locus-tag	class	description
ACIN_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACIN_RS00010	COG0592	DNA-directed DNA polymerase activity
ACIN_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACIN_RS00030	COG0187	DNA topoisomerase II activity
ACIN_RS00040	COG0730	response to heat
ACIN_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACIN_RS00055	COG2801	Transposase and inactivated derivatives
ACIN_RS00100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACIN_RS00105	COG0436	Aminotransferase
ACIN_RS00115	COG0489	protein tyrosine kinase activity
ACIN_RS00125	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ACIN_RS00135	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACIN_RS00140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACIN_RS00145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACIN_RS00150	COG1605	Chorismate mutase
ACIN_RS00150	COG0077	Prephenate dehydratase
ACIN_RS00160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACIN_RS00165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACIN_RS00175	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACIN_RS00185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ACIN_RS00185	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ACIN_RS00190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ACIN_RS00200	COG0583	DNA-binding transcription factor activity
ACIN_RS00205	COG0028	Belongs to the TPP enzyme family
ACIN_RS00225	COG0542	response to heat
ACIN_RS00235	COG0710	3-dehydroquinate dehydratase activity
ACIN_RS00240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACIN_RS00245	COG0668	transmembrane transport
ACIN_RS00250	COG2379	hydroxypyruvate reductase
ACIN_RS00295	COG2358	TRAP transporter, solute receptor (TAXI family
ACIN_RS00350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACIN_RS00375	COG3189	MarR family transcriptional regulator
ACIN_RS00385	COG1115	amino acid carrier protein
ACIN_RS00390	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACIN_RS00395	COG0740	serine-type endopeptidase activity
ACIN_RS00400	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACIN_RS00405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACIN_RS00415	COG0494	nUDIX hydrolase
ACIN_RS00420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACIN_RS00435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACIN_RS00440	COG2860	membrane
ACIN_RS00450	COG1666	GTP binding
ACIN_RS00460	COG0556	nucleotide-excision repair
ACIN_RS00470	COG0322	excinuclease ABC activity
ACIN_RS00475	COG1773	rubredoxin
ACIN_RS00480	COG0561	phosphatase activity
ACIN_RS00485	COG1660	Displays ATPase and GTPase activities
ACIN_RS00490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ACIN_RS00530	COG0440	acetolactate synthase activity
ACIN_RS00535	COG0028	Belongs to the TPP enzyme family
ACIN_RS00540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACIN_RS00550	COG0385	Bile acid
ACIN_RS00555	COG0129	dihydroxy-acid dehydratase activity
ACIN_RS00570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACIN_RS00580	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACIN_RS00585	COG1121	(ABC) transporter
ACIN_RS00590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACIN_RS00605	COG0583	DNA-binding transcription factor activity
ACIN_RS00610	COG2851	Citrate transporter
ACIN_RS00680	COG1288	antiporter activity
ACIN_RS00690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACIN_RS00700	COG1691	(AIR) carboxylase
ACIN_RS00735	COG1971	Probably functions as a manganese efflux pump
ACIN_RS00740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACIN_RS00745	COG0482	sulfurtransferase activity
ACIN_RS00760	COG0360	Binds together with S18 to 16S ribosomal RNA
ACIN_RS00765	COG0629	single-stranded DNA binding
ACIN_RS00770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACIN_RS00785	COG1131	(ABC) transporter
ACIN_RS00790	COG0842	Transport permease protein
ACIN_RS00795	COG0842	Transport permease protein
ACIN_RS00805	COG0583	DNA-binding transcription factor activity
ACIN_RS00815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACIN_RS00825	COG2706	6-phosphogluconolactonase activity
ACIN_RS00830	COG5016	pyruvate
ACIN_RS00830	COG0511	ligase activity, forming carbon-carbon bonds
ACIN_RS00840	COG1122	ATPase activity
ACIN_RS00845	COG1122	ATPase activity
ACIN_RS00860	COG1269	ATP hydrolysis coupled proton transport
ACIN_RS00865	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACIN_RS00880	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
ACIN_RS00885	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ACIN_RS00890	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
ACIN_RS00895	COG1394	ATPase activity, coupled to movement of substances
ACIN_RS00915	COG0745	RESPONSE REGULATOR receiver
ACIN_RS00920	COG5002	protein histidine kinase activity
ACIN_RS00920	COG5000	phosphorelay sensor kinase activity
ACIN_RS00930	COG3885	ferrous iron binding
ACIN_RS00930	COG2078	PFAM AMMECR1 domain protein
ACIN_RS00935	COG1573	uracil-dna glycosylase
ACIN_RS00955	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACIN_RS00955	COG2878	Part of a membrane complex involved in electron transport
ACIN_RS00960	COG4657	Part of a membrane complex involved in electron transport
ACIN_RS00965	COG4660	Part of a membrane complex involved in electron transport
ACIN_RS00970	COG4659	FMN binding
ACIN_RS00975	COG4658	electron transport chain
ACIN_RS00980	COG4656	Part of a membrane complex involved in electron transport
ACIN_RS00990	COG0791	NLP P60 protein
ACIN_RS00995	COG2204	response regulator
ACIN_RS01000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACIN_RS01005	COG0772	Belongs to the SEDS family
ACIN_RS01010	COG0768	penicillin binding
ACIN_RS01015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACIN_RS01025	COG0318	PFAM AMP-dependent synthetase and ligase
ACIN_RS01050	COG1966	Carbon starvation protein
ACIN_RS01055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACIN_RS01060	COG3047	cAMP biosynthetic process
ACIN_RS01060	COG2885	chlorophyll binding
ACIN_RS01065	COG0277	FAD linked oxidase domain protein
ACIN_RS01070	COG0405	Gamma-glutamyltransferase
ACIN_RS01075	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACIN_RS01080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACIN_RS01100	COG2084	Dehydrogenase
ACIN_RS01110	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACIN_RS01115	COG3842	ATPase activity
ACIN_RS01120	COG0251	oxidation-reduction process
ACIN_RS01135	COG2801	Transposase and inactivated derivatives
ACIN_RS01150	COG0010	Belongs to the arginase family
ACIN_RS01155	COG1414	Transcriptional regulator
ACIN_RS01175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACIN_RS01190	COG1704	LemA family
ACIN_RS01220	COG2801	Transposase and inactivated derivatives
ACIN_RS01240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACIN_RS01245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACIN_RS01250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACIN_RS01260	COG1136	(ABC) transporter
ACIN_RS01265	COG0577	efflux transmembrane transporter activity
ACIN_RS01265	COG1136	(ABC) transporter
ACIN_RS01270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ACIN_RS01275	COG1914	H( )-stimulated, divalent metal cation uptake system
ACIN_RS01280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ACIN_RS01285	COG1984	allophanate hydrolase subunit 2
ACIN_RS01295	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ACIN_RS01305	COG1194	a g-specific adenine glycosylase
ACIN_RS01310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACIN_RS01320	COG2116	formate transmembrane transporter activity
ACIN_RS01345	COG3829	transcription factor binding
ACIN_RS01350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACIN_RS01355	COG2986	histidine ammonia-lyase
ACIN_RS01360	COG2056	Na+-H+ antiporter family
ACIN_RS01370	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACIN_RS01390	COG2172	sigma factor antagonist activity
ACIN_RS01405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACIN_RS01415	COG4770	biotin carboxylase activity
