kinase activity
AL520_RS10645	COG0717	Belongs to the dCTP deaminase family
AL520_RS10655	COG3706	GGDEF domain
AL520_RS10675	COG2081	HI0933 family
AL520_RS10690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL520_RS10695	COG0509	glycine decarboxylation via glycine cleavage system
AL520_RS10700	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL520_RS10700	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL520_RS10715	COG0154	amidase activity
AL520_RS10720	COG4172	Belongs to the ABC transporter superfamily
AL520_RS10725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS10730	COG0601	transmembrane transport
AL520_RS10735	COG0747	negative chemotaxis
AL520_RS10750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL520_RS10755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS10780	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AL520_RS10785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL520_RS10790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL520_RS10805	COG0438	transferase activity, transferring glycosyl groups
AL520_RS10815	COG0438	transferase activity, transferring glycosyl groups
AL520_RS10820	COG0438	transferase activity, transferring glycosyl groups
AL520_RS10830	COG0405	Gamma-glutamyltransferase
AL520_RS10835	COG0166	Belongs to the GPI family
AL520_RS10850	COG0277	FAD linked oxidase domain protein
AL520_RS10855	COG0745	RESPONSE REGULATOR receiver
AL520_RS10860	COG2205	protein histidine kinase activity
AL520_RS10870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_RS10870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL520_RS10880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_RS10890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_RS10895	COG2186	Transcriptional regulator
AL520_RS10900	COG1368	sulfuric ester hydrolase activity
AL520_RS10905	COG0204	Acyl-transferase
AL520_RS10915	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL520_RS10940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL520_RS10955	COG0840	transmembrane signaling receptor activity
AL520_RS10960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL520_RS10980	COG0193	aminoacyl-tRNA hydrolase activity
AL520_RS10990	COG0012	GTP binding
AL520_RS10995	COG0582	viral genome integration into host DNA
AL520_RS11015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL520_RS11050	COG0488	(ABC) transporter
AL520_RS11060	COG2814	Major facilitator Superfamily
AL520_RS11075	COG3135	benzoate transporter
AL520_RS11080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL520_RS11085	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL520_RS11090	COG0742	ribosomal rna small subunit methyltransferase
AL520_RS11105	COG3639	organic phosphonate transmembrane transporter activity
AL520_RS11110	COG3639	organic phosphonate transmembrane transporter activity
AL520_RS11115	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL520_RS11140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL520_RS11145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL520_RS11150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL520_RS11155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL520_RS11160	COG1546	Belongs to the CinA family
AL520_RS11165	COG0284	orotidine-5'-phosphate decarboxylase activity
AL520_RS11170	COG1252	NADH dehydrogenase
AL520_RS11175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL520_RS11180	COG0246	Mannitol dehydrogenase
AL520_RS11190	COG1137	ATPase activity
AL520_RS11215	COG1917	Cupin 2, conserved barrel domain protein
AL520_RS11235	COG1846	Transcriptional regulator
AL520_RS11245	COG0459	protein refolding
AL520_RS11250	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL520_RS11295	COG1686	Belongs to the peptidase S11 family
AL520_RS11315	COG4191	Histidine kinase
AL520_RS11340	COG2200	EAL domain
AL520_RS11385	COG0793	Belongs to the peptidase S41A family
AL520_RS11410	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL520_RS11420	COG0745	RESPONSE REGULATOR receiver
AL520_RS11460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL520_RS11495	COG0697	spore germination
AL520_RS11515	COG0431	NADPH-dependent FMN reductase
AL520_RS11520	COG1393	Belongs to the ArsC family
AL520_RS11525	COG0798	PFAM Bile acid sodium symporter
AL520_RS11540	COG1793	dna ligase
AL520_RS11545	COG1201	RNA secondary structure unwinding
AL520_RS11555	COG1132	(ABC) transporter
AL520_RS11555	COG2375	cellular response to nickel ion
AL520_RS11575	COG1230	cation diffusion facilitator family transporter
AL520_RS11600	COG0028	Belongs to the TPP enzyme family
AL520_RS11645	COG0596	Alpha beta hydrolase
AL520_RS11655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_RS11680	COG0740	serine-type endopeptidase activity
AL520_RS11690	COG0640	Transcriptional regulator
AL520_RS11695	COG2199	diguanylate cyclase activity
AL520_RS11695	COG2203	Gaf domain
AL520_RS11700	COG0840	transmembrane signaling receptor activity
AL520_RS11725	COG0454	-acetyltransferase
AL520_RS11725	COG0456	acetyltransferase
AL520_RS11735	COG0023	Translation Initiation Factor
AL520_RS11740	COG0583	DNA-binding transcription factor activity
AL520_RS11745	COG0656	L-ascorbic acid biosynthetic process
AL520_RS11750	COG0667	Aldo Keto reductase
AL520_RS11760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL520_RS11760	COG2146	nitrite reductase [NAD(P)H] activity
AL520_RS11765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL520_RS11765	COG2146	nitrite reductase [NAD(P)H] activity
AL520_RS11770	COG3707	response regulator
AL520_RS11790	COG2197	response regulator
AL520_RS11825	COG2814	Major facilitator Superfamily
AL520_RS11835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS11840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS11850	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL520_RS11855	COG1845	cytochrome c oxidase, subunit III
AL520_RS11860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL520_RS11865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL520_RS11870	COG0477	Major facilitator Superfamily
AL520_RS11910	COG0583	DNA-binding transcription factor activity
AL520_RS11925	COG4106	trans-aconitate 2-methyltransferase activity
AL520_RS11930	COG2207	Transcriptional regulator
AL520_RS11935	COG2807	transmembrane transport
AL520_RS11960	COG0330	HflC and HflK could
AL520_RS11965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL520_RS11980	COG3712	iron ion homeostasis
AL520_RS11995	COG3712	iron ion homeostasis
AL520_RS12010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL520_RS12020	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL520_RS12025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL520_RS12030	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS12035	COG1285	pathogenesis
AL520_RS12040	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL520_RS12055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL520_RS12060	COG3145	DNA-N1-methyladenine dioxygenase activity
AL520_RS12070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL520_RS12075	COG1396	sequence-specific DNA binding
AL520_RS12080	COG0456	acetyltransferase
AL520_RS12095	COG0583	DNA-binding transcription factor activity
AL520_RS12105	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS12140	COG0697	spore germination
AL520_RS12155	COG0280	phosphate acetyltransferase
AL520_RS12155	COG0281	malic enzyme
AL520_RS12195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL520_RS12200	COG1845	cytochrome c oxidase, subunit III
AL520_RS12205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL520_RS12215	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AL520_RS12235	COG1999	signal sequence binding
AL520_RS12260	COG1126	abc transporter atp-binding protein
AL520_RS12265	COG0765	amino acid transport
AL520_RS12270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS12275	COG3191	aminopeptidase activity
AL520_RS12280	COG1272	protein, Hemolysin III
AL520_RS12285	COG1522	sequence-specific DNA binding
AL520_RS12295	COG1113	amino acid transport
AL520_RS12325	COG2378	regulation of single-species biofilm formation
AL520_RS12355	COG1595	DNA-templated transcription, initiation
AL520_RS12360	COG3712	iron ion homeostasis
AL520_RS12370	COG3720	iron ion transport
AL520_RS12375	COG4558	Periplasmic binding protein
AL520_RS12380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_RS12385	COG1120	ATPase activity
AL520_RS12390	COG1666	GTP binding
AL520_RS12410	COG0671	phosphoesterase, PA-phosphatase related
AL520_RS12425	COG4774	siderophore transport
AL520_RS12450	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_RS12490	COG0456	acetyltransferase
AL520_RS12495	COG0583	DNA-binding transcription factor activity
AL520_RS12500	COG2828	Protein conserved in bacteria
AL520_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS12570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL520_RS12575	COG0583	DNA-binding transcription factor activity
AL520_RS12600	COG2223	nitrite transmembrane transporter activity
AL520_RS12610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL520_RS12615	COG3383	formate dehydrogenase (NAD+) activity
AL520_RS12635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL520_RS12645	COG0303	'Molybdopterin
AL520_RS12650	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL520_RS12655	COG0314	molybdopterin synthase activity
AL520_RS12665	COG0315	cyclic pyranopterin monophosphate synthase activity
AL520_RS12675	COG0412	Dienelactone hydrolase
AL520_RS12685	COG0678	peroxiredoxin activity
AL520_RS12695	COG0697	spore germination
AL520_RS12740	COG0667	Aldo Keto reductase
AL520_RS12745	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL520_RS12750	COG4535	Mg2 and Co2 transporter CorC
AL520_RS12755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL520_RS12760	COG1702	phosphate starvation-inducible protein PhoH
AL520_RS12765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL520_RS12775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL520_RS12785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL520_RS12790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL520_RS12795	COG1862	Preprotein translocase
AL520_RS12800	COG3077	Addiction module antitoxin, RelB DinJ family
AL520_RS12810	COG0343	queuine tRNA-ribosyltransferase activity
AL520_RS12815	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL520_RS12825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL520_RS12840	COG2027	D-alanyl-D-alanine carboxypeptidase
AL520_RS12845	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL520_RS12850	COG1648	precorrin-2 dehydrogenase activity
AL520_RS12850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL520_RS12855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_RS12860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS12865	COG1116	anion transmembrane transporter activity
AL520_RS12875	COG4575	ribosome binding
AL520_RS12890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL520_RS12895	COG0741	lytic transglycosylase activity
AL520_RS12905	COG0436	Aminotransferase
AL520_RS12915	COG0280	phosphate acetyltransferase
AL520_RS12915	COG0281	malic enzyme
AL520_RS12925	COG2732	(Barnase) inhibitor
AL520_RS12930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL520_RS12940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL520_RS12945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL520_RS12950	COG0126	phosphoglycerate kinase activity
