locus-tag	class	description
AHOS_RS00015	COG2154	pterin-4-alpha-carbinolamine dehydratase
AHOS_RS00040	COG0330	HflC and HflK could
AHOS_RS00065	COG0308	aminopeptidase N
AHOS_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
AHOS_RS00110	COG1331	Highly conserved protein containing a thioredoxin domain
AHOS_RS00150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AHOS_RS00155	COG0438	transferase activity, transferring glycosyl groups
AHOS_RS00175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AHOS_RS00180	COG1024	Enoyl-CoA hydratase
AHOS_RS00225	COG1252	NADH dehydrogenase
AHOS_RS00235	COG1192	Involved in chromosome partitioning
AHOS_RS00250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AHOS_RS00255	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AHOS_RS00265	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AHOS_RS00315	COG1111	helicase
AHOS_RS00315	COG1205	dead DEAH box helicase
AHOS_RS00385	COG2226	methyltransferase
AHOS_RS00390	COG0477	Major facilitator Superfamily
AHOS_RS00405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AHOS_RS00405	COG0301	tRNA thio-modification
AHOS_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHOS_RS00440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHOS_RS00450	COG1013	pyruvate-flavodoxin oxidoreductase activity
AHOS_RS00455	COG0674	pyruvate-flavodoxin oxidoreductase activity
AHOS_RS00500	COG4555	ABC transporter
AHOS_RS00550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AHOS_RS00580	COG0477	Major facilitator Superfamily
AHOS_RS00630	COG0489	protein tyrosine kinase activity
AHOS_RS00640	COG0823	Involved in the tonB-independent uptake of proteins
AHOS_RS00640	COG4946	Tricorn protease homolog
AHOS_RS00640	COG1506	peptidase
AHOS_RS00650	COG1573	uracil-dna glycosylase
AHOS_RS00680	COG0586	Pfam SNARE associated Golgi protein
AHOS_RS00695	COG1028	Short-chain dehydrogenase reductase Sdr
AHOS_RS00725	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AHOS_RS00725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AHOS_RS00840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AHOS_RS00850	COG0095	Lipoate-protein ligase
AHOS_RS00870	COG0601	transmembrane transport
AHOS_RS00875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHOS_RS00880	COG0444	Belongs to the ABC transporter superfamily
AHOS_RS00885	COG4608	Belongs to the ABC transporter superfamily
AHOS_RS00950	COG0495	leucyl-tRNA aminoacylation
AHOS_RS00965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AHOS_RS00980	COG2814	Major facilitator Superfamily
AHOS_RS01020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AHOS_RS01115	COG1702	phosphate starvation-inducible protein PhoH
AHOS_RS01130	COG0375	protein maturation
AHOS_RS01195	COG1252	NADH dehydrogenase
AHOS_RS01215	COG0437	4 iron, 4 sulfur cluster binding
AHOS_RS01220	COG0243	molybdopterin cofactor binding
AHOS_RS01250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AHOS_RS01270	COG2009	succinate dehydrogenase
AHOS_RS01320	COG2217	Heavy metal translocating P-type atpase
AHOS_RS01350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AHOS_RS01355	COG4948	Mandelate Racemase Muconate Lactonizing
AHOS_RS01375	COG3387	PFAM Glycoside hydrolase 15-related
AHOS_RS01380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AHOS_RS01400	COG2226	methyltransferase
AHOS_RS01405	COG0531	amino acid
AHOS_RS01420	COG1012	belongs to the aldehyde dehydrogenase family
AHOS_RS01475	COG2723	6-phospho-beta-galactosidase activity
AHOS_RS01490	COG1175	transmembrane transport
AHOS_RS01495	COG3833	ABC-type maltose transport systems, permease component
AHOS_RS01500	COG3842	ATPase activity
AHOS_RS01510	COG0459	protein refolding
AHOS_RS01530	COG1305	Transglutaminase-like
AHOS_RS01535	COG2308	Evidence 4 Homologs of previously reported genes of
AHOS_RS01560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AHOS_RS01560	COG0674	pyruvate-flavodoxin oxidoreductase activity
AHOS_RS01565	COG1013	pyruvate-flavodoxin oxidoreductase activity
AHOS_RS01575	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AHOS_RS01575	COG0517	IMP dehydrogenase activity
AHOS_RS01580	COG0372	Belongs to the citrate synthase family
AHOS_RS01590	COG1131	(ABC) transporter
AHOS_RS01605	COG1960	acyl-CoA dehydrogenase activity
AHOS_RS01615	COG0039	L-malate dehydrogenase activity
AHOS_RS01640	COG0673	inositol 2-dehydrogenase activity
AHOS_RS01645	COG2271	Major facilitator Superfamily
AHOS_RS01650	COG2721	sulfolactate sulfo-lyase activity
AHOS_RS01655	COG2721	sulfolactate sulfo-lyase activity
AHOS_RS01665	COG1802	Transcriptional regulator
AHOS_RS01670	COG2814	Major facilitator Superfamily
AHOS_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
AHOS_RS01680	COG1012	belongs to the aldehyde dehydrogenase family
AHOS_RS01685	COG4948	Mandelate Racemase Muconate Lactonizing
AHOS_RS01690	COG3386	PFAM SMP-30 Gluconolaconase
