locus-tag	class	description
MQE22_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MQE22_RS00010	COG0592	DNA-directed DNA polymerase activity
MQE22_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MQE22_RS00025	COG0493	'glutamate synthase
MQE22_RS00025	COG0543	2 iron, 2 sulfur cluster binding
MQE22_RS00045	COG4804	nuclease activity
MQE22_RS00055	COG2814	Major facilitator Superfamily
MQE22_RS00060	COG3842	ATPase activity
MQE22_RS00065	COG0395	ABC-type sugar transport system, permease component
MQE22_RS00070	COG1175	transmembrane transport
MQE22_RS00085	COG1172	Belongs to the binding-protein-dependent transport system permease family
MQE22_RS00095	COG1879	ABC-type sugar transport system periplasmic component
MQE22_RS00100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MQE22_RS00105	COG1193	negative regulation of DNA recombination
MQE22_RS00110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MQE22_RS00120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MQE22_RS00125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MQE22_RS00130	COG2376	Dihydroxyacetone kinase
MQE22_RS00135	COG1461	Dihydroxyacetone kinase
MQE22_RS00140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MQE22_RS00140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MQE22_RS00145	COG0598	Magnesium transport protein CorA
MQE22_RS00150	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MQE22_RS00155	COG2894	cell division
MQE22_RS00160	COG0850	regulation of cytokinetic process
MQE22_RS00165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MQE22_RS00175	COG2922	Belongs to the Smg family
MQE22_RS00180	COG0758	DNA mediated transformation
MQE22_RS00190	COG0242	peptide deformylase activity
MQE22_RS00195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MQE22_RS00200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MQE22_RS00200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MQE22_RS00205	COG5000	phosphorelay sensor kinase activity
MQE22_RS00210	COG2204	response regulator
MQE22_RS00215	COG0521	Mo-molybdopterin cofactor biosynthetic process
MQE22_RS00220	COG0445	tRNA wobble uridine modification
MQE22_RS00225	COG0357	Ribosomal RNA small subunit methyltransferase G
MQE22_RS00230	COG1192	Involved in chromosome partitioning
MQE22_RS00235	COG1475	DNA binding
MQE22_RS00245	COG0356	it plays a direct role in the translocation of protons across the membrane
MQE22_RS00255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MQE22_RS00260	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MQE22_RS00265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MQE22_RS00270	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MQE22_RS00285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MQE22_RS00295	COG0583	DNA-binding transcription factor activity
MQE22_RS00300	COG0477	Major facilitator Superfamily
MQE22_RS00310	COG1566	PFAM secretion protein HlyD family protein
MQE22_RS00315	COG1566	PFAM secretion protein HlyD family protein
MQE22_RS00325	COG3189	MarR family transcriptional regulator
MQE22_RS00340	COG2181	nitrate reductase activity
MQE22_RS00345	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MQE22_RS00350	COG1140	nitrate reductase beta subunit
MQE22_RS00355	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MQE22_RS00400	COG0509	glycine decarboxylation via glycine cleavage system
MQE22_RS00420	COG1017	nitric oxide dioxygenase activity
MQE22_RS00420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MQE22_RS00490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MQE22_RS00490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MQE22_RS00560	COG0659	secondary active sulfate transmembrane transporter activity
MQE22_RS00565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MQE22_RS00600	COG0210	DNA helicase
MQE22_RS00630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE22_RS00645	COG1970	mechanosensitive ion channel activity
MQE22_RS00650	COG1322	Protein conserved in bacteria
MQE22_RS00655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MQE22_RS00660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MQE22_RS00665	COG0483	inositol monophosphate 1-phosphatase activity
MQE22_RS00670	COG1494	fructose-1,6-bisphosphatase
MQE22_RS00675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MQE22_RS00680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MQE22_RS00685	COG0126	phosphoglycerate kinase activity
MQE22_RS00690	COG0469	pyruvate kinase activity
MQE22_RS00700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MQE22_RS00705	COG0546	phosphoglycolate phosphatase activity
MQE22_RS00710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MQE22_RS00720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MQE22_RS00725	COG0134	indole-3-glycerol-phosphate synthase activity
MQE22_RS00730	COG1765	OsmC-like protein
MQE22_RS00735	COG1959	2 iron, 2 sulfur cluster binding
MQE22_RS00740	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MQE22_RS00750	COG2945	thiolester hydrolase activity
MQE22_RS00755	COG1131	(ABC) transporter
MQE22_RS00760	COG0842	Transport permease protein
MQE22_RS00800	COG4969	Belongs to the N-Me-Phe pilin family
MQE22_RS00820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MQE22_RS00825	COG2084	Dehydrogenase
MQE22_RS00830	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MQE22_RS00845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MQE22_RS00855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MQE22_RS00860	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MQE22_RS00860	COG3264	Mechanosensitive ion channel
MQE22_RS00875	COG2177	Part of the ABC transporter FtsEX involved in
MQE22_RS00880	COG2884	Cell division ATP-binding protein ftsE
MQE22_RS00885	COG0552	protein localization to endoplasmic reticulum
MQE22_RS00890	COG0742	ribosomal rna small subunit methyltransferase
MQE22_RS00895	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MQE22_RS00900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MQE22_RS00905	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MQE22_RS00910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MQE22_RS00915	COG2890	protein-(glutamine-N5) methyltransferase activity
MQE22_RS00920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MQE22_RS00925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MQE22_RS00935	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MQE22_RS00940	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MQE22_RS00950	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MQE22_RS00965	COG1686	Belongs to the peptidase S11 family
MQE22_RS00970	COG0166	Belongs to the GPI family
MQE22_RS00975	COG1271	oxidase subunit
MQE22_RS00980	COG1294	oxidase, subunit
MQE22_RS00995	COG1217	gtp-binding protein TYPA
MQE22_RS01005	COG2967	ApaG domain
MQE22_RS01010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MQE22_RS01030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MQE22_RS01035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MQE22_RS01050	COG0436	Aminotransferase
MQE22_RS01060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MQE22_RS01070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MQE22_RS01075	COG2217	Heavy metal translocating P-type atpase
MQE22_RS01085	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MQE22_RS01090	COG0243	molybdopterin cofactor binding
MQE22_RS01100	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MQE22_RS01115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MQE22_RS01125	COG1136	(ABC) transporter
MQE22_RS01135	COG0658	competence protein
MQE22_RS01135	COG2333	competence protein COMEC
MQE22_RS01140	COG0811	peptide transport
MQE22_RS01145	COG0848	biopolymer transport protein
MQE22_RS01160	COG1663	tetraacyldisaccharide 4'-kinase activity
MQE22_RS01165	COG2835	tetraacyldisaccharide 4'-kinase activity
MQE22_RS01170	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MQE22_RS01185	COG0542	response to heat
MQE22_RS01190	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MQE22_RS01195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MQE22_RS01205	COG0793	Belongs to the peptidase S41A family
MQE22_RS01215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MQE22_RS01220	COG0058	SHG alpha-glucan phosphorylase activity
MQE22_RS01240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MQE22_RS01250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MQE22_RS01255	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MQE22_RS01315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MQE22_RS01320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MQE22_RS01330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MQE22_RS01340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MQE22_RS01400	COG0438	transferase activity, transferring glycosyl groups
MQE22_RS01405	COG0297	glycogen (starch) synthase activity
MQE22_RS01410	COG0110	maltose O-acetyltransferase activity
MQE22_RS01415	COG0297	glycogen (starch) synthase activity
MQE22_RS01425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MQE22_RS01430	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MQE22_RS01460	COG1278	Cold shock
MQE22_RS01510	COG2204	response regulator