AL520_RS12965	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL520_RS12970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL520_RS12990	COG0625	glutathione transferase activity
AL520_RS13025	COG0306	phosphate transporter
AL520_RS13035	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL520_RS13045	COG0739	heme binding
AL520_RS13055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL520_RS13065	COG0640	Transcriptional regulator
AL520_RS13075	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL520_RS13080	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL520_RS13085	COG3639	organic phosphonate transmembrane transporter activity
AL520_RS13105	COG0583	DNA-binding transcription factor activity
AL520_RS13110	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL520_RS13120	COG3454	Phosphonate metabolism
AL520_RS13125	COG2188	Transcriptional regulator
AL520_RS13130	COG3624	Phosphonate C-P lyase system protein PhnG
AL520_RS13135	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL520_RS13140	COG3626	phosphonate metabolism
AL520_RS13145	COG3627	carbon phosphorus lyase activity
AL520_RS13150	COG4107	phosphonate C-P lyase system protein PhnK
AL520_RS13155	COG4778	phosphonate C-P lyase system protein PhnL
AL520_RS13160	COG3454	Phosphonate metabolism
AL520_RS13180	COG1301	dicarboxylic acid transport
AL520_RS13200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL520_RS13205	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL520_RS13210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL520_RS13215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL520_RS13220	COG0009	L-threonylcarbamoyladenylate synthase
AL520_RS13225	COG1414	Transcriptional regulator
AL520_RS13230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL520_RS13245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS13250	COG1414	Transcriptional regulator
AL520_RS13255	COG0010	Belongs to the arginase family
AL520_RS13265	COG0765	amino acid transport
AL520_RS13270	COG1126	abc transporter atp-binding protein
AL520_RS13275	COG0028	Belongs to the TPP enzyme family
AL520_RS13320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL520_RS13340	COG2030	dehydratase
AL520_RS13370	COG0028	Belongs to the TPP enzyme family
AL520_RS13375	COG0583	DNA-binding transcription factor activity
AL520_RS13380	COG4974	Belongs to the 'phage' integrase family
AL520_RS13385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL520_RS13405	COG1686	Belongs to the peptidase S11 family
AL520_RS13595	COG4695	Portal protein
AL520_RS13610	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS13615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_RS13625	COG1024	Enoyl-CoA hydratase
AL520_RS13630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS13650	COG2070	2-Nitropropane dioxygenase
AL520_RS13665	COG1074	ATP-dependent DNA helicase activity
AL520_RS13670	COG2801	Transposase and inactivated derivatives
AL520_RS13670	COG3415	Transposase
AL520_RS13695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS13700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_RS13710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS13725	COG0745	RESPONSE REGULATOR receiver
AL520_RS13745	COG0505	Belongs to the CarA family
AL520_RS13750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL520_RS13760	COG4221	oxidoreductase activity
AL520_RS13765	COG0406	alpha-ribazole phosphatase activity
AL520_RS13775	COG3842	ATPase activity
AL520_RS13795	COG2233	PERMEase
AL520_RS13800	COG0840	transmembrane signaling receptor activity
AL520_RS13805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL520_RS13810	COG1534	Rna-binding protein
AL520_RS13815	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL520_RS13820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL520_RS13830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL520_RS13865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL520_RS13870	COG2814	Major facilitator Superfamily
AL520_RS13880	COG0477	Major facilitator Superfamily
AL520_RS13885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL520_RS13900	COG2841	Protein conserved in bacteria
AL520_RS13915	COG1595	DNA-templated transcription, initiation
AL520_RS13925	COG2207	Transcriptional regulator
AL520_RS13930	COG0667	Aldo Keto reductase
AL520_RS13950	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL520_RS13955	COG0500	methyltransferase
AL520_RS13985	COG0517	IMP dehydrogenase activity
AL520_RS13995	COG3938	Belongs to the proline racemase family
AL520_RS14000	COG1177	transmembrane transport
AL520_RS14005	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_RS14010	COG3842	ATPase activity
AL520_RS14070	COG3264	Mechanosensitive ion channel
AL520_RS14070	COG1511	domain protein
AL520_RS14075	COG0583	DNA-binding transcription factor activity
AL520_RS14080	COG0427	acetyl-CoA hydrolase
AL520_RS14085	COG0583	DNA-binding transcription factor activity
AL520_RS14120	COG2204	response regulator
AL520_RS14125	COG4191	Histidine kinase
AL520_RS14130	COG1301	dicarboxylic acid transport
AL520_RS14140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL520_RS14145	COG0799	negative regulation of ribosome biogenesis
AL520_RS14150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL520_RS14160	COG0151	Belongs to the GarS family
AL520_RS14165	COG0217	transcriptional regulatory protein
AL520_RS14170	COG0433	COG0433 Predicted ATPase
AL520_RS14175	COG0473	3-isopropylmalate dehydrogenase activity
AL520_RS14185	COG2814	Major facilitator Superfamily
AL520_RS14190	COG1566	PFAM secretion protein HlyD family protein
AL520_RS14200	COG1846	Transcriptional regulator
AL520_RS14230	COG3391	amine dehydrogenase activity
AL520_RS14240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL520_RS14260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL520_RS14265	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL520_RS14280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL520_RS14305	COG1309	transcriptional regulator
AL520_RS14310	COG2311	Membrane
AL520_RS14315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL520_RS14340	COG0662	Cupin 2, conserved barrel domain protein
AL520_RS14345	COG5285	phytanoyl-CoA dioxygenase
AL520_RS14350	COG0633	Ferredoxin
AL520_RS14350	COG3217	Mosc domain protein beta barrel domain protein
AL520_RS14355	COG2076	Multidrug Resistance protein
AL520_RS14360	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL520_RS14370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS14385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL520_RS14390	COG0425	Belongs to the sulfur carrier protein TusA family
AL520_RS14400	COG0228	four-way junction DNA binding
AL520_RS14410	COG0336	Belongs to the RNA methyltransferase TrmD family
AL520_RS14420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS14425	COG0765	amino acid transport
AL520_RS14430	COG1126	abc transporter atp-binding protein
AL520_RS14435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS14440	COG0525	valine-tRNA ligase activity
AL520_RS14445	COG0105	UTP biosynthetic process
AL520_RS14450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL520_RS14470	COG2976	Protein conserved in bacteria
AL520_RS14475	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL520_RS14480	COG1160	GTP binding
AL520_RS14485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL520_RS14490	COG1923	regulation of RNA biosynthetic process
AL520_RS14495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL520_RS14500	COG0330	HflC and HflK could
AL520_RS14505	COG0330	HflC and HflK could
AL520_RS14510	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AL520_RS14515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL520_RS14520	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL520_RS14525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL520_RS14545	COG0582	viral genome integration into host DNA
AL520_RS14580	COG0419	ATPase involved in DNA repair
AL520_RS14635	COG1396	sequence-specific DNA binding
AL520_RS14705	COG5410	chromosome segregation
AL520_RS14880	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AL520_RS14890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL520_RS14900	COG2391	methyltransferase activity
AL520_RS14905	COG0679	Auxin Efflux Carrier
AL520_RS14935	COG0557	exoribonuclease II activity
AL520_RS14940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL520_RS14945	COG2873	o-acetylhomoserine
AL520_RS14950	COG3128	pkhd-type hydroxylase
AL520_RS14955	COG0776	regulation of translation
AL520_RS14985	COG0642	Histidine kinase
AL520_RS14990	COG3158	transport of potassium into the cell
AL520_RS15000	COG0137	argininosuccinate synthase activity
AL520_RS15005	COG1538	Outer membrane efflux protein
AL520_RS15010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_RS15020	COG5002	protein histidine kinase activity
AL520_RS15025	COG0583	DNA-binding transcription factor activity
AL520_RS15030	COG3618	amidohydrolase
AL520_RS15050	COG2945	thiolester hydrolase activity
AL520_RS15050	COG0596	Alpha beta hydrolase
AL520_RS15055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL520_RS15060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL520_RS15080	COG0747	negative chemotaxis
AL520_RS15085	COG0601	transmembrane transport
AL520_RS15090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS15110	COG4608	Belongs to the ABC transporter superfamily
AL520_RS15120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL520_RS15120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_RS15130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_RS15135	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL520_RS15145	COG3642	lipopolysaccharide core region biosynthetic process
AL520_RS15155	COG3842	ATPase activity
AL520_RS15160	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_RS15165	COG1177	transmembrane transport
AL520_RS15195	COG1960	acyl-CoA dehydrogenase activity
AL520_RS15205	COG0704	Plays a role in the regulation of phosphate uptake
AL520_RS15215	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL520_RS15220	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL520_RS15220	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL520_RS15225	COG1643	Atp-dependent helicase
AL520_RS15230	COG0395	ABC-type sugar transport system, permease component
AL520_RS15235	COG1116	anion transmembrane transporter activity
AL520_RS15250	COG0438	transferase activity, transferring glycosyl groups
AL520_RS15255	COG0726	polysaccharide deacetylase
AL520_RS15270	COG0726	polysaccharide deacetylase
AL520_RS15295	COG1132	(ABC) transporter
AL520_RS15300	COG0475	glutathione-regulated potassium exporter activity
AL520_RS15300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL520_RS15315	COG4251	negative regulation of phosphorylation
AL520_RS15315	COG3706	GGDEF domain
AL520_RS15315	COG5001	Diguanylate cyclase
AL520_RS15315	COG2203	Gaf domain
AL520_RS15325	COG1530	ribonuclease E activity
AL520_RS15365	COG0583	DNA-binding transcription factor activity
AL520_RS15380	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_RS15390	COG0477	Major facilitator Superfamily
AL520_RS15400	COG0154	amidase activity
AL520_RS15420	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL520_RS15435	COG0495	leucyl-tRNA aminoacylation
AL520_RS15440	COG2814	Major facilitator Superfamily
AL520_RS15445	COG1846	Transcriptional regulator
