locus-tag	class	description
DFR86_RS00060	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
DFR86_RS11955	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
DFR86_RS11970	ENOG4105E4P	ATPase (AAA
DFR86_RS11975	ENOG4108WUZ	(ABC) transporter
DFR86_RS11995	ENOG4108KUF	arsenical pump membrane protein
DFR86_RS12070	ENOG4108JIG	Anaerobic dehydrogenase
DFR86_RS12075	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DFR86_RS12115	ENOG4105EG2	ABC transporter, permease
DFR86_RS12145	ENOG4108DT4	serine threonine protein kinase
DFR86_RS12160	ENOG4107QRT	dEAD DEAH box helicase
DFR86_RS12215	ENOG4105C10	Electron transfer flavoprotein
DFR86_RS12250	ENOG4105DDK	oxidoreductase, beta subunit
DFR86_RS12255	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
DFR86_RS12260	ENOG4105WGB	oxidoreductase, delta subunit
DFR86_RS12270	ENOG4105C1G	acyl-Coa dehydrogenase
DFR86_RS12285	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DFR86_RS12320	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DFR86_RS12325	ENOG4105DZS	Phenylacetate-CoA ligase
DFR86_RS12335	ENOG4105CHU	acetyl-coa acetyltransferase
DFR86_RS12340	ENOG4105CGU	Enoyl-CoA hydratase
DFR86_RS12360	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DFR86_RS12390	ENOG4105IJY	hydroxylase
DFR86_RS12420	ENOG4107RRZ	synthase
DFR86_RS12480	ENOG4105E4P	ATPase (AAA
DFR86_RS12515	ENOG4105D38	putrescine abc transporter
DFR86_RS12520	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DFR86_RS12545	ENOG4105E4P	ATPase (AAA
DFR86_RS12625	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
DFR86_RS12635	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
DFR86_RS12650	ENOG4108SHN	Glycosyl transferase, family 2
DFR86_RS12675	ENOG4107QRS	glycosyltransferase group 2 family protein
DFR86_RS12685	ENOG4108RJ9	Glycosyl transferase, family 2
DFR86_RS12765	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
DFR86_RS12790	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR86_RS12815	ENOG4105C1G	acyl-Coa dehydrogenase
DFR86_RS12820	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR86_RS12830	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DFR86_RS12835	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DFR86_RS12840	ENOG4105C3U	ABC transporter
DFR86_RS12845	ENOG4108JQ7	(ABC) transporter
DFR86_RS12860	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DFR86_RS12925	ENOG4105CUB	amino acid
DFR86_RS12965	ENOG4108P62	biosynthesis protein (CbiG)
DFR86_RS12970	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
DFR86_RS12980	ENOG4105E4R	Precorrin-3B C17-methyltransferase
DFR86_RS12985	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
DFR86_RS13000	ENOG4105D2S	major facilitator superfamily
DFR86_RS13005	ENOG4107QY8	reductase
DFR86_RS13010	ENOG4107RQ2	Cytochrome c oxidase, subunit I
DFR86_RS13015	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DFR86_RS13030	ENOG4108RAC	Rubrerythrin
DFR86_RS13040	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
DFR86_RS13050	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DFR86_RS13055	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DFR86_RS13095	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DFR86_RS13100	ENOG4105DXD	2-methylcitrate dehydratase
DFR86_RS13105	ENOG4105CR4	methylisocitrate lyase
DFR86_RS13110	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DFR86_RS13115	ENOG4105BZN	citrate synthase
DFR86_RS13150	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
DFR86_RS13160	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
DFR86_RS13165	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DFR86_RS13195	ENOG4105CHR	reductase
DFR86_RS13215	ENOG4105C54	Major Facilitator superfamily
DFR86_RS13245	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
DFR86_RS13250	ENOG4105C9Q	fumarate hydratase class II
DFR86_RS13255	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DFR86_RS13285	ENOG4105FCD	Major Facilitator
DFR86_RS13345	ENOG4105EN6	Membrane
DFR86_RS13355	ENOG4108WUZ	(ABC) transporter
DFR86_RS13370	ENOG4105CD5	CoA-binding domain protein
DFR86_RS13380	ENOG4107QTZ	amino acid
DFR86_RS13385	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR86_RS13390	ENOG4105CPQ	Dehydrogenase
DFR86_RS13415	ENOG4108JJB	ABC transporter
DFR86_RS13430	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DFR86_RS13435	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DFR86_RS13440	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
DFR86_RS13470	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
DFR86_RS13475	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DFR86_RS13485	ENOG4105DWF	phosphomethylpyrimidine kinase
DFR86_RS13490	ENOG4105C5R	Aminotransferase
DFR86_RS13510	ENOG4105CGK	Exodeoxyribonuclease III
DFR86_RS13520	ENOG410641W	Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear
DFR86_RS13525	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
DFR86_RS13530	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
DFR86_RS13540	ENOG4105D3R	alkyl hydroperoxide reductase