ACIN_RS01420	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ACIN_RS01450	COG2003	Belongs to the UPF0758 family
ACIN_RS01455	COG1077	Cell shape determining protein MreB Mrl
ACIN_RS01475	COG0772	Belongs to the SEDS family
ACIN_RS01490	COG1530	ribonuclease E activity
ACIN_RS01495	COG0617	tRNA 3'-terminal CCA addition
ACIN_RS01500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACIN_RS01505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACIN_RS01510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACIN_RS01515	COG1924	4 iron, 4 sulfur cluster binding
ACIN_RS01520	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ACIN_RS01525	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ACIN_RS01530	COG1328	CTP reductase activity
ACIN_RS01540	COG1473	amidohydrolase
ACIN_RS01555	COG1607	acyl-coa hydrolase
ACIN_RS01565	COG0733	neurotransmitter:sodium symporter activity
ACIN_RS01575	COG0561	phosphatase activity
ACIN_RS01580	COG2707	UPF0756 membrane protein
ACIN_RS01585	COG1376	ErfK ybiS ycfS ynhG family protein
ACIN_RS01595	COG0735	belongs to the Fur family
ACIN_RS01600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACIN_RS01610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACIN_RS01615	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACIN_RS01625	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACIN_RS01630	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ACIN_RS01635	COG2801	Transposase and inactivated derivatives
ACIN_RS01645	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACIN_RS01650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACIN_RS01655	COG0242	peptide deformylase activity
ACIN_RS01660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACIN_RS01670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACIN_RS01670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACIN_RS01675	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACIN_RS01680	COG0631	protein serine/threonine phosphatase activity
ACIN_RS01685	COG0515	serine threonine protein kinase
ACIN_RS01685	COG2815	serine threonine protein kinase
ACIN_RS01695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACIN_RS01715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACIN_RS01715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACIN_RS01725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACIN_RS01730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACIN_RS01745	COG1418	mRNA catabolic process
ACIN_RS01760	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ACIN_RS01775	COG1151	hydroxylamine reductase activity
ACIN_RS01800	COG2610	gluconate transmembrane transporter activity
ACIN_RS01805	COG0396	ATPase activity
ACIN_RS01810	COG0719	Fe-S assembly protein
ACIN_RS01820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACIN_RS01825	COG0822	iron-sulfur transferase activity
ACIN_RS01830	COG1185	polyribonucleotide nucleotidyltransferase activity
ACIN_RS01835	COG2190	(PTS) system
ACIN_RS01835	COG1263	PTS System
ACIN_RS01835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACIN_RS01845	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACIN_RS01850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACIN_RS01860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACIN_RS01870	COG0351	phosphomethylpyrimidine kinase
ACIN_RS01875	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ACIN_RS01880	COG0352	thiamine-phosphate diphosphorylase activity
ACIN_RS01890	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ACIN_RS01895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACIN_RS01900	COG0228	four-way junction DNA binding
ACIN_RS01915	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACIN_RS01920	COG0336	Belongs to the RNA methyltransferase TrmD family
ACIN_RS01925	COG0335	large ribosomal subunit rRNA binding
ACIN_RS01935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ACIN_RS01940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACIN_RS01945	COG0792	nuclease activity
ACIN_RS01975	COG0572	uridine kinase
ACIN_RS01980	COG0436	Aminotransferase
ACIN_RS01995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACIN_RS02005	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACIN_RS02010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACIN_RS02050	COG1122	ATPase activity
ACIN_RS02060	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACIN_RS02065	COG0101	tRNA pseudouridine synthase activity
ACIN_RS02070	COG4771	TonB-dependent receptor
ACIN_RS02080	COG1121	(ABC) transporter
ACIN_RS02085	COG0811	peptide transport
ACIN_RS02110	COG1268	BioY protein
ACIN_RS02115	COG0183	Belongs to the thiolase family
ACIN_RS02135	COG1720	tRNA m6t6A37 methyltransferase activity
ACIN_RS02155	COG2731	YhcH YjgK YiaL family protein
ACIN_RS02195	COG0583	DNA-binding transcription factor activity
ACIN_RS02200	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACIN_RS02205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACIN_RS02215	COG0602	queuosine metabolic process
ACIN_RS02235	COG4948	Mandelate Racemase Muconate Lactonizing
ACIN_RS02255	COG3584	3D domain protein
ACIN_RS02255	COG1388	LysM domain
ACIN_RS02265	COG1960	acyl-CoA dehydrogenase activity
ACIN_RS02275	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACIN_RS02285	COG1214	PFAM Peptidase M22, glycoprotease
ACIN_RS02300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACIN_RS02305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACIN_RS02315	COG1979	alcohol dehydrogenase
ACIN_RS02320	COG0426	domain, Protein
ACIN_RS02325	COG1960	acyl-CoA dehydrogenase activity
ACIN_RS02350	COG0024	Methionine aminopeptidase
ACIN_RS02365	COG2252	PERMEase
ACIN_RS02370	COG0037	tRNA processing
ACIN_RS02380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACIN_RS02395	COG1966	Carbon starvation protein
ACIN_RS02400	COG0039	L-malate dehydrogenase activity
ACIN_RS02405	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACIN_RS02415	COG3875	lactate racemase activity
ACIN_RS02435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACIN_RS02440	COG1702	phosphate starvation-inducible protein PhoH
ACIN_RS02445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACIN_RS02455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACIN_RS02460	COG1253	flavin adenine dinucleotide binding
ACIN_RS02475	COG0708	Exodeoxyribonuclease III
ACIN_RS02485	COG0494	nUDIX hydrolase
ACIN_RS02495	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACIN_RS02505	COG0495	leucyl-tRNA aminoacylation
ACIN_RS02510	COG1596	polysaccharide export
ACIN_RS02510	COG1555	photosystem II stabilization
ACIN_RS02515	COG2333	competence protein COMEC
ACIN_RS02515	COG0658	competence protein
ACIN_RS02525	COG0786	glutamate:sodium symporter activity
ACIN_RS02540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACIN_RS02545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACIN_RS02550	COG1802	Transcriptional regulator
ACIN_RS02555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACIN_RS02560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACIN_RS02565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACIN_RS02580	COG1760	l-serine dehydratase
ACIN_RS02585	COG1760	l-serine dehydratase
ACIN_RS02590	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ACIN_RS02600	COG0254	rRNA binding
ACIN_RS02605	COG3872	metal-dependent enzyme
ACIN_RS02610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACIN_RS02615	COG2890	protein-(glutamine-N5) methyltransferase activity
ACIN_RS02620	COG0009	L-threonylcarbamoyladenylate synthase
ACIN_RS02625	COG0698	ribose 5-phosphate isomerase
ACIN_RS02630	COG4475	Protein of unknown function (DUF436)
ACIN_RS02635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACIN_RS02640	COG2131	deaminase
ACIN_RS02655	COG0473	3-isopropylmalate dehydrogenase activity
ACIN_RS02675	COG0589	response to stress
ACIN_RS02680	COG0589	response to stress
ACIN_RS02685	COG0589	response to stress
ACIN_RS02690	COG0589	response to stress
ACIN_RS02695	COG0525	valine-tRNA ligase activity
ACIN_RS02700	COG0285	dihydrofolate synthase activity
ACIN_RS02720	COG3052	prosthetic group binding
ACIN_RS02725	COG0583	DNA-binding transcription factor activity
