locus-tag	class	description
Axylo_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Axylo_RS00010	COG0592	DNA-directed DNA polymerase activity
Axylo_RS00020	COG0583	DNA-binding transcription factor activity
Axylo_RS00045	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Axylo_RS00055	COG0583	DNA-binding transcription factor activity
Axylo_RS00060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS00065	COG0765	amino acid transport
Axylo_RS00070	COG0765	amino acid transport
Axylo_RS00075	COG1126	abc transporter atp-binding protein
Axylo_RS00110	COG3842	ATPase activity
Axylo_RS00115	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_RS00120	COG1177	transmembrane transport
Axylo_RS00135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS00175	COG1609	Transcriptional regulator
Axylo_RS00185	COG3842	ATPase activity
Axylo_RS00190	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_RS00195	COG1177	transmembrane transport
Axylo_RS00220	COG0251	oxidation-reduction process
Axylo_RS00230	COG3210	domain, Protein
Axylo_RS00245	COG0402	S-adenosylhomocysteine deaminase activity
Axylo_RS00255	COG4603	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS00260	COG3845	ABC transporter
Axylo_RS00265	COG1744	ABC transporter substrate-binding protein PnrA-like
Axylo_RS00275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Axylo_RS00290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Axylo_RS00305	COG2814	Major facilitator Superfamily
Axylo_RS00320	COG3781	membrane
Axylo_RS00325	COG1522	sequence-specific DNA binding
Axylo_RS00330	COG0028	Belongs to the TPP enzyme family
Axylo_RS00335	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS00340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_RS00365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Axylo_RS00370	COG2922	Belongs to the Smg family
Axylo_RS00380	COG2358	TRAP transporter, solute receptor (TAXI family
Axylo_RS00400	COG0765	amino acid transport
Axylo_RS00405	COG0765	amino acid transport
Axylo_RS00410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS00415	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS00420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Axylo_RS00430	COG4977	sequence-specific DNA binding
Axylo_RS00435	COG2814	Major facilitator Superfamily
Axylo_RS00450	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Axylo_RS00460	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Axylo_RS00470	COG3339	Conserved Protein
Axylo_RS00480	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS00520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Axylo_RS00525	COG0183	Belongs to the thiolase family
Axylo_RS00530	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
Axylo_RS00535	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS00540	COG1473	amidohydrolase
Axylo_RS00550	COG1742	UPF0060 membrane protein
Axylo_RS00565	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS00590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Axylo_RS00600	COG0018	arginyl-trna synthetase
Axylo_RS00615	COG0395	ABC-type sugar transport system, permease component
Axylo_RS00620	COG1175	transmembrane transport
Axylo_RS00625	COG1653	transport
Axylo_RS00635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Axylo_RS00640	COG1609	Transcriptional regulator
Axylo_RS00650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_RS00665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Axylo_RS00675	COG0583	DNA-binding transcription factor activity
Axylo_RS00695	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Axylo_RS00700	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS00705	COG0513	Belongs to the DEAD box helicase family
Axylo_RS00710	COG5339	Protein conserved in bacteria
Axylo_RS00715	COG5339	Protein conserved in bacteria
Axylo_RS00720	COG1228	amidohydrolase
Axylo_RS00730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS00735	COG0601	transmembrane transport
Axylo_RS00740	COG0747	negative chemotaxis
Axylo_RS00755	COG2207	Transcriptional regulator
Axylo_RS00755	COG3708	Transcriptional regulator
Axylo_RS00765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Axylo_RS00800	COG0463	Glycosyl transferase, family 2
Axylo_RS00810	COG3959	Transketolase, thiamine diphosphate binding domain
Axylo_RS00845	COG2969	positive regulation of protein catabolic process
Axylo_RS00850	COG0625	glutathione transferase activity
Axylo_RS00855	COG2857	Cytochrome c1
Axylo_RS00860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Axylo_RS00865	COG0723	plastoquinol--plastocyanin reductase activity
Axylo_RS00870	COG1970	mechanosensitive ion channel activity
Axylo_RS00875	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Axylo_RS00895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Axylo_RS00900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Axylo_RS00905	COG0537	adenosine 5'-monophosphoramidase activity
Axylo_RS00910	COG0140	phosphoribosyl-ATP diphosphatase activity
Axylo_RS00915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Axylo_RS00920	COG0107	imidazoleglycerol-phosphate synthase activity
Axylo_RS00925	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Axylo_RS00930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Axylo_RS00935	COG0131	Imidazoleglycerol-phosphate dehydratase
Axylo_RS00940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Axylo_RS00945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Axylo_RS00950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Axylo_RS00955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Axylo_RS00965	COG0842	Transport permease protein
Axylo_RS00970	COG1131	(ABC) transporter
Axylo_RS00980	COG2853	Lipoprotein
Axylo_RS00985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Axylo_RS00990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Axylo_RS00995	COG1127	ABC transporter
Axylo_RS01010	COG0477	Major facilitator Superfamily
Axylo_RS01025	COG0583	DNA-binding transcription factor activity
Axylo_RS01030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Axylo_RS01035	COG0511	ligase activity, forming carbon-carbon bonds
Axylo_RS01050	COG1984	allophanate hydrolase subunit 2
Axylo_RS01075	COG0070	glutamate synthase
Axylo_RS01075	COG0069	glutamate synthase activity
Axylo_RS01075	COG0067	glutamate synthase
Axylo_RS01100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Axylo_RS01120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Axylo_RS01135	COG1845	cytochrome c oxidase, subunit III
Axylo_RS01155	COG1612	heme a metabolic process
Axylo_RS01165	COG1999	signal sequence binding
Axylo_RS01185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Axylo_RS01190	COG2814	Major facilitator Superfamily
Axylo_RS01215	COG3328	transposase activity
Axylo_RS01225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Axylo_RS01235	COG2801	Transposase and inactivated derivatives
Axylo_RS01250	COG0456	acetyltransferase
Axylo_RS01290	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Axylo_RS01315	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Axylo_RS01320	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Axylo_RS01325	COG2814	Major facilitator Superfamily
Axylo_RS01330	COG0583	DNA-binding transcription factor activity
Axylo_RS01335	COG2423	ornithine cyclodeaminase activity
Axylo_RS01340	COG5001	Diguanylate cyclase
Axylo_RS01345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Axylo_RS01350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Axylo_RS01360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Axylo_RS01370	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Axylo_RS01375	COG0463	Glycosyl transferase, family 2
Axylo_RS01415	COG0737	Belongs to the 5'-nucleotidase family
Axylo_RS01440	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Axylo_RS01445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Axylo_RS01465	COG0840	transmembrane signaling receptor activity
Axylo_RS01470	COG2814	Major facilitator Superfamily
Axylo_RS01485	COG3188	usher protein
Axylo_RS01545	COG1802	Transcriptional regulator
Axylo_RS01555	COG3069	C4-dicarboxylate transmembrane transporter activity
Axylo_RS01560	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_RS01575	COG0589	response to stress
Axylo_RS01580	COG0431	NADPH-dependent FMN reductase
Axylo_RS01585	COG3585	molybdate ion transport
Axylo_RS01605	COG1607	acyl-coa hydrolase
Axylo_RS01615	COG0243	molybdopterin cofactor binding
Axylo_RS01615	COG3383	formate dehydrogenase (NAD+) activity
Axylo_RS01620	COG0243	molybdopterin cofactor binding
Axylo_RS01620	COG3383	formate dehydrogenase (NAD+) activity
Axylo_RS01625	COG0437	4 iron, 4 sulfur cluster binding
Axylo_RS01630	COG2864	formate dehydrogenase
Axylo_RS01645	COG3276	selenocysteine insertion sequence binding
Axylo_RS01655	COG1215	transferase activity, transferring glycosyl groups
Axylo_RS01660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_RS01665	COG1305	Transglutaminase-like
Axylo_RS01670	COG0709	Synthesizes selenophosphate from selenide and ATP
Axylo_RS01700	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_RS01705	COG3284	Transcriptional regulator
Axylo_RS01710	COG0134	indole-3-glycerol-phosphate synthase activity
Axylo_RS01715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Axylo_RS01720	COG0512	Glutamine amidotransferase of anthranilate synthase
Axylo_RS01730	COG0546	phosphoglycolate phosphatase activity
Axylo_RS01735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Axylo_RS01740	COG2967	ApaG domain
Axylo_RS01750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Axylo_RS01760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_RS01765	COG0037	tRNA processing
Axylo_RS01780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_RS01785	COG0583	DNA-binding transcription factor activity
Axylo_RS01790	COG3473	Maleate cis-trans isomerase
Axylo_RS01795	COG0583	DNA-binding transcription factor activity
Axylo_RS01810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Axylo_RS01820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Axylo_RS01825	COG1024	Enoyl-CoA hydratase
Axylo_RS01840	COG0356	it plays a direct role in the translocation of protons across the membrane
Axylo_RS01855	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Axylo_RS01860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Axylo_RS01865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Axylo_RS01875	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Axylo_RS01885	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Axylo_RS01890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Axylo_RS01895	COG0210	DNA helicase
Axylo_RS01910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Axylo_RS01915	COG4221	oxidoreductase activity
Axylo_RS01925	COG2171	N-acyltransferase activity
Axylo_RS01935	COG2195	Cleaves the N-terminal amino acid of tripeptides
Axylo_RS01945	COG4608	Belongs to the ABC transporter superfamily
Axylo_RS01950	COG0444	Belongs to the ABC transporter superfamily
Axylo_RS01960	COG0601	transmembrane transport
Axylo_RS01965	COG0747	negative chemotaxis
Axylo_RS01970	COG2988	succinylglutamate desuccinylase activity
Axylo_RS01980	COG0583	DNA-binding transcription factor activity
Axylo_RS01985	COG0747	negative chemotaxis
Axylo_RS01995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Axylo_RS02000	COG1024	Enoyl-CoA hydratase
Axylo_RS02005	COG1024	Enoyl-CoA hydratase
Axylo_RS02015	COG1309	transcriptional regulator
Axylo_RS02030	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_RS02055	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS02060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS02075	COG0179	Fumarylacetoacetate (FAA) hydrolase
Axylo_RS02095	COG1129	ABC transporter
Axylo_RS02110	COG1802	Transcriptional regulator
Axylo_RS02120	COG0583	DNA-binding transcription factor activity
Axylo_RS02130	COG2988	succinylglutamate desuccinylase activity
Axylo_RS02140	COG2918	glutathione biosynthetic process
Axylo_RS02170	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Axylo_RS02175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_RS02185	COG2721	sulfolactate sulfo-lyase activity
Axylo_RS02190	COG2721	sulfolactate sulfo-lyase activity
Axylo_RS02195	COG2188	Transcriptional regulator
Axylo_RS02200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_RS02205	COG2813	Specifically methylates the guanine in position
Axylo_RS02205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_RS02210	COG2223	nitrite transmembrane transporter activity
Axylo_RS02220	COG2860	membrane
Axylo_RS02225	COG1802	Transcriptional regulator
Axylo_RS02235	COG1984	allophanate hydrolase subunit 2
Axylo_RS02240	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Axylo_RS02255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_RS02270	COG2132	Multicopper oxidase
Axylo_RS02295	COG0745	RESPONSE REGULATOR receiver
Axylo_RS02300	COG2226	methyltransferase
Axylo_RS02315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Axylo_RS02325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Axylo_RS02335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Axylo_RS02340	COG0351	phosphomethylpyrimidine kinase
Axylo_RS02345	COG2022	thiamine diphosphate biosynthetic process
Axylo_RS02350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Axylo_RS02355	COG4771	TonB-dependent receptor
Axylo_RS02365	COG2186	Transcriptional regulator
Axylo_RS02380	COG1063	alcohol dehydrogenase
Axylo_RS02390	COG0765	amino acid transport
Axylo_RS02395	COG1126	abc transporter atp-binding protein
Axylo_RS02400	COG4948	Mandelate Racemase Muconate Lactonizing
Axylo_RS02405	COG0246	Mannitol dehydrogenase
Axylo_RS02420	COG1194	a g-specific adenine glycosylase
Axylo_RS02435	COG2177	Part of the ABC transporter FtsEX involved in
Axylo_RS02440	COG2884	Cell division ATP-binding protein ftsE
Axylo_RS02445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS02450	COG4597	amino acid ABC transporter
Axylo_RS02455	COG0765	amino acid transport
Axylo_RS02460	COG1126	abc transporter atp-binding protein
Axylo_RS02485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Axylo_RS02490	COG2081	HI0933 family
Axylo_RS02500	COG0077	Prephenate dehydratase
Axylo_RS02500	COG1605	Chorismate mutase
Axylo_RS02535	COG0477	Major facilitator Superfamily
Axylo_RS02545	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Axylo_RS02550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Axylo_RS02570	COG0237	dephospho-CoA kinase activity
Axylo_RS02575	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Axylo_RS02605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS02610	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_RS02625	COG3833	ABC-type maltose transport systems, permease component
Axylo_RS02630	COG1175	transmembrane transport
Axylo_RS02635	COG3842	ATPase activity
Axylo_RS02655	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Axylo_RS02690	COG0410	ABC transporter
Axylo_RS02725	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS02730	COG1024	Enoyl-CoA hydratase
Axylo_RS02770	COG4638	Rieske (2fe-2S)
Axylo_RS02775	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Axylo_RS02780	COG1335	isochorismatase
Axylo_RS02785	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS02795	COG0741	lytic transglycosylase activity
Axylo_RS02800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Axylo_RS02805	COG0352	thiamine-phosphate diphosphorylase activity
Axylo_RS02820	COG1678	Uncharacterized ACR, COG1678
Axylo_RS02825	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Axylo_RS02845	COG1126	abc transporter atp-binding protein
Axylo_RS02850	COG0765	amino acid transport
Axylo_RS02860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS02865	COG0436	Aminotransferase
Axylo_RS02870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Axylo_RS02880	COG3328	transposase activity
Axylo_RS02885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Axylo_RS02895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Axylo_RS02900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Axylo_RS02910	COG3842	ATPase activity
Axylo_RS02915	COG1175	transmembrane transport
Axylo_RS02935	COG0557	exoribonuclease II activity
Axylo_RS02940	COG3150	esterase
Axylo_RS02945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Axylo_RS02950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_RS02955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Axylo_RS02960	COG0511	ligase activity, forming carbon-carbon bonds
Axylo_RS02965	COG0439	Biotin carboxylase
Axylo_RS02970	COG2264	protein methyltransferase activity
Axylo_RS02980	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Axylo_RS02980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Axylo_RS03005	COG1696	Membrane protein involved in D-alanine export
Axylo_RS03010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Axylo_RS03040	COG1522	sequence-specific DNA binding
Axylo_RS03045	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS03055	COG0583	DNA-binding transcription factor activity
Axylo_RS03070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Axylo_RS03075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Axylo_RS03075	COG1042	CoA-binding domain protein
Axylo_RS03075	COG0045	succinate-CoA ligase (ADP-forming) activity
Axylo_RS03080	COG1335	isochorismatase
