locus-tag	class	description
IUJ48_RS00015	COG1131	(ABC) transporter
IUJ48_RS00020	COG2271	Major facilitator Superfamily
IUJ48_RS00025	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_RS00030	COG0800	Aldolase
IUJ48_RS00040	COG1414	Transcriptional regulator
IUJ48_RS00060	COG3550	peptidyl-serine autophosphorylation
IUJ48_RS00095	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_RS00130	COG0625	glutathione transferase activity
IUJ48_RS00145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ48_RS00150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IUJ48_RS00155	COG1652	LysM domain
IUJ48_RS00175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IUJ48_RS00180	COG0583	DNA-binding transcription factor activity
IUJ48_RS00185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS00190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ48_RS00235	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_RS00240	COG0372	Belongs to the citrate synthase family
IUJ48_RS00245	COG0154	amidase activity
IUJ48_RS00250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ48_RS00255	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IUJ48_RS00270	COG3246	L-lysine catabolic process to acetate
IUJ48_RS00275	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS00285	COG0477	Major facilitator Superfamily
IUJ48_RS00315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_RS00325	COG2205	protein histidine kinase activity
IUJ48_RS00330	COG0165	Argininosuccinate lyase
IUJ48_RS00340	COG3712	iron ion homeostasis
IUJ48_RS00345	COG1595	DNA-templated transcription, initiation
IUJ48_RS00365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IUJ48_RS00390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IUJ48_RS00405	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IUJ48_RS00415	COG1234	tRNA 3'-trailer cleavage
IUJ48_RS00425	COG0625	glutathione transferase activity
IUJ48_RS00435	COG3258	Cytochrome c
IUJ48_RS00470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS00480	COG1294	oxidase, subunit
IUJ48_RS00485	COG1271	oxidase subunit
IUJ48_RS00490	COG0697	spore germination
IUJ48_RS00495	COG0583	DNA-binding transcription factor activity
IUJ48_RS00500	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS00510	COG0842	Transport permease protein
IUJ48_RS00515	COG1129	ABC transporter
IUJ48_RS00515	COG0842	Transport permease protein
IUJ48_RS00520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_RS00540	COG2200	EAL domain
IUJ48_RS00560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ48_RS00575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IUJ48_RS00575	COG2755	lipolytic protein G-D-S-L family
IUJ48_RS00590	COG1054	Belongs to the UPF0176 family
IUJ48_RS00595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ48_RS00595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ48_RS00605	COG0489	protein tyrosine kinase activity
IUJ48_RS00620	COG0717	Belongs to the dCTP deaminase family
IUJ48_RS00630	COG3706	GGDEF domain
IUJ48_RS00650	COG2081	HI0933 family
IUJ48_RS00665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IUJ48_RS00670	COG0509	glycine decarboxylation via glycine cleavage system
IUJ48_RS00675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IUJ48_RS00675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IUJ48_RS00715	COG0154	amidase activity
IUJ48_RS00720	COG4172	Belongs to the ABC transporter superfamily
IUJ48_RS00725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS00730	COG0601	transmembrane transport
IUJ48_RS00735	COG0747	negative chemotaxis
IUJ48_RS00750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ48_RS00755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS00785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IUJ48_RS00790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IUJ48_RS00815	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS00820	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS00825	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS00830	COG0405	Gamma-glutamyltransferase
IUJ48_RS00835	COG0166	Belongs to the GPI family
IUJ48_RS00850	COG0277	FAD linked oxidase domain protein
IUJ48_RS00855	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS00870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_RS00870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_RS00880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_RS00890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_RS00895	COG2186	Transcriptional regulator
IUJ48_RS00900	COG1368	sulfuric ester hydrolase activity
IUJ48_RS00905	COG0204	Acyl-transferase
IUJ48_RS00915	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IUJ48_RS00940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUJ48_RS00955	COG0840	transmembrane signaling receptor activity
IUJ48_RS00960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IUJ48_RS00980	COG0193	aminoacyl-tRNA hydrolase activity
IUJ48_RS00990	COG0012	GTP binding
IUJ48_RS00995	COG0582	viral genome integration into host DNA
IUJ48_RS01000	COG0582	viral genome integration into host DNA
IUJ48_RS01010	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IUJ48_RS01015	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IUJ48_RS01045	COG4804	nuclease activity
IUJ48_RS01050	COG4773	Receptor
IUJ48_RS01055	COG0488	(ABC) transporter
IUJ48_RS01070	COG2814	Major facilitator Superfamily
IUJ48_RS01085	COG3135	benzoate transporter
IUJ48_RS01090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ48_RS01095	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IUJ48_RS01100	COG0742	ribosomal rna small subunit methyltransferase
IUJ48_RS01120	COG3639	organic phosphonate transmembrane transporter activity
IUJ48_RS01125	COG3639	organic phosphonate transmembrane transporter activity
IUJ48_RS01130	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IUJ48_RS01155	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IUJ48_RS01160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ48_RS01175	COG1546	Belongs to the CinA family
IUJ48_RS01180	COG0284	orotidine-5'-phosphate decarboxylase activity
IUJ48_RS01185	COG1252	NADH dehydrogenase
IUJ48_RS01190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IUJ48_RS01195	COG0246	Mannitol dehydrogenase
IUJ48_RS01205	COG1137	ATPase activity
IUJ48_RS01230	COG1917	Cupin 2, conserved barrel domain protein
IUJ48_RS01250	COG1846	Transcriptional regulator
IUJ48_RS01260	COG0459	protein refolding
IUJ48_RS01265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IUJ48_RS01295	COG1595	DNA-templated transcription, initiation
IUJ48_RS01340	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS01355	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_RS01360	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS01365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_RS01370	COG0583	DNA-binding transcription factor activity
IUJ48_RS01395	COG0583	DNA-binding transcription factor activity
IUJ48_RS01400	COG0583	DNA-binding transcription factor activity
IUJ48_RS01405	COG0436	Aminotransferase
IUJ48_RS01415	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS01425	COG0697	spore germination
IUJ48_RS01430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS01440	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS01485	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IUJ48_RS01485	COG1793	dna ligase
IUJ48_RS01490	COG1793	dna ligase
IUJ48_RS01500	COG1201	RNA secondary structure unwinding
IUJ48_RS01510	COG1132	(ABC) transporter
IUJ48_RS01530	COG1230	cation diffusion facilitator family transporter
IUJ48_RS01550	COG0028	Belongs to the TPP enzyme family
IUJ48_RS01585	COG0583	DNA-binding transcription factor activity
IUJ48_RS01590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_RS01600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ48_RS01610	COG0596	Alpha beta hydrolase
IUJ48_RS01620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_RS01650	COG2814	Major facilitator Superfamily
IUJ48_RS01655	COG0740	serine-type endopeptidase activity
IUJ48_RS01665	COG0640	Transcriptional regulator
IUJ48_RS01670	COG2203	Gaf domain
IUJ48_RS01670	COG2199	diguanylate cyclase activity
IUJ48_RS01675	COG0840	transmembrane signaling receptor activity
IUJ48_RS01690	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_RS01695	COG0583	DNA-binding transcription factor activity
IUJ48_RS01700	COG0454	-acetyltransferase
IUJ48_RS01700	COG0456	acetyltransferase
IUJ48_RS01710	COG0023	Translation Initiation Factor
IUJ48_RS01715	COG0583	DNA-binding transcription factor activity
IUJ48_RS01720	COG0656	L-ascorbic acid biosynthetic process
IUJ48_RS01735	COG0667	Aldo Keto reductase
IUJ48_RS01745	COG0243	molybdopterin cofactor binding
IUJ48_RS01750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ48_RS01750	COG2146	nitrite reductase [NAD(P)H] activity
IUJ48_RS01755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ48_RS01755	COG2146	nitrite reductase [NAD(P)H] activity
IUJ48_RS01760	COG3707	response regulator
IUJ48_RS01815	COG0625	glutathione transferase activity
IUJ48_RS01830	COG2814	Major facilitator Superfamily
IUJ48_RS01840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS01845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS01850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS01860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUJ48_RS01865	COG1845	cytochrome c oxidase, subunit III
IUJ48_RS01870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ48_RS01875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IUJ48_RS01880	COG0477	Major facilitator Superfamily
IUJ48_RS01885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS01890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ48_RS01915	COG3712	iron ion homeostasis
IUJ48_RS01945	COG0583	DNA-binding transcription factor activity
IUJ48_RS01960	COG4106	trans-aconitate 2-methyltransferase activity
IUJ48_RS01965	COG2207	Transcriptional regulator
IUJ48_RS01970	COG2807	transmembrane transport
IUJ48_RS01995	COG0330	HflC and HflK could
IUJ48_RS02000	COG5001	Diguanylate cyclase
IUJ48_RS02020	COG4773	Receptor
IUJ48_RS02025	COG4221	oxidoreductase activity
IUJ48_RS02035	COG1595	DNA-templated transcription, initiation
IUJ48_RS02040	COG3712	iron ion homeostasis
IUJ48_RS02055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IUJ48_RS02070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ48_RS02075	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS02080	COG1285	pathogenesis
IUJ48_RS02085	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IUJ48_RS02125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ48_RS02130	COG1396	sequence-specific DNA binding
IUJ48_RS02150	COG0583	DNA-binding transcription factor activity
IUJ48_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS02195	COG0697	spore germination
IUJ48_RS02210	COG0281	malic enzyme
IUJ48_RS02210	COG0280	phosphate acetyltransferase
IUJ48_RS02230	COG4772	TonB-dependent receptor
IUJ48_RS02240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUJ48_RS02245	COG1845	cytochrome c oxidase, subunit III
IUJ48_RS02250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ48_RS02260	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IUJ48_RS02280	COG1999	signal sequence binding
IUJ48_RS02300	COG4942	peptidase
IUJ48_RS02305	COG1126	abc transporter atp-binding protein
IUJ48_RS02310	COG0765	amino acid transport
IUJ48_RS02315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS02320	COG3191	aminopeptidase activity
IUJ48_RS02325	COG1272	protein, Hemolysin III
IUJ48_RS02330	COG1522	sequence-specific DNA binding
IUJ48_RS02340	COG1113	amino acid transport
IUJ48_RS02345	COG0583	DNA-binding transcription factor activity
IUJ48_RS02370	COG2378	regulation of single-species biofilm formation
IUJ48_RS02385	COG1595	DNA-templated transcription, initiation
IUJ48_RS02390	COG3712	iron ion homeostasis
IUJ48_RS02400	COG3720	iron ion transport
IUJ48_RS02405	COG4558	Periplasmic binding protein
IUJ48_RS02410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS02415	COG1120	ATPase activity
IUJ48_RS02420	COG1666	GTP binding
IUJ48_RS02435	COG0671	phosphoesterase, PA-phosphatase related
IUJ48_RS02440	COG4585	Histidine kinase
IUJ48_RS02460	COG4774	siderophore transport
IUJ48_RS02485	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS02525	COG0456	acetyltransferase
IUJ48_RS02530	COG0583	DNA-binding transcription factor activity
IUJ48_RS02535	COG2828	Protein conserved in bacteria
IUJ48_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS02570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ48_RS02605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IUJ48_RS02610	COG0583	DNA-binding transcription factor activity
IUJ48_RS02635	COG2223	nitrite transmembrane transporter activity
IUJ48_RS02645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IUJ48_RS02650	COG3383	formate dehydrogenase (NAD+) activity
IUJ48_RS02670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IUJ48_RS02680	COG0303	'Molybdopterin
IUJ48_RS02685	COG0521	Mo-molybdopterin cofactor biosynthetic process
IUJ48_RS02690	COG0314	molybdopterin synthase activity
IUJ48_RS02700	COG0315	cyclic pyranopterin monophosphate synthase activity
IUJ48_RS02710	COG0412	Dienelactone hydrolase
IUJ48_RS02720	COG0678	peroxiredoxin activity
IUJ48_RS02730	COG0697	spore germination
IUJ48_RS02775	COG0667	Aldo Keto reductase
IUJ48_RS02780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IUJ48_RS02785	COG4535	Mg2 and Co2 transporter CorC
IUJ48_RS02790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IUJ48_RS02795	COG1702	phosphate starvation-inducible protein PhoH
IUJ48_RS02800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IUJ48_RS02810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IUJ48_RS02830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ48_RS02835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ48_RS02840	COG1862	Preprotein translocase
IUJ48_RS02845	COG3077	Addiction module antitoxin, RelB DinJ family
IUJ48_RS02855	COG0343	queuine tRNA-ribosyltransferase activity
IUJ48_RS02860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IUJ48_RS02870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_RS02885	COG2027	D-alanyl-D-alanine carboxypeptidase
IUJ48_RS02890	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IUJ48_RS02895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IUJ48_RS02895	COG1648	precorrin-2 dehydrogenase activity
IUJ48_RS02900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_RS02905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS02910	COG1116	anion transmembrane transporter activity
IUJ48_RS02920	COG4575	ribosome binding
IUJ48_RS02935	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IUJ48_RS02940	COG0741	lytic transglycosylase activity
IUJ48_RS02955	COG0436	Aminotransferase
IUJ48_RS02965	COG0280	phosphate acetyltransferase
IUJ48_RS02965	COG0281	malic enzyme
IUJ48_RS02975	COG2732	(Barnase) inhibitor
IUJ48_RS02980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IUJ48_RS02990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IUJ48_RS02995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUJ48_RS03000	COG0126	phosphoglycerate kinase activity
IUJ48_RS03015	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IUJ48_RS03020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IUJ48_RS03040	COG0625	glutathione transferase activity
IUJ48_RS03075	COG0306	phosphate transporter
IUJ48_RS03085	COG0521	Mo-molybdopterin cofactor biosynthetic process
IUJ48_RS03095	COG0739	heme binding
IUJ48_RS03105	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IUJ48_RS03115	COG0640	Transcriptional regulator
IUJ48_RS03125	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IUJ48_RS03130	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IUJ48_RS03135	COG3639	organic phosphonate transmembrane transporter activity
IUJ48_RS03150	COG0405	Gamma-glutamyltransferase
IUJ48_RS03155	COG0583	DNA-binding transcription factor activity
IUJ48_RS03160	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IUJ48_RS03165	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IUJ48_RS03170	COG3454	Phosphonate metabolism
IUJ48_RS03175	COG2188	Transcriptional regulator
IUJ48_RS03180	COG3624	Phosphonate C-P lyase system protein PhnG
IUJ48_RS03185	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IUJ48_RS03190	COG3626	phosphonate metabolism
IUJ48_RS03195	COG3627	carbon phosphorus lyase activity
IUJ48_RS03200	COG4107	phosphonate C-P lyase system protein PhnK
IUJ48_RS03205	COG4778	phosphonate C-P lyase system protein PhnL
IUJ48_RS03210	COG3454	Phosphonate metabolism
IUJ48_RS03220	COG1301	dicarboxylic acid transport
IUJ48_RS03240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IUJ48_RS03250	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IUJ48_RS03255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IUJ48_RS03260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IUJ48_RS03265	COG0009	L-threonylcarbamoyladenylate synthase
IUJ48_RS03270	COG1414	Transcriptional regulator
IUJ48_RS03275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ48_RS03290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS03295	COG0028	Belongs to the TPP enzyme family
IUJ48_RS03340	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IUJ48_RS03385	COG0028	Belongs to the TPP enzyme family
IUJ48_RS03390	COG0583	DNA-binding transcription factor activity
IUJ48_RS03395	COG4974	Belongs to the 'phage' integrase family
IUJ48_RS03400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IUJ48_RS03405	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IUJ48_RS03420	COG1686	Belongs to the peptidase S11 family
IUJ48_RS03435	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS03440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ48_RS03455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS03475	COG2070	2-Nitropropane dioxygenase
IUJ48_RS03495	COG1074	ATP-dependent DNA helicase activity
IUJ48_RS03505	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IUJ48_RS03520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS03525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_RS03535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS03550	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS03570	COG0505	Belongs to the CarA family
IUJ48_RS03575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IUJ48_RS03585	COG4221	oxidoreductase activity
IUJ48_RS03600	COG3842	ATPase activity
IUJ48_RS03620	COG2233	PERMEase
IUJ48_RS03625	COG0840	transmembrane signaling receptor activity
IUJ48_RS03630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IUJ48_RS03635	COG1534	Rna-binding protein
IUJ48_RS03640	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IUJ48_RS03645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUJ48_RS03655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ48_RS03665	COG0248	Ppx GppA phosphatase
IUJ48_RS03690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IUJ48_RS03695	COG2814	Major facilitator Superfamily
IUJ48_RS03710	COG0583	DNA-binding transcription factor activity
IUJ48_RS03715	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS03720	COG1024	Enoyl-CoA hydratase
IUJ48_RS03725	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS03725	COG1024	Enoyl-CoA hydratase