AL520_RS15455	COG1686	Belongs to the peptidase S11 family
AL520_RS15490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL520_RS15495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL520_RS15500	COG2814	Major facilitator Superfamily
AL520_RS15505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL520_RS15515	COG4176	ABC-type proline glycine betaine transport system permease component
AL520_RS15535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_RS15540	COG2706	6-phosphogluconolactonase activity
AL520_RS15545	COG4214	carbohydrate transport
AL520_RS15550	COG1129	ABC transporter
AL520_RS15555	COG4213	ABC transporter substrate-binding protein
AL520_RS15580	COG0583	DNA-binding transcription factor activity
AL520_RS15585	COG1960	acyl-CoA dehydrogenase activity
AL520_RS15590	COG1960	acyl-CoA dehydrogenase activity
AL520_RS15595	COG0183	Belongs to the thiolase family
AL520_RS15605	COG1802	Transcriptional regulator
AL520_RS15615	COG1024	Enoyl-CoA hydratase
AL520_RS15620	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS15630	COG0667	Aldo Keto reductase
AL520_RS15640	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL520_RS15655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS15665	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL520_RS15685	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AL520_RS15690	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL520_RS15695	COG4149	molybdate abc transporter
AL520_RS15700	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL520_RS15725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_RS15730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_RS15740	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL520_RS15745	COG0736	holo-[acyl-carrier-protein] synthase activity
AL520_RS15760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL520_RS15770	COG0473	3-isopropylmalate dehydrogenase activity
AL520_RS15775	COG0583	DNA-binding transcription factor activity
AL520_RS15780	COG1858	cytochrome C peroxidase
AL520_RS15785	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL520_RS15785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL520_RS15790	COG2224	Isocitrate lyase
AL520_RS15795	COG0583	DNA-binding transcription factor activity
AL520_RS15810	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL520_RS15835	COG0156	8-amino-7-oxononanoate synthase activity
AL520_RS15840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL520_RS15855	COG3278	Belongs to the heme-copper respiratory oxidase family
AL520_RS15875	COG0348	domain, Protein
AL520_RS15920	COG1012	belongs to the aldehyde dehydrogenase family
AL520_RS15930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS15940	COG0765	amino acid transport
AL520_RS15945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS15950	COG1396	sequence-specific DNA binding
AL520_RS15975	COG3546	catalase activity
AL520_RS15995	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL520_RS16000	COG0438	transferase activity, transferring glycosyl groups
AL520_RS16020	COG1566	PFAM secretion protein HlyD family protein
AL520_RS16035	COG0583	DNA-binding transcription factor activity
AL520_RS16040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS16045	COG0586	Pfam SNARE associated Golgi protein
AL520_RS16050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS16065	COG4608	Belongs to the ABC transporter superfamily
AL520_RS16070	COG0444	Belongs to the ABC transporter superfamily
AL520_RS16075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS16080	COG0601	transmembrane transport
AL520_RS16085	COG0583	DNA-binding transcription factor activity
AL520_RS16090	COG1764	response to oxidative stress
AL520_RS16095	COG2205	protein histidine kinase activity
AL520_RS16135	COG1802	Transcriptional regulator
AL520_RS16155	COG2084	Dehydrogenase
AL520_RS16165	COG1917	Cupin 2, conserved barrel domain protein
AL520_RS16165	COG2207	Transcriptional regulator
AL520_RS16205	COG1280	lysine exporter protein (LysE YggA)
AL520_RS16210	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS16220	COG0840	transmembrane signaling receptor activity
AL520_RS16255	COG3121	Chaperone
AL520_RS16260	COG3188	usher protein
AL520_RS16280	COG0642	Histidine kinase
AL520_RS16285	COG1475	DNA binding
AL520_RS16295	COG3969	phosphoadenosine phosphosulfate
AL520_RS16300	COG1971	Probably functions as a manganese efflux pump
AL520_RS16305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL520_RS16360	COG2321	neutral zinc metallopeptidase
AL520_RS16365	COG0009	L-threonylcarbamoyladenylate synthase
AL520_RS16370	COG1994	Peptidase M50
AL520_RS16375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_RS16380	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL520_RS16390	COG2850	peptidyl-arginine hydroxylation
AL520_RS16395	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL520_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS16460	COG0583	DNA-binding transcription factor activity
AL520_RS16470	COG3360	Dodecin
AL520_RS16510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS16515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_RS16555	COG0668	transmembrane transport
AL520_RS16580	COG0483	inositol monophosphate 1-phosphatase activity
AL520_RS16585	COG1253	flavin adenine dinucleotide binding
AL520_RS16590	COG1968	undecaprenyl-diphosphatase activity
AL520_RS16595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL520_RS16600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL520_RS16610	COG0215	cysteine-tRNA ligase activity
AL520_RS16620	COG0825	malonyl-CoA metabolic process
AL520_RS16625	COG0037	tRNA processing
AL520_RS16630	COG0527	aspartate kinase activity
AL520_RS16645	COG0348	domain, Protein
AL520_RS16665	COG3278	Belongs to the heme-copper respiratory oxidase family
AL520_RS16675	COG2217	Heavy metal translocating P-type atpase
AL520_RS16680	COG3258	Cytochrome c
AL520_RS16685	COG2863	cytochrome
AL520_RS16700	COG0784	Response regulator, receiver
AL520_RS16700	COG2205	protein histidine kinase activity
AL520_RS16710	COG2205	protein histidine kinase activity
AL520_RS16710	COG0784	Response regulator, receiver
AL520_RS16725	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AL520_RS16735	COG1309	transcriptional regulator
AL520_RS16765	COG0456	acetyltransferase
AL520_RS16775	COG0583	DNA-binding transcription factor activity
AL520_RS16795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL520_RS16805	COG1414	Transcriptional regulator
AL520_RS16815	COG1024	Enoyl-CoA hydratase
AL520_RS16820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL520_RS16825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL520_RS16835	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL520_RS16840	COG3395	kinase activity
AL520_RS16850	COG1132	(ABC) transporter
AL520_RS16860	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS16870	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS16885	COG0183	Belongs to the thiolase family
AL520_RS16890	COG1024	Enoyl-CoA hydratase
AL520_RS16890	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_RS16900	COG1024	Enoyl-CoA hydratase
AL520_RS16900	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_RS16910	COG1960	acyl-CoA dehydrogenase activity
AL520_RS16915	COG1309	transcriptional regulator
AL520_RS16925	COG2197	response regulator
AL520_RS16930	COG2197	response regulator
AL520_RS16935	COG0297	glycogen (starch) synthase activity
AL520_RS16940	COG0110	maltose O-acetyltransferase activity
AL520_RS16945	COG0463	Glycosyl transferase, family 2
AL520_RS16970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_RS16990	COG1051	belongs to the nudix hydrolase family
AL520_RS16995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL520_RS17015	COG0166	Belongs to the GPI family
AL520_RS17020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL520_RS17025	COG1045	serine acetyltransferase
AL520_RS17030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL520_RS17035	COG0483	inositol monophosphate 1-phosphatase activity
AL520_RS17045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL520_RS17065	COG0598	Magnesium transport protein CorA
AL520_RS17085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS17090	COG4172	Belongs to the ABC transporter superfamily
AL520_RS17095	COG1846	Transcriptional regulator
AL520_RS17140	COG4964	Belongs to the GSP D family
AL520_RS17195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL520_RS17210	COG3384	dioxygenase
AL520_RS17220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL520_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS17260	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS17265	COG3321	synthase
AL520_RS17265	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS17265	COG0604	alcohol dehydrogenase
AL520_RS17280	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS17300	COG3246	L-lysine catabolic process to acetate
AL520_RS17305	COG0371	Dehydrogenase
AL520_RS17310	COG1802	Transcriptional regulator
AL520_RS17315	COG3959	Transketolase, thiamine diphosphate binding domain
AL520_RS17320	COG3958	Transketolase
AL520_RS17325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL520_RS17335	COG4948	Mandelate Racemase Muconate Lactonizing
AL520_RS17340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS17350	COG0765	amino acid transport
AL520_RS17360	COG2721	sulfolactate sulfo-lyase activity
AL520_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS17375	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL520_RS17380	COG1414	Transcriptional regulator
AL520_RS17395	COG0596	Alpha beta hydrolase
AL520_RS17415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL520_RS17420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL520_RS17425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_RS17430	COG1120	ATPase activity
AL520_RS17445	COG4206	TonB-dependent receptor
AL520_RS17450	COG4206	TonB-dependent receptor
AL520_RS17455	COG4774	siderophore transport
AL520_RS17465	COG1595	DNA-templated transcription, initiation
AL520_RS17470	COG0477	Major facilitator Superfamily
AL520_RS17480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL520_RS17490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL520_RS17515	COG3852	Histidine kinase
AL520_RS17525	COG1058	Belongs to the CinA family
AL520_RS17525	COG1546	Belongs to the CinA family
AL520_RS17540	COG1113	amino acid transport
AL520_RS17555	COG2207	Transcriptional regulator
AL520_RS17560	COG1064	alcohol dehydrogenase
AL520_RS17575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AL520_RS17575	COG3608	succinylglutamate desuccinylase aspartoacylase
AL520_RS17585	COG1850	ribulose-bisphosphate carboxylase activity
AL520_RS17595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_RS17600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_RS17605	COG1609	Transcriptional regulator
AL520_RS17620	COG0500	methyltransferase
AL520_RS17635	COG2199	diguanylate cyclase activity
AL520_RS17640	COG2814	Major facilitator Superfamily
AL520_RS17645	COG0583	DNA-binding transcription factor activity
AL520_RS17675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS17705	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS17720	COG1396	sequence-specific DNA binding
AL520_RS17760	COG0811	peptide transport
AL520_RS17790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_RS17815	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AL520_RS17820	COG1116	anion transmembrane transporter activity