MQE22_RS01515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MQE22_RS01520	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MQE22_RS01530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MQE22_RS01535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MQE22_RS01545	COG1449	Belongs to the glycosyl hydrolase 57 family
MQE22_RS01550	COG1940	carbohydrate kinase activity
MQE22_RS01555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MQE22_RS01565	COG2733	membrane
MQE22_RS01570	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MQE22_RS01575	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MQE22_RS01580	COG1702	phosphate starvation-inducible protein PhoH
MQE22_RS01585	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MQE22_RS01590	COG4535	Mg2 and Co2 transporter CorC
MQE22_RS01595	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MQE22_RS01645	COG0616	signal peptide processing
MQE22_RS01660	COG0033	Phosphoglucomutase
MQE22_RS01675	COG2801	Transposase and inactivated derivatives
MQE22_RS01700	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MQE22_RS01710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MQE22_RS01715	COG0228	four-way junction DNA binding
MQE22_RS01720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MQE22_RS01725	COG0336	Belongs to the RNA methyltransferase TrmD family
MQE22_RS01730	COG0335	large ribosomal subunit rRNA binding
MQE22_RS01740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MQE22_RS01750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MQE22_RS01755	COG3118	belongs to the thioredoxin family
MQE22_RS01770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MQE22_RS01775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MQE22_RS01780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MQE22_RS01780	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MQE22_RS01795	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MQE22_RS01800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MQE22_RS01815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MQE22_RS01840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MQE22_RS01860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MQE22_RS01865	COG0081	regulation of translation
MQE22_RS01870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MQE22_RS01875	COG0222	ribosome binding
MQE22_RS01880	COG0085	RNA polymerase activity
MQE22_RS01885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MQE22_RS01890	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MQE22_RS01895	COG0049	tRNA binding
MQE22_RS01900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MQE22_RS01905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MQE22_RS01910	COG0051	transcription antitermination factor activity, RNA binding
MQE22_RS01915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MQE22_RS01920	COG0088	Forms part of the polypeptide exit tunnel
MQE22_RS01925	COG0089	rRNA binding
MQE22_RS01930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MQE22_RS01935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MQE22_RS01940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MQE22_RS01945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MQE22_RS01950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MQE22_RS01955	COG0255	Belongs to the universal ribosomal protein uL29 family
MQE22_RS01960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MQE22_RS01965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MQE22_RS01970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MQE22_RS01975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MQE22_RS01980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MQE22_RS01985	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MQE22_RS01990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MQE22_RS01995	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MQE22_RS02000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MQE22_RS02005	COG1841	ribosomal large subunit assembly
MQE22_RS02010	COG0200	Binds to the 23S rRNA
MQE22_RS02015	COG0201	protein transport
MQE22_RS02020	COG0563	adenylate kinase activity
MQE22_RS02025	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MQE22_RS02030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MQE22_RS02035	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MQE22_RS02040	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MQE22_RS02045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MQE22_RS02050	COG0202	RNA polymerase activity
MQE22_RS02055	COG0203	ribosomal protein L17
MQE22_RS02065	COG0629	single-stranded DNA binding
MQE22_RS02080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MQE22_RS02105	COG2995	paraquat-inducible protein a
MQE22_RS02110	COG0305	Participates in initiation and elongation during chromosome replication
MQE22_RS02115	COG0359	binds to the 23S rRNA
MQE22_RS02125	COG0360	Binds together with S18 to 16S ribosomal RNA
MQE22_RS02130	COG1472	Belongs to the glycosyl hydrolase 3 family
MQE22_RS02135	COG0531	amino acid
MQE22_RS02145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MQE22_RS02170	COG0363	glucosamine-6-phosphate deaminase activity
MQE22_RS02175	COG0330	HflC and HflK could
MQE22_RS02185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MQE22_RS02190	COG0805	protein transport
MQE22_RS02195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MQE22_RS02200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MQE22_RS02205	COG0140	phosphoribosyl-ATP diphosphatase activity
MQE22_RS02205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MQE22_RS02210	COG0107	imidazoleglycerol-phosphate synthase activity
MQE22_RS02215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MQE22_RS02220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MQE22_RS02225	COG0131	Imidazoleglycerol-phosphate dehydratase
MQE22_RS02230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MQE22_RS02235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MQE22_RS02240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MQE22_RS02245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MQE22_RS02250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MQE22_RS02255	COG0271	Belongs to the BolA IbaG family
MQE22_RS02260	COG0842	Transport permease protein
MQE22_RS02265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MQE22_RS02270	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MQE22_RS02275	COG3178	'Phosphotransferase
MQE22_RS02280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MQE22_RS02300	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MQE22_RS02330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MQE22_RS02335	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MQE22_RS02340	COG1660	Displays ATPase and GTPase activities
MQE22_RS02350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MQE22_RS02360	COG0741	lytic transglycosylase activity
MQE22_RS02360	COG1388	LysM domain
MQE22_RS02365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MQE22_RS02370	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MQE22_RS02375	COG0538	isocitrate dehydrogenase activity
MQE22_RS02380	COG0045	succinate-CoA ligase (ADP-forming) activity
MQE22_RS02390	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MQE22_RS02395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MQE22_RS02395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MQE22_RS02400	COG0347	Belongs to the P(II) protein family
MQE22_RS02410	COG0564	pseudouridine synthase activity
MQE22_RS02425	COG1850	ribulose-bisphosphate carboxylase activity
MQE22_RS02435	COG0235	Class ii aldolase
MQE22_RS02445	COG0242	peptide deformylase activity
MQE22_RS02495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MQE22_RS02520	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MQE22_RS02525	COG2154	pterin-4-alpha-carbinolamine dehydratase
MQE22_RS02545	COG0189	ligase activity
MQE22_RS02555	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MQE22_RS02560	COG0751	glycine-tRNA ligase activity
MQE22_RS02610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MQE22_RS02615	COG0321	lipoyl(octanoyl) transferase activity
MQE22_RS02620	COG2921	Belongs to the UPF0250 family
MQE22_RS02625	COG1686	Belongs to the peptidase S11 family
MQE22_RS02630	COG0772	Belongs to the SEDS family
MQE22_RS02635	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MQE22_RS02645	COG1077	Cell shape determining protein MreB Mrl
MQE22_RS02650	COG0737	Belongs to the 5'-nucleotidase family
MQE22_RS02660	COG3258	Cytochrome c
MQE22_RS02680	COG2204	response regulator
MQE22_RS02685	COG5000	phosphorelay sensor kinase activity
MQE22_RS02695	COG0315	cyclic pyranopterin monophosphate synthase activity
MQE22_RS02705	COG0243	molybdopterin cofactor binding
MQE22_RS02710	COG0437	4 iron, 4 sulfur cluster binding
MQE22_RS02720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MQE22_RS02725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MQE22_RS02730	COG0425	Belongs to the sulfur carrier protein TusA family
MQE22_RS02735	COG2210	Belongs to the sulfur carrier protein TusA family
MQE22_RS02765	COG2048	Heterodisulfide reductase, subunit B
MQE22_RS02770	COG0509	glycine decarboxylation via glycine cleavage system
MQE22_RS02780	COG0509	glycine decarboxylation via glycine cleavage system
MQE22_RS02790	COG0095	Lipoate-protein ligase
MQE22_RS02795	COG0644	oxidoreductase
