locus-tag	class	description
ACRY_RS00070	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ACRY_RS00115	COG0187	DNA topoisomerase II activity
ACRY_RS00165	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ACRY_RS00245	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACRY_RS00260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACRY_RS00340	COG0535	radical SAM domain protein
ACRY_RS00570	COG0297	glycogen (starch) synthase activity
ACRY_RS00605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACRY_RS01090	COG2001	Belongs to the MraZ family
ACRY_RS01095	COG0275	rRNA processing
ACRY_RS01300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACRY_RS01575	COG3158	transport of potassium into the cell
ACRY_RS02165	COG0187	DNA topoisomerase II activity
ACRY_RS02345	COG0557	exoribonuclease II activity
ACRY_RS02400	COG0183	Belongs to the thiolase family
ACRY_RS02435	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACRY_RS02440	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ACRY_RS02445	COG1278	Cold shock
ACRY_RS02450	COG0789	Transcriptional regulator
ACRY_RS02455	COG0183	Belongs to the thiolase family
ACRY_RS02460	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACRY_RS02460	COG1024	Enoyl-CoA hydratase
ACRY_RS02465	COG1960	acyl-CoA dehydrogenase activity
ACRY_RS02480	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACRY_RS02490	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ACRY_RS02505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACRY_RS02510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACRY_RS02515	COG0235	Class ii aldolase
ACRY_RS02520	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ACRY_RS02525	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ACRY_RS02530	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACRY_RS02535	COG1396	sequence-specific DNA binding
ACRY_RS02540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACRY_RS02550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACRY_RS02560	COG3045	CreA protein
ACRY_RS02565	COG0138	bifunctional purine biosynthesis protein purh
ACRY_RS02575	COG0187	DNA topoisomerase II activity
ACRY_RS02580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACRY_RS02585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACRY_RS02600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACRY_RS02615	COG0557	exoribonuclease II activity
ACRY_RS02620	COG0793	Belongs to the peptidase S41A family
ACRY_RS02625	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACRY_RS02630	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACRY_RS02635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACRY_RS02645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACRY_RS02645	COG2010	Cytochrome c
ACRY_RS02660	COG0156	8-amino-7-oxononanoate synthase activity
ACRY_RS02665	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ACRY_RS02675	COG1192	Involved in chromosome partitioning
ACRY_RS02680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACRY_RS02680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACRY_RS02690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACRY_RS02695	COG0509	glycine decarboxylation via glycine cleavage system
ACRY_RS02700	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACRY_RS02700	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACRY_RS02710	COG0616	signal peptide processing
ACRY_RS02715	COG2001	Belongs to the MraZ family
ACRY_RS02720	COG0275	rRNA processing
ACRY_RS02735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACRY_RS02740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACRY_RS02745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACRY_RS02750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACRY_RS02760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACRY_RS02765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACRY_RS02770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACRY_RS02775	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACRY_RS02780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACRY_RS02785	COG0849	cell division
ACRY_RS02800	COG0658	competence protein
ACRY_RS02800	COG2333	competence protein COMEC
ACRY_RS02810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACRY_RS02840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACRY_RS02845	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ACRY_RS02850	COG0535	radical SAM domain protein
ACRY_RS02855	COG0535	radical SAM domain protein
ACRY_RS02860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACRY_RS02880	COG1335	isochorismatase
ACRY_RS02885	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS02890	COG0129	dihydroxy-acid dehydratase activity
ACRY_RS02900	COG0789	Transcriptional regulator
ACRY_RS02905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACRY_RS02910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACRY_RS02925	COG3327	negative regulation of DNA-templated transcription, initiation
ACRY_RS02940	COG3328	transposase activity
ACRY_RS02950	COG3293	Transposase
ACRY_RS02975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACRY_RS03020	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ACRY_RS03025	COG1562	ergosterol biosynthetic process
ACRY_RS03030	COG1562	ergosterol biosynthetic process
ACRY_RS03035	COG1215	transferase activity, transferring glycosyl groups
ACRY_RS03040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACRY_RS03050	COG2261	transglycosylase associated protein
ACRY_RS03075	COG0181	hydroxymethylbilane synthase activity
ACRY_RS03080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACRY_RS03085	COG0058	SHG alpha-glucan phosphorylase activity
ACRY_RS03090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACRY_RS03095	COG0297	glycogen (starch) synthase activity
ACRY_RS03105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACRY_RS03110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACRY_RS03115	COG1538	Outer membrane efflux protein
ACRY_RS03130	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ACRY_RS03135	COG0247	lactate metabolic process
ACRY_RS03140	COG3158	transport of potassium into the cell
ACRY_RS03155	COG1042	CoA-binding domain protein
ACRY_RS03155	COG0045	succinate-CoA ligase (ADP-forming) activity
ACRY_RS03155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACRY_RS03160	COG0697	spore germination
ACRY_RS03165	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACRY_RS03185	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACRY_RS03190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACRY_RS03200	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ACRY_RS03215	COG0556	nucleotide-excision repair
ACRY_RS03235	COG5328	Belongs to the UPF0262 family
ACRY_RS03240	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACRY_RS03250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACRY_RS03255	COG0564	pseudouridine synthase activity
ACRY_RS03270	COG0148	phosphopyruvate hydratase activity
ACRY_RS03280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACRY_RS03290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACRY_RS03300	COG2885	chlorophyll binding
ACRY_RS03300	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACRY_RS03305	COG2885	chlorophyll binding
ACRY_RS03305	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACRY_RS03310	COG2365	Tyrosine phosphatase family
ACRY_RS03325	COG0469	pyruvate kinase activity
ACRY_RS03335	COG3750	Belongs to the UPF0335 family
ACRY_RS03340	COG0113	porphobilinogen synthase activity
ACRY_RS03360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACRY_RS03365	COG1609	Transcriptional regulator
ACRY_RS03370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACRY_RS03370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACRY_RS03375	COG1105	Belongs to the carbohydrate kinase PfkB family
ACRY_RS03380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACRY_RS03380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACRY_RS03390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACRY_RS03400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACRY_RS03410	COG0477	Major facilitator Superfamily
ACRY_RS03415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACRY_RS03425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACRY_RS03430	COG0501	Belongs to the peptidase M48B family
ACRY_RS03435	COG0071	Belongs to the small heat shock protein (HSP20) family
ACRY_RS03470	COG1132	(ABC) transporter
ACRY_RS03485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACRY_RS03495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACRY_RS03500	COG4133	protoheme IX ABC transporter activity
ACRY_RS03505	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACRY_RS03510	COG0006	proline dipeptidase activity
ACRY_RS03520	COG2264	protein methyltransferase activity
ACRY_RS03525	COG0210	DNA helicase
ACRY_RS03530	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACRY_RS03535	COG2853	Lipoprotein
ACRY_RS03545	COG0779	Required for maturation of 30S ribosomal subunits
ACRY_RS03560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACRY_RS03565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACRY_RS03570	COG0009	L-threonylcarbamoyladenylate synthase
ACRY_RS03575	COG0438	transferase activity, transferring glycosyl groups
ACRY_RS03600	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACRY_RS03605	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACRY_RS03610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACRY_RS03630	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACRY_RS03640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACRY_RS03645	COG0625	glutathione transferase activity
ACRY_RS03650	COG0406	alpha-ribazole phosphatase activity
ACRY_RS03655	COG1454	alcohol dehydrogenase
ACRY_RS03670	COG2226	methyltransferase
ACRY_RS03680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACRY_RS03690	COG1686	Belongs to the peptidase S11 family
ACRY_RS03700	COG0571	ribonuclease III activity
ACRY_RS03705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACRY_RS03710	COG1960	acyl-CoA dehydrogenase activity
ACRY_RS03715	COG1960	acyl-CoA dehydrogenase activity
ACRY_RS03720	COG0318	PFAM AMP-dependent synthetase and ligase
ACRY_RS03725	COG1024	Enoyl-CoA hydratase
ACRY_RS03725	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACRY_RS03740	COG0457	Tetratricopeptide repeat
ACRY_RS03770	COG0438	transferase activity, transferring glycosyl groups
ACRY_RS03780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACRY_RS03795	COG0776	regulation of translation
ACRY_RS03800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACRY_RS03805	COG0416	fatty acid biosynthetic process
ACRY_RS03810	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACRY_RS03840	COG0582	viral genome integration into host DNA
ACRY_RS03875	COG1484	DNA-dependent DNA replication
ACRY_RS03880	COG4584	PFAM Integrase catalytic
ACRY_RS03895	COG3328	transposase activity