ACIN_RS02735	COG2851	Citrate transporter
ACIN_RS02755	COG1177	transmembrane transport
ACIN_RS02760	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACIN_RS02785	COG1733	regulation of RNA biosynthetic process
ACIN_RS02795	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACIN_RS02815	COG1288	antiporter activity
ACIN_RS02820	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACIN_RS02830	COG0583	DNA-binding transcription factor activity
ACIN_RS02840	COG2706	6-phosphogluconolactonase activity
ACIN_RS02850	COG0583	DNA-binding transcription factor activity
ACIN_RS02860	COG0778	Nitroreductase
ACIN_RS02875	COG0583	DNA-binding transcription factor activity
ACIN_RS02885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACIN_RS02890	COG1846	Transcriptional regulator
ACIN_RS02900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACIN_RS02915	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACIN_RS02920	COG1304	FMN binding
ACIN_RS02930	COG3314	Sporulation integral membrane protein YlbJ
ACIN_RS02935	COG1414	Transcriptional regulator
ACIN_RS02940	COG3314	Sporulation integral membrane protein YlbJ
ACIN_RS02950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACIN_RS02950	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACIN_RS02970	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACIN_RS02975	COG1132	(ABC) transporter
ACIN_RS02980	COG1663	tetraacyldisaccharide 4'-kinase activity
ACIN_RS02985	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ACIN_RS02990	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACIN_RS03000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACIN_RS03020	COG1137	ATPase activity
ACIN_RS03035	COG4443	Transcriptional Coactivator p15 (PC4)
ACIN_RS03040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACIN_RS03050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACIN_RS03050	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ACIN_RS03055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACIN_RS03060	COG1490	D-aminoacyl-tRNA deacylase activity
ACIN_RS03070	COG0628	permease
ACIN_RS03075	COG0124	histidyl-tRNA synthetase
ACIN_RS03080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACIN_RS03085	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACIN_RS03090	COG0564	pseudouridine synthase activity
ACIN_RS03095	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACIN_RS03100	COG1196	nuclear chromosome segregation
ACIN_RS03105	COG0552	protein localization to endoplasmic reticulum
ACIN_RS03115	COG3118	belongs to the thioredoxin family
ACIN_RS03125	COG2968	Membrane
ACIN_RS03130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACIN_RS03140	COG3468	outer membrane autotransporter barrel domain protein
ACIN_RS03160	COG3468	outer membrane autotransporter barrel domain protein
ACIN_RS03225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACIN_RS03230	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACIN_RS03240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACIN_RS03245	COG0640	Transcriptional regulator
ACIN_RS03255	COG2814	Major facilitator Superfamily
ACIN_RS03270	COG2226	methyltransferase
ACIN_RS03275	COG1191	sigma factor activity
ACIN_RS03300	COG1484	DNA-dependent DNA replication
ACIN_RS03315	COG2814	Major facilitator Superfamily
ACIN_RS03330	COG1846	Transcriptional regulator
ACIN_RS03335	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACIN_RS03345	COG2848	UPF0210 protein
ACIN_RS03350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACIN_RS03365	COG2207	Transcriptional regulator
ACIN_RS03385	COG1115	amino acid carrier protein
ACIN_RS03390	COG1473	amidohydrolase
ACIN_RS03400	COG0183	Belongs to the thiolase family
ACIN_RS03410	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACIN_RS03415	COG1024	Enoyl-CoA hydratase
ACIN_RS03420	COG1362	aminopeptidase activity
ACIN_RS03425	COG1012	belongs to the aldehyde dehydrogenase family
ACIN_RS03440	COG1739	Uncharacterized protein family UPF0029
ACIN_RS03455	COG2990	Protein conserved in bacteria
ACIN_RS03465	COG0497	DNA recombination
ACIN_RS03470	COG0497	DNA recombination
ACIN_RS03485	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ACIN_RS03495	COG2964	Protein conserved in bacteria
ACIN_RS03510	COG0488	(ABC) transporter
ACIN_RS03550	COG1592	Rubrerythrin
ACIN_RS03565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACIN_RS03565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACIN_RS03580	COG0217	transcriptional regulatory protein
ACIN_RS03585	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACIN_RS03590	COG0632	four-way junction helicase activity
ACIN_RS03595	COG2255	four-way junction helicase activity
ACIN_RS03600	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACIN_RS03605	COG2385	sporulation resulting in formation of a cellular spore
ACIN_RS03610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACIN_RS03620	COG1862	Preprotein translocase
ACIN_RS03630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACIN_RS03635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACIN_RS03660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACIN_RS03665	COG0736	holo-[acyl-carrier-protein] synthase activity
ACIN_RS03670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACIN_RS03670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACIN_RS03685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACIN_RS03695	COG0018	arginyl-trna synthetase
ACIN_RS03700	COG0504	CTP synthase activity
ACIN_RS03705	COG1494	fructose-1,6-bisphosphatase
ACIN_RS03710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACIN_RS03715	COG2244	polysaccharide biosynthetic process
ACIN_RS03720	COG3956	TIGRFAM MazG family protein
ACIN_RS03725	COG0776	regulation of translation
ACIN_RS03735	COG1098	S1 RNA binding domain
ACIN_RS03740	COG0037	tRNA processing
ACIN_RS03750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACIN_RS03755	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ACIN_RS03755	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ACIN_RS03765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACIN_RS03775	COG2217	Heavy metal translocating P-type atpase
ACIN_RS03780	COG4771	TonB-dependent receptor
ACIN_RS03785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACIN_RS03790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACIN_RS03795	COG1120	ATPase activity
ACIN_RS03810	COG1132	(ABC) transporter
ACIN_RS03815	COG0811	peptide transport
ACIN_RS03835	COG4771	TonB-dependent receptor
ACIN_RS03865	COG2203	Gaf domain
ACIN_RS03865	COG3706	GGDEF domain
ACIN_RS03865	COG4251	negative regulation of phosphorylation
ACIN_RS03865	COG5001	Diguanylate cyclase
ACIN_RS03895	COG0726	polysaccharide deacetylase
ACIN_RS03920	COG3384	dioxygenase
ACIN_RS03925	COG1733	regulation of RNA biosynthetic process
ACIN_RS03930	COG1304	FMN binding
ACIN_RS03935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACIN_RS03940	COG0569	domain protein
ACIN_RS03945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACIN_RS03950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACIN_RS03955	COG1937	Protein conserved in bacteria
ACIN_RS03980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACIN_RS03985	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACIN_RS03985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACIN_RS03990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACIN_RS03995	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACIN_RS04010	COG4443	Transcriptional Coactivator p15 (PC4)
ACIN_RS04015	COG4372	Transposase
ACIN_RS04030	COG1496	oxidoreductase activity
ACIN_RS04035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACIN_RS04040	COG1799	cell septum assembly
ACIN_RS04045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACIN_RS04060	COG1196	nuclear chromosome segregation
ACIN_RS04090	COG1464	Belongs to the NlpA lipoprotein family
ACIN_RS04095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACIN_RS04100	COG0531	amino acid
ACIN_RS04105	COG1362	aminopeptidase activity