MQE22_RS02845	COG0123	including yeast histone deacetylase and acetoin utilization protein
MQE22_RS02860	COG0583	DNA-binding transcription factor activity
MQE22_RS02875	COG0586	Pfam SNARE associated Golgi protein
MQE22_RS02880	COG3152	Membrane
MQE22_RS02895	COG0791	NLP P60 protein
MQE22_RS02900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MQE22_RS02910	COG1199	ATP-dependent helicase activity
MQE22_RS02935	COG2801	Transposase and inactivated derivatives
MQE22_RS02940	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MQE22_RS02945	COG0193	aminoacyl-tRNA hydrolase activity
MQE22_RS02950	COG0012	GTP binding
MQE22_RS02980	COG0494	nUDIX hydrolase
MQE22_RS02990	COG1187	pseudouridine synthase activity
MQE22_RS02995	COG2957	Belongs to the agmatine deiminase family
MQE22_RS03005	COG0210	DNA helicase
MQE22_RS03010	COG0268	Binds directly to 16S ribosomal RNA
MQE22_RS03015	COG0768	penicillin binding
MQE22_RS03035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MQE22_RS03040	COG1692	metallophosphoesterase
MQE22_RS03055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MQE22_RS03075	COG0442	prolyl-tRNA aminoacylation
MQE22_RS03100	COG1028	Short-chain dehydrogenase reductase Sdr
MQE22_RS03110	COG0142	geranyltranstransferase activity
MQE22_RS03140	COG0488	(ABC) transporter
MQE22_RS03150	COG1573	uracil-dna glycosylase
MQE22_RS03155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MQE22_RS03160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MQE22_RS03170	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MQE22_RS03190	COG0848	biopolymer transport protein
MQE22_RS03195	COG0811	peptide transport
MQE22_RS03200	COG4772	TonB-dependent receptor
MQE22_RS03210	COG1561	YicC-like family, N-terminal region
MQE22_RS03220	COG1758	RNA polymerase activity
MQE22_RS03225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MQE22_RS03240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MQE22_RS03245	COG2161	toxin-antitoxin pair type II binding
MQE22_RS03250	COG4115	mRNA cleavage
MQE22_RS03260	COG2199	diguanylate cyclase activity
MQE22_RS03270	COG0628	permease
MQE22_RS03280	COG0613	PHP domain protein
MQE22_RS03285	COG0628	permease
MQE22_RS03300	COG0084	hydrolase, TatD family'
MQE22_RS03305	COG0321	lipoyl(octanoyl) transferase activity
MQE22_RS03305	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MQE22_RS03330	COG0277	FAD linked oxidase domain protein
MQE22_RS03335	COG0277	FAD linked oxidase domain protein
MQE22_RS03340	COG0247	lactate metabolic process
MQE22_RS03345	COG1929	Belongs to the glycerate kinase type-1 family
MQE22_RS03360	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MQE22_RS03375	COG1294	oxidase, subunit
MQE22_RS03400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MQE22_RS03405	COG0156	8-amino-7-oxononanoate synthase activity
MQE22_RS03410	COG0438	transferase activity, transferring glycosyl groups
MQE22_RS03430	COG0662	Cupin 2, conserved barrel domain protein
MQE22_RS03430	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MQE22_RS03455	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MQE22_RS03490	COG0730	response to heat
MQE22_RS03510	COG2814	Major facilitator Superfamily
MQE22_RS03525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MQE22_RS03530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MQE22_RS03555	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MQE22_RS03560	COG3258	Cytochrome c
MQE22_RS03570	COG1333	cytochrome c biogenesis protein
MQE22_RS03580	COG0737	Belongs to the 5'-nucleotidase family
MQE22_RS03600	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MQE22_RS03605	COG0525	valine-tRNA ligase activity
MQE22_RS03620	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MQE22_RS03655	COG1965	Belongs to the frataxin family
MQE22_RS03660	COG0514	ATP-dependent DNA helicase (RecQ)
MQE22_RS03670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MQE22_RS03680	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MQE22_RS03685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MQE22_RS03690	COG4191	Histidine kinase
MQE22_RS03695	COG2204	response regulator
MQE22_RS03705	COG1657	PFAM Prenyltransferase squalene oxidase
MQE22_RS03715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MQE22_RS03750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MQE22_RS03765	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MQE22_RS03770	COG0154	amidase activity
MQE22_RS03775	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MQE22_RS03785	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MQE22_RS03790	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
MQE22_RS03795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MQE22_RS03800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MQE22_RS03830	COG0590	tRNA wobble adenosine to inosine editing
MQE22_RS03835	COG0432	Pfam Uncharacterised protein family UPF0047
MQE22_RS03845	COG1193	negative regulation of DNA recombination
MQE22_RS03850	COG0028	Belongs to the TPP enzyme family
MQE22_RS03860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MQE22_RS03865	COG0688	phosphatidylethanolamine metabolic process
MQE22_RS03870	COG1183	phosphatidylcholine synthase activity
MQE22_RS03890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MQE22_RS03895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MQE22_RS03905	COG0450	alkyl hydroperoxide reductase
MQE22_RS03915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MQE22_RS03930	COG1850	ribulose-bisphosphate carboxylase activity
MQE22_RS03935	COG4451	ribulose bisphosphate carboxylase, small
MQE22_RS03960	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MQE22_RS03965	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MQE22_RS03970	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MQE22_RS04000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MQE22_RS04030	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MQE22_RS04050	COG1324	tolerance protein
MQE22_RS04055	COG4232	protein-disulfide reductase activity
MQE22_RS04070	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MQE22_RS04085	COG0167	dihydroorotate dehydrogenase activity
MQE22_RS04090	COG0408	coproporphyrinogen oxidase activity
MQE22_RS04095	COG0009	L-threonylcarbamoyladenylate synthase
MQE22_RS04100	COG0151	Belongs to the GarS family
MQE22_RS04105	COG0138	bifunctional purine biosynthesis protein purh
MQE22_RS04110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MQE22_RS04115	COG0529	Catalyzes the synthesis of activated sulfate
MQE22_RS04115	COG2046	Belongs to the sulfate adenylyltransferase family
MQE22_RS04125	COG1247	-acetyltransferase
MQE22_RS04130	COG0582	viral genome integration into host DNA
MQE22_RS04150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MQE22_RS04185	COG1193	negative regulation of DNA recombination
MQE22_RS04190	COG3619	membrane
MQE22_RS04195	COG0277	FAD linked oxidase domain protein
MQE22_RS04200	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MQE22_RS04205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MQE22_RS04210	COG1428	Deoxynucleoside kinase
MQE22_RS04220	COG0617	tRNA 3'-terminal CCA addition
MQE22_RS04230	COG3180	Ammonia monooxygenase
MQE22_RS04240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MQE22_RS04240	COG0519	Catalyzes the synthesis of GMP from XMP
MQE22_RS04270	COG0697	spore germination
MQE22_RS04275	COG1902	pentaerythritol trinitrate reductase activity
MQE22_RS04280	COG0412	Dienelactone hydrolase
MQE22_RS04290	COG0084	hydrolase, TatD family'
MQE22_RS04295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MQE22_RS04310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MQE22_RS04320	COG0640	Transcriptional regulator
MQE22_RS04345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MQE22_RS04350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MQE22_RS04360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MQE22_RS04385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MQE22_RS04390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MQE22_RS04395	COG0196	riboflavin kinase activity
MQE22_RS04405	COG0741	lytic transglycosylase activity
MQE22_RS04415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MQE22_RS04420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MQE22_RS04425	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MQE22_RS04430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MQE22_RS04445	COG0840	transmembrane signaling receptor activity
MQE22_RS04445	COG5278	phosphoserine phosphatase activity
MQE22_RS04450	COG0784	Response regulator, receiver
MQE22_RS04450	COG0835	chemotaxis
MQE22_RS04480	COG0643	Histidine kinase
MQE22_RS04480	COG0784	Response regulator, receiver
MQE22_RS04480	COG2198	Histidine kinase
MQE22_RS04490	COG0745	RESPONSE REGULATOR receiver
MQE22_RS04510	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MQE22_RS04515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MQE22_RS04535	COG1815	bacterial-type flagellum-dependent cell motility
MQE22_RS04540	COG1558	bacterial-type flagellum-dependent cell motility
MQE22_RS04545	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MQE22_RS04565	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MQE22_RS04570	COG1706	bacterial-type flagellum-dependent cell motility
MQE22_RS04575	COG1705	Flagellar rod assembly protein muramidase FlgJ
