locus-tag	class	description
DFR85_RS01175	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DFR85_RS02215	ENOG4108RAC	Rubrerythrin
DFR85_RS04025	ENOG4105D1F	ATP-binding protein
DFR85_RS04635	ENOG4105DIK	(ABC) transporter
DFR85_RS06485	ENOG4105EQR	Transposase IS116 IS110 IS902
DFR85_RS08260	ENOG4107QNK	)-transporter
DFR85_RS11240	ENOG4108K28	Arsenite oxidase, large subunit
DFR85_RS13760	ENOG4107TSN	permease
DFR85_RS13770	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DFR85_RS14285	ENOG4108IUW	ABC transporter
DFR85_RS14560	ENOG41067TZ	transcriptional regulator, MarR family
DFR85_RS14960	ENOG4105CPQ	Dehydrogenase
DFR85_RS16190	ENOG4105CSH	Transporter
DFR85_RS16250	ENOG4105DA5	(ABC) transporter
DFR85_RS16285	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
DFR85_RS16320	ENOG4105EYF	MMPL domain protein
DFR85_RS16330	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
DFR85_RS16365	ENOG4105CTD	carboxy-peptidase
DFR85_RS16370	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
DFR85_RS16375	ENOG4105VUC	UPF0237 protein
DFR85_RS16440	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DFR85_RS16460	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DFR85_RS16480	ENOG4105JEU	Glycosyl transferase, family 2
DFR85_RS16485	ENOG4105F0N	pyrophosphate phospho-hydrolase
DFR85_RS16490	ENOG4105DK2	UPF0207 protein
DFR85_RS16495	ENOG4105DWF	phosphomethylpyrimidine kinase
DFR85_RS16525	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
DFR85_RS16535	ENOG4105CJ1	ABC, transporter
DFR85_RS16585	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
DFR85_RS16600	ENOG4105C3M	thioredoxin reductase
DFR85_RS16605	ENOG4105ECY	inositol monophosphatase
DFR85_RS16610	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR85_RS16650	ENOG4105EM7	Selenocysteine-specific translation elongation factor
DFR85_RS16685	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DFR85_RS16725	ENOG4105CPQ	Dehydrogenase
DFR85_RS16730	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
DFR85_RS16740	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DFR85_RS16745	ENOG4108RVA	ribokinase
DFR85_RS16760	ENOG4108IYU	L-aspartate oxidase
DFR85_RS16775	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
DFR85_RS16845	ENOG4107QJZ	Glycosyl transferase, family 2
DFR85_RS16860	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
DFR85_RS16880	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
DFR85_RS16910	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
DFR85_RS16930	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
DFR85_RS16940	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DFR85_RS16965	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DFR85_RS16970	ENOG4107QPD	alcohol dehydrogenase
DFR85_RS17015	ENOG4105CPQ	Dehydrogenase
DFR85_RS17030	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
DFR85_RS17035	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DFR85_RS17040	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
DFR85_RS17100	ENOG4105G5W	regulator Fur family
DFR85_RS17120	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DFR85_RS17145	ENOG4105K63	Thioredoxin
DFR85_RS17155	ENOG4105CEP	NADH dehydrogenase
DFR85_RS17215	ENOG4105CAY	ferredoxin--nadp reductase
DFR85_RS17230	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DFR85_RS17245	ENOG4107EPV	Aminotransferase class V
DFR85_RS17250	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
DFR85_RS17260	ENOG4108K7V	UPF0284 protein
DFR85_RS17280	ENOG4105J7I	hydrolase
DFR85_RS17295	ENOG4107YU2	histidine triad (hIT) protein
DFR85_RS17300	ENOG4105D3W	isochorismatase
DFR85_RS17315	ENOG4107VIJ	nudix hydrolase
DFR85_RS17330	ENOG4105E50	uracil-dna glycosylase
DFR85_RS17340	ENOG4105C4K	Nad synthetase
DFR85_RS17345	ENOG4105C4K	Nad synthetase
DFR85_RS17370	ENOG4105C01	Dihydroxy-acid dehydratase
DFR85_RS17375	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
DFR85_RS17395	ENOG4108HMX	isocitrate dehydrogenase (NADP)
DFR85_RS17410	ENOG4105KZX	Pterin carbinolamine dehydratase
DFR85_RS17435	ENOG4107QX8	SPFH domain, Band 7 family protein
DFR85_RS17440	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
DFR85_RS17490	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DFR85_RS17525	ENOG4105ETU	transcriptional activator (TenA
DFR85_RS17530	ENOG4105CHR	reductase
DFR85_RS17535	ENOG4105C7Z	Conserved Protein
DFR85_RS17580	ENOG41088YS	Glycosyl transferase (Group 1
DFR85_RS17605	ENOG4107RQ2	Cytochrome c oxidase, subunit I
DFR85_RS17625	ENOG4105CJ1	ABC, transporter
DFR85_RS17670	ENOG4107QJE	Chromosome Partitioning Protein
DFR85_RS17710	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
DFR85_RS17745	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
DFR85_RS17755	ENOG4107QRT	dEAD DEAH box helicase
DFR85_RS17765	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
DFR85_RS17775	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DFR85_RS17810	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
DFR85_RS17820	ENOG4105C54	Major Facilitator superfamily
DFR85_RS17835	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
DFR85_RS17840	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DFR85_RS17850	ENOG4108JPZ	Monovalent cation H antiporter subunit D
DFR85_RS17855	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR85_RS17860	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR85_RS17865	ENOG4108JPZ	Monovalent cation H antiporter subunit D
DFR85_RS17870	ENOG4107TDF	Formate hydrogenlyase subunit 4
DFR85_RS17915	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DFR85_RS17920	ENOG4107QN2	dihydrolipoyl dehydrogenase
DFR85_RS17935	ENOG4105CSH	Transporter
DFR85_RS17955	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR85_RS17960	ENOG4105C26	Dehydrogenase