AHOS_RS01715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AHOS_RS01720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AHOS_RS01745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHOS_RS01760	COG4608	Belongs to the ABC transporter superfamily
AHOS_RS01765	COG0444	Belongs to the ABC transporter superfamily
AHOS_RS01770	COG0601	transmembrane transport
AHOS_RS01995	COG1132	(ABC) transporter
AHOS_RS02000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AHOS_RS02020	COG2002	toxin-antitoxin pair type II binding
AHOS_RS02115	COG2814	Major facilitator Superfamily
AHOS_RS02130	COG0519	Catalyzes the synthesis of GMP from XMP
AHOS_RS02145	COG1473	amidohydrolase
AHOS_RS02175	COG1953	Uracil, thiamine, allantoin
AHOS_RS02195	COG1505	serine-type exopeptidase activity
AHOS_RS02205	COG1522	sequence-specific DNA binding
AHOS_RS02210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AHOS_RS02225	COG2814	Major facilitator Superfamily
AHOS_RS02230	COG0671	phosphoesterase, PA-phosphatase related
AHOS_RS02245	COG0531	amino acid
AHOS_RS02280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AHOS_RS02295	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AHOS_RS02305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AHOS_RS02310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AHOS_RS02320	COG2062	phosphohistidine phosphatase, SixA
AHOS_RS02330	COG2271	Major facilitator Superfamily
AHOS_RS02335	COG1473	amidohydrolase
AHOS_RS02350	COG1011	Hydrolase
AHOS_RS02360	COG0477	Major facilitator Superfamily
AHOS_RS02415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHOS_RS02440	COG1960	acyl-CoA dehydrogenase activity
AHOS_RS02445	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AHOS_RS02480	COG2222	sugar isomerase
AHOS_RS02485	COG0215	cysteine-tRNA ligase activity
AHOS_RS02490	COG1051	belongs to the nudix hydrolase family
AHOS_RS02500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AHOS_RS02510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AHOS_RS02520	COG1573	uracil-dna glycosylase
AHOS_RS02550	COG0475	glutathione-regulated potassium exporter activity
AHOS_RS02555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AHOS_RS02570	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AHOS_RS02575	COG1703	isobutyryl-CoA mutase activity
AHOS_RS02605	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AHOS_RS02610	COG1881	PFAM PEBP family protein
AHOS_RS02620	COG2255	four-way junction helicase activity
AHOS_RS02625	COG0315	cyclic pyranopterin monophosphate synthase activity
AHOS_RS02680	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AHOS_RS02705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AHOS_RS02710	COG1444	tRNA N-acetyltransferase activity
AHOS_RS02730	COG0589	response to stress
AHOS_RS02735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHOS_RS02740	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AHOS_RS02740	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AHOS_RS02745	COG0009	L-threonylcarbamoyladenylate synthase
AHOS_RS02750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHOS_RS02755	COG2379	hydroxypyruvate reductase
AHOS_RS02765	COG1321	iron dependent repressor
AHOS_RS02785	COG2226	methyltransferase
AHOS_RS02800	COG0303	'Molybdopterin
AHOS_RS02805	COG0746	molybdenum cofactor guanylyltransferase activity
AHOS_RS02820	COG0402	S-adenosylhomocysteine deaminase activity
AHOS_RS02850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AHOS_RS02895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AHOS_RS02910	COG1201	RNA secondary structure unwinding
AHOS_RS02915	COG3620	sequence-specific DNA binding
AHOS_RS02915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AHOS_RS02915	COG0617	tRNA 3'-terminal CCA addition
AHOS_RS02940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AHOS_RS02945	COG1546	Belongs to the CinA family
AHOS_RS02945	COG1058	Belongs to the CinA family
AHOS_RS02965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AHOS_RS02970	COG0024	Methionine aminopeptidase
AHOS_RS02995	COG0561	phosphatase activity
AHOS_RS03000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHOS_RS03020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AHOS_RS03040	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AHOS_RS03045	COG0504	CTP synthase activity
AHOS_RS03060	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
AHOS_RS03090	COG2078	PFAM AMMECR1 domain protein
AHOS_RS03105	COG0717	Belongs to the dCTP deaminase family
AHOS_RS03110	COG1793	dna ligase
AHOS_RS03120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AHOS_RS03145	COG0181	hydroxymethylbilane synthase activity
AHOS_RS03150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AHOS_RS03155	COG0113	porphobilinogen synthase activity
AHOS_RS03160	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AHOS_RS03165	COG1648	precorrin-2 dehydrogenase activity