ACRY_RS03910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACRY_RS03930	COG0110	maltose O-acetyltransferase activity
ACRY_RS03945	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ACRY_RS03960	COG3842	ATPase activity
ACRY_RS03975	COG1136	(ABC) transporter
ACRY_RS03985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACRY_RS03990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACRY_RS03995	COG0577	efflux transmembrane transporter activity
ACRY_RS03995	COG1136	(ABC) transporter
ACRY_RS04000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACRY_RS04025	COG2205	protein histidine kinase activity
ACRY_RS04055	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS04060	COG1129	ABC transporter
ACRY_RS04080	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ACRY_RS04090	COG0384	phenazine biosynthesis protein PhzF
ACRY_RS04100	COG0409	Hydrogenase expression formation protein
ACRY_RS04125	COG1773	rubredoxin
ACRY_RS04170	COG1575	Belongs to the MenA family. Type 1 subfamily
ACRY_RS04190	COG0243	molybdopterin cofactor binding
ACRY_RS04195	COG2897	thiosulfate sulfurtransferase activity
ACRY_RS04215	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ACRY_RS04235	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACRY_RS04235	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACRY_RS04240	COG2326	polyphosphate kinase activity
ACRY_RS04275	COG0072	phenylalanine-tRNA ligase activity
ACRY_RS04275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACRY_RS04280	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACRY_RS04285	COG2885	chlorophyll binding
ACRY_RS04295	COG0037	tRNA processing
ACRY_RS04300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACRY_RS04315	COG1185	polyribonucleotide nucleotidyltransferase activity
ACRY_RS04320	COG2807	transmembrane transport
ACRY_RS04330	COG2259	Doxx family
ACRY_RS04335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACRY_RS04340	COG0242	peptide deformylase activity
ACRY_RS04350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACRY_RS04355	COG0004	ammonium transporteR
ACRY_RS04360	COG1674	ftsk spoiiie
ACRY_RS04375	COG0352	thiamine-phosphate diphosphorylase activity
ACRY_RS04385	COG0463	Glycosyl transferase, family 2
ACRY_RS04385	COG0457	Tetratricopeptide repeat
ACRY_RS04410	COG1530	ribonuclease E activity
ACRY_RS04415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACRY_RS04420	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACRY_RS04425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACRY_RS04430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACRY_RS04435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACRY_RS04440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACRY_RS04445	COG0356	it plays a direct role in the translocation of protons across the membrane
ACRY_RS04455	COG1196	nuclear chromosome segregation
ACRY_RS04465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACRY_RS04480	COG1286	toxin biosynthetic process
ACRY_RS04485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACRY_RS04490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACRY_RS04500	COG0071	Belongs to the small heat shock protein (HSP20) family
ACRY_RS04505	COG0242	peptide deformylase activity
ACRY_RS04510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACRY_RS04515	COG0101	tRNA pseudouridine synthase activity
ACRY_RS04520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACRY_RS04540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACRY_RS04545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACRY_RS04555	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACRY_RS04560	COG0322	excinuclease ABC activity
ACRY_RS04585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACRY_RS04600	COG0424	maF-like protein
ACRY_RS04615	COG2983	Belongs to the UPF0260 family
ACRY_RS04635	COG1131	(ABC) transporter
ACRY_RS04640	COG2813	Specifically methylates the guanine in position
ACRY_RS04640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACRY_RS04645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACRY_RS04650	COG1605	Chorismate mutase
ACRY_RS04650	COG0077	Prephenate dehydratase
ACRY_RS04655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACRY_RS04660	COG0287	Prephenate dehydrogenase
ACRY_RS04665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACRY_RS04670	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACRY_RS04675	COG0670	Belongs to the BI1 family
ACRY_RS04680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACRY_RS04685	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACRY_RS04685	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACRY_RS04690	COG1660	Displays ATPase and GTPase activities
ACRY_RS04700	COG0745	RESPONSE REGULATOR receiver
ACRY_RS04705	COG2205	protein histidine kinase activity
ACRY_RS04710	COG2814	Major facilitator Superfamily
ACRY_RS04725	COG1069	ribulokinase activity
ACRY_RS04730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACRY_RS04760	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS04770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACRY_RS04775	COG0129	dihydroxy-acid dehydratase activity
ACRY_RS04780	COG0800	Aldolase
ACRY_RS04785	COG2814	Major facilitator Superfamily
ACRY_RS04800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACRY_RS04815	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACRY_RS04835	COG2050	protein possibly involved in aromatic compounds catabolism
ACRY_RS04850	COG4964	Belongs to the GSP D family
ACRY_RS04900	COG5001	Diguanylate cyclase
ACRY_RS04900	COG3300	MHYT domain
ACRY_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS04925	COG4689	acetoacetate decarboxylase
ACRY_RS04935	COG0768	penicillin binding
ACRY_RS04965	COG1070	Carbohydrate kinase
ACRY_RS04970	COG1879	ABC-type sugar transport system periplasmic component
ACRY_RS04980	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS04985	COG0776	regulation of translation
ACRY_RS04990	COG1091	dTDP-4-dehydrorhamnose reductase activity
ACRY_RS05000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACRY_RS05005	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACRY_RS05010	COG2080	2 iron, 2 sulfur cluster binding
ACRY_RS05020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACRY_RS05030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACRY_RS05055	COG0840	transmembrane signaling receptor activity
ACRY_RS05060	COG5001	Diguanylate cyclase
ACRY_RS05075	COG1199	ATP-dependent helicase activity
ACRY_RS05080	COG1573	uracil-dna glycosylase
ACRY_RS05090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACRY_RS05095	COG1758	RNA polymerase activity
ACRY_RS05105	COG0736	holo-[acyl-carrier-protein] synthase activity
ACRY_RS05110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACRY_RS05115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACRY_RS05120	COG0596	Alpha beta hydrolase
ACRY_RS05130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACRY_RS05145	COG1177	transmembrane transport
ACRY_RS05150	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACRY_RS05155	COG3842	ATPase activity
ACRY_RS05160	COG0686	Belongs to the AlaDH PNT family
ACRY_RS05175	COG0174	glutamine synthetase
ACRY_RS05185	COG0662	Cupin 2, conserved barrel domain protein
ACRY_RS05185	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ACRY_RS05210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACRY_RS05215	COG4988	ABC transporter
ACRY_RS05220	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACRY_RS05240	COG4178	(ABC) transporter
ACRY_RS05250	COG1566	PFAM secretion protein HlyD family protein
ACRY_RS05255	COG2814	Major facilitator Superfamily
ACRY_RS05260	COG1538	Outer membrane efflux protein
ACRY_RS05265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACRY_RS05270	COG0538	isocitrate dehydrogenase activity
ACRY_RS05275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACRY_RS05330	COG0784	Response regulator, receiver
ACRY_RS05330	COG4191	Histidine kinase
ACRY_RS05350	COG3800	Transcriptional regulator
ACRY_RS05350	COG1396	sequence-specific DNA binding
ACRY_RS05355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACRY_RS05360	COG0196	riboflavin kinase activity
ACRY_RS05365	COG2030	dehydratase
ACRY_RS05380	COG0477	Major facilitator Superfamily
ACRY_RS05385	COG1132	(ABC) transporter
ACRY_RS05400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACRY_RS05410	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ACRY_RS05425	COG1090	epimerase
ACRY_RS05435	COG0840	transmembrane signaling receptor activity
ACRY_RS05465	COG0651	ATP synthesis coupled electron transport
ACRY_RS05470	COG0649	NAD binding
ACRY_RS05475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS05495	COG1091	dTDP-4-dehydrorhamnose reductase activity
ACRY_RS05500	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ACRY_RS05505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ACRY_RS05510	COG1088	dTDP-glucose 4,6-dehydratase activity
ACRY_RS05520	COG0154	amidase activity
ACRY_RS05525	COG0415	Belongs to the DNA photolyase family
ACRY_RS05530	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS05535	COG0318	PFAM AMP-dependent synthetase and ligase
ACRY_RS05540	COG2079	MmgE PrpD family protein
ACRY_RS05550	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACRY_RS05555	COG1960	acyl-CoA dehydrogenase activity
ACRY_RS05560	COG1024	Enoyl-CoA hydratase
ACRY_RS05585	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACRY_RS05595	COG2814	Major facilitator Superfamily
ACRY_RS05605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACRY_RS05610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACRY_RS05615	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ACRY_RS05635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS05640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACRY_RS05655	COG1605	Chorismate mutase
ACRY_RS05655	COG0077	Prephenate dehydratase
ACRY_RS05660	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ACRY_RS05665	COG3474	cytochrome
ACRY_RS05670	COG0483	inositol monophosphate 1-phosphatase activity
ACRY_RS05680	COG0473	3-isopropylmalate dehydrogenase activity
ACRY_RS05685	COG0531	amino acid
ACRY_RS05695	COG1663	tetraacyldisaccharide 4'-kinase activity
ACRY_RS05700	COG1519	Transferase
ACRY_RS05725	COG1792	Involved in formation and maintenance of cell shape
ACRY_RS05740	COG0772	Belongs to the SEDS family
ACRY_RS05755	COG0318	PFAM AMP-dependent synthetase and ligase
ACRY_RS05765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACRY_RS05770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACRY_RS05810	COG2885	chlorophyll binding
ACRY_RS05825	COG1309	transcriptional regulator
ACRY_RS05830	COG0583	DNA-binding transcription factor activity
ACRY_RS05835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACRY_RS05850	COG0840	transmembrane signaling receptor activity
ACRY_RS05865	COG0765	amino acid transport