AL520_RS17825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS17830	COG1116	anion transmembrane transporter activity
AL520_RS17830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_RS17835	COG2197	response regulator
AL520_RS17845	COG1131	(ABC) transporter
AL520_RS17850	COG0842	Transport permease protein
AL520_RS17865	COG0183	Belongs to the thiolase family
AL520_RS17890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_RS17895	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS17905	COG0604	alcohol dehydrogenase
AL520_RS17905	COG3321	synthase
AL520_RS17945	COG1272	protein, Hemolysin III
AL520_RS17975	COG2169	Transcriptional regulator
AL520_RS17995	COG2837	iron assimilation
AL520_RS18050	COG1464	Belongs to the NlpA lipoprotein family
AL520_RS18055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL520_RS18060	COG2011	ABC-type metal ion transport system permease component
AL520_RS18095	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS18100	COG3618	amidohydrolase
AL520_RS18115	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AL520_RS18120	COG3153	acetyltransferase
AL520_RS18130	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS18135	COG1473	amidohydrolase
AL520_RS18145	COG1309	transcriptional regulator
AL520_RS18150	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS18165	COG0583	DNA-binding transcription factor activity
AL520_RS18185	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_RS18205	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_RS18215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS18240	COG1522	sequence-specific DNA binding
AL520_RS18285	COG3386	PFAM SMP-30 Gluconolaconase
AL520_RS18310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_RS18320	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS18350	COG0625	glutathione transferase activity
AL520_RS18365	COG3530	Putative quorum-sensing-regulated virulence factor
AL520_RS18375	COG2814	Major facilitator Superfamily
AL520_RS18410	COG0443	Heat shock 70 kDa protein
AL520_RS18415	COG0494	nUDIX hydrolase
AL520_RS18425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL520_RS18430	COG0477	Major facilitator Superfamily
AL520_RS18440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL520_RS18450	COG0542	response to heat
AL520_RS18475	COG5441	Belongs to the UPF0261 family
AL520_RS18480	COG5564	TIM-barrel signal transduction protein
AL520_RS18495	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_RS18510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL520_RS18520	COG1562	ergosterol biosynthetic process
AL520_RS18530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL520_RS18535	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS18545	COG3971	2-oxopent-4-enoate hydratase activity
AL520_RS18560	COG1012	belongs to the aldehyde dehydrogenase family
AL520_RS18565	COG3384	dioxygenase
AL520_RS18595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_RS18605	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS18615	COG2186	Transcriptional regulator
AL520_RS18620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL520_RS18625	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS18640	COG0583	DNA-binding transcription factor activity
AL520_RS18645	COG0268	Binds directly to 16S ribosomal RNA
AL520_RS18655	COG0728	peptidoglycan biosynthetic process
AL520_RS18665	COG0563	adenylate kinase activity
AL520_RS18670	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL520_RS18675	COG2835	tetraacyldisaccharide 4'-kinase activity
AL520_RS18685	COG1663	tetraacyldisaccharide 4'-kinase activity
AL520_RS18695	COG0811	peptide transport
AL520_RS18700	COG1570	exodeoxyribonuclease VII activity
AL520_RS18710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL520_RS18720	COG0038	chloride channel
AL520_RS18725	COG0183	Belongs to the thiolase family
AL520_RS18735	COG1278	Cold shock
AL520_RS18740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL520_RS18745	COG2373	Large extracellular alpha-helical protein
AL520_RS18760	COG2995	paraquat-inducible protein a
AL520_RS18765	COG3008	intermembrane lipid transfer
AL520_RS18775	COG0506	proline dehydrogenase activity
AL520_RS18775	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL520_RS18775	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL520_RS18805	COG2271	Major facilitator Superfamily
AL520_RS18825	COG1764	response to oxidative stress
AL520_RS18830	COG2423	ornithine cyclodeaminase activity
AL520_RS18840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS18845	COG0765	amino acid transport
AL520_RS18850	COG0765	amino acid transport
AL520_RS18855	COG1126	abc transporter atp-binding protein
AL520_RS18860	COG1902	pentaerythritol trinitrate reductase activity
AL520_RS18910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL520_RS18915	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL520_RS18920	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL520_RS18925	COG0196	riboflavin kinase activity
AL520_RS18930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL520_RS18935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL520_RS18935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL520_RS18950	COG0210	DNA helicase
AL520_RS18960	COG1858	cytochrome C peroxidase
AL520_RS18970	COG4771	TonB-dependent receptor
AL520_RS18975	COG4771	TonB-dependent receptor
AL520_RS18990	COG0488	(ABC) transporter
AL520_RS18995	COG2890	protein-(glutamine-N5) methyltransferase activity
AL520_RS19005	COG2171	N-acyltransferase activity
AL520_RS19045	COG2271	Major facilitator Superfamily
AL520_RS19060	COG0277	FAD linked oxidase domain protein
AL520_RS19085	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL520_RS19125	COG0583	DNA-binding transcription factor activity
AL520_RS19135	COG0251	oxidation-reduction process
AL520_RS19160	COG1278	Cold shock
AL520_RS19170	COG1278	Cold shock
AL520_RS19180	COG0501	Belongs to the peptidase M48B family
AL520_RS19185	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL520_RS19190	COG0740	serine-type endopeptidase activity
AL520_RS19195	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL520_RS19200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL520_RS19205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL520_RS19215	COG0556	nucleotide-excision repair
AL520_RS19220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL520_RS19230	COG1104	cysteine desulfurase activity
AL520_RS19235	COG0822	iron-sulfur transferase activity
AL520_RS19240	COG0316	Belongs to the HesB IscA family
AL520_RS19245	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL520_RS19250	COG0443	Heat shock 70 kDa protein
AL520_RS19255	COG0633	Ferredoxin
AL520_RS19260	COG2975	iron-sulfur cluster assembly
AL520_RS19265	COG1803	Methylglyoxal synthase
AL520_RS19275	COG1024	Enoyl-CoA hydratase
AL520_RS19310	COG0183	Belongs to the thiolase family
AL520_RS19315	COG1309	transcriptional regulator
AL520_RS19320	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL520_RS19325	COG3135	benzoate transporter
AL520_RS19340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL520_RS19345	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS19355	COG2271	Major facilitator Superfamily
AL520_RS19380	COG1136	(ABC) transporter
AL520_RS19385	COG0084	hydrolase, TatD family'
AL520_RS19395	COG0745	RESPONSE REGULATOR receiver
AL520_RS19400	COG4771	TonB-dependent receptor
AL520_RS19405	COG4607	ABC-type enterochelin transport system periplasmic component
AL520_RS19410	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_RS19415	COG4605	iron ion homeostasis
AL520_RS19420	COG4604	ABC transporter, ATP-binding protein
AL520_RS19435	COG1595	DNA-templated transcription, initiation
AL520_RS19465	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AL520_RS19470	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS19500	COG0459	protein refolding
AL520_RS19505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL520_RS19515	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL520_RS19540	COG3093	addiction module antidote protein HigA
AL520_RS19560	COG0159	tryptophan synthase activity
AL520_RS19575	COG0583	DNA-binding transcription factor activity
AL520_RS19585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL520_RS19605	COG0613	PHP domain protein
AL520_RS19615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_RS19620	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL520_RS19620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_RS19630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL520_RS19630	COG0047	phosphoribosylformylglycinamidine synthase activity
AL520_RS19675	COG0583	DNA-binding transcription factor activity
AL520_RS19695	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS19720	COG2205	protein histidine kinase activity
AL520_RS19720	COG3292	Two component regulator propeller
AL520_RS19720	COG0745	RESPONSE REGULATOR receiver
AL520_RS19725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS19725	COG0784	Response regulator, receiver
AL520_RS19725	COG2205	protein histidine kinase activity
AL520_RS19725	COG2198	Histidine kinase
AL520_RS19735	COG1309	transcriptional regulator
AL520_RS19750	COG1953	Uracil, thiamine, allantoin
AL520_RS19760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL520_RS19800	COG4774	siderophore transport
AL520_RS19805	COG5001	Diguanylate cyclase
AL520_RS19830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL520_RS19845	COG3618	amidohydrolase
AL520_RS19850	COG0583	DNA-binding transcription factor activity
AL520_RS19860	COG1960	acyl-CoA dehydrogenase activity
AL520_RS19870	COG1024	Enoyl-CoA hydratase
AL520_RS19925	COG4774	siderophore transport
AL520_RS19945	COG1204	response to ionizing radiation
AL520_RS19975	COG0747	negative chemotaxis
AL520_RS19980	COG4608	Belongs to the ABC transporter superfamily
AL520_RS19990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS19995	COG0601	transmembrane transport
AL520_RS20000	COG2072	flavoprotein involved in K transport
AL520_RS20030	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS20035	COG3048	D-serine ammonia-lyase activity
AL520_RS20040	COG0583	DNA-binding transcription factor activity
AL520_RS20060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_RS20070	COG0583	DNA-binding transcription factor activity
AL520_RS20105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL520_RS20105	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_RS20125	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL520_RS20165	COG2207	Transcriptional regulator
AL520_RS20185	COG0640	Transcriptional regulator
AL520_RS20195	COG3321	synthase
AL520_RS20195	COG0604	alcohol dehydrogenase
AL520_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS20205	COG1846	Transcriptional regulator
AL520_RS20225	COG2207	Transcriptional regulator
AL520_RS20245	COG2267	carboxylic ester hydrolase activity
AL520_RS20285	COG0583	DNA-binding transcription factor activity
AL520_RS20310	COG0477	Major facilitator Superfamily
AL520_RS20345	COG0456	acetyltransferase
AL520_RS20360	COG1199	ATP-dependent helicase activity
AL520_RS20375	COG0583	DNA-binding transcription factor activity
AL520_RS20385	COG0154	amidase activity
AL520_RS20390	COG0840	transmembrane signaling receptor activity
AL520_RS20420	COG2203	Gaf domain
AL520_RS20420	COG3706	GGDEF domain
AL520_RS20420	COG4251	negative regulation of phosphorylation