AHOS_RS03165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AHOS_RS03170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHOS_RS03180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHOS_RS03200	COG0585	pseudouridine synthase activity
AHOS_RS03205	COG0017	Asparaginyl-tRNA synthetase
AHOS_RS03225	COG0028	Belongs to the TPP enzyme family
AHOS_RS03240	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AHOS_RS03245	COG0371	Dehydrogenase
AHOS_RS03250	COG1047	Peptidyl-prolyl cis-trans
AHOS_RS03255	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AHOS_RS03290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AHOS_RS03295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AHOS_RS03315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AHOS_RS03320	COG0142	geranyltranstransferase activity
AHOS_RS03325	COG1304	FMN binding
AHOS_RS03330	COG0528	UMP kinase activity
AHOS_RS03340	COG1355	regulation of microtubule-based process
AHOS_RS03345	COG0052	Belongs to the universal ribosomal protein uS2 family
AHOS_RS03355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AHOS_RS03360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AHOS_RS03365	COG0200	Binds to the 23S rRNA
AHOS_RS03375	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AHOS_RS03380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AHOS_RS03385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AHOS_RS03405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AHOS_RS03415	COG0417	DNA replication proofreading
AHOS_RS03445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AHOS_RS03450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AHOS_RS03465	COG3276	selenocysteine insertion sequence binding
AHOS_RS03480	COG0023	Translation Initiation Factor
AHOS_RS03490	COG0010	Belongs to the arginase family
AHOS_RS03495	COG0423	glycine-tRNA ligase activity
AHOS_RS03525	COG0163	prenyltransferase activity
AHOS_RS03530	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
AHOS_RS03545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AHOS_RS03550	COG0515	serine threonine protein kinase
AHOS_RS03550	COG2815	serine threonine protein kinase
AHOS_RS03555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AHOS_RS03560	COG0667	Aldo Keto reductase
AHOS_RS03605	COG1110	DNA topoisomerase II activity
AHOS_RS03610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHOS_RS03615	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
AHOS_RS03630	COG0557	exoribonuclease II activity
AHOS_RS03665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AHOS_RS03680	COG1797	cobyrinic acid a,c-diamide synthase activity
AHOS_RS03695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AHOS_RS03695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AHOS_RS03705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AHOS_RS03735	COG1201	RNA secondary structure unwinding
AHOS_RS03745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AHOS_RS03750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AHOS_RS03755	COG2813	Specifically methylates the guanine in position
AHOS_RS03795	COG0051	transcription antitermination factor activity, RNA binding
AHOS_RS03805	COG0049	tRNA binding
AHOS_RS03830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHOS_RS03835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHOS_RS03840	COG0085	RNA polymerase activity
AHOS_RS03850	COG0281	malic enzyme
AHOS_RS03860	COG0105	UTP biosynthetic process
AHOS_RS03870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AHOS_RS03880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHOS_RS03885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AHOS_RS03895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AHOS_RS03900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AHOS_RS03915	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AHOS_RS03930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AHOS_RS03935	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AHOS_RS03940	COG1522	sequence-specific DNA binding
AHOS_RS03945	COG1605	Chorismate mutase
AHOS_RS03945	COG0077	Prephenate dehydratase
AHOS_RS03985	COG1051	belongs to the nudix hydrolase family
AHOS_RS03985	COG1056	cytidyltransferase-related domain
AHOS_RS03990	COG1607	acyl-coa hydrolase
AHOS_RS04035	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AHOS_RS04050	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AHOS_RS04060	COG1129	ABC transporter
AHOS_RS04065	COG1980	fructose-bisphosphate aldolase activity
AHOS_RS04090	COG0459	protein refolding
AHOS_RS04105	COG0124	histidyl-tRNA synthetase
AHOS_RS04125	COG0343	queuine tRNA-ribosyltransferase activity
AHOS_RS04140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHOS_RS04150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AHOS_RS04190	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AHOS_RS04225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AHOS_RS04230	COG2264	protein methyltransferase activity