DFR86_RS13555	ENOG4105BZN	citrate synthase
DFR86_RS13575	ENOG4105CQR	helicase
DFR86_RS13590	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DFR86_RS13610	ENOG4105CB5	ATP-dependent DNA helicase recG
DFR86_RS13640	ENOG4105DQU	oxidoreductase, subunit beta
DFR86_RS13650	ENOG4107QN2	dihydrolipoyl dehydrogenase
DFR86_RS13660	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR86_RS13680	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
DFR86_RS13695	ENOG41079KZ	Major Facilitator Superfamily
DFR86_RS13710	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
DFR86_RS13715	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DFR86_RS13725	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DFR86_RS13755	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
DFR86_RS13765	ENOG4105C1J	atp-dependent rna helicase
DFR86_RS13775	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
DFR86_RS13810	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
DFR86_RS13845	ENOG4107QJE	Chromosome Partitioning Protein
DFR86_RS13860	ENOG4105U3E	Transcriptional regulator
DFR86_RS13880	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DFR86_RS13890	ENOG4105CJ1	ABC, transporter
DFR86_RS13900	ENOG4108UKI	Enoyl-CoA hydratase
DFR86_RS13905	ENOG4107RQ2	Cytochrome c oxidase, subunit I
DFR86_RS13925	ENOG41088YS	Glycosyl transferase (Group 1
DFR86_RS13930	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DFR86_RS13970	ENOG4105C7Z	Conserved Protein
DFR86_RS13980	ENOG4105ETU	transcriptional activator (TenA
DFR86_RS14065	ENOG4105KZX	Pterin carbinolamine dehydratase
DFR86_RS14080	ENOG4108HMX	isocitrate dehydrogenase (NADP)
DFR86_RS14105	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
DFR86_RS14110	ENOG4105C01	Dihydroxy-acid dehydratase
DFR86_RS14135	ENOG4105C4K	Nad synthetase
DFR86_RS14140	ENOG4105C4K	Nad synthetase
DFR86_RS14165	ENOG4107JTW	chlorite dismutase
DFR86_RS14180	ENOG4107YU2	histidine triad (hIT) protein
DFR86_RS14185	ENOG4105D4A	Cell wall formation (By similarity)
DFR86_RS14195	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DFR86_RS14205	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DFR86_RS14210	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
DFR86_RS14265	ENOG41090R7	Ferric uptake
DFR86_RS14285	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DFR86_RS14360	ENOG4105HBR	Rna-binding protein
DFR86_RS14375	ENOG4105CAY	ferredoxin--nadp reductase
DFR86_RS14385	ENOG4105DXB	Major Facilitator superfamily
DFR86_RS14410	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
DFR86_RS14435	ENOG4108X4Q	Hydrolase
DFR86_RS14480	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DFR86_RS14485	ENOG4108I9Z	alcohol dehydrogenase
DFR86_RS14490	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DFR86_RS14510	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DFR86_RS14520	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
DFR86_RS14570	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DFR86_RS14575	ENOG4107XGZ	Hydrolase
DFR86_RS14585	ENOG4105CFI	type iii restriction protein res subunit
DFR86_RS14655	ENOG4108IYU	L-aspartate oxidase
DFR86_RS14660	ENOG4108Z4K	mutator MutT protein
DFR86_RS14670	ENOG4108RVA	ribokinase
DFR86_RS14675	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DFR86_RS14685	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
DFR86_RS14695	ENOG4105C5F	glutamine synthetase
DFR86_RS14730	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DFR86_RS14750	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DFR86_RS14765	ENOG4105EM7	Selenocysteine-specific translation elongation factor
DFR86_RS14775	ENOG4106943	Heat shock protein
DFR86_RS14790	ENOG4107XRV	hypoxanthine phosphoribosyltransferase
DFR86_RS14805	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR86_RS14810	ENOG4105ECY	inositol monophosphatase
DFR86_RS14815	ENOG4105C3M	thioredoxin reductase
DFR86_RS14830	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
DFR86_RS14860	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DFR86_RS14865	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
DFR86_RS14890	ENOG4108IUW	ABC transporter
DFR86_RS14900	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
DFR86_RS14930	ENOG4105DWF	phosphomethylpyrimidine kinase
DFR86_RS14935	ENOG4105DK2	UPF0207 protein
DFR86_RS14985	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DFR86_RS15030	ENOG4105C28	cystathionine
DFR86_RS15035	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DFR86_RS15040	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DFR86_RS15055	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
DFR86_RS15085	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
DFR86_RS15100	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
DFR86_RS15115	ENOG4105D44	asparaginase
DFR86_RS15130	ENOG4108VVK	transcriptional Regulator, AsnC
DFR86_RS15135	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DFR86_RS15140	ENOG4105CTB	Polyprenyl synthetase