Axylo_RS03085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_RS03090	COG1116	anion transmembrane transporter activity
Axylo_RS03105	COG3028	Belongs to the UPF0307 family
Axylo_RS03110	COG0312	modulator of DNA gyrase
Axylo_RS03115	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Axylo_RS03125	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS03130	COG4177	L-phenylalanine transmembrane transporter activity
Axylo_RS03145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Axylo_RS03150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Axylo_RS03155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Axylo_RS03165	COG0316	Belongs to the HesB IscA family
Axylo_RS03180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Axylo_RS03190	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS03195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Axylo_RS03200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Axylo_RS03215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Axylo_RS03215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Axylo_RS03230	COG2766	serine protein kinase
Axylo_RS03235	COG2718	Belongs to the UPF0229 family
Axylo_RS03240	COG2719	SpoVR family
Axylo_RS03250	COG0583	DNA-binding transcription factor activity
Axylo_RS03255	COG1942	4-Oxalocrotonate Tautomerase
Axylo_RS03265	COG0456	acetyltransferase
Axylo_RS03275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Axylo_RS03330	COG4789	Type iii secretion
Axylo_RS03405	COG4669	(LipO)protein
Axylo_RS03435	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Axylo_RS03440	COG4790	Type iii secretion
Axylo_RS03445	COG4794	Type iii secretion
Axylo_RS03450	COG4791	protein targeting
Axylo_RS03455	COG4792	protein secretion
Axylo_RS03485	COG2208	phosphoserine phosphatase activity
Axylo_RS03485	COG2770	Histidine kinase
Axylo_RS03495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Axylo_RS03500	COG2172	sigma factor antagonist activity
Axylo_RS03505	COG1366	Belongs to the anti-sigma-factor antagonist family
Axylo_RS03545	COG0741	lytic transglycosylase activity
Axylo_RS03545	COG1388	LysM domain
Axylo_RS03550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Axylo_RS03555	COG2226	methyltransferase
Axylo_RS03560	COG0328	RNA-DNA hybrid ribonuclease activity
Axylo_RS03570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_RS03590	COG1671	Belongs to the UPF0178 family
Axylo_RS03605	COG0786	glutamate:sodium symporter activity
Axylo_RS03615	COG0463	Glycosyl transferase, family 2
Axylo_RS03620	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Axylo_RS03635	COG0583	DNA-binding transcription factor activity
Axylo_RS03655	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS03675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_RS03685	COG0583	DNA-binding transcription factor activity
Axylo_RS03690	COG1380	Effector of murein hydrolase LrgA
Axylo_RS03705	COG0697	spore germination
Axylo_RS03710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS03725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Axylo_RS03735	COG1522	sequence-specific DNA binding
Axylo_RS03750	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Axylo_RS03755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_RS03770	COG0823	Involved in the tonB-independent uptake of proteins
Axylo_RS03780	COG0848	biopolymer transport protein
Axylo_RS03785	COG0811	peptide transport
Axylo_RS03790	COG0824	Thioesterase
Axylo_RS03795	COG0442	prolyl-tRNA aminoacylation
Axylo_RS03825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_RS03840	COG2084	Dehydrogenase
Axylo_RS03845	COG0405	Gamma-glutamyltransferase
Axylo_RS03880	COG0129	dihydroxy-acid dehydratase activity
Axylo_RS03885	COG4654	Cytochrome c, class I
Axylo_RS03890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Axylo_RS03900	COG1522	sequence-specific DNA binding
Axylo_RS03940	COG1473	amidohydrolase
Axylo_RS03945	COG0418	dihydroorotase activity
Axylo_RS03950	COG0488	(ABC) transporter
Axylo_RS03955	COG2001	Belongs to the MraZ family
Axylo_RS03960	COG0275	rRNA processing
Axylo_RS03965	COG3116	cell division
Axylo_RS03975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Axylo_RS03980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Axylo_RS03985	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Axylo_RS03995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Axylo_RS04000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Axylo_RS04005	COG1181	Belongs to the D-alanine--D-alanine ligase family
Axylo_RS04010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Axylo_RS04020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Axylo_RS04025	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Axylo_RS04035	COG0739	heme binding
Axylo_RS04040	COG0653	protein targeting
Axylo_RS04055	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS04060	COG0028	Belongs to the TPP enzyme family
Axylo_RS04070	COG0300	oxidoreductase activity
Axylo_RS04075	COG1522	sequence-specific DNA binding
Axylo_RS04090	COG2239	Acts as a magnesium transporter
Axylo_RS04100	COG2855	membrane
Axylo_RS04105	COG0583	DNA-binding transcription factor activity
Axylo_RS04110	COG1473	amidohydrolase
Axylo_RS04115	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_RS04120	COG0483	inositol monophosphate 1-phosphatase activity
Axylo_RS04125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS04125	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Axylo_RS04130	COG1501	Belongs to the glycosyl hydrolase 31 family
Axylo_RS04135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Axylo_RS04140	COG2011	ABC-type metal ion transport system permease component
Axylo_RS04195	COG0840	transmembrane signaling receptor activity
Axylo_RS04200	COG0583	DNA-binding transcription factor activity
Axylo_RS04210	COG0735	belongs to the Fur family
Axylo_RS04230	COG2818	Glycosylase
Axylo_RS04235	COG1368	sulfuric ester hydrolase activity
Axylo_RS04240	COG2982	Protein involved in outer membrane biogenesis
Axylo_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS04285	COG2154	pterin-4-alpha-carbinolamine dehydratase
Axylo_RS04310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Axylo_RS04325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_RS04330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Axylo_RS04335	COG1929	Belongs to the glycerate kinase type-1 family
Axylo_RS04340	COG0469	pyruvate kinase activity
Axylo_RS04345	COG0700	Nucleoside recognition
Axylo_RS04350	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS04355	COG0242	peptide deformylase activity
Axylo_RS04365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Axylo_RS04375	COG0204	Acyl-transferase
Axylo_RS04380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Axylo_RS04385	COG0751	glycine-tRNA ligase activity
Axylo_RS04390	COG0752	glycyl-tRNA synthetase alpha subunit
Axylo_RS04395	COG1024	Enoyl-CoA hydratase
Axylo_RS04410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS04415	COG2030	dehydratase
Axylo_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS04440	COG2070	2-Nitropropane dioxygenase
Axylo_RS04450	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_RS04455	COG0183	Belongs to the thiolase family
Axylo_RS04465	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS04475	COG1024	Enoyl-CoA hydratase
Axylo_RS04485	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Axylo_RS04495	COG2301	Belongs to the HpcH HpaI aldolase family
Axylo_RS04500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Axylo_RS04510	COG0617	tRNA 3'-terminal CCA addition
Axylo_RS04525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Axylo_RS04535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Axylo_RS04540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Axylo_RS04545	COG0586	Pfam SNARE associated Golgi protein
Axylo_RS04555	COG0860	N-Acetylmuramoyl-L-alanine amidase
Axylo_RS04560	COG0114	fumarate hydratase activity
Axylo_RS04570	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS04585	COG0531	amino acid
Axylo_RS04590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS04600	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS04605	COG0583	DNA-binding transcription factor activity
Axylo_RS04615	COG0579	oxidoreductase
Axylo_RS04625	COG0259	pyridoxamine-phosphate oxidase activity
Axylo_RS04640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_RS04645	COG1136	(ABC) transporter
Axylo_RS04645	COG0577	efflux transmembrane transporter activity
Axylo_RS04650	COG1538	Outer membrane efflux protein
Axylo_RS04655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Axylo_RS04690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Axylo_RS04700	COG0800	Aldolase
Axylo_RS04715	COG1216	Glycosyl transferase, family 2
Axylo_RS04715	COG0463	Glycosyl transferase, family 2
Axylo_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS04745	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Axylo_RS04765	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Axylo_RS04770	COG4638	Rieske (2fe-2S)
Axylo_RS04795	COG0747	negative chemotaxis
Axylo_RS04800	COG0601	transmembrane transport
Axylo_RS04805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS04810	COG0444	Belongs to the ABC transporter superfamily
Axylo_RS04815	COG4608	Belongs to the ABC transporter superfamily
Axylo_RS04835	COG2746	aminoglycoside 3-N-acetyltransferase activity
Axylo_RS04840	COG0488	(ABC) transporter
Axylo_RS04860	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Axylo_RS04865	COG2894	cell division
Axylo_RS04870	COG0850	regulation of cytokinetic process
Axylo_RS04875	COG1414	Transcriptional regulator
Axylo_RS04880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_RS04885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS04895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Axylo_RS04905	COG1294	oxidase, subunit
Axylo_RS04910	COG0514	ATP-dependent DNA helicase (RecQ)
Axylo_RS04930	COG2255	four-way junction helicase activity
Axylo_RS04940	COG1090	epimerase
Axylo_RS04945	COG0632	four-way junction helicase activity
Axylo_RS04970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Axylo_RS04980	COG0006	proline dipeptidase activity
Axylo_RS04995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Axylo_RS05000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS05015	COG4783	chaperone-mediated protein folding
Axylo_RS05055	COG2814	Major facilitator Superfamily
Axylo_RS05070	COG0513	Belongs to the DEAD box helicase family
Axylo_RS05085	COG1058	Belongs to the CinA family
Axylo_RS05085	COG1546	Belongs to the CinA family
Axylo_RS05090	COG1414	Transcriptional regulator
Axylo_RS05105	COG0167	dihydroorotate dehydrogenase activity
Axylo_RS05110	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Axylo_RS05115	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Axylo_RS05125	COG0583	DNA-binding transcription factor activity
Axylo_RS05180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Axylo_RS05205	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Axylo_RS05210	COG0735	belongs to the Fur family
Axylo_RS05215	COG0497	DNA recombination
Axylo_RS05225	COG1420	regulation of RNA biosynthetic process
Axylo_RS05230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Axylo_RS05240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Axylo_RS05250	COG0443	Heat shock 70 kDa protein
Axylo_RS05255	COG0484	heat shock protein binding
Axylo_RS05270	COG1595	DNA-templated transcription, initiation
Axylo_RS05280	COG0612	Peptidase, M16
Axylo_RS05305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Axylo_RS05345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_RS05360	COG0745	RESPONSE REGULATOR receiver
Axylo_RS05365	COG2205	protein histidine kinase activity
Axylo_RS05370	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Axylo_RS05375	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Axylo_RS05380	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Axylo_RS05395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Axylo_RS05405	COG1193	negative regulation of DNA recombination
Axylo_RS05410	COG0492	ferredoxin-NADP+ reductase activity
Axylo_RS05415	COG1674	ftsk spoiiie
Axylo_RS05420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Axylo_RS05425	COG0251	oxidation-reduction process
Axylo_RS05430	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_RS05435	COG0517	IMP dehydrogenase activity
Axylo_RS05435	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Axylo_RS05455	COG0601	transmembrane transport
Axylo_RS05470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Axylo_RS05475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Axylo_RS05480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Axylo_RS05515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_RS05535	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS05540	COG3022	response to hydroperoxide
Axylo_RS05545	COG1289	transmembrane transporter activity
Axylo_RS05550	COG0028	Belongs to the TPP enzyme family
Axylo_RS05555	COG0440	acetolactate synthase activity
Axylo_RS05560	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Axylo_RS05565	COG1183	phosphatidylcholine synthase activity
Axylo_RS05575	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Axylo_RS05580	COG1185	polyribonucleotide nucleotidyltransferase activity
Axylo_RS05590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Axylo_RS05605	COG4774	siderophore transport
Axylo_RS05645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS05655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_RS05675	COG0149	triose-phosphate isomerase activity
Axylo_RS05680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Axylo_RS05695	COG0582	viral genome integration into host DNA
Axylo_RS05780	COG1595	DNA-templated transcription, initiation
Axylo_RS05785	COG3712	iron ion homeostasis
Axylo_RS05810	COG1595	DNA-templated transcription, initiation
Axylo_RS05840	COG4191	Histidine kinase
Axylo_RS05845	COG4566	intracellular signal transduction
Axylo_RS05855	COG0642	Histidine kinase
Axylo_RS05870	COG2851	Citrate transporter
Axylo_RS05875	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS05895	COG1278	Cold shock
Axylo_RS05910	COG3813	Protein conserved in bacteria
Axylo_RS05915	COG2354	Protein conserved in bacteria
Axylo_RS05930	COG4772	TonB-dependent receptor
Axylo_RS05935	COG1522	sequence-specific DNA binding
Axylo_RS05965	COG0747	negative chemotaxis
Axylo_RS05985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_RS06000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Axylo_RS06005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_RS06010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_RS06030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_RS06035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_RS06040	COG1309	transcriptional regulator
Axylo_RS06045	COG0583	DNA-binding transcription factor activity
Axylo_RS06065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Axylo_RS06090	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS06095	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Axylo_RS06100	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Axylo_RS06105	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Axylo_RS06110	COG0649	NAD binding
Axylo_RS06115	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Axylo_RS06125	COG1034	ATP synthesis coupled electron transport
Axylo_RS06130	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Axylo_RS06135	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Axylo_RS06145	COG0713	ATP synthesis coupled electron transport
Axylo_RS06160	COG1007	ATP synthesis coupled electron transport
Axylo_RS06170	COG4774	siderophore transport
Axylo_RS06175	COG0560	Phosphoserine phosphatase
Axylo_RS06180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Axylo_RS06185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Axylo_RS06190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Axylo_RS06200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Axylo_RS06205	COG0450	alkyl hydroperoxide reductase
Axylo_RS06220	COG1214	PFAM Peptidase M22, glycoprotease
Axylo_RS06225	COG1573	uracil-dna glycosylase
Axylo_RS06230	COG0477	Major facilitator Superfamily
Axylo_RS06235	COG1196	nuclear chromosome segregation
Axylo_RS06245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Axylo_RS06250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_RS06260	COG2917	probably involved in intracellular septation
Axylo_RS06265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Axylo_RS06270	COG1122	ATPase activity
Axylo_RS06275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Axylo_RS06280	COG1268	BioY protein
Axylo_RS06315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Axylo_RS06350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Axylo_RS06355	COG2878	Part of a membrane complex involved in electron transport
Axylo_RS06370	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Axylo_RS06375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Axylo_RS06380	COG0251	oxidation-reduction process
Axylo_RS06390	COG3228	Belongs to the MtfA family
Axylo_RS06395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Axylo_RS06405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Axylo_RS06415	COG0159	tryptophan synthase activity
Axylo_RS06420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Axylo_RS06425	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Axylo_RS06430	COG1530	ribonuclease E activity