AHOS_RS04235	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AHOS_RS04245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AHOS_RS04250	COG0012	GTP binding
AHOS_RS04290	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AHOS_RS04295	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AHOS_RS04325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AHOS_RS04330	COG0546	phosphoglycolate phosphatase activity
AHOS_RS04345	COG0473	3-isopropylmalate dehydrogenase activity
AHOS_RS04350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AHOS_RS04360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AHOS_RS04375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AHOS_RS04380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AHOS_RS04385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AHOS_RS04390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AHOS_RS04395	COG0255	Belongs to the universal ribosomal protein uL29 family
AHOS_RS04410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AHOS_RS04415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AHOS_RS04425	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AHOS_RS04435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AHOS_RS04440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AHOS_RS04460	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AHOS_RS04470	COG0200	Binds to the 23S rRNA
AHOS_RS04475	COG0201	protein transport
AHOS_RS04495	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AHOS_RS04555	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AHOS_RS04570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AHOS_RS04575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AHOS_RS04590	COG0189	ligase activity
AHOS_RS04595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AHOS_RS04600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AHOS_RS04605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AHOS_RS04625	COG0114	fumarate hydratase activity
AHOS_RS04630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AHOS_RS04640	COG0516	GMP reductase activity
AHOS_RS04640	COG0517	IMP dehydrogenase activity
AHOS_RS04670	COG0149	triose-phosphate isomerase activity
AHOS_RS04685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AHOS_RS04690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AHOS_RS04720	COG0515	serine threonine protein kinase
AHOS_RS04720	COG2815	serine threonine protein kinase
AHOS_RS04745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AHOS_RS04745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AHOS_RS04750	COG0517	IMP dehydrogenase activity
AHOS_RS04760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AHOS_RS04765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AHOS_RS04770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AHOS_RS04795	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AHOS_RS04820	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AHOS_RS04865	COG3264	Mechanosensitive ion channel
AHOS_RS04865	COG1196	nuclear chromosome segregation
AHOS_RS04895	COG0312	modulator of DNA gyrase
AHOS_RS04915	COG0037	tRNA processing
AHOS_RS04990	COG2409	Drug exporters of the RND superfamily
AHOS_RS05015	COG0489	protein tyrosine kinase activity
AHOS_RS05055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AHOS_RS05065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AHOS_RS05120	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AHOS_RS05125	COG3830	Belongs to the UPF0237 family
AHOS_RS05130	COG2848	UPF0210 protein
AHOS_RS05140	COG0438	transferase activity, transferring glycosyl groups
AHOS_RS05180	COG1584	GPR1 FUN34 yaaH family protein
AHOS_RS05185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AHOS_RS05200	COG2814	Major facilitator Superfamily
AHOS_RS05230	COG0438	transferase activity, transferring glycosyl groups
AHOS_RS05265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AHOS_RS05275	COG1131	(ABC) transporter
AHOS_RS05285	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AHOS_RS05330	COG0501	Belongs to the peptidase M48B family
AHOS_RS05350	COG0477	Major facilitator Superfamily
AHOS_RS05365	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AHOS_RS05380	COG1592	Rubrerythrin
AHOS_RS05410	COG0450	alkyl hydroperoxide reductase
AHOS_RS05420	COG1215	transferase activity, transferring glycosyl groups
AHOS_RS05430	COG0352	thiamine-phosphate diphosphorylase activity
AHOS_RS05430	COG0351	phosphomethylpyrimidine kinase
AHOS_RS05435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AHOS_RS05440	COG0123	including yeast histone deacetylase and acetoin utilization protein
AHOS_RS05485	COG0463	Glycosyl transferase, family 2
AHOS_RS05490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AHOS_RS05505	COG1063	alcohol dehydrogenase
AHOS_RS05525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AHOS_RS05525	COG0519	Catalyzes the synthesis of GMP from XMP