DFR86_RS15150	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
DFR86_RS15155	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
DFR86_RS15185	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DFR86_RS15220	ENOG4108IUW	ABC transporter
DFR86_RS15245	ENOG4105EYF	MMPL domain protein
DFR86_RS15255	ENOG4105CIG	ABC transporter
DFR86_RS15315	ENOG4105CSH	Transporter
DFR86_RS15320	ENOG4105CNH	Multidrug resistance protein MdtL
DFR86_RS15325	ENOG4105DZP	Membrane-associated zinc metalloprotease
DFR86_RS15360	ENOG4107PP3	Acetylornithine deacetylase
DFR86_RS15365	ENOG41079KZ	Major Facilitator Superfamily
DFR86_RS15380	ENOG4105BZP	glycoside hydrolase 15-related
DFR86_RS15400	ENOG41066UM	arsR family transcriptional regulator
DFR86_RS15410	ENOG4107QN2	dihydrolipoyl dehydrogenase
DFR86_RS15420	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
DFR86_RS15425	ENOG4105FDK	ABC transporter
DFR86_RS15445	ENOG4105C54	Major Facilitator superfamily
DFR86_RS15465	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
DFR86_RS15505	ENOG4105CJ1	ABC, transporter
DFR86_RS15530	ENOG4107YZX	Universal stress protein
DFR86_RS15545	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DFR86_RS15560	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
DFR86_RS15565	ENOG4105DQU	oxidoreductase, subunit beta
DFR86_RS15580	ENOG4107Z6X	Transcriptional regulator
DFR86_RS15595	ENOG4105DA5	(ABC) transporter
DFR86_RS15600	ENOG4108JJB	ABC transporter
DFR86_RS15610	ENOG4105CUB	amino acid
DFR86_RS15625	ENOG4108IEG	Formate dehydrogenase Alpha subunit
DFR86_RS15635	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
DFR86_RS15725	ENOG4105DPX	Hydrogenase, large subunit
DFR86_RS15735	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
DFR86_RS15775	ENOG4105CQS	hydrogenase expression formation protein HypD
DFR86_RS15815	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DFR86_RS15835	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DFR86_RS15880	ENOG4105C57	major facilitator superfamily
DFR86_RS15920	ENOG4105EW9	transcriptional regulator AsnC family
DFR86_RS15930	ENOG4105CSH	Transporter
DFR86_RS15935	ENOG4105CQB	FAD linked oxidase domain protein
DFR86_RS15945	ENOG4105CYW	agmatinase
DFR86_RS15970	ENOG4108I5U	Uridine phosphorylase
DFR86_RS15980	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DFR86_RS15985	ENOG4105DZC	cytosine deaminase
DFR86_RS15995	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
DFR86_RS16035	ENOG4105C7W	Xanthine dehydrogenase
DFR86_RS16040	ENOG4105DZC	cytosine deaminase
DFR86_RS16045	ENOG4105CEU	Arginine dihydrolase
DFR86_RS16055	ENOG4107QTZ	amino acid
DFR86_RS16060	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DFR86_RS16090	ENOG4105DZC	cytosine deaminase
DFR86_RS16100	ENOG4108YZ9	Urea amidohydrolase subunit gamma
DFR86_RS16115	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
DFR86_RS16130	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DFR86_RS16145	ENOG4105CXK	mandelate racemase muconate lactonizing
DFR86_RS16160	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR86_RS16180	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
DFR86_RS16190	ENOG4105CXK	mandelate racemase muconate lactonizing
DFR86_RS16200	ENOG4105BZ1	(ABC) transporter
DFR86_RS16215	ENOG4108JQ7	(ABC) transporter
DFR86_RS16220	ENOG4105C3U	ABC transporter
DFR86_RS16235	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DFR86_RS16265	ENOG4105CE4	GlcNAc 6-P deacetylase
DFR86_RS16270	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DFR86_RS16290	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DFR86_RS16295	ENOG4105C3U	ABC transporter
DFR86_RS16300	ENOG4108JQ7	(ABC) transporter
DFR86_RS16315	ENOG4105C6K	Malic enzyme
DFR86_RS16330	ENOG4107R7I	amino acid
DFR86_RS16335	ENOG4105CA9	Pyruvate kinase
DFR86_RS16340	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
DFR86_RS16405	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
DFR86_RS16410	ENOG4106HK8	GPR1 FUN34 yaaH family protein
DFR86_RS16415	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DFR86_RS16430	ENOG4105EFA	4-hydroxyphenylacetate
DFR86_RS16440	ENOG4105CSH	Transporter
DFR86_RS16450	ENOG4105CTD	carboxy-peptidase
DFR86_RS16460	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
DFR86_RS16465	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
DFR86_RS16480	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR86_RS16485	ENOG4107RQ2	Cytochrome c oxidase, subunit I
DFR86_RS16550	ENOG4105C5X	domain protein
DFR86_RS16570	ENOG4107V8H	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DFR86_RS16585	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DFR86_RS16595	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DFR86_RS16600	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DFR86_RS16610	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DFR86_RS16635	ENOG4105CQB	FAD linked oxidase domain protein
DFR86_RS16670	ENOG4105BZP	glycoside hydrolase 15-related
DFR86_RS16725	ENOG4105EUB	pirin domain protein