IUJ48_RS03730	COG0183	Belongs to the thiolase family
IUJ48_RS03755	COG1846	Transcriptional regulator
IUJ48_RS03765	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS03765	COG3321	synthase
IUJ48_RS03765	COG0604	alcohol dehydrogenase
IUJ48_RS03770	COG2814	Major facilitator Superfamily
IUJ48_RS03775	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ48_RS03775	COG1902	pentaerythritol trinitrate reductase activity
IUJ48_RS03785	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS03790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IUJ48_RS03795	COG1024	Enoyl-CoA hydratase
IUJ48_RS03800	COG0697	spore germination
IUJ48_RS03805	COG1024	Enoyl-CoA hydratase
IUJ48_RS03810	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS03855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IUJ48_RS03865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS03875	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS03885	COG1024	Enoyl-CoA hydratase
IUJ48_RS03890	COG1024	Enoyl-CoA hydratase
IUJ48_RS03905	COG1902	pentaerythritol trinitrate reductase activity
IUJ48_RS03915	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS03935	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS03955	COG0583	DNA-binding transcription factor activity
IUJ48_RS03970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IUJ48_RS03985	COG1024	Enoyl-CoA hydratase
IUJ48_RS03990	COG1104	cysteine desulfurase activity
IUJ48_RS03995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS04015	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS04020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ48_RS04035	COG2841	Protein conserved in bacteria
IUJ48_RS04045	COG1335	isochorismatase
IUJ48_RS04050	COG0583	DNA-binding transcription factor activity
IUJ48_RS04055	COG2207	Transcriptional regulator
IUJ48_RS04060	COG0667	Aldo Keto reductase
IUJ48_RS04075	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IUJ48_RS04090	COG0500	methyltransferase
IUJ48_RS04120	COG0517	IMP dehydrogenase activity
IUJ48_RS04135	COG3938	Belongs to the proline racemase family
IUJ48_RS04140	COG1177	transmembrane transport
IUJ48_RS04145	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_RS04150	COG3842	ATPase activity
IUJ48_RS04200	COG1511	domain protein
IUJ48_RS04200	COG3264	Mechanosensitive ion channel
IUJ48_RS04205	COG0583	DNA-binding transcription factor activity
IUJ48_RS04210	COG0427	acetyl-CoA hydrolase
IUJ48_RS04215	COG0583	DNA-binding transcription factor activity
IUJ48_RS04265	COG0583	DNA-binding transcription factor activity
IUJ48_RS04280	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS04290	COG0477	Major facilitator Superfamily
IUJ48_RS04300	COG0154	amidase activity
IUJ48_RS04320	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IUJ48_RS04335	COG0495	leucyl-tRNA aminoacylation
IUJ48_RS04340	COG2814	Major facilitator Superfamily
IUJ48_RS04345	COG1846	Transcriptional regulator
IUJ48_RS04360	COG1686	Belongs to the peptidase S11 family
IUJ48_RS04395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IUJ48_RS04400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IUJ48_RS04405	COG2814	Major facilitator Superfamily
IUJ48_RS04410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ48_RS04420	COG4176	ABC-type proline glycine betaine transport system permease component
IUJ48_RS04440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_RS04445	COG2706	6-phosphogluconolactonase activity
IUJ48_RS04450	COG4214	carbohydrate transport
IUJ48_RS04455	COG1129	ABC transporter
IUJ48_RS04460	COG4213	ABC transporter substrate-binding protein
IUJ48_RS04485	COG0583	DNA-binding transcription factor activity
IUJ48_RS04490	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS04495	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS04500	COG0183	Belongs to the thiolase family
IUJ48_RS04510	COG1802	Transcriptional regulator
IUJ48_RS04520	COG1024	Enoyl-CoA hydratase
IUJ48_RS04525	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS04535	COG0667	Aldo Keto reductase
IUJ48_RS04545	COG4120	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS04555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS04565	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IUJ48_RS04590	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IUJ48_RS04595	COG0725	ABC transporter, periplasmic molybdate-binding protein
IUJ48_RS04600	COG4149	molybdate abc transporter
IUJ48_RS04605	COG3842	ATPase activity
IUJ48_RS04630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_RS04635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_RS04645	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IUJ48_RS04650	COG0736	holo-[acyl-carrier-protein] synthase activity
IUJ48_RS04665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IUJ48_RS04675	COG0473	3-isopropylmalate dehydrogenase activity
IUJ48_RS04680	COG0583	DNA-binding transcription factor activity
IUJ48_RS04685	COG1858	cytochrome C peroxidase
IUJ48_RS04690	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IUJ48_RS04690	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IUJ48_RS04695	COG2224	Isocitrate lyase
IUJ48_RS04710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IUJ48_RS04710	COG4106	trans-aconitate 2-methyltransferase activity
IUJ48_RS04715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IUJ48_RS04715	COG4106	trans-aconitate 2-methyltransferase activity
IUJ48_RS04725	COG0156	8-amino-7-oxononanoate synthase activity
IUJ48_RS04730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ48_RS04745	COG3278	Belongs to the heme-copper respiratory oxidase family
IUJ48_RS04765	COG0348	domain, Protein
IUJ48_RS04810	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_RS04820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS04830	COG0765	amino acid transport
IUJ48_RS04835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS04895	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IUJ48_RS04900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS04905	COG0586	Pfam SNARE associated Golgi protein
IUJ48_RS04910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS04925	COG4608	Belongs to the ABC transporter superfamily
IUJ48_RS04930	COG0444	Belongs to the ABC transporter superfamily
IUJ48_RS04935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS04940	COG0601	transmembrane transport
IUJ48_RS04945	COG0583	DNA-binding transcription factor activity
IUJ48_RS04950	COG1764	response to oxidative stress
IUJ48_RS04955	COG2205	protein histidine kinase activity
IUJ48_RS04985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_RS05000	COG1802	Transcriptional regulator
IUJ48_RS05015	COG1595	DNA-templated transcription, initiation
IUJ48_RS05035	COG2084	Dehydrogenase
IUJ48_RS05045	COG1917	Cupin 2, conserved barrel domain protein
IUJ48_RS05045	COG2207	Transcriptional regulator
IUJ48_RS05055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ48_RS05065	COG0582	viral genome integration into host DNA
IUJ48_RS05110	COG3728	DNA packaging
IUJ48_RS05135	COG1280	lysine exporter protein (LysE YggA)
IUJ48_RS05140	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS05145	COG0840	transmembrane signaling receptor activity
IUJ48_RS05160	COG3387	PFAM Glycoside hydrolase 15-related
IUJ48_RS05205	COG3188	usher protein
IUJ48_RS05210	COG3121	Chaperone
IUJ48_RS05240	COG2197	response regulator
IUJ48_RS05250	COG3300	MHYT domain
IUJ48_RS05250	COG5001	Diguanylate cyclase
IUJ48_RS05265	COG3121	Chaperone
IUJ48_RS05270	COG3188	usher protein
IUJ48_RS05290	COG0642	Histidine kinase
IUJ48_RS05295	COG1475	DNA binding
IUJ48_RS05305	COG3969	phosphoadenosine phosphosulfate
IUJ48_RS05310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ48_RS05370	COG2321	neutral zinc metallopeptidase
IUJ48_RS05375	COG0009	L-threonylcarbamoyladenylate synthase
IUJ48_RS05380	COG1994	Peptidase M50
IUJ48_RS05385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_RS05390	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IUJ48_RS05400	COG2850	peptidyl-arginine hydroxylation
IUJ48_RS05405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IUJ48_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS05470	COG0583	DNA-binding transcription factor activity
IUJ48_RS05480	COG3360	Dodecin
IUJ48_RS05515	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IUJ48_RS05520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS05525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_RS05565	COG0668	transmembrane transport
IUJ48_RS05585	COG0483	inositol monophosphate 1-phosphatase activity
IUJ48_RS05590	COG4804	nuclease activity
IUJ48_RS05595	COG1477	protein flavinylation
IUJ48_RS05605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IUJ48_RS05620	COG4263	nitrous-oxide reductase activity
IUJ48_RS05635	COG1253	flavin adenine dinucleotide binding
IUJ48_RS05640	COG1968	undecaprenyl-diphosphatase activity
IUJ48_RS05645	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ48_RS05660	COG0215	cysteine-tRNA ligase activity
IUJ48_RS05670	COG0825	malonyl-CoA metabolic process
IUJ48_RS05675	COG0037	tRNA processing
IUJ48_RS05680	COG0527	aspartate kinase activity
IUJ48_RS05710	COG0348	domain, Protein
IUJ48_RS05730	COG3278	Belongs to the heme-copper respiratory oxidase family
IUJ48_RS05745	COG3258	Cytochrome c
IUJ48_RS05750	COG2863	cytochrome
IUJ48_RS05765	COG2205	protein histidine kinase activity
IUJ48_RS05765	COG0784	Response regulator, receiver
IUJ48_RS05775	COG2205	protein histidine kinase activity
IUJ48_RS05775	COG0784	Response regulator, receiver
IUJ48_RS05785	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IUJ48_RS05790	COG1051	belongs to the nudix hydrolase family
IUJ48_RS05800	COG1309	transcriptional regulator
IUJ48_RS05805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IUJ48_RS05835	COG0583	DNA-binding transcription factor activity
IUJ48_RS05855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ48_RS05865	COG1414	Transcriptional regulator
IUJ48_RS05880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IUJ48_RS05885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ48_RS05895	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IUJ48_RS05900	COG3395	kinase activity
IUJ48_RS05910	COG1132	(ABC) transporter
IUJ48_RS05920	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS05930	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS05945	COG0183	Belongs to the thiolase family
IUJ48_RS05950	COG1024	Enoyl-CoA hydratase
IUJ48_RS05950	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS05960	COG1024	Enoyl-CoA hydratase
IUJ48_RS05960	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS05970	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS05975	COG1309	transcriptional regulator
IUJ48_RS05985	COG2197	response regulator
IUJ48_RS05990	COG2197	response regulator
IUJ48_RS05995	COG0297	glycogen (starch) synthase activity
IUJ48_RS06000	COG0110	maltose O-acetyltransferase activity
IUJ48_RS06005	COG0463	Glycosyl transferase, family 2
IUJ48_RS06030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_RS06050	COG1051	belongs to the nudix hydrolase family
IUJ48_RS06060	COG1596	polysaccharide export
IUJ48_RS06065	COG3206	protein involved in exopolysaccharide biosynthesis
IUJ48_RS06065	COG0489	protein tyrosine kinase activity
IUJ48_RS06070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ48_RS06075	COG0166	Belongs to the GPI family
IUJ48_RS06080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IUJ48_RS06085	COG1045	serine acetyltransferase
IUJ48_RS06090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ48_RS06105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ48_RS06125	COG0598	Magnesium transport protein CorA
IUJ48_RS06140	COG0601	transmembrane transport
IUJ48_RS06145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS06150	COG4172	Belongs to the ABC transporter superfamily
IUJ48_RS06155	COG1846	Transcriptional regulator
IUJ48_RS06200	COG4964	Belongs to the GSP D family
IUJ48_RS06255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IUJ48_RS06270	COG3384	dioxygenase
IUJ48_RS06285	COG2814	Major facilitator Superfamily
IUJ48_RS06310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IUJ48_RS06320	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS06350	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS06355	COG3321	synthase
IUJ48_RS06355	COG0604	alcohol dehydrogenase
IUJ48_RS06370	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS06380	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS06385	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS06390	COG3246	L-lysine catabolic process to acetate
IUJ48_RS06395	COG0371	Dehydrogenase
IUJ48_RS06400	COG1802	Transcriptional regulator
IUJ48_RS06405	COG3959	Transketolase, thiamine diphosphate binding domain
IUJ48_RS06410	COG3958	Transketolase
IUJ48_RS06415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IUJ48_RS06425	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_RS06430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS06440	COG0765	amino acid transport
IUJ48_RS06450	COG2721	sulfolactate sulfo-lyase activity
IUJ48_RS06460	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS06465	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ48_RS06470	COG1414	Transcriptional regulator
IUJ48_RS06485	COG0596	Alpha beta hydrolase
IUJ48_RS06505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ48_RS06515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS06520	COG1120	ATPase activity
IUJ48_RS06535	COG4771	TonB-dependent receptor
IUJ48_RS06550	COG0477	Major facilitator Superfamily
IUJ48_RS06560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ48_RS06570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ48_RS06595	COG3852	Histidine kinase
IUJ48_RS06605	COG1546	Belongs to the CinA family
IUJ48_RS06605	COG1058	Belongs to the CinA family
IUJ48_RS06620	COG1113	amino acid transport
IUJ48_RS06630	COG1640	4-alpha-glucanotransferase
IUJ48_RS06635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IUJ48_RS06645	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IUJ48_RS06650	COG0366	Alpha amylase catalytic
IUJ48_RS06655	COG0366	Alpha amylase catalytic
IUJ48_RS06660	COG0297	glycogen (starch) synthase activity
IUJ48_RS06665	COG0392	lysyltransferase activity
IUJ48_RS06670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ48_RS06675	COG3568	Endonuclease Exonuclease Phosphatase
IUJ48_RS06680	COG0387	Pfam Sodium calcium exchanger
IUJ48_RS06710	COG0166	Belongs to the GPI family
IUJ48_RS06720	COG0668	transmembrane transport
IUJ48_RS06740	COG5265	(ABC) transporter
IUJ48_RS06750	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS06760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IUJ48_RS06770	COG2192	nodulation
IUJ48_RS06860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS06865	COG2207	Transcriptional regulator
IUJ48_RS06880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IUJ48_RS06885	COG3608	succinylglutamate desuccinylase aspartoacylase
IUJ48_RS06885	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IUJ48_RS06905	COG0505	Belongs to the CarA family
IUJ48_RS06920	COG1850	ribulose-bisphosphate carboxylase activity
IUJ48_RS06930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_RS06935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_RS06940	COG1609	Transcriptional regulator
IUJ48_RS06955	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ48_RS06960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_RS06965	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_RS06990	COG3384	dioxygenase
IUJ48_RS07045	COG0583	DNA-binding transcription factor activity
IUJ48_RS07060	COG1024	Enoyl-CoA hydratase
IUJ48_RS07105	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS07120	COG1396	sequence-specific DNA binding
IUJ48_RS07180	COG0811	peptide transport
IUJ48_RS07210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_RS07230	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
IUJ48_RS07235	COG1116	anion transmembrane transporter activity
IUJ48_RS07240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS07245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_RS07245	COG1116	anion transmembrane transporter activity
IUJ48_RS07250	COG2197	response regulator
IUJ48_RS07260	COG1131	(ABC) transporter
IUJ48_RS07265	COG0842	Transport permease protein
IUJ48_RS07280	COG0183	Belongs to the thiolase family
IUJ48_RS07305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_RS07310	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS07325	COG3321	synthase
IUJ48_RS07325	COG0604	alcohol dehydrogenase
IUJ48_RS07340	COG4638	Rieske (2fe-2S)
IUJ48_RS07370	COG1278	Cold shock
IUJ48_RS07380	COG1272	protein, Hemolysin III
IUJ48_RS07410	COG2169	Transcriptional regulator
IUJ48_RS07415	COG2814	Major facilitator Superfamily
IUJ48_RS07420	COG0583	DNA-binding transcription factor activity
IUJ48_RS07430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ48_RS07480	COG2837	iron assimilation
IUJ48_RS07520	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS07525	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IUJ48_RS07535	COG2814	Major facilitator Superfamily
IUJ48_RS07550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IUJ48_RS07555	COG2011	ABC-type metal ion transport system permease component
IUJ48_RS07590	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS07595	COG3618	amidohydrolase
IUJ48_RS07610	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
IUJ48_RS07625	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS07630	COG1473	amidohydrolase
IUJ48_RS07645	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS07650	COG2272	Belongs to the type-B carboxylesterase lipase family
IUJ48_RS07660	COG0583	DNA-binding transcription factor activity
IUJ48_RS07670	COG2951	lytic endotransglycosylase activity
IUJ48_RS07675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUJ48_RS07680	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_RS07700	COG1595	DNA-templated transcription, initiation
IUJ48_RS07715	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_RS07725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS07740	COG4172	Belongs to the ABC transporter superfamily
IUJ48_RS07750	COG1522	sequence-specific DNA binding
IUJ48_RS07810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ48_RS07820	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS07845	COG0625	glutathione transferase activity
IUJ48_RS07860	COG3530	Putative quorum-sensing-regulated virulence factor
IUJ48_RS07870	COG2814	Major facilitator Superfamily
IUJ48_RS07905	COG0443	Heat shock 70 kDa protein
IUJ48_RS07910	COG0583	DNA-binding transcription factor activity
IUJ48_RS07915	COG0494	nUDIX hydrolase
IUJ48_RS07935	COG0477	Major facilitator Superfamily
IUJ48_RS07945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ48_RS07955	COG0542	response to heat
IUJ48_RS07980	COG5441	Belongs to the UPF0261 family
IUJ48_RS07985	COG5564	TIM-barrel signal transduction protein
IUJ48_RS08000	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_RS08015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IUJ48_RS08025	COG1562	ergosterol biosynthetic process
IUJ48_RS08030	COG1562	ergosterol biosynthetic process
IUJ48_RS08035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ48_RS08040	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS08050	COG3971	2-oxopent-4-enoate hydratase activity