ACIN_RS04110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACIN_RS04145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACIN_RS04150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACIN_RS04155	COG0786	glutamate:sodium symporter activity
ACIN_RS04165	COG1823	symporter activity
ACIN_RS04180	COG1136	(ABC) transporter
ACIN_RS04190	COG1785	Belongs to the alkaline phosphatase family
ACIN_RS04200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACIN_RS04205	COG2011	ABC-type metal ion transport system permease component
ACIN_RS04210	COG4496	protein, YerC YecD
ACIN_RS04215	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ACIN_RS04230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACIN_RS04240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACIN_RS04250	COG0107	imidazoleglycerol-phosphate synthase activity
ACIN_RS04255	COG0140	phosphoribosyl-ATP diphosphatase activity
ACIN_RS04255	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACIN_RS04260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACIN_RS04275	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACIN_RS04280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACIN_RS04285	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACIN_RS04290	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ACIN_RS04295	COG1970	mechanosensitive ion channel activity
ACIN_RS04300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACIN_RS04305	COG0427	acetyl-CoA hydrolase
ACIN_RS04310	COG0494	nUDIX hydrolase
ACIN_RS04315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACIN_RS04320	COG0826	peptidase U32
ACIN_RS04325	COG1193	negative regulation of DNA recombination
ACIN_RS04330	COG0268	Binds directly to 16S ribosomal RNA
ACIN_RS04335	COG0481	GTPase activity
ACIN_RS04345	COG3273	potassium ion transport
ACIN_RS04345	COG0471	metal ion transport
ACIN_RS04350	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACIN_RS04355	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACIN_RS04365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACIN_RS04375	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACIN_RS04380	COG0443	Heat shock 70 kDa protein
ACIN_RS04385	COG0484	heat shock protein binding
ACIN_RS04395	COG0138	bifunctional purine biosynthesis protein purh
ACIN_RS04405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACIN_RS04420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACIN_RS04425	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACIN_RS04430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACIN_RS04440	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACIN_RS04445	COG1923	regulation of RNA biosynthetic process
ACIN_RS04450	COG4974	Belongs to the 'phage' integrase family
ACIN_RS04460	COG0501	Belongs to the peptidase M48B family
ACIN_RS04475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACIN_RS04485	COG0515	serine threonine protein kinase
ACIN_RS04495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACIN_RS04500	COG3481	metal-dependent phosphohydrolase, HD sub domain
ACIN_RS04520	COG4956	integral membrane protein (PIN domain superfamily)
ACIN_RS04525	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACIN_RS04525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACIN_RS04530	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ACIN_RS04530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACIN_RS04535	COG0215	cysteine-tRNA ligase activity
ACIN_RS04540	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ACIN_RS04555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACIN_RS04565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACIN_RS04580	COG0492	ferredoxin-NADP+ reductase activity
ACIN_RS04580	COG3118	belongs to the thioredoxin family
ACIN_RS04585	COG0463	Glycosyl transferase, family 2
ACIN_RS04600	COG4977	sequence-specific DNA binding
ACIN_RS04600	COG1917	Cupin 2, conserved barrel domain protein
ACIN_RS04615	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
ACIN_RS04620	COG1518	maintenance of DNA repeat elements
ACIN_RS04625	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ACIN_RS04670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACIN_RS04675	COG0072	phenylalanine-tRNA ligase activity
ACIN_RS04675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACIN_RS04685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACIN_RS04690	COG0562	UDP-galactopyranose mutase
ACIN_RS04705	COG3475	LICD family
ACIN_RS04715	COG2801	Transposase and inactivated derivatives
ACIN_RS04725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACIN_RS04735	COG3475	LICD family
ACIN_RS04740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACIN_RS04775	COG1088	dTDP-glucose 4,6-dehydratase activity
ACIN_RS04790	COG1442	glycosyl transferase family 8
ACIN_RS04790	COG1216	Glycosyl transferase, family 2
ACIN_RS04795	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ACIN_RS04800	COG1088	dTDP-glucose 4,6-dehydratase activity
ACIN_RS04810	COG1216	Glycosyl transferase, family 2
ACIN_RS04830	COG1309	transcriptional regulator
ACIN_RS04845	COG2852	Protein conserved in bacteria
ACIN_RS04855	COG2852	Protein conserved in bacteria
ACIN_RS04860	COG0540	Belongs to the ATCase OTCase family
ACIN_RS04865	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACIN_RS04870	COG0505	Belongs to the CarA family
ACIN_RS04875	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACIN_RS04880	COG0543	2 iron, 2 sulfur cluster binding
ACIN_RS04885	COG0167	dihydroorotate dehydrogenase activity
ACIN_RS04890	COG0284	orotidine-5'-phosphate decarboxylase activity
ACIN_RS04895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACIN_RS04905	COG1982	Orn Lys Arg decarboxylase major
ACIN_RS04910	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACIN_RS04920	COG1774	PSP1 C-terminal conserved region
ACIN_RS04925	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACIN_RS04930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACIN_RS04935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACIN_RS04935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACIN_RS04940	COG0084	hydrolase, TatD family'
ACIN_RS04945	COG3584	3D domain protein
ACIN_RS04945	COG1388	LysM domain
ACIN_RS04955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACIN_RS04965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACIN_RS04970	COG0459	protein refolding
ACIN_RS04975	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ACIN_RS04985	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ACIN_RS04990	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ACIN_RS04995	COG1228	amidohydrolase
ACIN_RS05005	COG4176	ABC-type proline glycine betaine transport system permease component
ACIN_RS05010	COG0517	IMP dehydrogenase activity
ACIN_RS05010	COG4175	Glycine betaine
ACIN_RS05020	COG0656	L-ascorbic acid biosynthetic process
ACIN_RS05030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACIN_RS05035	COG0573	inorganic phosphate transmembrane transporter activity
ACIN_RS05040	COG0581	inorganic phosphate transmembrane transporter activity
ACIN_RS05045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACIN_RS05050	COG0704	Plays a role in the regulation of phosphate uptake
ACIN_RS05055	COG1687	branched-chain amino acid
ACIN_RS05060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACIN_RS05065	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ACIN_RS05070	COG2852	Protein conserved in bacteria
ACIN_RS05080	COG0534	Mate efflux family protein
ACIN_RS05090	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACIN_RS05095	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACIN_RS05100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACIN_RS05105	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACIN_RS05110	COG0138	bifunctional purine biosynthesis protein purh
ACIN_RS05115	COG0151	Belongs to the GarS family
ACIN_RS05120	COG0516	GMP reductase activity
ACIN_RS05120	COG0517	IMP dehydrogenase activity
ACIN_RS05135	COG2357	RelA SpoT domain protein
ACIN_RS05170	COG5016	pyruvate
ACIN_RS05170	COG0511	ligase activity, forming carbon-carbon bonds