AL520_RS20420	COG5001	Diguanylate cyclase
AL520_RS20425	COG4149	molybdate abc transporter
AL520_RS20430	COG1840	ABC-type Fe3 transport system, periplasmic component
AL520_RS20435	COG3842	ATPase activity
AL520_RS20440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS20445	COG1522	sequence-specific DNA binding
AL520_RS20465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL520_RS20465	COG2010	Cytochrome c
AL520_RS20470	COG1335	isochorismatase
AL520_RS20475	COG2309	aminopeptidase activity
AL520_RS20480	COG0596	Alpha beta hydrolase
AL520_RS20490	COG2080	2 iron, 2 sulfur cluster binding
AL520_RS20495	COG2010	Cytochrome c
AL520_RS20495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL520_RS20500	COG0477	Major facilitator Superfamily
AL520_RS20505	COG1846	Transcriptional regulator
AL520_RS20510	COG2814	Major facilitator Superfamily
AL520_RS20515	COG4771	TonB-dependent receptor
AL520_RS20530	COG0583	DNA-binding transcription factor activity
AL520_RS20545	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL520_RS20555	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS20560	COG1960	acyl-CoA dehydrogenase activity
AL520_RS20565	COG1960	acyl-CoA dehydrogenase activity
AL520_RS20570	COG0183	Belongs to the thiolase family
AL520_RS20575	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_RS20575	COG1024	Enoyl-CoA hydratase
AL520_RS20580	COG0583	DNA-binding transcription factor activity
AL520_RS20605	COG0148	phosphopyruvate hydratase activity
AL520_RS20615	COG2733	membrane
AL520_RS20620	COG2032	superoxide dismutase activity
AL520_RS20625	COG0625	glutathione transferase activity
AL520_RS20820	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AL520_RS20830	COG2885	chlorophyll binding
AL520_RS20860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS20880	COG3971	2-oxopent-4-enoate hydratase activity
AL520_RS20885	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL520_RS20905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL520_RS20910	COG1414	Transcriptional regulator
AL520_RS20920	COG3541	Predicted nucleotidyltransferase
AL520_RS20925	COG1846	Transcriptional regulator
AL520_RS20945	COG0456	acetyltransferase
AL520_RS20955	COG0583	DNA-binding transcription factor activity
AL520_RS20965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL520_RS20975	COG0697	spore germination
AL520_RS20985	COG4941	Belongs to the sigma-70 factor family
AL520_RS20995	COG3795	YCII-related domain
AL520_RS21000	COG3795	YCII-related domain
AL520_RS21005	COG3047	cAMP biosynthetic process
AL520_RS21005	COG2885	chlorophyll binding
AL520_RS21035	COG1683	Conserved Protein
AL520_RS21055	COG1309	transcriptional regulator
AL520_RS21060	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS21070	COG0667	Aldo Keto reductase
AL520_RS21075	COG0477	Major facilitator Superfamily
AL520_RS21085	COG1414	Transcriptional regulator
AL520_RS21095	COG2345	Transcriptional regulator
AL520_RS21100	COG4774	siderophore transport
AL520_RS21120	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL520_RS21180	COG3328	transposase activity
AL520_RS21195	COG0840	transmembrane signaling receptor activity
AL520_RS21205	COG3038	cytochrome b561
AL520_RS21210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL520_RS21215	COG1309	transcriptional regulator
AL520_RS21230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL520_RS21235	COG0436	Aminotransferase
AL520_RS21240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS21245	COG0765	amino acid transport
AL520_RS21250	COG0765	amino acid transport
AL520_RS21275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL520_RS21285	COG0667	Aldo Keto reductase
AL520_RS21310	COG0587	DNA-directed DNA polymerase activity
AL520_RS21330	COG0833	amino acid
AL520_RS21335	COG0400	carboxylic ester hydrolase activity
AL520_RS21345	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS21355	COG0028	Belongs to the TPP enzyme family
AL520_RS21370	COG1566	PFAM secretion protein HlyD family protein
AL520_RS21380	COG1289	transmembrane transporter activity
AL520_RS21390	COG0720	synthase
AL520_RS21395	COG0602	queuosine metabolic process
AL520_RS21410	COG1902	pentaerythritol trinitrate reductase activity
AL520_RS21440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL520_RS21455	COG0842	Transport permease protein
AL520_RS21460	COG1131	(ABC) transporter
AL520_RS21475	COG2130	NADP-dependent
AL520_RS21500	COG3842	ATPase activity
AL520_RS21505	COG3842	ATPase activity
AL520_RS21515	COG0395	ABC-type sugar transport system, permease component
AL520_RS21550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS21575	COG3634	alkyl hydroperoxide reductase activity
AL520_RS21580	COG1959	2 iron, 2 sulfur cluster binding
AL520_RS21590	COG0583	DNA-binding transcription factor activity
AL520_RS21595	COG1960	acyl-CoA dehydrogenase activity
AL520_RS21630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS21635	COG0420	3'-5' exonuclease activity
AL520_RS21660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL520_RS21660	COG2111	Na H antiporter
AL520_RS21665	COG1006	Multisubunit Na H antiporter MnhC subunit
AL520_RS21670	COG0651	ATP synthesis coupled electron transport
AL520_RS21675	COG1863	multisubunit Na H antiporter MnhE subunit
AL520_RS21680	COG2212	antiporter activity
AL520_RS21685	COG1320	monovalent cation:proton antiporter activity
AL520_RS21700	COG0590	tRNA wobble adenosine to inosine editing
AL520_RS21705	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL520_RS21710	COG0488	(ABC) transporter
AL520_RS21745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_RS21750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL520_RS21760	COG2252	PERMEase
AL520_RS21765	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL520_RS21770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL520_RS21780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL520_RS21805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL520_RS21810	COG0789	Transcriptional regulator
AL520_RS21825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL520_RS21825	COG0678	peroxiredoxin activity
AL520_RS21835	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL520_RS21840	COG0584	glycerophosphoryl diester phosphodiesterase
AL520_RS21850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_RS21860	COG4181	ATPase activity
AL520_RS21870	COG1178	ABC-type Fe3 transport system permease component
AL520_RS21875	COG3842	ATPase activity
AL520_RS21880	COG0583	DNA-binding transcription factor activity
AL520_RS21885	COG0560	Phosphoserine phosphatase
AL520_RS21900	COG0583	DNA-binding transcription factor activity
AL520_RS21915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_RS21930	COG0583	DNA-binding transcription factor activity
AL520_RS21935	COG4336	lyase activity
AL520_RS21965	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS21985	COG2816	NAD+ diphosphatase activity
AL520_RS22005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS22010	COG0765	amino acid transport
AL520_RS22015	COG1126	abc transporter atp-binding protein
AL520_RS22020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL520_RS22025	COG1758	RNA polymerase activity
AL520_RS22030	COG0194	GDP metabolic process
AL520_RS22035	COG3258	Cytochrome c
AL520_RS22040	COG2863	cytochrome
AL520_RS22045	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS22050	COG2831	hemolysin activation secretion protein
AL520_RS22055	COG3210	domain, Protein
AL520_RS22070	COG0791	NLP P60 protein
AL520_RS22085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL520_RS22090	COG0833	amino acid
AL520_RS22095	COG1561	YicC-like family, N-terminal region
AL520_RS22100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL520_RS22110	COG1960	acyl-CoA dehydrogenase activity
AL520_RS22125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL520_RS22130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL520_RS22135	COG0174	glutamine synthetase
AL520_RS22145	COG2204	response regulator
AL520_RS22150	COG0583	DNA-binding transcription factor activity
AL520_RS22155	COG1741	Belongs to the pirin family
AL520_RS22160	COG1741	Belongs to the pirin family
AL520_RS22165	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL520_RS22170	COG1690	Belongs to the RtcB family
AL520_RS22180	COG3842	ATPase activity
AL520_RS22185	COG4149	molybdate abc transporter
AL520_RS22190	COG1840	ABC-type Fe3 transport system, periplasmic component
AL520_RS22200	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS22215	COG0583	DNA-binding transcription factor activity
AL520_RS22235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL520_RS22245	COG0783	Belongs to the Dps family
AL520_RS22255	COG0457	Tetratricopeptide repeat
AL520_RS22260	COG0438	transferase activity, transferring glycosyl groups
AL520_RS22285	COG1560	Kdo2-lipid A biosynthetic process
AL520_RS22285	COG4783	chaperone-mediated protein folding
AL520_RS22305	COG0745	RESPONSE REGULATOR receiver
AL520_RS22310	COG2205	protein histidine kinase activity
AL520_RS22325	COG3842	ATPase activity
AL520_RS22330	COG0395	ABC-type sugar transport system, permease component
AL520_RS22335	COG1175	transmembrane transport
AL520_RS22340	COG1653	transport
AL520_RS22350	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL520_RS22360	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_RS22390	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_RS22400	COG0583	DNA-binding transcription factor activity
AL520_RS22405	COG0625	glutathione transferase activity
AL520_RS22410	COG2133	pyrroloquinoline quinone binding
AL520_RS22420	COG0697	spore germination
AL520_RS22425	COG2363	Small membrane protein
AL520_RS22440	COG1414	Transcriptional regulator
AL520_RS22445	COG0010	Belongs to the arginase family
AL520_RS22450	COG1464	Belongs to the NlpA lipoprotein family
AL520_RS22460	COG2814	Major facilitator Superfamily
AL520_RS22470	COG1408	metallophosphoesterase
AL520_RS22500	COG0688	phosphatidylethanolamine metabolic process
AL520_RS22510	COG0488	(ABC) transporter
AL520_RS22535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS22540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL520_RS22545	COG3300	MHYT domain
AL520_RS22545	COG5001	Diguanylate cyclase
AL520_RS22560	COG2814	Major facilitator Superfamily
AL520_RS22590	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL520_RS22595	COG2204	response regulator
AL520_RS22630	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS22650	COG0693	protein deglycase activity
AL520_RS22665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_RS22675	COG1289	transmembrane transporter activity
AL520_RS22680	COG5001	Diguanylate cyclase
AL520_RS22680	COG3300	MHYT domain
AL520_RS22715	COG3415	Transposase
AL520_RS22715	COG2801	Transposase and inactivated derivatives
AL520_RS22735	COG1253	flavin adenine dinucleotide binding
AL520_RS22745	COG2205	protein histidine kinase activity
AL520_RS22800	COG3706	GGDEF domain
AL520_RS22805	COG0789	Transcriptional regulator
AL520_RS22815	COG3706	GGDEF domain
AL520_RS22865	COG0628	permease
AL520_RS22890	COG0531	amino acid
AL520_RS22900	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_RS22905	COG4608	Belongs to the ABC transporter superfamily
AL520_RS22910	COG0444	Belongs to the ABC transporter superfamily
AL520_RS22915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS22920	COG0601	transmembrane transport
AL520_RS22925	COG0747	negative chemotaxis