DFR85_RS17965	ENOG4107QY8	reductase
DFR85_RS17975	ENOG4105DQU	oxidoreductase, subunit beta
DFR85_RS17980	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
DFR85_RS18005	ENOG4105CKK	Glycosyl transferase, family 2
DFR85_RS18010	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
DFR85_RS18050	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DFR85_RS18090	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DFR85_RS18130	ENOG4105CYW	agmatinase
DFR85_RS18155	ENOG4105CH2	amidohydrolase
DFR85_RS18170	ENOG4105CUB	amino acid
DFR85_RS18230	ENOG4105CUB	amino acid
DFR85_RS18235	ENOG4105DDK	oxidoreductase, beta subunit
DFR85_RS18240	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
DFR85_RS18255	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DFR85_RS18265	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DFR85_RS18270	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DFR85_RS18315	ENOG4105CQM	Urea amidohydrolase subunit alpha
DFR85_RS18320	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
DFR85_RS18325	ENOG4108S0R	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
DFR85_RS18330	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
DFR85_RS18340	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DFR85_RS18370	ENOG4105CJ1	ABC, transporter
DFR85_RS18375	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
DFR85_RS18380	ENOG4108IUX	(ABC) transporter
DFR85_RS18440	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DFR85_RS18445	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DFR85_RS18450	ENOG4105C3U	ABC transporter
DFR85_RS18455	ENOG4108JQ7	(ABC) transporter
DFR85_RS18515	ENOG4105D5Q	Arginine ornithine antiporter
DFR85_RS18540	ENOG4108M14	stage v sporulation protein t
DFR85_RS18550	ENOG4105DG4	malate L-lactate dehydrogenase
DFR85_RS18590	ENOG4105DZC	cytosine deaminase
DFR85_RS18605	ENOG4105D49	3-dehydroquinate synthase
DFR85_RS18615	ENOG4105C5F	glutamine synthetase
DFR85_RS18625	ENOG4105FUY	alpha subunit
DFR85_RS18635	ENOG4105CSH	Transporter
DFR85_RS18660	ENOG4105C4K	Nad synthetase
DFR85_RS18665	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
DFR85_RS18675	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
DFR85_RS18705	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
DFR85_RS18720	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DFR85_RS18790	ENOG4105CI2	imidazolone-5-propionate hydrolase
DFR85_RS18795	ENOG4105D2S	major facilitator superfamily
DFR85_RS18830	ENOG4107QTZ	amino acid
DFR85_RS18835	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DFR85_RS18850	ENOG4108I5U	Uridine phosphorylase
DFR85_RS18875	ENOG41082XB	radical SAM domain protein
DFR85_RS18925	ENOG4105EUB	pirin domain protein
DFR85_RS18945	ENOG4105CD8	aminopeptidase N
DFR85_RS18960	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DFR85_RS18975	ENOG4105D0M	Protease HtpX homolog
DFR85_RS18990	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
DFR85_RS19025	ENOG4105EQR	Transposase IS116 IS110 IS902
DFR85_RS19170	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
DFR85_RS19180	ENOG4105EYF	MMPL domain protein
DFR85_RS19260	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DFR85_RS19265	ENOG4105DB1	molybdopterin oxidoreductase
DFR85_RS19310	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
DFR85_RS19320	ENOG4108U1V	ABC transporter, permease
DFR85_RS19325	ENOG4105E0A	ABC, transporter
DFR85_RS19380	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DFR85_RS19390	ENOG4105E33	succinate dehydrogenase
DFR85_RS19415	ENOG4105DPX	Hydrogenase, large subunit
DFR85_RS19450	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DFR85_RS19515	ENOG4105DIW	FeS assembly protein SUFB
DFR85_RS19525	ENOG4108R96	Methyltransferase, YaeB family
DFR85_RS19610	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
DFR85_RS19635	ENOG4105DPX	Hydrogenase, large subunit
DFR85_RS19650	ENOG4105CQS	hydrogenase expression formation protein HypD
DFR85_RS19750	ENOG4108M15	ABC transporter
DFR85_RS19780	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
DFR85_RS19835	ENOG4105E4P	ATPase (AAA
DFR85_RS19840	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DFR85_RS19850	ENOG4105CK5	oxidoreductase
DFR85_RS19910	ENOG4108FN7	Aldo keto reductase
DFR85_RS19945	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DFR85_RS19995	ENOG4105C3U	ABC transporter
DFR85_RS20000	ENOG4108JQ7	(ABC) transporter
DFR85_RS20015	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DFR85_RS20050	ENOG4105CE4	GlcNAc 6-P deacetylase
DFR85_RS20055	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DFR85_RS20115	ENOG4108SHN	Glycosyl transferase, family 2
DFR85_RS20125	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
DFR85_RS20130	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
DFR85_RS20135	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
DFR85_RS20140	ENOG4108SHN	Glycosyl transferase, family 2
DFR85_RS20150	ENOG4105CG5	Glycosyl transferase (Group 1
DFR85_RS20160	ENOG4107T8Q	Glycosyl transferase (Group 1
DFR85_RS20245	ENOG4108SHN	Glycosyl transferase, family 2
DFR85_RS20260	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DFR85_RS20320	ENOG4107QTZ	amino acid
DFR85_RS20375	ENOG4105D9P	serine threonine protein kinase
DFR85_RS20450	ENOG4105D9P	serine threonine protein kinase
DFR85_RS20665	ENOG4105E4P	ATPase (AAA
DFR85_RS20710	ENOG4108SMP	Nad-dependent epimerase dehydratase
DFR85_RS20820	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DFR85_RS20860	ENOG4107QRS	glycosyltransferase group 2 family protein
DFR85_RS21010	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DFR85_RS21025	ENOG4108PQP	glycosyl transferase group 1
DFR85_RS21045	ENOG4105C59	p-type ATPase
DFR85_RS21095	ENOG4105C54	Major Facilitator superfamily