ACIN_RS05185	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACIN_RS05185	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACIN_RS05185	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACIN_RS05185	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACIN_RS05195	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACIN_RS05200	COG0280	phosphate acetyltransferase
ACIN_RS05210	COG3426	butyrate kinase activity
ACIN_RS05215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACIN_RS05225	COG0786	glutamate:sodium symporter activity
ACIN_RS05245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACIN_RS05250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACIN_RS05255	COG1570	exodeoxyribonuclease VII activity
ACIN_RS05260	COG1722	exodeoxyribonuclease VII activity
ACIN_RS05270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACIN_RS05275	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ACIN_RS05280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACIN_RS05290	COG0497	DNA recombination
ACIN_RS05295	COG0494	nUDIX hydrolase
ACIN_RS05300	COG2359	stage V sporulation protein S
ACIN_RS05315	COG1116	anion transmembrane transporter activity
ACIN_RS05320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACIN_RS05350	COG0191	fructose-bisphosphate aldolase activity
ACIN_RS05355	COG0564	pseudouridine synthase activity
ACIN_RS05365	COG0756	dUTP diphosphatase activity
ACIN_RS05375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACIN_RS05380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACIN_RS05385	COG0527	aspartate kinase activity
ACIN_RS05390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACIN_RS05395	COG0613	PHP domain protein
ACIN_RS05405	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACIN_RS05415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACIN_RS05425	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACIN_RS05430	COG1674	ftsk spoiiie
ACIN_RS05435	COG1426	Protein conserved in bacteria
ACIN_RS05440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACIN_RS05445	COG1546	Belongs to the CinA family
ACIN_RS05445	COG1058	Belongs to the CinA family
ACIN_RS05450	COG0513	Belongs to the DEAD box helicase family
ACIN_RS05455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACIN_RS05460	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ACIN_RS05465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACIN_RS05475	COG0402	S-adenosylhomocysteine deaminase activity
ACIN_RS05480	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACIN_RS05490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACIN_RS05515	COG0688	phosphatidylethanolamine metabolic process
ACIN_RS05525	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACIN_RS05535	COG0083	homoserine kinase activity
ACIN_RS05540	COG0460	homoserine dehydrogenase
ACIN_RS05545	COG4492	Belongs to the UPF0735 family
ACIN_RS05555	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACIN_RS05560	COG1160	GTP binding
ACIN_RS05570	COG0539	negative regulation of cytoplasmic translation
ACIN_RS05570	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACIN_RS05580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACIN_RS05585	COG2081	HI0933 family
ACIN_RS05595	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACIN_RS05605	COG1994	Peptidase M50
ACIN_RS05615	COG4974	Belongs to the 'phage' integrase family
ACIN_RS05620	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ACIN_RS05625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACIN_RS05630	COG0758	DNA mediated transformation
ACIN_RS05635	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACIN_RS05640	COG1489	DNA binding
ACIN_RS05650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACIN_RS05670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACIN_RS05675	COG0006	proline dipeptidase activity
ACIN_RS05680	COG0826	peptidase U32
ACIN_RS05685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACIN_RS05690	COG3906	Belongs to the UPF0473 family
ACIN_RS05715	COG0436	Aminotransferase
ACIN_RS05720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACIN_RS05725	COG0473	3-isopropylmalate dehydrogenase activity
ACIN_RS05740	COG0583	DNA-binding transcription factor activity
ACIN_RS05745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACIN_RS05750	COG2033	superoxide reductase activity
ACIN_RS05755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACIN_RS05760	COG0557	exoribonuclease II activity
ACIN_RS05925	COG1783	phage Terminase large subunit
ACIN_RS05950	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ACIN_RS05970	COG3723	Recombinational DNA repair protein, rece pathway
ACIN_RS05975	COG5377	YqaJ viral recombinase family
ACIN_RS06045	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACIN_RS06050	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACIN_RS06055	COG0385	Bile acid
ACIN_RS06060	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACIN_RS06075	COG0604	alcohol dehydrogenase
ACIN_RS06080	COG0251	oxidation-reduction process
ACIN_RS06090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACIN_RS06105	COG1301	dicarboxylic acid transport
ACIN_RS06115	COG0583	DNA-binding transcription factor activity
ACIN_RS06130	COG0583	DNA-binding transcription factor activity
ACIN_RS06135	COG1074	ATP-dependent DNA helicase activity
ACIN_RS06140	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ACIN_RS06145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACIN_RS06150	COG3679	Belongs to the UPF0342 family
ACIN_RS06160	COG5002	protein histidine kinase activity
ACIN_RS06160	COG3850	Histidine kinase
ACIN_RS06165	COG0745	RESPONSE REGULATOR receiver
ACIN_RS06235	COG1690	Belongs to the RtcB family
ACIN_RS06260	COG2801	Transposase and inactivated derivatives
ACIN_RS06265	COG2367	Beta-lactamase
ACIN_RS06315	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACIN_RS06345	COG5301	cellulose 1,4-beta-cellobiosidase activity
ACIN_RS06355	COG3299	homolog of phage Mu protein gp47
ACIN_RS06430	COG0740	serine-type endopeptidase activity
ACIN_RS06435	COG4695	Portal protein
ACIN_RS06520	COG3645	SOS response
ACIN_RS06520	COG3646	Phage regulatory protein
ACIN_RS06570	COG3299	homolog of phage Mu protein gp47
ACIN_RS06660	COG1783	phage Terminase large subunit
ACIN_RS06665	COG5484	DNA packaging
ACIN_RS06665	COG3728	DNA packaging
ACIN_RS06710	COG1061	Type III restriction enzyme res subunit
ACIN_RS06785	COG1773	rubredoxin
ACIN_RS06785	COG1592	Rubrerythrin
ACIN_RS06790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACIN_RS06795	COG2217	Heavy metal translocating P-type atpase
ACIN_RS06820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACIN_RS06825	COG2040	homocysteine
ACIN_RS06830	COG1115	amino acid carrier protein
ACIN_RS06865	COG2801	Transposase and inactivated derivatives
ACIN_RS06875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACIN_RS06875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACIN_RS06875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACIN_RS06880	COG1105	Belongs to the carbohydrate kinase PfkB family
ACIN_RS06895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACIN_RS06910	COG1342	Belongs to the UPF0251 family
ACIN_RS06930	COG2814	Major facilitator Superfamily
ACIN_RS06950	COG0667	Aldo Keto reductase
ACIN_RS06975	COG1131	(ABC) transporter
ACIN_RS06980	COG0667	Aldo Keto reductase
ACIN_RS06995	COG0519	Catalyzes the synthesis of GMP from XMP
ACIN_RS07025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACIN_RS07025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACIN_RS07040	COG0720	synthase
ACIN_RS07045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACIN_RS07055	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACIN_RS07060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACIN_RS07100	COG0583	DNA-binding transcription factor activity
ACIN_RS07105	COG0640	Transcriptional regulator
ACIN_RS07110	COG0346	lactoylglutathione lyase activity
ACIN_RS07120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACIN_RS07135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACIN_RS07150	COG0126	phosphoglycerate kinase activity
ACIN_RS07150	COG0149	triose-phosphate isomerase activity
ACIN_RS07165	COG1301	dicarboxylic acid transport
ACIN_RS07170	COG1741	Belongs to the pirin family