MQE22_RS04575	COG3951	Flagellar rod assembly protein muramidase FlgJ
MQE22_RS04595	COG1216	Glycosyl transferase, family 2
MQE22_RS04595	COG0438	transferase activity, transferring glycosyl groups
MQE22_RS04635	COG3852	Histidine kinase
MQE22_RS04645	COG1677	Flagellar hook-basal body complex protein FliE
MQE22_RS04650	COG1766	The M ring may be actively involved in energy transduction
MQE22_RS04655	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MQE22_RS04700	COG1987	bacterial-type flagellum assembly
MQE22_RS04735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MQE22_RS04750	COG1487	ribonuclease activity
MQE22_RS04755	COG1064	alcohol dehydrogenase
MQE22_RS04760	COG0504	CTP synthase activity
MQE22_RS04765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MQE22_RS04770	COG0148	phosphopyruvate hydratase activity
MQE22_RS04775	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MQE22_RS04780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MQE22_RS04790	COG0322	excinuclease ABC activity
MQE22_RS04800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MQE22_RS04805	COG1074	ATP-dependent DNA helicase activity
MQE22_RS04810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MQE22_RS04850	COG2363	Small membrane protein
MQE22_RS04855	COG0616	signal peptide processing
MQE22_RS04860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MQE22_RS04865	COG0314	molybdopterin synthase activity
MQE22_RS04870	COG1666	GTP binding
MQE22_RS04880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MQE22_RS04890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MQE22_RS04895	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MQE22_RS04900	COG0714	Associated with various cellular activities
MQE22_RS04915	COG1132	(ABC) transporter
MQE22_RS04920	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MQE22_RS04945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MQE22_RS04950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MQE22_RS04960	COG1193	negative regulation of DNA recombination
MQE22_RS04965	COG0358	DNA primase activity
MQE22_RS04990	COG4988	ABC transporter
MQE22_RS04995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MQE22_RS05015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MQE22_RS05030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MQE22_RS05035	COG0481	GTPase activity
MQE22_RS05040	COG0681	Belongs to the peptidase S26 family
MQE22_RS05065	COG2022	thiamine diphosphate biosynthetic process
MQE22_RS05075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MQE22_RS05080	COG0163	prenyltransferase activity
MQE22_RS05085	COG1127	ABC transporter
MQE22_RS05090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MQE22_RS05105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MQE22_RS05120	COG0577	efflux transmembrane transporter activity
MQE22_RS05125	COG1136	(ABC) transporter
MQE22_RS05140	COG0459	protein refolding
MQE22_RS05145	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MQE22_RS05170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MQE22_RS05180	COG1058	Belongs to the CinA family
MQE22_RS05180	COG1546	Belongs to the CinA family
MQE22_RS05185	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MQE22_RS05190	COG2137	regulation of response to DNA damage stimulus
MQE22_RS05220	COG2814	Major facilitator Superfamily
MQE22_RS05230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MQE22_RS05245	COG0322	excinuclease ABC activity
MQE22_RS05265	COG0148	phosphopyruvate hydratase activity
MQE22_RS05270	COG0469	pyruvate kinase activity
MQE22_RS05280	COG1105	Belongs to the carbohydrate kinase PfkB family
MQE22_RS05285	COG0280	phosphate acetyltransferase
MQE22_RS05290	COG2814	Major facilitator Superfamily
MQE22_RS05295	COG1914	H( )-stimulated, divalent metal cation uptake system
MQE22_RS05300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MQE22_RS05305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE22_RS05325	COG0477	Major facilitator Superfamily
MQE22_RS05345	COG2353	YceI-like domain
MQE22_RS05350	COG0655	NAD(P)H dehydrogenase (quinone) activity
MQE22_RS05410	COG0745	RESPONSE REGULATOR receiver
MQE22_RS05415	COG2205	protein histidine kinase activity
MQE22_RS05425	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MQE22_RS05435	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MQE22_RS05445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MQE22_RS05475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MQE22_RS05500	COG0509	glycine decarboxylation via glycine cleavage system
MQE22_RS05520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MQE22_RS05520	COG1017	nitric oxide dioxygenase activity
MQE22_RS05550	COG4372	Transposase
MQE22_RS05565	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS05570	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MQE22_RS05570	COG3261	NADH dehydrogenase
MQE22_RS05575	COG0651	ATP synthesis coupled electron transport
MQE22_RS05585	COG0650	Formate hydrogenlyase subunit 4
MQE22_RS05590	COG0651	ATP synthesis coupled electron transport
MQE22_RS05610	COG1850	ribulose-bisphosphate carboxylase activity
MQE22_RS05620	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MQE22_RS05625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MQE22_RS05630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MQE22_RS05630	COG0574	Belongs to the PEP-utilizing enzyme family
MQE22_RS05640	COG0574	Belongs to the PEP-utilizing enzyme family
MQE22_RS05640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MQE22_RS05655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MQE22_RS05655	COG0574	Belongs to the PEP-utilizing enzyme family
MQE22_RS05670	COG2814	Major facilitator Superfamily
MQE22_RS05680	COG0531	amino acid
MQE22_RS05685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MQE22_RS05715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MQE22_RS05730	COG2801	Transposase and inactivated derivatives
MQE22_RS05735	COG1598	PFAM Uncharacterised protein family UPF0150
MQE22_RS05740	COG4372	Transposase
MQE22_RS05755	COG3344	reverse transcriptase
MQE22_RS05790	COG1845	cytochrome c oxidase, subunit III
MQE22_RS05795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MQE22_RS05800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MQE22_RS05810	COG0477	Major facilitator Superfamily
MQE22_RS05830	COG0811	peptide transport
MQE22_RS05835	COG0848	biopolymer transport protein
MQE22_RS05860	COG2188	Transcriptional regulator
MQE22_RS05865	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MQE22_RS05875	COG3454	Phosphonate metabolism
MQE22_RS05880	COG4778	phosphonate C-P lyase system protein PhnL
MQE22_RS05885	COG4107	phosphonate C-P lyase system protein PhnK
MQE22_RS05890	COG3627	carbon phosphorus lyase activity
MQE22_RS05895	COG3626	phosphonate metabolism
MQE22_RS05915	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MQE22_RS05920	COG1196	nuclear chromosome segregation
MQE22_RS05930	COG2223	nitrite transmembrane transporter activity
MQE22_RS05935	COG1722	exodeoxyribonuclease VII activity
MQE22_RS05940	COG0142	geranyltranstransferase activity
MQE22_RS05945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MQE22_RS05950	COG1469	GTP cyclohydrolase I activity
MQE22_RS05955	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MQE22_RS05960	COG2814	Major facilitator Superfamily
MQE22_RS05965	COG0542	response to heat
MQE22_RS05970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MQE22_RS05975	COG0308	aminopeptidase N
MQE22_RS05995	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MQE22_RS06000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MQE22_RS06015	COG2719	SpoVR family
MQE22_RS06020	COG2718	Belongs to the UPF0229 family
MQE22_RS06025	COG2766	serine protein kinase
MQE22_RS06035	COG0842	Transport permease protein
MQE22_RS06040	COG0842	Transport permease protein
MQE22_RS06045	COG1131	(ABC) transporter
MQE22_RS06085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MQE22_RS06090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MQE22_RS06095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MQE22_RS06100	COG0004	ammonium transporteR
MQE22_RS06105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MQE22_RS06105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MQE22_RS06110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MQE22_RS06115	COG2239	Acts as a magnesium transporter
MQE22_RS06120	COG0802	atpase or kinase
MQE22_RS06125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MQE22_RS06130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MQE22_RS06140	COG1289	transmembrane transporter activity
MQE22_RS06150	COG1566	PFAM secretion protein HlyD family protein
MQE22_RS06155	COG0571	ribonuclease III activity
MQE22_RS06165	COG1381	Involved in DNA repair and RecF pathway recombination
MQE22_RS06170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MQE22_RS06175	COG0736	holo-[acyl-carrier-protein] synthase activity
MQE22_RS06190	COG0037	tRNA processing
MQE22_RS06195	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MQE22_RS06205	COG1538	Outer membrane efflux protein
MQE22_RS06235	COG0076	glutamate decarboxylase activity
MQE22_RS06265	COG3220	belongs to the UPF0276 family
MQE22_RS06290	COG1335	isochorismatase