ACRY_RS05875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACRY_RS05935	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACRY_RS05940	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACRY_RS05975	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACRY_RS05990	COG2205	protein histidine kinase activity
ACRY_RS06000	COG0583	DNA-binding transcription factor activity
ACRY_RS06005	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS06010	COG3959	Transketolase, thiamine diphosphate binding domain
ACRY_RS06015	COG3958	Transketolase
ACRY_RS06020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ACRY_RS06025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ACRY_RS06040	COG1968	undecaprenyl-diphosphatase activity
ACRY_RS06045	COG0463	Glycosyl transferase, family 2
ACRY_RS06050	COG2166	iron-sulfur cluster assembly
ACRY_RS06055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACRY_RS06065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACRY_RS06070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACRY_RS06075	COG0758	DNA mediated transformation
ACRY_RS06090	COG0540	Belongs to the ATCase OTCase family
ACRY_RS06105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACRY_RS06125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACRY_RS06125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACRY_RS06155	COG0019	diaminopimelate decarboxylase activity
ACRY_RS06160	COG0165	Argininosuccinate lyase
ACRY_RS06165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACRY_RS06170	COG0137	argininosuccinate synthase activity
ACRY_RS06185	COG1160	GTP binding
ACRY_RS06205	COG0539	negative regulation of cytoplasmic translation
ACRY_RS06210	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACRY_RS06220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACRY_RS06235	COG1706	bacterial-type flagellum-dependent cell motility
ACRY_RS06250	COG0438	transferase activity, transferring glycosyl groups
ACRY_RS06270	COG0390	transport system, permease component
ACRY_RS06275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACRY_RS06280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACRY_RS06285	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACRY_RS06290	COG1573	uracil-dna glycosylase
ACRY_RS06305	COG3328	transposase activity
ACRY_RS06320	COG2963	transposase activity
ACRY_RS06340	COG4372	Transposase
ACRY_RS06345	COG3436	PFAM IS66 Orf2 family protein
ACRY_RS06350	COG2963	transposase activity
ACRY_RS06355	COG2801	Transposase and inactivated derivatives
ACRY_RS06375	COG3328	transposase activity
ACRY_RS06420	COG3328	transposase activity
ACRY_RS06450	COG3328	transposase activity
ACRY_RS06455	COG2801	Transposase and inactivated derivatives
ACRY_RS06500	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACRY_RS06505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACRY_RS06510	COG0351	phosphomethylpyrimidine kinase
ACRY_RS06515	COG1764	response to oxidative stress
ACRY_RS06520	COG1192	Involved in chromosome partitioning
ACRY_RS06525	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACRY_RS06540	COG1850	ribulose-bisphosphate carboxylase activity
ACRY_RS06545	COG4451	ribulose bisphosphate carboxylase, small
ACRY_RS06560	COG0402	S-adenosylhomocysteine deaminase activity
ACRY_RS06565	COG0259	pyridoxamine-phosphate oxidase activity
ACRY_RS06570	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACRY_RS06580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACRY_RS06585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACRY_RS06610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACRY_RS06615	COG3383	formate dehydrogenase (NAD+) activity
ACRY_RS06630	COG0583	DNA-binding transcription factor activity
ACRY_RS06635	COG1064	alcohol dehydrogenase
ACRY_RS06645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACRY_RS06655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACRY_RS06670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACRY_RS06675	COG1846	Transcriptional regulator
ACRY_RS06680	COG0745	RESPONSE REGULATOR receiver
ACRY_RS06700	COG0513	Belongs to the DEAD box helicase family
ACRY_RS06715	COG5001	Diguanylate cyclase
ACRY_RS06715	COG3300	MHYT domain
ACRY_RS06725	COG0358	DNA primase activity
ACRY_RS06730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACRY_RS06745	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACRY_RS06760	COG1999	signal sequence binding
ACRY_RS06775	COG1999	signal sequence binding
ACRY_RS06780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACRY_RS06785	COG0154	amidase activity
ACRY_RS06790	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACRY_RS06795	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACRY_RS06810	COG3772	lysozyme
ACRY_RS06860	COG1450	Type ii and iii secretion system protein
ACRY_RS06875	COG3166	PFAM Fimbrial assembly family protein
ACRY_RS06900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACRY_RS06930	COG0519	Catalyzes the synthesis of GMP from XMP
ACRY_RS06930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACRY_RS06935	COG0412	Dienelactone hydrolase
ACRY_RS06940	COG0494	nUDIX hydrolase
ACRY_RS06950	COG0793	Belongs to the peptidase S41A family
ACRY_RS06960	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACRY_RS06965	COG0084	hydrolase, TatD family'
ACRY_RS06970	COG1234	tRNA 3'-trailer cleavage
ACRY_RS06975	COG2309	aminopeptidase activity
ACRY_RS06980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACRY_RS06985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACRY_RS06990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACRY_RS06995	COG0505	Belongs to the CarA family
ACRY_RS07000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACRY_RS07005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACRY_RS07020	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACRY_RS07025	COG0740	serine-type endopeptidase activity
ACRY_RS07030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACRY_RS07040	COG0776	regulation of translation
ACRY_RS07055	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS07060	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS07065	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS07070	COG0649	NAD binding
ACRY_RS07075	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACRY_RS07085	COG1034	ATP synthesis coupled electron transport
ACRY_RS07090	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACRY_RS07095	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS07105	COG0713	ATP synthesis coupled electron transport
ACRY_RS07120	COG1007	ATP synthesis coupled electron transport
ACRY_RS07130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACRY_RS07145	COG0442	prolyl-tRNA aminoacylation
ACRY_RS07155	COG1136	(ABC) transporter
ACRY_RS07160	COG0657	acetylesterase activity
ACRY_RS07165	COG3431	PFAM Phosphate-starvation-inducible E
ACRY_RS07170	COG0488	(ABC) transporter
ACRY_RS07175	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ACRY_RS07180	COG0708	Exodeoxyribonuclease III
ACRY_RS07185	COG0316	Belongs to the HesB IscA family
ACRY_RS07190	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACRY_RS07195	COG0018	arginyl-trna synthetase
ACRY_RS07210	COG1994	Peptidase M50
ACRY_RS07215	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACRY_RS07220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACRY_RS07225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACRY_RS07230	COG0805	protein transport
ACRY_RS07235	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACRY_RS07255	COG0640	Transcriptional regulator
ACRY_RS07260	COG2022	thiamine diphosphate biosynthetic process
ACRY_RS07270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACRY_RS07270	COG2022	thiamine diphosphate biosynthetic process
ACRY_RS07275	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACRY_RS07280	COG5001	Diguanylate cyclase
ACRY_RS07280	COG3300	MHYT domain
ACRY_RS07290	COG2951	lytic endotransglycosylase activity
ACRY_RS07300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACRY_RS07330	COG0463	Glycosyl transferase, family 2
ACRY_RS07345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACRY_RS07350	COG0483	inositol monophosphate 1-phosphatase activity
ACRY_RS07355	COG3842	ATPase activity
ACRY_RS07395	COG3448	diguanylate cyclase activity
ACRY_RS07395	COG4175	Glycine betaine
ACRY_RS07400	COG1012	belongs to the aldehyde dehydrogenase family
ACRY_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACRY_RS07415	COG4311	Sarcosine oxidase, delta subunit
ACRY_RS07420	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACRY_RS07420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACRY_RS07430	COG1760	l-serine dehydratase
ACRY_RS07445	COG0247	lactate metabolic process
ACRY_RS07445	COG2181	nitrate reductase activity
ACRY_RS07450	COG1902	pentaerythritol trinitrate reductase activity
ACRY_RS07450	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACRY_RS07460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACRY_RS07475	COG3119	arylsulfatase activity
ACRY_RS07480	COG0583	DNA-binding transcription factor activity
ACRY_RS07485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACRY_RS07490	COG0527	aspartate kinase activity
ACRY_RS07495	COG2070	2-Nitropropane dioxygenase
ACRY_RS07505	COG1426	Protein conserved in bacteria
ACRY_RS07510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACRY_RS07515	COG0124	histidyl-tRNA synthetase
ACRY_RS07520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACRY_RS07525	COG2890	protein-(glutamine-N5) methyltransferase activity
ACRY_RS07545	COG0728	peptidoglycan biosynthetic process
ACRY_RS07550	COG0180	Tryptophanyl-tRNA synthetase
ACRY_RS07570	COG0596	Alpha beta hydrolase
ACRY_RS07615	COG1960	acyl-CoA dehydrogenase activity
ACRY_RS07625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACRY_RS07640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACRY_RS07645	COG0506	proline dehydrogenase activity
ACRY_RS07645	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACRY_RS07645	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACRY_RS07680	COG0129	dihydroxy-acid dehydratase activity
ACRY_RS07685	COG0477	Major facilitator Superfamily
ACRY_RS07700	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS07715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACRY_RS07720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACRY_RS07725	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACRY_RS07740	COG1573	uracil-dna glycosylase
ACRY_RS07765	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS07770	COG1129	ABC transporter
ACRY_RS07780	COG2186	Transcriptional regulator
ACRY_RS07785	COG1850	ribulose-bisphosphate carboxylase activity
ACRY_RS07795	COG0287	Prephenate dehydrogenase
ACRY_RS07805	COG1129	ABC transporter
ACRY_RS07815	COG0431	NADPH-dependent FMN reductase
ACRY_RS07830	COG0668	transmembrane transport
ACRY_RS07855	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACRY_RS07890	COG2072	flavoprotein involved in K transport
ACRY_RS07920	COG1845	cytochrome c oxidase, subunit III