DFR86_RS16730	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DFR86_RS16760	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DFR86_RS16765	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DFR86_RS16810	ENOG4105C54	Major Facilitator superfamily
DFR86_RS16830	ENOG4105C54	Major Facilitator superfamily
DFR86_RS16885	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DFR86_RS16895	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
DFR86_RS16910	ENOG4105C1G	acyl-Coa dehydrogenase
DFR86_RS16925	ENOG4108S4H	thioesterase Superfamily protein
DFR86_RS16945	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
DFR86_RS16955	ENOG41086CI	Bifunctional phosphoglucose phosphomannose isomerase
DFR86_RS16975	ENOG4105D82	Glutamate dehydrogenase
DFR86_RS16985	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DFR86_RS16990	ENOG4105CHR	reductase
DFR86_RS16995	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
DFR86_RS17025	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DFR86_RS17050	ENOG4105DJT	lAO AO transport system ATPase
DFR86_RS17060	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
DFR86_RS17080	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
DFR86_RS17085	ENOG4108V1U	phospholipid-binding protein
DFR86_RS17095	ENOG4105D1H	recombination factor protein RarA
DFR86_RS17100	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DFR86_RS17155	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DFR86_RS17180	ENOG4105C5I	Dehydrogenase
DFR86_RS17185	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
DFR86_RS17205	ENOG4107YZX	Universal stress protein
DFR86_RS17210	ENOG4107QN2	dihydrolipoyl dehydrogenase
DFR86_RS17215	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
DFR86_RS17220	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DFR86_RS17225	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR86_RS17230	ENOG4105D1Z	hydroxypyruvate reductase
DFR86_RS17240	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
DFR86_RS17270	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
DFR86_RS17275	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DFR86_RS17280	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
DFR86_RS17325	ENOG4107RQ2	Cytochrome c oxidase, subunit I
DFR86_RS17350	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DFR86_RS17375	ENOG4105CSM	endonuclease III
DFR86_RS17390	ENOG4107QRT	dEAD DEAH box helicase
DFR86_RS17420	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DFR86_RS17425	ENOG4105CEV	competence damage-inducible protein
DFR86_RS17430	ENOG4107S9D	Alpha beta hydrolase
DFR86_RS17445	ENOG4105E8R	UPF0173 metal-dependent hydrolase
DFR86_RS17480	ENOG4105CX6	glutaminyL-tRNA synthetase
DFR86_RS17485	ENOG4105XPM	ribosomal protein
DFR86_RS17500	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DFR86_RS17505	ENOG4105EAH	synthase
DFR86_RS17510	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
DFR86_RS17515	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DFR86_RS17525	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
DFR86_RS17540	ENOG4108UJD	30S ribosomal protein S9
DFR86_RS17545	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DFR86_RS17560	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
DFR86_RS17565	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DFR86_RS17570	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DFR86_RS17580	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
DFR86_RS17590	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DFR86_RS17600	ENOG4105CQ2	DNA polymerase
DFR86_RS17635	ENOG4105CRK	lysyL-tRNA synthetase
DFR86_RS17655	ENOG4105EM7	Selenocysteine-specific translation elongation factor
DFR86_RS17670	ENOG4108ZJT	translation initiation factor, Sui1
DFR86_RS17680	ENOG4105CYW	agmatinase
DFR86_RS17685	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
DFR86_RS17715	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
DFR86_RS17725	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
DFR86_RS17740	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DFR86_RS17745	ENOG4105D9P	serine threonine protein kinase
DFR86_RS17750	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DFR86_RS17755	ENOG4105CPC	Aldo Keto reductase
DFR86_RS17800	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
DFR86_RS17805	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR86_RS17810	ENOG4105E3H	phosphoglycerate mutase
DFR86_RS17825	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
DFR86_RS17835	ENOG4105EM7	Selenocysteine-specific translation elongation factor
DFR86_RS17860	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
DFR86_RS17875	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DFR86_RS17890	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
DFR86_RS17930	ENOG4107QRT	dEAD DEAH box helicase
DFR86_RS17945	ENOG4107Y49	methyltransferase