MQE22_RS06360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MQE22_RS06365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE22_RS06375	COG0436	Aminotransferase
MQE22_RS06385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MQE22_RS06395	COG1187	pseudouridine synthase activity
MQE22_RS06415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MQE22_RS06445	COG0729	surface antigen
MQE22_RS06480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MQE22_RS06480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MQE22_RS06500	COG1132	(ABC) transporter
MQE22_RS06515	COG2860	membrane
MQE22_RS06520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MQE22_RS06535	COG0587	DNA-directed DNA polymerase activity
MQE22_RS06540	COG1113	amino acid transport
MQE22_RS06545	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MQE22_RS06545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MQE22_RS06545	COG0506	proline dehydrogenase activity
MQE22_RS06550	COG0531	amino acid
MQE22_RS06555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MQE22_RS06560	COG3264	Mechanosensitive ion channel
MQE22_RS06560	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MQE22_RS06570	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MQE22_RS06575	COG0009	L-threonylcarbamoyladenylate synthase
MQE22_RS06580	COG1994	Peptidase M50
MQE22_RS06585	COG0180	Tryptophanyl-tRNA synthetase
MQE22_RS06590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MQE22_RS06595	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MQE22_RS06600	COG0446	pyridine nucleotide-disulphide oxidoreductase
MQE22_RS06615	COG2915	High frequency lysogenization protein hflD homolog
MQE22_RS06620	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MQE22_RS06625	COG0024	Methionine aminopeptidase
MQE22_RS06630	COG1489	DNA binding
MQE22_RS06635	COG0583	DNA-binding transcription factor activity
MQE22_RS06650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MQE22_RS06655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MQE22_RS06665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MQE22_RS06670	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MQE22_RS06675	COG1166	arginine decarboxylase activity
MQE22_RS06680	COG0179	Fumarylacetoacetate (FAA) hydrolase
MQE22_RS06690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MQE22_RS06710	COG4654	Cytochrome c, class I
MQE22_RS06730	COG0791	NLP P60 protein
MQE22_RS06735	COG2951	lytic endotransglycosylase activity
MQE22_RS06740	COG0402	S-adenosylhomocysteine deaminase activity
MQE22_RS06745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MQE22_RS06750	COG0546	phosphoglycolate phosphatase activity
MQE22_RS06765	COG2171	N-acyltransferase activity
MQE22_RS06770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MQE22_RS06785	COG0574	Belongs to the PEP-utilizing enzyme family
MQE22_RS06785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MQE22_RS06790	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MQE22_RS06800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MQE22_RS06815	COG0022	dehydrogenase e1 component
MQE22_RS06820	COG0508	dehydrogenase complex catalyzes the overall conversion of
MQE22_RS06825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MQE22_RS06845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MQE22_RS06850	COG1061	Type III restriction enzyme res subunit
MQE22_RS06860	COG1002	Type II restriction enzyme, methylase subunits
MQE22_RS06865	COG3093	addiction module antidote protein HigA
MQE22_RS06875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MQE22_RS06990	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
MQE22_RS07020	COG0582	viral genome integration into host DNA
MQE22_RS07030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MQE22_RS07050	COG3220	belongs to the UPF0276 family
MQE22_RS07085	COG0415	Belongs to the DNA photolyase family
MQE22_RS07110	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MQE22_RS07120	COG2026	Addiction module toxin, RelE StbE family
MQE22_RS07145	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MQE22_RS07155	COG0067	glutamate synthase
MQE22_RS07155	COG0069	glutamate synthase activity
MQE22_RS07155	COG0070	glutamate synthase
MQE22_RS07160	COG0493	'glutamate synthase
MQE22_RS07165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MQE22_RS07185	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MQE22_RS07200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MQE22_RS07205	COG1923	regulation of RNA biosynthetic process
MQE22_RS07210	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MQE22_RS07215	COG0424	maF-like protein
MQE22_RS07250	COG2062	phosphohistidine phosphatase, SixA
MQE22_RS07260	COG1160	GTP binding
MQE22_RS07265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MQE22_RS07275	COG0124	histidyl-tRNA synthetase
MQE22_RS07280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MQE22_RS07295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MQE22_RS07300	COG0105	UTP biosynthetic process
MQE22_RS07310	COG0446	pyridine nucleotide-disulphide oxidoreductase
MQE22_RS07325	COG0037	tRNA processing
MQE22_RS07330	COG0825	malonyl-CoA metabolic process
MQE22_RS07340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MQE22_RS07345	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MQE22_RS07365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MQE22_RS07370	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MQE22_RS07390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MQE22_RS07395	COG0575	Belongs to the CDS family
MQE22_RS07400	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MQE22_RS07410	COG0528	UMP kinase activity
MQE22_RS07415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MQE22_RS07420	COG0052	Belongs to the universal ribosomal protein uS2 family
MQE22_RS07435	COG0704	Plays a role in the regulation of phosphate uptake
MQE22_RS07440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MQE22_RS07445	COG5002	protein histidine kinase activity
MQE22_RS07450	COG0745	RESPONSE REGULATOR receiver
MQE22_RS07455	COG0482	sulfurtransferase activity
MQE22_RS07470	COG0443	Heat shock 70 kDa protein
MQE22_RS07485	COG0822	iron-sulfur transferase activity
MQE22_RS07490	COG1104	cysteine desulfurase activity
MQE22_RS07495	COG1959	2 iron, 2 sulfur cluster binding
MQE22_RS07505	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MQE22_RS07520	COG2917	probably involved in intracellular septation
MQE22_RS07525	COG2350	Protein conserved in bacteria
MQE22_RS07530	COG0271	Belongs to the BolA IbaG family
MQE22_RS07535	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MQE22_RS07535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MQE22_RS07545	COG0129	dihydroxy-acid dehydratase activity
MQE22_RS07550	COG0628	permease
MQE22_RS07555	COG0281	malic enzyme
MQE22_RS07555	COG0280	phosphate acetyltransferase
MQE22_RS07560	COG0254	rRNA binding
MQE22_RS07575	COG3511	phospholipase C
MQE22_RS07585	COG3706	GGDEF domain
MQE22_RS07615	COG2200	EAL domain
MQE22_RS07645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MQE22_RS07650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MQE22_RS07655	COG1862	Preprotein translocase
MQE22_RS07665	COG0343	queuine tRNA-ribosyltransferase activity
MQE22_RS07670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MQE22_RS07675	COG1253	flavin adenine dinucleotide binding
MQE22_RS07690	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MQE22_RS07700	COG0285	dihydrofolate synthase activity
MQE22_RS07705	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MQE22_RS07710	COG0159	tryptophan synthase activity
MQE22_RS07715	COG0133	tryptophan synthase activity
MQE22_RS07720	COG0135	phosphoribosylanthranilate isomerase activity
MQE22_RS07725	COG0101	tRNA pseudouridine synthase activity
MQE22_RS07735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MQE22_RS07755	COG1763	Mo-molybdopterin cofactor biosynthetic process
MQE22_RS07770	COG0415	Belongs to the DNA photolyase family
MQE22_RS07780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MQE22_RS07785	COG0670	Belongs to the BI1 family
MQE22_RS07790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MQE22_RS07830	COG3609	addiction module antidote protein, CC2985 family
MQE22_RS07850	COG1530	ribonuclease E activity
MQE22_RS07855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MQE22_RS07860	COG0215	cysteine-tRNA ligase activity
MQE22_RS07865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MQE22_RS07880	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MQE22_RS07885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MQE22_RS07895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MQE22_RS07910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE22_RS07915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MQE22_RS07925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MQE22_RS07925	COG2755	lipolytic protein G-D-S-L family
MQE22_RS07930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MQE22_RS07930	COG2755	lipolytic protein G-D-S-L family
MQE22_RS07940	COG2132	Multicopper oxidase
MQE22_RS07975	COG1686	Belongs to the peptidase S11 family
MQE22_RS07995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MQE22_RS08040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MQE22_RS08050	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MQE22_RS08070	COG1215	transferase activity, transferring glycosyl groups