IUJ48_RS08065	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_RS08070	COG3384	dioxygenase
IUJ48_RS08100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ48_RS08110	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS08120	COG2186	Transcriptional regulator
IUJ48_RS08125	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IUJ48_RS08130	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS08145	COG0583	DNA-binding transcription factor activity
IUJ48_RS08150	COG0268	Binds directly to 16S ribosomal RNA
IUJ48_RS08160	COG0728	peptidoglycan biosynthetic process
IUJ48_RS08170	COG0563	adenylate kinase activity
IUJ48_RS08175	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IUJ48_RS08180	COG2835	tetraacyldisaccharide 4'-kinase activity
IUJ48_RS08190	COG1663	tetraacyldisaccharide 4'-kinase activity
IUJ48_RS08200	COG0811	peptide transport
IUJ48_RS08205	COG1570	exodeoxyribonuclease VII activity
IUJ48_RS08215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUJ48_RS08225	COG0038	chloride channel
IUJ48_RS08230	COG0183	Belongs to the thiolase family
IUJ48_RS08240	COG1278	Cold shock
IUJ48_RS08245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IUJ48_RS08250	COG2373	Large extracellular alpha-helical protein
IUJ48_RS08255	COG4953	penicillin-binding protein 1C
IUJ48_RS08265	COG2995	paraquat-inducible protein a
IUJ48_RS08270	COG3008	intermembrane lipid transfer
IUJ48_RS08280	COG0506	proline dehydrogenase activity
IUJ48_RS08280	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IUJ48_RS08280	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IUJ48_RS08310	COG2271	Major facilitator Superfamily
IUJ48_RS08330	COG0625	glutathione transferase activity
IUJ48_RS08335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_RS08345	COG1764	response to oxidative stress
IUJ48_RS08360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS08365	COG0765	amino acid transport
IUJ48_RS08370	COG0765	amino acid transport
IUJ48_RS08375	COG1126	abc transporter atp-binding protein
IUJ48_RS08380	COG1902	pentaerythritol trinitrate reductase activity
IUJ48_RS08430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IUJ48_RS08435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IUJ48_RS08440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IUJ48_RS08445	COG0196	riboflavin kinase activity
IUJ48_RS08450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IUJ48_RS08455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IUJ48_RS08455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ48_RS08470	COG0210	DNA helicase
IUJ48_RS08480	COG1858	cytochrome C peroxidase
IUJ48_RS08490	COG4771	TonB-dependent receptor
IUJ48_RS08500	COG4771	TonB-dependent receptor
IUJ48_RS08505	COG4771	TonB-dependent receptor
IUJ48_RS08520	COG0488	(ABC) transporter
IUJ48_RS08525	COG2890	protein-(glutamine-N5) methyltransferase activity
IUJ48_RS08535	COG2171	N-acyltransferase activity
IUJ48_RS08615	COG1475	DNA binding
IUJ48_RS08630	COG3546	catalase activity
IUJ48_RS08635	COG3685	Protein conserved in bacteria
IUJ48_RS08660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IUJ48_RS08760	COG0740	serine-type endopeptidase activity
IUJ48_RS08880	COG0582	viral genome integration into host DNA
IUJ48_RS08960	COG2814	Major facilitator Superfamily
IUJ48_RS08975	COG0277	FAD linked oxidase domain protein
IUJ48_RS09005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IUJ48_RS09040	COG0583	DNA-binding transcription factor activity
IUJ48_RS09050	COG0251	oxidation-reduction process
IUJ48_RS09075	COG1278	Cold shock
IUJ48_RS09085	COG1278	Cold shock
IUJ48_RS09095	COG0501	Belongs to the peptidase M48B family
IUJ48_RS09100	COG0544	peptidyl-prolyl cis-trans isomerase activity
IUJ48_RS09105	COG0740	serine-type endopeptidase activity
IUJ48_RS09110	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IUJ48_RS09115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IUJ48_RS09120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IUJ48_RS09130	COG0556	nucleotide-excision repair
IUJ48_RS09135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IUJ48_RS09145	COG1104	cysteine desulfurase activity
IUJ48_RS09150	COG0822	iron-sulfur transferase activity
IUJ48_RS09155	COG0316	Belongs to the HesB IscA family
IUJ48_RS09160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IUJ48_RS09165	COG0443	Heat shock 70 kDa protein
IUJ48_RS09170	COG0633	Ferredoxin
IUJ48_RS09175	COG2975	iron-sulfur cluster assembly
IUJ48_RS09180	COG1803	Methylglyoxal synthase
IUJ48_RS09190	COG1024	Enoyl-CoA hydratase
IUJ48_RS09220	COG1022	Amp-dependent synthetase and ligase
IUJ48_RS09225	COG0183	Belongs to the thiolase family
IUJ48_RS09230	COG1309	transcriptional regulator
IUJ48_RS09235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IUJ48_RS09240	COG3135	benzoate transporter
IUJ48_RS09255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IUJ48_RS09260	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS09270	COG2271	Major facilitator Superfamily
IUJ48_RS09290	COG1136	(ABC) transporter
IUJ48_RS09295	COG0084	hydrolase, TatD family'
IUJ48_RS09305	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS09310	COG4771	TonB-dependent receptor
IUJ48_RS09315	COG4607	ABC-type enterochelin transport system periplasmic component
IUJ48_RS09320	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS09325	COG4605	iron ion homeostasis
IUJ48_RS09330	COG4604	ABC transporter, ATP-binding protein
IUJ48_RS09345	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IUJ48_RS09370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ48_RS09375	COG4133	protoheme IX ABC transporter activity
IUJ48_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS09385	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS09390	COG0633	Ferredoxin
IUJ48_RS09420	COG1280	lysine exporter protein (LysE YggA)
IUJ48_RS09430	COG3119	arylsulfatase activity
IUJ48_RS09445	COG2304	oxidoreductase activity
IUJ48_RS09465	COG0714	Associated with various cellular activities
IUJ48_RS09470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IUJ48_RS09505	COG0459	protein refolding
IUJ48_RS09510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IUJ48_RS09520	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ48_RS09545	COG3093	addiction module antidote protein HigA
IUJ48_RS09555	COG2149	membrane
IUJ48_RS09590	COG3119	arylsulfatase activity
IUJ48_RS09600	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS09605	COG0277	FAD linked oxidase domain protein
IUJ48_RS09625	COG0159	tryptophan synthase activity
IUJ48_RS09635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ48_RS09640	COG0477	Major facilitator Superfamily
IUJ48_RS09645	COG0583	DNA-binding transcription factor activity
IUJ48_RS09655	COG0583	DNA-binding transcription factor activity
IUJ48_RS09665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ48_RS09680	COG0613	PHP domain protein
IUJ48_RS09690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_RS09695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_RS09695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_RS09705	COG0047	phosphoribosylformylglycinamidine synthase activity
IUJ48_RS09705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IUJ48_RS09710	COG4774	siderophore transport
IUJ48_RS09715	COG3712	iron ion homeostasis
IUJ48_RS09720	COG1595	DNA-templated transcription, initiation
IUJ48_RS09745	COG0642	Histidine kinase
IUJ48_RS09760	COG0583	DNA-binding transcription factor activity
IUJ48_RS09770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IUJ48_RS09780	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS09790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_RS09795	COG0583	DNA-binding transcription factor activity
IUJ48_RS09800	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS09825	COG3292	Two component regulator propeller
IUJ48_RS09825	COG2205	protein histidine kinase activity
IUJ48_RS09825	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS09830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS09830	COG0784	Response regulator, receiver
IUJ48_RS09830	COG2205	protein histidine kinase activity
IUJ48_RS09830	COG2198	Histidine kinase
IUJ48_RS09835	COG0583	DNA-binding transcription factor activity
IUJ48_RS09870	COG1953	Uracil, thiamine, allantoin
IUJ48_RS09920	COG0583	DNA-binding transcription factor activity
IUJ48_RS09935	COG4774	siderophore transport
IUJ48_RS09940	COG4774	siderophore transport
IUJ48_RS09945	COG5001	Diguanylate cyclase
IUJ48_RS10000	COG0583	DNA-binding transcription factor activity
IUJ48_RS10025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ48_RS10075	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS10080	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IUJ48_RS10085	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS10090	COG0583	DNA-binding transcription factor activity
IUJ48_RS10105	COG0747	negative chemotaxis
IUJ48_RS10110	COG4608	Belongs to the ABC transporter superfamily
IUJ48_RS10120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS10125	COG0601	transmembrane transport
IUJ48_RS10130	COG2072	flavoprotein involved in K transport
IUJ48_RS10190	COG0419	ATPase involved in DNA repair
IUJ48_RS10500	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS10505	COG0583	DNA-binding transcription factor activity
IUJ48_RS10535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ48_RS10545	COG0583	DNA-binding transcription factor activity
IUJ48_RS10575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ48_RS10575	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_RS10600	COG4691	Plasmid stability protein
IUJ48_RS10630	COG0798	PFAM Bile acid sodium symporter
IUJ48_RS10675	COG0582	viral genome integration into host DNA
IUJ48_RS10750	COG3077	Addiction module antitoxin, RelB DinJ family
IUJ48_RS10760	COG1475	DNA binding
IUJ48_RS10770	COG5489	Protein of unknown function (DUF736)
IUJ48_RS10800	COG1192	Involved in chromosome partitioning
IUJ48_RS10825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ48_RS10835	COG2814	Major facilitator Superfamily
IUJ48_RS10860	COG0640	Transcriptional regulator
IUJ48_RS10865	COG1230	cation diffusion facilitator family transporter
IUJ48_RS10870	COG1937	Protein conserved in bacteria
IUJ48_RS10875	COG2814	Major facilitator Superfamily
IUJ48_RS10880	COG0640	Transcriptional regulator
IUJ48_RS10890	COG0789	Transcriptional regulator
IUJ48_RS10895	COG0633	Ferredoxin
IUJ48_RS10930	COG3621	Patatin-like phospholipase
IUJ48_RS10950	COG3328	transposase activity
IUJ48_RS10965	COG4264	IucA IucC family
IUJ48_RS11000	COG0431	NADPH-dependent FMN reductase
IUJ48_RS11005	COG0583	DNA-binding transcription factor activity
IUJ48_RS11010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IUJ48_RS11020	COG0640	Transcriptional regulator
IUJ48_RS11025	COG0640	Transcriptional regulator
IUJ48_RS11055	COG2207	Transcriptional regulator
IUJ48_RS11060	COG4221	oxidoreductase activity
IUJ48_RS11070	COG2267	carboxylic ester hydrolase activity
IUJ48_RS11075	COG2207	Transcriptional regulator
IUJ48_RS11095	COG2205	protein histidine kinase activity
IUJ48_RS11110	COG0583	DNA-binding transcription factor activity
IUJ48_RS11125	COG0165	Argininosuccinate lyase
IUJ48_RS11145	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IUJ48_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS11210	COG0456	acetyltransferase
IUJ48_RS11240	COG0583	DNA-binding transcription factor activity
IUJ48_RS11255	COG0154	amidase activity
IUJ48_RS11260	COG0840	transmembrane signaling receptor activity
IUJ48_RS11285	COG2201	protein-glutamate methylesterase activity
IUJ48_RS11290	COG2203	Gaf domain
IUJ48_RS11290	COG4251	negative regulation of phosphorylation
IUJ48_RS11290	COG5001	Diguanylate cyclase
IUJ48_RS11290	COG3706	GGDEF domain
IUJ48_RS11295	COG4149	molybdate abc transporter
IUJ48_RS11300	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ48_RS11305	COG3842	ATPase activity
IUJ48_RS11310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS11315	COG1522	sequence-specific DNA binding
IUJ48_RS11325	COG2010	Cytochrome c
IUJ48_RS11325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IUJ48_RS11330	COG1335	isochorismatase
IUJ48_RS11335	COG2309	aminopeptidase activity
IUJ48_RS11340	COG0596	Alpha beta hydrolase
IUJ48_RS11350	COG2080	2 iron, 2 sulfur cluster binding
IUJ48_RS11355	COG2010	Cytochrome c
IUJ48_RS11355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IUJ48_RS11360	COG0477	Major facilitator Superfamily
IUJ48_RS11365	COG1846	Transcriptional regulator
IUJ48_RS11375	COG0583	DNA-binding transcription factor activity
IUJ48_RS11390	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IUJ48_RS11400	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS11405	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS11410	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS11415	COG0183	Belongs to the thiolase family
IUJ48_RS11420	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS11420	COG1024	Enoyl-CoA hydratase
IUJ48_RS11425	COG0583	DNA-binding transcription factor activity
IUJ48_RS11450	COG0148	phosphopyruvate hydratase activity
IUJ48_RS11460	COG2733	membrane
IUJ48_RS11465	COG2032	superoxide dismutase activity
IUJ48_RS11470	COG0625	glutathione transferase activity
IUJ48_RS11650	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
IUJ48_RS11660	COG1360	Flagellar Motor Protein
IUJ48_RS11715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS11735	COG3541	Predicted nucleotidyltransferase
IUJ48_RS11740	COG1846	Transcriptional regulator
IUJ48_RS11770	COG0583	DNA-binding transcription factor activity
IUJ48_RS11780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ48_RS11790	COG0697	spore germination
IUJ48_RS11800	COG4941	Belongs to the sigma-70 factor family
IUJ48_RS11810	COG3795	YCII-related domain
IUJ48_RS11815	COG3795	YCII-related domain
IUJ48_RS11830	COG2885	chlorophyll binding
IUJ48_RS11830	COG3047	cAMP biosynthetic process
IUJ48_RS11850	COG2207	Transcriptional regulator
IUJ48_RS11860	COG1683	Conserved Protein
IUJ48_RS11880	COG1309	transcriptional regulator
IUJ48_RS11885	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS11895	COG0667	Aldo Keto reductase
IUJ48_RS11900	COG0477	Major facilitator Superfamily
IUJ48_RS11910	COG1414	Transcriptional regulator
IUJ48_RS11920	COG2345	Transcriptional regulator
IUJ48_RS11925	COG4774	siderophore transport
IUJ48_RS11945	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IUJ48_RS12025	COG0840	transmembrane signaling receptor activity
IUJ48_RS12050	COG3038	cytochrome b561
IUJ48_RS12090	COG0583	DNA-binding transcription factor activity
IUJ48_RS12095	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS12105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IUJ48_RS12115	COG0667	Aldo Keto reductase
IUJ48_RS12135	COG0587	DNA-directed DNA polymerase activity
IUJ48_RS12155	COG0833	amino acid
IUJ48_RS12160	COG0400	carboxylic ester hydrolase activity
IUJ48_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS12180	COG0028	Belongs to the TPP enzyme family
IUJ48_RS12195	COG1566	PFAM secretion protein HlyD family protein
IUJ48_RS12205	COG1289	transmembrane transporter activity
IUJ48_RS12215	COG0720	synthase
IUJ48_RS12220	COG0602	queuosine metabolic process
IUJ48_RS12225	COG0513	Belongs to the DEAD box helicase family
IUJ48_RS12230	COG1414	Transcriptional regulator
IUJ48_RS12245	COG0747	negative chemotaxis
IUJ48_RS12250	COG0601	transmembrane transport
IUJ48_RS12255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS12260	COG4172	Belongs to the ABC transporter superfamily
IUJ48_RS12265	COG1228	amidohydrolase
IUJ48_RS12270	COG0523	cobalamin synthesis protein
IUJ48_RS12280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS12285	COG0235	Class ii aldolase
IUJ48_RS12300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS12305	COG1595	DNA-templated transcription, initiation
IUJ48_RS12310	COG3712	iron ion homeostasis
IUJ48_RS12325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS12330	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IUJ48_RS12335	COG4521	taurine ABC transporter
IUJ48_RS12340	COG0583	DNA-binding transcription factor activity
IUJ48_RS12365	COG1966	Carbon starvation protein
IUJ48_RS12370	COG2879	small protein
IUJ48_RS12375	COG0697	spore germination
IUJ48_RS12380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS12410	COG0783	Belongs to the Dps family
IUJ48_RS12425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ48_RS12430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ48_RS12440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IUJ48_RS12445	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IUJ48_RS12450	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS12455	COG5002	protein histidine kinase activity
IUJ48_RS12460	COG0574	Belongs to the PEP-utilizing enzyme family
IUJ48_RS12460	COG3848	Pyruvate phosphate dikinase
IUJ48_RS12470	COG2070	2-Nitropropane dioxygenase
IUJ48_RS12490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS12520	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS12530	COG0583	DNA-binding transcription factor activity
IUJ48_RS12575	COG2223	nitrite transmembrane transporter activity
IUJ48_RS12580	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IUJ48_RS12585	COG1140	nitrate reductase beta subunit
IUJ48_RS12590	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IUJ48_RS12595	COG2181	nitrate reductase activity
IUJ48_RS12600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_RS12605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IUJ48_RS12610	COG0288	reversible hydration of carbon dioxide
IUJ48_RS12615	COG1763	Mo-molybdopterin cofactor biosynthetic process
IUJ48_RS12620	COG3850	Histidine kinase
IUJ48_RS12625	COG2197	response regulator
IUJ48_RS12630	COG0826	peptidase U32
IUJ48_RS12635	COG0826	peptidase U32
IUJ48_RS12640	COG3154	lipid carrier protein
IUJ48_RS12645	COG4597	amino acid ABC transporter
IUJ48_RS12650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS12685	COG1116	anion transmembrane transporter activity
IUJ48_RS12685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_RS12690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_RS12695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS12720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ48_RS12735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_RS12740	COG1802	Transcriptional regulator
IUJ48_RS12750	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_RS12790	COG0251	oxidation-reduction process
IUJ48_RS12815	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IUJ48_RS12840	COG0436	Aminotransferase
IUJ48_RS12845	COG0765	amino acid transport
IUJ48_RS12855	COG1126	abc transporter atp-binding protein
IUJ48_RS12875	COG0583	DNA-binding transcription factor activity
IUJ48_RS12905	COG4566	intracellular signal transduction
IUJ48_RS12910	COG4191	Histidine kinase
IUJ48_RS12920	COG1846	Transcriptional regulator
IUJ48_RS12930	COG0583	DNA-binding transcription factor activity
IUJ48_RS12935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IUJ48_RS12960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ48_RS12970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_RS12975	COG2070	2-Nitropropane dioxygenase