ACIN_RS07180	COG0733	neurotransmitter:sodium symporter activity
ACIN_RS07205	COG0697	spore germination
ACIN_RS07235	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACIN_RS07255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACIN_RS07260	COG1758	RNA polymerase activity
ACIN_RS07265	COG0194	GDP metabolic process
ACIN_RS07270	COG2052	Domain of unknown function (DUF370)
ACIN_RS07275	COG1561	YicC-like family, N-terminal region
ACIN_RS07295	COG2801	Transposase and inactivated derivatives
ACIN_RS07325	COG2165	general secretion pathway protein
ACIN_RS07340	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACIN_RS07345	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACIN_RS07350	COG3856	small basic protein
ACIN_RS07365	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACIN_RS07370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACIN_RS07375	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACIN_RS07380	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACIN_RS07385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACIN_RS07390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACIN_RS07400	COG4839	cell division protein FtsL
ACIN_RS07405	COG0275	rRNA processing
ACIN_RS07410	COG2001	Belongs to the MraZ family
ACIN_RS07425	COG2721	sulfolactate sulfo-lyase activity
ACIN_RS07430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACIN_RS07445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ACIN_RS07455	COG0456	acetyltransferase
ACIN_RS07460	COG1126	abc transporter atp-binding protein
ACIN_RS07465	COG0765	amino acid transport
ACIN_RS07470	COG0765	amino acid transport
ACIN_RS07475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIN_RS07480	COG2079	MmgE PrpD family protein
ACIN_RS07490	COG0622	Phosphoesterase
ACIN_RS07510	COG0534	Mate efflux family protein
ACIN_RS07520	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACIN_RS07525	COG0427	acetyl-CoA hydrolase
ACIN_RS07545	COG0129	dihydroxy-acid dehydratase activity
ACIN_RS07555	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACIN_RS07560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACIN_RS07560	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACIN_RS07570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACIN_RS07575	COG2610	gluconate transmembrane transporter activity
ACIN_RS07580	COG4948	Mandelate Racemase Muconate Lactonizing
ACIN_RS07585	COG0583	DNA-binding transcription factor activity
ACIN_RS07595	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACIN_RS07600	COG0390	transport system, permease component
ACIN_RS07605	COG2801	Transposase and inactivated derivatives
ACIN_RS07620	COG1120	ATPase activity
ACIN_RS07630	COG1473	amidohydrolase
ACIN_RS07640	COG0196	riboflavin kinase activity
ACIN_RS07645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACIN_RS07650	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACIN_RS07655	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACIN_RS07660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACIN_RS07660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACIN_RS07665	COG1358	cellular component organization or biogenesis
ACIN_RS07670	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ACIN_RS07675	COG0195	Participates in both transcription termination and antitermination
ACIN_RS07680	COG0779	Required for maturation of 30S ribosomal subunits
ACIN_RS07695	COG1217	gtp-binding protein TYPA
ACIN_RS07700	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ACIN_RS07730	COG1285	pathogenesis
ACIN_RS07735	COG0442	prolyl-tRNA aminoacylation
ACIN_RS07740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACIN_RS07745	COG0750	zinc metalloprotease
ACIN_RS07750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACIN_RS07755	COG0575	Belongs to the CDS family
ACIN_RS07760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACIN_RS07775	COG0233	cytoplasmic translational termination
ACIN_RS07780	COG0528	UMP kinase activity
ACIN_RS07785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACIN_RS07790	COG0052	Belongs to the universal ribosomal protein uS2 family
ACIN_RS07805	COG0571	ribonuclease III activity
ACIN_RS07810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACIN_RS07820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACIN_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
ACIN_RS07830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACIN_RS07835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACIN_RS07840	COG0416	fatty acid biosynthetic process
ACIN_RS07845	COG2030	dehydratase
ACIN_RS07850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACIN_RS07860	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACIN_RS07865	COG1323	Belongs to the UPF0348 family
ACIN_RS07885	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACIN_RS07890	COG0742	ribosomal rna small subunit methyltransferase
ACIN_RS07910	COG0450	alkyl hydroperoxide reductase
ACIN_RS07930	COG1610	YqeY-like protein
ACIN_RS07940	COG0537	adenosine 5'-monophosphoramidase activity
ACIN_RS07945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACIN_RS07950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACIN_RS07955	COG2264	protein methyltransferase activity
ACIN_RS08005	COG2086	electron transfer activity
ACIN_RS08020	COG3326	Membrane
ACIN_RS08040	COG1253	flavin adenine dinucleotide binding
ACIN_RS08085	COG4120	Belongs to the binding-protein-dependent transport system permease family
ACIN_RS08100	COG0501	Belongs to the peptidase M48B family
ACIN_RS08115	COG0419	ATPase involved in DNA repair
ACIN_RS08130	COG2205	protein histidine kinase activity
ACIN_RS08135	COG0745	RESPONSE REGULATOR receiver
ACIN_RS08150	COG2239	Acts as a magnesium transporter
ACIN_RS08160	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACIN_RS08165	COG0534	Mate efflux family protein
ACIN_RS08180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACIN_RS08185	COG1464	Belongs to the NlpA lipoprotein family
ACIN_RS08190	COG0281	malic enzyme
ACIN_RS08200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACIN_RS08215	COG0824	Thioesterase
ACIN_RS08225	COG3859	Proton-coupled thiamine transporter YuaJ
ACIN_RS08230	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACIN_RS08235	COG2205	protein histidine kinase activity
ACIN_RS08235	COG2198	Histidine kinase
ACIN_RS08235	COG0784	Response regulator, receiver
ACIN_RS08240	COG3409	Peptidoglycan-binding domain 1 protein
ACIN_RS08240	COG0793	Belongs to the peptidase S41A family
ACIN_RS08250	COG2177	Part of the ABC transporter FtsEX involved in
ACIN_RS08255	COG2884	Cell division ATP-binding protein ftsE
ACIN_RS08270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACIN_RS08275	COG0653	protein targeting
ACIN_RS08280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACIN_RS08290	COG0765	amino acid transport
ACIN_RS08295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIN_RS08300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIN_RS08305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIN_RS08310	COG3437	response regulator, receiver
ACIN_RS08310	COG0784	Response regulator, receiver
ACIN_RS08320	COG0519	Catalyzes the synthesis of GMP from XMP
ACIN_RS08360	COG0583	DNA-binding transcription factor activity
ACIN_RS08375	COG0583	DNA-binding transcription factor activity
ACIN_RS08385	COG0300	oxidoreductase activity
ACIN_RS08390	COG1028	Short-chain dehydrogenase reductase Sdr
ACIN_RS08395	COG1073	alpha beta
ACIN_RS08400	COG2272	Belongs to the type-B carboxylesterase lipase family
ACIN_RS08405	COG1979	alcohol dehydrogenase
ACIN_RS08460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACIN_RS08465	COG1827	regulation of RNA biosynthetic process
ACIN_RS08500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIN_RS08510	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACIN_RS08520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACIN_RS08525	COG1560	Kdo2-lipid A biosynthetic process
ACIN_RS08555	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACIN_RS08575	COG1127	ABC transporter
ACIN_RS08580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACIN_RS08600	COG1077	Cell shape determining protein MreB Mrl