DFR85_RS21100	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
DFR85_RS21145	ENOG4105CD5	CoA-binding domain protein
DFR85_RS21150	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
DFR85_RS21180	ENOG4107R56	PP-loop domain protein
DFR85_RS21200	ENOG4105C1J	atp-dependent rna helicase
DFR85_RS21265	ENOG4107RE3	peptidase, S41
DFR85_RS21295	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
DFR85_RS21300	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DFR85_RS21345	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DFR85_RS21375	ENOG41079KZ	Major Facilitator Superfamily
DFR85_RS21395	ENOG4105EGS	Mechanosensitive ion channel
DFR85_RS21415	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
DFR85_RS21445	ENOG4105ETU	transcriptional activator (TenA
DFR85_RS21455	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
DFR85_RS21460	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DFR85_RS21500	ENOG4105CGK	Exodeoxyribonuclease III
DFR85_RS21520	ENOG4107SVH	Potassium channel protein
DFR85_RS21530	ENOG4105BZP	glycoside hydrolase 15-related
DFR85_RS21585	ENOG4107RQ2	Cytochrome c oxidase, subunit I
DFR85_RS21590	ENOG4105C54	Major Facilitator superfamily
DFR85_RS21610	ENOG4105FDK	ABC transporter
DFR85_RS21615	ENOG4105DQ5	transport system permease protein
DFR85_RS21645	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DFR85_RS21650	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DFR85_RS21655	ENOG4105EHU	Circadian clock protein KaiC
DFR85_RS21665	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
DFR85_RS21680	ENOG4105D3R	alkyl hydroperoxide reductase
DFR85_RS21695	ENOG4105BZN	citrate synthase
DFR85_RS21720	ENOG4105CQR	helicase
DFR85_RS21740	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DFR85_RS21760	ENOG4105C1J	atp-dependent rna helicase
DFR85_RS21775	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
DFR85_RS21785	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DFR85_RS21790	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DFR85_RS21815	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
DFR85_RS21850	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
DFR85_RS21855	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
DFR85_RS21875	ENOG4108VVK	transcriptional Regulator, AsnC
DFR85_RS21890	ENOG4105D44	asparaginase
DFR85_RS21905	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
DFR85_RS21925	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
DFR85_RS21950	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
DFR85_RS21965	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DFR85_RS21975	ENOG4105C28	cystathionine
DFR85_RS22040	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
DFR85_RS22075	ENOG4106HK8	GPR1 FUN34 yaaH family protein
DFR85_RS22080	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR85_RS22110	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
DFR85_RS22120	ENOG4105CNH	Multidrug resistance protein MdtL
DFR85_RS22125	ENOG4107YZX	Universal stress protein
DFR85_RS22130	ENOG4105CJ1	ABC, transporter
DFR85_RS22165	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
DFR85_RS22175	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
DFR85_RS22190	ENOG4105CND	Glycosyl transferase, family 2
DFR85_RS22200	ENOG4105DWF	phosphomethylpyrimidine kinase
DFR85_RS22205	ENOG4108RVA	ribokinase
DFR85_RS22210	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
DFR85_RS22250	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
DFR85_RS22270	ENOG4105CPQ	Dehydrogenase
DFR85_RS22275	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
DFR85_RS22285	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DFR85_RS22290	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DFR85_RS22295	ENOG4105D0M	Protease HtpX homolog
DFR85_RS22300	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DFR85_RS22325	ENOG41061GT	Aldolase
DFR85_RS22345	ENOG4105EN6	Membrane
DFR85_RS22360	ENOG4108JJB	ABC transporter
DFR85_RS22380	ENOG4105CMR	udp-glucose 4-epimerase
DFR85_RS22400	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DFR85_RS22405	ENOG4108KB0	deacetylase
DFR85_RS22410	ENOG4105C8Y	Acetylornithine aminotransferase
DFR85_RS22415	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DFR85_RS22430	ENOG4105CAS	nag kinase
DFR85_RS22435	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DFR85_RS22460	ENOG41080HJ	6-phospho 3-hexuloisomerase
DFR85_RS22525	ENOG4105C5S	asparaginyl-tRNA synthetase
DFR85_RS22530	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
DFR85_RS22550	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR85_RS22560	ENOG4105C2M	dna polymerase I
DFR85_RS22565	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DFR85_RS22570	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
DFR85_RS22575	ENOG4105D52	delta-aminolevulinic acid dehydratase
DFR85_RS22580	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DFR85_RS22585	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
DFR85_RS22610	ENOG41080HI	glycine oxidase
DFR85_RS22620	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
DFR85_RS22625	ENOG4105DHP	deoxycytidine triphosphate deaminase
DFR85_RS22670	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
DFR85_RS22685	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DFR85_RS22710	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DFR85_RS22720	ENOG4105C3M	thioredoxin reductase
DFR85_RS22735	ENOG4105CHR	reductase
DFR85_RS22770	ENOG4108Z1Z	gCN5-related N-acetyltransferase
DFR85_RS22775	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DFR85_RS22830	ENOG4107RB4	Cytidine monophosphate kinase