IUJ48_RS12980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS12985	COG0765	amino acid transport
IUJ48_RS12990	COG1126	abc transporter atp-binding protein
IUJ48_RS12995	COG1120	ATPase activity
IUJ48_RS13000	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS13005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS13050	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IUJ48_RS13060	COG0390	transport system, permease component
IUJ48_RS13065	COG0586	Pfam SNARE associated Golgi protein
IUJ48_RS13080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ48_RS13085	COG3842	ATPase activity
IUJ48_RS13090	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IUJ48_RS13095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS13105	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS13125	COG2721	sulfolactate sulfo-lyase activity
IUJ48_RS13130	COG3386	PFAM SMP-30 Gluconolaconase
IUJ48_RS13135	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS13155	COG1276	copper resistance
IUJ48_RS13165	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_RS13165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ48_RS13170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_RS13180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS13185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS13190	COG2358	TRAP transporter, solute receptor (TAXI family
IUJ48_RS13200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ48_RS13205	COG1335	isochorismatase
IUJ48_RS13210	COG0583	DNA-binding transcription factor activity
IUJ48_RS13220	COG0747	negative chemotaxis
IUJ48_RS13225	COG0601	transmembrane transport
IUJ48_RS13235	COG0444	Belongs to the ABC transporter superfamily
IUJ48_RS13255	COG0583	DNA-binding transcription factor activity
IUJ48_RS13260	COG0626	cystathionine gamma-synthase activity
IUJ48_RS13265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS13270	COG4597	amino acid ABC transporter
IUJ48_RS13275	COG0765	amino acid transport
IUJ48_RS13280	COG1126	abc transporter atp-binding protein
IUJ48_RS13300	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IUJ48_RS13310	COG0640	Transcriptional regulator
IUJ48_RS13320	COG0798	PFAM Bile acid sodium symporter
IUJ48_RS13330	COG0431	NADPH-dependent FMN reductase
IUJ48_RS13345	COG0625	glutathione transferase activity
IUJ48_RS13360	COG0579	oxidoreductase
IUJ48_RS13370	COG0477	Major facilitator Superfamily
IUJ48_RS13385	COG0625	glutathione transferase activity
IUJ48_RS13415	COG3971	2-oxopent-4-enoate hydratase activity
IUJ48_RS13425	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ48_RS13440	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IUJ48_RS13455	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ48_RS13475	COG0251	oxidation-reduction process
IUJ48_RS13485	COG0747	negative chemotaxis
IUJ48_RS13490	COG0601	transmembrane transport
IUJ48_RS13500	COG0444	Belongs to the ABC transporter superfamily
IUJ48_RS13505	COG4608	Belongs to the ABC transporter superfamily
IUJ48_RS13510	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_RS13520	COG0531	amino acid
IUJ48_RS13535	COG1619	proteins homologs of microcin C7 resistance protein MccF
IUJ48_RS13545	COG0628	permease
IUJ48_RS13565	COG0793	Belongs to the peptidase S41A family
IUJ48_RS13590	COG4521	taurine ABC transporter
IUJ48_RS13595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS13600	COG1116	anion transmembrane transporter activity
IUJ48_RS13630	COG3706	GGDEF domain
IUJ48_RS13640	COG0789	Transcriptional regulator
IUJ48_RS13825	COG2205	protein histidine kinase activity
IUJ48_RS13835	COG1253	flavin adenine dinucleotide binding
IUJ48_RS13870	COG4774	siderophore transport
IUJ48_RS13885	COG5001	Diguanylate cyclase
IUJ48_RS13885	COG3300	MHYT domain
IUJ48_RS13890	COG1289	transmembrane transporter activity
IUJ48_RS13900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ48_RS13920	COG0693	protein deglycase activity
IUJ48_RS13940	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS13975	COG2204	response regulator
IUJ48_RS13980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IUJ48_RS14005	COG2814	Major facilitator Superfamily
IUJ48_RS14020	COG3300	MHYT domain
IUJ48_RS14020	COG5001	Diguanylate cyclase
IUJ48_RS14025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ48_RS14030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS14055	COG0488	(ABC) transporter
IUJ48_RS14060	COG0688	phosphatidylethanolamine metabolic process
IUJ48_RS14070	COG1408	metallophosphoesterase
IUJ48_RS14080	COG2814	Major facilitator Superfamily
IUJ48_RS14090	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_RS14100	COG0010	Belongs to the arginase family
IUJ48_RS14120	COG2363	Small membrane protein
IUJ48_RS14125	COG0697	spore germination
IUJ48_RS14135	COG2133	pyrroloquinoline quinone binding
IUJ48_RS14140	COG0625	glutathione transferase activity
IUJ48_RS14145	COG0583	DNA-binding transcription factor activity
IUJ48_RS14155	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_RS14160	COG1794	racemase activity, acting on amino acids and derivatives
IUJ48_RS14185	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS14200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IUJ48_RS14210	COG1653	transport
IUJ48_RS14215	COG1175	transmembrane transport
IUJ48_RS14220	COG0395	ABC-type sugar transport system, permease component
IUJ48_RS14225	COG3842	ATPase activity
IUJ48_RS14240	COG2205	protein histidine kinase activity
IUJ48_RS14245	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS14260	COG3866	Pectate lyase
IUJ48_RS14265	COG4783	chaperone-mediated protein folding
IUJ48_RS14265	COG1560	Kdo2-lipid A biosynthetic process
IUJ48_RS14290	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS14295	COG0457	Tetratricopeptide repeat
IUJ48_RS14305	COG0783	Belongs to the Dps family
IUJ48_RS14315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IUJ48_RS14325	COG0583	DNA-binding transcription factor activity
IUJ48_RS14340	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS14350	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ48_RS14355	COG4149	molybdate abc transporter
IUJ48_RS14360	COG3842	ATPase activity
IUJ48_RS14365	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS14370	COG1690	Belongs to the RtcB family
IUJ48_RS14375	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IUJ48_RS14380	COG1741	Belongs to the pirin family
IUJ48_RS14385	COG1741	Belongs to the pirin family
IUJ48_RS14390	COG0583	DNA-binding transcription factor activity
IUJ48_RS14395	COG2204	response regulator
IUJ48_RS14405	COG0174	glutamine synthetase
IUJ48_RS14410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUJ48_RS14415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IUJ48_RS14430	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS14440	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IUJ48_RS14445	COG1561	YicC-like family, N-terminal region
IUJ48_RS14450	COG0833	amino acid
IUJ48_RS14455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IUJ48_RS14470	COG0791	NLP P60 protein
IUJ48_RS14475	COG3210	domain, Protein
IUJ48_RS14480	COG2831	hemolysin activation secretion protein
IUJ48_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS14495	COG2863	cytochrome
IUJ48_RS14500	COG3258	Cytochrome c
IUJ48_RS14505	COG0194	GDP metabolic process
IUJ48_RS14510	COG1758	RNA polymerase activity
IUJ48_RS14515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ48_RS14525	COG1335	isochorismatase
IUJ48_RS14530	COG1126	abc transporter atp-binding protein
IUJ48_RS14535	COG0765	amino acid transport
IUJ48_RS14540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS14575	COG2816	NAD+ diphosphatase activity
IUJ48_RS14595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS14625	COG4336	lyase activity
IUJ48_RS14630	COG0583	DNA-binding transcription factor activity
IUJ48_RS14645	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_RS14660	COG0583	DNA-binding transcription factor activity
IUJ48_RS14675	COG0560	Phosphoserine phosphatase
IUJ48_RS14680	COG0583	DNA-binding transcription factor activity
IUJ48_RS14685	COG3842	ATPase activity
IUJ48_RS14690	COG1178	ABC-type Fe3 transport system permease component
IUJ48_RS14700	COG4181	ATPase activity
IUJ48_RS14710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_RS14720	COG0584	glycerophosphoryl diester phosphodiesterase
IUJ48_RS14725	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IUJ48_RS14735	COG0678	peroxiredoxin activity
IUJ48_RS14735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ48_RS14750	COG0789	Transcriptional regulator
IUJ48_RS14755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IUJ48_RS14760	COG2814	Major facilitator Superfamily
IUJ48_RS14765	COG0583	DNA-binding transcription factor activity
IUJ48_RS14790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUJ48_RS14800	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IUJ48_RS14805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IUJ48_RS14810	COG2252	PERMEase
IUJ48_RS14820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_RS14825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_RS14860	COG0488	(ABC) transporter
IUJ48_RS14865	COG1619	proteins homologs of microcin C7 resistance protein MccF
IUJ48_RS14885	COG1320	monovalent cation:proton antiporter activity
IUJ48_RS14890	COG2212	antiporter activity
IUJ48_RS14895	COG1863	multisubunit Na H antiporter MnhE subunit
IUJ48_RS14900	COG0651	ATP synthesis coupled electron transport
IUJ48_RS14905	COG1006	Multisubunit Na H antiporter MnhC subunit
IUJ48_RS14910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IUJ48_RS14910	COG2111	Na H antiporter
IUJ48_RS14940	COG0420	3'-5' exonuclease activity
IUJ48_RS14945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS14980	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS14985	COG1959	2 iron, 2 sulfur cluster binding
IUJ48_RS14990	COG3634	alkyl hydroperoxide reductase activity
IUJ48_RS15010	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS15015	COG0346	lactoylglutathione lyase activity
IUJ48_RS15060	COG0395	ABC-type sugar transport system, permease component
IUJ48_RS15070	COG3842	ATPase activity
IUJ48_RS15075	COG3842	ATPase activity
IUJ48_RS15100	COG2130	NADP-dependent
IUJ48_RS15115	COG1131	(ABC) transporter
IUJ48_RS15120	COG0842	Transport permease protein
IUJ48_RS15135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IUJ48_RS15165	COG1902	pentaerythritol trinitrate reductase activity
IUJ48_RS15200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS15215	COG0840	transmembrane signaling receptor activity
IUJ48_RS15225	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IUJ48_RS15245	COG2814	Major facilitator Superfamily
IUJ48_RS15250	COG0386	Belongs to the glutathione peroxidase family
IUJ48_RS15255	COG1522	sequence-specific DNA binding
IUJ48_RS15265	COG0625	glutathione transferase activity
IUJ48_RS15280	COG0095	Lipoate-protein ligase
IUJ48_RS15290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IUJ48_RS15300	COG0010	Belongs to the arginase family
IUJ48_RS15305	COG1126	abc transporter atp-binding protein
IUJ48_RS15310	COG0765	amino acid transport
IUJ48_RS15315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS15330	COG0084	hydrolase, TatD family'
IUJ48_RS15335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IUJ48_RS15340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IUJ48_RS15345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IUJ48_RS15370	COG1024	Enoyl-CoA hydratase
IUJ48_RS15370	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS15380	COG2914	Belongs to the UPF0125 (RnfH) family
IUJ48_RS15385	COG2867	negative regulation of translational initiation
IUJ48_RS15390	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IUJ48_RS15410	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_RS15410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ48_RS15415	COG2169	Transcriptional regulator
IUJ48_RS15415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ48_RS15435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ48_RS15440	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IUJ48_RS15455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUJ48_RS15460	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ48_RS15465	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IUJ48_RS15470	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ48_RS15475	COG0750	zinc metalloprotease
IUJ48_RS15480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IUJ48_RS15490	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IUJ48_RS15495	COG0233	cytoplasmic translational termination
IUJ48_RS15500	COG0528	UMP kinase activity
IUJ48_RS15505	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IUJ48_RS15510	COG0052	Belongs to the universal ribosomal protein uS2 family
IUJ48_RS15515	COG0024	Methionine aminopeptidase
IUJ48_RS15520	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IUJ48_RS15530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IUJ48_RS15535	COG1451	nucleotide metabolic process
IUJ48_RS15555	COG0285	dihydrofolate synthase activity
IUJ48_RS15565	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS15570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS15580	COG1414	Transcriptional regulator
IUJ48_RS15585	COG1334	flagellar protein FlaG
IUJ48_RS15590	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IUJ48_RS15610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IUJ48_RS15620	COG1677	Flagellar hook-basal body complex protein FliE
IUJ48_RS15625	COG1766	The M ring may be actively involved in energy transduction
IUJ48_RS15630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IUJ48_RS15655	COG1580	Controls the rotational direction of flagella during chemotaxis
IUJ48_RS15665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IUJ48_RS15690	COG0840	transmembrane signaling receptor activity
IUJ48_RS15695	COG0840	transmembrane signaling receptor activity
IUJ48_RS15705	COG0840	transmembrane signaling receptor activity
IUJ48_RS15710	COG0840	transmembrane signaling receptor activity
IUJ48_RS15745	COG4787	bacterial-type flagellum-dependent cell motility
IUJ48_RS15760	COG1558	bacterial-type flagellum-dependent cell motility
IUJ48_RS15765	COG1815	bacterial-type flagellum-dependent cell motility
IUJ48_RS15775	COG2747	anti-sigma28 factor FlgM
IUJ48_RS15800	COG0840	transmembrane signaling receptor activity
IUJ48_RS15805	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IUJ48_RS15810	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS15815	COG2201	protein-glutamate methylesterase activity
IUJ48_RS15820	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IUJ48_RS15825	COG0840	transmembrane signaling receptor activity
IUJ48_RS15830	COG0835	chemotaxis
IUJ48_RS15840	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS15845	COG1360	Flagellar Motor Protein
IUJ48_RS15865	COG1191	sigma factor activity
IUJ48_RS15870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ48_RS15870	COG4797	methyltransferase
IUJ48_RS15890	COG0583	DNA-binding transcription factor activity
IUJ48_RS15915	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ48_RS15920	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IUJ48_RS15930	COG4566	intracellular signal transduction
IUJ48_RS15935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IUJ48_RS15940	COG0339	signal peptide processing
IUJ48_RS15950	COG1999	signal sequence binding
IUJ48_RS15975	COG0583	DNA-binding transcription factor activity
IUJ48_RS15980	COG1187	pseudouridine synthase activity
IUJ48_RS15985	COG3161	chorismate lyase activity
IUJ48_RS15990	COG0477	Major facilitator Superfamily
IUJ48_RS16005	COG4681	YaeQ
IUJ48_RS16010	COG4172	Belongs to the ABC transporter superfamily
IUJ48_RS16015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS16020	COG0601	transmembrane transport
IUJ48_RS16025	COG0747	negative chemotaxis
IUJ48_RS16035	COG0583	DNA-binding transcription factor activity
IUJ48_RS16065	COG2165	general secretion pathway protein
IUJ48_RS16140	COG0668	transmembrane transport
IUJ48_RS16145	COG0165	Argininosuccinate lyase
IUJ48_RS16165	COG0022	dehydrogenase e1 component
IUJ48_RS16175	COG4774	siderophore transport
IUJ48_RS16200	COG0789	Transcriptional regulator
IUJ48_RS16210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ48_RS16220	COG2271	Major facilitator Superfamily
IUJ48_RS16230	COG0307	riboflavin synthase, alpha
IUJ48_RS16235	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_RS16245	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS16265	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IUJ48_RS16300	COG0154	amidase activity
IUJ48_RS16305	COG2814	Major facilitator Superfamily
IUJ48_RS16315	COG2226	methyltransferase
IUJ48_RS16340	COG0583	DNA-binding transcription factor activity
IUJ48_RS16350	COG0583	DNA-binding transcription factor activity
IUJ48_RS16360	COG0583	DNA-binding transcription factor activity
IUJ48_RS16365	COG1132	(ABC) transporter
IUJ48_RS16395	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS16400	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS16415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_RS16425	COG5265	(ABC) transporter
IUJ48_RS16430	COG1280	lysine exporter protein (LysE YggA)
IUJ48_RS16470	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS16475	COG2188	Transcriptional regulator
IUJ48_RS16490	COG0477	Major facilitator Superfamily
IUJ48_RS16495	COG0235	Class ii aldolase
IUJ48_RS16535	COG2610	gluconate transmembrane transporter activity
IUJ48_RS16540	COG0583	DNA-binding transcription factor activity
IUJ48_RS16545	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS16550	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IUJ48_RS16590	COG1024	Enoyl-CoA hydratase
IUJ48_RS16595	COG5001	Diguanylate cyclase
IUJ48_RS16600	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS16605	COG0129	dihydroxy-acid dehydratase activity
IUJ48_RS16615	COG0583	DNA-binding transcription factor activity
IUJ48_RS16620	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS16625	COG3246	L-lysine catabolic process to acetate
IUJ48_RS16645	COG3043	anaerobic respiration
IUJ48_RS16650	COG3005	denitrification pathway
IUJ48_RS16655	COG4133	protoheme IX ABC transporter activity
IUJ48_RS16675	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IUJ48_RS16685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_RS16695	COG4235	cytochrome complex assembly
IUJ48_RS16715	COG3381	protein complex oligomerization
IUJ48_RS16740	COG4133	protoheme IX ABC transporter activity
IUJ48_RS16760	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IUJ48_RS16770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_RS16775	COG3088	subunit of a heme lyase
IUJ48_RS16795	COG5001	Diguanylate cyclase
IUJ48_RS16795	COG1716	ATPase activity
IUJ48_RS16810	COG2205	protein histidine kinase activity
IUJ48_RS16810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS16815	COG0784	Response regulator, receiver
IUJ48_RS16815	COG2205	protein histidine kinase activity
IUJ48_RS16815	COG2198	Histidine kinase
IUJ48_RS16815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS16825	COG3121	Chaperone
IUJ48_RS16855	COG1595	DNA-templated transcription, initiation
IUJ48_RS16860	COG3712	iron ion homeostasis
IUJ48_RS16880	COG1304	FMN binding