Axylo_RS06435	COG0564	pseudouridine synthase activity
Axylo_RS06440	COG0546	phosphoglycolate phosphatase activity
Axylo_RS06445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Axylo_RS06450	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Axylo_RS06465	COG0424	maF-like protein
Axylo_RS06475	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Axylo_RS06485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Axylo_RS06490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Axylo_RS06500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Axylo_RS06505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Axylo_RS06530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Axylo_RS06540	COG0681	Belongs to the peptidase S26 family
Axylo_RS06545	COG0571	ribonuclease III activity
Axylo_RS06550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Axylo_RS06555	COG1381	Involved in DNA repair and RecF pathway recombination
Axylo_RS06565	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Axylo_RS06575	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS06585	COG0667	Aldo Keto reductase
Axylo_RS06605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Axylo_RS06630	COG0583	DNA-binding transcription factor activity
Axylo_RS06640	COG0791	NLP P60 protein
Axylo_RS06645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Axylo_RS06650	COG3193	protein, possibly involved in utilization of glycolate and propanediol
Axylo_RS06660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Axylo_RS06665	COG0697	spore germination
Axylo_RS06670	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Axylo_RS06710	COG2153	protein acetylation
Axylo_RS06720	COG1446	asparaginase
Axylo_RS06725	COG4172	Belongs to the ABC transporter superfamily
Axylo_RS06730	COG0747	negative chemotaxis
Axylo_RS06740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS06765	COG0504	CTP synthase activity
Axylo_RS06775	COG0148	phosphopyruvate hydratase activity
Axylo_RS06790	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Axylo_RS06800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Axylo_RS06835	COG1981	membrane
Axylo_RS06855	COG0039	L-malate dehydrogenase activity
Axylo_RS06860	COG2188	Transcriptional regulator
Axylo_RS06865	COG2009	succinate dehydrogenase
Axylo_RS06870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Axylo_RS06875	COG1053	succinate dehydrogenase
Axylo_RS06880	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Axylo_RS06885	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Axylo_RS06890	COG0372	Belongs to the citrate synthase family
Axylo_RS06905	COG0281	malic enzyme
Axylo_RS06905	COG0280	phosphate acetyltransferase
Axylo_RS06915	COG1297	OPT oligopeptide transporter protein
Axylo_RS06920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Axylo_RS06935	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Axylo_RS06940	COG1522	sequence-specific DNA binding
Axylo_RS06945	COG0567	Dehydrogenase, E1 component
Axylo_RS06950	COG0508	dehydrogenase complex catalyzes the overall conversion of
Axylo_RS06955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Axylo_RS06960	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Axylo_RS06965	COG1595	DNA-templated transcription, initiation
Axylo_RS06970	COG3712	iron ion homeostasis
Axylo_RS06975	COG4774	siderophore transport
Axylo_RS07010	COG2183	response to ionizing radiation
Axylo_RS07015	COG1199	ATP-dependent helicase activity
Axylo_RS07025	COG0564	pseudouridine synthase activity
Axylo_RS07030	COG1496	oxidoreductase activity
Axylo_RS07035	COG3243	poly(R)-hydroxyalkanoic acid synthase
Axylo_RS07040	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS07045	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Axylo_RS07070	COG2831	hemolysin activation secretion protein
Axylo_RS07085	COG3328	transposase activity
Axylo_RS07095	COG2823	Periplasmic or secreted lipoprotein
Axylo_RS07105	COG3237	CsbD-like
Axylo_RS07110	COG0189	ligase activity
Axylo_RS07110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Axylo_RS07115	COG0189	ligase activity
Axylo_RS07115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Axylo_RS07120	COG1132	(ABC) transporter
Axylo_RS07135	COG2833	Protein of unknown function (DUF455)
Axylo_RS07140	COG2258	MOSC domain
Axylo_RS07145	COG2951	lytic endotransglycosylase activity
Axylo_RS07160	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS07170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Axylo_RS07180	COG1696	Membrane protein involved in D-alanine export
Axylo_RS07200	COG1215	transferase activity, transferring glycosyl groups
Axylo_RS07210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Axylo_RS07220	COG0582	viral genome integration into host DNA
Axylo_RS07270	COG2755	lipolytic protein G-D-S-L family
Axylo_RS07270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Axylo_RS07310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Axylo_RS07325	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Axylo_RS07335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Axylo_RS07345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Axylo_RS07350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Axylo_RS07370	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Axylo_RS07375	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Axylo_RS07380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_RS07410	COG2951	lytic endotransglycosylase activity
Axylo_RS07415	COG0123	including yeast histone deacetylase and acetoin utilization protein
Axylo_RS07440	COG2985	domain, Protein
Axylo_RS07445	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS07450	COG0450	alkyl hydroperoxide reductase
Axylo_RS07460	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Axylo_RS07465	COG4208	sulfate ABC transporter
Axylo_RS07475	COG0175	sulfate reduction
Axylo_RS07505	COG0335	large ribosomal subunit rRNA binding
Axylo_RS07515	COG1162	GTPase activity
Axylo_RS07520	COG0501	Belongs to the peptidase M48B family
Axylo_RS07525	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Axylo_RS07530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Axylo_RS07535	COG3327	negative regulation of DNA-templated transcription, initiation
Axylo_RS07540	COG3396	Phenylacetate-CoA oxygenase
Axylo_RS07545	COG3460	Phenylacetate-CoA oxygenase
Axylo_RS07550	COG3396	Phenylacetate-CoA oxygenase
Axylo_RS07555	COG2151	metal-sulfur cluster biosynthetic enzyme
Axylo_RS07560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Axylo_RS07565	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_RS07570	COG1024	Enoyl-CoA hydratase
Axylo_RS07575	COG2050	protein possibly involved in aromatic compounds catabolism
Axylo_RS07585	COG0534	Mate efflux family protein
Axylo_RS07600	COG3483	tryptophan 2,3-dioxygenase activity
Axylo_RS07605	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Axylo_RS07610	COG2003	Belongs to the UPF0758 family
Axylo_RS07620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Axylo_RS07625	COG0625	glutathione transferase activity
Axylo_RS07630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Axylo_RS07655	COG0523	cobalamin synthesis protein
Axylo_RS07660	COG0523	cobalamin synthesis protein
Axylo_RS07665	COG0583	DNA-binding transcription factor activity
Axylo_RS07675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Axylo_RS07680	COG1187	pseudouridine synthase activity
Axylo_RS07685	COG0779	Required for maturation of 30S ribosomal subunits
Axylo_RS07690	COG0195	Participates in both transcription termination and antitermination
Axylo_RS07690	COG2251	uridine kinase activity
Axylo_RS07695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Axylo_RS07700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Axylo_RS07705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Axylo_RS07710	COG1217	gtp-binding protein TYPA
Axylo_RS07720	COG0583	DNA-binding transcription factor activity
Axylo_RS07730	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS07735	COG1473	amidohydrolase
Axylo_RS07740	COG1611	Belongs to the LOG family
Axylo_RS07745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Axylo_RS07745	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Axylo_RS07755	COG0412	Dienelactone hydrolase
Axylo_RS07760	COG1283	sodium-dependent phosphate transmembrane transporter activity
Axylo_RS07765	COG1760	l-serine dehydratase
Axylo_RS07770	COG0501	Belongs to the peptidase M48B family
Axylo_RS07790	COG0583	DNA-binding transcription factor activity
Axylo_RS07795	COG3842	ATPase activity
Axylo_RS07805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Axylo_RS07810	COG1840	ABC-type Fe3 transport system, periplasmic component
Axylo_RS07830	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS07840	COG1722	exodeoxyribonuclease VII activity
Axylo_RS07845	COG0142	geranyltranstransferase activity
Axylo_RS07855	COG1469	GTP cyclohydrolase I activity
Axylo_RS07860	COG3739	integral membrane protein
Axylo_RS07865	COG0360	Binds together with S18 to 16S ribosomal RNA
Axylo_RS07870	COG2965	DNA replication, synthesis of RNA primer
Axylo_RS07875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Axylo_RS07880	COG0359	binds to the 23S rRNA
Axylo_RS07890	COG0305	Participates in initiation and elongation during chromosome replication
Axylo_RS07900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Axylo_RS07935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS07955	COG0493	'glutamate synthase
Axylo_RS07985	COG0540	Belongs to the ATCase OTCase family
Axylo_RS08020	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Axylo_RS08025	COG2137	regulation of response to DNA damage stimulus
Axylo_RS08040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Axylo_RS08050	COG0045	succinate-CoA ligase (ADP-forming) activity
Axylo_RS08055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Axylo_RS08060	COG0861	Integral membrane protein TerC family
Axylo_RS08065	COG0861	Integral membrane protein TerC family
Axylo_RS08075	COG0181	hydroxymethylbilane synthase activity
Axylo_RS08105	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS08120	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS08135	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS08160	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Axylo_RS08170	COG0436	Aminotransferase
Axylo_RS08190	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Axylo_RS08195	COG0308	aminopeptidase N
Axylo_RS08210	COG0312	modulator of DNA gyrase
Axylo_RS08215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Axylo_RS08220	COG0277	FAD linked oxidase domain protein
Axylo_RS08225	COG0308	aminopeptidase N
Axylo_RS08240	COG0312	modulator of DNA gyrase
Axylo_RS08245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Axylo_RS08250	COG0277	FAD linked oxidase domain protein
Axylo_RS08255	COG0308	aminopeptidase N
Axylo_RS08270	COG0312	modulator of DNA gyrase
Axylo_RS08275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Axylo_RS08280	COG0277	FAD linked oxidase domain protein
Axylo_RS08285	COG0277	FAD linked oxidase domain protein
Axylo_RS08290	COG0277	FAD linked oxidase domain protein
Axylo_RS08295	COG0247	lactate metabolic process
Axylo_RS08325	COG0583	DNA-binding transcription factor activity
Axylo_RS08330	COG0482	sulfurtransferase activity
Axylo_RS08335	COG0730	response to heat
Axylo_RS08340	COG0625	glutathione transferase activity
Axylo_RS08350	COG3909	cytochrome
Axylo_RS08355	COG2801	Transposase and inactivated derivatives
Axylo_RS08390	COG0628	permease
Axylo_RS08400	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
Axylo_RS08420	COG2801	Transposase and inactivated derivatives
Axylo_RS08530	COG0697	spore germination
Axylo_RS08565	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Axylo_RS08575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Axylo_RS08580	COG0069	glutamate synthase activity
Axylo_RS08585	COG2391	methyltransferase activity
Axylo_RS08590	COG0679	Auxin Efflux Carrier
Axylo_RS08620	COG0557	exoribonuclease II activity
Axylo_RS08625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Axylo_RS08635	COG3128	pkhd-type hydroxylase
Axylo_RS08640	COG0776	regulation of translation
Axylo_RS08670	COG0642	Histidine kinase
Axylo_RS08675	COG3158	transport of potassium into the cell
Axylo_RS08680	COG0137	argininosuccinate synthase activity
Axylo_RS08685	COG1538	Outer membrane efflux protein
Axylo_RS08695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_RS08705	COG5002	protein histidine kinase activity
Axylo_RS08710	COG0583	DNA-binding transcription factor activity
Axylo_RS08715	COG3618	amidohydrolase
Axylo_RS08735	COG2945	thiolester hydrolase activity
Axylo_RS08735	COG0596	Alpha beta hydrolase
Axylo_RS08740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Axylo_RS08745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Axylo_RS08765	COG0747	negative chemotaxis
Axylo_RS08770	COG0601	transmembrane transport
Axylo_RS08775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS08785	COG0402	S-adenosylhomocysteine deaminase activity
Axylo_RS08800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Axylo_RS08800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Axylo_RS08810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_RS08815	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Axylo_RS08825	COG3642	lipopolysaccharide core region biosynthetic process
Axylo_RS08835	COG3842	ATPase activity
Axylo_RS08840	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_RS08845	COG1177	transmembrane transport
Axylo_RS08875	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS08885	COG0704	Plays a role in the regulation of phosphate uptake
Axylo_RS08895	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Axylo_RS08900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Axylo_RS08900	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Axylo_RS08905	COG1643	Atp-dependent helicase
Axylo_RS08910	COG0395	ABC-type sugar transport system, permease component
Axylo_RS08915	COG1116	anion transmembrane transporter activity
Axylo_RS08930	COG0438	transferase activity, transferring glycosyl groups
Axylo_RS08935	COG0726	polysaccharide deacetylase
Axylo_RS08950	COG0726	polysaccharide deacetylase
Axylo_RS08975	COG1132	(ABC) transporter
Axylo_RS08980	COG0475	glutathione-regulated potassium exporter activity
Axylo_RS08980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Axylo_RS08995	COG2203	Gaf domain
Axylo_RS08995	COG5001	Diguanylate cyclase
Axylo_RS08995	COG3706	GGDEF domain
Axylo_RS08995	COG4251	negative regulation of phosphorylation
Axylo_RS09035	COG1530	ribonuclease E activity
Axylo_RS09080	COG0583	DNA-binding transcription factor activity
Axylo_RS09095	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_RS09105	COG0477	Major facilitator Superfamily
Axylo_RS09115	COG0154	amidase activity
Axylo_RS09135	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Axylo_RS09150	COG0495	leucyl-tRNA aminoacylation
Axylo_RS09155	COG2814	Major facilitator Superfamily
Axylo_RS09160	COG1846	Transcriptional regulator
Axylo_RS09170	COG1686	Belongs to the peptidase S11 family
Axylo_RS09205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Axylo_RS09210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Axylo_RS09215	COG2814	Major facilitator Superfamily
Axylo_RS09220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Axylo_RS09230	COG4176	ABC-type proline glycine betaine transport system permease component
Axylo_RS09250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_RS09255	COG2706	6-phosphogluconolactonase activity
Axylo_RS09260	COG4214	carbohydrate transport
Axylo_RS09265	COG1129	ABC transporter
Axylo_RS09270	COG4213	ABC transporter substrate-binding protein
Axylo_RS09290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS09295	COG0583	DNA-binding transcription factor activity
Axylo_RS09300	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS09305	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS09310	COG0183	Belongs to the thiolase family
Axylo_RS09320	COG1802	Transcriptional regulator
Axylo_RS09330	COG1024	Enoyl-CoA hydratase
Axylo_RS09335	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_RS09345	COG0667	Aldo Keto reductase
Axylo_RS09355	COG4120	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS09370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS09380	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Axylo_RS09400	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Axylo_RS09405	COG0725	ABC transporter, periplasmic molybdate-binding protein
Axylo_RS09410	COG4149	molybdate abc transporter
Axylo_RS09415	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Axylo_RS09440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_RS09445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_RS09455	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Axylo_RS09460	COG0736	holo-[acyl-carrier-protein] synthase activity
Axylo_RS09475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Axylo_RS09485	COG0473	3-isopropylmalate dehydrogenase activity
Axylo_RS09490	COG0583	DNA-binding transcription factor activity
Axylo_RS09495	COG1858	cytochrome C peroxidase
Axylo_RS09500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Axylo_RS09500	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Axylo_RS09505	COG2224	Isocitrate lyase