DFR86_RS17950	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DFR86_RS17955	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DFR86_RS17970	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DFR86_RS17980	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DFR86_RS17995	ENOG4105CHV	Transcription elongation factor NusA
DFR86_RS18005	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DFR86_RS18010	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DFR86_RS18015	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DFR86_RS18025	ENOG4105C6K	Malic enzyme
DFR86_RS18030	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DFR86_RS18050	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
DFR86_RS18060	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DFR86_RS18075	ENOG4105WCJ	ec 1.1.1.193
DFR86_RS18080	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DFR86_RS18095	ENOG4105C83	adenylosuccinate lyase
DFR86_RS18115	ENOG4105DZ0	fad dependent oxidoreductase
DFR86_RS18125	ENOG4105CQC	Prephenate dehydratase
DFR86_RS18130	ENOG4105C7B	Threonine dehydratase
DFR86_RS18150	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DFR86_RS18170	ENOG4105NAU	thioesterase Superfamily protein
DFR86_RS18215	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
DFR86_RS18245	ENOG4105FDK	ABC transporter
DFR86_RS18250	ENOG4107NFR	Fructose-1,6-bisphosphatase
DFR86_RS18275	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DFR86_RS18290	ENOG4105CUT	histidyl-tRNA synthetase
DFR86_RS18310	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
DFR86_RS18325	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR86_RS18335	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DFR86_RS18370	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
DFR86_RS18415	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DFR86_RS18420	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
DFR86_RS18430	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
DFR86_RS18435	ENOG4105C3G	gtp-binding protein
DFR86_RS18475	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
DFR86_RS18480	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
DFR86_RS18510	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DFR86_RS18530	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DFR86_RS18535	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DFR86_RS18545	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DFR86_RS18550	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DFR86_RS18560	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DFR86_RS18565	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DFR86_RS18570	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DFR86_RS18580	ENOG4107FF9	50s ribosomal protein l29
DFR86_RS18590	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DFR86_RS18600	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
DFR86_RS18610	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DFR86_RS18620	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DFR86_RS18625	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DFR86_RS18645	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DFR86_RS18655	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DFR86_RS18675	ENOG4105CAT	Cytidine monophosphate kinase
DFR86_RS18740	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DFR86_RS18760	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DFR86_RS18780	ENOG4108VA3	3-hexulose-6-phosphate synthase
DFR86_RS18785	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DFR86_RS18800	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
DFR86_RS18830	ENOG4105NBF	ammecr1 domain protein
DFR86_RS18850	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
DFR86_RS18860	ENOG4108DN8	FAD dependent oxidoreductase
DFR86_RS18885	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
DFR86_RS18890	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DFR86_RS18895	ENOG4105D52	delta-aminolevulinic acid dehydratase
DFR86_RS18900	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
DFR86_RS18905	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DFR86_RS18910	ENOG4105C2M	dna polymerase I
DFR86_RS18920	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR86_RS18945	ENOG4105C5S	asparaginyl-tRNA synthetase
DFR86_RS18970	ENOG4105C7K	acetolactate synthase
DFR86_RS18980	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
DFR86_RS18985	ENOG4108YZY	peptidylprolyl cis-trans isomerase
DFR86_RS18990	ENOG4108MDK	Dehydrogenase
DFR86_RS18995	ENOG4105CY0	Metallo-Beta-Lactamase
DFR86_RS19035	ENOG41080HJ	6-phospho 3-hexuloisomerase
DFR86_RS19050	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DFR86_RS19055	ENOG4107U4Q	acetylglutamate kinase
DFR86_RS19070	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DFR86_RS19075	ENOG4105C8Y	Acetylornithine aminotransferase
DFR86_RS19085	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DFR86_RS19105	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DFR86_RS19150	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
DFR86_RS19155	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