IUJ48_RS16890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ48_RS16895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_RS16900	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS16905	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS16920	COG2207	Transcriptional regulator
IUJ48_RS16955	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS16965	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IUJ48_RS16970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ48_RS16980	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS16985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IUJ48_RS16990	COG0534	Mate efflux family protein
IUJ48_RS17005	COG0697	spore germination
IUJ48_RS17010	COG0697	spore germination
IUJ48_RS17025	COG1280	lysine exporter protein (LysE YggA)
IUJ48_RS17040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IUJ48_RS17045	COG3245	cytochrome
IUJ48_RS17055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ48_RS17085	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS17090	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS17105	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IUJ48_RS17110	COG2814	Major facilitator Superfamily
IUJ48_RS17125	COG0625	glutathione transferase activity
IUJ48_RS17135	COG0583	DNA-binding transcription factor activity
IUJ48_RS17155	COG0506	proline dehydrogenase activity
IUJ48_RS17160	COG0697	spore germination
IUJ48_RS17165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS17195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ48_RS17200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ48_RS17210	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUJ48_RS17250	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS17255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUJ48_RS17260	COG1610	YqeY-like protein
IUJ48_RS17290	COG0457	Tetratricopeptide repeat
IUJ48_RS17295	COG1649	PFAM Uncharacterised BCR, COG1649
IUJ48_RS17295	COG0726	polysaccharide deacetylase
IUJ48_RS17300	COG1215	transferase activity, transferring glycosyl groups
IUJ48_RS17310	COG2223	nitrite transmembrane transporter activity
IUJ48_RS17315	COG1917	Cupin 2, conserved barrel domain protein
IUJ48_RS17315	COG4977	sequence-specific DNA binding
IUJ48_RS17325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IUJ48_RS17340	COG0656	L-ascorbic acid biosynthetic process
IUJ48_RS17345	COG5265	(ABC) transporter
IUJ48_RS17375	COG1116	anion transmembrane transporter activity
IUJ48_RS17400	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS17405	COG0583	DNA-binding transcription factor activity
IUJ48_RS17435	COG1522	sequence-specific DNA binding
IUJ48_RS17470	COG0456	acetyltransferase
IUJ48_RS17475	COG0384	phenazine biosynthesis protein PhzF
IUJ48_RS17500	COG2814	Major facilitator Superfamily
IUJ48_RS17530	COG0072	phenylalanine-tRNA ligase activity
IUJ48_RS17530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ48_RS17535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IUJ48_RS17540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IUJ48_RS17545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IUJ48_RS17555	COG2960	long-chain fatty acid transporting porin activity
IUJ48_RS17565	COG0347	Belongs to the P(II) protein family
IUJ48_RS17570	COG0004	ammonium transporteR
IUJ48_RS17575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IUJ48_RS17580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ48_RS17595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IUJ48_RS17600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IUJ48_RS17610	COG2197	response regulator
IUJ48_RS17615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUJ48_RS17645	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_RS17655	COG0601	transmembrane transport
IUJ48_RS17660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS17665	COG4172	Belongs to the ABC transporter superfamily
IUJ48_RS17685	COG1609	Transcriptional regulator
IUJ48_RS17690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_RS17695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_RS17700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_RS17705	COG0129	dihydroxy-acid dehydratase activity
IUJ48_RS17740	COG0596	Alpha beta hydrolase
IUJ48_RS17760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ48_RS17765	COG0101	tRNA pseudouridine synthase activity
IUJ48_RS17775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IUJ48_RS17795	COG1538	Outer membrane efflux protein
IUJ48_RS17810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_RS17840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IUJ48_RS17865	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IUJ48_RS17875	COG1295	ribonuclease BN
IUJ48_RS17885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IUJ48_RS17915	COG4964	Belongs to the GSP D family
IUJ48_RS17945	COG2755	lipolytic protein G-D-S-L family
IUJ48_RS17945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IUJ48_RS17955	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS17975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IUJ48_RS17980	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IUJ48_RS17985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IUJ48_RS17990	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IUJ48_RS17995	COG0330	HflC and HflK could
IUJ48_RS18000	COG0330	HflC and HflK could
IUJ48_RS18005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IUJ48_RS18010	COG1923	regulation of RNA biosynthetic process
IUJ48_RS18015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ48_RS18020	COG1160	GTP binding
IUJ48_RS18025	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ48_RS18030	COG2976	Protein conserved in bacteria
IUJ48_RS18055	COG0105	UTP biosynthetic process
IUJ48_RS18060	COG0525	valine-tRNA ligase activity
IUJ48_RS18065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS18070	COG1126	abc transporter atp-binding protein
IUJ48_RS18075	COG0765	amino acid transport
IUJ48_RS18080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS18085	COG1396	sequence-specific DNA binding
IUJ48_RS18090	COG0336	Belongs to the RNA methyltransferase TrmD family
IUJ48_RS18100	COG0228	four-way junction DNA binding
IUJ48_RS18110	COG0425	Belongs to the sulfur carrier protein TusA family
IUJ48_RS18115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IUJ48_RS18130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS18145	COG2076	Multidrug Resistance protein
IUJ48_RS18150	COG0633	Ferredoxin
IUJ48_RS18150	COG3217	Mosc domain protein beta barrel domain protein
IUJ48_RS18155	COG5285	phytanoyl-CoA dioxygenase
IUJ48_RS18160	COG0662	Cupin 2, conserved barrel domain protein
IUJ48_RS18185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ48_RS18190	COG2311	Membrane
IUJ48_RS18195	COG1309	transcriptional regulator
IUJ48_RS18220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IUJ48_RS18230	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IUJ48_RS18235	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IUJ48_RS18255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUJ48_RS18265	COG3391	amine dehydrogenase activity
IUJ48_RS18295	COG1846	Transcriptional regulator
IUJ48_RS18305	COG1566	PFAM secretion protein HlyD family protein
IUJ48_RS18310	COG2814	Major facilitator Superfamily
IUJ48_RS18320	COG0473	3-isopropylmalate dehydrogenase activity
IUJ48_RS18325	COG0433	COG0433 Predicted ATPase
IUJ48_RS18330	COG0217	transcriptional regulatory protein
IUJ48_RS18335	COG0151	Belongs to the GarS family
IUJ48_RS18345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IUJ48_RS18350	COG0799	negative regulation of ribosome biogenesis
IUJ48_RS18355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IUJ48_RS18365	COG1301	dicarboxylic acid transport
IUJ48_RS18370	COG4191	Histidine kinase
IUJ48_RS18375	COG2204	response regulator
IUJ48_RS18405	COG1530	ribonuclease E activity
IUJ48_RS18415	COG3706	GGDEF domain
IUJ48_RS18415	COG4251	negative regulation of phosphorylation
IUJ48_RS18415	COG5001	Diguanylate cyclase
IUJ48_RS18415	COG2203	Gaf domain
IUJ48_RS18425	COG0475	glutathione-regulated potassium exporter activity
IUJ48_RS18425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ48_RS18430	COG1132	(ABC) transporter
IUJ48_RS18455	COG0726	polysaccharide deacetylase
IUJ48_RS18470	COG0726	polysaccharide deacetylase
IUJ48_RS18475	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS18490	COG1116	anion transmembrane transporter activity
IUJ48_RS18495	COG0395	ABC-type sugar transport system, permease component
IUJ48_RS18500	COG1643	Atp-dependent helicase
IUJ48_RS18505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IUJ48_RS18505	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IUJ48_RS18510	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IUJ48_RS18520	COG0704	Plays a role in the regulation of phosphate uptake
IUJ48_RS18530	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS18540	COG1322	Protein conserved in bacteria
IUJ48_RS18560	COG1177	transmembrane transport
IUJ48_RS18565	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_RS18570	COG3842	ATPase activity
IUJ48_RS18580	COG3642	lipopolysaccharide core region biosynthetic process
IUJ48_RS18590	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IUJ48_RS18595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_RS18605	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_RS18605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_RS18615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IUJ48_RS18620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IUJ48_RS18625	COG0596	Alpha beta hydrolase
IUJ48_RS18625	COG2945	thiolester hydrolase activity
IUJ48_RS18645	COG3618	amidohydrolase
IUJ48_RS18650	COG0583	DNA-binding transcription factor activity
IUJ48_RS18655	COG0137	argininosuccinate synthase activity
IUJ48_RS18660	COG3158	transport of potassium into the cell
IUJ48_RS18665	COG0642	Histidine kinase
IUJ48_RS18695	COG0776	regulation of translation
IUJ48_RS18700	COG3128	pkhd-type hydroxylase
IUJ48_RS18710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ48_RS18715	COG0557	exoribonuclease II activity
IUJ48_RS18745	COG0679	Auxin Efflux Carrier
IUJ48_RS18750	COG2391	methyltransferase activity
IUJ48_RS18755	COG0069	glutamate synthase activity
IUJ48_RS18760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ48_RS18770	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IUJ48_RS18805	COG0697	spore germination
IUJ48_RS18920	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IUJ48_RS18930	COG0628	permease
IUJ48_RS18960	COG3909	cytochrome
IUJ48_RS18970	COG0625	glutathione transferase activity
IUJ48_RS18975	COG0730	response to heat
IUJ48_RS18980	COG0482	sulfurtransferase activity
IUJ48_RS18985	COG0583	DNA-binding transcription factor activity
IUJ48_RS19015	COG0247	lactate metabolic process
IUJ48_RS19020	COG0277	FAD linked oxidase domain protein
IUJ48_RS19025	COG0277	FAD linked oxidase domain protein
IUJ48_RS19030	COG0277	FAD linked oxidase domain protein
IUJ48_RS19035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ48_RS19040	COG0312	modulator of DNA gyrase
IUJ48_RS19055	COG0308	aminopeptidase N
IUJ48_RS19060	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IUJ48_RS19080	COG0436	Aminotransferase
IUJ48_RS19090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUJ48_RS19095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IUJ48_RS19115	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS19155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IUJ48_RS19175	COG0181	hydroxymethylbilane synthase activity
IUJ48_RS19180	COG0861	Integral membrane protein TerC family
IUJ48_RS19185	COG0861	Integral membrane protein TerC family
IUJ48_RS19190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IUJ48_RS19195	COG0045	succinate-CoA ligase (ADP-forming) activity
IUJ48_RS19220	COG2137	regulation of response to DNA damage stimulus
IUJ48_RS19225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IUJ48_RS19260	COG0540	Belongs to the ATCase OTCase family
IUJ48_RS19310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS19345	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IUJ48_RS19355	COG0305	Participates in initiation and elongation during chromosome replication
IUJ48_RS19365	COG0359	binds to the 23S rRNA
IUJ48_RS19370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IUJ48_RS19375	COG2965	DNA replication, synthesis of RNA primer
IUJ48_RS19380	COG0360	Binds together with S18 to 16S ribosomal RNA
IUJ48_RS19385	COG3739	integral membrane protein
IUJ48_RS19390	COG1469	GTP cyclohydrolase I activity
IUJ48_RS19400	COG0142	geranyltranstransferase activity
IUJ48_RS19405	COG1722	exodeoxyribonuclease VII activity
IUJ48_RS19415	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS19435	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ48_RS19440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ48_RS19450	COG3842	ATPase activity
IUJ48_RS19455	COG0583	DNA-binding transcription factor activity
IUJ48_RS19475	COG0501	Belongs to the peptidase M48B family
IUJ48_RS19480	COG1760	l-serine dehydratase
IUJ48_RS19490	COG0412	Dienelactone hydrolase
IUJ48_RS19505	COG1611	Belongs to the LOG family
IUJ48_RS19510	COG1473	amidohydrolase
IUJ48_RS19515	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS19535	COG1217	gtp-binding protein TYPA
IUJ48_RS19540	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IUJ48_RS19545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IUJ48_RS19550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IUJ48_RS19555	COG0195	Participates in both transcription termination and antitermination
IUJ48_RS19555	COG2251	uridine kinase activity
IUJ48_RS19560	COG0779	Required for maturation of 30S ribosomal subunits
IUJ48_RS19565	COG1187	pseudouridine synthase activity
IUJ48_RS19570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IUJ48_RS19585	COG0583	DNA-binding transcription factor activity
IUJ48_RS19590	COG0523	cobalamin synthesis protein
IUJ48_RS19595	COG0523	cobalamin synthesis protein
IUJ48_RS19615	COG0642	Histidine kinase
IUJ48_RS19620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_RS19625	COG0625	glutathione transferase activity
IUJ48_RS19630	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IUJ48_RS19640	COG2003	Belongs to the UPF0758 family
IUJ48_RS19645	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IUJ48_RS19650	COG3483	tryptophan 2,3-dioxygenase activity
IUJ48_RS19665	COG0534	Mate efflux family protein
IUJ48_RS19675	COG2050	protein possibly involved in aromatic compounds catabolism
IUJ48_RS19680	COG1024	Enoyl-CoA hydratase
IUJ48_RS19685	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_RS19690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ48_RS19695	COG2151	metal-sulfur cluster biosynthetic enzyme
IUJ48_RS19700	COG3396	Phenylacetate-CoA oxygenase
IUJ48_RS19705	COG3460	Phenylacetate-CoA oxygenase
IUJ48_RS19710	COG3396	Phenylacetate-CoA oxygenase
IUJ48_RS19715	COG3327	negative regulation of DNA-templated transcription, initiation
IUJ48_RS19720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IUJ48_RS19725	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IUJ48_RS19730	COG0501	Belongs to the peptidase M48B family
IUJ48_RS19735	COG1162	GTPase activity
IUJ48_RS19740	COG0494	nUDIX hydrolase
IUJ48_RS19745	COG0335	large ribosomal subunit rRNA binding
IUJ48_RS19775	COG0175	sulfate reduction
IUJ48_RS19785	COG4208	sulfate ABC transporter
IUJ48_RS19790	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IUJ48_RS19800	COG0450	alkyl hydroperoxide reductase
IUJ48_RS19805	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS19810	COG2985	domain, Protein
IUJ48_RS19835	COG0123	including yeast histone deacetylase and acetoin utilization protein
IUJ48_RS19840	COG2951	lytic endotransglycosylase activity
IUJ48_RS19870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_RS19875	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IUJ48_RS19880	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IUJ48_RS19900	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IUJ48_RS19905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IUJ48_RS19915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ48_RS19925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IUJ48_RS19940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IUJ48_RS19965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IUJ48_RS19975	COG1215	transferase activity, transferring glycosyl groups
IUJ48_RS19995	COG1696	Membrane protein involved in D-alanine export
IUJ48_RS20005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ48_RS20015	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS20030	COG2951	lytic endotransglycosylase activity
IUJ48_RS20035	COG2258	MOSC domain
IUJ48_RS20040	COG2833	Protein of unknown function (DUF455)
IUJ48_RS20055	COG1132	(ABC) transporter
IUJ48_RS20060	COG0189	ligase activity
IUJ48_RS20060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IUJ48_RS20065	COG0189	ligase activity
IUJ48_RS20065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IUJ48_RS20070	COG3237	CsbD-like
IUJ48_RS20080	COG2823	Periplasmic or secreted lipoprotein
IUJ48_RS20100	COG3210	domain, Protein
IUJ48_RS20105	COG2831	hemolysin activation secretion protein
IUJ48_RS20130	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
IUJ48_RS20135	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS20140	COG3243	poly(R)-hydroxyalkanoic acid synthase
IUJ48_RS20145	COG1496	oxidoreductase activity
IUJ48_RS20150	COG0564	pseudouridine synthase activity
IUJ48_RS20160	COG1199	ATP-dependent helicase activity
IUJ48_RS20165	COG2183	response to ionizing radiation
IUJ48_RS20200	COG4774	siderophore transport
IUJ48_RS20205	COG3712	iron ion homeostasis
IUJ48_RS20210	COG1595	DNA-templated transcription, initiation
IUJ48_RS20215	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IUJ48_RS20220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ48_RS20225	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ48_RS20230	COG0567	Dehydrogenase, E1 component
IUJ48_RS20235	COG1522	sequence-specific DNA binding
IUJ48_RS20240	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IUJ48_RS20255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ48_RS20260	COG1297	OPT oligopeptide transporter protein
IUJ48_RS20270	COG0280	phosphate acetyltransferase
IUJ48_RS20270	COG0281	malic enzyme
IUJ48_RS20285	COG0372	Belongs to the citrate synthase family
IUJ48_RS20290	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IUJ48_RS20295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IUJ48_RS20300	COG1053	succinate dehydrogenase
IUJ48_RS20305	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IUJ48_RS20310	COG2009	succinate dehydrogenase
IUJ48_RS20315	COG2188	Transcriptional regulator
IUJ48_RS20320	COG0039	L-malate dehydrogenase activity
IUJ48_RS20340	COG1981	membrane
IUJ48_RS20375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ48_RS20385	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IUJ48_RS20400	COG0148	phosphopyruvate hydratase activity
IUJ48_RS20410	COG0504	CTP synthase activity
IUJ48_RS20445	COG0747	negative chemotaxis
IUJ48_RS20450	COG4172	Belongs to the ABC transporter superfamily
IUJ48_RS20455	COG1446	asparaginase
IUJ48_RS20465	COG2153	protein acetylation