AHOS_RS05530	COG0501	Belongs to the peptidase M48B family
AHOS_RS05535	COG0517	IMP dehydrogenase activity
AHOS_RS05535	COG0516	GMP reductase activity
AHOS_RS05550	COG1830	Aldolase
AHOS_RS05570	COG0405	Gamma-glutamyltransferase
AHOS_RS05585	COG1444	tRNA N-acetyltransferase activity
AHOS_RS05605	COG0589	response to stress
AHOS_RS05620	COG0864	Transcriptional regulator
AHOS_RS05630	COG0460	homoserine dehydrogenase
AHOS_RS05635	COG0109	protoheme IX farnesyltransferase activity
AHOS_RS05645	COG1024	Enoyl-CoA hydratase
AHOS_RS05685	COG1250	3-hydroxyacyl-CoA dehydrogenase
AHOS_RS05695	COG0189	ligase activity
AHOS_RS05700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AHOS_RS05710	COG0165	Argininosuccinate lyase
AHOS_RS05715	COG0137	argininosuccinate synthase activity
AHOS_RS05730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AHOS_RS05735	COG0151	Belongs to the GarS family
AHOS_RS05740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AHOS_RS05745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AHOS_RS05750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AHOS_RS05755	COG0047	phosphoribosylformylglycinamidine synthase activity
AHOS_RS05760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AHOS_RS05765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHOS_RS05765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHOS_RS05770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AHOS_RS05810	COG0284	orotidine-5'-phosphate decarboxylase activity
AHOS_RS05815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AHOS_RS05820	COG0540	Belongs to the ATCase OTCase family
AHOS_RS05825	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AHOS_RS05840	COG0167	dihydroorotate dehydrogenase activity
AHOS_RS05855	COG2095	MarC family integral membrane protein
AHOS_RS05860	COG1522	sequence-specific DNA binding
AHOS_RS05875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AHOS_RS05880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AHOS_RS05885	COG2151	metal-sulfur cluster biosynthetic enzyme
AHOS_RS05895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AHOS_RS05905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AHOS_RS05910	COG0107	imidazoleglycerol-phosphate synthase activity
AHOS_RS05925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AHOS_RS05930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AHOS_RS05940	COG0495	leucyl-tRNA aminoacylation
AHOS_RS05945	COG2096	Adenosyltransferase
AHOS_RS05950	COG0037	tRNA processing
AHOS_RS05960	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AHOS_RS05975	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AHOS_RS05985	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AHOS_RS05990	COG0546	phosphoglycolate phosphatase activity
AHOS_RS05995	COG0028	Belongs to the TPP enzyme family
AHOS_RS06020	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AHOS_RS06025	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AHOS_RS06035	COG0442	prolyl-tRNA aminoacylation
AHOS_RS06055	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AHOS_RS06075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHOS_RS06105	COG0417	DNA replication proofreading
AHOS_RS06120	COG1260	myo-inositol-1-phosphate synthase
AHOS_RS06125	COG1007	ATP synthesis coupled electron transport
AHOS_RS06130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AHOS_RS06135	COG0713	ATP synthesis coupled electron transport
AHOS_RS06145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHOS_RS06150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AHOS_RS06155	COG0649	NAD binding
AHOS_RS06160	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHOS_RS06190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AHOS_RS06225	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AHOS_RS06230	COG0723	plastoquinol--plastocyanin reductase activity
AHOS_RS06240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AHOS_RS06245	COG0083	homoserine kinase activity
AHOS_RS06250	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AHOS_RS06255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AHOS_RS06260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AHOS_RS06265	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AHOS_RS06270	COG1605	Chorismate mutase
AHOS_RS06270	COG0077	Prephenate dehydratase
AHOS_RS06275	COG3958	Transketolase
AHOS_RS06280	COG3959	Transketolase, thiamine diphosphate binding domain
AHOS_RS06315	COG0539	negative regulation of cytoplasmic translation
AHOS_RS06370	COG0067	glutamate synthase
AHOS_RS06375	COG0069	glutamate synthase activity
AHOS_RS06455	COG1185	polyribonucleotide nucleotidyltransferase activity
AHOS_RS06495	COG0300	oxidoreductase activity
AHOS_RS06530	COG0535	radical SAM domain protein
AHOS_RS06535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AHOS_RS06540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AHOS_RS06540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AHOS_RS06550	COG0318	PFAM AMP-dependent synthetase and ligase