Axylo_RS09510	COG0583	DNA-binding transcription factor activity
Axylo_RS09525	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Axylo_RS09540	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Axylo_RS09540	COG4106	trans-aconitate 2-methyltransferase activity
Axylo_RS09545	COG4106	trans-aconitate 2-methyltransferase activity
Axylo_RS09545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Axylo_RS09555	COG0156	8-amino-7-oxononanoate synthase activity
Axylo_RS09575	COG3278	Belongs to the heme-copper respiratory oxidase family
Axylo_RS09595	COG0348	domain, Protein
Axylo_RS09615	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS09640	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_RS09650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS09660	COG0765	amino acid transport
Axylo_RS09665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS09670	COG1396	sequence-specific DNA binding
Axylo_RS09695	COG3546	catalase activity
Axylo_RS09715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Axylo_RS09720	COG0438	transferase activity, transferring glycosyl groups
Axylo_RS09740	COG1566	PFAM secretion protein HlyD family protein
Axylo_RS09755	COG0583	DNA-binding transcription factor activity
Axylo_RS09760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS09765	COG0586	Pfam SNARE associated Golgi protein
Axylo_RS09780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS09795	COG4608	Belongs to the ABC transporter superfamily
Axylo_RS09800	COG0444	Belongs to the ABC transporter superfamily
Axylo_RS09805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS09810	COG0601	transmembrane transport
Axylo_RS09815	COG0583	DNA-binding transcription factor activity
Axylo_RS09820	COG1764	response to oxidative stress
Axylo_RS09825	COG2205	protein histidine kinase activity
Axylo_RS09865	COG1802	Transcriptional regulator
Axylo_RS09880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Axylo_RS09895	COG0583	DNA-binding transcription factor activity
Axylo_RS09905	COG2084	Dehydrogenase
Axylo_RS09915	COG1917	Cupin 2, conserved barrel domain protein
Axylo_RS09915	COG2207	Transcriptional regulator
Axylo_RS09930	COG2267	carboxylic ester hydrolase activity
Axylo_RS09955	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS09960	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS09965	COG0840	transmembrane signaling receptor activity
Axylo_RS10000	COG3188	usher protein
Axylo_RS10005	COG3121	Chaperone
Axylo_RS10035	COG2197	response regulator
Axylo_RS10045	COG5001	Diguanylate cyclase
Axylo_RS10045	COG3300	MHYT domain
Axylo_RS10055	COG3539	Fimbrial protein
Axylo_RS10065	COG3188	usher protein
Axylo_RS10085	COG0642	Histidine kinase
Axylo_RS10090	COG1475	DNA binding
Axylo_RS10095	COG3969	phosphoadenosine phosphosulfate
Axylo_RS10100	COG1971	Probably functions as a manganese efflux pump
Axylo_RS10105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Axylo_RS10160	COG2321	neutral zinc metallopeptidase
Axylo_RS10165	COG0009	L-threonylcarbamoyladenylate synthase
Axylo_RS10170	COG1994	Peptidase M50
Axylo_RS10175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_RS10180	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Axylo_RS10190	COG2850	peptidyl-arginine hydroxylation
Axylo_RS10195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Axylo_RS10215	COG0583	DNA-binding transcription factor activity
Axylo_RS10250	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS10255	COG0583	DNA-binding transcription factor activity
Axylo_RS10265	COG3360	Dodecin
Axylo_RS10305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_RS10310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Axylo_RS10350	COG0668	transmembrane transport
Axylo_RS10370	COG0483	inositol monophosphate 1-phosphatase activity
Axylo_RS10375	COG1253	flavin adenine dinucleotide binding
Axylo_RS10380	COG1968	undecaprenyl-diphosphatase activity
Axylo_RS10385	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Axylo_RS10390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Axylo_RS10400	COG0215	cysteine-tRNA ligase activity
Axylo_RS10410	COG0825	malonyl-CoA metabolic process
Axylo_RS10415	COG0037	tRNA processing
Axylo_RS10420	COG0527	aspartate kinase activity
Axylo_RS10440	COG0784	Response regulator, receiver
Axylo_RS10440	COG2205	protein histidine kinase activity
Axylo_RS10450	COG2205	protein histidine kinase activity
Axylo_RS10450	COG0784	Response regulator, receiver
Axylo_RS10460	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Axylo_RS10470	COG1309	transcriptional regulator
Axylo_RS10500	COG0456	acetyltransferase
Axylo_RS10510	COG0583	DNA-binding transcription factor activity
Axylo_RS10535	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Axylo_RS10545	COG1414	Transcriptional regulator
Axylo_RS10555	COG1024	Enoyl-CoA hydratase
Axylo_RS10560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Axylo_RS10565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Axylo_RS10575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Axylo_RS10580	COG3395	kinase activity
Axylo_RS10590	COG1132	(ABC) transporter
Axylo_RS10600	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS10610	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_RS10625	COG0183	Belongs to the thiolase family
Axylo_RS10630	COG1024	Enoyl-CoA hydratase
Axylo_RS10630	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_RS10640	COG1024	Enoyl-CoA hydratase
Axylo_RS10640	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_RS10650	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS10655	COG1309	transcriptional regulator
Axylo_RS10665	COG2197	response regulator
Axylo_RS10670	COG2197	response regulator
Axylo_RS10675	COG0297	glycogen (starch) synthase activity
Axylo_RS10680	COG0110	maltose O-acetyltransferase activity
Axylo_RS10685	COG0463	Glycosyl transferase, family 2
Axylo_RS10710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_RS10730	COG1051	belongs to the nudix hydrolase family
Axylo_RS10735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Axylo_RS10755	COG0166	Belongs to the GPI family
Axylo_RS10760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Axylo_RS10765	COG1045	serine acetyltransferase
Axylo_RS10770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Axylo_RS10775	COG0483	inositol monophosphate 1-phosphatase activity
Axylo_RS10785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Axylo_RS10805	COG0598	Magnesium transport protein CorA
Axylo_RS10825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS10830	COG4172	Belongs to the ABC transporter superfamily
Axylo_RS10835	COG1846	Transcriptional regulator
Axylo_RS10880	COG4964	Belongs to the GSP D family
Axylo_RS10935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Axylo_RS10950	COG3384	dioxygenase
Axylo_RS10960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Axylo_RS10970	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS10975	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS11005	COG0604	alcohol dehydrogenase
Axylo_RS11005	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS11005	COG3321	synthase
Axylo_RS11020	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS11030	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS11040	COG3246	L-lysine catabolic process to acetate
Axylo_RS11045	COG0371	Dehydrogenase
Axylo_RS11050	COG1802	Transcriptional regulator
Axylo_RS11055	COG3959	Transketolase, thiamine diphosphate binding domain
Axylo_RS11060	COG3958	Transketolase
Axylo_RS11065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Axylo_RS11075	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS11080	COG0179	Fumarylacetoacetate (FAA) hydrolase
Axylo_RS11085	COG1414	Transcriptional regulator
Axylo_RS11110	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS11140	COG0625	glutathione transferase activity
Axylo_RS11155	COG3530	Putative quorum-sensing-regulated virulence factor
Axylo_RS11165	COG2814	Major facilitator Superfamily
Axylo_RS11200	COG0443	Heat shock 70 kDa protein
Axylo_RS11205	COG0494	nUDIX hydrolase
Axylo_RS11215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Axylo_RS11220	COG0477	Major facilitator Superfamily
Axylo_RS11230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Axylo_RS11240	COG0542	response to heat
Axylo_RS11265	COG5441	Belongs to the UPF0261 family
Axylo_RS11270	COG5564	TIM-barrel signal transduction protein
Axylo_RS11285	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_RS11300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Axylo_RS11310	COG1562	ergosterol biosynthetic process
Axylo_RS11320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Axylo_RS11325	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS11335	COG3971	2-oxopent-4-enoate hydratase activity
Axylo_RS11350	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_RS11355	COG3384	dioxygenase
Axylo_RS11385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Axylo_RS11395	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS11405	COG2186	Transcriptional regulator
Axylo_RS11410	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Axylo_RS11415	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS11430	COG0583	DNA-binding transcription factor activity
Axylo_RS11435	COG0268	Binds directly to 16S ribosomal RNA
Axylo_RS11445	COG0728	peptidoglycan biosynthetic process
Axylo_RS11455	COG0563	adenylate kinase activity
Axylo_RS11460	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Axylo_RS11465	COG2835	tetraacyldisaccharide 4'-kinase activity
Axylo_RS11475	COG1663	tetraacyldisaccharide 4'-kinase activity
Axylo_RS11485	COG0811	peptide transport
Axylo_RS11490	COG1570	exodeoxyribonuclease VII activity
Axylo_RS11500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Axylo_RS11510	COG0038	chloride channel
Axylo_RS11515	COG0183	Belongs to the thiolase family
Axylo_RS11525	COG1278	Cold shock
Axylo_RS11530	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Axylo_RS11535	COG2373	Large extracellular alpha-helical protein
Axylo_RS11540	COG4953	penicillin-binding protein 1C
Axylo_RS11545	COG0542	response to heat
Axylo_RS11550	COG2995	paraquat-inducible protein a
Axylo_RS11555	COG3008	intermembrane lipid transfer
Axylo_RS11565	COG0506	proline dehydrogenase activity
Axylo_RS11565	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Axylo_RS11565	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Axylo_RS11600	COG2271	Major facilitator Superfamily
Axylo_RS11640	COG1914	H( )-stimulated, divalent metal cation uptake system
Axylo_RS11645	COG1764	response to oxidative stress
Axylo_RS11660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS11665	COG0765	amino acid transport
Axylo_RS11670	COG0765	amino acid transport
Axylo_RS11675	COG1126	abc transporter atp-binding protein
Axylo_RS11680	COG1902	pentaerythritol trinitrate reductase activity
Axylo_RS11730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Axylo_RS11735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Axylo_RS11740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Axylo_RS11745	COG0196	riboflavin kinase activity
Axylo_RS11750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Axylo_RS11755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Axylo_RS11755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Axylo_RS11770	COG0210	DNA helicase
Axylo_RS11780	COG1858	cytochrome C peroxidase
Axylo_RS11785	COG4771	TonB-dependent receptor
Axylo_RS11790	COG4771	TonB-dependent receptor
Axylo_RS11805	COG0488	(ABC) transporter
Axylo_RS11810	COG2890	protein-(glutamine-N5) methyltransferase activity
Axylo_RS11820	COG2171	N-acyltransferase activity
Axylo_RS11855	COG2271	Major facilitator Superfamily
Axylo_RS11860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Axylo_RS11870	COG0277	FAD linked oxidase domain protein
Axylo_RS11895	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Axylo_RS11935	COG0583	DNA-binding transcription factor activity
Axylo_RS11945	COG0251	oxidation-reduction process
Axylo_RS11970	COG1278	Cold shock
Axylo_RS11980	COG1278	Cold shock
Axylo_RS11990	COG0501	Belongs to the peptidase M48B family
Axylo_RS11995	COG0544	peptidyl-prolyl cis-trans isomerase activity
Axylo_RS12000	COG0740	serine-type endopeptidase activity
Axylo_RS12005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Axylo_RS12010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Axylo_RS12015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Axylo_RS12025	COG0556	nucleotide-excision repair
Axylo_RS12030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Axylo_RS12040	COG1104	cysteine desulfurase activity
Axylo_RS12045	COG0822	iron-sulfur transferase activity
Axylo_RS12050	COG0316	Belongs to the HesB IscA family
Axylo_RS12055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Axylo_RS12060	COG0443	Heat shock 70 kDa protein
Axylo_RS12065	COG0633	Ferredoxin
Axylo_RS12070	COG2975	iron-sulfur cluster assembly
Axylo_RS12075	COG1803	Methylglyoxal synthase
Axylo_RS12085	COG1024	Enoyl-CoA hydratase
Axylo_RS12115	COG1022	Amp-dependent synthetase and ligase
Axylo_RS12120	COG0183	Belongs to the thiolase family
Axylo_RS12125	COG1309	transcriptional regulator
Axylo_RS12130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Axylo_RS12135	COG3135	benzoate transporter
Axylo_RS12150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Axylo_RS12155	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS12165	COG2271	Major facilitator Superfamily
Axylo_RS12190	COG1136	(ABC) transporter
Axylo_RS12195	COG0084	hydrolase, TatD family'
Axylo_RS12205	COG0745	RESPONSE REGULATOR receiver
Axylo_RS12210	COG4771	TonB-dependent receptor
Axylo_RS12215	COG4607	ABC-type enterochelin transport system periplasmic component
Axylo_RS12220	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_RS12225	COG4605	iron ion homeostasis
Axylo_RS12230	COG4604	ABC transporter, ATP-binding protein
Axylo_RS12245	COG1595	DNA-templated transcription, initiation
Axylo_RS12275	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Axylo_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS12310	COG0459	protein refolding
Axylo_RS12315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Axylo_RS12325	COG2249	NAD(P)H dehydrogenase (quinone) activity
Axylo_RS12345	COG3093	addiction module antidote protein HigA
Axylo_RS12365	COG0159	tryptophan synthase activity
Axylo_RS12375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Axylo_RS12380	COG0477	Major facilitator Superfamily
Axylo_RS12385	COG0583	DNA-binding transcription factor activity
Axylo_RS12395	COG0583	DNA-binding transcription factor activity
Axylo_RS12405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Axylo_RS12425	COG0613	PHP domain protein
Axylo_RS12435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_RS12440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Axylo_RS12440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Axylo_RS12450	COG0047	phosphoribosylformylglycinamidine synthase activity
Axylo_RS12450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Axylo_RS12475	COG0642	Histidine kinase
Axylo_RS12495	COG0583	DNA-binding transcription factor activity
Axylo_RS12510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Axylo_RS12520	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS12545	COG0745	RESPONSE REGULATOR receiver
Axylo_RS12545	COG2205	protein histidine kinase activity
Axylo_RS12545	COG3292	Two component regulator propeller
Axylo_RS12550	COG2198	Histidine kinase
Axylo_RS12550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS12550	COG0784	Response regulator, receiver
Axylo_RS12550	COG2205	protein histidine kinase activity
Axylo_RS12580	COG1953	Uracil, thiamine, allantoin
Axylo_RS12590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Axylo_RS12635	COG4774	siderophore transport
Axylo_RS12640	COG5001	Diguanylate cyclase
Axylo_RS12665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Axylo_RS12680	COG3618	amidohydrolase
Axylo_RS12685	COG0583	DNA-binding transcription factor activity
Axylo_RS12695	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS12705	COG1024	Enoyl-CoA hydratase
Axylo_RS12740	COG0583	DNA-binding transcription factor activity
Axylo_RS12765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Axylo_RS12780	COG4774	siderophore transport
Axylo_RS12820	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS12825	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Axylo_RS12830	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS12835	COG0583	DNA-binding transcription factor activity
Axylo_RS12850	COG0747	negative chemotaxis
Axylo_RS12855	COG4608	Belongs to the ABC transporter superfamily
Axylo_RS12865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS12870	COG0601	transmembrane transport
Axylo_RS12875	COG2072	flavoprotein involved in K transport
Axylo_RS12905	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS12910	COG3048	D-serine ammonia-lyase activity
Axylo_RS12915	COG0583	DNA-binding transcription factor activity
Axylo_RS12940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Axylo_RS12950	COG0583	DNA-binding transcription factor activity
Axylo_RS12980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Axylo_RS12980	COG0519	Catalyzes the synthesis of GMP from XMP
Axylo_RS12990	COG1002	Type II restriction enzyme, methylase subunits