ACRY_RS07925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACRY_RS07930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACRY_RS07945	COG0583	DNA-binding transcription factor activity
ACRY_RS07950	COG2226	methyltransferase
ACRY_RS07955	COG3300	MHYT domain
ACRY_RS07955	COG5001	Diguanylate cyclase
ACRY_RS07960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACRY_RS07970	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACRY_RS07975	COG0517	IMP dehydrogenase activity
ACRY_RS07975	COG0516	GMP reductase activity
ACRY_RS07980	COG1007	ATP synthesis coupled electron transport
ACRY_RS07995	COG0713	ATP synthesis coupled electron transport
ACRY_RS08005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS08010	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACRY_RS08025	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACRY_RS08030	COG0649	NAD binding
ACRY_RS08030	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS08035	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS08040	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRY_RS08045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACRY_RS08055	COG0673	inositol 2-dehydrogenase activity
ACRY_RS08060	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACRY_RS08065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACRY_RS08085	COG0789	Transcriptional regulator
ACRY_RS08100	COG2132	Multicopper oxidase
ACRY_RS08105	COG2755	lipolytic protein G-D-S-L family
ACRY_RS08105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACRY_RS08115	COG0765	amino acid transport
ACRY_RS08125	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS08130	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS08135	COG1129	ABC transporter
ACRY_RS08145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACRY_RS08170	COG0402	S-adenosylhomocysteine deaminase activity
ACRY_RS08180	COG3195	allantoin biosynthetic process
ACRY_RS08180	COG3648	Uricase
ACRY_RS08190	COG2351	hydroxyisourate hydrolase activity
ACRY_RS08210	COG0583	DNA-binding transcription factor activity
ACRY_RS08215	COG3960	tartronate-semialdehyde synthase activity
ACRY_RS08220	COG3622	Belongs to the hyi family
ACRY_RS08225	COG2084	Dehydrogenase
ACRY_RS08240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACRY_RS08265	COG0582	viral genome integration into host DNA
ACRY_RS08300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACRY_RS08305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACRY_RS08320	COG1862	Preprotein translocase
ACRY_RS08340	COG0601	transmembrane transport
ACRY_RS08345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACRY_RS08355	COG0811	peptide transport
ACRY_RS08365	COG4974	Belongs to the 'phage' integrase family
ACRY_RS08375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACRY_RS08375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACRY_RS08390	COG0318	PFAM AMP-dependent synthetase and ligase
ACRY_RS08405	COG0142	geranyltranstransferase activity
ACRY_RS08410	COG1722	exodeoxyribonuclease VII activity
ACRY_RS08415	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACRY_RS08425	COG1940	carbohydrate kinase activity
ACRY_RS08435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACRY_RS08455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACRY_RS08460	COG1381	Involved in DNA repair and RecF pathway recombination
ACRY_RS08470	COG1473	amidohydrolase
ACRY_RS08485	COG1088	dTDP-glucose 4,6-dehydratase activity
ACRY_RS08490	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ACRY_RS08495	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ACRY_RS08500	COG1091	dTDP-4-dehydrorhamnose reductase activity
ACRY_RS08525	COG0126	phosphoglycerate kinase activity
ACRY_RS08530	COG0312	modulator of DNA gyrase
ACRY_RS08535	COG1612	heme a metabolic process
ACRY_RS08540	COG1612	heme a metabolic process
ACRY_RS08545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACRY_RS08555	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACRY_RS08570	COG0315	cyclic pyranopterin monophosphate synthase activity
ACRY_RS08575	COG0134	indole-3-glycerol-phosphate synthase activity
ACRY_RS08580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACRY_RS08580	COG0512	Glutamine amidotransferase of anthranilate synthase
ACRY_RS08585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACRY_RS08595	COG0149	triose-phosphate isomerase activity
ACRY_RS08600	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACRY_RS08605	COG0504	CTP synthase activity
ACRY_RS08610	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACRY_RS08695	COG0318	PFAM AMP-dependent synthetase and ligase
ACRY_RS08700	COG0183	Belongs to the thiolase family
ACRY_RS08710	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS08715	COG1960	acyl-CoA dehydrogenase activity
ACRY_RS08725	COG3239	Fatty acid desaturase
ACRY_RS08760	COG2271	Major facilitator Superfamily
ACRY_RS08765	COG0473	3-isopropylmalate dehydrogenase activity
ACRY_RS08770	COG3387	PFAM Glycoside hydrolase 15-related
ACRY_RS08775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACRY_RS08780	COG0363	glucosamine-6-phosphate deaminase activity
ACRY_RS08790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACRY_RS08795	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACRY_RS08800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACRY_RS08805	COG0481	GTPase activity
ACRY_RS08820	COG0582	viral genome integration into host DNA
ACRY_RS08840	COG2259	Doxx family
ACRY_RS08845	COG0583	DNA-binding transcription factor activity
ACRY_RS08900	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ACRY_RS08900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACRY_RS08905	COG1494	fructose-1,6-bisphosphatase
ACRY_RS08915	COG0436	Aminotransferase
ACRY_RS08925	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACRY_RS08930	COG0438	transferase activity, transferring glycosyl groups
ACRY_RS08940	COG0523	cobalamin synthesis protein
ACRY_RS08950	COG0656	L-ascorbic acid biosynthetic process
ACRY_RS08955	COG1217	gtp-binding protein TYPA
ACRY_RS08965	COG2223	nitrite transmembrane transporter activity
ACRY_RS08970	COG0488	(ABC) transporter
ACRY_RS08975	COG0105	UTP biosynthetic process
ACRY_RS08995	COG1846	Transcriptional regulator
ACRY_RS09010	COG0175	sulfate reduction
ACRY_RS09020	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACRY_RS09045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACRY_RS09050	COG0400	carboxylic ester hydrolase activity
ACRY_RS09060	COG0133	tryptophan synthase activity
ACRY_RS09065	COG0159	tryptophan synthase activity
ACRY_RS09075	COG1570	exodeoxyribonuclease VII activity
ACRY_RS09105	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACRY_RS09105	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACRY_RS09115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACRY_RS09120	COG0343	queuine tRNA-ribosyltransferase activity
ACRY_RS09125	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACRY_RS09130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACRY_RS09135	COG1970	mechanosensitive ion channel activity
ACRY_RS09150	COG1380	Effector of murein hydrolase LrgA
ACRY_RS09155	COG0583	DNA-binding transcription factor activity
ACRY_RS09160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACRY_RS09165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACRY_RS09175	COG3754	Rhamnan synthesis protein F
ACRY_RS09185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACRY_RS09195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACRY_RS09230	COG1132	(ABC) transporter
ACRY_RS09265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACRY_RS09300	COG0459	protein refolding
ACRY_RS09320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACRY_RS09325	COG3350	monooxygenase activity
ACRY_RS09360	COG3118	belongs to the thioredoxin family
ACRY_RS09365	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACRY_RS09370	COG0640	Transcriptional regulator
ACRY_RS09395	COG0651	ATP synthesis coupled electron transport
ACRY_RS09400	COG0650	Formate hydrogenlyase subunit 4
ACRY_RS09410	COG0651	ATP synthesis coupled electron transport
ACRY_RS09420	COG3260	NADH ubiquinone oxidoreductase 20
ACRY_RS09435	COG0215	cysteine-tRNA ligase activity
ACRY_RS09440	COG1914	H( )-stimulated, divalent metal cation uptake system
ACRY_RS09445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACRY_RS09450	COG0154	amidase activity
ACRY_RS09460	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ACRY_RS09465	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACRY_RS09475	COG0477	Major facilitator Superfamily
ACRY_RS09480	COG0131	Imidazoleglycerol-phosphate dehydratase
ACRY_RS09485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACRY_RS09495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACRY_RS09500	COG0107	imidazoleglycerol-phosphate synthase activity
ACRY_RS09505	COG0140	phosphoribosyl-ATP diphosphatase activity
ACRY_RS09515	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACRY_RS09525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACRY_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS09555	COG2902	Dehydrogenase
ACRY_RS09570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACRY_RS09580	COG0142	geranyltranstransferase activity
ACRY_RS09590	COG2264	protein methyltransferase activity
ACRY_RS09600	COG0427	acetyl-CoA hydrolase
ACRY_RS09610	COG4176	ABC-type proline glycine betaine transport system permease component
ACRY_RS09615	COG1116	anion transmembrane transporter activity
ACRY_RS09620	COG0114	fumarate hydratase activity
ACRY_RS09635	COG3384	dioxygenase
ACRY_RS09655	COG0194	GDP metabolic process
ACRY_RS09660	COG1561	YicC-like family, N-terminal region
ACRY_RS09665	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ACRY_RS09670	COG1024	Enoyl-CoA hydratase
ACRY_RS09675	COG0492	ferredoxin-NADP+ reductase activity
ACRY_RS09680	COG0802	atpase or kinase
ACRY_RS09690	COG1074	ATP-dependent DNA helicase activity
ACRY_RS09700	COG1607	acyl-coa hydrolase
ACRY_RS09705	COG2814	Major facilitator Superfamily
ACRY_RS09710	COG0667	Aldo Keto reductase
ACRY_RS09715	COG0811	peptide transport
ACRY_RS09720	COG0848	biopolymer transport protein
ACRY_RS09730	COG1692	metallophosphoesterase
ACRY_RS09735	COG3038	cytochrome b561
ACRY_RS09750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACRY_RS09755	COG4974	Belongs to the 'phage' integrase family
ACRY_RS09770	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACRY_RS09780	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACRY_RS09785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACRY_RS09800	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACRY_RS09805	COG1187	pseudouridine synthase activity
ACRY_RS09810	COG0742	ribosomal rna small subunit methyltransferase
ACRY_RS09820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACRY_RS09830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACRY_RS09835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACRY_RS09850	COG0668	transmembrane transport
ACRY_RS09870	COG2814	Major facilitator Superfamily