DFR86_RS19165	ENOG4105DU0	nucleoside hydrolase
DFR86_RS19185	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DFR86_RS19190	ENOG4107TPY	serine threonine protein kinase
DFR86_RS19195	ENOG4105KME	endoribonuclease L-psp
DFR86_RS19215	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
DFR86_RS19220	ENOG4105CJW	magnesium transporter
DFR86_RS19230	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR86_RS19285	ENOG4107QM5	aconitate hydratase
DFR86_RS19325	ENOG4105EGS	Mechanosensitive ion channel
DFR86_RS19360	ENOG4108R96	Methyltransferase, YaeB family
DFR86_RS19365	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
DFR86_RS19380	ENOG4107R56	PP-loop domain protein
DFR86_RS19395	ENOG4105C1J	atp-dependent rna helicase
DFR86_RS19455	ENOG4105EYF	MMPL domain protein
DFR86_RS19490	ENOG4105D1F	ATP-binding protein
DFR86_RS19530	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DFR86_RS19540	ENOG4107QZB	decarboxylase
DFR86_RS19570	ENOG4105CSH	Transporter
DFR86_RS19585	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR86_RS19605	ENOG4105VFE	sira family
DFR86_RS19640	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
DFR86_RS19660	ENOG4105VUC	UPF0237 protein
DFR86_RS19700	ENOG4105CPQ	Dehydrogenase
DFR86_RS19710	ENOG4105CJ1	ABC, transporter
DFR86_RS19720	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
DFR86_RS19740	ENOG4105CSH	Transporter
DFR86_RS19750	ENOG4105D0M	Protease HtpX homolog
DFR86_RS19755	ENOG4105DG4	malate L-lactate dehydrogenase
DFR86_RS19795	ENOG4105CND	Glycosyl transferase, family 2
DFR86_RS19805	ENOG4105DWF	phosphomethylpyrimidine kinase
DFR86_RS19810	ENOG4108RVA	ribokinase
DFR86_RS19815	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
DFR86_RS19855	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
DFR86_RS19870	ENOG4105D0M	Protease HtpX homolog
DFR86_RS19875	ENOG4105CPQ	Dehydrogenase
DFR86_RS19880	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
DFR86_RS19895	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DFR86_RS19900	ENOG4105D0M	Protease HtpX homolog
DFR86_RS19905	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DFR86_RS19910	ENOG41061GT	Aldolase
DFR86_RS19925	ENOG4105C2X	Arabinose 5-phosphate isomerase
DFR86_RS19935	ENOG4105RD7	BadF BadG BcrA BcrD
DFR86_RS19940	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
DFR86_RS19955	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
DFR86_RS19975	ENOG4107YZX	Universal stress protein
DFR86_RS19990	ENOG4105MRR	Transcriptional regulator (By similarity)
DFR86_RS20005	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
DFR86_RS20015	ENOG4105E39	Enoyl-CoA hydratase
DFR86_RS20055	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
DFR86_RS20065	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DFR86_RS20080	ENOG4105CH7	arginosuccinase
DFR86_RS20085	ENOG4105CDH	Citrulline--aspartate ligase
DFR86_RS20100	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
DFR86_RS20105	ENOG4105C12	Phosphoribosylglycinamide synthetase
DFR86_RS20120	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
DFR86_RS20125	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
DFR86_RS20135	ENOG4107QPR	SAICAR synthetase
DFR86_RS20140	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DFR86_RS20145	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DFR86_RS20150	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
DFR86_RS20165	ENOG4107QN2	dihydrolipoyl dehydrogenase
DFR86_RS20180	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
DFR86_RS20190	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
DFR86_RS20195	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DFR86_RS20200	ENOG4105CXT	aspartate transcarbamylase
DFR86_RS20205	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
DFR86_RS20215	ENOG4105CD3	dihydroorotase
DFR86_RS20220	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
DFR86_RS20240	ENOG4108VVK	transcriptional Regulator, AsnC
DFR86_RS20255	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DFR86_RS20260	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
DFR86_RS20265	ENOG4105VG1	fes assembly suf system protein
DFR86_RS20275	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
DFR86_RS20280	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
DFR86_RS20285	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DFR86_RS20290	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
DFR86_RS20295	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
DFR86_RS20300	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
DFR86_RS20305	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
DFR86_RS20320	ENOG4105C8T	Leucyl-tRNA synthetase
DFR86_RS20325	ENOG4108WBT	adenosyltransferase
DFR86_RS20330	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
DFR86_RS20340	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
DFR86_RS20355	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
DFR86_RS20365	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