Axylo_RS13000	COG0640	Transcriptional regulator
Axylo_RS13005	COG0583	DNA-binding transcription factor activity
Axylo_RS13010	COG1335	isochorismatase
Axylo_RS13040	COG2207	Transcriptional regulator
Axylo_RS13055	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS13090	COG0583	DNA-binding transcription factor activity
Axylo_RS13115	COG0477	Major facilitator Superfamily
Axylo_RS13150	COG0456	acetyltransferase
Axylo_RS13165	COG1199	ATP-dependent helicase activity
Axylo_RS13180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Axylo_RS13190	COG0667	Aldo Keto reductase
Axylo_RS13210	COG0587	DNA-directed DNA polymerase activity
Axylo_RS13230	COG0833	amino acid
Axylo_RS13235	COG0400	carboxylic ester hydrolase activity
Axylo_RS13255	COG0028	Belongs to the TPP enzyme family
Axylo_RS13270	COG1566	PFAM secretion protein HlyD family protein
Axylo_RS13280	COG1289	transmembrane transporter activity
Axylo_RS13290	COG0720	synthase
Axylo_RS13295	COG0602	queuosine metabolic process
Axylo_RS13310	COG1902	pentaerythritol trinitrate reductase activity
Axylo_RS13340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Axylo_RS13355	COG0842	Transport permease protein
Axylo_RS13360	COG1131	(ABC) transporter
Axylo_RS13375	COG2130	NADP-dependent
Axylo_RS13400	COG3842	ATPase activity
Axylo_RS13405	COG3842	ATPase activity
Axylo_RS13415	COG0395	ABC-type sugar transport system, permease component
Axylo_RS13450	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS13475	COG3634	alkyl hydroperoxide reductase activity
Axylo_RS13480	COG1959	2 iron, 2 sulfur cluster binding
Axylo_RS13485	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS13520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS13525	COG0420	3'-5' exonuclease activity
Axylo_RS13550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Axylo_RS13550	COG2111	Na H antiporter
Axylo_RS13555	COG1006	Multisubunit Na H antiporter MnhC subunit
Axylo_RS13560	COG0651	ATP synthesis coupled electron transport
Axylo_RS13565	COG1863	multisubunit Na H antiporter MnhE subunit
Axylo_RS13570	COG2212	antiporter activity
Axylo_RS13575	COG1320	monovalent cation:proton antiporter activity
Axylo_RS13595	COG1619	proteins homologs of microcin C7 resistance protein MccF
Axylo_RS13615	COG0488	(ABC) transporter
Axylo_RS13650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_RS13655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Axylo_RS13665	COG2252	PERMEase
Axylo_RS13670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Axylo_RS13675	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Axylo_RS13685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Axylo_RS13710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Axylo_RS13715	COG0789	Transcriptional regulator
Axylo_RS13730	COG0678	peroxiredoxin activity
Axylo_RS13730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Axylo_RS13740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Axylo_RS13745	COG0584	glycerophosphoryl diester phosphodiesterase
Axylo_RS13755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_RS13765	COG4181	ATPase activity
Axylo_RS13775	COG1178	ABC-type Fe3 transport system permease component
Axylo_RS13780	COG3842	ATPase activity
Axylo_RS13785	COG0583	DNA-binding transcription factor activity
Axylo_RS13790	COG0560	Phosphoserine phosphatase
Axylo_RS13805	COG0583	DNA-binding transcription factor activity
Axylo_RS13820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Axylo_RS13835	COG0583	DNA-binding transcription factor activity
Axylo_RS13840	COG4336	lyase activity
Axylo_RS13870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS13890	COG2816	NAD+ diphosphatase activity
Axylo_RS13910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS13915	COG0765	amino acid transport
Axylo_RS13920	COG1126	abc transporter atp-binding protein
Axylo_RS13925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Axylo_RS13930	COG1758	RNA polymerase activity
Axylo_RS13935	COG0194	GDP metabolic process
Axylo_RS13940	COG3258	Cytochrome c
Axylo_RS13945	COG2863	cytochrome
Axylo_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS13955	COG2831	hemolysin activation secretion protein
Axylo_RS13960	COG3210	domain, Protein
Axylo_RS13970	COG0791	NLP P60 protein
Axylo_RS13985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Axylo_RS13990	COG0833	amino acid
Axylo_RS13995	COG1561	YicC-like family, N-terminal region
Axylo_RS14000	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Axylo_RS14010	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS14020	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Axylo_RS14025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Axylo_RS14030	COG0174	glutamine synthetase
Axylo_RS14040	COG2204	response regulator
Axylo_RS14045	COG0583	DNA-binding transcription factor activity
Axylo_RS14050	COG1741	Belongs to the pirin family
Axylo_RS14055	COG1741	Belongs to the pirin family
Axylo_RS14060	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Axylo_RS14065	COG1690	Belongs to the RtcB family
Axylo_RS14070	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS14075	COG3842	ATPase activity
Axylo_RS14080	COG4149	molybdate abc transporter
Axylo_RS14085	COG1840	ABC-type Fe3 transport system, periplasmic component
Axylo_RS14095	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS14110	COG0583	DNA-binding transcription factor activity
Axylo_RS14130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Axylo_RS14140	COG0783	Belongs to the Dps family
Axylo_RS14150	COG0457	Tetratricopeptide repeat
Axylo_RS14155	COG0438	transferase activity, transferring glycosyl groups
Axylo_RS14180	COG1560	Kdo2-lipid A biosynthetic process
Axylo_RS14180	COG4783	chaperone-mediated protein folding
Axylo_RS14200	COG0745	RESPONSE REGULATOR receiver
Axylo_RS14205	COG2205	protein histidine kinase activity
Axylo_RS14220	COG3842	ATPase activity
Axylo_RS14225	COG0395	ABC-type sugar transport system, permease component
Axylo_RS14230	COG1175	transmembrane transport
Axylo_RS14235	COG1653	transport
Axylo_RS14245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Axylo_RS14255	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS14285	COG1794	racemase activity, acting on amino acids and derivatives
Axylo_RS14290	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_RS14300	COG0583	DNA-binding transcription factor activity
Axylo_RS14305	COG0625	glutathione transferase activity
Axylo_RS14310	COG2133	pyrroloquinoline quinone binding
Axylo_RS14320	COG0697	spore germination
Axylo_RS14325	COG2363	Small membrane protein
Axylo_RS14340	COG1414	Transcriptional regulator
Axylo_RS14345	COG0010	Belongs to the arginase family
Axylo_RS14350	COG1464	Belongs to the NlpA lipoprotein family
Axylo_RS14360	COG2814	Major facilitator Superfamily
Axylo_RS14370	COG1408	metallophosphoesterase
Axylo_RS14400	COG0688	phosphatidylethanolamine metabolic process
Axylo_RS14410	COG0488	(ABC) transporter
Axylo_RS14435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS14440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Axylo_RS14445	COG3300	MHYT domain
Axylo_RS14445	COG5001	Diguanylate cyclase
Axylo_RS14460	COG2814	Major facilitator Superfamily
Axylo_RS14485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Axylo_RS14490	COG2204	response regulator
Axylo_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS14545	COG0693	protein deglycase activity
Axylo_RS14560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Axylo_RS14570	COG1289	transmembrane transporter activity
Axylo_RS14575	COG3300	MHYT domain
Axylo_RS14575	COG5001	Diguanylate cyclase
Axylo_RS14625	COG1253	flavin adenine dinucleotide binding
Axylo_RS14635	COG2205	protein histidine kinase activity
Axylo_RS14690	COG3706	GGDEF domain
Axylo_RS14695	COG0789	Transcriptional regulator
Axylo_RS14705	COG3706	GGDEF domain
Axylo_RS14750	COG0628	permease
Axylo_RS14775	COG0531	amino acid
Axylo_RS14785	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_RS14790	COG4608	Belongs to the ABC transporter superfamily
Axylo_RS14795	COG0444	Belongs to the ABC transporter superfamily
Axylo_RS14805	COG0601	transmembrane transport
Axylo_RS14810	COG0747	negative chemotaxis
Axylo_RS14820	COG0251	oxidation-reduction process
Axylo_RS14845	COG0179	Fumarylacetoacetate (FAA) hydrolase
Axylo_RS14860	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Axylo_RS14885	COG3971	2-oxopent-4-enoate hydratase activity
Axylo_RS14915	COG0625	glutathione transferase activity
Axylo_RS14930	COG0477	Major facilitator Superfamily
Axylo_RS14940	COG0579	oxidoreductase
Axylo_RS14955	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS14980	COG0071	Belongs to the small heat shock protein (HSP20) family
Axylo_RS15015	COG1914	H( )-stimulated, divalent metal cation uptake system
Axylo_RS15020	COG0589	response to stress
Axylo_RS15035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Axylo_RS15055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Axylo_RS15055	COG0517	IMP dehydrogenase activity
Axylo_RS15055	COG0617	tRNA 3'-terminal CCA addition
Axylo_RS15060	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Axylo_RS15065	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Axylo_RS15085	COG0589	response to stress
Axylo_RS15110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Axylo_RS15160	COG2192	nodulation
Axylo_RS15170	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Axylo_RS15190	COG5265	(ABC) transporter
Axylo_RS15200	COG1215	transferase activity, transferring glycosyl groups
Axylo_RS15210	COG0668	transmembrane transport
Axylo_RS15220	COG0166	Belongs to the GPI family
Axylo_RS15230	COG3685	Protein conserved in bacteria
Axylo_RS15245	COG0387	Pfam Sodium calcium exchanger
Axylo_RS15250	COG3568	Endonuclease Exonuclease Phosphatase
Axylo_RS15255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Axylo_RS15260	COG0392	lysyltransferase activity
Axylo_RS15265	COG0297	glycogen (starch) synthase activity
Axylo_RS15270	COG0366	Alpha amylase catalytic
Axylo_RS15275	COG0366	Alpha amylase catalytic
Axylo_RS15280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Axylo_RS15290	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Axylo_RS15295	COG1640	4-alpha-glucanotransferase
Axylo_RS15305	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Axylo_RS15325	COG1126	abc transporter atp-binding protein
Axylo_RS15330	COG0765	amino acid transport
Axylo_RS15335	COG4597	amino acid ABC transporter
Axylo_RS15340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS15345	COG0626	cystathionine gamma-synthase activity
Axylo_RS15350	COG0583	DNA-binding transcription factor activity
Axylo_RS15355	COG4771	TonB-dependent receptor
Axylo_RS15365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Axylo_RS15375	COG2358	TRAP transporter, solute receptor (TAXI family
Axylo_RS15380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_RS15385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_RS15395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Axylo_RS15400	COG0519	Catalyzes the synthesis of GMP from XMP
Axylo_RS15400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Axylo_RS15410	COG1276	copper resistance
Axylo_RS15415	COG2372	response to copper ion
Axylo_RS15430	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS15435	COG2721	sulfolactate sulfo-lyase activity
Axylo_RS15455	COG2188	Transcriptional regulator
Axylo_RS15460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS15465	COG0436	Aminotransferase
Axylo_RS15470	COG4597	amino acid ABC transporter
Axylo_RS15475	COG0765	amino acid transport
Axylo_RS15480	COG1126	abc transporter atp-binding protein
Axylo_RS15495	COG0745	RESPONSE REGULATOR receiver
Axylo_RS15505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_RS15510	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
Axylo_RS15515	COG1120	ATPase activity
Axylo_RS15520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Axylo_RS15535	COG0586	Pfam SNARE associated Golgi protein
Axylo_RS15540	COG0390	transport system, permease component
Axylo_RS15545	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Axylo_RS15550	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Axylo_RS15590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Axylo_RS15595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_RS15600	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_RS15610	COG1126	abc transporter atp-binding protein
Axylo_RS15615	COG0765	amino acid transport
Axylo_RS15620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS15625	COG2070	2-Nitropropane dioxygenase
Axylo_RS15630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_RS15640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Axylo_RS15670	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Axylo_RS15675	COG0583	DNA-binding transcription factor activity
Axylo_RS15690	COG4191	Histidine kinase
Axylo_RS15695	COG4566	intracellular signal transduction
Axylo_RS15720	COG4774	siderophore transport
Axylo_RS15755	COG0583	DNA-binding transcription factor activity
Axylo_RS15775	COG1126	abc transporter atp-binding protein
Axylo_RS15785	COG0765	amino acid transport
Axylo_RS15790	COG0436	Aminotransferase
Axylo_RS15795	COG0277	FAD linked oxidase domain protein
Axylo_RS15820	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Axylo_RS15845	COG0251	oxidation-reduction process
Axylo_RS15880	COG4948	Mandelate Racemase Muconate Lactonizing
Axylo_RS15890	COG1802	Transcriptional regulator
Axylo_RS15895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_RS15910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Axylo_RS15935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_RS15940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Axylo_RS15945	COG1116	anion transmembrane transporter activity
Axylo_RS15980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS15985	COG4597	amino acid ABC transporter
Axylo_RS15990	COG3154	lipid carrier protein
Axylo_RS15995	COG0826	peptidase U32
Axylo_RS16000	COG0826	peptidase U32
Axylo_RS16005	COG2197	response regulator
Axylo_RS16010	COG3850	Histidine kinase
Axylo_RS16015	COG1763	Mo-molybdopterin cofactor biosynthetic process
Axylo_RS16020	COG0288	reversible hydration of carbon dioxide
Axylo_RS16025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Axylo_RS16030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_RS16035	COG2181	nitrate reductase activity
Axylo_RS16040	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Axylo_RS16045	COG1140	nitrate reductase beta subunit
Axylo_RS16050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Axylo_RS16055	COG2223	nitrite transmembrane transporter activity
Axylo_RS16080	COG0583	DNA-binding transcription factor activity
Axylo_RS16085	COG0583	DNA-binding transcription factor activity
Axylo_RS16095	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS16125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS16145	COG2070	2-Nitropropane dioxygenase
Axylo_RS16150	COG5002	protein histidine kinase activity
Axylo_RS16155	COG0745	RESPONSE REGULATOR receiver
Axylo_RS16160	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
Axylo_RS16165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Axylo_RS16175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Axylo_RS16180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Axylo_RS16195	COG0783	Belongs to the Dps family
Axylo_RS16215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS16220	COG0697	spore germination
Axylo_RS16225	COG2879	small protein
Axylo_RS16230	COG1966	Carbon starvation protein
Axylo_RS16250	COG0697	spore germination
Axylo_RS16255	COG0583	DNA-binding transcription factor activity
Axylo_RS16265	COG4521	taurine ABC transporter
Axylo_RS16270	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Axylo_RS16275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_RS16305	COG0523	cobalamin synthesis protein
Axylo_RS16310	COG1228	amidohydrolase
Axylo_RS16315	COG4172	Belongs to the ABC transporter superfamily
Axylo_RS16320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS16325	COG0601	transmembrane transport
Axylo_RS16330	COG0747	negative chemotaxis
Axylo_RS16345	COG1414	Transcriptional regulator
Axylo_RS16350	COG0513	Belongs to the DEAD box helicase family
Axylo_RS16370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS16380	COG0840	transmembrane signaling receptor activity
Axylo_RS16390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Axylo_RS16420	COG2814	Major facilitator Superfamily
Axylo_RS16425	COG0386	Belongs to the glutathione peroxidase family
Axylo_RS16430	COG1522	sequence-specific DNA binding
Axylo_RS16440	COG0625	glutathione transferase activity
Axylo_RS16475	COG0583	DNA-binding transcription factor activity
Axylo_RS16490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Axylo_RS16500	COG0010	Belongs to the arginase family
Axylo_RS16505	COG1126	abc transporter atp-binding protein
Axylo_RS16510	COG0765	amino acid transport
Axylo_RS16515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS16530	COG0084	hydrolase, TatD family'
Axylo_RS16535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Axylo_RS16540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Axylo_RS16545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Axylo_RS16570	COG1024	Enoyl-CoA hydratase