IUJ48_RS20490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_RS20510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ48_RS20515	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IUJ48_RS20520	COG0697	spore germination
IUJ48_RS20525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ48_RS20535	COG3193	protein, possibly involved in utilization of glycolate and propanediol
IUJ48_RS20545	COG0791	NLP P60 protein
IUJ48_RS20555	COG0583	DNA-binding transcription factor activity
IUJ48_RS20580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUJ48_RS20630	COG1381	Involved in DNA repair and RecF pathway recombination
IUJ48_RS20635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IUJ48_RS20640	COG0571	ribonuclease III activity
IUJ48_RS20645	COG0681	Belongs to the peptidase S26 family
IUJ48_RS20650	COG0481	GTPase activity
IUJ48_RS20655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_RS20680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUJ48_RS20685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ48_RS20695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IUJ48_RS20700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ48_RS20710	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IUJ48_RS20720	COG0424	maF-like protein
IUJ48_RS20735	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
IUJ48_RS20740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IUJ48_RS20745	COG0546	phosphoglycolate phosphatase activity
IUJ48_RS20750	COG0564	pseudouridine synthase activity
IUJ48_RS20755	COG1530	ribonuclease E activity
IUJ48_RS20760	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IUJ48_RS20765	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IUJ48_RS20770	COG0159	tryptophan synthase activity
IUJ48_RS20780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ48_RS20790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ48_RS20795	COG3228	Belongs to the MtfA family
IUJ48_RS20805	COG0251	oxidation-reduction process
IUJ48_RS20810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IUJ48_RS20815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IUJ48_RS20830	COG2878	Part of a membrane complex involved in electron transport
IUJ48_RS20835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IUJ48_RS20870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IUJ48_RS20905	COG1268	BioY protein
IUJ48_RS20910	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IUJ48_RS20915	COG1122	ATPase activity
IUJ48_RS20920	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ48_RS20925	COG2917	probably involved in intracellular septation
IUJ48_RS20935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_RS20940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IUJ48_RS20950	COG1196	nuclear chromosome segregation
IUJ48_RS20955	COG0477	Major facilitator Superfamily
IUJ48_RS20960	COG1573	uracil-dna glycosylase
IUJ48_RS20965	COG1214	PFAM Peptidase M22, glycoprotease
IUJ48_RS20980	COG0450	alkyl hydroperoxide reductase
IUJ48_RS20985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ48_RS20995	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IUJ48_RS21000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IUJ48_RS21005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IUJ48_RS21010	COG0560	Phosphoserine phosphatase
IUJ48_RS21015	COG4774	siderophore transport
IUJ48_RS21020	COG4774	siderophore transport
IUJ48_RS21030	COG1007	ATP synthesis coupled electron transport
IUJ48_RS21045	COG0713	ATP synthesis coupled electron transport
IUJ48_RS21055	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ48_RS21060	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IUJ48_RS21065	COG1034	ATP synthesis coupled electron transport
IUJ48_RS21075	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IUJ48_RS21080	COG0649	NAD binding
IUJ48_RS21085	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ48_RS21090	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ48_RS21095	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ48_RS21100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS21125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ48_RS21145	COG0583	DNA-binding transcription factor activity
IUJ48_RS21150	COG1309	transcriptional regulator
IUJ48_RS21160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_RS21180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_RS21185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_RS21190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ48_RS21200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_RS21205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_RS21225	COG0747	negative chemotaxis
IUJ48_RS21235	COG4172	Belongs to the ABC transporter superfamily
IUJ48_RS21255	COG1522	sequence-specific DNA binding
IUJ48_RS21260	COG4772	TonB-dependent receptor
IUJ48_RS21265	COG2354	Protein conserved in bacteria
IUJ48_RS21270	COG3813	Protein conserved in bacteria
IUJ48_RS21275	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
IUJ48_RS21280	COG3604	Transcriptional regulator
IUJ48_RS21295	COG0784	Response regulator, receiver
IUJ48_RS21295	COG4191	Histidine kinase
IUJ48_RS21300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IUJ48_RS21320	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS21325	COG2851	Citrate transporter
IUJ48_RS21335	COG0642	Histidine kinase
IUJ48_RS21355	COG3712	iron ion homeostasis
IUJ48_RS21360	COG1595	DNA-templated transcription, initiation
IUJ48_RS21375	COG1116	anion transmembrane transporter activity
IUJ48_RS21410	COG1910	domain protein
IUJ48_RS21430	COG0840	transmembrane signaling receptor activity
IUJ48_RS21455	COG2885	chlorophyll binding
IUJ48_RS21455	COG3047	cAMP biosynthetic process
IUJ48_RS21470	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IUJ48_RS21475	COG0149	triose-phosphate isomerase activity
IUJ48_RS21500	COG2207	Transcriptional regulator
IUJ48_RS21520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ48_RS21530	COG1185	polyribonucleotide nucleotidyltransferase activity
IUJ48_RS21535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IUJ48_RS21545	COG1183	phosphatidylcholine synthase activity
IUJ48_RS21550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IUJ48_RS21555	COG0440	acetolactate synthase activity
IUJ48_RS21560	COG0028	Belongs to the TPP enzyme family
IUJ48_RS21565	COG1289	transmembrane transporter activity
IUJ48_RS21570	COG3022	response to hydroperoxide
IUJ48_RS21575	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS21595	COG1132	(ABC) transporter
IUJ48_RS21595	COG2375	cellular response to nickel ion
IUJ48_RS21600	COG1132	(ABC) transporter
IUJ48_RS21605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS21610	COG4605	iron ion homeostasis
IUJ48_RS21615	COG4604	ABC transporter, ATP-binding protein
IUJ48_RS21620	COG4607	ABC-type enterochelin transport system periplasmic component
IUJ48_RS21625	COG4774	siderophore transport
IUJ48_RS21635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_RS21675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IUJ48_RS21680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IUJ48_RS21685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ48_RS21700	COG0601	transmembrane transport
IUJ48_RS21720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IUJ48_RS21720	COG0517	IMP dehydrogenase activity
IUJ48_RS21725	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_RS21730	COG0251	oxidation-reduction process
IUJ48_RS21735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IUJ48_RS21740	COG1674	ftsk spoiiie
IUJ48_RS21745	COG0492	ferredoxin-NADP+ reductase activity
IUJ48_RS21750	COG1193	negative regulation of DNA recombination
IUJ48_RS21760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ48_RS21775	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IUJ48_RS21780	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IUJ48_RS21785	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IUJ48_RS21790	COG2205	protein histidine kinase activity
IUJ48_RS21795	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS21810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_RS21815	COG0840	transmembrane signaling receptor activity
IUJ48_RS21850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUJ48_RS21875	COG0612	Peptidase, M16
IUJ48_RS21885	COG0484	heat shock protein binding
IUJ48_RS21890	COG0443	Heat shock 70 kDa protein
IUJ48_RS21900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IUJ48_RS21910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IUJ48_RS21915	COG1420	regulation of RNA biosynthetic process
IUJ48_RS21925	COG0497	DNA recombination
IUJ48_RS21930	COG0735	belongs to the Fur family
IUJ48_RS21935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ48_RS21960	COG0582	viral genome integration into host DNA
IUJ48_RS21965	COG0583	DNA-binding transcription factor activity
IUJ48_RS21975	COG1021	2,3-dihydroxybenzoate-AMP ligase
IUJ48_RS21995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ48_RS21995	COG2226	methyltransferase
IUJ48_RS21995	COG3433	isochorismatase activity
IUJ48_RS22035	COG4106	trans-aconitate 2-methyltransferase activity
IUJ48_RS22045	COG2814	Major facilitator Superfamily
IUJ48_RS22050	COG1132	(ABC) transporter
IUJ48_RS22050	COG2375	cellular response to nickel ion
IUJ48_RS22065	COG4771	TonB-dependent receptor
IUJ48_RS22095	COG0640	Transcriptional regulator
IUJ48_RS22100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ48_RS22160	COG4774	siderophore transport
IUJ48_RS22165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUJ48_RS22170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ48_RS22185	COG0019	diaminopimelate decarboxylase activity
IUJ48_RS22195	COG1131	(ABC) transporter
IUJ48_RS22220	COG4771	TonB-dependent receptor
IUJ48_RS22235	COG2807	transmembrane transport
IUJ48_RS22255	COG0024	Methionine aminopeptidase
IUJ48_RS22270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ48_RS22385	COG3311	Transcriptional regulator
IUJ48_RS22390	COG1569	PIN domain
IUJ48_RS22395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUJ48_RS22490	COG3344	reverse transcriptase
IUJ48_RS22515	COG3344	reverse transcriptase
IUJ48_RS22585	COG0789	Transcriptional regulator
IUJ48_RS22625	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IUJ48_RS22635	COG0789	Transcriptional regulator
IUJ48_RS22655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IUJ48_RS22660	COG0629	single-stranded DNA binding
IUJ48_RS22750	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IUJ48_RS22755	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IUJ48_RS22760	COG0167	dihydroorotate dehydrogenase activity
IUJ48_RS22775	COG1414	Transcriptional regulator
IUJ48_RS22780	COG1546	Belongs to the CinA family
IUJ48_RS22780	COG1058	Belongs to the CinA family
IUJ48_RS22795	COG0513	Belongs to the DEAD box helicase family
IUJ48_RS22805	COG4771	TonB-dependent receptor
IUJ48_RS22810	COG2814	Major facilitator Superfamily
IUJ48_RS22850	COG4783	chaperone-mediated protein folding
IUJ48_RS22865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS22870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IUJ48_RS22885	COG0006	proline dipeptidase activity
IUJ48_RS22895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_RS22920	COG0632	four-way junction helicase activity
IUJ48_RS22925	COG1090	epimerase
IUJ48_RS22935	COG2255	four-way junction helicase activity
IUJ48_RS22940	COG4191	Histidine kinase
IUJ48_RS22955	COG0514	ATP-dependent DNA helicase (RecQ)
IUJ48_RS22960	COG1294	oxidase, subunit
IUJ48_RS22970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ48_RS22975	COG0850	regulation of cytokinetic process
IUJ48_RS22980	COG2894	cell division
IUJ48_RS22985	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IUJ48_RS23010	COG0488	(ABC) transporter
IUJ48_RS23015	COG2746	aminoglycoside 3-N-acetyltransferase activity
IUJ48_RS23035	COG4608	Belongs to the ABC transporter superfamily
IUJ48_RS23040	COG0444	Belongs to the ABC transporter superfamily
IUJ48_RS23045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS23050	COG0601	transmembrane transport
IUJ48_RS23055	COG0747	negative chemotaxis
IUJ48_RS23080	COG4638	Rieske (2fe-2S)
IUJ48_RS23085	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IUJ48_RS23105	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IUJ48_RS23110	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS23135	COG0463	Glycosyl transferase, family 2
IUJ48_RS23135	COG1216	Glycosyl transferase, family 2
IUJ48_RS23150	COG0800	Aldolase
IUJ48_RS23160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IUJ48_RS23200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IUJ48_RS23205	COG1566	PFAM secretion protein HlyD family protein
IUJ48_RS23215	COG0577	efflux transmembrane transporter activity
IUJ48_RS23215	COG1136	(ABC) transporter
IUJ48_RS23265	COG0583	DNA-binding transcription factor activity
IUJ48_RS23270	COG1538	Outer membrane efflux protein
IUJ48_RS23275	COG0577	efflux transmembrane transporter activity
IUJ48_RS23275	COG1136	(ABC) transporter
IUJ48_RS23280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_RS23295	COG0259	pyridoxamine-phosphate oxidase activity
IUJ48_RS23305	COG0579	oxidoreductase
IUJ48_RS23315	COG0583	DNA-binding transcription factor activity
IUJ48_RS23325	COG2175	clavaminate synthase activity
IUJ48_RS23335	COG1304	FMN binding
IUJ48_RS23345	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ48_RS23350	COG0583	DNA-binding transcription factor activity
IUJ48_RS23355	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS23365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS23370	COG0531	amino acid
IUJ48_RS23385	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS23395	COG0114	fumarate hydratase activity
IUJ48_RS23400	COG0802	atpase or kinase
IUJ48_RS23405	COG0860	N-Acetylmuramoyl-L-alanine amidase
IUJ48_RS23415	COG0586	Pfam SNARE associated Golgi protein
IUJ48_RS23420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IUJ48_RS23425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IUJ48_RS23435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IUJ48_RS23450	COG0617	tRNA 3'-terminal CCA addition
IUJ48_RS23460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ48_RS23465	COG2301	Belongs to the HpcH HpaI aldolase family
IUJ48_RS23475	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IUJ48_RS23485	COG1024	Enoyl-CoA hydratase
IUJ48_RS23495	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS23505	COG0183	Belongs to the thiolase family
IUJ48_RS23510	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS23520	COG2070	2-Nitropropane dioxygenase
IUJ48_RS23535	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS23540	COG2030	dehydratase
IUJ48_RS23545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_RS23565	COG1024	Enoyl-CoA hydratase
IUJ48_RS23570	COG0752	glycyl-tRNA synthetase alpha subunit
IUJ48_RS23575	COG0751	glycine-tRNA ligase activity
IUJ48_RS23580	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IUJ48_RS23585	COG0204	Acyl-transferase
IUJ48_RS23605	COG0242	peptide deformylase activity
IUJ48_RS23610	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS23615	COG0700	Nucleoside recognition
IUJ48_RS23620	COG0469	pyruvate kinase activity
IUJ48_RS23625	COG1929	Belongs to the glycerate kinase type-1 family
IUJ48_RS23630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IUJ48_RS23635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_RS23645	COG3178	'Phosphotransferase
IUJ48_RS23660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_RS23675	COG2154	pterin-4-alpha-carbinolamine dehydratase
IUJ48_RS23710	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS23725	COG2982	Protein involved in outer membrane biogenesis
IUJ48_RS23730	COG1368	sulfuric ester hydrolase activity
IUJ48_RS23735	COG2818	Glycosylase
IUJ48_RS23760	COG0735	belongs to the Fur family
IUJ48_RS23770	COG0583	DNA-binding transcription factor activity
IUJ48_RS23775	COG0840	transmembrane signaling receptor activity
IUJ48_RS23795	COG3712	iron ion homeostasis
IUJ48_RS23800	COG1595	DNA-templated transcription, initiation
IUJ48_RS23815	COG2011	ABC-type metal ion transport system permease component
IUJ48_RS23820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IUJ48_RS23825	COG1501	Belongs to the glycosyl hydrolase 31 family
IUJ48_RS23830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS23830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IUJ48_RS23835	COG0483	inositol monophosphate 1-phosphatase activity
IUJ48_RS23840	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS23845	COG1473	amidohydrolase
IUJ48_RS23850	COG0583	DNA-binding transcription factor activity
IUJ48_RS23855	COG2855	membrane
IUJ48_RS23865	COG2239	Acts as a magnesium transporter
IUJ48_RS23880	COG1522	sequence-specific DNA binding
IUJ48_RS23885	COG0300	oxidoreductase activity
IUJ48_RS23895	COG0028	Belongs to the TPP enzyme family
IUJ48_RS23925	COG0739	heme binding
IUJ48_RS23935	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IUJ48_RS23940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IUJ48_RS23950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IUJ48_RS23955	COG1181	Belongs to the D-alanine--D-alanine ligase family
IUJ48_RS23960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUJ48_RS23965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IUJ48_RS23975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IUJ48_RS23980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IUJ48_RS23985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IUJ48_RS23995	COG3116	cell division
IUJ48_RS24000	COG0275	rRNA processing
IUJ48_RS24005	COG2001	Belongs to the MraZ family
IUJ48_RS24015	COG0488	(ABC) transporter
IUJ48_RS24020	COG0418	dihydroorotase activity
IUJ48_RS24025	COG1473	amidohydrolase
IUJ48_RS24035	COG0583	DNA-binding transcription factor activity
IUJ48_RS24075	COG1522	sequence-specific DNA binding
IUJ48_RS24085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ48_RS24090	COG4654	Cytochrome c, class I
IUJ48_RS24095	COG0129	dihydroxy-acid dehydratase activity
IUJ48_RS24135	COG0405	Gamma-glutamyltransferase
IUJ48_RS24140	COG2084	Dehydrogenase
IUJ48_RS24155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_RS24185	COG0442	prolyl-tRNA aminoacylation
IUJ48_RS24190	COG0824	Thioesterase
IUJ48_RS24195	COG0811	peptide transport
IUJ48_RS24200	COG0848	biopolymer transport protein
IUJ48_RS24210	COG0823	Involved in the tonB-independent uptake of proteins
IUJ48_RS24225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS24230	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IUJ48_RS24245	COG1522	sequence-specific DNA binding
IUJ48_RS24255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IUJ48_RS24270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS24275	COG0697	spore germination
IUJ48_RS24285	COG1346	cytolysis
IUJ48_RS24295	COG0583	DNA-binding transcription factor activity
IUJ48_RS24305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_RS24325	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS24345	COG0583	DNA-binding transcription factor activity
IUJ48_RS24360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IUJ48_RS24365	COG0463	Glycosyl transferase, family 2
IUJ48_RS24375	COG0786	glutamate:sodium symporter activity