DFR86_RS20370	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DFR86_RS20375	ENOG4105C7K	acetolactate synthase
DFR86_RS20400	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
DFR86_RS20405	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
DFR86_RS20430	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
DFR86_RS20435	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
DFR86_RS20460	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DFR86_RS20490	ENOG4105CQ2	DNA polymerase
DFR86_RS20500	ENOG4105CZA	synthase
DFR86_RS20505	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR86_RS20510	ENOG4105D65	subunit l
DFR86_RS20515	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR86_RS20525	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR86_RS20535	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR86_RS20540	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DFR86_RS20550	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
DFR86_RS20570	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DFR86_RS20575	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DFR86_RS20605	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
DFR86_RS20620	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
DFR86_RS20630	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DFR86_RS20635	ENOG4105E2X	shikimate dehydrogenase
DFR86_RS20640	ENOG4105D49	3-dehydroquinate synthase
DFR86_RS20645	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
DFR86_RS20650	ENOG4105CQC	Prephenate dehydratase
DFR86_RS20655	ENOG4108IUS	Transketolase
DFR86_RS20660	ENOG4108HHA	Transketolase
DFR86_RS20695	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DFR86_RS20720	ENOG4105EYU	Glutamine amido-transferase
DFR86_RS20725	ENOG4105CBC	glutamate synthase
DFR86_RS20750	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DFR86_RS20785	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DFR86_RS20795	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
DFR86_RS20810	ENOG4105M7V	2'-5' rna ligase
DFR86_RS20835	ENOG4105F38	ABC transporter, permease
DFR86_RS20845	ENOG4105EMU	Dehydrogenase
DFR86_RS20860	ENOG4105CIF	Ornithine Cyclodeaminase
DFR86_RS20880	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
DFR86_RS20890	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DFR86_RS20900	ENOG4105CEY	Amp-dependent synthetase and ligase
DFR86_RS20910	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DFR86_RS20925	ENOG4105EUJ	GTP cyclohydrolase i
DFR86_RS20950	ENOG4105C6T	cysteine synthase
DFR86_RS21015	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DFR86_RS21030	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DFR86_RS21035	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
DFR86_RS21040	ENOG4108VZM	50s ribosomal protein L10
DFR86_RS21050	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DFR86_RS21065	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
DFR86_RS21070	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DFR86_RS21090	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DFR86_RS21095	ENOG4107YZX	Universal stress protein
DFR86_RS21105	ENOG4105BZA	Phosphoglycerate kinase
DFR86_RS21150	ENOG4105C3K	feS assembly ATPase SufC
DFR86_RS21170	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DFR86_RS21180	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DFR86_RS21185	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DFR86_RS21225	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DFR86_RS21230	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DFR86_RS21245	ENOG4108JQ1	Dehydrogenase
DFR86_RS21285	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DFR86_RS21295	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DFR86_RS21300	ENOG4105DDQ	anthranilate synthase
DFR86_RS21305	ENOG4105CRQ	synthase (Component I)
DFR86_RS21310	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
DFR86_RS21320	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DFR86_RS21325	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DFR86_RS21330	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
DFR86_RS21340	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
DFR86_RS21355	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
DFR86_RS21360	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
DFR86_RS21365	ENOG4105CFH	Aspartokinase
DFR86_RS21370	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
DFR86_RS21375	ENOG4105DB7	PHP domain protein
DFR86_RS21385	ENOG4105DBV	ornithine carbamoyltransferase
DFR86_RS21445	ENOG4105C75	arginyL-tRNA synthetase
DFR86_RS21475	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DFR86_RS21480	ENOG4105HDK	L-asparaginase
DFR86_RS21510	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
DFR86_RS21560	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
DFR86_RS21575	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DFR86_RS21585	ENOG4105VF7	tolerance protein
DFR86_RS21595	ENOG4105CB5	ATP-dependent DNA helicase recG
DFR86_RS21620	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