Axylo_RS16570	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_RS16580	COG2914	Belongs to the UPF0125 (RnfH) family
Axylo_RS16585	COG2867	negative regulation of translational initiation
Axylo_RS16590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Axylo_RS16610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Axylo_RS16610	COG0519	Catalyzes the synthesis of GMP from XMP
Axylo_RS16615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Axylo_RS16615	COG2169	Transcriptional regulator
Axylo_RS16655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Axylo_RS16660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Axylo_RS16675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Axylo_RS16680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Axylo_RS16690	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Axylo_RS16695	COG0750	zinc metalloprotease
Axylo_RS16700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Axylo_RS16710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Axylo_RS16715	COG0233	cytoplasmic translational termination
Axylo_RS16720	COG0528	UMP kinase activity
Axylo_RS16725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Axylo_RS16730	COG0052	Belongs to the universal ribosomal protein uS2 family
Axylo_RS16735	COG0024	Methionine aminopeptidase
Axylo_RS16740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Axylo_RS16750	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Axylo_RS16760	COG1451	nucleotide metabolic process
Axylo_RS16770	COG1286	toxin biosynthetic process
Axylo_RS16780	COG0285	dihydrofolate synthase activity
Axylo_RS16790	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS16795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS16805	COG1414	Transcriptional regulator
Axylo_RS16815	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Axylo_RS16835	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Axylo_RS16845	COG1677	Flagellar hook-basal body complex protein FliE
Axylo_RS16850	COG1766	The M ring may be actively involved in energy transduction
Axylo_RS16855	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Axylo_RS16880	COG1580	Controls the rotational direction of flagella during chemotaxis
Axylo_RS16890	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Axylo_RS16915	COG0840	transmembrane signaling receptor activity
Axylo_RS16920	COG0840	transmembrane signaling receptor activity
Axylo_RS16930	COG0840	transmembrane signaling receptor activity
Axylo_RS16935	COG0840	transmembrane signaling receptor activity
Axylo_RS16970	COG4787	bacterial-type flagellum-dependent cell motility
Axylo_RS16985	COG1558	bacterial-type flagellum-dependent cell motility
Axylo_RS17000	COG2747	anti-sigma28 factor FlgM
Axylo_RS17025	COG0840	transmembrane signaling receptor activity
Axylo_RS17030	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Axylo_RS17035	COG0745	RESPONSE REGULATOR receiver
Axylo_RS17040	COG2201	protein-glutamate methylesterase activity
Axylo_RS17045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Axylo_RS17050	COG0840	transmembrane signaling receptor activity
Axylo_RS17055	COG0835	chemotaxis
Axylo_RS17065	COG0745	RESPONSE REGULATOR receiver
Axylo_RS17090	COG1191	sigma factor activity
Axylo_RS17095	COG4797	methyltransferase
Axylo_RS17095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Axylo_RS17125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Axylo_RS17130	COG0508	dehydrogenase complex catalyzes the overall conversion of
Axylo_RS17135	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Axylo_RS17145	COG4566	intracellular signal transduction
Axylo_RS17150	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Axylo_RS17155	COG0339	signal peptide processing
Axylo_RS17165	COG1999	signal sequence binding
Axylo_RS17170	COG2261	transglycosylase associated protein
Axylo_RS17190	COG0583	DNA-binding transcription factor activity
Axylo_RS17195	COG1187	pseudouridine synthase activity
Axylo_RS17200	COG3161	chorismate lyase activity
Axylo_RS17205	COG0477	Major facilitator Superfamily
Axylo_RS17225	COG4681	YaeQ
Axylo_RS17230	COG4172	Belongs to the ABC transporter superfamily
Axylo_RS17235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS17240	COG0601	transmembrane transport
Axylo_RS17245	COG0747	negative chemotaxis
Axylo_RS17255	COG0583	DNA-binding transcription factor activity
Axylo_RS17295	COG2165	general secretion pathway protein
Axylo_RS17365	COG0668	transmembrane transport
Axylo_RS17370	COG0165	Argininosuccinate lyase
Axylo_RS17390	COG0022	dehydrogenase e1 component
Axylo_RS17400	COG4774	siderophore transport
Axylo_RS17425	COG0789	Transcriptional regulator
Axylo_RS17435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Axylo_RS17445	COG2271	Major facilitator Superfamily
Axylo_RS17455	COG0307	riboflavin synthase, alpha
Axylo_RS17470	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS17500	COG2070	2-Nitropropane dioxygenase
Axylo_RS17550	COG0154	amidase activity
Axylo_RS17555	COG2814	Major facilitator Superfamily
Axylo_RS17590	COG2814	Major facilitator Superfamily
Axylo_RS17605	COG0583	DNA-binding transcription factor activity
Axylo_RS17620	COG0583	DNA-binding transcription factor activity
Axylo_RS17645	COG2059	Chromate
Axylo_RS17660	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS17680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_RS17690	COG5265	(ABC) transporter
Axylo_RS17740	COG2188	Transcriptional regulator
Axylo_RS17755	COG0477	Major facilitator Superfamily
Axylo_RS17760	COG0235	Class ii aldolase
Axylo_RS17800	COG2610	gluconate transmembrane transporter activity
Axylo_RS17805	COG0583	DNA-binding transcription factor activity
Axylo_RS17810	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS17815	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
Axylo_RS17830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS17855	COG1024	Enoyl-CoA hydratase
Axylo_RS17860	COG5001	Diguanylate cyclase
Axylo_RS17865	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS17870	COG0129	dihydroxy-acid dehydratase activity
Axylo_RS17880	COG0583	DNA-binding transcription factor activity
Axylo_RS17885	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_RS17890	COG3246	L-lysine catabolic process to acetate
Axylo_RS17910	COG3381	protein complex oligomerization
Axylo_RS17920	COG3005	denitrification pathway
Axylo_RS17925	COG4133	protoheme IX ABC transporter activity
Axylo_RS17930	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Axylo_RS17940	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Axylo_RS17945	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Axylo_RS17955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_RS17960	COG3088	subunit of a heme lyase
Axylo_RS17985	COG0583	DNA-binding transcription factor activity
Axylo_RS18010	COG4172	Belongs to the ABC transporter superfamily
Axylo_RS18015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Axylo_RS18020	COG0583	DNA-binding transcription factor activity
Axylo_RS18025	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS18030	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS18045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Axylo_RS18055	COG1063	alcohol dehydrogenase
Axylo_RS18075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Axylo_RS18080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_RS18085	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS18090	COG2207	Transcriptional regulator
Axylo_RS18125	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS18130	COG3328	transposase activity
Axylo_RS18145	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Axylo_RS18150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Axylo_RS18160	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS18165	COG1024	Enoyl-CoA hydratase
Axylo_RS18170	COG0534	Mate efflux family protein
Axylo_RS18185	COG0697	spore germination
Axylo_RS18190	COG0697	spore germination
Axylo_RS18205	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS18220	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS18225	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Axylo_RS18250	COG1960	acyl-CoA dehydrogenase activity
Axylo_RS18270	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Axylo_RS18275	COG2814	Major facilitator Superfamily
Axylo_RS18290	COG0625	glutathione transferase activity
Axylo_RS18295	COG0583	DNA-binding transcription factor activity
Axylo_RS18300	COG0583	DNA-binding transcription factor activity
Axylo_RS18305	COG2814	Major facilitator Superfamily
Axylo_RS18310	COG0583	DNA-binding transcription factor activity
Axylo_RS18330	COG0506	proline dehydrogenase activity
Axylo_RS18335	COG0697	spore germination
Axylo_RS18340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS18345	COG1959	2 iron, 2 sulfur cluster binding
Axylo_RS18370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Axylo_RS18375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Axylo_RS18385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Axylo_RS18425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Axylo_RS18435	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS18440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Axylo_RS18450	COG1610	YqeY-like protein
Axylo_RS18490	COG0457	Tetratricopeptide repeat
Axylo_RS18495	COG1649	PFAM Uncharacterised BCR, COG1649
Axylo_RS18495	COG0726	polysaccharide deacetylase
Axylo_RS18500	COG1215	transferase activity, transferring glycosyl groups
Axylo_RS18510	COG2223	nitrite transmembrane transporter activity
Axylo_RS18515	COG1917	Cupin 2, conserved barrel domain protein
Axylo_RS18515	COG4977	sequence-specific DNA binding
Axylo_RS18525	COG1595	DNA-templated transcription, initiation
Axylo_RS18530	COG3712	iron ion homeostasis
Axylo_RS18535	COG4774	siderophore transport
Axylo_RS18540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Axylo_RS18555	COG0656	L-ascorbic acid biosynthetic process
Axylo_RS18560	COG5265	(ABC) transporter
Axylo_RS18590	COG1116	anion transmembrane transporter activity
Axylo_RS18615	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS18620	COG0583	DNA-binding transcription factor activity
Axylo_RS18650	COG1522	sequence-specific DNA binding
Axylo_RS18700	COG0384	phenazine biosynthesis protein PhzF
Axylo_RS18740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Axylo_RS18740	COG0072	phenylalanine-tRNA ligase activity
Axylo_RS18745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Axylo_RS18750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Axylo_RS18755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Axylo_RS18765	COG2960	long-chain fatty acid transporting porin activity
Axylo_RS18775	COG0347	Belongs to the P(II) protein family
Axylo_RS18780	COG0004	ammonium transporteR
Axylo_RS18785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Axylo_RS18790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Axylo_RS18805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Axylo_RS18810	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Axylo_RS18820	COG2197	response regulator
Axylo_RS18825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Axylo_RS18855	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_RS18865	COG0601	transmembrane transport
Axylo_RS18870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS18895	COG1609	Transcriptional regulator
Axylo_RS18900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Axylo_RS18905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Axylo_RS18910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_RS18915	COG0129	dihydroxy-acid dehydratase activity
Axylo_RS18920	COG0657	acetylesterase activity
Axylo_RS18920	COG2755	lipolytic protein G-D-S-L family
Axylo_RS18960	COG0135	phosphoribosylanthranilate isomerase activity
Axylo_RS18965	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Axylo_RS18970	COG0101	tRNA pseudouridine synthase activity
Axylo_RS18980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Axylo_RS19000	COG1538	Outer membrane efflux protein
Axylo_RS19010	COG2274	protein secretion by the type I secretion system
Axylo_RS19015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_RS19045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Axylo_RS19070	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Axylo_RS19080	COG1295	ribonuclease BN
Axylo_RS19090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Axylo_RS19120	COG4964	Belongs to the GSP D family
Axylo_RS19150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Axylo_RS19150	COG2755	lipolytic protein G-D-S-L family
Axylo_RS19165	COG0438	transferase activity, transferring glycosyl groups
Axylo_RS19195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Axylo_RS19200	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Axylo_RS19205	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Axylo_RS19210	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Axylo_RS19215	COG0330	HflC and HflK could
Axylo_RS19220	COG0330	HflC and HflK could
Axylo_RS19225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Axylo_RS19230	COG1923	regulation of RNA biosynthetic process
Axylo_RS19235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Axylo_RS19240	COG1160	GTP binding
Axylo_RS19245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Axylo_RS19250	COG2976	Protein conserved in bacteria
Axylo_RS19270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Axylo_RS19275	COG0105	UTP biosynthetic process
Axylo_RS19280	COG0525	valine-tRNA ligase activity
Axylo_RS19285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS19290	COG1126	abc transporter atp-binding protein
Axylo_RS19295	COG0765	amino acid transport
Axylo_RS19300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS19305	COG1396	sequence-specific DNA binding
Axylo_RS19310	COG0336	Belongs to the RNA methyltransferase TrmD family
Axylo_RS19320	COG0228	four-way junction DNA binding
Axylo_RS19330	COG0425	Belongs to the sulfur carrier protein TusA family
Axylo_RS19335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Axylo_RS19350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_RS19360	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Axylo_RS19365	COG2076	Multidrug Resistance protein
Axylo_RS19370	COG3217	Mosc domain protein beta barrel domain protein
Axylo_RS19370	COG0633	Ferredoxin
Axylo_RS19375	COG5285	phytanoyl-CoA dioxygenase
Axylo_RS19380	COG0662	Cupin 2, conserved barrel domain protein
Axylo_RS19405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Axylo_RS19410	COG2311	Membrane
Axylo_RS19415	COG1309	transcriptional regulator
Axylo_RS19440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Axylo_RS19455	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Axylo_RS19460	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Axylo_RS19480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Axylo_RS19490	COG3391	amine dehydrogenase activity
Axylo_RS19520	COG1846	Transcriptional regulator
Axylo_RS19530	COG1566	PFAM secretion protein HlyD family protein
Axylo_RS19535	COG2814	Major facilitator Superfamily
Axylo_RS19545	COG0473	3-isopropylmalate dehydrogenase activity
Axylo_RS19550	COG0433	COG0433 Predicted ATPase
Axylo_RS19555	COG0217	transcriptional regulatory protein
Axylo_RS19560	COG0151	Belongs to the GarS family
Axylo_RS19570	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Axylo_RS19575	COG0799	negative regulation of ribosome biogenesis
Axylo_RS19580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Axylo_RS19590	COG1301	dicarboxylic acid transport
Axylo_RS19595	COG4191	Histidine kinase
Axylo_RS19600	COG2204	response regulator
Axylo_RS19635	COG0583	DNA-binding transcription factor activity
Axylo_RS19640	COG0427	acetyl-CoA hydrolase
Axylo_RS19645	COG0583	DNA-binding transcription factor activity
Axylo_RS19650	COG1511	domain protein
Axylo_RS19650	COG3264	Mechanosensitive ion channel
Axylo_RS19710	COG3842	ATPase activity
Axylo_RS19715	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_RS19720	COG1177	transmembrane transport
Axylo_RS19725	COG3938	Belongs to the proline racemase family
Axylo_RS19730	COG0517	IMP dehydrogenase activity
Axylo_RS19760	COG0500	methyltransferase
Axylo_RS19765	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Axylo_RS19785	COG0667	Aldo Keto reductase
Axylo_RS19790	COG2207	Transcriptional regulator
Axylo_RS19800	COG1595	DNA-templated transcription, initiation
Axylo_RS19815	COG2841	Protein conserved in bacteria
Axylo_RS19830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Axylo_RS19835	COG0477	Major facilitator Superfamily
Axylo_RS19845	COG2814	Major facilitator Superfamily
Axylo_RS19850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Axylo_RS19885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Axylo_RS19895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Axylo_RS19900	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Axylo_RS19905	COG1534	Rna-binding protein
Axylo_RS19910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Axylo_RS19915	COG0840	transmembrane signaling receptor activity
Axylo_RS19920	COG2233	PERMEase
Axylo_RS19940	COG3842	ATPase activity
Axylo_RS19950	COG0406	alpha-ribazole phosphatase activity
Axylo_RS19955	COG4221	oxidoreductase activity
Axylo_RS19965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Axylo_RS19970	COG0505	Belongs to the CarA family
Axylo_RS19990	COG0745	RESPONSE REGULATOR receiver