MQE22_RS08075	COG0463	Glycosyl transferase, family 2
MQE22_RS08080	COG2244	polysaccharide biosynthetic process
MQE22_RS08085	COG4636	protein conserved in cyanobacteria
MQE22_RS08095	COG3041	Addiction module toxin RelE StbE family
MQE22_RS08100	COG3077	Addiction module antitoxin, RelB DinJ family
MQE22_RS08130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MQE22_RS08145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE22_RS08150	COG1570	exodeoxyribonuclease VII activity
MQE22_RS08170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MQE22_RS08195	COG2326	polyphosphate kinase activity
MQE22_RS08200	COG0557	exoribonuclease II activity
MQE22_RS08215	COG3247	response to pH
MQE22_RS08220	COG2257	FlhB HrpN YscU SpaS Family
MQE22_RS08235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MQE22_RS08255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MQE22_RS08260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MQE22_RS08265	COG0740	serine-type endopeptidase activity
MQE22_RS08270	COG0544	peptidyl-prolyl cis-trans isomerase activity
MQE22_RS08275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MQE22_RS08280	COG0284	orotidine-5'-phosphate decarboxylase activity
MQE22_RS08285	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MQE22_RS08290	COG0776	regulation of translation
MQE22_RS08300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MQE22_RS08305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MQE22_RS08310	COG0287	Prephenate dehydrogenase
MQE22_RS08315	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MQE22_RS08325	COG1605	Chorismate mutase
MQE22_RS08325	COG0077	Prephenate dehydratase
MQE22_RS08330	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MQE22_RS08340	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MQE22_RS08345	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MQE22_RS08355	COG1475	DNA binding
MQE22_RS08360	COG1192	Involved in chromosome partitioning
MQE22_RS08375	COG2948	multi-organism process
MQE22_RS08420	COG3451	type IV secretory pathway VirB4
MQE22_RS08440	COG4962	Type ii secretion system protein e
MQE22_RS08450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MQE22_RS08460	COG1937	Protein conserved in bacteria
MQE22_RS08470	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MQE22_RS08510	COG1285	pathogenesis
MQE22_RS08525	COG3384	dioxygenase
MQE22_RS08530	COG2353	YceI-like domain
MQE22_RS08535	COG0655	NAD(P)H dehydrogenase (quinone) activity
MQE22_RS08540	COG1733	regulation of RNA biosynthetic process
MQE22_RS08600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MQE22_RS08605	COG2801	Transposase and inactivated derivatives
MQE22_RS08670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MQE22_RS08680	COG0629	single-stranded DNA binding
MQE22_RS08850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MQE22_RS08955	COG0741	lytic transglycosylase activity
MQE22_RS08955	COG1196	nuclear chromosome segregation
MQE22_RS08955	COG0739	heme binding
MQE22_RS09020	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MQE22_RS09025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MQE22_RS09030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MQE22_RS09050	COG1271	oxidase subunit
MQE22_RS09055	COG1294	oxidase, subunit
MQE22_RS09085	COG0655	NAD(P)H dehydrogenase (quinone) activity
MQE22_RS09095	COG0500	methyltransferase
MQE22_RS09110	COG0784	Response regulator, receiver
MQE22_RS09110	COG2205	protein histidine kinase activity
MQE22_RS09120	COG3706	GGDEF domain
MQE22_RS09170	COG0642	Histidine kinase
MQE22_RS09200	COG0463	Glycosyl transferase, family 2
MQE22_RS09215	COG1902	pentaerythritol trinitrate reductase activity
MQE22_RS09245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MQE22_RS09320	COG0470	DNA polymerase III
MQE22_RS09325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MQE22_RS09330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MQE22_RS09340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MQE22_RS09345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MQE22_RS09350	COG1028	Short-chain dehydrogenase reductase Sdr
MQE22_RS09355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MQE22_RS09360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MQE22_RS09365	COG0416	fatty acid biosynthetic process
MQE22_RS09370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MQE22_RS09380	COG0505	Belongs to the CarA family
MQE22_RS09390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MQE22_RS09395	COG1968	undecaprenyl-diphosphatase activity
MQE22_RS09400	COG2814	Major facilitator Superfamily
MQE22_RS09405	COG0109	protoheme IX farnesyltransferase activity
MQE22_RS09420	COG1845	cytochrome c oxidase, subunit III
MQE22_RS09425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MQE22_RS09440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MQE22_RS09445	COG0259	pyridoxamine-phosphate oxidase activity
MQE22_RS09455	COG0066	3-isopropylmalate dehydratase activity
MQE22_RS09465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MQE22_RS09470	COG0312	modulator of DNA gyrase
MQE22_RS09480	COG0347	Belongs to the P(II) protein family
MQE22_RS09485	COG0505	Belongs to the CarA family
MQE22_RS09490	COG0004	ammonium transporteR
MQE22_RS09515	COG3852	Histidine kinase
MQE22_RS09550	COG2308	Evidence 4 Homologs of previously reported genes of
MQE22_RS09565	COG0004	ammonium transporteR
MQE22_RS09570	COG0326	Molecular chaperone. Has ATPase activity
MQE22_RS09580	COG2201	protein-glutamate methylesterase activity
MQE22_RS09585	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MQE22_RS09595	COG0835	chemotaxis
MQE22_RS09600	COG0840	transmembrane signaling receptor activity
MQE22_RS09605	COG0643	Histidine kinase
MQE22_RS09605	COG2198	Histidine kinase
MQE22_RS09615	COG0745	RESPONSE REGULATOR receiver
MQE22_RS09625	COG1271	oxidase subunit
MQE22_RS09650	COG4372	Transposase
MQE22_RS09685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MQE22_RS09690	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MQE22_RS09705	COG3547	Transposase (IS116 IS110 IS902 family)
MQE22_RS09735	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MQE22_RS09740	COG1534	Rna-binding protein
MQE22_RS09745	COG0495	leucyl-tRNA aminoacylation
MQE22_RS09755	COG1466	dna polymerase III delta subunit
MQE22_RS09760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MQE22_RS09770	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MQE22_RS09780	COG0006	proline dipeptidase activity
MQE22_RS09795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MQE22_RS09795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MQE22_RS09810	COG0450	alkyl hydroperoxide reductase
MQE22_RS09815	COG1605	Chorismate mutase
MQE22_RS09815	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MQE22_RS09820	COG0114	fumarate hydratase activity
MQE22_RS09850	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MQE22_RS09855	COG1194	a g-specific adenine glycosylase
MQE22_RS09865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MQE22_RS09880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MQE22_RS09885	COG0497	DNA recombination
MQE22_RS09905	COG2204	response regulator
MQE22_RS09915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MQE22_RS09935	COG0297	glycogen (starch) synthase activity
MQE22_RS09940	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MQE22_RS09950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MQE22_RS09960	COG1388	LysM domain
MQE22_RS09960	COG1376	ErfK ybiS ycfS ynhG family protein
MQE22_RS09980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MQE22_RS10000	COG0577	efflux transmembrane transporter activity
MQE22_RS10000	COG1136	(ABC) transporter
MQE22_RS10010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE22_RS10015	COG1309	transcriptional regulator
MQE22_RS10025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MQE22_RS10025	COG1017	nitric oxide dioxygenase activity
MQE22_RS10045	COG3189	MarR family transcriptional regulator
MQE22_RS10050	COG1566	PFAM secretion protein HlyD family protein
MQE22_RS10055	COG1538	Outer membrane efflux protein
MQE22_RS10060	COG0477	Major facilitator Superfamily
MQE22_RS10065	COG3707	response regulator
MQE22_RS10075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MQE22_RS10075	COG1648	precorrin-2 dehydrogenase activity
MQE22_RS10080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MQE22_RS10085	COG0243	molybdopterin cofactor binding
MQE22_RS10090	COG2146	nitrite reductase [NAD(P)H] activity
MQE22_RS10095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MQE22_RS10105	COG2223	nitrite transmembrane transporter activity
MQE22_RS10110	COG1116	anion transmembrane transporter activity
MQE22_RS10110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MQE22_RS10115	COG1573	uracil-dna glycosylase
MQE22_RS10120	COG0583	DNA-binding transcription factor activity
MQE22_RS10125	COG0527	aspartate kinase activity
MQE22_RS10130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MQE22_RS10135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MQE22_RS10140	COG0137	argininosuccinate synthase activity
MQE22_RS10155	COG0328	RNA-DNA hybrid ribonuclease activity