DFR85_RS22850	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DFR85_RS22860	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DFR85_RS22885	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DFR85_RS22895	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DFR85_RS22910	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
DFR85_RS22925	ENOG41082SA	50s ribosomal protein l29
DFR85_RS22930	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
DFR85_RS22935	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DFR85_RS22940	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DFR85_RS22945	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DFR85_RS22950	ENOG41082UH	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DFR85_RS22955	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DFR85_RS22960	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DFR85_RS22970	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DFR85_RS22975	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DFR85_RS22995	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DFR85_RS23000	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DFR85_RS23030	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
DFR85_RS23035	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DFR85_RS23070	ENOG4105C3G	gtp-binding protein
DFR85_RS23075	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DFR85_RS23085	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
DFR85_RS23090	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DFR85_RS23095	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
DFR85_RS23135	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
DFR85_RS23160	ENOG4105CY0	Metallo-Beta-Lactamase
DFR85_RS23165	ENOG4108MDK	Dehydrogenase
DFR85_RS23170	ENOG4108YZY	peptidylprolyl cis-trans isomerase
DFR85_RS23180	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
DFR85_RS23185	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DFR85_RS23215	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DFR85_RS23225	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR85_RS23240	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
DFR85_RS23260	ENOG4105CUT	histidyl-tRNA synthetase
DFR85_RS23275	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DFR85_RS23300	ENOG4107NFR	Fructose-1,6-bisphosphatase
DFR85_RS23360	ENOG4108FPN	Integrase
DFR85_RS23390	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
DFR85_RS23440	ENOG4108S4H	thioesterase Superfamily protein
DFR85_RS23460	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DFR85_RS23480	ENOG4105C7B	Threonine dehydratase
DFR85_RS23485	ENOG4105CQC	Prephenate dehydratase
DFR85_RS23495	ENOG4105DZ0	fad dependent oxidoreductase
DFR85_RS23515	ENOG4105C83	adenylosuccinate lyase
DFR85_RS23530	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DFR85_RS23535	ENOG4105WCJ	ec 1.1.1.193
DFR85_RS23545	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
DFR85_RS23550	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DFR85_RS23555	ENOG4105KG3	cytidine deaminase
DFR85_RS23560	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
DFR85_RS23580	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DFR85_RS23585	ENOG4105C6K	Malic enzyme
DFR85_RS23595	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DFR85_RS23600	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DFR85_RS23605	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DFR85_RS23610	ENOG4105XPM	ribosomal protein
DFR85_RS23630	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DFR85_RS23635	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DFR85_RS23640	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DFR85_RS23675	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
DFR85_RS23680	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DFR85_RS23695	ENOG4107QRT	dEAD DEAH box helicase
DFR85_RS23725	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
DFR85_RS23750	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DFR85_RS23760	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
DFR85_RS23765	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
DFR85_RS23780	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
DFR85_RS23790	ENOG4105EM7	Selenocysteine-specific translation elongation factor
DFR85_RS23800	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
DFR85_RS23815	ENOG4105E3H	phosphoglycerate mutase
DFR85_RS23820	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR85_RS23825	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
DFR85_RS23870	ENOG4105CPC	Aldo Keto reductase
DFR85_RS23875	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DFR85_RS23885	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DFR85_RS23900	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
DFR85_RS23910	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
DFR85_RS23940	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
DFR85_RS23955	ENOG4108ZJT	translation initiation factor, Sui1
DFR85_RS23975	ENOG4105EM7	Selenocysteine-specific translation elongation factor
DFR85_RS24000	ENOG4105EYF	MMPL domain protein
DFR85_RS24035	ENOG4105D1F	ATP-binding protein
DFR85_RS24080	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DFR85_RS24145	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DFR85_RS24205	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DFR85_RS24210	ENOG4105D1H	recombination factor protein RarA
DFR85_RS24220	ENOG4108V1U	phospholipid-binding protein
DFR85_RS24225	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
DFR85_RS24255	ENOG4105DJT	lAO AO transport system ATPase
DFR85_RS24280	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DFR85_RS24285	ENOG4107RWR	Sodium hydrogen exchanger
DFR85_RS24315	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
DFR85_RS24320	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