ACRY_RS09875	COG0024	Methionine aminopeptidase
ACRY_RS09880	COG2003	Belongs to the UPF0758 family
ACRY_RS09895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACRY_RS09915	COG3800	Transcriptional regulator
ACRY_RS09915	COG1396	sequence-specific DNA binding
ACRY_RS09920	COG2224	Isocitrate lyase
ACRY_RS09935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACRY_RS09935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACRY_RS09950	COG0717	Belongs to the dCTP deaminase family
ACRY_RS09955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACRY_RS09960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACRY_RS09965	COG0359	binds to the 23S rRNA
ACRY_RS09970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACRY_RS09975	COG0360	Binds together with S18 to 16S ribosomal RNA
ACRY_RS09985	COG4770	biotin carboxylase activity
ACRY_RS09995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACRY_RS10040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACRY_RS10050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACRY_RS10055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACRY_RS10070	COG2171	N-acyltransferase activity
ACRY_RS10075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACRY_RS10085	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACRY_RS10095	COG5002	protein histidine kinase activity
ACRY_RS10100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACRY_RS10105	COG2096	Adenosyltransferase
ACRY_RS10115	COG0300	oxidoreductase activity
ACRY_RS10125	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACRY_RS10130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACRY_RS10150	COG1058	Belongs to the CinA family
ACRY_RS10150	COG1546	Belongs to the CinA family
ACRY_RS10155	COG0494	nUDIX hydrolase
ACRY_RS10160	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACRY_RS10165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACRY_RS10170	COG0799	negative regulation of ribosome biogenesis
ACRY_RS10175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACRY_RS10185	COG5001	Diguanylate cyclase
ACRY_RS10190	COG3300	MHYT domain
ACRY_RS10190	COG5001	Diguanylate cyclase
ACRY_RS10205	COG1960	acyl-CoA dehydrogenase activity
ACRY_RS10215	COG5285	phytanoyl-CoA dioxygenase
ACRY_RS10225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACRY_RS10260	COG0275	rRNA processing
ACRY_RS10295	COG1960	acyl-CoA dehydrogenase activity
ACRY_RS10310	COG0183	Belongs to the thiolase family
ACRY_RS10320	COG0667	Aldo Keto reductase
ACRY_RS10335	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ACRY_RS10340	COG1140	nitrate reductase beta subunit
ACRY_RS10345	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ACRY_RS10350	COG2181	nitrate reductase activity
ACRY_RS10370	COG0840	transmembrane signaling receptor activity
ACRY_RS10380	COG1063	alcohol dehydrogenase
ACRY_RS10385	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS10390	COG2084	Dehydrogenase
ACRY_RS10395	COG1129	ABC transporter
ACRY_RS10415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACRY_RS10420	COG0477	Major facilitator Superfamily
ACRY_RS10425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACRY_RS10440	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS10450	COG2199	diguanylate cyclase activity
ACRY_RS10455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACRY_RS10475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACRY_RS10480	COG1793	dna ligase
ACRY_RS10490	COG1201	RNA secondary structure unwinding
ACRY_RS10500	COG0415	Belongs to the DNA photolyase family
ACRY_RS10515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACRY_RS10520	COG2211	Major facilitator Superfamily
ACRY_RS10530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACRY_RS10535	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACRY_RS10550	COG0045	succinate-CoA ligase (ADP-forming) activity
ACRY_RS10555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACRY_RS10560	COG0405	Gamma-glutamyltransferase
ACRY_RS10565	COG0436	Aminotransferase
ACRY_RS10570	COG0517	IMP dehydrogenase activity
ACRY_RS10570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACRY_RS10570	COG0617	tRNA 3'-terminal CCA addition
ACRY_RS10575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACRY_RS10590	COG1294	oxidase, subunit
ACRY_RS10595	COG1271	oxidase subunit
ACRY_RS10600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACRY_RS10605	COG4988	ABC transporter
ACRY_RS10625	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS10645	COG0484	heat shock protein binding
ACRY_RS10650	COG0443	Heat shock 70 kDa protein
ACRY_RS10655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACRY_RS10665	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS10680	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACRY_RS10685	COG0328	RNA-DNA hybrid ribonuclease activity
ACRY_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS10695	COG3842	ATPase activity
ACRY_RS10705	COG1175	transmembrane transport
ACRY_RS10715	COG1063	alcohol dehydrogenase
ACRY_RS10720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACRY_RS10735	COG1420	regulation of RNA biosynthetic process
ACRY_RS10740	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACRY_RS10745	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACRY_RS10775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACRY_RS10775	COG0517	IMP dehydrogenase activity
ACRY_RS10790	COG1137	ATPase activity
ACRY_RS10795	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACRY_RS10800	COG0193	aminoacyl-tRNA hydrolase activity
ACRY_RS10805	COG0012	GTP binding
ACRY_RS10815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACRY_RS10820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACRY_RS10825	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACRY_RS10830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACRY_RS10835	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACRY_RS10850	COG1657	PFAM Prenyltransferase squalene oxidase
ACRY_RS10860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACRY_RS10865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACRY_RS10880	COG2301	Belongs to the HpcH HpaI aldolase family
ACRY_RS10885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ACRY_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS10900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACRY_RS10905	COG0052	Belongs to the universal ribosomal protein uS2 family
ACRY_RS10910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACRY_RS10930	COG0646	methionine synthase
ACRY_RS10930	COG1410	methionine synthase
ACRY_RS10935	COG0697	spore germination
ACRY_RS10960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACRY_RS10965	COG0483	inositol monophosphate 1-phosphatase activity
ACRY_RS11010	COG1024	Enoyl-CoA hydratase
ACRY_RS11020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACRY_RS11030	COG0746	molybdenum cofactor guanylyltransferase activity
ACRY_RS11035	COG2095	MarC family integral membrane protein
ACRY_RS11040	COG0776	regulation of translation
ACRY_RS11050	COG0284	orotidine-5'-phosphate decarboxylase activity
ACRY_RS11055	COG0135	phosphoribosylanthranilate isomerase activity
ACRY_RS11060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACRY_RS11065	COG2226	methyltransferase
ACRY_RS11070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACRY_RS11075	COG0756	dUTP diphosphatase activity
ACRY_RS11080	COG4221	oxidoreductase activity
ACRY_RS11085	COG3046	protein related to deoxyribodipyrimidine photolyase
ACRY_RS11110	COG1902	pentaerythritol trinitrate reductase activity
ACRY_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS11135	COG2010	Cytochrome c
ACRY_RS11155	COG1012	belongs to the aldehyde dehydrogenase family
ACRY_RS11160	COG3284	Transcriptional regulator
ACRY_RS11170	COG1228	amidohydrolase
ACRY_RS11175	COG2986	histidine ammonia-lyase
ACRY_RS11185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACRY_RS11190	COG2188	Transcriptional regulator
ACRY_RS11200	COG0393	Putative heavy-metal-binding
ACRY_RS11210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACRY_RS11215	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACRY_RS11220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACRY_RS11225	COG1051	belongs to the nudix hydrolase family
ACRY_RS11230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACRY_RS11235	COG3956	TIGRFAM MazG family protein
ACRY_RS11240	COG0483	inositol monophosphate 1-phosphatase activity
ACRY_RS11245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACRY_RS11250	COG1923	regulation of RNA biosynthetic process
ACRY_RS11260	COG0482	sulfurtransferase activity
ACRY_RS11275	COG1045	serine acetyltransferase
ACRY_RS11280	COG2945	thiolester hydrolase activity
ACRY_RS11285	COG1349	DNA-binding transcription factor activity
ACRY_RS11310	COG0778	Nitroreductase
ACRY_RS11315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACRY_RS11325	COG2226	methyltransferase
ACRY_RS11330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACRY_RS11345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACRY_RS11360	COG0525	valine-tRNA ligase activity
ACRY_RS11370	COG0312	modulator of DNA gyrase
ACRY_RS11375	COG0612	Peptidase, M16
ACRY_RS11385	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACRY_RS11395	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ACRY_RS11420	COG1131	(ABC) transporter
ACRY_RS11425	COG0842	Transport permease protein
ACRY_RS11430	COG0842	Transport permease protein
ACRY_RS11435	COG1151	hydroxylamine reductase activity
ACRY_RS11440	COG0543	2 iron, 2 sulfur cluster binding
ACRY_RS11440	COG0633	Ferredoxin
ACRY_RS11445	COG1959	2 iron, 2 sulfur cluster binding
ACRY_RS11460	COG0438	transferase activity, transferring glycosyl groups
ACRY_RS11495	COG1857	crispr-associated protein
ACRY_RS11510	COG1203	CRISPR-associated helicase, Cas3
ACRY_RS11520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACRY_RS11575	COG0542	response to heat
ACRY_RS11585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACRY_RS11590	COG1763	Mo-molybdopterin cofactor biosynthetic process
ACRY_RS11605	COG0314	molybdopterin synthase activity
ACRY_RS11610	COG0745	RESPONSE REGULATOR receiver
ACRY_RS11620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACRY_RS11625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACRY_RS11640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACRY_RS11645	COG3394	polysaccharide catabolic process
ACRY_RS11680	COG0513	Belongs to the DEAD box helicase family
ACRY_RS11685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACRY_RS11700	COG3485	protocatechuate 3,4-dioxygenase
ACRY_RS11705	COG3485	protocatechuate 3,4-dioxygenase
ACRY_RS11715	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACRY_RS11720	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS11730	COG1129	ABC transporter
ACRY_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS11740	COG3618	amidohydrolase
ACRY_RS11745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACRY_RS11750	COG1312	Catalyzes the dehydration of D-mannonate