MQE22_RS10165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MQE22_RS10170	COG0612	Peptidase, M16
MQE22_RS10175	COG1185	polyribonucleotide nucleotidyltransferase activity
MQE22_RS10180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MQE22_RS10185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MQE22_RS10190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MQE22_RS10195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MQE22_RS10200	COG2251	uridine kinase activity
MQE22_RS10200	COG0195	Participates in both transcription termination and antitermination
MQE22_RS10205	COG0779	Required for maturation of 30S ribosomal subunits
MQE22_RS10240	COG1376	ErfK ybiS ycfS ynhG family protein
MQE22_RS10240	COG1388	LysM domain
MQE22_RS10250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MQE22_RS10255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MQE22_RS10265	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MQE22_RS10275	COG0492	ferredoxin-NADP+ reductase activity
MQE22_RS10290	COG0585	pseudouridine synthase activity
MQE22_RS10295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MQE22_RS10300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MQE22_RS10305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MQE22_RS10310	COG0560	Phosphoserine phosphatase
MQE22_RS10315	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MQE22_RS10315	COG0678	peroxiredoxin activity
MQE22_RS10320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MQE22_RS10330	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MQE22_RS10350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MQE22_RS10355	COG2003	Belongs to the UPF0758 family
MQE22_RS10365	COG0756	dUTP diphosphatase activity
MQE22_RS10375	COG0717	Belongs to the dCTP deaminase family
MQE22_RS10380	COG0489	protein tyrosine kinase activity
MQE22_RS10390	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MQE22_RS10395	COG0484	heat shock protein binding
MQE22_RS10400	COG0443	Heat shock 70 kDa protein
MQE22_RS10405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MQE22_RS10410	COG1420	regulation of RNA biosynthetic process
MQE22_RS10415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MQE22_RS10420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MQE22_RS10425	COG0531	amino acid
MQE22_RS10455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MQE22_RS10470	COG1773	rubredoxin
MQE22_RS10490	COG1953	Uracil, thiamine, allantoin
MQE22_RS10505	COG0493	'glutamate synthase
MQE22_RS10505	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MQE22_RS10515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MQE22_RS10525	COG0583	DNA-binding transcription factor activity
MQE22_RS10565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MQE22_RS10590	COG0811	peptide transport
MQE22_RS10615	COG3046	protein related to deoxyribodipyrimidine photolyase
MQE22_RS10635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MQE22_RS10645	COG2211	Major facilitator Superfamily
MQE22_RS10655	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MQE22_RS10680	COG1671	Belongs to the UPF0178 family
MQE22_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
MQE22_RS10770	COG1178	ABC-type Fe3 transport system permease component
MQE22_RS10780	COG3842	ATPase activity
MQE22_RS10800	COG2885	chlorophyll binding
MQE22_RS10820	COG0776	regulation of translation
MQE22_RS10825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MQE22_RS10825	COG0072	phenylalanine-tRNA ligase activity
MQE22_RS10830	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MQE22_RS10835	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MQE22_RS10840	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MQE22_RS10845	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MQE22_RS10850	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MQE22_RS10865	COG1007	ATP synthesis coupled electron transport
MQE22_RS10880	COG0713	ATP synthesis coupled electron transport
MQE22_RS10885	COG0839	Belongs to the complex I subunit 6 family
MQE22_RS10890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS10895	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MQE22_RS10900	COG1034	ATP synthesis coupled electron transport
MQE22_RS10915	COG0649	NAD binding
MQE22_RS10920	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS10925	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS10930	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS10940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MQE22_RS10945	COG0149	triose-phosphate isomerase activity
MQE22_RS10950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MQE22_RS10955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MQE22_RS10960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MQE22_RS10965	COG0312	modulator of DNA gyrase
MQE22_RS10970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MQE22_RS10970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MQE22_RS10975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MQE22_RS10985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MQE22_RS10990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MQE22_RS10990	COG2813	Specifically methylates the guanine in position
MQE22_RS11000	COG2226	methyltransferase
MQE22_RS11005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MQE22_RS11010	COG0659	secondary active sulfate transmembrane transporter activity
MQE22_RS11045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MQE22_RS11050	COG0768	penicillin binding
MQE22_RS11055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MQE22_RS11070	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MQE22_RS11075	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MQE22_RS11080	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MQE22_RS11085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MQE22_RS11095	COG0501	Belongs to the peptidase M48B family
MQE22_RS11115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MQE22_RS11120	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MQE22_RS11135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MQE22_RS11140	COG3001	Fructosamine kinase
MQE22_RS11145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MQE22_RS11150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MQE22_RS11155	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MQE22_RS11160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MQE22_RS11195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MQE22_RS11200	COG0762	integral membrane protein
MQE22_RS11205	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MQE22_RS11215	COG1566	PFAM secretion protein HlyD family protein
MQE22_RS11250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MQE22_RS11250	COG0543	2 iron, 2 sulfur cluster binding
MQE22_RS11260	COG0390	transport system, permease component
MQE22_RS11275	COG2801	Transposase and inactivated derivatives
MQE22_RS11280	COG1192	Involved in chromosome partitioning
MQE22_RS11300	COG3436	PFAM IS66 Orf2 family protein
MQE22_RS11330	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MQE22_RS11335	COG2226	methyltransferase
MQE22_RS11340	COG2267	carboxylic ester hydrolase activity
MQE22_RS11345	COG0156	8-amino-7-oxononanoate synthase activity
MQE22_RS11350	COG1040	competence protein
MQE22_RS11355	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MQE22_RS11360	COG0477	Major facilitator Superfamily
MQE22_RS11365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MQE22_RS11370	COG1519	Transferase
MQE22_RS11380	COG0859	PFAM glycosyl transferase family 9
MQE22_RS11385	COG0463	Glycosyl transferase, family 2
MQE22_RS11405	COG0438	transferase activity, transferring glycosyl groups
MQE22_RS11415	COG0463	Glycosyl transferase, family 2
MQE22_RS11420	COG0494	nUDIX hydrolase
MQE22_RS11425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MQE22_RS11430	COG0653	protein targeting
MQE22_RS11440	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MQE22_RS11445	COG0625	glutathione transferase activity
MQE22_RS11465	COG2001	Belongs to the MraZ family
MQE22_RS11470	COG0275	rRNA processing
MQE22_RS11485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MQE22_RS11490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MQE22_RS11495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MQE22_RS11500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MQE22_RS11505	COG0772	Belongs to the SEDS family
MQE22_RS11510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MQE22_RS11515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MQE22_RS11520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MQE22_RS11525	COG1181	Belongs to the D-alanine--D-alanine ligase family
MQE22_RS11560	COG0583	DNA-binding transcription factor activity
MQE22_RS11565	COG3002	Belongs to the UPF0753 family
MQE22_RS11570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MQE22_RS11585	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS11590	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS11590	COG0649	NAD binding
MQE22_RS11590	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS11595	COG0649	NAD binding
MQE22_RS11595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS11600	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MQE22_RS11610	COG1034	ATP synthesis coupled electron transport