Axylo_RS20005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_RS20015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Axylo_RS20020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS20035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Axylo_RS20040	COG1074	ATP-dependent DNA helicase activity
Axylo_RS20055	COG2070	2-Nitropropane dioxygenase
Axylo_RS20075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS20080	COG1024	Enoyl-CoA hydratase
Axylo_RS20090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_RS20095	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_RS20110	COG1686	Belongs to the peptidase S11 family
Axylo_RS20130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Axylo_RS20135	COG4974	Belongs to the 'phage' integrase family
Axylo_RS20140	COG0583	DNA-binding transcription factor activity
Axylo_RS20145	COG0028	Belongs to the TPP enzyme family
Axylo_RS20170	COG3328	transposase activity
Axylo_RS20200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Axylo_RS20245	COG0028	Belongs to the TPP enzyme family
Axylo_RS20250	COG1126	abc transporter atp-binding protein
Axylo_RS20255	COG0765	amino acid transport
Axylo_RS20265	COG0010	Belongs to the arginase family
Axylo_RS20270	COG1414	Transcriptional regulator
Axylo_RS20275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS20290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Axylo_RS20295	COG1414	Transcriptional regulator
Axylo_RS20300	COG0009	L-threonylcarbamoyladenylate synthase
Axylo_RS20305	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Axylo_RS20310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Axylo_RS20315	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Axylo_RS20325	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Axylo_RS20345	COG1301	dicarboxylic acid transport
Axylo_RS20365	COG3454	Phosphonate metabolism
Axylo_RS20370	COG4778	phosphonate C-P lyase system protein PhnL
Axylo_RS20375	COG4107	phosphonate C-P lyase system protein PhnK
Axylo_RS20380	COG3627	carbon phosphorus lyase activity
Axylo_RS20385	COG3626	phosphonate metabolism
Axylo_RS20390	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
Axylo_RS20395	COG3624	Phosphonate C-P lyase system protein PhnG
Axylo_RS20400	COG2188	Transcriptional regulator
Axylo_RS20405	COG3454	Phosphonate metabolism
Axylo_RS20415	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Axylo_RS20420	COG0583	DNA-binding transcription factor activity
Axylo_RS20440	COG3639	organic phosphonate transmembrane transporter activity
Axylo_RS20445	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Axylo_RS20450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Axylo_RS20460	COG0640	Transcriptional regulator
Axylo_RS20470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Axylo_RS20480	COG0739	heme binding
Axylo_RS20490	COG0521	Mo-molybdopterin cofactor biosynthetic process
Axylo_RS20500	COG0306	phosphate transporter
Axylo_RS20535	COG0625	glutathione transferase activity
Axylo_RS20555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Axylo_RS20560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Axylo_RS20575	COG0126	phosphoglycerate kinase activity
Axylo_RS20580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Axylo_RS20585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Axylo_RS20595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Axylo_RS20600	COG2732	(Barnase) inhibitor
Axylo_RS20610	COG0280	phosphate acetyltransferase
Axylo_RS20610	COG0281	malic enzyme
Axylo_RS20620	COG0436	Aminotransferase
Axylo_RS20630	COG0741	lytic transglycosylase activity
Axylo_RS20635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Axylo_RS20650	COG4575	ribosome binding
Axylo_RS20660	COG1116	anion transmembrane transporter activity
Axylo_RS20665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_RS20670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Axylo_RS20675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Axylo_RS20675	COG1648	precorrin-2 dehydrogenase activity
Axylo_RS20680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Axylo_RS20685	COG2027	D-alanyl-D-alanine carboxypeptidase
Axylo_RS20700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Axylo_RS20710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Axylo_RS20715	COG0343	queuine tRNA-ribosyltransferase activity
Axylo_RS20725	COG3077	Addiction module antitoxin, RelB DinJ family
Axylo_RS20730	COG1862	Preprotein translocase
Axylo_RS20735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Axylo_RS20740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Axylo_RS20750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Axylo_RS20760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Axylo_RS20765	COG1702	phosphate starvation-inducible protein PhoH
Axylo_RS20770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Axylo_RS20775	COG4535	Mg2 and Co2 transporter CorC
Axylo_RS20780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Axylo_RS20785	COG0667	Aldo Keto reductase
Axylo_RS20830	COG0697	spore germination
Axylo_RS20840	COG0678	peroxiredoxin activity
Axylo_RS20850	COG0412	Dienelactone hydrolase
Axylo_RS20860	COG0315	cyclic pyranopterin monophosphate synthase activity
Axylo_RS20870	COG0314	molybdopterin synthase activity
Axylo_RS20875	COG0521	Mo-molybdopterin cofactor biosynthetic process
Axylo_RS20880	COG0303	'Molybdopterin
Axylo_RS20885	COG0746	molybdenum cofactor guanylyltransferase activity
Axylo_RS20890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Axylo_RS20910	COG3383	formate dehydrogenase (NAD+) activity
Axylo_RS20915	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Axylo_RS20925	COG2223	nitrite transmembrane transporter activity
Axylo_RS20950	COG0583	DNA-binding transcription factor activity
Axylo_RS20955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Axylo_RS20990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Axylo_RS21005	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS21025	COG2828	Protein conserved in bacteria
Axylo_RS21030	COG0583	DNA-binding transcription factor activity
Axylo_RS21035	COG0456	acetyltransferase
Axylo_RS21045	COG1595	DNA-templated transcription, initiation
Axylo_RS21080	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS21105	COG4774	siderophore transport
Axylo_RS21120	COG0671	phosphoesterase, PA-phosphatase related
Axylo_RS21135	COG1666	GTP binding
Axylo_RS21140	COG1120	ATPase activity
Axylo_RS21145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_RS21150	COG4558	Periplasmic binding protein
Axylo_RS21155	COG3720	iron ion transport
Axylo_RS21165	COG3712	iron ion homeostasis
Axylo_RS21170	COG1595	DNA-templated transcription, initiation
Axylo_RS21200	COG2378	regulation of single-species biofilm formation
Axylo_RS21230	COG1113	amino acid transport
Axylo_RS21240	COG1522	sequence-specific DNA binding
Axylo_RS21245	COG1272	protein, Hemolysin III
Axylo_RS21250	COG3191	aminopeptidase activity
Axylo_RS21255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS21260	COG0765	amino acid transport
Axylo_RS21290	COG1999	signal sequence binding
Axylo_RS21310	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Axylo_RS21320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Axylo_RS21325	COG1845	cytochrome c oxidase, subunit III
Axylo_RS21330	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Axylo_RS21355	COG4772	TonB-dependent receptor
Axylo_RS21375	COG0280	phosphate acetyltransferase
Axylo_RS21375	COG0281	malic enzyme
Axylo_RS21390	COG0697	spore germination
Axylo_RS21425	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS21430	COG0583	DNA-binding transcription factor activity
Axylo_RS21445	COG0456	acetyltransferase
Axylo_RS21450	COG1396	sequence-specific DNA binding
Axylo_RS21455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Axylo_RS21465	COG3145	DNA-N1-methyladenine dioxygenase activity
Axylo_RS21470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Axylo_RS21485	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Axylo_RS21490	COG1285	pathogenesis
Axylo_RS21495	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS21500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Axylo_RS21505	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Axylo_RS21515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Axylo_RS21530	COG3712	iron ion homeostasis
Axylo_RS21545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Axylo_RS21550	COG0330	HflC and HflK could
Axylo_RS21575	COG2807	transmembrane transport
Axylo_RS21580	COG2207	Transcriptional regulator
Axylo_RS21585	COG4106	trans-aconitate 2-methyltransferase activity
Axylo_RS21600	COG0583	DNA-binding transcription factor activity
Axylo_RS21640	COG0477	Major facilitator Superfamily
Axylo_RS21645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Axylo_RS21650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Axylo_RS21655	COG1845	cytochrome c oxidase, subunit III
Axylo_RS21660	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Axylo_RS21670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS21675	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS21685	COG2814	Major facilitator Superfamily
Axylo_RS21695	COG0625	glutathione transferase activity
Axylo_RS21720	COG2197	response regulator
Axylo_RS21745	COG3707	response regulator
Axylo_RS21750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Axylo_RS21750	COG2146	nitrite reductase [NAD(P)H] activity
Axylo_RS21755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Axylo_RS21755	COG2146	nitrite reductase [NAD(P)H] activity
Axylo_RS21760	COG0243	molybdopterin cofactor binding
Axylo_RS21765	COG0667	Aldo Keto reductase
Axylo_RS21770	COG0656	L-ascorbic acid biosynthetic process
Axylo_RS21775	COG0583	DNA-binding transcription factor activity
Axylo_RS21780	COG0023	Translation Initiation Factor
Axylo_RS21790	COG0454	-acetyltransferase
Axylo_RS21790	COG0456	acetyltransferase
Axylo_RS21815	COG0840	transmembrane signaling receptor activity
Axylo_RS21820	COG2199	diguanylate cyclase activity
Axylo_RS21820	COG2203	Gaf domain
Axylo_RS21825	COG0640	Transcriptional regulator
Axylo_RS21835	COG0740	serine-type endopeptidase activity
Axylo_RS21860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_RS21870	COG0596	Alpha beta hydrolase
Axylo_RS21915	COG0028	Belongs to the TPP enzyme family
Axylo_RS21950	COG4771	TonB-dependent receptor
Axylo_RS21960	COG2375	cellular response to nickel ion
Axylo_RS21960	COG1132	(ABC) transporter
Axylo_RS21965	COG1132	(ABC) transporter
Axylo_RS21965	COG2375	cellular response to nickel ion
Axylo_RS21975	COG1201	RNA secondary structure unwinding
Axylo_RS21980	COG1793	dna ligase
Axylo_RS21995	COG0798	PFAM Bile acid sodium symporter
Axylo_RS22000	COG1393	Belongs to the ArsC family
Axylo_RS22005	COG0431	NADPH-dependent FMN reductase
Axylo_RS22025	COG0697	spore germination
Axylo_RS22060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Axylo_RS22100	COG0745	RESPONSE REGULATOR receiver
Axylo_RS22110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Axylo_RS22135	COG0793	Belongs to the peptidase S41A family
Axylo_RS22180	COG2200	EAL domain
Axylo_RS22205	COG4191	Histidine kinase
Axylo_RS22220	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS22270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Axylo_RS22275	COG0459	protein refolding
Axylo_RS22280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Axylo_RS22285	COG0583	DNA-binding transcription factor activity
Axylo_RS22305	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_RS22315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_RS22330	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS22330	COG3321	synthase
Axylo_RS22330	COG0604	alcohol dehydrogenase
Axylo_RS22335	COG3842	ATPase activity
Axylo_RS22340	COG2072	flavoprotein involved in K transport
Axylo_RS22350	COG1846	Transcriptional regulator
Axylo_RS22370	COG1917	Cupin 2, conserved barrel domain protein
Axylo_RS22395	COG1137	ATPase activity
Axylo_RS22405	COG0246	Mannitol dehydrogenase
Axylo_RS22410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Axylo_RS22415	COG1252	NADH dehydrogenase
Axylo_RS22420	COG0284	orotidine-5'-phosphate decarboxylase activity
Axylo_RS22425	COG1546	Belongs to the CinA family
Axylo_RS22430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Axylo_RS22435	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Axylo_RS22440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Axylo_RS22445	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Axylo_RS22470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Axylo_RS22475	COG3639	organic phosphonate transmembrane transporter activity
Axylo_RS22480	COG3639	organic phosphonate transmembrane transporter activity
Axylo_RS22495	COG0742	ribosomal rna small subunit methyltransferase
Axylo_RS22500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Axylo_RS22505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Axylo_RS22510	COG3135	benzoate transporter
Axylo_RS22525	COG2814	Major facilitator Superfamily
Axylo_RS22535	COG0488	(ABC) transporter
Axylo_RS22550	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Axylo_RS22555	COG4804	nuclease activity
Axylo_RS22570	COG0012	GTP binding
Axylo_RS22580	COG0193	aminoacyl-tRNA hydrolase activity
Axylo_RS22600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Axylo_RS22605	COG0840	transmembrane signaling receptor activity
Axylo_RS22620	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Axylo_RS22645	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Axylo_RS22655	COG0204	Acyl-transferase
Axylo_RS22660	COG1368	sulfuric ester hydrolase activity
Axylo_RS22665	COG2186	Transcriptional regulator
Axylo_RS22670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_RS22680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_RS22690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Axylo_RS22690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Axylo_RS22700	COG2205	protein histidine kinase activity
Axylo_RS22705	COG0745	RESPONSE REGULATOR receiver
Axylo_RS22710	COG0277	FAD linked oxidase domain protein
Axylo_RS22725	COG0166	Belongs to the GPI family
Axylo_RS22730	COG0405	Gamma-glutamyltransferase
Axylo_RS22740	COG0438	transferase activity, transferring glycosyl groups
Axylo_RS22745	COG0438	transferase activity, transferring glycosyl groups
Axylo_RS22755	COG0438	transferase activity, transferring glycosyl groups
Axylo_RS22770	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Axylo_RS22775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Axylo_RS22780	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
Axylo_RS22805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS22810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Axylo_RS22825	COG0747	negative chemotaxis
Axylo_RS22830	COG0601	transmembrane transport
Axylo_RS22835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS22840	COG4172	Belongs to the ABC transporter superfamily
Axylo_RS22845	COG0154	amidase activity
Axylo_RS22860	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Axylo_RS22860	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Axylo_RS22865	COG0509	glycine decarboxylation via glycine cleavage system
Axylo_RS22870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Axylo_RS22885	COG2081	HI0933 family
Axylo_RS22905	COG3706	GGDEF domain
Axylo_RS22915	COG0717	Belongs to the dCTP deaminase family
Axylo_RS22930	COG0489	protein tyrosine kinase activity
Axylo_RS22940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Axylo_RS22940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Axylo_RS22945	COG1054	Belongs to the UPF0176 family
Axylo_RS22970	COG0745	RESPONSE REGULATOR receiver
Axylo_RS22975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Axylo_RS23000	COG2200	EAL domain
Axylo_RS23010	COG3243	poly(R)-hydroxyalkanoic acid synthase
Axylo_RS23020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_RS23025	COG1129	ABC transporter
Axylo_RS23025	COG0842	Transport permease protein
Axylo_RS23030	COG0842	Transport permease protein
Axylo_RS23040	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS23045	COG1271	oxidase subunit
Axylo_RS23050	COG1294	oxidase, subunit
Axylo_RS23055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS23090	COG3258	Cytochrome c
Axylo_RS23100	COG0625	glutathione transferase activity
Axylo_RS23120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Axylo_RS23160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Axylo_RS23175	COG2828	Protein conserved in bacteria
Axylo_RS23185	COG0165	Argininosuccinate lyase
Axylo_RS23190	COG2205	protein histidine kinase activity
Axylo_RS23195	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS23200	COG3246	L-lysine catabolic process to acetate
Axylo_RS23220	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Axylo_RS23250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_RS23255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_RS23260	COG0583	DNA-binding transcription factor activity
Axylo_RS23265	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Axylo_RS23280	COG1652	LysM domain
Axylo_RS23285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Axylo_RS23290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Axylo_RS23305	COG0625	glutathione transferase activity