DFR85_RS24335	ENOG4105D82	Glutamate dehydrogenase
DFR85_RS24355	ENOG41086CI	Bifunctional phosphoglucose phosphomannose isomerase
DFR85_RS24365	ENOG4107SJS	nitrite reductase, (NAD(P)H)
DFR85_RS24385	ENOG4108S4H	thioesterase Superfamily protein
DFR85_RS24400	ENOG4105C1G	acyl-Coa dehydrogenase
DFR85_RS24405	ENOG4105EET	magnesium chelatase
DFR85_RS24410	ENOG4105CTK	cobaltochelatase, cobn subunit
DFR85_RS24425	ENOG4105E4R	Precorrin-3B C17-methyltransferase
DFR85_RS24440	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DFR85_RS24445	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
DFR85_RS24460	ENOG41081F0	Precorrin-8x methylmutase
DFR85_RS24465	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DFR85_RS24475	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DFR85_RS24490	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
DFR85_RS24500	ENOG4105CSM	endonuclease III
DFR85_RS24515	ENOG4107QRT	dEAD DEAH box helicase
DFR85_RS24545	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DFR85_RS24550	ENOG4105CEV	competence damage-inducible protein
DFR85_RS24555	ENOG4105F2Z	3-oxoadipate enol-lactonase
DFR85_RS24570	ENOG4105E8R	UPF0173 metal-dependent hydrolase
DFR85_RS24575	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
DFR85_RS24595	ENOG4105DCI	Phosphohydrolase
DFR85_RS24610	ENOG4105XPM	ribosomal protein
DFR85_RS24660	ENOG4105CRK	lysyL-tRNA synthetase
DFR85_RS24695	ENOG4105CQ2	DNA polymerase
DFR85_RS24705	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DFR85_RS24715	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
DFR85_RS24725	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DFR85_RS24730	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DFR85_RS24735	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
DFR85_RS24745	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DFR85_RS24750	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DFR85_RS24755	ENOG4108UJD	30S ribosomal protein S9
DFR85_RS24765	ENOG4105CE9	30S ribosomal protein S2
DFR85_RS24770	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
DFR85_RS24785	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
DFR85_RS24790	ENOG4105EAH	synthase
DFR85_RS24795	ENOG4105ESV	Glycosyl transferase, family 4
DFR85_RS24835	ENOG4105F8V	Hydrolase, tatD family
DFR85_RS24880	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
DFR85_RS24900	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DFR85_RS24910	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DFR85_RS24935	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
DFR85_RS24950	ENOG4105D1Z	hydroxypyruvate reductase
DFR85_RS24955	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR85_RS24960	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DFR85_RS24965	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
DFR85_RS24975	ENOG4107YZX	Universal stress protein
DFR85_RS24990	ENOG4105MRR	Transcriptional regulator (By similarity)
DFR85_RS25000	ENOG4105D6E	homoserine dehydrogenase
DFR85_RS25005	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
DFR85_RS25015	ENOG4105E39	Enoyl-CoA hydratase
DFR85_RS25055	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
DFR85_RS25065	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DFR85_RS25080	ENOG4105CH7	arginosuccinase
DFR85_RS25085	ENOG4105CDH	Citrulline--aspartate ligase
DFR85_RS25100	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
DFR85_RS25105	ENOG4105C12	Phosphoribosylglycinamide synthetase
DFR85_RS25120	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
DFR85_RS25125	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
DFR85_RS25145	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DFR85_RS25150	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
DFR85_RS25180	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
DFR85_RS25200	ENOG4105CXT	aspartate transcarbamylase
DFR85_RS25205	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
DFR85_RS25215	ENOG4105CD3	dihydroorotase
DFR85_RS25220	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
DFR85_RS25235	ENOG41081FY	multiple antibiotic resistance (MarC)-related
DFR85_RS25240	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
DFR85_RS25255	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DFR85_RS25260	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
DFR85_RS25270	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
DFR85_RS25275	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
DFR85_RS25280	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DFR85_RS25285	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
DFR85_RS25295	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
DFR85_RS25300	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
DFR85_RS25305	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DFR85_RS25315	ENOG4105C8T	Leucyl-tRNA synthetase
DFR85_RS25325	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
DFR85_RS25345	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
DFR85_RS25360	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
DFR85_RS25370	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
DFR85_RS25375	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DFR85_RS25390	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DFR85_RS25410	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
DFR85_RS25420	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DFR85_RS25435	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
DFR85_RS25440	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
DFR85_RS25465	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DFR85_RS25485	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DFR85_RS25495	ENOG4105CQ2	DNA polymerase