AHOS_RS06575	COG0302	gtp cyclohydrolase
AHOS_RS06585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AHOS_RS06600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AHOS_RS06665	COG0552	protein localization to endoplasmic reticulum
AHOS_RS06680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AHOS_RS06700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AHOS_RS06715	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AHOS_RS06720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AHOS_RS06740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AHOS_RS06755	COG0126	phosphoglycerate kinase activity
AHOS_RS06835	COG0396	ATPase activity
AHOS_RS06855	COG0509	glycine decarboxylation via glycine cleavage system
AHOS_RS06860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AHOS_RS06865	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AHOS_RS06870	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AHOS_RS06910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHOS_RS06915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AHOS_RS06930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AHOS_RS06970	COG0525	valine-tRNA ligase activity
AHOS_RS06975	COG0436	Aminotransferase
AHOS_RS06980	COG0134	indole-3-glycerol-phosphate synthase activity
AHOS_RS06985	COG0512	Glutamine amidotransferase of anthranilate synthase
AHOS_RS06985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AHOS_RS06990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AHOS_RS06995	COG0135	phosphoribosylanthranilate isomerase activity
AHOS_RS07005	COG0159	tryptophan synthase activity
AHOS_RS07010	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AHOS_RS07015	COG1254	Belongs to the acylphosphatase family
AHOS_RS07030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AHOS_RS07030	COG0574	Belongs to the PEP-utilizing enzyme family
AHOS_RS07045	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AHOS_RS07055	COG0527	aspartate kinase activity
AHOS_RS07060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AHOS_RS07075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AHOS_RS07110	COG0459	protein refolding
AHOS_RS07135	COG0018	arginyl-trna synthetase
AHOS_RS07155	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHOS_RS07170	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHOS_RS07175	COG0252	asparaginase activity
AHOS_RS07205	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AHOS_RS07255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AHOS_RS07255	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AHOS_RS07270	COG0154	amidase activity
AHOS_RS07280	COG1324	tolerance protein
AHOS_RS07290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AHOS_RS07315	COG1110	DNA topoisomerase II activity
AHOS_RS07325	COG0514	ATP-dependent DNA helicase (RecQ)
AHOS_RS07355	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AHOS_RS07360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AHOS_RS07370	COG2084	Dehydrogenase
AHOS_RS07380	COG1028	Short-chain dehydrogenase reductase Sdr
AHOS_RS07390	COG0528	UMP kinase activity
AHOS_RS07400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHOS_RS07470	COG2814	Major facilitator Superfamily
AHOS_RS07505	COG0426	domain, Protein
AHOS_RS07505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AHOS_RS07545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AHOS_RS07550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AHOS_RS07560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AHOS_RS07565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AHOS_RS07600	COG0004	ammonium transporteR
AHOS_RS07615	COG2235	arginine
AHOS_RS07635	COG0438	transferase activity, transferring glycosyl groups
AHOS_RS07645	COG0589	response to stress
AHOS_RS07670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AHOS_RS07680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AHOS_RS07695	COG0045	succinate-CoA ligase (ADP-forming) activity
AHOS_RS07715	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AHOS_RS07720	COG1078	dGTPase activity
AHOS_RS07755	COG1832	CoA-binding protein
AHOS_RS07760	COG0179	Fumarylacetoacetate (FAA) hydrolase
AHOS_RS07780	COG0530	calcium, potassium:sodium antiporter activity
AHOS_RS07790	COG3386	PFAM SMP-30 Gluconolaconase
AHOS_RS07800	COG1695	Transcriptional regulator
AHOS_RS07835	COG0697	spore germination
AHOS_RS07845	COG2814	Major facilitator Superfamily
AHOS_RS07850	COG1335	isochorismatase
AHOS_RS07875	COG1733	regulation of RNA biosynthetic process
AHOS_RS07885	COG2002	toxin-antitoxin pair type II binding
AHOS_RS07965	COG3511	phospholipase C
AHOS_RS07975	COG1122	ATPase activity
AHOS_RS08090	COG0813	purine-nucleoside phosphorylase activity
AHOS_RS08095	COG0730	response to heat
AHOS_RS08105	COG0531	amino acid
AHOS_RS08130	COG0535	radical SAM domain protein
AHOS_RS08135	COG0535	radical SAM domain protein