Axylo_RS23320	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_RS23360	COG3550	peptidyl-serine autophosphorylation
Axylo_RS23380	COG1414	Transcriptional regulator
Axylo_RS23390	COG0800	Aldolase
Axylo_RS23395	COG4948	Mandelate Racemase Muconate Lactonizing
Axylo_RS23400	COG2271	Major facilitator Superfamily
Axylo_RS23405	COG1131	(ABC) transporter
Axylo_RS23425	COG2814	Major facilitator Superfamily
Axylo_RS23435	COG1396	sequence-specific DNA binding
Axylo_RS23440	COG0326	Molecular chaperone. Has ATPase activity
Axylo_RS23450	COG2233	PERMEase
Axylo_RS23485	COG4372	Transposase
Axylo_RS23495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Axylo_RS23545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Axylo_RS23560	COG0071	Belongs to the small heat shock protein (HSP20) family
Axylo_RS23600	COG4638	Rieske (2fe-2S)
Axylo_RS23650	COG3657	addiction module killer protein
Axylo_RS23665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS23670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_RS23685	COG1172	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS23690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Axylo_RS23695	COG3246	L-lysine catabolic process to acetate
Axylo_RS23710	COG0583	DNA-binding transcription factor activity
Axylo_RS23815	COG0745	RESPONSE REGULATOR receiver
Axylo_RS23840	COG0583	DNA-binding transcription factor activity
Axylo_RS23850	COG1695	Transcriptional regulator
Axylo_RS23865	COG0477	Major facilitator Superfamily
Axylo_RS23880	COG0277	FAD linked oxidase domain protein
Axylo_RS23890	COG3842	ATPase activity
Axylo_RS23895	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_RS23915	COG0628	permease
Axylo_RS23920	COG0583	DNA-binding transcription factor activity
Axylo_RS23925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_RS23975	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
Axylo_RS23985	COG2186	Transcriptional regulator
Axylo_RS23995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Axylo_RS24020	COG0410	ABC transporter
Axylo_RS24025	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS24030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Axylo_RS24040	COG0508	dehydrogenase complex catalyzes the overall conversion of
Axylo_RS24045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Axylo_RS24050	COG0583	DNA-binding transcription factor activity
Axylo_RS24055	COG0129	dihydroxy-acid dehydratase activity
Axylo_RS24065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_RS24070	COG0583	DNA-binding transcription factor activity
Axylo_RS24085	COG2200	EAL domain
Axylo_RS24090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Axylo_RS24095	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Axylo_RS24100	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_RS24105	COG2031	fatty acid transporter
Axylo_RS24110	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS24115	COG1414	Transcriptional regulator
Axylo_RS24125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Axylo_RS24130	COG4829	muconolactone delta-isomerase
Axylo_RS24140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_RS24160	COG0288	reversible hydration of carbon dioxide
Axylo_RS24170	COG2801	Transposase and inactivated derivatives
Axylo_RS24175	COG1802	Transcriptional regulator
Axylo_RS24180	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS24190	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_RS24210	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS24220	COG1053	succinate dehydrogenase
Axylo_RS24225	COG0625	glutathione transferase activity
Axylo_RS24240	COG0583	DNA-binding transcription factor activity
Axylo_RS24250	COG0583	DNA-binding transcription factor activity
Axylo_RS24255	COG0477	Major facilitator Superfamily
Axylo_RS24280	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_RS24300	COG1464	Belongs to the NlpA lipoprotein family
Axylo_RS24315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Axylo_RS24320	COG2890	protein-(glutamine-N5) methyltransferase activity
Axylo_RS24325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Axylo_RS24340	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS24345	COG1522	sequence-specific DNA binding
Axylo_RS24365	COG3622	Belongs to the hyi family
Axylo_RS24390	COG2186	Transcriptional regulator
Axylo_RS24395	COG3395	kinase activity
Axylo_RS24400	COG2084	Dehydrogenase
Axylo_RS24405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_RS24410	COG3622	Belongs to the hyi family
Axylo_RS24415	COG0235	Class ii aldolase
Axylo_RS24470	COG0142	geranyltranstransferase activity
Axylo_RS24475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Axylo_RS24480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Axylo_RS24485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Axylo_RS24490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Axylo_RS24505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Axylo_RS24505	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Axylo_RS24510	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Axylo_RS24520	COG2186	Transcriptional regulator
Axylo_RS24525	COG5002	protein histidine kinase activity
Axylo_RS24525	COG3447	MASE1 domain protein
Axylo_RS24525	COG5001	Diguanylate cyclase
Axylo_RS24530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Axylo_RS24535	COG0793	Belongs to the peptidase S41A family
Axylo_RS24540	COG4942	peptidase
Axylo_RS24545	COG0588	phosphoglycerate mutase activity
Axylo_RS24550	COG1054	Belongs to the UPF0176 family
Axylo_RS24555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Axylo_RS24560	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Axylo_RS24565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Axylo_RS24585	COG2226	methyltransferase
Axylo_RS24590	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Axylo_RS24595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Axylo_RS24600	COG0569	domain protein
Axylo_RS24605	COG2204	response regulator
Axylo_RS24610	COG5000	phosphorelay sensor kinase activity
Axylo_RS24620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Axylo_RS24620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Axylo_RS24625	COG1280	lysine exporter protein (LysE YggA)
Axylo_RS24630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Axylo_RS24640	COG1733	regulation of RNA biosynthetic process
Axylo_RS24660	COG0546	phosphoglycolate phosphatase activity
Axylo_RS24670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Axylo_RS24675	COG0242	peptide deformylase activity
Axylo_RS24680	COG0758	DNA mediated transformation
Axylo_RS24695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_RS24700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS24705	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Axylo_RS24710	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS24725	COG1238	metal cluster binding
Axylo_RS24730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Axylo_RS24735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_RS24750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Axylo_RS24755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Axylo_RS24760	COG4988	ABC transporter
Axylo_RS24770	COG1294	oxidase, subunit
Axylo_RS24785	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Axylo_RS24795	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Axylo_RS24810	COG1137	ATPase activity
Axylo_RS24815	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Axylo_RS24825	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Axylo_RS24830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS24845	COG1660	Displays ATPase and GTPase activities
Axylo_RS24855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Axylo_RS24865	COG0792	nuclease activity
Axylo_RS24870	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Axylo_RS24880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_RS24890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Axylo_RS24900	COG1309	transcriptional regulator
Axylo_RS24905	COG0471	metal ion transport
Axylo_RS24910	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Axylo_RS24915	COG0772	Belongs to the SEDS family
Axylo_RS24920	COG0768	penicillin binding
Axylo_RS24930	COG1792	Involved in formation and maintenance of cell shape
Axylo_RS24935	COG1077	Cell shape determining protein MreB Mrl
Axylo_RS24940	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Axylo_RS24945	COG0154	amidase activity
Axylo_RS24950	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Axylo_RS24965	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Axylo_RS24970	COG0708	Exodeoxyribonuclease III
Axylo_RS24975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Axylo_RS24985	COG0583	DNA-binding transcription factor activity
Axylo_RS25000	COG0583	DNA-binding transcription factor activity
Axylo_RS25030	COG1764	response to oxidative stress
Axylo_RS25035	COG1846	Transcriptional regulator
Axylo_RS25095	COG0640	Transcriptional regulator
Axylo_RS25120	COG0297	glycogen (starch) synthase activity
Axylo_RS25130	COG3189	MarR family transcriptional regulator
Axylo_RS25150	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_RS25155	COG0352	thiamine-phosphate diphosphorylase activity
Axylo_RS25155	COG0351	phosphomethylpyrimidine kinase
Axylo_RS25155	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Axylo_RS25170	COG3063	Type IV pilus biogenesis stability protein PilW
Axylo_RS25185	COG3210	domain, Protein
Axylo_RS25195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Axylo_RS25200	COG0513	Belongs to the DEAD box helicase family
Axylo_RS25210	COG0617	tRNA 3'-terminal CCA addition
Axylo_RS25220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Axylo_RS25225	COG2308	Evidence 4 Homologs of previously reported genes of
Axylo_RS25235	COG1305	Transglutaminase-like
Axylo_RS25255	COG1950	PFAM Membrane protein of
Axylo_RS25260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Axylo_RS25265	COG0438	transferase activity, transferring glycosyl groups
Axylo_RS25280	COG0066	3-isopropylmalate dehydratase activity
Axylo_RS25290	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_RS25295	COG0583	DNA-binding transcription factor activity
Axylo_RS25300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Axylo_RS25335	COG0477	Major facilitator Superfamily
Axylo_RS25340	COG0154	amidase activity
Axylo_RS25345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Axylo_RS25355	COG1560	Kdo2-lipid A biosynthetic process
Axylo_RS25360	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Axylo_RS25370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Axylo_RS25375	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Axylo_RS25400	COG0735	belongs to the Fur family
Axylo_RS25405	COG0523	cobalamin synthesis protein
Axylo_RS25415	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Axylo_RS25420	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Axylo_RS25430	COG2096	Adenosyltransferase
Axylo_RS25445	COG1091	dTDP-4-dehydrorhamnose reductase activity
Axylo_RS25450	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Axylo_RS25460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Axylo_RS25485	COG0438	transferase activity, transferring glycosyl groups
Axylo_RS25505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Axylo_RS25510	COG1609	Transcriptional regulator
Axylo_RS25520	COG0321	lipoyl(octanoyl) transferase activity
Axylo_RS25525	COG2921	Belongs to the UPF0250 family
Axylo_RS25535	COG1686	Belongs to the peptidase S11 family
Axylo_RS25560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Axylo_RS25570	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Axylo_RS25580	COG0859	PFAM glycosyl transferase family 9
Axylo_RS25585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Axylo_RS25595	COG2814	Major facilitator Superfamily
Axylo_RS25610	COG3568	Endonuclease Exonuclease Phosphatase
Axylo_RS25615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Axylo_RS25640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Axylo_RS25655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_RS25660	COG1956	GAF domain-containing protein
Axylo_RS25665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_RS25690	COG2186	Transcriptional regulator
Axylo_RS25725	COG2226	methyltransferase
Axylo_RS25735	COG2814	Major facilitator Superfamily
Axylo_RS25745	COG0625	glutathione transferase activity
Axylo_RS25750	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Axylo_RS25755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Axylo_RS25760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Axylo_RS25770	COG1965	Belongs to the frataxin family
Axylo_RS25780	COG0019	diaminopimelate decarboxylase activity
Axylo_RS25785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Axylo_RS25790	COG1333	cytochrome c biogenesis protein
Axylo_RS25800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Axylo_RS25815	COG4232	protein-disulfide reductase activity
Axylo_RS25820	COG1324	tolerance protein
Axylo_RS25830	COG0203	ribosomal protein L17
Axylo_RS25835	COG0202	RNA polymerase activity
Axylo_RS25840	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Axylo_RS25845	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Axylo_RS25850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Axylo_RS25855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Axylo_RS25860	COG0201	protein transport
Axylo_RS25865	COG0200	Binds to the 23S rRNA
Axylo_RS25870	COG1841	ribosomal large subunit assembly
Axylo_RS25875	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Axylo_RS25880	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Axylo_RS25885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Axylo_RS25890	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Axylo_RS25895	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Axylo_RS25900	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Axylo_RS25905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Axylo_RS25910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Axylo_RS25930	COG2207	Transcriptional regulator
Axylo_RS25935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_RS25970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Axylo_RS25975	COG0255	Belongs to the universal ribosomal protein uL29 family
Axylo_RS25980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Axylo_RS25985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Axylo_RS25990	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Axylo_RS25995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Axylo_RS26000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Axylo_RS26005	COG0089	rRNA binding
Axylo_RS26015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Axylo_RS26020	COG0051	transcription antitermination factor activity, RNA binding
Axylo_RS26025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Axylo_RS26030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Axylo_RS26035	COG0049	tRNA binding
Axylo_RS26040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Axylo_RS26045	COG0745	RESPONSE REGULATOR receiver
Axylo_RS26060	COG5002	protein histidine kinase activity
Axylo_RS26075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Axylo_RS26080	COG0085	RNA polymerase activity
Axylo_RS26085	COG0222	ribosome binding
Axylo_RS26090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Axylo_RS26095	COG0081	regulation of translation
Axylo_RS26100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Axylo_RS26110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Axylo_RS26120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Axylo_RS26160	COG1840	ABC-type Fe3 transport system, periplasmic component
Axylo_RS26165	COG3842	ATPase activity
Axylo_RS26175	COG1349	DNA-binding transcription factor activity
Axylo_RS26200	COG0583	DNA-binding transcription factor activity
Axylo_RS26205	COG0252	asparaginase activity
Axylo_RS26210	COG1475	DNA binding
Axylo_RS26220	COG1192	Involved in chromosome partitioning
Axylo_RS26225	COG0357	Ribosomal RNA small subunit methyltransferase G
Axylo_RS26230	COG0445	tRNA wobble uridine modification
Axylo_RS26235	COG1278	Cold shock
Axylo_RS26240	COG3180	Ammonia monooxygenase
Axylo_RS26245	COG0436	Aminotransferase
Axylo_RS26275	COG0038	chloride channel
Axylo_RS26285	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Axylo_RS26295	COG0601	transmembrane transport
Axylo_RS26300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_RS26305	COG0444	Belongs to the ABC transporter superfamily
Axylo_RS26310	COG4608	Belongs to the ABC transporter superfamily
Axylo_RS26315	COG1473	amidohydrolase
Axylo_RS26320	COG2175	clavaminate synthase activity
Axylo_RS26335	COG0753	catalase activity
Axylo_RS26345	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Axylo_RS26350	COG0594	ribonuclease P activity
Axylo_RS26355	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Axylo_RS26385	COG3210	domain, Protein
Axylo_RS26385	COG3468	outer membrane autotransporter barrel domain protein
Axylo_RS26395	COG1686	Belongs to the peptidase S11 family
Axylo_RS26415	COG2814	Major facilitator Superfamily
Axylo_RS26490	COG0802	atpase or kinase
Axylo_RS26625	COG0840	transmembrane signaling receptor activity
Axylo_RS26735	COG0589	response to stress
Axylo_RS26915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Axylo_RS26920	COG0257	Belongs to the bacterial ribosomal protein bL36 family