ACRY_RS11770	COG2721	sulfolactate sulfo-lyase activity
ACRY_RS11785	COG0559	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS11795	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACRY_RS11800	COG0156	8-amino-7-oxononanoate synthase activity
ACRY_RS11805	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACRY_RS11810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACRY_RS11830	COG3038	cytochrome b561
ACRY_RS11850	COG2264	protein methyltransferase activity
ACRY_RS11855	COG2009	succinate dehydrogenase
ACRY_RS11865	COG1053	succinate dehydrogenase
ACRY_RS11880	COG2205	protein histidine kinase activity
ACRY_RS11885	COG0745	RESPONSE REGULATOR receiver
ACRY_RS11895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACRY_RS11905	COG1473	amidohydrolase
ACRY_RS11915	COG1846	Transcriptional regulator
ACRY_RS11920	COG1566	PFAM secretion protein HlyD family protein
ACRY_RS11925	COG2814	Major facilitator Superfamily
ACRY_RS11930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACRY_RS11970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACRY_RS11975	COG1360	Flagellar Motor Protein
ACRY_RS11990	COG0463	Glycosyl transferase, family 2
ACRY_RS12005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACRY_RS12010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACRY_RS12015	COG0741	lytic transglycosylase activity
ACRY_RS12020	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACRY_RS12025	COG1058	Belongs to the CinA family
ACRY_RS12025	COG1546	Belongs to the CinA family
ACRY_RS12080	COG0203	ribosomal protein L17
ACRY_RS12085	COG0202	RNA polymerase activity
ACRY_RS12090	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACRY_RS12095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACRY_RS12100	COG0563	adenylate kinase activity
ACRY_RS12110	COG0200	Binds to the 23S rRNA
ACRY_RS12115	COG1841	ribosomal large subunit assembly
ACRY_RS12120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACRY_RS12125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACRY_RS12130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACRY_RS12135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACRY_RS12140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACRY_RS12145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACRY_RS12150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACRY_RS12155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACRY_RS12160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACRY_RS12165	COG0255	Belongs to the universal ribosomal protein uL29 family
ACRY_RS12170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACRY_RS12175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACRY_RS12180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACRY_RS12185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACRY_RS12190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACRY_RS12195	COG0089	rRNA binding
ACRY_RS12200	COG0088	Forms part of the polypeptide exit tunnel
ACRY_RS12205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACRY_RS12210	COG0051	transcription antitermination factor activity, RNA binding
ACRY_RS12215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACRY_RS12220	COG0049	tRNA binding
ACRY_RS12225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACRY_RS12230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACRY_RS12235	COG0085	RNA polymerase activity
ACRY_RS12240	COG0222	ribosome binding
ACRY_RS12245	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACRY_RS12250	COG0081	regulation of translation
ACRY_RS12255	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACRY_RS12260	COG3047	cAMP biosynthetic process
ACRY_RS12265	COG0667	Aldo Keto reductase
ACRY_RS12270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACRY_RS12275	COG0647	UMP catabolic process
ACRY_RS12290	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACRY_RS12295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACRY_RS12330	COG4214	carbohydrate transport
ACRY_RS12340	COG4213	ABC transporter substrate-binding protein
ACRY_RS12350	COG5265	(ABC) transporter
ACRY_RS12385	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACRY_RS12415	COG0776	regulation of translation
ACRY_RS12430	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ACRY_RS12450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACRY_RS12455	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACRY_RS12475	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACRY_RS12480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACRY_RS12490	COG2816	NAD+ diphosphatase activity
ACRY_RS12495	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACRY_RS12520	COG0714	Associated with various cellular activities
ACRY_RS12530	COG0494	nUDIX hydrolase
ACRY_RS12535	COG0617	tRNA 3'-terminal CCA addition
ACRY_RS12540	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACRY_RS12545	COG0248	Ppx GppA phosphatase
ACRY_RS12560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACRY_RS12565	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ACRY_RS12600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACRY_RS12625	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACRY_RS12635	COG0473	3-isopropylmalate dehydrogenase activity
ACRY_RS12645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACRY_RS12645	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACRY_RS12670	COG2204	response regulator
ACRY_RS12680	COG0629	single-stranded DNA binding
ACRY_RS12685	COG1294	oxidase, subunit
ACRY_RS12690	COG1271	oxidase subunit
ACRY_RS12700	COG3781	membrane
ACRY_RS12710	COG0243	molybdopterin cofactor binding
ACRY_RS12740	COG0495	leucyl-tRNA aminoacylation
ACRY_RS12765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACRY_RS12770	COG2733	membrane
ACRY_RS12785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACRY_RS12805	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACRY_RS12815	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACRY_RS12830	COG2271	Major facilitator Superfamily
ACRY_RS12835	COG4638	Rieske (2fe-2S)
ACRY_RS12850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACRY_RS12855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACRY_RS12870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACRY_RS12875	COG0601	transmembrane transport
ACRY_RS12900	COG1280	lysine exporter protein (LysE YggA)
ACRY_RS12910	COG3008	intermembrane lipid transfer
ACRY_RS12980	COG0515	serine threonine protein kinase
ACRY_RS12995	COG0514	ATP-dependent DNA helicase (RecQ)
ACRY_RS13010	COG0308	aminopeptidase N
ACRY_RS13030	COG3328	transposase activity
ACRY_RS13035	COG0531	amino acid
ACRY_RS13040	COG0259	pyridoxamine-phosphate oxidase activity
ACRY_RS13045	COG0625	glutathione transferase activity
ACRY_RS13060	COG3321	synthase
ACRY_RS13060	COG0604	alcohol dehydrogenase
ACRY_RS13060	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS13070	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACRY_RS13075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACRY_RS13085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACRY_RS13085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACRY_RS13095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACRY_RS13095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACRY_RS13100	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACRY_RS13105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACRY_RS13110	COG0698	ribose 5-phosphate isomerase
ACRY_RS13120	COG2835	tetraacyldisaccharide 4'-kinase activity
ACRY_RS13140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACRY_RS13145	COG1684	flagellar biosynthetic protein fliR
ACRY_RS13150	COG1987	bacterial-type flagellum assembly
ACRY_RS13155	COG1677	Flagellar hook-basal body complex protein FliE
ACRY_RS13160	COG1558	bacterial-type flagellum-dependent cell motility
ACRY_RS13175	COG1338	Plays a role in the flagellum-specific transport system
ACRY_RS13180	COG5000	phosphorelay sensor kinase activity
ACRY_RS13190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACRY_RS13195	COG0594	ribonuclease P activity
ACRY_RS13200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACRY_RS13205	COG0706	membrane insertase activity
ACRY_RS13210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACRY_RS13215	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACRY_RS13220	COG0840	transmembrane signaling receptor activity
ACRY_RS13225	COG1253	flavin adenine dinucleotide binding
ACRY_RS13235	COG0473	3-isopropylmalate dehydrogenase activity
ACRY_RS13240	COG0066	3-isopropylmalate dehydratase activity
ACRY_RS13245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACRY_RS13250	COG0335	large ribosomal subunit rRNA binding
ACRY_RS13255	COG0336	Belongs to the RNA methyltransferase TrmD family
ACRY_RS13260	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACRY_RS13265	COG0228	four-way junction DNA binding
ACRY_RS13270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACRY_RS13290	COG0740	serine-type endopeptidase activity
ACRY_RS13305	COG1802	Transcriptional regulator
ACRY_RS13325	COG0109	protoheme IX farnesyltransferase activity
ACRY_RS13330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACRY_RS13335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACRY_RS13335	COG1565	acr, cog1565
ACRY_RS13360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACRY_RS13385	COG0477	Major facilitator Superfamily
ACRY_RS13420	COG0574	Belongs to the PEP-utilizing enzyme family
ACRY_RS13420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACRY_RS13425	COG0751	glycine-tRNA ligase activity
ACRY_RS13430	COG0752	glycyl-tRNA synthetase alpha subunit
ACRY_RS13440	COG1960	acyl-CoA dehydrogenase activity
ACRY_RS13445	COG0825	malonyl-CoA metabolic process
ACRY_RS13460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACRY_RS13475	COG0859	PFAM glycosyl transferase family 9
ACRY_RS13480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACRY_RS13495	COG1414	Transcriptional regulator
ACRY_RS13535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACRY_RS13570	COG1129	ABC transporter
ACRY_RS13575	COG1879	ABC-type sugar transport system periplasmic component
ACRY_RS13585	COG1695	Transcriptional regulator
ACRY_RS13620	COG1473	amidohydrolase
ACRY_RS13630	COG0583	DNA-binding transcription factor activity
ACRY_RS13635	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS13645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACRY_RS13660	COG1129	ABC transporter
ACRY_RS13665	COG1879	ABC-type sugar transport system periplasmic component
ACRY_RS13670	COG1414	Transcriptional regulator
ACRY_RS13685	COG1802	Transcriptional regulator
ACRY_RS13690	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACRY_RS13695	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACRY_RS13700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACRY_RS13705	COG0653	protein targeting