IUJ48_RS24390	COG1671	Belongs to the UPF0178 family
IUJ48_RS24405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUJ48_RS24410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_RS24420	COG0328	RNA-DNA hybrid ribonuclease activity
IUJ48_RS24425	COG2226	methyltransferase
IUJ48_RS24430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ48_RS24435	COG0741	lytic transglycosylase activity
IUJ48_RS24435	COG1388	LysM domain
IUJ48_RS24475	COG1366	Belongs to the anti-sigma-factor antagonist family
IUJ48_RS24480	COG2172	sigma factor antagonist activity
IUJ48_RS24485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ48_RS24495	COG2208	phosphoserine phosphatase activity
IUJ48_RS24495	COG2770	Histidine kinase
IUJ48_RS24515	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS24525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ48_RS24535	COG1942	4-Oxalocrotonate Tautomerase
IUJ48_RS24540	COG0583	DNA-binding transcription factor activity
IUJ48_RS24550	COG2719	SpoVR family
IUJ48_RS24555	COG2718	Belongs to the UPF0229 family
IUJ48_RS24560	COG2766	serine protein kinase
IUJ48_RS24575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ48_RS24575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ48_RS24590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IUJ48_RS24595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IUJ48_RS24610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IUJ48_RS24625	COG0316	Belongs to the HesB IscA family
IUJ48_RS24635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IUJ48_RS24640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IUJ48_RS24645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IUJ48_RS24660	COG4177	L-phenylalanine transmembrane transporter activity
IUJ48_RS24675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ48_RS24680	COG0312	modulator of DNA gyrase
IUJ48_RS24685	COG3028	Belongs to the UPF0307 family
IUJ48_RS24700	COG1116	anion transmembrane transporter activity
IUJ48_RS24705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS24710	COG1335	isochorismatase
IUJ48_RS24715	COG0045	succinate-CoA ligase (ADP-forming) activity
IUJ48_RS24715	COG1042	CoA-binding domain protein
IUJ48_RS24715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ48_RS24720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ48_RS24735	COG0583	DNA-binding transcription factor activity
IUJ48_RS24745	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS24750	COG1522	sequence-specific DNA binding
IUJ48_RS24785	COG1696	Membrane protein involved in D-alanine export
IUJ48_RS24810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IUJ48_RS24810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IUJ48_RS24820	COG2264	protein methyltransferase activity
IUJ48_RS24825	COG0439	Biotin carboxylase
IUJ48_RS24830	COG0511	ligase activity, forming carbon-carbon bonds
IUJ48_RS24835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IUJ48_RS24840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_RS24845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUJ48_RS24850	COG3150	esterase
IUJ48_RS24855	COG0557	exoribonuclease II activity
IUJ48_RS24875	COG1175	transmembrane transport
IUJ48_RS24880	COG3842	ATPase activity
IUJ48_RS24890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IUJ48_RS24895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUJ48_RS24905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IUJ48_RS24910	COG1126	abc transporter atp-binding protein
IUJ48_RS24915	COG0765	amino acid transport
IUJ48_RS24925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS24930	COG0436	Aminotransferase
IUJ48_RS24935	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ48_RS24960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IUJ48_RS24965	COG1678	Uncharacterized ACR, COG1678
IUJ48_RS24980	COG0352	thiamine-phosphate diphosphorylase activity
IUJ48_RS24985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IUJ48_RS24990	COG0741	lytic transglycosylase activity
IUJ48_RS25000	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS25005	COG1335	isochorismatase
IUJ48_RS25010	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IUJ48_RS25015	COG4638	Rieske (2fe-2S)
IUJ48_RS25055	COG1024	Enoyl-CoA hydratase
IUJ48_RS25060	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS25095	COG0410	ABC transporter
IUJ48_RS25130	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IUJ48_RS25150	COG3842	ATPase activity
IUJ48_RS25155	COG1175	transmembrane transport
IUJ48_RS25160	COG3833	ABC-type maltose transport systems, permease component
IUJ48_RS25175	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_RS25180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_RS25210	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IUJ48_RS25215	COG0237	dephospho-CoA kinase activity
IUJ48_RS25235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IUJ48_RS25240	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IUJ48_RS25250	COG0477	Major facilitator Superfamily
IUJ48_RS25285	COG1605	Chorismate mutase
IUJ48_RS25285	COG0077	Prephenate dehydratase
IUJ48_RS25295	COG2081	HI0933 family
IUJ48_RS25300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_RS25315	COG4177	L-phenylalanine transmembrane transporter activity
IUJ48_RS25320	COG1129	ABC transporter
IUJ48_RS25345	COG1126	abc transporter atp-binding protein
IUJ48_RS25350	COG0765	amino acid transport
IUJ48_RS25355	COG4597	amino acid ABC transporter
IUJ48_RS25360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS25365	COG2884	Cell division ATP-binding protein ftsE
IUJ48_RS25370	COG2177	Part of the ABC transporter FtsEX involved in
IUJ48_RS25395	COG1194	a g-specific adenine glycosylase
IUJ48_RS25410	COG0246	Mannitol dehydrogenase
IUJ48_RS25415	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_RS25420	COG1126	abc transporter atp-binding protein
IUJ48_RS25425	COG0765	amino acid transport
IUJ48_RS25435	COG1063	alcohol dehydrogenase
IUJ48_RS25450	COG2186	Transcriptional regulator
IUJ48_RS25460	COG4771	TonB-dependent receptor
IUJ48_RS25465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IUJ48_RS25470	COG2022	thiamine diphosphate biosynthetic process
IUJ48_RS25475	COG0351	phosphomethylpyrimidine kinase
IUJ48_RS25480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUJ48_RS25490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IUJ48_RS25500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IUJ48_RS25515	COG2226	methyltransferase
IUJ48_RS25520	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS25545	COG2132	Multicopper oxidase
IUJ48_RS25560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_RS25570	COG0583	DNA-binding transcription factor activity
IUJ48_RS25580	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IUJ48_RS25585	COG1984	allophanate hydrolase subunit 2
IUJ48_RS25595	COG1802	Transcriptional regulator
IUJ48_RS25600	COG2860	membrane
IUJ48_RS25610	COG2223	nitrite transmembrane transporter activity
IUJ48_RS25615	COG2813	Specifically methylates the guanine in position
IUJ48_RS25615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ48_RS25620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ48_RS25625	COG2188	Transcriptional regulator
IUJ48_RS25630	COG2721	sulfolactate sulfo-lyase activity
IUJ48_RS25635	COG2721	sulfolactate sulfo-lyase activity
IUJ48_RS25645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_RS25650	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IUJ48_RS25680	COG2918	glutathione biosynthetic process
IUJ48_RS25690	COG2988	succinylglutamate desuccinylase activity
IUJ48_RS25700	COG0583	DNA-binding transcription factor activity
IUJ48_RS25710	COG1802	Transcriptional regulator
IUJ48_RS25725	COG1129	ABC transporter
IUJ48_RS25745	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ48_RS25760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS25765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ48_RS25770	COG1595	DNA-templated transcription, initiation
IUJ48_RS25780	COG0583	DNA-binding transcription factor activity
IUJ48_RS25785	COG1764	response to oxidative stress
IUJ48_RS25800	COG2814	Major facilitator Superfamily
IUJ48_RS25815	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS25830	COG1309	transcriptional regulator
IUJ48_RS25840	COG1024	Enoyl-CoA hydratase
IUJ48_RS25845	COG1024	Enoyl-CoA hydratase
IUJ48_RS25850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IUJ48_RS25860	COG0747	negative chemotaxis
IUJ48_RS25865	COG0583	DNA-binding transcription factor activity
IUJ48_RS25875	COG2988	succinylglutamate desuccinylase activity
IUJ48_RS25880	COG0747	negative chemotaxis
IUJ48_RS25885	COG0601	transmembrane transport
IUJ48_RS25895	COG0444	Belongs to the ABC transporter superfamily
IUJ48_RS25900	COG4608	Belongs to the ABC transporter superfamily
IUJ48_RS25910	COG2195	Cleaves the N-terminal amino acid of tripeptides
IUJ48_RS25920	COG2171	N-acyltransferase activity
IUJ48_RS25930	COG4221	oxidoreductase activity
IUJ48_RS25935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IUJ48_RS25950	COG0210	DNA helicase
IUJ48_RS25955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IUJ48_RS25960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IUJ48_RS25970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IUJ48_RS25980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IUJ48_RS25985	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IUJ48_RS25990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IUJ48_RS26005	COG0356	it plays a direct role in the translocation of protons across the membrane
IUJ48_RS26020	COG1024	Enoyl-CoA hydratase
IUJ48_RS26025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_RS26035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ48_RS26050	COG0583	DNA-binding transcription factor activity
IUJ48_RS26055	COG3473	Maleate cis-trans isomerase
IUJ48_RS26080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ48_RS26095	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS26100	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS26130	COG0037	tRNA processing
IUJ48_RS26140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ48_RS26145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_RS26155	COG2967	ApaG domain
IUJ48_RS26160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IUJ48_RS26165	COG0546	phosphoglycolate phosphatase activity
IUJ48_RS26175	COG0512	Glutamine amidotransferase of anthranilate synthase
IUJ48_RS26180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IUJ48_RS26185	COG0134	indole-3-glycerol-phosphate synthase activity
IUJ48_RS26190	COG3284	Transcriptional regulator
IUJ48_RS26195	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_RS26230	COG0709	Synthesizes selenophosphate from selenide and ATP
IUJ48_RS26235	COG1305	Transglutaminase-like
IUJ48_RS26240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_RS26245	COG1216	Glycosyl transferase, family 2
IUJ48_RS26255	COG3276	selenocysteine insertion sequence binding
IUJ48_RS26270	COG2864	formate dehydrogenase
IUJ48_RS26275	COG0437	4 iron, 4 sulfur cluster binding
IUJ48_RS26290	COG1607	acyl-coa hydrolase
IUJ48_RS26315	COG3064	Membrane
IUJ48_RS26320	COG3585	molybdate ion transport
IUJ48_RS26325	COG1116	anion transmembrane transporter activity
IUJ48_RS26330	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_RS26335	COG2011	ABC-type metal ion transport system permease component
IUJ48_RS26350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS26355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_RS26360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_RS26365	COG0431	NADPH-dependent FMN reductase
IUJ48_RS26370	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_RS26395	COG0747	negative chemotaxis
IUJ48_RS26405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS26435	COG3069	C4-dicarboxylate transmembrane transporter activity
IUJ48_RS26445	COG1802	Transcriptional regulator
IUJ48_RS26505	COG3188	usher protein
IUJ48_RS26520	COG2814	Major facilitator Superfamily
IUJ48_RS26525	COG0840	transmembrane signaling receptor activity
IUJ48_RS26540	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IUJ48_RS26545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IUJ48_RS26555	COG2188	Transcriptional regulator
IUJ48_RS26570	COG0737	Belongs to the 5'-nucleotidase family
IUJ48_RS26620	COG0463	Glycosyl transferase, family 2
IUJ48_RS26625	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IUJ48_RS26635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ48_RS26645	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IUJ48_RS26650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IUJ48_RS26655	COG2423	ornithine cyclodeaminase activity
IUJ48_RS26665	COG0583	DNA-binding transcription factor activity
IUJ48_RS26670	COG2814	Major facilitator Superfamily
IUJ48_RS26675	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IUJ48_RS26680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IUJ48_RS26705	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IUJ48_RS26720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_RS26725	COG1120	ATPase activity
IUJ48_RS26730	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS26735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_RS26740	COG4592	Periplasmic binding protein
IUJ48_RS26745	COG4774	siderophore transport
IUJ48_RS26760	COG2814	Major facilitator Superfamily
IUJ48_RS26770	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IUJ48_RS26790	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS26800	COG2814	Major facilitator Superfamily
IUJ48_RS26805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IUJ48_RS26825	COG1999	signal sequence binding
IUJ48_RS26835	COG1612	heme a metabolic process
IUJ48_RS26855	COG1845	cytochrome c oxidase, subunit III
IUJ48_RS26870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ48_RS26890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ48_RS26915	COG0067	glutamate synthase
IUJ48_RS26915	COG0069	glutamate synthase activity
IUJ48_RS26915	COG0070	glutamate synthase
IUJ48_RS26930	COG1984	allophanate hydrolase subunit 2
IUJ48_RS26945	COG0511	ligase activity, forming carbon-carbon bonds
IUJ48_RS26950	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IUJ48_RS26955	COG0583	DNA-binding transcription factor activity
IUJ48_RS26970	COG0477	Major facilitator Superfamily
IUJ48_RS26980	COG2070	2-Nitropropane dioxygenase
IUJ48_RS26985	COG1127	ABC transporter
IUJ48_RS26990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUJ48_RS26995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUJ48_RS27000	COG2853	Lipoprotein
IUJ48_RS27010	COG1131	(ABC) transporter
IUJ48_RS27015	COG0842	Transport permease protein
IUJ48_RS27025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IUJ48_RS27030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IUJ48_RS27035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IUJ48_RS27040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ48_RS27045	COG0131	Imidazoleglycerol-phosphate dehydratase
IUJ48_RS27050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IUJ48_RS27055	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IUJ48_RS27060	COG0107	imidazoleglycerol-phosphate synthase activity
IUJ48_RS27065	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IUJ48_RS27070	COG0140	phosphoribosyl-ATP diphosphatase activity
IUJ48_RS27075	COG0537	adenosine 5'-monophosphoramidase activity
IUJ48_RS27080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IUJ48_RS27100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_RS27105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IUJ48_RS27110	COG1970	mechanosensitive ion channel activity
IUJ48_RS27115	COG0723	plastoquinol--plastocyanin reductase activity
IUJ48_RS27120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IUJ48_RS27125	COG2857	Cytochrome c1
IUJ48_RS27130	COG0625	glutathione transferase activity
IUJ48_RS27135	COG2969	positive regulation of protein catabolic process
IUJ48_RS27165	COG0583	DNA-binding transcription factor activity
IUJ48_RS27175	COG1104	cysteine desulfurase activity
IUJ48_RS27185	COG3708	Transcriptional regulator
IUJ48_RS27185	COG2207	Transcriptional regulator
IUJ48_RS27195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IUJ48_RS27200	COG0747	negative chemotaxis
IUJ48_RS27205	COG0601	transmembrane transport
IUJ48_RS27210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS27220	COG1228	amidohydrolase
IUJ48_RS27225	COG5339	Protein conserved in bacteria
IUJ48_RS27230	COG5339	Protein conserved in bacteria
IUJ48_RS27235	COG0513	Belongs to the DEAD box helicase family
IUJ48_RS27240	COG1280	lysine exporter protein (LysE YggA)
IUJ48_RS27245	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IUJ48_RS27265	COG0583	DNA-binding transcription factor activity
IUJ48_RS27285	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IUJ48_RS27300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ48_RS27310	COG1609	Transcriptional regulator
IUJ48_RS27315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ48_RS27325	COG1653	transport
IUJ48_RS27330	COG1175	transmembrane transport
IUJ48_RS27335	COG0395	ABC-type sugar transport system, permease component
IUJ48_RS27350	COG0018	arginyl-trna synthetase
IUJ48_RS27360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ48_RS27385	COG1280	lysine exporter protein (LysE YggA)
IUJ48_RS27400	COG1742	UPF0060 membrane protein
IUJ48_RS27410	COG1473	amidohydrolase
IUJ48_RS27415	COG1960	acyl-CoA dehydrogenase activity
IUJ48_RS27420	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
IUJ48_RS27425	COG0183	Belongs to the thiolase family
IUJ48_RS27430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IUJ48_RS27480	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS27495	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS27500	COG1595	DNA-templated transcription, initiation
IUJ48_RS27515	COG2814	Major facilitator Superfamily
IUJ48_RS27520	COG2186	Transcriptional regulator
IUJ48_RS27550	COG3339	Conserved Protein
IUJ48_RS27560	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
IUJ48_RS27570	COG2814	Major facilitator Superfamily
IUJ48_RS27595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IUJ48_RS27600	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS27605	COG3422	double-strand break repair
IUJ48_RS27610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS27615	COG0765	amino acid transport
IUJ48_RS27620	COG0765	amino acid transport
IUJ48_RS27640	COG2358	TRAP transporter, solute receptor (TAXI family
IUJ48_RS27650	COG2922	Belongs to the Smg family
IUJ48_RS27655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ48_RS27680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_RS27685	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS27690	COG0028	Belongs to the TPP enzyme family
IUJ48_RS27695	COG1522	sequence-specific DNA binding
IUJ48_RS27700	COG3781	membrane
IUJ48_RS27715	COG2814	Major facilitator Superfamily
IUJ48_RS27730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ48_RS27745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IUJ48_RS27755	COG1744	ABC transporter substrate-binding protein PnrA-like
IUJ48_RS27760	COG3845	ABC transporter
IUJ48_RS27765	COG4603	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS27775	COG0402	S-adenosylhomocysteine deaminase activity