AL520_RS22955	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL520_RS22970	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL520_RS22980	COG2146	nitrite reductase [NAD(P)H] activity
AL520_RS22995	COG3971	2-oxopent-4-enoate hydratase activity
AL520_RS23025	COG0625	glutathione transferase activity
AL520_RS23040	COG0477	Major facilitator Superfamily
AL520_RS23050	COG0579	oxidoreductase
AL520_RS23070	COG1280	lysine exporter protein (LysE YggA)
AL520_RS23100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL520_RS23105	COG0589	response to stress
AL520_RS23115	COG0589	response to stress
AL520_RS23125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL520_RS23145	COG0668	transmembrane transport
AL520_RS23155	COG0166	Belongs to the GPI family
AL520_RS23165	COG3685	Protein conserved in bacteria
AL520_RS23180	COG0387	Pfam Sodium calcium exchanger
AL520_RS23185	COG3568	Endonuclease Exonuclease Phosphatase
AL520_RS23190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL520_RS23195	COG0392	lysyltransferase activity
AL520_RS23200	COG0297	glycogen (starch) synthase activity
AL520_RS23205	COG0366	Alpha amylase catalytic
AL520_RS23210	COG0366	Alpha amylase catalytic
AL520_RS23215	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL520_RS23225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL520_RS23230	COG1640	4-alpha-glucanotransferase
AL520_RS23240	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AL520_RS23270	COG4771	TonB-dependent receptor
AL520_RS23280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL520_RS23285	COG1595	DNA-templated transcription, initiation
AL520_RS23295	COG4774	siderophore transport
AL520_RS23300	COG4774	siderophore transport
AL520_RS23315	COG2358	TRAP transporter, solute receptor (TAXI family
AL520_RS23320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS23325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS23335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL520_RS23340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL520_RS23340	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_RS23350	COG1276	copper resistance
AL520_RS23370	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS23375	COG2721	sulfolactate sulfo-lyase activity
AL520_RS23400	COG0745	RESPONSE REGULATOR receiver
AL520_RS23410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_RS23415	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL520_RS23420	COG1120	ATPase activity
AL520_RS23425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL520_RS23440	COG0586	Pfam SNARE associated Golgi protein
AL520_RS23445	COG0390	transport system, permease component
AL520_RS23450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL520_RS23455	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AL520_RS23495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL520_RS23500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_RS23505	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_RS23510	COG1120	ATPase activity
AL520_RS23515	COG1126	abc transporter atp-binding protein
AL520_RS23520	COG0765	amino acid transport
AL520_RS23525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS23530	COG2070	2-Nitropropane dioxygenase
AL520_RS23535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_RS23545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL520_RS23575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL520_RS23580	COG0583	DNA-binding transcription factor activity
AL520_RS23600	COG4566	intracellular signal transduction
AL520_RS23625	COG4774	siderophore transport
AL520_RS23665	COG0583	DNA-binding transcription factor activity
AL520_RS23685	COG1126	abc transporter atp-binding protein
AL520_RS23695	COG0765	amino acid transport
AL520_RS23700	COG0436	Aminotransferase
AL520_RS23705	COG0277	FAD linked oxidase domain protein
AL520_RS23730	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL520_RS23755	COG0251	oxidation-reduction process
AL520_RS23790	COG4948	Mandelate Racemase Muconate Lactonizing
AL520_RS23800	COG1802	Transcriptional regulator
AL520_RS23805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_RS23820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL520_RS23850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS23855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_RS23860	COG1116	anion transmembrane transporter activity
AL520_RS23895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS23900	COG4597	amino acid ABC transporter
AL520_RS23905	COG3154	lipid carrier protein
AL520_RS23910	COG0826	peptidase U32
AL520_RS23915	COG0826	peptidase U32
AL520_RS23920	COG2197	response regulator
AL520_RS23925	COG3850	Histidine kinase
AL520_RS23930	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL520_RS23935	COG0288	reversible hydration of carbon dioxide
AL520_RS23940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL520_RS23945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_RS23950	COG2181	nitrate reductase activity
AL520_RS23955	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL520_RS23960	COG1140	nitrate reductase beta subunit
AL520_RS23965	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL520_RS23970	COG2223	nitrite transmembrane transporter activity
AL520_RS23990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_RS23995	COG0583	DNA-binding transcription factor activity
AL520_RS24005	COG0583	DNA-binding transcription factor activity
AL520_RS24015	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS24045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS24065	COG2070	2-Nitropropane dioxygenase
AL520_RS24070	COG5002	protein histidine kinase activity
AL520_RS24075	COG0745	RESPONSE REGULATOR receiver
AL520_RS24080	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AL520_RS24085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL520_RS24095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL520_RS24100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL520_RS24115	COG0783	Belongs to the Dps family
AL520_RS24135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS24140	COG0697	spore germination
AL520_RS24145	COG2879	small protein
AL520_RS24150	COG1966	Carbon starvation protein
AL520_RS24170	COG0697	spore germination
AL520_RS24175	COG0583	DNA-binding transcription factor activity
AL520_RS24180	COG2801	Transposase and inactivated derivatives
AL520_RS24180	COG3415	Transposase
AL520_RS24185	COG4521	taurine ABC transporter
AL520_RS24190	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL520_RS24195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_RS24220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_RS24230	COG0523	cobalamin synthesis protein
AL520_RS24235	COG1228	amidohydrolase
AL520_RS24240	COG4172	Belongs to the ABC transporter superfamily
AL520_RS24245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS24250	COG0601	transmembrane transport
AL520_RS24255	COG0747	negative chemotaxis
AL520_RS24270	COG1414	Transcriptional regulator
AL520_RS24275	COG0513	Belongs to the DEAD box helicase family
AL520_RS24295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS24305	COG0840	transmembrane signaling receptor activity
AL520_RS24315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL520_RS24345	COG2814	Major facilitator Superfamily
AL520_RS24350	COG0386	Belongs to the glutathione peroxidase family
AL520_RS24355	COG1522	sequence-specific DNA binding
AL520_RS24365	COG0625	glutathione transferase activity
AL520_RS24380	COG0095	Lipoate-protein ligase
AL520_RS24390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL520_RS24400	COG0010	Belongs to the arginase family
AL520_RS24405	COG1126	abc transporter atp-binding protein
AL520_RS24410	COG0765	amino acid transport
AL520_RS24415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_RS24430	COG0084	hydrolase, TatD family'
AL520_RS24435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL520_RS24440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL520_RS24470	COG1024	Enoyl-CoA hydratase
AL520_RS24470	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_RS24480	COG2914	Belongs to the UPF0125 (RnfH) family
AL520_RS24485	COG2867	negative regulation of translational initiation
AL520_RS24490	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL520_RS24510	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_RS24510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL520_RS24515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL520_RS24515	COG2169	Transcriptional regulator
AL520_RS24555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL520_RS24560	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL520_RS24575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL520_RS24580	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL520_RS24585	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL520_RS24590	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL520_RS24595	COG0750	zinc metalloprotease
AL520_RS24600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL520_RS24610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL520_RS24615	COG0233	cytoplasmic translational termination
AL520_RS24620	COG0528	UMP kinase activity
AL520_RS24625	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL520_RS24630	COG0052	Belongs to the universal ribosomal protein uS2 family
AL520_RS24635	COG0024	Methionine aminopeptidase
AL520_RS24640	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL520_RS24650	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL520_RS24660	COG1451	nucleotide metabolic process
AL520_RS24670	COG1286	toxin biosynthetic process
AL520_RS24680	COG0285	dihydrofolate synthase activity
AL520_RS24690	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS24695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS24705	COG1414	Transcriptional regulator
AL520_RS24715	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL520_RS24735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL520_RS24745	COG1677	Flagellar hook-basal body complex protein FliE
AL520_RS24750	COG1766	The M ring may be actively involved in energy transduction
AL520_RS24755	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL520_RS24780	COG1580	Controls the rotational direction of flagella during chemotaxis
AL520_RS24790	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL520_RS24815	COG0840	transmembrane signaling receptor activity
AL520_RS24820	COG0840	transmembrane signaling receptor activity
AL520_RS24830	COG0840	transmembrane signaling receptor activity
AL520_RS24835	COG0840	transmembrane signaling receptor activity
AL520_RS24870	COG4787	bacterial-type flagellum-dependent cell motility
AL520_RS24885	COG1558	bacterial-type flagellum-dependent cell motility
AL520_RS24900	COG2747	anti-sigma28 factor FlgM
AL520_RS24930	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL520_RS24935	COG0745	RESPONSE REGULATOR receiver
AL520_RS24940	COG2201	protein-glutamate methylesterase activity
AL520_RS24945	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL520_RS24950	COG0840	transmembrane signaling receptor activity
AL520_RS24955	COG0835	chemotaxis
AL520_RS24965	COG0745	RESPONSE REGULATOR receiver
AL520_RS24990	COG1191	sigma factor activity
AL520_RS24995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL520_RS24995	COG4797	methyltransferase