DFR85_RS25510	ENOG4105CZA	synthase
DFR85_RS25515	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR85_RS25520	ENOG4105D65	subunit l
DFR85_RS25525	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR85_RS25535	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR85_RS25545	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR85_RS25550	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DFR85_RS25560	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
DFR85_RS25585	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DFR85_RS25630	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
DFR85_RS25635	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DFR85_RS25640	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DFR85_RS25645	ENOG4105E2X	shikimate dehydrogenase
DFR85_RS25650	ENOG4105D49	3-dehydroquinate synthase
DFR85_RS25655	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
DFR85_RS25665	ENOG4108IUS	Transketolase
DFR85_RS25670	ENOG4108HHA	Transketolase
DFR85_RS25675	ENOG4105D06	uba thif-type nad fad binding protein
DFR85_RS25705	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DFR85_RS25730	ENOG4105EYU	Glutamine amido-transferase
DFR85_RS25735	ENOG4105CBC	glutamate synthase
DFR85_RS25780	ENOG4105C22	threonyL-tRNA synthetase
DFR85_RS25790	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DFR85_RS25840	ENOG4105CIF	Ornithine Cyclodeaminase
DFR85_RS25855	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DFR85_RS25865	ENOG4108Z0R	Transferase
DFR85_RS25870	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DFR85_RS25880	ENOG4105CEY	Amp-dependent synthetase and ligase
DFR85_RS25885	ENOG4105K63	Thioredoxin
DFR85_RS25890	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
DFR85_RS25895	ENOG4105C5F	glutamine synthetase
DFR85_RS25905	ENOG4105EUJ	GTP cyclohydrolase i
DFR85_RS25915	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DFR85_RS25930	ENOG4105C6T	cysteine synthase
DFR85_RS25995	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DFR85_RS26010	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DFR85_RS26020	ENOG4108VZM	50s ribosomal protein L10
DFR85_RS26030	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DFR85_RS26045	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
DFR85_RS26050	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DFR85_RS26075	ENOG4107YZX	Universal stress protein
DFR85_RS26085	ENOG4105BZA	Phosphoglycerate kinase
DFR85_RS26230	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
DFR85_RS26260	ENOG4105C3K	feS assembly ATPase SufC
DFR85_RS26280	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DFR85_RS26285	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
DFR85_RS26290	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DFR85_RS26295	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DFR85_RS26310	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DFR85_RS26330	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR85_RS26335	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DFR85_RS26350	ENOG4108JQ1	Dehydrogenase
DFR85_RS26355	ENOG4105GRF	N-glycosylase DNA lyase
DFR85_RS26390	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DFR85_RS26400	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DFR85_RS26405	ENOG4105DDQ	anthranilate synthase
DFR85_RS26410	ENOG4105CRQ	synthase (Component I)
DFR85_RS26415	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
DFR85_RS26425	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DFR85_RS26430	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DFR85_RS26435	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
DFR85_RS26440	ENOG4105CZA	synthase
DFR85_RS26450	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
DFR85_RS26475	ENOG4105CFH	Aspartokinase
DFR85_RS26480	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
DFR85_RS26495	ENOG4105DBV	ornithine carbamoyltransferase
DFR85_RS26530	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DFR85_RS26555	ENOG4105C75	arginyL-tRNA synthetase
DFR85_RS26580	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DFR85_RS26585	ENOG4105HDK	L-asparaginase
DFR85_RS26615	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
DFR85_RS26665	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
DFR85_RS26680	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DFR85_RS26685	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DFR85_RS26690	ENOG4105VF7	tolerance protein
DFR85_RS26700	ENOG4105CB5	ATP-dependent DNA helicase recG
DFR85_RS26725	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
DFR85_RS26755	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DFR85_RS26770	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DFR85_RS26785	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DFR85_RS26790	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
DFR85_RS26805	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DFR85_RS26815	ENOG4107SDT	Homocitrate synthase
DFR85_RS26920	ENOG4105C54	Major Facilitator superfamily
DFR85_RS26935	ENOG4107YZX	Universal stress protein
DFR85_RS26945	ENOG4105BZP	glycoside hydrolase 15-related
DFR85_RS26950	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DFR85_RS26985	ENOG4105BZU	Histidine kinase
DFR85_RS27005	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DFR85_RS27040	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DFR85_RS27050	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
DFR85_RS27065	ENOG4105M7V	2'-5' rna ligase
DFR85_RS27095	ENOG41066FR	extracellular solute-binding protein
DFR85_RS27100	ENOG4108IXY	short-chain dehydrogenase reductase
DFR85_RS27120	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
DFR85_RS27125	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DFR85_RS27130	ENOG4105C22	threonyL-tRNA synthetase