AHOS_RS08155	COG0644	oxidoreductase
AHOS_RS08165	COG2086	electron transfer activity
AHOS_RS08170	COG1960	acyl-CoA dehydrogenase activity
AHOS_RS08175	COG0243	molybdopterin cofactor binding
AHOS_RS08375	COG0463	Glycosyl transferase, family 2
AHOS_RS08450	COG1373	ATPase (AAA superfamily
AHOS_RS08470	COG1914	H( )-stimulated, divalent metal cation uptake system
AHOS_RS08475	COG2814	Major facilitator Superfamily
AHOS_RS08480	COG0589	response to stress
AHOS_RS08510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AHOS_RS08565	COG0477	Major facilitator Superfamily
AHOS_RS08605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AHOS_RS08630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AHOS_RS08640	COG0805	protein transport
AHOS_RS08695	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AHOS_RS08735	COG0778	Nitroreductase
AHOS_RS08750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AHOS_RS08765	COG0509	glycine decarboxylation via glycine cleavage system
AHOS_RS08770	COG0095	Lipoate-protein ligase
AHOS_RS08775	COG0509	glycine decarboxylation via glycine cleavage system
AHOS_RS08800	COG2048	Heterodisulfide reductase, subunit B
AHOS_RS08815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHOS_RS08830	COG0425	Belongs to the sulfur carrier protein TusA family
AHOS_RS08835	COG2210	Belongs to the sulfur carrier protein TusA family
AHOS_RS08845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHOS_RS08865	COG0123	including yeast histone deacetylase and acetoin utilization protein
AHOS_RS08885	COG1720	tRNA m6t6A37 methyltransferase activity
AHOS_RS08905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHOS_RS08930	COG1063	alcohol dehydrogenase
AHOS_RS08935	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AHOS_RS08945	COG3383	formate dehydrogenase (NAD+) activity
AHOS_RS08970	COG2814	Major facilitator Superfamily
AHOS_RS08970	COG0477	Major facilitator Superfamily
AHOS_RS08990	COG0531	amino acid
AHOS_RS09030	COG1131	(ABC) transporter
AHOS_RS09160	COG1401	restriction endodeoxyribonuclease activity
AHOS_RS09170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AHOS_RS09265	COG1131	(ABC) transporter
AHOS_RS09270	COG3842	ATPase activity
AHOS_RS09325	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AHOS_RS09375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHOS_RS09400	COG1720	tRNA m6t6A37 methyltransferase activity
AHOS_RS09425	COG0708	Exodeoxyribonuclease III
AHOS_RS09435	COG0602	queuosine metabolic process
AHOS_RS09500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AHOS_RS09535	COG1968	undecaprenyl-diphosphatase activity
AHOS_RS09570	COG1489	DNA binding
AHOS_RS09590	COG0656	L-ascorbic acid biosynthetic process
AHOS_RS09700	COG0531	amino acid
AHOS_RS09720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AHOS_RS09825	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AHOS_RS09835	COG3387	PFAM Glycoside hydrolase 15-related
AHOS_RS09845	COG0477	Major facilitator Superfamily
AHOS_RS09865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AHOS_RS10005	COG2271	Major facilitator Superfamily
AHOS_RS10065	COG0308	aminopeptidase N
AHOS_RS10100	COG1013	pyruvate-flavodoxin oxidoreductase activity
AHOS_RS10105	COG0674	pyruvate-flavodoxin oxidoreductase activity
AHOS_RS10120	COG0531	amino acid
AHOS_RS10125	COG2814	Major facilitator Superfamily
AHOS_RS10130	COG0277	FAD linked oxidase domain protein
AHOS_RS10160	COG4152	abc transporter atp-binding protein
AHOS_RS10215	COG1131	(ABC) transporter
AHOS_RS10270	COG1131	(ABC) transporter
AHOS_RS10285	COG0393	Putative heavy-metal-binding
AHOS_RS10290	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AHOS_RS10355	COG4139	cobalamin transport
AHOS_RS10360	COG1121	(ABC) transporter
AHOS_RS10420	COG3383	formate dehydrogenase (NAD+) activity
AHOS_RS10475	COG1131	(ABC) transporter
AHOS_RS10490	COG0071	Belongs to the small heat shock protein (HSP20) family
AHOS_RS10495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AHOS_RS10630	COG2860	membrane
AHOS_RS10635	COG0697	spore germination
AHOS_RS10665	COG1139	Iron-sulfur cluster binding protein
AHOS_RS10695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AHOS_RS10695	COG1042	CoA-binding domain protein
AHOS_RS10695	COG0045	succinate-CoA ligase (ADP-forming) activity
AHOS_RS10705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AHOS_RS10710	COG0531	amino acid
AHOS_RS10715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AHOS_RS10720	COG1063	alcohol dehydrogenase
AHOS_RS10730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AHOS_RS10750	COG1131	(ABC) transporter
AHOS_RS10765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AHOS_RS10770	COG0066	3-isopropylmalate dehydratase activity
AHOS_RS10775	COG0778	Nitroreductase
AHOS_RS10820	COG0708	Exodeoxyribonuclease III
AHOS_RS10835	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AHOS_RS10860	COG0157	Belongs to the NadC ModD family