MQE22_RS11615	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MQE22_RS11620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS11630	COG0713	ATP synthesis coupled electron transport
MQE22_RS11635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MQE22_RS11640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MQE22_RS11645	COG1007	ATP synthesis coupled electron transport
MQE22_RS11655	COG0650	Formate hydrogenlyase subunit 4
MQE22_RS11665	COG0651	ATP synthesis coupled electron transport
MQE22_RS11670	COG3261	NADH dehydrogenase
MQE22_RS11670	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MQE22_RS11675	COG3260	NADH ubiquinone oxidoreductase 20
MQE22_RS11680	COG0651	ATP synthesis coupled electron transport
MQE22_RS11685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MQE22_RS11700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MQE22_RS11705	COG0406	alpha-ribazole phosphatase activity
MQE22_RS11810	COG4964	Belongs to the GSP D family
MQE22_RS11855	COG2885	chlorophyll binding
MQE22_RS11865	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MQE22_RS11880	COG2833	Protein of unknown function (DUF455)
MQE22_RS11910	COG0386	Belongs to the glutathione peroxidase family
MQE22_RS11940	COG2095	MarC family integral membrane protein
MQE22_RS11950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MQE22_RS11960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MQE22_RS11970	COG0217	transcriptional regulatory protein
MQE22_RS11975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MQE22_RS11980	COG0632	four-way junction helicase activity
MQE22_RS11985	COG2255	four-way junction helicase activity
MQE22_RS11990	COG0824	Thioesterase
MQE22_RS12010	COG0823	Involved in the tonB-independent uptake of proteins
MQE22_RS12015	COG1280	lysine exporter protein (LysE YggA)
MQE22_RS12020	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MQE22_RS12025	COG0602	queuosine metabolic process
MQE22_RS12035	COG2885	chlorophyll binding
MQE22_RS12040	COG0181	hydroxymethylbilane synthase activity
MQE22_RS12050	COG0113	porphobilinogen synthase activity
MQE22_RS12060	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MQE22_RS12080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MQE22_RS12105	COG2204	response regulator
MQE22_RS12115	COG2205	protein histidine kinase activity
MQE22_RS12120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MQE22_RS12125	COG0540	Belongs to the ATCase OTCase family
MQE22_RS12130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MQE22_RS12135	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MQE22_RS12140	COG1678	Uncharacterized ACR, COG1678
MQE22_RS12145	COG0189	ligase activity
MQE22_RS12160	COG0316	Belongs to the HesB IscA family
MQE22_RS12170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MQE22_RS12175	COG0022	dehydrogenase e1 component
MQE22_RS12175	COG0508	dehydrogenase complex catalyzes the overall conversion of
MQE22_RS12180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MQE22_RS12195	COG3300	MHYT domain
MQE22_RS12195	COG5001	Diguanylate cyclase
MQE22_RS12205	COG2200	EAL domain
MQE22_RS12210	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MQE22_RS12215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MQE22_RS12220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MQE22_RS12230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MQE22_RS12235	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MQE22_RS12240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MQE22_RS12245	COG1127	ABC transporter
MQE22_RS12250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MQE22_RS12255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MQE22_RS12270	COG1131	(ABC) transporter
MQE22_RS12275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MQE22_RS12280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MQE22_RS12290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MQE22_RS12305	COG0018	arginyl-trna synthetase
MQE22_RS12310	COG3264	Mechanosensitive ion channel
MQE22_RS12310	COG1511	domain protein
MQE22_RS12320	COG0583	DNA-binding transcription factor activity
MQE22_RS12330	COG0708	Exodeoxyribonuclease III
MQE22_RS12345	COG0625	glutathione transferase activity
MQE22_RS12355	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MQE22_RS12360	COG1047	Peptidyl-prolyl cis-trans
MQE22_RS12365	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MQE22_RS12370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MQE22_RS12375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MQE22_RS12395	COG0237	dephospho-CoA kinase activity
MQE22_RS12405	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MQE22_RS12440	COG0741	lytic transglycosylase activity
MQE22_RS12445	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MQE22_RS12460	COG0439	Biotin carboxylase
MQE22_RS12465	COG0511	ligase activity, forming carbon-carbon bonds
MQE22_RS12470	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MQE22_RS12475	COG0778	Nitroreductase
MQE22_RS12480	COG0488	(ABC) transporter
MQE22_RS12485	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MQE22_RS12495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MQE22_RS12500	COG1333	cytochrome c biogenesis protein
MQE22_RS12520	COG1611	Belongs to the LOG family
MQE22_RS12530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MQE22_RS12545	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MQE22_RS12550	COG3657	addiction module killer protein
MQE22_RS12575	COG2161	toxin-antitoxin pair type II binding
MQE22_RS12580	COG3344	reverse transcriptase
MQE22_RS12620	COG0165	Argininosuccinate lyase
MQE22_RS12640	COG0418	dihydroorotase activity
MQE22_RS12650	COG2885	chlorophyll binding
MQE22_RS12680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MQE22_RS12700	COG1393	Belongs to the ArsC family
MQE22_RS12710	COG0583	DNA-binding transcription factor activity
MQE22_RS12730	COG2885	chlorophyll binding
MQE22_RS12750	COG0277	FAD linked oxidase domain protein
MQE22_RS12755	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MQE22_RS12760	COG0792	nuclease activity
MQE22_RS12785	COG1196	nuclear chromosome segregation
MQE22_RS12800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MQE22_RS12820	COG4691	Plasmid stability protein
MQE22_RS12825	COG1487	ribonuclease activity
MQE22_RS12870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MQE22_RS12890	COG0776	regulation of translation
MQE22_RS12925	COG0431	NADPH-dependent FMN reductase
MQE22_RS12940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MQE22_RS12950	COG1595	DNA-templated transcription, initiation
MQE22_RS12970	COG1538	Outer membrane efflux protein
MQE22_RS12980	COG1131	(ABC) transporter
MQE22_RS12985	COG1131	(ABC) transporter
MQE22_RS12990	COG0842	Transport permease protein
MQE22_RS12995	COG0842	Transport permease protein
MQE22_RS13010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MQE22_RS13025	COG3220	belongs to the UPF0276 family
MQE22_RS13045	COG4232	protein-disulfide reductase activity
MQE22_RS13065	COG2814	Major facilitator Superfamily
MQE22_RS13075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MQE22_RS13075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MQE22_RS13090	COG2226	methyltransferase
MQE22_RS13120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MQE22_RS13150	COG0629	single-stranded DNA binding
MQE22_RS13155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MQE22_RS13155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MQE22_RS13170	COG3561	AntA/AntB antirepressor
MQE22_RS13195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MQE22_RS13240	COG4962	Type ii secretion system protein e
MQE22_RS13310	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MQE22_RS13375	COG2217	Heavy metal translocating P-type atpase
MQE22_RS13405	COG3451	type IV secretory pathway VirB4
MQE22_RS13435	COG4680	protein conserved in bacteria
MQE22_RS13475	COG3504	Conjugal transfer protein
MQE22_RS13490	COG0489	protein tyrosine kinase activity
MQE22_RS13495	COG1475	DNA binding
MQE22_RS13500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MQE22_RS13505	COG0433	COG0433 Predicted ATPase
MQE22_RS13520	COG0488	(ABC) transporter
MQE22_RS13535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MQE22_RS13540	COG0594	ribonuclease P activity
MQE22_RS13545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MQE22_RS13550	COG0706	membrane insertase activity
MQE22_RS13555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MQE22_RS13575	COG1560	Kdo2-lipid A biosynthetic process
MQE22_RS13580	COG0668	transmembrane transport
MQE22_RS13600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MQE22_RS13610	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MQE22_RS13625	COG0424	maF-like protein
MQE22_RS13630	COG1530	ribonuclease E activity
MQE22_RS13635	COG1555	photosystem II stabilization
MQE22_RS13645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MQE22_RS13650	COG0352	thiamine-phosphate diphosphorylase activity
MQE22_RS13665	COG0300	oxidoreductase activity
MQE22_RS13700	COG3668	Plasmid stabilization system
MQE22_RS13705	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MQE22_RS13725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MQE22_RS13740	COG1216	Glycosyl transferase, family 2
MQE22_RS13740	COG0438	transferase activity, transferring glycosyl groups