DFR85_RS27145	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
DFR85_RS27150	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
DFR85_RS27160	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DFR85_RS27165	ENOG4105DCI	Phosphohydrolase
DFR85_RS27195	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
DFR85_RS27225	ENOG4105DGU	Histone deacetylase
DFR85_RS27250	ENOG4107QN2	dihydrolipoyl dehydrogenase
DFR85_RS27260	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
DFR85_RS27265	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
DFR85_RS27280	ENOG4107QN2	dihydrolipoyl dehydrogenase
DFR85_RS27295	ENOG41086B8	CoB-CoM heterodisulfide reductase
DFR85_RS27300	ENOG4105VG5	Membrane
DFR85_RS27305	ENOG4105FEU	K -dependent Na -Ca exchanger
DFR85_RS27320	ENOG4105CQB	FAD linked oxidase domain protein
DFR85_RS27420	ENOG4105D3W	isochorismatase
DFR85_RS27465	ENOG4107RGD	Major Facilitator superfamily
DFR85_RS27490	ENOG4105CPQ	Dehydrogenase
DFR85_RS27510	ENOG4105KME	endoribonuclease L-psp
DFR85_RS27555	ENOG4105CP7	Triose-phosphate isomerase
DFR85_RS27570	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
DFR85_RS27575	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
DFR85_RS27580	ENOG4105D4A	Cell wall formation (By similarity)
DFR85_RS27595	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR85_RS27610	ENOG4107QTZ	amino acid
DFR85_RS27615	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DFR85_RS27630	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DFR85_RS27660	ENOG4108UR0	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DFR85_RS27665	ENOG4105DF9	Lipoate-protein, ligase
DFR85_RS27690	ENOG4105T58	Dithiol-disulfide isomerase
DFR85_RS27760	ENOG4107QM5	aconitate hydratase
DFR85_RS27775	ENOG4108M15	ABC transporter
DFR85_RS27800	ENOG4105D0M	Protease HtpX homolog
DFR85_RS27840	ENOG4108R96	Methyltransferase, YaeB family
DFR85_RS27860	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR85_RS27875	ENOG4107QR9	Iron-sulfur cluster binding protein
DFR85_RS27885	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
DFR85_RS27890	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
DFR85_RS27895	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
DFR85_RS27900	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
DFR85_RS27915	ENOG4108FN7	Aldo keto reductase
DFR85_RS27985	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
DFR85_RS28085	ENOG4105VG1	fes assembly suf system protein
DFR85_RS28115	ENOG4105C0D	helicase
DFR85_RS28140	ENOG4105C5X	domain protein
DFR85_RS28145	ENOG4105C4X	radical SAM domain protein
DFR85_RS28160	ENOG4105D1H	recombination factor protein RarA
DFR85_RS28170	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DFR85_RS28325	ENOG4107S4Y	M20 DapE family protein YgeY
DFR85_RS28335	ENOG4105C5F	glutamine synthetase
DFR85_RS28345	ENOG4105BZ1	(ABC) transporter
DFR85_RS28375	ENOG4105DQU	oxidoreductase, subunit beta
DFR85_RS28380	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
DFR85_RS28390	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DFR85_RS28400	ENOG4107RGD	Major Facilitator superfamily
DFR85_RS28435	ENOG4105CXK	mandelate racemase muconate lactonizing
DFR85_RS28470	ENOG4105DRR	Transcriptional regulator, GntR family
DFR85_RS28475	ENOG4105DIA	mandelate racemase muconate lactonizing
DFR85_RS28480	ENOG4105CTX	dehydratase
DFR85_RS28485	ENOG4105VP7	SAF domain protein
DFR85_RS28490	ENOG4105C54	Major Facilitator superfamily
DFR85_RS28495	ENOG4107QNK	)-transporter
DFR85_RS28500	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
DFR85_RS28505	ENOG4105C26	Dehydrogenase
DFR85_RS28510	ENOG4105CXK	mandelate racemase muconate lactonizing
DFR85_RS28515	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
DFR85_RS28520	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
DFR85_RS28525	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
DFR85_RS28550	ENOG4108IJ9	(ABC) transporter
DFR85_RS28580	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DFR85_RS28620	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DFR85_RS28630	ENOG4105DF9	Lipoate-protein, ligase
DFR85_RS28635	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
DFR85_RS28640	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
DFR85_RS28670	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
DFR85_RS28675	ENOG4105CSH	Transporter
DFR85_RS28685	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
DFR85_RS28750	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
DFR85_RS28755	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DFR85_RS28805	ENOG4108IEG	Formate dehydrogenase Alpha subunit
DFR85_RS28820	ENOG4105CSH	Transporter
DFR85_RS28835	ENOG41080XP	Cbs domain
DFR85_RS28915	ENOG4105DCI	Phosphohydrolase
DFR85_RS28970	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
DFR85_RS28980	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
DFR85_RS29050	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
DFR85_RS29135	ENOG4105C0D	helicase
DFR85_RS29175	ENOG4107QRT	dEAD DEAH box helicase
DFR85_RS29190	ENOG4107QPV	Serine Threonine protein kinase
DFR85_RS29240	ENOG4107ZMQ	sugar fermentation stimulation protein
DFR85_RS29245	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
DFR85_RS29280	ENOG4105C54	Major Facilitator superfamily
DFR85_RS29330	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
DFR85_RS29380	ENOG4105D3R	alkyl hydroperoxide reductase
DFR85_RS29390	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
DFR85_RS29500	ENOG4107V8H	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DFR85_RS29570	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DFR85_RS29580	ENOG4105C8H	hydrogenase maturation protein Hypf