ACIN_RS08605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACIN_RS08630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACIN_RS08635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACIN_RS08640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACIN_RS08640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACIN_RS08645	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACIN_RS08650	COG0356	it plays a direct role in the translocation of protons across the membrane
ACIN_RS08660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACIN_RS08665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACIN_RS08685	COG0534	Mate efflux family protein
ACIN_RS08695	COG1597	lipid kinase activity
ACIN_RS08710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACIN_RS08715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACIN_RS08720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACIN_RS08735	COG0277	FAD linked oxidase domain protein
ACIN_RS08740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACIN_RS08745	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ACIN_RS08750	COG0590	tRNA wobble adenosine to inosine editing
ACIN_RS08925	COG0756	dUTP diphosphatase activity
ACIN_RS09005	COG0582	viral genome integration into host DNA
ACIN_RS09010	COG0583	DNA-binding transcription factor activity
ACIN_RS09015	COG2059	Chromate
ACIN_RS09040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACIN_RS09045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACIN_RS09050	COG1028	Short-chain dehydrogenase reductase Sdr
ACIN_RS09055	COG0456	acetyltransferase
ACIN_RS09055	COG1846	Transcriptional regulator
ACIN_RS09065	COG0456	acetyltransferase
ACIN_RS09160	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACIN_RS09285	COG0740	serine-type endopeptidase activity
ACIN_RS09305	COG1802	Transcriptional regulator
ACIN_RS09305	COG4626	Terminase
ACIN_RS09335	COG1475	DNA binding
ACIN_RS09435	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACIN_RS09470	COG5301	cellulose 1,4-beta-cellobiosidase activity
ACIN_RS09480	COG3299	homolog of phage Mu protein gp47
ACIN_RS09555	COG0740	serine-type endopeptidase activity
ACIN_RS09560	COG4695	Portal protein
ACIN_RS09665	COG3645	SOS response
ACIN_RS09665	COG3646	Phage regulatory protein
ACIN_RS09725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACIN_RS09730	COG1733	regulation of RNA biosynthetic process
ACIN_RS09735	COG2910	NAD(P)H-binding
ACIN_RS09770	COG1979	alcohol dehydrogenase
ACIN_RS09775	COG3829	transcription factor binding
ACIN_RS09785	COG2207	Transcriptional regulator
ACIN_RS09795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ACIN_RS09800	COG1882	Formate acetyltransferase
ACIN_RS09820	COG1115	amino acid carrier protein
ACIN_RS09830	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACIN_RS09830	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACIN_RS09830	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACIN_RS09830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACIN_RS09845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACIN_RS09845	COG0493	'glutamate synthase
ACIN_RS09860	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ACIN_RS09865	COG5002	protein histidine kinase activity
ACIN_RS09870	COG0745	RESPONSE REGULATOR receiver
ACIN_RS09875	COG0280	phosphate acetyltransferase
ACIN_RS09905	COG1301	dicarboxylic acid transport
ACIN_RS09910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ACIN_RS09915	COG0251	oxidation-reduction process
ACIN_RS09985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACIN_RS09990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACIN_RS09995	COG3858	chitin binding
ACIN_RS10000	COG1227	inorganic diphosphatase activity
ACIN_RS10005	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ACIN_RS10015	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ACIN_RS10020	COG1473	amidohydrolase
ACIN_RS10030	COG0165	Argininosuccinate lyase
ACIN_RS10040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACIN_RS10045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACIN_RS10050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACIN_RS10055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACIN_RS10055	COG4499	WXG100 protein secretion system (Wss), protein YukC
ACIN_RS10060	COG0166	Belongs to the GPI family
ACIN_RS10105	COG0741	lytic transglycosylase activity
ACIN_RS10110	COG0237	dephospho-CoA kinase activity
ACIN_RS10115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACIN_RS10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACIN_RS10140	COG1115	amino acid carrier protein
ACIN_RS10145	COG1757	Na H antiporter
ACIN_RS10150	COG0798	PFAM Bile acid sodium symporter
ACIN_RS10175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACIN_RS10180	COG2022	thiamine diphosphate biosynthetic process
ACIN_RS10190	COG0352	thiamine-phosphate diphosphorylase activity
ACIN_RS10200	COG0583	DNA-binding transcription factor activity
ACIN_RS10230	COG0583	DNA-binding transcription factor activity
ACIN_RS10235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ACIN_RS10240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ACIN_RS10240	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ACIN_RS10245	COG3964	amidohydrolase
ACIN_RS10270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACIN_RS10275	COG0490	domain, Protein
ACIN_RS10275	COG0471	metal ion transport
ACIN_RS10290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ACIN_RS10300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIN_RS10310	COG4771	TonB-dependent receptor
ACIN_RS10350	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ACIN_RS10355	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ACIN_RS10360	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ACIN_RS10370	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACIN_RS10375	COG0085	RNA polymerase activity
ACIN_RS10395	COG2801	Transposase and inactivated derivatives
ACIN_RS10410	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACIN_RS10415	COG0697	spore germination
ACIN_RS10425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACIN_RS10430	COG0154	amidase activity
ACIN_RS10435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACIN_RS10440	COG0626	cystathionine gamma-synthase activity
ACIN_RS10450	COG0751	glycine-tRNA ligase activity
ACIN_RS10455	COG0752	glycyl-tRNA synthetase alpha subunit
ACIN_RS10460	COG0531	amino acid
ACIN_RS10465	COG0463	Glycosyl transferase, family 2
ACIN_RS10480	COG1288	antiporter activity
ACIN_RS10485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACIN_RS10495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACIN_RS10500	COG0358	DNA primase activity
ACIN_RS10510	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ACIN_RS10515	COG0517	IMP dehydrogenase activity
ACIN_RS10520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACIN_RS10520	COG0574	Belongs to the PEP-utilizing enzyme family
ACIN_RS10535	COG3314	Sporulation integral membrane protein YlbJ
ACIN_RS10555	COG4139	cobalamin transport
ACIN_RS10565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACIN_RS10590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACIN_RS10605	COG1297	OPT oligopeptide transporter protein
ACIN_RS10610	COG0159	tryptophan synthase activity
ACIN_RS10615	COG0133	tryptophan synthase activity
ACIN_RS10620	COG0135	phosphoribosylanthranilate isomerase activity
ACIN_RS10660	COG2011	ABC-type metal ion transport system permease component
ACIN_RS10665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACIN_RS10685	COG2985	domain, Protein
ACIN_RS10685	COG0490	domain, Protein
ACIN_RS10695	COG1473	amidohydrolase
ACIN_RS10700	COG3681	Belongs to the UPF0597 family
ACIN_RS10710	COG0222	ribosome binding
ACIN_RS10715	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACIN_RS10720	COG0081	regulation of translation
ACIN_RS10725	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACIN_RS10730	COG0250	Participates in transcription elongation, termination and antitermination