AL520_RS25025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL520_RS25030	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL520_RS25035	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL520_RS25045	COG4566	intracellular signal transduction
AL520_RS25050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL520_RS25055	COG0339	signal peptide processing
AL520_RS25065	COG1999	signal sequence binding
AL520_RS25070	COG2261	transglycosylase associated protein
AL520_RS25090	COG0583	DNA-binding transcription factor activity
AL520_RS25095	COG1187	pseudouridine synthase activity
AL520_RS25100	COG3161	chorismate lyase activity
AL520_RS25105	COG0477	Major facilitator Superfamily
AL520_RS25125	COG4681	YaeQ
AL520_RS25130	COG4172	Belongs to the ABC transporter superfamily
AL520_RS25135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS25140	COG0601	transmembrane transport
AL520_RS25145	COG0747	negative chemotaxis
AL520_RS25155	COG0583	DNA-binding transcription factor activity
AL520_RS25190	COG2165	general secretion pathway protein
AL520_RS25265	COG0668	transmembrane transport
AL520_RS25270	COG0165	Argininosuccinate lyase
AL520_RS25290	COG0022	dehydrogenase e1 component
AL520_RS25300	COG4774	siderophore transport
AL520_RS25325	COG0789	Transcriptional regulator
AL520_RS25335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL520_RS25345	COG2271	Major facilitator Superfamily
AL520_RS25355	COG0307	riboflavin synthase, alpha
AL520_RS25370	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS25450	COG2070	2-Nitropropane dioxygenase
AL520_RS25500	COG0154	amidase activity
AL520_RS25505	COG2814	Major facilitator Superfamily
AL520_RS25530	COG2814	Major facilitator Superfamily
AL520_RS25545	COG0583	DNA-binding transcription factor activity
AL520_RS25560	COG0583	DNA-binding transcription factor activity
AL520_RS25585	COG2059	Chromate
AL520_RS25620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_RS25630	COG5265	(ABC) transporter
AL520_RS25675	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS25680	COG2188	Transcriptional regulator
AL520_RS25695	COG0477	Major facilitator Superfamily
AL520_RS25700	COG0235	Class ii aldolase
AL520_RS25745	COG2610	gluconate transmembrane transporter activity
AL520_RS25750	COG0583	DNA-binding transcription factor activity
AL520_RS25755	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS25760	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AL520_RS25775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_RS25800	COG1024	Enoyl-CoA hydratase
AL520_RS25805	COG5001	Diguanylate cyclase
AL520_RS25810	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS25815	COG0129	dihydroxy-acid dehydratase activity
AL520_RS25825	COG0583	DNA-binding transcription factor activity
AL520_RS25830	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_RS25835	COG3246	L-lysine catabolic process to acetate
AL520_RS25855	COG3381	protein complex oligomerization
AL520_RS25875	COG4133	protoheme IX ABC transporter activity
AL520_RS25880	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL520_RS25895	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL520_RS25905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_RS25910	COG3088	subunit of a heme lyase
AL520_RS25935	COG0583	DNA-binding transcription factor activity
AL520_RS25960	COG4172	Belongs to the ABC transporter superfamily
AL520_RS25965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL520_RS25970	COG0583	DNA-binding transcription factor activity
AL520_RS25975	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS25980	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS25995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_RS26005	COG1063	alcohol dehydrogenase
AL520_RS26030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL520_RS26035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_RS26040	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS26045	COG2207	Transcriptional regulator
AL520_RS26080	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS26090	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AL520_RS26095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL520_RS26105	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS26110	COG1024	Enoyl-CoA hydratase
AL520_RS26115	COG0534	Mate efflux family protein
AL520_RS26130	COG0697	spore germination
AL520_RS26135	COG0697	spore germination
AL520_RS26150	COG1280	lysine exporter protein (LysE YggA)
AL520_RS26165	COG1280	lysine exporter protein (LysE YggA)
AL520_RS26170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL520_RS26190	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_RS26195	COG1960	acyl-CoA dehydrogenase activity
AL520_RS26215	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL520_RS26220	COG2814	Major facilitator Superfamily
AL520_RS26235	COG0625	glutathione transferase activity
AL520_RS26250	COG2814	Major facilitator Superfamily
AL520_RS26255	COG0583	DNA-binding transcription factor activity
AL520_RS26275	COG0506	proline dehydrogenase activity
AL520_RS26280	COG0697	spore germination
AL520_RS26290	COG1959	2 iron, 2 sulfur cluster binding
AL520_RS26315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL520_RS26320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL520_RS26330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL520_RS26370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL520_RS26380	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS26385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL520_RS26395	COG1610	YqeY-like protein
AL520_RS26430	COG0457	Tetratricopeptide repeat
AL520_RS26435	COG0726	polysaccharide deacetylase
AL520_RS26435	COG1649	PFAM Uncharacterised BCR, COG1649
AL520_RS26440	COG1215	transferase activity, transferring glycosyl groups
AL520_RS26450	COG2223	nitrite transmembrane transporter activity
AL520_RS26455	COG1917	Cupin 2, conserved barrel domain protein
AL520_RS26455	COG4977	sequence-specific DNA binding
AL520_RS26465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL520_RS26480	COG0656	L-ascorbic acid biosynthetic process
AL520_RS26485	COG5265	(ABC) transporter
AL520_RS26515	COG1116	anion transmembrane transporter activity
AL520_RS26540	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS26545	COG0583	DNA-binding transcription factor activity
AL520_RS26575	COG1522	sequence-specific DNA binding
AL520_RS26625	COG0384	phenazine biosynthesis protein PhzF
AL520_RS26665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL520_RS26665	COG0072	phenylalanine-tRNA ligase activity
AL520_RS26670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL520_RS26675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL520_RS26680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL520_RS26690	COG2960	long-chain fatty acid transporting porin activity
AL520_RS26700	COG0347	Belongs to the P(II) protein family
AL520_RS26705	COG0004	ammonium transporteR
AL520_RS26710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL520_RS26715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL520_RS26730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL520_RS26735	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL520_RS26745	COG2197	response regulator
AL520_RS26750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL520_RS26780	COG1012	belongs to the aldehyde dehydrogenase family
AL520_RS26790	COG0601	transmembrane transport
AL520_RS26795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS26820	COG1609	Transcriptional regulator
AL520_RS26825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL520_RS26830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_RS26835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_RS26840	COG0129	dihydroxy-acid dehydratase activity
AL520_RS26845	COG0657	acetylesterase activity
AL520_RS26845	COG2755	lipolytic protein G-D-S-L family
AL520_RS26890	COG0135	phosphoribosylanthranilate isomerase activity
AL520_RS26895	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL520_RS26900	COG0101	tRNA pseudouridine synthase activity
AL520_RS26910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL520_RS26940	COG2274	protein secretion by the type I secretion system
AL520_RS26945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_RS27000	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL520_RS27010	COG3706	GGDEF domain
AL520_RS27025	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL520_RS27035	COG1295	ribonuclease BN
AL520_RS27045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL520_RS27075	COG4964	Belongs to the GSP D family
AL520_RS27105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL520_RS27105	COG2755	lipolytic protein G-D-S-L family
AL520_RS27120	COG0438	transferase activity, transferring glycosyl groups
AL520_RS27295	COG5410	chromosome segregation
AL520_RS27310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL520_RS27315	COG1121	(ABC) transporter
AL520_RS27335	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AL520_RS27425	COG0419	ATPase involved in DNA repair
AL520_RS27475	COG0697	spore germination
AL520_RS27590	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL520_RS27600	COG0628	permease
AL520_RS27630	COG3909	cytochrome
AL520_RS27640	COG0625	glutathione transferase activity
AL520_RS27645	COG0730	response to heat
AL520_RS27650	COG0482	sulfurtransferase activity
AL520_RS27655	COG0583	DNA-binding transcription factor activity
AL520_RS27685	COG0247	lactate metabolic process
AL520_RS27690	COG0277	FAD linked oxidase domain protein
AL520_RS27695	COG0277	FAD linked oxidase domain protein
AL520_RS27700	COG0277	FAD linked oxidase domain protein
AL520_RS27705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL520_RS27710	COG0312	modulator of DNA gyrase
AL520_RS27725	COG0308	aminopeptidase N
AL520_RS27730	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL520_RS27750	COG0436	Aminotransferase
AL520_RS27760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL520_RS27765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL520_RS27785	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_RS27800	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS27815	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS27845	COG0181	hydroxymethylbilane synthase activity
AL520_RS27850	COG0861	Integral membrane protein TerC family
AL520_RS27855	COG0861	Integral membrane protein TerC family
AL520_RS27860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL520_RS27865	COG0045	succinate-CoA ligase (ADP-forming) activity
AL520_RS27890	COG2137	regulation of response to DNA damage stimulus
AL520_RS27895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL520_RS27930	COG0540	Belongs to the ATCase OTCase family
AL520_RS27960	COG0493	'glutamate synthase
AL520_RS27980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_RS28015	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL520_RS28030	COG0305	Participates in initiation and elongation during chromosome replication
AL520_RS28040	COG0359	binds to the 23S rRNA
AL520_RS28045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL520_RS28050	COG2965	DNA replication, synthesis of RNA primer
AL520_RS28055	COG0360	Binds together with S18 to 16S ribosomal RNA
AL520_RS28060	COG3739	integral membrane protein
AL520_RS28065	COG1469	GTP cyclohydrolase I activity
AL520_RS28075	COG0142	geranyltranstransferase activity
AL520_RS28080	COG1722	exodeoxyribonuclease VII activity