DFR85_RS29655	ENOG4105C1G	acyl-Coa dehydrogenase
DFR85_RS29665	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DFR85_RS29680	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR85_RS29695	ENOG4105QAX	Iron-sulfur
DFR85_RS29700	ENOG4105EJ5	oxidoreductase gamma subunit
DFR85_RS29705	ENOG4105WGB	oxidoreductase, delta subunit
DFR85_RS29710	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
DFR85_RS29715	ENOG4105DDK	oxidoreductase, beta subunit
DFR85_RS29735	ENOG4105CIG	ABC transporter
DFR85_RS29765	ENOG4105CJ1	ABC, transporter
DFR85_RS29775	ENOG4105CS1	NAD(P)H quinone oxidoreductase
DFR85_RS29800	ENOG4108IEG	Formate dehydrogenase Alpha subunit
DFR85_RS29810	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
DFR85_RS29845	ENOG4105DIK	(ABC) transporter
DFR85_RS29895	ENOG4105C8Y	Acetylornithine aminotransferase
DFR85_RS29900	ENOG4105C1G	acyl-Coa dehydrogenase
DFR85_RS29950	ENOG4105E3S	small subunit
DFR85_RS29960	ENOG4105KVH	Transcriptional regulator
DFR85_RS30015	ENOG4105CUB	amino acid
DFR85_RS30055	ENOG4105E3S	small subunit
DFR85_RS30085	ENOG4105CA9	Pyruvate kinase
DFR85_RS30100	ENOG4105D7N	magnesium and cobalt transport protein CorA
DFR85_RS30130	ENOG4105D65	subunit l
DFR85_RS30135	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DFR85_RS30140	ENOG4105C57	major facilitator superfamily
DFR85_RS30145	ENOG41067TZ	transcriptional regulator, MarR family
DFR85_RS30165	ENOG4105VG1	fes assembly suf system protein
DFR85_RS30230	ENOG4105C26	Dehydrogenase
DFR85_RS30235	ENOG4105C7K	acetolactate synthase
DFR85_RS30275	ENOG4105CHR	reductase
DFR85_RS30280	ENOG4108FN7	Aldo keto reductase
DFR85_RS30290	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
DFR85_RS30295	ENOG4108BSC	Methyltransferase
DFR85_RS30300	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DFR85_RS30310	ENOG4105CJ1	ABC, transporter
DFR85_RS30345	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DFR85_RS30370	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DFR85_RS30375	ENOG41067TZ	transcriptional regulator, MarR family
DFR85_RS30395	ENOG4105C26	Dehydrogenase
DFR85_RS30410	ENOG4105DTQ	mandelate racemase muconate lactonizing
DFR85_RS30425	ENOG4105E39	Enoyl-CoA hydratase
DFR85_RS30430	ENOG4105C1G	acyl-Coa dehydrogenase
DFR85_RS30435	ENOG4105CEY	Amp-dependent synthetase and ligase
DFR85_RS30470	ENOG4105BZJ	Electron transfer flavoprotein
DFR85_RS30545	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DFR85_RS30550	ENOG4105EDK	PfkB domain protein
DFR85_RS30555	ENOG4105C26	Dehydrogenase
DFR85_RS30565	ENOG4105CEY	Amp-dependent synthetase and ligase
DFR85_RS30600	ENOG4106A3M	Cytochrome p-450
DFR85_RS30605	ENOG4105C28	cystathionine
DFR85_RS30610	ENOG4105CPP	Dehydrogenase, E1 component
DFR85_RS30615	ENOG4107RUY	(E1 component), alpha subunit
DFR85_RS30620	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DFR85_RS30625	ENOG4105CPQ	Dehydrogenase
DFR85_RS30640	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
DFR85_RS30655	ENOG4105K4P	CoA-binding domain protein
DFR85_RS30680	ENOG4105CQB	FAD linked oxidase domain protein
DFR85_RS30715	ENOG4105EWK	phytoene
DFR85_RS30720	ENOG4107QP3	malate synthase g
DFR85_RS30750	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR85_RS30775	ENOG4105E39	Enoyl-CoA hydratase
DFR85_RS30795	ENOG4105CXK	mandelate racemase muconate lactonizing
DFR85_RS30800	ENOG4105CEY	Amp-dependent synthetase and ligase
DFR85_RS30805	ENOG4105CHR	reductase
DFR85_RS30810	ENOG4105C54	Major Facilitator superfamily
DFR85_RS30820	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
DFR85_RS30830	ENOG4105DA5	(ABC) transporter
DFR85_RS30870	ENOG41083I7	UPF0145 protein
DFR85_RS30900	ENOG4105CSH	Transporter
DFR85_RS30910	ENOG4105C54	Major Facilitator superfamily
DFR85_RS30915	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
DFR85_RS30985	ENOG41079KZ	Major Facilitator Superfamily
DFR85_RS30990	ENOG4105CXK	mandelate racemase muconate lactonizing
DFR85_RS31010	ENOG4105J0Q	Transcriptional regulator
DFR85_RS31015	ENOG4108JPW	Aminotransferase
DFR85_RS31025	ENOG4105D49	3-dehydroquinate synthase
DFR85_RS31035	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
DFR85_RS31085	ENOG41067KJ	GYD family
DFR85_RS31115	ENOG4105CNW	domain protein
DFR85_RS31125	ENOG4105C6K	Malic enzyme
DFR85_RS31150	ENOG4105CHU	acetyl-coa acetyltransferase
DFR85_RS31175	ENOG4105CEY	Amp-dependent synthetase and ligase
DFR85_RS31205	ENOG4108UKI	Enoyl-CoA hydratase
DFR85_RS31210	ENOG4105E39	Enoyl-CoA hydratase
DFR85_RS31225	ENOG4105DZS	Phenylacetate-CoA ligase
DFR85_RS31240	ENOG4105ERH	Fumarylacetoacetate hydrolase
DFR85_RS31250	ENOG4105EFA	4-hydroxyphenylacetate
DFR85_RS31290	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR85_RS31305	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DFR85_RS31320	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR85_RS31345	ENOG4105C54	Major Facilitator superfamily
DFR85_RS31350	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DFR85_RS31370	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
DFR85_RS31380	ENOG41084XP	SirA-like domain-containing protein
DFR85_RS31450	ENOG4105C2X	Arabinose 5-phosphate isomerase
DFR85_RS31465	ENOG4105C10	Electron transfer flavoprotein
DFR85_RS31470	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR85_RS31515	ENOG4107QN2	dihydrolipoyl dehydrogenase
DFR85_RS31525	ENOG4105CB2	alcohol dehydrogenase
DFR85_RS31535	ENOG4105D3R	alkyl hydroperoxide reductase
DFR85_RS31545	ENOG4105C1G	acyl-Coa dehydrogenase
DFR85_RS31590	ENOG4107RQ2	Cytochrome c oxidase, subunit I
DFR85_RS31650	ENOG4105BZN	citrate synthase
DFR85_RS31655	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DFR85_RS31660	ENOG4105CR4	methylisocitrate lyase
DFR85_RS31665	ENOG4105DXD	2-methylcitrate dehydratase