ACIN_RS10740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACIN_RS10745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACIN_RS10795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACIN_RS10800	COG0426	domain, Protein
ACIN_RS10805	COG1115	amino acid carrier protein
ACIN_RS10810	COG4178	(ABC) transporter
ACIN_RS10820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACIN_RS10830	COG0277	FAD linked oxidase domain protein
ACIN_RS10835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACIN_RS10840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACIN_RS10850	COG0531	amino acid
ACIN_RS10855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACIN_RS10880	COG1335	isochorismatase
ACIN_RS10885	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACIN_RS10900	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACIN_RS10910	COG0248	Ppx GppA phosphatase
ACIN_RS10925	COG1346	cytolysis
ACIN_RS10935	COG1288	antiporter activity
ACIN_RS10940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACIN_RS10945	COG5599	Phosphatase
ACIN_RS10960	COG1959	2 iron, 2 sulfur cluster binding
ACIN_RS10970	COG0129	dihydroxy-acid dehydratase activity
ACIN_RS11020	COG1683	Conserved Protein
ACIN_RS11025	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ACIN_RS11025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ACIN_RS11030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ACIN_RS11035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ACIN_RS11050	COG0583	DNA-binding transcription factor activity
ACIN_RS11065	COG1473	amidohydrolase
ACIN_RS11070	COG1288	antiporter activity
ACIN_RS11080	COG0583	DNA-binding transcription factor activity
ACIN_RS11090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACIN_RS11100	COG1196	nuclear chromosome segregation
ACIN_RS11120	COG2176	DNA-directed DNA polymerase activity
ACIN_RS11135	COG2996	Protein conserved in bacteria
ACIN_RS11140	COG0799	negative regulation of ribosome biogenesis
ACIN_RS11145	COG1316	TRANSCRIPTIONal
ACIN_RS11150	COG1713	HD superfamily hydrolase involved in NAD metabolism
ACIN_RS11160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACIN_RS11165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ACIN_RS11170	COG0012	GTP binding
ACIN_RS11175	COG2239	Acts as a magnesium transporter
ACIN_RS11185	COG1263	PTS System
ACIN_RS11185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACIN_RS11190	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACIN_RS11195	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACIN_RS11210	COG0203	ribosomal protein L17
ACIN_RS11215	COG0202	RNA polymerase activity
ACIN_RS11220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACIN_RS11230	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACIN_RS11235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACIN_RS11245	COG0563	adenylate kinase activity
ACIN_RS11250	COG0201	protein transport
ACIN_RS11260	COG1841	ribosomal large subunit assembly
ACIN_RS11265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACIN_RS11270	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACIN_RS11275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACIN_RS11280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACIN_RS11285	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACIN_RS11290	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACIN_RS11295	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACIN_RS11305	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACIN_RS11310	COG0255	Belongs to the universal ribosomal protein uL29 family
ACIN_RS11315	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACIN_RS11320	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACIN_RS11325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACIN_RS11330	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACIN_RS11335	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACIN_RS11340	COG0089	rRNA binding
ACIN_RS11345	COG0088	Forms part of the polypeptide exit tunnel
ACIN_RS11350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACIN_RS11355	COG0051	transcription antitermination factor activity, RNA binding
ACIN_RS11360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACIN_RS11370	COG0049	tRNA binding
ACIN_RS11375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACIN_RS11380	COG1358	cellular component organization or biogenesis
ACIN_RS11405	COG0488	(ABC) transporter
ACIN_RS11410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACIN_RS11435	COG0542	response to heat
ACIN_RS11465	COG1979	alcohol dehydrogenase
ACIN_RS11470	COG2801	Transposase and inactivated derivatives
ACIN_RS11480	COG1012	belongs to the aldehyde dehydrogenase family
ACIN_RS11485	COG0640	Transcriptional regulator
ACIN_RS11495	COG1114	Component of the transport system for branched-chain amino acids
ACIN_RS11500	COG1028	Short-chain dehydrogenase reductase Sdr
ACIN_RS11505	COG1278	Cold shock
ACIN_RS11510	COG2827	Endonuclease containing a URI domain
ACIN_RS11515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACIN_RS11525	COG0492	ferredoxin-NADP+ reductase activity
ACIN_RS11530	COG1196	nuclear chromosome segregation
ACIN_RS11530	COG0741	lytic transglycosylase activity
ACIN_RS11530	COG0739	heme binding
ACIN_RS11535	COG0583	DNA-binding transcription factor activity
ACIN_RS11560	COG2244	polysaccharide biosynthetic process
ACIN_RS11565	COG1924	4 iron, 4 sulfur cluster binding
ACIN_RS11570	COG0071	Belongs to the small heat shock protein (HSP20) family
ACIN_RS11585	COG2801	Transposase and inactivated derivatives
ACIN_RS11595	COG2873	o-acetylhomoserine
ACIN_RS11605	COG0519	Catalyzes the synthesis of GMP from XMP
ACIN_RS11615	COG2801	Transposase and inactivated derivatives
ACIN_RS11630	COG1115	amino acid carrier protein
ACIN_RS11640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACIN_RS11660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACIN_RS11675	COG0534	Mate efflux family protein
ACIN_RS11685	COG0114	fumarate hydratase activity
ACIN_RS11695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACIN_RS11700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACIN_RS11705	COG0066	3-isopropylmalate dehydratase activity
ACIN_RS11725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACIN_RS11730	COG0305	Participates in initiation and elongation during chromosome replication
ACIN_RS11735	COG0359	binds to the 23S rRNA
ACIN_RS11740	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ACIN_RS11755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACIN_RS11760	COG0039	L-malate dehydrogenase activity
ACIN_RS11765	COG2610	gluconate transmembrane transporter activity
ACIN_RS11775	COG1473	amidohydrolase
ACIN_RS11780	COG1160	GTP binding
ACIN_RS11785	COG1160	GTP binding
ACIN_RS11795	COG0252	asparaginase activity
ACIN_RS11800	COG0156	8-amino-7-oxononanoate synthase activity
ACIN_RS11825	COG0745	RESPONSE REGULATOR receiver
ACIN_RS11835	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACIN_RS11840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACIN_RS11845	COG0497	DNA recombination
ACIN_RS11865	COG1475	DNA binding
ACIN_RS11870	COG1192	Involved in chromosome partitioning
ACIN_RS11875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACIN_RS11880	COG1464	Belongs to the NlpA lipoprotein family
ACIN_RS11905	COG0357	Ribosomal RNA small subunit methyltransferase G
ACIN_RS11910	COG0445	tRNA wobble uridine modification
ACIN_RS11915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACIN_RS11920	COG1847	R3H domain protein
ACIN_RS11925	COG0706	membrane insertase activity
ACIN_RS11930	COG0594	ribonuclease P activity
ACIN_RS11935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACIN_RS11940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACIN_RS11950	COG2194	sulfuric ester hydrolase activity
ACIN_RS11960	COG1115	amino acid carrier protein
ACIN_RS11965	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACIN_RS11980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACIN_RS11985	COG4946	Tricorn protease homolog
ACIN_RS11985	COG1506	peptidase
ACIN_RS11985	COG0823	Involved in the tonB-independent uptake of proteins
ACIN_RS12055	COG1196	nuclear chromosome segregation