AHOS_RS10865	COG0519	Catalyzes the synthesis of GMP from XMP
AHOS_RS10875	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AHOS_RS10905	COG1515	deoxyribonuclease V activity
AHOS_RS10910	COG1335	isochorismatase
AHOS_RS10920	COG0450	alkyl hydroperoxide reductase
AHOS_RS10935	COG0372	Belongs to the citrate synthase family
AHOS_RS10955	COG4581	dead DEAH box helicase
AHOS_RS10960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AHOS_RS10970	COG0439	Biotin carboxylase
AHOS_RS11000	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AHOS_RS11010	COG0756	dUTP diphosphatase activity
AHOS_RS11080	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AHOS_RS11085	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AHOS_RS11100	COG0569	domain protein
AHOS_RS11100	COG0189	ligase activity
AHOS_RS11105	COG1522	sequence-specific DNA binding
AHOS_RS11120	COG1446	asparaginase
AHOS_RS11155	COG0647	UMP catabolic process
AHOS_RS11160	COG1053	succinate dehydrogenase
AHOS_RS11170	COG2048	Heterodisulfide reductase, subunit B
AHOS_RS11180	COG2304	oxidoreductase activity
AHOS_RS11185	COG0714	Associated with various cellular activities
AHOS_RS11200	COG0303	'Molybdopterin
AHOS_RS11205	COG0083	homoserine kinase activity
AHOS_RS11210	COG0626	cystathionine gamma-synthase activity
AHOS_RS11250	COG0183	Belongs to the thiolase family
AHOS_RS11255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AHOS_RS11275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AHOS_RS11290	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AHOS_RS11305	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AHOS_RS11310	COG0351	phosphomethylpyrimidine kinase
AHOS_RS11345	COG1131	(ABC) transporter
AHOS_RS11375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHOS_RS11405	COG0720	synthase
AHOS_RS11420	COG0492	ferredoxin-NADP+ reductase activity
AHOS_RS11430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHOS_RS11445	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AHOS_RS11450	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AHOS_RS11450	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AHOS_RS11455	COG0346	lactoylglutathione lyase activity
AHOS_RS11460	COG0071	Belongs to the small heat shock protein (HSP20) family
AHOS_RS11485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AHOS_RS11505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AHOS_RS11505	COG1648	precorrin-2 dehydrogenase activity
AHOS_RS11540	COG0174	glutamine synthetase
AHOS_RS11545	COG1063	alcohol dehydrogenase
AHOS_RS11550	COG0430	RNA-3'-phosphate cyclase activity
AHOS_RS11560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHOS_RS11565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AHOS_RS11570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHOS_RS11580	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AHOS_RS11665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AHOS_RS11675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AHOS_RS11680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AHOS_RS11700	COG0456	acetyltransferase
AHOS_RS11705	COG0469	pyruvate kinase activity
AHOS_RS11735	COG0297	glycogen (starch) synthase activity
AHOS_RS11765	COG1250	3-hydroxyacyl-CoA dehydrogenase
AHOS_RS11770	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AHOS_RS11805	COG1063	alcohol dehydrogenase
AHOS_RS11825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AHOS_RS11830	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AHOS_RS11830	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AHOS_RS11885	COG0735	belongs to the Fur family
AHOS_RS11905	COG0517	IMP dehydrogenase activity
AHOS_RS11905	COG0617	tRNA 3'-terminal CCA addition
AHOS_RS11905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AHOS_RS11915	COG2062	phosphohistidine phosphatase, SixA
AHOS_RS11930	COG3118	belongs to the thioredoxin family
AHOS_RS11990	COG0492	ferredoxin-NADP+ reductase activity
AHOS_RS12005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AHOS_RS12025	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AHOS_RS12035	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AHOS_RS12055	COG0561	phosphatase activity
AHOS_RS12065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AHOS_RS12070	COG0537	adenosine 5'-monophosphoramidase activity
AHOS_RS12080	COG0494	nUDIX hydrolase
AHOS_RS12085	COG3253	May function as heme-dependent peroxidase
AHOS_RS12100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AHOS_RS12105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AHOS_RS12105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AHOS_RS12165	COG0538	isocitrate dehydrogenase activity
AHOS_RS12180	COG1215	transferase activity, transferring glycosyl groups
AHOS_RS12220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AHOS_RS12220	COG0543	2 iron, 2 sulfur cluster binding
AHOS_RS12270	COG1312	Catalyzes the dehydration of D-mannonate