DFR86_RS21665	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DFR86_RS21680	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DFR86_RS21700	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DFR86_RS21710	ENOG4107SDT	Homocitrate synthase
DFR86_RS21720	ENOG4107ZBH	radical SAM domain protein
DFR86_RS21775	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DFR86_RS21780	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DFR86_RS21790	ENOG4105C22	threonyL-tRNA synthetase
DFR86_RS21795	ENOG4107RF4	Phosphodiesterase
DFR86_RS21830	ENOG4107QYH	Arginine deiminase
DFR86_RS21840	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
DFR86_RS21845	ENOG4105BZU	Histidine kinase
DFR86_RS21855	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DFR86_RS21865	ENOG4107YZX	Universal stress protein
DFR86_RS21890	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
DFR86_RS21895	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DFR86_RS21900	ENOG4105C22	threonyL-tRNA synthetase
DFR86_RS21905	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DFR86_RS21915	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
DFR86_RS21920	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
DFR86_RS21970	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
DFR86_RS22015	ENOG4105FEU	K -dependent Na -Ca exchanger
DFR86_RS22025	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
DFR86_RS22090	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DFR86_RS22115	ENOG4105D3W	isochorismatase
DFR86_RS22125	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
DFR86_RS22170	ENOG4105E50	uracil-dna glycosylase
DFR86_RS22180	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
DFR86_RS22205	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DFR86_RS22220	ENOG41089UC	methyltransferase, type 11
DFR86_RS22225	ENOG4105C26	Dehydrogenase
DFR86_RS22235	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
DFR86_RS22245	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
DFR86_RS22255	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
DFR86_RS22265	ENOG4108JJB	ABC transporter
DFR86_RS22300	ENOG4108JPZ	Monovalent cation H antiporter subunit D
DFR86_RS22305	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR86_RS22310	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DFR86_RS22315	ENOG4107R30	NADH dehydrogenase
DFR86_RS22320	ENOG4107TDF	Formate hydrogenlyase subunit 4
DFR86_RS22340	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DFR86_RS22355	ENOG4107TSN	permease
DFR86_RS22360	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DFR86_RS22430	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DFR86_RS22450	ENOG4108FN7	Aldo keto reductase
DFR86_RS22495	ENOG4105DGU	Histone deacetylase
DFR86_RS22520	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
DFR86_RS22525	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
DFR86_RS22540	ENOG4107QN2	dihydrolipoyl dehydrogenase
DFR86_RS22555	ENOG41086B8	CoB-CoM heterodisulfide reductase
DFR86_RS22570	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DFR86_RS22595	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
DFR86_RS22605	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
DFR86_RS22615	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
DFR86_RS22625	ENOG4105D3R	alkyl hydroperoxide reductase
DFR86_RS22650	ENOG4108UR0	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DFR86_RS22655	ENOG4105DF9	Lipoate-protein, ligase
DFR86_RS22665	ENOG4105CS1	NAD(P)H quinone oxidoreductase
DFR86_RS22675	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
DFR86_RS22730	ENOG4107RWR	Sodium hydrogen exchanger
DFR86_RS22750	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
DFR86_RS22775	ENOG4108HJF	gCN5-related N-acetyltransferase
DFR86_RS22785	ENOG4105C59	p-type ATPase
DFR86_RS22790	ENOG4105D1H	recombination factor protein RarA
DFR86_RS22830	ENOG41084XP	SirA-like domain-containing protein
DFR86_RS22845	ENOG4105VFE	sira family
DFR86_RS22905	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
DFR86_RS22915	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
DFR86_RS22935	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DFR86_RS22945	ENOG4105CQB	FAD linked oxidase domain protein
DFR86_RS22960	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DFR86_RS22980	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
DFR86_RS22985	ENOG4105DDK	oxidoreductase, beta subunit
DFR86_RS22995	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
DFR86_RS23040	ENOG4105C4M	(Ubiquinol oxidase) subunit I
DFR86_RS23060	ENOG4107QTZ	amino acid
DFR86_RS23070	ENOG4105D2B	acyl-CoA dehydrogenase
DFR86_RS23080	ENOG4105CC9	acyl-Coa dehydrogenase
DFR86_RS23085	ENOG4105C10	Electron transfer flavoprotein
DFR86_RS23100	ENOG4105C2X	Arabinose 5-phosphate isomerase
DFR86_RS23130	ENOG4105C8Y	Acetylornithine aminotransferase
DFR86_RS23140	ENOG4108R3D	Electron transport complex
DFR86_RS23395	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family