IUJ48_RS27780	COG0251	oxidation-reduction process
IUJ48_RS27805	COG1177	transmembrane transport
IUJ48_RS27810	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_RS27815	COG3842	ATPase activity
IUJ48_RS27825	COG1609	Transcriptional regulator
IUJ48_RS27880	COG1177	transmembrane transport
IUJ48_RS27885	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_RS27890	COG3842	ATPase activity
IUJ48_RS27925	COG1126	abc transporter atp-binding protein
IUJ48_RS27930	COG0765	amino acid transport
IUJ48_RS27935	COG0765	amino acid transport
IUJ48_RS27940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS27945	COG0583	DNA-binding transcription factor activity
IUJ48_RS27955	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IUJ48_RS27980	COG0583	DNA-binding transcription factor activity
IUJ48_RS27985	COG0583	DNA-binding transcription factor activity
IUJ48_RS27990	COG2814	Major facilitator Superfamily
IUJ48_RS28000	COG0592	DNA-directed DNA polymerase activity
IUJ48_RS28005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IUJ48_RS28010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IUJ48_RS28015	COG0594	ribonuclease P activity
IUJ48_RS28020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IUJ48_RS28030	COG0753	catalase activity
IUJ48_RS28035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUJ48_RS28045	COG2175	clavaminate synthase activity
IUJ48_RS28050	COG1473	amidohydrolase
IUJ48_RS28055	COG4608	Belongs to the ABC transporter superfamily
IUJ48_RS28060	COG0444	Belongs to the ABC transporter superfamily
IUJ48_RS28065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_RS28070	COG0601	transmembrane transport
IUJ48_RS28080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IUJ48_RS28095	COG0038	chloride channel
IUJ48_RS28125	COG0436	Aminotransferase
IUJ48_RS28130	COG3180	Ammonia monooxygenase
IUJ48_RS28135	COG1278	Cold shock
IUJ48_RS28140	COG0445	tRNA wobble uridine modification
IUJ48_RS28145	COG0357	Ribosomal RNA small subunit methyltransferase G
IUJ48_RS28150	COG1192	Involved in chromosome partitioning
IUJ48_RS28160	COG1475	DNA binding
IUJ48_RS28165	COG0252	asparaginase activity
IUJ48_RS28170	COG0583	DNA-binding transcription factor activity
IUJ48_RS28195	COG1349	DNA-binding transcription factor activity
IUJ48_RS28205	COG3842	ATPase activity
IUJ48_RS28210	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ48_RS28250	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IUJ48_RS28260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IUJ48_RS28270	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IUJ48_RS28275	COG0081	regulation of translation
IUJ48_RS28280	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IUJ48_RS28285	COG0222	ribosome binding
IUJ48_RS28290	COG0085	RNA polymerase activity
IUJ48_RS28295	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IUJ48_RS28310	COG5002	protein histidine kinase activity
IUJ48_RS28325	COG0745	RESPONSE REGULATOR receiver
IUJ48_RS28330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IUJ48_RS28335	COG0049	tRNA binding
IUJ48_RS28340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IUJ48_RS28345	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IUJ48_RS28350	COG0051	transcription antitermination factor activity, RNA binding
IUJ48_RS28355	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IUJ48_RS28365	COG0089	rRNA binding
IUJ48_RS28370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IUJ48_RS28375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IUJ48_RS28380	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IUJ48_RS28385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IUJ48_RS28390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IUJ48_RS28395	COG0255	Belongs to the universal ribosomal protein uL29 family
IUJ48_RS28400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IUJ48_RS28440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ48_RS28455	COG2169	Transcriptional regulator
IUJ48_RS28455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ48_RS28470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IUJ48_RS28475	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IUJ48_RS28480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IUJ48_RS28485	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IUJ48_RS28490	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IUJ48_RS28495	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IUJ48_RS28500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IUJ48_RS28505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IUJ48_RS28510	COG1841	ribosomal large subunit assembly
IUJ48_RS28515	COG0200	Binds to the 23S rRNA
IUJ48_RS28520	COG0201	protein transport
IUJ48_RS28525	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IUJ48_RS28530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IUJ48_RS28535	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IUJ48_RS28540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IUJ48_RS28545	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IUJ48_RS28550	COG0202	RNA polymerase activity
IUJ48_RS28555	COG0203	ribosomal protein L17
IUJ48_RS28565	COG1324	tolerance protein
IUJ48_RS28570	COG4232	protein-disulfide reductase activity
IUJ48_RS28585	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IUJ48_RS28595	COG1333	cytochrome c biogenesis protein
IUJ48_RS28600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ48_RS28605	COG0019	diaminopimelate decarboxylase activity
IUJ48_RS28615	COG1965	Belongs to the frataxin family
IUJ48_RS28625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IUJ48_RS28630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IUJ48_RS28635	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IUJ48_RS28640	COG0625	glutathione transferase activity
IUJ48_RS28650	COG2814	Major facilitator Superfamily
IUJ48_RS28660	COG4106	trans-aconitate 2-methyltransferase activity
IUJ48_RS28700	COG2186	Transcriptional regulator
IUJ48_RS28715	COG1422	Protein of unknown function (DUF1090)
IUJ48_RS28725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS28730	COG1956	GAF domain-containing protein
IUJ48_RS28735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_RS28750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ48_RS28775	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IUJ48_RS28780	COG3568	Endonuclease Exonuclease Phosphatase
IUJ48_RS28805	COG0697	spore germination
IUJ48_RS28810	COG2814	Major facilitator Superfamily
IUJ48_RS28825	COG0367	asparagine synthase
IUJ48_RS28840	COG2226	methyltransferase
IUJ48_RS28870	COG0175	sulfate reduction
IUJ48_RS28885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IUJ48_RS28895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IUJ48_RS28905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_RS28920	COG0367	asparagine synthase
IUJ48_RS28955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IUJ48_RS28980	COG0859	PFAM glycosyl transferase family 9
IUJ48_RS28995	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IUJ48_RS29005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUJ48_RS29030	COG1686	Belongs to the peptidase S11 family
IUJ48_RS29040	COG2921	Belongs to the UPF0250 family
IUJ48_RS29045	COG0321	lipoyl(octanoyl) transferase activity
IUJ48_RS29060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IUJ48_RS29065	COG2096	Adenosyltransferase
IUJ48_RS29075	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IUJ48_RS29080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IUJ48_RS29090	COG0523	cobalamin synthesis protein
IUJ48_RS29095	COG0735	belongs to the Fur family
IUJ48_RS29110	COG0803	Belongs to the bacterial solute-binding protein 9 family
IUJ48_RS29120	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IUJ48_RS29125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUJ48_RS29135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IUJ48_RS29150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IUJ48_RS29155	COG0154	amidase activity
IUJ48_RS29160	COG0477	Major facilitator Superfamily
IUJ48_RS29170	COG0583	DNA-binding transcription factor activity
IUJ48_RS29185	COG0066	3-isopropylmalate dehydratase activity
IUJ48_RS29200	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS29205	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IUJ48_RS29210	COG1950	PFAM Membrane protein of
IUJ48_RS29230	COG1305	Transglutaminase-like
IUJ48_RS29240	COG2308	Evidence 4 Homologs of previously reported genes of
IUJ48_RS29245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IUJ48_RS29255	COG0617	tRNA 3'-terminal CCA addition
IUJ48_RS29265	COG0513	Belongs to the DEAD box helicase family
IUJ48_RS29270	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IUJ48_RS29280	COG3210	domain, Protein
IUJ48_RS29350	COG0351	phosphomethylpyrimidine kinase
IUJ48_RS29350	COG0352	thiamine-phosphate diphosphorylase activity
IUJ48_RS29350	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IUJ48_RS29355	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS29375	COG3189	MarR family transcriptional regulator
IUJ48_RS29405	COG0640	Transcriptional regulator
IUJ48_RS29465	COG1846	Transcriptional regulator
IUJ48_RS29470	COG1764	response to oxidative stress
IUJ48_RS29495	COG0583	DNA-binding transcription factor activity
IUJ48_RS29505	COG0583	DNA-binding transcription factor activity
IUJ48_RS29515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IUJ48_RS29520	COG0708	Exodeoxyribonuclease III
IUJ48_RS29525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IUJ48_RS29540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IUJ48_RS29545	COG0154	amidase activity
IUJ48_RS29550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IUJ48_RS29555	COG1077	Cell shape determining protein MreB Mrl
IUJ48_RS29560	COG1792	Involved in formation and maintenance of cell shape
IUJ48_RS29570	COG0768	penicillin binding
IUJ48_RS29575	COG0772	Belongs to the SEDS family
IUJ48_RS29580	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IUJ48_RS29585	COG0471	metal ion transport
IUJ48_RS29590	COG1309	transcriptional regulator
IUJ48_RS29600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IUJ48_RS29605	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_RS29610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_RS29620	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IUJ48_RS29625	COG0792	nuclease activity
IUJ48_RS29635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ48_RS29645	COG1660	Displays ATPase and GTPase activities
IUJ48_RS29660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS29665	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IUJ48_RS29675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IUJ48_RS29680	COG1137	ATPase activity
IUJ48_RS29695	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IUJ48_RS29705	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IUJ48_RS29720	COG1294	oxidase, subunit
IUJ48_RS29730	COG4988	ABC transporter
IUJ48_RS29735	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IUJ48_RS29740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IUJ48_RS29755	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_RS29760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ48_RS29765	COG1238	metal cluster binding
IUJ48_RS29780	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS29785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IUJ48_RS29790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_RS29795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS29810	COG0758	DNA mediated transformation
IUJ48_RS29815	COG0242	peptide deformylase activity
IUJ48_RS29820	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IUJ48_RS29830	COG0546	phosphoglycolate phosphatase activity
IUJ48_RS29850	COG1733	regulation of RNA biosynthetic process
IUJ48_RS29860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IUJ48_RS29865	COG1280	lysine exporter protein (LysE YggA)
IUJ48_RS29870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IUJ48_RS29870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ48_RS29880	COG5000	phosphorelay sensor kinase activity
IUJ48_RS29885	COG2204	response regulator
IUJ48_RS29890	COG0569	domain protein
IUJ48_RS29895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IUJ48_RS29900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IUJ48_RS29905	COG2226	methyltransferase
IUJ48_RS29910	COG1040	competence protein
IUJ48_RS29920	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_RS29925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IUJ48_RS29930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IUJ48_RS29935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ48_RS29945	COG0588	phosphoglycerate mutase activity
IUJ48_RS29950	COG4942	peptidase
IUJ48_RS29955	COG0793	Belongs to the peptidase S41A family
IUJ48_RS29960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IUJ48_RS29965	COG5001	Diguanylate cyclase
IUJ48_RS29965	COG5002	protein histidine kinase activity
IUJ48_RS29965	COG3447	MASE1 domain protein
IUJ48_RS29970	COG2186	Transcriptional regulator
IUJ48_RS29980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IUJ48_RS29985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ48_RS30000	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IUJ48_RS30005	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IUJ48_RS30010	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IUJ48_RS30015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IUJ48_RS30020	COG0142	geranyltranstransferase activity
IUJ48_RS30030	COG0489	protein tyrosine kinase activity
IUJ48_RS30085	COG0551	DNA topoisomerase type I activity
IUJ48_RS30085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IUJ48_RS30140	COG2433	Pfam Transposase IS66
IUJ48_RS30165	COG0659	secondary active sulfate transmembrane transporter activity
IUJ48_RS30170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ48_RS30185	COG0459	protein refolding
IUJ48_RS30195	COG1185	polyribonucleotide nucleotidyltransferase activity
IUJ48_RS30210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IUJ48_RS30215	COG0659	secondary active sulfate transmembrane transporter activity
IUJ48_RS30220	COG0589	response to stress
IUJ48_RS30230	COG0438	transferase activity, transferring glycosyl groups
IUJ48_RS30240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_RS30245	COG0785	Cytochrome C biogenesis protein
IUJ48_RS30280	COG3220	belongs to the UPF0276 family
IUJ48_RS30310	COG0789	Transcriptional regulator
IUJ48_RS30320	COG2608	mercury ion transmembrane transporter activity
IUJ48_RS30325	COG2608	mercury ion transmembrane transporter activity
IUJ48_RS30330	COG0789	Transcriptional regulator
IUJ48_RS30345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IUJ48_RS30350	COG4654	Cytochrome c, class I
IUJ48_RS30370	COG4191	Histidine kinase
IUJ48_RS30395	COG0431	NADPH-dependent FMN reductase
IUJ48_RS30425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IUJ48_RS30430	COG0573	inorganic phosphate transmembrane transporter activity
IUJ48_RS30435	COG0581	inorganic phosphate transmembrane transporter activity
IUJ48_RS30440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IUJ48_RS30450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IUJ48_RS30465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IUJ48_RS30540	COG3133	Outer membrane lipoprotein
IUJ48_RS30580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUJ48_RS30605	COG2948	multi-organism process
IUJ48_RS30640	COG3451	type IV secretory pathway VirB4
IUJ48_RS30760	COG0235	Class ii aldolase
IUJ48_RS30765	COG3622	Belongs to the hyi family
IUJ48_RS30770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_RS30775	COG2084	Dehydrogenase
IUJ48_RS30780	COG3395	kinase activity
IUJ48_RS30785	COG2186	Transcriptional regulator
IUJ48_RS30790	COG0583	DNA-binding transcription factor activity
IUJ48_RS30810	COG3622	Belongs to the hyi family
IUJ48_RS30830	COG1522	sequence-specific DNA binding
IUJ48_RS30835	COG1280	lysine exporter protein (LysE YggA)
IUJ48_RS30850	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IUJ48_RS30855	COG2890	protein-(glutamine-N5) methyltransferase activity
IUJ48_RS30860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUJ48_RS30875	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_RS30895	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_RS30920	COG0477	Major facilitator Superfamily
IUJ48_RS30925	COG0583	DNA-binding transcription factor activity
IUJ48_RS30935	COG0583	DNA-binding transcription factor activity
IUJ48_RS30950	COG0625	glutathione transferase activity
IUJ48_RS30955	COG1053	succinate dehydrogenase
IUJ48_RS30965	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS30985	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_RS30995	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS31000	COG1802	Transcriptional regulator
IUJ48_RS31005	COG0288	reversible hydration of carbon dioxide
IUJ48_RS31025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ48_RS31035	COG4829	muconolactone delta-isomerase
IUJ48_RS31040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ48_RS31050	COG1414	Transcriptional regulator
IUJ48_RS31055	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS31060	COG2031	fatty acid transporter
IUJ48_RS31065	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_RS31070	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IUJ48_RS31075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IUJ48_RS31080	COG2200	EAL domain
IUJ48_RS31095	COG0583	DNA-binding transcription factor activity
IUJ48_RS31100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ48_RS31110	COG0129	dihydroxy-acid dehydratase activity
IUJ48_RS31115	COG0583	DNA-binding transcription factor activity
IUJ48_RS31120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ48_RS31125	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ48_RS31135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IUJ48_RS31140	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS31145	COG0410	ABC transporter
IUJ48_RS31170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IUJ48_RS31180	COG2186	Transcriptional regulator
IUJ48_RS31190	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IUJ48_RS31210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_RS31215	COG0583	DNA-binding transcription factor activity
IUJ48_RS31220	COG0628	permease
IUJ48_RS31240	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_RS31245	COG3842	ATPase activity
IUJ48_RS31255	COG0277	FAD linked oxidase domain protein
IUJ48_RS31270	COG0477	Major facilitator Superfamily
IUJ48_RS31285	COG1695	Transcriptional regulator
IUJ48_RS31295	COG0583	DNA-binding transcription factor activity
IUJ48_RS31315	COG5002	protein histidine kinase activity
IUJ48_RS31315	COG2198	Histidine kinase
IUJ48_RS31315	COG0784	Response regulator, receiver
IUJ48_RS31425	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_RS31435	COG3246	L-lysine catabolic process to acetate
IUJ48_RS31440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_RS31445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_RS31460	COG2233	PERMEase
IUJ48_RS31470	COG0326	Molecular chaperone. Has ATPase activity
IUJ48_RS31475	COG2814	Major facilitator Superfamily
IUJ48_RS31480	COG4774	siderophore transport