ACRY_RS13720	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACRY_RS13725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACRY_RS13735	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ACRY_RS13740	COG0730	response to heat
ACRY_RS13750	COG0183	Belongs to the thiolase family
ACRY_RS13765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACRY_RS13775	COG0792	nuclease activity
ACRY_RS13785	COG2897	thiosulfate sulfurtransferase activity
ACRY_RS13795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACRY_RS13800	COG0316	Belongs to the HesB IscA family
ACRY_RS13805	COG2151	metal-sulfur cluster biosynthetic enzyme
ACRY_RS13815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACRY_RS13820	COG0719	Fe-S assembly protein
ACRY_RS13825	COG0396	ATPase activity
ACRY_RS13830	COG0719	Fe-S assembly protein
ACRY_RS13845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACRY_RS13850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACRY_RS13855	COG1719	4-vinyl reductase, 4VR
ACRY_RS13880	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ACRY_RS13890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACRY_RS13895	COG0281	malic enzyme
ACRY_RS13895	COG0280	phosphate acetyltransferase
ACRY_RS13905	COG0321	lipoyl(octanoyl) transferase activity
ACRY_RS13975	COG1484	DNA-dependent DNA replication
ACRY_RS13980	COG4584	PFAM Integrase catalytic
ACRY_RS14020	COG0582	viral genome integration into host DNA
ACRY_RS14025	COG0582	viral genome integration into host DNA
ACRY_RS14030	COG3718	enzyme involved in inositol metabolism
ACRY_RS14035	COG3962	Belongs to the TPP enzyme family
ACRY_RS14045	COG1129	ABC transporter
ACRY_RS14065	COG0673	inositol 2-dehydrogenase activity
ACRY_RS14070	COG1082	Xylose isomerase domain protein TIM barrel
ACRY_RS14080	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS14105	COG0673	inositol 2-dehydrogenase activity
ACRY_RS14110	COG0673	inositol 2-dehydrogenase activity
ACRY_RS14115	COG3002	Belongs to the UPF0753 family
ACRY_RS14120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACRY_RS14135	COG1595	DNA-templated transcription, initiation
ACRY_RS14180	COG0415	Belongs to the DNA photolyase family
ACRY_RS14205	COG4974	Belongs to the 'phage' integrase family
ACRY_RS14210	COG0517	IMP dehydrogenase activity
ACRY_RS14270	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACRY_RS14275	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS14295	COG0735	belongs to the Fur family
ACRY_RS14300	COG0318	PFAM AMP-dependent synthetase and ligase
ACRY_RS14310	COG0604	alcohol dehydrogenase
ACRY_RS14315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACRY_RS14320	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ACRY_RS14325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACRY_RS14335	COG1121	(ABC) transporter
ACRY_RS14375	COG1509	lysine 2,3-aminomutase activity
ACRY_RS14385	COG0511	ligase activity, forming carbon-carbon bonds
ACRY_RS14390	COG0439	Biotin carboxylase
ACRY_RS14400	COG3300	MHYT domain
ACRY_RS14400	COG5001	Diguanylate cyclase
ACRY_RS14405	COG0243	molybdopterin cofactor binding
ACRY_RS14410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACRY_RS14415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACRY_RS14430	COG0840	transmembrane signaling receptor activity
ACRY_RS14435	COG0625	glutathione transferase activity
ACRY_RS14440	COG1012	belongs to the aldehyde dehydrogenase family
ACRY_RS14445	COG1012	belongs to the aldehyde dehydrogenase family
ACRY_RS14475	COG3706	GGDEF domain
ACRY_RS14485	COG0183	Belongs to the thiolase family
ACRY_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS14495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACRY_RS14505	COG2226	methyltransferase
ACRY_RS14525	COG0357	Ribosomal RNA small subunit methyltransferase G
ACRY_RS14530	COG0445	tRNA wobble uridine modification
ACRY_RS14535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACRY_RS14545	COG1331	Highly conserved protein containing a thioredoxin domain
ACRY_RS14550	COG0489	protein tyrosine kinase activity
ACRY_RS14565	COG2081	HI0933 family
ACRY_RS14575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACRY_RS14580	COG2076	Multidrug Resistance protein
ACRY_RS14630	COG0582	viral genome integration into host DNA
ACRY_RS14640	COG3395	kinase activity
ACRY_RS14645	COG3622	Belongs to the hyi family
ACRY_RS14650	COG2084	Dehydrogenase
ACRY_RS14655	COG1609	Transcriptional regulator
ACRY_RS14660	COG2084	Dehydrogenase
ACRY_RS14665	COG0235	Class ii aldolase
ACRY_RS14680	COG0477	Major facilitator Superfamily
ACRY_RS14690	COG3180	Ammonia monooxygenase
ACRY_RS14695	COG0583	DNA-binding transcription factor activity
ACRY_RS14700	COG0492	ferredoxin-NADP+ reductase activity
ACRY_RS14705	COG1522	sequence-specific DNA binding
ACRY_RS14715	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACRY_RS14725	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACRY_RS14730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACRY_RS14740	COG3494	Protein of unknown function (DUF1009)
ACRY_RS14745	COG0346	lactoylglutathione lyase activity
ACRY_RS14750	COG0457	Tetratricopeptide repeat
ACRY_RS14785	COG0488	(ABC) transporter
ACRY_RS14795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACRY_RS14800	COG0318	PFAM AMP-dependent synthetase and ligase
ACRY_RS14810	COG2608	mercury ion transmembrane transporter activity
ACRY_RS14815	COG2217	Heavy metal translocating P-type atpase
ACRY_RS14820	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS14830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACRY_RS14835	COG0129	dihydroxy-acid dehydratase activity
ACRY_RS14845	COG1981	membrane
ACRY_RS14860	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACRY_RS14865	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ACRY_RS14870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACRY_RS14890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACRY_RS14905	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ACRY_RS14935	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACRY_RS14940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACRY_RS14945	COG0586	Pfam SNARE associated Golgi protein
ACRY_RS14960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACRY_RS14975	COG0552	protein localization to endoplasmic reticulum
ACRY_RS14980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACRY_RS14985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACRY_RS14995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACRY_RS15005	COG2814	Major facilitator Superfamily
ACRY_RS15010	COG0459	protein refolding
ACRY_RS15015	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACRY_RS15020	COG5425	PFAM Usg family protein
ACRY_RS15170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACRY_RS15185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACRY_RS15190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACRY_RS15200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACRY_RS15205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACRY_RS15210	COG0248	Ppx GppA phosphatase
ACRY_RS15225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACRY_RS15240	COG0247	lactate metabolic process
ACRY_RS15245	COG0277	FAD linked oxidase domain protein
ACRY_RS15250	COG0277	FAD linked oxidase domain protein
ACRY_RS15255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACRY_RS15265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACRY_RS15270	COG0528	UMP kinase activity
ACRY_RS15275	COG0233	cytoplasmic translational termination
ACRY_RS15280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACRY_RS15290	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACRY_RS15295	COG0750	zinc metalloprotease
ACRY_RS15300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACRY_RS15310	COG0586	Pfam SNARE associated Golgi protein
ACRY_RS15325	COG1070	Carbohydrate kinase
ACRY_RS15335	COG1653	transport
ACRY_RS15345	COG3833	ABC-type maltose transport systems, permease component
ACRY_RS15365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACRY_RS15370	COG0235	Class ii aldolase
ACRY_RS15385	COG2860	membrane
ACRY_RS15400	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ACRY_RS15405	COG2030	dehydratase
ACRY_RS15410	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS15450	COG0840	transmembrane signaling receptor activity
ACRY_RS15455	COG3386	PFAM SMP-30 Gluconolaconase
ACRY_RS15460	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS15465	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS15470	COG1129	ABC transporter
ACRY_RS15480	COG3386	PFAM SMP-30 Gluconolaconase
ACRY_RS15485	COG0800	Aldolase
ACRY_RS15490	COG3734	2-keto-3-deoxy-galactonokinase
ACRY_RS15505	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS15535	COG3396	Phenylacetate-CoA oxygenase
ACRY_RS15540	COG3460	Phenylacetate-CoA oxygenase
ACRY_RS15545	COG3396	Phenylacetate-CoA oxygenase
ACRY_RS15550	COG2151	metal-sulfur cluster biosynthetic enzyme
ACRY_RS15555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACRY_RS15575	COG2376	Dihydroxyacetone kinase
ACRY_RS15580	COG1461	Dihydroxyacetone kinase
ACRY_RS15595	COG0606	chelatase, subunit chli
ACRY_RS15600	COG2003	Belongs to the UPF0758 family
ACRY_RS15605	COG0251	oxidation-reduction process
ACRY_RS15615	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACRY_RS15620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACRY_RS15640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACRY_RS15645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACRY_RS15650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACRY_RS15655	COG0071	Belongs to the small heat shock protein (HSP20) family
ACRY_RS15660	COG0254	rRNA binding
ACRY_RS15670	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACRY_RS15690	COG0513	Belongs to the DEAD box helicase family
ACRY_RS15695	COG3284	Transcriptional regulator
ACRY_RS15715	COG3302	dmso reductase anchor subunit
ACRY_RS15720	COG0437	4 iron, 4 sulfur cluster binding
ACRY_RS15725	COG0243	molybdopterin cofactor binding
ACRY_RS15730	COG0076	glutamate decarboxylase activity
ACRY_RS15745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACRY_RS15765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACRY_RS15765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACRY_RS15780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACRY_RS15795	COG0667	Aldo Keto reductase
ACRY_RS15800	COG0302	gtp cyclohydrolase
ACRY_RS15805	COG2967	ApaG domain
ACRY_RS15815	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACRY_RS15820	COG0047	phosphoribosylformylglycinamidine synthase activity
ACRY_RS15825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACRY_RS15830	COG0271	Belongs to the BolA IbaG family
ACRY_RS15835	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACRY_RS15845	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ACRY_RS15855	COG2095	MarC family integral membrane protein
ACRY_RS15865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACRY_RS15870	COG2223	nitrite transmembrane transporter activity