AL520_RS28090	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS28110	COG1840	ABC-type Fe3 transport system, periplasmic component
AL520_RS28115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL520_RS28125	COG3842	ATPase activity
AL520_RS28130	COG0583	DNA-binding transcription factor activity
AL520_RS28150	COG0501	Belongs to the peptidase M48B family
AL520_RS28155	COG1760	l-serine dehydratase
AL520_RS28160	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL520_RS28165	COG3415	Transposase
AL520_RS28165	COG2801	Transposase and inactivated derivatives
AL520_RS28170	COG3328	transposase activity
AL520_RS28180	COG0412	Dienelactone hydrolase
AL520_RS28190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL520_RS28190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL520_RS28195	COG1611	Belongs to the LOG family
AL520_RS28200	COG1473	amidohydrolase
AL520_RS28205	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_RS28225	COG1217	gtp-binding protein TYPA
AL520_RS28230	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL520_RS28235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL520_RS28240	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL520_RS28245	COG0195	Participates in both transcription termination and antitermination
AL520_RS28245	COG2251	uridine kinase activity
AL520_RS28250	COG0779	Required for maturation of 30S ribosomal subunits
AL520_RS28255	COG1187	pseudouridine synthase activity
AL520_RS28260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL520_RS28270	COG0583	DNA-binding transcription factor activity
AL520_RS28275	COG0523	cobalamin synthesis protein
AL520_RS28280	COG0523	cobalamin synthesis protein
AL520_RS28305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL520_RS28310	COG0625	glutathione transferase activity
AL520_RS28315	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL520_RS28325	COG2003	Belongs to the UPF0758 family
AL520_RS28330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL520_RS28335	COG3483	tryptophan 2,3-dioxygenase activity
AL520_RS28350	COG0534	Mate efflux family protein
AL520_RS28360	COG2050	protein possibly involved in aromatic compounds catabolism
AL520_RS28365	COG1024	Enoyl-CoA hydratase
AL520_RS28370	COG1012	belongs to the aldehyde dehydrogenase family
AL520_RS28375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL520_RS28380	COG2151	metal-sulfur cluster biosynthetic enzyme
AL520_RS28385	COG3396	Phenylacetate-CoA oxygenase
AL520_RS28390	COG3460	Phenylacetate-CoA oxygenase
AL520_RS28395	COG3396	Phenylacetate-CoA oxygenase
AL520_RS28400	COG3327	negative regulation of DNA-templated transcription, initiation
AL520_RS28405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL520_RS28410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL520_RS28415	COG0501	Belongs to the peptidase M48B family
AL520_RS28420	COG1162	GTPase activity
AL520_RS28430	COG0335	large ribosomal subunit rRNA binding
AL520_RS28460	COG0175	sulfate reduction
AL520_RS28470	COG4208	sulfate ABC transporter
AL520_RS28475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL520_RS28485	COG0450	alkyl hydroperoxide reductase
AL520_RS28490	COG1960	acyl-CoA dehydrogenase activity
AL520_RS28495	COG2985	domain, Protein
AL520_RS28520	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL520_RS28525	COG2951	lytic endotransglycosylase activity
AL520_RS28555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_RS28560	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL520_RS28565	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL520_RS28585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL520_RS28590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL520_RS28600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL520_RS28610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL520_RS28625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL520_RS28650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL520_RS28660	COG1215	transferase activity, transferring glycosyl groups
AL520_RS28680	COG1696	Membrane protein involved in D-alanine export
AL520_RS28690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL520_RS28700	COG1960	acyl-CoA dehydrogenase activity
AL520_RS28715	COG2951	lytic endotransglycosylase activity
AL520_RS28720	COG2258	MOSC domain
AL520_RS28725	COG2833	Protein of unknown function (DUF455)
AL520_RS28740	COG1132	(ABC) transporter
AL520_RS28745	COG0189	ligase activity
AL520_RS28745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL520_RS28750	COG0189	ligase activity
AL520_RS28750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL520_RS28755	COG3237	CsbD-like
AL520_RS28765	COG2823	Periplasmic or secreted lipoprotein
AL520_RS28815	COG2831	hemolysin activation secretion protein
AL520_RS28840	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AL520_RS28845	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_RS28850	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL520_RS28855	COG1496	oxidoreductase activity
AL520_RS28860	COG0564	pseudouridine synthase activity
AL520_RS28870	COG1199	ATP-dependent helicase activity
AL520_RS28875	COG2183	response to ionizing radiation
AL520_RS28910	COG4774	siderophore transport
AL520_RS28915	COG3712	iron ion homeostasis
AL520_RS28920	COG1595	DNA-templated transcription, initiation
AL520_RS28925	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL520_RS28930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL520_RS28935	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL520_RS28940	COG0567	Dehydrogenase, E1 component
AL520_RS28945	COG1522	sequence-specific DNA binding
AL520_RS28950	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL520_RS28965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL520_RS28970	COG1297	OPT oligopeptide transporter protein
AL520_RS28980	COG0281	malic enzyme
AL520_RS28980	COG0280	phosphate acetyltransferase
AL520_RS28995	COG0372	Belongs to the citrate synthase family
AL520_RS29000	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL520_RS29005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL520_RS29010	COG1053	succinate dehydrogenase
AL520_RS29015	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL520_RS29020	COG2009	succinate dehydrogenase
AL520_RS29025	COG2188	Transcriptional regulator
AL520_RS29030	COG0039	L-malate dehydrogenase activity
AL520_RS29050	COG1981	membrane
AL520_RS29090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL520_RS29100	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL520_RS29115	COG0148	phosphopyruvate hydratase activity
AL520_RS29125	COG0504	CTP synthase activity
AL520_RS29150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_RS29160	COG0747	negative chemotaxis
AL520_RS29165	COG4172	Belongs to the ABC transporter superfamily
AL520_RS29170	COG1446	asparaginase
AL520_RS29180	COG2153	protein acetylation
AL520_RS29220	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL520_RS29225	COG0697	spore germination
AL520_RS29230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL520_RS29240	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AL520_RS29245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL520_RS29250	COG0791	NLP P60 protein
AL520_RS29260	COG0583	DNA-binding transcription factor activity
AL520_RS29285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL520_RS29305	COG0667	Aldo Keto reductase
AL520_RS29325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL520_RS29335	COG1381	Involved in DNA repair and RecF pathway recombination
AL520_RS29340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL520_RS29345	COG0571	ribonuclease III activity
AL520_RS29350	COG0681	Belongs to the peptidase S26 family
AL520_RS29360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL520_RS29385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL520_RS29390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL520_RS29400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL520_RS29405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL520_RS29415	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL520_RS29425	COG0424	maF-like protein
AL520_RS29435	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL520_RS29440	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL520_RS29445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL520_RS29450	COG0546	phosphoglycolate phosphatase activity
AL520_RS29455	COG0564	pseudouridine synthase activity
AL520_RS29460	COG1530	ribonuclease E activity
AL520_RS29465	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL520_RS29470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL520_RS29475	COG0159	tryptophan synthase activity
AL520_RS29485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL520_RS29495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL520_RS29500	COG3228	Belongs to the MtfA family
AL520_RS29510	COG0251	oxidation-reduction process
AL520_RS29515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL520_RS29520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL520_RS29535	COG2878	Part of a membrane complex involved in electron transport
AL520_RS29540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL520_RS29610	COG1268	BioY protein
AL520_RS29615	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AL520_RS29620	COG1122	ATPase activity
AL520_RS29625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL520_RS29630	COG2917	probably involved in intracellular septation
AL520_RS29640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_RS29645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL520_RS29655	COG1196	nuclear chromosome segregation
AL520_RS29660	COG0477	Major facilitator Superfamily
AL520_RS29665	COG1573	uracil-dna glycosylase
AL520_RS29670	COG1214	PFAM Peptidase M22, glycoprotease
AL520_RS29685	COG0450	alkyl hydroperoxide reductase
AL520_RS29690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL520_RS29700	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL520_RS29705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL520_RS29710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL520_RS29715	COG0560	Phosphoserine phosphatase
AL520_RS29735	COG4774	siderophore transport
AL520_RS29745	COG1007	ATP synthesis coupled electron transport
AL520_RS29760	COG0713	ATP synthesis coupled electron transport
AL520_RS29770	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL520_RS29775	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL520_RS29780	COG1034	ATP synthesis coupled electron transport
AL520_RS29790	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL520_RS29795	COG0649	NAD binding
AL520_RS29800	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL520_RS29805	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL520_RS29810	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL520_RS29815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_RS29840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL520_RS29860	COG0583	DNA-binding transcription factor activity
AL520_RS29870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_RS29875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_RS29895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_RS29900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_RS29905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL520_RS29920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_RS29960	COG0747	negative chemotaxis