ACRY_RS15875	COG1321	iron dependent repressor
ACRY_RS15885	COG0628	permease
ACRY_RS15890	COG1254	Belongs to the acylphosphatase family
ACRY_RS15920	COG1183	phosphatidylcholine synthase activity
ACRY_RS15925	COG0688	phosphatidylethanolamine metabolic process
ACRY_RS15940	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACRY_RS15945	COG1530	ribonuclease E activity
ACRY_RS15950	COG0424	maF-like protein
ACRY_RS15955	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACRY_RS15960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACRY_RS15970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACRY_RS15975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACRY_RS15980	COG2084	Dehydrogenase
ACRY_RS16000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACRY_RS16010	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACRY_RS16025	COG0840	transmembrane signaling receptor activity
ACRY_RS16035	COG0745	RESPONSE REGULATOR receiver
ACRY_RS16040	COG0643	Histidine kinase
ACRY_RS16040	COG2198	Histidine kinase
ACRY_RS16045	COG0835	chemotaxis
ACRY_RS16050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACRY_RS16055	COG2201	protein-glutamate methylesterase activity
ACRY_RS16060	COG0745	RESPONSE REGULATOR receiver
ACRY_RS16065	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACRY_RS16095	COG0564	pseudouridine synthase activity
ACRY_RS16145	COG3665	Urea carboxylase-associated protein
ACRY_RS16205	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACRY_RS16210	COG0583	DNA-binding transcription factor activity
ACRY_RS16225	COG0765	amino acid transport
ACRY_RS16240	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ACRY_RS16245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACRY_RS16250	COG0405	Gamma-glutamyltransferase
ACRY_RS16260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACRY_RS16290	COG0602	queuosine metabolic process
ACRY_RS16305	COG0237	dephospho-CoA kinase activity
ACRY_RS16310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACRY_RS16330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACRY_RS16340	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ACRY_RS16385	COG0667	Aldo Keto reductase
ACRY_RS16390	COG0583	DNA-binding transcription factor activity
ACRY_RS16395	COG3246	L-lysine catabolic process to acetate
ACRY_RS16400	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACRY_RS16410	COG1129	ABC transporter
ACRY_RS16420	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS16425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACRY_RS16430	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ACRY_RS16435	COG1696	Membrane protein involved in D-alanine export
ACRY_RS16450	COG3284	Transcriptional regulator
ACRY_RS16470	COG3791	Glutathione-dependent formaldehyde-activating
ACRY_RS16475	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ACRY_RS16480	COG4772	TonB-dependent receptor
ACRY_RS16485	COG0277	FAD linked oxidase domain protein
ACRY_RS16490	COG4993	Dehydrogenase
ACRY_RS16490	COG2010	Cytochrome c
ACRY_RS16500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACRY_RS16505	COG0175	sulfate reduction
ACRY_RS16510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACRY_RS16520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACRY_RS16520	COG1648	precorrin-2 dehydrogenase activity
ACRY_RS16525	COG1522	sequence-specific DNA binding
ACRY_RS16530	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACRY_RS16540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACRY_RS16560	COG2200	EAL domain
ACRY_RS16560	COG2203	Gaf domain
ACRY_RS16560	COG2199	diguanylate cyclase activity
ACRY_RS16575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACRY_RS16585	COG0745	RESPONSE REGULATOR receiver
ACRY_RS16610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACRY_RS16615	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACRY_RS16615	COG0022	dehydrogenase e1 component
ACRY_RS16620	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACRY_RS16630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACRY_RS16635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACRY_RS16640	COG2867	negative regulation of translational initiation
ACRY_RS16660	COG0667	Aldo Keto reductase
ACRY_RS16675	COG0028	Belongs to the TPP enzyme family
ACRY_RS16680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACRY_RS16690	COG1832	CoA-binding protein
ACRY_RS16700	COG1686	Belongs to the peptidase S11 family
ACRY_RS16720	COG1278	Cold shock
ACRY_RS16730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACRY_RS16750	COG2264	protein methyltransferase activity
ACRY_RS16755	COG0596	Alpha beta hydrolase
ACRY_RS16770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACRY_RS16775	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ACRY_RS16780	COG1138	Cytochrome C-type biogenesis protein
ACRY_RS16785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACRY_RS16790	COG3088	subunit of a heme lyase
ACRY_RS16805	COG0028	Belongs to the TPP enzyme family
ACRY_RS16820	COG1643	Atp-dependent helicase
ACRY_RS16835	COG2863	cytochrome
ACRY_RS16845	COG0604	alcohol dehydrogenase
ACRY_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS16845	COG3321	synthase
ACRY_RS16855	COG1127	ABC transporter
ACRY_RS16860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACRY_RS16865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACRY_RS16875	COG0305	Participates in initiation and elongation during chromosome replication
ACRY_RS16895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACRY_RS16900	COG0004	ammonium transporteR
ACRY_RS16910	COG0516	GMP reductase activity
ACRY_RS16910	COG0517	IMP dehydrogenase activity
ACRY_RS16915	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ACRY_RS16920	COG1902	pentaerythritol trinitrate reductase activity
ACRY_RS16925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACRY_RS16935	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACRY_RS16945	COG0583	DNA-binding transcription factor activity
ACRY_RS16950	COG0679	Auxin Efflux Carrier
ACRY_RS16955	COG2200	EAL domain
ACRY_RS16990	COG1139	Iron-sulfur cluster binding protein
ACRY_RS17000	COG0823	Involved in the tonB-independent uptake of proteins
ACRY_RS17010	COG0848	biopolymer transport protein
ACRY_RS17015	COG0811	peptide transport
ACRY_RS17020	COG0824	Thioesterase
ACRY_RS17025	COG2255	four-way junction helicase activity
ACRY_RS17030	COG0632	four-way junction helicase activity
ACRY_RS17035	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACRY_RS17040	COG0217	transcriptional regulatory protein
ACRY_RS17050	COG0438	transferase activity, transferring glycosyl groups
ACRY_RS17065	COG3624	Phosphonate C-P lyase system protein PhnG
ACRY_RS17075	COG3626	phosphonate metabolism
ACRY_RS17080	COG3627	carbon phosphorus lyase activity
ACRY_RS17085	COG4107	phosphonate C-P lyase system protein PhnK
ACRY_RS17090	COG4778	phosphonate C-P lyase system protein PhnL
ACRY_RS17095	COG3454	Phosphonate metabolism
ACRY_RS17105	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ACRY_RS17110	COG2188	Transcriptional regulator
ACRY_RS17115	COG1216	Glycosyl transferase, family 2
ACRY_RS17115	COG0438	transferase activity, transferring glycosyl groups
ACRY_RS17120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACRY_RS17125	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACRY_RS17130	COG0438	transferase activity, transferring glycosyl groups
ACRY_RS17130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACRY_RS17145	COG2130	NADP-dependent
ACRY_RS17165	COG0559	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS17180	COG0366	Alpha amylase catalytic
ACRY_RS17185	COG0366	Alpha amylase catalytic
ACRY_RS17190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACRY_RS17230	COG0408	coproporphyrinogen oxidase activity
ACRY_RS17250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACRY_RS17255	COG0450	alkyl hydroperoxide reductase
ACRY_RS17260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACRY_RS17270	COG0745	RESPONSE REGULATOR receiver
ACRY_RS17280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACRY_RS17295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACRY_RS17305	COG2204	response regulator
ACRY_RS17350	COG3409	Peptidoglycan-binding domain 1 protein
ACRY_RS17350	COG3267	Type II secretory pathway component ExeA
ACRY_RS17390	COG3284	Transcriptional regulator
ACRY_RS17395	COG1063	alcohol dehydrogenase
ACRY_RS17420	COG3254	rhamnose metabolic process
ACRY_RS17425	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS17430	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACRY_RS17450	COG4952	isomerase
ACRY_RS17455	COG1028	Short-chain dehydrogenase reductase Sdr
ACRY_RS17455	COG3347	Dehydrogenase
ACRY_RS17460	COG1070	Carbohydrate kinase
ACRY_RS17465	COG0840	transmembrane signaling receptor activity
ACRY_RS17465	COG0840	transmembrane signaling receptor activity
ACRY_RS17475	COG0484	heat shock protein binding
ACRY_RS17485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACRY_RS17490	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ACRY_RS17520	COG0395	ABC-type sugar transport system, permease component
ACRY_RS17530	COG1653	transport
ACRY_RS17535	COG2267	carboxylic ester hydrolase activity
ACRY_RS17540	COG2010	Cytochrome c
ACRY_RS17540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACRY_RS17545	COG2080	2 iron, 2 sulfur cluster binding
ACRY_RS17555	COG0456	acetyltransferase
ACRY_RS17560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACRY_RS17565	COG1917	Cupin 2, conserved barrel domain protein
ACRY_RS17570	COG5285	phytanoyl-CoA dioxygenase
ACRY_RS17575	COG0527	aspartate kinase activity
ACRY_RS17580	COG2814	Major facilitator Superfamily
ACRY_RS17595	COG1127	ABC transporter
ACRY_RS17600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACRY_RS17605	COG0861	Integral membrane protein TerC family
ACRY_RS17610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACRY_RS17660	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACRY_RS17665	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACRY_RS17705	COG0235	Class ii aldolase
ACRY_RS17710	COG2020	methyltransferase activity
ACRY_RS17715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACRY_RS17750	COG0737	Belongs to the 5'-nucleotidase family
ACRY_RS17785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACRY_RS17805	COG0436	Aminotransferase
ACRY_RS17815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACRY_RS17825	COG0039	L-malate dehydrogenase activity
ACRY_RS17925	COG2884	Cell division ATP-binding protein ftsE
ACRY_RS17940	COG0326	Molecular chaperone. Has ATPase activity
ACRY_RS17950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACRY_RS17965	COG1914	H( )-stimulated, divalent metal cation uptake system
ACRY_RS18010	COG1309	transcriptional regulator
ACRY_RS18025	COG0268	Binds directly to 16S ribosomal RNA
ACRY_RS18085	COG1192	Involved in chromosome partitioning
ACRY_RS18100	COG3012	SEC-C Motif Domain Protein
ACRY_RS18125	COG2197	response regulator
